Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002035-TA|BGIBMGA002035-PA|IPR003961|Fibronectin, type
III, IPR007110|Immunoglobulin-like, IPR003599|Immunoglobulin subtype,
IPR003598|Immunoglobulin subtype 2, IPR008957|Fibronectin, type
III-like fold, IPR008972|Cupredoxin, IPR013098|Immunoglobulin I-set
(3427 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 165 2e-39
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 163 1e-38
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 162 2e-38
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 162 2e-38
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 138 3e-31
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 121 4e-26
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 111 3e-23
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 111 3e-23
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 111 3e-23
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 111 3e-23
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 111 6e-23
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 109 1e-22
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 109 1e-22
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 109 2e-22
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 109 2e-22
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 109 2e-22
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 109 2e-22
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 109 2e-22
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 109 2e-22
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 107 7e-22
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 107 7e-22
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 107 7e-22
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 105 2e-21
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 103 1e-20
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 103 1e-20
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 103 1e-20
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 103 1e-20
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 102 3e-20
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 101 3e-20
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 99 1e-19
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 99 1e-19
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 100 2e-19
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 98 6e-19
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 98 6e-19
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 97 7e-19
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 97 7e-19
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 97 7e-19
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 97 1e-18
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 97 1e-18
AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein. 96 2e-18
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 95 3e-18
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 95 3e-18
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 95 4e-18
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 93 2e-17
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 93 2e-17
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 93 2e-17
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 93 2e-17
AY358330-1|AAQ88696.1| 477|Homo sapiens papilin protein. 91 9e-17
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 90 1e-16
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 90 1e-16
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 90 1e-16
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 90 1e-16
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 89 2e-16
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 89 2e-16
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 89 2e-16
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 89 2e-16
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 89 2e-16
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 89 3e-16
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 89 3e-16
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 89 3e-16
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 89 3e-16
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 89 3e-16
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 89 3e-16
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 89 3e-16
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 87 8e-16
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 87 8e-16
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 87 8e-16
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 87 8e-16
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 87 8e-16
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 87 8e-16
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 87 1e-15
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 86 2e-15
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 86 2e-15
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 85 3e-15
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 85 4e-15
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 84 7e-15
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 84 7e-15
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 84 7e-15
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 83 1e-14
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 83 1e-14
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 83 1e-14
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 83 1e-14
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 83 1e-14
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 83 2e-14
AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific tit... 83 2e-14
AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein. 83 2e-14
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 83 2e-14
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein. 82 3e-14
BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein. 82 3e-14
BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein ... 82 3e-14
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 82 3e-14
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 81 5e-14
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 81 5e-14
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 81 5e-14
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 81 7e-14
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 81 7e-14
AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member... 81 9e-14
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 81 9e-14
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 81 9e-14
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 81 9e-14
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 81 9e-14
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 81 9e-14
BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein. 80 1e-13
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 80 1e-13
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 80 1e-13
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 80 1e-13
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 80 1e-13
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 80 1e-13
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 80 2e-13
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 80 2e-13
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 80 2e-13
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 80 2e-13
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 80 2e-13
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 80 2e-13
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 80 2e-13
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 80 2e-13
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 80 2e-13
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 80 2e-13
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 80 2e-13
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 79 3e-13
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 79 4e-13
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 79 4e-13
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 79 4e-13
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 79 4e-13
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 79 4e-13
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 79 4e-13
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 79 4e-13
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 79 4e-13
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 79 4e-13
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 79 4e-13
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 79 4e-13
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 78 5e-13
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 78 5e-13
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 78 5e-13
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 78 5e-13
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 78 5e-13
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 78 5e-13
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 78 6e-13
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 78 6e-13
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 78 6e-13
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 78 6e-13
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 77 9e-13
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 77 1e-12
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 77 1e-12
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 77 1e-12
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 77 1e-12
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 77 1e-12
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 76 2e-12
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 76 3e-12
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 76 3e-12
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 75 3e-12
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 75 3e-12
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 75 3e-12
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 75 3e-12
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 75 3e-12
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 75 3e-12
X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein. 74 1e-11
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 73 1e-11
BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein pr... 73 1e-11
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 73 1e-11
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 73 1e-11
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 73 1e-11
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 73 1e-11
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 73 2e-11
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 73 2e-11
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 73 2e-11
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 73 2e-11
AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein. 73 2e-11
AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth facto... 73 2e-11
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 73 2e-11
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 73 2e-11
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 73 2e-11
BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth facto... 73 2e-11
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 73 2e-11
AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein. 73 2e-11
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 73 2e-11
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 73 2e-11
AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor r... 73 2e-11
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 73 2e-11
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 72 3e-11
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 72 3e-11
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 72 3e-11
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 72 3e-11
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 72 4e-11
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 72 4e-11
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 71 6e-11
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 71 6e-11
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 71 6e-11
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 71 6e-11
AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens ... 71 6e-11
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 71 6e-11
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 71 6e-11
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 71 6e-11
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 71 7e-11
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 71 7e-11
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 71 7e-11
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 71 7e-11
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 71 7e-11
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 71 7e-11
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 71 1e-10
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 71 1e-10
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 71 1e-10
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 71 1e-10
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 71 1e-10
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 71 1e-10
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 71 1e-10
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 71 1e-10
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 71 1e-10
Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C ... 70 1e-10
X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding pr... 70 1e-10
U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding pr... 70 1e-10
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 70 1e-10
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 70 1e-10
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 70 1e-10
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 70 1e-10
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 70 1e-10
AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein ... 70 1e-10
AC115538-1|AAY40987.1| 103|Homo sapiens unknown protein. 70 1e-10
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 70 1e-10
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 70 2e-10
BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein. 70 2e-10
BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein. 70 2e-10
BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein. 70 2e-10
BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kin... 70 2e-10
BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kin... 70 2e-10
BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kin... 70 2e-10
BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kin... 70 2e-10
BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein. 70 2e-10
AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein ... 70 2e-10
AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein ... 70 2e-10
AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein ... 70 2e-10
AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein ... 70 2e-10
AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle... 70 2e-10
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 70 2e-10
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 69 2e-10
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 69 2e-10
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 69 3e-10
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 69 3e-10
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 69 3e-10
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 69 3e-10
M29273-1|AAA59545.1| 626|Homo sapiens MAG protein. 69 3e-10
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 69 3e-10
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 69 3e-10
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 69 3e-10
BC093045-1|AAH93045.1| 582|Homo sapiens myelin associated glyco... 69 3e-10
BC053347-1|AAH53347.1| 626|Homo sapiens myelin associated glyco... 69 3e-10
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 69 3e-10
AK223562-1|BAD97282.1| 626|Homo sapiens myelin associated glyco... 69 3e-10
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 69 3e-10
AC002132-1|AAB58805.1| 626|Homo sapiens MAG protein. 69 3e-10
AB209170-1|BAD92407.1| 661|Homo sapiens myelin associated glyco... 69 3e-10
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 69 3e-10
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 69 4e-10
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 69 4e-10
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 69 4e-10
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 69 4e-10
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 69 4e-10
AK222649-1|BAD96369.1| 626|Homo sapiens myelin associated glyco... 69 4e-10
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 69 4e-10
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 68 5e-10
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 68 5e-10
AK222680-1|BAD96400.1| 626|Homo sapiens myelin associated glyco... 68 5e-10
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 68 5e-10
AC007567-1|AAS07434.1| 383|Homo sapiens unknown protein. 68 5e-10
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 68 7e-10
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 67 9e-10
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 66 2e-09
X64699-1|CAA45940.1| 531|Homo sapiens titin protein. 66 3e-09
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 66 3e-09
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 66 3e-09
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 66 3e-09
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 66 3e-09
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 66 3e-09
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 66 3e-09
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 66 3e-09
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 66 3e-09
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 66 3e-09
U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H ... 65 4e-09
BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein ... 65 4e-09
AL590103-8|CAI12131.1| 207|Homo sapiens heparan sulfate proteog... 65 4e-09
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 65 4e-09
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 65 4e-09
BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,... 65 5e-09
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 65 5e-09
AY211921-1|AAO65174.1| 294|Homo sapiens sarcoma antigen NY-SAR-... 65 5e-09
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 65 5e-09
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 65 5e-09
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 65 5e-09
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 64 8e-09
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 64 8e-09
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 64 8e-09
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 64 8e-09
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 64 8e-09
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 64 8e-09
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 64 8e-09
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 64 8e-09
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 64 8e-09
AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens ... 64 8e-09
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 64 8e-09
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 64 8e-09
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 64 8e-09
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 64 8e-09
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 64 1e-08
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 64 1e-08
X69089-1|CAA48832.1| 1465|Homo sapiens 165kD protein protein. 63 1e-08
AL050093-1|CAB43265.1| 145|Homo sapiens hypothetical protein pr... 63 1e-08
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 63 1e-08
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 63 2e-08
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 62 3e-08
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 62 3e-08
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 62 3e-08
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 62 3e-08
AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein. 62 3e-08
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 62 3e-08
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 62 3e-08
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 62 3e-08
AY044449-1|AAK95951.1| 1907|Homo sapiens muscle alpha-kinase pro... 62 3e-08
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 62 3e-08
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 62 5e-08
X64698-1|CAA45939.1| 1100|Homo sapiens titin protein. 61 6e-08
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 61 6e-08
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 61 8e-08
X69090-1|CAA48833.1| 1451|Homo sapiens 190kD protein protein. 61 8e-08
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 61 8e-08
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 61 8e-08
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 61 8e-08
BC116183-1|AAI16184.1| 1589|Homo sapiens myomesin 1, 185kDa prot... 61 8e-08
AK125322-1|BAC86128.1| 1685|Homo sapiens protein ( Homo sapiens ... 61 8e-08
AJ621424-1|CAF18565.1| 1685|Homo sapiens myomesin 1 protein. 61 8e-08
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 60 1e-07
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 60 1e-07
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 60 1e-07
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 60 1e-07
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 60 1e-07
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 60 1e-07
DQ248309-1|ABB55264.1| 851|Homo sapiens rhabdomyosarcoma antige... 60 1e-07
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 60 1e-07
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 60 1e-07
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 60 1e-07
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 60 1e-07
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 60 1e-07
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 60 1e-07
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 60 2e-07
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 60 2e-07
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 60 2e-07
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 60 2e-07
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 60 2e-07
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 60 2e-07
AL390252-10|CAI13179.1| 354|Homo sapiens myosin binding protein... 60 2e-07
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 60 2e-07
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 60 2e-07
BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein pr... 59 2e-07
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 59 2e-07
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 59 3e-07
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 59 3e-07
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 59 3e-07
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 59 3e-07
AK128689-1|BAC87572.1| 175|Homo sapiens protein ( Homo sapiens ... 59 3e-07
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 59 3e-07
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 59 3e-07
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 59 3e-07
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 59 3e-07
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 58 4e-07
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 58 4e-07
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 58 4e-07
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 58 4e-07
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 58 4e-07
AJ314901-1|CAC85749.1| 183|Homo sapiens obscurin protein. 58 4e-07
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 58 4e-07
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 58 4e-07
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 58 4e-07
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 58 4e-07
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 58 4e-07
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 58 6e-07
U57099-1|AAC50599.1| 113|Homo sapiens APEG-1 protein protein. 58 6e-07
CR542201-1|CAG46998.1| 113|Homo sapiens APEG1 protein. 58 6e-07
BC006346-1|AAH06346.1| 113|Homo sapiens SPEG protein protein. 58 6e-07
AK126500-1|BAC86568.1| 170|Homo sapiens protein ( Homo sapiens ... 58 6e-07
AF195139-1|AAG33941.1| 717|Homo sapiens pinin protein. 58 6e-07
AC053503-3|AAY15052.1| 113|Homo sapiens unknown protein. 58 6e-07
BC132902-1|AAI32903.1| 354|Homo sapiens myosin binding protein ... 58 7e-07
BC132900-1|AAI32901.1| 354|Homo sapiens myosin binding protein ... 58 7e-07
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 57 1e-06
U11814-1|AAA68514.1| 366|Homo sapiens soluble keratinocyte grow... 57 1e-06
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 57 1e-06
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 57 1e-06
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 57 1e-06
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 57 1e-06
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 57 1e-06
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 57 1e-06
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 57 1e-06
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 57 1e-06
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 57 1e-06
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 57 1e-06
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 57 1e-06
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 165 bits (401), Expect = 2e-39
Identities = 195/750 (26%), Positives = 291/750 (38%), Gaps = 88/750 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E R+RG P P++TW ++ + I S GR+ G L I ED G YTC+A N
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
Query: 2774 WTDQITHFVNFTGR-ESQVSPNVVTAE-KTRIARQSLESR-------RPHFGNVLTDYQV 2824
Q+T + G Q+ VV+ R + ++E+R P F L V
Sbjct: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVV 172
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G +I G P +V WL+ G + V + G+ L + V + + G+Y
Sbjct: 173 KEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP-----EKDILISVGEDINI-SFRT 2937
TC + G M+A ++ +Q D + V + K++ + ++ + S
Sbjct: 232 TCLVVNGSGKASMSAELS-IQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
Query: 2938 QGEPKPKAVPERIPGEPCVVDG---GNNWVSLAWPKSDPQTT--APVLAYKVESWLIGA- 2991
+ K + P+R P + L K P+T PVL S + A
Sbjct: 291 AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
Query: 2992 --EGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIG--VGLAG 3047
+ R LG+ S K+ P + G G S + + + G
Sbjct: 351 RVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEG 407
Query: 3048 DR----PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
R P+F + P ++ +T C V G P P V W G V + G + N
Sbjct: 408 QRDSAFPKF-ESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEN 466
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L + D G YSC A+N G+ S W L+ ER A +E
Sbjct: 467 AGSHYLCLLKARTRDSGTYSCTASNAQGQVS-----------CSW----TLQVERLAVME 511
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
P F+ L+D V L C V G+P P+++W +G+ + Y + + + H
Sbjct: 512 --VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH 569
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--DKGIR--AYV---------APEFC 3270
+ P +D G Y A N G VSC + V K R Y+ AP F
Sbjct: 570 IQDALP---EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL L K+ +G ++ ++ V P V W +G ++ S R Q L +
Sbjct: 627 QGLSDL-KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLCIQE 684
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
V D G YTC A N G T + V EP +P FI KP
Sbjct: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTV------QEPH-----------DGTQPWFISKP 727
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RS A G +V+I C + GDP P V+WLRD
Sbjct: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
Score = 139 bits (336), Expect = 2e-31
Identities = 99/353 (28%), Positives = 160/353 (45%), Gaps = 19/353 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLE 2652
P F + + E VK C V P V W+ G + + + + G L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLC 473
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+L A DS YSCT N G +S S L+V + P+F+ ++D + + V
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C +RG P+P+ITW + + I +Y GV L I + PED GTYTC AEN+
Sbjct: 533 LQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ + +V ++S + + + P F L+D +V G + +
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYL------LPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGL-YTLALSDVTETESGLYTCRAWSA 2890
V++ G P V WL G + E F ++G ++L + +V ++G YTC AW++
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQE--SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G V A +TV +P DG + +P + + S+G+ + IS G+P P
Sbjct: 701 AGEVRTQAVLTVQEPH--DGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFP 750
Score = 102 bits (244), Expect = 3e-20
Identities = 96/350 (27%), Positives = 137/350 (39%), Gaps = 15/350 (4%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVP 3080
+ T N G S T + + P F +L ++ G+ L CSV+G PVP
Sbjct: 485 YSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPVP 543
Query: 3081 GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
+ W+ NG ++ R T + + L I+D +D G Y+C A N G+ S A +
Sbjct: 544 RITWLLNGQPIQY--ARSTCEAGVAE--LHIQDALPEDHGTYTCLAENALGQVSCSAWV- 598
Query: 3141 VVTDRTVWEADAKLKRERSAEVEGDYP--PQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
TV E + K E V P P F L D +V V +T QV G+PPP+
Sbjct: 599 -----TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V W +G E+ + + Q H+L I +D G Y A N++G V L V
Sbjct: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ P F + G + IS + P V W RDG L L
Sbjct: 714 EP-HDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
+ L L V AG Y N VG S + + + + PR
Sbjct: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/232 (27%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P F+ + P L I G TA V+G P P V W +NG + +
Sbjct: 31 EAPAFI-LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV-----------VTDRTVWEADAKLKR 3156
L I ++ +D G+Y+CEATN G L V V +T+ + +
Sbjct: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + G+ PP+F +L V+ R +C++ G P P+V+W K + R +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYV 3265
+ LEI N DD GVY N SG S L + D R++V
Sbjct: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 4/181 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F L+D ++GS+V +T V + P V W NG + + + +L +
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ Y+C N G + T A L V + + P F R +++
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ--PWFISKPRSVTASLGQSVLI 740
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C I G P P + W +D K + D G ++ D V L + P +G Y +N
Sbjct: 741 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNR 799
Query: 2773 V 2773
V
Sbjct: 800 V 800
Score = 70.1 bits (164), Expect = 1e-10
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 1149
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ PED G Y C A+N + + V T ++ S N E
Sbjct: 1150 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 1200
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 1201 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 1252
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W + V+ S+ K ++ R E +
Sbjct: 1253 ESVELFGKVTGTQP--ITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 1310 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 1369 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 1426 EKPEEPK 1432
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 1863 GNCSLIISDVCGDDDAKYTCKAVNSL 1888
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 1878 AKYTCKAVNSLGEATCTAELIVET 1901
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG + V YP VTW+R+G + R ++ G L + AV D G
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
Query: 3339 YTCTASNEVGRASTSGKVEVIGT--DQTSEPRI----------PPVVISPDVPYSKEPMF 3386
YTC A+N G + ++ V G+ Q +P + V P + P F
Sbjct: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKF 163
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
K +EG C++ G P+P V WL+
Sbjct: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 1804 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 53.2 bits (122), Expect = 2e-05
Identities = 62/275 (22%), Positives = 104/275 (37%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 1058 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 1116
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ +D G Y C A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALPEDRGLYKCVAKND 1175
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 48.4 bits (110), Expect = 5e-04
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 1087 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+P D Y C +N+ G S + V P+ E + P +R
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+T L EG + +C + P VTW + V L + +G+ LE+
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D Y+C V N +G S SA L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 29/248 (11%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR 2629
S S+ + R S T P F + EG+ K V +P VTW+R
Sbjct: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
Query: 2630 NGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
NG + + ++ + G +L + D +Y+C N +GA + L V SF
Sbjct: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Query: 2689 ASPIPPTFTRSIRDTFHLAENE----LVLEC---------RI---RGQ-----------P 2721
P ++++ D F + E + EC R+ GQ P
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P++TW K + + R +G+ L I +D G YTC N ++
Sbjct: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
Query: 2782 VNFTGRES 2789
++ G +S
Sbjct: 248 LSIQGLDS 255
Score = 44.4 bits (100), Expect = 0.007
Identities = 20/42 (47%), Positives = 24/42 (57%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
P F KP+S E +E TV CEV G PKP+V W + VR
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 1153
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
Score = 39.1 bits (87), Expect = 0.28
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 1800 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1850
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPD-VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
G V+++ + S+ + D +P ++ P FI PR+ +EG T E V G P+
Sbjct: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
Query: 3413 PDVYWLRD 3420
P V W R+
Sbjct: 62 PQVTWHRN 69
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 163 bits (396), Expect = 1e-38
Identities = 194/750 (25%), Positives = 291/750 (38%), Gaps = 88/750 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E R+RG P P++TW ++ + I S GR+ G L I ED G YTC+A N
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
Query: 2774 WTDQITHFVNFTGR-ESQVSPNVVTAE-KTRIARQSLESR-------RPHFGNVLTDYQV 2824
Q+T + G Q+ VV+ R + ++E+R P F L V
Sbjct: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVV 172
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G +I G P +V WL+ G + V + G+ L + V + + G+Y
Sbjct: 173 KEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP-----EKDILISVGEDINI-SFRT 2937
TC + G M+A ++ +Q D + V + K++ + ++ + S
Sbjct: 232 TCLVVNGSGKASMSAELS-IQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
Query: 2938 QGEPKPKAVPERIPGEPCVVDG---GNNWVSLAWPKSDPQTT--APVLAYKVESWLIGA- 2991
+ K + P+R P + L K P+T PVL S + A
Sbjct: 291 AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
Query: 2992 --EGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIG--VGLAG 3047
+ R LG+ S K+ P + G G S + + + G
Sbjct: 351 RVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEG 407
Query: 3048 DR----PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
R P+F + P ++ +T C V G P P V W G V + G + +
Sbjct: 408 QRDSAFPKF-ESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED 466
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L + D G YSC A+N G+ S W L+ ER A +E
Sbjct: 467 AGSHYLCLLKARTRDSGTYSCTASNAQGQVS-----------CSW----TLQVERLAVME 511
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
P F+ L+D V L C V G+P P+++W +G+ + Y + + + H
Sbjct: 512 --VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH 569
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--DKGIR--AYV---------APEFC 3270
+ P +D G Y A N G VSC + V K R Y+ AP F
Sbjct: 570 IQDALP---EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL L K+ +G ++ ++ V P V W +G ++ S R Q L +
Sbjct: 627 QGLSDL-KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLCIQE 684
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
V D G YTC A N G T + V EP +P FI KP
Sbjct: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTV------QEPH-----------DGTQPWFISKP 727
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RS A G +V+I C + GDP P V+WLRD
Sbjct: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
Score = 141 bits (341), Expect = 5e-32
Identities = 100/353 (28%), Positives = 160/353 (45%), Gaps = 19/353 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLE 2652
P F + + E VK C V P V W+ G + + + D G L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+L A DS YSCT N G +S S L+V + P+F+ ++D + + V
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C +RG P+P+ITW + + I +Y GV L I + PED GTYTC AEN+
Sbjct: 533 LQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ + +V ++S + + + P F L+D +V G + +
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYL------LPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGL-YTLALSDVTETESGLYTCRAWSA 2890
V++ G P V WL G + E F ++G ++L + +V ++G YTC AW++
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQE--SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G V A +TV +P DG + +P + + S+G+ + IS G+P P
Sbjct: 701 AGEVRTQAVLTVQEPH--DGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFP 750
Score = 102 bits (244), Expect = 3e-20
Identities = 96/350 (27%), Positives = 137/350 (39%), Gaps = 15/350 (4%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVP 3080
+ T N G S T + + P F +L ++ G+ L CSV+G PVP
Sbjct: 485 YSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPVP 543
Query: 3081 GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
+ W+ NG ++ R T + + L I+D +D G Y+C A N G+ S A +
Sbjct: 544 RITWLLNGQPIQY--ARSTCEAGVAE--LHIQDALPEDHGTYTCLAENALGQVSCSAWV- 598
Query: 3141 VVTDRTVWEADAKLKRERSAEVEGDYP--PQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
TV E + K E V P P F L D +V V +T QV G+PPP+
Sbjct: 599 -----TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V W +G E+ + + Q H+L I +D G Y A N++G V L V
Sbjct: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ P F + G + IS + P V W RDG L L
Sbjct: 714 EP-HDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
+ L L V AG Y N VG S + + + + PR
Sbjct: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/232 (27%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P F+ + P L I G TA V+G P P V W +NG + +
Sbjct: 31 EAPAFI-LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV-----------VTDRTVWEADAKLKR 3156
L I ++ +D G+Y+CEATN G L V V +T+ + +
Sbjct: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + G+ PP+F +L V+ R +C++ G P P+V+W K + R +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYV 3265
+ LEI N DD GVY N SG S L + D R++V
Sbjct: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 4/181 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F L+D ++GS+V +T V + P V W NG + + + +L +
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ Y+C N G + T A L V + + P F R +++
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ--PWFISKPRSVTASLGQSVLI 740
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C I G P P + W +D K + D G ++ D V L + P +G Y +N
Sbjct: 741 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNR 799
Query: 2773 V 2773
V
Sbjct: 800 V 800
Score = 70.1 bits (164), Expect = 1e-10
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 1149
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ PED G Y C A+N + + V T ++ S N E
Sbjct: 1150 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 1200
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 1201 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 1252
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W + V+ S+ K ++ R E +
Sbjct: 1253 ESVELFGKVTGTQP--ITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 1310 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 1369 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 1426 EKPEEPK 1432
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 1863 GNCSLIISDVCGDDDAKYTCKAVNSL 1888
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 1878 AKYTCKAVNSLGEATCTAELIVET 1901
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG + V YP VTW+R+G + R ++ G L + AV D G
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
Query: 3339 YTCTASNEVGRASTSGKVEVIGT--DQTSEPRI----------PPVVISPDVPYSKEPMF 3386
YTC A+N G + ++ V G+ Q +P + V P + P F
Sbjct: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKF 163
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
K +EG C++ G P+P V WL+
Sbjct: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 1804 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 53.2 bits (122), Expect = 2e-05
Identities = 62/275 (22%), Positives = 104/275 (37%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 1058 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 1116
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ +D G Y C A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALPEDRGLYKCVAKND 1175
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 48.4 bits (110), Expect = 5e-04
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 1087 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+P D Y C +N+ G S + V P+ E + P +R
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+T L EG + +C + P VTW + V L + +G+ LE+
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D Y+C V N +G S SA L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 29/248 (11%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR 2629
S S+ + R S T P F + EG+ K V +P VTW+R
Sbjct: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
Query: 2630 NGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
NG + + ++ + G +L + D +Y+C N +GA + L V SF
Sbjct: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Query: 2689 ASPIPPTFTRSIRDTFHLAENE----LVLEC---------RI---RGQ-----------P 2721
P ++++ D F + E + EC R+ GQ P
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P++TW K + + R +G+ L I +D G YTC N ++
Sbjct: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
Query: 2782 VNFTGRES 2789
++ G +S
Sbjct: 248 LSIQGLDS 255
Score = 44.4 bits (100), Expect = 0.007
Identities = 20/42 (47%), Positives = 24/42 (57%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
P F KP+S E +E TV CEV G PKP+V W + VR
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 1153
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
Score = 39.1 bits (87), Expect = 0.28
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 1800 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1850
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPD-VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
G V+++ + S+ + D +P ++ P FI PR+ +EG T E V G P+
Sbjct: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
Query: 3413 PDVYWLRD 3420
P V W R+
Sbjct: 62 PQVTWHRN 69
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 162 bits (393), Expect = 2e-38
Identities = 194/750 (25%), Positives = 291/750 (38%), Gaps = 88/750 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E R+RG P P++TW ++ + I S GR+ G L I ED G YTC+A N
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
Query: 2774 WTDQITHFVNFTGR-ESQVSPNVVTAE-KTRIARQSLESR-------RPHFGNVLTDYQV 2824
Q+T + G Q+ VV+ R + ++E+R P F L V
Sbjct: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVV 172
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G +I G P +V WL+ G + V + G+ L + V + + G+Y
Sbjct: 173 KEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP-----EKDILISVGEDINI-SFRT 2937
TC + G M+A ++ +Q D + V + K++ + ++ + S
Sbjct: 232 TCLVVNGSGKASMSAELS-IQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
Query: 2938 QGEPKPKAVPERIPGEPCVVDG---GNNWVSLAWPKSDPQTT--APVLAYKVESWLIGA- 2991
+ K + P+R P + L K P+T PVL S + A
Sbjct: 291 AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
Query: 2992 --EGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIG--VGLAG 3047
+ R LG+ S K+ P + G G S + + + G
Sbjct: 351 RVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEG 407
Query: 3048 DR----PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
R P+F + P ++ +T C V G P P V W G V + G + +
Sbjct: 408 QRDSAFPKF-ESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED 466
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L + D G YSC A+N G+ S W L+ ER A +E
Sbjct: 467 AGSHYLCLLKARTRDSGTYSCTASNAQGQVS-----------CSW----TLQVERLAVME 511
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
P F+ L+D V L C V G+P P+++W +G+ + Y + + + H
Sbjct: 512 --VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH 569
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--DKGIR--AYV---------APEFC 3270
+ P +D G Y A N G VSC + V K R Y+ AP F
Sbjct: 570 IQDALP---EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL L K+ +G ++ ++ V P V W +G ++ S R Q L +
Sbjct: 627 QGLSDL-KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLWIQE 684
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
V D G YTC A N G T + V EP +P FI KP
Sbjct: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTV------QEPH-----------DGTQPWFISKP 727
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RS A G +V+I C + GDP P V+WLRD
Sbjct: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
Score = 140 bits (338), Expect = 1e-31
Identities = 100/353 (28%), Positives = 160/353 (45%), Gaps = 19/353 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLE 2652
P F + + E VK C V P V W+ G + + + D G L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+L A DS YSCT N G +S S L+V + P+F+ ++D + + V
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C +RG P+P+ITW + + I +Y GV L I + PED GTYTC AEN+
Sbjct: 533 LQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ + +V ++S + + + P F L+D +V G + +
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYL------LPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGL-YTLALSDVTETESGLYTCRAWSA 2890
V++ G P V WL G + E F ++G ++L + +V ++G YTC AW++
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQE--SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNS 700
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G V A +TV +P DG + +P + + S+G+ + IS G+P P
Sbjct: 701 AGEVRTQAVLTVQEPH--DGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFP 750
Score = 102 bits (245), Expect = 2e-20
Identities = 96/350 (27%), Positives = 137/350 (39%), Gaps = 15/350 (4%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVP 3080
+ T N G S T + + P F +L ++ G+ L CSV+G PVP
Sbjct: 485 YSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPVP 543
Query: 3081 GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
+ W+ NG ++ R T + + L I+D +D G Y+C A N G+ S A +
Sbjct: 544 RITWLLNGQPIQY--ARSTCEAGVAE--LHIQDALPEDHGTYTCLAENALGQVSCSAWV- 598
Query: 3141 VVTDRTVWEADAKLKRERSAEVEGDYP--PQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
TV E + K E V P P F L D +V V +T QV G+PPP+
Sbjct: 599 -----TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V W +G E+ + + Q H+L I +D G Y A N++G V L V
Sbjct: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ P F + G + IS + P V W RDG L L
Sbjct: 714 EP-HDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
+ L L V AG Y N VG S + + + + PR
Sbjct: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/232 (27%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P F+ + P L I G TA V+G P P V W +NG + +
Sbjct: 31 EAPAFI-LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV-----------VTDRTVWEADAKLKR 3156
L I ++ +D G+Y+CEATN G L V V +T+ + +
Sbjct: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + G+ PP+F +L V+ R +C++ G P P+V+W K + R +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYV 3265
+ LEI N DD GVY N SG S L + D R++V
Sbjct: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261
Score = 71.7 bits (168), Expect = 4e-11
Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 4/181 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F L+D ++GS+V +T V + P V W NG + + + +L +
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 682
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ Y+C N G + T A L V + + P F R +++
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ--PWFISKPRSVTASLGQSVLI 740
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C I G P P + W +D K + D G ++ D V L + P +G Y +N
Sbjct: 741 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNR 799
Query: 2773 V 2773
V
Sbjct: 800 V 800
Score = 70.1 bits (164), Expect = 1e-10
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 1149
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ PED G Y C A+N + + V T ++ S N E
Sbjct: 1150 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 1200
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 1201 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 1252
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W + V+ S+ K ++ R E +
Sbjct: 1253 ESVELFGKVTGTQP--ITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 1310 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 1369 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 1426 EKPEEPK 1432
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 1803 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 1863 GNCSLIISDVCGDDDAKYTCKAVNSL 1888
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 1878 AKYTCKAVNSLGEATCTAELIVET 1901
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG + V YP VTW+R+G + R ++ G L + AV D G
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
Query: 3339 YTCTASNEVGRASTSGKVEVIGT--DQTSEPRI----------PPVVISPDVPYSKEPMF 3386
YTC A+N G + ++ V G+ Q +P + V P + P F
Sbjct: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKF 163
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
K +EG C++ G P+P V WL+
Sbjct: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 1804 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1862
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 1863 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 53.2 bits (122), Expect = 2e-05
Identities = 62/275 (22%), Positives = 104/275 (37%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 1058 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 1116
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ +D G Y C A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALPEDRGLYKCVAKND 1175
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 48.4 bits (110), Expect = 5e-04
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 1087 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+P D Y C +N+ G S + V P+ E + P +R
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+T L EG + +C + P VTW + V L + +G+ LE+
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D Y+C V N +G S SA L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 29/248 (11%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR 2629
S S+ + R S T P F + EG+ K V +P VTW+R
Sbjct: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
Query: 2630 NGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
NG + + ++ + G +L + D +Y+C N +GA + L V SF
Sbjct: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Query: 2689 ASPIPPTFTRSIRDTFHLAENE----LVLEC---------RI---RGQ-----------P 2721
P ++++ D F + E + EC R+ GQ P
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P++TW K + + R +G+ L I +D G YTC N ++
Sbjct: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
Query: 2782 VNFTGRES 2789
++ G +S
Sbjct: 248 LSIQGLDS 255
Score = 44.4 bits (100), Expect = 0.007
Identities = 20/42 (47%), Positives = 24/42 (57%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
P F KP+S E +E TV CEV G PKP+V W + VR
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 1153
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
Score = 39.1 bits (87), Expect = 0.28
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 1800 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1850
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPD-VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
G V+++ + S+ + D +P ++ P FI PR+ +EG T E V G P+
Sbjct: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
Query: 3413 PDVYWLRD 3420
P V W R+
Sbjct: 62 PQVTWHRN 69
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 162 bits (393), Expect = 2e-38
Identities = 194/750 (25%), Positives = 291/750 (38%), Gaps = 88/750 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E R+RG P P++TW ++ + I S GR+ G L I ED G YTC+A N
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
Query: 2774 WTDQITHFVNFTGR-ESQVSPNVVTAE-KTRIARQSLESR-------RPHFGNVLTDYQV 2824
Q+T + G Q+ VV+ R + ++E+R P F L V
Sbjct: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVV 172
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G +I G P +V WL+ G + V + G+ L + V + + G+Y
Sbjct: 173 KEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP-----EKDILISVGEDINI-SFRT 2937
TC + G M+A ++ +Q D + V + K++ + ++ + S
Sbjct: 232 TCLVVNGSGKASMSAELS-IQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
Query: 2938 QGEPKPKAVPERIPGEPCVVDG---GNNWVSLAWPKSDPQTT--APVLAYKVESWLIGA- 2991
+ K + P+R P + L K P+T PVL S + A
Sbjct: 291 AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
Query: 2992 --EGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIG--VGLAG 3047
+ R LG+ S K+ P + G G S + + + G
Sbjct: 351 RVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEG 407
Query: 3048 DR----PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
R P+F + P ++ +T C V G P P V W G V + G + +
Sbjct: 408 QRDSAFPKF-ESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED 466
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L + D G YSC A+N G+ S W L+ ER A +E
Sbjct: 467 AGSHYLCLLKARTRDSGTYSCTASNAQGQVS-----------CSW----TLQVERLAVME 511
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
P F+ L+D V L C V G+P P+++W +G+ + Y + + + H
Sbjct: 512 --VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH 569
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--DKGIR--AYV---------APEFC 3270
+ P +D G Y A N G VSC + V K R Y+ AP F
Sbjct: 570 IQDALP---EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL L K+ +G ++ ++ V P V W +G ++ S R Q L +
Sbjct: 627 QGLSDL-KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLWIQE 684
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
V D G YTC A N G T + V EP +P FI KP
Sbjct: 685 VFPEDTGTYTCEAWNSAGEVRTQAVLTV------QEPH-----------DGTQPWFISKP 727
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RS A G +V+I C + GDP P V+WLRD
Sbjct: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
Score = 140 bits (338), Expect = 1e-31
Identities = 100/353 (28%), Positives = 160/353 (45%), Gaps = 19/353 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLE 2652
P F + + E VK C V P V W+ G + + + D G L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+L A DS YSCT N G +S S L+V + P+F+ ++D + + V
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C +RG P+P+ITW + + I +Y GV L I + PED GTYTC AEN+
Sbjct: 533 LQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ + +V ++S + + + P F L+D +V G + +
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYL------LPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGL-YTLALSDVTETESGLYTCRAWSA 2890
V++ G P V WL G + E F ++G ++L + +V ++G YTC AW++
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQE--SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNS 700
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G V A +TV +P DG + +P + + S+G+ + IS G+P P
Sbjct: 701 AGEVRTQAVLTVQEPH--DGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFP 750
Score = 102 bits (245), Expect = 2e-20
Identities = 96/350 (27%), Positives = 137/350 (39%), Gaps = 15/350 (4%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVP 3080
+ T N G S T + + P F +L ++ G+ L CSV+G PVP
Sbjct: 485 YSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPVP 543
Query: 3081 GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
+ W+ NG ++ R T + + L I+D +D G Y+C A N G+ S A +
Sbjct: 544 RITWLLNGQPIQY--ARSTCEAGVAE--LHIQDALPEDHGTYTCLAENALGQVSCSAWV- 598
Query: 3141 VVTDRTVWEADAKLKRERSAEVEGDYP--PQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
TV E + K E V P P F L D +V V +T QV G+PPP+
Sbjct: 599 -----TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V W +G E+ + + Q H+L I +D G Y A N++G V L V
Sbjct: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ P F + G + IS + P V W RDG L L
Sbjct: 714 EP-HDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
+ L L V AG Y N VG S + + + + PR
Sbjct: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/232 (27%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P F+ + P L I G TA V+G P P V W +NG + +
Sbjct: 31 EAPAFI-LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV-----------VTDRTVWEADAKLKR 3156
L I ++ +D G+Y+CEATN G L V V +T+ + +
Sbjct: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + G+ PP+F +L V+ R +C++ G P P+V+W K + R +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYV 3265
+ LEI N DD GVY N SG S L + D R++V
Sbjct: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261
Score = 71.7 bits (168), Expect = 4e-11
Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 4/181 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F L+D ++GS+V +T V + P V W NG + + + +L +
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 682
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ Y+C N G + T A L V + + P F R +++
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ--PWFISKPRSVTASLGQSVLI 740
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C I G P P + W +D K + D G ++ D V L + P +G Y +N
Sbjct: 741 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNR 799
Query: 2773 V 2773
V
Sbjct: 800 V 800
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 1751 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1810
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 1811 GNCSLIISDVCGDDDAKYTCKAVNSL 1836
Score = 66.5 bits (155), Expect = 2e-09
Identities = 84/367 (22%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 1149
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ ED G Y C A+N + + V T ++ S N E
Sbjct: 1150 GSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 1200
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 1201 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 1252
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W ++ V+ S+ K ++ R E +
Sbjct: 1253 ESVELFGKVTGTQP--ITC-TWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYT 1309
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 1310 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 1369 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 1426 EKPEEPK 1432
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG + V YP VTW+R+G + R ++ G L + AV D G
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
Query: 3339 YTCTASNEVGRASTSGKVEVIGT--DQTSEPRI----------PPVVISPDVPYSKEPMF 3386
YTC A+N G + ++ V G+ Q +P + V P + P F
Sbjct: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKF 163
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
K +EG C++ G P+P V WL+
Sbjct: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Score = 58.8 bits (136), Expect = 3e-07
Identities = 27/84 (32%), Positives = 43/84 (51%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 1766 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1825
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A V T
Sbjct: 1826 AKYTCKAVNSLGEATCTAEHIVET 1849
Score = 56.0 bits (129), Expect = 2e-06
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 1752 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1810
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
G L ++ V D YTC A N +G A+ + + ++ T + E
Sbjct: 1811 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE-HIVETMEEGE 1854
Score = 55.6 bits (128), Expect = 3e-06
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E+ +E +G P F +L+D V + L CQV PP + W +G+ + K
Sbjct: 1088 EKRSESQGT-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIIL 1146
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Q+ ++ I L+D G+Y+ A+N++G C C + VD
Sbjct: 1147 SQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVD 1188
Score = 54.0 bits (124), Expect = 9e-06
Identities = 62/275 (22%), Positives = 105/275 (38%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 1058 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 1116
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ ++D G Y C A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALLEDRGLYKCVAKND 1175
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENGSKL 1295
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+T L EG + +C + P VTW + V L + +G+ LE+
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D Y+C V N +G S SA L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 47.2 bits (107), Expect = 0.001
Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 1746 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1805
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C +V+
Sbjct: 1806 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1848
Score = 46.0 bits (104), Expect = 0.002
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 1756 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1815
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSA 2679
+ + D A+Y+C N G + +A
Sbjct: 1816 IISDVCGDDDAKYTCKAVNSLGEATCTA 1843
Score = 45.6 bits (103), Expect = 0.003
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 1756 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1815
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A V + +G+
Sbjct: 1816 IISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGE 1856
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 29/248 (11%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR 2629
S S+ + R S T P F + EG+ K V +P VTW+R
Sbjct: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
Query: 2630 NGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
NG + + ++ + G +L + D +Y+C N +GA + L V SF
Sbjct: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Query: 2689 ASPIPPTFTRSIRDTFHLAENE----LVLEC---------RI---RGQ-----------P 2721
P ++++ D F + E + EC R+ GQ P
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P++TW K + + R +G+ L I +D G YTC N ++
Sbjct: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
Query: 2782 VNFTGRES 2789
++ G +S
Sbjct: 248 LSIQGLDS 255
Score = 44.4 bits (100), Expect = 0.007
Identities = 20/42 (47%), Positives = 24/42 (57%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
P F KP+S E +E TV CEV G PKP+V W + VR
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 1087 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+ D Y C +N+ G S + V P+ E + P +R
Sbjct: 1145 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 1153
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 1154 SVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
Score = 38.3 bits (85), Expect = 0.48
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 1149 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 1748 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1798
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPD-VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
G V+++ + S+ + D +P ++ P FI PR+ +EG T E V G P+
Sbjct: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
Query: 3413 PDVYWLRD 3420
P V W R+
Sbjct: 62 PQVTWHRN 69
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 138 bits (334), Expect = 3e-31
Identities = 188/779 (24%), Positives = 294/779 (37%), Gaps = 124/779 (15%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P T L D EG + C V S +D V+WY + +R + LE+
Sbjct: 10 PAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 68
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANL-----------KVYPSFEAS-PIPPTFTRSIR 2701
A P D Y+ N G +S++ANL ++ E P R I
Sbjct: 69 AEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKI- 127
Query: 2702 DTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
+ +A L C I+ P + WFK ++I + + + + L I
Sbjct: 128 EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVV 186
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D G YTCKA N + T + T P ++ K+ LT
Sbjct: 187 DCGEYTCKASNEYGSVSCTATLTVT---EAYPPTFLSRPKS-----------------LT 226
Query: 2821 DYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
+ G + G P W ++G +++ N R+ + + L LS++T +
Sbjct: 227 TFV---GKAAKFICTVTGTPVIETIWQKDGAALSPS-PNWRISDAENKHILELSNLTIQD 282
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQG 2939
G+Y+C+A + G +D+ +I+ +P F +
Sbjct: 283 RGVYSCKASNKFG-------------ADICQAELIIIDKPH--------------FIKEL 315
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP A+ +++ E C VD V++ W K D Q P YK I E +E
Sbjct: 316 EPVQSAINKKVHLE-CQVDEDRK-VTVTWSK-DGQKLPPGKDYK-----ICFEDKIATLE 367
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
+ + LK Y T N G SS S+++ V + P FV +
Sbjct: 368 IPLA--------KLKDSGTYV--CTASNEAG---SSSCSATVTVR---EPPSFVKKVDPS 411
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+L GE+A L C +KG PV V W KN E+ E + + F + L I D+ ++D
Sbjct: 412 YLMLPGESARLHCKLKGSPVIQVTWFKNNKELSE-SNTVRMYFVNSEAILDITDVKVEDS 470
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G YSCEA N G S S E+ PP F L +
Sbjct: 471 GSYSCEAVNDVGSDSC-----------------------STEIVIKEPPSFIKTLEPADI 507
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
L C+V G+ P ++SW+KD +++ K+ + + LEI N D G YE
Sbjct: 508 VRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYE 567
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
N G C ++ + P F ++ L L G + + A V + V
Sbjct: 568 CVVANEVGKCGCMATHLLKE------PPTFVKKVDDLIAL-GGQTVTLQAAVRGSEPISV 620
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
TW + +R + M+ +G L + V G YTC A NE G ++ G++ V
Sbjct: 621 TWMKGQEVIREDGKIKMSFS-NGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIV 678
Score = 121 bits (292), Expect = 4e-26
Identities = 103/387 (26%), Positives = 165/387 (42%), Gaps = 36/387 (9%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
S +SS+ + G P F DI + + GE+A+ C V G V W K+ E+
Sbjct: 4802 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRS- 4860
Query: 3095 AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL 3154
G+ + LT+ ++ D G+Y+C A N GK S A+L +
Sbjct: 4861 GGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI------------- 4907
Query: 3155 KRERSAEVEGDYPPQFTMRLRDRRVQATY--PVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
+ER PP FT RL + V+ T +L +V GS P V+WYK+ E+
Sbjct: 4908 -KERLI------PPSFTKRLSET-VEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTS 4959
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG 3272
L++ ++D G+Y N++G+ C +V+ + + P F
Sbjct: 4960 NCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKP---PVFDQH 5016
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L P+ + EG+ +++S V+ + + W + G ++PS R + G L L V
Sbjct: 5017 LTPV-TVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF-ASGTAVLELRDVA 5074
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D+G Y C ASN G +T KV + +P + P V F+ +P+S
Sbjct: 5075 KADSGDYVCKASNVAGSDTTKSKVTI-----KDKPAVAPATKKAAV--DGRLFFVSEPQS 5127
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWLR 3419
E T +V GDP P+V W +
Sbjct: 5128 IRVVEKTTATFIAKVGGDPIPNVKWTK 5154
Score = 121 bits (291), Expect = 5e-26
Identities = 90/295 (30%), Positives = 131/295 (44%), Gaps = 29/295 (9%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +K+ G+T L C+V G P W K+G E+ + S FN L I ++
Sbjct: 4257 PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG-LKIINVAP 4315
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G YS E N GK S A L V +DRTV PP FT +L++
Sbjct: 4316 SDSGVYSFEVQNPVGKDSCTASLQV-SDRTV-------------------PPSFTRKLKE 4355
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+ V + C+V GSPP VSW+ +G E+ ++ + L + D G
Sbjct: 4356 TNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSG 4415
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G+ C L V + P F +P+ L G + +++V+ P
Sbjct: 4416 DYTCIATNMAGSDECSAPLTVRE------PPSFVQKPDPMDVL-TGTNVTFTSIVKGTPP 4468
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
V+W++ L P R ++L+ D EL L V T +G YTC SNE G+AS
Sbjct: 4469 FSVSWFKGSSELVPGDRCNVSLE-DSVAELELFDVDTSQSGEYTCIVSNEAGKAS 4522
Score = 113 bits (273), Expect = 8e-24
Identities = 100/371 (26%), Positives = 144/371 (38%), Gaps = 52/371 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV P + +L G T VKG P V W K E+ R L
Sbjct: 4440 PSFVQ-KPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVP-GDRCNVSLEDSVAEL 4497
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ D++ G Y+C +N GKAS L + P +
Sbjct: 4498 ELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKA-----------------------PAK 4534
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F RL D ++ P+ L G+PP V+W K+G V +R N E+ LEI
Sbjct: 4535 FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPS 4594
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ ++D G Y N SG SC +++ P F LEP+ K+ GD +
Sbjct: 4595 STVEDAGQYNCYIENASGKDSCSAQILI------LEPPYFVKQLEPV-KVSVGDSASLQC 4647
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
+ P +GV+WY+ +LRP+ M R+ L V D+G Y C A N VG
Sbjct: 4648 QLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLVFNQVDINDSGEYICKAENSVGE 4706
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
S S + V E ++P P F R+ R + G V+ +C + G
Sbjct: 4707 VSASTFLTV------QEQKLP-------------PSFSRQLRDVQETVGLPVVFDCAISG 4747
Query: 3410 DPKPDVYWLRD 3420
V W +D
Sbjct: 4748 SEPISVSWYKD 4758
Score = 113 bits (271), Expect = 1e-23
Identities = 84/300 (28%), Positives = 139/300 (46%), Gaps = 32/300 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L C+V + + + W+++G L + KY+ + + L+++N PSDS YS
Sbjct: 4265 GDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFE 4324
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
V+N G S +A+L+V +PP+FTR +++T L+ + +V+EC++ G P ++W
Sbjct: 4325 VQNPVGKDSCTASLQV----SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSW 4380
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
F + +I S +YQ L D C L ++ DSG YTC A N +D+ + T R
Sbjct: 4381 FHEGNEISSGRKYQT-TLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECS--APLTVR 4437
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWL 2846
E P+ V ++P +VLT G + ++G P V W
Sbjct: 4438 E---PPSFV--------------QKPDPMDVLT------GTNVTFTSIVKGTPPFSVSWF 4474
Query: 2847 REGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPS 2906
+ G S V +E + L L DV ++SG YTC + G + + P+
Sbjct: 4475 K-GSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA 4533
Score = 112 bits (269), Expect = 2e-23
Identities = 100/363 (27%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L++ G A TC ++ P W K G E+ E + + + + + + L I + D
Sbjct: 130 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE-SDKCSIRSSKYISSLEILRTQVVDC 188
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C+A+N +G S A L TV EA YPP F R +
Sbjct: 189 GEYTCKASNEYGSVSCTATL------TVTEA---------------YPPTFLSRPKSLTT 227
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ C V G+P + W KDG + E H LE++ + D GVY
Sbjct: 228 FVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYS 287
Query: 3240 VTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N GA C L ++DK P F LEP+ ++ + V+ V
Sbjct: 288 CKASNKFGADICQAELIIIDK-------PHFIKELEPVQSA-INKKVHLECQVDEDRKVT 339
Query: 3299 VTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG +L P + I D+ +E+ LA + +D+G Y CTASNE G +S S V
Sbjct: 340 VTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKL--KDSGTYVCTASNEAGSSSCSATVT 397
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V R PP + +P ++ P G++ + C++ G P V W
Sbjct: 398 V---------REPPSFVK-----KVDPSYLMLP-------GESARLHCKLKGSPVIQVTW 436
Query: 3418 LRD 3420
++
Sbjct: 437 FKN 439
Score = 111 bits (266), Expect = 6e-23
Identities = 100/373 (26%), Positives = 161/373 (43%), Gaps = 52/373 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV L L+ G++ +L C V G P V W K ++ T F L
Sbjct: 2744 PYFVTELE-PLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRT-YFTNNVATL 2801
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+NI+D G Y+C+A N+ G AS+ +TV+ E PP
Sbjct: 2802 VFNKVNINDSGEYTCKAENSIGTASS---------KTVFRIQ-----------ERQLPPS 2841
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F +L+D PV LTC++ GS P +V WY+DG + + + TL+I
Sbjct: 2842 FARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQ 2901
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T+L G Y +A N G S L + + +P F ++P+ + G+
Sbjct: 2902 TDLSHSGQYSCSASNPLGTASSSARLTAREPKK---SPFF--DIKPVSIDVIAGESADFE 2956
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
V + +TW +D +RP +T + L + V D+G YTC A+N+VG
Sbjct: 2957 CHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP-HLRILKVGKGDSGQYTCQATNDVG 3015
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE-AREGDTVIIECEV 3407
+ S ++ V EP P F++K +S+ A++G+++ +EC++
Sbjct: 3016 KDMCSAQLSV------KEP----------------PKFVKKLEASKVAKQGESIQLECKI 3053
Query: 3408 VGDPKPDVYWLRD 3420
G P+ V W R+
Sbjct: 3054 SGSPEIKVSWFRN 3066
Score = 109 bits (263), Expect = 1e-22
Identities = 94/369 (25%), Positives = 148/369 (40%), Gaps = 53/369 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L G+ A C+V G PV +W K+G + S L + ++ I
Sbjct: 222 PKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHI-LELSNLTI 280
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G YSC+A+N G A L ++ D+ P F L
Sbjct: 281 QDRGVYSCKASNKFGADICQAELIII-DK----------------------PHFIKELEP 317
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+ V L CQV V+W KDG+++ K +++ TLEI L D G
Sbjct: 318 VQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSG 377
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y TA N +G+ SC + V + P F ++P Y + G+ R+ ++ P
Sbjct: 378 TYVCTASNEAGSSSCSATVTVRE------PPSFVKKVDPSYLMLPGESARLHCKLKGSPV 431
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ VTW+++ L S M I L + V D+G Y+C A N+VG S S ++
Sbjct: 432 IQVTWFKNNKELSESNTVRMYFVNSEAI-LDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 490
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
+ EP P FI+ ++ G +++CEV G ++
Sbjct: 491 VI------KEP----------------PSFIKTLEPADIVRGTNALLQCEVSGTGPFEIS 528
Query: 3417 WLRDFLKVR 3425
W +D ++R
Sbjct: 529 WFKDKKQIR 537
Score = 109 bits (262), Expect = 2e-22
Identities = 98/353 (27%), Positives = 153/353 (43%), Gaps = 43/353 (12%)
Query: 2581 SEKRTLSRNSTRK--PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL 2638
+ +T+ R R+ P F+ L D G V LTC + S+ V WYR+GVLL +
Sbjct: 2825 ASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHE 2884
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANL-----KVYPSFEASPIP 2693
+ VD + TL++L S S +YSC+ N G S+SA L K P F+ P+
Sbjct: 2885 NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPV- 2943
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
SI D +A EC + G +ITW KD+K+I G Y L
Sbjct: 2944 -----SI-DV--IAGESADFECHVTGAQPMRITWSKDNKEIRPGGNY-TITCVGNTPHLR 2994
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I DSG YTC+A N V D + ++ + V E +++A+Q
Sbjct: 2995 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSV----KEPPKFVKKLEASKVAKQ------- 3043
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
G +I L+ +I G P +V W R + E ++ F+ + L +
Sbjct: 3044 -------------GESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFI-NSVALLTI 3089
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILI 2925
++ + +SG Y C A + G+ + A+TV P KP+ + D+++
Sbjct: 3090 NEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVIL 3142
Score = 109 bits (261), Expect = 2e-22
Identities = 104/378 (27%), Positives = 156/378 (41%), Gaps = 52/378 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F++ L ++ + GE A L C V G P + W K H A QF L
Sbjct: 3685 PYFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISWYKE-HTKLRSAPAYKMQFKNNVASL 3742
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I ++ D G YSC+A N+ G ++ A L + K ++ PP
Sbjct: 3743 VINKVDHSDVGEYSCKADNSVGAVASSAVLVI-----------KARK---------LPPF 3782
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F +L+D +PV C++ GS P +VSWYKDG + D TL+I
Sbjct: 3783 FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQ 3842
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T+ G Y +A N G S L++ + + P F L+P+ L G+
Sbjct: 3843 TDQSHIGQYNCSASNPLGTASSSAKLILSE----HEVPPF-FDLKPVSVDLALGESGTFK 3897
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
V + +TW +D +RP MTL + L + V DAG YTC ASN G
Sbjct: 3898 CHVTGTAPIKITWAKDNREIRPGGNYKMTL-VENTATLTVLKVGKGDAGQYTCYASNIAG 3956
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE-AREGDTVIIECEV 3407
+ S S ++ V EP P FI+K S ++ + EC++
Sbjct: 3957 KDSCSAQLGV------QEP----------------PRFIKKLEPSRIVKQDEFTRYECKI 3994
Query: 3408 VGDPKPDVYWLRDFLKVR 3425
G P+ V W +D +++
Sbjct: 3995 GGSPEIKVLWYKDETEIQ 4012
Score = 107 bits (258), Expect = 5e-22
Identities = 93/363 (25%), Positives = 143/363 (39%), Gaps = 54/363 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L+G + + C V G P V W G+E+ T+ + C LT+ + D G Y
Sbjct: 4359 LSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDN-TCALTVNMLEESDSGDY 4417
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+C ATN G A L V RE PP F + V
Sbjct: 4418 TCIATNMAGSDECSAPLTV--------------RE---------PPSFVQKPDPMDVLTG 4454
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
V T V G+PP VSW+K E+V R N ++ LE+ + G Y
Sbjct: 4455 TNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIV 4514
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
N +G SC L + +F L Y + +G L + P + VTW
Sbjct: 4515 SNEAGKASCTTHLYIK------APAKFVKRLND-YSIEKGKPLILEGTFTGTPPISVTWK 4567
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
++G+ + PS+R +T I L + + T DAG Y C N G+ S S ++ ++
Sbjct: 4568 KNGINVTPSQRCNITTTEKSPI-LEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL--- 4623
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
EP P F+++ + GD+ ++C++ G P+ V W +
Sbjct: 4624 ---EP----------------PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDT 4664
Query: 3423 KVR 3425
K+R
Sbjct: 4665 KLR 4667
Score = 105 bits (251), Expect = 4e-21
Identities = 84/321 (26%), Positives = 130/321 (40%), Gaps = 37/321 (11%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+ A +G ++L C + S + V+W+RN L KY ++ + L + A DS
Sbjct: 3039 KVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSG 3098
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y C N G S S L V PP FT+ L ++++L+C I G P
Sbjct: 3099 DYICEAHNGVGDASCSTALTV-------KAPPVFTQKPSPVGALKGSDVILQCEISGTPP 3151
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
++ W KD KQ+ + +++ L I N D G Y CKA N V +D + V
Sbjct: 3152 FEVVWVKDRKQVRNSKKFK-ITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSV 3210
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PT 2841
F P F L+D G + L+ + G P
Sbjct: 3211 KF-------------------------KEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPI 3245
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
V WL++ V N R+ + TL L + SG Y C+ + G + +A +T
Sbjct: 3246 SVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLT 3305
Query: 2902 VVQPSDLDGKP---AVIVGRP 2919
V++P+ + KP V G P
Sbjct: 3306 VLEPARIIEKPEPMTVTTGNP 3326
Score = 104 bits (250), Expect = 5e-21
Identities = 105/399 (26%), Positives = 165/399 (41%), Gaps = 46/399 (11%)
Query: 3027 NRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK 3086
N Y S + S S + L + P FV L +K+ G++A+L C + G P GV W K
Sbjct: 4604 NCYIENASGKDSCSAQI-LILEPPYFVKQLE-PVKVSVGDSASLQCQLAGTPEIGVSWYK 4661
Query: 3087 NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRT 3146
++ F L ++I+D G Y C+A N+ G+ S L V
Sbjct: 4662 GDTKLRPTT-TYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV----- 4715
Query: 3147 VWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE 3206
+ KL PP F+ +LRD + PV C + GS P VSWYKDG+
Sbjct: 4716 ---QEQKL------------PPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK 4760
Query: 3207 EVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA 3266
+ + TL I T+ G Y TA N G+ S L++ +G
Sbjct: 4761 PLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN---P 4817
Query: 3267 PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIEL 3326
P F L P+ + G+ V + V+W +D +R + ++ + L
Sbjct: 4818 PFFDIRLAPVDAV-VGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISY-LENSAHL 4875
Query: 3327 ALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF 3386
+ V D+G YTC A NEVG+ S + ++ + E IPP ++K
Sbjct: 4876 TVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI------KERLIPP-------SFTK---- 4918
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
R + E EG++ +E V G V W ++ ++++
Sbjct: 4919 -RLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQ 4956
Score = 103 bits (248), Expect = 9e-21
Identities = 84/329 (25%), Positives = 140/329 (42%), Gaps = 42/329 (12%)
Query: 2615 CSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGA 2674
C + S + V WY++ + K+R VD + LE+ N DS +Y+C N G+
Sbjct: 3992 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGS 4051
Query: 2675 ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI 2734
S+S +LKV PP F + L ++ LEC ++G P ++W+KD +++
Sbjct: 4052 ASSSTSLKVKE-------PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKREL 4104
Query: 2735 PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPN 2794
S +Y+ + + + I N D G Y CKA N V +D
Sbjct: 4105 RSGKKYK-IMSENFLTSIHILNVDAADIGEYQCKATNDVGSD------------------ 4145
Query: 2795 VVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVT 2853
T + +L++ P F L+D G + LQ I G P V W ++ +
Sbjct: 4146 ------TCVGSIALKA-PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIV 4198
Query: 2854 EVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPA 2913
N + + + TL S V +G YTC+ + G + A ++V++ PA
Sbjct: 4199 RESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE-------PA 4251
Query: 2914 VIVGRPEKDILISVGEDINISFRTQGEPK 2942
IV +PE I ++ G+ + G P+
Sbjct: 4252 TIVEKPE-SIKVTTGDTCTLECTVAGTPE 4279
Score = 103 bits (248), Expect = 9e-21
Identities = 89/350 (25%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS L D G V C++ S +V+WY++G L + + +D TL +
Sbjct: 4722 PSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 4781
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
S + +YSCT N G+ S+SA L PP F + +
Sbjct: 4782 FKTDRSLAGQYSCTATNPIGSASSSARL----ILTEGKNPPFFDIRLAPVDAVVGESADF 4837
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
EC + G K++W KD ++I S G+YQ YL + L + DSG YTC A N V
Sbjct: 4838 ECHVTGTQPIKVSWAKDSREIRSGGKYQISYL-ENSAHLTVLKVDKGDSGQYTCYAVNEV 4896
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
D T +N +E + P+ T+ +++E G + L+
Sbjct: 4897 GKDSCTAQLNI--KERLIPPSF-----TKRLSETVEE--------------TEGNSFKLE 4935
Query: 2834 VEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G P V W + + + N + + L + ++GLYTC+ + G
Sbjct: 4936 GRVAGSQPITVAWYKNNIEI-QPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAG 4994
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQG-EP 2941
+ ++I + +P KP V + + +S GE + +S QG EP
Sbjct: 4995 SALCTSSIVIKEPK----KPPVF-DQHLTPVTVSEGEYVQLSCHVQGSEP 5039
Score = 103 bits (247), Expect = 1e-20
Identities = 76/304 (25%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L C V + + +V WY++G LL + K++ + + +L +L+ D+
Sbjct: 2379 TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGT 2438
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+ V+N G S +A + V +PP+FTR +++T + +LEC++ G
Sbjct: 2439 YTFQVQNNVGKSSCTAVVDV----SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPI 2494
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ WF + +I S +YQ + +D VC L +++ D G YTC A N +D+
Sbjct: 2495 SVAWFHEKTKIVSGAKYQTTF-SDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECR---- 2549
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
V+T ++ P F +V G + IRG P +
Sbjct: 2550 ----------AVLTVQEP-----------PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFK 2588
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V W R R + + R ++ E + L L ++ ++SG YTC + G + V
Sbjct: 2589 VNWFRGARELVKGDR-CNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 2647
Query: 2903 VQPS 2906
+P+
Sbjct: 2648 KEPA 2651
Score = 101 bits (243), Expect = 3e-20
Identities = 80/295 (27%), Positives = 126/295 (42%), Gaps = 36/295 (12%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KP F L + +V L C V TVTW ++G L Y+ D + TLE
Sbjct: 308 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 367
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ A DS Y CT NE G+ S SA + V PP+F + + ++ + E
Sbjct: 368 IPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE-------PPSFVKKVDPSYLMLPGESA 420
Query: 2713 -LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C+++G P+ ++TWFK++K++ S+ Y + L I + EDSG+Y+C+A N
Sbjct: 421 RLHCKLKGSPVIQVTWFKNNKEL-SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVN 479
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V +D S +V E P F L + RG
Sbjct: 480 DVGSD-------------SCSTEIVIKEP------------PSFIKTLEPADIVRGTNAL 514
Query: 2832 LQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTC 2885
LQ E+ G P + W ++ + + + R+F ++ L L + + G Y C
Sbjct: 515 LQCEVSGTGPFEISWFKDKKQIRS-SKKYRLFSQKSLVCLEIFSFNSADVGEYEC 568
Score = 101 bits (243), Expect = 3e-20
Identities = 96/370 (25%), Positives = 151/370 (40%), Gaps = 55/370 (14%)
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTI 3111
F DI P + ++AGE+A+ C V G + W K+ E+ G T G L I
Sbjct: 2937 FFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRP-GGNYTITCVGNTPHLRI 2995
Query: 3112 KDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFT 3171
+ D G+Y+C+ATN GK A+L+V +E PP+F
Sbjct: 2996 LKVGKGDSGQYTCQATNDVGKDMCSAQLSV--------------KE---------PPKFV 3032
Query: 3172 MRLRDRRV-QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPT 3230
+L +V + ++L C++ GSP KVSW+++ E+ + N L I
Sbjct: 3033 KKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEA 3092
Query: 3231 NLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAV 3290
+ +D G Y A N G SC L V P F P+ L +G ++ +
Sbjct: 3093 SAEDSGDYICEAHNGVGDASCSTALTVK------APPVFTQKPSPVGAL-KGSDVILQCE 3145
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
+ P V W +D ++R S++ +T + L + + D G Y C A+NEVG
Sbjct: 3146 ISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTNLHILNLEASDVGEYHCKATNEVGSD 3204
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ S V+ + + P F++K + GD V + V G
Sbjct: 3205 TCSCSVK----------------------FKEPPRFVKKLSDTSTLIGDAVELRAIVEGF 3242
Query: 3411 PKPDVYWLRD 3420
V WL+D
Sbjct: 3243 QPISVVWLKD 3252
Score = 101 bits (241), Expect = 6e-20
Identities = 100/376 (26%), Positives = 147/376 (39%), Gaps = 52/376 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV P L++L G+ T ++G P V W + E+ + R F L
Sbjct: 2558 PSFVKE-PEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVK-GDRCNIYFEDTVAEL 2615
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ +I+I G Y+C +N G+AS RL V +E P
Sbjct: 2616 ELFNIDISQSGEYTCVVSNNAGQASCTTRLFV--------------KE---------PAA 2652
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F RL D V+ + L G+ P V+W KDG + ++ N E+ LEI
Sbjct: 2653 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILN 2712
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ D G Y N +G CG +V P F LEPL + GD + +
Sbjct: 2713 STKRDAGQYSCEIENEAGRDV--CGALVS----TLEPPYFVTELEPL-EAAVGDSVSLQC 2765
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
V P + V+WY+ +LRP+ T + L V D+G YTC A N +G
Sbjct: 2766 QVAGTPEITVSWYKGDTKLRPTPE-YRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGT 2824
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
AS+ + E ++P P F R+ + E G V + C + G
Sbjct: 2825 ASSKTVFRI------QERQLP-------------PSFARQLKDIEQTVGLPVTLTCRLNG 2865
Query: 3410 DPKPDVYWLRDFLKVR 3425
V W RD + +R
Sbjct: 2866 SAPIQVCWYRDGVLLR 2881
Score = 99.1 bits (236), Expect = 2e-19
Identities = 98/384 (25%), Positives = 151/384 (39%), Gaps = 54/384 (14%)
Query: 3037 TSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG 3096
+ S G + + P FV PG +L G L + +G + W K E+ G
Sbjct: 858 SKDSSGALIVQEPPSFVT-KPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVS-GG 915
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
+ L + + D G Y+C+ +N G A L V +
Sbjct: 916 SCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV--------------K 961
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + VE P Q ++ AT +L C+V G+PP K++W+ + E+ +
Sbjct: 962 EPATFVEKLEPSQLL-----KKGDAT---QLACKVTGTPPIKITWFANDREIKESSKHRM 1013
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
E L + ++D G Y A+N +G S HC +V Y EF +P+
Sbjct: 1014 SFVESTAVLRLTDVGIEDSGEYMCEAQNEAG--SDHCSSIVIVKESPYFTKEF----KPI 1067
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
L E D + + A V P +TW++D LR S R T +D + L + DA
Sbjct: 1068 EVLKEYD-VMLLAEVAGTPPFEITWFKDNTILR-SGRKYKTFIQDHLVSLQILKFVAADA 1125
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G Y C +NEVG + S +V + EP P FI+K S+ +
Sbjct: 1126 GEYQCRVTNEVGSSICSARVTL------REP----------------PSFIKKIESTSSL 1163
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
G T + + G V WL+D
Sbjct: 1164 RGGTAAFQATLKGSLPITVTWLKD 1187
Score = 98.7 bits (235), Expect = 3e-19
Identities = 98/393 (24%), Positives = 159/393 (40%), Gaps = 56/393 (14%)
Query: 3029 YGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG 3088
Y + + S S +G+ + P F+ L + E C + G P V+W K+
Sbjct: 3950 YASNIAGKDSCSAQLGVQ-EPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDE 4008
Query: 3089 HEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVW 3148
E++E + + F L + +++++D G Y+CEA N G AS+ L V
Sbjct: 4009 TEIQESS-KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV------- 4060
Query: 3149 EADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
+ + R++ +E T++ D V L C++ G+PP VSWYKD E+
Sbjct: 4061 -KEPPIFRKKPHPIE-------TLKGAD--------VHLECELQGTPPFHVSWYKDKREL 4104
Query: 3209 VYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP 3267
K + K E F T + I + D G Y+ A N+ G+ +C G + K P
Sbjct: 4105 RSGK-KYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTC-VGSIALK-----APP 4157
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
F L + + G E+++ +E + V W++D + I + L
Sbjct: 4158 RFVKKLSDISTV-VGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 4216
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI 3387
+ V +AG YTC N+ +G E T EP +
Sbjct: 4217 FSRVEPANAGKYTCQIKND------AGMQECFATLSVLEP----------------ATIV 4254
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
KP S + GDT +EC V G P+ W +D
Sbjct: 4255 EKPESIKVTTGDTCTLECTVAGTPELSTKWFKD 4287
Score = 97.9 bits (233), Expect = 6e-19
Identities = 89/314 (28%), Positives = 130/314 (41%), Gaps = 30/314 (9%)
Query: 3045 LAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
L + P FV + L L G+T L +V+G V WMK G EV E G++ F+
Sbjct: 584 LLKEPPTFVKKVD-DLIALGGQTVTLQAAVRGSEPISVTWMK-GQEVIREDGKIKMSFSN 641
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG 3164
L I D+ I G+Y+C A N G ++ L V + AK+ ER+ ++
Sbjct: 642 GVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIV-------KEPAKII-ERAELIQ- 692
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
V A P L V G+P K WYKDG +V K+
Sbjct: 693 --------------VTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQ 738
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
L+ L D G Y N G+ SC V + +AP F L + + G
Sbjct: 739 LKFYSAELHDSGQYTFEISNEVGSSSCETTFTV---LDRDIAPFFTKPLRNVDSVVNG-T 794
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
R+ + + V+W++DG + S R + +G L + V DAG +TC A+
Sbjct: 795 CRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAF-VEGTASLEIIRVDMNDAGNFTCRAT 853
Query: 3345 NEVGRASTSGKVEV 3358
N VG +SG + V
Sbjct: 854 NSVGSKDSSGALIV 867
Score = 97.9 bits (233), Expect = 6e-19
Identities = 105/395 (26%), Positives = 156/395 (39%), Gaps = 58/395 (14%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV 3091
G+SS T+ + V P F L +L G + L C V G V W ++
Sbjct: 2448 GKSSCTAV-VDVSDRAVPPSFTRRLKNTGGVL-GASCILECKVAGSSPISVAWFHEKTKI 2505
Query: 3092 EEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEAD 3151
A T+ F+ C L + ++ D G Y+C A N G A L TV E
Sbjct: 2506 VSGAKYQTT-FSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL------TVQE-- 2556
Query: 3152 AKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD 3211
PP F V V T + G+PP KV+W++ E+V
Sbjct: 2557 ---------------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG 2601
Query: 3212 KRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC 3271
R N Y ++ LE+ ++ G Y NN+G SC L V K A++
Sbjct: 2602 DRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV-KEPAAFLKRLSDH 2660
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRA-IMTLDRDGQIELALAA 3330
+EP G + + + + VTW +DG + S + I+T ++ +E+ +
Sbjct: 2661 SVEP------GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNS- 2713
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
T RDAG Y+C NE GR V T EP P F+ +
Sbjct: 2714 -TKRDAGQYSCEIENEAGRDVCGALV------STLEP----------------PYFVTEL 2750
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
EA GD+V ++C+V G P+ V W + K+R
Sbjct: 2751 EPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 2785
Score = 97.9 bits (233), Expect = 6e-19
Identities = 90/346 (26%), Positives = 138/346 (39%), Gaps = 36/346 (10%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P+FV L GE+ L C + G P V W +N E+ E+ + F L
Sbjct: 3029 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSEL-HESWKYNMSFINSVALL 3087
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
TI + + +D G Y CEA N G AS L V PP
Sbjct: 3088 TINEASAEDSGDYICEAHNGVGDASCSTALTVKA-----------------------PPV 3124
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIA 3228
FT + V L C++ G+PP +V W KD ++ V + ++ K + F T L I
Sbjct: 3125 FTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQ-VRNSKKFKITSKHFDTNLHIL 3183
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
D G Y A N G+ +C C ++ P F L L GD + +
Sbjct: 3184 NLEASDVGEYHCKATNEVGSDTCSC------SVKFKEPPRFVKKLSDTSTL-IGDAVELR 3236
Query: 3289 AVVEAYPSVGVTWYRD-GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
A+VE + + V W +D G +R S ++ D L L + ++G Y C N+
Sbjct: 3237 AIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATLQLGSPEASNSGKYICQIKNDA 3295
Query: 3348 GRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
G S + V+ + E + P+ ++ P++ E + P S
Sbjct: 3296 GMRECSAVLTVLEPARIIE-KPEPMTVTTGNPFALECVVTGTPELS 3340
Score = 97.9 bits (233), Expect = 6e-19
Identities = 96/372 (25%), Positives = 159/372 (42%), Gaps = 39/372 (10%)
Query: 2571 KAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN 2630
KA + +V S + + P F+ L D G V C + S V+WY++
Sbjct: 3758 KADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKD 3817
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
GVLL + + V + TL++L S +Y+C+ N G S+SA L + E
Sbjct: 3818 GVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL-ILSEHE-- 3874
Query: 2691 PIPPTF-TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV 2749
+PP F + + L E+ +C + G KITW KD+++I G Y+ L +
Sbjct: 3875 -VPPFFDLKPVSVDLALGESG-TFKCHVTGTAPIKITWAKDNREIRPGGNYK-MTLVENT 3931
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L + D+G YTC A N G++S S + E R ++ LE
Sbjct: 3932 ATLTVLKVGKGDAGQYTCYAS------------NIAGKDS-CSAQLGVQEPPRFIKK-LE 3977
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYT 2869
R + T Y+ GG+ EI +V W ++ + E + FV+ +
Sbjct: 3978 PSRIVKQDEFTRYECKIGGS----PEI-----KVLWYKDETEIQESSKFRMSFVD-SVAV 4027
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L + +++ +SG YTC A +A G+ + ++ V +P KP P + + G
Sbjct: 4028 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKP-----HPIETL---KGA 4079
Query: 2930 DINISFRTQGEP 2941
D+++ QG P
Sbjct: 4080 DVHLECELQGTP 4091
Score = 97.9 bits (233), Expect = 6e-19
Identities = 91/371 (24%), Positives = 155/371 (41%), Gaps = 46/371 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN-GVLLDNKLKYRKKLVDGLITLE 2652
P F L+D + V G V+L ++ + +V W+++ G ++ + + TL+
Sbjct: 4157 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 4216
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
P+++ +Y+C ++N+ G A L V P + + DT
Sbjct: 4217 FSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDT-------CT 4269
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
LEC + G P WFKD K++ SD +Y+ + + V L I N P DSG Y+ + +N
Sbjct: 4270 LECTVAGTPELSTKWFKDGKELTSDNKYKISFF-NKVSGLKIINVAPSDSGVYSFEVQNP 4328
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
V D T QVS V P F L + G ++ +
Sbjct: 4329 VGKDSCT-------ASLQVSDRTVP---------------PSFTRKLKETNGLSGSSVVM 4366
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ ++ G P V W EG ++ R + + L ++ + E++SG YTC A +
Sbjct: 4367 ECKVYGSPPISVSWFHEGNEISS-GRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 4425
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK-----PKAV 2946
G+ + +A +TV +P KP D+L G ++ + +G P K
Sbjct: 4426 GSDECSAPLTVREPPSFVQKP------DPMDVL--TGTNVTFTSIVKGTPPFSVSWFKGS 4477
Query: 2947 PERIPGEPCVV 2957
E +PG+ C V
Sbjct: 4478 SELVPGDRCNV 4488
Score = 97.5 bits (232), Expect = 7e-19
Identities = 82/327 (25%), Positives = 133/327 (40%), Gaps = 30/327 (9%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK 2637
S S R + P F L AV G C V + V+W ++ + +
Sbjct: 4802 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 4861
Query: 2638 LKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT 2697
KY+ ++ L VL DS +Y+C NE G S +A L + + IPP+FT
Sbjct: 4862 GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI----KERLIPPSFT 4917
Query: 2698 RSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
+ + +T E N LE R+ G + W+K++ +I + + + L +
Sbjct: 4918 KRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTLVLQVRK 4976
Query: 2757 PTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG 2816
D+G YTCK N + T ++V E + P F
Sbjct: 4977 AGMNDAGLYTCKVSNDAGSALCT-------------SSIVIKE---------PKKPPVFD 5014
Query: 2817 NVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDV 2875
LT V+ G + L ++G P R++WL+ GR + R + F G L L DV
Sbjct: 5015 QHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFA-SGTAVLELRDV 5073
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITV 2902
+ +SG Y C+A + G+ + +T+
Sbjct: 5074 AKADSGDYVCKASNVAGSDTTKSKVTI 5100
Score = 97.1 bits (231), Expect = 1e-18
Identities = 91/365 (24%), Positives = 144/365 (39%), Gaps = 53/365 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + + G L C V G P W K+G E+ ++ + N L I +
Sbjct: 3316 PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKV-ASLKIPCAEM 3374
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+G YS E N+ GK++ + V +DR V PP F +L+D
Sbjct: 3375 SDKGLYSFEVKNSVGKSNCTVSVHV-SDRIV-------------------PPSFIRKLKD 3414
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+V GS P V W++DG E+V + E TL ++ D G
Sbjct: 3415 VNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTG 3474
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
+Y A N +G+ C L V + P+ +E L G L ++V+ P
Sbjct: 3475 IYTCVAANVAGSDECSAVLTVQEPPSFEQTPD---SVEVL----PGMSLTFTSVIRGTPP 3527
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
V W++ L P ++L+ D EL L V ++G Y+C +N+ G AS + +
Sbjct: 3528 FKVKWFKGSRELVPGESCNISLE-DFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHL 3586
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEP-MFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
+ KEP F+++ G +++E G P V
Sbjct: 3587 -----------------------FVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISV 3623
Query: 3416 YWLRD 3420
W++D
Sbjct: 3624 SWIKD 3628
Score = 96.7 bits (230), Expect = 1e-18
Identities = 80/303 (26%), Positives = 128/303 (42%), Gaps = 35/303 (11%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+G +L C V + +TW+ N + K+R V+ L + + DS EY C
Sbjct: 978 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMC 1037
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
+NE G+ S+ + V S P FT+ + L E +++L + G P +IT
Sbjct: 1038 EAQNEAGSDHCSSIVIVKES-------PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEIT 1090
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFKD+ + S +Y+ F + D + L I D+G Y C+ N V +
Sbjct: 1091 WFKDNTILRSGRKYKTF-IQDHLVSLQILKFVAADAGEYQCRVTNEVGS----------- 1138
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEW 2845
S S V E P F + RGGT Q ++G P V W
Sbjct: 1139 --SICSARVTLREP------------PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTW 1184
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
L++ +TE N R+ E + +L LS + G Y C+A + G +A ++V +P
Sbjct: 1185 LKDSDEITE-DDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP 1243
Query: 2906 SDL 2908
+ +
Sbjct: 1244 ATI 1246
Score = 96.7 bits (230), Expect = 1e-18
Identities = 92/354 (25%), Positives = 142/354 (40%), Gaps = 50/354 (14%)
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C + G V W K+G ++++A TS + L I + G+Y+C A+N G
Sbjct: 3802 CRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNV-ATLQILQTDQSHIGQYNCSASNPLG 3860
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
AS+ A+L + E + PP F ++ + C V
Sbjct: 3861 TASSSAKLILS--------------------EHEVPPFFDLKPVSVDLALGESGTFKCHV 3900
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G+ P K++W KD E+ E TL + D G Y A N +G SC
Sbjct: 3901 TGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSC 3960
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
L V + P F LEP + + + R + P + V WY+D ++ S
Sbjct: 3961 SAQLGVQE------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQES 4014
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
+ M+ D L + ++ D+G YTC A N G AS+S ++V EP
Sbjct: 4015 SKFRMSFV-DSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV------KEP---- 4063
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
P+F +KP E +G V +ECE+ G P V W +D ++R
Sbjct: 4064 ------------PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELR 4105
Score = 96.3 bits (229), Expect = 2e-18
Identities = 90/376 (23%), Positives = 147/376 (39%), Gaps = 54/376 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F L ++ + G +L C V G + W K+ E+ + F+ L
Sbjct: 1340 PSFTKKLK-KMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASE-KYKFSFHDNTAFL 1397
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I + D G Y+C ATN G L V +E PP
Sbjct: 1398 EISQLEGTDSGTYTCSATNKAGHNQCSGHLTV--------------KE---------PPY 1434
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F + + + V V+L V G+ P + W+KD +E+ R+ ++D+ +LE+
Sbjct: 1435 FVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFA 1494
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
D G Y N+ G + L V + P+F P+ L G
Sbjct: 1495 AKATDSGTYICQLSNDVGTATSKATLFVKE------PPQFIKKPSPVLVLRNGQSTTFEC 1548
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
+ P + V+WY DG + ++ ++ DG ++ ++G Y C A N+ G
Sbjct: 1549 QITGTPKIRVSWYLDGNEITAIQKHGISF-IDGLATFQISGARVENSGTYVCEARNDAGT 1607
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
AS S +++V EP P FIR+ + E + V +ECEV G
Sbjct: 1608 ASCSIELKV------KEP----------------PTFIRELKPVEVVKYSDVELECEVTG 1645
Query: 3410 DPKPDVYWLRDFLKVR 3425
P +V WL++ ++R
Sbjct: 1646 TPPFEVTWLKNNREIR 1661
Score = 95.9 bits (228), Expect = 2e-18
Identities = 81/309 (26%), Positives = 128/309 (41%), Gaps = 35/309 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P F D+ P + + GE+ C V G + W K+ E+ +MT N
Sbjct: 3876 PPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN--TAT 3933
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
LT+ + D G+Y+C A+N GK S A+L V PP
Sbjct: 3934 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGV-----------------------QEPP 3970
Query: 3169 QFTMRLRDRR-VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
+F +L R V+ R C++ GSP KV WYKD E+ + + LE+
Sbjct: 3971 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 4030
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+++D G Y A N +G+ S L V + P F P+ L +G ++ +
Sbjct: 4031 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE------PPIFRKKPHPIETL-KGADVHL 4083
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
++ P V+WY+D LR S + + + + + V D G Y C A+N+V
Sbjct: 4084 ECELQGTPPFHVSWYKDKRELR-SGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 4142
Query: 3348 GRASTSGKV 3356
G + G +
Sbjct: 4143 GSDTCVGSI 4151
Score = 95.5 bits (227), Expect = 3e-18
Identities = 77/307 (25%), Positives = 128/307 (41%), Gaps = 32/307 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L+D + G + L + + +VTW ++G + K + LE+LN+
Sbjct: 2657 LSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKR 2716
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ +YSC +ENE G V + ++ PP F + + + L+C++ G
Sbjct: 2717 DAGQYSCEIENEAGR-------DVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAG 2769
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P ++W+K D ++ Y+ Y + V L + DSG YTCKAENS+ T
Sbjct: 2770 TPEITVSWYKGDTKLRPTPEYRT-YFTNNVATLVFNKVNINDSGEYTCKAENSIGT---- 2824
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
S V RI + L P F L D + G + L + G
Sbjct: 2825 -----------ASSKTV----FRIQERQLP---PSFARQLKDIEQTVGLPVTLTCRLNGS 2866
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P +V W R+G + + + N + + TL + + SG Y+C A + G +A
Sbjct: 2867 APIQVCWYRDGVLLRD-HENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA 2925
Query: 2899 AITVVQP 2905
+T +P
Sbjct: 2926 RLTAREP 2932
Score = 95.5 bits (227), Expect = 3e-18
Identities = 173/796 (21%), Positives = 294/796 (36%), Gaps = 85/796 (10%)
Query: 2608 GSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G+ V T S++ + P +V+W++ L + L D + LE+ + S S EY+C
Sbjct: 4454 GTNVTFT-SIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTC 4512
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
V NE G S + +L + P F + + D L+LE G P +T
Sbjct: 4513 IVSNEAGKASCTTHLYI-------KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 4565
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W K+ + R L I + T ED+G Y C EN+ +G
Sbjct: 4566 WKKNGINVTPSQRCNITTTEKSPI-LEIPSSTVEDAGQYNCYIENA------------SG 4612
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEW 2845
++S + Q L P+F L +V+ G + LQ ++ G P V W
Sbjct: 4613 KDS-------------CSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW 4659
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ- 2904
+ G + ++ + TL + V +SG Y C+A ++ G V + +TV +
Sbjct: 4660 YK-GDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 4718
Query: 2905 --PSDLDGKPAVI---VGRPEK-DILISVGEDINISFRTQGEPKPKA--VPERIPGEPCV 2956
P + + VG P D IS E I++S+ G+P + V
Sbjct: 4719 KLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT 4778
Query: 2957 VDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEG-GARWVELGITPLNSFDAFNLKQ 3015
++ SLA S T P+ + + LI EG + ++ + P+++
Sbjct: 4779 LNIFKTDRSLAGQYSCTATN-PIGSASSSARLILTEGKNPPFFDIRLAPVDA--VVGESA 4835
Query: 3016 GEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC--- 3072
E H T + W + S+ S G + LK+ G++ TC
Sbjct: 4836 DFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLT--VLKVDKGDSGQYTCYAV 4893
Query: 3073 ------------SVKGKPVPGVVWMKNGHEVEEEAG---RMTSQFNGFD-CCLTIKDINI 3116
++K + +P + VEE G ++ + G + NI
Sbjct: 4894 NEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNI 4953
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVW------EADAKLKRERSAEVEGDYPPQF 3170
+ + +CE T + R A + D ++ +A + L E PP F
Sbjct: 4954 EIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 5013
Query: 3171 TMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPT 3230
L V V+L+C V GS P ++ W K G E+ R + LE+
Sbjct: 5014 DQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDV 5073
Query: 3231 NLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI--- 3287
D G Y A N +G+ + + + A + L+ + E +R+
Sbjct: 5074 AKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEK 5133
Query: 3288 -----SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
A V P V W + R + + + +L + T D+G+Y C
Sbjct: 5134 TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCV 5193
Query: 3343 ASNEVGRASTSGKVEV 3358
A NE G ++ ++V
Sbjct: 5194 AFNEHGEIESNVNLQV 5209
Score = 95.5 bits (227), Expect = 3e-18
Identities = 82/314 (26%), Positives = 138/314 (43%), Gaps = 23/314 (7%)
Query: 2594 PVFSTFLTDRTA-VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F+ L++ EG+ KL V S TV WY+N + + + + L+
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQ 4973
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
V A +D+ Y+C V N+ G+ ++++ + + PP F + + ++E E V
Sbjct: 4974 VRKAGMNDAGLYTCKVSNDAGSALCTSSIVI----KEPKKPPVFDQHLTPV-TVSEGEYV 5028
Query: 2713 -LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G +I W K ++I R +F A G L + + DSG Y CKA N
Sbjct: 5029 QLSCHVQGSEPIRIQWLKAGREIKPSDRC-SFSFASGTAVLELRDVAKADSGDYVCKASN 5087
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
+D V + P V A K ++ R F + +V T
Sbjct: 5088 VAGSDTTKSKVTIKDK-----PAVAPATK-----KAAVDGRLFFVSEPQSIRVVEKTTAT 5137
Query: 2832 LQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQ--GLYTLALSDVTETESGLYTCRAW 2888
++ G P V+W + G+ ++ + RVF+ Q L + D T+T+SGLY C A+
Sbjct: 5138 FIAKVGGDPIPNVKWTK-GK-WRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAF 5195
Query: 2889 SAHGNVDMNAAITV 2902
+ HG ++ N + V
Sbjct: 5196 NEHGEIESNVNLQV 5209
Score = 95.1 bits (226), Expect = 4e-18
Identities = 87/353 (24%), Positives = 151/353 (42%), Gaps = 31/353 (8%)
Query: 2565 DMRHRSKAFSEARSVISEKRTLSRNSTRKPVFSTF-LTDRTAVEGSRVKLTCSVISSSDP 2623
+++H K +A++ +R + S ++P T +G L + +
Sbjct: 1214 EVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEI 1273
Query: 2624 TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
T W+++G L KY+ + D + L++++ DS EY+ V+N+ G S A + V
Sbjct: 1274 TAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINV 1333
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
IPP+FT+ ++ + + + LEC + G I WFKDD++I + +Y+ F
Sbjct: 1334 LDLI----IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYK-F 1388
Query: 2744 YLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRI 2803
D L I DSGTYTC A N +Q + + T +E P V EK
Sbjct: 1389 SFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSG--HLTVKE---PPYFV--EKP-- 1439
Query: 2804 ARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFV 2863
QS + P N + GGT P ++W ++ + + + V+
Sbjct: 1440 --QS-QDVNP---NTRVQLKALVGGT---------APMTIKWFKDNKELHSGAARS-VWK 1483
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIV 2916
+ +L L T+SG Y C+ + G A + V +P KP+ ++
Sbjct: 1484 DDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVL 1536
Score = 94.7 bits (225), Expect = 5e-18
Identities = 87/353 (24%), Positives = 140/353 (39%), Gaps = 38/353 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F T L A G V L C V + + TV+WY+ L +YR + + TL V
Sbjct: 2744 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL-V 2802
Query: 2654 LNAVP-SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
N V +DS EY+C EN G S+ ++ + +PP+F R ++D +
Sbjct: 2803 FNKVNINDSGEYTCKAENSIGTASSKTVFRI----QERQLPPSFARQLKDIEQTVGLPVT 2858
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L CR+ G ++ W++D + Q ++ D V L I SG Y+C A N
Sbjct: 2859 LTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFV-DNVATLKILQTDLSHSGQYSCSASNP 2917
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ T + T RE + S P F V G +
Sbjct: 2918 LGT--ASSSARLTAREPKKS--------------------PFFDIKPVSIDVIAGESADF 2955
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P R+ W ++ + + N + L + V + +SG YTC+A +
Sbjct: 2956 ECHVTGAQPMRITWSKDNKEI-RPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDV 3014
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
G +A ++V +P V + E + GE I + + G P+ K
Sbjct: 3015 GKDMCSAQLSVKEPPK-------FVKKLEASKVAKQGESIQLECKISGSPEIK 3060
Score = 94.3 bits (224), Expect = 7e-18
Identities = 97/385 (25%), Positives = 151/385 (39%), Gaps = 56/385 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-R 3097
+S L P P + L G L C + G P VVW+K+ +V +
Sbjct: 3111 ASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFK 3170
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+TS+ FD L I ++ D G Y C+ATN G +
Sbjct: 3171 ITSKH--FDTNLHILNLEASDVGEYHCKATNEVGSDTC---------------------- 3206
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
S V+ PP+F +L D V L V G P V W KD EV+ + +
Sbjct: 3207 -SCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRI 3265
Query: 3218 Q-DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
+ TL++ + G Y +N++G C L V + R P EP+
Sbjct: 3266 SFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP------EPM 3319
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQIELALAAVTTRD 3335
+ G+ + VV P + W++DG L S+ I +++ +++ A ++ D
Sbjct: 3320 -TVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMS--D 3376
Query: 3336 AGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA 3395
G+Y+ N VG+++ + V V RI P P FIRK + A
Sbjct: 3377 KGLYSFEVKNSVGKSNCTVSVHV-------SDRIVP------------PSFIRKLKDVNA 3417
Query: 3396 REGDTVIIECEVVGDPKPDVYWLRD 3420
G +V++EC V G V W +D
Sbjct: 3418 ILGASVVLECRVSGSAPISVGWFQD 3442
Score = 93.9 bits (223), Expect = 9e-18
Identities = 93/354 (26%), Positives = 143/354 (40%), Gaps = 43/354 (12%)
Query: 2591 TRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
T P F L V+ G +L C + S + V W+RN L KYR +D +
Sbjct: 2085 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 2144
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+++ N DS ++ C +N G+ S S + V S PP I +T L
Sbjct: 2145 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPP-----IVET--LKNA 2197
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
E+ LEC + G P ++ W+KD +Q+ S +Y+ + + I N D G Y CKA
Sbjct: 2198 EVSLECELSGTPPFEVVWYKDKRQLRSSKKYK-IASKNFHTSIHILNVDTSDIGEYHCKA 2256
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
+ N G S V K + P F + L V G
Sbjct: 2257 Q------------NEVG-----SDTCVCTVKLK--------EPPRFVSKLNSLTVVAGEP 2291
Query: 2830 IGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAW 2888
LQ I G P V+WL+E V N R+ + + TL + +G Y C+
Sbjct: 2292 AELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIK 2351
Query: 2889 SAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
+ G + A + V++ PAVIV + + ++VGE + + G P+
Sbjct: 2352 NDGGMRENMATLMVLE-------PAVIVEK-AGPMTVTVGETCTLECKVAGTPE 2397
Score = 93.5 bits (222), Expect = 1e-17
Identities = 93/361 (25%), Positives = 142/361 (39%), Gaps = 50/361 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G LTC + G V W ++G + + TS + L I ++ G+YSC
Sbjct: 2854 GLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNV-ATLKILQTDLSHSGQYSC 2912
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A+N G AS+ ARL RE P F ++ V A
Sbjct: 2913 SASNPLGTASSSARLTA--------------REPKKS------PFFDIKPVSIDVIAGES 2952
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
C V G+ P +++W KD +E+ L I D G Y A N
Sbjct: 2953 ADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATN 3012
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
+ G C L V + P+F LE +G+ +++ + P + V+W+R+
Sbjct: 3013 DVGKDMCSAQLSVKE------PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRN 3066
Query: 3305 GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQT 3364
L S + M+ + L + + D+G Y C A N VG AS S + V
Sbjct: 3067 DSELHESWKYNMSFINSVAL-LTINEASAEDSGDYICEAHNGVGDASCSTALTV------ 3119
Query: 3365 SEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+ PPV F +KP A +G VI++CE+ G P +V W++D +V
Sbjct: 3120 ---KAPPV-------------FTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQV 3163
Query: 3425 R 3425
R
Sbjct: 3164 R 3164
Score = 91.5 bits (217), Expect = 5e-17
Identities = 88/364 (24%), Positives = 151/364 (41%), Gaps = 36/364 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN-GVLLDNKLKYRKKLVDGLITLE 2652
P F L+D + + G V+L V +V W ++ G ++ R +D + TL+
Sbjct: 3216 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ 3275
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + S+S +Y C ++N+ G SA L V P T + + F
Sbjct: 3276 LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPF-------A 3328
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
LEC + G P WFKD +++ +D ++ ++ + V L I D G Y+ + +NS
Sbjct: 3329 LECVVTGTPELSAKWFKDGRELSADSKHHITFI-NKVASLKIPCAEMSDKGLYSFEVKNS 3387
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
V T V+ VS +V P F L D G ++ L
Sbjct: 3388 VGKSNCTVSVH-------VSDRIVP---------------PSFIRKLKDVNAILGASVVL 3425
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P V W ++G + + F E + TL LS + +++G+YTC A +
Sbjct: 3426 ECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCTLNLSLLEPSDTGIYTCVAANVA 3484
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIP 2951
G+ + +A +TV +P + P + P + + F+ + K E +P
Sbjct: 3485 GSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWF---KGSRELVP 3541
Query: 2952 GEPC 2955
GE C
Sbjct: 3542 GESC 3545
Score = 91.5 bits (217), Expect = 5e-17
Identities = 73/304 (24%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G+ L C V + + + W+++G L K+ ++ + +L++ A SD
Sbjct: 3320 TVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGL 3379
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
YS V+N G + + ++ V +PP+F R ++D + +VLECR+ G
Sbjct: 3380 YSFEVKNSVGKSNCTVSVHVSDRI----VPPSFIRKLKDVNAILGASVVLECRVSGSAPI 3435
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ WF+D +I S + Q+ + ++ VC L + P D+G YTC A N +D+ +
Sbjct: 3436 SVGWFQDGNEIVSGPKCQSSF-SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECS---- 3490
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
V+T ++ P F +V G ++ IRG P +
Sbjct: 3491 ----------AVLTVQEP-----------PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFK 3529
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+W + R + + + +E + L L +V ESG Y+C + G+ + V
Sbjct: 3530 VKWFKGSRELVP-GESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 3588
Query: 2903 VQPS 2906
+P+
Sbjct: 3589 KEPA 3592
Score = 91.5 bits (217), Expect = 5e-17
Identities = 76/312 (24%), Positives = 127/312 (40%), Gaps = 27/312 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L AV G L C V + + ++WY+ L + Y+ + + + +L +
Sbjct: 3685 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 3744
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
SD EYSC +N GA+++SA L + +A +PP F R ++D +
Sbjct: 3745 NKVDHSDVGEYSCKADNSVGAVASSAVLVI----KARKLPPFFARKLKDVHETLGFPVAF 3800
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
ECRI G +++W+KD + D Q ++ V L I G Y C A N +
Sbjct: 3801 ECRINGSEPLQVSWYKDGVLLKDDANLQTSFV-HNVATLQILQTDQSHIGQYNCSASNPL 3859
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
T + E +V P +P V D + GT
Sbjct: 3860 GT--ASSSAKLILSEHEVPP--------------FFDLKP----VSVDLALGESGTFKCH 3899
Query: 2834 VEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
V P ++ W ++ R + N ++ + + TL + V + ++G YTC A + G
Sbjct: 3900 V-TGTAPIKITWAKDNREI-RPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 3957
Query: 2894 VDMNAAITVVQP 2905
+A + V +P
Sbjct: 3958 DSCSAQLGVQEP 3969
Score = 91.1 bits (216), Expect = 6e-17
Identities = 90/384 (23%), Positives = 146/384 (38%), Gaps = 52/384 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
S+S L P P ++ L G +L C ++G P V W K+ E+ +
Sbjct: 4051 SASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRS-GKK 4109
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
F + I +++ D G Y C+ATN G + +A+
Sbjct: 4110 YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA-------------- 4155
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
PP+F +L D V+L + G+ P V W+KD E+V +
Sbjct: 4156 ---------PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWI 4206
Query: 3218 Q-DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
E TL+ + + G Y +N++G C L V + PE
Sbjct: 4207 SYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESI------ 4260
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
K+ GD + V P + W++DG L + ++ L + V D+
Sbjct: 4261 -KVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 4318
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
GVY+ N VG+ S + ++V +D+T VP P F RK + +
Sbjct: 4319 GVYSFEVQNPVGKDSCTASLQV--SDRT-------------VP----PSFTRKLKETNGL 4359
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
G +V++EC+V G P V W +
Sbjct: 4360 SGSSVVMECKVYGSPPISVSWFHE 4383
Score = 89.8 bits (213), Expect = 1e-16
Identities = 92/373 (24%), Positives = 144/373 (38%), Gaps = 57/373 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV L + + G+ L +++G VVW K+ E+ E+ + ++ L
Sbjct: 4157 PRFVKKL-SDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATL 4215
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ + G+Y+C+ N G +A L+V+ T+ E +K GD
Sbjct: 4216 QFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIK-----VTTGD---- 4266
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT---LE 3226
L C V G+P W+KDG+E+ D NKY+ F+ L+
Sbjct: 4267 --------------TCTLECTVAGTPELSTKWFKDGKELTSD---NKYKISFFNKVSGLK 4309
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I D GVY +N G SC L V V P F L+ L G +
Sbjct: 4310 IINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT---VPPSFTRKLKETNGL-SGSSVV 4365
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ V P + V+W+ +G + R+ TL D L + + D+G YTC A+N
Sbjct: 4366 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLT-DNTCALTVNMLEESDSGDYTCIATN- 4423
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
+ G+D+ S P + + P F++KP + G V
Sbjct: 4424 -----------MAGSDECSAP----------LTVREPPSFVQKPDPMDVLTGTNVTFTSI 4462
Query: 3407 VVGDPKPDVYWLR 3419
V G P V W +
Sbjct: 4463 VKGTPPFSVSWFK 4475
Score = 88.2 bits (209), Expect = 5e-16
Identities = 75/311 (24%), Positives = 129/311 (41%), Gaps = 35/311 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L V+ S V+L C V + VTW +N + + KY + L +
Sbjct: 1620 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 1679
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
PSD+ EY C V NE G+ S S + A PP+F + I +T + ++
Sbjct: 1680 TKCDPSDTGEYQCIVSNEGGSCSCSTRV-------ALKEPPSFIKKIENTTTVLKSSATF 1732
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ + G P ITW KDD+ + D ++ D V L I + SG YTC+A+N
Sbjct: 1733 QSTVAGSPPISITWLKDDQILDEDDNVYISFV-DSVATLQIRSVDNGHSGRYTCQAKNES 1791
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
++ F ++ E +I ++ V + L+
Sbjct: 1792 GVERCYAF-------------LLVQEPAQIVEKA------------KSVDVTEKDPMTLE 1826
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G P +V+WL++G+ + R + E + + + V + +SG YT + + G
Sbjct: 1827 CVVAGTPELKVKWLKDGKQIVP-SRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFG 1885
Query: 2893 NVDMNAAITVV 2903
+ +A + V+
Sbjct: 1886 SSSCDAYLRVL 1896
Score = 87.8 bits (208), Expect = 6e-16
Identities = 75/308 (24%), Positives = 120/308 (38%), Gaps = 34/308 (11%)
Query: 3052 FVDIL-PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
FV+ L P QL + G+ L C V G P + W N E++E + S F L
Sbjct: 966 FVEKLEPSQL-LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMS-FVESTAVLR 1023
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ D+ I+D G Y CEA N G S + V+ + P F
Sbjct: 1024 LTDVGIEDSGEYMCEAQNEAG--SDHCSSIVIVKES---------------------PYF 1060
Query: 3171 TMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPT 3230
T + V Y V L +V G+PP +++W+KD + ++ + + +L+I
Sbjct: 1061 TKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKF 1120
Query: 3231 NLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAV 3290
D G Y+ N G+ C + + + P F +E L G A
Sbjct: 1121 VAADAGEYQCRVTNEVGSSICSARVTLRE------PPSFIKKIESTSSL-RGGTAAFQAT 1173
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
++ + VTW +D + MT + + L L+ + + G Y C A N+ G
Sbjct: 1174 LKGSLPITVTWLKDSDEITEDDNIRMTFE-NNVASLYLSGIEVKHDGKYVCQAKNDAGIQ 1232
Query: 3351 STSGKVEV 3358
S + V
Sbjct: 1233 RCSALLSV 1240
Score = 87.4 bits (207), Expect = 8e-16
Identities = 86/340 (25%), Positives = 138/340 (40%), Gaps = 45/340 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + S VTW++N L R V+ L++ + DS YSC
Sbjct: 417 GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCE 476
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N+ G+ S S + + PP+F +++ + +L+C + G +I+W
Sbjct: 477 AVNDVGSDSCSTEIVIKE-------PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISW 529
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
FKD KQI S +Y+ F VC L I + D G Y C N V G+
Sbjct: 530 FKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYECVVANEV------------GK 576
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWL 2846
++ +++ T F + D G T+ LQ +RG P V W+
Sbjct: 577 CGCMATHLLKEPPT-------------FVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 623
Query: 2847 REGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPS 2906
+ G+ V ++ G+ L + DV + G YTC A + G+ + V +
Sbjct: 624 K-GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE-- 680
Query: 2907 DLDGKPAVIVGRPEKDILISVGEDINISFRTQGEP--KPK 2944
PA I+ R E I ++ G+ + + G P KPK
Sbjct: 681 -----PAKIIERAEL-IQVTAGDPATLEYTVAGTPELKPK 714
Score = 87.0 bits (206), Expect = 1e-15
Identities = 84/312 (26%), Positives = 132/312 (42%), Gaps = 44/312 (14%)
Query: 3048 DRPEFVDILPG---QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
++P+ D+ P QLK L G TA +T + W K+ E+ A R + +
Sbjct: 1437 EKPQSQDVNPNTRVQLKALVGGTAPMT----------IKWFKDNKELHSGAARSVWK-DD 1485
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG 3164
L + D G Y C+ +N G A++ A L V E +K+
Sbjct: 1486 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK------EPPQFIKK-------- 1531
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
P + LR+ Q+T CQ+ G+P +VSWY DG E+ ++ + T
Sbjct: 1532 ---PSPVLVLRNG--QST---TFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 1583
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
+I+ +++ G Y ARN++G SC L V + P F L+P+ + D
Sbjct: 1584 FQISGARVENSGTYVCEARNDAGTASCSIELKVKE------PPTFIRELKPVEVVKYSD- 1636
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + V P VTW ++ +R S++ +T DR L + D G Y C S
Sbjct: 1637 VELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DRVSVFNLHITKCDPSDTGEYQCIVS 1695
Query: 3345 NEVGRASTSGKV 3356
NE G S S +V
Sbjct: 1696 NEGGSCSCSTRV 1707
Score = 87.0 bits (206), Expect = 1e-15
Identities = 89/384 (23%), Positives = 140/384 (36%), Gaps = 54/384 (14%)
Query: 3037 TSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG 3096
T++S + P+F+ L + G++ C + G P V W +G+E+
Sbjct: 1513 TATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQK 1572
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
S +G I +++ G Y CEA N G AS
Sbjct: 1573 HGISFIDGL-ATFQISGARVENSGTYVCEARNDAGTASC--------------------- 1610
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
S E++ PP F L+ V V L C+V G+PP +V+W K+ E+ K+
Sbjct: 1611 --SIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL 1668
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D G Y+ N G+ SC + + + P F +E
Sbjct: 1669 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE------PPSFIKKIENT 1722
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ + + V P + +TW +D L ++ D L + +V +
Sbjct: 1723 TTVLK-SSATFQSTVAGSPPISITWLKDDQILDEDDNVYISF-VDSVATLQIRSVDNGHS 1780
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G YTC A NE SG EP + K +S +
Sbjct: 1781 GRYTCQAKNE------SGVERCYAFLLVQEP----------------AQIVEKAKSVDVT 1818
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
E D + +EC V G P+ V WL+D
Sbjct: 1819 EKDPMTLECVVAGTPELKVKWLKD 1842
Score = 86.6 bits (205), Expect = 1e-15
Identities = 77/316 (24%), Positives = 138/316 (43%), Gaps = 40/316 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKY-RKKLVDGLITL 2651
P F T + + GS V L + S+ T+ W++ N L+ Y K+ ++ +L
Sbjct: 871 PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALES--SL 928
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
E+ SDS Y+C V N G + SANL V P TF + + L + +
Sbjct: 929 ELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE-------PATFVEKLEPSQLLKKGDA 981
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C++ G P KITWF +D++I +++ ++ + L + + EDSG Y C+A+
Sbjct: 982 TQLACKVTGTPPIKITWFANDREIKESSKHRMSFV-ESTAVLRLTDVGIEDSGEYMCEAQ 1040
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N +D + V I ++S P+F +V + +
Sbjct: 1041 NEAGSDHCSSIV--------------------IVKES-----PYFTKEFKPIEVLKEYDV 1075
Query: 2831 GLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L E+ G P + W ++ ++ R + F++ L +L + ++G Y CR +
Sbjct: 1076 MLLAEVAGTPPFEITWFKD-NTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTN 1134
Query: 2890 AHGNVDMNAAITVVQP 2905
G+ +A +T+ +P
Sbjct: 1135 EVGSSICSARVTLREP 1150
Score = 86.6 bits (205), Expect = 1e-15
Identities = 82/333 (24%), Positives = 141/333 (42%), Gaps = 35/333 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLE 2652
P F + L T V G +L S+ + V W + ++ R V+ + TL+
Sbjct: 2275 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQ 2334
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENEL 2711
A P+++ +Y C ++N+ G A L V P+ P T ++ +T
Sbjct: 2335 FAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGP-MTVTVGET-------C 2386
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC++ G P + W+KD K + S +++ F + + L I + +D+GTYT + +N
Sbjct: 2387 TLECKVAGTPELSVEWYKDGKLLTSSQKHK-FSFYNKISSLRILSVERQDAGTYTFQVQN 2445
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
+V T V+ VS V TR R + G VL G +
Sbjct: 2446 NVGKSSCTAVVD-------VSDRAVPPSFTR--------RLKNTGGVL-------GASCI 2483
Query: 2832 LQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ ++ G P V W E + + F + TL L+ + ++ G YTC A +
Sbjct: 2484 LECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCTLQLNSLDSSDMGNYTCVAANV 2542
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G+ + A +TV +P +P + P K++
Sbjct: 2543 AGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNV 2575
Score = 86.6 bits (205), Expect = 1e-15
Identities = 90/363 (24%), Positives = 139/363 (38%), Gaps = 52/363 (14%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEV--EEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
G++ L + G V W K+G + E+ +T++ C L I + D G+Y
Sbjct: 2665 GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKT---CILEILNSTKRDAGQY 2721
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
SCE N G+ A ++ + PP F L
Sbjct: 2722 SCEIENEAGRDVCGALVSTLE-----------------------PPYFVTELEPLEAAVG 2758
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
V L CQV G+P VSWYK ++ Y TL N++D G Y A
Sbjct: 2759 DSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 2818
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
N+ G S + + + P F L+ + + G + ++ + + V WY
Sbjct: 2819 ENSIGTASSKTVFRIQE---RQLPPSFARQLKDIEQT-VGLPVTLTCRLNGSAPIQVCWY 2874
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
RDGV LR + T D L + +G Y+C+ASN +G AS+S ++
Sbjct: 2875 RDGVLLR-DHENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL------ 2927
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
EP+ K P F KP S + G++ EC V G + W +D
Sbjct: 2928 TAREPK-------------KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNK 2974
Query: 3423 KVR 3425
++R
Sbjct: 2975 EIR 2977
Score = 86.2 bits (204), Expect = 2e-15
Identities = 83/339 (24%), Positives = 145/339 (42%), Gaps = 41/339 (12%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L +V + + WY++G L KYR + + L+ +A DS +Y+
Sbjct: 696 GDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFE 755
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
+ NE G+ S V I P FT+ +R+ + L+C+I G +++W
Sbjct: 756 ISNEVGSSSCETTFTVLDR----DIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSW 811
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
FKD K+I + RY+ ++ +G L I D+G +TC+A NSV + + +
Sbjct: 812 FKDGKEIAASDRYRIAFV-EGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV--- 867
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWL 2846
Q P+ VT +P +VL G + L+ +G P + W
Sbjct: 868 --QEPPSFVT--------------KPGSKDVLP------GSAVCLKSTFQGSTPLTIRWF 905
Query: 2847 REGRSVTEVYRNARVFVEQGL-YTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ + + V + ++ L +L L V ++SG YTC+ + G V+ +A + V +
Sbjct: 906 KGNKEL--VSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE- 962
Query: 2906 SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
PA V + E L+ G+ ++ + G P K
Sbjct: 963 ------PATFVEKLEPSQLLKKGDATQLACKVTGTPPIK 995
Score = 85.4 bits (202), Expect = 3e-15
Identities = 91/374 (24%), Positives = 146/374 (39%), Gaps = 58/374 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P F+ L ++++ L C V G P V W+KN E+ +T + + F+
Sbjct: 1620 PTFIRELK-PVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLH 1678
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
+T D + D G Y C +N G S R+A LK PP
Sbjct: 1679 ITKCDPS--DTGEYQCIVSNEGGSCSCSTRVA-------------LKE----------PP 1713
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD--EQFHTLE 3226
F ++ + V GSPP ++W KD + + D+ N Y + TL+
Sbjct: 1714 SFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ--ILDEDDNVYISFVDSVATLQ 1771
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I + G Y A+N SG C+ L+V + P + E D +
Sbjct: 1772 IRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE-------PAQIVEKAKSVDVTEKDPMT 1824
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ VV P + V W +DG ++ PSR M+ + + + +V +D+G YT N+
Sbjct: 1825 LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFE-NNVASFRIQSVMKQDSGQYTFKVEND 1883
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
G +S + V+ DQ IP P F +K + G ++ +EC+
Sbjct: 1884 FGSSSCDAYLRVL--DQ----NIP-------------PSFTKKLTKMDKVLGSSIHMECK 1924
Query: 3407 VVGDPKPDVYWLRD 3420
V G W +D
Sbjct: 1925 VSGSLPISAQWFKD 1938
Score = 85.0 bits (201), Expect = 4e-15
Identities = 91/378 (24%), Positives = 144/378 (38%), Gaps = 55/378 (14%)
Query: 3045 LAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
L P + P +++L G + T ++G P V W K E+ S
Sbjct: 3493 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNIS-LED 3551
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG 3164
F L + ++ + G YSC TN G AS L V +E
Sbjct: 3552 FVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV--------------KE------- 3590
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
P F RL D V+ P+ L G+PP VSW KD + +R + E+
Sbjct: 3591 --PATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI 3648
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--G 3282
LEI + ++D Y N +G C + + + + P + +EPL + G
Sbjct: 3649 LEILESTIEDYAQYSCLIENEAGQDIC-------EALVSVLEPPYF--IEPLEHVEAVIG 3699
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
+ + V+ P + ++WY++ +LR S A ++ L + V D G Y+C
Sbjct: 3700 EPATLQCKVDGTPEIRISWYKEHTKLR-SAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 3758
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVI 3402
A N VG ++S + V+ + +P P F RK + G V
Sbjct: 3759 ADNSVGAVASSAVL---------------VIKARKLP----PFFARKLKDVHETLGFPVA 3799
Query: 3403 IECEVVGDPKPDVYWLRD 3420
EC + G V W +D
Sbjct: 3800 FECRINGSEPLQVSWYKD 3817
Score = 84.6 bits (200), Expect = 6e-15
Identities = 82/318 (25%), Positives = 128/318 (40%), Gaps = 40/318 (12%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G C + + V+WY +G + K+ +DGL T ++ A +S Y C
Sbjct: 1541 GQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCE 1600
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N+ G S S LKV PPTF R ++ + +++ LEC + G P ++TW
Sbjct: 1601 ARNDAGTASCSIELKVKE-------PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTW 1653
Query: 2728 FKDDKQIPSDGRYQAFYLAD--GVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
K++++I S +Y L D V L I P D+G Y C N
Sbjct: 1654 LKNNREIRSSKKYT---LTDRVSVFNLHITKCDPSDTGEYQCIVSNE------------- 1697
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVE 2844
G S TR+A + P F + + + Q + G P +
Sbjct: 1698 GGSCSCS--------TRVALK----EPPSFIKKIENTTTVLKSSATFQSTVAGSPPISIT 1745
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++ + + E N + + TL + V SG YTC+A + G A + V +
Sbjct: 1746 WLKDDQILDE-DDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE 1804
Query: 2905 PSDLDGKPAVIVGRPEKD 2922
P+ + K A V EKD
Sbjct: 1805 PAQIVEK-AKSVDVTEKD 1821
Score = 84.2 bits (199), Expect = 7e-15
Identities = 79/327 (24%), Positives = 127/327 (38%), Gaps = 33/327 (10%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
E S S V L + P F+ + +L +A +V G P + W+K+ ++
Sbjct: 1697 EGGSCSCSTRVALK-EPPSFIKKIENTTTVLKS-SATFQSTVAGSPPISITWLKDDQILD 1754
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
E+ S F L I+ ++ GRY+C+A N G YA L V
Sbjct: 1755 EDDNVYIS-FVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLV----------- 1802
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
P Q + + V P+ L C V G+P KV W KDG+++V +
Sbjct: 1803 ------------QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSR 1850
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCC 3271
+ + + I D G Y N+ G+ SC L V+D+ I P F
Sbjct: 1851 YFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNI----PPSFTK 1906
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L + K+ G + + V + W++DG + S + + + + L + +
Sbjct: 1907 KLTKMDKV-LGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC-HERSVSLEVNNL 1964
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEV 3358
D YTC SN G + SG + V
Sbjct: 1965 ELEDTANYTCKVSNVAGDDACSGILTV 1991
Score = 84.2 bits (199), Expect = 7e-15
Identities = 92/388 (23%), Positives = 149/388 (38%), Gaps = 52/388 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
S+S + P P ++ L +L C + G P VVW K+ ++
Sbjct: 2169 STSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKY 2228
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ N F + I +++ D G Y C+A N G +D V KLK
Sbjct: 2229 KIASKN-FHTSIHILNVDTSDIGEYHCKAQNEVG-----------SDTCV--CTVKLKE- 2273
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
PP+F +L V A P L + G+ P V W K+ EEV+ + +
Sbjct: 2274 ---------PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRI 2324
Query: 3218 Q-DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
E TL+ A + G Y +N+ G L+V + P
Sbjct: 2325 TFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV-------LEPAVIVEKAGP 2377
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+ + V P + V WY+DG L S++ + + L + +V +DA
Sbjct: 2378 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 2436
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G YT N VG++S + V+V S+ +P P F R+ +++
Sbjct: 2437 GTYTFQVQNNVGKSSCTAVVDV------SDRAVP-------------PSFTRRLKNTGGV 2477
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
G + I+EC+V G V W + K+
Sbjct: 2478 LGASCILECKVAGSSPISVAWFHEKTKI 2505
Score = 83.8 bits (198), Expect = 1e-14
Identities = 75/310 (24%), Positives = 133/310 (42%), Gaps = 38/310 (12%)
Query: 3042 GVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTS 3100
G+ + P F+ + PG+ + + T +KG P + W K+ +VE +G +
Sbjct: 1987 GILTVKEPPSFL-VKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKD--DVELVSGPKCFI 2043
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA 3160
G L + ++ G+Y+C TN G S L +VT+
Sbjct: 2044 GLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTML-LVTE---------------- 2086
Query: 3161 EVEGDYPPQFTMRLRDRR-VQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQ 3218
PP+F +L + V+A RL C++ GSP +V W+++ E+ DK R +
Sbjct: 2087 ------PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFI 2140
Query: 3219 DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
D +++ + +D G + A+N +G+ SC ++V + P P+ +
Sbjct: 2141 D-SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE-------PPVFSSFPPIVE 2192
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ E+ + + P V WY+D +LR S++ ++ + + V T D G
Sbjct: 2193 TLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKK-YKIASKNFHTSIHILNVDTSDIGE 2251
Query: 3339 YTCTASNEVG 3348
Y C A NEVG
Sbjct: 2252 YHCKAQNEVG 2261
Score = 83.4 bits (197), Expect = 1e-14
Identities = 82/359 (22%), Positives = 140/359 (38%), Gaps = 53/359 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEGR 3121
L G TA ++KG V W+K+ E+ E+ RMT + N L + I + +G+
Sbjct: 1163 LRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNV--ASLYLSGIEVKHDGK 1220
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C+A N G A L+V T+ E + +GD
Sbjct: 1221 YVCQAKNDAGIQRCSALLSVKEPATITEEAVSID-----VTQGD---------------- 1259
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P L + G+ W+KDG+E+ + + L+I T D G Y
Sbjct: 1260 --PATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE 1317
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G SC + V + + P F L+ + + +G + + +V + + W
Sbjct: 1318 VQNDVGRSSCKARINV---LDLIIPPSFTKKLKKMDSI-KGSFIDLECIVAGSHPISIQW 1373
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++D + S + + D L ++ + D+G YTC+A+N+ G SG + V
Sbjct: 1374 FKDDQEISASEKYKFSF-HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV--- 1429
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
EP P F+ KP+S + V ++ V G + W +D
Sbjct: 1430 ---KEP----------------PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKD 1469
Score = 83.4 bits (197), Expect = 1e-14
Identities = 84/352 (23%), Positives = 142/352 (40%), Gaps = 52/352 (14%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V G P V W+K+G ++ + F I+ + D G+Y+ + N
Sbjct: 1825 LECVVAGTPELKVKWLKDGKQIVPSR-YFSMSFENNVASFRIQSVMKQDSGQYTFKVEND 1883
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G +S A L V+ D+ + PP FT +L + + C
Sbjct: 1884 FGSSSCDAYLRVL-DQNI-------------------PPSFTKKLTKMDKVLGSSIHMEC 1923
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+V GS P W+KDG+E+ + E+ +LE+ L+D Y N +G
Sbjct: 1924 KVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDD 1983
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
+C L V + V P G + + + A+++ P + W++D V L
Sbjct: 1984 ACSGILTVKEPPSFLVKP----GRQ---QAIPDSTVEFKAILKGTPPFKIKWFKDDVELV 2036
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
+ + L+ L L +V G YTC +N+VG S + + V +EP
Sbjct: 2037 SGPKCFIGLEGSTSF-LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLV------TEP-- 2087
Query: 3370 PPVVISPDVPYSKEPMFIRKPRSSE-AREGDTVIIECEVVGDPKPDVYWLRD 3420
P F++K +S+ + GD+ +EC++ G P+ V W R+
Sbjct: 2088 --------------PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRN 2125
Score = 83.4 bits (197), Expect = 1e-14
Identities = 83/353 (23%), Positives = 137/353 (38%), Gaps = 43/353 (12%)
Query: 2591 TRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
T P F+ L + + GS V + C V S +V+W+ G + + KY+ L D
Sbjct: 4344 TVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L V SDS +Y+C N G+ SA L V PP+F + L
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE-------PPSFVQKPDPMDVLTGTN 4456
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+ ++G P ++WFK ++ R L D V L + + SG YTC
Sbjct: 4457 VTFTSIVKGTPPFSVSWFKGSSELVPGDRCNV-SLEDSVAELELFDVDTSQSGEYTCIVS 4515
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N G+ S + + A + R L DY + +G +
Sbjct: 4516 NE------------AGKASCTTHLYIKAPAKFVKR-------------LNDYSIEKGKPL 4550
Query: 2831 GLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ G P V W + G +VT R + + L + T ++G Y C +
Sbjct: 4551 ILEGTFTGTPPISVTWKKNGINVTPSQR-CNITTTEKSPILEIPSSTVEDAGQYNCYIEN 4609
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
A G +A I +++P P + + + + +SVG+ ++ + G P+
Sbjct: 4610 ASGKDSCSAQILILEP------PYFV--KQLEPVKVSVGDSASLQCQLAGTPE 4654
Score = 82.6 bits (195), Expect = 2e-14
Identities = 81/320 (25%), Positives = 134/320 (41%), Gaps = 32/320 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F + D A+ G V L +V S +VTW + ++ K + +G+ L +
Sbjct: 589 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLII 648
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ S +Y+C ENE G+ ++ L V E + I I+ T A + L
Sbjct: 649 PDVQISFGGKYTCLAENEAGSQTSVGELIVK---EPAKIIER-AELIQVT---AGDPATL 701
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E + G P K W+KD + + + +Y+ + + V +L + DSG YT + N V
Sbjct: 702 EYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDSGQYTFEISNEV 760
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
+ FT + ++ P F L + GT L
Sbjct: 761 GSSSCE--TTFTVLDRDIA--------------------PFFTKPLRNVDSVVNGTCRLD 798
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+I G P RV W ++G+ + R FVE G +L + V ++G +TCRA ++ G
Sbjct: 799 CKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-GTASLEIIRVDMNDAGNFTCRATNSVG 857
Query: 2893 NVDMNAAITVVQPSDLDGKP 2912
+ D + A+ V +P KP
Sbjct: 858 SKDSSGALIVQEPPSFVTKP 877
Score = 82.6 bits (195), Expect = 2e-14
Identities = 89/376 (23%), Positives = 150/376 (39%), Gaps = 54/376 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F L K+L G + ++ C V G W K+G E+ A + + L
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVSGSLPISAQWFKDGKEISTSA-KYRLVCHERSVSL 1959
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ ++ ++D Y+C+ +N G + L V +E PP
Sbjct: 1960 EVNNLELEDTANYTCKVSNVAGDDACSGILTV--------------KE---------PPS 1996
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F ++ ++ V + G+PP K+ W+KD E+V + + L +
Sbjct: 1997 FLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYS 2056
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ G Y N+ G+ SC L+V + P+F LE + GD R+
Sbjct: 2057 VDASKTGQYTCHVTNDVGSDSCTTMLLVTE------PPKFVKKLEASKIVKAGDSSRLEC 2110
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
+ P + V W+R+ L S + MT D + + ++T D+G + C A N G
Sbjct: 2111 KIAGSPEIRVVWFRNEHELPASDKYRMTFI-DSVAVIQMNNLSTEDSGDFICEAQNPAGS 2169
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
S S KV V + PPV +S P + +++E V +ECE+ G
Sbjct: 2170 TSCSTKVIV---------KEPPV-------FSSFPPIVETLKNAE------VSLECELSG 2207
Query: 3410 DPKPDVYWLRDFLKVR 3425
P +V W +D ++R
Sbjct: 2208 TPPFEVVWYKDKRQLR 2223
Score = 82.6 bits (195), Expect = 2e-14
Identities = 75/320 (23%), Positives = 127/320 (39%), Gaps = 35/320 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D + GS + L + + +V+W ++ L+ + + + LE+L +
Sbjct: 3598 LADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIE 3657
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D A+YSC +ENE G A + V PP F + + L+C++ G
Sbjct: 3658 DYAQYSCLIENEAGQDICEALVSVLE-------PPYFIEPLEHVEAVIGEPATLQCKVDG 3710
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P +I+W+K+ ++ S Y+ + V L I+ D G Y+CKA+NSV
Sbjct: 3711 TPEIRISWYKEHTKLRSAPAYK-MQFKNNVASLVINKVDHSDVGEYSCKADNSV------ 3763
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V+ + V K R P F L D G + + I G
Sbjct: 3764 ---------GAVASSAVLVIKAR-------KLPPFFARKLKDVHETLGFPVAFECRINGS 3807
Query: 2840 -PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P +V W ++G + + FV + TL + ++ G Y C A + G +A
Sbjct: 3808 EPLQVSWYKDGVLLKDDANLQTSFV-HNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 3866
Query: 2899 AITVVQ---PSDLDGKPAVI 2915
+ + + P D KP +
Sbjct: 3867 KLILSEHEVPPFFDLKPVSV 3886
Score = 82.2 bits (194), Expect = 3e-14
Identities = 90/365 (24%), Positives = 145/365 (39%), Gaps = 58/365 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G+ A L G W K+G E+ + S + L I D
Sbjct: 1253 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSI-LKIISTEKKDS 1311
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-R 3178
G Y+ E N G++S AR+ V+ D + PP FT +L+
Sbjct: 1312 GEYTFEVQNDVGRSSCKARINVL-DLII-------------------PPSFTKKLKKMDS 1351
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
++ ++ + L C V GS P + W+KD +E+ +K + + D LEI+ D G
Sbjct: 1352 IKGSF-IDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF-LEISQLEGTDSGT 1409
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
Y +A N +G C L V + P + ++ +++ A+V +
Sbjct: 1410 YTCSATNKAGHNQCSGHLTVKE-------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPM 1462
Query: 3298 GVTWYRDGVRLRP-SRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W++D L + R++ D +EL A T D+G Y C SN+VG A++ +
Sbjct: 1463 TIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKAT--DSGTYICQLSNDVGTATSKATL 1520
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS-SEAREGDTVIIECEVVGDPKPDV 3415
V EP P FI+KP R G + EC++ G PK V
Sbjct: 1521 FV------KEP----------------PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRV 1558
Query: 3416 YWLRD 3420
W D
Sbjct: 1559 SWYLD 1563
Score = 81.8 bits (193), Expect = 4e-14
Identities = 97/413 (23%), Positives = 156/413 (37%), Gaps = 59/413 (14%)
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
F + L +Y F ++ N G T + + +A P F L ++ G T
Sbjct: 741 FYSAELHDSGQYTFEIS--NEVGSSSCETTFTVLDRDIA---PFFTKPLRNVDSVVNG-T 794
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L C + G V W K+G E+ + R F L I ++++D G ++C AT
Sbjct: 795 CRLDCKIAGSLPMRVSWFKDGKEIAA-SDRYRIAFVEGTASLEIIRVDMNDAGNFTCRAT 853
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N+ G + L V PP F + + V V L
Sbjct: 854 NSVGSKDSSGALIV-----------------------QEPPSFVTKPGSKDVLPGSAVCL 890
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
GS P + W+K +E+V ++ +LE+ D G Y N +G
Sbjct: 891 KSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 950
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
V C L V + F LEP L +GD +++ V P + +TW+ +
Sbjct: 951 GVECSANLFVKE------PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDRE 1004
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
++ S + M+ + L L V D+G Y C A NE G+D S
Sbjct: 1005 IKESSKHRMSFVESTAV-LRLTDVGIEDSGEYMCEAQNEA------------GSDHCSS- 1050
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+VI + PY F ++ + E + V++ EV G P ++ W +D
Sbjct: 1051 ----IVIVKESPY-----FTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKD 1094
Score = 81.8 bits (193), Expect = 4e-14
Identities = 93/376 (24%), Positives = 142/376 (37%), Gaps = 55/376 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L IL G + L C V G V W ++G+E+ + S F+ C L
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVSGSAPISVGWFQDGNEIVS-GPKCQSSFSENVCTL 3463
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ + D G Y+C A N G A L TV E PP
Sbjct: 3464 NLSLLEPSDTGIYTCVAANVAGSDECSAVL------TVQE-----------------PPS 3500
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F V + T + G+PP KV W+K E+V + N ++ LE+
Sbjct: 3501 FEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFE 3560
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ G Y N++G+ SC L V + F L + + G + + A
Sbjct: 3561 VQPLESGDYSCLVTNDAGSASCTTHLFVKE------PATFVKRLAD-FSVETGSPIVLEA 3613
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
P + V+W +D + S R +T+ I L + T D Y+C NE G+
Sbjct: 3614 TYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI-LEILESTIEDYAQYSCLIENEAGQ 3672
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
V V+ EP PY EP+ EA G+ ++C+V G
Sbjct: 3673 DICEALVSVL------EP-----------PYFIEPL-----EHVEAVIGEPATLQCKVDG 3710
Query: 3410 DPKPDVYWLRDFLKVR 3425
P+ + W ++ K+R
Sbjct: 3711 TPEIRISWYKEHTKLR 3726
Score = 81.0 bits (191), Expect = 7e-14
Identities = 74/311 (23%), Positives = 118/311 (37%), Gaps = 35/311 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L V G+ L C V + ++W+++ + + KYR L+ LE+
Sbjct: 496 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 555
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ +D EY C V NE G A PPTF + + D L + L
Sbjct: 556 FSFNSADVGEYECVVANEVGKCGCMAT-------HLLKEPPTFVKKVDDLIALGGQTVTL 608
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ +RG +TW K + I DG+ + + ++GV L I + G YTC AEN
Sbjct: 609 QAAVRGSEPISVTWMKGQEVIREDGKIKMSF-SNGVAVLIIPDVQISFGGKYTCLAENE- 666
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
G ++ V +V I R L QV G L+
Sbjct: 667 -----------AGSQTSVGELIVKEPAKIIERAEL-------------IQVTAGDPATLE 702
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G P + +W ++GR + + R+ + + L +SG YT + G
Sbjct: 703 YTVAGTPELKPKWYKDGRPLV-ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 761
Query: 2893 NVDMNAAITVV 2903
+ TV+
Sbjct: 762 SSSCETTFTVL 772
Score = 79.4 bits (187), Expect = 2e-13
Identities = 76/323 (23%), Positives = 131/323 (40%), Gaps = 34/323 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ LT V GS + + C V S + W+++G + KYR + ++LEV
Sbjct: 1902 PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEV 1961
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
N D+A Y+C V N G + S L V PP+F + ++ +
Sbjct: 1962 NNLELEDTANYTCKVSNVAGDDACSGILTVKE-------PPSFLVKPGRQQAIPDSTVEF 2014
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ ++G P KI WFKDD ++ S G L L + + +G YTC N V
Sbjct: 2015 KAILKGTPPFKIKWFKDDVELVS-GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDV 2073
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
+D T + T + V E ++I + SR L+
Sbjct: 2074 GSDSCTTMLLVT----EPPKFVKKLEASKIVKAGDSSR--------------------LE 2109
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+I G P RV W R + + F++ + + +++++ +SG + C A + G
Sbjct: 2110 CKIAGSPEIRVVWFRNEHELPASDKYRMTFID-SVAVIQMNNLSTEDSGDFICEAQNPAG 2168
Query: 2893 NVDMNAAITVVQPSDLDGKPAVI 2915
+ + + V +P P ++
Sbjct: 2169 STSCSTKVIVKEPPVFSSFPPIV 2191
Score = 79.4 bits (187), Expect = 2e-13
Identities = 97/370 (26%), Positives = 138/370 (37%), Gaps = 51/370 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV L L ++AGE A L S++G V W+K EV E+ + F L
Sbjct: 2275 PRFVSKL-NSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATL 2333
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ G+Y C+ N G A L V+ E + VE P
Sbjct: 2334 QFAKAEPANAGKYICQIKNDGGMRENMATLMVL--------------EPAVIVEKAGPMT 2379
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
T V T L C+V G+P V WYKDG+ + ++ + +L I
Sbjct: 2380 VT-------VGET--CTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILS 2430
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
D G Y +NN G SC VVD RA V P F L+ + G +
Sbjct: 2431 VERQDAGTYTFQVQNNVGKSSCTA--VVDVSDRA-VPPSFTRRLKNTGGV-LGASCILEC 2486
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
V + V W+ + ++ S T D L L ++ + D G YTC A+N
Sbjct: 2487 KVAGSSPISVAWFHEKTKI-VSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAAN---- 2541
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
V G+D+ V++ P P F+++P E G V + G
Sbjct: 2542 --------VAGSDECR------AVLTVQEP----PSFVKEPEPLEVLPGKNVTFTSVIRG 2583
Query: 3410 DPKPDVYWLR 3419
P V W R
Sbjct: 2584 TPPFKVNWFR 2593
Score = 79.0 bits (186), Expect = 3e-13
Identities = 68/306 (22%), Positives = 127/306 (41%), Gaps = 32/306 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D + +G + L + + +VTW +NG+ + + + LE+ ++
Sbjct: 4539 LNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVE 4598
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ +Y+C +EN +G S SA + + PP F + + + L+C++ G
Sbjct: 4599 DAGQYNCYIENASGKDSCSAQILILE-------PPYFVKQLEPVKVSVGDSASLQCQLAG 4651
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P ++W+K D ++ Y+ + + V L + DSG Y CKAENSV +
Sbjct: 4652 TPEIGVSWYKGDTKLRPTTTYK-MHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAS 4710
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
F+ T +E ++ P+ F L D Q G + I G
Sbjct: 4711 TFL--TVQEQKLPPS--------------------FSRQLRDVQETVGLPVVFDCAISGS 4748
Query: 2840 -PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P V W ++G+ + + N + TL + + +G Y+C A + G+ +A
Sbjct: 4749 EPISVSWYKDGKPLKD-SPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSA 4807
Query: 2899 AITVVQ 2904
+ + +
Sbjct: 4808 RLILTE 4813
Score = 78.2 bits (184), Expect = 5e-13
Identities = 78/336 (23%), Positives = 128/336 (38%), Gaps = 35/336 (10%)
Query: 2571 KAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN 2630
KA +E SV S TL+ P F + T G K C+V + W ++
Sbjct: 194 KASNEYGSV-SCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKD 252
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
G L +R + LE+ N D YSC N+ GA A L +
Sbjct: 253 GAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK---- 308
Query: 2691 PIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC 2750
P F + + ++ LEC++ +TW KD +++P Y+ + D +
Sbjct: 309 ---PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIA 364
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLES 2810
L I +DSGTY C A N + S S V E ++
Sbjct: 365 TLEIPLAKLKDSGTYVCTASNEAGS-------------SSCSATVTVREPPSFVKK---- 407
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYT 2869
V Y + G + L +++G P +V W + + ++E R++
Sbjct: 408 -------VDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSE-SNTVRMYFVNSEAI 459
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
L ++DV +SG Y+C A + G+ + I + +P
Sbjct: 460 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 495
Score = 77.4 bits (182), Expect = 9e-13
Identities = 66/260 (25%), Positives = 104/260 (40%), Gaps = 20/260 (7%)
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
P E PP ++DT +CR+ G L K++W+ DK+I ++
Sbjct: 1 PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQ 59
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
D +L I PED GTYT A N+V V+ T S +P + E+
Sbjct: 60 FED-TYQLEIAEAYPEDEGTYTFVANNAVGQ------VSSTANLSLEAPESILHERIEQE 112
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFV 2863
+ P + +VA G EI+ P R +W + GR E+Y + + +
Sbjct: 113 IEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGR---EIYESDKCSI 169
Query: 2864 EQGLY--TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEK 2921
Y +L + + G YTC+A + +G+V A +TV + P + RP K
Sbjct: 170 RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT-----EAYPPTFLSRP-K 223
Query: 2922 DILISVGEDINISFRTQGEP 2941
+ VG+ G P
Sbjct: 224 SLTTFVGKAAKFICTVTGTP 243
Score = 77.4 bits (182), Expect = 9e-13
Identities = 89/370 (24%), Positives = 146/370 (39%), Gaps = 58/370 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+++ AG+ A L +V G P W K+G + S F L + D
Sbjct: 691 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRIS-FKNNVAQLKFYSAELHDS 749
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y+ E +N G +S V+ DR D P FT LR+
Sbjct: 750 GQYTFEISNEVGSSSCETTFTVL-DR-------------------DIAPFFTKPLRNVDS 789
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL C++ GS P +VSW+KDG+E+ R E +LEI +++D G +
Sbjct: 790 VVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFT 849
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEAYPSVG 3298
A N+ G+ L+V + P F +P K + G + + + + +
Sbjct: 850 CRATNSVGSKDSSGALIVQE------PPSFV--TKPGSKDVLPGSAVCLKSTFQGSTPLT 901
Query: 3299 VTWYRDGVRLRPSRRAIMTLDR-DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W++ L +T + + +EL L V T D+G YTC SN G S +
Sbjct: 902 IRWFKGNKELVSGGSCYITKEALESSLELYL--VKTSDSGTYTCKVSNVAGGVECSANL- 958
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEP-MFIRKPRSSE-AREGDTVIIECEVVGDPKPDV 3415
+ KEP F+ K S+ ++GD + C+V G P +
Sbjct: 959 ----------------------FVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKI 996
Query: 3416 YWLRDFLKVR 3425
W + +++
Sbjct: 997 TWFANDREIK 1006
Score = 76.2 bits (179), Expect = 2e-12
Identities = 74/309 (23%), Positives = 117/309 (37%), Gaps = 29/309 (9%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV L L G+ L V+G VVW+K+ EV E+ F L
Sbjct: 3216 PRFVKKL-SDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATL 3274
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ + G+Y C+ N G A L V+ + E K E G+
Sbjct: 3275 QLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIE-----KPEPMTVTTGN---- 3325
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
P L C V G+P W+KDG E+ D + + + +L+I
Sbjct: 3326 --------------PFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPC 3371
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ D G+Y +N+ G +C + V I V P F L+ + + G + +
Sbjct: 3372 AEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRI---VPPSFIRKLKDVNAI-LGASVVLEC 3427
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
V + V W++DG + + + + L L+ + D G+YTC A+N G
Sbjct: 3428 RVSGSAPISVGWFQDGNEIVSGPKCQSSFS-ENVCTLNLSLLEPSDTGIYTCVAANVAGS 3486
Query: 3350 ASTSGKVEV 3358
S + V
Sbjct: 3487 DECSAVLTV 3495
Score = 75.4 bits (177), Expect = 3e-12
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 5/170 (2%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E + L C V + + V W ++G + + + + + + + + DS +Y+
Sbjct: 1819 EKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTF 1878
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
VEN+ G+ S A L+V IPP+FT+ + + + + +EC++ G
Sbjct: 1879 KVENDFGSSSCDAYLRVLDQ----NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 1934
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
WFKD K+I + +Y+ V L ++N ED+ YTCK N D
Sbjct: 1935 WFKDGKEISTSAKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDD 1983
Score = 75.4 bits (177), Expect = 3e-12
Identities = 79/348 (22%), Positives = 142/348 (40%), Gaps = 41/348 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PVF+ + A++GS V L C + + V W ++ + N K++ L +
Sbjct: 3123 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHI 3182
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
LN SD EY C NE G+ + S ++K F+ PP F + + DT L + + L
Sbjct: 3183 LNLEASDVGEYHCKATNEVGSDTCSCSVK----FKE---PPRFVKKLSDTSTLIGDAVEL 3235
Query: 2714 ECRIRG-QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ G QP+ + W KD ++ + D + L + +P +SG Y C+ +N
Sbjct: 3236 RAIVEGFQPI-SVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKND 3294
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ S + E RI +E P V G L
Sbjct: 3295 AGM-------------RECSAVLTVLEPARI----IEKPEP--------MTVTTGNPFAL 3329
Query: 2833 QVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P +W ++GR ++ ++ F+ + + +L + ++ GLY+ ++
Sbjct: 3330 ECVVTGTPELSAKWFKDGRELSADSKHHITFINK-VASLKIPCAEMSDKGLYSFEVKNSV 3388
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQG 2939
G + ++ V SD P+ I R KD+ +G + + R G
Sbjct: 3389 GKSNCTVSVHV---SDRIVPPSFI--RKLKDVNAILGASVVLECRVSG 3431
Score = 74.9 bits (176), Expect = 5e-12
Identities = 81/360 (22%), Positives = 140/360 (38%), Gaps = 40/360 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L + V G+ L C V SS +V W+ + + KY+ D + TL++
Sbjct: 2465 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 2524
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ SD Y+C N G+ A L V PP+F + L +
Sbjct: 2525 NSLDSSDMGNYTCVAANVAGSDECRAVLTVQE-------PPSFVKEPEPLEVLPGKNVTF 2577
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
IRG P K+ WF+ +++ R Y D V L + N SG YTC N+
Sbjct: 2578 TSVIRGTPPFKVNWFRGARELVKGDRCN-IYFEDTVAELELFNIDISQSGEYTCVVSNN- 2635
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
G+ S + V + R S D+ V G +I L+
Sbjct: 2636 -----------AGQASCTTRLFVKEPAAFLKRLS-------------DHSVEPGKSIILE 2671
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G P V W ++G ++T + + L + + T+ ++G Y+C + G
Sbjct: 2672 STYTGTLPISVTWKKDGFNIT-TSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAG 2730
Query: 2893 NVDMNAAITVVQP----SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPE 2948
A ++ ++P ++L+ A + ++ +I +S+ +G+ K + PE
Sbjct: 2731 RDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSW-YKGDTKLRPTPE 2789
Score = 74.5 bits (175), Expect = 6e-12
Identities = 75/315 (23%), Positives = 128/315 (40%), Gaps = 37/315 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L + +V +L C + S V+W+++G + +YR V+G +LE+
Sbjct: 778 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEI 837
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ +D+ ++C N G+ +S L V PP+F L + + L
Sbjct: 838 IRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------PPSFVTKPGSKDVLPGSAVCL 890
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV-CRLAIDNPTPEDSGTYTCKAENS 2772
+ +G I WFK +K++ S G + + + L + DSGTYTCK N
Sbjct: 891 KSTFQGSTPLTIRWFKGNKELVSGG--SCYITKEALESSLELYLVKTSDSGTYTCKVSN- 947
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ S N+ E +E P + +G L
Sbjct: 948 ------------VAGGVECSANLFVKEPATF----VEKLEP-------SQLLKKGDATQL 984
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
++ G P ++ W R + E ++ FVE L L+DV +SG Y C A +
Sbjct: 985 ACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYMCEAQNEA 1043
Query: 2892 GNVDMNAAITVVQPS 2906
G+ D ++I +V+ S
Sbjct: 1044 GS-DHCSSIVIVKES 1057
Score = 73.7 bits (173), Expect = 1e-11
Identities = 88/363 (24%), Positives = 137/363 (37%), Gaps = 52/363 (14%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G L + G P V W+K+ + + + R + L I + I+D +YSC
Sbjct: 3606 GSPIVLEATYTGTPPISVSWIKDEYLISQSE-RCSITMTEKSTILEILESTIEDYAQYSC 3664
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
N G+ A ++V+ PP F L P
Sbjct: 3665 LIENEAGQDICEALVSVLE-----------------------PPYFIEPLEHVEAVIGEP 3701
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C+V G+P ++SWYK+ ++ +L I + D G Y A N
Sbjct: 3702 ATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADN 3761
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAYPSVGVTWY 3302
+ GAV+ LV I+A P F L +HE G + + + V+WY
Sbjct: 3762 SVGAVASSAVLV----IKARKLPPFFA--RKLKDVHETLGFPVAFECRINGSEPLQVSWY 3815
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+DGV L+ + T L + G Y C+ASN +G AS+S K+ +
Sbjct: 3816 KDGVLLKDDAN-LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL---- 3870
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
SE +P P F KP S + G++ +C V G + W +D
Sbjct: 3871 --SEHEVP-------------PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNR 3915
Query: 3423 KVR 3425
++R
Sbjct: 3916 EIR 3918
Score = 72.5 bits (170), Expect = 2e-11
Identities = 84/350 (24%), Positives = 137/350 (39%), Gaps = 43/350 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L D A+ G+ V L C V S+ +V W+++G + + K + + + TL +
Sbjct: 3406 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 3465
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
PSD+ Y+C N G+ SA L V PP+F ++ L L
Sbjct: 3466 SLLEPSDTGIYTCVAANVAGSDECSAVLTVQE-------PPSFEQTPDSVEVLPGMSLTF 3518
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
IRG P K+ WFK +++ G L D V L + P +SG Y+C N
Sbjct: 3519 TSVIRGTPPFKVKWFKGSREL-VPGESCNISLEDFVTELELFEVQPLESGDYSCLVTND- 3576
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
G S + V T + R L D+ V G I L+
Sbjct: 3577 -----------AGSASCTTHLFVKEPATFVKR-------------LADFSVETGSPIVLE 3612
Query: 2834 VEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G P V W+++ +++ R + E+ L + + T + Y+C + G
Sbjct: 3613 ATYTGTPPISVSWIKDEYLISQSERCSITMTEKST-ILEILESTIEDYAQYSCLIENEAG 3671
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
A ++V++P P I P + + +GE + + G P+
Sbjct: 3672 QDICEALVSVLEP------PYFI--EPLEHVEAVIGEPATLQCKVDGTPE 3713
Score = 72.1 bits (169), Expect = 3e-11
Identities = 81/315 (25%), Positives = 121/315 (38%), Gaps = 37/315 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P F+ L I+ G A L C V G + W K+ ++ R+ SQ + C
Sbjct: 496 PSFIKTLE-PADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV--C 552
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I N D G Y C N GK A L +E PP
Sbjct: 553 LEIFSFNSADVGEYECVVANEVGKCGCMA--------------THLLKE---------PP 589
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
F ++ D V L V GS P V+W K G+EV+ + + K + I
Sbjct: 590 TFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMK-GQEVIREDGKIKMSFSNGVAVLII 648
Query: 3229 P-TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
P + GG Y A N +G+ + L+V + + E L ++ GD +
Sbjct: 649 PDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAE-------LIQVTAGDPATL 701
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
V P + WY+DG L S++ ++ ++ +L + D+G YT SNEV
Sbjct: 702 EYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDSGQYTFEISNEV 760
Query: 3348 GRASTSGKVEVIGTD 3362
G +S V+ D
Sbjct: 761 GSSSCETTFTVLDRD 775
Score = 69.3 bits (162), Expect = 2e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 11/169 (6%)
Query: 2609 SRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTV 2668
+RV+L V ++ T+ W+++ L + D +LE+ A +DS Y C +
Sbjct: 1448 TRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQL 1507
Query: 2669 ENENGAISTSANL--KVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
N+ G ++ A L K P F P P R+ + T EC+I G P +++
Sbjct: 1508 SNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQST--------TFECQITGTPKIRVS 1559
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
W+ D +I + ++ ++ DG+ I E+SGTY C+A N T
Sbjct: 1560 WYLDGNEITAIQKHGISFI-DGLATFQISGARVENSGTYVCEARNDAGT 1607
Score = 68.1 bits (159), Expect = 5e-10
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 7/178 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F ++G+ V L C + + V+WY++ L + KY+ + L ++ +
Sbjct: 4064 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHI 4123
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
LN +D EY C N+ G+ + ++ A PP F + + D + E+ L
Sbjct: 4124 LNVDAADIGEYQCKATNDVGSDTCVGSI-------ALKAPPRFVKKLSDISTVVGKEVQL 4176
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ I G + WFKD +I + ++ + L P ++G YTC+ +N
Sbjct: 4177 QTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKN 4234
Score = 66.9 bits (156), Expect = 1e-09
Identities = 69/269 (25%), Positives = 108/269 (40%), Gaps = 38/269 (14%)
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
YPP L+D P R C+V G+ KVSWY +++ + Q E + L
Sbjct: 8 YPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQL 66
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-------VVDKGIRAYV------APEFCCG 3272
EIA +D G Y A N G VS L ++ + I + AP
Sbjct: 67 EIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRK 126
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAV 3331
+EPL ++ G + + +++ P+V W++ G + S + +I + +E+ V
Sbjct: 127 IEPL-EVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQV 185
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
D G YTC ASNE G S + + V T+ + P F+ +P+
Sbjct: 186 V--DCGEYTCKASNEYGSVSCTATLTV--TE------------------AYPPTFLSRPK 223
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
S G C V G P + W +D
Sbjct: 224 SLTTFVGKAAKFICTVTGTPVIETIWQKD 252
Score = 66.5 bits (155), Expect = 2e-09
Identities = 51/210 (24%), Positives = 83/210 (39%), Gaps = 10/210 (4%)
Query: 2571 KAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN 2630
K ++A S + + + + PVF LT T EG V+L+C V S + W +
Sbjct: 4988 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKA 5047
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
G + + G LE+ + +DS +Y C N G+ +T + + + +
Sbjct: 5048 GREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVA 5107
Query: 2691 PIPP-------TFTRSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDD-KQIPSDGRYQ 2741
P F S + + E ++ G P+P + W K +Q+ GR
Sbjct: 5108 PATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVF 5167
Query: 2742 AFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
D +L I + T DSG Y C A N
Sbjct: 5168 IHQKGD-EAKLEIRDTTKTDSGLYRCVAFN 5196
Score = 65.3 bits (152), Expect = 4e-09
Identities = 52/196 (26%), Positives = 82/196 (41%), Gaps = 10/196 (5%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE L+C V+G + W+K G E++ + R + F L ++D+ D G Y C
Sbjct: 5025 GEYVQLSCHVQGSEPIRIQWLKAGREIKP-SDRCSFSFASGTAVLELRDVAKADSGDYVC 5083
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+A+N G +T +++ T+ + A + A V+G F + RV
Sbjct: 5084 KASNVAGSDTTKSKV------TIKDKPAVAPATKKAAVDGRL--FFVSEPQSIRVVEKTT 5135
Query: 3185 VRLTCQVIGSPPPKVSWYK-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
+V G P P V W K ++ R +Q LEI T D G+Y A
Sbjct: 5136 ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAF 5195
Query: 3244 NNSGAVSCHCGLVVDK 3259
N G + + L VD+
Sbjct: 5196 NEHGEIESNVNLQVDE 5211
Score = 62.1 bits (144), Expect = 3e-08
Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 15/175 (8%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P + L D T EG +T S + W+RNG +L + +++ ++ + L
Sbjct: 5409 EPAWERHLQDVTLKEGQTCTMTVQ-FSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLT 5467
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + D +Y+C E+ + TSA L++ EA PI FT+ I++
Sbjct: 5468 IADVRAEDQGQYTCKYED----LETSAELRI----EAEPI--QFTKRIQNIVVSEHQSAT 5517
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYT 2766
EC + +TW+K ++ +Y + DG C + I N TP+D G Y+
Sbjct: 5518 FECEVSFDD-AIVTWYKGPTELTESQKYN--FRNDGRCHYMTIHNVTPDDEGVYS 5569
Score = 60.9 bits (141), Expect = 8e-08
Identities = 56/262 (21%), Positives = 101/262 (38%), Gaps = 27/262 (10%)
Query: 3159 SAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ 3218
SA V PP F ++ + GS P V+W KD +E+ D
Sbjct: 1142 SARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF 1201
Query: 3219 DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
+ +L ++ + G Y A+N++G C L V + A + E
Sbjct: 1202 ENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP--ATITEEAVS-----ID 1254
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ +GD + + W++DG L + +++ I L + + +D+G
Sbjct: 1255 VTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSI-LKIISTEKKDSGE 1313
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
YT N+VGR+S ++ V+ +I P P F +K + ++ +G
Sbjct: 1314 YTFEVQNDVGRSSCKARINVLD------------LIIP-------PSFTKKLKKMDSIKG 1354
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
+ +EC V G + W +D
Sbjct: 1355 SFIDLECIVAGSHPISIQWFKD 1376
Score = 60.1 bits (139), Expect = 1e-07
Identities = 76/346 (21%), Positives = 130/346 (37%), Gaps = 35/346 (10%)
Query: 2568 HRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW 2627
++ + +E S I R R P F + +++ G ++ S TVTW
Sbjct: 1128 YQCRVTNEVGSSICSARVTLREP---PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTW 1184
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
++ + R + + +L + +Y C +N+ G SA L V
Sbjct: 1185 LKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE-- 1242
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
P T T + L+ + G WFKD +++ +Y+ + D
Sbjct: 1243 -----PATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYK-ISVTD 1296
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQS 2807
V L I + +DSG YT + +N V GR S K RI
Sbjct: 1297 TVSILKIISTEKKDSGEYTFEVQNDV------------GRSSC---------KARINVLD 1335
Query: 2808 LESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQG 2866
L P F L +G I L+ + G P ++W ++ + ++ + F +
Sbjct: 1336 L-IIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNT 1394
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKP 2912
+ L +S + T+SG YTC A + G+ + +TV +P KP
Sbjct: 1395 AF-LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKP 1439
Score = 46.8 bits (106), Expect = 0.001
Identities = 52/181 (28%), Positives = 78/181 (43%), Gaps = 33/181 (18%)
Query: 3065 GETANLTCSVKGKPVPGVV--WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
G+T +T VP V W +NG ++ + GR ++ LTI D+ +D+G+Y
Sbjct: 5424 GQTCTMTVQFS---VPNVKSEWFRNGRILKPQ-GRHKTEVEHKVHKLTIADVRAEDQGQY 5479
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+C+ Y L E A+L+ E AE P QFT R+++ V
Sbjct: 5480 TCK----------YEDL---------ETSAELRIE--AE-----PIQFTKRIQNIVVSEH 5513
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
C+V V+WYK E+ ++ N D + H + I DD GVY V A
Sbjct: 5514 QSATFECEV-SFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 5572
Query: 3243 R 3243
R
Sbjct: 5573 R 5573
Score = 43.2 bits (97), Expect = 0.017
Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 18/184 (9%)
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P K+SWYK E++ + D HTL + L D G Y +
Sbjct: 5346 INYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLV---------- 5395
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
CG + + P + L+ + L EG ++ V + P+V W+R+G L+P
Sbjct: 5396 -CGPHIASAKLTVIEPAWERHLQDV-TLKEGQTCTMT-VQFSVPNVKSEWFRNGRILKPQ 5452
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R ++ +L +A V D G YTC + TS ++ + RI
Sbjct: 5453 GRHKTEVEHKVH-KLTIADVRAEDQGQYTCKYED----LETSAELRIEAEPIQFTKRIQN 5507
Query: 3372 VVIS 3375
+V+S
Sbjct: 5508 IVVS 5511
Score = 38.7 bits (86), Expect = 0.36
Identities = 53/203 (26%), Positives = 79/203 (38%), Gaps = 21/203 (10%)
Query: 2571 KAFSEARSVISEKRTLSRNSTR-KPVFS-TFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
K F E S I ++ + + T K + + T L D AV +K+ I S WY
Sbjct: 5302 KEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLS-----WY 5356
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
+ L+ K+ + TL V N D Y G SA L V
Sbjct: 5357 KGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTV----- 5407
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
I P + R ++D L E + P K WF++ + + GR++ +
Sbjct: 5408 ---IEPAWERHLQDVT-LKEGQTCTMTVQFSVPNVKSEWFRNGRILKPQGRHKT-EVEHK 5462
Query: 2749 VCRLAIDNPTPEDSGTYTCKAEN 2771
V +L I + ED G YTCK E+
Sbjct: 5463 VHKLTIADVRAEDQGQYTCKYED 5485
Score = 38.7 bits (86), Expect = 0.36
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVF 2862
IA L P + L D + G T + V+ + EW R GR + R+ +
Sbjct: 5400 IASAKLTVIEPAWERHLQDVTLKEGQTCTMTVQFSVPNVKSEWFRNGRILKPQGRH-KTE 5458
Query: 2863 VEQGLYTLALSDVTETESGLYTCR 2886
VE ++ L ++DV + G YTC+
Sbjct: 5459 VEHKVHKLTIADVRAEDQGQYTCK 5482
Score = 38.7 bits (86), Expect = 0.36
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 13/142 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT-L 2651
K + LT+ V GS C ++S S TW ++G + K+R + DG L
Sbjct: 7806 KEIKDIILTESEFV-GSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRF-IADGKDRKL 7862
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE- 2710
+++ SD+ EY+C + N +++A L V +P F +++ + + + +
Sbjct: 7863 HIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV------EELPVRFVKTLEEEVTVVKGQP 7916
Query: 2711 LVLECRIRGQPLPKITWFKDDK 2732
L L C + + + W KD K
Sbjct: 7917 LYLSCELNKE--RDVVWRKDGK 7936
Score = 37.9 bits (84), Expect = 0.64
Identities = 39/193 (20%), Positives = 78/193 (40%), Gaps = 3/193 (1%)
Query: 1268 VRNMSVSKEDEFFTEAIEMETITEQKQTDQTNELVKENIQETSQTDSKDLDVTIEKFGNE 1327
V +V +E F E + ++ + + +E + + + + V E+ E
Sbjct: 6122 VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREE-ERE 6180
Query: 1328 EEQKAKPTDEEIQNEDGHYLVKENKKQNKADTEIGKVEKQNKQEVDFV-KDQIEMELNEK 1386
EE++A+ T+ E+ E Y+V+E E E +QE V K +I ++ E
Sbjct: 6181 EEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEP 6240
Query: 1387 NASAIEEKTETTILPVKLEQEQVDERELANKEEENRKLEVSTARKKAEADSKKIQEEQGN 1446
+ + E + I+P K V ++E + + + KK K++E
Sbjct: 6241 PPAKVPEAPK-KIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPA 6299
Query: 1447 KSNEENSYTAKEK 1459
K E++ +E+
Sbjct: 6300 KVTEKHMQITQEE 6312
Score = 36.3 bits (80), Expect = 1.9
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 14/181 (7%)
Query: 1282 EAIEMETITEQKQTDQTNELVKENIQETSQTDSKDLDVTIEKFGNE-EEQKAKPTDEEIQ 1340
E +++ TIT +K+ + KE + E Q K+ V IE F +E + +P E +
Sbjct: 5700 EEVKIMTITRKKEVQKE----KEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFE 5755
Query: 1341 NEDGHYLVKENKKQNKADTEIGKVEKQNKQEVDFVKDQIEMELNEKNASAIEEKTETTIL 1400
Y + ++ + E K E + E DF + Q E E EE E
Sbjct: 5756 QP---YYEEPDEDYEEIKVE-AKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAY-- 5809
Query: 1401 PVKLEQEQVDERELANKEEENRKLEVSTARKKAEADSKKIQEEQGNKSNEENSYTAKEKT 1460
E+E + ++ +E RK+ KKA K I++ K + + +EK
Sbjct: 5810 ---QEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKV 5866
Query: 1461 K 1461
+
Sbjct: 5867 Q 5867
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 121 bits (292), Expect = 4e-26
Identities = 103/387 (26%), Positives = 165/387 (42%), Gaps = 36/387 (9%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
S +SS+ + G P F DI + + GE+A+ C V G V W K+ E+
Sbjct: 9064 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRS- 9122
Query: 3095 AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL 3154
G+ + LT+ ++ D G+Y+C A N GK S A+L +
Sbjct: 9123 GGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI------------- 9169
Query: 3155 KRERSAEVEGDYPPQFTMRLRDRRVQATY--PVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
+ER PP FT RL + V+ T +L +V GS P V+WYK+ E+
Sbjct: 9170 -KERLI------PPSFTKRLSET-VEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTS 9221
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG 3272
L++ ++D G+Y N++G+ C +V+ + + P F
Sbjct: 9222 NCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKP---PVFDQH 9278
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L P+ + EG+ +++S V+ + + W + G ++PS R + G L L V
Sbjct: 9279 LTPV-TVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF-ASGTAVLELRDVA 9336
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D+G Y C ASN G +T KV + +P + P V F+ +P+S
Sbjct: 9337 KADSGDYVCKASNVAGSDTTKSKVTI-----KDKPAVAPATKKAAV--DGRLFFVSEPQS 9389
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWLR 3419
E T +V GDP P+V W +
Sbjct: 9390 IRVVEKTTATFIAKVGGDPIPNVKWTK 9416
Score = 121 bits (291), Expect = 5e-26
Identities = 90/295 (30%), Positives = 131/295 (44%), Gaps = 29/295 (9%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +K+ G+T L C+V G P W K+G E+ + S FN L I ++
Sbjct: 8519 PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG-LKIINVAP 8577
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G YS E N GK S A L V +DRTV PP FT +L++
Sbjct: 8578 SDSGVYSFEVQNPVGKDSCTASLQV-SDRTV-------------------PPSFTRKLKE 8617
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+ V + C+V GSPP VSW+ +G E+ ++ + L + D G
Sbjct: 8618 TNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSG 8677
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G+ C L V + P F +P+ L G + +++V+ P
Sbjct: 8678 DYTCIATNMAGSDECSAPLTVRE------PPSFVQKPDPMDVL-TGTNVTFTSIVKGTPP 8730
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
V+W++ L P R ++L+ D EL L V T +G YTC SNE G+AS
Sbjct: 8731 FSVSWFKGSSELVPGDRCNVSLE-DSVAELELFDVDTSQSGEYTCIVSNEAGKAS 8784
Score = 113 bits (273), Expect = 8e-24
Identities = 101/373 (27%), Positives = 162/373 (43%), Gaps = 52/373 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV L L+ G++ +L C V G P V W K ++ T F L
Sbjct: 7006 PYFVTELE-PLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRT-YFTNNVATL 7063
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+NI+D G Y+C+A N+ G AS+ +TV+ E PP
Sbjct: 7064 VFNKVNINDSGEYTCKAENSIGTASS---------KTVFRIQ-----------ERQLPPS 7103
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F +L+D PV LTC++ GS P +V WY+DG + D+ + TL+I
Sbjct: 7104 FARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQ 7163
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T+L G Y +A N G S L + + +P F ++P+ + G+
Sbjct: 7164 TDLSHSGQYSCSASNPLGTASSSARLTAREPKK---SPFF--DIKPVSIDVIAGESADFE 7218
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
V + +TW +D +RP +T + L + V D+G YTC A+N+VG
Sbjct: 7219 CHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP-HLRILKVGKGDSGQYTCQATNDVG 7277
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE-AREGDTVIIECEV 3407
+ S ++ V EP P F++K +S+ A++G+++ +EC++
Sbjct: 7278 KDMCSAQLSV------KEP----------------PKFVKKLEASKVAKQGESIQLECKI 7315
Query: 3408 VGDPKPDVYWLRD 3420
G P+ V W R+
Sbjct: 7316 SGSPEIKVSWFRN 7328
Score = 113 bits (273), Expect = 8e-24
Identities = 100/371 (26%), Positives = 144/371 (38%), Gaps = 52/371 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV P + +L G T VKG P V W K E+ R L
Sbjct: 8702 PSFVQ-KPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVP-GDRCNVSLEDSVAEL 8759
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ D++ G Y+C +N GKAS L + P +
Sbjct: 8760 ELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKA-----------------------PAK 8796
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F RL D ++ P+ L G+PP V+W K+G V +R N E+ LEI
Sbjct: 8797 FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPS 8856
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ ++D G Y N SG SC +++ P F LEP+ K+ GD +
Sbjct: 8857 STVEDAGQYNCYIENASGKDSCSAQILI------LEPPYFVKQLEPV-KVSVGDSASLQC 8909
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
+ P +GV+WY+ +LRP+ M R+ L V D+G Y C A N VG
Sbjct: 8910 QLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLVFNQVDINDSGEYICKAENSVGE 8968
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
S S + V E ++P P F R+ R + G V+ +C + G
Sbjct: 8969 VSASTFLTV------QEQKLP-------------PSFSRQLRDVQETVGLPVVFDCAISG 9009
Query: 3410 DPKPDVYWLRD 3420
V W +D
Sbjct: 9010 SEPISVSWYKD 9020
Score = 113 bits (271), Expect = 1e-23
Identities = 84/300 (28%), Positives = 139/300 (46%), Gaps = 32/300 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L C+V + + + W+++G L + KY+ + + L+++N PSDS YS
Sbjct: 8527 GDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFE 8586
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
V+N G S +A+L+V +PP+FTR +++T L+ + +V+EC++ G P ++W
Sbjct: 8587 VQNPVGKDSCTASLQV----SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSW 8642
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
F + +I S +YQ L D C L ++ DSG YTC A N +D+ + T R
Sbjct: 8643 FHEGNEISSGRKYQT-TLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECS--APLTVR 8699
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWL 2846
E P+ V ++P +VLT G + ++G P V W
Sbjct: 8700 E---PPSFV--------------QKPDPMDVLT------GTNVTFTSIVKGTPPFSVSWF 8736
Query: 2847 REGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPS 2906
+ G S V +E + L L DV ++SG YTC + G + + P+
Sbjct: 8737 K-GSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA 8795
Score = 112 bits (269), Expect = 2e-23
Identities = 100/363 (27%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L++ G A TC ++ P W K G E+ E + + + + + + L I + D
Sbjct: 4392 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE-SDKCSIRSSKYISSLEILRTQVVDC 4450
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C+A+N +G S A L TV EA YPP F R +
Sbjct: 4451 GEYTCKASNEYGSVSCTATL------TVTEA---------------YPPTFLSRPKSLTT 4489
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ C V G+P + W KDG + E H LE++ + D GVY
Sbjct: 4490 FVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYS 4549
Query: 3240 VTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N GA C L ++DK P F LEP+ ++ + V+ V
Sbjct: 4550 CKASNKFGADICQAELIIIDK-------PHFIKELEPVQSA-INKKVHLECQVDEDRKVT 4601
Query: 3299 VTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG +L P + I D+ +E+ LA + +D+G Y CTASNE G +S S V
Sbjct: 4602 VTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKL--KDSGTYVCTASNEAGSSSCSATVT 4659
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V R PP + +P ++ P G++ + C++ G P V W
Sbjct: 4660 V---------REPPSFVK-----KVDPSYLMLP-------GESARLHCKLKGSPVIQVTW 4698
Query: 3418 LRD 3420
++
Sbjct: 4699 FKN 4701
Score = 110 bits (265), Expect = 7e-23
Identities = 89/326 (27%), Positives = 135/326 (41%), Gaps = 33/326 (10%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
E+ +S S V + + P FV + +L GE+A L C +KG PV V W KN E+
Sbjct: 4648 EAGSSSCSATVTVR-EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELS 4706
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
E + + F + L I D+ ++D G YSCEA N G S
Sbjct: 4707 E-SNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSC----------------- 4748
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
S E+ PP F L + L C+V G+ P ++SW+KD +++ K
Sbjct: 4749 ------STEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSK 4802
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG 3272
+ + + LEI N D G YE N G C ++ + P F
Sbjct: 4803 KYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE------PPTFVKK 4856
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
++ L L G + + A V + VTW + +R + M+ +G L + V
Sbjct: 4857 VDDLIAL-GGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLIIPDVQ 4914
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEV 3358
G YTC A NE G ++ G++ V
Sbjct: 4915 ISFGGKYTCLAENEAGSQTSVGELIV 4940
Score = 109 bits (263), Expect = 1e-22
Identities = 94/369 (25%), Positives = 148/369 (40%), Gaps = 53/369 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L G+ A C+V G PV +W K+G + S L + ++ I
Sbjct: 4484 PKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHI-LELSNLTI 4542
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G YSC+A+N G A L ++ D+ P F L
Sbjct: 4543 QDRGVYSCKASNKFGADICQAELIII-DK----------------------PHFIKELEP 4579
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+ V L CQV V+W KDG+++ K +++ TLEI L D G
Sbjct: 4580 VQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSG 4639
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y TA N +G+ SC + V + P F ++P Y + G+ R+ ++ P
Sbjct: 4640 TYVCTASNEAGSSSCSATVTVRE------PPSFVKKVDPSYLMLPGESARLHCKLKGSPV 4693
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ VTW+++ L S M I L + V D+G Y+C A N+VG S S ++
Sbjct: 4694 IQVTWFKNNKELSESNTVRMYFVNSEAI-LDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 4752
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
+ EP P FI+ ++ G +++CEV G ++
Sbjct: 4753 VI------KEP----------------PSFIKTLEPADIVRGTNALLQCEVSGTGPFEIS 4790
Query: 3417 WLRDFLKVR 3425
W +D ++R
Sbjct: 4791 WFKDKKQIR 4799
Score = 109 bits (263), Expect = 1e-22
Identities = 105/378 (27%), Positives = 155/378 (41%), Gaps = 52/378 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F++ L ++ + GE A L C V G P + W K H A QF L
Sbjct: 7947 PYFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISWYKE-HTKLRSAPAYKMQFKNNVASL 8004
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I ++ D G YSC+A N+ G ++ A L + +ER PP
Sbjct: 8005 VINKVDHSDVGEYSCKADNSVGAVASSAVLVI--------------KERKL------PPF 8044
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F +L+D +PV C++ GS P +VSWYKDG + D TL+I
Sbjct: 8045 FARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQ 8104
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T+ G Y +A N G S L++ + + P F L+P+ L G+
Sbjct: 8105 TDQSHIGQYNCSASNPLGTASSSAKLILSE----HEVPPF-FDLKPVSVDLALGESGTFK 8159
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
V + +TW +D +RP MTL + L + V DAG YTC ASN G
Sbjct: 8160 CHVTGTAPIKITWAKDNREIRPGGNYKMTL-VENTATLTVLKVGKGDAGQYTCYASNIAG 8218
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE-AREGDTVIIECEV 3407
+ S S + V EP P FI+K S ++ + EC++
Sbjct: 8219 KDSCSAHLGV------QEP----------------PRFIKKLEPSRIVKQDEFTRYECKI 8256
Query: 3408 VGDPKPDVYWLRDFLKVR 3425
G P+ V W +D +++
Sbjct: 8257 GGSPEIKVLWYKDETEIQ 8274
Score = 109 bits (262), Expect = 2e-22
Identities = 98/353 (27%), Positives = 153/353 (43%), Gaps = 43/353 (12%)
Query: 2581 SEKRTLSRNSTRK--PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL 2638
+ +T+ R R+ P F+ L D G V LTC + S+ V WYR+GVLL +
Sbjct: 7087 ASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDE 7146
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANL-----KVYPSFEASPIP 2693
+ VD + TL++L S S +YSC+ N G S+SA L K P F+ P+
Sbjct: 7147 NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPV- 7205
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
SI D +A EC + G +ITW KD+K+I G Y L
Sbjct: 7206 -----SI-DV--IAGESADFECHVTGAQPMRITWSKDNKEIRPGGNY-TITCVGNTPHLR 7256
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I DSG YTC+A N V D + ++ + V E +++A+Q
Sbjct: 7257 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSV----KEPPKFVKKLEASKVAKQ------- 7305
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
G +I L+ +I G P +V W R + E ++ F+ + L +
Sbjct: 7306 -------------GESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFI-NSVALLTI 7351
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILI 2925
++ + +SG Y C A + G+ + A+TV P KP+ + D+++
Sbjct: 7352 NEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVIL 7404
Score = 107 bits (258), Expect = 5e-22
Identities = 93/363 (25%), Positives = 143/363 (39%), Gaps = 54/363 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L+G + + C V G P V W G+E+ T+ + C LT+ + D G Y
Sbjct: 8621 LSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDN-TCALTVNMLEESDSGDY 8679
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+C ATN G A L V RE PP F + V
Sbjct: 8680 TCIATNMAGSDECSAPLTV--------------RE---------PPSFVQKPDPMDVLTG 8716
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
V T V G+PP VSW+K E+V R N ++ LE+ + G Y
Sbjct: 8717 TNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIV 8776
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
N +G SC L + +F L Y + +G L + P + VTW
Sbjct: 8777 SNEAGKASCTTHLYIK------APAKFVKRLND-YSIEKGKPLILEGTFTGTPPISVTWK 8829
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
++G+ + PS+R +T I L + + T DAG Y C N G+ S S ++ ++
Sbjct: 8830 KNGINVTPSQRCNITTTEKSAI-LEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL--- 8885
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
EP P F+++ + GD+ ++C++ G P+ V W +
Sbjct: 8886 ---EP----------------PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDT 8926
Query: 3423 KVR 3425
K+R
Sbjct: 8927 KLR 8929
Score = 104 bits (250), Expect = 5e-21
Identities = 84/321 (26%), Positives = 130/321 (40%), Gaps = 37/321 (11%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+ A +G ++L C + S + V+W+RN L KY ++ + L + A DS
Sbjct: 7301 KVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSG 7360
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y C N G S S L V PP FT+ L ++++L+C I G P
Sbjct: 7361 DYICEAHNGVGDASCSTALTV-------KAPPVFTQKPSPVGALKGSDVILQCEISGTPP 7413
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
++ W KD KQ+ + +++ L I N D G Y CKA N V +D + V
Sbjct: 7414 FEVVWVKDRKQVRNSKKFK-ITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSV 7472
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PT 2841
F P F L+D G + L+ + G P
Sbjct: 7473 KF-------------------------KEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPI 7507
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
V WL++ V N R+ + TL L + SG Y C+ + G + +A +T
Sbjct: 7508 SVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLT 7567
Query: 2902 VVQPSDLDGKP---AVIVGRP 2919
V++P+ + KP V G P
Sbjct: 7568 VLEPARIIEKPEPMTVTTGNP 7588
Score = 104 bits (250), Expect = 5e-21
Identities = 105/399 (26%), Positives = 165/399 (41%), Gaps = 46/399 (11%)
Query: 3027 NRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK 3086
N Y S + S S + L + P FV L +K+ G++A+L C + G P GV W K
Sbjct: 8866 NCYIENASGKDSCSAQI-LILEPPYFVKQLE-PVKVSVGDSASLQCQLAGTPEIGVSWYK 8923
Query: 3087 NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRT 3146
++ F L ++I+D G Y C+A N+ G+ S L V
Sbjct: 8924 GDTKLRPTT-TYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV----- 8977
Query: 3147 VWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE 3206
+ KL PP F+ +LRD + PV C + GS P VSWYKDG+
Sbjct: 8978 ---QEQKL------------PPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK 9022
Query: 3207 EVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA 3266
+ + TL I T+ G Y TA N G+ S L++ +G
Sbjct: 9023 PLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN---P 9079
Query: 3267 PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIEL 3326
P F L P+ + G+ V + V+W +D +R + ++ + L
Sbjct: 9080 PFFDIRLAPVDAV-VGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISY-LENSAHL 9137
Query: 3327 ALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF 3386
+ V D+G YTC A NEVG+ S + ++ + E IPP ++K
Sbjct: 9138 TVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI------KERLIPP-------SFTK---- 9180
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
R + E EG++ +E V G V W ++ ++++
Sbjct: 9181 -RLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQ 9218
Score = 103 bits (248), Expect = 9e-21
Identities = 84/329 (25%), Positives = 140/329 (42%), Gaps = 42/329 (12%)
Query: 2615 CSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGA 2674
C + S + V WY++ + K+R VD + LE+ N DS +Y+C N G+
Sbjct: 8254 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGS 8313
Query: 2675 ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI 2734
S+S +LKV PP F + L ++ LEC ++G P ++W+KD +++
Sbjct: 8314 ASSSTSLKVKE-------PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKREL 8366
Query: 2735 PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPN 2794
S +Y+ + + + I N D G Y CKA N V +D
Sbjct: 8367 RSGKKYK-IMSENFLTSIHILNVDAADIGEYQCKATNDVGSD------------------ 8407
Query: 2795 VVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVT 2853
T + +L++ P F L+D G + LQ I G P V W ++ +
Sbjct: 8408 ------TCVGSIALKA-PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIV 8460
Query: 2854 EVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPA 2913
N + + + TL S V +G YTC+ + G + A ++V++ PA
Sbjct: 8461 RESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE-------PA 8513
Query: 2914 VIVGRPEKDILISVGEDINISFRTQGEPK 2942
IV +PE I ++ G+ + G P+
Sbjct: 8514 TIVEKPE-SIKVTTGDTCTLECTVAGTPE 8541
Score = 103 bits (248), Expect = 9e-21
Identities = 89/350 (25%), Positives = 144/350 (41%), Gaps = 34/350 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS L D G V C++ S +V+WY++G L + + +D TL +
Sbjct: 8984 PSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 9043
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
S + +YSCT N G+ S+SA L PP F + +
Sbjct: 9044 FKTDRSLAGQYSCTATNPIGSASSSARL----ILTEGKNPPFFDIRLAPVDAVVGESADF 9099
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
EC + G K++W KD ++I S G+YQ YL + L + DSG YTC A N V
Sbjct: 9100 ECHVTGTQPIKVSWAKDSREIRSGGKYQISYL-ENSAHLTVLKVDKGDSGQYTCYAVNEV 9158
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
D T +N +E + P+ T+ +++E G + L+
Sbjct: 9159 GKDSCTAQLNI--KERLIPPSF-----TKRLSETVEE--------------TEGNSFKLE 9197
Query: 2834 VEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G P V W + + + N + + L + ++GLYTC+ + G
Sbjct: 9198 GRVAGSQPITVAWYKNNIEI-QPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAG 9256
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQG-EP 2941
+ ++I + +P KP V + + +S GE + +S QG EP
Sbjct: 9257 SALCTSSIVIKEPK----KPPVF-DQHLTPVTVSEGEYVQLSCHVQGSEP 9301
Score = 103 bits (247), Expect = 1e-20
Identities = 76/304 (25%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L C V + + +V WY++G LL + K++ + + +L +L+ D+
Sbjct: 6641 TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGT 6700
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+ V+N G S +A + V +PP+FTR +++T + +LEC++ G
Sbjct: 6701 YTFQVQNNVGKSSCTAVVDV----SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPI 6756
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ WF + +I S +YQ + +D VC L +++ D G YTC A N +D+
Sbjct: 6757 SVAWFHEKTKIVSGAKYQTTF-SDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECR---- 6811
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
V+T ++ P F +V G + IRG P +
Sbjct: 6812 ----------AVLTVQEP-----------PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFK 6850
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V W R R + + R ++ E + L L ++ ++SG YTC + G + V
Sbjct: 6851 VNWFRGARELVKGDR-CNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 6909
Query: 2903 VQPS 2906
+P+
Sbjct: 6910 KEPA 6913
Score = 101 bits (243), Expect = 3e-20
Identities = 80/295 (27%), Positives = 126/295 (42%), Gaps = 36/295 (12%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KP F L + +V L C V TVTW ++G L Y+ D + TLE
Sbjct: 4570 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 4629
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ A DS Y CT NE G+ S SA + V PP+F + + ++ + E
Sbjct: 4630 IPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE-------PPSFVKKVDPSYLMLPGESA 4682
Query: 2713 -LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C+++G P+ ++TWFK++K++ S+ Y + L I + EDSG+Y+C+A N
Sbjct: 4683 RLHCKLKGSPVIQVTWFKNNKEL-SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVN 4741
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V +D S +V E P F L + RG
Sbjct: 4742 DVGSD-------------SCSTEIVIKEP------------PSFIKTLEPADIVRGTNAL 4776
Query: 2832 LQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTC 2885
LQ E+ G P + W ++ + + + R+F ++ L L + + G Y C
Sbjct: 4777 LQCEVSGTGPFEISWFKDKKQIRS-SKKYRLFSQKSLVCLEIFSFNSADVGEYEC 4830
Score = 101 bits (243), Expect = 3e-20
Identities = 96/370 (25%), Positives = 151/370 (40%), Gaps = 55/370 (14%)
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTI 3111
F DI P + ++AGE+A+ C V G + W K+ E+ G T G L I
Sbjct: 7199 FFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRP-GGNYTITCVGNTPHLRI 7257
Query: 3112 KDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFT 3171
+ D G+Y+C+ATN GK A+L+V +E PP+F
Sbjct: 7258 LKVGKGDSGQYTCQATNDVGKDMCSAQLSV--------------KE---------PPKFV 7294
Query: 3172 MRLRDRRV-QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPT 3230
+L +V + ++L C++ GSP KVSW+++ E+ + N L I
Sbjct: 7295 KKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEA 7354
Query: 3231 NLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAV 3290
+ +D G Y A N G SC L V P F P+ L +G ++ +
Sbjct: 7355 SAEDSGDYICEAHNGVGDASCSTALTVK------APPVFTQKPSPVGAL-KGSDVILQCE 7407
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
+ P V W +D ++R S++ +T + L + + D G Y C A+NEVG
Sbjct: 7408 ISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLHILNLEASDVGEYHCKATNEVGSD 7466
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ S V+ + + P F++K + GD V + V G
Sbjct: 7467 TCSCSVK----------------------FKEPPRFVKKLSDTSTLIGDAVELRAIVEGF 7504
Query: 3411 PKPDVYWLRD 3420
V WL+D
Sbjct: 7505 QPISVVWLKD 7514
Score = 101 bits (241), Expect = 6e-20
Identities = 100/376 (26%), Positives = 147/376 (39%), Gaps = 52/376 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV P L++L G+ T ++G P V W + E+ + R F L
Sbjct: 6820 PSFVKE-PEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVK-GDRCNIYFEDTVAEL 6877
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ +I+I G Y+C +N G+AS RL V +E P
Sbjct: 6878 ELFNIDISQSGEYTCVVSNNAGQASCTTRLFV--------------KE---------PAA 6914
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F RL D V+ + L G+ P V+W KDG + ++ N E+ LEI
Sbjct: 6915 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILN 6974
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ D G Y N +G CG +V P F LEPL + GD + +
Sbjct: 6975 STKRDAGQYSCEIENEAGRDV--CGALVS----TLEPPYFVTELEPL-EAAVGDSVSLQC 7027
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
V P + V+WY+ +LRP+ T + L V D+G YTC A N +G
Sbjct: 7028 QVAGTPEITVSWYKGDTKLRPTPE-YRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGT 7086
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
AS+ + E ++P P F R+ + E G V + C + G
Sbjct: 7087 ASSKTVFRI------QERQLP-------------PSFARQLKDIEQTVGLPVTLTCRLNG 7127
Query: 3410 DPKPDVYWLRDFLKVR 3425
V W RD + +R
Sbjct: 7128 SAPIQVCWYRDGVLLR 7143
Score = 99.1 bits (236), Expect = 2e-19
Identities = 98/384 (25%), Positives = 151/384 (39%), Gaps = 54/384 (14%)
Query: 3037 TSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG 3096
+ S G + + P FV PG +L G L + +G + W K E+ G
Sbjct: 5120 SKDSSGALIVQEPPSFVT-KPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVS-GG 5177
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
+ L + + D G Y+C+ +N G A L V +
Sbjct: 5178 SCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV--------------K 5223
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + VE P Q ++ AT +L C+V G+PP K++W+ + E+ +
Sbjct: 5224 EPATFVEKLEPSQLL-----KKGDAT---QLACKVTGTPPIKITWFANDREIKESSKHRM 5275
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
E L + ++D G Y A+N +G S HC +V Y EF +P+
Sbjct: 5276 SFVESTAVLRLTDVGIEDSGEYMCEAQNEAG--SDHCSSIVIVKESPYFTKEF----KPI 5329
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
L E D + + A V P +TW++D LR S R T +D + L + DA
Sbjct: 5330 EVLKEYD-VMLLAEVAGTPPFEITWFKDNTILR-SGRKYKTFIQDHLVSLQILKFVAADA 5387
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G Y C +NEVG + S +V + EP P FI+K S+ +
Sbjct: 5388 GEYQCRVTNEVGSSICSARVTL------REP----------------PSFIKKIESTSSL 5425
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
G T + + G V WL+D
Sbjct: 5426 RGGTAAFQATLKGSLPITVTWLKD 5449
Score = 99.1 bits (236), Expect = 2e-19
Identities = 96/372 (25%), Positives = 160/372 (43%), Gaps = 39/372 (10%)
Query: 2571 KAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN 2630
KA + +V S + + P F+ L D G V C + S V+WY++
Sbjct: 8020 KADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKD 8079
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
GVLL + + V + TL++L S +Y+C+ N G S+SA L + E
Sbjct: 8080 GVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL-ILSEHE-- 8136
Query: 2691 PIPPTF-TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV 2749
+PP F + + L E+ +C + G KITW KD+++I G Y+ L +
Sbjct: 8137 -VPPFFDLKPVSVDLALGESG-TFKCHVTGTAPIKITWAKDNREIRPGGNYK-MTLVENT 8193
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L + D+G YTC A N G++S S ++ E R ++ LE
Sbjct: 8194 ATLTVLKVGKGDAGQYTCYAS------------NIAGKDS-CSAHLGVQEPPRFIKK-LE 8239
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYT 2869
R + T Y+ GG+ EI +V W ++ + E + FV+ +
Sbjct: 8240 PSRIVKQDEFTRYECKIGGS----PEI-----KVLWYKDETEIQESSKFRMSFVD-SVAV 8289
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L + +++ +SG YTC A +A G+ + ++ V +P KP P + + G
Sbjct: 8290 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKP-----HPIETL---KGA 8341
Query: 2930 DINISFRTQGEP 2941
D+++ QG P
Sbjct: 8342 DVHLECELQGTP 8353
Score = 98.7 bits (235), Expect = 3e-19
Identities = 98/393 (24%), Positives = 159/393 (40%), Gaps = 56/393 (14%)
Query: 3029 YGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG 3088
Y + + S S +G+ + P F+ L + E C + G P V+W K+
Sbjct: 8212 YASNIAGKDSCSAHLGVQ-EPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDE 8270
Query: 3089 HEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVW 3148
E++E + + F L + +++++D G Y+CEA N G AS+ L V
Sbjct: 8271 TEIQESS-KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV------- 8322
Query: 3149 EADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
+ + R++ +E T++ D V L C++ G+PP VSWYKD E+
Sbjct: 8323 -KEPPIFRKKPHPIE-------TLKGAD--------VHLECELQGTPPFHVSWYKDKREL 8366
Query: 3209 VYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP 3267
K + K E F T + I + D G Y+ A N+ G+ +C G + K P
Sbjct: 8367 RSGK-KYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTC-VGSIALK-----APP 8419
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
F L + + G E+++ +E + V W++D + I + L
Sbjct: 8420 RFVKKLSDISTV-VGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 8478
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI 3387
+ V +AG YTC N+ +G E T EP +
Sbjct: 8479 FSRVEPANAGKYTCQIKND------AGMQECFATLSVLEP----------------ATIV 8516
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
KP S + GDT +EC V G P+ W +D
Sbjct: 8517 EKPESIKVTTGDTCTLECTVAGTPELSTKWFKD 8549
Score = 97.9 bits (233), Expect = 6e-19
Identities = 89/314 (28%), Positives = 130/314 (41%), Gaps = 30/314 (9%)
Query: 3045 LAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
L + P FV + L L G+T L +V+G V WMK G EV E G++ F+
Sbjct: 4846 LLKEPPTFVKKVD-DLIALGGQTVTLQAAVRGSEPISVTWMK-GQEVIREDGKIKMSFSN 4903
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG 3164
L I D+ I G+Y+C A N G ++ L V + AK+ ER+ ++
Sbjct: 4904 GVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIV-------KEPAKII-ERAELIQ- 4954
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
V A P L V G+P K WYKDG +V K+
Sbjct: 4955 --------------VTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQ 5000
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
L+ L D G Y N G+ SC V + +AP F L + + G
Sbjct: 5001 LKFYSAELHDSGQYTFEISNEVGSSSCETTFTV---LDRDIAPFFTKPLRNVDSVVNG-T 5056
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
R+ + + V+W++DG + S R + +G L + V DAG +TC A+
Sbjct: 5057 CRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAF-VEGTASLEIIRVDMNDAGNFTCRAT 5115
Query: 3345 NEVGRASTSGKVEV 3358
N VG +SG + V
Sbjct: 5116 NSVGSKDSSGALIV 5129
Score = 97.9 bits (233), Expect = 6e-19
Identities = 105/395 (26%), Positives = 156/395 (39%), Gaps = 58/395 (14%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV 3091
G+SS T+ + V P F L +L G + L C V G V W ++
Sbjct: 6710 GKSSCTAV-VDVSDRAVPPSFTRRLKNTGGVL-GASCILECKVAGSSPISVAWFHEKTKI 6767
Query: 3092 EEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEAD 3151
A T+ F+ C L + ++ D G Y+C A N G A L TV E
Sbjct: 6768 VSGAKYQTT-FSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL------TVQE-- 6818
Query: 3152 AKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD 3211
PP F V V T + G+PP KV+W++ E+V
Sbjct: 6819 ---------------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG 6863
Query: 3212 KRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC 3271
R N Y ++ LE+ ++ G Y NN+G SC L V K A++
Sbjct: 6864 DRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV-KEPAAFLKRLSDH 6922
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRA-IMTLDRDGQIELALAA 3330
+EP G + + + + VTW +DG + S + I+T ++ +E+ +
Sbjct: 6923 SVEP------GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNS- 6975
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
T RDAG Y+C NE GR V T EP P F+ +
Sbjct: 6976 -TKRDAGQYSCEIENEAGRDVCGALV------STLEP----------------PYFVTEL 7012
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
EA GD+V ++C+V G P+ V W + K+R
Sbjct: 7013 EPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 7047
Score = 97.9 bits (233), Expect = 6e-19
Identities = 90/346 (26%), Positives = 138/346 (39%), Gaps = 36/346 (10%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P+FV L GE+ L C + G P V W +N E+ E+ + F L
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSEL-HESWKYNMSFINSVALL 7349
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
TI + + +D G Y CEA N G AS L V PP
Sbjct: 7350 TINEASAEDSGDYICEAHNGVGDASCSTALTVKA-----------------------PPV 7386
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIA 3228
FT + V L C++ G+PP +V W KD ++ V + ++ K + F T L I
Sbjct: 7387 FTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQ-VRNSKKFKITSKHFDTSLHIL 7445
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
D G Y A N G+ +C C ++ P F L L GD + +
Sbjct: 7446 NLEASDVGEYHCKATNEVGSDTCSC------SVKFKEPPRFVKKLSDTSTL-IGDAVELR 7498
Query: 3289 AVVEAYPSVGVTWYRD-GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
A+VE + + V W +D G +R S ++ D L L + ++G Y C N+
Sbjct: 7499 AIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATLQLGSPEASNSGKYICQIKNDA 7557
Query: 3348 GRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
G S + V+ + E + P+ ++ P++ E + P S
Sbjct: 7558 GMRECSAVLTVLEPARIIE-KPEPMTVTTGNPFALECVVTGTPELS 7602
Score = 97.9 bits (233), Expect = 6e-19
Identities = 91/371 (24%), Positives = 155/371 (41%), Gaps = 46/371 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN-GVLLDNKLKYRKKLVDGLITLE 2652
P F L+D + V G V+L ++ + +V W+++ G ++ + + TL+
Sbjct: 8419 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 8478
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
P+++ +Y+C ++N+ G A L V P + + DT
Sbjct: 8479 FSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDT-------CT 8531
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
LEC + G P WFKD K++ SD +Y+ + + V L I N P DSG Y+ + +N
Sbjct: 8532 LECTVAGTPELSTKWFKDGKELTSDNKYKISFF-NKVSGLKIINVAPSDSGVYSFEVQNP 8590
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
V D T QVS V P F L + G ++ +
Sbjct: 8591 VGKDSCT-------ASLQVSDRTVP---------------PSFTRKLKETNGLSGSSVVM 8628
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ ++ G P V W EG ++ R + + L ++ + E++SG YTC A +
Sbjct: 8629 ECKVYGSPPISVSWFHEGNEISS-GRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 8687
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK-----PKAV 2946
G+ + +A +TV +P KP D+L G ++ + +G P K
Sbjct: 8688 GSDECSAPLTVREPPSFVQKP------DPMDVL--TGTNVTFTSIVKGTPPFSVSWFKGS 8739
Query: 2947 PERIPGEPCVV 2957
E +PG+ C V
Sbjct: 8740 SELVPGDRCNV 8750
Score = 97.5 bits (232), Expect = 7e-19
Identities = 88/353 (24%), Positives = 141/353 (39%), Gaps = 38/353 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F T L A G V L C V + + TV+WY+ L +YR + + TL V
Sbjct: 7006 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL-V 7064
Query: 2654 LNAVP-SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
N V +DS EY+C EN G S+ ++ + +PP+F R ++D +
Sbjct: 7065 FNKVNINDSGEYTCKAENSIGTASSKTVFRI----QERQLPPSFARQLKDIEQTVGLPVT 7120
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L CR+ G ++ W++D + D Q ++ D V L I SG Y+C A N
Sbjct: 7121 LTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFV-DNVATLKILQTDLSHSGQYSCSASNP 7179
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ T + T RE + S P F V G +
Sbjct: 7180 LGT--ASSSARLTAREPKKS--------------------PFFDIKPVSIDVIAGESADF 7217
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P R+ W ++ + + N + L + V + +SG YTC+A +
Sbjct: 7218 ECHVTGAQPMRITWSKDNKEI-RPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDV 7276
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
G +A ++V +P V + E + GE I + + G P+ K
Sbjct: 7277 GKDMCSAQLSVKEPPK-------FVKKLEASKVAKQGESIQLECKISGSPEIK 7322
Score = 97.5 bits (232), Expect = 7e-19
Identities = 82/327 (25%), Positives = 133/327 (40%), Gaps = 30/327 (9%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK 2637
S S R + P F L AV G C V + V+W ++ + +
Sbjct: 9064 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 9123
Query: 2638 LKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT 2697
KY+ ++ L VL DS +Y+C NE G S +A L + + IPP+FT
Sbjct: 9124 GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI----KERLIPPSFT 9179
Query: 2698 RSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
+ + +T E N LE R+ G + W+K++ +I + + + L +
Sbjct: 9180 KRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTLVLQVRK 9238
Query: 2757 PTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG 2816
D+G YTCK N + T ++V E + P F
Sbjct: 9239 AGMNDAGLYTCKVSNDAGSALCT-------------SSIVIKE---------PKKPPVFD 9276
Query: 2817 NVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDV 2875
LT V+ G + L ++G P R++WL+ GR + R + F G L L DV
Sbjct: 9277 QHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFA-SGTAVLELRDV 9335
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITV 2902
+ +SG Y C+A + G+ + +T+
Sbjct: 9336 AKADSGDYVCKASNVAGSDTTKSKVTI 9362
Score = 97.1 bits (231), Expect = 1e-18
Identities = 91/365 (24%), Positives = 144/365 (39%), Gaps = 53/365 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + + G L C V G P W K+G E+ ++ + N L I +
Sbjct: 7578 PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKV-ASLKIPCAEM 7636
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+G YS E N+ GK++ + V +DR V PP F +L+D
Sbjct: 7637 SDKGLYSFEVKNSVGKSNCTVSVHV-SDRIV-------------------PPSFIRKLKD 7676
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+V GS P V W++DG E+V + E TL ++ D G
Sbjct: 7677 VNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTG 7736
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
+Y A N +G+ C L V + P+ +E L G L ++V+ P
Sbjct: 7737 IYTCVAANVAGSDECSAVLTVQEPPSFEQTPD---SVEVL----PGMSLTFTSVIRGTPP 7789
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
V W++ L P ++L+ D EL L V ++G Y+C +N+ G AS + +
Sbjct: 7790 FKVKWFKGSRELVPGESCNISLE-DFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHL 7848
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEP-MFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
+ KEP F+++ G +++E G P V
Sbjct: 7849 -----------------------FVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISV 7885
Query: 3416 YWLRD 3420
W++D
Sbjct: 7886 SWIKD 7890
Score = 96.7 bits (230), Expect = 1e-18
Identities = 80/303 (26%), Positives = 128/303 (42%), Gaps = 35/303 (11%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+G +L C V + +TW+ N + K+R V+ L + + DS EY C
Sbjct: 5240 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMC 5299
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
+NE G+ S+ + V S P FT+ + L E +++L + G P +IT
Sbjct: 5300 EAQNEAGSDHCSSIVIVKES-------PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEIT 5352
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFKD+ + S +Y+ F + D + L I D+G Y C+ N V +
Sbjct: 5353 WFKDNTILRSGRKYKTF-IQDHLVSLQILKFVAADAGEYQCRVTNEVGS----------- 5400
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEW 2845
S S V E P F + RGGT Q ++G P V W
Sbjct: 5401 --SICSARVTLREP------------PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTW 5446
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
L++ +TE N R+ E + +L LS + G Y C+A + G +A ++V +P
Sbjct: 5447 LKDSDEITE-DDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP 5505
Query: 2906 SDL 2908
+ +
Sbjct: 5506 ATI 5508
Score = 96.7 bits (230), Expect = 1e-18
Identities = 92/354 (25%), Positives = 142/354 (40%), Gaps = 50/354 (14%)
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C + G V W K+G ++++A TS + L I + G+Y+C A+N G
Sbjct: 8064 CRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNV-ATLQILQTDQSHIGQYNCSASNPLG 8122
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
AS+ A+L + E + PP F ++ + C V
Sbjct: 8123 TASSSAKLILS--------------------EHEVPPFFDLKPVSVDLALGESGTFKCHV 8162
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G+ P K++W KD E+ E TL + D G Y A N +G SC
Sbjct: 8163 TGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSC 8222
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
L V + P F LEP + + + R + P + V WY+D ++ S
Sbjct: 8223 SAHLGVQE------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQES 8276
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
+ M+ D L + ++ D+G YTC A N G AS+S ++V EP
Sbjct: 8277 SKFRMSFV-DSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV------KEP---- 8325
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
P+F +KP E +G V +ECE+ G P V W +D ++R
Sbjct: 8326 ------------PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELR 8367
Score = 96.7 bits (230), Expect = 1e-18
Identities = 173/796 (21%), Positives = 295/796 (37%), Gaps = 85/796 (10%)
Query: 2608 GSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G+ V T S++ + P +V+W++ L + L D + LE+ + S S EY+C
Sbjct: 8716 GTNVTFT-SIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTC 8774
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
V NE G S + +L + P F + + D L+LE G P +T
Sbjct: 8775 IVSNEAGKASCTTHLYI-------KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 8827
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W K+ + R + L I + T ED+G Y C EN+ +G
Sbjct: 8828 WKKNGINVTPSQRCN-ITTTEKSAILEIPSSTVEDAGQYNCYIENA------------SG 8874
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEW 2845
++S + Q L P+F L +V+ G + LQ ++ G P V W
Sbjct: 8875 KDS-------------CSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW 8921
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ- 2904
+ G + ++ + TL + V +SG Y C+A ++ G V + +TV +
Sbjct: 8922 YK-GDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 8980
Query: 2905 --PSDLDGKPAVI---VGRPEK-DILISVGEDINISFRTQGEPKPKA--VPERIPGEPCV 2956
P + + VG P D IS E I++S+ G+P + V
Sbjct: 8981 KLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT 9040
Query: 2957 VDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEG-GARWVELGITPLNSFDAFNLKQ 3015
++ SLA S T P+ + + LI EG + ++ + P+++
Sbjct: 9041 LNIFKTDRSLAGQYSCTATN-PIGSASSSARLILTEGKNPPFFDIRLAPVDA--VVGESA 9097
Query: 3016 GEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC--- 3072
E H T + W + S+ S G + LK+ G++ TC
Sbjct: 9098 DFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLT--VLKVDKGDSGQYTCYAV 9155
Query: 3073 ------------SVKGKPVPGVVWMKNGHEVEEEAG---RMTSQFNGFD-CCLTIKDINI 3116
++K + +P + VEE G ++ + G + NI
Sbjct: 9156 NEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNI 9215
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVW------EADAKLKRERSAEVEGDYPPQF 3170
+ + +CE T + R A + D ++ +A + L E PP F
Sbjct: 9216 EIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 9275
Query: 3171 TMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPT 3230
L V V+L+C V GS P ++ W K G E+ R + LE+
Sbjct: 9276 DQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDV 9335
Query: 3231 NLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI--- 3287
D G Y A N +G+ + + + A + L+ + E +R+
Sbjct: 9336 AKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEK 9395
Query: 3288 -----SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
A V P V W + R + + + +L + T D+G+Y C
Sbjct: 9396 TTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCV 9455
Query: 3343 ASNEVGRASTSGKVEV 3358
A NE G ++ ++V
Sbjct: 9456 AFNEHGEIESNVNLQV 9471
Score = 96.3 bits (229), Expect = 2e-18
Identities = 90/376 (23%), Positives = 147/376 (39%), Gaps = 54/376 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F L ++ + G +L C V G + W K+ E+ + F+ L
Sbjct: 5602 PSFTKKLK-KMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASE-KYKFSFHDNTAFL 5659
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I + D G Y+C ATN G L V +E PP
Sbjct: 5660 EISQLEGTDSGTYTCSATNKAGHNQCSGHLTV--------------KE---------PPY 5696
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F + + + V V+L V G+ P + W+KD +E+ R+ ++D+ +LE+
Sbjct: 5697 FVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFA 5756
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
D G Y N+ G + L V + P+F P+ L G
Sbjct: 5757 AKATDSGTYICQLSNDVGTATSKATLFVKE------PPQFIKKPSPVLVLRNGQSTTFEC 5810
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
+ P + V+WY DG + ++ ++ DG ++ ++G Y C A N+ G
Sbjct: 5811 QITGTPKIRVSWYLDGNEITAIQKHGISF-IDGLATFQISGARVENSGTYVCEARNDAGT 5869
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
AS S +++V EP P FIR+ + E + V +ECEV G
Sbjct: 5870 ASCSIELKV------KEP----------------PTFIRELKPVEVVKYSDVELECEVTG 5907
Query: 3410 DPKPDVYWLRDFLKVR 3425
P +V WL++ ++R
Sbjct: 5908 TPPFEVTWLKNNREIR 5923
Score = 95.5 bits (227), Expect = 3e-18
Identities = 81/309 (26%), Positives = 127/309 (41%), Gaps = 35/309 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P F D+ P + + GE+ C V G + W K+ E+ +MT N
Sbjct: 8138 PPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN--TAT 8195
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
LT+ + D G+Y+C A+N GK S A L V PP
Sbjct: 8196 LTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGV-----------------------QEPP 8232
Query: 3169 QFTMRLRDRR-VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
+F +L R V+ R C++ GSP KV WYKD E+ + + LE+
Sbjct: 8233 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 8292
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+++D G Y A N +G+ S L V + P F P+ L +G ++ +
Sbjct: 8293 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE------PPIFRKKPHPIETL-KGADVHL 8345
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
++ P V+WY+D LR S + + + + + V D G Y C A+N+V
Sbjct: 8346 ECELQGTPPFHVSWYKDKRELR-SGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 8404
Query: 3348 GRASTSGKV 3356
G + G +
Sbjct: 8405 GSDTCVGSI 8413
Score = 95.5 bits (227), Expect = 3e-18
Identities = 82/314 (26%), Positives = 138/314 (43%), Gaps = 23/314 (7%)
Query: 2594 PVFSTFLTDRTA-VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F+ L++ EG+ KL V S TV WY+N + + + + L+
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQ 9235
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
V A +D+ Y+C V N+ G+ ++++ + + PP F + + ++E E V
Sbjct: 9236 VRKAGMNDAGLYTCKVSNDAGSALCTSSIVI----KEPKKPPVFDQHLTPV-TVSEGEYV 9290
Query: 2713 -LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G +I W K ++I R +F A G L + + DSG Y CKA N
Sbjct: 9291 QLSCHVQGSEPIRIQWLKAGREIKPSDRC-SFSFASGTAVLELRDVAKADSGDYVCKASN 9349
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
+D V + P V A K ++ R F + +V T
Sbjct: 9350 VAGSDTTKSKVTIKDK-----PAVAPATK-----KAAVDGRLFFVSEPQSIRVVEKTTAT 9399
Query: 2832 LQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQ--GLYTLALSDVTETESGLYTCRAW 2888
++ G P V+W + G+ ++ + RVF+ Q L + D T+T+SGLY C A+
Sbjct: 9400 FIAKVGGDPIPNVKWTK-GK-WRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAF 9457
Query: 2889 SAHGNVDMNAAITV 2902
+ HG ++ N + V
Sbjct: 9458 NEHGEIESNVNLQV 9471
Score = 95.1 bits (226), Expect = 4e-18
Identities = 87/353 (24%), Positives = 151/353 (42%), Gaps = 31/353 (8%)
Query: 2565 DMRHRSKAFSEARSVISEKRTLSRNSTRKPVFSTF-LTDRTAVEGSRVKLTCSVISSSDP 2623
+++H K +A++ +R + S ++P T +G L + +
Sbjct: 5476 EVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEI 5535
Query: 2624 TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
T W+++G L KY+ + D + L++++ DS EY+ V+N+ G S A + V
Sbjct: 5536 TAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINV 5595
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
IPP+FT+ ++ + + + LEC + G I WFKDD++I + +Y+ F
Sbjct: 5596 LDLI----IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYK-F 5650
Query: 2744 YLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRI 2803
D L I DSGTYTC A N +Q + + T +E P V EK
Sbjct: 5651 SFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSG--HLTVKE---PPYFV--EKP-- 5701
Query: 2804 ARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFV 2863
QS + P N + GGT P ++W ++ + + + V+
Sbjct: 5702 --QS-QDVNP---NTRVQLKALVGGT---------APMTIKWFKDNKELHSGAARS-VWK 5745
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIV 2916
+ +L L T+SG Y C+ + G A + V +P KP+ ++
Sbjct: 5746 DDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVL 5798
Score = 95.1 bits (226), Expect = 4e-18
Identities = 97/385 (25%), Positives = 151/385 (39%), Gaps = 56/385 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-R 3097
+S L P P + L G L C + G P VVW+K+ +V +
Sbjct: 7373 ASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFK 7432
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+TS+ FD L I ++ D G Y C+ATN G +
Sbjct: 7433 ITSKH--FDTSLHILNLEASDVGEYHCKATNEVGSDTC---------------------- 7468
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
S V+ PP+F +L D V L V G P V W KD EV+ + +
Sbjct: 7469 -SCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRI 7527
Query: 3218 Q-DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
+ TL++ + G Y +N++G C L V + R P EP+
Sbjct: 7528 SFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP------EPM 7581
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQIELALAAVTTRD 3335
+ G+ + VV P + W++DG L S+ I +++ +++ A ++ D
Sbjct: 7582 -TVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMS--D 7638
Query: 3336 AGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA 3395
G+Y+ N VG+++ + V V RI P P FIRK + A
Sbjct: 7639 KGLYSFEVKNSVGKSNCTVSVHV-------SDRIVP------------PSFIRKLKDVNA 7679
Query: 3396 REGDTVIIECEVVGDPKPDVYWLRD 3420
G +V++EC V G V W +D
Sbjct: 7680 ILGASVVLECRVSGSAPISVGWFQD 7704
Score = 94.3 bits (224), Expect = 7e-18
Identities = 94/354 (26%), Positives = 143/354 (40%), Gaps = 43/354 (12%)
Query: 2591 TRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
T P F L V+ G +L C + S + V W+RN L KYR +D +
Sbjct: 6347 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 6406
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+++ N DS ++ C +N G+ S S + V S PP I +T L
Sbjct: 6407 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPP-----IVET--LKNA 6459
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
E+ LEC + G P ++ W+KD +Q+ S +Y+ + + I N D G Y CKA
Sbjct: 6460 EVSLECELSGTPPFEVVWYKDKRQLRSSKKYK-IASKNFHTSIHILNVDTSDIGEYHCKA 6518
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
+ N G S V K + P F + L V G
Sbjct: 6519 Q------------NEVG-----SDTCVCTVKLK--------EPPRFVSKLNSLTVVAGEP 6553
Query: 2830 IGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAW 2888
LQ I G P V+WL+E V N R+ + + TL + +G Y C+
Sbjct: 6554 AELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQI- 6612
Query: 2889 SAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
G ++ N A +V +PAVIV + + ++VGE + + G P+
Sbjct: 6613 KNDGGMEENMATLMVL------EPAVIVEK-AGPMTVTVGETCTLECKVAGTPE 6659
Score = 94.3 bits (224), Expect = 7e-18
Identities = 78/307 (25%), Positives = 128/307 (41%), Gaps = 32/307 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L+D + G + L + + +VTW ++G + K + LE+LN+
Sbjct: 6919 LSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKR 6978
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ +YSC +ENE G V + ++ PP F + + + L+C++ G
Sbjct: 6979 DAGQYSCEIENEAGR-------DVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAG 7031
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P ++W+K D ++ Y+ Y + V L + DSG YTCKAENS+ T
Sbjct: 7032 TPEITVSWYKGDTKLRPTPEYRT-YFTNNVATLVFNKVNINDSGEYTCKAENSIGT---- 7086
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
S V RI + L P F L D + G + L + G
Sbjct: 7087 -----------ASSKTV----FRIQERQLP---PSFARQLKDIEQTVGLPVTLTCRLNGS 7128
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P +V W R+G + + FV+ + TL + + SG Y+C A + G +A
Sbjct: 7129 APIQVCWYRDGVLLRDDENLQTSFVD-NVATLKILQTDLSHSGQYSCSASNPLGTASSSA 7187
Query: 2899 AITVVQP 2905
+T +P
Sbjct: 7188 RLTAREP 7194
Score = 94.3 bits (224), Expect = 7e-18
Identities = 93/361 (25%), Positives = 143/361 (39%), Gaps = 50/361 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G LTC + G V W ++G + ++ TS + L I ++ G+YSC
Sbjct: 7116 GLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNV-ATLKILQTDLSHSGQYSC 7174
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A+N G AS+ ARL RE P F ++ V A
Sbjct: 7175 SASNPLGTASSSARLTA--------------REPKKS------PFFDIKPVSIDVIAGES 7214
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
C V G+ P +++W KD +E+ L I D G Y A N
Sbjct: 7215 ADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATN 7274
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
+ G C L V + P+F LE +G+ +++ + P + V+W+R+
Sbjct: 7275 DVGKDMCSAQLSVKE------PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRN 7328
Query: 3305 GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQT 3364
L S + M+ + L + + D+G Y C A N VG AS S + V
Sbjct: 7329 DSELHESWKYNMSFINSVAL-LTINEASAEDSGDYICEAHNGVGDASCSTALTV------ 7381
Query: 3365 SEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+ PPV F +KP A +G VI++CE+ G P +V W++D +V
Sbjct: 7382 ---KAPPV-------------FTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQV 7425
Query: 3425 R 3425
R
Sbjct: 7426 R 7426
Score = 91.5 bits (217), Expect = 5e-17
Identities = 88/364 (24%), Positives = 151/364 (41%), Gaps = 36/364 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN-GVLLDNKLKYRKKLVDGLITLE 2652
P F L+D + + G V+L V +V W ++ G ++ R +D + TL+
Sbjct: 7478 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ 7537
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + S+S +Y C ++N+ G SA L V P T + + F
Sbjct: 7538 LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPF-------A 7590
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
LEC + G P WFKD +++ +D ++ ++ + V L I D G Y+ + +NS
Sbjct: 7591 LECVVTGTPELSAKWFKDGRELSADSKHHITFI-NKVASLKIPCAEMSDKGLYSFEVKNS 7649
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
V T V+ VS +V P F L D G ++ L
Sbjct: 7650 VGKSNCTVSVH-------VSDRIVP---------------PSFIRKLKDVNAILGASVVL 7687
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P V W ++G + + F E + TL LS + +++G+YTC A +
Sbjct: 7688 ECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCTLNLSLLEPSDTGIYTCVAANVA 7746
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIP 2951
G+ + +A +TV +P + P + P + + F+ + K E +P
Sbjct: 7747 GSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWF---KGSRELVP 7803
Query: 2952 GEPC 2955
GE C
Sbjct: 7804 GESC 7807
Score = 91.5 bits (217), Expect = 5e-17
Identities = 73/304 (24%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G+ L C V + + + W+++G L K+ ++ + +L++ A SD
Sbjct: 7582 TVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGL 7641
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
YS V+N G + + ++ V +PP+F R ++D + +VLECR+ G
Sbjct: 7642 YSFEVKNSVGKSNCTVSVHVSDRI----VPPSFIRKLKDVNAILGASVVLECRVSGSAPI 7697
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ WF+D +I S + Q+ + ++ VC L + P D+G YTC A N +D+ +
Sbjct: 7698 SVGWFQDGNEIVSGPKCQSSF-SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECS---- 7752
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
V+T ++ P F +V G ++ IRG P +
Sbjct: 7753 ----------AVLTVQEP-----------PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFK 7791
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+W + R + + + +E + L L +V ESG Y+C + G+ + V
Sbjct: 7792 VKWFKGSRELVP-GESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 7850
Query: 2903 VQPS 2906
+P+
Sbjct: 7851 KEPA 7854
Score = 91.1 bits (216), Expect = 6e-17
Identities = 90/384 (23%), Positives = 146/384 (38%), Gaps = 52/384 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
S+S L P P ++ L G +L C ++G P V W K+ E+ +
Sbjct: 8313 SASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRS-GKK 8371
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
F + I +++ D G Y C+ATN G + +A+
Sbjct: 8372 YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA-------------- 8417
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
PP+F +L D V+L + G+ P V W+KD E+V +
Sbjct: 8418 ---------PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWI 8468
Query: 3218 Q-DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
E TL+ + + G Y +N++G C L V + PE
Sbjct: 8469 SYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESI------ 8522
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
K+ GD + V P + W++DG L + ++ L + V D+
Sbjct: 8523 -KVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 8580
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
GVY+ N VG+ S + ++V +D+T VP P F RK + +
Sbjct: 8581 GVYSFEVQNPVGKDSCTASLQV--SDRT-------------VP----PSFTRKLKETNGL 8621
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
G +V++EC+V G P V W +
Sbjct: 8622 SGSSVVMECKVYGSPPISVSWFHE 8645
Score = 89.8 bits (213), Expect = 1e-16
Identities = 92/373 (24%), Positives = 144/373 (38%), Gaps = 57/373 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV L + + G+ L +++G VVW K+ E+ E+ + ++ L
Sbjct: 8419 PRFVKKL-SDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATL 8477
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ + G+Y+C+ N G +A L+V+ T+ E +K GD
Sbjct: 8478 QFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIK-----VTTGD---- 8528
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT---LE 3226
L C V G+P W+KDG+E+ D NKY+ F+ L+
Sbjct: 8529 --------------TCTLECTVAGTPELSTKWFKDGKELTSD---NKYKISFFNKVSGLK 8571
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I D GVY +N G SC L V V P F L+ L G +
Sbjct: 8572 IINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT---VPPSFTRKLKETNGL-SGSSVV 8627
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ V P + V+W+ +G + R+ TL D L + + D+G YTC A+N
Sbjct: 8628 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLT-DNTCALTVNMLEESDSGDYTCIATN- 8685
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
+ G+D+ S P + + P F++KP + G V
Sbjct: 8686 -----------MAGSDECSAP----------LTVREPPSFVQKPDPMDVLTGTNVTFTSI 8724
Query: 3407 VVGDPKPDVYWLR 3419
V G P V W +
Sbjct: 8725 VKGTPPFSVSWFK 8737
Score = 89.0 bits (211), Expect = 3e-16
Identities = 75/312 (24%), Positives = 126/312 (40%), Gaps = 27/312 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L AV G L C V + + ++WY+ L + Y+ + + + +L +
Sbjct: 7947 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 8006
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
SD EYSC +N GA+++SA L + + +PP F R ++D +
Sbjct: 8007 NKVDHSDVGEYSCKADNSVGAVASSAVLVI----KERKLPPFFARKLKDVHETLGFPVAF 8062
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
ECRI G +++W+KD + D Q ++ V L I G Y C A N +
Sbjct: 8063 ECRINGSEPLQVSWYKDGVLLKDDANLQTSFV-HNVATLQILQTDQSHIGQYNCSASNPL 8121
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
T + E +V P +P V D + GT
Sbjct: 8122 GT--ASSSAKLILSEHEVPP--------------FFDLKP----VSVDLALGESGTFKCH 8161
Query: 2834 VEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
V P ++ W ++ R + N ++ + + TL + V + ++G YTC A + G
Sbjct: 8162 V-TGTAPIKITWAKDNREI-RPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 8219
Query: 2894 VDMNAAITVVQP 2905
+A + V +P
Sbjct: 8220 DSCSAHLGVQEP 8231
Score = 88.2 bits (209), Expect = 5e-16
Identities = 75/311 (24%), Positives = 129/311 (41%), Gaps = 35/311 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L V+ S V+L C V + VTW +N + + KY + L +
Sbjct: 5882 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 5941
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
PSD+ EY C V NE G+ S S + A PP+F + I +T + ++
Sbjct: 5942 TKCDPSDTGEYQCIVSNEGGSCSCSTRV-------ALKEPPSFIKKIENTTTVLKSSATF 5994
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ + G P ITW KDD+ + D ++ D V L I + SG YTC+A+N
Sbjct: 5995 QSTVAGSPPISITWLKDDQILDEDDNVYISFV-DSVATLQIRSVDNGHSGRYTCQAKNES 6053
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
++ F ++ E +I ++ V + L+
Sbjct: 6054 GVERCYAF-------------LLVQEPAQIVEKA------------KSVDVTEKDPMTLE 6088
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G P +V+WL++G+ + R + E + + + V + +SG YT + + G
Sbjct: 6089 CVVAGTPELKVKWLKDGKQIVP-SRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFG 6147
Query: 2893 NVDMNAAITVV 2903
+ +A + V+
Sbjct: 6148 SSSCDAYLRVL 6158
Score = 87.8 bits (208), Expect = 6e-16
Identities = 75/308 (24%), Positives = 120/308 (38%), Gaps = 34/308 (11%)
Query: 3052 FVDIL-PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
FV+ L P QL + G+ L C V G P + W N E++E + S F L
Sbjct: 5228 FVEKLEPSQL-LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMS-FVESTAVLR 5285
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ D+ I+D G Y CEA N G S + V+ + P F
Sbjct: 5286 LTDVGIEDSGEYMCEAQNEAG--SDHCSSIVIVKES---------------------PYF 5322
Query: 3171 TMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPT 3230
T + V Y V L +V G+PP +++W+KD + ++ + + +L+I
Sbjct: 5323 TKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKF 5382
Query: 3231 NLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAV 3290
D G Y+ N G+ C + + + P F +E L G A
Sbjct: 5383 VAADAGEYQCRVTNEVGSSICSARVTLRE------PPSFIKKIESTSSL-RGGTAAFQAT 5435
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
++ + VTW +D + MT + + L L+ + + G Y C A N+ G
Sbjct: 5436 LKGSLPITVTWLKDSDEITEDDNIRMTFE-NNVASLYLSGIEVKHDGKYVCQAKNDAGIQ 5494
Query: 3351 STSGKVEV 3358
S + V
Sbjct: 5495 RCSALLSV 5502
Score = 87.4 bits (207), Expect = 8e-16
Identities = 70/241 (29%), Positives = 107/241 (44%), Gaps = 28/241 (11%)
Query: 3109 LTIKDINIDD-EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I +N +D +G Y CEA N GK +T A+L VV +R+A
Sbjct: 4344 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV--------------KRAA------- 4382
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P ++ V + + TC++ +P + W+K G E+ + + + +LEI
Sbjct: 4383 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4442
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
T + D G Y A N G+VSC L V + AY P F + L G +
Sbjct: 4443 LRTQVVDCGEYTCKASNEYGSVSCTATLTVTE---AY-PPTFLSRPKSL-TTFVGKAAKF 4497
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
V P + W +DG L PS ++ D + + L L+ +T +D GVY+C ASN+
Sbjct: 4498 ICTVTGTPVIETIWQKDGAALSPSPNWKIS-DAENKHILELSNLTIQDRGVYSCKASNKF 4556
Query: 3348 G 3348
G
Sbjct: 4557 G 4557
Score = 87.4 bits (207), Expect = 8e-16
Identities = 86/340 (25%), Positives = 138/340 (40%), Gaps = 45/340 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + S VTW++N L R V+ L++ + DS YSC
Sbjct: 4679 GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCE 4738
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N+ G+ S S + + PP+F +++ + +L+C + G +I+W
Sbjct: 4739 AVNDVGSDSCSTEIVIKE-------PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISW 4791
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
FKD KQI S +Y+ F VC L I + D G Y C N V G+
Sbjct: 4792 FKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYECVVANEV------------GK 4838
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWL 2846
++ +++ T F + D G T+ LQ +RG P V W+
Sbjct: 4839 CGCMATHLLKEPPT-------------FVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 4885
Query: 2847 REGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPS 2906
+ G+ V ++ G+ L + DV + G YTC A + G+ + V +
Sbjct: 4886 K-GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE-- 4942
Query: 2907 DLDGKPAVIVGRPEKDILISVGEDINISFRTQGEP--KPK 2944
PA I+ R E I ++ G+ + + G P KPK
Sbjct: 4943 -----PAKIIERAEL-IQVTAGDPATLEYTVAGTPELKPK 4976
Score = 87.0 bits (206), Expect = 1e-15
Identities = 84/312 (26%), Positives = 132/312 (42%), Gaps = 44/312 (14%)
Query: 3048 DRPEFVDILPG---QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
++P+ D+ P QLK L G TA +T + W K+ E+ A R + +
Sbjct: 5699 EKPQSQDVNPNTRVQLKALVGGTAPMT----------IKWFKDNKELHSGAARSVWK-DD 5747
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG 3164
L + D G Y C+ +N G A++ A L V E +K+
Sbjct: 5748 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK------EPPQFIKK-------- 5793
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
P + LR+ Q+T CQ+ G+P +VSWY DG E+ ++ + T
Sbjct: 5794 ---PSPVLVLRNG--QST---TFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 5845
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
+I+ +++ G Y ARN++G SC L V + P F L+P+ + D
Sbjct: 5846 FQISGARVENSGTYVCEARNDAGTASCSIELKVKE------PPTFIRELKPVEVVKYSD- 5898
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + V P VTW ++ +R S++ +T DR L + D G Y C S
Sbjct: 5899 VELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DRVSVFNLHITKCDPSDTGEYQCIVS 5957
Query: 3345 NEVGRASTSGKV 3356
NE G S S +V
Sbjct: 5958 NEGGSCSCSTRV 5969
Score = 87.0 bits (206), Expect = 1e-15
Identities = 89/384 (23%), Positives = 140/384 (36%), Gaps = 54/384 (14%)
Query: 3037 TSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG 3096
T++S + P+F+ L + G++ C + G P V W +G+E+
Sbjct: 5775 TATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQK 5834
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
S +G I +++ G Y CEA N G AS
Sbjct: 5835 HGISFIDGL-ATFQISGARVENSGTYVCEARNDAGTASC--------------------- 5872
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
S E++ PP F L+ V V L C+V G+PP +V+W K+ E+ K+
Sbjct: 5873 --SIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL 5930
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D G Y+ N G+ SC + + + P F +E
Sbjct: 5931 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE------PPSFIKKIENT 5984
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ + + V P + +TW +D L ++ D L + +V +
Sbjct: 5985 TTVLK-SSATFQSTVAGSPPISITWLKDDQILDEDDNVYISF-VDSVATLQIRSVDNGHS 6042
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G YTC A NE SG EP + K +S +
Sbjct: 6043 GRYTCQAKNE------SGVERCYAFLLVQEP----------------AQIVEKAKSVDVT 6080
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
E D + +EC V G P+ V WL+D
Sbjct: 6081 EKDPMTLECVVAGTPELKVKWLKD 6104
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/363 (24%), Positives = 139/363 (38%), Gaps = 52/363 (14%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEV--EEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
G++ L + G V W K+G + E+ +T++ C L I + D G+Y
Sbjct: 6927 GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKT---CILEILNSTKRDAGQY 6983
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
SCE N G+ A ++ + PP F L
Sbjct: 6984 SCEIENEAGRDVCGALVSTLE-----------------------PPYFVTELEPLEAAVG 7020
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
V L CQV G+P VSWYK ++ Y TL N++D G Y A
Sbjct: 7021 DSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 7080
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
N+ G S + + + P F L+ + + G + ++ + + V WY
Sbjct: 7081 ENSIGTASSKTVFRIQE---RQLPPSFARQLKDIEQT-VGLPVTLTCRLNGSAPIQVCWY 7136
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
RDGV LR + T D L + +G Y+C+ASN +G AS+S ++
Sbjct: 7137 RDGVLLRDDEN-LQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL------ 7189
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
EP+ K P F KP S + G++ EC V G + W +D
Sbjct: 7190 TAREPK-------------KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNK 7236
Query: 3423 KVR 3425
++R
Sbjct: 7237 EIR 7239
Score = 87.0 bits (206), Expect = 1e-15
Identities = 91/378 (24%), Positives = 144/378 (38%), Gaps = 55/378 (14%)
Query: 3045 LAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
L P + P +++L G + T ++G P V W K E+ S
Sbjct: 7755 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNIS-LED 7813
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG 3164
F L + ++ + G YSC TN G AS L V +E
Sbjct: 7814 FVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV--------------KE------- 7852
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
P F RL D V+ P+ L G+PP VSW KD + +R + E+
Sbjct: 7853 --PATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI 7910
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--G 3282
LEI + ++D Y N +G C + + + + P + +EPL + G
Sbjct: 7911 LEILESTIEDYAQYSCLIENEAGQDIC-------EALVSVLEPPYF--IEPLEHVEAVIG 7961
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
+ + V+ P + ++WY++ +LR S A ++ L + V D G Y+C
Sbjct: 7962 EPATLQCKVDGTPEIRISWYKEHTKLR-SAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 8020
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVI 3402
A N VG ++S + + E ++P P F RK + G V
Sbjct: 8021 ADNSVGAVASSAVLVI------KERKLP-------------PFFARKLKDVHETLGFPVA 8061
Query: 3403 IECEVVGDPKPDVYWLRD 3420
EC + G V W +D
Sbjct: 8062 FECRINGSEPLQVSWYKD 8079
Score = 86.6 bits (205), Expect = 1e-15
Identities = 77/316 (24%), Positives = 138/316 (43%), Gaps = 40/316 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKY-RKKLVDGLITL 2651
P F T + + GS V L + S+ T+ W++ N L+ Y K+ ++ +L
Sbjct: 5133 PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALES--SL 5190
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
E+ SDS Y+C V N G + SANL V P TF + + L + +
Sbjct: 5191 ELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE-------PATFVEKLEPSQLLKKGDA 5243
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C++ G P KITWF +D++I +++ ++ + L + + EDSG Y C+A+
Sbjct: 5244 TQLACKVTGTPPIKITWFANDREIKESSKHRMSFV-ESTAVLRLTDVGIEDSGEYMCEAQ 5302
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N +D + V I ++S P+F +V + +
Sbjct: 5303 NEAGSDHCSSIV--------------------IVKES-----PYFTKEFKPIEVLKEYDV 5337
Query: 2831 GLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L E+ G P + W ++ ++ R + F++ L +L + ++G Y CR +
Sbjct: 5338 MLLAEVAGTPPFEITWFKD-NTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTN 5396
Query: 2890 AHGNVDMNAAITVVQP 2905
G+ +A +T+ +P
Sbjct: 5397 EVGSSICSARVTLREP 5412
Score = 86.6 bits (205), Expect = 1e-15
Identities = 82/333 (24%), Positives = 141/333 (42%), Gaps = 35/333 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLE 2652
P F + L T V G +L S+ + V W + ++ R V+ + TL+
Sbjct: 6537 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQ 6596
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENEL 2711
A P+++ +Y C ++N+ G A L V P+ P T ++ +T
Sbjct: 6597 FAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIVEKAGP-MTVTVGET-------C 6648
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC++ G P + W+KD K + S +++ F + + L I + +D+GTYT + +N
Sbjct: 6649 TLECKVAGTPELSVEWYKDGKLLTSSQKHK-FSFYNKISSLRILSVERQDAGTYTFQVQN 6707
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
+V T V+ VS V TR R + G VL G +
Sbjct: 6708 NVGKSSCTAVVD-------VSDRAVPPSFTR--------RLKNTGGVL-------GASCI 6745
Query: 2832 LQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ ++ G P V W E + + F + TL L+ + ++ G YTC A +
Sbjct: 6746 LECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCTLQLNSLDSSDMGNYTCVAANV 6804
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G+ + A +TV +P +P + P K++
Sbjct: 6805 AGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNV 6837
Score = 86.2 bits (204), Expect = 2e-15
Identities = 64/197 (32%), Positives = 90/197 (45%), Gaps = 12/197 (6%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKK 2643
TL N+ P L T G + C+VIS P ++WY+ LL K K
Sbjct: 3230 TLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLSTGFKC-KF 3287
Query: 2644 LVDGL-ITLEVLNAVPSDSAEYSCTVENENGAISTSANLK------VYPSFEASPIPPTF 2696
L DG TL ++ A P D+A Y+C +N+ G +TSA+L V P E PP
Sbjct: 3288 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAI 3347
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
++DT +CR+ G L K++W+ DK+I R+ + +L I
Sbjct: 3348 ITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAE 3405
Query: 2757 PTPEDSGTYTCKAENSV 2773
PED GTYT A N+V
Sbjct: 3406 AYPEDEGTYTFVASNAV 3422
Score = 86.2 bits (204), Expect = 2e-15
Identities = 83/339 (24%), Positives = 145/339 (42%), Gaps = 41/339 (12%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L +V + + WY++G L KYR + + L+ +A DS +Y+
Sbjct: 4958 GDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFE 5017
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
+ NE G+ S V I P FT+ +R+ + L+C+I G +++W
Sbjct: 5018 ISNEVGSSSCETTFTVLDR----DIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSW 5073
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
FKD K+I + RY+ ++ +G L I D+G +TC+A NSV + + +
Sbjct: 5074 FKDGKEIAASDRYRIAFV-EGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV--- 5129
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWL 2846
Q P+ VT +P +VL G + L+ +G P + W
Sbjct: 5130 --QEPPSFVT--------------KPGSKDVLP------GSAVCLKSTFQGSTPLTIRWF 5167
Query: 2847 REGRSVTEVYRNARVFVEQGL-YTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ + + V + ++ L +L L V ++SG YTC+ + G V+ +A + V +
Sbjct: 5168 KGNKEL--VSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE- 5224
Query: 2906 SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
PA V + E L+ G+ ++ + G P K
Sbjct: 5225 ------PATFVEKLEPSQLLKKGDATQLACKVTGTPPIK 5257
Score = 85.4 bits (202), Expect = 3e-15
Identities = 91/374 (24%), Positives = 146/374 (39%), Gaps = 58/374 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P F+ L ++++ L C V G P V W+KN E+ +T + + F+
Sbjct: 5882 PTFIRELK-PVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLH 5940
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
+T D + D G Y C +N G S R+A LK PP
Sbjct: 5941 ITKCDPS--DTGEYQCIVSNEGGSCSCSTRVA-------------LKE----------PP 5975
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD--EQFHTLE 3226
F ++ + V GSPP ++W KD + + D+ N Y + TL+
Sbjct: 5976 SFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ--ILDEDDNVYISFVDSVATLQ 6033
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I + G Y A+N SG C+ L+V + P + E D +
Sbjct: 6034 IRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE-------PAQIVEKAKSVDVTEKDPMT 6086
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ VV P + V W +DG ++ PSR M+ + + + +V +D+G YT N+
Sbjct: 6087 LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFE-NNVASFRIQSVMKQDSGQYTFKVEND 6145
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
G +S + V+ DQ IP P F +K + G ++ +EC+
Sbjct: 6146 FGSSSCDAYLRVL--DQ----NIP-------------PSFTKKLTKMDKVLGSSIHMECK 6186
Query: 3407 VVGDPKPDVYWLRD 3420
V G W +D
Sbjct: 6187 VSGSLPISAQWFKD 6200
Score = 84.6 bits (200), Expect = 6e-15
Identities = 82/318 (25%), Positives = 128/318 (40%), Gaps = 40/318 (12%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G C + + V+WY +G + K+ +DGL T ++ A +S Y C
Sbjct: 5803 GQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCE 5862
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N+ G S S LKV PPTF R ++ + +++ LEC + G P ++TW
Sbjct: 5863 ARNDAGTASCSIELKVKE-------PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTW 5915
Query: 2728 FKDDKQIPSDGRYQAFYLAD--GVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
K++++I S +Y L D V L I P D+G Y C N
Sbjct: 5916 LKNNREIRSSKKYT---LTDRVSVFNLHITKCDPSDTGEYQCIVSNE------------- 5959
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVE 2844
G S TR+A + P F + + + Q + G P +
Sbjct: 5960 GGSCSCS--------TRVALK----EPPSFIKKIENTTTVLKSSATFQSTVAGSPPISIT 6007
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++ + + E N + + TL + V SG YTC+A + G A + V +
Sbjct: 6008 WLKDDQILDE-DDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE 6066
Query: 2905 PSDLDGKPAVIVGRPEKD 2922
P+ + K A V EKD
Sbjct: 6067 PAQIVEK-AKSVDVTEKD 6083
Score = 84.6 bits (200), Expect = 6e-15
Identities = 92/388 (23%), Positives = 149/388 (38%), Gaps = 52/388 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
S+S + P P ++ L +L C + G P VVW K+ ++
Sbjct: 6431 STSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKY 6490
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ N F + I +++ D G Y C+A N G +D V KLK
Sbjct: 6491 KIASKN-FHTSIHILNVDTSDIGEYHCKAQNEVG-----------SDTCV--CTVKLKE- 6535
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
PP+F +L V A P L + G+ P V W K+ EEV+ + +
Sbjct: 6536 ---------PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRI 6586
Query: 3218 Q-DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
E TL+ A + G Y +N+ G L+V + P
Sbjct: 6587 TFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV-------LEPAVIVEKAGP 6639
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+ + V P + V WY+DG L S++ + + L + +V +DA
Sbjct: 6640 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 6698
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G YT N VG++S + V+V S+ +P P F R+ +++
Sbjct: 6699 GTYTFQVQNNVGKSSCTAVVDV------SDRAVP-------------PSFTRRLKNTGGV 6739
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
G + I+EC+V G V W + K+
Sbjct: 6740 LGASCILECKVAGSSPISVAWFHEKTKI 6767
Score = 84.2 bits (199), Expect = 7e-15
Identities = 79/327 (24%), Positives = 127/327 (38%), Gaps = 33/327 (10%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
E S S V L + P F+ + +L +A +V G P + W+K+ ++
Sbjct: 5959 EGGSCSCSTRVALK-EPPSFIKKIENTTTVLKS-SATFQSTVAGSPPISITWLKDDQILD 6016
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
E+ S F L I+ ++ GRY+C+A N G YA L V
Sbjct: 6017 EDDNVYIS-FVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLV----------- 6064
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
P Q + + V P+ L C V G+P KV W KDG+++V +
Sbjct: 6065 ------------QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSR 6112
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCC 3271
+ + + I D G Y N+ G+ SC L V+D+ I P F
Sbjct: 6113 YFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNI----PPSFTK 6168
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L + K+ G + + V + W++DG + S + + + + L + +
Sbjct: 6169 KLTKMDKV-LGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC-HERSVSLEVNNL 6226
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEV 3358
D YTC SN G + SG + V
Sbjct: 6227 ELEDTANYTCKVSNVAGDDACSGILTV 6253
Score = 83.8 bits (198), Expect = 1e-14
Identities = 75/310 (24%), Positives = 133/310 (42%), Gaps = 38/310 (12%)
Query: 3042 GVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTS 3100
G+ + P F+ + PG+ + + T +KG P + W K+ +VE +G +
Sbjct: 6249 GILTVKEPPSFL-VKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKD--DVELVSGPKCFI 6305
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA 3160
G L + ++ G+Y+C TN G S L +VT+
Sbjct: 6306 GLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTML-LVTE---------------- 6348
Query: 3161 EVEGDYPPQFTMRLRDRR-VQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQ 3218
PP+F +L + V+A RL C++ GSP +V W+++ E+ DK R +
Sbjct: 6349 ------PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFI 6402
Query: 3219 DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
D +++ + +D G + A+N +G+ SC ++V + P P+ +
Sbjct: 6403 D-SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE-------PPVFSSFPPIVE 6454
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ E+ + + P V WY+D +LR S++ ++ + + V T D G
Sbjct: 6455 TLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKK-YKIASKNFHTSIHILNVDTSDIGE 6513
Query: 3339 YTCTASNEVG 3348
Y C A NEVG
Sbjct: 6514 YHCKAQNEVG 6523
Score = 83.8 bits (198), Expect = 1e-14
Identities = 83/353 (23%), Positives = 137/353 (38%), Gaps = 43/353 (12%)
Query: 2591 TRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
T P F+ L + + GS V + C V S +V+W+ G + + KY+ L D
Sbjct: 8606 TVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L V SDS +Y+C N G+ SA L V PP+F + L
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE-------PPSFVQKPDPMDVLTGTN 8718
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+ ++G P ++WFK ++ R L D V L + + SG YTC
Sbjct: 8719 VTFTSIVKGTPPFSVSWFKGSSELVPGDRCNV-SLEDSVAELELFDVDTSQSGEYTCIVS 8777
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N G+ S + + A + R L DY + +G +
Sbjct: 8778 NE------------AGKASCTTHLYIKAPAKFVKR-------------LNDYSIEKGKPL 8812
Query: 2831 GLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ G P V W + G +VT R + + L + T ++G Y C +
Sbjct: 8813 ILEGTFTGTPPISVTWKKNGINVTPSQR-CNITTTEKSAILEIPSSTVEDAGQYNCYIEN 8871
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
A G +A I +++P P + + + + +SVG+ ++ + G P+
Sbjct: 8872 ASGKDSCSAQILILEP------PYFV--KQLEPVKVSVGDSASLQCQLAGTPE 8916
Score = 83.4 bits (197), Expect = 1e-14
Identities = 82/359 (22%), Positives = 140/359 (38%), Gaps = 53/359 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEGR 3121
L G TA ++KG V W+K+ E+ E+ RMT + N L + I + +G+
Sbjct: 5425 LRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNV--ASLYLSGIEVKHDGK 5482
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C+A N G A L+V T+ E + +GD
Sbjct: 5483 YVCQAKNDAGIQRCSALLSVKEPATITEEAVSID-----VTQGD---------------- 5521
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P L + G+ W+KDG+E+ + + L+I T D G Y
Sbjct: 5522 --PATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE 5579
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G SC + V + + P F L+ + + +G + + +V + + W
Sbjct: 5580 VQNDVGRSSCKARINV---LDLIIPPSFTKKLKKMDSI-KGSFIDLECIVAGSHPISIQW 5635
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++D + S + + D L ++ + D+G YTC+A+N+ G SG + V
Sbjct: 5636 FKDDQEISASEKYKFSF-HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV--- 5691
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
EP P F+ KP+S + V ++ V G + W +D
Sbjct: 5692 ---KEP----------------PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKD 5731
Score = 83.4 bits (197), Expect = 1e-14
Identities = 84/352 (23%), Positives = 142/352 (40%), Gaps = 52/352 (14%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V G P V W+K+G ++ + F I+ + D G+Y+ + N
Sbjct: 6087 LECVVAGTPELKVKWLKDGKQIVPSR-YFSMSFENNVASFRIQSVMKQDSGQYTFKVEND 6145
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G +S A L V+ D+ + PP FT +L + + C
Sbjct: 6146 FGSSSCDAYLRVL-DQNI-------------------PPSFTKKLTKMDKVLGSSIHMEC 6185
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+V GS P W+KDG+E+ + E+ +LE+ L+D Y N +G
Sbjct: 6186 KVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDD 6245
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
+C L V + V P G + + + A+++ P + W++D V L
Sbjct: 6246 ACSGILTVKEPPSFLVKP----GRQ---QAIPDSTVEFKAILKGTPPFKIKWFKDDVELV 6298
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
+ + L+ L L +V G YTC +N+VG S + + V +EP
Sbjct: 6299 SGPKCFIGLEGSTSF-LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLV------TEP-- 6349
Query: 3370 PPVVISPDVPYSKEPMFIRKPRSSE-AREGDTVIIECEVVGDPKPDVYWLRD 3420
P F++K +S+ + GD+ +EC++ G P+ V W R+
Sbjct: 6350 --------------PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRN 6387
Score = 83.4 bits (197), Expect = 1e-14
Identities = 88/361 (24%), Positives = 137/361 (37%), Gaps = 48/361 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+ L + G P V W KNG V R L I ++D G+Y+C
Sbjct: 8809 GKPLILEGTFTGTPPISVTWKKNGINVTPSQ-RCNITTTEKSAILEIPSSTVEDAGQYNC 8867
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
N GK S A++ ++ PP F +L +V
Sbjct: 8868 YIENASGKDSCSAQILILE-----------------------PPYFVKQLEPVKVSVGDS 8904
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L CQ+ G+P VSWYK ++ + TL +++D G Y A N
Sbjct: 8905 ASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAEN 8964
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
+ G VS L V + + P F L + + G + + + V+WY+D
Sbjct: 8965 SVGEVSASTFLTVQE---QKLPPSFSRQLRDVQET-VGLPVVFDCAISGSEPISVSWYKD 9020
Query: 3305 GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQT 3364
G L+ S + T D L + AG Y+CTA+N +G AS+S ++ +
Sbjct: 9021 GKPLKDSPN-VQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL------ 9073
Query: 3365 SEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+E + P P F + +A G++ EC V G V W +D ++
Sbjct: 9074 TEGKNP-------------PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREI 9120
Query: 3425 R 3425
R
Sbjct: 9121 R 9121
Score = 83.0 bits (196), Expect = 2e-14
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F +++ G L+ +VI P + W+ NGVLL Y+ +L +
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEA------------------SPIPPT 2695
L D EY+C N+ G SA LK+ E P PP
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
F + ++ + E + G+P P +TWFK++KQ+ + Y + +G ++
Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3682
Query: 2756 NPTPEDSGTYTCKAEN 2771
+P EDSG Y CKAEN
Sbjct: 3683 DPQREDSGLYICKAEN 3698
Score = 82.6 bits (195), Expect = 2e-14
Identities = 81/320 (25%), Positives = 134/320 (41%), Gaps = 32/320 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F + D A+ G V L +V S +VTW + ++ K + +G+ L +
Sbjct: 4851 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLII 4910
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ S +Y+C ENE G+ ++ L V E + I I+ T A + L
Sbjct: 4911 PDVQISFGGKYTCLAENEAGSQTSVGELIVK---EPAKIIER-AELIQVT---AGDPATL 4963
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E + G P K W+KD + + + +Y+ + + V +L + DSG YT + N V
Sbjct: 4964 EYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDSGQYTFEISNEV 5022
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
+ FT + ++ P F L + GT L
Sbjct: 5023 GSSSCE--TTFTVLDRDIA--------------------PFFTKPLRNVDSVVNGTCRLD 5060
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+I G P RV W ++G+ + R FVE G +L + V ++G +TCRA ++ G
Sbjct: 5061 CKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-GTASLEIIRVDMNDAGNFTCRATNSVG 5119
Query: 2893 NVDMNAAITVVQPSDLDGKP 2912
+ D + A+ V +P KP
Sbjct: 5120 SKDSSGALIVQEPPSFVTKP 5139
Score = 82.6 bits (195), Expect = 2e-14
Identities = 89/376 (23%), Positives = 150/376 (39%), Gaps = 54/376 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F L K+L G + ++ C V G W K+G E+ A + + L
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVSGSLPISAQWFKDGKEISTSA-KYRLVCHERSVSL 6221
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ ++ ++D Y+C+ +N G + L V +E PP
Sbjct: 6222 EVNNLELEDTANYTCKVSNVAGDDACSGILTV--------------KE---------PPS 6258
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F ++ ++ V + G+PP K+ W+KD E+V + + L +
Sbjct: 6259 FLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYS 6318
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ G Y N+ G+ SC L+V + P+F LE + GD R+
Sbjct: 6319 VDASKTGQYTCHVTNDVGSDSCTTMLLVTE------PPKFVKKLEASKIVKAGDSSRLEC 6372
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
+ P + V W+R+ L S + MT D + + ++T D+G + C A N G
Sbjct: 6373 KIAGSPEIRVVWFRNEHELPASDKYRMTFI-DSVAVIQMNNLSTEDSGDFICEAQNPAGS 6431
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
S S KV V + PPV +S P + +++E V +ECE+ G
Sbjct: 6432 TSCSTKVIV---------KEPPV-------FSSFPPIVETLKNAE------VSLECELSG 6469
Query: 3410 DPKPDVYWLRDFLKVR 3425
P +V W +D ++R
Sbjct: 6470 TPPFEVVWYKDKRQLR 6485
Score = 82.2 bits (194), Expect = 3e-14
Identities = 88/358 (24%), Positives = 138/358 (38%), Gaps = 35/358 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITL 2651
KPVF +EG + V+ P W+ +G + N ++ + DG +L
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ A PSDS E++ +N G S S L V + P F +++ ++L
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTV--EAVEHQVKPMFVEKLKNVNIKEGSQL 1573
Query: 2712 VLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
++ R G P P I W K+ D +P G L ID+ +DS YT A
Sbjct: 1574 EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1633
Query: 2771 NSVWTDQITHFVNFTGRESQVSPN---VV---TAEKTRIARQSLE--------------- 2809
N D VN ++ P ++ T IA LE
Sbjct: 1634 NKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGD 1693
Query: 2810 ------SRRPHFGNVLTDYQVARGGTIGLQVEIR--GCPTR-VEWLREGRSVTEVYRNAR 2860
++P F LT ++ R G + + G PT VEWL +G+ + E R
Sbjct: 1694 LYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLR 1752
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G +L +SG+ TCRA + +G +A + V L + + GR
Sbjct: 1753 MINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGR 1810
Score = 82.2 bits (194), Expect = 3e-14
Identities = 90/365 (24%), Positives = 145/365 (39%), Gaps = 58/365 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G+ A L G W K+G E+ + S + L I D
Sbjct: 5515 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSI-LKIISTEKKDS 5573
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-R 3178
G Y+ E N G++S AR+ V+ D + PP FT +L+
Sbjct: 5574 GEYTFEVQNDVGRSSCKARINVL-DLII-------------------PPSFTKKLKKMDS 5613
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
++ ++ + L C V GS P + W+KD +E+ +K + + D LEI+ D G
Sbjct: 5614 IKGSF-IDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF-LEISQLEGTDSGT 5671
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
Y +A N +G C L V + P + ++ +++ A+V +
Sbjct: 5672 YTCSATNKAGHNQCSGHLTVKE-------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPM 5724
Query: 3298 GVTWYRDGVRLRP-SRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W++D L + R++ D +EL A T D+G Y C SN+VG A++ +
Sbjct: 5725 TIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKAT--DSGTYICQLSNDVGTATSKATL 5782
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS-SEAREGDTVIIECEVVGDPKPDV 3415
V EP P FI+KP R G + EC++ G PK V
Sbjct: 5783 FV------KEP----------------PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRV 5820
Query: 3416 YWLRD 3420
W D
Sbjct: 5821 SWYLD 5825
Score = 82.2 bits (194), Expect = 3e-14
Identities = 75/320 (23%), Positives = 127/320 (39%), Gaps = 35/320 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D + GS + L + + +V+W ++ L+ + + + LE+L +
Sbjct: 7860 LADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIE 7919
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D A+YSC +ENE G A + V PP F + + L+C++ G
Sbjct: 7920 DYAQYSCLIENEAGQDICEALVSVLE-------PPYFIEPLEHVEAVIGEPATLQCKVDG 7972
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P +I+W+K+ ++ S Y+ + V L I+ D G Y+CKA+NSV
Sbjct: 7973 TPEIRISWYKEHTKLRSAPAYK-MQFKNNVASLVINKVDHSDVGEYSCKADNSV------ 8025
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V+ + V K R P F L D G + + I G
Sbjct: 8026 ---------GAVASSAVLVIKER-------KLPPFFARKLKDVHETLGFPVAFECRINGS 8069
Query: 2840 -PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P +V W ++G + + FV + TL + ++ G Y C A + G +A
Sbjct: 8070 EPLQVSWYKDGVLLKDDANLQTSFV-HNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 8128
Query: 2899 AITVVQ---PSDLDGKPAVI 2915
+ + + P D KP +
Sbjct: 8129 KLILSEHEVPPFFDLKPVSV 8148
Score = 81.8 bits (193), Expect = 4e-14
Identities = 97/413 (23%), Positives = 156/413 (37%), Gaps = 59/413 (14%)
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
F + L +Y F ++ N G T + + +A P F L ++ G T
Sbjct: 5003 FYSAELHDSGQYTFEIS--NEVGSSSCETTFTVLDRDIA---PFFTKPLRNVDSVVNG-T 5056
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L C + G V W K+G E+ + R F L I ++++D G ++C AT
Sbjct: 5057 CRLDCKIAGSLPMRVSWFKDGKEIAA-SDRYRIAFVEGTASLEIIRVDMNDAGNFTCRAT 5115
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N+ G + L V PP F + + V V L
Sbjct: 5116 NSVGSKDSSGALIV-----------------------QEPPSFVTKPGSKDVLPGSAVCL 5152
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
GS P + W+K +E+V ++ +LE+ D G Y N +G
Sbjct: 5153 KSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 5212
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
V C L V + F LEP L +GD +++ V P + +TW+ +
Sbjct: 5213 GVECSANLFVKE------PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDRE 5266
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
++ S + M+ + L L V D+G Y C A NE G+D S
Sbjct: 5267 IKESSKHRMSFVESTAV-LRLTDVGIEDSGEYMCEAQNEA------------GSDHCSS- 5312
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+VI + PY F ++ + E + V++ EV G P ++ W +D
Sbjct: 5313 ----IVIVKESPY-----FTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKD 5356
Score = 81.8 bits (193), Expect = 4e-14
Identities = 93/376 (24%), Positives = 142/376 (37%), Gaps = 55/376 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L IL G + L C V G V W ++G+E+ + S F+ C L
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVSGSAPISVGWFQDGNEIVS-GPKCQSSFSENVCTL 7725
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ + D G Y+C A N G A L TV E PP
Sbjct: 7726 NLSLLEPSDTGIYTCVAANVAGSDECSAVL------TVQE-----------------PPS 7762
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
F V + T + G+PP KV W+K E+V + N ++ LE+
Sbjct: 7763 FEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFE 7822
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ G Y N++G+ SC L V + F L + + G + + A
Sbjct: 7823 VQPLESGDYSCLVTNDAGSASCTTHLFVKE------PATFVKRLAD-FSVETGSPIVLEA 7875
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
P + V+W +D + S R +T+ I L + T D Y+C NE G+
Sbjct: 7876 TYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI-LEILESTIEDYAQYSCLIENEAGQ 7934
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
V V+ EP PY EP+ EA G+ ++C+V G
Sbjct: 7935 DICEALVSVL------EP-----------PYFIEPL-----EHVEAVIGEPATLQCKVDG 7972
Query: 3410 DPKPDVYWLRDFLKVR 3425
P+ + W ++ K+R
Sbjct: 7973 TPEIRISWYKEHTKLR 7988
Score = 81.0 bits (191), Expect = 7e-14
Identities = 74/311 (23%), Positives = 118/311 (37%), Gaps = 35/311 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L V G+ L C V + ++W+++ + + KYR L+ LE+
Sbjct: 4758 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 4817
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ +D EY C V NE G A PPTF + + D L + L
Sbjct: 4818 FSFNSADVGEYECVVANEVGKCGCMAT-------HLLKEPPTFVKKVDDLIALGGQTVTL 4870
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ +RG +TW K + I DG+ + + ++GV L I + G YTC AEN
Sbjct: 4871 QAAVRGSEPISVTWMKGQEVIREDGKIKMSF-SNGVAVLIIPDVQISFGGKYTCLAENE- 4928
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
G ++ V +V I R L QV G L+
Sbjct: 4929 -----------AGSQTSVGELIVKEPAKIIERAEL-------------IQVTAGDPATLE 4964
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G P + +W ++GR + + R+ + + L +SG YT + G
Sbjct: 4965 YTVAGTPELKPKWYKDGRPLV-ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 5023
Query: 2893 NVDMNAAITVV 2903
+ TV+
Sbjct: 5024 SSSCETTFTVL 5034
Score = 80.6 bits (190), Expect = 9e-14
Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 9/185 (4%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG+ ++D N VSL+W K + + +L Y VE + +G +W +
Sbjct: 22979 PGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVE---MQTKGSDKWATCATVKVTEATI 23035
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDILPGQLKILAGETA 3068
L QGEEY FRV+ +N G + Q S + +A D P +L +LAGE
Sbjct: 23036 TGLIQGEEYSFRVSAQNEKGISDPRQLSVPV---IAKDLVIPPAFKLLFNTFTVLAGEDL 23092
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
+ G+P P V W K+ +++ R+ ++ + LTIKD +D G Y + TN
Sbjct: 23093 KVDVPFIGRPTPAVTWHKDNVPLKQTT-RVNAESTENNSLLTIKDACREDVGHYVVKLTN 23151
Query: 3129 THGKA 3133
+ G+A
Sbjct: 23152 SAGEA 23156
Score = 80.2 bits (189), Expect = 1e-13
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 10/196 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P +D ++L W + ++ Y +E +G RWV T ++ +
Sbjct: 28785 PGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEK----RQGNERWVRCNFTDVSECQY 28840
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ---LKILAG 3065
L G+ Y FR+ RN G SS I + + P V+ P L I +G
Sbjct: 28841 TVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSG 28900
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
E+ + V+G+PVP V W K+G E+E+ + G L ++D D G Y+ E
Sbjct: 28901 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLG-STSLFVRDATRDHRGVYTVE 28959
Query: 3126 ATNTHGKASTYARLAV 3141
A N G A ++ V
Sbjct: 28960 AKNASGSAKAEIKVKV 28975
Score = 79.8 bits (188), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 79.8 bits (188), Expect = 2e-13
Identities = 68/306 (22%), Positives = 127/306 (41%), Gaps = 32/306 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D + +G + L + + +VTW +NG+ + + + LE+ ++
Sbjct: 8801 LNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVE 8860
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ +Y+C +EN +G S SA + + PP F + + + L+C++ G
Sbjct: 8861 DAGQYNCYIENASGKDSCSAQILILE-------PPYFVKQLEPVKVSVGDSASLQCQLAG 8913
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P ++W+K D ++ Y+ + + V L + DSG Y CKAENSV +
Sbjct: 8914 TPEIGVSWYKGDTKLRPTTTYK-MHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAS 8972
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
F+ T +E ++ P+ F L D Q G + I G
Sbjct: 8973 TFL--TVQEQKLPPS--------------------FSRQLRDVQETVGLPVVFDCAISGS 9010
Query: 2840 -PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P V W ++G+ + + N + TL + + +G Y+C A + G+ +A
Sbjct: 9011 EPISVSWYKDGKPLKD-SPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSA 9069
Query: 2899 AITVVQ 2904
+ + +
Sbjct: 9070 RLILTE 9075
Score = 79.4 bits (187), Expect = 2e-13
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD- 3211
+L+ +++E Y P F ++ + R +V+G P P+ W+ DG+++V D
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 3212 KRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC 3271
+ +++ +L I P D G + V A+N +G S L V+ + V P F
Sbjct: 1502 THKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE-AVEHQVKPMFVE 1560
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD-RDGQIELALAA 3330
L+ + + EG +L + P+ + W ++ + P + + ++ G+ L + +
Sbjct: 1561 KLKNV-NIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1619
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEV 3358
++D+ YT TA N+ GR +T KV V
Sbjct: 1620 TVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 79.4 bits (187), Expect = 2e-13
Identities = 76/323 (23%), Positives = 131/323 (40%), Gaps = 34/323 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ LT V GS + + C V S + W+++G + KYR + ++LEV
Sbjct: 6164 PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEV 6223
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
N D+A Y+C V N G + S L V PP+F + ++ +
Sbjct: 6224 NNLELEDTANYTCKVSNVAGDDACSGILTVKE-------PPSFLVKPGRQQAIPDSTVEF 6276
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ ++G P KI WFKDD ++ S G L L + + +G YTC N V
Sbjct: 6277 KAILKGTPPFKIKWFKDDVELVS-GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDV 6335
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
+D T + T + V E ++I + SR L+
Sbjct: 6336 GSDSCTTMLLVT----EPPKFVKKLEASKIVKAGDSSR--------------------LE 6371
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+I G P RV W R + + F++ + + +++++ +SG + C A + G
Sbjct: 6372 CKIAGSPEIRVVWFRNEHELPASDKYRMTFID-SVAVIQMNNLSTEDSGDFICEAQNPAG 6430
Query: 2893 NVDMNAAITVVQPSDLDGKPAVI 2915
+ + + V +P P ++
Sbjct: 6431 STSCSTKVIVKEPPVFSSFPPIV 6453
Score = 79.4 bits (187), Expect = 2e-13
Identities = 97/370 (26%), Positives = 138/370 (37%), Gaps = 51/370 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P FV L L ++AGE A L S++G V W+K EV E+ + F L
Sbjct: 6537 PRFVSKL-NSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATL 6595
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ G+Y C+ N G A L V+ E + VE P
Sbjct: 6596 QFAKAEPANAGKYICQIKNDGGMEENMATLMVL--------------EPAVIVEKAGPMT 6641
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
T V T L C+V G+P V WYKDG+ + ++ + +L I
Sbjct: 6642 VT-------VGET--CTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILS 6692
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
D G Y +NN G SC VVD RA V P F L+ + G +
Sbjct: 6693 VERQDAGTYTFQVQNNVGKSSCTA--VVDVSDRA-VPPSFTRRLKNTGGV-LGASCILEC 6748
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
V + V W+ + ++ S T D L L ++ + D G YTC A+N
Sbjct: 6749 KVAGSSPISVAWFHEKTKI-VSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAAN---- 6803
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
V G+D+ V++ P P F+++P E G V + G
Sbjct: 6804 --------VAGSDECR------AVLTVQEP----PSFVKEPEPLEVLPGKNVTFTSVIRG 6845
Query: 3410 DPKPDVYWLR 3419
P V W R
Sbjct: 6846 TPPFKVNWFR 6855
Score = 78.6 bits (185), Expect = 4e-13
Identities = 60/190 (31%), Positives = 87/190 (45%), Gaps = 10/190 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N V+L W K + + Y VE + +G RW++ T + F
Sbjct: 25533 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDL-PDG--RWMKASFTNVLETEF 25589
Query: 3009 DAFNLKQGEEYHFRVTPRNRYG-WGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL---A 3064
L + + Y FRV RN G + E S +S +I D P + P ++ A
Sbjct: 25590 TVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN-ASLDPKYKDVIVVHA 25648
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L ++GKP+P VVW K+G E+EE A RM + L +KD D G+Y
Sbjct: 25649 GETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYIL 25708
Query: 3125 EATNTHGKAS 3134
+ +N G S
Sbjct: 25709 KLSNVGGTKS 25718
Score = 77.8 bits (183), Expect = 6e-13
Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 14/217 (6%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDE 3220
V PPQ L+ VQ+ P R + G P PK+SWYK+ E+++ + K+ D
Sbjct: 3233 VNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDG 3291
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP---LY 3277
Q +TL + +D VY A+N+ G + L V+ + V+P+ + P +
Sbjct: 3292 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE--VPEVVSPDQEMPVYPPAIIT 3349
Query: 3278 KLH-----EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L EG R V + V+WY +++PSR MT D +L +A
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAY 3407
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
D G YT ASN VG+ S++ + + + RI
Sbjct: 3408 PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444
Score = 77.4 bits (182), Expect = 9e-13
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 77.4 bits (182), Expect = 9e-13
Identities = 81/366 (22%), Positives = 142/366 (38%), Gaps = 42/366 (11%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
++ S K T+ + + PV + G K TC + S+ + W++ G +
Sbjct: 4368 KTATSAKLTVVKRAA--PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE 4425
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
K + + +LE+L D EY+C NE G++S +A L V ++ PPTF
Sbjct: 4426 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY-----PPTF 4480
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
+ C + G P+ + W KD + ++ A+ L + N
Sbjct: 4481 LSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWK-ISDAENKHILELSN 4539
Query: 2757 PTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG 2816
T +D G Y+CKA N D + AE I +PHF
Sbjct: 4540 LTIQDRGVYSCKASNKFGAD------------------ICQAELIII-------DKPHFI 4574
Query: 2817 NVLTDYQVARGGTIGLQVEI-RGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDV 2875
L Q A + L+ ++ V W ++G+ + ++ ++ E + TL +
Sbjct: 4575 KELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPP-GKDYKICFEDKIATLEIPLA 4633
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISF 2935
+SG Y C A + G+ +A +TV +P V + + L+ GE +
Sbjct: 4634 KLKDSGTYVCTASNEAGSSSCSATVTVREPPS-------FVKKVDPSYLMLPGESARLHC 4686
Query: 2936 RTQGEP 2941
+ +G P
Sbjct: 4687 KLKGSP 4692
Score = 77.4 bits (182), Expect = 9e-13
Identities = 89/370 (24%), Positives = 146/370 (39%), Gaps = 58/370 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+++ AG+ A L +V G P W K+G + S F L + D
Sbjct: 4953 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRIS-FKNNVAQLKFYSAELHDS 5011
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y+ E +N G +S V+ DR D P FT LR+
Sbjct: 5012 GQYTFEISNEVGSSSCETTFTVL-DR-------------------DIAPFFTKPLRNVDS 5051
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL C++ GS P +VSW+KDG+E+ R E +LEI +++D G +
Sbjct: 5052 VVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFT 5111
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEAYPSVG 3298
A N+ G+ L+V + P F +P K + G + + + + +
Sbjct: 5112 CRATNSVGSKDSSGALIVQE------PPSFV--TKPGSKDVLPGSAVCLKSTFQGSTPLT 5163
Query: 3299 VTWYRDGVRLRPSRRAIMTLDR-DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W++ L +T + + +EL L V T D+G YTC SN G S +
Sbjct: 5164 IRWFKGNKELVSGGSCYITKEALESSLELYL--VKTSDSGTYTCKVSNVAGGVECSANL- 5220
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEP-MFIRKPRSSE-AREGDTVIIECEVVGDPKPDV 3415
+ KEP F+ K S+ ++GD + C+V G P +
Sbjct: 5221 ----------------------FVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKI 5258
Query: 3416 YWLRDFLKVR 3425
W + +++
Sbjct: 5259 TWFANDREIK 5268
Score = 77.4 bits (182), Expect = 9e-13
Identities = 60/211 (28%), Positives = 94/211 (44%), Gaps = 8/211 (3%)
Query: 2935 FRTQGEPKPKAVPERIPGEPC--VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAE 2992
F +PK P PG P V D + + L W ++ Y V+ L+G
Sbjct: 15914 FSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 15973
Query: 2993 GGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF 3052
+R E I + + +++G +Y RV+ N G G +T + V + P
Sbjct: 15974 EWSRCTEKMIK-VRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQP-VTVAEPQEPPAV 16031
Query: 3053 -VDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
+D+ + G ++I+AG+T + V G+PVP VW K E++++ R+ G L
Sbjct: 16032 ELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD--RVVIDNVGTKSELI 16089
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
IKD D GRY ATN+ G AR+ V
Sbjct: 16090 IKDALRKDHGRYVITATNSCGSKFAAARVEV 16120
Score = 77.0 bits (181), Expect = 1e-12
Identities = 77/336 (22%), Positives = 128/336 (38%), Gaps = 35/336 (10%)
Query: 2571 KAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN 2630
KA +E SV S TL+ P F + T G K C+V + W ++
Sbjct: 4456 KASNEYGSV-SCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKD 4514
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
G L ++ + LE+ N D YSC N+ GA A L +
Sbjct: 4515 GAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK---- 4570
Query: 2691 PIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC 2750
P F + + ++ LEC++ +TW KD +++P Y+ + D +
Sbjct: 4571 ---PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIA 4626
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLES 2810
L I +DSGTY C A N + S S V E ++
Sbjct: 4627 TLEIPLAKLKDSGTYVCTASNEAGS-------------SSCSATVTVREPPSFVKK---- 4669
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYT 2869
V Y + G + L +++G P +V W + + ++E R++
Sbjct: 4670 -------VDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSE-SNTVRMYFVNSEAI 4721
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
L ++DV +SG Y+C A + G+ + I + +P
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 4757
Score = 76.6 bits (180), Expect = 1e-12
Identities = 86/354 (24%), Positives = 134/354 (37%), Gaps = 39/354 (11%)
Query: 3007 SFDAFNLKQGE--EYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
S NL+ + EYH + T N G S S S+ + P FV L L
Sbjct: 7441 SLHILNLEASDVGEYHCKAT--NEVG---SDTCSCSVKFK---EPPRFVKKL-SDTSTLI 7491
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+ L V+G VVW+K+ EV E+ F L + + G+Y C
Sbjct: 7492 GDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYIC 7551
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+ N G A L V+ + E K E G+ P
Sbjct: 7552 QIKNDAGMRECSAVLTVLEPARIIE-----KPEPMTVTTGN------------------P 7588
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C V G+P W+KDG E+ D + + + +L+I + D G+Y +N
Sbjct: 7589 FALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKN 7648
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
+ G +C + V I V P F L+ + + G + + V + V W++D
Sbjct: 7649 SVGKSNCTVSVHVSDRI---VPPSFIRKLKDVNAI-LGASVVLECRVSGSAPISVGWFQD 7704
Query: 3305 GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G + + + + L L+ + D G+YTC A+N G S + V
Sbjct: 7705 GNEIVSGPKCQSSFS-ENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 7757
Score = 76.6 bits (180), Expect = 1e-12
Identities = 61/219 (27%), Positives = 99/219 (45%), Gaps = 15/219 (6%)
Query: 2946 VPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP- 3004
+P PG+P V+D + VSL W + + ++ Y VE+ + G +WV P
Sbjct: 20115 MPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP---GDKWVRCNTAPH 20171
Query: 3005 ---LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI---LPG 3058
+ A L++ +Y FR R S+ S + + LA + P +D+ +
Sbjct: 20172 QIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTI-LAENVPPRIDLSVAMKS 20230
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINID 3117
L + AG L +V GKP+P V W K+G ++ G +M Q N C L + +N
Sbjct: 20231 LLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN--LCTLELFSVNRK 20288
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
D G Y+ A N+ G S +L V+ D+ A K+ +
Sbjct: 20289 DSGDYTITAENSSGSKSATIKLKVL-DKPGPPASVKINK 20326
Score = 75.8 bits (178), Expect = 3e-12
Identities = 79/348 (22%), Positives = 143/348 (41%), Gaps = 41/348 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PVF+ + A++GS V L C + + V W ++ + N K++ +L +
Sbjct: 7385 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI 7444
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
LN SD EY C NE G+ + S ++K F+ PP F + + DT L + + L
Sbjct: 7445 LNLEASDVGEYHCKATNEVGSDTCSCSVK----FKE---PPRFVKKLSDTSTLIGDAVEL 7497
Query: 2714 ECRIRG-QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ G QP+ + W KD ++ + D + L + +P +SG Y C+ +N
Sbjct: 7498 RAIVEGFQPI-SVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKND 7556
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ S + E RI +E P V G L
Sbjct: 7557 AGM-------------RECSAVLTVLEPARI----IEKPEP--------MTVTTGNPFAL 7591
Query: 2833 QVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P +W ++GR ++ ++ F+ + + +L + ++ GLY+ ++
Sbjct: 7592 ECVVTGTPELSAKWFKDGRELSADSKHHITFINK-VASLKIPCAEMSDKGLYSFEVKNSV 7650
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQG 2939
G + ++ V SD P+ I R KD+ +G + + R G
Sbjct: 7651 GKSNCTVSVHV---SDRIVPPSFI--RKLKDVNAILGASVVLECRVSG 7693
Score = 75.4 bits (177), Expect = 3e-12
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 5/170 (2%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E + L C V + + V W ++G + + + + + + + + DS +Y+
Sbjct: 6081 EKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTF 6140
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
VEN+ G+ S A L+V IPP+FT+ + + + + +EC++ G
Sbjct: 6141 KVENDFGSSSCDAYLRVLDQ----NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQ 6196
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
WFKD K+I + +Y+ V L ++N ED+ YTCK N D
Sbjct: 6197 WFKDGKEISTSAKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDD 6245
Score = 74.9 bits (176), Expect = 5e-12
Identities = 81/360 (22%), Positives = 140/360 (38%), Gaps = 40/360 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L + V G+ L C V SS +V W+ + + KY+ D + TL++
Sbjct: 6727 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 6786
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ SD Y+C N G+ A L V PP+F + L +
Sbjct: 6787 NSLDSSDMGNYTCVAANVAGSDECRAVLTVQE-------PPSFVKEPEPLEVLPGKNVTF 6839
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
IRG P K+ WF+ +++ R Y D V L + N SG YTC N+
Sbjct: 6840 TSVIRGTPPFKVNWFRGARELVKGDRCN-IYFEDTVAELELFNIDISQSGEYTCVVSNN- 6897
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
G+ S + V + R S D+ V G +I L+
Sbjct: 6898 -----------AGQASCTTRLFVKEPAAFLKRLS-------------DHSVEPGKSIILE 6933
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G P V W ++G ++T + + L + + T+ ++G Y+C + G
Sbjct: 6934 STYTGTLPISVTWKKDGFNIT-TSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAG 6992
Query: 2893 NVDMNAAITVVQP----SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPE 2948
A ++ ++P ++L+ A + ++ +I +S+ +G+ K + PE
Sbjct: 6993 RDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSW-YKGDTKLRPTPE 7051
Score = 74.5 bits (175), Expect = 6e-12
Identities = 92/369 (24%), Positives = 141/369 (38%), Gaps = 18/369 (4%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++S T G G P F+ P K++ G + C V G P P V W K+G +
Sbjct: 1066 DTSLTEEQAGPGEPA-APYFIT-KPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1123
Query: 3093 EEAGRMTSQFNGF--DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
R +N +C L I DD G Y+ N HG+ S A L + EA
Sbjct: 1124 T-GYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-------LEEA 1175
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +L + E+ Y Q T +++ +V T P + + + + +
Sbjct: 1176 DYELLMKSQQEML--YQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEV-TARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R +D++FH + + + T + VD V F
Sbjct: 1234 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1293
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
++ Y++ EG + + YP + WY+DG R++ R M +DG+ L +
Sbjct: 1294 DLRIKN-YRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI-R 3388
V D G+YT ASN G A SGK+ V P P + S P + R
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412
Query: 3389 KP-RSSEAR 3396
P R S AR
Sbjct: 1413 SPIRMSPAR 1421
Score = 74.5 bits (175), Expect = 6e-12
Identities = 57/184 (30%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 3201 WYKDGEEVVYD-KRRNKYQDEQ-FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
WYKDG E+ + + R+KY E+ H + I+ T D G Y A N +V+ +
Sbjct: 3179 WYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLY------ 3232
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ A P+ L+P+ + G R AV+ P ++WY++ L +
Sbjct: 3233 --VNAPEPPQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL- 3288
Query: 3319 DRDGQ-IELALAAVTTRDAGVYTCTASNEVGRASTSGKV-----EVIGTDQTSEPRIPPV 3372
DGQ L L DA VYTC A N+ G A+TS + EV+ DQ P PP
Sbjct: 3289 -HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPA 3346
Query: 3373 VISP 3376
+I+P
Sbjct: 3347 IITP 3350
Score = 74.5 bits (175), Expect = 6e-12
Identities = 75/315 (23%), Positives = 128/315 (40%), Gaps = 37/315 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L + +V +L C + S V+W+++G + +YR V+G +LE+
Sbjct: 5040 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEI 5099
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ +D+ ++C N G+ +S L V PP+F L + + L
Sbjct: 5100 IRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------PPSFVTKPGSKDVLPGSAVCL 5152
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV-CRLAIDNPTPEDSGTYTCKAENS 2772
+ +G I WFK +K++ S G + + + L + DSGTYTCK N
Sbjct: 5153 KSTFQGSTPLTIRWFKGNKELVSGG--SCYITKEALESSLELYLVKTSDSGTYTCKVSN- 5209
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ S N+ E +E P + +G L
Sbjct: 5210 ------------VAGGVECSANLFVKEPATF----VEKLEP-------SQLLKKGDATQL 5246
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
++ G P ++ W R + E ++ FVE L L+DV +SG Y C A +
Sbjct: 5247 ACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYMCEAQNEA 5305
Query: 2892 GNVDMNAAITVVQPS 2906
G+ D ++I +V+ S
Sbjct: 5306 GS-DHCSSIVIVKES 5319
Score = 74.1 bits (174), Expect = 8e-12
Identities = 58/231 (25%), Positives = 97/231 (41%), Gaps = 24/231 (10%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PPT +++ + + LEC I G P P +TW+++D QI S +Q + G+ RL
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 1000
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFV------NFTGRESQVSPNVVTAEKTRIARQ 2806
I EDSG +TC A N T + ++ F + V+ T EK + +
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 2807 SL---------------ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
+ E P+F ++ GG++ ++ G P V W + G
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 2851 SVTEVYRNARVFVEQ-GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+T YR + +Q G L +S ++G YT + HG +A++
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 74.1 bits (174), Expect = 8e-12
Identities = 60/229 (26%), Positives = 94/229 (41%), Gaps = 7/229 (3%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
ES S+ G P F+ + I G+ A L+ +V G P P + W NG +
Sbjct: 3486 ESPVYSTKFDSEKEGTGPIFIKEV-SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLT 3544
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
A F+G D L I ++DEG Y+C A+N +GK A L + + D
Sbjct: 3545 PSAD-YKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-NSKGEGHKDT 3602
Query: 3153 KLKRERSAEVE---GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVV 3209
+ + + +E G PP F L+ R P V+G P P V+W+K+ +++
Sbjct: 3603 ETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLC 3662
Query: 3210 YDKRRN-KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ T + +D G+Y A N G +C L+V
Sbjct: 3663 TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3711
Score = 72.5 bits (170), Expect = 2e-11
Identities = 84/350 (24%), Positives = 137/350 (39%), Gaps = 43/350 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F L D A+ G+ V L C V S+ +V W+++G + + K + + + TL +
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 7727
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
PSD+ Y+C N G+ SA L V PP+F ++ L L
Sbjct: 7728 SLLEPSDTGIYTCVAANVAGSDECSAVLTVQE-------PPSFEQTPDSVEVLPGMSLTF 7780
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
IRG P K+ WFK +++ G L D V L + P +SG Y+C N
Sbjct: 7781 TSVIRGTPPFKVKWFKGSREL-VPGESCNISLEDFVTELELFEVQPLESGDYSCLVTND- 7838
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
G S + V T + R L D+ V G I L+
Sbjct: 7839 -----------AGSASCTTHLFVKEPATFVKR-------------LADFSVETGSPIVLE 7874
Query: 2834 VEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G P V W+++ +++ R + E+ L + + T + Y+C + G
Sbjct: 7875 ATYTGTPPISVSWIKDEYLISQSERCSITMTEKST-ILEILESTIEDYAQYSCLIENEAG 7933
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
A ++V++P P I P + + +GE + + G P+
Sbjct: 7934 QDICEALVSVLEP------PYFI--EPLEHVEAVIGEPATLQCKVDGTPE 7975
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 72.1 bits (169), Expect = 3e-11
Identities = 81/315 (25%), Positives = 121/315 (38%), Gaps = 37/315 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P F+ L I+ G A L C V G + W K+ ++ R+ SQ + C
Sbjct: 4758 PSFIKTLE-PADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV--C 4814
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I N D G Y C N GK A L +E PP
Sbjct: 4815 LEIFSFNSADVGEYECVVANEVGKCGCMA--------------THLLKE---------PP 4851
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
F ++ D V L V GS P V+W K G+EV+ + + K + I
Sbjct: 4852 TFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMK-GQEVIREDGKIKMSFSNGVAVLII 4910
Query: 3229 P-TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
P + GG Y A N +G+ + L+V + + E L ++ GD +
Sbjct: 4911 PDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAE-------LIQVTAGDPATL 4963
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
V P + WY+DG L S++ ++ ++ +L + D+G YT SNEV
Sbjct: 4964 EYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDSGQYTFEISNEV 5022
Query: 3348 GRASTSGKVEVIGTD 3362
G +S V+ D
Sbjct: 5023 GSSSCETTFTVLDRD 5037
Score = 71.3 bits (167), Expect = 6e-11
Identities = 88/314 (28%), Positives = 138/314 (43%), Gaps = 31/314 (9%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAW--PKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
K K P PG+P V D N +++W PKSD +P+ Y +E E +WV
Sbjct: 18625 KHKFSPPSPPGKPVVTDITENAATVSWTLPKSD--GGSPITGYYMER----REVTGKWVR 18678
Query: 3000 LGITPLN--SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP 3057
+ TP+ F L +G Y FRV N G + S +S I +P I P
Sbjct: 18679 VNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPI-KACRPIKPPGPPINP 18737
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDINI 3116
+LK + ETA+L V KP+ G+ VE ++ G T+Q+N IN
Sbjct: 18738 -KLKDKSRETADL---VWTKPLSDGGSPILGYVVECQKPG--TAQWN---------RINK 18782
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+ R + + Y R + V E + + E + +PP+ + +
Sbjct: 18783 DELIRQCAFRVPGLIEGNEY-RFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTC 18841
Query: 3177 R---RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
R V+ +R+ +V G P P ++W K+G+ +V +KR + QD L+I
Sbjct: 18842 RDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA 18901
Query: 3234 DGGVYEVTARNNSG 3247
D G Y ++A+N+SG
Sbjct: 18902 DHGKYIISAKNSSG 18915
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 11/198 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N V+L W K + + Y VE + EG RW++ T + F
Sbjct: 23369 PGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKEL-PEG--RWMKASFTNIIDTHF 23425
Query: 3009 DAFNLKQGEEYHFRVTPRNRYG-WGESSQTSSSIGVGLAGDRPEFVDILP---GQLKILA 3064
+ L + Y FRV RN G + E S+++ +I D P + + P + + A
Sbjct: 23426 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR-ISMDPKYKDTIVVHA 23484
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE+ + + GKP+P + W+K E+ A R+ + F L++KD D G Y
Sbjct: 23485 GESFKVDADIYGKPIPTIQWIKGDQELSNTA-RLEIKSTDFATSLSVKDAVRVDSGNYIL 23543
Query: 3125 EATNTHGKASTYARLAVV 3142
+A N G+ S + V+
Sbjct: 23544 KAKNVAGERSVTVNVKVL 23561
Score = 70.5 bits (165), Expect = 1e-10
Identities = 56/196 (28%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 2951 PGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS 3007
PGEP + D G +V L W + D +P L+Y VE L G++ R V G
Sbjct: 19028 PGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER-VHKGSIKETH 19086
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
+ + + Y FRV +N G + +T + V +P L G L + AG+T
Sbjct: 19087 YMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVV-VKEDLQKPVLDLKLSGVLTVKAGDT 19145
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
L V+GKP P V W K+ + + R+ ++ D G+Y A
Sbjct: 19146 IRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTA 19205
Query: 3127 TNTHGKASTYARLAVV 3142
TNT G YA + V+
Sbjct: 19206 TNTAGSFVAYATVNVL 19221
Score = 70.1 bits (164), Expect = 1e-10
Identities = 70/315 (22%), Positives = 126/315 (40%), Gaps = 37/315 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PVFS+F ++ + V L C + + V WY++ L + KY+ + ++ +
Sbjct: 6444 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHI 6503
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
LN SD EY C +NE G+ + +K+ PP F + +A L
Sbjct: 6504 LNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE-------PPRFVSKLNSLTVVAGEPAEL 6556
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ I G + W K+ +++ + + V L P ++G Y C+ +N
Sbjct: 6557 QASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND- 6615
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
G E ++ ++ E I +E P V G T L+
Sbjct: 6616 -----------GGMEENMA-TLMVLEPAVI----VEKAGP--------MTVTVGETCTLE 6651
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
++ G P VEW ++G+ +T ++ F + + +L + V ++G YT +
Sbjct: 6652 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK-ISSLRILSVERQDAGTYT---FQVQN 6707
Query: 2893 NVDMNAAITVVQPSD 2907
NV ++ VV SD
Sbjct: 6708 NVGKSSCTAVVDVSD 6722
Score = 70.1 bits (164), Expect = 1e-10
Identities = 63/209 (30%), Positives = 85/209 (40%), Gaps = 12/209 (5%)
Query: 2941 PKP-KAV-PERIPGEPCV---VDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGA 2995
PKP KA+ P PG P VD VSL W K D +P+ Y VE EG
Sbjct: 18325 PKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE---YQEEGTQ 18381
Query: 2996 RWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS-SIGVGLAGDRPEF-V 3053
W++ L+QG+ Y FRV N G G T L E V
Sbjct: 18382 DWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDV 18441
Query: 3054 DILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
++ G L + AG T ++G PVP W +G E++ + T + + F LTIK+
Sbjct: 18442 KLIEG-LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKN 18499
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y +N G + L V+
Sbjct: 18500 CLRRDTGEYQITVSNAAGSKTVAVHLTVL 18528
Score = 69.7 bits (163), Expect = 2e-10
Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 12/197 (6%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ +G+ A + G+P P + W K ++ + +G + L + + +D
Sbjct: 3250 VQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3308
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+CEA N +G A+T A L+V E + ++ V YPP L+D
Sbjct: 3309 YTCEAKNDYGVATTSASLSV-------EVPEVVSPDQEMPV---YPPAIITPLQDTVTSE 3358
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P R C+V G+ KVSWY +++ + Q E + LEIA +D G Y
Sbjct: 3359 GQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3417
Query: 3242 ARNNSGAVSCHCGLVVD 3258
A N G VS L ++
Sbjct: 3418 ASNAVGQVSSTANLSLE 3434
Score = 69.7 bits (163), Expect = 2e-10
Identities = 50/200 (25%), Positives = 89/200 (44%), Gaps = 10/200 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P + V D G +++AW + +P++ Y VE +G E +W+ + P+
Sbjct: 15211 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTE---KWMRVNSRPIK 15267
Query: 3007 SFDAFNLKQG----EEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI 3062
F +++G +EY RV N G E S+ S ++ V D +D+ + +
Sbjct: 15268 DL-KFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV-VAKDPDCKPTIDLETHDIIV 15325
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+ GE ++ + PVP V W K+G EV + + R+T + + L + D G Y
Sbjct: 15326 IEGEKLSIPVPFRAVPVPTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIY 15384
Query: 3123 SCEATNTHGKASTYARLAVV 3142
+ N G A+ + V+
Sbjct: 15385 TITLENKLGSATASINVKVI 15404
Score = 69.7 bits (163), Expect = 2e-10
Identities = 61/210 (29%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP P P PG+P V + VSL W K A + Y VE + +G RW++
Sbjct: 26604 EPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERREL-PDG--RWLK 26660
Query: 3000 LGITPLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE----FV 3053
T + F+ L + + Y FRV RN S+ S S G + D E +
Sbjct: 26661 CNYTNIQETYFEVTELTEDQRYEFRVFARNAAD--SVSEPSESTGPIIVKDDVEPPRVMM 26718
Query: 3054 DI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
D+ + + AGE + + G+P+P + W K+G E+EE A R LT+K
Sbjct: 26719 DVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA-RTEIISTDNHTLLTVK 26777
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVV 3142
D D G+Y N G S V+
Sbjct: 26778 DCIRRDTGQYVLTLKNVAGTRSVAVNCKVL 26807
Score = 69.3 bits (162), Expect = 2e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 11/169 (6%)
Query: 2609 SRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTV 2668
+RV+L V ++ T+ W+++ L + D +LE+ A +DS Y C +
Sbjct: 5710 TRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQL 5769
Query: 2669 ENENGAISTSANL--KVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
N+ G ++ A L K P F P P R+ + T EC+I G P +++
Sbjct: 5770 SNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQST--------TFECQITGTPKIRVS 5821
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
W+ D +I + ++ ++ DG+ I E+SGTY C+A N T
Sbjct: 5822 WYLDGNEITAIQKHGISFI-DGLATFQISGARVENSGTYVCEARNDAGT 5869
Score = 68.9 bits (161), Expect = 3e-10
Identities = 60/221 (27%), Positives = 87/221 (39%), Gaps = 28/221 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ GE+ L C + G P P V W + +++E + +G L I++ +D GR
Sbjct: 954 VIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI-ARLMIREAFAEDSGR 1012
Query: 3122 YSCEATNTHGKASTYARLAV------------------------VTDRTVWEADAKLKRE 3157
++C A N G ST LAV V R V D L E
Sbjct: 1013 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1072
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
++ E P T + + V+ V CQV G+P P V W K G + R
Sbjct: 1073 QAGPGEPAAPYFITKPVVQKLVEGG-SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVS 1131
Query: 3218 QDEQFH--TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++Q L I+ T DD G Y + RN G S L+
Sbjct: 1132 YNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1172
Score = 68.9 bits (161), Expect = 3e-10
Identities = 54/191 (28%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 2945 AVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP 3004
A P PG+ + D SL W K + + VL Y VE G E +W + +
Sbjct: 25137 AEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE---KWSIVAESK 25193
Query: 3005 LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKIL 3063
+ + L G+EY FRV N G + + +P LP I
Sbjct: 25194 VCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLK--LPFNTYSIQ 25251
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AGE + V G+P P + W+K+G +++ R+ + L IK+ N DD G+Y+
Sbjct: 25252 AGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT-RVNVEETATSTVLHIKEGNKDDFGKYT 25310
Query: 3124 CEATNTHGKAS 3134
ATN+ G A+
Sbjct: 25311 VTATNSAGTAT 25321
Score = 68.1 bits (159), Expect = 5e-10
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 7/178 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F ++G+ V L C + + V+WY++ L + KY+ + L ++ +
Sbjct: 8326 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHI 8385
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
LN +D EY C N+ G+ + ++ A PP F + + D + E+ L
Sbjct: 8386 LNVDAADIGEYQCKATNDVGSDTCVGSI-------ALKAPPRFVKKLSDISTVVGKEVQL 8438
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ I G + WFKD +I + ++ + L P ++G YTC+ +N
Sbjct: 8439 QTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKN 8496
Score = 68.1 bits (159), Expect = 5e-10
Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 13/191 (6%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N ++L W K + + Y VE + +G RW++ T + F
Sbjct: 24451 PGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDL-PDG--RWMKASFTNVIETQF 24507
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI-----LPGQLKIL 3063
L + + Y FRV +N G S+ S S G A D E I + +
Sbjct: 24508 TVSGLTEDQRYEFRVIAKNAAG--AISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 24565
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AGET L V GKP+P + W++ E+EE A R + F L +KD D G+Y
Sbjct: 24566 AGETFRLEADVHGKPLPTIEWLRGDKEIEESA-RCEIKNTDFKALLIVKDAIRIDGGQYI 24624
Query: 3124 CEATNTHGKAS 3134
A+N G S
Sbjct: 24625 LRASNVAGSKS 24635
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/175 (29%), Positives = 80/175 (45%), Gaps = 26/175 (14%)
Query: 3267 PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIEL 3326
P GL+ + + EG+ + + + YPS VTWYR+ ++ S +T + G L
Sbjct: 943 PTLVSGLKNVTVI-EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 1000
Query: 3327 ALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ-------------TSEPRIPPV- 3372
+ D+G +TC+A NE G STS + V +++ T E R
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 3373 -VISPDVPYSKE---------PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ D ++E P FI KP + EG +V+ C+V G+PKP VYW
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115
Score = 67.7 bits (158), Expect = 7e-10
Identities = 59/210 (28%), Positives = 86/210 (40%), Gaps = 11/210 (5%)
Query: 2941 PKPKAVPERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW 2997
P+P E+ P P VVD + LAW K D + + Y +E + +G W
Sbjct: 29464 PEPIVATEQ-PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE---MRQKGSDFW 29519
Query: 2998 VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP--EFVDI 3055
VE G T +F L + EY FRV +N G+ E + SS+ + P + I
Sbjct: 29520 VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGI 29579
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
+ AG + + G+P P V W + +E R++ LT+KD
Sbjct: 29580 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-KETDRVSITTTKDRTTLTVKDSM 29638
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDR 3145
D GRY NT G T++ VV R
Sbjct: 29639 RGDSGRYFLTLENTAG-VKTFSVTVVVIGR 29667
Score = 66.9 bits (156), Expect = 1e-09
Identities = 59/215 (27%), Positives = 96/215 (44%), Gaps = 12/215 (5%)
Query: 2931 INISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIG 2990
I + +T K VP+ PG+ V D N VSL+W K + + ++ Y VE +
Sbjct: 24042 IGLPAQTADPIKVAEVPQP-PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVE---MQ 24097
Query: 2991 AEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP 3050
A+ +W E NL QGEEY FRV N G S S ++ + +A D
Sbjct: 24098 AKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEK--GRSDPRSLAVPI-VAKDLV 24154
Query: 3051 EFVDILP--GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
D+ P + G+ + + G+P P + W K+G +++ R+ +
Sbjct: 24155 IEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTT-RINVTDSLDLTT 24213
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
L+IK+ + DD G+Y N G+ + A + +VT
Sbjct: 24214 LSIKETHKDDGGQYGITVANVVGQKT--ASIEIVT 24246
Score = 66.5 bits (155), Expect = 2e-09
Identities = 51/210 (24%), Positives = 83/210 (39%), Gaps = 10/210 (4%)
Query: 2571 KAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN 2630
K ++A S + + + + PVF LT T EG V+L+C V S + W +
Sbjct: 9250 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKA 9309
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
G + + G LE+ + +DS +Y C N G+ +T + + + +
Sbjct: 9310 GREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVA 9369
Query: 2691 PIPP-------TFTRSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDD-KQIPSDGRYQ 2741
P F S + + E ++ G P+P + W K +Q+ GR
Sbjct: 9370 PATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVF 9429
Query: 2742 AFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
D +L I + T DSG Y C A N
Sbjct: 9430 IHQKGD-EAKLEIRDTTKTDSGLYRCVAFN 9458
Score = 66.5 bits (155), Expect = 2e-09
Identities = 59/201 (29%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEG--GARW 2997
EP P PG+P ++ + V+L W K P+ T +K+ S+++ RW
Sbjct: 22276 EPMLALDPIDPPGKPVPLNITRHTVTLKWAK--PEYTG---GFKITSYIVEKRDLPNGRW 22330
Query: 2998 VELGITPL--NSFDAFNLKQGEEYHFRVTPRNRYGW-GESSQTSSSIGVGLAGDRPEF-V 3053
++ + + N F L + Y FRV +N G S+ S +I + P+ V
Sbjct: 22331 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV 22390
Query: 3054 DILPGQLKIL-AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
D+ IL AGE L V G+P P + W K+G E+E A ++ + F L K
Sbjct: 22391 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTA-KLEIKIADFSTNLVNK 22449
Query: 3113 DINIDDEGRYSCEATNTHGKA 3133
D D G Y+ ATN G A
Sbjct: 22450 DSTRRDSGAYTLTATNPGGFA 22470
Score = 66.5 bits (155), Expect = 2e-09
Identities = 57/199 (28%), Positives = 81/199 (40%), Gaps = 7/199 (3%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V D + VSLAW K APV Y VE A+
Sbjct: 25929 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGK 25988
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKIL-A 3064
F LK+ EY+FR+ N G GE + S+ + PE +D ++ +L A
Sbjct: 25989 QFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRA 26048
Query: 3065 GETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
T L ++KG+P P V W K G + +TS F L I ++ D GRY+
Sbjct: 26049 SATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFT----MLVIDNVTRFDSGRYN 26104
Query: 3124 CEATNTHGKASTYARLAVV 3142
N G + + + V+
Sbjct: 26105 LTLENNSGSKTAFVNVRVL 26123
Score = 66.1 bits (154), Expect = 2e-09
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G PT V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 66.1 bits (154), Expect = 2e-09
Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 15/175 (8%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P + L D T EG +TC S + W+RNG +L + +++ ++ + L
Sbjct: 9671 EPAWERHLQDVTLKEGQTCTMTCQ-FSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLT 9729
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + D +Y+C E+ + TSA L++ EA PI FT+ I++
Sbjct: 9730 IADVRAEDQGQYTCKYED----LETSAELRI----EAEPI--QFTKRIQNIVVSEHQSAT 9779
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYT 2766
EC + +TW+K ++ +Y + DG C + I N TP+D G Y+
Sbjct: 9780 FECEVSFDD-AIVTWYKGPTELTESQKYN--FRNDGRCHYMTIHNVTPDDEGVYS 9831
Score = 65.7 bits (153), Expect = 3e-09
Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 10/209 (4%)
Query: 2940 EPKPKAVPERIPGEPCVV---DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR 2996
EP + P +P P V D N + L W + + Y VE G++ +
Sbjct: 14504 EPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD---K 14560
Query: 2997 WVELGITPLNS-FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE-FVD 3054
WV G + + L++G+ Y +RV NR G + S+ + I + PE F+D
Sbjct: 14561 WVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLD 14620
Query: 3055 I-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
+ L L + AG L +V GKP P + W K ++++ R+T + +TI D
Sbjct: 14621 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDK-RITIENVPKKSTVTIVD 14679
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y EA N G+A+ + V+
Sbjct: 14680 SKRSDTGTYIIEAVNVCGRATAVVEVNVL 14708
Score = 65.3 bits (152), Expect = 4e-09
Identities = 107/483 (22%), Positives = 196/483 (40%), Gaps = 51/483 (10%)
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
L + V G ++ L+ I G P+ V W RE + E + ++ + G+ L + +
Sbjct: 949 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSIDFQITFQSGIARLMIREAFA 1007
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR---PEKDILIS---VGEDI 2931
+SG +TC A + G V + + V + + + + + EK + S V D
Sbjct: 1008 EDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDT 1067
Query: 2932 NISFRTQGEPKPKA--------VPERIPGEPCVVD---GGNNWVSLAWPKSD-PQTTAPV 2979
+++ G +P A V + + G V GGN + W KS P TT
Sbjct: 1068 SLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-- 1125
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
YKV + G + + +T F GE + + RN++ GE+S ++S
Sbjct: 1126 YRYKVS---YNKQTGECKLVISMT-------FADDAGE---YTIVVRNKH--GETSASAS 1170
Query: 3040 SIGVGLAGDRPEFVDILPGQLKIL--AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
+ + ++ ++ Q ++L TA + G+ PG V+ + E E+E
Sbjct: 1171 LL------EEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQAL 1224
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ + D + ++D+ + K Y R+ T + E D + K
Sbjct: 1225 IRKKM-AKD--TVVVRTYVEDQEFHISSFEERLIKEIEY-RIIKTTLEELLEEDGEEKMA 1280
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNK 3216
F +R+++ R+ V C++ G P PK++WYKDG+ + + +R +
Sbjct: 1281 VDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1340
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
+ + +L I +D G+Y A N G C L V+ AP + LEP+
Sbjct: 1341 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPA-APLGAPTYIPTLEPV 1399
Query: 3277 YKL 3279
++
Sbjct: 1400 SRI 1402
Score = 65.3 bits (152), Expect = 4e-09
Identities = 52/196 (26%), Positives = 82/196 (41%), Gaps = 10/196 (5%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE L+C V+G + W+K G E++ + R + F L ++D+ D G Y C
Sbjct: 9287 GEYVQLSCHVQGSEPIRIQWLKAGREIKP-SDRCSFSFASGTAVLELRDVAKADSGDYVC 9345
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+A+N G +T +++ T+ + A + A V+G F + RV
Sbjct: 9346 KASNVAGSDTTKSKV------TIKDKPAVAPATKKAAVDGRL--FFVSEPQSIRVVEKTT 9397
Query: 3185 VRLTCQVIGSPPPKVSWYK-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
+V G P P V W K ++ R +Q LEI T D G+Y A
Sbjct: 9398 ATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAF 9457
Query: 3244 NNSGAVSCHCGLVVDK 3259
N G + + L VD+
Sbjct: 9458 NEHGEIESNVNLQVDE 9473
Score = 64.5 bits (150), Expect = 6e-09
Identities = 31/95 (32%), Positives = 47/95 (49%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + L + T +EG V L C + PTVTWYR +++ + ++ G+ L +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
A DS ++C+ NE G +STS L V S E
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 1037
Score = 63.7 bits (148), Expect = 1e-08
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 11/188 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
P +P +VD G +++AW K AP+ Y VE W + I L +
Sbjct: 27014 PSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVE---YKKSDDTDW-KTSIQSLRGTEY 27069
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAGE 3066
L G EY FRV N+ G + S +S + P F +D + L + AG
Sbjct: 27070 TISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGA 27129
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
+ +T +G+PVP V+W K ++ A T+ LTI++ N +D G+Y+
Sbjct: 27130 SFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR---TSLTIENANRNDSGKYTLTI 27186
Query: 3127 TNTHGKAS 3134
N AS
Sbjct: 27187 QNVLSAAS 27194
Score = 62.5 bits (145), Expect = 3e-08
Identities = 53/192 (27%), Positives = 78/192 (40%), Gaps = 11/192 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V D + VSL+W K +P++ Y VE + WV + P N
Sbjct: 20515 PPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVE---VKRADSDNWVRCNL-PQN 20570
Query: 3007 ----SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG--LAGDRPEFVDILPGQL 3060
F+ L + +Y FRV N+ G+ + S L E L L
Sbjct: 20571 LQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTL 20630
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+ AG T L VKG+P P + W K + + G + + FD L +++N D G
Sbjct: 20631 ILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKSTDFDTFLRCENVNKYDAG 20689
Query: 3121 RYSCEATNTHGK 3132
+Y N+ GK
Sbjct: 20690 KYILTLENSCGK 20701
Score = 62.1 bits (144), Expect = 3e-08
Identities = 32/84 (38%), Positives = 42/84 (50%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E+ + F I++ L + C++ G PLPKI W+KD K+I RYQ +L D
Sbjct: 1285 ESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1344
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAEN 2771
G L I PED G YT A N
Sbjct: 1345 GRASLRIPVVLPEDEGIYTAFASN 1368
Score = 62.1 bits (144), Expect = 3e-08
Identities = 64/238 (26%), Positives = 103/238 (43%), Gaps = 31/238 (13%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG-GVYEVTAR 3243
V LT + + +V+WY + + V D++ QD+ +TL I N +D G Y A
Sbjct: 4306 VHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 4363
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+SG + L V K RA AP +EPL ++ G + + +++ P+V W++
Sbjct: 4364 NDSGKTATSAKLTVVK--RA--APVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFK 4418
Query: 3304 DGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
G + S + +I + +E+ V D G YTC ASNE G S + + V T+
Sbjct: 4419 AGREIYESDKCSIRSSKYISSLEILRTQVV--DCGEYTCKASNEYGSVSCTATLTV--TE 4474
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ P F+ +P+S G C V G P + W +D
Sbjct: 4475 ------------------AYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKD 4514
Score = 62.1 bits (144), Expect = 3e-08
Identities = 58/205 (28%), Positives = 83/205 (40%), Gaps = 12/205 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P + D L W K +P+L Y VE G A+W + L
Sbjct: 18730 PPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQ---KPGTAQWNRINKDELI 18786
Query: 3007 SFDAFN---LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LK 3061
AF L +G EY FR+ N G GE + + S+ PE +D+ +
Sbjct: 18787 RQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVIT 18846
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+ G+T + VKG+P P + W K G V E+ + + L IK+ D G
Sbjct: 18847 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE--LQIKEAVRADHG 18904
Query: 3121 RYSCEATNTHGKASTYARLAVVTDR 3145
+Y A N+ G A A + V DR
Sbjct: 18905 KYIISAKNSSGHAQGSA-IVNVLDR 18928
Score = 61.7 bits (143), Expect = 5e-08
Identities = 53/189 (28%), Positives = 81/189 (42%), Gaps = 8/189 (4%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQ 3015
V + N +LAW A + Y + S+ + RW E + S LK+
Sbjct: 19734 VTEMTKNSATLAWLPPLRDGGAKIDGY-ITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 19792
Query: 3016 GEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDILPGQLKILAGETANLTCS 3073
G++Y FRV RN G S + GV A ++ P + ++P Q+ I AG+ +
Sbjct: 19793 GKKYKFRVAARNAVG---VSLPREAEGVYEAKEQLLPPKI-LMPEQITIKAGKKLRIEAH 19848
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
V GKP P W K EV + + + L IKD+ D G YS A N+ G
Sbjct: 19849 VYGKPHPTCKWKKGEDEVVTSSHLAVHKADS-SSILIIKDVTRKDSGYYSLTAENSSGTD 19907
Query: 3134 STYARLAVV 3142
+ ++ V+
Sbjct: 19908 TQKIKVVVM 19916
Score = 61.3 bits (142), Expect = 6e-08
Identities = 75/354 (21%), Positives = 141/354 (39%), Gaps = 23/354 (6%)
Query: 2571 KAFSEARSVISEKRTLSRNSTR--KPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTV 2625
K F E+R V+ +L+ +P F+T + VEG V C V + P V
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113
Query: 2626 TWYRNGVLLDNKLKYRKKL--VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
W ++GV L +Y+ G L + D+ EY+ V N++G S SA+L
Sbjct: 1114 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1173
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA 2742
+E +S ++ + + V E ++ G+ P + + +K+ + QA
Sbjct: 1174 EADYE------LLMKSQQEMLYQTQVTAFVQEPKV-GETAPGFVYSEYEKEYEKE---QA 1223
Query: 2743 FYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
+ ED + E + +I + + T E + + EK
Sbjct: 1224 LIRKKMAKDTVVVRTYVEDQEFHISSFEERL-IKEIEYRIIKTTLEELLEED--GEEKMA 1280
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARV 2861
+ E+ F + +Y++ G + ++ G P ++ W ++G+ + R
Sbjct: 1281 VDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1340
Query: 2862 FVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVI 2915
F++ G +L + V + G+YT A + GN + + V+P+ G P I
Sbjct: 1341 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL-YVEPAAPLGAPTYI 1393
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/204 (26%), Positives = 83/204 (40%), Gaps = 8/204 (3%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELG 3001
K A P P P V D SLAW K + Y VE +G E +
Sbjct: 21594 KDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGT 21653
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQ 3059
+ F +L+ E+Y+FR++ N G GE + + + P+F +D L
Sbjct: 21654 ALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA-VIPDVEIVEREMAPDFELDAELRRT 21712
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDD 3118
L + AG + + +KG+P P V W K+ ++ A T F L I + N D
Sbjct: 21713 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFT----LLIIPECNRYD 21768
Query: 3119 EGRYSCEATNTHGKASTYARLAVV 3142
G++ N GK S + + V+
Sbjct: 21769 TGKFVMTIENPAGKKSGFVNVRVL 21792
Score = 60.9 bits (141), Expect = 8e-08
Identities = 56/262 (21%), Positives = 101/262 (38%), Gaps = 27/262 (10%)
Query: 3159 SAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ 3218
SA V PP F ++ + GS P V+W KD +E+ D
Sbjct: 5404 SARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF 5463
Query: 3219 DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
+ +L ++ + G Y A+N++G C L V + A + E
Sbjct: 5464 ENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP--ATITEEAVS-----ID 5516
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ +GD + + W++DG L + +++ I L + + +D+G
Sbjct: 5517 VTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSI-LKIISTEKKDSGE 5575
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
YT N+VGR+S ++ V+ +I P P F +K + ++ +G
Sbjct: 5576 YTFEVQNDVGRSSCKARINVLD------------LIIP-------PSFTKKLKKMDSIKG 5616
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
+ +EC V G + W +D
Sbjct: 5617 SFIDLECIVAGSHPISIQWFKD 5638
Score = 60.9 bits (141), Expect = 8e-08
Identities = 54/207 (26%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2947 PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESW--LIGAEGGARWVELG 3001
P PG P VVD + ++L W K AP++ Y VE + A W
Sbjct: 19420 PIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCN 19479
Query: 3002 ITPL---NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPG 3058
F +L + +EY FRV +N+ G G ++ +I + PE +D+
Sbjct: 19480 AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPE-IDLDAS 19538
Query: 3059 QLKIL---AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
K++ AG L V+G+P P V W K G + G++ L I +
Sbjct: 19539 MRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQV--DLVDTMAFLVIPNST 19596
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVV 3142
DD G+YS N G+ + + + V+
Sbjct: 19597 RDDSGKYSLTLVNPAGEKAVFVNVRVL 19623
Score = 60.9 bits (141), Expect = 8e-08
Identities = 54/196 (27%), Positives = 85/196 (43%), Gaps = 9/196 (4%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGA-EGGARWVELGITPLNSFD 3009
P P V+D + V L+W K + Y VE + E GI N +
Sbjct: 23768 PNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN-IE 23826
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAGET 3067
L + EY+FR+ N+ G GE + I V + P+ +D+ L + I AG +
Sbjct: 23827 VEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGS 23886
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
L +KG+P P V W K E+ + A +TS F L + ++N D G+Y+
Sbjct: 23887 LRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTS----LVLDNVNRYDSGKYTLTL 23942
Query: 3127 TNTHGKASTYARLAVV 3142
N+ G S + + V+
Sbjct: 23943 ENSSGTKSAFVTVRVL 23958
Score = 60.5 bits (140), Expect = 1e-07
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 15/173 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D T G C +S D V WY G L+ K + + TL + +
Sbjct: 13129 LKDVTVTAGETATFDCE-LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 13187
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ E T ++ T ANL F P P FT+ + D VLEC +
Sbjct: 13188 DAGEVQLTAKD----FKTHANL-----FVKEP-PVEFTKPLEDQTVEEGATAVLECEVSR 13237
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAEN 2771
+ K+ WFK+ +I +Y+ +ADG V +L I + TPED TYTC A++
Sbjct: 13238 ENA-KVKWFKNGTEILKSKKYEI--VADGRVRKLVIHDCTPEDIKTYTCDAKD 13287
Score = 60.5 bits (140), Expect = 1e-07
Identities = 51/187 (27%), Positives = 83/187 (44%), Gaps = 19/187 (10%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVL 2654
F+ L D+T EG+ L C V S + V W++NG + KY + + DG + L +
Sbjct: 13214 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKY-EIVADGRVRKLVIH 13271
Query: 2655 NAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-L 2713
+ P D Y+C ++ TS NL V P F R + D + E E+
Sbjct: 13272 DCTPEDIKTYTCDAKD----FKTSCNLNVVPPH------VEFLRPLTD-LQVREKEMARF 13320
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENS 2772
EC + + K+ WFKD +I +Y ++ G R L I+ +D Y+C+ +
Sbjct: 13321 ECEL-SRENAKVKWFKDGAEIKKGKKYD--IISKGAVRILVINKCLLDDEAEYSCEVRTA 13377
Query: 2773 VWTDQIT 2779
+ +T
Sbjct: 13378 RTSGMLT 13384
Score = 60.5 bits (140), Expect = 1e-07
Identities = 51/175 (29%), Positives = 81/175 (46%), Gaps = 17/175 (9%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN-AVP 2658
LTD E + C +S + V W+++G + KY + G + + V+N +
Sbjct: 13307 LTDLQVREKEMARFECE-LSRENAKVKWFKDGAEIKKGKKY-DIISKGAVRILVINKCLL 13364
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D AEYSC V TS L V EA FT+++ + + + L C +
Sbjct: 13365 DDEAEYSCEVRTAR----TSGMLTVLEE-EA-----VFTKNLANIEVSETDTIKLVCEV- 13413
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENS 2772
+P ++ W+K D++I GRY+ L +G R L I N ED+G Y C+ +S
Sbjct: 13414 SKPGAEVIWYKGDEEIIETGRYE--ILTEGRKRILVIQNAHLEDAGNYNCRLPSS 13466
Score = 60.5 bits (140), Expect = 1e-07
Identities = 54/193 (27%), Positives = 81/193 (41%), Gaps = 9/193 (4%)
Query: 2947 PERIPGEPCVV---DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P PG P VV D VSL W K ++ Y +E G V
Sbjct: 29177 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADL-GDWHKVNAEAC 29235
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKI 3062
+ +L+ GEEY FRV+ N G G+S + + +I PE +D Q +
Sbjct: 29236 VKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHV 29295
Query: 3063 L-AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AG + L + +G+P P VW K + A T+ + F LT+++ N +D G+
Sbjct: 29296 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT--DSFS-TLTVENCNRNDAGK 29352
Query: 3122 YSCEATNTHGKAS 3134
Y+ N G S
Sbjct: 29353 YTLTVENNSGSKS 29365
Score = 60.1 bits (139), Expect = 1e-07
Identities = 76/346 (21%), Positives = 130/346 (37%), Gaps = 35/346 (10%)
Query: 2568 HRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW 2627
++ + +E S I R R P F + +++ G ++ S TVTW
Sbjct: 5390 YQCRVTNEVGSSICSARVTLREP---PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTW 5446
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
++ + R + + +L + +Y C +N+ G SA L V
Sbjct: 5447 LKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE-- 5504
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
P T T + L+ + G WFKD +++ +Y+ + D
Sbjct: 5505 -----PATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYK-ISVTD 5558
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQS 2807
V L I + +DSG YT + +N V GR S K RI
Sbjct: 5559 TVSILKIISTEKKDSGEYTFEVQNDV------------GRSSC---------KARINVLD 5597
Query: 2808 LESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQG 2866
L P F L +G I L+ + G P ++W ++ + ++ + F +
Sbjct: 5598 L-IIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNT 5656
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKP 2912
+ L +S + T+SG YTC A + G+ + +TV +P KP
Sbjct: 5657 AF-LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKP 5701
Score = 60.1 bits (139), Expect = 1e-07
Identities = 62/263 (23%), Positives = 104/263 (39%), Gaps = 17/263 (6%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG P V+D + +S+AW K + + Y VE L + S+
Sbjct: 22686 PGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTI 22745
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDI---LPGQLKILAG 3065
L + +EY R+ N G GE + G A DR P +++ L + I A
Sbjct: 22746 TGLTENQEYKIRIYAMNSEGLGEPALVP---GTPKAEDRMLPPEIELDADLRKVVTIRAC 22802
Query: 3066 ETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
T L +KG+P P V W + +G +++ + TS + L + ++N D G+Y
Sbjct: 22803 CTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYT----LLIVGNVNRFDSGKYIL 22858
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFT---MRLRDRRVQA 3181
N+ G S + + V+ D D K+K V + P ++++ V+
Sbjct: 22859 TVENSSGSKSAFVNVRVL-DTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEK 22917
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKD 3204
R + + K SW D
Sbjct: 22918 RESTRKAYSTVATNCHKTSWKVD 22940
Score = 59.3 bits (137), Expect = 2e-07
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 18/149 (12%)
Query: 3273 LEPL-YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P+ +K EG R V P W+ DG ++ + + DG L +
Sbjct: 1461 LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPA 1520
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
T D+G +T A N GR+S + VI T + E ++ +PMF+ K +
Sbjct: 1521 TPSDSGEWTVVAQNRAGRSS----ISVILTVEAVEHQV-------------KPMFVEKLK 1563
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ +EG + ++ G+P PD+ WL++
Sbjct: 1564 NVNIKEGSQLEMKVRATGNPNPDIVWLKN 1592
Score = 59.3 bits (137), Expect = 2e-07
Identities = 50/180 (27%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+ T L D + EG V LT S+ ++ + V WY L+ + K++ TL +
Sbjct: 4289 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4346
Query: 2654 LNAVPSD-SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENEL 2711
D EY C N++G +TSA L V A+P+ + HLA+
Sbjct: 4347 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK--RAAPVIKRKIEPLEVALGHLAK--- 4401
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C I+ P + WFK ++I + + + + L I D G YTCKA N
Sbjct: 4402 -FTCEIQSAPNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKASN 4459
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/277 (24%), Positives = 115/277 (41%), Gaps = 32/277 (11%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRYS 3123
G A+ V GKP P W KNG ++E + R+ + + C L I+D+ +D
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIER-SDRIYWYWPEDNVCELVIRDVTAEDSASIM 2150
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
+A N G+ S++A L V AK + E++ + +++ AT+
Sbjct: 2151 VKAINIAGETSSHAFLLV---------QAKQLITFTQELQD-------VVAKEKDTMATF 2194
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C+ P KV WYKDG EV + + D + H L I + D Y
Sbjct: 2195 E----CET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+ V L+V+ + EF L+ + ++ E + +V ++ WY
Sbjct: 2250 EDEN-VKTTAKLIVEGAV-----VEFVKELQDI-EVPESYSGELECIVSP-ENIEGKWYH 2301
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
+ V L+ + + +T R G+ L + VT D G Y+
Sbjct: 2302 NDVELKSNGKYTIT-SRRGRQNLTVKDVTKEDQGEYS 2337
Score = 58.8 bits (136), Expect = 3e-07
Identities = 55/208 (26%), Positives = 92/208 (44%), Gaps = 8/208 (3%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP P PG+P V++ N V+L W + + Y VE + ++ +
Sbjct: 21193 EPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANH 21252
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW-GESSQTSSSIGVGLAGDRPEFV--DIL 3056
+ + P +F +L +G +Y FR+ +N G S+++ +I + P V +
Sbjct: 21253 VNV-PECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTI 21311
Query: 3057 PGQLKILAGETANLTC-SVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
L I AG+T L S+ GKP+P W K G ++ + ++TS LTIK
Sbjct: 21312 KDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITS--TPTSSMLTIKYA 21369
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y+ ATN G + ++ V+
Sbjct: 21370 TRKDAGEYTITATNPFGTKVEHVKVTVL 21397
Score = 58.4 bits (135), Expect = 4e-07
Identities = 54/216 (25%), Positives = 92/216 (42%), Gaps = 16/216 (7%)
Query: 2939 GEPKPKAV------PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLI 2989
GEP P V P PG P +VD N ++LAW K + +L Y VE
Sbjct: 24829 GEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA 24888
Query: 2990 GAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR 3049
E + F+ L + +EY RV N+ G GE++ ++ +
Sbjct: 24889 DEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEA 24948
Query: 3050 PEFVDI---LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
PE +D+ L + + AG +A + KG+P P + W + E ++ ++ N
Sbjct: 24949 PE-LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKV-QIEKGVNYTQ 25006
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L+I + + +D G+Y + N+ G S + + V+
Sbjct: 25007 --LSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVL 25040
Score = 58.0 bits (134), Expect = 6e-07
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 58.0 bits (134), Expect = 6e-07
Identities = 51/206 (24%), Positives = 82/206 (39%), Gaps = 6/206 (2%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP + P PG +VD N ++ W K + + + Y VE + +G +W
Sbjct: 26215 EPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVE---MQTKGSEKWST 26271
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
L GEEY FRV N G + Q + +P V++
Sbjct: 26272 CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS-VELPFHT 26330
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ A E + KG+P V W K+G ++E R+ + L+IK+ + +D
Sbjct: 26331 FNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETT-RVNVSSSKTVTSLSIKEASKEDV 26389
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDR 3145
G Y +N+ G + T +V DR
Sbjct: 26390 GTYELCVSNSAG-SITVPITIIVLDR 26414
Score = 58.0 bits (134), Expect = 6e-07
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 7/184 (3%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRV 3023
VSL W K + + ++ Y VE+ +G WV+ + L++ EY FRV
Sbjct: 27318 VSLTWLKPEHDGGSRIVHYVVEAL---EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRV 27374
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LKILAGETANLTCSVKGKPVPG 3081
N+ G + + + + + PE + P + + AG + + GKP+P
Sbjct: 27375 FAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPK 27434
Query: 3082 VVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
V ++G ++ R ++ + + +K+ D GRY A N+ G + + V
Sbjct: 27435 VTLSRDGVPLKATM-RFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINI-V 27492
Query: 3142 VTDR 3145
V DR
Sbjct: 27493 VLDR 27496
Score = 57.2 bits (132), Expect = 1e-06
Identities = 90/397 (22%), Positives = 152/397 (38%), Gaps = 56/397 (14%)
Query: 3076 GKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAS 3134
G P V W+ +G +E RM ++F G+ C L D G +C ATN +G
Sbjct: 1730 GDPTMVVEWLHDGKPLEAANRLRMINEF-GY-CSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 3135 TYARLAVVTDRTVWEA----DAKLKRERSAEVEG----------------DYPPQFTMRL 3174
T A L V ++++ E + + +R E+E P +
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1847
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
RV R C+V G P PKV+WY +G +++ +R + + + H L+I D
Sbjct: 1848 EPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIHYLDIVDCKSYD 1906
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD--KGIRAYV--APEFCCGLEPLYKLHEGDELRISAV 3290
G +VTA N G + L + + R+ + APE P + +HE +L+ V
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPE----PRPEFHVHEPGKLQFE-V 1961
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV-GR 3349
+ V T ++ V+L+ + R + EL + G Y + E+ R
Sbjct: 1962 QKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSR 2021
Query: 3350 ASTSGKVEVIG-------------TDQ-----TSEPRIPPVVISPD----VPYSKEPMFI 3387
E++ T++ E +I PD P + P
Sbjct: 2022 KKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF 2081
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+ +S +G VVG P P+ W ++ +K+
Sbjct: 2082 ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2118
Score = 57.2 bits (132), Expect = 1e-06
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 3/201 (1%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELG 3001
+P VPER P + V + N V+L W + ++ Y +ES LIG E +
Sbjct: 17639 EPITVPER-PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 17697
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLK 3061
+ + LK+G+ Y +RV+ N G G+ S + I P +L
Sbjct: 17698 LLS-RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLT 17756
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GE LT GKP P V W K+ +V E+ R + L D G+
Sbjct: 17757 IRVGEAFALTGRYSGKPKPKVSWFKDEADVLED-DRTHIKTTPATLALEKIKAKRSDSGK 17815
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y N+ G + ++ VV
Sbjct: 17816 YCVVVENSTGSRKGFCQVNVV 17836
Score = 56.8 bits (131), Expect = 1e-06
Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD +S V P + W+ +GV L PS D D L + D G YTC
Sbjct: 3517 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTC 3575
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM---FIRKPRSSEAREG 3398
ASN+ G+ S +++ + + ++ + P F+++ + +G
Sbjct: 3576 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3635
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
I E VVG+P P V W ++
Sbjct: 3636 LPAIFEYTVVGEPAPTVTWFKE 3657
Score = 56.8 bits (131), Expect = 1e-06
Identities = 52/192 (27%), Positives = 78/192 (40%), Gaps = 8/192 (4%)
Query: 2951 PGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS 3007
PG P + D + ++L W K + V Y VE E G
Sbjct: 28094 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTE 28153
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAG 3065
+ NLK G Y+FRV+ N G GE + + + + PE +D+ L + AG
Sbjct: 28154 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 28213
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
E + KG+P P V W K+ + +A R + + LTI + +D G+Y
Sbjct: 28214 EDVQVLIPFKGRPPPTVTWRKDEKNLGSDA-RYSIENTDSSSLLTIPQVTRNDTGKYILT 28272
Query: 3126 ATNTHG--KAST 3135
N G K+ST
Sbjct: 28273 IENGVGEPKSST 28284
Score = 56.4 bits (130), Expect = 2e-06
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 11/178 (6%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVLNAVPSDSA 2662
T V+G + L+C + D V W ++G ++ K V GL+ L + +A +D+
Sbjct: 12150 TVVKGQPLYLSCELNKERD--VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAG 12207
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+ TVEN N + S+ +KV I + IRD + + C I +
Sbjct: 12208 TYTVTVENANN-LECSSCVKV-----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDT 12260
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P I WFK +IP++ + L DG L I N PED Y + E + ++T
Sbjct: 12261 PNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLT 12318
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 8/194 (4%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDEQFHTLE 3226
P+ R++ + V +V+G P P+ WYK+G ++ R Y ++ L
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I +D V A N +G S H L+V +A F L+ + E D +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQLITFTQELQDVV-AKEKDTMA 2192
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ P V V WY+DG+ + + M DR L++ + T DA Y+C E
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHF-LSILTIDTSDAEDYSCVLV-E 2250
Query: 3347 VGRASTSGKVEVIG 3360
T+ K+ V G
Sbjct: 2251 DENVKTTAKLIVEG 2264
Score = 56.0 bits (129), Expect = 2e-06
Identities = 57/212 (26%), Positives = 88/212 (41%), Gaps = 22/212 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP-- 3004
P P P V D + +SL W +P+ Y VE + EG W +
Sbjct: 16631 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVE---MQEEGTTDWKRVNEPDKL 16687
Query: 3005 LNSFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE-FVDI-LPGQL 3060
+ + + NLK+ +Y FRV N G E S T+ I + PE F+DI L
Sbjct: 16688 ITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCL 16747
Query: 3061 KILAGETANLTCSVKGKPVPGVVW---------MKNG-HEVEEEAGRMTSQFNGFDCCLT 3110
AG + +KG+P P W MK+G H++ E+A T++ + +
Sbjct: 16748 VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS---VII 16804
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I + G+YS A N G+ + R+ V+
Sbjct: 16805 IPECKRSHTGKYSITAKNKAGQKTANCRVKVM 16836
Score = 55.6 bits (128), Expect = 3e-06
Identities = 53/207 (25%), Positives = 86/207 (41%), Gaps = 13/207 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP + P ++D + VSLAWPK + + Y +E+ +G +W
Sbjct: 21884 EPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEA---QRKGSDQWTH 21940
Query: 3000 LGITPLNSFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP 3057
IT + + NL +GEEY F+V N G + + S + V PE +D+
Sbjct: 21941 --ITTVKGLECVVRNLTEGEEYTFQVMAVNSAG-RSAPRESRPVIVKEQTMLPE-LDLRG 21996
Query: 3058 GQLKIL---AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
K++ AG+ + V G+P P V W K G ++ ++ R+ + L I +
Sbjct: 21997 IYQKLVIAKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINEC 22055
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAV 3141
D G Y A N G+ + V
Sbjct: 22056 VRSDSGPYPLTARNIVGEVGDVITIQV 22082
Score = 55.2 bits (127), Expect = 4e-06
Identities = 29/90 (32%), Positives = 43/90 (47%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P + +QA +++ VIG P P +SW KDGE + R N + L I
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 25298
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
N DD G Y VTA N++G + + ++V
Sbjct: 25299 KEGNKDDFGKYTVTATNSAGTATENLSVIV 25328
Score = 54.8 bits (126), Expect = 5e-06
Identities = 50/230 (21%), Positives = 86/230 (37%), Gaps = 5/230 (2%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P F + + + + L + G P PKI WF + + Y+ + D +
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
+ ED G YTC A N + ++ + + + + P
Sbjct: 3563 LFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3621
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLA 2871
HF L + A+G + + G P V W +E + + T VY + G T
Sbjct: 3622 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTI-IHNPNGSGTFI 3680
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPE 2920
++D +SGLY C+A + G A + V ++ +D+ P PE
Sbjct: 3681 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPE 3730
Score = 54.8 bits (126), Expect = 5e-06
Identities = 61/256 (23%), Positives = 99/256 (38%), Gaps = 25/256 (9%)
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAG 3065
NS+ L++G Y+FRVT N YG G +QT+ I V P + + ++
Sbjct: 24017 NSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSL 24076
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
K + +V M+ H E E R+ S I ++ +E +
Sbjct: 24077 SWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKS------LQAVITNLTQGEEYLFRV 24130
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G++ + + + + +E D P F+ VQ
Sbjct: 24131 VAVNEKGRSDPRSLAVPIVAKDL-------------VIEPDVKPAFS----SYSVQVGQD 24173
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+++ + G P P ++W KDG + R N TL I T+ DDGG Y +T N
Sbjct: 24174 LKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVAN 24233
Query: 3245 NSGAVSCHCGLV-VDK 3259
G + +V +DK
Sbjct: 24234 VVGQKTASIEIVTLDK 24249
Score = 54.4 bits (125), Expect = 7e-06
Identities = 54/214 (25%), Positives = 90/214 (42%), Gaps = 25/214 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDC 3107
+P FV + P K L G+TA V G+P+P W +G + V + ++ + +G
Sbjct: 1456 KPVFV-LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ- 1513
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I D G ++ A N G++S L V EA VE
Sbjct: 1514 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV-------EA-----------VEHQVK 1555
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVV---YDKRRNKYQDEQFHT 3224
P F +L++ ++ + + + G+P P + W K+ + +V Y K R + +
Sbjct: 1556 PMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE-AA 1614
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
L+I T D Y TA N +G + C + V+
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648
Score = 54.4 bits (125), Expect = 7e-06
Identities = 47/141 (33%), Positives = 65/141 (46%), Gaps = 14/141 (9%)
Query: 3230 TNLDDGGVYE--VTARNNSGAVSC---HCGLVV--DKGIRAYV--APEFCCGLEPLYKLH 3280
T L G YE + ARN G +S G+++ D+ + V PE+ GL +
Sbjct: 28843 TGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLI----IK 28898
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
G+ LRI A+V+ P VTW++DGV + R + D G L + T GVYT
Sbjct: 28899 SGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNMEITDVLGSTSLFVRDATRDHRGVYT 28957
Query: 3341 CTASNEVGRASTSGKVEVIGT 3361
A N G A KV+V T
Sbjct: 28958 VEAKNASGSAKAEIKVKVQDT 28978
Score = 53.6 bits (123), Expect = 1e-05
Identities = 56/229 (24%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+E EG P F + + + L+ VIG P PK+ W+ +G + D
Sbjct: 3496 SEKEGT-GPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 3554
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--------DKGIRAYVA----- 3266
H+L I T L+D G Y A N+ G C L + D + VA
Sbjct: 3555 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3614
Query: 3267 ------PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR 3320
P F L+P+ + +G V P+ VTW+++ +L S + +
Sbjct: 3615 LGGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 3673
Query: 3321 DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI--GTDQTSEP 3367
+G + D+G+Y C A N +G ++ + ++ V+ TD T P
Sbjct: 3674 NGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3722
Score = 53.6 bits (123), Expect = 1e-05
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 6/151 (3%)
Query: 2947 PERIPGEPCVVDGGN---NWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P++ P P V+ N +++ W + ++ Y +E G E R E +
Sbjct: 15503 PKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNE-HLV 15561
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL 3063
P+ ++ A L++G+EY FRV N G E S+ + D P+ IL L++
Sbjct: 15562 PILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV--ILRTSLEVK 15619
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
G+ L S+ G P P + W+K+ + + E
Sbjct: 15620 RGDEIALDASISGSPYPTITWIKDENVIVPE 15650
Score = 53.6 bits (123), Expect = 1e-05
Identities = 50/195 (25%), Positives = 78/195 (40%), Gaps = 6/195 (3%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT-PLNSFD 3009
P P +D N V L W + +L Y VE +G E R + P +
Sbjct: 18043 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 18102
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFV-DI-LPGQLKILAGET 3067
L+ G+ Y FRV N G + + + V + PE + D + + I G+T
Sbjct: 18103 VTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDT 18162
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L+ +KG P P V W K + +A R+ G L I++ +D G YS
Sbjct: 18163 LRLSAIIKGVPFPKVTWKKEDRDAPTKA-RIDVTPVGSK--LEIRNAAHEDGGIYSLTVE 18219
Query: 3128 NTHGKASTYARLAVV 3142
N G + ++ V+
Sbjct: 18220 NPAGSKTVSVKVLVL 18234
Score = 53.6 bits (123), Expect = 1e-05
Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 11/170 (6%)
Query: 2958 DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGE 3017
D V L+W K D + + Y VE +G W GI+ + LK+
Sbjct: 28400 DSTKTSVILSWTKPDFDGGSVITEYVVER---KGKGEQTWSHAGISKTCEIEVSQLKEQS 28456
Query: 3018 EYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI--LPG-QLKILAGETANLTCSV 3074
FRV +N G + T I V PE VD+ +PG Q+ + G +L
Sbjct: 28457 VLEFRVFAKNEKGLSDPV-TIGPITVKELIITPE-VDLSDIPGAQVTVRIGHNVHLELPY 28514
Query: 3075 KGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
KGKP P + W+K+G ++E E R + N L+IK+ + G+Y+
Sbjct: 28515 KGKPKPSISWLKDGLPLKESEFVRFSKTEN--KITLSIKNAKKEHGGKYT 28562
Score = 52.4 bits (120), Expect = 3e-05
Identities = 52/183 (28%), Positives = 80/183 (43%), Gaps = 15/183 (8%)
Query: 2965 SLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVT 3024
S+ W K + ++ Y V+ + E +W + + + A +L +G+EY FRV+
Sbjct: 20828 SIGWKKPHSDGGSRIIGYVVD--FLTEEN--KWQRVMKSLSLQYSAKDLTEGKEYTFRVS 20883
Query: 3025 PRNRYGWGESSQTSSSIGVGLAGDRPEFVDI-LPG--QLKILAGETAN--LTCSVKGKPV 3079
N G G T S I V +A D D+ L G L LA E +N L +KGKP
Sbjct: 20884 AENENGEG----TPSEITV-VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 20938
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
P V W K G + R++ + + + L + D D G+Y+ N G +
Sbjct: 20939 PSVSW-KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISI 20997
Query: 3140 AVV 3142
VV
Sbjct: 20998 KVV 21000
Score = 52.4 bits (120), Expect = 3e-05
Identities = 54/199 (27%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--FDAFNL 3013
+ D N VSL+W + + + Y VE + +G RW + T + F L
Sbjct: 27703 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDL-PDG--RWTKASFTNVTETQFIISGL 27759
Query: 3014 KQGEEYHFRVTPRNRYGWGESSQTSSSIGV--------GLAGDRP-EFVDILPGQLKILA 3064
Q +Y FRV RN G S S +G G D P E+ +++ K A
Sbjct: 27760 TQNSQYEFRVFARNAVG--SISNPSEVVGPITCIDSYGGPVIDLPLEYTEVV----KYRA 27813
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD-CCLTIKDINIDDEGRYS 3123
G + L + GKP P + W K+ E++ A + N D + IKD + + G Y
Sbjct: 27814 GTSVKLRAGISGKPAPTIEWYKDDKELQTNA--LVCVENTTDLASILIKDADRLNSGCYE 27871
Query: 3124 CEATNTHGKASTYARLAVV 3142
+ N G AS R+ ++
Sbjct: 27872 LKLRNAMGSASATIRVQIL 27890
Score = 52.0 bits (119), Expect = 4e-05
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG++L I A P V+W++DG ++ S R M D L + DAG+YT
Sbjct: 15327 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISA-HLEVPKSVRADAGIYT 15385
Query: 3341 CTASNEVGRASTSGKVEVIG 3360
T N++G A+ S V+VIG
Sbjct: 15386 ITLENKLGSATASINVKVIG 15405
Score = 51.6 bits (118), Expect = 5e-05
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK-Y 2640
+K LS + +F + +T +GS V+ DP WY+NGV ++ + Y
Sbjct: 2067 DKIELSPSMEAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2125
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSI 2700
D + L + + DSA N G S+ A L V +A + TFT+ +
Sbjct: 2126 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQL-ITFTQEL 2180
Query: 2701 RDTFHLAENEL-VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+D ++ + EC +P K+ W+KD ++ +Y+ + V L+I
Sbjct: 2181 QDVVAKEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSDRKVHFLSILTIDT 2238
Query: 2760 EDSGTYTC 2767
D+ Y+C
Sbjct: 2239 SDAEDYSC 2246
Score = 51.2 bits (117), Expect = 6e-05
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T + +KP + +EG + C V P V WY NG L+ ++R +
Sbjct: 1832 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR- 1890
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
DG+ L++++ D+ E T EN G I L++
Sbjct: 1891 YDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 50.8 bits (116), Expect = 8e-05
Identities = 53/181 (29%), Positives = 79/181 (43%), Gaps = 33/181 (18%)
Query: 3065 GETANLTCSVKGKPVPGVV--WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
G+T +TC VP V W +NG ++ + GR ++ LTI D+ +D+G+Y
Sbjct: 9686 GQTCTMTCQFS---VPNVKSEWFRNGRILKPQ-GRHKTEVEHKVHKLTIADVRAEDQGQY 9741
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+C+ Y L E A+L+ E AE P QFT R+++ V
Sbjct: 9742 TCK----------YEDL---------ETSAELRIE--AE-----PIQFTKRIQNIVVSEH 9775
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
C+V V+WYK E+ ++ N D + H + I DD GVY V A
Sbjct: 9776 QSATFECEV-SFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 9834
Query: 3243 R 3243
R
Sbjct: 9835 R 9835
Score = 50.8 bits (116), Expect = 8e-05
Identities = 78/344 (22%), Positives = 137/344 (39%), Gaps = 47/344 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AGETA C + + +P V W G ++E + ++ + G LT++D+ ++D G
Sbjct: 13134 VTAGETATFDCELSYEDIP-VEWYLKGKKLEP-SDKVVPRSEGKVHTLTLRDVKLEDAG- 13190
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
E T T+A L V + P +FT L D+ V+
Sbjct: 13191 ---EVQLTAKDFKTHANLFV----------------------KEPPVEFTKPLEDQTVEE 13225
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
L C+V KV W+K+G E++ K+ D + L I +D Y
Sbjct: 13226 GATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCD 13284
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A++ SC+ +V EF L L ++ E + R + + + V W
Sbjct: 13285 AKDFK--TSCNLNVVPPH-------VEFLRPLTDL-QVREKEMARFECEL-SRENAKVKW 13333
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++DG ++ ++ + + + L + D Y+C EV A TSG + V+
Sbjct: 13334 FKDGAEIKKGKKYDI-ISKGAVRILVINKCLLDDEAEYSC----EVRTARTSGMLTVLEE 13388
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA-REGDTVIIE 3404
+ + + +S + K + KP + +GD IIE
Sbjct: 13389 EAVFTKNLANIEVS-ETDTIKLVCEVSKPGAEVIWYKGDEEIIE 13431
Score = 50.8 bits (116), Expect = 8e-05
Identities = 27/80 (33%), Positives = 41/80 (51%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G+ V L +V PTV+W ++G LL + + L TLE+ + DS +
Sbjct: 20233 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGD 20292
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y+ T EN +G+ S + LKV
Sbjct: 20293 YTITAENSSGSKSATIKLKV 20312
Score = 50.8 bits (116), Expect = 8e-05
Identities = 75/312 (24%), Positives = 120/312 (38%), Gaps = 33/312 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P +P V + N +++W + + + Y VE + RWV TP++
Sbjct: 21498 PPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVER---REKKSLRWVRAIKTPVS 21554
Query: 3007 SF--DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
L++G Y FRV+ NR G G S+ S S+ + A P P +
Sbjct: 21555 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPG-----PPSNPHVT 21609
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVE-EEAG--RMTSQFNGFDCCLT---IKDINIDD 3118
T GKP G+ VE ++ G G +T + D+ +
Sbjct: 21610 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKE 21669
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
+ + A N G AV+ D + ++RE + + E D + T+ +R
Sbjct: 21670 KYNFRISAINDAGVGEP----AVIPDVEI------VEREMAPDFELDAELRRTLVVR--- 21716
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
A +R+ + G P P+V+W KD + R N E F L I N D G +
Sbjct: 21717 --AGLSIRIFVPIKGRPAPEVTWTKD--NINLKNRANIENTESFTLLIIPECNRYDTGKF 21772
Query: 3239 EVTARNNSGAVS 3250
+T N +G S
Sbjct: 21773 VMTIENPAGKKS 21784
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/249 (22%), Positives = 107/249 (42%), Gaps = 32/249 (12%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
++ L +G EY FRV N YG GE ++T+ + A P+ ++I+ +
Sbjct: 21852 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMD-----ITKS 21906
Query: 3067 TANLTCSVK----GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
T +L G + G V ++ + ++ +T+ G +C ++++ +E +
Sbjct: 21907 TVSLAWPKPKHDGGSKITGYV-IEAQRKGSDQWTHITT-VKGLEC--VVRNLTEGEEYTF 21962
Query: 3123 SCEATNTHGK-ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
A N+ G+ A +R +V ++T+ ++ G Y + D
Sbjct: 21963 QVMAVNSAGRSAPRESRPVIVKEQTMLP---------ELDLRGIYQKLVIAKAGDN---- 22009
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEV 3240
+++ V+G P P V+W K G++++ +R ++ T L I D G Y +
Sbjct: 22010 ---IKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 22065
Query: 3241 TARNNSGAV 3249
TARN G V
Sbjct: 22066 TARNIVGEV 22074
Score = 50.4 bits (115), Expect = 1e-04
Identities = 80/330 (24%), Positives = 123/330 (37%), Gaps = 47/330 (14%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTT--APVLAYKVESWLIGAEGGARWVEL 3000
P VP+ P P +VD ++ VSL W +DP+ T +P+ Y +E W
Sbjct: 21099 PFDVPDA-PPPPNIVDVRHDSVSLTW--TDPKKTGGSPITGYHLE---FKERNSLLWKRA 21152
Query: 3001 GITPLN--SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL----AGDRPEFVD 3054
TP+ F L +G EY FRV N G G+ S S + V L +PE ++
Sbjct: 21153 NKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPV-VALDPIDPPGKPEVIN 21211
Query: 3055 ILPGQLKILAGETA-----NLT-CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
I + ++ E LT V+ + +P WMK H N +C
Sbjct: 21212 ITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANH------------VNVPECA 21259
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYAR-LAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
T+ D+ + + A NT G S + + + +EA + ++
Sbjct: 21260 FTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP-------TIVLDPTIK 21312
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
T++ D V ++G P PK SW K G+++ L I
Sbjct: 21313 DGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTI 21366
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
D G Y +TA N G H + V
Sbjct: 21367 KYATRKDAGEYTITATNPFGTKVEHVKVTV 21396
Score = 50.0 bits (114), Expect = 1e-04
Identities = 56/206 (27%), Positives = 89/206 (43%), Gaps = 33/206 (16%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
E +TS+ + V G R +F+ L Q + GETA C + + + VVW KN ++
Sbjct: 12486 EGKKTSARLFV--TGIRLKFMSPLEDQT-VKEGETATFVCELSHEKMH-VVWFKNDAKLH 12541
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
+ S G L +K++ +DD + + + S+ A+L V+ EAD
Sbjct: 12542 TSRTVLISS-EGKTHKLEMKEVTLDDISQIKAQVK----ELSSTAQLKVL------EAD- 12589
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
P FT++L D+ + L C+V P V W+KDGEE+V
Sbjct: 12590 ---------------PYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSP 12632
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ + D L+I +L D G Y
Sbjct: 12633 KYSIKADGLRRILKIKKADLKDKGEY 12658
Score = 50.0 bits (114), Expect = 1e-04
Identities = 79/348 (22%), Positives = 131/348 (37%), Gaps = 37/348 (10%)
Query: 2915 IVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGN---NWVSLAWPKS 2971
++ E +S + +P + +P P + + N N ++L W +
Sbjct: 29043 LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP 29102
Query: 2972 DPQTTAPVLAYKVESWLIGAEGGARWVE-LGITPLNS--FDAFNLKQGEEYHFRVTPRNR 3028
+ + + Y +E + RWV+ + P++ F L +G EY F V N
Sbjct: 29103 ESDGGSEIQQYILER---REKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENA 29159
Query: 3029 YGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVK-GKPVPGVVWMKN 3087
G G +S S I + P P +K+ +T+ T S++ KPV
Sbjct: 29160 AGVGPASGISRLIKCREPVNPPG----PPTVVKVT--DTSKTTVSLEWSKPVFDGGMEII 29213
Query: 3088 GHEVEEEAGRMTS--QFNGFDCC---LTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
G+ +E + + N C T+ D+ +E ++ A N GK + V
Sbjct: 29214 GYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDS----CEV 29269
Query: 3143 TDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWY 3202
T T+ D R E D F + V+A +RL G P P W
Sbjct: 29270 TG-TIKAVD------RLTAPELDIDANFK---QTHVVRAGASIRLFIAYQGRPTPTAVWS 29319
Query: 3203 KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
K + R + + + F TL + N +D G Y +T NNSG+ S
Sbjct: 29320 KPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKS 29365
Score = 49.6 bits (113), Expect = 2e-04
Identities = 65/247 (26%), Positives = 97/247 (39%), Gaps = 30/247 (12%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI--LA 3064
SF NL G EY+FRVT N YG G + + LA D D P +L++ +
Sbjct: 19683 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPV---LASDPLSEPDP-PRKLEVTEMT 19738
Query: 3065 GETANLTCSVK----GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+A L G + G ++ + E E+ A R T D L + + +
Sbjct: 19739 KNSATLAWLPPLRDGGAKIDG--YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKY 19796
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
++ A N G + R A V+EA +L PP+ M ++
Sbjct: 19797 KFRVAARNAVGVS--LPREA----EGVYEAKEQL-----------LPPKILMP-EQITIK 19838
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
A +R+ V G P P W K +EVV ++ + L I D G Y +
Sbjct: 19839 AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSL 19898
Query: 3241 TARNNSG 3247
TA N+SG
Sbjct: 19899 TAENSSG 19905
Score = 49.2 bits (112), Expect = 3e-04
Identities = 48/184 (26%), Positives = 84/184 (45%), Gaps = 17/184 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT-L 2651
K + LT+ V GS C ++S S TW ++G + K+R + DG L
Sbjct: 12046 KEIKDIILTESEFV-GSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRF-IADGKDRKL 12102
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE- 2710
+++ SD+ EY+C + N +++A L V +P F +++ + + + +
Sbjct: 12103 HIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV------EELPVRFVKTLEEEVTVVKGQP 12156
Query: 2711 LVLECRIRGQPLPKITWFKDDK-QIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCK 2768
L L C + + + W KD K + GR + G+ R L I++ D+GTYT
Sbjct: 12157 LYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVI--GLMRALTINDADDTDAGTYTVT 12212
Query: 2769 AENS 2772
EN+
Sbjct: 12213 VENA 12216
Score = 49.2 bits (112), Expect = 3e-04
Identities = 51/191 (26%), Positives = 71/191 (37%), Gaps = 12/191 (6%)
Query: 2962 NWVSLAWPKSDPQTTAPVLAYKVE--SWLIGAEGGARWVELGITPLNS--FDAFNLKQGE 3017
N V L+W +PV Y VE +W W + + F +L +G
Sbjct: 16953 NTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGG 17012
Query: 3018 EYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGK 3077
EY FRV N G + S T D P +D L +++ G N+ +KG
Sbjct: 17013 EYEFRVKAVNAAGVSKPSATVGPCDCQRP-DMPPSID-LKEFMEVEEGTNVNIVAKIKGV 17070
Query: 3078 PVPGVVWMKNGHEV--EEEAGRMTSQFNGF----DCCLTIKDINIDDEGRYSCEATNTHG 3131
P P + W K + +E + N C L I D G Y+ A N G
Sbjct: 17071 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 17130
Query: 3132 KASTYARLAVV 3142
AS RL V+
Sbjct: 17131 TASKEMRLNVL 17141
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/305 (22%), Positives = 111/305 (36%), Gaps = 29/305 (9%)
Query: 2961 NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR-WVELGITPLN-SFDAFNLKQGEE 3018
N L W + +P+ Y +E E R W + T + L QG+
Sbjct: 17557 NESCKLTWFSPEDDGGSPITNYVIEK----RESDRRAWTPVTYTVTRQNATVQGLIQGKA 17612
Query: 3019 YHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKP 3078
Y FR+ N G G +TS ++ + PE + L ++K + T LT +
Sbjct: 17613 YFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDL--EVKEVTKNTVTLTWNPPKYD 17670
Query: 3079 VPGVV--WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
+ ++ + E + N T+K + D Y A N G+
Sbjct: 17671 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPS 17730
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRLTCQVIGSP 3195
+T K E + PP + RD+ ++ LT + G P
Sbjct: 17731 FCTKPIT----------CKDELA-------PPTLHLDFRDKLTIRVGEAFALTGRYSGKP 17773
Query: 3196 PPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL 3255
PKVSW+KD +V+ D R + LE D G Y V N++G+ C +
Sbjct: 17774 KPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQV 17833
Query: 3256 -VVDK 3259
VVD+
Sbjct: 17834 NVVDR 17838
Score = 49.2 bits (112), Expect = 3e-04
Identities = 55/252 (21%), Positives = 106/252 (42%), Gaps = 24/252 (9%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
+F NL++G Y+FRV N YG G ++T+ + V + P + PG++ ++ +
Sbjct: 26183 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS---EPP----LPPGRVTLV--D 26233
Query: 3067 TANLTCSVKG-KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
T ++K KP G+ VE + T + C +K + G
Sbjct: 26234 VTRNTATIKWEKPESDGGSKITGYVVEMQ----TKGSEKWSTCTQVKTLEATISGL---- 26285
Query: 3126 ATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPV 3185
T G+ + R+A V ++ +D + + + P + V+A +
Sbjct: 26286 ---TAGEEYVF-RVAAVNEKG--RSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 26339
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
++ G P V+W KDG+ + R N + +L I + +D G YE+ N+
Sbjct: 26340 KIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 26399
Query: 3246 SGAVSCHCGLVV 3257
+G+++ ++V
Sbjct: 26400 AGSITVPITIIV 26411
Score = 48.8 bits (111), Expect = 3e-04
Identities = 80/323 (24%), Positives = 126/323 (39%), Gaps = 49/323 (15%)
Query: 2950 IPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT-PL 3005
+PG P V D L+W D + Y +E I G W ++
Sbjct: 16838 VPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTID---GKAWTKVNPDCGS 16894
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI--L 3063
+F +L ++Y FRV NR+G G +T I A D P + P +LKI +
Sbjct: 16895 TTFVVPDLLSEQQYFFRVRAENRFGIGPPVET---IQRTTARD-PIYPPDPPIKLKIGLI 16950
Query: 3064 AGETANLTCSVK----GKPVPGVV-----WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
T +L+ G PV + W G ++EA R ++ + + T++D+
Sbjct: 16951 TKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTG--TKKEAWRQCNKRDVEELQFTVEDL 17008
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
E + +A N G + A TV D + D PP ++
Sbjct: 17009 VEGGEYEFRVKAVNAAGVSKPSA--------TVGPCDCQ---------RPDMPPSIDLK- 17050
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYK-------DGEEVVYDKRRNKYQDEQFHTLEI 3227
V+ V + ++ G P P ++W+K + E V+YD NK + TL I
Sbjct: 17051 EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVI 17110
Query: 3228 APTNLDDGGVYEVTARNNSGAVS 3250
+ D G+Y +TA NN G S
Sbjct: 17111 PQSRRSDTGLYTITAVNNLGTAS 17133
Score = 48.8 bits (111), Expect = 3e-04
Identities = 52/191 (27%), Positives = 78/191 (40%), Gaps = 20/191 (10%)
Query: 2951 PGEPCVVDGGNNWVSLAW--PKSD--PQTTAPVLAYKVES---WLIGAEGGARWVELGIT 3003
P P V D + L W P D + T ++ YK E W G + R +L +T
Sbjct: 17351 PPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVT 17410
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLK 3061
LK+G Y FRV+ N G GE + + I + P+ +D + ++
Sbjct: 17411 --------GLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV 17462
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AG + V GKP P V W N + +EA T + + IK+ +G
Sbjct: 17463 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQGV 17519
Query: 3122 YSCEATNTHGK 3132
YS A N G+
Sbjct: 17520 YSLLAKNEAGE 17530
Score = 48.8 bits (111), Expect = 3e-04
Identities = 72/325 (22%), Positives = 127/325 (39%), Gaps = 34/325 (10%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG+P + + ++ +SL W + V + VE W ++ +P++ +
Sbjct: 28687 PGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEK---KERNSILWQKVNTSPISGREY 28743
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETA 3068
A L +G +Y FRV N G S S D P D + + ET
Sbjct: 28744 RATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYID-----VTRETI 28798
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEEAGR---MTSQFNGF-DCCLTIKDINIDDEGRYSC 3124
L + P+ G+ +E+ G + F +C T+ ++ D +
Sbjct: 28799 TLKWN---PPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRI 28855
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G S ++ + + + R+ + ++ P++ L +++
Sbjct: 28856 IARNAVGTISPPSQSSGII----------MTRDENVPPIVEFGPEYFDGLI---IKSGES 28902
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHT-LEIAPTNLDDGGVYEVTA 3242
+R+ V G P P+V+W+KDG E+ +KR N + D T L + D GVY V A
Sbjct: 28903 LRIKALVQGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 28960
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAP 3267
+N SG+ + V V P
Sbjct: 28961 KNASGSAKAEIKVKVQDTPGKVVGP 28985
Score = 48.4 bits (110), Expect = 5e-04
Identities = 60/221 (27%), Positives = 90/221 (40%), Gaps = 38/221 (17%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EF+ P L+IL GE A CS+ + P V W K + E + +G L
Sbjct: 13480 EFIS-KPQNLEILEGEKAEFVCSISKESFP-VQW-KRDDKTLESGDKYDVIADGKKRVLV 13536
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+KD + D G Y G A A L V+ KL+
Sbjct: 13537 VKDATLQDMGTYVVMV----GAARAAAHLTVIE---------KLR--------------I 13569
Query: 3171 TMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY---QDEQFHTLEI 3227
+ L+D RV+ V C+V + K W+++ EE ++D +KY Q + +TL I
Sbjct: 13570 VVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRN-EEAIFDS--SKYIILQKDLVYTLRI 13625
Query: 3228 APTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAP 3267
+LDD Y V+ N+ G V L+V++ V P
Sbjct: 13626 RDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEP 13666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
++ L + G + + A V P V+W +DG L+P+ M + R+ L L +V
Sbjct: 20228 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVN 20286
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
+D+G YT TA N G S + K++V+ D+ PP + + YS M +P
Sbjct: 20287 RKDSGDYTITAENSSGSKSATIKLKVL--DKPG----PPASVKINKMYSDRAMLSWEP 20338
Score = 48.0 bits (109), Expect = 6e-04
Identities = 40/143 (27%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT-VENENGAISTSANLKV 2683
V WY++G+ + KYR + L +L SD+ +YSC VE+EN + T+A L V
Sbjct: 2205 VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN--VKTTAKLIV 2262
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
E + + F + ++D LEC + + + + W+ +D ++ S+G+Y
Sbjct: 2263 ----EGAVV--EFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKY-TI 2314
Query: 2744 YLADGVCRLAIDNPTPEDSGTYT 2766
G L + + T ED G Y+
Sbjct: 2315 TSRRGRQNLTVKDVTKEDQGEYS 2337
Score = 47.6 bits (108), Expect = 8e-04
Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A V L V G P P VSW KDG + + TLE+ N D G Y
Sbjct: 20234 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 20293
Query: 3239 EVTARNNSGAVSCHCGL-VVDK 3259
+TA N+SG+ S L V+DK
Sbjct: 20294 TITAENSSGSKSATIKLKVLDK 20315
Score = 47.2 bits (107), Expect = 0.001
Identities = 79/330 (23%), Positives = 122/330 (36%), Gaps = 52/330 (15%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++ +S + + EF+ L L++ E A C + + V W K+G E++
Sbjct: 13284 DAKDFKTSCNLNVVPPHVEFLRPLT-DLQVREKEMARFECELSRENAK-VKWFKDGAEIK 13341
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
+ + G L I +DDE YSCE A T L V+ + V
Sbjct: 13342 K-GKKYDIISKGAVRILVINKCLLDDEAEYSCEVRT----ARTSGMLTVLEEEAV----- 13391
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
FT L + V T ++L C+V P +V WYK EE++
Sbjct: 13392 -----------------FTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETG 13433
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
R + + L I +L+D G Y + + G V H +A EF
Sbjct: 13434 RYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-----------ELAAEFI 13482
Query: 3271 CGLEPLYKLH-EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
+ L L E E S E++P V W RD L + + D ++ L +
Sbjct: 13483 SKPQNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVK 13538
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
T +D G Y VG A + + VI
Sbjct: 13539 DATLQDMGTYVVM----VGAARAAAHLTVI 13564
Score = 47.2 bits (107), Expect = 0.001
Identities = 72/265 (27%), Positives = 106/265 (40%), Gaps = 45/265 (16%)
Query: 3003 TPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI 3062
T + D L +G+EY FRV +N++G G + IG LA D P P +L
Sbjct: 16176 TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVE----IGPILAVD-PLGPPTSPERLTY 16230
Query: 3063 LAGETANLTCSVK------GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI-- 3114
+ +T K G P+ G + K H+ + + R+ + C T +
Sbjct: 16231 TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHD-KPDFERVNKRL-----CPTTSFLVE 16284
Query: 3115 NIDDEGRYS--CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
N+D+ Y +A N G++ L VV KL+ V GD T+
Sbjct: 16285 NLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLR----LSVRGD-----TI 16335
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ--------DEQFHT 3224
+V+A PV + V G P PK+ W K+ E V +K + Q E
Sbjct: 16336 -----KVKAGEPVHIPADVTGLPMPKIEWSKN--ETVIEKPTDALQITKEEVSRSEAKTE 16388
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAV 3249
L I +D G Y VTA N G+V
Sbjct: 16389 LSIPKAVREDKGTYTVTASNRLGSV 16413
Score = 47.2 bits (107), Expect = 0.001
Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
Y + G +L+I + P +TW +DG+ L+ + R +T D L++ D
Sbjct: 24166 YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLDLTTLSIKETHKDDG 24224
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
G Y T +N VG+ + S +E++ D+ P+ P
Sbjct: 24225 GQYGITVANVVGQKTAS--IEIVTLDKPDPPKGP 24256
Score = 46.8 bits (106), Expect = 0.001
Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 18/162 (11%)
Query: 3198 KVSWYKDGEEVVYDKRRNKYQDE-QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
+V W+K+ + + + R QDE + H++ ++DD V A +S L
Sbjct: 12885 RVKWFKNDQRL-HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMG----MSSEAKLT 12939
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIM 3316
V +G P F L+ Y E DE+ + + V W++DG ++PS+ A++
Sbjct: 12940 VLEG-----DPYFTGKLQD-YTGVEKDEVILQCEISK-ADAPVKWFKDGKEIKPSKNAVI 12992
Query: 3317 TLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
D ++ L L D G YTC + G TSGK+++
Sbjct: 12993 KADGKKRM-LILKKALKSDIGQYTC----DCGTDKTSGKLDI 13029
Score = 46.8 bits (106), Expect = 0.001
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG+P V D G V L W K + A + +Y +E G + R E G+ P
Sbjct: 14914 PGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAE-GV-PTTQHLL 14971
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
L +G+EY FRV N+ G E S+ S +
Sbjct: 14972 PGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 15002
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P T L D EG + C V S +D V+WY + +R + LE+
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A P D Y+ N G +S++ANL +
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 46.4 bits (105), Expect = 0.002
Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 18/199 (9%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGI 3002
P PER+ + + ++L W + +P+ Y +E R V +
Sbjct: 16221 PPTSPERLT----YTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFER-VNKRL 16275
Query: 3003 TPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF---VDILP 3057
P SF NL + + Y FRV N G S+ S + V + D P + +
Sbjct: 16276 CPTTSFLVENLDEHQMYEFRVKAVNEIG---ESEPSLPLNVVIQDDEVPPTIKLRLSVRG 16332
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQ---FNGFDCCLTIK 3112
+K+ AGE ++ V G P+P + W KN +E+ +A ++T + + L+I
Sbjct: 16333 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 16392
Query: 3113 DINIDDEGRYSCEATNTHG 3131
+D+G Y+ A+N G
Sbjct: 16393 KAVREDKGTYTVTASNRLG 16411
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 8/137 (5%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
+++ PS EA P F R T ++ R+ G+P P+ W+K+ +I R
Sbjct: 2069 IELSPSMEA---PKIFERIQSQTVGQG-SDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2124
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVV 2796
++ D VC L I + T EDS + KA N F+ ++ +Q +VV
Sbjct: 2125 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVV 2184
Query: 2797 TAEKTRIARQSLESRRP 2813
EK +A E+ P
Sbjct: 2185 AKEKDTMATFECETSEP 2201
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD LR+SA+++ P VTW ++ R P++ I ++E+ AA D G+Y+
Sbjct: 18160 GDTLRLSAIIKGVPFPKVTWKKED-RDAPTKARIDVTPVGSKLEIRNAA--HEDGGIYSL 18216
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPR 3368
T N G + S KV V+ D+ PR
Sbjct: 18217 TVENPAGSKTVSVKVLVL--DKPGPPR 18241
Score = 45.6 bits (103), Expect = 0.003
Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 23/254 (9%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
S+ L++G Y+FRV N YG G ++T+ S+ A +RP + PG++ ++
Sbjct: 22936 SWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVK---ASERP----LPPGKITLMDVT 22988
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
+++ S + KP G+ VE + T + + C T+K G
Sbjct: 22989 RNSVSLSWE-KPEHDGGSRILGYIVEMQ----TKGSDKWATCATVKVTEATITGLIQ--- 23040
Query: 3127 TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVR 3186
G+ ++ R++ ++ + +D + + PP F + V A ++
Sbjct: 23041 ----GEEYSF-RVSAQNEKGI--SDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 23093
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
+ IG P P V+W+KD + R N E L I +D G Y V N++
Sbjct: 23094 VDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSA 23153
Query: 3247 G-AVSCHCGLVVDK 3259
G A+ +V+DK
Sbjct: 23154 GEAIETLNVIVLDK 23167
Score = 45.2 bits (102), Expect = 0.004
Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 5/108 (4%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLD 2635
S ISE ++++ KP D +EG ++ + + PTV+W+++G V
Sbjct: 15299 SEISEN-VVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS 15357
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
++L + + LEV +V +D+ Y+ T+EN+ G+ + S N+KV
Sbjct: 15358 DRLTMKNDHISA--HLEVPKSVRADAGIYTITLENKLGSATASINVKV 15403
Score = 45.2 bits (102), Expect = 0.004
Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 8/160 (5%)
Query: 2652 EVLNAVPSDSAEYSCTVENENGAIS--TSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
EV V E+ N G S + + + E P + +DT +
Sbjct: 23426 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAG 23485
Query: 2710 E-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
E ++ I G+P+P I W K D+++ + R + D L++ + DSG Y K
Sbjct: 23486 ESFKVDADIYGKPIPTIQWIKGDQELSNTARLE-IKSTDFATSLSVKDAVRVDSGNYILK 23544
Query: 2769 AENSVWTDQITHFVNFTGR----ESQVSPNVVTAEKTRIA 2804
A+N +T V R E V + VTAEK +A
Sbjct: 23545 AKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLA 23584
Score = 45.2 bits (102), Expect = 0.004
Identities = 76/309 (24%), Positives = 119/309 (38%), Gaps = 34/309 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P V + + + W + ++ Y +E + WV+L TP+ F
Sbjct: 25435 PGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ---KEKNSILWVKLNKTPIQDTKF 25491
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETA 3068
L +G EY F+V+ N G G+ S+ S +A D + PG+ + +
Sbjct: 25492 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF---VARDPCD----PPGRPEAIVITRN 25544
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEE---AGR-MTSQF-NGFDCCLTIKDINIDDEGRYS 3123
N+T K KP G+ VE++ GR M + F N + T+ + D +
Sbjct: 25545 NVTLKWK-KPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFR 25603
Query: 3124 CEATNTHGKASTYA-RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
A N G S + +T R E DA +A ++ Y + + V
Sbjct: 25604 VIARNAAGNFSEPSDSSGAITARD--EIDAP-----NASLDPKYKDVIVVHAGETFV--- 25653
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE-QFHTLEIAPTNLDDGGVYEVT 3241
L + G P P V W KDG+E+ R + + Q TL + DGG Y +
Sbjct: 25654 ----LEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILK 25709
Query: 3242 ARNNSGAVS 3250
N G S
Sbjct: 25710 LSNVGGTKS 25718
Score = 45.2 bits (102), Expect = 0.004
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 2/86 (2%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL- 3005
P PG P V D + VSL W + V+ Y +E + G RW++ T +
Sbjct: 29865 PVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 29924
Query: 3006 -NSFDAFNLKQGEEYHFRVTPRNRYG 3030
N F L +G+ Y FRV +N G
Sbjct: 29925 DNFFTVTALSEGDTYEFRVLAKNAAG 29950
Score = 44.8 bits (101), Expect = 0.006
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
Score = 44.8 bits (101), Expect = 0.006
Identities = 49/167 (29%), Positives = 74/167 (44%), Gaps = 19/167 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGL-ITLE 2652
P F+ L D+TAVE + L C V S D V W+++G + KY K DGL L+
Sbjct: 12590 PYFTVKLHDKTAVEKDEITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIK-ADGLRRILK 12646
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFH----LA 2707
+ A D EY C + G T AN+ V P + +T H L+
Sbjct: 12647 IKKADLKDKGEYVC----DCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELS 12702
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
E ++ + +++GQPL D +I DG+ L + C+L +
Sbjct: 12703 EPDVHGQWKLKGQPLTA----SPDCEIIEDGKKHILILHN--CQLGM 12743
Score = 44.8 bits (101), Expect = 0.006
Identities = 77/309 (24%), Positives = 123/309 (39%), Gaps = 35/309 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P + + + W + +PV+ Y +E W ++ T ++ F
Sbjct: 24353 PGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER---KERNSILWTKVNKTIIHDTQF 24409
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE-T 3067
A NL++G EY FRV N G G++S+ S D P P + + E T
Sbjct: 24410 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG----TPEPIMVKRNEIT 24465
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEE---AGR-MTSQF-NGFDCCLTIKDINIDDEGRY 3122
T KPV M G+ VE+ GR M + F N + T+ + D +
Sbjct: 24466 LQWT-----KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEF 24520
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
A N G S + + T + + +L R + D P+F + V A
Sbjct: 24521 RVIAKNAAGAIS---KPSDSTGPITAKDEVELPR-----ISMD--PKFRDTI---VVNAG 24567
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD-DGGVYEVT 3241
RL V G P P + W + G++ + + R + ++ F L I + DGG Y +
Sbjct: 24568 ETFRLEADVHGKPLPTIEWLR-GDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILR 24626
Query: 3242 ARNNSGAVS 3250
A N +G+ S
Sbjct: 24627 ASNVAGSKS 24635
Score = 44.4 bits (100), Expect = 0.007
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 12/137 (8%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELV-LECRI 2717
+ EY V+ N A + + V P P +PP+ +++ + E V + +I
Sbjct: 17010 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSI--DLKEFMEVEEGTNVNIVAKI 17067
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFY-------LADGVCRLAIDNPTPEDSGTYTCKAE 2770
+G P P +TWFK + P D + Y + D C L I D+G YT A
Sbjct: 17068 KGVPFPTLTWFKAPPKKP-DNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAV 17126
Query: 2771 NSVWTDQITHFVNFTGR 2787
N++ T +N GR
Sbjct: 17127 NNLGTASKEMRLNVLGR 17143
Score = 44.4 bits (100), Expect = 0.007
Identities = 42/140 (30%), Positives = 66/140 (47%), Gaps = 15/140 (10%)
Query: 3230 TNLDDGGVYE--VTARNNSGAVSC---HCGLVVDKGIRAYVAPEFCCGLEPLYK----LH 3280
T+L +GG YE + A+N +GA+S ++ K Y AP L+P K +
Sbjct: 21263 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKD--EYEAPTIV--LDPTIKDGLTIK 21318
Query: 3281 EGDELRISAV-VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
GD + ++A+ + P +W + G +RPS +T + L + T +DAG Y
Sbjct: 21319 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM-LTIKYATRKDAGEY 21377
Query: 3340 TCTASNEVGRASTSGKVEVI 3359
T TA+N G KV V+
Sbjct: 21378 TITATNPFGTKVEHVKVTVL 21397
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+P+ V + P +++L GETA C V G P P V W NG ++ ++ R +++G
Sbjct: 1840 KPDIV-LYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIH-Y 1896
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I D D G A N G +L +
Sbjct: 1897 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 44.0 bits (99), Expect = 0.010
Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 16/212 (7%)
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +K VEG +F L+D V +Y L C ++ + WY + E+
Sbjct: 2251 DENVKTTAKLIVEGAVV-EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKS 2308
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+ + L + +D G Y C L + A +
Sbjct: 2309 NGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT----CKLKMKPRPIAILQ---- 2360
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL K+ EGD +++ V GV W +DG ++PS R + +D+ + L +
Sbjct: 2361 -GLSD-QKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHM-LLIED 2416
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+T DAG Y+ T +G STSG+V V D
Sbjct: 2417 MTKEDAGNYSFTIP-ALG-LSTSGRVSVYSVD 2446
Score = 44.0 bits (99), Expect = 0.010
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 7/118 (5%)
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L L I+G P PK+TW K+D+ P+ R + +L I N ED G Y+ E
Sbjct: 18163 LRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS---KLEIRNAAHEDGGIYSLTVE 18219
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP--HFGNVLTDYQVAR 2826
N + ++ V + P + + R L + P G+V+T+Y V R
Sbjct: 18220 NPAGSKTVS--VKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVER 18275
Score = 44.0 bits (99), Expect = 0.010
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 2/120 (1%)
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + + + + +NE G IS L V + IPP F LA +L
Sbjct: 23035 ITGLIQGEEYSFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 23093
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
++ G+P P +TW KD+ + R A + L I + ED G Y K NS
Sbjct: 23094 VDVPFIGRPTPAVTWHKDNVPLKQTTRVNA-ESTENNSLLTIKDACREDVGHYVVKLTNS 23152
Score = 44.0 bits (99), Expect = 0.010
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+G+P P +TW KD+K + SD RY + D L I T D+G Y EN V
Sbjct: 28223 KGRPPPTVTWRKDEKNLGSDARY-SIENTDSSSLLTIPQVTRNDTGKYILTIENGV 28277
Score = 43.6 bits (98), Expect = 0.013
Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P F ++ G T +++ G P W +G+ + Y + V E G +L
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
+ T ++SG +T A + G ++ +T V+ + KP + K++ I G
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFV--EKLKNVNIKEGSQ 1572
Query: 2931 INISFRTQGEPKPKAV 2946
+ + R G P P V
Sbjct: 1573 LEMKVRATGNPNPDIV 1588
Score = 43.2 bits (97), Expect = 0.017
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L+D+ EG V+L V S V W ++G + + + L + +
Sbjct: 2362 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKE 2420
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ YS T+ +STS + VY +P+ +D + + VLEC++
Sbjct: 2421 DAGNYSFTIPALG--LSTSGRVSVYSVDVITPL--------KDVNVIEGTKAVLECKVSV 2470
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ + W+ +D+QI D R QA + RL I+ D G Y
Sbjct: 2471 PDVTSVKWYLNDEQIKPDDRVQAI-VKGTKQRLVINRTHASDEGPY 2515
Score = 43.2 bits (97), Expect = 0.017
Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCR- 2751
P FT ++D + ++E++L+C I P + WFKD K+I PS A ADG R
Sbjct: 12945 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSK---NAVIKADGKKRM 13000
Query: 2752 LAIDNPTPEDSGTYTC 2767
L + D G YTC
Sbjct: 13001 LILKKALKSDIGQYTC 13016
Score = 43.2 bits (97), Expect = 0.017
Identities = 57/243 (23%), Positives = 91/243 (37%), Gaps = 26/243 (10%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
SF NL++G+ Y FRV N YG G+ +T ++ A P V LK+ +
Sbjct: 20771 SFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVK---ASQTPGPVV----DLKVRSVS 20823
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
++ + K KP G+ V+ E + + KD+ E +
Sbjct: 20824 KSSCSIGWK-KPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRV 20882
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N +G+ T + + VV V D LK P + + + P
Sbjct: 20883 SAENENGEG-TPSEITVVARDDVVAPDLDLK---------GLPDLCYLAKENSNFRLKIP 20932
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
++ G P P VSW K + + D R + TL + D G Y +T +N
Sbjct: 20933 IK------GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 20986
Query: 3245 NSG 3247
+G
Sbjct: 20987 VAG 20989
Score = 42.7 bits (96), Expect = 0.022
Identities = 58/243 (23%), Positives = 93/243 (38%), Gaps = 36/243 (14%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+D ++DD+ Y+ TN G+ A +V E D ++ E ++E
Sbjct: 13623 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVE-----EEDLRIV-EPLKDIETMEKK 13676
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
T + R+ T + W K+GEEV +D R + D+ H L I
Sbjct: 13677 SVTFWCKVNRLNVT----------------LKWTKNGEEVPFDNRVSYRVDKYKHMLTIK 13720
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
D G Y VTA + L+++ EF LE + E D+ S
Sbjct: 13721 DCGFPDEGEYIVTAGQDKSVAEL---LIIE------APTEFVEHLED-QTVTEFDDAVFS 13770
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASNEV 3347
+ + V WYR+G ++ ++ ++DG I L + D Y C +
Sbjct: 13771 CQL-SREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDECEYACGVEDRK 13827
Query: 3348 GRA 3350
RA
Sbjct: 13828 SRA 13830
Score = 42.7 bits (96), Expect = 0.022
Identities = 42/156 (26%), Positives = 59/156 (37%), Gaps = 3/156 (1%)
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
DN ++ KLV L T +V + Y + EN+ G S L + +A P
Sbjct: 14263 DNWIRCNMKLVPEL-TYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPT 14321
Query: 2695 TFTRSIRDTFH-LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ +D + N + + G P P TW DK + + R + L+ L
Sbjct: 14322 MDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS-AYAELV 14380
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
I D G YT K EN V T VN R S
Sbjct: 14381 ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPS 14416
Score = 42.7 bits (96), Expect = 0.022
Identities = 21/63 (33%), Positives = 30/63 (47%)
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
P P VSW+KDG+EV R D LE+ + D G+Y +T N G+ +
Sbjct: 15341 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 15400
Query: 3255 LVV 3257
+ V
Sbjct: 15401 VKV 15403
Score = 42.7 bits (96), Expect = 0.022
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASP--IPPTFTRSIRDTFHLAENELVLECRI 2717
+ +Y V N A+ S + +EA +PP + T A +L +E +
Sbjct: 19792 EGKKYKFRVAARN-AVGVSLPREAEGVYEAKEQLLPPKILMPEQITIK-AGKKLRIEAHV 19849
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G+P P W K + ++ + + A + AD L I + T +DSG Y+ AENS TD
Sbjct: 19850 YGKPHPTCKWKKGEDEVVTSS-HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTD 19907
Score = 42.7 bits (96), Expect = 0.022
Identities = 30/118 (25%), Positives = 51/118 (43%), Gaps = 4/118 (3%)
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT--FTRSIRDTFHLAENE-LVLE 2714
P D E+ N G IS + +PP F D + E L ++
Sbjct: 28847 PGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIK 28906
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
++G+P+P++TWFKD +I + + G L + + T + G YT +A+N+
Sbjct: 28907 ALVQGRPVPRVTWFKDGVEIEKRMNMEITDVL-GSTSLFVRDATRDHRGVYTVEAKNA 28963
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 18/184 (9%)
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P K+SWYK E++ + D HTL + L D G Y +
Sbjct: 9608 INYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLV---------- 9657
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
CG + + P + L+ + L EG ++ + P+V W+R+G L+P
Sbjct: 9658 -CGPHIASAKLTVIEPAWERHLQDV-TLKEGQTCTMTCQF-SVPNVKSEWFRNGRILKPQ 9714
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R ++ +L +A V D G YTC + TS ++ + RI
Sbjct: 9715 GRHKTEVEHKVH-KLTIADVRAEDQGQYTCKYED----LETSAELRIEAEPIQFTKRIQN 9769
Query: 3372 VVIS 3375
+V+S
Sbjct: 9770 IVVS 9773
Score = 42.3 bits (95), Expect = 0.030
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 2685 PSFEASPI-------PPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPS 2736
PSF PI PPT RD + E L R G+P PK++WFKD+ +
Sbjct: 17729 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 17788
Query: 2737 DGRYQAFYLADGVCRLAID--NPTPEDSGTYTCKAENS 2772
D R ++ LA++ DSG Y ENS
Sbjct: 17789 DDR---THIKTTPATLALEKIKAKRSDSGKYCVVVENS 17823
Score = 41.9 bits (94), Expect = 0.039
Identities = 40/171 (23%), Positives = 70/171 (40%), Gaps = 15/171 (8%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN 2655
F L D+T E +C +S V WYRNG + KY+ + + L + +
Sbjct: 13752 FVEHLEDQTVTEFDDAVFSCQ-LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 13810
Query: 2656 AVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLEC 2715
D EY+C VE+ + A L V IP R +D ++V
Sbjct: 13811 CRLDDECEYACGVEDR----KSRARLFV------EEIPVEIIRPPQDILEAPGADVVFLA 13860
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTY 2765
+ + ++ W +++ + ++Q +++G + RL I + P D G Y
Sbjct: 13861 ELNKDKV-EVQWLRNNMVVVQGDKHQ--MMSEGKIHRLQICDIKPRDQGEY 13908
Score = 41.9 bits (94), Expect = 0.039
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 2689 ASPIPPTFTRSIRDTFHL---AENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFY 2744
A +PP S+ L A + L+ + G+P+P ++W KD + P++G A
Sbjct: 20215 AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMA-- 20272
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ +C L + + +DSG YT AENS
Sbjct: 20273 MQRNLCTLELFSVNRKDSGDYTITAENS 20300
Score = 41.5 bits (93), Expect = 0.052
Identities = 45/171 (26%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR--SIR-DTFHLAENELV-LECRIR 2718
E+ NE G S L V + +PPT S+R DT + E V + +
Sbjct: 16293 EFRVKAVNEIGESEPSLPLNVV--IQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVT 16350
Query: 2719 GQPLPKITWFKDDKQI--PSDG---RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
G P+PKI W K++ I P+D + ++ L+I ED GTYT A N +
Sbjct: 16351 GLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 16410
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
+ V R S VT K + ++ + G+ +T Y +
Sbjct: 16411 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 16461
Score = 41.5 bits (93), Expect = 0.052
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 2961 NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS-FDAFNLKQGEEY 3019
+++V+ +W + P+ Y VE + WVEL T + + + A L G EY
Sbjct: 22100 SDFVTFSWDPPENDGGVPISNYVVE---MRQTDSTTWVELATTVIRTTYKATRLTTGLEY 22156
Query: 3020 HFRVTPRNRYGWG 3032
FRV +NRYG G
Sbjct: 22157 QFRVKAQNRYGVG 22169
Score = 41.1 bits (92), Expect = 0.068
Identities = 52/203 (25%), Positives = 79/203 (38%), Gaps = 21/203 (10%)
Query: 2571 KAFSEARSVISEKRTLSRNSTR-KPVFS-TFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
K F E S I ++ + + T K + + T L D AV +K+ I S WY
Sbjct: 9564 KEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLS-----WY 9618
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
+ L+ K+ + TL V N D Y G SA L V
Sbjct: 9619 KGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTV----- 9669
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
I P + R ++D + C+ P K WF++ + + GR++ +
Sbjct: 9670 ---IEPAWERHLQDVTLKEGQTCTMTCQF-SVPNVKSEWFRNGRILKPQGRHKT-EVEHK 9724
Query: 2749 VCRLAIDNPTPEDSGTYTCKAEN 2771
V +L I + ED G YTCK E+
Sbjct: 9725 VHKLTIADVRAEDQGQYTCKYED 9747
Score = 41.1 bits (92), Expect = 0.068
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 26/254 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL EY+FRV N+ G G + +T + I DRP GE NL
Sbjct: 18990 NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRP--------------GEPENLH 19035
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEE--AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
+ KGK + W + ++ + + + G D + +I E Y +
Sbjct: 19036 IADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK-ETHYMVDRCVE 19094
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD-RRVQATYPVRLT 3188
+ Y V T E+D +K E E P ++L V+A +RL
Sbjct: 19095 N---QIY-EFRVQTKNEGGESDW-VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLE 19149
Query: 3189 CQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL--DDGGVYEVTARNNS 3246
V G P P+V+W KD + + D + + + + T DGG Y VTA N +
Sbjct: 19150 AGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTA 19209
Query: 3247 GAVSCHCGL-VVDK 3259
G+ + + V+DK
Sbjct: 19210 GSFVAYATVNVLDK 19223
Score = 41.1 bits (92), Expect = 0.068
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P V + + + W + + V+ Y +E WV+L TP+ F
Sbjct: 23271 PGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLER---KERNSILWVKLNKTPIPQTKF 23327
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTS 3038
L++G EY FRV+ N G G+ S+ S
Sbjct: 23328 KTTGLEEGVEYEFRVSAENIVGIGKPSKVS 23357
Score = 40.7 bits (91), Expect = 0.090
Identities = 25/91 (27%), Positives = 37/91 (40%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP L++ V V L C + G P P V+WY++ ++ L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G + +A N +G VS C L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 40.7 bits (91), Expect = 0.090
Identities = 57/251 (22%), Positives = 92/251 (36%), Gaps = 27/251 (10%)
Query: 2714 ECRIR--GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
ECR+ G P + W D K + + R + G C L DSG TC+A N
Sbjct: 1723 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATN 1781
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG---NVLTD------- 2821
TD + + +S V + + + + R R H G V TD
Sbjct: 1782 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1841
Query: 2822 --------YQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+V G T + + G P +V W G+ + + R RV + G++ L +
Sbjct: 1842 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR-FRVRYD-GIHYLDI 1899
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
D ++G A + G ++ + + Q D +V+ PE V E
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF---RSVLRRAPEPRPEFHVHEPGK 1956
Query: 2933 ISFRTQGEPKP 2943
+ F Q +P
Sbjct: 1957 LQFEVQKVDRP 1967
Score = 40.7 bits (91), Expect = 0.090
Identities = 46/185 (24%), Positives = 76/185 (41%), Gaps = 20/185 (10%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLN 2655
T L D +EG++ L C V +V WY N + D+++ + +V G V+N
Sbjct: 2449 TPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVIN 2505
Query: 2656 AV-PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
SD Y V G + T+ NL V E I R +RD +V E
Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSV----EKIKI----IRGLRDLTCTETQNVVFE 2553
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
+ + + W DK+I +Y+ + +L + N +D G YT A ++
Sbjct: 2554 VELSHSGI-DVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEGKYTFYAGENIT 2611
Query: 2775 TDQIT 2779
+ ++T
Sbjct: 2612 SGKLT 2616
Score = 40.7 bits (91), Expect = 0.090
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTI 3111
FV L ++ ++ G+ L+C + + VVW K+G V E+ GR+ G LTI
Sbjct: 12141 FVKTLEEEVTVVKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGRIVPGVIGLMRALTI 12198
Query: 3112 KDINIDDEGRYSCEATNTH 3130
D + D G Y+ N +
Sbjct: 12199 NDADDTDAGTYTVTVENAN 12217
Score = 40.7 bits (91), Expect = 0.090
Identities = 73/320 (22%), Positives = 125/320 (39%), Gaps = 35/320 (10%)
Query: 2940 EPKPKAVPERIPGE---PCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR 2996
EP P PG P + + + ++++W +P+ Y +E A
Sbjct: 20404 EPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQA---VN 20460
Query: 2997 WVELGITPL--NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVD 3054
W ++ P+ + A L++G EY FRVT N+ G G+ S S + A D P++
Sbjct: 20461 WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKA---AYARD-PQYPP 20516
Query: 3055 ILPGQLKILAGETANLTCSVKGKPV-----PGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P K+ ++++ S GKP P + ++ + + R N
Sbjct: 20517 APPAFPKVYDTTRSSVSLS-WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 20575
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
+ + D + ++ A N G Y+ + V D+ + D + E E++ D
Sbjct: 20576 FEVTGLMEDTQYQFRVYAVNKIG----YSDPSDVPDKH-YPKDILIPPE--GELDADLRK 20628
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEI 3227
+R A +RL V G PPPK++W K + D+ + F T L
Sbjct: 20629 TLILR-------AGVTMRLYVPVKGRPPPKITWSKPNVN-LRDRIGLDIKSTDFDTFLRC 20680
Query: 3228 APTNLDDGGVYEVTARNNSG 3247
N D G Y +T N+ G
Sbjct: 20681 ENVNKYDAGKYILTLENSCG 20700
Score = 40.7 bits (91), Expect = 0.090
Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 4/102 (3%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A VLE IRG+P+P + W KD K++ L + + D G Y
Sbjct: 25648 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 25707
Query: 2767 CKAENSVWTDQITHFVNFTGR----ESQVSPNVVTAEKTRIA 2804
K N T I V R E + VTAEK +A
Sbjct: 25708 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLA 25749
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G L++ + P VT RDGV L+ + R + + + + L T DAG Y
Sbjct: 27418 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAEN-LTINLKESVTADAGRYEI 27476
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVIS 3375
TA+N G +T + ++ D+ P PVVIS
Sbjct: 27477 TAANSSG--TTKAFINIVVLDRPGPP-TGPVVIS 27507
Score = 40.3 bits (90), Expect = 0.12
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 21/187 (11%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L + T E T + + V W +NGV+L++ KY + + +L + N
Sbjct: 2713 LKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIV 2772
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D + Y + G + SA L V E I + +D L + E +
Sbjct: 2773 DESVYGFRL----GRLGASARLHV----ETVKI----IKKPKDVTALENATVAFEVSVSH 2820
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT-------CKAENS 2772
+P + WF + +I +++ V +L + N +P D+G YT CKA+
Sbjct: 2821 DTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLF 2878
Query: 2773 VWTDQIT 2779
V T IT
Sbjct: 2879 VETLHIT 2885
Score = 40.3 bits (90), Expect = 0.12
Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 15/173 (8%)
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
L+D V A C++ P V WY G+++ + + + HTL + L+
Sbjct: 13129 LKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 13187
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA 3293
D G ++TA++ H L V + EF LE + EG + V +
Sbjct: 13188 DAGEVQLTAKD----FKTHANLFVKE-----PPVEFTKPLED-QTVEEGATAVLECEV-S 13236
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASN 3345
+ V W+++G + S++ + DG++ +L + T D YTC A +
Sbjct: 13237 RENAKVKWFKNGTEILKSKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKD 13287
Score = 40.3 bits (90), Expect = 0.12
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 3167 PPQFTMRLRDRR---VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ + R+ V+A P+RL V G P PKV+W K G + V K + D
Sbjct: 19530 PPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF 19589
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSG 3247
L I + DD G Y +T N +G
Sbjct: 19590 -LVIPNSTRDDSGKYSLTLVNPAG 19612
Score = 40.3 bits (90), Expect = 0.12
Identities = 73/313 (23%), Positives = 117/313 (37%), Gaps = 34/313 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V + + + W D + ++ Y VE + G RW++ L
Sbjct: 22581 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER---RDKAGQRWIKCNKKTLT 22637
Query: 3007 S--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
+ L +G EY FR+ N G S TS +P PG ++L
Sbjct: 22638 DLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG----PPGNPRVL- 22692
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVE-----EEAGRMTSQFNGFDCC-LTIKDINID 3117
+T+ + S+ KP+ G+ VE E+ ++ + G TI + +
Sbjct: 22693 -DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTEN 22751
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
E + A N+ G + T D L E E++ D T+R
Sbjct: 22752 QEYKIRIYAMNSEGLGEP-----ALVPGTPKAEDRMLPPE--IELDADLRKVVTIR---- 22800
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
A +RL + G P P+V W +D E + DK + + L + N D G
Sbjct: 22801 ---ACCTLRLFVPIKGRPAPEVKWARDHGESL-DKASIE-STSSYTLLIVGNVNRFDSGK 22855
Query: 3238 YEVTARNNSGAVS 3250
Y +T N+SG+ S
Sbjct: 22856 YILTVENSSGSKS 22868
Score = 39.9 bits (89), Expect = 0.16
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 17/169 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E +L C ++S + WY N V L + KY G L V +
Sbjct: 2273 LQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKE 2331
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIR 2718
D EYS ++ + T+ LK+ P P + + D + E ++V LE ++
Sbjct: 2332 DQGEYSFVIDGK----KTTCKLKM------KPRPIAILQGLSDQ-KVCEGDIVQLEVKVS 2380
Query: 2719 GQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
+ + + W KD +++ PSD + + L I++ T ED+G Y+
Sbjct: 2381 LESVEGV-WMKDGQEVQPSDRVH--IVIDKQSHMLLIEDMTKEDAGNYS 2426
Score = 39.9 bits (89), Expect = 0.16
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 11/169 (6%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN-NSGAVSCHCGLVV 3257
++W G + ++ NK E+ L+ +L +GG YE + N+ VS V
Sbjct: 16978 LAWDPTGTKKEAWRQCNKRDVEE---LQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVG 17034
Query: 3258 DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIM- 3316
+ P L+ ++ EG + I A ++ P +TW++ + ++ ++
Sbjct: 17035 PCDCQRPDMPP-SIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY 17093
Query: 3317 -----TLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
L D L + D G+YT TA N +G AS ++ V+G
Sbjct: 17094 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 17142
Score = 39.9 bits (89), Expect = 0.16
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +RI A V+ P +TW ++G L +R + D ++EL + D G Y
Sbjct: 18850 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLP-RVELQIKEAVRADHGKYII 18908
Query: 3342 TASNEVGRASTSGKVEVI 3359
+A N G A S V V+
Sbjct: 18909 SAKNSSGHAQGSAIVNVL 18926
Score = 39.9 bits (89), Expect = 0.16
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 2701 RDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+DT L E LE + G+P P + W KD K++ + + +AD L + T
Sbjct: 22395 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE-IKIADFSTNLVNKDSTR 22453
Query: 2760 EDSGTYTCKAEN 2771
DSG YT A N
Sbjct: 22454 RDSGAYTLTATN 22465
Score = 39.9 bits (89), Expect = 0.16
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
L G+ R+ A V P + W +DG L + + + + D L T RD+G
Sbjct: 22400 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGA 22458
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVV 3373
YT TA+N G A V+V+ D+ P P V
Sbjct: 22459 YTLTATNPGGFAKHIFNVKVL--DRPGPPEGPLAV 22491
Score = 39.9 bits (89), Expect = 0.16
Identities = 23/79 (29%), Positives = 38/79 (48%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A +++ + G P PKV+ +DG + R N + T+ + + D G Y
Sbjct: 27415 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 27474
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
E+TA N+SG +VV
Sbjct: 27475 EITAANSSGTTKAFINIVV 27493
Score = 39.5 bits (88), Expect = 0.21
Identities = 15/38 (39%), Positives = 23/38 (60%)
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+P+F+ KP S + EG T + +VVG P P+ +W D
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1493
Score = 39.5 bits (88), Expect = 0.21
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 9/141 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E V C V ++ W+RN + + KY D + TL + +A
Sbjct: 13573 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 13631
Query: 2660 DSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D A Y+ ++ N G + ++ANL V E + ++D + + + C++
Sbjct: 13632 DQANYNVSLTNHRGENVKSAANLIV----EEEDL--RIVEPLKDIETMEKKSVTFWCKVN 13685
Query: 2719 GQPLPKITWFKDDKQIPSDGR 2739
+ + W K+ +++P D R
Sbjct: 13686 RLNV-TLKWTKNGEEVPFDNR 13705
Score = 39.5 bits (88), Expect = 0.21
Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 7/121 (5%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL 2634
E+R VI +++T+ + ++ + A G +K+ V+ PTVTW + +L
Sbjct: 21977 ESRPVIVKEQTMLPELDLRGIYQKLVI---AKAGDNIKVEIPVLGRPKPTVTWKKGDQIL 22033
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
+ + L + V SDS Y T N G + ++V+ P PP
Sbjct: 22034 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHD----IPGPP 22089
Query: 2695 T 2695
T
Sbjct: 22090 T 22090
Score = 39.5 bits (88), Expect = 0.21
Identities = 22/76 (28%), Positives = 32/76 (42%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G K+ + PT+ W + L N + K D +L V +AV DS Y
Sbjct: 23485 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 23544
Query: 2668 VENENGAISTSANLKV 2683
+N G S + N+KV
Sbjct: 23545 AKNVAGERSVTVNVKV 23560
Score = 39.5 bits (88), Expect = 0.21
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
Y + G++L+I V P ++W +DG L+ + R + + L + D
Sbjct: 25248 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LHIKEGNKDDF 25306
Query: 3337 GVYTCTASNEVGRASTSGKVEVI 3359
G YT TA+N G A+ + V V+
Sbjct: 25307 GKYTVTATNSAGTATENLSVIVL 25329
Score = 39.1 bits (87), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+F ++D +V C+V P V W KD +E+ R +++ H L I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIP 3117
Query: 3229 PTNLDDGGVYEVTARNN 3245
T + D G Y V A N
Sbjct: 3118 STRMSDAGKYTVVAGGN 3134
Score = 39.1 bits (87), Expect = 0.28
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L ++ G A +V G+P P V W K ++
Sbjct: 3621 PHFLKELK-PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 3679
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
+ D +D G Y C+A N G+++ A L V+ + T D K + + E D+P
Sbjct: 3680 IVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM-TDTPCKAKSTPEAPEDFP 3736
Score = 39.1 bits (87), Expect = 0.28
Identities = 75/325 (23%), Positives = 124/325 (38%), Gaps = 36/325 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--- 3007
PG+P V+ + ++W +P+ Y +E EG W + P+
Sbjct: 16529 PGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEK---REEGSPYWSRVSRAPITKVGL 16585
Query: 3008 ----FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL 3063
F+ L +G +Y FR N G G S+ S +AGD P F P ++
Sbjct: 16586 KGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP---EVAGD-PIFPPGPPSCPEVK 16641
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
++++ K G +K G+ VE + T K +N D+ +
Sbjct: 16642 DKTKSSISLGWKPPAKDGGSPIK-GYIVEMQEEGTTDW----------KRVNEPDKLITT 16690
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEAD-AKLKRERSAEVEGDYPPQFT-MRLRDRRV-Q 3180
CE + K R V E++ + E A + P F + +D V +
Sbjct: 16691 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCK 16750
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDG--EEVVYDKRRNKYQDEQFHTLE------IAPTNL 3232
A +R+ + G P PK SW DG ++ + D + +D Q T E I
Sbjct: 16751 AGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKR 16810
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVV 3257
G Y +TA+N +G + +C + V
Sbjct: 16811 SHTGKYSITAKNKAGQKTANCRVKV 16835
Score = 39.1 bits (87), Expect = 0.28
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 3167 PPQFTMRLRDRRV---QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ M ++ R V +A +++ + G P P +SW KDG E+ R +
Sbjct: 26713 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 26772
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSG--AVSCHCGLVVDK 3259
L + D G Y +T +N +G +V+ +C V+DK
Sbjct: 26773 LLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNC-KVLDK 26809
Score = 38.7 bits (86), Expect = 0.36
Identities = 65/299 (21%), Positives = 109/299 (36%), Gaps = 40/299 (13%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDC 3107
+P FV+ L + I G + G P P +VW+KN V + ++ + +
Sbjct: 1555 KPMFVEKLKN-VNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1613
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL----KRERSAEV- 3162
L I D Y+ A N G+ +T ++ V + E + KL R+ E+
Sbjct: 1614 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1673
Query: 3163 -----------------EGD-------YPPQFTMRLRDRRVQATYPVRLTCQV--IGSPP 3196
EGD P F +L R++ P C++ IG P
Sbjct: 1674 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPT 1733
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
V W DG+ + R + + +L+ D G+ A N G L+
Sbjct: 1734 MVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Query: 3257 V--DKG-IRAYVAPEFCCGLEPLYKL----HEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
V +K + PE GL+ + +L HEG ++ + + Y + VR+
Sbjct: 1794 VKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1852
Score = 38.7 bits (86), Expect = 0.36
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRV 3023
V L W D +P+ Y VE + + + ++ +T L F +L QG+EY F+V
Sbjct: 14431 VHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDF-VTDLE-FTVPDLVQGKEYLFKV 14488
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPE 3051
RN+ G GE + + + P+
Sbjct: 14489 CARNKCGPGEPAYVDEPVNMSTPATVPD 14516
Score = 38.3 bits (85), Expect = 0.48
Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 11/178 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE--VTARNNSGAV- 3249
G P K + EE D +R D+ T E NL + Y V A N +G
Sbjct: 16659 GGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESE 16718
Query: 3250 -SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
S G + I+ G + G ++RI AV++ P+ +W DG
Sbjct: 16719 PSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAK 16778
Query: 3309 RPSRRAIMTLDRDGQIELA-------LAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ + + + D Q+E A + G Y+ TA N+ G+ + + +V+V+
Sbjct: 16779 KAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVM 16836
Score = 38.3 bits (85), Expect = 0.48
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 11/125 (8%)
Query: 2947 PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P +P EP V + + +AW + D +P++ Y +E WV+ T
Sbjct: 20015 PFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER---KERNSLLWVKANDT 20071
Query: 3004 PLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGD---RPEFVDILPG 3058
+ S + L +G EY FR+ N+ G S+ + + + D +PE +D+
Sbjct: 20072 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKS 20131
Query: 3059 QLKIL 3063
+ ++
Sbjct: 20132 TVSLI 20136
Score = 38.3 bits (85), Expect = 0.48
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 7/133 (5%)
Query: 2659 SDSAEYSCTV--ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAE--NELVLE 2714
++ EY+ V ENENG T + + V + P + + D +LA+ + L+
Sbjct: 20873 TEGKEYTFRVSAENENGE-GTPSEITVVARDDVVA-PDLDLKGLPDLCYLAKENSNFRLK 20930
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
I+G+P P ++W K + + +D R A + D D+G YT +N
Sbjct: 20931 IPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYD-CQKSDAGKYTITLKNVAG 20989
Query: 2775 TDQITHFVNFTGR 2787
T + T + G+
Sbjct: 20990 TKEGTISIKVVGK 21002
Score = 38.3 bits (85), Expect = 0.48
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 8/145 (5%)
Query: 2663 EYSCTVENENGAIST-SANLKVYPSFEASPIPP-TFTRSIRDTFHLAENELV-LECRIRG 2719
E+ +N GAIS S + + + +P + RDT + E LE + G
Sbjct: 24519 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 24578
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
+PLP I W + DK+I R + D L + + D G Y +A N +
Sbjct: 24579 KPLPTIEWLRGDKEIEESARCE-IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFP 24637
Query: 2780 HFVNFTGR----ESQVSPNVVTAEK 2800
V R E V VT+EK
Sbjct: 24638 VNVKVLDRPGPPEGPVQVTGVTSEK 24662
Score = 37.9 bits (84), Expect = 0.64
Identities = 42/166 (25%), Positives = 76/166 (45%), Gaps = 20/166 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV---DGLIT 2650
P F+ L D T VE V L C IS +D V W+++G ++K K V DG
Sbjct: 12945 PYFTGKLQDYTGVEKDEVILQCE-ISKADAPVKWFKDG----KEIKPSKNAVIKADGKKR 12999
Query: 2651 LEVL-NAVPSDSAEYSCT--VENENGAIS-TSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
+ +L A+ SD +Y+C + +G + +K+ + + T T R +
Sbjct: 13000 MLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETET--ARFETEI 13057
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
+E+++ +++G+ L + D +I +G+ + L + CRL
Sbjct: 13058 SEDDIHANWKLKGEALLQ----TPDCEIKEEGKIHSLVLHN--CRL 13097
Score = 37.9 bits (84), Expect = 0.64
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 3278 KLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDR----DGQIELALAAVT 3332
K+ G+ + I A V P + W ++ + +P+ +T + + + EL++
Sbjct: 16336 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 16395
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
D G YT TASN +G + VEV D+ S PR
Sbjct: 16396 REDKGTYTVTASNRLGSVFRNVHVEVY--DRPSPPR 16429
Score = 37.9 bits (84), Expect = 0.64
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
R++ ++ +RL+ + G P PKV+W K+ + R + LEI +D
Sbjct: 18153 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARID--VTPVGSKLEIRNAAHED 18210
Query: 3235 GGVYEVTARNNSGAVSCHCG-LVVDK 3259
GG+Y +T N +G+ + LV+DK
Sbjct: 18211 GGIYSLTVENPAGSKTVSVKVLVLDK 18236
Score = 37.9 bits (84), Expect = 0.64
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G ++L V P VTW + G+ DN + K + LVD + L + N+ DS +YS
Sbjct: 19548 GCPIRLFAIVRGRPAPKVTWRKVGI--DNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSL 19605
Query: 2667 TVENENGAISTSANLKV 2683
T+ N G + N++V
Sbjct: 19606 TLVNPAGEKAVFVNVRV 19622
Score = 37.9 bits (84), Expect = 0.64
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 7/97 (7%)
Query: 2677 TSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS 2736
T L + P + S IP + T + N + LE +G+P P I+W KD +
Sbjct: 28480 TVKELIITPEVDLSDIP-----GAQVTVRIGHN-VHLELPYKGKPKPSISWLKDGLPL-K 28532
Query: 2737 DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ + F + L+I N E G YT +N+V
Sbjct: 28533 ESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV 28569
Score = 37.5 bits (83), Expect = 0.84
Identities = 39/193 (20%), Positives = 77/193 (39%), Gaps = 3/193 (1%)
Query: 1268 VRNMSVSKEDEFFTEAIEMETITEQKQTDQTNELVKENIQETSQTDSKDLDVTIEKFGNE 1327
V +V +E F E + ++ + + +E + + + + V E+ E
Sbjct: 10384 VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREE-ERE 10442
Query: 1328 EEQKAKPTDEEIQNEDGHYLVKENKKQNKADTEIGKVEKQNKQEVDFV-KDQIEMELNEK 1386
EE++A+ T+ E+ E Y+V+E E E +QE V K +I ++ E
Sbjct: 10443 EEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEP 10502
Query: 1387 NASAIEEKTETTILPVKLEQEQVDERELANKEEENRKLEVSTARKKAEADSKKIQEEQGN 1446
+ + E + I+P K V ++E + + + KK K++E
Sbjct: 10503 PPAKVPEAPK-KIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPA 10561
Query: 1447 KSNEENSYTAKEK 1459
K E + +E+
Sbjct: 10562 KVTERHMQITQEE 10574
Score = 37.5 bits (83), Expect = 0.84
Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ L+I+A + P ++W +DG+ + R + + D L + RD G Y
Sbjct: 26731 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIRRDTGQYVL 26789
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T N G S + +V+ D+ P P
Sbjct: 26790 TLKNVAGTRSVAVNCKVL--DKPGPPAGP 26816
Score = 37.1 bits (82), Expect = 1.1
Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
P+F L DY + LQ EI V+W ++G+ + + +NA + + L L
Sbjct: 12945 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEI-KPSKNAVIKADGKKRMLIL 13003
Query: 2873 SDVTETESGLYTCRAWS--AHGNVDM-NAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
+++ G YTC + G +D+ + I +V+P R E +I +
Sbjct: 13004 KKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEI---SED 13060
Query: 2930 DINISFRTQGE 2940
DI+ +++ +GE
Sbjct: 13061 DIHANWKLKGE 13071
Score = 37.1 bits (82), Expect = 1.1
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW--VELGITPLNSF 3008
PG P V + ++++W + +P+L Y VE G W V + P N F
Sbjct: 22189 PGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVER---KERNGILWQTVSKALVPGNIF 22245
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTS 3038
+ L G Y FRV N G + S+ S
Sbjct: 22246 KSSGLTDGIAYEFRVIAENMAGKSKPSKPS 22275
Score = 36.7 bits (81), Expect = 1.5
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVF 2862
IA L P + L D + G T + + + EW R GR + R+ +
Sbjct: 9662 IASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRH-KTE 9720
Query: 2863 VEQGLYTLALSDVTETESGLYTCR 2886
VE ++ L ++DV + G YTC+
Sbjct: 9721 VEHKVHKLTIADVRAEDQGQYTCK 9744
Score = 36.7 bits (81), Expect = 1.5
Identities = 23/79 (29%), Positives = 32/79 (40%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A VR + G P P W DG E+ D+ D L I D G Y
Sbjct: 18449 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 18508
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
++T N +G+ + L V
Sbjct: 18509 QITVSNAAGSKTVAVHLTV 18527
Score = 36.7 bits (81), Expect = 1.5
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 3167 PPQFTMRLRDRRV---QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ + R+V +A+ +RL + G P P+V W K E ++ D+ + + F
Sbjct: 26031 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEV-TSSFT 26088
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGA 3248
L I D G Y +T NNSG+
Sbjct: 26089 MLVIDNVTRFDSGRYNLTLENNSGS 26113
Score = 36.7 bits (81), Expect = 1.5
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 7/125 (5%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A L L I+G+P P++ W K + + + + + L IDN T DSG Y
Sbjct: 26048 ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIE---VTSSFTMLVIDNVTRFDSGRYN 26104
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHF--GNVLTDYQV 2824
EN+ + T FVN +S +P +T + + +L P G +T+Y V
Sbjct: 26105 LTLENN--SGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIV 26162
Query: 2825 ARGGT 2829
+ T
Sbjct: 26163 EKRET 26167
Score = 36.3 bits (80), Expect = 1.9
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 3049 RPEFVDILPG--QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
+P + IL G K+ G+ L V + V GV WMK+G EV + + R+ +
Sbjct: 2352 KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEV-QPSDRVHIVIDKQS 2409
Query: 3107 CCLTIKDINIDDEGRYS----CEATNTHGKASTYA 3137
L I+D+ +D G YS +T G+ S Y+
Sbjct: 2410 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS 2444
Score = 36.3 bits (80), Expect = 1.9
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 14/181 (7%)
Query: 1282 EAIEMETITEQKQTDQTNELVKENIQETSQTDSKDLDVTIEKFGNE-EEQKAKPTDEEIQ 1340
E +++ TIT +K+ + KE + E Q K+ V IE F +E + +P E +
Sbjct: 9962 EEVKIMTITRKKEVQKE----KEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFE 10017
Query: 1341 NEDGHYLVKENKKQNKADTEIGKVEKQNKQEVDFVKDQIEMELNEKNASAIEEKTETTIL 1400
Y + ++ + E K E + E DF + Q E E EE E
Sbjct: 10018 QP---YYEEPDEDYEEIKVE-AKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAY-- 10071
Query: 1401 PVKLEQEQVDERELANKEEENRKLEVSTARKKAEADSKKIQEEQGNKSNEENSYTAKEKT 1460
E+E + ++ +E RK+ KKA K I++ K + + +EK
Sbjct: 10072 ---QEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKV 10128
Query: 1461 K 1461
+
Sbjct: 10129 Q 10129
Score = 36.3 bits (80), Expect = 1.9
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EFV+ L Q + + A +C + + V W +NG E++E + + +G L
Sbjct: 13751 EFVEHLEDQT-VTEFDDAVFSCQLSREKA-NVKWYRNGREIKE-GKKYKFEKDGSIHRLI 13807
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTY 3136
IKD +DDE Y+C + +A +
Sbjct: 13808 IKDCRLDDECEYACGVEDRKSRARLF 13833
Score = 36.3 bits (80), Expect = 1.9
Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
R++G+P P ITW K+ K + + R V L I D G Y A+NS
Sbjct: 18858 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADHGKYIISAKNSSGH 18916
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Q + VN R VT S E+ + G+ +T++ V
Sbjct: 18917 AQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 18965
Score = 36.3 bits (80), Expect = 1.9
Identities = 46/162 (28%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 2653 VLNAVPSDSAEYSCTVENENGAIS----TSANLKVYPSFEASPIPPTFTRSIRDTFHL-A 2707
V + V E+ +N GAIS ++ + +EA I +I+D + A
Sbjct: 21262 VTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTI--VLDPTIKDGLTIKA 21319
Query: 2708 ENELVLEC-RIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ +VL I G+PLPK +W K K I PSD L I T +D+G Y
Sbjct: 21320 GDTIVLNAISILGKPLPKSSWSKAGKDIRPSD--ITQITSTPTSSMLTIKYATRKDAGEY 21377
Query: 2766 TCKAENSVWTDQITH----FVNFTGRESQVSPNVVTAEKTRI 2803
T A N T ++ H ++ G V + V+AEK +
Sbjct: 21378 TITATNPFGT-KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 21418
Score = 36.3 bits (80), Expect = 1.9
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVV-YDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
RL V G PPP + W KDG+E+ K K D + + T D G Y +TA N
Sbjct: 22407 RLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDSGAYTLTATN 22465
Query: 3245 NSG 3247
G
Sbjct: 22466 PGG 22468
Score = 36.3 bits (80), Expect = 1.9
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A +L +E + G+P P I+W KD + + R A L I +D G YT
Sbjct: 25252 AGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LHIKEGNKDDFGKYT 25310
Query: 2767 CKAENSVWT 2775
A NS T
Sbjct: 25311 VTATNSAGT 25319
Score = 36.3 bits (80), Expect = 1.9
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 9/123 (7%)
Query: 2662 AEYSCTVENEN--GAI--STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
AEY V++ N GA S S++ ++ E P+ + + A +
Sbjct: 27078 AEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPF 27137
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFY-LADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
RG+P+P + W K D +D R +A+ D L I+N DSG YT +N +
Sbjct: 27138 RGRPVPNVLWSKPD----TDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 27193
Query: 2777 QIT 2779
+T
Sbjct: 27194 SLT 27196
Score = 36.3 bits (80), Expect = 1.9
Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
D P ++T ++ R A V+L + G P P + WYKD +E+ + +
Sbjct: 27800 DLPLEYTEVVKYR---AGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 27856
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVS 3250
+ I + + G YE+ RN G+ S
Sbjct: 27857 ILIKDADRLNSGCYELKLRNAMGSAS 27882
Score = 36.3 bits (80), Expect = 1.9
Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 8/113 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+P +T ++ + A + L I G+P P I W+KDDK++ ++ D +
Sbjct: 27801 LPLEYTEVVK---YRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LAS 27856
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVVTAEK 2800
+ I + +SG Y K N++ + T V + + VTAEK
Sbjct: 27857 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEK 27909
Score = 35.9 bits (79), Expect = 2.6
Identities = 37/168 (22%), Positives = 59/168 (35%), Gaps = 3/168 (1%)
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTF--TRSIRDTFHLAENELVLECRIRGQP 2721
Y N GA S + + + P F + + A ++ L + G+P
Sbjct: 14586 YRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 14645
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKITW K D + D R + +D+ D+GTY +A N
Sbjct: 14646 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR-SDTGTYIIEAVNVCGRATAVVE 14704
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
VN + + +T + R G+ +T+Y V R T
Sbjct: 14705 VNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRAT 14752
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/76 (27%), Positives = 31/76 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L V PT+ W ++G L+ K K+ D L ++ DS Y+ T
Sbjct: 22403 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 22462
Query: 2668 VENENGAISTSANLKV 2683
N G N+KV
Sbjct: 22463 ATNPGGFAKHIFNVKV 22478
Score = 35.9 bits (79), Expect = 2.6
Identities = 24/102 (23%), Positives = 38/102 (37%), Gaps = 4/102 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F T + G +K+ I P VTW+++ V L + + + L +
Sbjct: 23075 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 23134
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT 2695
+A D Y + N G + N+ V P PPT
Sbjct: 23135 KDACREDVGHYVVKLTNSAGEAIETLNVIVLD----KPGPPT 23172
Score = 35.5 bits (78), Expect = 3.4
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERS 3159
+G D KD I +Y EA HGK L ++ D + + A + +
Sbjct: 2559 SGIDVLWNFKDKEIKPSSKYKIEA---HGKIYKLTVLNMMKDDEGKYTFYAGENITSGKL 2615
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
G + L D+ V + C+V +P K W +DG+ + D
Sbjct: 2616 TVAGG----AISKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESD 2670
Query: 3220 EQFHTLEIAPTNLDDGGVY 3238
L IA T LDD G Y
Sbjct: 2671 GHKRRLIIAATKLDDIGEY 2689
Score = 35.5 bits (78), Expect = 3.4
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
+AN K + + +P F + D ++E EC + +P W K ++I D
Sbjct: 12751 AANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGD 12809
Query: 2738 GRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAEN 2771
R++ + DG + I + ED Y +AE+
Sbjct: 12810 DRFE--LIKDGTKHSMVIKSAAFEDEAKYMFEAED 12842
Score = 35.5 bits (78), Expect = 3.4
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPI--PPTFTRSIRDTFHLAENELVLECRI 2717
+ EY V EN A + + P+ PI P R+ + +E+ L+ I
Sbjct: 15573 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKR--GDEIALDASI 15630
Query: 2718 RGQPLPKITWFKDDKQI 2734
G P P ITW KD+ I
Sbjct: 15631 SGSPYPTITWIKDENVI 15647
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+RG+P PK+TW K I + R L D + L I N T +DSG Y+ N
Sbjct: 19557 VRGRPAPKVTWRK--VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVN 19609
Score = 35.5 bits (78), Expect = 3.4
Identities = 30/126 (23%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 3238 YEVTARNNSGAVSCHCGLVVD-KGIRAYVAPEFCCGLE--PLYKLHEGDELRISAVVEAY 3294
+ V ARN G++S +V I +Y P LE + K G +++ A +
Sbjct: 27767 FRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 27826
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASNEVGRASTS 3353
P+ + WY+D L+ + A++ ++ + L R ++G Y N +G AS +
Sbjct: 27827 PAPTIEWYKDDKELQTN--ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT 27884
Query: 3354 GKVEVI 3359
+V+++
Sbjct: 27885 IRVQIL 27890
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
T R+P V P P P + ++ EG++V +EC + G P P V W R+
Sbjct: 927 TETARVPAPVEIPVTP----PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRE 979
Score = 35.1 bits (77), Expect = 4.5
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 8/106 (7%)
Query: 2950 IPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
+PG P + D VSL W + A + Y +E + + RW
Sbjct: 14117 VPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIE---LRDKTSIRWDTAMTVRAE 14173
Query: 3007 SFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP 3050
A ++ +G+EY FRV +NR G G+ S + + V +RP
Sbjct: 14174 DLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 14219
Score = 35.1 bits (77), Expect = 4.5
Identities = 21/69 (30%), Positives = 30/69 (43%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A + L V G P PK++W K + DKR + T+ I + D G Y
Sbjct: 14629 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 14688
Query: 3239 EVTARNNSG 3247
+ A N G
Sbjct: 14689 IIEAVNVCG 14697
Score = 35.1 bits (77), Expect = 4.5
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 2997 WVELGIT-PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
W ++ T P+ S L +G EY FR+ N+YG G+ T +I
Sbjct: 20362 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAI 20407
Score = 35.1 bits (77), Expect = 4.5
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A L L I+G+P P++ W K D +I + L +DN DSG YT
Sbjct: 23883 AGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID---VTSSFTSLVLDNVNRYDSGKYT 23939
Query: 2767 CKAENSVWT 2775
ENS T
Sbjct: 23940 LTLENSSGT 23948
Score = 35.1 bits (77), Expect = 4.5
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KP FS++ + G +K+ + PT+TW ++G+ L + L TL
Sbjct: 24160 KPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLS 24215
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL 2681
+ D +Y TV N G + S +
Sbjct: 24216 IKETHKDDGGQYGITVANVVGQKTASIEI 24244
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/55 (32%), Positives = 25/55 (45%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
G PPP V+W KD + + D R + + L I +D G Y +T N G
Sbjct: 28224 GRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 28278
Score = 34.7 bits (76), Expect = 5.9
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 7/135 (5%)
Query: 3230 TNLDDGG--VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL--HEGDEL 3285
T L++G Y V A N GA + + APE ++ L L G ++
Sbjct: 14576 TGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 14635
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTAS 3344
+ A V P +TW + + L+ +R +T++ + + R D G Y A
Sbjct: 14636 ELPATVTGKPEPKITWTKADMILKQDKR--ITIENVPKKSTVTIVDSKRSDTGTYIIEAV 14693
Query: 3345 NEVGRASTSGKVEVI 3359
N GRA+ +V V+
Sbjct: 14694 NVCGRATAVVEVNVL 14708
Score = 34.7 bits (76), Expect = 5.9
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYT 3340
G LRI AVV P W ++ L R + +D G + EL + +D G Y
Sbjct: 16046 GKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKDHGRYV 16102
Query: 3341 CTASNEVGRASTSGKVEV 3358
TA+N G + +VEV
Sbjct: 16103 ITATNSCGSKFAAARVEV 16120
Score = 34.7 bits (76), Expect = 5.9
Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 2951 PGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN- 3006
PG P V D L+W + APV Y +E + WV +
Sbjct: 27205 PGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKA---WVSVTNNCNRL 27261
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE 3051
S+ NL++G Y+FRV+ N +G G ++T + + PE
Sbjct: 27262 SYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 27306
Score = 34.7 bits (76), Expect = 5.9
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +++ V P VTW+++GV ++ ++ V G +L V +A Y T
Sbjct: 28900 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY--T 28957
Query: 2668 VENENGAISTSANLKV 2683
VE +N + S A +KV
Sbjct: 28958 VEAKNASGSAKAEIKV 28973
Score = 34.7 bits (76), Expect = 5.9
Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 4/131 (3%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + ++ I G+P PK+TW ++ ++ R D L + + DSG Y
Sbjct: 29588 AGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRT-TLTVKDSMRGDSGRYF 29646
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVS-PNVVTAEKTRIARQSLESRRPHFGNVLTDYQVA 2825
EN+ + V GR V+ P V++ S + G +T+Y V
Sbjct: 29647 LTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVE 29706
Query: 2826 R--GGTIGLQV 2834
+ GT Q+
Sbjct: 29707 KRESGTTAWQL 29717
Score = 34.7 bits (76), Expect = 5.9
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G I + P+ VTW + +RL+ + R +T +D + L + D+G Y
Sbjct: 29589 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKD-RTTLTVKDSMRGDSGRYFL 29647
Query: 3342 TASNEVGRASTSGKVEVIG 3360
T N G + S V VIG
Sbjct: 29648 TLENTAGVKTFSVTVVVIG 29666
Score = 34.3 bits (75), Expect = 7.9
Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 15/85 (17%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVE-------SWLIGAEGGARWVELGITPLNSFDAFNLKQG 3016
VSLAW + + ++ Y VE +W++ + A E +T L K G
Sbjct: 14033 VSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDR-AESCEFTVTGLQ-------KGG 14084
Query: 3017 EEYHFRVTPRNRYGWGESSQTSSSI 3041
EY FRV+ RNR G GE +T + +
Sbjct: 14085 VEYLFRVSARNRVGTGEPVETDNPV 14109
Score = 34.3 bits (75), Expect = 7.9
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 3/81 (3%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV-CRL 2752
PT D + +L + R P+P ++W KD K++ + R D + L
Sbjct: 15314 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT--MKNDHISAHL 15371
Query: 2753 AIDNPTPEDSGTYTCKAENSV 2773
+ D+G YT EN +
Sbjct: 15372 EVPKSVRADAGIYTITLENKL 15392
Score = 34.3 bits (75), Expect = 7.9
Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+G+P P+ITW +++ + + + +L+IDN D+G Y K ENS
Sbjct: 24976 KGRPTPEITWSREEGEFTDKVQIEK---GVNYTQLSIDNCDRNDAGKYILKLENS 25027
>BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein.
Length = 510
Score = 111 bits (268), Expect = 3e-23
Identities = 95/317 (29%), Positives = 132/317 (41%), Gaps = 21/317 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN-GFDCCLTIKDINIDDE 3119
KI G TC V G P P + W K+G ++ ++ T Q + C L +DD+
Sbjct: 138 KIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD 197
Query: 3120 GRYSCEATNTHGKASTYARLAV--VTDR----TVWEADAKLKRERSAEVE-GD------- 3165
G Y+ A N G+ S RL V V R ++R RS + GD
Sbjct: 198 GNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQE 257
Query: 3166 --YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-F 3222
+ P F D VQ R+ C+V G P P +SW DG+ V D E
Sbjct: 258 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 317
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
H+L I P D G+Y A N +G S LVV A+ P F L+ + +G
Sbjct: 318 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-AAKEAHKPPVFIEKLQNT-GVADG 375
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+R+ V P + W ++ L S R M D G I L + T DAG YT
Sbjct: 376 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 435
Query: 3342 TASNEVGRASTSGKVEV 3358
+A NE G S + +++V
Sbjct: 436 SAKNEAGIVSCTARLDV 452
Score = 101 bits (242), Expect = 5e-20
Identities = 70/212 (33%), Positives = 100/212 (47%), Gaps = 23/212 (10%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDC 3107
RP F+ PG L + G+ + C V G P P + W +G V + A +M + NG
Sbjct: 261 RPHFLQA-PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH- 318
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C ATN G+ S L V A E P
Sbjct: 319 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV------------------AAKEAHKP 360
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P F +L++ V YPVRL C+V+G PPP++ W K+ E + + R + +QD + L
Sbjct: 361 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 420
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G Y V+A+N +G VSC L V
Sbjct: 421 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 452
Score = 84.2 bits (199), Expect = 7e-15
Identities = 71/247 (28%), Positives = 107/247 (43%), Gaps = 21/247 (8%)
Query: 2715 CRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN-- 2771
CR+ G P PKI WFKD KQI P Y DG C L T +D G YT A N
Sbjct: 149 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 208
Query: 2772 ---SVWTDQITHFVNFTGRESQVSPN---VVTAEKTRI-----ARQSLESR--RPHFGNV 2818
S + VN GR S SP+ V ++R + ++ R RPHF
Sbjct: 209 GRISCTGRLMVQAVNQRGR-SPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA 267
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
D V G + ++ G PT + W +G+ V + + E G+++L + VT
Sbjct: 268 PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 327
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRT 2937
++G+YTC A + G + + V KP V + + + + ++ G + + R
Sbjct: 328 RDAGIYTCIATNRAGQNSFSLELVVAAKE--AHKPPVFIEKLQ-NTGVADGYPVRLECRV 384
Query: 2938 QGEPKPK 2944
G P P+
Sbjct: 385 LGVPPPQ 391
Score = 72.1 bits (169), Expect = 3e-11
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 17/142 (11%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG R+ V P+ ++W DG +RP M + +G L + VT+RDAG+
Sbjct: 273 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 332
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
YTC A+N G+ S S ++ V+ + +P P+FI K +++ +G
Sbjct: 333 YTCIATNRAGQNSFSLEL-VVAAKEAHKP----------------PVFIEKLQNTGVADG 375
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P ++W ++
Sbjct: 376 YPVRLECRVLGVPPPQIFWKKE 397
Score = 66.9 bits (156), Expect = 1e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 4/181 (2%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F D T EG ++ C V P ++W +G + ++ + + +
Sbjct: 261 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 320
Query: 2653 VLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ V S D+ Y+C N G S S L V + EA PP F +++T +
Sbjct: 321 IIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK-PPVFIEKLQNTGVADGYPV 378
Query: 2712 VLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
LECR+ G P P+I W K+++ + S R G L I T ED+G YT A+
Sbjct: 379 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 438
Query: 2771 N 2771
N
Sbjct: 439 N 439
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/390 (23%), Positives = 143/390 (36%), Gaps = 64/390 (16%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR--KKLVDGLITL 2651
P F L EG V TC V + P + W+++G + K + ++ +DG +L
Sbjct: 128 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 187
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP------------------ 2693
+ D Y+ N G IS + L V + P
Sbjct: 188 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 247
Query: 2694 ------PTFTRSIRDTFHLAENELVLE----CR----IRGQPLPKITWFKDDKQIPSDGR 2739
P R R F A +L ++ CR + G P P ++W D K + D
Sbjct: 248 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 307
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAE 2799
++ +GV L I+ T D+G YTC A N G+ S VV A+
Sbjct: 308 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR------------AGQNSFSLELVVAAK 355
Query: 2800 KTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
+ + P F L + VA G + L+ + G P ++ W +E S+T +
Sbjct: 356 EAH--------KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLT--HST 405
Query: 2859 ARVFVEQ---GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV----QPSDLDGK 2911
RV + Q G L + T+ ++G YT A + G V A + V Q S
Sbjct: 406 DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP 465
Query: 2912 PAVIVGRPEKDILISVGEDINISFRTQGEP 2941
V L G DI +F+ + P
Sbjct: 466 KKVRPSASRYAALSDQGLDIKAAFQPEANP 495
Score = 65.3 bits (152), Expect = 4e-09
Identities = 52/167 (31%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRP-SRRAIMTLDRDGQIELALAAVTTRD 3335
YK+ EG + + V P + W++DG ++ P S + D DG L A T D
Sbjct: 137 YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 196
Query: 3336 AGVYTCTASNEVGRASTSGKVEVIGTDQTS-EPRIP---PVVISP-----DVPYSKEPM- 3385
G YT A+N GR S +G++ V +Q PR P P V P D EP+
Sbjct: 197 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 256
Query: 3386 -------FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
F++ P +EG ++C+V G P PD+ W D VR
Sbjct: 257 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 303
Score = 64.9 bits (151), Expect = 5e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
VE P F M+L+ ++ PV TC+V G+P PK+ W+KDG+++ Q +
Sbjct: 122 VENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDL 181
Query: 3222 FHT--LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
T L + LDD G Y + A N G +SC L+V
Sbjct: 182 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 219
Score = 47.2 bits (107), Expect = 0.001
Identities = 84/360 (23%), Positives = 130/360 (36%), Gaps = 32/360 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVE-QGLYTL 2870
P F L Y++ G + + G P ++ W ++G+ ++ + + + G +L
Sbjct: 128 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 187
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVG-----RPEKDILI 2925
+ T + G YT A + G + + V + P G RP
Sbjct: 188 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 247
Query: 2926 SVGEDINIS---FRTQGEPKPKAVPERIPGEPCVVD---GGNNWVSLAWPKSDPQTTAPV 2979
S E+ I FR P + + G+ C +D G L+W + D + P
Sbjct: 248 SGDENEPIQERFFRPHFLQAPGDLTVQ-EGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPD 305
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
A+K ++ E G L I P+ S DA + NR G S
Sbjct: 306 SAHK----MLVRENGVH--SLIIEPVTSRDAGI--------YTCIATNRAGQNSFS-LEL 350
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+ A P F++ L + G L C V G P P + W K + R++
Sbjct: 351 VVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVS 409
Query: 3100 S-QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRER 3158
Q N CL I+ +D G Y+ A N G S ARL V T K K+ R
Sbjct: 410 MHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVR 469
Score = 44.8 bits (101), Expect = 0.006
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
++ + + PVF L + +G V+L C V+ P + W + L + D
Sbjct: 354 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 413
Query: 2647 --GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
G I L + A D+ Y+ + +NE G +S +A L VY
Sbjct: 414 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 453
Score = 38.3 bits (85), Expect = 0.48
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
DVP P F K + + EG V C V G+PKP +YW +D
Sbjct: 119 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKD 164
>AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein.
Length = 1106
Score = 111 bits (268), Expect = 3e-23
Identities = 95/317 (29%), Positives = 132/317 (41%), Gaps = 21/317 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN-GFDCCLTIKDINIDDE 3119
KI G TC V G P P + W K+G ++ ++ T Q + C L +DD+
Sbjct: 787 KIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD 846
Query: 3120 GRYSCEATNTHGKASTYARLAV--VTDR----TVWEADAKLKRERSAEVE-GD------- 3165
G Y+ A N G+ S RL V V R ++R RS + GD
Sbjct: 847 GNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQE 906
Query: 3166 --YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-F 3222
+ P F D VQ R+ C+V G P P +SW DG+ V D E
Sbjct: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 966
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
H+L I P D G+Y A N +G S LVV A+ P F L+ + +G
Sbjct: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-AAKEAHKPPVFIEKLQNT-GVADG 1024
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+R+ V P + W ++ L S R M D G I L + T DAG YT
Sbjct: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
Query: 3342 TASNEVGRASTSGKVEV 3358
+A NE G S + +++V
Sbjct: 1085 SAKNEAGIVSCTARLDV 1101
Score = 101 bits (242), Expect = 5e-20
Identities = 70/212 (33%), Positives = 100/212 (47%), Gaps = 23/212 (10%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDC 3107
RP F+ PG L + G+ + C V G P P + W +G V + A +M + NG
Sbjct: 910 RPHFLQA-PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH- 967
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C ATN G+ S L V A E P
Sbjct: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV------------------AAKEAHKP 1009
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P F +L++ V YPVRL C+V+G PPP++ W K+ E + + R + +QD + L
Sbjct: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G Y V+A+N +G VSC L V
Sbjct: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
Score = 84.2 bits (199), Expect = 7e-15
Identities = 71/247 (28%), Positives = 107/247 (43%), Gaps = 21/247 (8%)
Query: 2715 CRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN-- 2771
CR+ G P PKI WFKD KQI P Y DG C L T +D G YT A N
Sbjct: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
Query: 2772 ---SVWTDQITHFVNFTGRESQVSPN---VVTAEKTRI-----ARQSLESR--RPHFGNV 2818
S + VN GR S SP+ V ++R + ++ R RPHF
Sbjct: 858 GRISCTGRLMVQAVNQRGR-SPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA 916
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
D V G + ++ G PT + W +G+ V + + E G+++L + VT
Sbjct: 917 PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRT 2937
++G+YTC A + G + + V KP V + + + + ++ G + + R
Sbjct: 977 RDAGIYTCIATNRAGQNSFSLELVVAAKE--AHKPPVFIEKLQ-NTGVADGYPVRLECRV 1033
Query: 2938 QGEPKPK 2944
G P P+
Sbjct: 1034 LGVPPPQ 1040
Score = 72.1 bits (169), Expect = 3e-11
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 17/142 (11%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG R+ V P+ ++W DG +RP M + +G L + VT+RDAG+
Sbjct: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
YTC A+N G+ S S ++ V+ + +P P+FI K +++ +G
Sbjct: 982 YTCIATNRAGQNSFSLEL-VVAAKEAHKP----------------PVFIEKLQNTGVADG 1024
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P ++W ++
Sbjct: 1025 YPVRLECRVLGVPPPQIFWKKE 1046
Score = 66.9 bits (156), Expect = 1e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 4/181 (2%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F D T EG ++ C V P ++W +G + ++ + + +
Sbjct: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
Query: 2653 VLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ V S D+ Y+C N G S S L V + EA PP F +++T +
Sbjct: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK-PPVFIEKLQNTGVADGYPV 1027
Query: 2712 VLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
LECR+ G P P+I W K+++ + S R G L I T ED+G YT A+
Sbjct: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
Query: 2771 N 2771
N
Sbjct: 1088 N 1088
Score = 65.7 bits (153), Expect = 3e-09
Identities = 84/347 (24%), Positives = 131/347 (37%), Gaps = 60/347 (17%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR--KKLVDGLITL 2651
P F L EG V TC V + P + W+++G + K + ++ +DG +L
Sbjct: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP------------------ 2693
+ D Y+ N G IS + L V + P
Sbjct: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
Query: 2694 ------PTFTRSIRDTFHLAENELVLE----CR----IRGQPLPKITWFKDDKQIPSDGR 2739
P R R F A +L ++ CR + G P P ++W D K + D
Sbjct: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAE 2799
++ +GV L I+ T D+G YTC A N G+ S VV A+
Sbjct: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR------------AGQNSFSLELVVAAK 1004
Query: 2800 KTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
+ + P F L + VA G + L+ + G P ++ W +E S+T +
Sbjct: 1005 EAH--------KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLT--HST 1054
Query: 2859 ARVFVEQ---GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
RV + Q G L + T+ ++G YT A + G V A + V
Sbjct: 1055 DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
Score = 65.3 bits (152), Expect = 4e-09
Identities = 52/167 (31%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRP-SRRAIMTLDRDGQIELALAAVTTRD 3335
YK+ EG + + V P + W++DG ++ P S + D DG L A T D
Sbjct: 786 YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845
Query: 3336 AGVYTCTASNEVGRASTSGKVEVIGTDQTS-EPRIP---PVVISP-----DVPYSKEPM- 3385
G YT A+N GR S +G++ V +Q PR P P V P D EP+
Sbjct: 846 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 905
Query: 3386 -------FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
F++ P +EG ++C+V G P PD+ W D VR
Sbjct: 906 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
Score = 64.9 bits (151), Expect = 5e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
VE P F M+L+ ++ PV TC+V G+P PK+ W+KDG+++ Q +
Sbjct: 771 VENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDL 830
Query: 3222 FHT--LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
T L + LDD G Y + A N G +SC L+V
Sbjct: 831 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
Score = 60.5 bits (140), Expect = 1e-07
Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 8/100 (8%)
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEE--------VVYDKRRNKY 3217
+PP FT L++ V V L C+V G+PP +V W++ G E ++ K R+
Sbjct: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ E+ TL IA T +D G++ +ARN+ G+ + LVV
Sbjct: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 57.2 bits (132), Expect = 1e-06
Identities = 42/154 (27%), Positives = 69/154 (44%), Gaps = 6/154 (3%)
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS---PIPPTFTRSIRDTFHLAE 2708
E+ V S A + C +N++ A+ N K +P ++ P P F + +R
Sbjct: 229 EMEREVKSPGARH-CYQDNQDLAVPH--NRKSHPQPHSALHFPAAPRFIQKLRSQEVAEG 285
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ + LECR+ G P P++ WF + K++ + Q + L I +D+G YTC
Sbjct: 286 SRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCL 345
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
A N +D + V G S S + A K+R
Sbjct: 346 ATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSR 379
Score = 56.4 bits (130), Expect = 2e-06
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYL------- 2745
PP FT+ +++T +VLECR+RG P ++ WF+ +I ++
Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ +C L I PED+G +TC A N
Sbjct: 500 PEEICTLVIAETFPEDAGIFTCSARN 525
Score = 50.4 bits (115), Expect = 1e-04
Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDEQFHTLE 3226
P+F +LR + V V L C+V G+P P+V W+ +G+E+ + + HTL
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 3227 IAPTNLDDGGVYEVTARNNSGA 3248
IA DD G Y A N SG+
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGS 352
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQG-LYTL 2870
P F L +VA G + L+ + G PT RV W EG+ + + ++ E G L+TL
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT-PDIQIHCEGGDLHTL 329
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLD 2909
+++ E ++G YTC A + G+ +A + + S D
Sbjct: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD 368
Score = 49.2 bits (112), Expect = 3e-04
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG-LITLE 2652
P F L + EGSRV L C V + P V W+ G L N + G L TL
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL 2681
+ A D+ Y+C N +G+ +TSA +
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEV 359
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L Q ++ G L C V G P P V W G E+ G L
Sbjct: 271 PRFIQKLRSQ-EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
I + DD GRY+C ATN G +T A + +
Sbjct: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
Score = 46.0 bits (104), Expect = 0.002
Identities = 81/347 (23%), Positives = 126/347 (36%), Gaps = 32/347 (9%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVE-QGLYTL 2870
P F L Y++ G + + G P ++ W ++G+ ++ + + + G +L
Sbjct: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVG-----RPEKDILI 2925
+ T + G YT A + G + + V + P G RP
Sbjct: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
Query: 2926 SVGEDINIS---FRTQGEPKPKAVPERIPGEPCVVD---GGNNWVSLAWPKSDPQTTAPV 2979
S E+ I FR P + + G+ C +D G L+W + D + P
Sbjct: 897 SGDENEPIQERFFRPHFLQAPGDLTVQ-EGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPD 954
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
A+K ++ E G L I P+ S DA + NR G S
Sbjct: 955 SAHK----MLVRENGVH--SLIIEPVTSRDAGI--------YTCIATNRAGQNSFS-LEL 999
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+ A P F++ L + G L C V G P P + W K + R++
Sbjct: 1000 VVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVS 1058
Query: 3100 S-QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDR 3145
Q N CL I+ +D G Y+ A N G S ARL V R
Sbjct: 1059 MHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISR 1105
Score = 45.2 bits (102), Expect = 0.004
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
++ + + PVF L + +G V+L C V+ P + W + L + D
Sbjct: 1003 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 1062
Query: 2647 --GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
G I L + A D+ Y+ + +NE G +S +A L VY S
Sbjct: 1063 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
Score = 43.6 bits (98), Expect = 0.013
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 9/93 (9%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG--------RMTSQFNGFDCCLTIKD 3113
+ G+ L C V+G P V W + G E+++ R T++ C L I +
Sbjct: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI-CTLVIAE 510
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRT 3146
+D G ++C A N +G A++ A+L V + T
Sbjct: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
Score = 42.7 bits (96), Expect = 0.022
Identities = 18/34 (52%), Positives = 21/34 (61%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P FI+K RS E EG V +EC V G+P P V W
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRW 304
Score = 42.3 bits (95), Expect = 0.030
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTE------VYRNARVFVE- 2864
P F L + VA G + L+ +RG P +V+W R+G + + + + R E
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ + TL +++ ++G++TC A + +G+ A + V
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 41.9 bits (94), Expect = 0.039
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR---KK-----LV 2645
PVF+ L + EG V L C V + V W+R G + + +R KK
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + TL + P D+ ++C+ N+ G+ +++A L V
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 41.5 bits (93), Expect = 0.052
Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 8/103 (7%)
Query: 3263 AYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS-------RRAI 3315
AY P F L+ + EG + + V P + V W+R G ++ S ++
Sbjct: 437 AYFPPVFTKELQNT-AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPR 495
Query: 3316 MTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
T + + L +A DAG++TC+A N+ G A+++ ++ V
Sbjct: 496 STAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 39.1 bits (87), Expect = 0.28
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP F L ++ EG + + V P+ V W+ +G L + + +
Sbjct: 270 APRFIQKLRS-QEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQT 3364
L +A D G YTC A+N G +TS +V + G T
Sbjct: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASST 367
Score = 38.3 bits (85), Expect = 0.48
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
DVP P F K + + EG V C V G+PKP +YW +D
Sbjct: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKD 813
Score = 34.3 bits (75), Expect = 7.9
Identities = 13/36 (36%), Positives = 21/36 (58%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
P+F ++ +++ EG V++EC V G P V W R
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFR 476
>AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein.
Length = 404
Score = 111 bits (268), Expect = 3e-23
Identities = 95/317 (29%), Positives = 132/317 (41%), Gaps = 21/317 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN-GFDCCLTIKDINIDDE 3119
KI G TC V G P P + W K+G ++ ++ T Q + C L +DD+
Sbjct: 32 KIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD 91
Query: 3120 GRYSCEATNTHGKASTYARLAV--VTDR----TVWEADAKLKRERSAEVE-GD------- 3165
G Y+ A N G+ S RL V V R ++R RS + GD
Sbjct: 92 GNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQE 151
Query: 3166 --YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-F 3222
+ P F D VQ R+ C+V G P P +SW DG+ V D E
Sbjct: 152 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 211
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
H+L I P D G+Y A N +G S LVV A+ P F L+ + +G
Sbjct: 212 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-AAKEAHKPPVFIEKLQNT-GVADG 269
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+R+ V P + W ++ L S R M D G I L + T DAG YT
Sbjct: 270 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 329
Query: 3342 TASNEVGRASTSGKVEV 3358
+A NE G S + +++V
Sbjct: 330 SAKNEAGIVSCTARLDV 346
Score = 101 bits (242), Expect = 5e-20
Identities = 70/212 (33%), Positives = 100/212 (47%), Gaps = 23/212 (10%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDC 3107
RP F+ PG L + G+ + C V G P P + W +G V + A +M + NG
Sbjct: 155 RPHFLQA-PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH- 212
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C ATN G+ S L V A E P
Sbjct: 213 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV------------------AAKEAHKP 254
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P F +L++ V YPVRL C+V+G PPP++ W K+ E + + R + +QD + L
Sbjct: 255 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 314
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G Y V+A+N +G VSC L V
Sbjct: 315 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 346
Score = 84.2 bits (199), Expect = 7e-15
Identities = 71/247 (28%), Positives = 107/247 (43%), Gaps = 21/247 (8%)
Query: 2715 CRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN-- 2771
CR+ G P PKI WFKD KQI P Y DG C L T +D G YT A N
Sbjct: 43 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 102
Query: 2772 ---SVWTDQITHFVNFTGRESQVSPN---VVTAEKTRI-----ARQSLESR--RPHFGNV 2818
S + VN GR S SP+ V ++R + ++ R RPHF
Sbjct: 103 GRISCTGRLMVQAVNQRGR-SPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA 161
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
D V G + ++ G PT + W +G+ V + + E G+++L + VT
Sbjct: 162 PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 221
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRT 2937
++G+YTC A + G + + V KP V + + + + ++ G + + R
Sbjct: 222 RDAGIYTCIATNRAGQNSFSLELVVAAKE--AHKPPVFIEKLQ-NTGVADGYPVRLECRV 278
Query: 2938 QGEPKPK 2944
G P P+
Sbjct: 279 LGVPPPQ 285
Score = 72.1 bits (169), Expect = 3e-11
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 17/142 (11%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG R+ V P+ ++W DG +RP M + +G L + VT+RDAG+
Sbjct: 167 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 226
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
YTC A+N G+ S S ++ V+ + +P P+FI K +++ +G
Sbjct: 227 YTCIATNRAGQNSFSLEL-VVAAKEAHKP----------------PVFIEKLQNTGVADG 269
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P ++W ++
Sbjct: 270 YPVRLECRVLGVPPPQIFWKKE 291
Score = 66.9 bits (156), Expect = 1e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 4/181 (2%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F D T EG ++ C V P ++W +G + ++ + + +
Sbjct: 155 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 214
Query: 2653 VLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ V S D+ Y+C N G S S L V + EA PP F +++T +
Sbjct: 215 IIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK-PPVFIEKLQNTGVADGYPV 272
Query: 2712 VLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
LECR+ G P P+I W K+++ + S R G L I T ED+G YT A+
Sbjct: 273 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 332
Query: 2771 N 2771
N
Sbjct: 333 N 333
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/390 (23%), Positives = 143/390 (36%), Gaps = 64/390 (16%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR--KKLVDGLITL 2651
P F L EG V TC V + P + W+++G + K + ++ +DG +L
Sbjct: 22 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 81
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP------------------ 2693
+ D Y+ N G IS + L V + P
Sbjct: 82 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 141
Query: 2694 ------PTFTRSIRDTFHLAENELVLE----CR----IRGQPLPKITWFKDDKQIPSDGR 2739
P R R F A +L ++ CR + G P P ++W D K + D
Sbjct: 142 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 201
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAE 2799
++ +GV L I+ T D+G YTC A N G+ S VV A+
Sbjct: 202 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR------------AGQNSFSLELVVAAK 249
Query: 2800 KTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
+ + P F L + VA G + L+ + G P ++ W +E S+T +
Sbjct: 250 EAH--------KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLT--HST 299
Query: 2859 ARVFVEQ---GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV----QPSDLDGK 2911
RV + Q G L + T+ ++G YT A + G V A + V Q S
Sbjct: 300 DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP 359
Query: 2912 PAVIVGRPEKDILISVGEDINISFRTQGEP 2941
V L G DI +F+ + P
Sbjct: 360 KKVRPSASRYAALSDQGLDIKAAFQPEANP 389
Score = 65.3 bits (152), Expect = 4e-09
Identities = 52/167 (31%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRP-SRRAIMTLDRDGQIELALAAVTTRD 3335
YK+ EG + + V P + W++DG ++ P S + D DG L A T D
Sbjct: 31 YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 90
Query: 3336 AGVYTCTASNEVGRASTSGKVEVIGTDQTS-EPRIP---PVVISP-----DVPYSKEPM- 3385
G YT A+N GR S +G++ V +Q PR P P V P D EP+
Sbjct: 91 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 150
Query: 3386 -------FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
F++ P +EG ++C+V G P PD+ W D VR
Sbjct: 151 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 197
Score = 62.9 bits (146), Expect = 2e-08
Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D + + +A + P F M+L+ ++ PV TC+V G+P PK+ W+KDG+++
Sbjct: 5 DERSRTADAASWKTGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP 64
Query: 3211 DKRRNKYQDEQFHT--LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
Q + T L + LDD G Y + A N G +SC L+V
Sbjct: 65 KSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 113
Score = 47.2 bits (107), Expect = 0.001
Identities = 84/360 (23%), Positives = 130/360 (36%), Gaps = 32/360 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVE-QGLYTL 2870
P F L Y++ G + + G P ++ W ++G+ ++ + + + G +L
Sbjct: 22 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 81
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVG-----RPEKDILI 2925
+ T + G YT A + G + + V + P G RP
Sbjct: 82 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 141
Query: 2926 SVGEDINIS---FRTQGEPKPKAVPERIPGEPCVVD---GGNNWVSLAWPKSDPQTTAPV 2979
S E+ I FR P + + G+ C +D G L+W + D + P
Sbjct: 142 SGDENEPIQERFFRPHFLQAPGDLTVQ-EGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPD 199
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
A+K ++ E G L I P+ S DA + NR G S
Sbjct: 200 SAHK----MLVRENGVH--SLIIEPVTSRDAGI--------YTCIATNRAGQNSFS-LEL 244
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+ A P F++ L + G L C V G P P + W K + R++
Sbjct: 245 VVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVS 303
Query: 3100 S-QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRER 3158
Q N CL I+ +D G Y+ A N G S ARL V T K K+ R
Sbjct: 304 MHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVR 363
Score = 44.8 bits (101), Expect = 0.006
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
++ + + PVF L + +G V+L C V+ P + W + L + D
Sbjct: 248 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 307
Query: 2647 --GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
G I L + A D+ Y+ + +NE G +S +A L VY
Sbjct: 308 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 347
Score = 37.5 bits (83), Expect = 0.84
Identities = 15/37 (40%), Positives = 20/37 (54%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P F K + + EG V C V G+PKP +YW +D
Sbjct: 22 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKD 58
>AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein.
Length = 772
Score = 111 bits (268), Expect = 3e-23
Identities = 95/317 (29%), Positives = 132/317 (41%), Gaps = 21/317 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN-GFDCCLTIKDINIDDE 3119
KI G TC V G P P + W K+G ++ ++ T Q + C L +DD+
Sbjct: 400 KIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD 459
Query: 3120 GRYSCEATNTHGKASTYARLAV--VTDR----TVWEADAKLKRERSAEVE-GD------- 3165
G Y+ A N G+ S RL V V R ++R RS + GD
Sbjct: 460 GNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQE 519
Query: 3166 --YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-F 3222
+ P F D VQ R+ C+V G P P +SW DG+ V D E
Sbjct: 520 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 579
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
H+L I P D G+Y A N +G S LVV A+ P F L+ + +G
Sbjct: 580 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-AAKEAHKPPVFIEKLQNT-GVADG 637
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+R+ V P + W ++ L S R M D G I L + T DAG YT
Sbjct: 638 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 697
Query: 3342 TASNEVGRASTSGKVEV 3358
+A NE G S + +++V
Sbjct: 698 SAKNEAGIVSCTARLDV 714
Score = 101 bits (242), Expect = 5e-20
Identities = 70/212 (33%), Positives = 100/212 (47%), Gaps = 23/212 (10%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDC 3107
RP F+ PG L + G+ + C V G P P + W +G V + A +M + NG
Sbjct: 523 RPHFLQA-PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH- 580
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C ATN G+ S L V A E P
Sbjct: 581 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV------------------AAKEAHKP 622
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P F +L++ V YPVRL C+V+G PPP++ W K+ E + + R + +QD + L
Sbjct: 623 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 682
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G Y V+A+N +G VSC L V
Sbjct: 683 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 714
Score = 84.2 bits (199), Expect = 7e-15
Identities = 71/247 (28%), Positives = 107/247 (43%), Gaps = 21/247 (8%)
Query: 2715 CRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN-- 2771
CR+ G P PKI WFKD KQI P Y DG C L T +D G YT A N
Sbjct: 411 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 470
Query: 2772 ---SVWTDQITHFVNFTGRESQVSPN---VVTAEKTRI-----ARQSLESR--RPHFGNV 2818
S + VN GR S SP+ V ++R + ++ R RPHF
Sbjct: 471 GRISCTGRLMVQAVNQRGR-SPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA 529
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
D V G + ++ G PT + W +G+ V + + E G+++L + VT
Sbjct: 530 PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 589
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRT 2937
++G+YTC A + G + + V KP V + + + + ++ G + + R
Sbjct: 590 RDAGIYTCIATNRAGQNSFSLELVVAAKE--AHKPPVFIEKLQ-NTGVADGYPVRLECRV 646
Query: 2938 QGEPKPK 2944
G P P+
Sbjct: 647 LGVPPPQ 653
Score = 72.1 bits (169), Expect = 3e-11
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 17/142 (11%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG R+ V P+ ++W DG +RP M + +G L + VT+RDAG+
Sbjct: 535 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 594
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
YTC A+N G+ S S ++ V+ + +P P+FI K +++ +G
Sbjct: 595 YTCIATNRAGQNSFSLEL-VVAAKEAHKP----------------PVFIEKLQNTGVADG 637
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P ++W ++
Sbjct: 638 YPVRLECRVLGVPPPQIFWKKE 659
Score = 66.9 bits (156), Expect = 1e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 4/181 (2%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F D T EG ++ C V P ++W +G + ++ + + +
Sbjct: 523 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 582
Query: 2653 VLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ V S D+ Y+C N G S S L V + EA PP F +++T +
Sbjct: 583 IIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK-PPVFIEKLQNTGVADGYPV 640
Query: 2712 VLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
LECR+ G P P+I W K+++ + S R G L I T ED+G YT A+
Sbjct: 641 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 700
Query: 2771 N 2771
N
Sbjct: 701 N 701
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/390 (23%), Positives = 143/390 (36%), Gaps = 64/390 (16%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR--KKLVDGLITL 2651
P F L EG V TC V + P + W+++G + K + ++ +DG +L
Sbjct: 390 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 449
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP------------------ 2693
+ D Y+ N G IS + L V + P
Sbjct: 450 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 509
Query: 2694 ------PTFTRSIRDTFHLAENELVLE----CR----IRGQPLPKITWFKDDKQIPSDGR 2739
P R R F A +L ++ CR + G P P ++W D K + D
Sbjct: 510 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 569
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAE 2799
++ +GV L I+ T D+G YTC A N G+ S VV A+
Sbjct: 570 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR------------AGQNSFSLELVVAAK 617
Query: 2800 KTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
+ + P F L + VA G + L+ + G P ++ W +E S+T +
Sbjct: 618 EAH--------KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLT--HST 667
Query: 2859 ARVFVEQ---GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV----QPSDLDGK 2911
RV + Q G L + T+ ++G YT A + G V A + V Q S
Sbjct: 668 DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP 727
Query: 2912 PAVIVGRPEKDILISVGEDINISFRTQGEP 2941
V L G DI +F+ + P
Sbjct: 728 KKVRPSASRYAALSDQGLDIKAAFQPEANP 757
Score = 65.3 bits (152), Expect = 4e-09
Identities = 52/167 (31%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRP-SRRAIMTLDRDGQIELALAAVTTRD 3335
YK+ EG + + V P + W++DG ++ P S + D DG L A T D
Sbjct: 399 YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 458
Query: 3336 AGVYTCTASNEVGRASTSGKVEVIGTDQTS-EPRIP---PVVISP-----DVPYSKEPM- 3385
G YT A+N GR S +G++ V +Q PR P P V P D EP+
Sbjct: 459 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 518
Query: 3386 -------FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
F++ P +EG ++C+V G P PD+ W D VR
Sbjct: 519 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 565
Score = 64.9 bits (151), Expect = 5e-09
Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
VE P F M+L+ ++ PV TC+V G+P PK+ W+KDG+++ Q +
Sbjct: 384 VENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDL 443
Query: 3222 FHT--LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
T L + LDD G Y + A N G +SC L+V
Sbjct: 444 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 481
Score = 47.2 bits (107), Expect = 0.001
Identities = 84/360 (23%), Positives = 130/360 (36%), Gaps = 32/360 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVE-QGLYTL 2870
P F L Y++ G + + G P ++ W ++G+ ++ + + + G +L
Sbjct: 390 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 449
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVG-----RPEKDILI 2925
+ T + G YT A + G + + V + P G RP
Sbjct: 450 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 509
Query: 2926 SVGEDINIS---FRTQGEPKPKAVPERIPGEPCVVD---GGNNWVSLAWPKSDPQTTAPV 2979
S E+ I FR P + + G+ C +D G L+W + D + P
Sbjct: 510 SGDENEPIQERFFRPHFLQAPGDLTVQ-EGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPD 567
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
A+K ++ E G L I P+ S DA + NR G S
Sbjct: 568 SAHK----MLVRENGVH--SLIIEPVTSRDAGI--------YTCIATNRAGQNSFS-LEL 612
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+ A P F++ L + G L C V G P P + W K + R++
Sbjct: 613 VVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVS 671
Query: 3100 S-QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRER 3158
Q N CL I+ +D G Y+ A N G S ARL V T K K+ R
Sbjct: 672 MHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVR 731
Score = 44.8 bits (101), Expect = 0.006
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
++ + + PVF L + +G V+L C V+ P + W + L + D
Sbjct: 616 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 675
Query: 2647 --GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
G I L + A D+ Y+ + +NE G +S +A L VY
Sbjct: 676 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 715
Score = 38.3 bits (85), Expect = 0.48
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
DVP P F K + + EG V C V G+PKP +YW +D
Sbjct: 381 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKD 426
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 111 bits (266), Expect = 6e-23
Identities = 72/254 (28%), Positives = 123/254 (48%), Gaps = 17/254 (6%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+ P+F+ ++D + + VL+C +RG P+P+ITW + + I +Y GV
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 498
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L I + PED GTYTC AEN++ + +V ++S + + +
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL------LPVAPSKPT 552
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGL-YT 2869
P F L+D +V G + + V++ G P V WL G + E F ++G ++
Sbjct: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE--SEDFHFEQRGTQHS 610
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L + +V ++G YTC AW++ G V A +TV +P DG + +P + + S+G+
Sbjct: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKP-RSVTASLGQ 667
Query: 2930 DINISFRTQGEPKP 2943
+ IS G+P P
Sbjct: 668 SVLISCAIAGDPFP 681
Score = 102 bits (244), Expect = 3e-20
Identities = 92/329 (27%), Positives = 132/329 (40%), Gaps = 15/329 (4%)
Query: 3042 GVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQ 3101
G+ + P F +L ++ G+ L CSV+G PVP + W+ NG ++ R T +
Sbjct: 437 GLAVMEVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY--ARSTCE 493
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+ L I+D +D G Y+C A N G+ S A + TV E + K E
Sbjct: 494 AGVAE--LHIQDALPEDHGTYTCLAENALGQVSCSAWV------TVHEKKSSRKSEYLLP 545
Query: 3162 VEGDYP--PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
V P P F L D +V V +T QV G+PPP+V W +G E+ + + Q
Sbjct: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
H+L I +D G Y A N++G V L V + P F +
Sbjct: 606 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP-HDGTQPWFISKPRSV-TA 663
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + IS + P V W RDG L L + L L V AG Y
Sbjct: 664 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
N VG S + + + + PR
Sbjct: 724 EILLKNRVGECSCQVSLMLQNSSARALPR 752
Score = 97.9 bits (233), Expect = 6e-19
Identities = 80/266 (30%), Positives = 112/266 (42%), Gaps = 35/266 (13%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P F+ L+D V L C V G+P P+++W +G+ + Y + + + H +
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA 504
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD--KGIRA--YV---------APEFCCGLE 3274
P +D G Y A N G VSC + V K R Y+ AP F GL
Sbjct: 505 LP---EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
Query: 3275 PLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR 3334
L K+ +G ++ ++ V P V W +G ++ S R Q L + V
Sbjct: 562 DL-KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLCIQEVFPE 619
Query: 3335 DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE 3394
D G YTC A N G T + V EP +P FI KPRS
Sbjct: 620 DTGTYTCEAWNSAGEVRTQAVLTV------QEPHD-----------GTQPWFISKPRSVT 662
Query: 3395 AREGDTVIIECEVVGDPKPDVYWLRD 3420
A G +V+I C + GDP P V+WLRD
Sbjct: 663 ASLGQSVLISCAIAGDPFPTVHWLRD 688
Score = 91.9 bits (218), Expect = 4e-17
Identities = 74/304 (24%), Positives = 127/304 (41%), Gaps = 39/304 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLE 2652
P FS+ L D +EG L CSV + P +TW NG ++Y + + G+ L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEAGVAELH 500
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY------------PSFEASPIPPTFTRSI 2700
+ +A+P D Y+C EN G +S SA + V+ P + P P F + +
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
Query: 2701 RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D + +++ + ++ G P P++ W + +I + F L I PE
Sbjct: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLCIQEVFPE 619
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D+GTYTC+A NS V + ++ + +P F +
Sbjct: 620 DTGTYTCEAWNSA--------------------GEVRTQAVLTVQEPHDGTQPWFISKPR 659
Query: 2821 DYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
+ G ++ + I G P V WLR+G+++ + + V + ++TL L V
Sbjct: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
Query: 2880 SGLY 2883
+G Y
Sbjct: 720 AGQY 723
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/232 (27%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P F+ + P L I G TA V+G P P V W +NG + +
Sbjct: 31 EAPAFI-LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV-----------VTDRTVWEADAKLKR 3156
L I ++ +D G+Y+CEATN G L V V +T+ + +
Sbjct: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + G+ PP+F +L V+ R +C++ G P P+V+W K + R +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYV 3265
+ LEI N DD GVY N SG S L + D R++V
Sbjct: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 4/181 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F L+D ++GS+V +T V + P V W NG + + + +L +
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ Y+C N G + T A L V + + P F R +++
Sbjct: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ--PWFISKPRSVTASLGQSVLI 671
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C I G P P + W +D K + D G ++ D V L + P +G Y +N
Sbjct: 672 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNR 730
Query: 2773 V 2773
V
Sbjct: 731 V 731
Score = 70.1 bits (164), Expect = 1e-10
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 1080
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ PED G Y C A+N + + V T ++ S N E
Sbjct: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 1131
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 1132 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 1183
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W + V+ S+ K ++ R E +
Sbjct: 1184 ESVELFGKVTGTQP--ITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 1241 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 1300 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1356
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 1357 EKPEEPK 1363
Score = 69.7 bits (163), Expect = 2e-10
Identities = 55/199 (27%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E R+RG P P++TW ++ + I S GR+ G L I ED G YTC+A N
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
Query: 2774 WTDQITHFVNFTGR-ESQVSPNVVTAE-KTRIARQSLESR-------RPHFGNVLTDYQV 2824
Q+T + G Q+ VV+ R + ++E+R P F L V
Sbjct: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVV 172
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G +I G P +V WL+ G + V + G+ L + V + + G+Y
Sbjct: 173 KEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
Query: 2884 TCRAWSAHGNVDMNAAITV 2902
TC + G M+A +++
Sbjct: 232 TCLVVNGSGKASMSAELSI 250
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 1734 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1793
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 1794 GNCSLIISDVCGDDDAKYTCKAVNSL 1819
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 1749 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1808
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 1809 AKYTCKAVNSLGEATCTAELIVET 1832
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG + V YP VTW+R+G + R ++ G L + AV D G
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
Query: 3339 YTCTASNEVGRASTSGKVEVIGT--DQTSEPRI----------PPVVISPDVPYSKEPMF 3386
YTC A+N G + ++ V G+ Q +P + V P + P F
Sbjct: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKF 163
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
K +EG C++ G P+P V WL+
Sbjct: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Score = 59.3 bits (137), Expect = 2e-07
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI 3324
VAP F L+ + EG + + V P +TW +G +P + A T + G
Sbjct: 443 VAPSFSSVLKDCAVI-EGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEA-GVA 497
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG--TDQTSEPRIPPVVISPDVPYSK 3382
EL + D G YTC A N +G+ S S V V + + SE +P ++P P +
Sbjct: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP---VAPSKPTA- 553
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P+F++ + +G V + +V G+P P+V WL +
Sbjct: 554 -PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 1735 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1793
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 1794 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 54.4 bits (125), Expect = 7e-06
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG R S + P VTW + V L+PS R ++ +++G L + V D GVYT
Sbjct: 174 EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYT 232
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTS 3365
C N G+AS S ++ + G D +
Sbjct: 233 CLVVNGSGKASMSAELSIQGLDSAN 257
Score = 53.2 bits (122), Expect = 2e-05
Identities = 62/275 (22%), Positives = 104/275 (37%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 989 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 1047
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ +D G Y C A N
Sbjct: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALPEDRGLYKCVAKND 1106
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 1729 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1788
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 1789 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831
Score = 48.4 bits (110), Expect = 5e-04
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 1018 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1075
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+P D Y C +N+ G S + V P+ E + P +R
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 1739 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1798
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+T L EG + +C + P VTW + V L + +G+ LE+
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D Y+C V N +G S SA L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 1739 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1798
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1839
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 29/248 (11%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR 2629
S S+ + R S T P F + EG+ K V +P VTW+R
Sbjct: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
Query: 2630 NGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
NG + + ++ + G +L + D +Y+C N +GA + L V SF
Sbjct: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Query: 2689 ASPIPPTFTRSIRDTFHLAENE----LVLEC---------RI---RGQ-----------P 2721
P ++++ D F + E + EC R+ GQ P
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P++TW K + + R +G+ L I +D G YTC N ++
Sbjct: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
Query: 2782 VNFTGRES 2789
++ G +S
Sbjct: 248 LSIQGLDS 255
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 1028 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 1084
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1130
Score = 39.1 bits (87), Expect = 0.28
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1079
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1171
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 1731 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1781
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPD-VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
G V+++ + S+ + D +P ++ P FI PR+ +EG T E V G P+
Sbjct: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
Query: 3413 PDVYWLRD 3420
P V W R+
Sbjct: 62 PQVTWHRN 69
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 109 bits (263), Expect = 1e-22
Identities = 72/254 (28%), Positives = 123/254 (48%), Gaps = 17/254 (6%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+ P+F+ ++D + + VL+C +RG P+P+ITW + + I +Y GV
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 498
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L I + PED GTYTC AEN++ + +V ++S + + +
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL------LPVAPSKPT 552
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGL-YT 2869
P F L+D +V G + + V++ G P V WL G + E F ++G ++
Sbjct: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE--SEDFHFEQRGTQHS 610
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L + +V ++G YTC AW++ G V A +TV +P DG + +P + + S+G+
Sbjct: 611 LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKP-RSVTASLGQ 667
Query: 2930 DINISFRTQGEPKP 2943
+ IS G+P P
Sbjct: 668 SVLISCAIAGDPFP 681
Score = 102 bits (245), Expect = 2e-20
Identities = 92/329 (27%), Positives = 132/329 (40%), Gaps = 15/329 (4%)
Query: 3042 GVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQ 3101
G+ + P F +L ++ G+ L CSV+G PVP + W+ NG ++ R T +
Sbjct: 437 GLAVMEVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY--ARSTCE 493
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+ L I+D +D G Y+C A N G+ S A + TV E + K E
Sbjct: 494 AGVAE--LHIQDALPEDHGTYTCLAENALGQVSCSAWV------TVHEKKSSRKSEYLLP 545
Query: 3162 VEGDYP--PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
V P P F L D +V V +T QV G+PPP+V W +G E+ + + Q
Sbjct: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
H+L I +D G Y A N++G V L V + P F +
Sbjct: 606 GTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP-HDGTQPWFISKPRSV-TA 663
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + IS + P V W RDG L L + L L V AG Y
Sbjct: 664 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
N VG S + + + + PR
Sbjct: 724 EILLKNRVGECSCQVSLMLQNSSARALPR 752
Score = 96.7 bits (230), Expect = 1e-18
Identities = 80/266 (30%), Positives = 112/266 (42%), Gaps = 35/266 (13%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P F+ L+D V L C V G+P P+++W +G+ + Y + + + H +
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA 504
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD--KGIRA--YV---------APEFCCGLE 3274
P +D G Y A N G VSC + V K R Y+ AP F GL
Sbjct: 505 LP---EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
Query: 3275 PLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR 3334
L K+ +G ++ ++ V P V W +G ++ S R Q L + V
Sbjct: 562 DL-KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLWIQEVFPE 619
Query: 3335 DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE 3394
D G YTC A N G T + V EP +P FI KPRS
Sbjct: 620 DTGTYTCEAWNSAGEVRTQAVLTV------QEPHD-----------GTQPWFISKPRSVT 662
Query: 3395 AREGDTVIIECEVVGDPKPDVYWLRD 3420
A G +V+I C + GDP P V+WLRD
Sbjct: 663 ASLGQSVLISCAIAGDPFPTVHWLRD 688
Score = 90.6 bits (215), Expect = 9e-17
Identities = 74/304 (24%), Positives = 127/304 (41%), Gaps = 39/304 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLE 2652
P FS+ L D +EG L CSV + P +TW NG ++Y + + G+ L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEAGVAELH 500
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY------------PSFEASPIPPTFTRSI 2700
+ +A+P D Y+C EN G +S SA + V+ P + P P F + +
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
Query: 2701 RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D + +++ + ++ G P P++ W + +I + F L I PE
Sbjct: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLWIQEVFPE 619
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D+GTYTC+A NS V + ++ + +P F +
Sbjct: 620 DTGTYTCEAWNSA--------------------GEVRTQAVLTVQEPHDGTQPWFISKPR 659
Query: 2821 DYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
+ G ++ + I G P V WLR+G+++ + + V + ++TL L V
Sbjct: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
Query: 2880 SGLY 2883
+G Y
Sbjct: 720 AGQY 723
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/232 (27%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P F+ + P L I G TA V+G P P V W +NG + +
Sbjct: 31 EAPAFI-LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV-----------VTDRTVWEADAKLKR 3156
L I ++ +D G+Y+CEATN G L V V +T+ + +
Sbjct: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + G+ PP+F +L V+ R +C++ G P P+V+W K + R +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYV 3265
+ LEI N DD GVY N SG S L + D R++V
Sbjct: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261
Score = 71.7 bits (168), Expect = 4e-11
Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 4/181 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F L+D ++GS+V +T V + P V W NG + + + +L +
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 613
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ Y+C N G + T A L V + + P F R +++
Sbjct: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ--PWFISKPRSVTASLGQSVLI 671
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C I G P P + W +D K + D G ++ D V L + P +G Y +N
Sbjct: 672 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNR 730
Query: 2773 V 2773
V
Sbjct: 731 V 731
Score = 69.7 bits (163), Expect = 2e-10
Identities = 55/199 (27%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E R+RG P P++TW ++ + I S GR+ G L I ED G YTC+A N
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
Query: 2774 WTDQITHFVNFTGR-ESQVSPNVVTAE-KTRIARQSLESR-------RPHFGNVLTDYQV 2824
Q+T + G Q+ VV+ R + ++E+R P F L V
Sbjct: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVV 172
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G +I G P +V WL+ G + V + G+ L + V + + G+Y
Sbjct: 173 KEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
Query: 2884 TCRAWSAHGNVDMNAAITV 2902
TC + G M+A +++
Sbjct: 232 TCLVVNGSGKASMSAELSI 250
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 1682 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1741
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 1742 GNCSLIISDVCGDDDAKYTCKAVNSL 1767
Score = 66.5 bits (155), Expect = 2e-09
Identities = 84/367 (22%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 1080
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ ED G Y C A+N + + V T ++ S N E
Sbjct: 1081 GSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 1131
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 1132 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 1183
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W ++ V+ S+ K ++ R E +
Sbjct: 1184 ESVELFGKVTGTQP--ITC-TWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYT 1240
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 1241 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 1300 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1356
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 1357 EKPEEPK 1363
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG + V YP VTW+R+G + R ++ G L + AV D G
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
Query: 3339 YTCTASNEVGRASTSGKVEVIGT--DQTSEPRI----------PPVVISPDVPYSKEPMF 3386
YTC A+N G + ++ V G+ Q +P + V P + P F
Sbjct: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKF 163
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
K +EG C++ G P+P V WL+
Sbjct: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Score = 59.3 bits (137), Expect = 2e-07
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI 3324
VAP F L+ + EG + + V P +TW +G +P + A T + G
Sbjct: 443 VAPSFSSVLKDCAVI-EGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEA-GVA 497
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG--TDQTSEPRIPPVVISPDVPYSK 3382
EL + D G YTC A N +G+ S S V V + + SE +P ++P P +
Sbjct: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP---VAPSKPTA- 553
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P+F++ + +G V + +V G+P P+V WL +
Sbjct: 554 -PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
Score = 58.8 bits (136), Expect = 3e-07
Identities = 27/84 (32%), Positives = 43/84 (51%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 1697 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1756
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A V T
Sbjct: 1757 AKYTCKAVNSLGEATCTAEHIVET 1780
Score = 56.0 bits (129), Expect = 2e-06
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 1683 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1741
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
G L ++ V D YTC A N +G A+ + + ++ T + E
Sbjct: 1742 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE-HIVETMEEGE 1785
Score = 55.6 bits (128), Expect = 3e-06
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E+ +E +G P F +L+D V + L CQV PP + W +G+ + K
Sbjct: 1019 EKRSESQGT-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIIL 1077
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Q+ ++ I L+D G+Y+ A+N++G C C + VD
Sbjct: 1078 SQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVD 1119
Score = 54.4 bits (125), Expect = 7e-06
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG R S + P VTW + V L+PS R ++ +++G L + V D GVYT
Sbjct: 174 EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYT 232
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTS 3365
C N G+AS S ++ + G D +
Sbjct: 233 CLVVNGSGKASMSAELSIQGLDSAN 257
Score = 54.0 bits (124), Expect = 9e-06
Identities = 62/275 (22%), Positives = 105/275 (38%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 989 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 1047
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ ++D G Y C A N
Sbjct: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALLEDRGLYKCVAKND 1106
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENGSKL 1226
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+T L EG + +C + P VTW + V L + +G+ LE+
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D Y+C V N +G S SA L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 47.2 bits (107), Expect = 0.001
Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 1677 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1736
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C +V+
Sbjct: 1737 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1779
Score = 46.0 bits (104), Expect = 0.002
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 1687 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1746
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSA 2679
+ + D A+Y+C N G + +A
Sbjct: 1747 IISDVCGDDDAKYTCKAVNSLGEATCTA 1774
Score = 45.6 bits (103), Expect = 0.003
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 1687 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1746
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A V + +G+
Sbjct: 1747 IISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGE 1787
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 29/248 (11%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR 2629
S S+ + R S T P F + EG+ K V +P VTW+R
Sbjct: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
Query: 2630 NGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
NG + + ++ + G +L + D +Y+C N +GA + L V SF
Sbjct: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Query: 2689 ASPIPPTFTRSIRDTFHLAENE----LVLEC---------RI---RGQ-----------P 2721
P ++++ D F + E + EC R+ GQ P
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P++TW K + + R +G+ L I +D G YTC N ++
Sbjct: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
Query: 2782 VNFTGRES 2789
++ G +S
Sbjct: 248 LSIQGLDS 255
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 1018 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1075
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+ D Y C +N+ G S + V P+ E + P +R
Sbjct: 1076 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 1028 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 1084
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 1085 SVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1130
Score = 38.3 bits (85), Expect = 0.48
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1079
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 1080 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1171
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 1679 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1729
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPD-VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
G V+++ + S+ + D +P ++ P FI PR+ +EG T E V G P+
Sbjct: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
Query: 3413 PDVYWLRD 3420
P V W R+
Sbjct: 62 PQVTWHRN 69
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 109 bits (263), Expect = 1e-22
Identities = 72/254 (28%), Positives = 123/254 (48%), Gaps = 17/254 (6%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+ P+F+ ++D + + VL+C +RG P+P+ITW + + I +Y GV
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 498
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L I + PED GTYTC AEN++ + +V ++S + + +
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL------LPVAPSKPT 552
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGL-YT 2869
P F L+D +V G + + V++ G P V WL G + E F ++G ++
Sbjct: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE--SEDFHFEQRGTQHS 610
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L + +V ++G YTC AW++ G V A +TV +P DG + +P + + S+G+
Sbjct: 611 LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKP-RSVTASLGQ 667
Query: 2930 DINISFRTQGEPKP 2943
+ IS G+P P
Sbjct: 668 SVLISCAIAGDPFP 681
Score = 102 bits (245), Expect = 2e-20
Identities = 92/329 (27%), Positives = 132/329 (40%), Gaps = 15/329 (4%)
Query: 3042 GVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQ 3101
G+ + P F +L ++ G+ L CSV+G PVP + W+ NG ++ R T +
Sbjct: 437 GLAVMEVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY--ARSTCE 493
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+ L I+D +D G Y+C A N G+ S A + TV E + K E
Sbjct: 494 AGVAE--LHIQDALPEDHGTYTCLAENALGQVSCSAWV------TVHEKKSSRKSEYLLP 545
Query: 3162 VEGDYP--PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
V P P F L D +V V +T QV G+PPP+V W +G E+ + + Q
Sbjct: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
H+L I +D G Y A N++G V L V + P F +
Sbjct: 606 GTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP-HDGTQPWFISKPRSV-TA 663
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + IS + P V W RDG L L + L L V AG Y
Sbjct: 664 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
N VG S + + + + PR
Sbjct: 724 EILLKNRVGECSCQVSLMLQNSSARALPR 752
Score = 96.7 bits (230), Expect = 1e-18
Identities = 80/266 (30%), Positives = 112/266 (42%), Gaps = 35/266 (13%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P F+ L+D V L C V G+P P+++W +G+ + Y + + + H +
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA 504
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD--KGIRA--YV---------APEFCCGLE 3274
P +D G Y A N G VSC + V K R Y+ AP F GL
Sbjct: 505 LP---EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
Query: 3275 PLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR 3334
L K+ +G ++ ++ V P V W +G ++ S R Q L + V
Sbjct: 562 DL-KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLWIQEVFPE 619
Query: 3335 DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE 3394
D G YTC A N G T + V EP +P FI KPRS
Sbjct: 620 DTGTYTCEAWNSAGEVRTQAVLTV------QEPHD-----------GTQPWFISKPRSVT 662
Query: 3395 AREGDTVIIECEVVGDPKPDVYWLRD 3420
A G +V+I C + GDP P V+WLRD
Sbjct: 663 ASLGQSVLISCAIAGDPFPTVHWLRD 688
Score = 90.6 bits (215), Expect = 9e-17
Identities = 74/304 (24%), Positives = 127/304 (41%), Gaps = 39/304 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLE 2652
P FS+ L D +EG L CSV + P +TW NG ++Y + + G+ L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEAGVAELH 500
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY------------PSFEASPIPPTFTRSI 2700
+ +A+P D Y+C EN G +S SA + V+ P + P P F + +
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
Query: 2701 RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D + +++ + ++ G P P++ W + +I + F L I PE
Sbjct: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLWIQEVFPE 619
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D+GTYTC+A NS V + ++ + +P F +
Sbjct: 620 DTGTYTCEAWNSA--------------------GEVRTQAVLTVQEPHDGTQPWFISKPR 659
Query: 2821 DYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
+ G ++ + I G P V WLR+G+++ + + V + ++TL L V
Sbjct: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
Query: 2880 SGLY 2883
+G Y
Sbjct: 720 AGQY 723
Score = 85.0 bits (201), Expect = 4e-15
Identities = 64/232 (27%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P F+ + P L I G TA V+G P P V W +NG + +
Sbjct: 31 EAPAFI-LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV-----------VTDRTVWEADAKLKR 3156
L I ++ +D G+Y+CEATN G L V V +T+ + +
Sbjct: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
E + G+ PP+F +L V+ R +C++ G P P+V+W K + R +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYV 3265
+ LEI N DD GVY N SG S L + D R++V
Sbjct: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261
Score = 71.7 bits (168), Expect = 4e-11
Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 4/181 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F L+D ++GS+V +T V + P V W NG + + + +L +
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 613
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ Y+C N G + T A L V + + P F R +++
Sbjct: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ--PWFISKPRSVTASLGQSVLI 671
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C I G P P + W +D K + D G ++ D V L + P +G Y +N
Sbjct: 672 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNR 730
Query: 2773 V 2773
V
Sbjct: 731 V 731
Score = 70.1 bits (164), Expect = 1e-10
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 1080
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ PED G Y C A+N + + V T ++ S N E
Sbjct: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 1131
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 1132 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 1183
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W + V+ S+ K ++ R E +
Sbjct: 1184 ESVELFGKVTGTQP--ITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 1241 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 1300 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1356
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 1357 EKPEEPK 1363
Score = 69.7 bits (163), Expect = 2e-10
Identities = 55/199 (27%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
E R+RG P P++TW ++ + I S GR+ G L I ED G YTC+A N
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
Query: 2774 WTDQITHFVNFTGR-ESQVSPNVVTAE-KTRIARQSLESR-------RPHFGNVLTDYQV 2824
Q+T + G Q+ VV+ R + ++E+R P F L V
Sbjct: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVV 172
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G +I G P +V WL+ G + V + G+ L + V + + G+Y
Sbjct: 173 KEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
Query: 2884 TCRAWSAHGNVDMNAAITV 2902
TC + G M+A +++
Sbjct: 232 TCLVVNGSGKASMSAELSI 250
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 1734 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1793
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 1794 GNCSLIISDVCGDDDAKYTCKAVNSL 1819
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 1749 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1808
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 1809 AKYTCKAVNSLGEATCTAELIVET 1832
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 12/153 (7%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG + V YP VTW+R+G + R ++ G L + AV D G
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
Query: 3339 YTCTASNEVGRASTSGKVEVIGT--DQTSEPRI----------PPVVISPDVPYSKEPMF 3386
YTC A+N G + ++ V G+ Q +P + V P + P F
Sbjct: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKF 163
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
K +EG C++ G P+P V WL+
Sbjct: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Score = 59.3 bits (137), Expect = 2e-07
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI 3324
VAP F L+ + EG + + V P +TW +G +P + A T + G
Sbjct: 443 VAPSFSSVLKDCAVI-EGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEA-GVA 497
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG--TDQTSEPRIPPVVISPDVPYSK 3382
EL + D G YTC A N +G+ S S V V + + SE +P ++P P +
Sbjct: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP---VAPSKPTA- 553
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P+F++ + +G V + +V G+P P+V WL +
Sbjct: 554 -PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 1735 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1793
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 1794 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 54.4 bits (125), Expect = 7e-06
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG R S + P VTW + V L+PS R ++ +++G L + V D GVYT
Sbjct: 174 EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYT 232
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTS 3365
C N G+AS S ++ + G D +
Sbjct: 233 CLVVNGSGKASMSAELSIQGLDSAN 257
Score = 53.2 bits (122), Expect = 2e-05
Identities = 62/275 (22%), Positives = 104/275 (37%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 989 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 1047
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ +D G Y C A N
Sbjct: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALPEDRGLYKCVAKND 1106
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 1729 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1788
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 1789 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831
Score = 48.4 bits (110), Expect = 5e-04
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 1018 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1075
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+P D Y C +N+ G S + V P+ E + P +R
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 1739 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1798
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+T L EG + +C + P VTW + V L + +G+ LE+
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D Y+C V N +G S SA L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 1739 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1798
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1839
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 29/248 (11%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR 2629
S S+ + R S T P F + EG+ K V +P VTW+R
Sbjct: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
Query: 2630 NGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
NG + + ++ + G +L + D +Y+C N +GA + L V SF
Sbjct: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Query: 2689 ASPIPPTFTRSIRDTFHLAENE----LVLEC---------RI---RGQ-----------P 2721
P ++++ D F + E + EC R+ GQ P
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P++TW K + + R +G+ L I +D G YTC N ++
Sbjct: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
Query: 2782 VNFTGRES 2789
++ G +S
Sbjct: 248 LSIQGLDS 255
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 1028 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 1084
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1130
Score = 39.1 bits (87), Expect = 0.28
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1079
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1171
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 1731 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1781
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPD-VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
G V+++ + S+ + D +P ++ P FI PR+ +EG T E V G P+
Sbjct: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
Query: 3413 PDVYWLRD 3420
P V W R+
Sbjct: 62 PQVTWHRN 69
>AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein
protein.
Length = 1391
Score = 109 bits (262), Expect = 2e-22
Identities = 93/330 (28%), Positives = 142/330 (43%), Gaps = 19/330 (5%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG-FDCCLTIKDINIDDE 3119
++ G TC + G PVP V W K+G ++ + R + G C L I+ DD+
Sbjct: 1026 RVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDDD 1085
Query: 3120 GRYSCEATNTHGKASTYARLAV--VTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
G Y+ A N G+ S L V + R+ + + R RS E D P R
Sbjct: 1086 GNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPH 1145
Query: 3178 RVQATYPV--------RLTCQVIGSPPPKVSWYKDGEEVVYD-KRRNKYQDEQFHTLEIA 3228
+QA + RL C+V G PPP+++W +G+ V+ D + ++ H+L I
Sbjct: 1146 FLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLID 1205
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
P D G Y+ A N +G S L VV K ++ AP L+ + EG +R+
Sbjct: 1206 PLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK--APVILEKLQNC-GVPEGHPVRL 1262
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAI-MTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
V P W +D + +R I M D G L + DAG YT +A NE
Sbjct: 1263 ECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNE 1322
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISP 3376
G S + ++++ P PP+ + P
Sbjct: 1323 AGIVSCTARLDIYAQWHHQIP--PPMSVRP 1350
Score = 89.8 bits (213), Expect = 1e-16
Identities = 68/206 (33%), Positives = 93/206 (45%), Gaps = 23/206 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDC 3107
RP F+ PG + G L C V G P P + W+ NG V +A +M + G
Sbjct: 1143 RPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVH- 1200
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I + D G Y C ATN G+ S L+VV K + A
Sbjct: 1201 SLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVA-----------KEVKKA------- 1242
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P +L++ V +PVRL C+VIG PPP W KD E + + R + +QD + L
Sbjct: 1243 PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACL 1302
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P D G Y ++A+N +G VSC
Sbjct: 1303 LIQPAKKSDAGWYTLSAKNEAGIVSC 1328
Score = 83.8 bits (198), Expect = 1e-14
Identities = 67/265 (25%), Positives = 116/265 (43%), Gaps = 19/265 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPS-DGRYQAFYLADGV 2749
I P F + ++ F + E V C+I G P+PK+ WFKD KQI + R + DG
Sbjct: 1014 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGT 1072
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
C L I++ T +D G YT A N +I+ + + + + +A ++ R ++
Sbjct: 1073 CSLHIESTTSDDDGNYTIMAANP--QGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1130
Query: 2810 SR----------RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
R RPHF D G L ++ G P + WL G+ V +
Sbjct: 1131 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPH 1190
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G+++L + +T+ ++G Y C A + G + ++VV + K A ++
Sbjct: 1191 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK---EVKKAPVILE 1247
Query: 2919 PEKDILISVGEDINISFRTQGEPKP 2943
++ + G + + R G P P
Sbjct: 1248 KLQNCGVPEGHPVRLECRVIGMPPP 1272
Score = 70.1 bits (164), Expect = 1e-10
Identities = 56/232 (24%), Positives = 95/232 (40%), Gaps = 30/232 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL---DNKLKYRKKLVDGLIT 2650
P+F L EGS V TC ++ P V W+++G + + + K R++ DG +
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRRE-GDGTCS 1074
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVY------------------PSFEASPI 2692
L + + D Y+ N G IS S +L V +
Sbjct: 1075 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDK 1134
Query: 2693 PPTFTRSIRDTFHLAENELV--------LECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
P R R F A ++V L+C++ G P P++TW + + + D ++
Sbjct: 1135 EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLV 1194
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
GV L ID T D+GTY C A N + + ++ +E + +P ++
Sbjct: 1195 RETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 1246
Score = 68.5 bits (160), Expect = 4e-10
Identities = 37/92 (40%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--L 3225
P F RL+ RV PV TC+++G P PKV W+KDG+++ R K + E T L
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSL 1075
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I T DD G Y + A N G +SC L+V
Sbjct: 1076 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1107
Score = 64.5 bits (150), Expect = 6e-09
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
HEG R+ V P +TW +G + P M + G L + +T RDAG Y
Sbjct: 1156 HEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTY 1215
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N+ G+ S S ++ V+ + K P+ + K ++ EG
Sbjct: 1216 KCIATNKTGQNSFSLELSVVAKE-----------------VKKAPVILEKLQNCGVPEGH 1258
Query: 3400 TVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P YW +D
Sbjct: 1259 PVRLECRVIGMPPPVFYWKKD 1279
Score = 62.5 bits (145), Expect = 3e-08
Identities = 33/92 (35%), Positives = 47/92 (51%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP+FT +LR R V V+L C V+G PPP+V WY +G+E+ + Q H+L
Sbjct: 339 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 398
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
IA +D G Y A N G S + ++
Sbjct: 399 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 430
Score = 60.9 bits (141), Expect = 8e-08
Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 6/182 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLIT 2650
+P F D A EG +L C V P +TW NG VL D K + G+ +
Sbjct: 1143 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRET-GVHS 1201
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + D+ Y C N+ G S S L V E P +++ +
Sbjct: 1202 LLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK-EVKKAP-VILEKLQNCGVPEGHP 1259
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ LECR+ G P P W KD++ IP + R G L I D+G YT A
Sbjct: 1260 VRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSA 1319
Query: 2770 EN 2771
+N
Sbjct: 1320 KN 1321
Score = 60.1 bits (139), Expect = 1e-07
Identities = 45/166 (27%), Positives = 73/166 (43%), Gaps = 13/166 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQ 3323
+AP F L+ +++ EG + + + P V W++DG ++ + + R M + DG
Sbjct: 1014 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGT 1072
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-----------IGTDQTSEPRIPPV 3372
L + + T+ D G YT A+N GR S SG + V G R+
Sbjct: 1073 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 1132
Query: 3373 VISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P P F++ P A EG ++C+V G P P++ WL
Sbjct: 1133 DKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWL 1178
Score = 56.0 bits (129), Expect = 2e-06
Identities = 31/90 (34%), Positives = 41/90 (45%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L R EG+RV+L C V+ P V WY G L+N L +L +
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 399
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A D+ YSC N G STSA + +
Sbjct: 400 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR---KK-----LV 2645
PVF+ L + +A EG V C V + P V WYR G L+++ +R KK
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + TL + DS ++CT N+ G +S+ A L V
Sbjct: 566 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 603
Score = 50.4 bits (115), Expect = 1e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE--------EVVYDKRRNKYQD 3219
P FT L++ V C+V G+P PKV WY++G ++ K R+ +
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
E+ TL IA +D G + TA N G VS
Sbjct: 566 EEICTLVIAEVFAEDSGCFTCTASNKYGTVS 596
Score = 49.6 bits (113), Expect = 2e-04
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 2694 PTFTRSIRDTFHLAENELVL-ECRIRGQPLPKITWFKDDKQIPSDGRY-------QAFYL 2745
P FT+ +++ +E +LV+ ECR++G P PK+ W+++ I + ++
Sbjct: 506 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 564
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +C L I EDSG +TC A N T
Sbjct: 565 PEEICTLVIAEVFAEDSGCFTCTASNKYGT 594
Score = 48.4 bits (110), Expect = 5e-04
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 3047 GDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
G P F L + ++ G L C V G P P V W G E+E Q
Sbjct: 337 GQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 395
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
LTI + +D GRYSC A+N +G ST A + +
Sbjct: 396 S-LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429
Score = 46.4 bits (105), Expect = 0.002
Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR--PSRRAIMTLDRD-G 3322
AP F L+ L EG + V+ PS V WYR+G + P R + R
Sbjct: 505 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 563
Query: 3323 QIE----LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ E L +A V D+G +TCTASN+ G S+ ++ V G + S
Sbjct: 564 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 610
Score = 45.6 bits (103), Expect = 0.003
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 6/124 (4%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP FT+ +R + L+C + G P P++ W+ + K++ + A + L
Sbjct: 339 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH-IVQAGNLHSL 397
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG---RESQVSPNVVTAEKTRIARQSLE 2809
I ED+G Y+C A N TD + + G +S+ PN E RI + +
Sbjct: 398 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPN--KEEMNRIQKPNEV 455
Query: 2810 SRRP 2813
S P
Sbjct: 456 SSPP 459
Score = 44.4 bits (100), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTE------VYRNARVFVE- 2864
P F +L + + G + + ++G P+ +VEW REG + + + + R E
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + TL +++V +SG +TC A + +G V A + V DL
Sbjct: 566 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 609
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD--- 3106
P F +L L G+ C VKG P P V W + G +E+ Q
Sbjct: 506 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 564
Query: 3107 ----CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
C L I ++ +D G ++C A+N +G S+ A+L V
Sbjct: 565 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 603
Score = 43.6 bits (98), Expect = 0.013
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 3333 TRDAGVYTCTASNEVGRASTSGKV-EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
TRD V E R E G D T P P + + P + P F +K R
Sbjct: 290 TRDNEVNHALEQQEAKRREAEQAASEAAGGDTT--PGSSPSSLYYEEPLGQPPRFTQKLR 347
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYW 3417
S E EG V ++C VVG P P V W
Sbjct: 348 SREVPEGTRVQLDCIVVGIPPPQVRW 373
Score = 42.7 bits (96), Expect = 0.022
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG +++ +V P V WY +G L S I + L +A D G Y+
Sbjct: 353 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD-IHIVQAGNLHSLTIAEAFEEDTGRYS 411
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
C ASN G STS ++ + G + P
Sbjct: 412 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP 441
Score = 41.9 bits (94), Expect = 0.039
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
E +++ + PV L + EG V+L C VI P W ++ + +
Sbjct: 1231 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 1290
Query: 2642 KKLVD--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
D G L + A SD+ Y+ + +NE G +S +A L +Y + PP R
Sbjct: 1291 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR 1349
Score = 38.3 bits (85), Expect = 0.48
Identities = 16/42 (38%), Positives = 22/42 (52%)
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+F + ++ A EG V+ EC V G P P V W R+
Sbjct: 501 PIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYRE 542
Score = 37.9 bits (84), Expect = 0.64
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++P K P+F ++ + EG V C++VG P P VYW +D
Sbjct: 1007 EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKD 1052
>AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein
protein.
Length = 1320
Score = 109 bits (262), Expect = 2e-22
Identities = 94/331 (28%), Positives = 145/331 (43%), Gaps = 21/331 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQFNGFDCCLTIKDINIDD 3118
++ G TC + G PVP V W K+G ++ + E +M + +G C L I+ DD
Sbjct: 955 RVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDG-TCSLHIESTTSDD 1013
Query: 3119 EGRYSCEATNTHGKASTYARLAV--VTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+G Y+ A N G+ S L V + R+ + + R RS E D P R
Sbjct: 1014 DGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRP 1073
Query: 3177 RRVQATYPV--------RLTCQVIGSPPPKVSWYKDGEEVVYD-KRRNKYQDEQFHTLEI 3227
+QA + RL C+V G PPP+++W +G+ V+ D + ++ H+L I
Sbjct: 1074 HFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLI 1133
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
P D G Y+ A N +G S L VV K ++ AP L+ + EG +R
Sbjct: 1134 DPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK--APVILEKLQNC-GVPEGHPVR 1190
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAI-MTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ V P W +D + +R I M D G L + DAG YT +A N
Sbjct: 1191 LECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKN 1250
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISP 3376
E G S + ++++ P PP+ + P
Sbjct: 1251 EAGIVSCTARLDIYAQWHHQIP--PPMSVRP 1279
Score = 90.6 bits (215), Expect = 9e-17
Identities = 68/206 (33%), Positives = 93/206 (45%), Gaps = 23/206 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDC 3107
RP F+ PG + G L C V G P P + W+ NG V +A +M + G
Sbjct: 1072 RPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVH- 1129
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I + D G Y C ATN G+ S L+VV K + A
Sbjct: 1130 SLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVA-----------KEVKKA------- 1171
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P +L++ V +PVRL C+VIG PPP W KD E + + R + +QD + L
Sbjct: 1172 PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACL 1231
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P D G Y ++A+N +G VSC
Sbjct: 1232 LIQPAKKSDAGWYTLSAKNEAGIVSC 1257
Score = 83.4 bits (197), Expect = 1e-14
Identities = 66/265 (24%), Positives = 115/265 (43%), Gaps = 19/265 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRY-QAFYLADGV 2749
I P F + ++ F + E V C+I G P+PK+ WFKD KQI + + DG
Sbjct: 943 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
C L I++ T +D G YT A N +I+ + + + + +A ++ R ++
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANP--QGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059
Query: 2810 SR----------RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
R RPHF D G L ++ G P + WL G+ V +
Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 1119
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G+++L + +T+ ++G Y C A + G + ++VV + K A ++
Sbjct: 1120 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK---EVKKAPVILE 1176
Query: 2919 PEKDILISVGEDINISFRTQGEPKP 2943
++ + G + + R G P P
Sbjct: 1177 KLQNCGVPEGHPVRLECRVIGMPPP 1201
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/231 (23%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK--KLVDGLITL 2651
P+F L EGS V TC ++ P V W+++G + + ++ K + DG +L
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVY------------------PSFEASPIP 2693
+ + D Y+ N G IS S +L V +
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE 1064
Query: 2694 PTFTRSIRDTFHLAENELV--------LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYL 2745
P R R F A ++V L+C++ G P P++TW + + + D ++
Sbjct: 1065 PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 1124
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
GV L ID T D+GTY C A N + + ++ +E + +P ++
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 1175
Score = 66.5 bits (155), Expect = 2e-09
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--L 3225
P F RL+ RV PV TC+++G P PKV W+KDG+++ K + E T L
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I T DD G Y + A N G +SC L+V
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 64.9 bits (151), Expect = 5e-09
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
HEG R+ V P +TW +G + P M + G L + +T RDAG Y
Sbjct: 1085 HEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 1144
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N+ G+ S S ++ V+ + K P+ + K ++ EG
Sbjct: 1145 KCIATNKTGQNSFSLELSVVAKE-----------------VKKAPVILEKLQNCGVPEGH 1187
Query: 3400 TVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P YW +D
Sbjct: 1188 PVRLECRVIGMPPPVFYWKKD 1208
Score = 62.5 bits (145), Expect = 3e-08
Identities = 33/92 (35%), Positives = 47/92 (51%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP+FT +LR R V V+L C V+G PPP+V WY +G+E+ + Q H+L
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
IA +D G Y A N G S + ++
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 6/182 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLIT 2650
+P F D A EG +L C V P +TW NG VL D K + G+ +
Sbjct: 1072 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRET-GVHS 1130
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + D+ Y C N+ G S S L V E P +++ +
Sbjct: 1131 LLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK-EVKKAP-VILEKLQNCGVPEGHP 1188
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ LECR+ G P P W KD++ IP + R G L I D+G YT A
Sbjct: 1189 VRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSA 1248
Query: 2770 EN 2771
+N
Sbjct: 1249 KN 1250
Score = 58.0 bits (134), Expect = 6e-07
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 13/166 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQ 3323
+AP F L+ +++ EG + + + P V W++DG ++ + + M + DG
Sbjct: 943 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-----------IGTDQTSEPRIPPV 3372
L + + T+ D G YT A+N GR S SG + V G R+
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 1061
Query: 3373 VISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P P F++ P A EG ++C+V G P P++ WL
Sbjct: 1062 DKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWL 1107
Score = 56.0 bits (129), Expect = 2e-06
Identities = 31/90 (34%), Positives = 41/90 (45%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L R EG+RV+L C V+ P V WY G L+N L +L +
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A D+ YSC N G STSA + +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 50.8 bits (116), Expect = 8e-05
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR---KK-----LV 2645
PVF+ L + +A EG V C V + P V WYR G L+++ +R KK
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEP 494
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + TL + S ++CT N+ G +S+ A L V
Sbjct: 495 EEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHV 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 3047 GDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
G P F L + ++ G L C V G P P V W G E+E Q
Sbjct: 266 GQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 324
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
LTI + +D GRYSC A+N +G ST A + +
Sbjct: 325 S-LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 2694 PTFTRSIRDTFHLAENELVL-ECRIRGQPLPKITWFKDDKQIP-------SDGRYQAFYL 2745
P FT+ +++ +E +LV+ ECR++G P PK+ W+++ I S + ++
Sbjct: 435 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAE 493
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +C L I E SG +TC A N T
Sbjct: 494 PEEICTLVIAEVFAEGSGCFTCTASNKYGT 523
Score = 46.4 bits (105), Expect = 0.002
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE--------EVVYDKRRNKYQD 3219
P FT L++ V C+V G+P PKV WY++G + K R+ +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEP 494
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
E+ TL IA + G + TA N G VS
Sbjct: 495 EEICTLVIAEVFAEGSGCFTCTASNKYGTVS 525
Score = 45.6 bits (103), Expect = 0.003
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 6/124 (4%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP FT+ +R + L+C + G P P++ W+ + K++ + A + L
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH-IVQAGNLHSL 326
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG---RESQVSPNVVTAEKTRIARQSLE 2809
I ED+G Y+C A N TD + + G +S+ PN E RI + +
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPN--KEEMNRIQKPNEV 384
Query: 2810 SRRP 2813
S P
Sbjct: 385 SSPP 388
Score = 44.0 bits (99), Expect = 0.010
Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 8/107 (7%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL------RPSRRAIMTLD 3319
AP F L+ L EG + V+ PS V WYR+G + R S++ ++
Sbjct: 434 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMA 492
Query: 3320 RDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+I L +A V +G +TCTASN+ G S+ ++ V G + S
Sbjct: 493 EPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 539
Score = 43.6 bits (98), Expect = 0.013
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 3333 TRDAGVYTCTASNEVGRASTSGKV-EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
TRD V E R E G D T P P + + P + P F +K R
Sbjct: 219 TRDNEVNHALEQQEAKRREAEQAASEAAGGDTT--PGSSPSSLYYEEPLGQPPRFTQKLR 276
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYW 3417
S E EG V ++C VVG P P V W
Sbjct: 277 SREVPEGTRVQLDCIVVGIPPPQVRW 302
Score = 43.6 bits (98), Expect = 0.013
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD--- 3106
P F +L L G+ C VKG P P V W + G +E+ SQ
Sbjct: 435 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAE 493
Query: 3107 ----CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
C L I ++ + G ++C A+N +G S+ A+L V
Sbjct: 494 PEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHV 532
Score = 42.7 bits (96), Expect = 0.022
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG +++ +V P V WY +G L S I + L +A D G Y+
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD-IHIVQAGNLHSLTIAEAFEEDTGRYS 340
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
C ASN G STS ++ + G + P
Sbjct: 341 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP 370
Score = 41.9 bits (94), Expect = 0.039
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
E +++ + PV L + EG V+L C VI P W ++ + +
Sbjct: 1160 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 1219
Query: 2642 KKLVD--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
D G L + A SD+ Y+ + +NE G +S +A L +Y + PP R
Sbjct: 1220 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR 1278
Score = 38.3 bits (85), Expect = 0.48
Identities = 16/42 (38%), Positives = 22/42 (52%)
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+F + ++ A EG V+ EC V G P P V W R+
Sbjct: 430 PIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYRE 471
Score = 37.9 bits (84), Expect = 0.64
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++P K P+F ++ + EG V C++VG P P VYW +D
Sbjct: 936 EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKD 981
>AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1320
Score = 109 bits (262), Expect = 2e-22
Identities = 94/331 (28%), Positives = 145/331 (43%), Gaps = 21/331 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQFNGFDCCLTIKDINIDD 3118
++ G TC + G PVP V W K+G ++ + E +M + +G C L I+ DD
Sbjct: 955 RVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDG-TCSLHIESTTSDD 1013
Query: 3119 EGRYSCEATNTHGKASTYARLAV--VTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+G Y+ A N G+ S L V + R+ + + R RS E D P R
Sbjct: 1014 DGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRP 1073
Query: 3177 RRVQATYPV--------RLTCQVIGSPPPKVSWYKDGEEVVYD-KRRNKYQDEQFHTLEI 3227
+QA + RL C+V G PPP+++W +G+ V+ D + ++ H+L I
Sbjct: 1074 HFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLI 1133
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
P D G Y+ A N +G S L VV K ++ AP L+ + EG +R
Sbjct: 1134 DPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK--APVILEKLQNC-GVPEGHPVR 1190
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAI-MTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ V P W +D + +R I M D G L + DAG YT +A N
Sbjct: 1191 LECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKN 1250
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISP 3376
E G S + ++++ P PP+ + P
Sbjct: 1251 EAGIVSCTARLDIYAQWHHQIP--PPMSVRP 1279
Score = 90.6 bits (215), Expect = 9e-17
Identities = 68/206 (33%), Positives = 93/206 (45%), Gaps = 23/206 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDC 3107
RP F+ PG + G L C V G P P + W+ NG V +A +M + G
Sbjct: 1072 RPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVH- 1129
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I + D G Y C ATN G+ S L+VV K + A
Sbjct: 1130 SLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVA-----------KEVKKA------- 1171
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P +L++ V +PVRL C+VIG PPP W KD E + + R + +QD + L
Sbjct: 1172 PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACL 1231
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P D G Y ++A+N +G VSC
Sbjct: 1232 LIQPAKKSDAGWYTLSAKNEAGIVSC 1257
Score = 83.4 bits (197), Expect = 1e-14
Identities = 66/265 (24%), Positives = 115/265 (43%), Gaps = 19/265 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRY-QAFYLADGV 2749
I P F + ++ F + E V C+I G P+PK+ WFKD KQI + + DG
Sbjct: 943 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
C L I++ T +D G YT A N +I+ + + + + +A ++ R ++
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANP--QGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059
Query: 2810 SR----------RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
R RPHF D G L ++ G P + WL G+ V +
Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 1119
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G+++L + +T+ ++G Y C A + G + ++VV + K A ++
Sbjct: 1120 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK---EVKKAPVILE 1176
Query: 2919 PEKDILISVGEDINISFRTQGEPKP 2943
++ + G + + R G P P
Sbjct: 1177 KLQNCGVPEGHPVRLECRVIGMPPP 1201
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/231 (23%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK--KLVDGLITL 2651
P+F L EGS V TC ++ P V W+++G + + ++ K + DG +L
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVY------------------PSFEASPIP 2693
+ + D Y+ N G IS S +L V +
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE 1064
Query: 2694 PTFTRSIRDTFHLAENELV--------LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYL 2745
P R R F A ++V L+C++ G P P++TW + + + D ++
Sbjct: 1065 PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 1124
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
GV L ID T D+GTY C A N + + ++ +E + +P ++
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 1175
Score = 66.5 bits (155), Expect = 2e-09
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--L 3225
P F RL+ RV PV TC+++G P PKV W+KDG+++ K + E T L
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I T DD G Y + A N G +SC L+V
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 64.9 bits (151), Expect = 5e-09
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
HEG R+ V P +TW +G + P M + G L + +T RDAG Y
Sbjct: 1085 HEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 1144
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N+ G+ S S ++ V+ + K P+ + K ++ EG
Sbjct: 1145 KCIATNKTGQNSFSLELSVVAKE-----------------VKKAPVILEKLQNCGVPEGH 1187
Query: 3400 TVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P YW +D
Sbjct: 1188 PVRLECRVIGMPPPVFYWKKD 1208
Score = 62.5 bits (145), Expect = 3e-08
Identities = 33/92 (35%), Positives = 47/92 (51%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP+FT +LR R V V+L C V+G PPP+V WY +G+E+ + Q H+L
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
IA +D G Y A N G S + ++
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 6/182 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLIT 2650
+P F D A EG +L C V P +TW NG VL D K + G+ +
Sbjct: 1072 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRET-GVHS 1130
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + D+ Y C N+ G S S L V E P +++ +
Sbjct: 1131 LLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK-EVKKAP-VILEKLQNCGVPEGHP 1188
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ LECR+ G P P W KD++ IP + R G L I D+G YT A
Sbjct: 1189 VRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSA 1248
Query: 2770 EN 2771
+N
Sbjct: 1249 KN 1250
Score = 58.0 bits (134), Expect = 6e-07
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 13/166 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQ 3323
+AP F L+ +++ EG + + + P V W++DG ++ + + M + DG
Sbjct: 943 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-----------IGTDQTSEPRIPPV 3372
L + + T+ D G YT A+N GR S SG + V G R+
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 1061
Query: 3373 VISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P P F++ P A EG ++C+V G P P++ WL
Sbjct: 1062 DKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWL 1107
Score = 56.0 bits (129), Expect = 2e-06
Identities = 31/90 (34%), Positives = 41/90 (45%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L R EG+RV+L C V+ P V WY G L+N L +L +
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A D+ YSC N G STSA + +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR---KK-----LV 2645
PVF+ L + +A EG V C V + P V WYR G L+++ +R KK
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + TL + DS ++CT N+ G +S+ A L V
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 50.4 bits (115), Expect = 1e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE--------EVVYDKRRNKYQD 3219
P FT L++ V C+V G+P PKV WY++G ++ K R+ +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
E+ TL IA +D G + TA N G VS
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVS 525
Score = 49.6 bits (113), Expect = 2e-04
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 2694 PTFTRSIRDTFHLAENELVL-ECRIRGQPLPKITWFKDDKQIPSDGRY-------QAFYL 2745
P FT+ +++ +E +LV+ ECR++G P PK+ W+++ I + ++
Sbjct: 435 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +C L I EDSG +TC A N T
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGT 523
Score = 48.4 bits (110), Expect = 5e-04
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 3047 GDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
G P F L + ++ G L C V G P P V W G E+E Q
Sbjct: 266 GQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 324
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
LTI + +D GRYSC A+N +G ST A + +
Sbjct: 325 S-LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 46.4 bits (105), Expect = 0.002
Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR--PSRRAIMTLDRD-G 3322
AP F L+ L EG + V+ PS V WYR+G + P R + R
Sbjct: 434 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492
Query: 3323 QIE----LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ E L +A V D+G +TCTASN+ G S+ ++ V G + S
Sbjct: 493 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 539
Score = 45.6 bits (103), Expect = 0.003
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 6/124 (4%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP FT+ +R + L+C + G P P++ W+ + K++ + A + L
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH-IVQAGNLHSL 326
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG---RESQVSPNVVTAEKTRIARQSLE 2809
I ED+G Y+C A N TD + + G +S+ PN E RI + +
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPN--KEEMNRIQKPNEV 384
Query: 2810 SRRP 2813
S P
Sbjct: 385 SSPP 388
Score = 44.4 bits (100), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTE------VYRNARVFVE- 2864
P F +L + + G + + ++G P+ +VEW REG + + + + R E
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + TL +++V +SG +TC A + +G V A + V DL
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD--- 3106
P F +L L G+ C VKG P P V W + G +E+ Q
Sbjct: 435 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 3107 ----CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
C L I ++ +D G ++C A+N +G S+ A+L V
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 43.6 bits (98), Expect = 0.013
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 3333 TRDAGVYTCTASNEVGRASTSGKV-EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
TRD V E R E G D T P P + + P + P F +K R
Sbjct: 219 TRDNEVNHALEQQEAKRREAEQAASEAAGGDTT--PGSSPSSLYYEEPLGQPPRFTQKLR 276
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYW 3417
S E EG V ++C VVG P P V W
Sbjct: 277 SREVPEGTRVQLDCIVVGIPPPQVRW 302
Score = 42.7 bits (96), Expect = 0.022
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG +++ +V P V WY +G L S I + L +A D G Y+
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD-IHIVQAGNLHSLTIAEAFEEDTGRYS 340
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
C ASN G STS ++ + G + P
Sbjct: 341 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP 370
Score = 41.9 bits (94), Expect = 0.039
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
E +++ + PV L + EG V+L C VI P W ++ + +
Sbjct: 1160 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 1219
Query: 2642 KKLVD--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
D G L + A SD+ Y+ + +NE G +S +A L +Y + PP R
Sbjct: 1220 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR 1278
Score = 38.3 bits (85), Expect = 0.48
Identities = 16/42 (38%), Positives = 22/42 (52%)
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+F + ++ A EG V+ EC V G P P V W R+
Sbjct: 430 PIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYRE 471
Score = 37.9 bits (84), Expect = 0.64
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++P K P+F ++ + EG V C++VG P P VYW +D
Sbjct: 936 EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKD 981
>AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1045
Score = 109 bits (262), Expect = 2e-22
Identities = 94/331 (28%), Positives = 145/331 (43%), Gaps = 21/331 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQFNGFDCCLTIKDINIDD 3118
++ G TC + G PVP V W K+G ++ + E +M + +G C L I+ DD
Sbjct: 680 RVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDG-TCSLHIESTTSDD 738
Query: 3119 EGRYSCEATNTHGKASTYARLAV--VTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+G Y+ A N G+ S L V + R+ + + R RS E D P R
Sbjct: 739 DGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRP 798
Query: 3177 RRVQATYPV--------RLTCQVIGSPPPKVSWYKDGEEVVYD-KRRNKYQDEQFHTLEI 3227
+QA + RL C+V G PPP+++W +G+ V+ D + ++ H+L I
Sbjct: 799 HFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLI 858
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
P D G Y+ A N +G S L VV K ++ AP L+ + EG +R
Sbjct: 859 DPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK--APVILEKLQNC-GVPEGHPVR 915
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAI-MTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ V P W +D + +R I M D G L + DAG YT +A N
Sbjct: 916 LECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKN 975
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISP 3376
E G S + ++++ P PP+ + P
Sbjct: 976 EAGIVSCTARLDIYAQWHHQIP--PPMSVRP 1004
Score = 90.6 bits (215), Expect = 9e-17
Identities = 68/206 (33%), Positives = 93/206 (45%), Gaps = 23/206 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDC 3107
RP F+ PG + G L C V G P P + W+ NG V +A +M + G
Sbjct: 797 RPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVH- 854
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I + D G Y C ATN G+ S L+VV K + A
Sbjct: 855 SLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVA-----------KEVKKA------- 896
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P +L++ V +PVRL C+VIG PPP W KD E + + R + +QD + L
Sbjct: 897 PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACL 956
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P D G Y ++A+N +G VSC
Sbjct: 957 LIQPAKKSDAGWYTLSAKNEAGIVSC 982
Score = 83.4 bits (197), Expect = 1e-14
Identities = 66/265 (24%), Positives = 115/265 (43%), Gaps = 19/265 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRY-QAFYLADGV 2749
I P F + ++ F + E V C+I G P+PK+ WFKD KQI + + DG
Sbjct: 668 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 726
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
C L I++ T +D G YT A N +I+ + + + + +A ++ R ++
Sbjct: 727 CSLHIESTTSDDDGNYTIMAANP--QGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 784
Query: 2810 SR----------RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
R RPHF D G L ++ G P + WL G+ V +
Sbjct: 785 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 844
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G+++L + +T+ ++G Y C A + G + ++VV + K A ++
Sbjct: 845 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK---EVKKAPVILE 901
Query: 2919 PEKDILISVGEDINISFRTQGEPKP 2943
++ + G + + R G P P
Sbjct: 902 KLQNCGVPEGHPVRLECRVIGMPPP 926
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/231 (23%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK--KLVDGLITL 2651
P+F L EGS V TC ++ P V W+++G + + ++ K + DG +L
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVY------------------PSFEASPIP 2693
+ + D Y+ N G IS S +L V +
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE 789
Query: 2694 PTFTRSIRDTFHLAENELV--------LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYL 2745
P R R F A ++V L+C++ G P P++TW + + + D ++
Sbjct: 790 PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 849
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
GV L ID T D+GTY C A N + + ++ +E + +P ++
Sbjct: 850 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 900
Score = 66.5 bits (155), Expect = 2e-09
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--L 3225
P F RL+ RV PV TC+++G P PKV W+KDG+++ K + E T L
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I T DD G Y + A N G +SC L+V
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 64.9 bits (151), Expect = 5e-09
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
HEG R+ V P +TW +G + P M + G L + +T RDAG Y
Sbjct: 810 HEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 869
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N+ G+ S S ++ V+ + K P+ + K ++ EG
Sbjct: 870 KCIATNKTGQNSFSLELSVVAKE-----------------VKKAPVILEKLQNCGVPEGH 912
Query: 3400 TVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P YW +D
Sbjct: 913 PVRLECRVIGMPPPVFYWKKD 933
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 6/182 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLIT 2650
+P F D A EG +L C V P +TW NG VL D K + G+ +
Sbjct: 797 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRET-GVHS 855
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + D+ Y C N+ G S S L V E P +++ +
Sbjct: 856 LLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK-EVKKAP-VILEKLQNCGVPEGHP 913
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ LECR+ G P P W KD++ IP + R G L I D+G YT A
Sbjct: 914 VRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSA 973
Query: 2770 EN 2771
+N
Sbjct: 974 KN 975
Score = 58.0 bits (134), Expect = 6e-07
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 13/166 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQ 3323
+AP F L+ +++ EG + + + P V W++DG ++ + + M + DG
Sbjct: 668 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 726
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-----------IGTDQTSEPRIPPV 3372
L + + T+ D G YT A+N GR S SG + V G R+
Sbjct: 727 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 786
Query: 3373 VISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P P F++ P A EG ++C+V G P P++ WL
Sbjct: 787 DKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWL 832
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR---KK-----LV 2645
PVF+ L + +A EG V C V + P V WYR G L+++ +R KK
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + TL + DS ++CT N+ G +S+ A L V
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 50.4 bits (115), Expect = 1e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE--------EVVYDKRRNKYQD 3219
P FT L++ V C+V G+P PKV WY++G ++ K R+ +
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
E+ TL IA +D G + TA N G VS
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVS 250
Score = 49.6 bits (113), Expect = 2e-04
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 2694 PTFTRSIRDTFHLAENELVL-ECRIRGQPLPKITWFKDDKQIPSDGRY-------QAFYL 2745
P FT+ +++ +E +LV+ ECR++G P PK+ W+++ I + ++
Sbjct: 160 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +C L I EDSG +TC A N T
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGT 248
Score = 46.4 bits (105), Expect = 0.002
Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR--PSRRAIMTLDRD-G 3322
AP F L+ L EG + V+ PS V WYR+G + P R + R
Sbjct: 159 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217
Query: 3323 QIE----LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ E L +A V D+G +TCTASN+ G S+ ++ V G + S
Sbjct: 218 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 264
Score = 44.4 bits (100), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTE------VYRNARVFVE- 2864
P F +L + + G + + ++G P+ +VEW REG + + + + R E
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + TL +++V +SG +TC A + +G V A + V DL
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD--- 3106
P F +L L G+ C VKG P P V W + G +E+ Q
Sbjct: 160 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 3107 ----CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
C L I ++ +D G ++C A+N +G S+ A+L V
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 41.9 bits (94), Expect = 0.039
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
E +++ + PV L + EG V+L C VI P W ++ + +
Sbjct: 885 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 944
Query: 2642 KKLVD--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
D G L + A SD+ Y+ + +NE G +S +A L +Y + PP R
Sbjct: 945 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR 1003
Score = 38.3 bits (85), Expect = 0.48
Identities = 16/42 (38%), Positives = 22/42 (52%)
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+F + ++ A EG V+ EC V G P P V W R+
Sbjct: 155 PIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYRE 196
Score = 37.9 bits (84), Expect = 0.64
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++P K P+F ++ + EG V C++VG P P VYW +D
Sbjct: 661 EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKD 706
Score = 34.3 bits (75), Expect = 7.9
Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 3083 VWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+W G E+E Q LTI + +D GRYSC A+N +G ST A + +
Sbjct: 26 MWYCEGKELENSPDIHIVQAGNLHS-LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 83
>AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.
Length = 1320
Score = 109 bits (262), Expect = 2e-22
Identities = 94/331 (28%), Positives = 145/331 (43%), Gaps = 21/331 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQFNGFDCCLTIKDINIDD 3118
++ G TC + G PVP V W K+G ++ + E +M + +G C L I+ DD
Sbjct: 955 RVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDG-TCSLHIESTTSDD 1013
Query: 3119 EGRYSCEATNTHGKASTYARLAV--VTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+G Y+ A N G+ S L V + R+ + + R RS E D P R
Sbjct: 1014 DGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRP 1073
Query: 3177 RRVQATYPV--------RLTCQVIGSPPPKVSWYKDGEEVVYD-KRRNKYQDEQFHTLEI 3227
+QA + RL C+V G PPP+++W +G+ V+ D + ++ H+L I
Sbjct: 1074 HFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLI 1133
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
P D G Y+ A N +G S L VV K ++ AP L+ + EG +R
Sbjct: 1134 DPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK--APVILEKLQNC-GVPEGHPVR 1190
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAI-MTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ V P W +D + +R I M D G L + DAG YT +A N
Sbjct: 1191 LECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKN 1250
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISP 3376
E G S + ++++ P PP+ + P
Sbjct: 1251 EAGIVSCTARLDIYAQWHHQIP--PPMSVRP 1279
Score = 90.6 bits (215), Expect = 9e-17
Identities = 68/206 (33%), Positives = 93/206 (45%), Gaps = 23/206 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDC 3107
RP F+ PG + G L C V G P P + W+ NG V +A +M + G
Sbjct: 1072 RPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVH- 1129
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I + D G Y C ATN G+ S L+VV K + A
Sbjct: 1130 SLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVA-----------KEVKKA------- 1171
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P +L++ V +PVRL C+VIG PPP W KD E + + R + +QD + L
Sbjct: 1172 PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACL 1231
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P D G Y ++A+N +G VSC
Sbjct: 1232 LIQPAKKSDAGWYTLSAKNEAGIVSC 1257
Score = 83.4 bits (197), Expect = 1e-14
Identities = 66/265 (24%), Positives = 115/265 (43%), Gaps = 19/265 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRY-QAFYLADGV 2749
I P F + ++ F + E V C+I G P+PK+ WFKD KQI + + DG
Sbjct: 943 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
C L I++ T +D G YT A N +I+ + + + + +A ++ R ++
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANP--QGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059
Query: 2810 SR----------RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
R RPHF D G L ++ G P + WL G+ V +
Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 1119
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G+++L + +T+ ++G Y C A + G + ++VV + K A ++
Sbjct: 1120 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK---EVKKAPVILE 1176
Query: 2919 PEKDILISVGEDINISFRTQGEPKP 2943
++ + G + + R G P P
Sbjct: 1177 KLQNCGVPEGHPVRLECRVIGMPPP 1201
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/231 (23%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK--KLVDGLITL 2651
P+F L EGS V TC ++ P V W+++G + + ++ K + DG +L
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVY------------------PSFEASPIP 2693
+ + D Y+ N G IS S +L V +
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE 1064
Query: 2694 PTFTRSIRDTFHLAENELV--------LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYL 2745
P R R F A ++V L+C++ G P P++TW + + + D ++
Sbjct: 1065 PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 1124
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
GV L ID T D+GTY C A N + + ++ +E + +P ++
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 1175
Score = 66.5 bits (155), Expect = 2e-09
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--L 3225
P F RL+ RV PV TC+++G P PKV W+KDG+++ K + E T L
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I T DD G Y + A N G +SC L+V
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 64.9 bits (151), Expect = 5e-09
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
HEG R+ V P +TW +G + P M + G L + +T RDAG Y
Sbjct: 1085 HEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 1144
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N+ G+ S S ++ V+ + K P+ + K ++ EG
Sbjct: 1145 KCIATNKTGQNSFSLELSVVAKE-----------------VKKAPVILEKLQNCGVPEGH 1187
Query: 3400 TVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P YW +D
Sbjct: 1188 PVRLECRVIGMPPPVFYWKKD 1208
Score = 62.5 bits (145), Expect = 3e-08
Identities = 33/92 (35%), Positives = 47/92 (51%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP+FT +LR R V V+L C V+G PPP+V WY +G+E+ + Q H+L
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
IA +D G Y A N G S + ++
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 6/182 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLIT 2650
+P F D A EG +L C V P +TW NG VL D K + G+ +
Sbjct: 1072 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRET-GVHS 1130
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + D+ Y C N+ G S S L V E P +++ +
Sbjct: 1131 LLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK-EVKKAP-VILEKLQNCGVPEGHP 1188
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ LECR+ G P P W KD++ IP + R G L I D+G YT A
Sbjct: 1189 VRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSA 1248
Query: 2770 EN 2771
+N
Sbjct: 1249 KN 1250
Score = 58.0 bits (134), Expect = 6e-07
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 13/166 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQ 3323
+AP F L+ +++ EG + + + P V W++DG ++ + + M + DG
Sbjct: 943 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-----------IGTDQTSEPRIPPV 3372
L + + T+ D G YT A+N GR S SG + V G R+
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 1061
Query: 3373 VISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P P F++ P A EG ++C+V G P P++ WL
Sbjct: 1062 DKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWL 1107
Score = 56.0 bits (129), Expect = 2e-06
Identities = 31/90 (34%), Positives = 41/90 (45%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L R EG+RV+L C V+ P V WY G L+N L +L +
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A D+ YSC N G STSA + +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR---KK-----LV 2645
PVF+ L + +A EG V C V + P V WYR G L+++ +R KK
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + TL + DS ++CT N+ G +S+ A L V
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 50.4 bits (115), Expect = 1e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE--------EVVYDKRRNKYQD 3219
P FT L++ V C+V G+P PKV WY++G ++ K R+ +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
E+ TL IA +D G + TA N G VS
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVS 525
Score = 49.6 bits (113), Expect = 2e-04
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 2694 PTFTRSIRDTFHLAENELVL-ECRIRGQPLPKITWFKDDKQIPSDGRY-------QAFYL 2745
P FT+ +++ +E +LV+ ECR++G P PK+ W+++ I + ++
Sbjct: 435 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +C L I EDSG +TC A N T
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGT 523
Score = 48.4 bits (110), Expect = 5e-04
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 3047 GDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
G P F L + ++ G L C V G P P V W G E+E Q
Sbjct: 266 GQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 324
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
LTI + +D GRYSC A+N +G ST A + +
Sbjct: 325 S-LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 46.4 bits (105), Expect = 0.002
Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR--PSRRAIMTLDRD-G 3322
AP F L+ L EG + V+ PS V WYR+G + P R + R
Sbjct: 434 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492
Query: 3323 QIE----LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ E L +A V D+G +TCTASN+ G S+ ++ V G + S
Sbjct: 493 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 539
Score = 45.6 bits (103), Expect = 0.003
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 6/124 (4%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP FT+ +R + L+C + G P P++ W+ + K++ + A + L
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH-IVQAGNLHSL 326
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG---RESQVSPNVVTAEKTRIARQSLE 2809
I ED+G Y+C A N TD + + G +S+ PN E RI + +
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPN--KEEMNRIQKPNEV 384
Query: 2810 SRRP 2813
S P
Sbjct: 385 SSPP 388
Score = 44.4 bits (100), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTE------VYRNARVFVE- 2864
P F +L + + G + + ++G P+ +VEW REG + + + + R E
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + TL +++V +SG +TC A + +G V A + V DL
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD--- 3106
P F +L L G+ C VKG P P V W + G +E+ Q
Sbjct: 435 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 3107 ----CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
C L I ++ +D G ++C A+N +G S+ A+L V
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 43.6 bits (98), Expect = 0.013
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 3333 TRDAGVYTCTASNEVGRASTSGKV-EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
TRD V E R E G D T P P + + P + P F +K R
Sbjct: 219 TRDNEVNHALEQQEAKRREAEQAASEAAGGDTT--PGSSPSSLYYEEPLGQPPRFTQKLR 276
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYW 3417
S E EG V ++C VVG P P V W
Sbjct: 277 SREVPEGTRVQLDCIVVGIPPPQVRW 302
Score = 42.7 bits (96), Expect = 0.022
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG +++ +V P V WY +G L S I + L +A D G Y+
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD-IHIVQAGNLHSLTIAEAFEEDTGRYS 340
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
C ASN G STS ++ + G + P
Sbjct: 341 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP 370
Score = 41.9 bits (94), Expect = 0.039
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
E +++ + PV L + EG V+L C VI P W ++ + +
Sbjct: 1160 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 1219
Query: 2642 KKLVD--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
D G L + A SD+ Y+ + +NE G +S +A L +Y + PP R
Sbjct: 1220 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR 1278
Score = 38.3 bits (85), Expect = 0.48
Identities = 16/42 (38%), Positives = 22/42 (52%)
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+F + ++ A EG V+ EC V G P P V W R+
Sbjct: 430 PIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYRE 471
Score = 37.9 bits (84), Expect = 0.64
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++P K P+F ++ + EG V C++VG P P VYW +D
Sbjct: 936 EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKD 981
>AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein
protein.
Length = 1045
Score = 109 bits (261), Expect = 2e-22
Identities = 93/331 (28%), Positives = 143/331 (43%), Gaps = 21/331 (6%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQFNGFDCCLTIKDINIDD 3118
++ G TC + G PVP V W K+G ++ + E +M + +G C L I+ DD
Sbjct: 680 RVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDG-TCSLHIESTTSDD 738
Query: 3119 EGRYSCEATNTHGKASTYARLAV--VTDRTVWEADAKLKRERSAEVEGD--------YPP 3168
+G Y+ A N G+ S L V + R+ + + R RS E D + P
Sbjct: 739 DGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRP 798
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD-KRRNKYQDEQFHTLEI 3227
F D RL C+V G PPP+++W +G+ V+ D + ++ H+L I
Sbjct: 799 HFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLI 858
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
P D G Y+ A N +G S L VV K ++ AP L+ + EG +R
Sbjct: 859 DPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK--APVILEKLQNC-GVPEGHPVR 915
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAI-MTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ V P W +D + +R I M D G L + DAG YT +A N
Sbjct: 916 LECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKN 975
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISP 3376
E G S + ++++ P PP+ + P
Sbjct: 976 EAGIVSCTARLDIYAQWHHQIP--PPMSVRP 1004
Score = 90.6 bits (215), Expect = 9e-17
Identities = 68/206 (33%), Positives = 93/206 (45%), Gaps = 23/206 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDC 3107
RP F+ PG + G L C V G P P + W+ NG V +A +M + G
Sbjct: 797 RPHFLQT-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVH- 854
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I + D G Y C ATN G+ S L+VV K + A
Sbjct: 855 SLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVA-----------KEVKKA------- 896
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTL 3225
P +L++ V +PVRL C+VIG PPP W KD E + + R + +QD + L
Sbjct: 897 PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACL 956
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSC 3251
I P D G Y ++A+N +G VSC
Sbjct: 957 LIQPAKKSDAGWYTLSAKNEAGIVSC 982
Score = 83.4 bits (197), Expect = 1e-14
Identities = 66/265 (24%), Positives = 115/265 (43%), Gaps = 19/265 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRY-QAFYLADGV 2749
I P F + ++ F + E V C+I G P+PK+ WFKD KQI + + DG
Sbjct: 668 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 726
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
C L I++ T +D G YT A N +I+ + + + + +A ++ R ++
Sbjct: 727 CSLHIESTTSDDDGNYTIMAANP--QGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 784
Query: 2810 SR----------RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRN 2858
R RPHF D G L ++ G P + WL G+ V +
Sbjct: 785 ERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 844
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G+++L + +T+ ++G Y C A + G + ++VV + K A ++
Sbjct: 845 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK---EVKKAPVILE 901
Query: 2919 PEKDILISVGEDINISFRTQGEPKP 2943
++ + G + + R G P P
Sbjct: 902 KLQNCGVPEGHPVRLECRVIGMPPP 926
Score = 66.5 bits (155), Expect = 2e-09
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--L 3225
P F RL+ RV PV TC+++G P PKV W+KDG+++ K + E T L
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I T DD G Y + A N G +SC L+V
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 64.9 bits (151), Expect = 5e-09
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
HEG R+ V P +TW +G + P M + G L + +T RDAG Y
Sbjct: 810 HEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 869
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N+ G+ S S ++ V+ + K P+ + K ++ EG
Sbjct: 870 KCIATNKTGQNSFSLELSVVAKE-----------------VKKAPVILEKLQNCGVPEGH 912
Query: 3400 TVIIECEVVGDPKPDVYWLRD 3420
V +EC V+G P P YW +D
Sbjct: 913 PVRLECRVIGMPPPVFYWKKD 933
Score = 64.5 bits (150), Expect = 6e-09
Identities = 54/231 (23%), Positives = 91/231 (39%), Gaps = 28/231 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK--KLVDGLITL 2651
P+F L EGS V TC ++ P V W+++G + + ++ K + DG +L
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVY------------------PSFEASPIP 2693
+ + D Y+ N G IS S +L V +
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE 789
Query: 2694 PTFTRSIRDTFHLAENELVLE----CR----IRGQPLPKITWFKDDKQIPSDGRYQAFYL 2745
P R R F ++V CR + G P P++TW + + + D ++
Sbjct: 790 PLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 849
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
GV L ID T D+GTY C A N + + ++ +E + +P ++
Sbjct: 850 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 900
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 6/182 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLIT 2650
+P F D A EG +L C V P +TW NG VL D K + G+ +
Sbjct: 797 RPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRET-GVHS 855
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + D+ Y C N+ G S S L V E P +++ +
Sbjct: 856 LLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK-EVKKAP-VILEKLQNCGVPEGHP 913
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ LECR+ G P P W KD++ IP + R G L I D+G YT A
Sbjct: 914 VRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSA 973
Query: 2770 EN 2771
+N
Sbjct: 974 KN 975
Score = 58.0 bits (134), Expect = 6e-07
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 13/166 (7%)
Query: 3265 VAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQ 3323
+AP F L+ +++ EG + + + P V W++DG ++ + + M + DG
Sbjct: 668 IAPIFDKRLKH-FRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 726
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-----------IGTDQTSEPRIPPV 3372
L + + T+ D G YT A+N GR S SG + V G R+
Sbjct: 727 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 786
Query: 3373 VISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P P F++ P A EG ++C+V G P P++ WL
Sbjct: 787 DKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWL 832
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR---KK-----LV 2645
PVF+ L + +A EG V C V + P V WYR G L+++ +R KK
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + TL + DS ++CT N+ G +S+ A L V
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 50.4 bits (115), Expect = 1e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE--------EVVYDKRRNKYQD 3219
P FT L++ V C+V G+P PKV WY++G ++ K R+ +
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
E+ TL IA +D G + TA N G VS
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVS 250
Score = 49.6 bits (113), Expect = 2e-04
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 2694 PTFTRSIRDTFHLAENELVL-ECRIRGQPLPKITWFKDDKQIPSDGRY-------QAFYL 2745
P FT+ +++ +E +LV+ ECR++G P PK+ W+++ I + ++
Sbjct: 160 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 2746 ADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +C L I EDSG +TC A N T
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGT 248
Score = 46.4 bits (105), Expect = 0.002
Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR--PSRRAIMTLDRD-G 3322
AP F L+ L EG + V+ PS V WYR+G + P R + R
Sbjct: 159 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217
Query: 3323 QIE----LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ E L +A V D+G +TCTASN+ G S+ ++ V G + S
Sbjct: 218 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 264
Score = 44.4 bits (100), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTE------VYRNARVFVE- 2864
P F +L + + G + + ++G P+ +VEW REG + + + + R E
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + TL +++V +SG +TC A + +G V A + V DL
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD--- 3106
P F +L L G+ C VKG P P V W + G +E+ Q
Sbjct: 160 PVFTKMLQN-LSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 3107 ----CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
C L I ++ +D G ++C A+N +G S+ A+L V
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 41.9 bits (94), Expect = 0.039
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 2/119 (1%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
E +++ + PV L + EG V+L C VI P W ++ + +
Sbjct: 885 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 944
Query: 2642 KKLVD--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
D G L + A SD+ Y+ + +NE G +S +A L +Y + PP R
Sbjct: 945 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR 1003
Score = 38.3 bits (85), Expect = 0.48
Identities = 16/42 (38%), Positives = 22/42 (52%)
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+F + ++ A EG V+ EC V G P P V W R+
Sbjct: 155 PIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYRE 196
Score = 37.9 bits (84), Expect = 0.64
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 3377 DVPYSK--EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++P K P+F ++ + EG V C++VG P P VYW +D
Sbjct: 661 EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKD 706
Score = 34.3 bits (75), Expect = 7.9
Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 3083 VWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+W G E+E Q LTI + +D GRYSC A+N +G ST A + +
Sbjct: 26 MWYCEGKELENSPDIHIVQAGNLHS-LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 83
>EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform A
protein.
Length = 1896
Score = 107 bits (257), Expect = 7e-22
Identities = 107/395 (27%), Positives = 159/395 (40%), Gaps = 42/395 (10%)
Query: 3044 GLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
G G P F+ P +++++G A L C V G+P P VVW K G ++ R++ +
Sbjct: 6 GDQGSPPCFLRF-PRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASE-RLSFPAD 63
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
G + L + D G Y C A N G+A A + V+ +R +
Sbjct: 64 GAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGS 123
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV--VYDKRRNKYQDEQ 3221
G+ P F R + V V LTC+ G P P + W KDG + V+D Q +
Sbjct: 124 GEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGR 183
Query: 3222 FH-------TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCG- 3272
L I L D GVY ARN G L V + + A P+
Sbjct: 184 AEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAP 243
Query: 3273 -LEPL------YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
+EPL + ++EG + V P + W+ +G L P RR +M DRDG
Sbjct: 244 VVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV 303
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +D G+Y C A N G+ ++ ++ V EPR+
Sbjct: 304 LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV------KEPRL---------------R 342
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
F R + E RE ++EC+V P W R+
Sbjct: 343 FTRPLQDVEGREHGIAVLECKVPNSRIPTA-WFRE 376
Score = 71.7 bits (168), Expect = 4e-11
Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 23/284 (8%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR- 2751
PP F R R ++ E L+C + G+P P + W K +Q+ + R + ADG
Sbjct: 11 PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS--FPADGAEHG 68
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L + P D+G Y C+A N+ V + P + AE+ + S E
Sbjct: 69 LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAS-DPELQPAERPLPSPGSGEG- 126
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGL--- 2867
P F V RG + L G P + W ++G ++ EV+ ++ ++ G
Sbjct: 127 APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED 186
Query: 2868 ---YTLALSDVTE--TESGLYTCRAWSAHGNVDMNAAITVVQ-----PSDLDGKPAVIVG 2917
+LAL + +SG+Y C A +AHG+ A + V Q P+D D PA +V
Sbjct: 187 GPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVE 246
Query: 2918 R---PEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
K ++ G+ G+P+P+ + G P + D
Sbjct: 247 PLKCAPKTFWVNEGKHAKFRCYVMGKPEPE-IEWHWEGRPLLPD 289
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/174 (28%), Positives = 76/174 (43%), Gaps = 17/174 (9%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNG--VLLDNK-LKYRKKLVDGLITLEVLNAVPSDSAE 2663
EG K C V+ +P + W+ G +L D + L YR + DG L+VL D
Sbjct: 259 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDR--DGGFVLKVLYCQAKDRGL 316
Query: 2664 YSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C N G ++ L V P FTR ++D VLEC++ +
Sbjct: 317 YVCAARNSAGQTLSAVQLHVKEPRLR-------FTRPLQDVEGREHGIAVLECKVPNSRI 369
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSVWT 2775
P WF++D+++ +Y+ + +G V RL I +D G Y C+ V T
Sbjct: 370 P-TAWFREDQRLLPCRKYE--QIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRT 420
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/197 (26%), Positives = 80/197 (40%), Gaps = 18/197 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK------KLVDG 2647
PVF T + + G+ V LTC +PT+ W ++G+ LD + DG
Sbjct: 128 PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDG 187
Query: 2648 ---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT------- 2697
+ L +L A DS Y C N +G A L+V+ E+ P P
Sbjct: 188 PGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEP 247
Query: 2698 -RSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
+ TF + E + C + G+P P+I W + + + D R + DG L +
Sbjct: 248 LKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVL 307
Query: 2756 NPTPEDSGTYTCKAENS 2772
+D G Y C A NS
Sbjct: 308 YCQAKDRGLYVCAARNS 324
Score = 54.4 bits (125), Expect = 7e-06
Identities = 79/337 (23%), Positives = 113/337 (33%), Gaps = 34/337 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F F V G+ +L C V+ P V W + G L + L +
Sbjct: 12 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 71
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVY------PSFEAS--PIP--------PTFT 2697
A+P+D+ Y C N G +A + V P + + P+P P F
Sbjct: 72 TAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFL 131
Query: 2698 RSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR------ 2751
R + L E+VL CR G P P + W KD + F L G
Sbjct: 132 TGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGAS 191
Query: 2752 --LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L I DSG Y C A N+ Q + + SP E + L+
Sbjct: 192 LALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--HQPPESPPADPDEAPAPVVEPLK 249
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLY 2868
F V G + + G P +EW EGR + R G +
Sbjct: 250 CAPKTF-------WVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGF 302
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
L + + GLY C A ++ G + V +P
Sbjct: 303 VLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 339
Score = 53.6 bits (123), Expect = 1e-05
Identities = 78/311 (25%), Positives = 116/311 (37%), Gaps = 39/311 (12%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
++ P L + GE L+C + P VVW NG V+E G + G L I+
Sbjct: 1176 LETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEG-LELHAEGPRRVLCIQ 1233
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
G Y+C++ G S + V E ++ +A+
Sbjct: 1234 AAGPAHAGLYTCQSGAAPGAPSLSFTVQVA------EPPVRVVAPEAAQT---------- 1277
Query: 3173 RLRDRRVQATYPVRLTCQV-IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
RV++T L V + P V WYKDGE + R Q L +
Sbjct: 1278 -----RVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGAR 1332
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVV 3291
D G Y A +S + V++ + + E L PL +HEGD+ V
Sbjct: 1333 SGDAGEYLCDAPQDSRIFL----VSVEEPLLVKLVSE----LTPL-TVHEGDDATFRCEV 1383
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P VTW R+G + P + M + +I L L DAG T A G +
Sbjct: 1384 SP-PDADVTWLRNGAVVTPGPQVEMAQNGSSRI-LTLRGCQLGDAGTVTLRA----GSTA 1437
Query: 3352 TSGKVEVIGTD 3362
TS ++ V T+
Sbjct: 1438 TSARLHVRETE 1448
Score = 52.8 bits (121), Expect = 2e-05
Identities = 78/327 (23%), Positives = 127/327 (38%), Gaps = 47/327 (14%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVP-SDSAE 2663
AV RV LTC + V W ++G + + D + L VL AV DS E
Sbjct: 910 AVRLERVVLTCELCRPW-AEVRWTKDGEEVVESPALLLQKEDTVRRL-VLPAVQLEDSGE 967
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C +++E+ + + + P+ + R + +VL C + + P
Sbjct: 968 YLCEIDDESASFTVTVT--------EPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAP 1019
Query: 2724 KITWFKDDKQIPSDGRYQAFYLA-DGV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+ W+KD ++ +A L DG CRL + PED G + C A
Sbjct: 1020 -VRWYKDGLEVEES---EALVLERDGPRCRLVLPAAQPEDGGEFVCDA------------ 1063
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
G +S VTA RI + S HFG G + L+ E+ +
Sbjct: 1064 ----GDDSAFFTVTVTAPPERIVHPAARSLDLHFG---------APGRVELRCEVAPAGS 1110
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V W ++G V E ++ E TL L ++G Y C + H + N +
Sbjct: 1111 QVRWYKDGLEV-EASDALQLGAEGPTRTLTLPHAQPEDAGEYVCE--TRHEAITFNVILA 1167
Query: 2902 --VVQPSDLDGKPAVIVGRPEKDILIS 2926
VQ L+ P+ + P + +++S
Sbjct: 1168 EPPVQFLALETTPSPLCVAPGEPVVLS 1194
Score = 48.8 bits (111), Expect = 3e-04
Identities = 66/296 (22%), Positives = 113/296 (38%), Gaps = 38/296 (12%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
V L C +S D V WY++G+ ++ + L + A P D E+ C +
Sbjct: 1007 VVLMCE-LSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGD 1065
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKD 2730
++ + + P P RS+ D A + L C + ++ W+KD
Sbjct: 1066 DSAFFTVTVTAP--PERIVHPA----ARSL-DLHFGAPGRVELRCEVAPAG-SQVRWYKD 1117
Query: 2731 DKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
++ + Q A+G R L + + PED+G Y C+ R
Sbjct: 1118 GLEVEASDALQLG--AEGPTRTLTLPHAQPEDAGEYVCET-----------------RHE 1158
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREG 2849
++ NV+ AE + +LE+ + VA G + L E+ V W G
Sbjct: 1159 AITFNVILAEPP-VQFLALETTP-------SPLCVAPGEPVVLSCELSRAGAPVVWSHNG 1210
Query: 2850 RSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
R V E + E L + +GLYTC++ +A G ++ + V +P
Sbjct: 1211 RPVQEG-EGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEP 1265
Score = 46.8 bits (106), Expect = 0.001
Identities = 69/285 (24%), Positives = 111/285 (38%), Gaps = 39/285 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+ E L C V + P V W K+G EVEE + + + G L + D G +
Sbjct: 820 ITSECVMLACEVDREDAP-VRWYKDGQEVEE-SDFVVLENEGPHRRLVLPATQPSDGGEF 877
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A G Y + + TD + W S +V + +R RV
Sbjct: 878 QCVA----GDECAYFTVTI-TDVSSWIVYP------SGKV-------YVAAVRLERVV-- 917
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
LTC++ P +V W KDGEEVV +++ L + L+D G Y
Sbjct: 918 ----LTCELC-RPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEI 972
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+ S + + V + +R + P + + + E + + V WY
Sbjct: 973 DDESASFTV---TVTEPPVRI-IYPR-----DEVTLIAVTLECVVLMCELSREDAPVRWY 1023
Query: 3303 RDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNE 3346
+DG+ + S + L+RDG + L L A D G + C A ++
Sbjct: 1024 KDGLEVEESE--ALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDD 1066
Score = 37.9 bits (84), Expect = 0.64
Identities = 40/168 (23%), Positives = 68/168 (40%), Gaps = 13/168 (7%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV-PSDSAE 2663
A+ V L C V D V WY++G ++ + +G VL A PSD E
Sbjct: 819 AITSECVMLACEV-DREDAPVRWYKDGQEVEES-DFVVLENEGPHRRLVLPATQPSDGGE 876
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
+ C +E + + + S+ P + ++R +VL C + +P
Sbjct: 877 FQCVAGDECAYFTVT--ITDVSSWIVYPSGKVYVAAVR------LERVVLTCELC-RPWA 927
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
++ W KD +++ D V RL + EDSG Y C+ ++
Sbjct: 928 EVRWTKDGEEVVESPAL-LLQKEDTVRRLVLPAVQLEDSGEYLCEIDD 974
Score = 36.7 bits (81), Expect = 1.5
Identities = 41/162 (25%), Positives = 61/162 (37%), Gaps = 6/162 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G V L+C + + P V W NG + L + A P+ + Y+C
Sbjct: 1188 GEPVVLSCELSRAGAPVV-WSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQ 1246
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
GA S S ++V P +R T + ELV+ G P + W
Sbjct: 1247 SGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPG-GDLELVVHLSGPGGP---VRW 1302
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+KD +++ S GR Q A L + D+G Y C A
Sbjct: 1303 YKDGERLASQGRVQ-LEQAGARQVLRVQGARSGDAGEYLCDA 1343
Score = 36.3 bits (80), Expect = 1.9
Identities = 45/174 (25%), Positives = 65/174 (37%), Gaps = 15/174 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T EG C V S D VTW RNG ++ + L +
Sbjct: 1366 LTPLTVHEGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLG 1424
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI-R 2718
D+ TV G+ +TSA L V + F R ++D ++ LE R
Sbjct: 1425 DAG----TVTLRAGSTATSARLHVRET------ELLFLRRLQDVRAEEGQDVCLEVETGR 1474
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAEN 2771
+ W + + +P D R DG + RL I D GTY C++ +
Sbjct: 1475 VGAAGAVRWVRGGQPLPHDSRLS--MAQDGHIHRLFIHGVILADQGTYGCESHH 1526
Score = 34.7 bits (76), Expect = 5.9
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Query: 2671 ENGAIS-TSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFK 2729
++G +S T+ +L+ +P T R D + EC + Q L +TW K
Sbjct: 1605 DSGCVSFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECEL-SQALADVTWEK 1663
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLA-IDNPTPEDSGTYTC 2767
D + R + L G RL + P D+GTY+C
Sbjct: 1664 DGNALTPSPRLRLQAL--GTRRLLQLRRCGPSDAGTYSC 1700
>EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform C
protein.
Length = 1544
Score = 107 bits (257), Expect = 7e-22
Identities = 107/395 (27%), Positives = 159/395 (40%), Gaps = 42/395 (10%)
Query: 3044 GLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
G G P F+ P +++++G A L C V G+P P VVW K G ++ R++ +
Sbjct: 6 GDQGSPPCFLRF-PRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASE-RLSFPAD 63
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
G + L + D G Y C A N G+A A + V+ +R +
Sbjct: 64 GAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGS 123
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV--VYDKRRNKYQDEQ 3221
G+ P F R + V V LTC+ G P P + W KDG + V+D Q +
Sbjct: 124 GEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGR 183
Query: 3222 FH-------TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCG- 3272
L I L D GVY ARN G L V + + A P+
Sbjct: 184 AEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAP 243
Query: 3273 -LEPL------YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
+EPL + ++EG + V P + W+ +G L P RR +M DRDG
Sbjct: 244 VVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV 303
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +D G+Y C A N G+ ++ ++ V EPR+
Sbjct: 304 LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV------KEPRL---------------R 342
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
F R + E RE ++EC+V P W R+
Sbjct: 343 FTRPLQDVEGREHGIAVLECKVPNSRIPTA-WFRE 376
Score = 71.7 bits (168), Expect = 4e-11
Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 23/284 (8%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR- 2751
PP F R R ++ E L+C + G+P P + W K +Q+ + R + ADG
Sbjct: 11 PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS--FPADGAEHG 68
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L + P D+G Y C+A N+ V + P + AE+ + S E
Sbjct: 69 LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAS-DPELQPAERPLPSPGSGEG- 126
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGL--- 2867
P F V RG + L G P + W ++G ++ EV+ ++ ++ G
Sbjct: 127 APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED 186
Query: 2868 ---YTLALSDVTE--TESGLYTCRAWSAHGNVDMNAAITVVQ-----PSDLDGKPAVIVG 2917
+LAL + +SG+Y C A +AHG+ A + V Q P+D D PA +V
Sbjct: 187 GPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVE 246
Query: 2918 R---PEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
K ++ G+ G+P+P+ + G P + D
Sbjct: 247 PLKCAPKTFWVNEGKHAKFRCYVMGKPEPE-IEWHWEGRPLLPD 289
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/174 (28%), Positives = 76/174 (43%), Gaps = 17/174 (9%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNG--VLLDNK-LKYRKKLVDGLITLEVLNAVPSDSAE 2663
EG K C V+ +P + W+ G +L D + L YR + DG L+VL D
Sbjct: 259 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDR--DGGFVLKVLYCQAKDRGL 316
Query: 2664 YSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C N G ++ L V P FTR ++D VLEC++ +
Sbjct: 317 YVCAARNSAGQTLSAVQLHVKEPRLR-------FTRPLQDVEGREHGIAVLECKVPNSRI 369
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSVWT 2775
P WF++D+++ +Y+ + +G V RL I +D G Y C+ V T
Sbjct: 370 P-TAWFREDQRLLPCRKYE--QIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRT 420
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/197 (26%), Positives = 80/197 (40%), Gaps = 18/197 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK------KLVDG 2647
PVF T + + G+ V LTC +PT+ W ++G+ LD + DG
Sbjct: 128 PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDG 187
Query: 2648 ---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT------- 2697
+ L +L A DS Y C N +G A L+V+ E+ P P
Sbjct: 188 PGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEP 247
Query: 2698 -RSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
+ TF + E + C + G+P P+I W + + + D R + DG L +
Sbjct: 248 LKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVL 307
Query: 2756 NPTPEDSGTYTCKAENS 2772
+D G Y C A NS
Sbjct: 308 YCQAKDRGLYVCAARNS 324
Score = 54.4 bits (125), Expect = 7e-06
Identities = 79/337 (23%), Positives = 113/337 (33%), Gaps = 34/337 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F F V G+ +L C V+ P V W + G L + L +
Sbjct: 12 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 71
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVY------PSFEAS--PIP--------PTFT 2697
A+P+D+ Y C N G +A + V P + + P+P P F
Sbjct: 72 TAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFL 131
Query: 2698 RSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR------ 2751
R + L E+VL CR G P P + W KD + F L G
Sbjct: 132 TGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGAS 191
Query: 2752 --LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L I DSG Y C A N+ Q + + SP E + L+
Sbjct: 192 LALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--HQPPESPPADPDEAPAPVVEPLK 249
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLY 2868
F V G + + G P +EW EGR + R G +
Sbjct: 250 CAPKTF-------WVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGF 302
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
L + + GLY C A ++ G + V +P
Sbjct: 303 VLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 339
Score = 53.6 bits (123), Expect = 1e-05
Identities = 78/311 (25%), Positives = 116/311 (37%), Gaps = 39/311 (12%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
++ P L + GE L+C + P VVW NG V+E G + G L I+
Sbjct: 1177 LETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEG-LELHAEGPRRVLCIQ 1234
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
G Y+C++ G S + V E ++ +A+
Sbjct: 1235 AAGPAHAGLYTCQSGAAPGAPSLSFTVQVA------EPPVRVVAPEAAQT---------- 1278
Query: 3173 RLRDRRVQATYPVRLTCQV-IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
RV++T L V + P V WYKDGE + R Q L +
Sbjct: 1279 -----RVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGAR 1333
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVV 3291
D G Y A +S + V++ + + E L PL +HEGD+ V
Sbjct: 1334 SGDAGEYLCDAPQDSRIFL----VSVEEPLLVKLVSE----LTPL-TVHEGDDATFRCEV 1384
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P VTW R+G + P + M + +I L L DAG T A G +
Sbjct: 1385 SP-PDADVTWLRNGAVVTPGPQVEMAQNGSSRI-LTLRGCQLGDAGTVTLRA----GSTA 1438
Query: 3352 TSGKVEVIGTD 3362
TS ++ V T+
Sbjct: 1439 TSARLHVRETE 1449
Score = 52.8 bits (121), Expect = 2e-05
Identities = 78/327 (23%), Positives = 127/327 (38%), Gaps = 47/327 (14%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVP-SDSAE 2663
AV RV LTC + V W ++G + + D + L VL AV DS E
Sbjct: 911 AVRLERVVLTCELCRPW-AEVRWTKDGEEVVESPALLLQKEDTVRRL-VLPAVQLEDSGE 968
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C +++E+ + + + P+ + R + +VL C + + P
Sbjct: 969 YLCEIDDESASFTVTVT--------EPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAP 1020
Query: 2724 KITWFKDDKQIPSDGRYQAFYLA-DGV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+ W+KD ++ +A L DG CRL + PED G + C A
Sbjct: 1021 -VRWYKDGLEVEES---EALVLERDGPRCRLVLPAAQPEDGGEFVCDA------------ 1064
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
G +S VTA RI + S HFG G + L+ E+ +
Sbjct: 1065 ----GDDSAFFTVTVTAPPERIVHPAARSLDLHFG---------APGRVELRCEVAPAGS 1111
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V W ++G V E ++ E TL L ++G Y C + H + N +
Sbjct: 1112 QVRWYKDGLEV-EASDALQLGAEGPTRTLTLPHAQPEDAGEYVCE--TRHEAITFNVILA 1168
Query: 2902 --VVQPSDLDGKPAVIVGRPEKDILIS 2926
VQ L+ P+ + P + +++S
Sbjct: 1169 EPPVQFLALETTPSPLCVAPGEPVVLS 1195
Score = 48.8 bits (111), Expect = 3e-04
Identities = 66/296 (22%), Positives = 113/296 (38%), Gaps = 38/296 (12%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
V L C +S D V WY++G+ ++ + L + A P D E+ C +
Sbjct: 1008 VVLMCE-LSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGD 1066
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKD 2730
++ + + P P RS+ D A + L C + ++ W+KD
Sbjct: 1067 DSAFFTVTVTAP--PERIVHPA----ARSL-DLHFGAPGRVELRCEVAPAG-SQVRWYKD 1118
Query: 2731 DKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
++ + Q A+G R L + + PED+G Y C+ R
Sbjct: 1119 GLEVEASDALQLG--AEGPTRTLTLPHAQPEDAGEYVCET-----------------RHE 1159
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREG 2849
++ NV+ AE + +LE+ + VA G + L E+ V W G
Sbjct: 1160 AITFNVILAEPP-VQFLALETTP-------SPLCVAPGEPVVLSCELSRAGAPVVWSHNG 1211
Query: 2850 RSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
R V E + E L + +GLYTC++ +A G ++ + V +P
Sbjct: 1212 RPVQEG-EGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEP 1266
Score = 46.8 bits (106), Expect = 0.001
Identities = 69/285 (24%), Positives = 111/285 (38%), Gaps = 39/285 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+ E L C V + P V W K+G EVEE + + + G L + D G +
Sbjct: 821 ITSECVMLACEVDREDAP-VRWYKDGQEVEE-SDFVVLENEGPHRRLVLPATQPSDGGEF 878
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A G Y + + TD + W S +V + +R RV
Sbjct: 879 QCVA----GDECAYFTVTI-TDVSSWIVYP------SGKV-------YVAAVRLERVV-- 918
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
LTC++ P +V W KDGEEVV +++ L + L+D G Y
Sbjct: 919 ----LTCELC-RPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEI 973
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+ S + + V + +R + P + + + E + + V WY
Sbjct: 974 DDESASFTV---TVTEPPVRI-IYPR-----DEVTLIAVTLECVVLMCELSREDAPVRWY 1024
Query: 3303 RDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNE 3346
+DG+ + S + L+RDG + L L A D G + C A ++
Sbjct: 1025 KDGLEVEESE--ALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDD 1067
Score = 37.9 bits (84), Expect = 0.64
Identities = 40/168 (23%), Positives = 68/168 (40%), Gaps = 13/168 (7%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV-PSDSAE 2663
A+ V L C V D V WY++G ++ + +G VL A PSD E
Sbjct: 820 AITSECVMLACEV-DREDAPVRWYKDGQEVEES-DFVVLENEGPHRRLVLPATQPSDGGE 877
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
+ C +E + + + S+ P + ++R +VL C + +P
Sbjct: 878 FQCVAGDECAYFTVT--ITDVSSWIVYPSGKVYVAAVR------LERVVLTCELC-RPWA 928
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
++ W KD +++ D V RL + EDSG Y C+ ++
Sbjct: 929 EVRWTKDGEEVVESPAL-LLQKEDTVRRLVLPAVQLEDSGEYLCEIDD 975
Score = 36.7 bits (81), Expect = 1.5
Identities = 41/162 (25%), Positives = 61/162 (37%), Gaps = 6/162 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G V L+C + + P V W NG + L + A P+ + Y+C
Sbjct: 1189 GEPVVLSCELSRAGAPVV-WSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQ 1247
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
GA S S ++V P +R T + ELV+ G P + W
Sbjct: 1248 SGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPG-GDLELVVHLSGPGGP---VRW 1303
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+KD +++ S GR Q A L + D+G Y C A
Sbjct: 1304 YKDGERLASQGRVQ-LEQAGARQVLRVQGARSGDAGEYLCDA 1344
Score = 36.3 bits (80), Expect = 1.9
Identities = 45/174 (25%), Positives = 65/174 (37%), Gaps = 15/174 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T EG C V S D VTW RNG ++ + L +
Sbjct: 1367 LTPLTVHEGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLG 1425
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI-R 2718
D+ TV G+ +TSA L V + F R ++D ++ LE R
Sbjct: 1426 DAG----TVTLRAGSTATSARLHVRET------ELLFLRRLQDVRAEEGQDVCLEVETGR 1475
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAEN 2771
+ W + + +P D R DG + RL I D GTY C++ +
Sbjct: 1476 VGAAGAVRWVRGGQPLPHDSRLS--MAQDGHIHRLFIHGVILADQGTYGCESHH 1527
>BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein.
Length = 1044
Score = 107 bits (257), Expect = 7e-22
Identities = 107/395 (27%), Positives = 159/395 (40%), Gaps = 42/395 (10%)
Query: 3044 GLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
G G P F+ P +++++G A L C V G+P P VVW K G ++ R++ +
Sbjct: 25 GDQGSPPCFLRF-PRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASE-RLSFPAD 82
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
G + L + D G Y C A N G+A A + V+ +R +
Sbjct: 83 GAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGS 142
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV--VYDKRRNKYQDEQ 3221
G+ P F R + V V LTC+ G P P + W KDG + V+D Q +
Sbjct: 143 GEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGR 202
Query: 3222 FH-------TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCG- 3272
L I L D GVY ARN G L V + + A P+
Sbjct: 203 AEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAP 262
Query: 3273 -LEPL------YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
+EPL + ++EG + V P + W+ +G L P RR +M DRDG
Sbjct: 263 VVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV 322
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +D G+Y C A N G+ ++ ++ V EPR+
Sbjct: 323 LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV------KEPRL---------------R 361
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
F R + E RE ++EC+V P W R+
Sbjct: 362 FTRPLQDVEGREHGIAVLECKVPNSRIPTA-WFRE 395
Score = 71.7 bits (168), Expect = 4e-11
Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 23/284 (8%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR- 2751
PP F R R ++ E L+C + G+P P + W K +Q+ + R + ADG
Sbjct: 30 PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS--FPADGAEHG 87
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L + P D+G Y C+A N+ V + P + AE+ + S E
Sbjct: 88 LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAS-DPELQPAERPLPSPGSGEG- 145
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGL--- 2867
P F V RG + L G P + W ++G ++ EV+ ++ ++ G
Sbjct: 146 APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED 205
Query: 2868 ---YTLALSDVTE--TESGLYTCRAWSAHGNVDMNAAITVVQ-----PSDLDGKPAVIVG 2917
+LAL + +SG+Y C A +AHG+ A + V Q P+D D PA +V
Sbjct: 206 GPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVE 265
Query: 2918 R---PEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
K ++ G+ G+P+P+ + G P + D
Sbjct: 266 PLKCAPKTFWVNEGKHAKFRCYVMGKPEPE-IEWHWEGRPLLPD 308
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/174 (28%), Positives = 76/174 (43%), Gaps = 17/174 (9%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNG--VLLDNK-LKYRKKLVDGLITLEVLNAVPSDSAE 2663
EG K C V+ +P + W+ G +L D + L YR + DG L+VL D
Sbjct: 278 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDR--DGGFVLKVLYCQAKDRGL 335
Query: 2664 YSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C N G ++ L V P FTR ++D VLEC++ +
Sbjct: 336 YVCAARNSAGQTLSAVQLHVKEPRLR-------FTRPLQDVEGREHGIAVLECKVPNSRI 388
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSVWT 2775
P WF++D+++ +Y+ + +G V RL I +D G Y C+ V T
Sbjct: 389 P-TAWFREDQRLLPCRKYE--QIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRT 439
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/197 (26%), Positives = 80/197 (40%), Gaps = 18/197 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK------KLVDG 2647
PVF T + + G+ V LTC +PT+ W ++G+ LD + DG
Sbjct: 147 PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDG 206
Query: 2648 ---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT------- 2697
+ L +L A DS Y C N +G A L+V+ E+ P P
Sbjct: 207 PGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEP 266
Query: 2698 -RSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
+ TF + E + C + G+P P+I W + + + D R + DG L +
Sbjct: 267 LKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVL 326
Query: 2756 NPTPEDSGTYTCKAENS 2772
+D G Y C A NS
Sbjct: 327 YCQAKDRGLYVCAARNS 343
Score = 54.4 bits (125), Expect = 7e-06
Identities = 79/337 (23%), Positives = 113/337 (33%), Gaps = 34/337 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F F V G+ +L C V+ P V W + G L + L +
Sbjct: 31 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 90
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVY------PSFEAS--PIP--------PTFT 2697
A+P+D+ Y C N G +A + V P + + P+P P F
Sbjct: 91 TAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFL 150
Query: 2698 RSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR------ 2751
R + L E+VL CR G P P + W KD + F L G
Sbjct: 151 TGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGAS 210
Query: 2752 --LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L I DSG Y C A N+ Q + + SP E + L+
Sbjct: 211 LALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--HQPPESPPADPDEAPAPVVEPLK 268
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLY 2868
F V G + + G P +EW EGR + R G +
Sbjct: 269 CAPKTF-------WVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGF 321
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
L + + GLY C A ++ G + V +P
Sbjct: 322 VLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 358
Score = 39.1 bits (87), Expect = 0.28
Identities = 42/186 (22%), Positives = 76/186 (40%), Gaps = 13/186 (6%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV-PSDSAE 2663
A+ V L C V D V WY++G ++ + +G VL A PSD E
Sbjct: 838 AITSECVMLACEV-DREDAPVRWYKDGQEVEES-DFVVLENEGPHRRLVLPATQPSDGGE 895
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
+ C +E + + + S+ P + ++R +VL C + +P
Sbjct: 896 FQCVAGDECAYFTVT--ITDVSSWIVYPSGKVYVAAVR------LERVVLTCELC-RPWA 946
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++ W KD +++ D V RL + EDSG Y C+ ++ + +T +
Sbjct: 947 EVRWTKDGEEVVESPAL-LLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTES 1005
Query: 2784 FTGRES 2789
+ ++S
Sbjct: 1006 YQSQDS 1011
>AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform
protein.
Length = 2154
Score = 105 bits (253), Expect = 2e-21
Identities = 89/331 (26%), Positives = 139/331 (41%), Gaps = 17/331 (5%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKK 2643
TL N+ P L T G + C+VIS P ++WY+ LL K K
Sbjct: 786 TLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLSTGFKC-KF 843
Query: 2644 LVDGL-ITLEVLNAVPSDSAEYSCTVENENGAISTSANLK------VYPSFEASPIPPTF 2696
L DG TL ++ A P D+A Y+C +N+ G +TSA+L V P E PP
Sbjct: 844 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAI 903
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
++DT +CR+ G L K++W+ DK+I R+ + +L I
Sbjct: 904 ITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAE 961
Query: 2757 PTPEDSGTYTCKAENSVWTDQIT---HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
PED GTYT A N+V T F+ E S + + ++ ++P
Sbjct: 962 AYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKP 1021
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQ-GLYTLA 2871
F L+ +V G T+ + G P ++W + + F E G+ +
Sbjct: 1022 SFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALML 1081
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ D +G Y+C+A ++ G A +TV
Sbjct: 1082 IVDAYSEHAGQYSCKAANSAGEATCAATLTV 1112
Score = 97.9 bits (233), Expect = 6e-19
Identities = 79/274 (28%), Positives = 122/274 (44%), Gaps = 20/274 (7%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDE 3220
V PPQ L+ VQ+ P R + G P PK+SWYK+ E+++ + K+ D
Sbjct: 789 VNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDG 847
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP---LY 3277
Q +TL + +D VY A+N+ G + L V+ + V+P+ + P +
Sbjct: 848 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE--VPEVVSPDQEMPVYPPAIIT 905
Query: 3278 KLH-----EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L EG R V + V+WY +++PSR MT D +L +A
Sbjct: 906 PLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAY 963
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE-PRIPPVVISPDVPYSKEPM-----F 3386
D G YT ASN VG+ S++ + + G + E +S V + KEP+ F
Sbjct: 964 PEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSF 1023
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
I+ S G+TV V G PKP++ W +
Sbjct: 1024 IQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHN 1057
Score = 85.0 bits (201), Expect = 4e-15
Identities = 75/319 (23%), Positives = 130/319 (40%), Gaps = 34/319 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ +G+ A + G+P P + W K ++ + +G + L + + +D
Sbjct: 806 VQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 864
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+CEA N +G A+T A L+V E + ++ V YPP L+D
Sbjct: 865 YTCEAKNDYGVATTSASLSV-------EVPEVVSPDQEMPV---YPPAIITPLQDTVTSE 914
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P R C+V G+ KVSWY +++ + Q E + LEIA +D G Y
Sbjct: 915 GQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 973
Query: 3242 ARNNSGAVSCHCGLVVD---------KGIRAYVAPEFCCGLEPL------------YKLH 3280
A N G VS L ++ + +V+ EPL ++H
Sbjct: 974 ASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVH 1033
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD-GQIELALAAVTTRDAGVY 3339
G+ +R A V P + W+ + + P++ + + G + + + AG Y
Sbjct: 1034 NGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQY 1093
Query: 3340 TCTASNEVGRASTSGKVEV 3358
+C A+N G A+ + + V
Sbjct: 1094 SCKAANSAGEATCAATLTV 1112
Score = 83.0 bits (196), Expect = 2e-14
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F +++ G L+ +VI P + W+ NGVLL Y+ +L +
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEA------------------SPIPPT 2695
L D EY+C N+ G SA LK+ E P PP
Sbjct: 1244 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 1303
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
F + ++ + E + G+P P +TWFK++KQ+ + Y + +G ++
Sbjct: 1304 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 1363
Query: 2756 NPTPEDSGTYTCKAEN 2771
+P EDSG Y CKAEN
Sbjct: 1364 DPQREDSGLYICKAEN 1379
Score = 74.1 bits (174), Expect = 8e-12
Identities = 60/229 (26%), Positives = 94/229 (41%), Gaps = 7/229 (3%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
ES S+ G P F+ + I G+ A L+ +V G P P + W NG +
Sbjct: 1167 ESPVYSTKFDSEKEGTGPIFIKEV-SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLT 1225
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
A F+G D L I ++DEG Y+C A+N +GK A L + + D
Sbjct: 1226 PSAD-YKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-NSKGEGHKDT 1283
Query: 3153 KLKRERSAEVE---GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVV 3209
+ + + +E G PP F L+ R P V+G P P V+W+K+ +++
Sbjct: 1284 ETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLC 1343
Query: 3210 YDKRRN-KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ T + +D G+Y A N G +C L+V
Sbjct: 1344 TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 1392
Score = 60.9 bits (141), Expect = 8e-08
Identities = 52/176 (29%), Positives = 84/176 (47%), Gaps = 11/176 (6%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG-GVYEVTAR 3243
V LT + + +V+WY + + V D++ QD+ +TL I N +D G Y A
Sbjct: 1987 VHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 2044
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+SG + L V K RA AP +EPL ++ G + + +++ P+V W++
Sbjct: 2045 NDSGKTATSAKLTVVK--RA--APVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFK 2099
Query: 3304 DGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G + S + +I + +E+ V D G YTC ASNE G S + + V
Sbjct: 2100 AGREIYESDKCSIRSSKYISSLEILRTQVV--DCGEYTCKASNEYGSVSCTATLTV 2153
Score = 59.3 bits (137), Expect = 2e-07
Identities = 50/180 (27%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+ T L D + EG V LT S+ ++ + V WY L+ + K++ TL +
Sbjct: 1970 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 2027
Query: 2654 LNAVPSD-SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENEL 2711
D EY C N++G +TSA L V A+P+ + HLA+
Sbjct: 2028 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK--RAAPVIKRKIEPLEVALGHLAK--- 2082
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C I+ P + WFK ++I + + + + L I D G YTCKA N
Sbjct: 2083 -FTCEIQSAPNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKASN 2140
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 22/150 (14%)
Query: 3109 LTIKDINIDD-EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I +N +D +G Y CEA N GK +T A+L VV +R+A
Sbjct: 2025 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV--------------KRAA------- 2063
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P ++ V + + TC++ +P + W+K G E+ + + + +LEI
Sbjct: 2064 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 2123
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
T + D G Y A N G+VSC L V
Sbjct: 2124 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153
Score = 56.8 bits (131), Expect = 1e-06
Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD +S V P + W+ +GV L PS D D L + D G YTC
Sbjct: 1198 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTC 1256
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM---FIRKPRSSEAREG 3398
ASN+ G+ S +++ + + ++ + P F+++ + +G
Sbjct: 1257 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 1316
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
I E VVG+P P V W ++
Sbjct: 1317 LPAIFEYTVVGEPAPTVTWFKE 1338
Score = 54.8 bits (126), Expect = 5e-06
Identities = 50/230 (21%), Positives = 86/230 (37%), Gaps = 5/230 (2%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P F + + + + L + G P PKI WF + + Y+ + D +
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
+ ED G YTC A N + ++ + + + + P
Sbjct: 1244 LFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 1302
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLA 2871
HF L + A+G + + G P V W +E + + T VY + G T
Sbjct: 1303 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTI-IHNPNGSGTFI 1361
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPE 2920
++D +SGLY C+A + G A + V ++ +D+ P PE
Sbjct: 1362 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPE 1411
Score = 53.6 bits (123), Expect = 1e-05
Identities = 56/229 (24%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+E EG P F + + + L+ VIG P PK+ W+ +G + D
Sbjct: 1177 SEKEGT-GPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 1235
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--------DKGIRAYVA----- 3266
H+L I T L+D G Y A N+ G C L + D + VA
Sbjct: 1236 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 1295
Query: 3267 ------PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR 3320
P F L+P+ + +G V P+ VTW+++ +L S + +
Sbjct: 1296 LGGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 1354
Query: 3321 DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI--GTDQTSEP 3367
+G + D+G+Y C A N +G ++ + ++ V+ TD T P
Sbjct: 1355 NGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 1403
Score = 47.2 bits (107), Expect = 0.001
Identities = 43/183 (23%), Positives = 75/183 (40%), Gaps = 31/183 (16%)
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED-SGTYTCKAENSVWTDQITHFV 2782
++ W+ ++K +PSD +++ L ID ED G Y C+A N
Sbjct: 1998 EVNWYFENKLVPSDEKFKCLQ-DQNTYTLVIDKVNTEDHQGEYVCEALND---------- 2046
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
S T+ K + +++ P + +VA G EI+ P
Sbjct: 2047 ---------SGKTATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEIQSAPNV 2093
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLY--TLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
R +W + GR E+Y + + + Y +L + + G YTC+A + +G+V A
Sbjct: 2094 RFQWFKAGR---EIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 2150
Query: 2900 ITV 2902
+TV
Sbjct: 2151 LTV 2153
Score = 45.6 bits (103), Expect = 0.003
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L++ G A TC ++ P W K G E+ E+ + + + + + L I + D
Sbjct: 2073 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCSIRSSKYISSLEILRTQVVDC 2131
Query: 3120 GRYSCEATNTHGKASTYARLAV 3141
G Y+C+A+N +G S A L V
Sbjct: 2132 GEYTCKASNEYGSVSCTATLTV 2153
Score = 43.6 bits (98), Expect = 0.013
Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 2/107 (1%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
++ S K T+ + + PV + G K TC + S+ + W++ G +
Sbjct: 2049 KTATSAKLTVVKRAA--PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE 2106
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
K + + +LE+L D EY+C NE G++S +A L V
Sbjct: 2107 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153
Score = 43.2 bits (97), Expect = 0.017
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query: 3047 GDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV--EEEAGRMTSQFNG 3104
G +P F+ L L++ GET V G P P + W N + ++ + G
Sbjct: 1018 GQKPSFIQPL-SSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTG 1076
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L + D + G+YSC+A N+ G+A+ A L V
Sbjct: 1077 MALMLIV-DAYSEHAGQYSCKAANSAGEATCAATLTV 1112
Score = 40.7 bits (91), Expect = 0.090
Identities = 46/185 (24%), Positives = 76/185 (41%), Gaps = 20/185 (10%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLN 2655
T L D +EG++ L C V +V WY N + D+++ + +V G V+N
Sbjct: 5 TPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVIN 61
Query: 2656 AV-PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
SD Y V G + T+ NL V E I R +RD +V E
Sbjct: 62 RTHASDEGPYKLIV----GRVETNCNLSV----EKIKI----IRGLRDLTCTETQNVVFE 109
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
+ + + W DK+I +Y+ + +L + N +D G YT A ++
Sbjct: 110 VELSHSGI-DVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEGKYTFYAGENIT 167
Query: 2775 TDQIT 2779
+ ++T
Sbjct: 168 SGKLT 172
Score = 40.3 bits (90), Expect = 0.12
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 21/187 (11%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L + T E T + + V W +NGV+L++ KY + + +L + N
Sbjct: 269 LKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIV 328
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D + Y + G + SA L V E I + +D L + E +
Sbjct: 329 DESVYGFRL----GRLGASARLHV----ETVKI----IKKPKDVTALENATVAFEVSVSH 376
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT-------CKAENS 2772
+P + WF + +I +++ V +L + N +P D+G YT CKA+
Sbjct: 377 DTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLF 434
Query: 2773 VWTDQIT 2779
V T IT
Sbjct: 435 VETLHIT 441
Score = 39.1 bits (87), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+F ++D +V C+V P V W KD +E+ R +++ H L I
Sbjct: 615 EFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIP 673
Query: 3229 PTNLDDGGVYEVTARNN 3245
T + D G Y V A N
Sbjct: 674 STRMSDAGKYTVVAGGN 690
Score = 39.1 bits (87), Expect = 0.28
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L ++ G A +V G+P P V W K ++
Sbjct: 1302 PHFLKELK-PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 1360
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
+ D +D G Y C+A N G+++ A L V+ + T D K + + E D+P
Sbjct: 1361 IVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM-TDTPCKAKSTPEAPEDFP 1417
Score = 36.7 bits (81), Expect = 1.5
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRD-AGVYTCTASNEVGRASTSGKVE 3357
V WY + +L PS L L + V T D G Y C A N+ G+ +TS K+
Sbjct: 1999 VNWYFEN-KLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 2057
Query: 3358 VI 3359
V+
Sbjct: 2058 VV 2059
Score = 35.5 bits (78), Expect = 3.4
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERS 3159
+G D KD I +Y EA HGK L ++ D + + A + +
Sbjct: 115 SGIDVLWNFKDKEIKPSSKYKIEA---HGKIYKLTVLNMMKDDEGKYTFYAGENITSGKL 171
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
G + L D+ V + C+V +P K W +DG+ + D
Sbjct: 172 TVAGG----AISKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESD 226
Query: 3220 EQFHTLEIAPTNLDDGGVY 3238
L IA T LDD G Y
Sbjct: 227 GHKRRLIIAATKLDDIGEY 245
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 103 bits (246), Expect = 1e-20
Identities = 81/267 (30%), Positives = 109/267 (40%), Gaps = 16/267 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+F R + V L+CQ++G+P P+VSW KD + V R QD + L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD-KGIRAYVAPEFCCGLEPL-YKLHEGDEL 3285
L D G Y ARN G GL VD + A AP F L P ++ EG E
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFL--LRPTSIRVREGSEA 127
Query: 3286 RISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
V P V+W +DG RL P + + L + A RD G Y A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 3345 NEVGRASTSGK--VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR----KPRSSEAR-- 3396
N +G AS + V+ D S P + + +E M P S+ R
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTC 247
Query: 3397 ---EGDTVIIECEVVGDPKPDVYWLRD 3420
EG + C V G+PKP+ W +D
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKD 274
Score = 102 bits (244), Expect = 3e-20
Identities = 142/607 (23%), Positives = 224/607 (36%), Gaps = 61/607 (10%)
Query: 2802 RIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNAR 2860
++ ++ + P F + D + G + L+ + R WL++G +T+ +
Sbjct: 4887 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 4946
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPE 2920
+ G +L ++ + ++G YTC+ + G V +A V+V E
Sbjct: 4947 DQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSAC--------------VVVSGSE 4992
Query: 2921 KDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVL 2980
+ S G +++ +FR + + P E V ++S ++P+ A
Sbjct: 4993 SEAESSSGGELDDAFRRAARRLHRLFRTKSPAE---VSDEELFLSADEGPAEPEEPADWQ 5049
Query: 2981 AYKVESWLIGAEGGARW-VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
Y+ + I A +T A L G E R S +T +
Sbjct: 5050 TYREDEHFICIRFEALTEARQAVTRFQEMFA-TLGIGVEIKLVEQGPRRVEMCISKETPA 5108
Query: 3040 SIGVG------LAGDR-PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
+ L D P F+ L Q ++ G + C V G+P+P V W K+G +E
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQ-EVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE 5167
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--A 3150
E+ M ++ L I + D G Y C A N+ G +ST A L V T ++ A
Sbjct: 5168 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAA 5227
Query: 3151 DAKLKRE--------RSAEVEGDYP-------PQFTMRLRDRRV-QATYPVRLTCQVIGS 3194
DA S E EG PQ LRD +V T + +V G
Sbjct: 5228 DATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY 5287
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
P P++ W+KDG+ + + HTLEI +D G Y N GA
Sbjct: 5288 PAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSAR 5347
Query: 3255 LVV----------DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
L+V + + P K+ +G + S VE P V W R+
Sbjct: 5348 LLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLRE 5407
Query: 3305 ----GVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
GV + P Q L L V + G YTC ASN G+A S + V
Sbjct: 5408 EAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS 5467
Query: 3360 GTDQTSE 3366
G + E
Sbjct: 5468 GLPKVEE 5474
Score = 85.4 bits (202), Expect = 3e-15
Identities = 91/309 (29%), Positives = 127/309 (41%), Gaps = 23/309 (7%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNG 3104
A P F+ + P +++ G A C V G P P V W K+G + E G R+ + G
Sbjct: 106 AEQAPHFL-LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELG 164
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEAD---------AKLK 3155
L I+ D G Y A N G AS A L V +D + A L+
Sbjct: 165 EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224
Query: 3156 RERSA-EVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR 3214
R R A EG + R V RL+C V G P P+ W KDG+ V +R
Sbjct: 225 RRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRH 284
Query: 3215 NKYQDEQFH-TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
Y+D Q + L+I D G+Y TA N G LVV +R P F L
Sbjct: 285 VVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVV---VREPAVP-FKKRL 339
Query: 3274 EPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVT 3332
+ L ++ E + V PS W+++ RL S A ++ +G + L + V+
Sbjct: 340 QDL-EVREKESATFLCEV-PQPSTEAAWFKEETRLWAS--AKYGIEEEGTERRLTVRNVS 395
Query: 3333 TRDAGVYTC 3341
D VY C
Sbjct: 396 ADDDAVYIC 404
Score = 84.2 bits (199), Expect = 7e-15
Identities = 67/204 (32%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + G+ A L+C + G P P V W K+ V A +Q +G LTI D+ +
Sbjct: 16 PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ-DGDLYRLTILDLAL 74
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G+Y C A N G+A L V +A+A + P F +R
Sbjct: 75 GDSGQYVCRARNAIGEAFAAVGLQV-------DAEAAC---------AEQAPHFLLRPTS 118
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQD-EQFHTLEIAPTNLDD 3234
RV+ C+V GSP P VSW KDG + D R + ++ + L I D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD 3258
GG YEV A N GA S LVVD
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVD 202
Score = 84.2 bits (199), Expect = 7e-15
Identities = 75/285 (26%), Positives = 120/285 (42%), Gaps = 27/285 (9%)
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
PS S P F +++ + +C + GQP+P + WFKD K + D Y
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENS--VWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
G +L I P D G Y C AENS V + + V+ T + + + +
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 2803 IARQSLESRR-------------PHFGNVLTDYQVARGGTIG-LQVEIRGCPT-RVEWLR 2847
A+ L SR P L D QVA G + Q++++G P R+ W +
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 2848 EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD 2907
+G+ +T + R+ ++ L+TL + VT +SG Y +A G +A + V P +
Sbjct: 5297 DGQPLT-ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 2908 LDGKPAVIVGR---PEKDI------LISVGEDINISFRTQGEPKP 2943
+ KPA V P + + + G I S + +G P P
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVP 5400
Score = 79.8 bits (188), Expect = 2e-13
Identities = 70/310 (22%), Positives = 118/310 (38%), Gaps = 12/310 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L+C ++ + P V+W ++ + ++R L L +L+ DS +Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N G + L+V + P F +E CR+ G P P ++W
Sbjct: 84 ARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSW 143
Query: 2728 FKDDKQI--PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH--FVN 2783
KD +++ P R + L + L I P D GTY +AEN + V+
Sbjct: 144 SKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVD 202
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV------LTDYQVARGGTIGLQVEIR 2837
++ P TA ++ E+ R V G L +
Sbjct: 203 SDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVT 262
Query: 2838 GCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDM 2896
G P W ++G+ VTE R+ Q + L + +++ GLYTC A + G
Sbjct: 263 GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYS 322
Query: 2897 NAAITVVQPS 2906
+ + V +P+
Sbjct: 323 SVLVVVREPA 332
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 6125
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 6186 NRLGSARASAELRI 6199
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 6124
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 2770 EN 2771
N
Sbjct: 6185 VN 6186
Score = 68.5 bits (160), Expect = 4e-10
Identities = 107/437 (24%), Positives = 165/437 (37%), Gaps = 49/437 (11%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ L C+I G P P+++W KD + + + R++ D + RL I + DSG Y C+A
Sbjct: 26 DATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLTILDLALGDSGQYVCRA 84
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N++ F QV AE+ PHF T +V G
Sbjct: 85 RNAIGEA-------FAAVGLQVDAEAACAEQA-----------PHFLLRPTSIRVREGSE 126
Query: 2830 IGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQ--GLYTLALSDVTETESGLYTCR 2886
+ + G P V W ++GR + E RV VE+ L + + G Y R
Sbjct: 127 ATFRCRVGGSPRPAVSWSKDGRRLGEP-DGPRVRVEELGEASALRIRAARPRDGGTYEVR 185
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI--LISVGEDINISFRTQGEPKPK 2944
A + G AA+ V D A RP L++ + + R +G P
Sbjct: 186 AENPLGAASAAAALVV------DSDAADTASRPGTSTAALLAHLQRRREAMRAEGAP--- 236
Query: 2945 AVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP 3004
A P C V G + + +P+ P +K + L+ EG V
Sbjct: 237 ASPPSTGTRTCTVTEGKHARLSCYVTGEPK---PETVWKKDGQLV-TEGRRHVVYEDAQE 292
Query: 3005 LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
KQ + + T N G QT SS+ V + F L L++
Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVG-----QTYSSVLVVVREPAVPFKKRLQ-DLEVRE 346
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E+A C V +P W K + A + + G + LT+++++ DD+ Y C
Sbjct: 347 KESATFLCEVP-QPSTEAAWFKEETRLWASA-KYGIEEEGTERRLTVRNVSADDDAVYIC 404
Query: 3125 EATNTHGKASTYARLAV 3141
E T + T A LAV
Sbjct: 405 E---TPEGSRTVAELAV 418
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 6088 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 6124
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 3243 RNNSGA 3248
N G+
Sbjct: 6185 VNRLGS 6190
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 6088 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 6125
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 6126 QFTCTIEGAPYPQIRWYKD 6144
Score = 60.1 bits (139), Expect = 1e-07
Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
V+ YP+ + W++DG L S MT D+ L + +VT D+G Y SN +G A
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+S ++ V G D+ E + V VP P + + + ++G ++ +V G
Sbjct: 5343 YSSARLLVRGPDEPEE-KPASDVHEQLVP----PRMLERFTPKKVKKGSSITFSVKVEGR 5397
Query: 3411 PKPDVYWLRD 3420
P P V+WLR+
Sbjct: 5398 PVPTVHWLRE 5407
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 6013 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 6072 LILDSLTGVDSGQYMCFAASA 6092
Score = 56.8 bits (131), Expect = 1e-06
Identities = 62/283 (21%), Positives = 114/283 (40%), Gaps = 36/283 (12%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K ++ L + A +D+ EY
Sbjct: 1086 AEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEY 1144
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L + + ++ A +L C + QP +
Sbjct: 1145 SC----EAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAE---AGTTAMLSCEV-AQPQTE 1196
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + + RL + D+G Y+C+A + Q+ H
Sbjct: 1197 VTWYKDGKKLSSSSKVR-MEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQL-H---- 1250
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+T K A++ L V + + G + L E+ T V
Sbjct: 1251 -----------ITEPKAVFAKEQL---------VHNEVRTEAGASATLSCEVAQAQTEVT 1290
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ + L + + ++G YTC A
Sbjct: 1291 WYKDGKKLSSSSK-VRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 56.0 bits (129), Expect = 2e-06
Identities = 70/283 (24%), Positives = 112/283 (39%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V+W K+G ++ ++ + G L ++ D G YS
Sbjct: 996 AGASATLSCEV-AQAQTEVMWYKDGKKLSSSL-KVHVEAKGCRRRLVVQQAGKTDAGDYS 1053
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ ++ RL + + ++ + + E AE A
Sbjct: 1054 CEA---RGQRVSF-RLHITEPKMMFAKEQSVHNEVQAE-------------------AGA 1090
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 1091 SAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAG 1149
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
VS H + KG+ A E E + G +S V A P VTWY+
Sbjct: 1150 GQR--VSFHLHITEPKGV---FAKEQSVHNE--VQAEAGTTAMLSCEV-AQPQTEVTWYK 1201
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + + L + V DAG Y+C A +
Sbjct: 1202 DGKKLSSSSKVRMEV-KGCTRRLVVQQVGKADAGEYSCEAGGQ 1243
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/178 (26%), Positives = 74/178 (41%), Gaps = 14/178 (7%)
Query: 2591 TRKP-VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
T KP VFS LTD T EG + L C S+ D V W ++G L + +
Sbjct: 3092 TEKPSVFSRELTDATITEGEDLTLVCET-STCDIPVCWTKDGKTLRGSARCQLSHEGHRA 3150
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
L + A DS Y C E G +S+ ++V+ A P+ F +++D L
Sbjct: 3151 QLLITGATLQDSGRYKC----EAGGACSSSIVRVH----ARPV--RFQEALKDLEVLEGG 3200
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + P + W + + +Y + + L + N P+DSG Y+C
Sbjct: 3201 AATLRCVLSSVAAP-VKWCYGNNVLRPGDKY-SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 54.0 bits (124), Expect = 9e-06
Identities = 65/301 (21%), Positives = 117/301 (38%), Gaps = 40/301 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + VTWY++G L + K R ++ L V +D+ EY
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S L + +R A L C + Q +
Sbjct: 1237 SC----EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTE---AGASATLSCEV-AQAQTE 1288
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + A + +L + D+G YTC+A +++ ++
Sbjct: 1289 VTWYKDGKKLSSSSKVR-IEAAGCMRQLVVQQAGQADAGEYTCEAGG----QRLSFHLD- 1342
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
V+ K A++ L R+ Q G L E+ T V
Sbjct: 1343 -----------VSEPKAVFAKEQLAHRK---------VQAEAGAIATLSCEVAQAQTEVT 1382
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
W ++G+ ++ + R+ L + + ++G Y+C A G ++ ++ V +
Sbjct: 1383 WYKDGKKLSSSSK-VRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAE 1437
Query: 2905 P 2905
P
Sbjct: 1438 P 1438
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGL 2648
S PVF T L ++ +G V C V P+V W+++G LL+ Y + G
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 2649 ITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
L + VP+D Y C EN G ST A L+V
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 52.4 bits (120), Expect = 3e-05
Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC ++ S +L V E + + R+ A L C + Q +
Sbjct: 1605 SCKAGDQR----LSFHLHV---AEPKVVFAKEQPAHREVQAEAGASATLSCEV-AQAQTE 1656
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+TW+KD K++ S + + RL + ++G Y+C+A
Sbjct: 1657 VTWYKDGKKLSSSSKVRV-EAVGCTRRLVVQQAGQAEAGEYSCEA 1700
Score = 52.0 bits (119), Expect = 4e-05
Identities = 75/289 (25%), Positives = 115/289 (39%), Gaps = 47/289 (16%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+TA L C + K P V W K GHE + R + + +G C L I+ + + D G YSC
Sbjct: 3728 GDTATLWCELS-KAAP-VEWRK-GHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSC 3784
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R + P +F ++++ +
Sbjct: 3785 VC----GQERTSATLTV---RAL-------------------PARFIEDVKNQEAREGAT 3818
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I ++ D G Y
Sbjct: 3819 AVLQCELSKAAP--VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEY------ 3870
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL--HEGDELRISAVVEAYPSVGVTWY 3302
SC CG AP+ EPL L EG + + + P+ V W
Sbjct: 3871 -----SCVCGQERTSATLTVRAPQ-PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWS 3923
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
+ G++L+ + R L + EL L + D G YTCT ++ A+
Sbjct: 3924 KGGLQLQANGRREPRL-QGCTAELVLQDLQREDTGEYTCTCGSQATSAT 3971
Score = 51.2 bits (117), Expect = 6e-05
Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D A E +C +S D V W NG+ L N + TL + + +
Sbjct: 2564 LQDAEATEEGWASFSCE-LSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRA 2622
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ V + +STSA L+V P F +++ D L L+C +
Sbjct: 2623 DAG----IVRASSLKVSTSARLEVRVK------PVVFLKALDDLSAEERGTLALQCEV-S 2671
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
P + W KD Q+ +Y + A G L + + +PED+G YTC
Sbjct: 2672 DPEAHVVWRKDGVQLGPSDKYDFLHTA-GTRGLVVHDVSPEDAGLYTC 2718
Score = 51.2 bits (117), Expect = 6e-05
Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 17/196 (8%)
Query: 2575 EARSVISEKRTLSRNSTR--KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV 2632
E V ++RT + + R +PVF L A EGS L C +S TV W + G+
Sbjct: 3869 EYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGL 3927
Query: 2633 LLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPI 2692
L + +L L + + D+ EY+CT G+ +TSA L V A+P+
Sbjct: 3928 QLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTV----TAAPV 3979
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCR 2751
F R ++ + E C + + W K Q+ +YQ + DG
Sbjct: 3980 --RFLRELQHQ-EVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQ--MVQDGAAAE 4034
Query: 2752 LAIDNPTPEDSGTYTC 2767
L + ED+G YTC
Sbjct: 4035 LLVRGVEQEDAGDYTC 4050
Score = 50.4 bits (115), Expect = 1e-04
Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRL 2752
P F+ + DT + L LEC + + + W KD ++ +DGR+ L DG C L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL-TDGRHHHIDQLGDGTCSL 4956
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITH--FVNFTGRESQ 2790
I D+G YTC+ N Q+TH V +G ES+
Sbjct: 4957 LITGLDRADAGCYTCQVSNKF--GQVTHSACVVVSGSESE 4994
Score = 50.0 bits (114), Expect = 1e-04
Identities = 40/140 (28%), Positives = 57/140 (40%), Gaps = 22/140 (15%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG R+S V P W +DG + RR ++ D L + D G+YT
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDT 3400
CTASN VG+ +S V VV P VP+ K + + E RE ++
Sbjct: 311 CTASNLVGQTYSSVLV---------------VVREPAVPFKK------RLQDLEVREKES 349
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
CE V P + W ++
Sbjct: 350 ATFLCE-VPQPSTEAAWFKE 368
Score = 50.0 bits (114), Expect = 1e-04
Identities = 84/361 (23%), Positives = 138/361 (38%), Gaps = 58/361 (16%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG TA L+C V +P V W K+G ++ + ++ + G L ++ + D G YS
Sbjct: 1180 AGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSS-KVRMEVKGCTRRLVVQQVGKADAGEYS 1237
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G +L + + V+ + + E R +A
Sbjct: 1238 CEA----GGQRVSFQLHITEPKAVFAKEQLVHNEV-------------------RTEAGA 1274
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y T
Sbjct: 1275 SATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY--TCE 1331
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+S H + K + A E + + G +S V A VTWY+
Sbjct: 1332 AGGQRLSFHLDVSEPKAV---FAKEQLAHRK--VQAEAGAIATLSCEV-AQAQTEVTWYK 1385
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
DG +L S + M + L + D G Y+C A + R S S V
Sbjct: 1386 DGKKLSSSSKVRMEAVGCTR-RLVVQQACQADTGEYSCEAGGQ--RLSFSLDV------- 1435
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLK 3423
+EP+ VV + + P +E +A+ G + + CE V + +V W +D K
Sbjct: 1436 -AEPK---VVFAKEQPVHRE---------VQAQAGASTTLSCE-VAQAQTEVMWYKDGKK 1481
Query: 3424 V 3424
+
Sbjct: 1482 L 1482
Score = 50.0 bits (114), Expect = 1e-04
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLE 2652
P+FS D A G ++L C V S +D W ++GV L D + + +L DG +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSA 2679
+ +D+ Y+C V N+ G ++ SA
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 49.6 bits (113), Expect = 2e-04
Identities = 51/177 (28%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLIT 2650
+PV F L D +EG L C V+SS V W Y N VL KY + ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGD-KYSLRQEGAMLE 3240
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L V N P DS YSC+ G +TSA L V + +P F +R+
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTV------TALPAQFIGKLRNKEATEGAT 3290
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + + P + W K + + RY +C L I D+ Y+C
Sbjct: 3291 ATLRCEL-SKAAP-VEWRKGSETLRDGDRY-CLRQDGAMCELQIRGLAMVDAAEYSC 3344
Score = 49.6 bits (113), Expect = 2e-04
Identities = 81/357 (22%), Positives = 133/357 (37%), Gaps = 47/357 (13%)
Query: 3001 GITPLNSFDAFNLKQ-GEEYHFRVTPRNRYGWGESS----QTSSSIGVGLAGDRPEFVDI 3055
G L D ++L+Q G ++ + GE S Q +S + + +P F +
Sbjct: 3836 GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREP 3895
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
L L+ G TA L C + +P VVW K G +++ GR + G L ++D+
Sbjct: 3896 LQS-LQAEEGSTATLQCELS-EPTATVVWSKGGLQLQAN-GRREPRLQGCTAELVLQDLQ 3952
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+D G Y+C T G +T A L V P +F L+
Sbjct: 3953 REDTGEYTC----TCGSQATSATLTVTA----------------------APVRFLRELQ 3986
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ V L C+ + V W K ++ + QD L + +D
Sbjct: 3987 HQEVDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA-VVEAY 3294
G Y ++G H + +R P+F L+ L + GD R+ + +A
Sbjct: 4046 GDYTC----DTG----HTQSMASLSVRV-PRPKFKTRLQSL-EQETGDIARLCCQLSDAE 4095
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
V W ++GV L + M + EL + + +D G Y C + AS
Sbjct: 4096 SGAVVQWLKEGVELHAGPKYEMR-SQGATRELLIHQLEAKDTGEYACVTGGQKTAAS 4151
Score = 49.2 bits (112), Expect = 3e-04
Identities = 38/166 (22%), Positives = 67/166 (40%), Gaps = 9/166 (5%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLL-DNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T EG +L+C V P W ++G L+ + + + L++L SD
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+CT N G +S + V P P F + ++D + C + QP
Sbjct: 308 LYTCTASNLVGQTYSSVLVVV-----REPAVP-FKKRLQDLEVREKESATFLCEV-PQPS 360
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ WFK++ ++ + +Y RL + N + +D Y C+
Sbjct: 361 TEAAWFKEETRLWASAKY-GIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 49.2 bits (112), Expect = 3e-04
Identities = 63/284 (22%), Positives = 113/284 (39%), Gaps = 38/284 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1362 AEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEY 1420
Query: 2665 SCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
SC E G S +L V P + P R+ A L C + Q
Sbjct: 1421 SC----EAGGQRLSFSLDVAEPKVVFAKEQPVH----REVQAQAGASTTLSCEV-AQAQT 1471
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++ W+KD K++ + + RL + +G Y+C+A + +++ ++
Sbjct: 1472 EVMWYKDGKKLSFSSKVR-MEAVGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLH 1526
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V K A++ SR + Q G + L E+ T V
Sbjct: 1527 ------------VAEPKAVFAKEQPASR---------EVQAEAGTSATLSCEVAQAQTEV 1565
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ L + + + ++G Y+C+A
Sbjct: 1566 TWYKDGKKLSSSSK-VRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 6120 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 6179
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 6180 YECELVNRLGSARASAELRI 6199
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 6123
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 6124 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 6162
Score = 47.6 bits (108), Expect = 8e-04
Identities = 69/288 (23%), Positives = 107/288 (37%), Gaps = 35/288 (12%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L+ AG +A L+C V + V W K+G ++ + ++ + G L ++ D
Sbjct: 899 KLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVCMEATGCTRRLVVQQAGQAD 956
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G YSCEA G L V + V+ D E AE
Sbjct: 957 AGEYSCEA----GGQRLSFHLDVKEPKVVFAKDQVAHSEVQAE----------------- 995
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
A L+C+V +V WYKDG+++ + + L + D G Y
Sbjct: 996 --AGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
AR + H + + + A E E + G +S V A
Sbjct: 1053 SCEARGQRVSFRLH---ITEP--KMMFAKEQSVHNE--VQAEAGASAMLSCEV-AQAQTE 1104
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
VTWY+DG +L S + M + + L L DAG Y+C A +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEV-KGCTRRLVLPQAGKADAGEYSCEAGGQ 1151
Score = 47.6 bits (108), Expect = 8e-04
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Query: 2664 YSCTVENENGAISTSA-NLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y + + G I A N + +P T R +RD + ++ VLEC++ +
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQV-SRAS 2317
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKA 2769
++ WFK +++ +Y+ ++DG+ R L I + ED TYTC A
Sbjct: 2318 AQVRWFKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Score = 47.6 bits (108), Expect = 8e-04
Identities = 55/221 (24%), Positives = 90/221 (40%), Gaps = 25/221 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAEN 2771
+ +++G P P++ WFKD + + + + + D + L I + T EDSG Y N
Sbjct: 5281 QLKVKGYPAPRLYWFKDGQPLTASAHIR---MTDKKILHTLEIISVTREDSGQYAAYISN 5337
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
++ + + G + + + + LE P +V +G +I
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPK--------KVKKGSSIT 5389
Query: 2832 LQVEIRGCPT-RVEWLREG--RSVTEVYRNA---RVFVEQGLYTLALSDVTETESGLYTC 2885
V++ G P V WLRE R V + + V ++L L DV G YTC
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 5449
Query: 2886 RAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
A +A G +A++ V G P V K+ LIS
Sbjct: 5450 IASNAAGQALCSASLHV------SGLPKVEEQEKVKEALIS 5484
Score = 46.8 bits (106), Expect = 0.001
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG A L+C V + V W K+G ++ + ++ + G L ++ D G YS
Sbjct: 1364 AGAIATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRMEAVGCTRRLVVQQACQADTGEYS 1421
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ +++ L V + V+ + + RE A QA
Sbjct: 1422 CEAG---GQRLSFS-LDVAEPKVVFAKEQPVHREVQA-------------------QAGA 1458
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V WYKDG+++ + + L + G Y A
Sbjct: 1459 STTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA- 1516
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
S +S H + K + A P + G +S V A VTWY+
Sbjct: 1517 -GSQRLSFHLHVAEPKAVFAKEQPA-----SREVQAEAGTSATLSCEV-AQAQTEVTWYK 1569
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + L + DAG Y+C A ++
Sbjct: 1570 DGKKLSSSSKVRMEAVGCTR-RLVVQEAGQADAGEYSCKAGDQ 1611
Score = 46.4 bits (105), Expect = 0.002
Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 22/224 (9%)
Query: 2570 SKAFSEARSVISEKRTLSRNST----RKPVFSTFLTDRTAVEGSRV-KLTCSVISSSDPT 2624
S ++ A+ +S + ST + P L D G+R+ K V P
Sbjct: 5232 SSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPR 5291
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+ W+++G L R L TLE+++ DS +Y+ + N GA +SA L V
Sbjct: 5292 LYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Query: 2685 PSFEASP----------IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI 2734
E +PP + + ++ G+P+P + W +++ +
Sbjct: 5352 GPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 2735 ------PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
P Y A + +D + GTYTC A N+
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLD-VGRQHQGTYTCIASNA 5454
Score = 46.0 bits (104), Expect = 0.002
Identities = 66/285 (23%), Positives = 112/285 (39%), Gaps = 40/285 (14%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K + L V A +D+ EY
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L V E + + + A L C + Q +
Sbjct: 961 SC----EAGGQRLSFHLDVK---EPKVVFAKDQVAHSEVQAEAGASATLSCEV-AQAQTE 1012
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ W+KD K++ S + A G RL + D+G Y+C+A
Sbjct: 1013 VMWYKDGKKLSSS--LKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA-------------- 1056
Query: 2784 FTGRESQVSPNV-VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTR 2842
R +VS + +T K A++ +V + Q G + L E+ T
Sbjct: 1057 ---RGQRVSFRLHITEPKMMFAKEQ---------SVHNEVQAEAGASAMLSCEVAQAQTE 1104
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
V W ++G+ ++ + + V+ L L + ++G Y+C A
Sbjct: 1105 VTWYKDGKKLSSSSK-VGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Score = 46.0 bits (104), Expect = 0.002
Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 36/302 (11%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S +D +W R+G+ + + TL + P DS E + T
Sbjct: 2100 LSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG----VHT 2155
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
SA L V + +P +F+R ++D + ++ LEC + +P + W KD ++ +
Sbjct: 2156 SARLVV------TELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRA- 2207
Query: 2738 GRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
G+ A A G CR L I D G Y C A ++ Q + V GR + V
Sbjct: 2208 GKTMAI-AAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRV 2262
Query: 2797 TAE---KTRIARQSLESRRP--------HFGNVLTDYQVARGGTIGLQVEIRGCPTRVEW 2845
AE + + ++ ESR L D L+ ++ +V W
Sbjct: 2263 LAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRW 2322
Query: 2846 LREGRSVTEVYRNARVFVEQGLY-TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
+ + + + V GLY L +SDV + YTC A G+V +A V +
Sbjct: 2323 FKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEE 2376
Query: 2905 PS 2906
S
Sbjct: 2377 QS 2378
Score = 46.0 bits (104), Expect = 0.002
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 15/168 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L ++ A EG+ L C +S + P V W + L + +Y + + L++
Sbjct: 3280 LRNKEATEGATATLRCE-LSKAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMV 3337
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+AEYSC E TSA+L + P+P F +R + L C +
Sbjct: 3338 DAAEYSCVCGEER----TSASLTI------RPMPAHFIGRLRHQESIEGATATLRCEL-S 3386
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ P + W K + + DG + VC L I D+G Y+C
Sbjct: 3387 KAAP-VEWRKGRESL-RDGDRHSLRQDGAVCELQICGLAVADAGEYSC 3432
Score = 45.6 bits (103), Expect = 0.003
Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 11/188 (5%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISS-SDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+P F T L G +L C + + S V W + GV L KY + L
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATREL 4126
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ D+ EY+C G T+A+L+V P T R + D A+ ++
Sbjct: 4127 LIHQLEAKDTGEYACV----TGGQKTAASLRV-----TEP-EVTIVRGLVDAEVTADEDV 4176
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C + + W + S+ + + L + TPED+GT + N
Sbjct: 4177 EFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGN 4236
Query: 2772 SVWTDQIT 2779
+ Q+T
Sbjct: 4237 HASSAQLT 4244
Score = 45.2 bits (102), Expect = 0.004
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 13/184 (7%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN 2655
F + L+ A EG C V+S SD V W+R+G LL K+ +L + +
Sbjct: 1901 FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISD 1959
Query: 2656 AVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLEC 2715
V D+ + TVE E GA S+SA L+V + P F + + + + LE
Sbjct: 1960 LVLEDAGQ--ITVEAE-GA-SSSAALRVREA------PVLFKKKLEPQTVEERSSVTLEV 2009
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +P P++ W ++ + + G+ + RL + N D G + C+ +
Sbjct: 2010 ELT-RPWPELRWTRNATAL-APGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ 2067
Query: 2776 DQIT 2779
++T
Sbjct: 2068 AKLT 2071
Score = 45.2 bits (102), Expect = 0.004
Identities = 51/205 (24%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 2569 RSKAFSEARSVISEKRTLSRNST-----RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP 2623
R A S+A V+ R L+ ++ R L D+ G V+L C + + P
Sbjct: 2797 REAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2624 TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
V W ++ + KY + L + A D+ EY+C VE A ++A+L V
Sbjct: 2857 -VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE----ASKSTASLHV 2911
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
FT + + + V C+ P +TW K ++ + G++Q
Sbjct: 2912 EEKANC------FTEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQP- 2963
Query: 2744 YLADGV-CRLAIDNPTPEDSGTYTC 2767
+G+ RL I DS TYTC
Sbjct: 2964 -SQEGLTLRLTISALEKADSDTYTC 2987
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 6097 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 6156 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 44.8 bits (101), Expect = 0.006
Identities = 49/192 (25%), Positives = 79/192 (41%), Gaps = 19/192 (9%)
Query: 2579 VISEKRTLSRNSTRKPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
V ++RT S T + + + F+ D + A EG+ L C ++S+ P V W + L
Sbjct: 3521 VCGQERT-SATLTIRALPARFIEDVKNQEAREGATAVLQCE-LNSAAP-VEWRKGSETLR 3577
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT 2695
+ +Y + L++ +D+ EYSC E TSA L V +P
Sbjct: 3578 DGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQER----TSAMLTV------RALPIK 3627
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
FT +R+ VL C + + + W+K + + DG + C L I
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETL-RDGDRHSLRQDGARCELQIR 3684
Query: 2756 NPTPEDSGTYTC 2767
ED+G Y C
Sbjct: 3685 GLVAEDAGEYLC 3696
Score = 44.8 bits (101), Expect = 0.006
Identities = 19/66 (28%), Positives = 35/66 (53%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+VE+ + +T P +PP + + P+F+ + ++ E ++G V +C V G P P
Sbjct: 5097 RVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPS 5156
Query: 3415 VYWLRD 3420
V W +D
Sbjct: 5157 VRWFKD 5162
Score = 43.6 bits (98), Expect = 0.013
Identities = 68/284 (23%), Positives = 108/284 (38%), Gaps = 39/284 (13%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V W K+G ++ + ++ + G L ++ + G YS
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRVEAVGCTRRLVVQQAGQAEAGEYS 1697
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G RL V E + ++ ER E P D
Sbjct: 1698 CEA----GGQQLSFRLQVA------ELEPQIS-ERPCRRE----PLVVKEHED------- 1735
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
+ LT + V+W KDG E+ KR HTL + + D +Y
Sbjct: 1736 -IILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRV- 1793
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG-VTWY 3302
GA + V++ VA +FC LEP+ G ++ E P+ V W
Sbjct: 1794 ---GAEGQDFPVQVEE-----VAAKFCRLLEPVCGELGG---TVTLACELSPACAEVVWR 1842
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+LR +R M + + L + + DAG Y C + ++
Sbjct: 1843 CGNTQLRVGKRFQMVAEGPVR-SLTVLGLRAEDAGEYVCESRDD 1885
Score = 43.2 bits (97), Expect = 0.017
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 32/226 (14%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V+W KDG + + L + DD G+YE +R G ++ +
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAYQLSV--- 791
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+G+ ++ + + + G EA+ V V WY+DG+ L S +
Sbjct: 792 QGLARFLHKDMAGSC--VDAVAGGPAQFECETSEAH--VHVHWYKDGMELGHSGERFLQE 847
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
D + L A VT +D G Y+C VG S ++ V SEP+ V
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV------SEPK---------V 888
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
++KE + RK +A G + + CE V + +V W +D K+
Sbjct: 889 VFAKEQLARRK---LQAEAGASATLSCE-VAQAQTEVTWYKDGKKL 930
Score = 43.2 bits (97), Expect = 0.017
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 14/174 (8%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E + LT ++ + S TVTW ++GV + ++ TL V A DSA YSC
Sbjct: 1732 EHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
V E + +P + + F R + + L C + ++
Sbjct: 1792 RVGAEG---------QDFP-VQVEEVAAKFCRLLEPVCGELGGTVTLACEL-SPACAEVV 1840
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
W + Q+ R+Q +A+G R L + ED+G Y C++ + + Q+T
Sbjct: 1841 WRCGNTQLRVGKRFQ--MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLT 1892
Score = 42.7 bits (96), Expect = 0.022
Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 14/187 (7%)
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR-MTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E L C + +P V W+K+G VE AG+ M G LTI D+G Y C
Sbjct: 2181 EKVTLECELS-RPNVDVRWLKDG--VELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC 2237
Query: 3125 EATNTHGKAS------TYA---RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+A + AS TY R + D + A+ R+ + P LR
Sbjct: 2238 DAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR 2297
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D+ + L CQV +V W+K +E+ + D + L I+ + +D
Sbjct: 2298 DKIAMEKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDE 2356
Query: 3236 GVYEVTA 3242
Y A
Sbjct: 2357 DTYTCDA 2363
Score = 42.3 bits (95), Expect = 0.030
Identities = 67/274 (24%), Positives = 110/274 (40%), Gaps = 43/274 (15%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S VTW ++G L KY + G L V + D+ Y C + G I+
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAY 787
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
+++ F + S D +A EC + + W+KD ++
Sbjct: 788 QLSVQGLARF----LHKDMAGSCVDA--VAGGPAQFECE-TSEAHVHVHWYKDGMELGHS 840
Query: 2738 GRYQAFYLAD-GV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNV 2795
G + F D G RL T +D GTY+C+ V D V+F R S+ P V
Sbjct: 841 G--ERFLQEDVGTRHRLVAATVTRQDEGTYSCR----VGEDS----VDFRLRVSE--PKV 888
Query: 2796 VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEV 2855
V A K ++AR+ L Q G + L E+ T V W ++G+ ++
Sbjct: 889 VFA-KEQLARRKL--------------QAEAGASATLSCEVAQAQTEVTWYKDGKKLSS- 932
Query: 2856 YRNARVFVEQGLYT--LALSDVTETESGLYTCRA 2887
+++V +E T L + + ++G Y+C A
Sbjct: 933 --SSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 42.3 bits (95), Expect = 0.030
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 17/170 (10%)
Query: 2606 VEGSRVKLTC--SVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+EG C S S+SDP + W G + + +++ L V A PSD+ E
Sbjct: 2748 LEGESCSFECVLSHESASDPAM-WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE 2806
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
+V +++ A+L V P + + D + ++ L C + P
Sbjct: 2807 VVFSVRG----LTSKASLIVRER------PAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENS 2772
+ W KD K I +Y + +G + L I + +D+G YTC+ E S
Sbjct: 2857 -VHWLKDRKAIRKSQKYDV--VCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/171 (26%), Positives = 64/171 (37%), Gaps = 13/171 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLITLEVLNAVP 2658
L D EGS C + ++ V W+ + L N+L G L +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
DS T+ E G SA L+V P F+R + D +L L C
Sbjct: 3071 KDSG----TIYFEAGDQRASAALRVTEK------PSVFSRELTDATITEGEDLTLVCETS 3120
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+P + W KD K + R Q + +L I T +DSG Y C+A
Sbjct: 3121 TCDIP-VCWTKDGKTLRGSARCQLSHEGHRA-QLLITGATLQDSGRYKCEA 3169
Score = 42.3 bits (95), Expect = 0.030
Identities = 74/294 (25%), Positives = 110/294 (37%), Gaps = 46/294 (15%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K G E R + + +G C L I +++ D G YSC
Sbjct: 3816 GATAVLQCELS-KAAP-VEWRK-GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC 3872
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R+ + P F L+ + +
Sbjct: 3873 VC----GQERTSATLTV----------------RAPQ------PVFREPLQSLQAEEGST 3906
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C+ + P V W K G ++ + RR Q T E+ +L R
Sbjct: 3907 ATLQCE-LSEPTATVVWSKGGLQLQANGRREPRL--QGCTAELVLQDLQ---------RE 3954
Query: 3245 NSGAVSCHCGLVVDKG-IRAYVAP-EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
++G +C CG + AP F L+ ++ EG + + V W
Sbjct: 3955 DTGEYTCTCGSQATSATLTVTAAPVRFLRELQH-QEVDEGGTAHLCCELSR-AGASVEWR 4012
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ ++L P + M D EL + V DAG YTC + AS S +V
Sbjct: 4013 KGSLQLFPCAKYQMVQD-GAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/174 (25%), Positives = 64/174 (36%), Gaps = 4/174 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
P + VV ++ V+L+W + Y+VE GA G R + P
Sbjct: 4526 PEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEV-KEGATGQWRLCH-ELVPGPECVV 4583
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANL 3070
L GE Y FRV G GE ++ + P ++ AGE +L
Sbjct: 4584 DGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSL 4643
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
V + V+W K G E + GR G L IK +D+G Y C
Sbjct: 4644 ELEVVAE-AGEVIWHK-GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 41.5 bits (93), Expect = 0.052
Identities = 66/284 (23%), Positives = 101/284 (35%), Gaps = 34/284 (11%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+AG A C V V W K+G E+ R + G L + DEG Y
Sbjct: 810 VAGGPAQFECETSEAHVH-VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTY 868
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
SC G+ S RL V + V+ + +R+ AE A
Sbjct: 869 SCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQAE-------------------AG 905
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 906 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+S H + K + A + E + G +S V A V WY
Sbjct: 965 --GGQRLSFHLDV---KEPKVVFAKDQVAHSE--VQAEAGASATLSCEV-AQAQTEVMWY 1016
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+DG +L S + + + + L + DAG Y+C A +
Sbjct: 1017 KDGKKLSSSLK-VHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Score = 41.1 bits (92), Expect = 0.068
Identities = 81/368 (22%), Positives = 141/368 (38%), Gaps = 59/368 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+++ AG + L+C V + V+W K+G ++ + ++ + G L ++
Sbjct: 1451 EVQAQAGASTTLSCEV-AQAQTEVMWYKDGKKLSFSS-KVRMEAVGCTRRLVVQQAGQAV 1508
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G YSCEA G L V + V+ + RE AE
Sbjct: 1509 AGEYSCEA----GSQRLSFHLHVAEPKAVFAKEQPASREVQAEAG--------------- 1549
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
AT L+C+V +V+WYKDG+++ + L + D G Y
Sbjct: 1550 TSAT----LSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A + +S H + K + A P + G +S V A
Sbjct: 1605 SCKAGDQR--LSFHLHVAEPKVVFAKEQPA-----HREVQAEAGASATLSCEV-AQAQTE 1656
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTWY+DG +L S + + ++ G L + +AG Y+C E G S +++
Sbjct: 1657 VTWYKDGKKLSSSSK--VRVEAVGCTRRLVVQQAGQAEAGEYSC----EAGGQQLSFRLQ 1710
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V EP+I + P +EP+ + +E + +I+ + V W
Sbjct: 1711 V----AELEPQI------SERPCRREPLVV--------KEHEDIILTATLATPSAATVTW 1752
Query: 3418 LRDFLKVR 3425
L+D +++R
Sbjct: 1753 LKDGVEIR 1760
Score = 41.1 bits (92), Expect = 0.068
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 8/126 (6%)
Query: 2690 SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK-ITWFKDDKQIPSDGRYQAFYLADG 2748
S IP TR + +VL C R P PK + W+KDD + +++ L
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFR--PAPKAVQWYKDDTPLSPSEKFK-MSLEGQ 2521
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
+ L I P D+G Y C+A ++ + ++T RE V+ + AE T S
Sbjct: 2522 MAELRILRLMPADAGVYRCQAGSAHSSTEVT----VEAREVTVTGPLQDAEATEEGWASF 2577
Query: 2809 ESRRPH 2814
H
Sbjct: 2578 SCELSH 2583
Score = 41.1 bits (92), Expect = 0.068
Identities = 43/181 (23%), Positives = 68/181 (37%), Gaps = 11/181 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D EG C + +S W GV L + G + L L+ V
Sbjct: 4256 LQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTL 4315
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+ A TV G S+ A LKV T R + + L E + EC++
Sbjct: 4316 EDAG---TVSFHVGTCSSEAQLKVTAK-------NTVVRGLENVEALEGGEALFECQLSQ 4365
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQI 2778
+ TW DD+ + + + + +G+ L + N P+DS T A + V + +
Sbjct: 4366 PEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFL 4425
Query: 2779 T 2779
T
Sbjct: 4426 T 4426
Score = 40.3 bits (90), Expect = 0.12
Identities = 92/365 (25%), Positives = 137/365 (37%), Gaps = 78/365 (21%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K GHE + R + + +G C L I+ + +D G Y C
Sbjct: 3640 GATAVLRCELS-KMAP-VEWWK-GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC 3696
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
GK T A L V R + P +F LR+
Sbjct: 3697 MC----GKERTSAMLTV---RAM-------------------PSKFIEGLRNEEATEGDT 3730
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I + D G Y
Sbjct: 3731 ATLWCELSKAAP--VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEY------ 3782
Query: 3245 NSGAVSCHCG---LVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
SC CG +RA A F +E + + E + V W
Sbjct: 3783 -----SCVCGQERTSATLTVRALPA-RF---IEDVKNQEAREGATAVLQCELSKAAPVEW 3833
Query: 3302 YRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ LR R +L +DG + EL + ++ D G Y+C G+ TS + V
Sbjct: 3834 RKGSETLRGGDR--YSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV-- 3885
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R P P +EP+ +S +A EG T ++CE + +P V W +
Sbjct: 3886 -------RAPQ-------PVFREPL-----QSLQAEEGSTATLQCE-LSEPTATVVWSKG 3925
Query: 3421 FLKVR 3425
L+++
Sbjct: 3926 GLQLQ 3930
Score = 39.5 bits (88), Expect = 0.21
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 3/135 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + V+ G L +I G PT +V W ++ + V R R+ + LY
Sbjct: 7 SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGAR-FRLAQDGDLY 65
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
L + D+ +SG Y CRA +A G + V + + + RP I + G
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREG 124
Query: 2929 EDINISFRTQGEPKP 2943
+ R G P+P
Sbjct: 125 SEATFRCRVGGSPRP 139
Score = 39.1 bits (87), Expect = 0.28
Identities = 68/307 (22%), Positives = 115/307 (37%), Gaps = 43/307 (14%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
KPV F L D +A E + L C V S + V W ++GV L KY G L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
V + P D+ Y+C V G+ T A ++V+ + T+ ++ L
Sbjct: 2704 VVHDVSPEDAGLYTCHV----GSEETRARVRVH------DLHVGITKRLKTMEVLEGESC 2753
Query: 2712 VLECRIRGQPL-PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
EC + + W K + S R+QA L + P D+G
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYI-LVVREAAPSDAGE------ 2806
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
V F+ R +++ E+ + LE D VA G +
Sbjct: 2807 -----------VVFSVRGLTSKASLIVRERPAAIIKPLE-----------DQWVAPGEDV 2844
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ E+ T V WL++ +++ + + V E + L + + ++G YTC ++
Sbjct: 2845 ELRCELSRAGTPVHWLKDRKAIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Query: 2891 HGNVDMN 2897
++
Sbjct: 2904 KSTASLH 2910
Score = 38.7 bits (86), Expect = 0.36
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P V W +DGV+L PS + L G L + V+ DAG+YTC +E RA
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDF-LHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRA 2727
Score = 37.9 bits (84), Expect = 0.64
Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
V WY+D L PS + M+L +GQ+ EL + + DAGVY C A + +ST VE
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSL--EGQMAELRILRLMPADAGVYRCQAGS--AHSSTEVTVE 2554
Score = 37.5 bits (83), Expect = 0.84
Identities = 13/41 (31%), Positives = 23/41 (56%)
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+S P F+ +P++ G + C++VG+P P V W +D
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKD 46
Score = 37.5 bits (83), Expect = 0.84
Identities = 46/178 (25%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+ +R + VQA +T V + W+ DG+ + + D HTL I
Sbjct: 611 PKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTI 670
Query: 3228 --APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
P +L G + A N S + G+ A P E L +LHE +L
Sbjct: 671 REVPASL-HGAQLKFVA--NGIESSIRMEVRAAPGLTAN-KPPAAAAREVLARLHEEAQL 726
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTA 3343
+A VTW +DG L P + + G+ L + V DAG+Y C +
Sbjct: 727 LAELSDQA---AAVTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECVS 780
Score = 36.7 bits (81), Expect = 1.5
Identities = 40/168 (23%), Positives = 66/168 (39%), Gaps = 14/168 (8%)
Query: 3185 VRLTCQVIGSPP-PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V L C++ SP +V W ++ KR + +L + +D G Y +R
Sbjct: 1826 VTLACEL--SPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESR 1883
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
++ S + V + ++ F GL + EG E VV V V W+R
Sbjct: 1884 DDH--TSAQLTVSVPRVVK------FMSGLSTVVA-EEGGEATFQCVVSP-SDVAVVWFR 1933
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
DG L+PS + ++ L ++ + DAG T A A+
Sbjct: 1934 DGALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSAA 1980
Score = 36.3 bits (80), Expect = 1.9
Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GE L C +P V W K+G + A R G L I + D GR
Sbjct: 3107 ITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA-RCQLSHEGHRAQLLITGATLQDSGR 3164
Query: 3122 YSCEA 3126
Y CEA
Sbjct: 3165 YKCEA 3169
Score = 35.9 bits (79), Expect = 2.6
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLL--DNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
EGS C V S P V+W ++G L + + R + + L + A P D Y
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 2665 SCTVENENGAISTSANLKV 2683
EN GA S +A L V
Sbjct: 183 EVRAENPLGAASAAAALVV 201
Score = 35.9 bits (79), Expect = 2.6
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 3050 PEFVDILPGQLKILA--GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
P V + G ++A G A C V V VVW ++G ++ SQ +G
Sbjct: 1896 PRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-AVVWFRDGALLQPSEKFAISQ-SGASH 1953
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
LTI D+ ++D G+ + EA A+ R A V
Sbjct: 1954 SLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Score = 35.5 bits (78), Expect = 3.4
Identities = 43/195 (22%), Positives = 73/195 (37%), Gaps = 19/195 (9%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
P L D+ V V L C++ + P V W KD + + ++ + + L
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLV 2884
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-EGDEL 3285
I +L D G Y + S H V + C E L L E
Sbjct: 2885 IRGASLKDAGEYTCEVEASKSTASLH------------VEEKANCFTEELTNLQVEEKGT 2932
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ +P+ VTW + + LR S + + L ++A+ D+ YTC
Sbjct: 2933 AVFTCKTEHPAATVTWRKGLLELRASGKH-QPSQEGLTLRLTISALEKADSDTYTC---- 2987
Query: 3346 EVGRASTSGKVEVIG 3360
++G+A + ++ V G
Sbjct: 2988 DIGQAQSRAQLLVQG 3002
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 6008 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 6056
Score = 34.3 bits (75), Expect = 7.9
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 2804 ARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFV 2863
AR + + F L D GT+ LQ E+ V W ++G + + +
Sbjct: 2638 ARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWS 2889
G L + DV+ ++GLYTC S
Sbjct: 2698 -AGTRGLVVHDVSPEDAGLYTCHVGS 2722
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 103 bits (246), Expect = 1e-20
Identities = 81/267 (30%), Positives = 109/267 (40%), Gaps = 16/267 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+F R + V L+CQ++G+P P+VSW KD + V R QD + L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD-KGIRAYVAPEFCCGLEPL-YKLHEGDEL 3285
L D G Y ARN G GL VD + A AP F L P ++ EG E
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFL--LRPTSIRVREGSEA 127
Query: 3286 RISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
V P V+W +DG RL P + + L + A RD G Y A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 3345 NEVGRASTSGK--VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR----KPRSSEAR-- 3396
N +G AS + V+ D S P + + +E M P S+ R
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTC 247
Query: 3397 ---EGDTVIIECEVVGDPKPDVYWLRD 3420
EG + C V G+PKP+ W +D
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKD 274
Score = 102 bits (244), Expect = 3e-20
Identities = 142/607 (23%), Positives = 224/607 (36%), Gaps = 61/607 (10%)
Query: 2802 RIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNAR 2860
++ ++ + P F + D + G + L+ + R WL++G +T+ +
Sbjct: 4887 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 4946
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPE 2920
+ G +L ++ + ++G YTC+ + G V +A V+V E
Sbjct: 4947 DQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSAC--------------VVVSGSE 4992
Query: 2921 KDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVL 2980
+ S G +++ +FR + + P E V ++S ++P+ A
Sbjct: 4993 SEAESSSGGELDDAFRRAARRLHRLFRTKSPAE---VSDEELFLSADEGPAEPEEPADWQ 5049
Query: 2981 AYKVESWLIGAEGGARW-VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
Y+ + I A +T A L G E R S +T +
Sbjct: 5050 TYREDEHFICIRFEALTEARQAVTRFQEMFA-TLGIGVEIKLVEQGPRRVEMCISKETPA 5108
Query: 3040 SIGVG------LAGDR-PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
+ L D P F+ L Q ++ G + C V G+P+P V W K+G +E
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQ-EVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE 5167
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--A 3150
E+ M ++ L I + D G Y C A N+ G +ST A L V T ++ A
Sbjct: 5168 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAA 5227
Query: 3151 DAKLKRE--------RSAEVEGDYP-------PQFTMRLRDRRV-QATYPVRLTCQVIGS 3194
DA S E EG PQ LRD +V T + +V G
Sbjct: 5228 DATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY 5287
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
P P++ W+KDG+ + + HTLEI +D G Y N GA
Sbjct: 5288 PAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSAR 5347
Query: 3255 LVV----------DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
L+V + + P K+ +G + S VE P V W R+
Sbjct: 5348 LLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLRE 5407
Query: 3305 ----GVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
GV + P Q L L V + G YTC ASN G+A S + V
Sbjct: 5408 EAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS 5467
Query: 3360 GTDQTSE 3366
G + E
Sbjct: 5468 GLPKVEE 5474
Score = 85.4 bits (202), Expect = 3e-15
Identities = 91/309 (29%), Positives = 127/309 (41%), Gaps = 23/309 (7%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNG 3104
A P F+ + P +++ G A C V G P P V W K+G + E G R+ + G
Sbjct: 106 AEQAPHFL-LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELG 164
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEAD---------AKLK 3155
L I+ D G Y A N G AS A L V +D + A L+
Sbjct: 165 EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224
Query: 3156 RERSA-EVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR 3214
R R A EG + R V RL+C V G P P+ W KDG+ V +R
Sbjct: 225 RRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRH 284
Query: 3215 NKYQDEQFH-TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
Y+D Q + L+I D G+Y TA N G LVV +R P F L
Sbjct: 285 VVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVV---VREPAVP-FKKRL 339
Query: 3274 EPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVT 3332
+ L ++ E + V PS W+++ RL S A ++ +G + L + V+
Sbjct: 340 QDL-EVREKESATFLCEV-PQPSTEAAWFKEETRLWAS--AKYGIEEEGTERRLTVRNVS 395
Query: 3333 TRDAGVYTC 3341
D VY C
Sbjct: 396 ADDDAVYIC 404
Score = 84.2 bits (199), Expect = 7e-15
Identities = 67/204 (32%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + G+ A L+C + G P P V W K+ V A +Q +G LTI D+ +
Sbjct: 16 PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ-DGDLYRLTILDLAL 74
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G+Y C A N G+A L V +A+A + P F +R
Sbjct: 75 GDSGQYVCRARNAIGEAFAAVGLQV-------DAEAAC---------AEQAPHFLLRPTS 118
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQD-EQFHTLEIAPTNLDD 3234
RV+ C+V GSP P VSW KDG + D R + ++ + L I D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD 3258
GG YEV A N GA S LVVD
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVD 202
Score = 84.2 bits (199), Expect = 7e-15
Identities = 75/285 (26%), Positives = 120/285 (42%), Gaps = 27/285 (9%)
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
PS S P F +++ + +C + GQP+P + WFKD K + D Y
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENS--VWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
G +L I P D G Y C AENS V + + V+ T + + + +
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 2803 IARQSLESRR-------------PHFGNVLTDYQVARGGTIG-LQVEIRGCPT-RVEWLR 2847
A+ L SR P L D QVA G + Q++++G P R+ W +
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 2848 EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD 2907
+G+ +T + R+ ++ L+TL + VT +SG Y +A G +A + V P +
Sbjct: 5297 DGQPLT-ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 2908 LDGKPAVIVGR---PEKDI------LISVGEDINISFRTQGEPKP 2943
+ KPA V P + + + G I S + +G P P
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVP 5400
Score = 79.8 bits (188), Expect = 2e-13
Identities = 70/310 (22%), Positives = 118/310 (38%), Gaps = 12/310 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L+C ++ + P V+W ++ + ++R L L +L+ DS +Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N G + L+V + P F +E CR+ G P P ++W
Sbjct: 84 ARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSW 143
Query: 2728 FKDDKQI--PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH--FVN 2783
KD +++ P R + L + L I P D GTY +AEN + V+
Sbjct: 144 SKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVD 202
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV------LTDYQVARGGTIGLQVEIR 2837
++ P TA ++ E+ R V G L +
Sbjct: 203 SDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVT 262
Query: 2838 GCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDM 2896
G P W ++G+ VTE R+ Q + L + +++ GLYTC A + G
Sbjct: 263 GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYS 322
Query: 2897 NAAITVVQPS 2906
+ + V +P+
Sbjct: 323 SVLVVVREPA 332
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 6125
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 6186 NRLGSARASAELRI 6199
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 6124
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 2770 EN 2771
N
Sbjct: 6185 VN 6186
Score = 68.5 bits (160), Expect = 4e-10
Identities = 107/437 (24%), Positives = 165/437 (37%), Gaps = 49/437 (11%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ L C+I G P P+++W KD + + + R++ D + RL I + DSG Y C+A
Sbjct: 26 DATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLTILDLALGDSGQYVCRA 84
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N++ F QV AE+ PHF T +V G
Sbjct: 85 RNAIGEA-------FAAVGLQVDAEAACAEQA-----------PHFLLRPTSIRVREGSE 126
Query: 2830 IGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQ--GLYTLALSDVTETESGLYTCR 2886
+ + G P V W ++GR + E RV VE+ L + + G Y R
Sbjct: 127 ATFRCRVGGSPRPAVSWSKDGRRLGEP-DGPRVRVEELGEASALRIRAARPRDGGTYEVR 185
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI--LISVGEDINISFRTQGEPKPK 2944
A + G AA+ V D A RP L++ + + R +G P
Sbjct: 186 AENPLGAASAAAALVV------DSDAADTASRPGTSTAALLAHLQRRREAMRAEGAP--- 236
Query: 2945 AVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP 3004
A P C V G + + +P+ P +K + L+ EG V
Sbjct: 237 ASPPSTGTRTCTVTEGKHARLSCYVTGEPK---PETVWKKDGQLV-TEGRRHVVYEDAQE 292
Query: 3005 LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
KQ + + T N G QT SS+ V + F L L++
Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVG-----QTYSSVLVVVREPAVPFKKRLQ-DLEVRE 346
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E+A C V +P W K + A + + G + LT+++++ DD+ Y C
Sbjct: 347 KESATFLCEVP-QPSTEAAWFKEETRLWASA-KYGIEEEGTERRLTVRNVSADDDAVYIC 404
Query: 3125 EATNTHGKASTYARLAV 3141
E T + T A LAV
Sbjct: 405 E---TPEGSRTVAELAV 418
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 6088 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 6124
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 3243 RNNSGA 3248
N G+
Sbjct: 6185 VNRLGS 6190
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 6088 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 6125
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 6126 QFTCTIEGAPYPQIRWYKD 6144
Score = 60.1 bits (139), Expect = 1e-07
Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
V+ YP+ + W++DG L S MT D+ L + +VT D+G Y SN +G A
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+S ++ V G D+ E + V VP P + + + ++G ++ +V G
Sbjct: 5343 YSSARLLVRGPDEPEE-KPASDVHEQLVP----PRMLERFTPKKVKKGSSITFSVKVEGR 5397
Query: 3411 PKPDVYWLRD 3420
P P V+WLR+
Sbjct: 5398 PVPTVHWLRE 5407
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 6013 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 6072 LILDSLTGVDSGQYMCFAASA 6092
Score = 56.8 bits (131), Expect = 1e-06
Identities = 62/283 (21%), Positives = 114/283 (40%), Gaps = 36/283 (12%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K ++ L + A +D+ EY
Sbjct: 1086 AEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEY 1144
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L + + ++ A +L C + QP +
Sbjct: 1145 SC----EAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAE---AGTTAMLSCEV-AQPQTE 1196
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + + RL + D+G Y+C+A + Q+ H
Sbjct: 1197 VTWYKDGKKLSSSSKVR-MEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQL-H---- 1250
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+T K A++ L V + + G + L E+ T V
Sbjct: 1251 -----------ITEPKAVFAKEQL---------VHNEVRTEAGASATLSCEVAQAQTEVT 1290
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ + L + + ++G YTC A
Sbjct: 1291 WYKDGKKLSSSSK-VRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 56.0 bits (129), Expect = 2e-06
Identities = 70/283 (24%), Positives = 112/283 (39%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V+W K+G ++ ++ + G L ++ D G YS
Sbjct: 996 AGASATLSCEV-AQAQTEVMWYKDGKKLSSSL-KVHVEAKGCRRRLVVQQAGKTDAGDYS 1053
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ ++ RL + + ++ + + E AE A
Sbjct: 1054 CEA---RGQRVSF-RLHITEPKMMFAKEQSVHNEVQAE-------------------AGA 1090
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 1091 SAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAG 1149
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
VS H + KG+ A E E + G +S V A P VTWY+
Sbjct: 1150 GQR--VSFHLHITEPKGV---FAKEQSVHNE--VQAEAGTTAMLSCEV-AQPQTEVTWYK 1201
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + + L + V DAG Y+C A +
Sbjct: 1202 DGKKLSSSSKVRMEV-KGCTRRLVVQQVGKADAGEYSCEAGGQ 1243
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/178 (26%), Positives = 74/178 (41%), Gaps = 14/178 (7%)
Query: 2591 TRKP-VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
T KP VFS LTD T EG + L C S+ D V W ++G L + +
Sbjct: 3092 TEKPSVFSRELTDATITEGEDLTLVCET-STCDIPVCWTKDGKTLRGSARCQLSHEGHRA 3150
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
L + A DS Y C E G +S+ ++V+ A P+ F +++D L
Sbjct: 3151 QLLITGATLQDSGRYKC----EAGGACSSSIVRVH----ARPV--RFQEALKDLEVLEGG 3200
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + P + W + + +Y + + L + N P+DSG Y+C
Sbjct: 3201 AATLRCVLSSVAAP-VKWCYGNNVLRPGDKY-SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 54.0 bits (124), Expect = 9e-06
Identities = 65/301 (21%), Positives = 117/301 (38%), Gaps = 40/301 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + VTWY++G L + K R ++ L V +D+ EY
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S L + +R A L C + Q +
Sbjct: 1237 SC----EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTE---AGASATLSCEV-AQAQTE 1288
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + A + +L + D+G YTC+A +++ ++
Sbjct: 1289 VTWYKDGKKLSSSSKVR-IEAAGCMRQLVVQQAGQADAGEYTCEAGG----QRLSFHLD- 1342
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
V+ K A++ L R+ Q G L E+ T V
Sbjct: 1343 -----------VSEPKAVFAKEQLAHRK---------VQAEAGAIATLSCEVAQAQTEVT 1382
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
W ++G+ ++ + R+ L + + ++G Y+C A G ++ ++ V +
Sbjct: 1383 WYKDGKKLSSSSK-VRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAE 1437
Query: 2905 P 2905
P
Sbjct: 1438 P 1438
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGL 2648
S PVF T L ++ +G V C V P+V W+++G LL+ Y + G
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 2649 ITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
L + VP+D Y C EN G ST A L+V
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 52.4 bits (120), Expect = 3e-05
Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC ++ S +L V E + + R+ A L C + Q +
Sbjct: 1605 SCKAGDQR----LSFHLHV---AEPKVVFAKEQPAHREVQAEAGASATLSCEV-AQAQTE 1656
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+TW+KD K++ S + + RL + ++G Y+C+A
Sbjct: 1657 VTWYKDGKKLSSSSKVRV-EAVGCTRRLVVQQAGQAEAGEYSCEA 1700
Score = 52.0 bits (119), Expect = 4e-05
Identities = 75/289 (25%), Positives = 115/289 (39%), Gaps = 47/289 (16%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+TA L C + K P V W K GHE + R + + +G C L I+ + + D G YSC
Sbjct: 3728 GDTATLWCELS-KAAP-VEWRK-GHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSC 3784
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R + P +F ++++ +
Sbjct: 3785 VC----GQERTSATLTV---RAL-------------------PARFIEDVKNQEAREGAT 3818
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I ++ D G Y
Sbjct: 3819 AVLQCELSKAAP--VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEY------ 3870
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL--HEGDELRISAVVEAYPSVGVTWY 3302
SC CG AP+ EPL L EG + + + P+ V W
Sbjct: 3871 -----SCVCGQERTSATLTVRAPQ-PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWS 3923
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
+ G++L+ + R L + EL L + D G YTCT ++ A+
Sbjct: 3924 KGGLQLQANGRREPRL-QGCTAELVLQDLQREDTGEYTCTCGSQATSAT 3971
Score = 51.2 bits (117), Expect = 6e-05
Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D A E +C +S D V W NG+ L N + TL + + +
Sbjct: 2564 LQDAEATEEGWASFSCE-LSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRA 2622
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ V + +STSA L+V P F +++ D L L+C +
Sbjct: 2623 DAG----IVRASSLKVSTSARLEVRVK------PVVFLKALDDLSAEERGTLALQCEV-S 2671
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
P + W KD Q+ +Y + A G L + + +PED+G YTC
Sbjct: 2672 DPEAHVVWRKDGVQLGPSDKYDFLHTA-GTRGLVVHDVSPEDAGLYTC 2718
Score = 51.2 bits (117), Expect = 6e-05
Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 17/196 (8%)
Query: 2575 EARSVISEKRTLSRNSTR--KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV 2632
E V ++RT + + R +PVF L A EGS L C +S TV W + G+
Sbjct: 3869 EYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGL 3927
Query: 2633 LLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPI 2692
L + +L L + + D+ EY+CT G+ +TSA L V A+P+
Sbjct: 3928 QLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTV----TAAPV 3979
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCR 2751
F R ++ + E C + + W K Q+ +YQ + DG
Sbjct: 3980 --RFLRELQHQ-EVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQ--MVQDGAAAE 4034
Query: 2752 LAIDNPTPEDSGTYTC 2767
L + ED+G YTC
Sbjct: 4035 LLVRGVEQEDAGDYTC 4050
Score = 50.4 bits (115), Expect = 1e-04
Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRL 2752
P F+ + DT + L LEC + + + W KD ++ +DGR+ L DG C L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL-TDGRHHHIDQLGDGTCSL 4956
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITH--FVNFTGRESQ 2790
I D+G YTC+ N Q+TH V +G ES+
Sbjct: 4957 LITGLDRADAGCYTCQVSNKF--GQVTHSACVVVSGSESE 4994
Score = 50.0 bits (114), Expect = 1e-04
Identities = 40/140 (28%), Positives = 57/140 (40%), Gaps = 22/140 (15%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG R+S V P W +DG + RR ++ D L + D G+YT
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDT 3400
CTASN VG+ +S V VV P VP+ K + + E RE ++
Sbjct: 311 CTASNLVGQTYSSVLV---------------VVREPAVPFKK------RLQDLEVREKES 349
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
CE V P + W ++
Sbjct: 350 ATFLCE-VPQPSTEAAWFKE 368
Score = 50.0 bits (114), Expect = 1e-04
Identities = 84/361 (23%), Positives = 138/361 (38%), Gaps = 58/361 (16%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG TA L+C V +P V W K+G ++ + ++ + G L ++ + D G YS
Sbjct: 1180 AGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSS-KVRMEVKGCTRRLVVQQVGKADAGEYS 1237
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G +L + + V+ + + E R +A
Sbjct: 1238 CEA----GGQRVSFQLHITEPKAVFAKEQLVHNEV-------------------RTEAGA 1274
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y T
Sbjct: 1275 SATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY--TCE 1331
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+S H + K + A E + + G +S V A VTWY+
Sbjct: 1332 AGGQRLSFHLDVSEPKAV---FAKEQLAHRK--VQAEAGAIATLSCEV-AQAQTEVTWYK 1385
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
DG +L S + M + L + D G Y+C A + R S S V
Sbjct: 1386 DGKKLSSSSKVRMEAVGCTR-RLVVQQACQADTGEYSCEAGGQ--RLSFSLDV------- 1435
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLK 3423
+EP+ VV + + P +E +A+ G + + CE V + +V W +D K
Sbjct: 1436 -AEPK---VVFAKEQPVHRE---------VQAQAGASTTLSCE-VAQAQTEVMWYKDGKK 1481
Query: 3424 V 3424
+
Sbjct: 1482 L 1482
Score = 50.0 bits (114), Expect = 1e-04
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLE 2652
P+FS D A G ++L C V S +D W ++GV L D + + +L DG +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSA 2679
+ +D+ Y+C V N+ G ++ SA
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 49.6 bits (113), Expect = 2e-04
Identities = 51/177 (28%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLIT 2650
+PV F L D +EG L C V+SS V W Y N VL KY + ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGD-KYSLRQEGAMLE 3240
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L V N P DS YSC+ G +TSA L V + +P F +R+
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTV------TALPAQFIGKLRNKEATEGAT 3290
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + + P + W K + + RY +C L I D+ Y+C
Sbjct: 3291 ATLRCEL-SKAAP-VEWRKGSETLRDGDRY-CLRQDGAMCELQIRGLAMVDAAEYSC 3344
Score = 49.6 bits (113), Expect = 2e-04
Identities = 81/357 (22%), Positives = 133/357 (37%), Gaps = 47/357 (13%)
Query: 3001 GITPLNSFDAFNLKQ-GEEYHFRVTPRNRYGWGESS----QTSSSIGVGLAGDRPEFVDI 3055
G L D ++L+Q G ++ + GE S Q +S + + +P F +
Sbjct: 3836 GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREP 3895
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
L L+ G TA L C + +P VVW K G +++ GR + G L ++D+
Sbjct: 3896 LQS-LQAEEGSTATLQCELS-EPTATVVWSKGGLQLQAN-GRREPRLQGCTAELVLQDLQ 3952
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+D G Y+C T G +T A L V P +F L+
Sbjct: 3953 REDTGEYTC----TCGSQATSATLTVTA----------------------APVRFLRELQ 3986
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ V L C+ + V W K ++ + QD L + +D
Sbjct: 3987 HQEVDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA-VVEAY 3294
G Y ++G H + +R P+F L+ L + GD R+ + +A
Sbjct: 4046 GDYTC----DTG----HTQSMASLSVRV-PRPKFKTRLQSL-EQETGDIARLCCQLSDAE 4095
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
V W ++GV L + M + EL + + +D G Y C + AS
Sbjct: 4096 SGAVVQWLKEGVELHAGPKYEMR-SQGATRELLIHQLEAKDTGEYACVTGGQKTAAS 4151
Score = 49.2 bits (112), Expect = 3e-04
Identities = 38/166 (22%), Positives = 67/166 (40%), Gaps = 9/166 (5%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLL-DNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T EG +L+C V P W ++G L+ + + + L++L SD
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+CT N G +S + V P P F + ++D + C + QP
Sbjct: 308 LYTCTASNLVGQTYSSVLVVV-----REPAVP-FKKRLQDLEVREKESATFLCEV-PQPS 360
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ WFK++ ++ + +Y RL + N + +D Y C+
Sbjct: 361 TEAAWFKEETRLWASAKY-GIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 49.2 bits (112), Expect = 3e-04
Identities = 63/284 (22%), Positives = 113/284 (39%), Gaps = 38/284 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1362 AEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEY 1420
Query: 2665 SCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
SC E G S +L V P + P R+ A L C + Q
Sbjct: 1421 SC----EAGGQRLSFSLDVAEPKVVFAKEQPVH----REVQAQAGASTTLSCEV-AQAQT 1471
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++ W+KD K++ + + RL + +G Y+C+A + +++ ++
Sbjct: 1472 EVMWYKDGKKLSFSSKVR-MEAVGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLH 1526
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V K A++ SR + Q G + L E+ T V
Sbjct: 1527 ------------VAEPKAVFAKEQPASR---------EVQAEAGTSATLSCEVAQAQTEV 1565
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ L + + + ++G Y+C+A
Sbjct: 1566 TWYKDGKKLSSSSK-VRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 6120 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 6179
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 6180 YECELVNRLGSARASAELRI 6199
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 6123
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 6124 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 6162
Score = 47.6 bits (108), Expect = 8e-04
Identities = 69/288 (23%), Positives = 107/288 (37%), Gaps = 35/288 (12%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L+ AG +A L+C V + V W K+G ++ + ++ + G L ++ D
Sbjct: 899 KLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVCMEATGCTRRLVVQQAGQAD 956
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G YSCEA G L V + V+ D E AE
Sbjct: 957 AGEYSCEA----GGQRLSFHLDVKEPKVVFAKDQVAHSEVQAE----------------- 995
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
A L+C+V +V WYKDG+++ + + L + D G Y
Sbjct: 996 --AGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
AR + H + + + A E E + G +S V A
Sbjct: 1053 SCEARGQRVSFRLH---ITEP--KMMFAKEQSVHNE--VQAEAGASAMLSCEV-AQAQTE 1104
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
VTWY+DG +L S + M + + L L DAG Y+C A +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEV-KGCTRRLVLPQAGKADAGEYSCEAGGQ 1151
Score = 47.6 bits (108), Expect = 8e-04
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Query: 2664 YSCTVENENGAISTSA-NLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y + + G I A N + +P T R +RD + ++ VLEC++ +
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQV-SRAS 2317
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKA 2769
++ WFK +++ +Y+ ++DG+ R L I + ED TYTC A
Sbjct: 2318 AQVRWFKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Score = 47.6 bits (108), Expect = 8e-04
Identities = 55/221 (24%), Positives = 90/221 (40%), Gaps = 25/221 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAEN 2771
+ +++G P P++ WFKD + + + + + D + L I + T EDSG Y N
Sbjct: 5281 QLKVKGYPAPRLYWFKDGQPLTASAHIR---MTDKKILHTLEIISVTREDSGQYAAYISN 5337
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
++ + + G + + + + LE P +V +G +I
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPK--------KVKKGSSIT 5389
Query: 2832 LQVEIRGCPT-RVEWLREG--RSVTEVYRNA---RVFVEQGLYTLALSDVTETESGLYTC 2885
V++ G P V WLRE R V + + V ++L L DV G YTC
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 5449
Query: 2886 RAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
A +A G +A++ V G P V K+ LIS
Sbjct: 5450 IASNAAGQALCSASLHV------SGLPKVEEQEKVKEALIS 5484
Score = 46.8 bits (106), Expect = 0.001
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG A L+C V + V W K+G ++ + ++ + G L ++ D G YS
Sbjct: 1364 AGAIATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRMEAVGCTRRLVVQQACQADTGEYS 1421
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ +++ L V + V+ + + RE A QA
Sbjct: 1422 CEAG---GQRLSFS-LDVAEPKVVFAKEQPVHREVQA-------------------QAGA 1458
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V WYKDG+++ + + L + G Y A
Sbjct: 1459 STTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA- 1516
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
S +S H + K + A P + G +S V A VTWY+
Sbjct: 1517 -GSQRLSFHLHVAEPKAVFAKEQPA-----SREVQAEAGTSATLSCEV-AQAQTEVTWYK 1569
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + L + DAG Y+C A ++
Sbjct: 1570 DGKKLSSSSKVRMEAVGCTR-RLVVQEAGQADAGEYSCKAGDQ 1611
Score = 46.4 bits (105), Expect = 0.002
Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 22/224 (9%)
Query: 2570 SKAFSEARSVISEKRTLSRNST----RKPVFSTFLTDRTAVEGSRV-KLTCSVISSSDPT 2624
S ++ A+ +S + ST + P L D G+R+ K V P
Sbjct: 5232 SSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPR 5291
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+ W+++G L R L TLE+++ DS +Y+ + N GA +SA L V
Sbjct: 5292 LYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Query: 2685 PSFEASP----------IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI 2734
E +PP + + ++ G+P+P + W +++ +
Sbjct: 5352 GPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 2735 ------PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
P Y A + +D + GTYTC A N+
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLD-VGRQHQGTYTCIASNA 5454
Score = 46.0 bits (104), Expect = 0.002
Identities = 66/285 (23%), Positives = 112/285 (39%), Gaps = 40/285 (14%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K + L V A +D+ EY
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L V E + + + A L C + Q +
Sbjct: 961 SC----EAGGQRLSFHLDVK---EPKVVFAKDQVAHSEVQAEAGASATLSCEV-AQAQTE 1012
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ W+KD K++ S + A G RL + D+G Y+C+A
Sbjct: 1013 VMWYKDGKKLSSS--LKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA-------------- 1056
Query: 2784 FTGRESQVSPNV-VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTR 2842
R +VS + +T K A++ +V + Q G + L E+ T
Sbjct: 1057 ---RGQRVSFRLHITEPKMMFAKEQ---------SVHNEVQAEAGASAMLSCEVAQAQTE 1104
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
V W ++G+ ++ + + V+ L L + ++G Y+C A
Sbjct: 1105 VTWYKDGKKLSSSSK-VGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Score = 46.0 bits (104), Expect = 0.002
Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 36/302 (11%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S +D +W R+G+ + + TL + P DS E + T
Sbjct: 2100 LSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG----VHT 2155
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
SA L V + +P +F+R ++D + ++ LEC + +P + W KD ++ +
Sbjct: 2156 SARLVV------TELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRA- 2207
Query: 2738 GRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
G+ A A G CR L I D G Y C A ++ Q + V GR + V
Sbjct: 2208 GKTMAI-AAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRV 2262
Query: 2797 TAE---KTRIARQSLESRRP--------HFGNVLTDYQVARGGTIGLQVEIRGCPTRVEW 2845
AE + + ++ ESR L D L+ ++ +V W
Sbjct: 2263 LAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRW 2322
Query: 2846 LREGRSVTEVYRNARVFVEQGLY-TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
+ + + + V GLY L +SDV + YTC A G+V +A V +
Sbjct: 2323 FKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEE 2376
Query: 2905 PS 2906
S
Sbjct: 2377 QS 2378
Score = 46.0 bits (104), Expect = 0.002
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 15/168 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L ++ A EG+ L C +S + P V W + L + +Y + + L++
Sbjct: 3280 LRNKEATEGATATLRCE-LSKAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMV 3337
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+AEYSC E TSA+L + P+P F +R + L C +
Sbjct: 3338 DAAEYSCVCGEER----TSASLTI------RPMPAHFIGRLRHQESIEGATATLRCEL-S 3386
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ P + W K + + DG + VC L I D+G Y+C
Sbjct: 3387 KAAP-VEWRKGRESL-RDGDRHSLRQDGAVCELQICGLAVADAGEYSC 3432
Score = 45.6 bits (103), Expect = 0.003
Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 11/188 (5%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISS-SDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+P F T L G +L C + + S V W + GV L KY + L
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATREL 4126
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ D+ EY+C G T+A+L+V P T R + D A+ ++
Sbjct: 4127 LIHQLEAKDTGEYACV----TGGQKTAASLRV-----TEP-EVTIVRGLVDAEVTADEDV 4176
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C + + W + S+ + + L + TPED+GT + N
Sbjct: 4177 EFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGN 4236
Query: 2772 SVWTDQIT 2779
+ Q+T
Sbjct: 4237 HASSAQLT 4244
Score = 45.2 bits (102), Expect = 0.004
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 13/184 (7%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN 2655
F + L+ A EG C V+S SD V W+R+G LL K+ +L + +
Sbjct: 1901 FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISD 1959
Query: 2656 AVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLEC 2715
V D+ + TVE E GA S+SA L+V + P F + + + + LE
Sbjct: 1960 LVLEDAGQ--ITVEAE-GA-SSSAALRVREA------PVLFKKKLEPQTVEERSSVTLEV 2009
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +P P++ W ++ + + G+ + RL + N D G + C+ +
Sbjct: 2010 ELT-RPWPELRWTRNATAL-APGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ 2067
Query: 2776 DQIT 2779
++T
Sbjct: 2068 AKLT 2071
Score = 45.2 bits (102), Expect = 0.004
Identities = 51/205 (24%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 2569 RSKAFSEARSVISEKRTLSRNST-----RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP 2623
R A S+A V+ R L+ ++ R L D+ G V+L C + + P
Sbjct: 2797 REAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2624 TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
V W ++ + KY + L + A D+ EY+C VE A ++A+L V
Sbjct: 2857 -VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE----ASKSTASLHV 2911
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
FT + + + V C+ P +TW K ++ + G++Q
Sbjct: 2912 EEKANC------FTEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQP- 2963
Query: 2744 YLADGV-CRLAIDNPTPEDSGTYTC 2767
+G+ RL I DS TYTC
Sbjct: 2964 -SQEGLTLRLTISALEKADSDTYTC 2987
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 6097 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 6156 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 44.8 bits (101), Expect = 0.006
Identities = 49/192 (25%), Positives = 79/192 (41%), Gaps = 19/192 (9%)
Query: 2579 VISEKRTLSRNSTRKPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
V ++RT S T + + + F+ D + A EG+ L C ++S+ P V W + L
Sbjct: 3521 VCGQERT-SATLTIRALPARFIEDVKNQEAREGATAVLQCE-LNSAAP-VEWRKGSETLR 3577
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT 2695
+ +Y + L++ +D+ EYSC E TSA L V +P
Sbjct: 3578 DGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQER----TSAMLTV------RALPIK 3627
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
FT +R+ VL C + + + W+K + + DG + C L I
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETL-RDGDRHSLRQDGARCELQIR 3684
Query: 2756 NPTPEDSGTYTC 2767
ED+G Y C
Sbjct: 3685 GLVAEDAGEYLC 3696
Score = 44.8 bits (101), Expect = 0.006
Identities = 19/66 (28%), Positives = 35/66 (53%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+VE+ + +T P +PP + + P+F+ + ++ E ++G V +C V G P P
Sbjct: 5097 RVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPS 5156
Query: 3415 VYWLRD 3420
V W +D
Sbjct: 5157 VRWFKD 5162
Score = 43.6 bits (98), Expect = 0.013
Identities = 68/284 (23%), Positives = 108/284 (38%), Gaps = 39/284 (13%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V W K+G ++ + ++ + G L ++ + G YS
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRVEAVGCTRRLVVQQAGQAEAGEYS 1697
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G RL V E + ++ ER E P D
Sbjct: 1698 CEA----GGQQLSFRLQVA------ELEPQIS-ERPCRRE----PLVVKEHED------- 1735
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
+ LT + V+W KDG E+ KR HTL + + D +Y
Sbjct: 1736 -IILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRV- 1793
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG-VTWY 3302
GA + V++ VA +FC LEP+ G ++ E P+ V W
Sbjct: 1794 ---GAEGQDFPVQVEE-----VAAKFCRLLEPVCGELGG---TVTLACELSPACAEVVWR 1842
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+LR +R M + + L + + DAG Y C + ++
Sbjct: 1843 CGNTQLRVGKRFQMVAEGPVR-SLTVLGLRAEDAGEYVCESRDD 1885
Score = 43.2 bits (97), Expect = 0.017
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 32/226 (14%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V+W KDG + + L + DD G+YE +R G ++ +
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAYQLSV--- 791
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+G+ ++ + + + G EA+ V V WY+DG+ L S +
Sbjct: 792 QGLARFLHKDMAGSC--VDAVAGGPAQFECETSEAH--VHVHWYKDGMELGHSGERFLQE 847
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
D + L A VT +D G Y+C VG S ++ V SEP+ V
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV------SEPK---------V 888
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
++KE + RK +A G + + CE V + +V W +D K+
Sbjct: 889 VFAKEQLARRK---LQAEAGASATLSCE-VAQAQTEVTWYKDGKKL 930
Score = 43.2 bits (97), Expect = 0.017
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 14/174 (8%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E + LT ++ + S TVTW ++GV + ++ TL V A DSA YSC
Sbjct: 1732 EHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
V E + +P + + F R + + L C + ++
Sbjct: 1792 RVGAEG---------QDFP-VQVEEVAAKFCRLLEPVCGELGGTVTLACEL-SPACAEVV 1840
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
W + Q+ R+Q +A+G R L + ED+G Y C++ + + Q+T
Sbjct: 1841 WRCGNTQLRVGKRFQ--MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLT 1892
Score = 42.7 bits (96), Expect = 0.022
Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 14/187 (7%)
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR-MTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E L C + +P V W+K+G VE AG+ M G LTI D+G Y C
Sbjct: 2181 EKVTLECELS-RPNVDVRWLKDG--VELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC 2237
Query: 3125 EATNTHGKAS------TYA---RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+A + AS TY R + D + A+ R+ + P LR
Sbjct: 2238 DAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR 2297
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D+ + L CQV +V W+K +E+ + D + L I+ + +D
Sbjct: 2298 DKIAMEKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDE 2356
Query: 3236 GVYEVTA 3242
Y A
Sbjct: 2357 DTYTCDA 2363
Score = 42.3 bits (95), Expect = 0.030
Identities = 67/274 (24%), Positives = 110/274 (40%), Gaps = 43/274 (15%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S VTW ++G L KY + G L V + D+ Y C + G I+
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAY 787
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
+++ F + S D +A EC + + W+KD ++
Sbjct: 788 QLSVQGLARF----LHKDMAGSCVDA--VAGGPAQFECE-TSEAHVHVHWYKDGMELGHS 840
Query: 2738 GRYQAFYLAD-GV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNV 2795
G + F D G RL T +D GTY+C+ V D V+F R S+ P V
Sbjct: 841 G--ERFLQEDVGTRHRLVAATVTRQDEGTYSCR----VGEDS----VDFRLRVSE--PKV 888
Query: 2796 VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEV 2855
V A K ++AR+ L Q G + L E+ T V W ++G+ ++
Sbjct: 889 VFA-KEQLARRKL--------------QAEAGASATLSCEVAQAQTEVTWYKDGKKLSS- 932
Query: 2856 YRNARVFVEQGLYT--LALSDVTETESGLYTCRA 2887
+++V +E T L + + ++G Y+C A
Sbjct: 933 --SSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 42.3 bits (95), Expect = 0.030
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 17/170 (10%)
Query: 2606 VEGSRVKLTC--SVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+EG C S S+SDP + W G + + +++ L V A PSD+ E
Sbjct: 2748 LEGESCSFECVLSHESASDPAM-WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE 2806
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
+V +++ A+L V P + + D + ++ L C + P
Sbjct: 2807 VVFSVRG----LTSKASLIVRER------PAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENS 2772
+ W KD K I +Y + +G + L I + +D+G YTC+ E S
Sbjct: 2857 -VHWLKDRKAIRKSQKYDV--VCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/171 (26%), Positives = 64/171 (37%), Gaps = 13/171 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLITLEVLNAVP 2658
L D EGS C + ++ V W+ + L N+L G L +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
DS T+ E G SA L+V P F+R + D +L L C
Sbjct: 3071 KDSG----TIYFEAGDQRASAALRVTEK------PSVFSRELTDATITEGEDLTLVCETS 3120
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+P + W KD K + R Q + +L I T +DSG Y C+A
Sbjct: 3121 TCDIP-VCWTKDGKTLRGSARCQLSHEGHRA-QLLITGATLQDSGRYKCEA 3169
Score = 42.3 bits (95), Expect = 0.030
Identities = 74/294 (25%), Positives = 110/294 (37%), Gaps = 46/294 (15%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K G E R + + +G C L I +++ D G YSC
Sbjct: 3816 GATAVLQCELS-KAAP-VEWRK-GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC 3872
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R+ + P F L+ + +
Sbjct: 3873 VC----GQERTSATLTV----------------RAPQ------PVFREPLQSLQAEEGST 3906
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C+ + P V W K G ++ + RR Q T E+ +L R
Sbjct: 3907 ATLQCE-LSEPTATVVWSKGGLQLQANGRREPRL--QGCTAELVLQDLQ---------RE 3954
Query: 3245 NSGAVSCHCGLVVDKG-IRAYVAP-EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
++G +C CG + AP F L+ ++ EG + + V W
Sbjct: 3955 DTGEYTCTCGSQATSATLTVTAAPVRFLRELQH-QEVDEGGTAHLCCELSR-AGASVEWR 4012
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ ++L P + M D EL + V DAG YTC + AS S +V
Sbjct: 4013 KGSLQLFPCAKYQMVQD-GAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/174 (25%), Positives = 64/174 (36%), Gaps = 4/174 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
P + VV ++ V+L+W + Y+VE GA G R + P
Sbjct: 4526 PEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEV-KEGATGQWRLCH-ELVPGPECVV 4583
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANL 3070
L GE Y FRV G GE ++ + P ++ AGE +L
Sbjct: 4584 DGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSL 4643
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
V + V+W K G E + GR G L IK +D+G Y C
Sbjct: 4644 ELEVVAE-AGEVIWHK-GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 41.5 bits (93), Expect = 0.052
Identities = 66/284 (23%), Positives = 101/284 (35%), Gaps = 34/284 (11%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+AG A C V V W K+G E+ R + G L + DEG Y
Sbjct: 810 VAGGPAQFECETSEAHVH-VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTY 868
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
SC G+ S RL V + V+ + +R+ AE A
Sbjct: 869 SCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQAE-------------------AG 905
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 906 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+S H + K + A + E + G +S V A V WY
Sbjct: 965 --GGQRLSFHLDV---KEPKVVFAKDQVAHSE--VQAEAGASATLSCEV-AQAQTEVMWY 1016
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+DG +L S + + + + L + DAG Y+C A +
Sbjct: 1017 KDGKKLSSSLK-VHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Score = 41.1 bits (92), Expect = 0.068
Identities = 81/368 (22%), Positives = 141/368 (38%), Gaps = 59/368 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+++ AG + L+C V + V+W K+G ++ + ++ + G L ++
Sbjct: 1451 EVQAQAGASTTLSCEV-AQAQTEVMWYKDGKKLSFSS-KVRMEAVGCTRRLVVQQAGQAV 1508
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G YSCEA G L V + V+ + RE AE
Sbjct: 1509 AGEYSCEA----GSQRLSFHLHVAEPKAVFAKEQPASREVQAEAG--------------- 1549
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
AT L+C+V +V+WYKDG+++ + L + D G Y
Sbjct: 1550 TSAT----LSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A + +S H + K + A P + G +S V A
Sbjct: 1605 SCKAGDQR--LSFHLHVAEPKVVFAKEQPA-----HREVQAEAGASATLSCEV-AQAQTE 1656
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTWY+DG +L S + + ++ G L + +AG Y+C E G S +++
Sbjct: 1657 VTWYKDGKKLSSSSK--VRVEAVGCTRRLVVQQAGQAEAGEYSC----EAGGQQLSFRLQ 1710
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V EP+I + P +EP+ + +E + +I+ + V W
Sbjct: 1711 V----AELEPQI------SERPCRREPLVV--------KEHEDIILTATLATPSAATVTW 1752
Query: 3418 LRDFLKVR 3425
L+D +++R
Sbjct: 1753 LKDGVEIR 1760
Score = 41.1 bits (92), Expect = 0.068
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 8/126 (6%)
Query: 2690 SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK-ITWFKDDKQIPSDGRYQAFYLADG 2748
S IP TR + +VL C R P PK + W+KDD + +++ L
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFR--PAPKAVQWYKDDTPLSPSEKFK-MSLEGQ 2521
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
+ L I P D+G Y C+A ++ + ++T RE V+ + AE T S
Sbjct: 2522 MAELRILRLMPADAGVYRCQAGSAHSSTEVT----VEAREVTVTGPLQDAEATEEGWASF 2577
Query: 2809 ESRRPH 2814
H
Sbjct: 2578 SCELSH 2583
Score = 41.1 bits (92), Expect = 0.068
Identities = 43/181 (23%), Positives = 68/181 (37%), Gaps = 11/181 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D EG C + +S W GV L + G + L L+ V
Sbjct: 4256 LQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTL 4315
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+ A TV G S+ A LKV T R + + L E + EC++
Sbjct: 4316 EDAG---TVSFHVGTCSSEAQLKVTAK-------NTVVRGLENVEALEGGEALFECQLSQ 4365
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQI 2778
+ TW DD+ + + + + +G+ L + N P+DS T A + V + +
Sbjct: 4366 PEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFL 4425
Query: 2779 T 2779
T
Sbjct: 4426 T 4426
Score = 40.3 bits (90), Expect = 0.12
Identities = 92/365 (25%), Positives = 137/365 (37%), Gaps = 78/365 (21%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K GHE + R + + +G C L I+ + +D G Y C
Sbjct: 3640 GATAVLRCELS-KMAP-VEWWK-GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC 3696
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
GK T A L V R + P +F LR+
Sbjct: 3697 MC----GKERTSAMLTV---RAM-------------------PSKFIEGLRNEEATEGDT 3730
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I + D G Y
Sbjct: 3731 ATLWCELSKAAP--VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEY------ 3782
Query: 3245 NSGAVSCHCG---LVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
SC CG +RA A F +E + + E + V W
Sbjct: 3783 -----SCVCGQERTSATLTVRALPA-RF---IEDVKNQEAREGATAVLQCELSKAAPVEW 3833
Query: 3302 YRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ LR R +L +DG + EL + ++ D G Y+C G+ TS + V
Sbjct: 3834 RKGSETLRGGDR--YSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV-- 3885
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R P P +EP+ +S +A EG T ++CE + +P V W +
Sbjct: 3886 -------RAPQ-------PVFREPL-----QSLQAEEGSTATLQCE-LSEPTATVVWSKG 3925
Query: 3421 FLKVR 3425
L+++
Sbjct: 3926 GLQLQ 3930
Score = 39.5 bits (88), Expect = 0.21
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 3/135 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + V+ G L +I G PT +V W ++ + V R R+ + LY
Sbjct: 7 SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGAR-FRLAQDGDLY 65
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
L + D+ +SG Y CRA +A G + V + + + RP I + G
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREG 124
Query: 2929 EDINISFRTQGEPKP 2943
+ R G P+P
Sbjct: 125 SEATFRCRVGGSPRP 139
Score = 39.1 bits (87), Expect = 0.28
Identities = 68/307 (22%), Positives = 115/307 (37%), Gaps = 43/307 (14%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
KPV F L D +A E + L C V S + V W ++GV L KY G L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
V + P D+ Y+C V G+ T A ++V+ + T+ ++ L
Sbjct: 2704 VVHDVSPEDAGLYTCHV----GSEETRARVRVH------DLHVGITKRLKTMEVLEGESC 2753
Query: 2712 VLECRIRGQPL-PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
EC + + W K + S R+QA L + P D+G
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYI-LVVREAAPSDAGE------ 2806
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
V F+ R +++ E+ + LE D VA G +
Sbjct: 2807 -----------VVFSVRGLTSKASLIVRERPAAIIKPLE-----------DQWVAPGEDV 2844
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ E+ T V WL++ +++ + + V E + L + + ++G YTC ++
Sbjct: 2845 ELRCELSRAGTPVHWLKDRKAIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Query: 2891 HGNVDMN 2897
++
Sbjct: 2904 KSTASLH 2910
Score = 38.7 bits (86), Expect = 0.36
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P V W +DGV+L PS + L G L + V+ DAG+YTC +E RA
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDF-LHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRA 2727
Score = 37.9 bits (84), Expect = 0.64
Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
V WY+D L PS + M+L +GQ+ EL + + DAGVY C A + +ST VE
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSL--EGQMAELRILRLMPADAGVYRCQAGS--AHSSTEVTVE 2554
Score = 37.5 bits (83), Expect = 0.84
Identities = 13/41 (31%), Positives = 23/41 (56%)
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+S P F+ +P++ G + C++VG+P P V W +D
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKD 46
Score = 37.5 bits (83), Expect = 0.84
Identities = 46/178 (25%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+ +R + VQA +T V + W+ DG+ + + D HTL I
Sbjct: 611 PKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTI 670
Query: 3228 --APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
P +L G + A N S + G+ A P E L +LHE +L
Sbjct: 671 REVPASL-HGAQLKFVA--NGIESSIRMEVRAAPGLTAN-KPPAAAAREVLARLHEEAQL 726
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTA 3343
+A VTW +DG L P + + G+ L + V DAG+Y C +
Sbjct: 727 LAELSDQA---AAVTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECVS 780
Score = 36.7 bits (81), Expect = 1.5
Identities = 40/168 (23%), Positives = 66/168 (39%), Gaps = 14/168 (8%)
Query: 3185 VRLTCQVIGSPP-PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V L C++ SP +V W ++ KR + +L + +D G Y +R
Sbjct: 1826 VTLACEL--SPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESR 1883
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
++ S + V + ++ F GL + EG E VV V V W+R
Sbjct: 1884 DDH--TSAQLTVSVPRVVK------FMSGLSTVVA-EEGGEATFQCVVSP-SDVAVVWFR 1933
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
DG L+PS + ++ L ++ + DAG T A A+
Sbjct: 1934 DGALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSAA 1980
Score = 36.3 bits (80), Expect = 1.9
Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GE L C +P V W K+G + A R G L I + D GR
Sbjct: 3107 ITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA-RCQLSHEGHRAQLLITGATLQDSGR 3164
Query: 3122 YSCEA 3126
Y CEA
Sbjct: 3165 YKCEA 3169
Score = 35.9 bits (79), Expect = 2.6
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLL--DNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
EGS C V S P V+W ++G L + + R + + L + A P D Y
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 2665 SCTVENENGAISTSANLKV 2683
EN GA S +A L V
Sbjct: 183 EVRAENPLGAASAAAALVV 201
Score = 35.9 bits (79), Expect = 2.6
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 3050 PEFVDILPGQLKILA--GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
P V + G ++A G A C V V VVW ++G ++ SQ +G
Sbjct: 1896 PRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-AVVWFRDGALLQPSEKFAISQ-SGASH 1953
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
LTI D+ ++D G+ + EA A+ R A V
Sbjct: 1954 SLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Score = 35.5 bits (78), Expect = 3.4
Identities = 43/195 (22%), Positives = 73/195 (37%), Gaps = 19/195 (9%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
P L D+ V V L C++ + P V W KD + + ++ + + L
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLV 2884
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-EGDEL 3285
I +L D G Y + S H V + C E L L E
Sbjct: 2885 IRGASLKDAGEYTCEVEASKSTASLH------------VEEKANCFTEELTNLQVEEKGT 2932
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ +P+ VTW + + LR S + + L ++A+ D+ YTC
Sbjct: 2933 AVFTCKTEHPAATVTWRKGLLELRASGKH-QPSQEGLTLRLTISALEKADSDTYTC---- 2987
Query: 3346 EVGRASTSGKVEVIG 3360
++G+A + ++ V G
Sbjct: 2988 DIGQAQSRAQLLVQG 3002
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 6008 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 6056
Score = 34.3 bits (75), Expect = 7.9
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 2804 ARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFV 2863
AR + + F L D GT+ LQ E+ V W ++G + + +
Sbjct: 2638 ARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWS 2889
G L + DV+ ++GLYTC S
Sbjct: 2698 -AGTRGLVVHDVSPEDAGLYTCHVGS 2722
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 103 bits (246), Expect = 1e-20
Identities = 81/267 (30%), Positives = 109/267 (40%), Gaps = 16/267 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+F R + V L+CQ++G+P P+VSW KD + V R QD + L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD-KGIRAYVAPEFCCGLEPL-YKLHEGDEL 3285
L D G Y ARN G GL VD + A AP F L P ++ EG E
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFL--LRPTSIRVREGSEA 127
Query: 3286 RISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
V P V+W +DG RL P + + L + A RD G Y A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 3345 NEVGRASTSGK--VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR----KPRSSEAR-- 3396
N +G AS + V+ D S P + + +E M P S+ R
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTC 247
Query: 3397 ---EGDTVIIECEVVGDPKPDVYWLRD 3420
EG + C V G+PKP+ W +D
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKD 274
Score = 102 bits (244), Expect = 3e-20
Identities = 142/607 (23%), Positives = 224/607 (36%), Gaps = 61/607 (10%)
Query: 2802 RIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNAR 2860
++ ++ + P F + D + G + L+ + R WL++G +T+ +
Sbjct: 4887 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 4946
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPE 2920
+ G +L ++ + ++G YTC+ + G V +A V+V E
Sbjct: 4947 DQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSAC--------------VVVSGSE 4992
Query: 2921 KDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVL 2980
+ S G +++ +FR + + P E V ++S ++P+ A
Sbjct: 4993 SEAESSSGGELDDAFRRAARRLHRLFRTKSPAE---VSDEELFLSADEGPAEPEEPADWQ 5049
Query: 2981 AYKVESWLIGAEGGARW-VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
Y+ + I A +T A L G E R S +T +
Sbjct: 5050 TYREDEHFICIRFEALTEARQAVTRFQEMFA-TLGIGVEIKLVEQGPRRVEMCISKETPA 5108
Query: 3040 SIGVG------LAGDR-PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
+ L D P F+ L Q ++ G + C V G+P+P V W K+G +E
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQ-EVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE 5167
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--A 3150
E+ M ++ L I + D G Y C A N+ G +ST A L V T ++ A
Sbjct: 5168 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAA 5227
Query: 3151 DAKLKRE--------RSAEVEGDYP-------PQFTMRLRDRRV-QATYPVRLTCQVIGS 3194
DA S E EG PQ LRD +V T + +V G
Sbjct: 5228 DATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY 5287
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
P P++ W+KDG+ + + HTLEI +D G Y N GA
Sbjct: 5288 PAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSAR 5347
Query: 3255 LVV----------DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
L+V + + P K+ +G + S VE P V W R+
Sbjct: 5348 LLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLRE 5407
Query: 3305 ----GVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
GV + P Q L L V + G YTC ASN G+A S + V
Sbjct: 5408 EAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS 5467
Query: 3360 GTDQTSE 3366
G + E
Sbjct: 5468 GLPKVEE 5474
Score = 85.4 bits (202), Expect = 3e-15
Identities = 91/309 (29%), Positives = 127/309 (41%), Gaps = 23/309 (7%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNG 3104
A P F+ + P +++ G A C V G P P V W K+G + E G R+ + G
Sbjct: 106 AEQAPHFL-LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELG 164
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEAD---------AKLK 3155
L I+ D G Y A N G AS A L V +D + A L+
Sbjct: 165 EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224
Query: 3156 RERSA-EVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR 3214
R R A EG + R V RL+C V G P P+ W KDG+ V +R
Sbjct: 225 RRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRH 284
Query: 3215 NKYQDEQFH-TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
Y+D Q + L+I D G+Y TA N G LVV +R P F L
Sbjct: 285 VVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVV---VREPAVP-FKKRL 339
Query: 3274 EPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVT 3332
+ L ++ E + V PS W+++ RL S A ++ +G + L + V+
Sbjct: 340 QDL-EVREKESATFLCEV-PQPSTEAAWFKEETRLWAS--AKYGIEEEGTERRLTVRNVS 395
Query: 3333 TRDAGVYTC 3341
D VY C
Sbjct: 396 ADDDAVYIC 404
Score = 84.2 bits (199), Expect = 7e-15
Identities = 67/204 (32%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + G+ A L+C + G P P V W K+ V A +Q +G LTI D+ +
Sbjct: 16 PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ-DGDLYRLTILDLAL 74
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G+Y C A N G+A L V +A+A + P F +R
Sbjct: 75 GDSGQYVCRARNAIGEAFAAVGLQV-------DAEAAC---------AEQAPHFLLRPTS 118
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQD-EQFHTLEIAPTNLDD 3234
RV+ C+V GSP P VSW KDG + D R + ++ + L I D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD 3258
GG YEV A N GA S LVVD
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVD 202
Score = 84.2 bits (199), Expect = 7e-15
Identities = 75/285 (26%), Positives = 120/285 (42%), Gaps = 27/285 (9%)
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
PS S P F +++ + +C + GQP+P + WFKD K + D Y
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENS--VWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
G +L I P D G Y C AENS V + + V+ T + + + +
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 2803 IARQSLESRR-------------PHFGNVLTDYQVARGGTIG-LQVEIRGCPT-RVEWLR 2847
A+ L SR P L D QVA G + Q++++G P R+ W +
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 2848 EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD 2907
+G+ +T + R+ ++ L+TL + VT +SG Y +A G +A + V P +
Sbjct: 5297 DGQPLT-ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 2908 LDGKPAVIVGR---PEKDI------LISVGEDINISFRTQGEPKP 2943
+ KPA V P + + + G I S + +G P P
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVP 5400
Score = 79.8 bits (188), Expect = 2e-13
Identities = 70/310 (22%), Positives = 118/310 (38%), Gaps = 12/310 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L+C ++ + P V+W ++ + ++R L L +L+ DS +Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N G + L+V + P F +E CR+ G P P ++W
Sbjct: 84 ARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSW 143
Query: 2728 FKDDKQI--PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH--FVN 2783
KD +++ P R + L + L I P D GTY +AEN + V+
Sbjct: 144 SKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVD 202
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV------LTDYQVARGGTIGLQVEIR 2837
++ P TA ++ E+ R V G L +
Sbjct: 203 SDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVT 262
Query: 2838 GCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDM 2896
G P W ++G+ VTE R+ Q + L + +++ GLYTC A + G
Sbjct: 263 GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYS 322
Query: 2897 NAAITVVQPS 2906
+ + V +P+
Sbjct: 323 SVLVVVREPA 332
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 6125
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 6186 NRLGSARASAELRI 6199
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 6124
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 2770 EN 2771
N
Sbjct: 6185 VN 6186
Score = 68.5 bits (160), Expect = 4e-10
Identities = 107/437 (24%), Positives = 165/437 (37%), Gaps = 49/437 (11%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ L C+I G P P+++W KD + + + R++ D + RL I + DSG Y C+A
Sbjct: 26 DATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLTILDLALGDSGQYVCRA 84
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N++ F QV AE+ PHF T +V G
Sbjct: 85 RNAIGEA-------FAAVGLQVDAEAACAEQA-----------PHFLLRPTSIRVREGSE 126
Query: 2830 IGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQ--GLYTLALSDVTETESGLYTCR 2886
+ + G P V W ++GR + E RV VE+ L + + G Y R
Sbjct: 127 ATFRCRVGGSPRPAVSWSKDGRRLGEP-DGPRVRVEELGEASALRIRAARPRDGGTYEVR 185
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI--LISVGEDINISFRTQGEPKPK 2944
A + G AA+ V D A RP L++ + + R +G P
Sbjct: 186 AENPLGAASAAAALVV------DSDAADTASRPGTSTAALLAHLQRRREAMRAEGAP--- 236
Query: 2945 AVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP 3004
A P C V G + + +P+ P +K + L+ EG V
Sbjct: 237 ASPPSTGTRTCTVTEGKHARLSCYVTGEPK---PETVWKKDGQLV-TEGRRHVVYEDAQE 292
Query: 3005 LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
KQ + + T N G QT SS+ V + F L L++
Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVG-----QTYSSVLVVVREPAVPFKKRLQ-DLEVRE 346
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E+A C V +P W K + A + + G + LT+++++ DD+ Y C
Sbjct: 347 KESATFLCEVP-QPSTEAAWFKEETRLWASA-KYGIEEEGTERRLTVRNVSADDDAVYIC 404
Query: 3125 EATNTHGKASTYARLAV 3141
E T + T A LAV
Sbjct: 405 E---TPEGSRTVAELAV 418
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 6088 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 6124
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 3243 RNNSGA 3248
N G+
Sbjct: 6185 VNRLGS 6190
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 6088 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 6125
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 6126 QFTCTIEGAPYPQIRWYKD 6144
Score = 60.1 bits (139), Expect = 1e-07
Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
V+ YP+ + W++DG L S MT D+ L + +VT D+G Y SN +G A
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+S ++ V G D+ E + V VP P + + + ++G ++ +V G
Sbjct: 5343 YSSARLLVRGPDEPEE-KPASDVHEQLVP----PRMLERFTPKKVKKGSSITFSVKVEGR 5397
Query: 3411 PKPDVYWLRD 3420
P P V+WLR+
Sbjct: 5398 PVPTVHWLRE 5407
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 6013 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 6072 LILDSLTGVDSGQYMCFAASA 6092
Score = 56.8 bits (131), Expect = 1e-06
Identities = 62/283 (21%), Positives = 114/283 (40%), Gaps = 36/283 (12%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K ++ L + A +D+ EY
Sbjct: 1086 AEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEY 1144
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L + + ++ A +L C + QP +
Sbjct: 1145 SC----EAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAE---AGTTAMLSCEV-AQPQTE 1196
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + + RL + D+G Y+C+A + Q+ H
Sbjct: 1197 VTWYKDGKKLSSSSKVR-MEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQL-H---- 1250
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+T K A++ L V + + G + L E+ T V
Sbjct: 1251 -----------ITEPKAVFAKEQL---------VHNEVRTEAGASATLSCEVAQAQTEVT 1290
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ + L + + ++G YTC A
Sbjct: 1291 WYKDGKKLSSSSK-VRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 56.0 bits (129), Expect = 2e-06
Identities = 70/283 (24%), Positives = 112/283 (39%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V+W K+G ++ ++ + G L ++ D G YS
Sbjct: 996 AGASATLSCEV-AQAQTEVMWYKDGKKLSSSL-KVHVEAKGCRRRLVVQQAGKTDAGDYS 1053
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ ++ RL + + ++ + + E AE A
Sbjct: 1054 CEA---RGQRVSF-RLHITEPKMMFAKEQSVHNEVQAE-------------------AGA 1090
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 1091 SAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAG 1149
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
VS H + KG+ A E E + G +S V A P VTWY+
Sbjct: 1150 GQR--VSFHLHITEPKGV---FAKEQSVHNE--VQAEAGTTAMLSCEV-AQPQTEVTWYK 1201
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + + L + V DAG Y+C A +
Sbjct: 1202 DGKKLSSSSKVRMEV-KGCTRRLVVQQVGKADAGEYSCEAGGQ 1243
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/178 (26%), Positives = 74/178 (41%), Gaps = 14/178 (7%)
Query: 2591 TRKP-VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
T KP VFS LTD T EG + L C S+ D V W ++G L + +
Sbjct: 3092 TEKPSVFSRELTDATITEGEDLTLVCET-STCDIPVCWTKDGKTLRGSARCQLSHEGHRA 3150
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
L + A DS Y C E G +S+ ++V+ A P+ F +++D L
Sbjct: 3151 QLLITGATLQDSGRYKC----EAGGACSSSIVRVH----ARPV--RFQEALKDLEVLEGG 3200
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + P + W + + +Y + + L + N P+DSG Y+C
Sbjct: 3201 AATLRCVLSSVAAP-VKWCYGNNVLRPGDKY-SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 54.0 bits (124), Expect = 9e-06
Identities = 65/301 (21%), Positives = 117/301 (38%), Gaps = 40/301 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + VTWY++G L + K R ++ L V +D+ EY
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S L + +R A L C + Q +
Sbjct: 1237 SC----EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTE---AGASATLSCEV-AQAQTE 1288
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + A + +L + D+G YTC+A +++ ++
Sbjct: 1289 VTWYKDGKKLSSSSKVR-IEAAGCMRQLVVQQAGQADAGEYTCEAGG----QRLSFHLD- 1342
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
V+ K A++ L R+ Q G L E+ T V
Sbjct: 1343 -----------VSEPKAVFAKEQLAHRK---------VQAEAGAIATLSCEVAQAQTEVT 1382
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
W ++G+ ++ + R+ L + + ++G Y+C A G ++ ++ V +
Sbjct: 1383 WYKDGKKLSSSSK-VRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAE 1437
Query: 2905 P 2905
P
Sbjct: 1438 P 1438
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGL 2648
S PVF T L ++ +G V C V P+V W+++G LL+ Y + G
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 2649 ITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
L + VP+D Y C EN G ST A L+V
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 52.4 bits (120), Expect = 3e-05
Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC ++ S +L V E + + R+ A L C + Q +
Sbjct: 1605 SCKAGDQR----LSFHLHV---AEPKVVFAKEQPAHREVQAEAGASATLSCEV-AQAQTE 1656
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+TW+KD K++ S + + RL + ++G Y+C+A
Sbjct: 1657 VTWYKDGKKLSSSSKVRV-EAVGCTRRLVVQQAGQAEAGEYSCEA 1700
Score = 52.0 bits (119), Expect = 4e-05
Identities = 75/289 (25%), Positives = 115/289 (39%), Gaps = 47/289 (16%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+TA L C + K P V W K GHE + R + + +G C L I+ + + D G YSC
Sbjct: 3728 GDTATLWCELS-KAAP-VEWRK-GHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSC 3784
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R + P +F ++++ +
Sbjct: 3785 VC----GQERTSATLTV---RAL-------------------PARFIEDVKNQEAREGAT 3818
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I ++ D G Y
Sbjct: 3819 AVLQCELSKAAP--VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEY------ 3870
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL--HEGDELRISAVVEAYPSVGVTWY 3302
SC CG AP+ EPL L EG + + + P+ V W
Sbjct: 3871 -----SCVCGQERTSATLTVRAPQ-PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWS 3923
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
+ G++L+ + R L + EL L + D G YTCT ++ A+
Sbjct: 3924 KGGLQLQANGRREPRL-QGCTAELVLQDLQREDTGEYTCTCGSQATSAT 3971
Score = 51.2 bits (117), Expect = 6e-05
Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D A E +C +S D V W NG+ L N + TL + + +
Sbjct: 2564 LQDAEATEEGWASFSCE-LSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRA 2622
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ V + +STSA L+V P F +++ D L L+C +
Sbjct: 2623 DAG----IVRASSLKVSTSARLEVRVK------PVVFLKALDDLSAEERGTLALQCEV-S 2671
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
P + W KD Q+ +Y + A G L + + +PED+G YTC
Sbjct: 2672 DPEAHVVWRKDGVQLGPSDKYDFLHTA-GTRGLVVHDVSPEDAGLYTC 2718
Score = 51.2 bits (117), Expect = 6e-05
Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 17/196 (8%)
Query: 2575 EARSVISEKRTLSRNSTR--KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV 2632
E V ++RT + + R +PVF L A EGS L C +S TV W + G+
Sbjct: 3869 EYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGL 3927
Query: 2633 LLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPI 2692
L + +L L + + D+ EY+CT G+ +TSA L V A+P+
Sbjct: 3928 QLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTV----TAAPV 3979
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCR 2751
F R ++ + E C + + W K Q+ +YQ + DG
Sbjct: 3980 --RFLRELQHQ-EVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQ--MVQDGAAAE 4034
Query: 2752 LAIDNPTPEDSGTYTC 2767
L + ED+G YTC
Sbjct: 4035 LLVRGVEQEDAGDYTC 4050
Score = 50.4 bits (115), Expect = 1e-04
Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRL 2752
P F+ + DT + L LEC + + + W KD ++ +DGR+ L DG C L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL-TDGRHHHIDQLGDGTCSL 4956
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITH--FVNFTGRESQ 2790
I D+G YTC+ N Q+TH V +G ES+
Sbjct: 4957 LITGLDRADAGCYTCQVSNKF--GQVTHSACVVVSGSESE 4994
Score = 50.0 bits (114), Expect = 1e-04
Identities = 40/140 (28%), Positives = 57/140 (40%), Gaps = 22/140 (15%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG R+S V P W +DG + RR ++ D L + D G+YT
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDT 3400
CTASN VG+ +S V VV P VP+ K + + E RE ++
Sbjct: 311 CTASNLVGQTYSSVLV---------------VVREPAVPFKK------RLQDLEVREKES 349
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
CE V P + W ++
Sbjct: 350 ATFLCE-VPQPSTEAAWFKE 368
Score = 50.0 bits (114), Expect = 1e-04
Identities = 84/361 (23%), Positives = 138/361 (38%), Gaps = 58/361 (16%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG TA L+C V +P V W K+G ++ + ++ + G L ++ + D G YS
Sbjct: 1180 AGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSS-KVRMEVKGCTRRLVVQQVGKADAGEYS 1237
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G +L + + V+ + + E R +A
Sbjct: 1238 CEA----GGQRVSFQLHITEPKAVFAKEQLVHNEV-------------------RTEAGA 1274
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y T
Sbjct: 1275 SATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY--TCE 1331
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+S H + K + A E + + G +S V A VTWY+
Sbjct: 1332 AGGQRLSFHLDVSEPKAV---FAKEQLAHRK--VQAEAGAIATLSCEV-AQAQTEVTWYK 1385
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
DG +L S + M + L + D G Y+C A + R S S V
Sbjct: 1386 DGKKLSSSSKVRMEAVGCTR-RLVVQQACQADTGEYSCEAGGQ--RLSFSLDV------- 1435
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLK 3423
+EP+ VV + + P +E +A+ G + + CE V + +V W +D K
Sbjct: 1436 -AEPK---VVFAKEQPVHRE---------VQAQAGASTTLSCE-VAQAQTEVMWYKDGKK 1481
Query: 3424 V 3424
+
Sbjct: 1482 L 1482
Score = 50.0 bits (114), Expect = 1e-04
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLE 2652
P+FS D A G ++L C V S +D W ++GV L D + + +L DG +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSA 2679
+ +D+ Y+C V N+ G ++ SA
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 49.6 bits (113), Expect = 2e-04
Identities = 51/177 (28%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLIT 2650
+PV F L D +EG L C V+SS V W Y N VL KY + ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGD-KYSLRQEGAMLE 3240
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L V N P DS YSC+ G +TSA L V + +P F +R+
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTV------TALPAQFIGKLRNKEATEGAT 3290
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + + P + W K + + RY +C L I D+ Y+C
Sbjct: 3291 ATLRCEL-SKAAP-VEWRKGSETLRDGDRY-CLRQDGAMCELQIRGLAMVDAAEYSC 3344
Score = 49.6 bits (113), Expect = 2e-04
Identities = 81/357 (22%), Positives = 133/357 (37%), Gaps = 47/357 (13%)
Query: 3001 GITPLNSFDAFNLKQ-GEEYHFRVTPRNRYGWGESS----QTSSSIGVGLAGDRPEFVDI 3055
G L D ++L+Q G ++ + GE S Q +S + + +P F +
Sbjct: 3836 GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREP 3895
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
L L+ G TA L C + +P VVW K G +++ GR + G L ++D+
Sbjct: 3896 LQS-LQAEEGSTATLQCELS-EPTATVVWSKGGLQLQAN-GRREPRLQGCTAELVLQDLQ 3952
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+D G Y+C T G +T A L V P +F L+
Sbjct: 3953 REDTGEYTC----TCGSQATSATLTVTA----------------------APVRFLRELQ 3986
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ V L C+ + V W K ++ + QD L + +D
Sbjct: 3987 HQEVDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA-VVEAY 3294
G Y ++G H + +R P+F L+ L + GD R+ + +A
Sbjct: 4046 GDYTC----DTG----HTQSMASLSVRV-PRPKFKTRLQSL-EQETGDIARLCCQLSDAE 4095
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
V W ++GV L + M + EL + + +D G Y C + AS
Sbjct: 4096 SGAVVQWLKEGVELHAGPKYEMR-SQGATRELLIHQLEAKDTGEYACVTGGQKTAAS 4151
Score = 49.2 bits (112), Expect = 3e-04
Identities = 38/166 (22%), Positives = 67/166 (40%), Gaps = 9/166 (5%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLL-DNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T EG +L+C V P W ++G L+ + + + L++L SD
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+CT N G +S + V P P F + ++D + C + QP
Sbjct: 308 LYTCTASNLVGQTYSSVLVVV-----REPAVP-FKKRLQDLEVREKESATFLCEV-PQPS 360
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ WFK++ ++ + +Y RL + N + +D Y C+
Sbjct: 361 TEAAWFKEETRLWASAKY-GIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 49.2 bits (112), Expect = 3e-04
Identities = 63/284 (22%), Positives = 113/284 (39%), Gaps = 38/284 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1362 AEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEY 1420
Query: 2665 SCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
SC E G S +L V P + P R+ A L C + Q
Sbjct: 1421 SC----EAGGQRLSFSLDVAEPKVVFAKEQPVH----REVQAQAGASTTLSCEV-AQAQT 1471
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++ W+KD K++ + + RL + +G Y+C+A + +++ ++
Sbjct: 1472 EVMWYKDGKKLSFSSKVR-MEAVGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLH 1526
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V K A++ SR + Q G + L E+ T V
Sbjct: 1527 ------------VAEPKAVFAKEQPASR---------EVQAEAGTSATLSCEVAQAQTEV 1565
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ L + + + ++G Y+C+A
Sbjct: 1566 TWYKDGKKLSSSSK-VRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 6120 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 6179
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 6180 YECELVNRLGSARASAELRI 6199
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 6123
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 6124 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 6162
Score = 47.6 bits (108), Expect = 8e-04
Identities = 69/288 (23%), Positives = 107/288 (37%), Gaps = 35/288 (12%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L+ AG +A L+C V + V W K+G ++ + ++ + G L ++ D
Sbjct: 899 KLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVCMEATGCTRRLVVQQAGQAD 956
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G YSCEA G L V + V+ D E AE
Sbjct: 957 AGEYSCEA----GGQRLSFHLDVKEPKVVFAKDQVAHSEVQAE----------------- 995
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
A L+C+V +V WYKDG+++ + + L + D G Y
Sbjct: 996 --AGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
AR + H + + + A E E + G +S V A
Sbjct: 1053 SCEARGQRVSFRLH---ITEP--KMMFAKEQSVHNE--VQAEAGASAMLSCEV-AQAQTE 1104
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
VTWY+DG +L S + M + + L L DAG Y+C A +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEV-KGCTRRLVLPQAGKADAGEYSCEAGGQ 1151
Score = 47.6 bits (108), Expect = 8e-04
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Query: 2664 YSCTVENENGAISTSA-NLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y + + G I A N + +P T R +RD + ++ VLEC++ +
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQV-SRAS 2317
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKA 2769
++ WFK +++ +Y+ ++DG+ R L I + ED TYTC A
Sbjct: 2318 AQVRWFKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Score = 47.6 bits (108), Expect = 8e-04
Identities = 55/221 (24%), Positives = 90/221 (40%), Gaps = 25/221 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAEN 2771
+ +++G P P++ WFKD + + + + + D + L I + T EDSG Y N
Sbjct: 5281 QLKVKGYPAPRLYWFKDGQPLTASAHIR---MTDKKILHTLEIISVTREDSGQYAAYISN 5337
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
++ + + G + + + + LE P +V +G +I
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPK--------KVKKGSSIT 5389
Query: 2832 LQVEIRGCPT-RVEWLREG--RSVTEVYRNA---RVFVEQGLYTLALSDVTETESGLYTC 2885
V++ G P V WLRE R V + + V ++L L DV G YTC
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 5449
Query: 2886 RAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
A +A G +A++ V G P V K+ LIS
Sbjct: 5450 IASNAAGQALCSASLHV------SGLPKVEEQEKVKEALIS 5484
Score = 46.8 bits (106), Expect = 0.001
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG A L+C V + V W K+G ++ + ++ + G L ++ D G YS
Sbjct: 1364 AGAIATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRMEAVGCTRRLVVQQACQADTGEYS 1421
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ +++ L V + V+ + + RE A QA
Sbjct: 1422 CEAG---GQRLSFS-LDVAEPKVVFAKEQPVHREVQA-------------------QAGA 1458
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V WYKDG+++ + + L + G Y A
Sbjct: 1459 STTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA- 1516
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
S +S H + K + A P + G +S V A VTWY+
Sbjct: 1517 -GSQRLSFHLHVAEPKAVFAKEQPA-----SREVQAEAGTSATLSCEV-AQAQTEVTWYK 1569
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + L + DAG Y+C A ++
Sbjct: 1570 DGKKLSSSSKVRMEAVGCTR-RLVVQEAGQADAGEYSCKAGDQ 1611
Score = 46.4 bits (105), Expect = 0.002
Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 22/224 (9%)
Query: 2570 SKAFSEARSVISEKRTLSRNST----RKPVFSTFLTDRTAVEGSRV-KLTCSVISSSDPT 2624
S ++ A+ +S + ST + P L D G+R+ K V P
Sbjct: 5232 SSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPR 5291
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+ W+++G L R L TLE+++ DS +Y+ + N GA +SA L V
Sbjct: 5292 LYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Query: 2685 PSFEASP----------IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI 2734
E +PP + + ++ G+P+P + W +++ +
Sbjct: 5352 GPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 2735 ------PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
P Y A + +D + GTYTC A N+
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLD-VGRQHQGTYTCIASNA 5454
Score = 46.0 bits (104), Expect = 0.002
Identities = 66/285 (23%), Positives = 112/285 (39%), Gaps = 40/285 (14%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K + L V A +D+ EY
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L V E + + + A L C + Q +
Sbjct: 961 SC----EAGGQRLSFHLDVK---EPKVVFAKDQVAHSEVQAEAGASATLSCEV-AQAQTE 1012
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ W+KD K++ S + A G RL + D+G Y+C+A
Sbjct: 1013 VMWYKDGKKLSSS--LKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA-------------- 1056
Query: 2784 FTGRESQVSPNV-VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTR 2842
R +VS + +T K A++ +V + Q G + L E+ T
Sbjct: 1057 ---RGQRVSFRLHITEPKMMFAKEQ---------SVHNEVQAEAGASAMLSCEVAQAQTE 1104
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
V W ++G+ ++ + + V+ L L + ++G Y+C A
Sbjct: 1105 VTWYKDGKKLSSSSK-VGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Score = 46.0 bits (104), Expect = 0.002
Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 36/302 (11%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S +D +W R+G+ + + TL + P DS E + T
Sbjct: 2100 LSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG----VHT 2155
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
SA L V + +P +F+R ++D + ++ LEC + +P + W KD ++ +
Sbjct: 2156 SARLVV------TELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRA- 2207
Query: 2738 GRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
G+ A A G CR L I D G Y C A ++ Q + V GR + V
Sbjct: 2208 GKTMAI-AAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRV 2262
Query: 2797 TAE---KTRIARQSLESRRP--------HFGNVLTDYQVARGGTIGLQVEIRGCPTRVEW 2845
AE + + ++ ESR L D L+ ++ +V W
Sbjct: 2263 LAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRW 2322
Query: 2846 LREGRSVTEVYRNARVFVEQGLY-TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
+ + + + V GLY L +SDV + YTC A G+V +A V +
Sbjct: 2323 FKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEE 2376
Query: 2905 PS 2906
S
Sbjct: 2377 QS 2378
Score = 46.0 bits (104), Expect = 0.002
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 15/168 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L ++ A EG+ L C +S + P V W + L + +Y + + L++
Sbjct: 3280 LRNKEATEGATATLRCE-LSKAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMV 3337
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+AEYSC E TSA+L + P+P F +R + L C +
Sbjct: 3338 DAAEYSCVCGEER----TSASLTI------RPMPAHFIGRLRHQESIEGATATLRCEL-S 3386
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ P + W K + + DG + VC L I D+G Y+C
Sbjct: 3387 KAAP-VEWRKGRESL-RDGDRHSLRQDGAVCELQICGLAVADAGEYSC 3432
Score = 45.6 bits (103), Expect = 0.003
Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 11/188 (5%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISS-SDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+P F T L G +L C + + S V W + GV L KY + L
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATREL 4126
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ D+ EY+C G T+A+L+V P T R + D A+ ++
Sbjct: 4127 LIHQLEAKDTGEYACV----TGGQKTAASLRV-----TEP-EVTIVRGLVDAEVTADEDV 4176
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C + + W + S+ + + L + TPED+GT + N
Sbjct: 4177 EFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGN 4236
Query: 2772 SVWTDQIT 2779
+ Q+T
Sbjct: 4237 HASSAQLT 4244
Score = 45.2 bits (102), Expect = 0.004
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 13/184 (7%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN 2655
F + L+ A EG C V+S SD V W+R+G LL K+ +L + +
Sbjct: 1901 FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISD 1959
Query: 2656 AVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLEC 2715
V D+ + TVE E GA S+SA L+V + P F + + + + LE
Sbjct: 1960 LVLEDAGQ--ITVEAE-GA-SSSAALRVREA------PVLFKKKLEPQTVEERSSVTLEV 2009
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +P P++ W ++ + + G+ + RL + N D G + C+ +
Sbjct: 2010 ELT-RPWPELRWTRNATAL-APGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ 2067
Query: 2776 DQIT 2779
++T
Sbjct: 2068 AKLT 2071
Score = 45.2 bits (102), Expect = 0.004
Identities = 51/205 (24%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 2569 RSKAFSEARSVISEKRTLSRNST-----RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP 2623
R A S+A V+ R L+ ++ R L D+ G V+L C + + P
Sbjct: 2797 REAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2624 TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
V W ++ + KY + L + A D+ EY+C VE A ++A+L V
Sbjct: 2857 -VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE----ASKSTASLHV 2911
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
FT + + + V C+ P +TW K ++ + G++Q
Sbjct: 2912 EEKANC------FTEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQP- 2963
Query: 2744 YLADGV-CRLAIDNPTPEDSGTYTC 2767
+G+ RL I DS TYTC
Sbjct: 2964 -SQEGLTLRLTISALEKADSDTYTC 2987
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 6097 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 6156 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 44.8 bits (101), Expect = 0.006
Identities = 49/192 (25%), Positives = 79/192 (41%), Gaps = 19/192 (9%)
Query: 2579 VISEKRTLSRNSTRKPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
V ++RT S T + + + F+ D + A EG+ L C ++S+ P V W + L
Sbjct: 3521 VCGQERT-SATLTIRALPARFIEDVKNQEAREGATAVLQCE-LNSAAP-VEWRKGSETLR 3577
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT 2695
+ +Y + L++ +D+ EYSC E TSA L V +P
Sbjct: 3578 DGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQER----TSAMLTV------RALPIK 3627
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
FT +R+ VL C + + + W+K + + DG + C L I
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETL-RDGDRHSLRQDGARCELQIR 3684
Query: 2756 NPTPEDSGTYTC 2767
ED+G Y C
Sbjct: 3685 GLVAEDAGEYLC 3696
Score = 44.8 bits (101), Expect = 0.006
Identities = 19/66 (28%), Positives = 35/66 (53%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+VE+ + +T P +PP + + P+F+ + ++ E ++G V +C V G P P
Sbjct: 5097 RVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPS 5156
Query: 3415 VYWLRD 3420
V W +D
Sbjct: 5157 VRWFKD 5162
Score = 43.6 bits (98), Expect = 0.013
Identities = 68/284 (23%), Positives = 108/284 (38%), Gaps = 39/284 (13%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V W K+G ++ + ++ + G L ++ + G YS
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRVEAVGCTRRLVVQQAGQAEAGEYS 1697
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G RL V E + ++ ER E P D
Sbjct: 1698 CEA----GGQQLSFRLQVA------ELEPQIS-ERPCRRE----PLVVKEHED------- 1735
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
+ LT + V+W KDG E+ KR HTL + + D +Y
Sbjct: 1736 -IILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRV- 1793
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG-VTWY 3302
GA + V++ VA +FC LEP+ G ++ E P+ V W
Sbjct: 1794 ---GAEGQDFPVQVEE-----VAAKFCRLLEPVCGELGG---TVTLACELSPACAEVVWR 1842
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+LR +R M + + L + + DAG Y C + ++
Sbjct: 1843 CGNTQLRVGKRFQMVAEGPVR-SLTVLGLRAEDAGEYVCESRDD 1885
Score = 43.2 bits (97), Expect = 0.017
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 32/226 (14%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V+W KDG + + L + DD G+YE +R G ++ +
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAYQLSV--- 791
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+G+ ++ + + + G EA+ V V WY+DG+ L S +
Sbjct: 792 QGLARFLHKDMAGSC--VDAVAGGPAQFECETSEAH--VHVHWYKDGMELGHSGERFLQE 847
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
D + L A VT +D G Y+C VG S ++ V SEP+ V
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV------SEPK---------V 888
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
++KE + RK +A G + + CE V + +V W +D K+
Sbjct: 889 VFAKEQLARRK---LQAEAGASATLSCE-VAQAQTEVTWYKDGKKL 930
Score = 43.2 bits (97), Expect = 0.017
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 14/174 (8%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E + LT ++ + S TVTW ++GV + ++ TL V A DSA YSC
Sbjct: 1732 EHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
V E + +P + + F R + + L C + ++
Sbjct: 1792 RVGAEG---------QDFP-VQVEEVAAKFCRLLEPVCGELGGTVTLACEL-SPACAEVV 1840
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
W + Q+ R+Q +A+G R L + ED+G Y C++ + + Q+T
Sbjct: 1841 WRCGNTQLRVGKRFQ--MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLT 1892
Score = 42.7 bits (96), Expect = 0.022
Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 14/187 (7%)
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR-MTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E L C + +P V W+K+G VE AG+ M G LTI D+G Y C
Sbjct: 2181 EKVTLECELS-RPNVDVRWLKDG--VELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC 2237
Query: 3125 EATNTHGKAS------TYA---RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+A + AS TY R + D + A+ R+ + P LR
Sbjct: 2238 DAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR 2297
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D+ + L CQV +V W+K +E+ + D + L I+ + +D
Sbjct: 2298 DKIAMEKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDE 2356
Query: 3236 GVYEVTA 3242
Y A
Sbjct: 2357 DTYTCDA 2363
Score = 42.3 bits (95), Expect = 0.030
Identities = 67/274 (24%), Positives = 110/274 (40%), Gaps = 43/274 (15%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S VTW ++G L KY + G L V + D+ Y C + G I+
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAY 787
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
+++ F + S D +A EC + + W+KD ++
Sbjct: 788 QLSVQGLARF----LHKDMAGSCVDA--VAGGPAQFECE-TSEAHVHVHWYKDGMELGHS 840
Query: 2738 GRYQAFYLAD-GV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNV 2795
G + F D G RL T +D GTY+C+ V D V+F R S+ P V
Sbjct: 841 G--ERFLQEDVGTRHRLVAATVTRQDEGTYSCR----VGEDS----VDFRLRVSE--PKV 888
Query: 2796 VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEV 2855
V A K ++AR+ L Q G + L E+ T V W ++G+ ++
Sbjct: 889 VFA-KEQLARRKL--------------QAEAGASATLSCEVAQAQTEVTWYKDGKKLSS- 932
Query: 2856 YRNARVFVEQGLYT--LALSDVTETESGLYTCRA 2887
+++V +E T L + + ++G Y+C A
Sbjct: 933 --SSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 42.3 bits (95), Expect = 0.030
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 17/170 (10%)
Query: 2606 VEGSRVKLTC--SVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+EG C S S+SDP + W G + + +++ L V A PSD+ E
Sbjct: 2748 LEGESCSFECVLSHESASDPAM-WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE 2806
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
+V +++ A+L V P + + D + ++ L C + P
Sbjct: 2807 VVFSVRG----LTSKASLIVRER------PAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENS 2772
+ W KD K I +Y + +G + L I + +D+G YTC+ E S
Sbjct: 2857 -VHWLKDRKAIRKSQKYDV--VCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/171 (26%), Positives = 64/171 (37%), Gaps = 13/171 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLITLEVLNAVP 2658
L D EGS C + ++ V W+ + L N+L G L +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
DS T+ E G SA L+V P F+R + D +L L C
Sbjct: 3071 KDSG----TIYFEAGDQRASAALRVTEK------PSVFSRELTDATITEGEDLTLVCETS 3120
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+P + W KD K + R Q + +L I T +DSG Y C+A
Sbjct: 3121 TCDIP-VCWTKDGKTLRGSARCQLSHEGHRA-QLLITGATLQDSGRYKCEA 3169
Score = 42.3 bits (95), Expect = 0.030
Identities = 74/294 (25%), Positives = 110/294 (37%), Gaps = 46/294 (15%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K G E R + + +G C L I +++ D G YSC
Sbjct: 3816 GATAVLQCELS-KAAP-VEWRK-GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC 3872
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R+ + P F L+ + +
Sbjct: 3873 VC----GQERTSATLTV----------------RAPQ------PVFREPLQSLQAEEGST 3906
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C+ + P V W K G ++ + RR Q T E+ +L R
Sbjct: 3907 ATLQCE-LSEPTATVVWSKGGLQLQANGRREPRL--QGCTAELVLQDLQ---------RE 3954
Query: 3245 NSGAVSCHCGLVVDKG-IRAYVAP-EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
++G +C CG + AP F L+ ++ EG + + V W
Sbjct: 3955 DTGEYTCTCGSQATSATLTVTAAPVRFLRELQH-QEVDEGGTAHLCCELSR-AGASVEWR 4012
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ ++L P + M D EL + V DAG YTC + AS S +V
Sbjct: 4013 KGSLQLFPCAKYQMVQD-GAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/174 (25%), Positives = 64/174 (36%), Gaps = 4/174 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
P + VV ++ V+L+W + Y+VE GA G R + P
Sbjct: 4526 PEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEV-KEGATGQWRLCH-ELVPGPECVV 4583
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANL 3070
L GE Y FRV G GE ++ + P ++ AGE +L
Sbjct: 4584 DGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSL 4643
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
V + V+W K G E + GR G L IK +D+G Y C
Sbjct: 4644 ELEVVAE-AGEVIWHK-GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 41.5 bits (93), Expect = 0.052
Identities = 66/284 (23%), Positives = 101/284 (35%), Gaps = 34/284 (11%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+AG A C V V W K+G E+ R + G L + DEG Y
Sbjct: 810 VAGGPAQFECETSEAHVH-VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTY 868
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
SC G+ S RL V + V+ + +R+ AE A
Sbjct: 869 SCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQAE-------------------AG 905
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 906 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+S H + K + A + E + G +S V A V WY
Sbjct: 965 --GGQRLSFHLDV---KEPKVVFAKDQVAHSE--VQAEAGASATLSCEV-AQAQTEVMWY 1016
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+DG +L S + + + + L + DAG Y+C A +
Sbjct: 1017 KDGKKLSSSLK-VHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Score = 41.1 bits (92), Expect = 0.068
Identities = 81/368 (22%), Positives = 141/368 (38%), Gaps = 59/368 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+++ AG + L+C V + V+W K+G ++ + ++ + G L ++
Sbjct: 1451 EVQAQAGASTTLSCEV-AQAQTEVMWYKDGKKLSFSS-KVRMEAVGCTRRLVVQQAGQAV 1508
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G YSCEA G L V + V+ + RE AE
Sbjct: 1509 AGEYSCEA----GSQRLSFHLHVAEPKAVFAKEQPASREVQAEAG--------------- 1549
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
AT L+C+V +V+WYKDG+++ + L + D G Y
Sbjct: 1550 TSAT----LSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A + +S H + K + A P + G +S V A
Sbjct: 1605 SCKAGDQR--LSFHLHVAEPKVVFAKEQPA-----HREVQAEAGASATLSCEV-AQAQTE 1656
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTWY+DG +L S + + ++ G L + +AG Y+C E G S +++
Sbjct: 1657 VTWYKDGKKLSSSSK--VRVEAVGCTRRLVVQQAGQAEAGEYSC----EAGGQQLSFRLQ 1710
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V EP+I + P +EP+ + +E + +I+ + V W
Sbjct: 1711 V----AELEPQI------SERPCRREPLVV--------KEHEDIILTATLATPSAATVTW 1752
Query: 3418 LRDFLKVR 3425
L+D +++R
Sbjct: 1753 LKDGVEIR 1760
Score = 41.1 bits (92), Expect = 0.068
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 8/126 (6%)
Query: 2690 SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK-ITWFKDDKQIPSDGRYQAFYLADG 2748
S IP TR + +VL C R P PK + W+KDD + +++ L
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFR--PAPKAVQWYKDDTPLSPSEKFK-MSLEGQ 2521
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
+ L I P D+G Y C+A ++ + ++T RE V+ + AE T S
Sbjct: 2522 MAELRILRLMPADAGVYRCQAGSAHSSTEVT----VEAREVTVTGPLQDAEATEEGWASF 2577
Query: 2809 ESRRPH 2814
H
Sbjct: 2578 SCELSH 2583
Score = 41.1 bits (92), Expect = 0.068
Identities = 43/181 (23%), Positives = 68/181 (37%), Gaps = 11/181 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D EG C + +S W GV L + G + L L+ V
Sbjct: 4256 LQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTL 4315
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+ A TV G S+ A LKV T R + + L E + EC++
Sbjct: 4316 EDAG---TVSFHVGTCSSEAQLKVTAK-------NTVVRGLENVEALEGGEALFECQLSQ 4365
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQI 2778
+ TW DD+ + + + + +G+ L + N P+DS T A + V + +
Sbjct: 4366 PEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFL 4425
Query: 2779 T 2779
T
Sbjct: 4426 T 4426
Score = 40.3 bits (90), Expect = 0.12
Identities = 92/365 (25%), Positives = 137/365 (37%), Gaps = 78/365 (21%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K GHE + R + + +G C L I+ + +D G Y C
Sbjct: 3640 GATAVLRCELS-KMAP-VEWWK-GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC 3696
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
GK T A L V R + P +F LR+
Sbjct: 3697 MC----GKERTSAMLTV---RAM-------------------PSKFIEGLRNEEATEGDT 3730
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I + D G Y
Sbjct: 3731 ATLWCELSKAAP--VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEY------ 3782
Query: 3245 NSGAVSCHCG---LVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
SC CG +RA A F +E + + E + V W
Sbjct: 3783 -----SCVCGQERTSATLTVRALPA-RF---IEDVKNQEAREGATAVLQCELSKAAPVEW 3833
Query: 3302 YRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ LR R +L +DG + EL + ++ D G Y+C G+ TS + V
Sbjct: 3834 RKGSETLRGGDR--YSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV-- 3885
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R P P +EP+ +S +A EG T ++CE + +P V W +
Sbjct: 3886 -------RAPQ-------PVFREPL-----QSLQAEEGSTATLQCE-LSEPTATVVWSKG 3925
Query: 3421 FLKVR 3425
L+++
Sbjct: 3926 GLQLQ 3930
Score = 39.5 bits (88), Expect = 0.21
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 3/135 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + V+ G L +I G PT +V W ++ + V R R+ + LY
Sbjct: 7 SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGAR-FRLAQDGDLY 65
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
L + D+ +SG Y CRA +A G + V + + + RP I + G
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREG 124
Query: 2929 EDINISFRTQGEPKP 2943
+ R G P+P
Sbjct: 125 SEATFRCRVGGSPRP 139
Score = 39.1 bits (87), Expect = 0.28
Identities = 68/307 (22%), Positives = 115/307 (37%), Gaps = 43/307 (14%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
KPV F L D +A E + L C V S + V W ++GV L KY G L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
V + P D+ Y+C V G+ T A ++V+ + T+ ++ L
Sbjct: 2704 VVHDVSPEDAGLYTCHV----GSEETRARVRVH------DLHVGITKRLKTMEVLEGESC 2753
Query: 2712 VLECRIRGQPL-PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
EC + + W K + S R+QA L + P D+G
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYI-LVVREAAPSDAGE------ 2806
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
V F+ R +++ E+ + LE D VA G +
Sbjct: 2807 -----------VVFSVRGLTSKASLIVRERPAAIIKPLE-----------DQWVAPGEDV 2844
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ E+ T V WL++ +++ + + V E + L + + ++G YTC ++
Sbjct: 2845 ELRCELSRAGTPVHWLKDRKAIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Query: 2891 HGNVDMN 2897
++
Sbjct: 2904 KSTASLH 2910
Score = 38.7 bits (86), Expect = 0.36
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P V W +DGV+L PS + L G L + V+ DAG+YTC +E RA
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDF-LHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRA 2727
Score = 37.9 bits (84), Expect = 0.64
Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
V WY+D L PS + M+L +GQ+ EL + + DAGVY C A + +ST VE
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSL--EGQMAELRILRLMPADAGVYRCQAGS--AHSSTEVTVE 2554
Score = 37.5 bits (83), Expect = 0.84
Identities = 13/41 (31%), Positives = 23/41 (56%)
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+S P F+ +P++ G + C++VG+P P V W +D
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKD 46
Score = 37.5 bits (83), Expect = 0.84
Identities = 46/178 (25%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+ +R + VQA +T V + W+ DG+ + + D HTL I
Sbjct: 611 PKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTI 670
Query: 3228 --APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
P +L G + A N S + G+ A P E L +LHE +L
Sbjct: 671 REVPASL-HGAQLKFVA--NGIESSIRMEVRAAPGLTAN-KPPAAAAREVLARLHEEAQL 726
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTA 3343
+A VTW +DG L P + + G+ L + V DAG+Y C +
Sbjct: 727 LAELSDQA---AAVTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECVS 780
Score = 36.7 bits (81), Expect = 1.5
Identities = 40/168 (23%), Positives = 66/168 (39%), Gaps = 14/168 (8%)
Query: 3185 VRLTCQVIGSPP-PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V L C++ SP +V W ++ KR + +L + +D G Y +R
Sbjct: 1826 VTLACEL--SPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESR 1883
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
++ S + V + ++ F GL + EG E VV V V W+R
Sbjct: 1884 DDH--TSAQLTVSVPRVVK------FMSGLSTVVA-EEGGEATFQCVVSP-SDVAVVWFR 1933
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
DG L+PS + ++ L ++ + DAG T A A+
Sbjct: 1934 DGALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSAA 1980
Score = 36.3 bits (80), Expect = 1.9
Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GE L C +P V W K+G + A R G L I + D GR
Sbjct: 3107 ITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA-RCQLSHEGHRAQLLITGATLQDSGR 3164
Query: 3122 YSCEA 3126
Y CEA
Sbjct: 3165 YKCEA 3169
Score = 35.9 bits (79), Expect = 2.6
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLL--DNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
EGS C V S P V+W ++G L + + R + + L + A P D Y
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 2665 SCTVENENGAISTSANLKV 2683
EN GA S +A L V
Sbjct: 183 EVRAENPLGAASAAAALVV 201
Score = 35.9 bits (79), Expect = 2.6
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 3050 PEFVDILPGQLKILA--GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
P V + G ++A G A C V V VVW ++G ++ SQ +G
Sbjct: 1896 PRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-AVVWFRDGALLQPSEKFAISQ-SGASH 1953
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
LTI D+ ++D G+ + EA A+ R A V
Sbjct: 1954 SLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Score = 35.5 bits (78), Expect = 3.4
Identities = 43/195 (22%), Positives = 73/195 (37%), Gaps = 19/195 (9%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
P L D+ V V L C++ + P V W KD + + ++ + + L
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLV 2884
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-EGDEL 3285
I +L D G Y + S H V + C E L L E
Sbjct: 2885 IRGASLKDAGEYTCEVEASKSTASLH------------VEEKANCFTEELTNLQVEEKGT 2932
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ +P+ VTW + + LR S + + L ++A+ D+ YTC
Sbjct: 2933 AVFTCKTEHPAATVTWRKGLLELRASGKH-QPSQEGLTLRLTISALEKADSDTYTC---- 2987
Query: 3346 EVGRASTSGKVEVIG 3360
++G+A + ++ V G
Sbjct: 2988 DIGQAQSRAQLLVQG 3002
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 6008 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 6056
Score = 34.3 bits (75), Expect = 7.9
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 2804 ARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFV 2863
AR + + F L D GT+ LQ E+ V W ++G + + +
Sbjct: 2638 ARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWS 2889
G L + DV+ ++GLYTC S
Sbjct: 2698 -AGTRGLVVHDVSPEDAGLYTCHVGS 2722
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 103 bits (246), Expect = 1e-20
Identities = 81/267 (30%), Positives = 109/267 (40%), Gaps = 16/267 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+F R + V L+CQ++G+P P+VSW KD + V R QD + L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTI 69
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD-KGIRAYVAPEFCCGLEPL-YKLHEGDEL 3285
L D G Y ARN G GL VD + A AP F L P ++ EG E
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFL--LRPTSIRVREGSEA 127
Query: 3286 RISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
V P V+W +DG RL P + + L + A RD G Y A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 3345 NEVGRASTSGK--VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR----KPRSSEAR-- 3396
N +G AS + V+ D S P + + +E M P S+ R
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTC 247
Query: 3397 ---EGDTVIIECEVVGDPKPDVYWLRD 3420
EG + C V G+PKP+ W +D
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKD 274
Score = 102 bits (244), Expect = 3e-20
Identities = 142/607 (23%), Positives = 224/607 (36%), Gaps = 61/607 (10%)
Query: 2802 RIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNAR 2860
++ ++ + P F + D + G + L+ + R WL++G +T+ +
Sbjct: 4887 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 4946
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPE 2920
+ G +L ++ + ++G YTC+ + G V +A V+V E
Sbjct: 4947 DQLGDGTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSAC--------------VVVSGSE 4992
Query: 2921 KDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVL 2980
+ S G +++ +FR + + P E V ++S ++P+ A
Sbjct: 4993 SEAESSSGGELDDAFRRAARRLHRLFRTKSPAE---VSDEELFLSADEGPAEPEEPADWQ 5049
Query: 2981 AYKVESWLIGAEGGARW-VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
Y+ + I A +T A L G E R S +T +
Sbjct: 5050 TYREDEHFICIRFEALTEARQAVTRFQEMFA-TLGIGVEIKLVEQGPRRVEMCISKETPA 5108
Query: 3040 SIGVG------LAGDR-PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
+ L D P F+ L Q ++ G + C V G+P+P V W K+G +E
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQ-EVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE 5167
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--A 3150
E+ M ++ L I + D G Y C A N+ G +ST A L V T ++ A
Sbjct: 5168 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAA 5227
Query: 3151 DAKLKRE--------RSAEVEGDYP-------PQFTMRLRDRRV-QATYPVRLTCQVIGS 3194
DA S E EG PQ LRD +V T + +V G
Sbjct: 5228 DATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY 5287
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
P P++ W+KDG+ + + HTLEI +D G Y N GA
Sbjct: 5288 PAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSAR 5347
Query: 3255 LVV----------DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
L+V + + P K+ +G + S VE P V W R+
Sbjct: 5348 LLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLRE 5407
Query: 3305 ----GVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
GV + P Q L L V + G YTC ASN G+A S + V
Sbjct: 5408 EAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS 5467
Query: 3360 GTDQTSE 3366
G + E
Sbjct: 5468 GLPKVEE 5474
Score = 85.4 bits (202), Expect = 3e-15
Identities = 91/309 (29%), Positives = 127/309 (41%), Gaps = 23/309 (7%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNG 3104
A P F+ + P +++ G A C V G P P V W K+G + E G R+ + G
Sbjct: 106 AEQAPHFL-LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELG 164
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEAD---------AKLK 3155
L I+ D G Y A N G AS A L V +D + A L+
Sbjct: 165 EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224
Query: 3156 RERSA-EVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR 3214
R R A EG + R V RL+C V G P P+ W KDG+ V +R
Sbjct: 225 RRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRH 284
Query: 3215 NKYQDEQFH-TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
Y+D Q + L+I D G+Y TA N G LVV +R P F L
Sbjct: 285 VVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVV---VREPAVP-FKKRL 339
Query: 3274 EPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVT 3332
+ L ++ E + V PS W+++ RL S A ++ +G + L + V+
Sbjct: 340 QDL-EVREKESATFLCEV-PQPSTEAAWFKEETRLWAS--AKYGIEEEGTERRLTVRNVS 395
Query: 3333 TRDAGVYTC 3341
D VY C
Sbjct: 396 ADDDAVYIC 404
Score = 84.2 bits (199), Expect = 7e-15
Identities = 67/204 (32%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + G+ A L+C + G P P V W K+ V A +Q +G LTI D+ +
Sbjct: 16 PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQ-DGDLYRLTILDLAL 74
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G+Y C A N G+A L V +A+A + P F +R
Sbjct: 75 GDSGQYVCRARNAIGEAFAAVGLQV-------DAEAAC---------AEQAPHFLLRPTS 118
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQD-EQFHTLEIAPTNLDD 3234
RV+ C+V GSP P VSW KDG + D R + ++ + L I D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD 3258
GG YEV A N GA S LVVD
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVD 202
Score = 84.2 bits (199), Expect = 7e-15
Identities = 75/285 (26%), Positives = 120/285 (42%), Gaps = 27/285 (9%)
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
PS S P F +++ + +C + GQP+P + WFKD K + D Y
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENS--VWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
G +L I P D G Y C AENS V + + V+ T + + + +
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 2803 IARQSLESRR-------------PHFGNVLTDYQVARGGTIG-LQVEIRGCPT-RVEWLR 2847
A+ L SR P L D QVA G + Q++++G P R+ W +
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 2848 EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD 2907
+G+ +T + R+ ++ L+TL + VT +SG Y +A G +A + V P +
Sbjct: 5297 DGQPLT-ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 2908 LDGKPAVIVGR---PEKDI------LISVGEDINISFRTQGEPKP 2943
+ KPA V P + + + G I S + +G P P
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVP 5400
Score = 80.2 bits (189), Expect = 1e-13
Identities = 70/310 (22%), Positives = 118/310 (38%), Gaps = 12/310 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L+C ++ + P V+W ++ + ++R L L +L+ DS +Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N G + L+V + P F +E CR+ G P P ++W
Sbjct: 84 ARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSW 143
Query: 2728 FKDDKQI--PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH--FVN 2783
KD +++ P R + L + L I P D GTY +AEN + V+
Sbjct: 144 SKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVD 202
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV------LTDYQVARGGTIGLQVEIR 2837
++ P TA ++ E+ R V G L +
Sbjct: 203 SDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVT 262
Query: 2838 GCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDM 2896
G P W ++G+ VTE R+ Q + L + +++ GLYTC A + G
Sbjct: 263 GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYS 322
Query: 2897 NAAITVVQPS 2906
+ + V +P+
Sbjct: 323 SVLVVVREPA 332
Score = 78.6 bits (185), Expect = 4e-13
Identities = 53/194 (27%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F EG++
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRF-VNKVLASPFVEGEDA 6125
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 6186 NRLGSARASAELRI 6199
Score = 74.5 bits (175), Expect = 6e-12
Identities = 50/182 (27%), Positives = 77/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F + + + +
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVLASPFVEGED 6124
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 2770 EN 2771
N
Sbjct: 6185 VN 6186
Score = 68.5 bits (160), Expect = 4e-10
Identities = 107/437 (24%), Positives = 165/437 (37%), Gaps = 49/437 (11%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ L C+I G P P+++W KD + + + R++ D + RL I + DSG Y C+A
Sbjct: 26 DATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGD-LYRLTILDLALGDSGQYVCRA 84
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N++ F QV AE+ PHF T +V G
Sbjct: 85 RNAIGEA-------FAAVGLQVDAEAACAEQA-----------PHFLLRPTSIRVREGSE 126
Query: 2830 IGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQ--GLYTLALSDVTETESGLYTCR 2886
+ + G P V W ++GR + E RV VE+ L + + G Y R
Sbjct: 127 ATFRCRVGGSPRPAVSWSKDGRRLGEP-DGPRVRVEELGEASALRIRAARPRDGGTYEVR 185
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI--LISVGEDINISFRTQGEPKPK 2944
A + G AA+ V D A RP L++ + + R +G P
Sbjct: 186 AENPLGAASAAAALVV------DSDAADTASRPGTSTAALLAHLQRRREAMRAEGAP--- 236
Query: 2945 AVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP 3004
A P C V G + + +P+ P +K + L+ EG V
Sbjct: 237 ASPPSTGTRTCTVTEGKHARLSCYVTGEPK---PETVWKKDGQLV-TEGRRHVVYEDAQE 292
Query: 3005 LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
KQ + + T N G QT SS+ V + F L L++
Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVG-----QTYSSVLVVVREPAVPFKKRLQ-DLEVRE 346
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E+A C V +P W K + A + + G + LT+++++ DD+ Y C
Sbjct: 347 KESATFLCEVP-QPSTEAAWFKEETRLWASA-KYGIEEEGTERRLTVRNVSADDDAVYIC 404
Query: 3125 EATNTHGKASTYARLAV 3141
E T + T A LAV
Sbjct: 405 E---TPEGSRTVAELAV 418
Score = 62.5 bits (145), Expect = 3e-08
Identities = 45/186 (24%), Positives = 73/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++
Sbjct: 6088 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVLASPFVEGED 6124
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 6125 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 6184
Query: 3243 RNNSGA 3248
N G+
Sbjct: 6185 VNRLGS 6190
Score = 60.1 bits (139), Expect = 1e-07
Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
V+ YP+ + W++DG L S MT D+ L + +VT D+G Y SN +G A
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+S ++ V G D+ E + V VP P + + + ++G ++ +V G
Sbjct: 5343 YSSARLLVRGPDEPEE-KPASDVHEQLVP----PRMLERFTPKKVKKGSSITFSVKVEGR 5397
Query: 3411 PKPDVYWLRD 3420
P P V+WLR+
Sbjct: 5398 PVPTVHWLRE 5407
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 6013 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 6072 LILDSLTGVDSGQYMCFAASA 6092
Score = 56.8 bits (131), Expect = 1e-06
Identities = 62/283 (21%), Positives = 114/283 (40%), Gaps = 36/283 (12%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K ++ L + A +D+ EY
Sbjct: 1086 AEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEY 1144
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L + + ++ A +L C + QP +
Sbjct: 1145 SC----EAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAE---AGTTAMLSCEV-AQPQTE 1196
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + + RL + D+G Y+C+A + Q+ H
Sbjct: 1197 VTWYKDGKKLSSSSKVR-MEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQL-H---- 1250
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+T K A++ L V + + G + L E+ T V
Sbjct: 1251 -----------ITEPKAVFAKEQL---------VHNEVRTEAGASATLSCEVAQAQTEVT 1290
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ + L + + ++G YTC A
Sbjct: 1291 WYKDGKKLSSSSK-VRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 55.6 bits (128), Expect = 3e-06
Identities = 70/283 (24%), Positives = 111/283 (39%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG A L+C V + V+W K+G ++ ++ + G L ++ D G YS
Sbjct: 996 AGANATLSCEV-AQAQAEVMWYKDGKKLSSSL-KVHVEAKGCRRRLVVQQAGKTDAGDYS 1053
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ ++ RL + + ++ + + E AE A
Sbjct: 1054 CEA---RGQRVSF-RLHITEPKMMFAKEQSVHNEVQAE-------------------AGA 1090
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 1091 SAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAG 1149
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
VS H + KG+ A E E + G +S V A P VTWY+
Sbjct: 1150 GQR--VSFHLHITEPKGV---FAKEQSVHNE--VQAEAGTTAMLSCEV-AQPQTEVTWYK 1201
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + + L + V DAG Y+C A +
Sbjct: 1202 DGKKLSSSSKVRMEV-KGCTRRLVVQQVGKADAGEYSCEAGGQ 1243
Score = 54.0 bits (124), Expect = 9e-06
Identities = 65/301 (21%), Positives = 117/301 (38%), Gaps = 40/301 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + VTWY++G L + K R ++ L V +D+ EY
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S L + +R A L C + Q +
Sbjct: 1237 SC----EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTE---AGASATLSCEV-AQAQTE 1288
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
+TW+KD K++ S + + A + +L + D+G YTC+A +++ ++
Sbjct: 1289 VTWYKDGKKLSSSSKVR-IEAAGCMRQLVVQQAGQADAGEYTCEAGG----QRLSFHLD- 1342
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
V+ K A++ L R+ Q G L E+ T V
Sbjct: 1343 -----------VSEPKAVFAKEQLAHRK---------VQAEAGAIATLSCEVAQAQTEVT 1382
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
W ++G+ ++ + R+ L + + ++G Y+C A G ++ ++ V +
Sbjct: 1383 WYKDGKKLSSSSK-VRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAE 1437
Query: 2905 P 2905
P
Sbjct: 1438 P 1438
Score = 54.0 bits (124), Expect = 9e-06
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC ++ S +L V E + + R+ A L C + Q +
Sbjct: 1605 SCKAGDQR----LSFHLHV---AEPKVVFAKEQPAHREVQAEAGASATLSCEV-AQAQTE 1656
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+TW+KD K++ S + + RL + D+G Y+C+A
Sbjct: 1657 VTWYKDGKKLSSSSKVRV-EAVGCTRRLVVQQAGQADAGEYSCEA 1700
Score = 54.0 bits (124), Expect = 9e-06
Identities = 47/178 (26%), Positives = 74/178 (41%), Gaps = 14/178 (7%)
Query: 2591 TRKP-VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
T KP VFS LTD T EG + L C S+ D + W ++G L + +
Sbjct: 3092 TEKPSVFSRELTDATITEGEDLTLVCET-STCDIPMCWTKDGKTLRGSARCQLSHEGHRA 3150
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
L + A DS Y C E G +S+ ++V+ A P+ F +++D L
Sbjct: 3151 QLLITGATLQDSGRYKC----EAGGACSSSIVRVH----ARPV--RFQEALKDLEVLEGG 3200
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + P + W + + +Y + + L + N P+DSG Y+C
Sbjct: 3201 AATLRCVLSSVAAP-VKWCYGNNVLRPGDKY-SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGL 2648
S PVF T L ++ +G V C V P+V W+++G LL+ Y + G
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 2649 ITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
L + VP+D Y C EN G ST A L+V
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 53.2 bits (122), Expect = 2e-05
Identities = 65/283 (22%), Positives = 110/283 (38%), Gaps = 34/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V W K+G ++ + ++ + G L +++ D G YS
Sbjct: 1548 AGTSATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRMEAVGCTRRLVVQEAGQADAGEYS 1605
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C+A G L V + V+ + RE AE AT
Sbjct: 1606 CKA----GDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGAS---------------AT- 1645
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 1646 ---LSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAG 1701
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+ H + + E C EPL + E +++ ++A + + VTW +
Sbjct: 1702 GQRLSFRLHVAELEPQ------ISERPCRREPLV-VKEHEDIILTATLATPSAATVTWLK 1754
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DGV +R S+R T + L + D+ +Y+C E
Sbjct: 1755 DGVEIRRSKRH-ETASQGDTHTLTVHGAQVLDSAIYSCRVGAE 1796
Score = 52.8 bits (121), Expect = 2e-05
Identities = 64/284 (22%), Positives = 114/284 (40%), Gaps = 38/284 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K R + V L V A +D+ EY
Sbjct: 1362 AEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEY 1420
Query: 2665 SCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
SC E G S +L V P + P R+ A L C + Q
Sbjct: 1421 SC----EAGGQRLSFSLDVAEPKVVFAKEQPVH----REVQAQAGASTTLSCEV-AQAQT 1471
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++ W+KD K++ + + RL + D+G Y+C+A + +++ ++
Sbjct: 1472 EVMWYKDGKKLSFSSKVR-MEAVGCTRRLVVQQAGQADAGEYSCEA----GSQRLSFHLH 1526
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V K A++ SR + Q G + L E+ T V
Sbjct: 1527 ------------VAEPKAVFAKEQPASR---------EVQAEAGTSATLSCEVAQAQTEV 1565
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
W ++G+ ++ + R+ L + + + ++G Y+C+A
Sbjct: 1566 TWYKDGKKLSSSSK-VRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Score = 52.0 bits (119), Expect = 4e-05
Identities = 75/289 (25%), Positives = 115/289 (39%), Gaps = 47/289 (16%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+TA L C + K P V W K GHE + R + + +G C L I+ + + D G YSC
Sbjct: 3728 GDTATLWCELS-KAAP-VEWRK-GHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSC 3784
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R + P +F ++++ +
Sbjct: 3785 VC----GQERTSATLTV---RAL-------------------PARFIEDVKNQEAREGAT 3818
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I ++ D G Y
Sbjct: 3819 AVLQCELSKAAP--VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEY------ 3870
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL--HEGDELRISAVVEAYPSVGVTWY 3302
SC CG AP+ EPL L EG + + + P+ V W
Sbjct: 3871 -----SCVCGQERTSATLTVRAPQ-PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWS 3923
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
+ G++L+ + R L + EL L + D G YTCT ++ A+
Sbjct: 3924 KGGLQLQANGRREPRL-QGCTAELVLQDLQREDTGEYTCTCGSQATSAT 3971
Score = 51.2 bits (117), Expect = 6e-05
Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 13/168 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D A E +C +S D V W NG+ L N + TL + + +
Sbjct: 2564 LQDAEATEEGWASFSCE-LSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRA 2622
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ V + +STSA L+V P F +++ D L L+C +
Sbjct: 2623 DAG----IVRASSLKVSTSARLEVRVK------PVVFLKALDDLSAEERGTLALQCEV-S 2671
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
P + W KD Q+ +Y + A G L + + +PED+G YTC
Sbjct: 2672 DPEAHVVWRKDGVQLGPSDKYDFLHTA-GTRGLVVHDVSPEDAGLYTC 2718
Score = 51.2 bits (117), Expect = 6e-05
Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 17/196 (8%)
Query: 2575 EARSVISEKRTLSRNSTR--KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV 2632
E V ++RT + + R +PVF L A EGS L C +S TV W + G+
Sbjct: 3869 EYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGL 3927
Query: 2633 LLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPI 2692
L + +L L + + D+ EY+CT G+ +TSA L V A+P+
Sbjct: 3928 QLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTV----TAAPV 3979
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCR 2751
F R ++ + E C + + W K Q+ +YQ + DG
Sbjct: 3980 --RFLRELQHQ-EVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQ--MVQDGAAAE 4034
Query: 2752 LAIDNPTPEDSGTYTC 2767
L + ED+G YTC
Sbjct: 4035 LLVRGVEQEDAGDYTC 4050
Score = 50.4 bits (115), Expect = 1e-04
Identities = 68/283 (24%), Positives = 109/283 (38%), Gaps = 35/283 (12%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG A L+C V + V W K+G ++ + ++ + G L ++ D G YS
Sbjct: 1364 AGAIATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRMEAVGCTRRLVVQQACQADTGEYS 1421
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ +++ L V + V+ + + RE A QA
Sbjct: 1422 CEAG---GQRLSFS-LDVAEPKVVFAKEQPVHREVQA-------------------QAGA 1458
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V WYKDG+++ + + L + D G Y A
Sbjct: 1459 STTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQADAGEYSCEA- 1516
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
S +S H + K + A P + G +S V A VTWY+
Sbjct: 1517 -GSQRLSFHLHVAEPKAVFAKEQPA-----SREVQAEAGTSATLSCEV-AQAQTEVTWYK 1569
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
DG +L S + M + L + DAG Y+C A ++
Sbjct: 1570 DGKKLSSSSKVRMEAVGCTR-RLVVQEAGQADAGEYSCKAGDQ 1611
Score = 50.0 bits (114), Expect = 1e-04
Identities = 40/140 (28%), Positives = 57/140 (40%), Gaps = 22/140 (15%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG R+S V P W +DG + RR ++ D L + D G+YT
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDT 3400
CTASN VG+ +S V VV P VP+ K + + E RE ++
Sbjct: 311 CTASNLVGQTYSSVLV---------------VVREPAVPFKK------RLQDLEVREKES 349
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
CE V P + W ++
Sbjct: 350 ATFLCE-VPQPSTEAAWFKE 368
Score = 50.0 bits (114), Expect = 1e-04
Identities = 84/361 (23%), Positives = 138/361 (38%), Gaps = 58/361 (16%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG TA L+C V +P V W K+G ++ + ++ + G L ++ + D G YS
Sbjct: 1180 AGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSS-KVRMEVKGCTRRLVVQQVGKADAGEYS 1237
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G +L + + V+ + + E R +A
Sbjct: 1238 CEA----GGQRVSFQLHITEPKAVFAKEQLVHNEV-------------------RTEAGA 1274
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L+C+V +V+WYKDG+++ + L + D G Y T
Sbjct: 1275 SATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY--TCE 1331
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+S H + K + A E + + G +S V A VTWY+
Sbjct: 1332 AGGQRLSFHLDVSEPKAV---FAKEQLAHRK--VQAEAGAIATLSCEV-AQAQTEVTWYK 1385
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
DG +L S + M + L + D G Y+C A + R S S V
Sbjct: 1386 DGKKLSSSSKVRMEAVGCTR-RLVVQQACQADTGEYSCEAGGQ--RLSFSLDV------- 1435
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLK 3423
+EP+ VV + + P +E +A+ G + + CE V + +V W +D K
Sbjct: 1436 -AEPK---VVFAKEQPVHRE---------VQAQAGASTTLSCE-VAQAQTEVMWYKDGKK 1481
Query: 3424 V 3424
+
Sbjct: 1482 L 1482
Score = 50.0 bits (114), Expect = 1e-04
Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRL 2752
P F+ + DT + L LEC + + + W KD ++ +DGR+ L DG C L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL-TDGRHHHIDQLGDGTCSL 4956
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITH--FVNFTGRESQ 2790
I D+G YTC+ N Q+TH V +G ES+
Sbjct: 4957 LIAGLDRADAGCYTCQVSNKF--GQVTHSACVVVSGSESE 4994
Score = 50.0 bits (114), Expect = 1e-04
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLE 2652
P+FS D A G ++L C V S +D W ++GV L D + + +L DG +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSA 2679
+ +D+ Y+C V N+ G ++ SA
Sbjct: 4958 IAGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 49.6 bits (113), Expect = 2e-04
Identities = 51/177 (28%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLIT 2650
+PV F L D +EG L C V+SS V W Y N VL KY + ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGD-KYSLRQEGAMLE 3240
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L V N P DS YSC+ G +TSA L V + +P F +R+
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTV------TALPAQFIGKLRNKEATEGAT 3290
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
L C + + P + W K + + RY +C L I D+ Y+C
Sbjct: 3291 ATLRCEL-SKTAP-VEWRKGSETLRDGDRY-CLRQDGAMCELQIRGLAMVDAAEYSC 3344
Score = 49.6 bits (113), Expect = 2e-04
Identities = 81/357 (22%), Positives = 133/357 (37%), Gaps = 47/357 (13%)
Query: 3001 GITPLNSFDAFNLKQ-GEEYHFRVTPRNRYGWGESS----QTSSSIGVGLAGDRPEFVDI 3055
G L D ++L+Q G ++ + GE S Q +S + + +P F +
Sbjct: 3836 GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREP 3895
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
L L+ G TA L C + +P VVW K G +++ GR + G L ++D+
Sbjct: 3896 LQS-LQAEEGSTATLQCELS-EPTATVVWSKGGLQLQAN-GRREPRLQGCTAELVLQDLQ 3952
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+D G Y+C T G +T A L V P +F L+
Sbjct: 3953 REDTGEYTC----TCGSQATSATLTVTA----------------------APVRFLRELQ 3986
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ V L C+ + V W K ++ + QD L + +D
Sbjct: 3987 HQEVDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA-VVEAY 3294
G Y ++G H + +R P+F L+ L + GD R+ + +A
Sbjct: 4046 GDYTC----DTG----HTQSMASLSVRV-PRPKFKTRLQSL-EQETGDIARLCCQLSDAE 4095
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
V W ++GV L + M + EL + + +D G Y C + AS
Sbjct: 4096 SGAVVQWLKEGVELHAGPKYEMR-SQGATRELLIHQLEAKDTGEYACVTGGQKTAAS 4151
Score = 49.6 bits (113), Expect = 2e-04
Identities = 44/162 (27%), Positives = 67/162 (41%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K ++ P + GE
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VLASPFVE-----GE 6123
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 6124 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 6162
Score = 49.2 bits (112), Expect = 3e-04
Identities = 38/166 (22%), Positives = 67/166 (40%), Gaps = 9/166 (5%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLL-DNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T EG +L+C V P W ++G L+ + + + L++L SD
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+CT N G +S + V P P F + ++D + C + QP
Sbjct: 308 LYTCTASNLVGQTYSSVLVVV-----REPAVP-FKKRLQDLEVREKESATFLCEV-PQPS 360
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ WFK++ ++ + +Y RL + N + +D Y C+
Sbjct: 361 TEAAWFKEETRLWASAKY-GIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 6120 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 6179
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 6180 YECELVNRLGSARASAELRI 6199
Score = 48.0 bits (109), Expect = 6e-04
Identities = 70/288 (24%), Positives = 109/288 (37%), Gaps = 35/288 (12%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L+ AG +A L+C V + V W K+G ++ + ++ + G L ++ D
Sbjct: 899 KLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVCMEATGCTRRLVVQQAGQAD 956
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G YSCEA G L V + V+ D E AE +
Sbjct: 957 AGEYSCEA----GGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGAN------------- 999
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
AT L+C+V +V WYKDG+++ + + L + D G Y
Sbjct: 1000 --AT----LSCEV-AQAQAEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
AR + H + + + A E E + G +S V A
Sbjct: 1053 SCEARGQRVSFRLH---ITEP--KMMFAKEQSVHNE--VQAEAGASAMLSCEV-AQAQTE 1104
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
VTWY+DG +L S + M + + L L DAG Y+C A +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEV-KGCTRRLVLPQAGKADAGEYSCEAGGQ 1151
Score = 47.6 bits (108), Expect = 8e-04
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Query: 2664 YSCTVENENGAISTSA-NLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y + + G I A N + +P T R +RD + ++ VLEC++ +
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQV-SRAS 2317
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKA 2769
++ WFK +++ +Y+ ++DG+ R L I + ED TYTC A
Sbjct: 2318 AQVRWFKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Score = 47.6 bits (108), Expect = 8e-04
Identities = 55/221 (24%), Positives = 90/221 (40%), Gaps = 25/221 (11%)
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAEN 2771
+ +++G P P++ WFKD + + + + + D + L I + T EDSG Y N
Sbjct: 5281 QLKVKGYPAPRLYWFKDGQPLTASAHIR---MTDKKILHTLEIISVTREDSGQYAAYISN 5337
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
++ + + G + + + + LE P +V +G +I
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPK--------KVKKGSSIT 5389
Query: 2832 LQVEIRGCPT-RVEWLREG--RSVTEVYRNA---RVFVEQGLYTLALSDVTETESGLYTC 2885
V++ G P V WLRE R V + + V ++L L DV G YTC
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 5449
Query: 2886 RAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
A +A G +A++ V G P V K+ LIS
Sbjct: 5450 IASNAAGQALCSASLHV------SGLPKVEEQEKVKEALIS 5484
Score = 46.4 bits (105), Expect = 0.002
Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 22/224 (9%)
Query: 2570 SKAFSEARSVISEKRTLSRNST----RKPVFSTFLTDRTAVEGSRV-KLTCSVISSSDPT 2624
S ++ A+ +S + ST + P L D G+R+ K V P
Sbjct: 5232 SSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPR 5291
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+ W+++G L R L TLE+++ DS +Y+ + N GA +SA L V
Sbjct: 5292 LYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Query: 2685 PSFEASP----------IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI 2734
E +PP + + ++ G+P+P + W +++ +
Sbjct: 5352 GPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 2735 ------PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
P Y A + +D + GTYTC A N+
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLD-VGRQHQGTYTCIASNA 5454
Score = 46.0 bits (104), Expect = 0.002
Identities = 66/285 (23%), Positives = 112/285 (39%), Gaps = 40/285 (14%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G+ L+C V + + VTWY++G L + K + L V A +D+ EY
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
SC E G S +L V E + + + A L C + Q +
Sbjct: 961 SC----EAGGQRLSFHLDVK---EPKVVFAKDQVAHSEVQAEAGANATLSCEV-AQAQAE 1012
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ W+KD K++ S + A G RL + D+G Y+C+A
Sbjct: 1013 VMWYKDGKKLSSS--LKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA-------------- 1056
Query: 2784 FTGRESQVSPNV-VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTR 2842
R +VS + +T K A++ +V + Q G + L E+ T
Sbjct: 1057 ---RGQRVSFRLHITEPKMMFAKEQ---------SVHNEVQAEAGASAMLSCEVAQAQTE 1104
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
V W ++G+ ++ + + V+ L L + ++G Y+C A
Sbjct: 1105 VTWYKDGKKLSSSSK-VGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Score = 46.0 bits (104), Expect = 0.002
Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 36/302 (11%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S +D +W R+G+ + + TL + P DS E + T
Sbjct: 2100 LSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG----VHT 2155
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
SA L V + +P +F+R ++D + ++ LEC + +P + W KD ++ +
Sbjct: 2156 SARLVV------TELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRA- 2207
Query: 2738 GRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVV 2796
G+ A A G CR L I D G Y C A ++ Q + V GR + V
Sbjct: 2208 GKTMAI-AAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRV 2262
Query: 2797 TAE---KTRIARQSLESRRP--------HFGNVLTDYQVARGGTIGLQVEIRGCPTRVEW 2845
AE + + ++ ESR L D L+ ++ +V W
Sbjct: 2263 LAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRW 2322
Query: 2846 LREGRSVTEVYRNARVFVEQGLY-TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
+ + + + V GLY L +SDV + YTC A G+V +A V +
Sbjct: 2323 FKGSQELQPGPKYE--LVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEE 2376
Query: 2905 PS 2906
S
Sbjct: 2377 QS 2378
Score = 46.0 bits (104), Expect = 0.002
Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 15/168 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L ++ A EG+ L C +S + P V W + L + +Y + + L++
Sbjct: 3280 LRNKEATEGATATLRCE-LSKTAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMV 3337
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+AEYSC E TSA+L + P+P F +R + L C +
Sbjct: 3338 DAAEYSCVCGEER----TSASLTI------RPMPAHFIGRLRHQESIEGATATLRCEL-S 3386
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ P + W K + + DG + VC L I D+G Y+C
Sbjct: 3387 KAAP-VEWRKGRESL-RDGDRHSLRQDGAVCELQICGLAVADAGEYSC 3432
Score = 45.6 bits (103), Expect = 0.003
Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 11/188 (5%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISS-SDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+P F T L G +L C + + S V W + GV L KY + L
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATREL 4126
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ D+ EY+C G T+A+L+V P T R + D A+ ++
Sbjct: 4127 LIHQLEAKDTGEYACV----TGGQKTAASLRV-----TEP-EVTIVRGLVDAEVTADEDV 4176
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C + + W + S+ + + L + TPED+GT + N
Sbjct: 4177 EFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGN 4236
Query: 2772 SVWTDQIT 2779
+ Q+T
Sbjct: 4237 HASSAQLT 4244
Score = 45.2 bits (102), Expect = 0.004
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 13/184 (7%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN 2655
F + L+ A EG C V+S SD V W+R+G LL K+ +L + +
Sbjct: 1901 FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISD 1959
Query: 2656 AVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLEC 2715
V D+ + TVE E GA S+SA L+V + P F + + + + LE
Sbjct: 1960 LVLEDAGQ--ITVEAE-GA-SSSAALRVREA------PVLFKKKLEPQTVEERSSVTLEV 2009
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ +P P++ W ++ + + G+ + RL + N D G + C+ +
Sbjct: 2010 ELT-RPWPELRWTRNATAL-APGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ 2067
Query: 2776 DQIT 2779
++T
Sbjct: 2068 AKLT 2071
Score = 45.2 bits (102), Expect = 0.004
Identities = 51/205 (24%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 2569 RSKAFSEARSVISEKRTLSRNST-----RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP 2623
R A S+A V+ R L+ ++ R L D+ G V+L C + + P
Sbjct: 2797 REAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2624 TVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
V W ++ + KY + L + A D+ EY+C VE A ++A+L V
Sbjct: 2857 -VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE----ASKSTASLHV 2911
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
FT + + + V C+ P +TW K ++ + G++Q
Sbjct: 2912 EEKANC------FTEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQP- 2963
Query: 2744 YLADGV-CRLAIDNPTPEDSGTYTC 2767
+G+ RL I DS TYTC
Sbjct: 2964 -SQEGLTLRLTISALEKADSDTYTC 2987
Score = 44.8 bits (101), Expect = 0.006
Identities = 49/192 (25%), Positives = 79/192 (41%), Gaps = 19/192 (9%)
Query: 2579 VISEKRTLSRNSTRKPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
V ++RT S T + + + F+ D + A EG+ L C ++S+ P V W + L
Sbjct: 3521 VCGQERT-SATLTIRALPARFIEDVKNQEAREGATAVLQCE-LNSAAP-VEWRKGSETLR 3577
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT 2695
+ +Y + L++ +D+ EYSC E TSA L V +P
Sbjct: 3578 DGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQER----TSAMLTV------RALPIK 3627
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
FT +R+ VL C + + + W+K + + DG + C L I
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETL-RDGDRHSLRQDGARCELQIR 3684
Query: 2756 NPTPEDSGTYTC 2767
ED+G Y C
Sbjct: 3685 GLVAEDAGEYLC 3696
Score = 44.8 bits (101), Expect = 0.006
Identities = 19/66 (28%), Positives = 35/66 (53%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+VE+ + +T P +PP + + P+F+ + ++ E ++G V +C V G P P
Sbjct: 5097 RVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPS 5156
Query: 3415 VYWLRD 3420
V W +D
Sbjct: 5157 VRWFKD 5162
Score = 44.8 bits (101), Expect = 0.006
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 6097 STLGKILVQVPPRFVNKVLAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 6156 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 43.2 bits (97), Expect = 0.017
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 32/226 (14%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V+W KDG + + L + DD G+YE +R G ++ +
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAYQLSV--- 791
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+G+ ++ + + + G EA+ V V WY+DG+ L S +
Sbjct: 792 QGLARFLHKDMAGSC--VDAVAGGPAQFECETSEAH--VHVHWYKDGMELGHSGERFLQE 847
Query: 3319 DRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
D + L A VT +D G Y+C VG S ++ V SEP+ V
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV------SEPK---------V 888
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
++KE + RK +A G + + CE V + +V W +D K+
Sbjct: 889 VFAKEQLARRK---LQAEAGASATLSCE-VAQAQTEVTWYKDGKKL 930
Score = 42.7 bits (96), Expect = 0.022
Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 14/187 (7%)
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR-MTSQFNGFDCCLTIKDINIDDEGRYSC 3124
E L C + +P V W+K+G VE AG+ M G LTI D+G Y C
Sbjct: 2181 EKVTLECELS-RPNVDVRWLKDG--VELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC 2237
Query: 3125 EATNTHGKAS------TYA---RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+A + AS TY R + D + A+ R+ + P LR
Sbjct: 2238 DAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR 2297
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D+ + L CQV +V W+K +E+ + D + L I+ + +D
Sbjct: 2298 DKIAMEKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDE 2356
Query: 3236 GVYEVTA 3242
Y A
Sbjct: 2357 DTYTCDA 2363
Score = 42.3 bits (95), Expect = 0.030
Identities = 67/274 (24%), Positives = 110/274 (40%), Gaps = 43/274 (15%)
Query: 2618 ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAIST 2677
+S VTW ++G L KY + G L V + D+ Y C + G I+
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAY 787
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
+++ F + S D +A EC + + W+KD ++
Sbjct: 788 QLSVQGLARF----LHKDMAGSCVDA--VAGGPAQFECE-TSEAHVHVHWYKDGMELGHS 840
Query: 2738 GRYQAFYLAD-GV-CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNV 2795
G + F D G RL T +D GTY+C+ V D V+F R S+ P V
Sbjct: 841 G--ERFLQEDVGTRHRLVAATVTRQDEGTYSCR----VGEDS----VDFRLRVSE--PKV 888
Query: 2796 VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEV 2855
V A K ++AR+ L Q G + L E+ T V W ++G+ ++
Sbjct: 889 VFA-KEQLARRKL--------------QAEAGASATLSCEVAQAQTEVTWYKDGKKLSS- 932
Query: 2856 YRNARVFVEQGLYT--LALSDVTETESGLYTCRA 2887
+++V +E T L + + ++G Y+C A
Sbjct: 933 --SSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 42.3 bits (95), Expect = 0.030
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 17/170 (10%)
Query: 2606 VEGSRVKLTC--SVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+EG C S S+SDP + W G + + +++ L V A PSD+ E
Sbjct: 2748 LEGESCSFECVLSHESASDPAM-WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE 2806
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
+V +++ A+L V P + + D + ++ L C + P
Sbjct: 2807 VVFSVRG----LTSKASLIVRER------PAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENS 2772
+ W KD K I +Y + +G + L I + +D+G YTC+ E S
Sbjct: 2857 -VHWLKDRKAIRKSQKYDV--VCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Score = 42.3 bits (95), Expect = 0.030
Identities = 74/294 (25%), Positives = 110/294 (37%), Gaps = 46/294 (15%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K G E R + + +G C L I +++ D G YSC
Sbjct: 3816 GATAVLQCELS-KAAP-VEWRK-GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC 3872
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
G+ T A L V R+ + P F L+ + +
Sbjct: 3873 VC----GQERTSATLTV----------------RAPQ------PVFREPLQSLQAEEGST 3906
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C+ + P V W K G ++ + RR Q T E+ +L R
Sbjct: 3907 ATLQCE-LSEPTATVVWSKGGLQLQANGRREPRL--QGCTAELVLQDLQ---------RE 3954
Query: 3245 NSGAVSCHCGLVVDKG-IRAYVAP-EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
++G +C CG + AP F L+ ++ EG + + V W
Sbjct: 3955 DTGEYTCTCGSQATSATLTVTAAPVRFLRELQH-QEVDEGGTAHLCCELSR-AGASVEWR 4012
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ ++L P + M D EL + V DAG YTC + AS S +V
Sbjct: 4013 KGSLQLFPCAKYQMVQD-GAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/174 (25%), Positives = 64/174 (36%), Gaps = 4/174 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
P + VV ++ V+L+W + Y+VE GA G R + P
Sbjct: 4526 PEDAEVVAHSSHTVTLSWAAPMSDGGGGLCGYRVEV-KEGATGQWRLCH-ELVPGPECVV 4583
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANL 3070
L GE Y FRV G GE ++ + P ++ AGE +L
Sbjct: 4584 DGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSL 4643
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
V + V+W K G E + GR G L IK +D+G Y C
Sbjct: 4644 ELEVVAE-AGEVIWHK-GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 41.5 bits (93), Expect = 0.052
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 3/135 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + V+ G L +I G PT +V W ++ + VT R R+ + LY
Sbjct: 7 SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGAR-FRLAQDGDLY 65
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
L + D+ +SG Y CRA +A G + V + + + RP I + G
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREG 124
Query: 2929 EDINISFRTQGEPKP 2943
+ R G P+P
Sbjct: 125 SEATFRCRVGGSPRP 139
Score = 41.5 bits (93), Expect = 0.052
Identities = 66/284 (23%), Positives = 101/284 (35%), Gaps = 34/284 (11%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+AG A C V V W K+G E+ R + G L + DEG Y
Sbjct: 810 VAGGPAQFECETSEAHVH-VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTY 868
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
SC G+ S RL V + V+ + +R+ AE A
Sbjct: 869 SCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQAE-------------------AG 905
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L+C+V +V+WYKDG+++ + L + D G Y A
Sbjct: 906 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+S H + K + A + E + G +S V A V WY
Sbjct: 965 --GGQRLSFHLDV---KEPKVVFAKDQVAHSE--VQAEAGANATLSCEV-AQAQAEVMWY 1016
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+DG +L S + + + + L + DAG Y+C A +
Sbjct: 1017 KDGKKLSSSLK-VHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Score = 41.5 bits (93), Expect = 0.052
Identities = 68/284 (23%), Positives = 110/284 (38%), Gaps = 39/284 (13%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AG +A L+C V + V W K+G ++ + ++ + G L ++ D G YS
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSS-KVRVEAVGCTRRLVVQQAGQADAGEYS 1697
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
CEA G+ ++ RL V E + ++ ER E P D
Sbjct: 1698 CEAG---GQRLSF-RLHVA------ELEPQIS-ERPCRRE----PLVVKEHED------- 1735
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
+ LT + V+W KDG E+ KR HTL + + D +Y
Sbjct: 1736 -IILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRV- 1793
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG-VTWY 3302
GA + V++ VA +FC LEP+ G ++ E P+ V W
Sbjct: 1794 ---GAEGQDFPVQVEE-----VAAKFCRLLEPVCGELGG---TVTLACELSPACAEVVWR 1842
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ R +R M + + L + + DAG Y C + ++
Sbjct: 1843 CGNTQPRVGKRFQMVAEGPVR-SLTVLGLRAEDAGEYVCESRDD 1885
Score = 41.5 bits (93), Expect = 0.052
Identities = 45/171 (26%), Positives = 64/171 (37%), Gaps = 13/171 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLITLEVLNAVP 2658
L D EGS C + ++ V W+ + L N+L G L +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
DS T+ E G SA L+V P F+R + D +L L C
Sbjct: 3071 KDSG----TIYFEAGDQRASAALRVTEK------PSVFSRELTDATITEGEDLTLVCETS 3120
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+P + W KD K + R Q + +L I T +DSG Y C+A
Sbjct: 3121 TCDIP-MCWTKDGKTLRGSARCQLSHEGHRA-QLLITGATLQDSGRYKCEA 3169
Score = 41.1 bits (92), Expect = 0.068
Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 14/174 (8%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E + LT ++ + S TVTW ++GV + ++ TL V A DSA YSC
Sbjct: 1732 EHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
V E + +P + + F R + + L C + ++
Sbjct: 1792 RVGAEG---------QDFP-VQVEEVAAKFCRLLEPVCGELGGTVTLACEL-SPACAEVV 1840
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
W + Q R+Q +A+G R L + ED+G Y C++ + + Q+T
Sbjct: 1841 WRCGNTQPRVGKRFQ--MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLT 1892
Score = 41.1 bits (92), Expect = 0.068
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 8/126 (6%)
Query: 2690 SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK-ITWFKDDKQIPSDGRYQAFYLADG 2748
S IP TR + +VL C R P PK + W+KDD + +++ L
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFR--PAPKAVQWYKDDTPLSPSEKFK-MSLEGQ 2521
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
+ L I P D+G Y C+A ++ + ++T RE V+ + AE T S
Sbjct: 2522 MAELRILRLMPADAGVYRCQAGSAHSSTEVT----VEAREVTVTGPLQDAEATEEGWASF 2577
Query: 2809 ESRRPH 2814
H
Sbjct: 2578 SCELSH 2583
Score = 41.1 bits (92), Expect = 0.068
Identities = 43/181 (23%), Positives = 68/181 (37%), Gaps = 11/181 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D EG C + +S W GV L + G + L L+ V
Sbjct: 4256 LQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTL 4315
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+ A TV G S+ A LKV T R + + L E + EC++
Sbjct: 4316 EDAG---TVSFHVGTCSSEAQLKVTAK-------NTVVRGLENVEALEGGEALFECQLSQ 4365
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENSVWTDQI 2778
+ TW DD+ + + + + +G+ L + N P+DS T A + V + +
Sbjct: 4366 PEVAAHTWLLDDEPVRTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFL 4425
Query: 2779 T 2779
T
Sbjct: 4426 T 4426
Score = 40.3 bits (90), Expect = 0.12
Identities = 92/365 (25%), Positives = 137/365 (37%), Gaps = 78/365 (21%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G TA L C + K P V W K GHE + R + + +G C L I+ + +D G Y C
Sbjct: 3640 GATAVLRCELS-KMAP-VEWWK-GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC 3696
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
GK T A L V R + P +F LR+
Sbjct: 3697 MC----GKERTSAMLTV---RAM-------------------PSKFIEGLRNEEATEGDT 3730
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C++ + P V W K E + R + QD L+I + D G Y
Sbjct: 3731 ATLWCELSKAAP--VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEY------ 3782
Query: 3245 NSGAVSCHCG---LVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
SC CG +RA A F +E + + E + V W
Sbjct: 3783 -----SCVCGQERTSATLTVRALPA-RF---IEDVKNQEAREGATAVLQCELSKAAPVEW 3833
Query: 3302 YRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ LR R +L +DG + EL + ++ D G Y+C G+ TS + V
Sbjct: 3834 RKGSETLRGGDR--YSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV-- 3885
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R P P +EP+ +S +A EG T ++CE + +P V W +
Sbjct: 3886 -------RAPQ-------PVFREPL-----QSLQAEEGSTATLQCE-LSEPTATVVWSKG 3925
Query: 3421 FLKVR 3425
L+++
Sbjct: 3926 GLQLQ 3930
Score = 39.1 bits (87), Expect = 0.28
Identities = 68/307 (22%), Positives = 115/307 (37%), Gaps = 43/307 (14%)
Query: 2593 KPV-FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
KPV F L D +A E + L C V S + V W ++GV L KY G L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
V + P D+ Y+C V G+ T A ++V+ + T+ ++ L
Sbjct: 2704 VVHDVSPEDAGLYTCHV----GSEETRARVRVH------DLHVGITKRLKTMEVLEGESC 2753
Query: 2712 VLECRIRGQPL-PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
EC + + W K + S R+QA L + P D+G
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYI-LVVREAAPSDAGE------ 2806
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
V F+ R +++ E+ + LE D VA G +
Sbjct: 2807 -----------VVFSVRGLTSKASLIVRERPAAIIKPLE-----------DQWVAPGEDV 2844
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ E+ T V WL++ +++ + + V E + L + + ++G YTC ++
Sbjct: 2845 ELRCELSRAGTPVHWLKDRKAIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS 2903
Query: 2891 HGNVDMN 2897
++
Sbjct: 2904 KSTASLH 2910
Score = 38.7 bits (86), Expect = 0.36
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P V W +DGV+L PS + L G L + V+ DAG+YTC +E RA
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDF-LHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRA 2727
Score = 37.9 bits (84), Expect = 0.64
Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
V WY+D L PS + M+L +GQ+ EL + + DAGVY C A + +ST VE
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSL--EGQMAELRILRLMPADAGVYRCQAGS--AHSSTEVTVE 2554
Score = 37.5 bits (83), Expect = 0.84
Identities = 13/41 (31%), Positives = 23/41 (56%)
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+S P F+ +P++ G + C++VG+P P V W +D
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKD 46
Score = 37.5 bits (83), Expect = 0.84
Identities = 46/178 (25%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+ +R + VQA +T V + W+ DG+ + + D HTL I
Sbjct: 611 PKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTI 670
Query: 3228 --APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
P +L G + A N S + G+ A P E L +LHE +L
Sbjct: 671 REVPASL-HGAQLKFVA--NGIESSIRMEVRAAPGLTAN-KPPAAAAREVLARLHEEAQL 726
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTA 3343
+A VTW +DG L P + + G+ L + V DAG+Y C +
Sbjct: 727 LAELSDQA---AAVTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECVS 780
Score = 35.9 bits (79), Expect = 2.6
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLL--DNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
EGS C V S P V+W ++G L + + R + + L + A P D Y
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 2665 SCTVENENGAISTSANLKV 2683
EN GA S +A L V
Sbjct: 183 EVRAENPLGAASAAAALVV 201
Score = 35.9 bits (79), Expect = 2.6
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 3050 PEFVDILPGQLKILA--GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
P V + G ++A G A C V V VVW ++G ++ SQ +G
Sbjct: 1896 PRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-AVVWFRDGALLQPSEKFAISQ-SGASH 1953
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
LTI D+ ++D G+ + EA A+ R A V
Sbjct: 1954 SLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Score = 35.5 bits (78), Expect = 3.4
Identities = 40/168 (23%), Positives = 65/168 (38%), Gaps = 14/168 (8%)
Query: 3185 VRLTCQVIGSPP-PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V L C++ SP +V W + KR + +L + +D G Y +R
Sbjct: 1826 VTLACEL--SPACAEVVWRCGNTQPRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESR 1883
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
++ S + V + ++ F GL + EG E VV V V W+R
Sbjct: 1884 DDH--TSAQLTVSVPRVVK------FMSGLSTVVA-EEGGEATFQCVVSP-SDVAVVWFR 1933
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
DG L+PS + ++ L ++ + DAG T A A+
Sbjct: 1934 DGALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSAA 1980
Score = 35.5 bits (78), Expect = 3.4
Identities = 43/195 (22%), Positives = 73/195 (37%), Gaps = 19/195 (9%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
P L D+ V V L C++ + P V W KD + + ++ + + L
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLV 2884
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-EGDEL 3285
I +L D G Y + S H V + C E L L E
Sbjct: 2885 IRGASLKDAGEYTCEVEASKSTASLH------------VEEKANCFTEELTNLQVEEKGT 2932
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ +P+ VTW + + LR S + + L ++A+ D+ YTC
Sbjct: 2933 AVFTCKTEHPAATVTWRKGLLELRASGKH-QPSQEGLTLRLTISALEKADSDTYTC---- 2987
Query: 3346 EVGRASTSGKVEVIG 3360
++G+A + ++ V G
Sbjct: 2988 DIGQAQSRAQLLVQG 3002
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 6008 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 6056
Score = 35.1 bits (77), Expect = 4.5
Identities = 21/65 (32%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GE L C +P + W K+G + A R G L I + D GR
Sbjct: 3107 ITEGEDLTLVCETSTCDIP-MCWTKDGKTLRGSA-RCQLSHEGHRAQLLITGATLQDSGR 3164
Query: 3122 YSCEA 3126
Y CEA
Sbjct: 3165 YKCEA 3169
Score = 34.3 bits (75), Expect = 7.9
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Query: 2804 ARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFV 2863
AR + + F L D GT+ LQ E+ V W ++G + + +
Sbjct: 2638 ARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWS 2889
G L + DV+ ++GLYTC S
Sbjct: 2698 -AGTRGLVVHDVSPEDAGLYTCHVGS 2722
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 102 bits (244), Expect = 3e-20
Identities = 98/370 (26%), Positives = 153/370 (41%), Gaps = 60/370 (16%)
Query: 3057 PGQLKILAGETANLTC-SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
PG + + GE A L C +G P P V W K+G ++EE GR+T + T+K
Sbjct: 172 PGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKS-- 229
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
D G Y C A+N G+ + A +V +R P F R
Sbjct: 230 --DAGMYVCVASNMAGERESAAAEVMVLER----------------------PSFLRRPV 265
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
++ V A PV C+V G PPP++ W K+ E+ +Y+ H+L I + +D
Sbjct: 266 NQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL----PTGRYEIRSDHSLWIGHVSAEDE 321
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAY 3294
G Y A N+ G L V +V P+ +P ++ G+ + +
Sbjct: 322 GTYTCVAENSVGRAEASGSLSV------HVPPQLV--TQPQDQMAAPGESVAFQCETKGN 373
Query: 3295 PSVGVTWYRDG--VRLRPSRRAIMT--LDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P + W ++G V L PS+ T + +L + AV DAG Y C A + G
Sbjct: 374 PPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSI 433
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+E+ G S +PPV+ ++ P + G +V + C V G+
Sbjct: 434 LAKALLEIKG---ASLDGLPPVI-------------LQGPANQTLVLGSSVWLPCRVTGN 477
Query: 3411 PKPDVYWLRD 3420
P+P V W +D
Sbjct: 478 PQPSVRWKKD 487
Score = 85.4 bits (202), Expect = 3e-15
Identities = 85/328 (25%), Positives = 148/328 (45%), Gaps = 48/328 (14%)
Query: 2622 DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI-STSAN 2680
+P+V+W ++G L + + R + G + + + + SD+ Y C N G S +A
Sbjct: 195 EPSVSWRKDGARLKEE-EGRITIRGGKLMMS--HTLKSDAGMYVCVASNMAGERESAAAE 251
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
+ V P+F R + LA+ + C ++G P P++ W K+D ++P+ GRY
Sbjct: 252 VMVLER-------PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPT-GRY 303
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
+ +D L I + + ED GTYTC AENSV + + ++ V P +VT +
Sbjct: 304 E--IRSDH--SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-----HVPPQLVTQPQ 354
Query: 2801 TRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSV----TEV 2855
D A G ++ Q E +G P + W +EG V ++
Sbjct: 355 --------------------DQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQS 394
Query: 2856 YRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVI 2915
+ F L ++ V ++G Y C+A S G++ + A+ ++ + LDG P VI
Sbjct: 395 LQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSI-LAKALLEIKGASLDGLPPVI 453
Query: 2916 VGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P L+ +G + + R G P+P
Sbjct: 454 LQGPANQTLV-LGSSVWLPCRVTGNPQP 480
Score = 82.6 bits (195), Expect = 2e-14
Identities = 83/334 (24%), Positives = 128/334 (38%), Gaps = 43/334 (12%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP F+ Q+ +LA C VKG P P + W K E+ + S D
Sbjct: 256 ERPSFLRRPVNQV-VLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRS-----DH 309
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I ++ +DEG Y+C A N+ G+A L+V P
Sbjct: 310 SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-----------------------HVP 346
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--- 3224
PQ + +D+ V C+ G+PPP + W K+G +V+ ++ +F
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406
Query: 3225 --LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
L I D G Y A + +G++ L + KG P L G
Sbjct: 407 GQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEI-KGASLDGLPPVILQGPANQTLVLG 465
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
+ + V P V W +DG L+ T+ L +A V D G Y+C
Sbjct: 466 SSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANG---TLYIANVQEMDMGFYSCV 522
Query: 3343 ASNEVGRASTSGKVEV-----IGTDQTSEPRIPP 3371
A + G A+ SG +++ + D +EP PP
Sbjct: 523 AKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPP 556
Score = 75.8 bits (178), Expect = 3e-12
Identities = 102/404 (25%), Positives = 156/404 (38%), Gaps = 69/404 (17%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV 3091
G+ S S +G A P V+ P L + GE A L C +G+P P + W KNG V
Sbjct: 48 GDPSLNGSRVGPEDA--MPRIVE-QPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARV 104
Query: 3092 -----EEEAGRMTSQFNGFDCCLTIKDINI-DDEGRYSCEATNTHGKA-STYARLAVVTD 3144
+ A R+ + DEG Y+C A N G A S A L V
Sbjct: 105 ATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVL 164
Query: 3145 RTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD 3204
R + P + + + V P R G P P VSW KD
Sbjct: 165 RDDFRQS---------------PGNVVVAVGEPAVLECVPPR------GHPEPSVSWRKD 203
Query: 3205 GEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
G + ++ R + + L ++ T D G+Y A N +G V+
Sbjct: 204 GARLKEEEGRITIRGGK---LMMSHTLKSDAGMYVCVASNMAGERESAAAEVM-----VL 255
Query: 3265 VAPEFCCGLEPLYKLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQ 3323
P F P+ ++ D + V+ P + W ++ L P+ R + D
Sbjct: 256 ERPSFL--RRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL-PTGRYEIRSDHS-- 310
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
L + V+ D G YTC A N VGRA SG + V +PP +++
Sbjct: 311 --LWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV---------HVPPQLVT-------- 351
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRIF 3427
+P+ A G++V +CE G+P P ++W ++ +V +F
Sbjct: 352 -----QPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLF 390
Score = 62.5 bits (145), Expect = 3e-08
Identities = 105/478 (21%), Positives = 172/478 (35%), Gaps = 75/478 (15%)
Query: 2570 SKAFSEARSVISEKRTLSRNS-TRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
S E S +E L R S R+PV L D + V C V P + W
Sbjct: 239 SNMAGERESAAAEVMVLERPSFLRRPVNQVVLAD------APVTFLCEVKGDPPPRLRWR 292
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
+ D +L + + +L + + D Y+C EN G S +L V+
Sbjct: 293 KE----DGELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVH---- 344
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI---PSDG-RYQAFY 2744
+PP +D + +C +G P P I W K+ Q+ PS + +
Sbjct: 345 ---VPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRF 401
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
+L I D+G Y C+A + V+ +++ I
Sbjct: 402 SVSPRGQLNITAVQRGDAGYYVCQAVS-------------------VAGSILAKALLEIK 442
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
SL+ P + + G ++ L + G P V W ++G+ + + F
Sbjct: 443 GASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQ---WLQGDDLQFK 499
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
TL +++V E + G Y+C A S+ G +
Sbjct: 500 TMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSG------------------------- 534
Query: 2924 LISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYK 2983
+ + ED +S EP + P P +P V + N ++L W K +PQT A V +Y
Sbjct: 535 WLKMREDWGVSPDPPTEP---SSPPGAPSQPVVTEITKNSITLTW-KPNPQTGAAVTSYV 590
Query: 2984 VESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
+E++ A R V G+ L + L+ Y F V +G E S S +
Sbjct: 591 IEAFSPAAGNTWRTVADGV-QLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPV 647
Score = 58.0 bits (134), Expect = 6e-07
Identities = 81/352 (23%), Positives = 132/352 (37%), Gaps = 57/352 (16%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVL--- 2654
D G L C P + WY+NG + ++ +R L G + +
Sbjct: 72 DLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHG 131
Query: 2655 NAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
D Y+C N GA + S N S E + + F +S + VLE
Sbjct: 132 RRARPDEGVYTCVARNYLGA-AASRN----ASLEVAVLRDDFRQSPGNVVVAVGEPAVLE 186
Query: 2715 C-RIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C RG P P ++W KD ++ +GR + G +L + + D+G Y C A
Sbjct: 187 CVPPRGHPEPSVSWRKDGARLKEEEGR---ITIRGG--KLMMSHTLKSDAGMYVCVAS-- 239
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
N G + V+ E+ RRP VL D V
Sbjct: 240 ----------NMAGERESAAAEVMVLERPSFL------RRPVNQVVLADAPVT------F 277
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
E++G P R+ W +E + R + ++L + V+ + G YTC A ++
Sbjct: 278 LCEVKGDPPPRLRWRKEDGELP----TGRYEIRSD-HSLWIGHVSAEDEGTYTCVAENSV 332
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G + + +++V P L +P +D + + GE + T+G P P
Sbjct: 333 GRAEASGSLSVHVPPQLVTQP--------QDQMAAPGESVAFQCETKGNPPP 376
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens cDNA
FLJ31982 fis, clone NT2RP7008550, highly similar to Mus
musculus rig-1 protein mRNA. ).
Length = 1034
Score = 101 bits (243), Expect = 3e-20
Identities = 98/370 (26%), Positives = 153/370 (41%), Gaps = 60/370 (16%)
Query: 3057 PGQLKILAGETANLTC-SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
PG + + GE A L C +G P P V W K+G ++EE GR+T + T+K
Sbjct: 172 PGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKS-- 229
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
D G Y C A+N G+ + A +V +R P F R
Sbjct: 230 --DAGMYVCVASNMAGERESAAAEVMVLER----------------------PSFLRRPV 265
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
++ V A PV C+V G PPP++ W K+ E+ +Y+ H+L I + +D
Sbjct: 266 NQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL----PTGRYEIRSDHSLWIGHVSAEDE 321
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAY 3294
G Y A N+ G L V +V P+ +P ++ G+ + +
Sbjct: 322 GTYTCVAENSVGRAEASGSLSV------HVPPQLV--TQPQDQMAAPGESVAFQCETKGN 373
Query: 3295 PSVGVTWYRDG--VRLRPSRRAIMT--LDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P + W ++G V L PS+ T + +L + AV DAG Y C A + G
Sbjct: 374 PPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGSI 433
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+E+ G S +PPV+ ++ P + G +V + C V G+
Sbjct: 434 LAKALLEIKG---ASLDGLPPVI-------------LQGPANQTLVLGSSVWLPCRVTGN 477
Query: 3411 PKPDVYWLRD 3420
P+P V W +D
Sbjct: 478 PQPSVRWKKD 487
Score = 85.0 bits (201), Expect = 4e-15
Identities = 85/328 (25%), Positives = 148/328 (45%), Gaps = 48/328 (14%)
Query: 2622 DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI-STSAN 2680
+P+V+W ++G L + + R + G + + + + SD+ Y C N G S +A
Sbjct: 195 EPSVSWRKDGARLKEE-EGRITIRGGKLMMS--HTLKSDAGMYVCVASNMAGERESAAAE 251
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
+ V P+F R + LA+ + C ++G P P++ W K+D ++P+ GRY
Sbjct: 252 VMVLER-------PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPT-GRY 303
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
+ +D L I + + ED GTYTC AENSV + + ++ V P +VT +
Sbjct: 304 E--IRSDH--SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-----HVPPQLVTQPQ 354
Query: 2801 TRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSV----TEV 2855
D A G ++ Q E +G P + W +EG V ++
Sbjct: 355 --------------------DQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQS 394
Query: 2856 YRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVI 2915
+ F L ++ V ++G Y C+A S G++ + A+ ++ + LDG P VI
Sbjct: 395 LQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGSI-LAKALLEIKGASLDGLPPVI 453
Query: 2916 VGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P L+ +G + + R G P+P
Sbjct: 454 LQGPANQTLV-LGSSVWLPCRVTGNPQP 480
Score = 82.6 bits (195), Expect = 2e-14
Identities = 83/334 (24%), Positives = 128/334 (38%), Gaps = 43/334 (12%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP F+ Q+ +LA C VKG P P + W K E+ + S D
Sbjct: 256 ERPSFLRRPVNQV-VLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRS-----DH 309
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I ++ +DEG Y+C A N+ G+A L+V P
Sbjct: 310 SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-----------------------HVP 346
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--- 3224
PQ + +D+ V C+ G+PPP + W K+G +V+ ++ +F
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406
Query: 3225 --LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
L I D G Y A + +G++ L + KG P L G
Sbjct: 407 GQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEI-KGASLDGLPPVILQGPANQTLVLG 465
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
+ + V P V W +DG L+ T+ L +A V D G Y+C
Sbjct: 466 SSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANG---TLYIANVQEMDMGFYSCV 522
Query: 3343 ASNEVGRASTSGKVEV-----IGTDQTSEPRIPP 3371
A + G A+ SG +++ + D +EP PP
Sbjct: 523 AKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPP 556
Score = 75.8 bits (178), Expect = 3e-12
Identities = 102/404 (25%), Positives = 156/404 (38%), Gaps = 69/404 (17%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV 3091
G+ S S +G A P V+ P L + GE A L C +G+P P + W KNG V
Sbjct: 48 GDPSLNGSRVGPEDA--MPRIVE-QPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARV 104
Query: 3092 -----EEEAGRMTSQFNGFDCCLTIKDINI-DDEGRYSCEATNTHGKA-STYARLAVVTD 3144
+ A R+ + DEG Y+C A N G A S A L V
Sbjct: 105 ATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVL 164
Query: 3145 RTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD 3204
R + P + + + V P R G P P VSW KD
Sbjct: 165 RDDFRQS---------------PGNVVVAVGEPAVLECVPPR------GHPEPSVSWRKD 203
Query: 3205 GEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
G + ++ R + + L ++ T D G+Y A N +G V+
Sbjct: 204 GARLKEEEGRITIRGGK---LMMSHTLKSDAGMYVCVASNMAGERESAAAEVM-----VL 255
Query: 3265 VAPEFCCGLEPLYKLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQ 3323
P F P+ ++ D + V+ P + W ++ L P+ R + D
Sbjct: 256 ERPSFL--RRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL-PTGRYEIRSDHS-- 310
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
L + V+ D G YTC A N VGRA SG + V +PP +++
Sbjct: 311 --LWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV---------HVPPQLVT-------- 351
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRIF 3427
+P+ A G++V +CE G+P P ++W ++ +V +F
Sbjct: 352 -----QPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLF 390
Score = 62.1 bits (144), Expect = 3e-08
Identities = 105/478 (21%), Positives = 172/478 (35%), Gaps = 75/478 (15%)
Query: 2570 SKAFSEARSVISEKRTLSRNS-TRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
S E S +E L R S R+PV L D + V C V P + W
Sbjct: 239 SNMAGERESAAAEVMVLERPSFLRRPVNQVVLAD------APVTFLCEVKGDPPPRLRWR 292
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
+ D +L + + +L + + D Y+C EN G S +L V+
Sbjct: 293 KE----DGELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVH---- 344
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI---PSDG-RYQAFY 2744
+PP +D + +C +G P P I W K+ Q+ PS + +
Sbjct: 345 ---VPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRF 401
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
+L I D+G Y C+A + V+ +++ I
Sbjct: 402 SVSPRGQLNITAVQRGDAGYYMCQAVS-------------------VAGSILAKALLEIK 442
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
SL+ P + + G ++ L + G P V W ++G+ + + F
Sbjct: 443 GASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQ---WLQGDDLQFK 499
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
TL +++V E + G Y+C A S+ G +
Sbjct: 500 TMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSG------------------------- 534
Query: 2924 LISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYK 2983
+ + ED +S EP + P P +P V + N ++L W K +PQT A V +Y
Sbjct: 535 WLKMREDWGVSPDPPTEP---SSPPGAPSQPVVTEITKNSITLTW-KPNPQTGAAVTSYV 590
Query: 2984 VESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
+E++ A R V G+ L + L+ Y F V +G E S S +
Sbjct: 591 IEAFSPAAGNTWRTVADGV-QLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPV 647
Score = 58.0 bits (134), Expect = 6e-07
Identities = 81/352 (23%), Positives = 132/352 (37%), Gaps = 57/352 (16%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVL--- 2654
D G L C P + WY+NG + ++ +R L G + +
Sbjct: 72 DLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHG 131
Query: 2655 NAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
D Y+C N GA + S N S E + + F +S + VLE
Sbjct: 132 RRARPDEGVYTCVARNYLGA-AASRN----ASLEVAVLRDDFRQSPGNVVVAVGEPAVLE 186
Query: 2715 C-RIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
C RG P P ++W KD ++ +GR + G +L + + D+G Y C A
Sbjct: 187 CVPPRGHPEPSVSWRKDGARLKEEEGR---ITIRGG--KLMMSHTLKSDAGMYVCVAS-- 239
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
N G + V+ E+ RRP VL D V
Sbjct: 240 ----------NMAGERESAAAEVMVLERPSFL------RRPVNQVVLADAPVT------F 277
Query: 2833 QVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
E++G P R+ W +E + R + ++L + V+ + G YTC A ++
Sbjct: 278 LCEVKGDPPPRLRWRKEDGELP----TGRYEIRSD-HSLWIGHVSAEDEGTYTCVAENSV 332
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G + + +++V P L +P +D + + GE + T+G P P
Sbjct: 333 GRAEASGSLSVHVPPQLVTQP--------QDQMAAPGESVAFQCETKGNPPP 376
>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
Length = 1040
Score = 99 bits (238), Expect = 1e-19
Identities = 142/603 (23%), Positives = 224/603 (37%), Gaps = 64/603 (10%)
Query: 2802 RIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNAR 2860
++ ++ + P F + D + G + L+ + R WL++G +T+ +
Sbjct: 458 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 517
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPE 2920
+ G +L ++ + ++G YTC+ + G V +A V+V E
Sbjct: 518 DQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSAC--------------VVVSGSE 563
Query: 2921 KDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVL 2980
+ S G +++ +FR + + P E V ++S ++P+ A
Sbjct: 564 SEAESSSGGELDDAFRRAARRLHRLFRTKSPAE---VSDEELFLSADEGPAEPEEPADWQ 620
Query: 2981 AYKVESWLIGAEGGARW-VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
Y+ + I A +T A L G E R S +T +
Sbjct: 621 TYREDEHFICIRFEALTEARQAVTRFQEMFA-TLGIGVEIKLVEQGPRRVEMCISKETPA 679
Query: 3040 SIGVG------LAGDR-PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
+ L D P F+ L Q ++ G + C V G+P+P V W K+G +E
Sbjct: 680 PVVPPEPLPSLLTSDAAPVFLTELQNQ-EVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE 738
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--A 3150
E+ M ++ L I + D G Y C A N+ G +ST A L V T ++ A
Sbjct: 739 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAA 798
Query: 3151 DA-------------KLKRER----SAEVEGDYPPQFTMRLRDRRV-QATYPVRLTCQVI 3192
DA RE+ S EG PQ LRD +V T + +V
Sbjct: 799 DATESSSYFSAQGYLSTSREQEGTESTTDEGQL-PQVVEELRDLQVAPGTRLAKFQLKVK 857
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCH 3252
G P P++ W+KDG+ + + HTLEI +D G Y N GA
Sbjct: 858 GYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSS 917
Query: 3253 CGLVV----------DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
L+V + + P K+ +G + S VE P V W
Sbjct: 918 ARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWL 977
Query: 3303 RD----GVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
R+ GV + P Q L L V + G YTC ASN G+A S +
Sbjct: 978 REEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLH 1037
Query: 3358 VIG 3360
V G
Sbjct: 1038 VSG 1040
Score = 82.6 bits (195), Expect = 2e-14
Identities = 75/286 (26%), Positives = 122/286 (42%), Gaps = 28/286 (9%)
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
PS S P F +++ + +C + GQP+P + WFKD K + D Y
Sbjct: 688 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 747
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--------QITHFVNFTGRESQVSPNVV 2796
G +L I P D G Y C AENS+ +T T ++ S +
Sbjct: 748 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 807
Query: 2797 TAE---KTRIARQSLES-----RRPHFGNVLTDYQVARGGTIG-LQVEIRGCPT-RVEWL 2846
+A+ T ++ ES + P L D QVA G + Q++++G P R+ W
Sbjct: 808 SAQGYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF 867
Query: 2847 REGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPS 2906
++G+ +T + R+ ++ L+TL + VT +SG Y +A G +A + V P
Sbjct: 868 KDGQPLT-ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD 926
Query: 2907 DLDGKPAVIVGR---PEKDI------LISVGEDINISFRTQGEPKP 2943
+ + KPA V P + + + G I S + +G P P
Sbjct: 927 EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVP 972
Score = 60.1 bits (139), Expect = 1e-07
Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
V+ YP+ + W++DG L S MT D+ L + +VT D+G Y SN +G A
Sbjct: 856 VKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTLEIISVTREDSGQYAAYISNAMGAA 914
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+S ++ V G D+ E + V VP P + + + ++G ++ +V G
Sbjct: 915 YSSARLLVRGPDEPEE-KPASDVHEQLVP----PRMLERFTPKKVKKGSSITFSVKVEGR 969
Query: 3411 PKPDVYWLRD 3420
P P V+WLR+
Sbjct: 970 PVPTVHWLRE 979
Score = 57.6 bits (133), Expect = 7e-07
Identities = 30/85 (35%), Positives = 42/85 (49%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD LR+ VV + V W +DGV L R + DG L + + DAG YTC
Sbjct: 483 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 542
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSE 3366
SN+ G+ + S V V G++ +E
Sbjct: 543 QVSNKFGQVTHSACVVVSGSESEAE 567
Score = 54.8 bits (126), Expect = 5e-06
Identities = 37/135 (27%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP F L+ ++ +G + VV P V W++DG L ++ D+ G +
Sbjct: 696 APVFLTELQN-QEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 754
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + AV D GVY C A N +G +ST ++ V D TS + Y
Sbjct: 755 LIITAVVPADMGVYRCLAENSMGVSSTKAELRV---DLTSTDYDTAADATESSSYFSAQG 811
Query: 3386 FIRKPRSSEAREGDT 3400
++ R E E T
Sbjct: 812 YLSTSREQEGTESTT 826
Score = 53.6 bits (123), Expect = 1e-05
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGL 2648
S PVF T L ++ +G V C V P+V W+++G LL+ Y + G
Sbjct: 693 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 752
Query: 2649 ITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
L + VP+D Y C EN G ST A L+V
Sbjct: 753 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 787
Score = 50.4 bits (115), Expect = 1e-04
Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRL 2752
P F+ + DT + L LEC + + + W KD ++ +DGR+ L DG C L
Sbjct: 469 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL-TDGRHHHIDQLGDGTCSL 527
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITH--FVNFTGRESQ 2790
I D+G YTC+ N Q+TH V +G ES+
Sbjct: 528 LITGLDRADAGCYTCQVSNKF--GQVTHSACVVVSGSESE 565
Score = 50.0 bits (114), Expect = 1e-04
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLE 2652
P+FS D A G ++L C V S +D W ++GV L D + + +L DG +L
Sbjct: 469 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 528
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSA 2679
+ +D+ Y+C V N+ G ++ SA
Sbjct: 529 ITGLDRADAGCYTCQVSNKFGQVTHSA 555
Score = 48.8 bits (111), Expect = 3e-04
Identities = 60/253 (23%), Positives = 101/253 (39%), Gaps = 21/253 (8%)
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRI 2717
+D+ E S + + G +STS + S P +RD L + ++
Sbjct: 798 ADATE-SSSYFSAQGYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV 856
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+G P P++ WFKD + + + + + D + L I + T EDSG Y N++
Sbjct: 857 KGYPAPRLYWFKDGQPLTASAHIR---MTDKKILHTLEIISVTREDSGQYAAYISNAMGA 913
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ + G + + + + LE P +V +G +I V+
Sbjct: 914 AYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPK--------KVKKGSSITFSVK 965
Query: 2836 IRGCPT-RVEWLREG--RSVTEVYRNA---RVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
+ G P V WLRE R V + + V ++L L DV G YTC A +
Sbjct: 966 VEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASN 1025
Query: 2890 AHGNVDMNAAITV 2902
A G +A++ V
Sbjct: 1026 AAGQALCSASLHV 1038
Score = 45.6 bits (103), Expect = 0.003
Identities = 43/190 (22%), Positives = 72/190 (37%), Gaps = 18/190 (9%)
Query: 2600 LTDRTAVEGSRV-KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVP 2658
L D G+R+ K V P + W+++G L R L TLE+++
Sbjct: 838 LRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTR 897
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASP----------IPPTFTRSIRDTFHLAE 2708
DS +Y+ + N GA +SA L V E +PP
Sbjct: 898 EDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKG 957
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQI------PSDGRYQAFYLADGVCRLAIDNPTPEDS 2762
+ + ++ G+P+P + W +++ + P Y A + +D +
Sbjct: 958 SSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD-VGRQHQ 1016
Query: 2763 GTYTCKAENS 2772
GTYTC A N+
Sbjct: 1017 GTYTCIASNA 1026
Score = 44.8 bits (101), Expect = 0.006
Identities = 19/66 (28%), Positives = 35/66 (53%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+VE+ + +T P +PP + + P+F+ + ++ E ++G V +C V G P P
Sbjct: 668 RVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPS 727
Query: 3415 VYWLRD 3420
V W +D
Sbjct: 728 VRWFKD 733
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/174 (25%), Positives = 64/174 (36%), Gaps = 4/174 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
P + VV ++ V+L+W + Y+VE GA G R + P
Sbjct: 97 PEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEV-KEGATGQWRLCH-ELVPGPECVV 154
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANL 3070
L GE Y FRV G GE ++ + P ++ AGE +L
Sbjct: 155 DGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSL 214
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
V + V+W K G E + GR G L IK +D+G Y C
Sbjct: 215 ELEVVAE-AGEVIWHK-GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 266
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 99 bits (238), Expect = 1e-19
Identities = 100/342 (29%), Positives = 151/342 (44%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4180 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4236
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4237 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4289
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4290 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4338
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
TG P V G+ +++ GG L E++G PT
Sbjct: 4339 KATGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4380
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4381 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4436
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4437 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4470
Score = 98.7 bits (235), Expect = 3e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3074 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3131
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3132 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3184
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3185 AWLKNYKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3242
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3243 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3280
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3281 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3339
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3340 TPTIRGNK----DEAEK-LMTYVDTSINIECRXTGTPPPQ 3374
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 157/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPKEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECNAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 94.3 bits (224), Expect = 7e-18
Identities = 95/366 (25%), Positives = 148/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E+ L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEEGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVSNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPKEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 93.9 bits (223), Expect = 9e-18
Identities = 92/368 (25%), Positives = 154/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2585 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2642
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2643 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2700
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2701 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2757
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2758 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2804
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2805 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2861
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P ++G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2862 YDVRVLVPPIIEGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2916
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2917 DDHHKFLS 2924
Score = 93.9 bits (223), Expect = 9e-18
Identities = 81/299 (27%), Positives = 120/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3253 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3310
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M
Sbjct: 3311 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTY 3356
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3357 VDTSIN------IECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3408
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3409 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3461
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3462 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3517
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3720 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3776
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3777 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3813
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3814 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3873
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3874 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3928
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3929 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3983
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3984 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4021
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4022 WQKEGINV 4029
Score = 93.5 bits (222), Expect = 1e-17
Identities = 87/365 (23%), Positives = 147/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L +G + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTF--TRSIRDTFHLAENE 2710
+ + P D+ EY C NE G NLKV+ +PP + + L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVSNVSVLLNQL 1377
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPKEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + +T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECKTRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2490 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2546
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2547 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2588
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2589 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2646
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2647 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2706
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2707 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2753
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPEGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 91.1 bits (216), Expect = 6e-17
Identities = 101/366 (27%), Positives = 143/366 (39%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4091 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4146
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4147 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4187
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4188 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4241
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4242 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4294
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG +G V V
Sbjct: 4295 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYV--- 4346
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4347 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4387
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4388 GVDIEI 4393
Score = 89.4 bits (212), Expect = 2e-16
Identities = 72/279 (25%), Positives = 116/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + + + ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKD--NCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSTQISDTGRYTCVAVNAAG 2090
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3931 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3990
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3991 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4047
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4048 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4084
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4085 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4141
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4142 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4194
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4195 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4247
Score = 87.8 bits (208), Expect = 6e-16
Identities = 93/372 (25%), Positives = 145/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2879 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2935
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2936 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2982
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2983 ---------ISLTCEVSGFPPPDLSWLKNXQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3031
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3032 GEYTCIAINXAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3085
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3086 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3142
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3143 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3181
Query: 3413 PDVYWLRDFLKV 3424
P + WL+++ ++
Sbjct: 3182 PTIAWLKNYKRI 3193
Score = 87.4 bits (207), Expect = 8e-16
Identities = 88/342 (25%), Positives = 137/342 (40%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T + +E+G L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTGREPGISI-LEEGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------SNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3811 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3869
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3870 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3906
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3907 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3964
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3965 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4015
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4016 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4070
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4071 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4109
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4110 DITWHKD 4116
Score = 86.6 bits (205), Expect = 1e-15
Identities = 90/363 (24%), Positives = 137/363 (37%), Gaps = 53/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK T++ + + + D Q T+ +
Sbjct: 2170 GRYTCEATNVAGK----------TEKKNYNVNIWVPPNIGGS---DELTQLTV------I 2210
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ + L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2211 EGNL-ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2269
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2270 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2323
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2324 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2380
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P W
Sbjct: 2381 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSTTW 2421
Query: 3418 LRD 3420
+D
Sbjct: 2422 FKD 2424
Score = 85.8 bits (203), Expect = 2e-15
Identities = 87/365 (23%), Positives = 148/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P W K+G V + R+ S L +
Sbjct: 2394 PENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2449
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2450 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2488
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2489 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2546
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2547 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2604
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2605 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2661
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2662 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2707
Query: 3416 YWLRD 3420
W +D
Sbjct: 2708 SWYKD 2712
Score = 85.0 bits (201), Expect = 4e-15
Identities = 89/342 (26%), Positives = 128/342 (37%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D L S MT GQI + + + DAG+Y C A N G ++V +
Sbjct: 1954 WYKDNCLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.0 bits (201), Expect = 4e-15
Identities = 91/367 (24%), Positives = 142/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2206 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2263
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2264 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2304
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2305 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2361
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2362 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2415
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2416 LPSTTWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2470
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2471 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2510
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2511 EITWHKD 2517
Score = 84.2 bits (199), Expect = 7e-15
Identities = 92/352 (26%), Positives = 141/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPKEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CKTRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ G P+ + WL++G V N +E G L + E + G Y C A S
Sbjct: 1662 ECNAAGNPSPILTWLKDG---VPVKANDNFRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 84.2 bits (199), Expect = 7e-15
Identities = 80/304 (26%), Positives = 121/304 (39%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2300 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2356
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2357 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2396
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P +W+KDG V + L + T ++D G
Sbjct: 2397 ISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2454
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2455 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2507
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2508 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2564
Query: 3355 KVEV 3358
+ V
Sbjct: 2565 SLNV 2568
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3447 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3504
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3505 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3559
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3560 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3616
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3617 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3653
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3654 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3710
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3711 NVPPNIKGGPQSLV 3724
Score = 81.8 bits (193), Expect = 4e-14
Identities = 98/417 (23%), Positives = 153/417 (36%), Gaps = 64/417 (15%)
Query: 3015 QGEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
+GEE + T N G+ + Q + + + GD P ++ +LAGE L C
Sbjct: 1042 EGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQDKPVEISVLAGEEVTLPC 1101
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1102 EVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGN 1158
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ +L V PP+ + +VQ V + C
Sbjct: 1159 VTQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCH 3252
G+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETE 1253
Query: 3253 CGLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V + P LEP Y + + P + W +G
Sbjct: 1254 ITLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRE 1306
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
L I L+ +G + L +A+VT D G Y C A NE G ++V
Sbjct: 1307 LTGREPGISILE-EGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV--------- 1355
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ + S + + + + + CEV G P P + W +D ++V
Sbjct: 1356 HVPPVIKDKE-QVSNVSVLLNQLTN----------LFCEVEGTPSPIIMWYKDNVQV 1401
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 57/362 (15%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--STQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE-----KKNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2229
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2230 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2286
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2287 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2328
Query: 3419 RD 3420
+D
Sbjct: 2329 KD 2330
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 87/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4080 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4136
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4137 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4188
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + Y A+ L ++N EDSG YTC A N+
Sbjct: 4189 LPCVADGIPTPAINWKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4245
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4246 AGED--THTVSLT 4256
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3886 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3945
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3946 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3996
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3997 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4053
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4054 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4088
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4089 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4144
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4145 GHYTCMAANVAGSSSTSTKLTVHVP 4169
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3915 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3971
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3972 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4008
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4009 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4066
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4067 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4119
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4120 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4166
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4167 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4206
Score = 77.8 bits (183), Expect = 6e-13
Identities = 77/318 (24%), Positives = 135/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD+ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNCLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSTQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 77.4 bits (182), Expect = 9e-13
Identities = 87/370 (23%), Positives = 144/370 (38%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2204 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2263
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2264 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2316
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2317 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2366
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2367 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2411
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2412 SGIPLPSTTWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2468
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2469 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2521
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2522 QEDEAHHIIS 2531
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 142/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PKEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECKTRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECNAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--FRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 76.6 bits (180), Expect = 1e-12
Identities = 84/343 (24%), Positives = 134/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2976 TVVVNNFISLTCEVSGFPPPDLSWLKNXQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3033
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N G +L VY PS + ++R+ + LEC P
Sbjct: 3034 YTCIAINXAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3088
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3089 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3145
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3146 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3181
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3182 PTIAWLKNYKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3240
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3241 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3277
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4139 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4191
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4192 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4248
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4249 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4285
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4286 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4340
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4341 -TGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4394
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4395 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4441
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4442 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4476
Score = 74.9 bits (176), Expect = 5e-12
Identities = 83/383 (21%), Positives = 156/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + + L +P
Sbjct: 1042 EGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDLRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.1 bits (174), Expect = 8e-12
Identities = 81/344 (23%), Positives = 141/344 (40%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2884 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2940
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2941 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2993
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+ + I + + G L I D G YTC A
Sbjct: 2994 PPDLSWLKNXQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3038
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3039 INXAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3089
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3090 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3146
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3147 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3182
Score = 73.7 bits (173), Expect = 1e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2682 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2738
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2739 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2787
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2788 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2842
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2843 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECL 2896
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2897 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2953
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2954 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2992
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2993 PPPDLSWLKNXQPIKL 3008
Score = 73.3 bits (172), Expect = 1e-11
Identities = 80/343 (23%), Positives = 132/343 (38%), Gaps = 42/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
+ VE + V LTC P+ TW+++G V L N ++ ++ G L ++ D+
Sbjct: 2398 SVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVR----ILSGGRMLRLMQTTMEDA 2453
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT--RSIRDTFHLAENELVLECRIRG 2719
+Y+C V N G L V +PP ++ D + + L C + G
Sbjct: 2454 GQYTCVVRNAAGEERKIFGLSVL-------VPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2506
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P+P+ITW KD + + D +A ++ G L I N +G YTC A + +
Sbjct: 2507 NPVPEITWHKDGQPLQED---EAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRS 2563
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+N VSP + GN D V L E
Sbjct: 2564 FSLNVF-----VSPTIAGVGSD--------------GNP-EDVTVILNSPTSLVCEAYSY 2603
Query: 2840 -PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + W ++G + E RN R+ G TL + + E +G Y+C A + G + +
Sbjct: 2604 PPATITWFKDGTPL-ESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHY 2660
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEP 2941
+ V P ++ G K++ I V + + P
Sbjct: 2661 EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP 2703
Score = 72.9 bits (171), Expect = 2e-11
Identities = 80/360 (22%), Positives = 144/360 (40%), Gaps = 46/360 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSTQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD-MNA 2898
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKKNY 2188
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 NVNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2241
Score = 72.1 bits (169), Expect = 3e-11
Identities = 77/345 (22%), Positives = 131/345 (37%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3255 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3314
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P + + +ECR G
Sbjct: 3315 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTYVDTSINIECRXTGT 3370
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3371 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3426
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3427 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3464
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3465 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3521
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3522 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3560
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3445 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3501
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3502 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3540
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3541 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3598
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3599 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3652
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3653 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3701
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3702 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3747
Query: 3418 LRD 3420
+D
Sbjct: 3748 RKD 3750
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3631 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3688
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3689 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3741
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3742 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3794
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3960 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4019
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4020 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4077
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4078 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4128
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4129 LSSGSLQIAF--VQPGDAGHYTCMAAN 4153
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3538 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3594
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3595 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3639
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3640 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3691
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3692 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3744
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3745 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3801
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3802 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3848
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4365 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4420
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4421 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4473
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4474 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4514
Score = 67.7 bits (158), Expect = 7e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2975 LTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3031
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3032 GEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3072
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3073 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3130
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3131 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3182
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3183 TIAWLKNYKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3241
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3242 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3281
Query: 3418 LRD 3420
L+D
Sbjct: 3282 LKD 3284
Score = 66.9 bits (156), Expect = 1e-09
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 66.9 bits (156), Expect = 1e-09
Identities = 77/338 (22%), Positives = 134/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2796 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVL--ILPGGRVLQIPRAKVEDAGRYTCVAVN 2853
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL-ECRIRGQPLPKITWFK 2729
E G S +++V PI + + + N+ L EC G P P+ +W K
Sbjct: 2854 EAGEDSLQYDVRVL----VPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2909
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2910 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2961
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2962 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3002
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3003 XQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVYVP--- 3056
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3057 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3091
Score = 65.7 bits (153), Expect = 3e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPEGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 65.7 bits (153), Expect = 3e-09
Identities = 56/193 (29%), Positives = 82/193 (42%), Gaps = 30/193 (15%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G A L C VKG P P + W + G ++E + R+ NG L I +D G Y+C
Sbjct: 4365 GGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIRQLGNG---SLAIYGTVNEDAGDYTC 4420
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
ATN G VV ERS + PP T+ + + A
Sbjct: 4421 VATNEAG---------VV--------------ERSMSLTLQSPPIITLEPVETVINAGGK 4457
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ L CQ G P P ++W + G + +D R N + ++L IA +D +E ARN
Sbjct: 4458 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARN 4514
Query: 3245 NSGAVSCHCGLVV 3257
G+V ++V
Sbjct: 4515 LMGSVLVRVPVIV 4527
Score = 65.3 bits (152), Expect = 4e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3070 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3126
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3127 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3164
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3165 TISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3224
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3225 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3278
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3279 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3336
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3337 -------------VYVTPTIRGNKD-----EAEKLMTYVDTSINIECRXTGTPPPQINWL 3378
Query: 3419 RDFL 3422
++ L
Sbjct: 3379 KNGL 3382
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.5 bits (145), Expect = 3e-08
Identities = 77/345 (22%), Positives = 138/345 (40%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C+ + P +TW ++GV + +R + G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECNAAGNPSPILTWLKDGVPVKANDNFR--IEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2461 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2520
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2521 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2578
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2579 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2633
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2634 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2683
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2684 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2733
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2734 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2766
Score = 60.5 bits (140), Expect = 1e-07
Identities = 83/366 (22%), Positives = 135/366 (36%), Gaps = 64/366 (17%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECKTRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-FHTLEIAPTNLDDG 3235
++V + + L C G+P P ++W KDG V K + ++ E LEI D
Sbjct: 1651 KQVVIAHSLTLECNAAGNPSPILTWLKDGVPV---KANDNFRIEAGGKKLEIMSAQEIDR 1707
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAY 3294
G Y A + +G + + V P G E Y + + L + V
Sbjct: 1708 GQYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGS 1761
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P + W +DG +L R L ++ +A A V+ + G+Y C A+N G
Sbjct: 1762 PPPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEF 1818
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+V V +PP + S + S+ + KP V ++C G P P
Sbjct: 1819 EVTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPS 1857
Query: 3415 VYWLRD 3420
+ WL+D
Sbjct: 1858 ITWLKD 1863
Score = 58.0 bits (134), Expect = 6e-07
Identities = 48/179 (26%), Positives = 71/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4261 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4316
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + + V PP F + +
Sbjct: 4317 ERVSKEDSGTYVCTAENSVGFVKATGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4369
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4370 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4424
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3812 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3868
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3869 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3921
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3922 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3973
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3733 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3789
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3790 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3842
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3843 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3896
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3897 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3936
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3937 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3993
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3994 QPSELHVILNNP 4005
Score = 54.8 bits (126), Expect = 5e-06
Identities = 51/189 (26%), Positives = 74/189 (39%), Gaps = 12/189 (6%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQIT 2779
N T+ T
Sbjct: 964 NVAGTNNKT 972
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3629 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3685
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3686 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3729
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3730 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3780
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3781 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3833
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3834 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3884
Score = 40.3 bits (90), Expect = 0.12
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P + + P + I AG L C G+P P + W + GH + + R+ N L
Sbjct: 4440 PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWD-DRVNVLSNN---SL 4495
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I D +D + C A N G S R+ V+
Sbjct: 4496 YIADAQKEDTSEFECVARNLMG--SVLVRVPVI 4526
Score = 35.9 bits (79), Expect = 2.6
Identities = 68/334 (20%), Positives = 127/334 (38%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ ++L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVSLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4430 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4488
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4489 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4519
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 99.5 bits (237), Expect = 2e-19
Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L C + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 3130
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 3131 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 3183
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 3241
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 3242 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 3280 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 3339 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 3373
Score = 97.5 bits (232), Expect = 7e-19
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 4235
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 4236 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 4337
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ +++ GG L E++G PT
Sbjct: 4338 KAIGFVYVKEPPVFK------------------GDYPSNWIEPLGGNAILNCEVKGDPTP 4379
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 4380 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 4436 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 4469
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 1370 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGK--ILKLFRATPEDA 1426
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 1470
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 1471 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 1523
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 1524 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 1578 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 1634
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 1635 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 1676 LKDGVPVK 1683
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 3309
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 3310 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 3355
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 3356 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 3407
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 3460
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 3461 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 95.5 bits (227), Expect = 3e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 1268 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 1324
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 1325 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 1377
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGKI-LKLFRATPEDAGRYSCKAI 1434
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 1435 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 1471
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 1529
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 1582
Query: 2950 IPGEP 2954
G+P
Sbjct: 1583 KDGQP 1587
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 3775
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 3776 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 3812
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 3813 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 3872
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 3873 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 3927
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 3928 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 3983 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 4020
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 4021 WQKEGINV 4028
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 1233
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 1281
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 1282 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 1334
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 1387
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 1388 PSPIIMWYKDNVQVTES-STIQTVN-NGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 1444
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 1445 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 1484
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 1485 IHWFKD 1490
Score = 92.7 bits (220), Expect = 2e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 1046
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 1091
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 1149
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 1150 CVATNIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 1202
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 1203 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 1251
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 1252 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302
Query: 3420 D 3420
+
Sbjct: 1303 N 1303
Score = 92.7 bits (220), Expect = 2e-17
Identities = 92/368 (25%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + S L C S T+TW+++G L++ R ++ G TL++LNA ++
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR--ILPGGRTLQILNAQEDNA 2641
Query: 2662 AEYSCTVENENGAISTSANLKVY--PSFEASPI-PPTFTRSIRDTFHLAENELVLECRIR 2718
YSC NE G + +KVY P + P S ++ N L LEC
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL--SPKEVKIKVNNTLTLECEAY 2699
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
P ++W+KD + + SD +A L I D+G YTC A N D++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVN---IAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL 2756
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
VN QV P+ +K L++ R G V I L E
Sbjct: 2757 DFDVNI-----QVPPSF---QKLWEIGNMLDTGRN--GEA---KDVIINNPISLYCETNA 2803
Query: 2839 C-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
P + W ++G +T + +V + G L + ++G YTC A + G +
Sbjct: 2804 APPPTLTWYKDGHPLTS---SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+ V+ P + G + + PE ++ + V + I + G P P+ ++ G+P +
Sbjct: 2861 YDVRVLVPPIIKGANSDL---PE-EVTVLVNKSALIECLSSGSPAPRNSWQK-DGQPLLE 2915
Query: 2958 DGGNNWVS 2965
D + ++S
Sbjct: 2916 DDHHKFLS 2923
Score = 92.3 bits (219), Expect = 3e-17
Identities = 78/290 (26%), Positives = 118/290 (40%), Gaps = 27/290 (9%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+K+ ++ LTC V G PVP + W K+G ++E+ F L I ++ +
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF---LQITNVQVPHT 2545
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+C A++ G S L V T+ A V D P+ D V
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTI------------AGVGSDGNPE------DVTV 2587
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
P L C+ PP ++W+KDG + + RN TL+I D+ G Y
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPL--ESNRNIRILPGGRTLQILNAQEDNAGRYS 2645
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N +G + H + V + GL P K+ + L + A PS
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
++WY+DG L+ + + +G L + D G YTC ASN G
Sbjct: 2706 LSWYKDGQPLKSDDH--VNIAANGH-TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 91.5 bits (217), Expect = 5e-17
Identities = 94/353 (26%), Positives = 148/353 (41%), Gaps = 51/353 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRN--GVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T G R LTC +IS+ D +TW RN V L + R L + ++LE+ + +D+
Sbjct: 530 TVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLAN--LSLELKSVKFNDA 586
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
EY C V +E G+ + S L V PP T ++ +E+ + C G P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQE-------PPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKI W +D I RY+ +DG L I N P+D+G Y C A NS TD+
Sbjct: 640 KPKIAWTVNDMFIVGSHRYR--MTSDGT--LFIKNAAPKDAGIYGCLASNSAGTDK---- 691
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N T R + +V + +A L D V T G+ P
Sbjct: 692 QNSTLRYIEAPKLMVVQSELLVA--------------LGDITVMECKTSGIP------PP 731
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+V+W + E+ + + ++ L L + + + ++G YTC A + G +
Sbjct: 732 QVKWF---KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V G P V + P D+ + +G ++ + QG P+P R+ P
Sbjct: 789 V-------GSPPVFIQEP-ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 1903
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1942
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1943 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 2000
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 2001 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 2053
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 2054 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 2090
Score = 91.1 bits (216), Expect = 6e-17
Identities = 89/363 (24%), Positives = 137/363 (37%), Gaps = 54/363 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 2113 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 2169
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
GRY+CEATN GK + + + +D + + +EG+
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD---ELTQLTVIEGNL------------- 2213
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C+ G PPP + W K G V+ D L+I+ D +Y
Sbjct: 2214 -----ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKL-HEGDELRISAVVEAYPSV 3297
A N +G L V Y+ P G P + G + + V+ P
Sbjct: 2269 CVASNVAGTAKKEYNLQV------YIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
VTW +DG L + + + LD +G I L L + D G Y C A N G +
Sbjct: 2323 TVTWMKDGHPLIKA-KGVEILD-EGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V PP +I R P + E ++V + CE G P P + W
Sbjct: 2380 V---------HAPPSIIGNH----------RSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 3418 LRD 3420
+D
Sbjct: 2421 FKD 2423
Score = 89.8 bits (213), Expect = 1e-16
Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 64/366 (17%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAFVQPGDAGH 4145
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 4186
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 4187 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 4240
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 4241 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 4294 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 4345
Query: 3362 DQTSEPRIPPVVISPDVPYS-KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ PP V D P + EP+ G I+ CEV GDP P + W R
Sbjct: 4346 ------KEPP-VFKGDYPSNWIEPL------------GGNAILNCEVKGDPTPTIQWNRK 4386
Query: 3421 FLKVRI 3426
+ + I
Sbjct: 4387 GVDIEI 4392
Score = 88.6 bits (210), Expect = 3e-16
Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 3930 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 4046
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 4083
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+IA
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQP 4140
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 4141 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 4193
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 4194 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 4246
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 1147
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 1297
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 1298 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 1354
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 1355 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 1390
Score = 87.0 bits (206), Expect = 1e-15
Identities = 87/365 (23%), Positives = 149/365 (40%), Gaps = 47/365 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDIN 3115
P + ++ + +LTC G P+P + W K+G V + R+ S L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR----MLRLMQTT 2448
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
++D G+Y+C N G+ L+V+ + G+ L
Sbjct: 2449 MEDAGQYTCVVRNAAGEERKIFGLSVLVP---------------PHIVGENT------LE 2487
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D +V+ V LTC+V G+P P+++W+KDG+ + D+ + +F L+I +
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y A + +G S L V + +A G + + +YP
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVF--VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYP 2603
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW++DG L S R I L G L + +AG Y+C A+NE G +
Sbjct: 2604 PATITWFKDGTPLE-SNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V+V IPP++ D+ P P+ + + +T+ +ECE P +
Sbjct: 2661 VKVY---------IPPIINKGDL---WGPGL--SPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 3416 YWLRD 3420
W +D
Sbjct: 2707 SWYKD 2711
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 3868
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 3869 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 3905
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 3906 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 3963
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 3964 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 4014
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 4069
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 4070 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 4108
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 4109 DITWHKD 4115
Score = 86.2 bits (204), Expect = 2e-15
Identities = 91/367 (24%), Positives = 143/367 (38%), Gaps = 60/367 (16%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINID 3117
QL ++ G +L C G P P ++W K G V + GR+ G ++I + +
Sbjct: 2205 QLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS-- 2262
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D YSC A+N G A L V T+ + G +P +
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNS-------------GSHPTEII------ 2303
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C+V G PPP V+W KDG ++ K + ++ H L++ ++ D G
Sbjct: 2304 -VTRGKSISLECEVQGIPPPTVTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA--YP 3295
Y A N +G L V + P + ++ +S EA P
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV------HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 3296 SVGVTWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
+TW++DG V L S R + G L L T DAG YTC N G
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ +PP ++ + + +E +V + CEV G+P P
Sbjct: 2470 FGLSVL---------VPPHIVGENT-----------LEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 3414 DVYWLRD 3420
++ W +D
Sbjct: 2510 EITWHKD 2516
Score = 86.2 bits (204), Expect = 2e-15
Identities = 93/372 (25%), Positives = 144/372 (38%), Gaps = 60/372 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +L ++A + C G P P W K+G + E+ +F L I +
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHH---KFLSNGRILQILNTQ 2934
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
I D GRY C A NT G A Y L V +V K E V ++
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP----KSENLTVVVNNF--------- 2981
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
+ LTC+V G PPP +SW K+ + + + N TL+I + DG
Sbjct: 2982 ---------ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDG 3030
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVE 3292
G Y A N +G L V YV P + + + EG + +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
A P +TWY++G + S + + DGQ+ L + D G Y C A N GR
Sbjct: 3085 AVPPPVITWYKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDK 3141
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
+ + V +PP + P+ E + + V + C+ G P
Sbjct: 3142 NFHLNVY---------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPP 3180
Query: 3413 PDVYWLRDFLKV 3424
P + WL++ ++
Sbjct: 3181 PTIAWLKNHKRI 3192
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 1568
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 1569 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 1625
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 1626 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 1661
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 1662 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 1719 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 1764
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G ++E G NG L I + + G
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILLNGRK--LVIAQAQVSNTGL 1802
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G ++ EV PP RV
Sbjct: 1803 YRCMAANTAGD-----------------------HKKEFEVTVHVPPTIKSSGLSERVVV 1839
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 1898
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1953
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1954 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 2052
Score = 85.4 bits (202), Expect = 3e-15
Identities = 80/304 (26%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ + G++ +L C V+G P P V WMK+GH + + G + L +K+I++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHV 2355
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C A N G L+V ++ + RS E +
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSI------IGNHRSPE--------------N 2395
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V V LTC+ G P P ++W+KDG V + L + T ++D G
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMEDAG 2453
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL--YKLHEGDELRISAVVEAY 3294
Y RN +G GL V + P G L K+ E + ++ V
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSV-------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P +TW++DG L+ + G L + V G YTC AS+ G S S
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 3355 KVEV 3358
+ V
Sbjct: 2564 SLNV 2567
Score = 83.4 bits (197), Expect = 1e-14
Identities = 100/416 (24%), Positives = 151/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C ATN G
Sbjct: 1103 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 1160 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 1254
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 1255 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 1307
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 1308 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 1356
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 1357 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 3503
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 3504 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 3558
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 3559 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 3616 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 3652
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 3653 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 3710 NVPPNIKGGPQSLV 3723
Score = 81.8 bits (193), Expect = 4e-14
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 58/362 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 2080
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G+ ++R ++ PP ++ V
Sbjct: 2081 YTCVAVNAAGE-----------------------KQRDIDLRVYVPPNIMGEEQNVSVLI 2117
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH--EGDELRISAVVEAYPSVGV 3299
A N +G + + +V P G + L +L EG+ + + P +
Sbjct: 2176 ATNVAGKTE------KNYNVNIWVPPNI-GGSDELTQLTVIEGNLISLLCESSGIPPPNL 2228
Query: 3300 TWYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W + G L S + L Q+++++A + DA +Y+C ASN G A ++
Sbjct: 2229 IWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQ- 2285
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V I P + S P G ++ +ECEV G P P V W+
Sbjct: 2286 -------------VYIRPTITNSGS-----HPTEIIVTRGKSISLECEVQGIPPPTVTWM 2327
Query: 3419 RD 3420
+D
Sbjct: 2328 KD 2329
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 128/308 (41%), Gaps = 37/308 (12%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ G + L C V PTVTW ++G L K K + L +G I L++ N SD
Sbjct: 2300 TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSD 2357
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C N G +L V+ A P RS + + +N + L C G
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
PLP ITWFKD + + + G L + T ED+G YTC N+ ++
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVR---ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER--- 2467
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
G V P++V N L D +V ++ L E+ G P
Sbjct: 2468 --KIFGLSVLVPPHIVGE------------------NTLEDVKVKEKQSVTLTCEVTGNP 2507
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W ++G+ + E A + G + L +++V +G YTC A S G+ + +
Sbjct: 2508 VPEITWHKDGQPLQE--DEAHHIISGGRF-LQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564
Query: 2900 ITV-VQPS 2906
+ V V P+
Sbjct: 2565 LNVFVSPT 2572
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 4135
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 4187
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 4188 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 4245 AGED--THTVSLT 4255
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 1888
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 1889 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1941
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1942 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1999 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 2033
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 2092 KQRDIDLRVYVPPNIMGE 2109
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 3885 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 3944
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 3945 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 3995
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 4052
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 4087
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 4088 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQIAFVQPGDA 4143
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 79.0 bits (186), Expect = 3e-13
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 3970
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 3971 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 4007
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 4065
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 4066 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 4118
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++A V DAG YTC A+N G +STS K+ V
Sbjct: 4119 IVESIRQRVLS---SGSLQIAF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 4165
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 4166 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 4205
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 1517
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 1558
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 1559 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 1614
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 1667
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 1668 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 1725 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 1764
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 1765 TIMWLKD 1771
Score = 78.6 bits (185), Expect = 4e-13
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 46/370 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
LT T +EG+ + L C P + W + G + R +++ G L++ A S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHLAENELVLECR 2716
D+A YSC N G NL+VY I PT T S + + LEC
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVY-------IRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
++G P P +TW KD + + + + D L + N D+G Y C A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLI---KAKGVEILDEGHILQLKNIHVSDTGRYVCVA------- 2365
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
VN G + V A + I R P + V ++ L E
Sbjct: 2366 -----VNVAGMTDKKYDLSVHAPPSIIGNH----RSPE------NISVVEKNSVSLTCEA 2410
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W ++G V+ + + R+ G L L T ++G YTC +A G
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
++V+ P + G+ + +D+ + + + ++ G P P+ + G+P
Sbjct: 2468 KIFGLSVLVPPHIVGENTL------EDVKVKEKQSVTLTCEVTGNPVPEITWHK-DGQPL 2520
Query: 2956 VVDGGNNWVS 2965
D ++ +S
Sbjct: 2521 QEDEAHHIIS 2530
Score = 77.8 bits (183), Expect = 6e-13
Identities = 84/343 (24%), Positives = 135/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 3032
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LEC P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLECESNAVP 3087
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 3088 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 3145 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 3180
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 3181 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 3240 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 3276
Score = 76.6 bits (180), Expect = 1e-12
Identities = 89/365 (24%), Positives = 139/365 (38%), Gaps = 62/365 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
+P + + GE A LTC + + W +N +V E R+ + N L +K +
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSV 581
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+D G Y C ++ G ++ L TV E PP+ T+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFL------TVQE-----------------PPKVTVMP 618
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+++ V + C G P PK++W + +V R D AP D
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAP---KD 675
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G+Y A N++G + +R AP+ L + GD +
Sbjct: 676 AGIYGCLASNSAGTDK------QNSTLRYIEAPKLMVVQSELL-VALGDITVMECKTSGI 728
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W++ + LRPS + +D + L + DAG YTC A NE GRA +G
Sbjct: 729 PPPQVKWFKGDLELRPS--TFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRA--TG 783
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K+ + DV P+FI++P G V + C V G P+P
Sbjct: 784 KITL------------------DV--GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 3415 VYWLR 3419
+ W R
Sbjct: 824 IKWRR 828
Score = 76.6 bits (180), Expect = 1e-12
Identities = 80/359 (22%), Positives = 144/359 (40%), Gaps = 45/359 (12%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
+ + T + + V+L C + P +TWY++ LL L G I +++ +A S
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQI-IDIESAQIS 1984
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ Y C N GA +L+V+ + P+ + S + N + LEC RG
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH-------VAPSISGSNNMVAVVVNNPVRLECEARG 2037
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P +TW KD + S + G LA+ + D+G YTC A N+ Q
Sbjct: 2038 IPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-- 2093
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
V PN++ E+ NV +++ + Q +
Sbjct: 2094 ---RDIDLRVYVPPNIMGEEQ----------------NV--SVLISQAVELLCQSDAIPP 2132
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
PT + WL++G + + + + + L + D ++G YTC A + G + N
Sbjct: 2133 PT-LTWLKDGH---PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
+ + P ++ G + + + G I++ + G P P + ++ G P + D
Sbjct: 2189 VNIWVPPNIGGSDEL------TQLTVIEGNLISLLCESSGIPPPNLIWKK-KGSPVLTD 2240
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 4138 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 4190
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 4247
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 4248 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 4340 -IGFVYVKEPPVFKGDYPSNWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 4394 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 4440
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 4441 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 4475
Score = 75.8 bits (178), Expect = 3e-12
Identities = 83/383 (21%), Positives = 157/383 (40%), Gaps = 46/383 (12%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKL 2638
I + T++ P+ + +EG ++ L C++++ + P W +N +L
Sbjct: 876 IQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN- 934
Query: 2639 KYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR 2698
Y DG + +E + D EY+C N G + + ++ V+ + PT
Sbjct: 935 PYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQH 985
Query: 2699 SIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNP 2757
+ + + L C+ G P P + W K + I S ++ A ADG L + +P
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSP 1041
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGN 2817
E+SG Y C A N+ + R+ Q++ V + ++ L +P
Sbjct: 1042 GGEESGEYVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP---- 1086
Query: 2818 VLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVT 2876
+ V G + L E++ P + W +E + ++ + F+ G ++ +++
Sbjct: 1087 --VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETR 1141
Query: 2877 ETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFR 2936
++SG+Y C A + GNV + V P + P K + + VG+ ++I
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCN 1193
Query: 2937 TQGEPKPKAVPERIPGEPCVVDG 2959
QG P P + G +VDG
Sbjct: 1194 AQGTPLP-VITWSKGGSTMLVDG 1215
Score = 74.5 bits (175), Expect = 6e-12
Identities = 81/344 (23%), Positives = 142/344 (41%), Gaps = 49/344 (14%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
T + + C S P +W ++G LL++ + K L +G I L++LN +D
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--HHKFLSNGRI-LQILNTQITDIG 2939
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
Y C EN G+ NL V+ +PP+ + + N + L C + G P
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVH-------VPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ++W K+++ I + + G L I D G YTC A
Sbjct: 2993 PPDLSWLKNEQPIKLNTN---TLIVPGGRTLQIIRAKVSDGGEYTCIA------------ 3037
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+N G ES+ +K + S + H L+ V G ++ L+ E P
Sbjct: 3038 INQAG-ESK--------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V W + GR +TE + + + + + ++V++T G Y CRA + G D N +
Sbjct: 3089 PVITWYKNGRMITE-STHVEILADGQMLHIKKAEVSDT--GQYVCRAINVAGRDDKNFHL 3145
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILI-SVGEDINISFRTQGEPKP 2943
V P ++G PE+++++ ++ + ++ G P P
Sbjct: 3146 NVYVPPSIEG--------PEREVIVETISNPVTLTCDATGIPPP 3181
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 3369
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 3370 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 3425
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 3426 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 3463
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 3464 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 3520
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 3521 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 3559
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/376 (23%), Positives = 139/376 (36%), Gaps = 55/376 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++KI T L C P + W K+G ++ + + NG L IK+ I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD-DHVNIAANGHT--LQIKEAQI 2737
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D GRY+C A+N G+ + + + +WE L R+ E
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEA----------- 2786
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
+ V P+ L C+ +PPP ++WYKDG + + + L+I ++
Sbjct: 2787 ---KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR--VLQIPRAKVE 2841
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF---CCGLEPLYKLHEGDELRISAV 3290
D G Y A N +G S + +R V P L + I +
Sbjct: 2842 DAGRYTCVAVNEAGEDS------LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECL 2895
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
P+ +W +DG L +G+I L + D G Y C A N G A
Sbjct: 2896 SSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRI-LQILNTQITDIGRYVCVAENTAGSA 2952
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V +PP VI P K + + + + CEV G
Sbjct: 2953 KKYFNLNV---------HVPPSVIGP------------KSENLTVVVNNFISLTCEVSGF 2991
Query: 3411 PKPDVYWLRDFLKVRI 3426
P PD+ WL++ +++
Sbjct: 2992 PPPDLSWLKNEQPIKL 3007
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 3500
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 3539
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 3540 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 3597
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 3598 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 3652 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 3700
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 3701 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 3746
Query: 3418 LRD 3420
+D
Sbjct: 3747 RKD 3749
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 3687
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 3740
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 3741 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 4077 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 4127
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G ++A P D+G YTC A N
Sbjct: 4128 LSSGSLQIAF--VQPGDAGHYTCMAAN 4152
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 3593
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 3594 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 3639 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 3690
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 3691 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 3743
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 3744 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 3847
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 4419
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 4420 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 4473 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 4513
Score = 67.7 bits (158), Expect = 7e-10
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 56/381 (14%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGR 3097
S V + G + I P ++ G+ L C++ G P+P W+KN + +
Sbjct: 878 SETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-Y 936
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+T + +G L I+ + + D G Y+C A+N G + + V T+ L
Sbjct: 937 ITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL--- 990
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
+ +EG PV L C+ G+P P V W K GE + K+
Sbjct: 991 --STIEG------------------IPVTLPCKASGNPKPSVIWSKKGE--LISTSSAKF 1028
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL- 3276
+L + ++ G Y TA N +G L V R + +P+
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ G+E+ + V++ P +TW ++ + P L + + T D+
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDS 1145
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+Y C A+N G + + K+ V +PP + R P+ + +
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV---------HVPPKI-------------QRGPKHLKVQ 1183
Query: 3397 EGDTVIIECEVVGDPKPDVYW 3417
G V I C G P P + W
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITW 1204
Score = 67.3 bits (157), Expect = 9e-10
Identities = 81/363 (22%), Positives = 135/363 (37%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 3030
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 3071
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L C+ PPP ++WYK+G + D Q L I + D G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 3129
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEG---PEREVIVETI-----SNPVTLTCDATGIPPP 3181
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGS-KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 3241 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 3280
Query: 3418 LRD 3420
L+D
Sbjct: 3281 LKD 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 4339 AIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 4397
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 4398 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 4431
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 4432 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 4491
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 4492 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 1048
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 1049 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 1107
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A N
Sbjct: 1108 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVATN--------- 1154
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ NV A K + R P +V G + + +G P
Sbjct: 1155 ----------IAGNVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 1198
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 1257 HVQEPPTVE 1265
Score = 66.1 bits (154), Expect = 2e-09
Identities = 76/338 (22%), Positives = 133/338 (39%), Gaps = 44/338 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
+ L C ++ PT+TWY++G L + K ++ G L++ A D+ Y+C N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSI-RDTFHLAENELVLECRIRGQPLPKITWFK 2729
E G S +++V PI + + L ++EC G P P+ +W K
Sbjct: 2853 EAGEDSLQYDVRVL----VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQK 2908
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
D + + D ++ +L++G L I N D G Y C AEN+ + + +
Sbjct: 2909 DGQPLLEDDHHK--FLSNGRI-LQILNTQITDIGRYVCVAENTAGSAK-----KYFNLNV 2960
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLRE 2848
V P+V+ + + V I L E+ G P + WL+
Sbjct: 2961 HVPPSVIGPKSENLT-------------------VVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 2849 GRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
+ + N + G TL + ++ G YTC A + G ++TV P
Sbjct: 3002 EQPIK---LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--- 3055
Query: 2909 DGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
P++ E +++V E ++S + P V
Sbjct: 3056 ---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Score = 66.1 bits (154), Expect = 2e-09
Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L C P P + W KNG + E + +G L IK + D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 3125
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 3163
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 3164 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 3223
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 3335
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 3336 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 3419 RDFL 3422
++ L
Sbjct: 3378 KNGL 3381
Score = 62.9 bits (146), Expect = 2e-08
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 45/328 (13%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG-HEVEEEAG 3096
SS+ V L P V ++P G ++ CS G P P + W N V
Sbjct: 599 SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRY 658
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
RMTS D L IK+ D G Y C A+N+ G + L + EA KL
Sbjct: 659 RMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI------EA-PKLMV 706
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK 3216
+S + + L D V + C+ G PPP+V W+K E+ R +
Sbjct: 707 VQS---------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLEL----RPST 746
Query: 3217 YQ--DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
+ D L+I T D G Y A N +G + + +D G P F E
Sbjct: 747 FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK--ITLDVG----SPPVFI--QE 798
Query: 3275 PL-YKLHEGDELRISAVVEAYPSVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
P + G + + V+ YP + W R D + + ++ ++ + L + +
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIG 3360
D G Y C A N+ G+ + V V G
Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 62.5 bits (145), Expect = 3e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 62/367 (16%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++ +L + G+ + C G P P V W K E+ + G L I++
Sbjct: 706 VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL---LKIQET 762
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G Y+C A N G+A+ L V + PP F
Sbjct: 763 QDLDAGDYTCVAINEAGRATGKITLDVGS-----------------------PPVFIQEP 799
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL-- 3232
D ++ V L C V G P P + W + ++ + + Q T + NL
Sbjct: 800 ADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWA 859
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKLHEGDELRISAVV 3291
D G Y A N G + + V VAP G+ P + + EG +L + +
Sbjct: 860 SDKGTYICEAENQFGKIQSETTVTV----TGLVAP--LIGISPSVANVIEGQQLTLPCTL 913
Query: 3292 EA-YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
A P W ++ L + +T+ DG L + V +D G YTC ASN G
Sbjct: 914 LAGNPIPERRWIKNSAML--LQNPYITVRSDG--SLHIERVQLQDGGEYTCVASNVAG-- 967
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
T+ K + V + P + + ++ + EG V + C+ G+
Sbjct: 968 -TNNKTTSV-----------VVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGN 1007
Query: 3411 PKPDVYW 3417
PKP V W
Sbjct: 1008 PKPSVIW 1014
Score = 62.1 bits (144), Expect = 3e-08
Identities = 71/333 (21%), Positives = 133/333 (39%), Gaps = 31/333 (9%)
Query: 2577 RSVISEKRTLSRNSTRKP---VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
R+ E+R + S P V L D E V LTC V + P +TW+++G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L + ++ G L++ N + Y+C + G S S +L V+ S + +
Sbjct: 2520 LQEDEAHH--IISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ D + + L C P ITWFKD + S+ + + G L
Sbjct: 2578 S--DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIR---ILPGGRTLQ 2632
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N +++G Y+C A N + I H+ P ++ K + L +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEA-GEMIKHY-----EVKVYIPPII--NKGDLWGPGLSPK-- 2682
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+ ++ T+ L+ E P+ + W ++G+ + + V + +TL +
Sbjct: 2683 -------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKS---DDHVNIAANGHTLQI 2732
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
+ +++G YTC A + G +++ + + P
Sbjct: 2733 KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Score = 61.7 bits (143), Expect = 5e-08
Identities = 77/345 (22%), Positives = 137/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 1707
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 1708 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 1760
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + I D R L +G +L I ++G Y C A N+ +
Sbjct: 1761 SPPPTIMWLKDGQLI--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 1815
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
+E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 1816 -------KEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 1853
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 1912 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1950
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 1613
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 1614 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 1650
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 1651 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 1709 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 1763 PPTIMWLKDG-QLIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFE 1819
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 1820 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 1858
Query: 3416 YWLRD 3420
WL+D
Sbjct: 1859 TWLKD 1863
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 3811 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 3867
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 3920
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 3972
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 4315
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSNWIEPLGGNAI 4368
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 4423
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 3732 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 3788
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 3789 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 3841
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 3842 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 3895
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 3896 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 3935
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 3936 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 3992
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 3993 QPSELHVILNNP 4004
Score = 55.6 bits (128), Expect = 3e-06
Identities = 82/355 (23%), Positives = 130/355 (36%), Gaps = 43/355 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT--L 2651
PVF D + GS V L C V +PT+ W R + + + L T L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LN SD Y C EN+ G I + + V + P S + +L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV-----TGLVAPLIGISPSVANVIEGQQL 907
Query: 2712 VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P+P+ W K+ + + +DG L I+ +D G YTC A
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITV--RSDG--SLHIERVQLQDGGEYTCVAS 963
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T+ T T V P + H +L+ + G +
Sbjct: 964 NVAGTNNKT-----TSVVVHVLPTI-----------------QHGQQILSTIE---GIPV 998
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L + G P V W ++G ++ + LY ++ ESG Y C A +
Sbjct: 999 TLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTATN 1055
Query: 2890 AHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G +TV V+P + + +P +I + GE++ + + P P
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP-VEISVLAGEEVTLPCEVKSLPPP 1109
Score = 49.2 bits (112), Expect = 3e-04
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 12/213 (5%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
+ S ++K+ + P ++ G + C P V W++ + L
Sbjct: 684 SNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743
Query: 2636 NKLKYRKKLVDGLI-TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
++D L+ L++ D+ +Y+C NE G + L V PP
Sbjct: 744 PSTFL---IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-------PP 793
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLA 2753
F + D + + L C ++G P P I W + D + ++ L
Sbjct: 794 VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
I N D GTY C+AEN Q V TG
Sbjct: 854 ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 3684
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 3728
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 3729 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 3779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 3780 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 3832
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 3833 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 3883
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 4487
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 4488 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 35.5 bits (78), Expect = 3.4
Identities = 68/334 (20%), Positives = 126/334 (37%), Gaps = 50/334 (14%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
++ CSV S T+++ RNGV L +Y K+ + L++ SD Y C
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVD-QYLKE--SASVNLDIAKVTLSDEGFYECI---- 500
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
A+S++ + F+ S PP T E VL C I +TW ++D
Sbjct: 501 --AVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE-RAVLTCLIISAVDYNLTWQRND 557
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ + + LA+ L + + D+G Y C + + + F+ Q
Sbjct: 558 RDVRLAEPARIRTLAN--LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QE 610
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P V K QS G + + G P ++ W
Sbjct: 611 PPKVTVMPK----NQSFTG----------------GSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ +R G TL + + ++G+Y C A ++ G N+ + ++
Sbjct: 651 FIVGSHRYR--MTSDG--TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------ 700
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
P ++V + ++L+++G+ + +T G P P+
Sbjct: 701 APKLMV--VQSELLVALGDITVMECKTSGIPPPQ 732
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 97.9 bits (233), Expect = 6e-19
Identities = 91/318 (28%), Positives = 134/318 (42%), Gaps = 44/318 (13%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQ 3101
G+ G+ +++ P + G T L C G PVP ++W + +G + +A R S
Sbjct: 218 GVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKS- 276
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
NG L I + +D G Y C A N+ GK +L
Sbjct: 277 -NGI---LEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQ----------------- 315
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
P + ++ D V V C+ G P P W K+GE ++ R++ Q EQ
Sbjct: 316 ------PNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLL---TRDRIQIEQ 366
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE 3281
TL I NL D G+Y+ A N G + + L V V P+F L L +
Sbjct: 367 -GTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSV-----IAVGPDFSRTLLKRVTLVK 420
Query: 3282 -GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
G E+ I +A P TW + L+ + R +T+ DG L + VT DAG YT
Sbjct: 421 VGGEVVIECKPKASPKPVYTWKKGRDILKENER--ITISEDGN--LRIINVTKSDAGSYT 476
Query: 3341 CTASNEVGRASTSGKVEV 3358
C A+N G AS++G + V
Sbjct: 477 CIATNHFGTASSTGNLVV 494
Score = 78.6 bits (185), Expect = 4e-13
Identities = 75/301 (24%), Positives = 125/301 (41%), Gaps = 42/301 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
+G+ VKL C + + PT+ W R +G + K + K +G+ LE+ N D+ Y
Sbjct: 239 KGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKS--NGI--LEIPNFQQEDAGLYE 294
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C EN G L Y P + + I D E + EC+ G+P P
Sbjct: 295 CVAENSRGKNVARGQLTFYAQ-------PNWIQKINDIHVAMEENVFWECKANGRPKPTY 347
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ + + + R Q + G + I N + D+G Y C AEN H V F+
Sbjct: 348 KWLKNGEPLLTRDRIQ---IEQGTLNITIVNLS--DAGMYQCLAENK-------HGVIFS 395
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEW 2845
E V +T + R +L V GG + ++ + + P V
Sbjct: 396 NAELSVIAVGPDFSRTLLKRVTL---------------VKVGGEVVIECKPKASPKPVYT 440
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
++GR + + N R+ + + L + +VT++++G YTC A + G + V P
Sbjct: 441 WKKGRDILK--ENERITISED-GNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDP 497
Query: 2906 S 2906
+
Sbjct: 498 T 498
Score = 64.1 bits (149), Expect = 8e-09
Identities = 89/347 (25%), Positives = 139/347 (40%), Gaps = 61/347 (17%)
Query: 3084 WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
W+ N + ++ R SQ G L I + D G Y+C TNT VT
Sbjct: 157 WIFNEYPSYQDNRRFVSQETGN---LYIAKVEKSDVGNYTCVVTNT------------VT 201
Query: 3144 DRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVSWY 3202
+ V L R+ V G+Y P+ ++ + A V+L C +G+P P + W
Sbjct: 202 NHKVLGPPTPLIL-RNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWR 260
Query: 3203 K-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI 3261
+ DG+ + RR+K LEI +D G+YE A N+ G V +
Sbjct: 261 RADGKPIARKARRHKSNG----ILEIPNFQQEDAGLYECVAENSRGKN------VARGQL 310
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
Y P + + ++ E + + P W ++G ++T DR
Sbjct: 311 TFYAQPNWIQKINDIHVAME-ENVFWECKANGRPKPTYKWLKNG-------EPLLTRDRI 362
Query: 3322 GQIE---LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
QIE L + V DAG+Y C A N+ G ++ ++ VI + PD
Sbjct: 363 -QIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI-------------AVGPD- 407
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL--RDFLK 3423
+S+ + R + + G V+IEC+ PKP W RD LK
Sbjct: 408 -FSRTLL----KRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILK 449
Score = 57.6 bits (133), Expect = 7e-07
Identities = 75/299 (25%), Positives = 123/299 (41%), Gaps = 46/299 (15%)
Query: 2651 LEVLNAVPSDSAEYSCTVEN---ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + SD Y+C V N + + L + P +T A
Sbjct: 179 LYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTA 238
Query: 2708 ENELV-LECRIRGQPLPKITWFK-DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ V LEC G P+P I W + D K I R + ++G+ L I N ED+G Y
Sbjct: 239 KGATVKLECFALGNPVPTIIWRRADGKPIARKARR---HKSNGI--LEIPNFQQEDAGLY 293
Query: 2766 TCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVA 2825
C AENS G+ NV + T A+ P++ + D VA
Sbjct: 294 ECVAENS------------RGK------NVARGQLTFYAQ-------PNWIQKINDIHVA 328
Query: 2826 RGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYT 2884
+ + + G P +WL+ G + R+ +EQG TL ++ V +++G+Y
Sbjct: 329 MEENVFWECKANGRPKPTYKWLKNGEPLLT---RDRIQIEQG--TLNITIVNLSDAGMYQ 383
Query: 2885 CRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
C A + HG + NA ++V+ D ++ ++ L+ VG ++ I + + PKP
Sbjct: 384 CLAENKHGVIFSNAELSVIAVGP-DFSRTLL----KRVTLVKVGGEVVIECKPKASPKP 437
Score = 55.2 bits (127), Expect = 4e-06
Identities = 70/294 (23%), Positives = 106/294 (36%), Gaps = 40/294 (13%)
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C G+P P W+KNG + Q L I +N+ D G Y C A N HG
Sbjct: 337 CKANGRPKPTYKWLKNGEPLLTRDRIQIEQGT-----LNITIVNLSDAGMYQCLAENKHG 391
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
+ A L+V+ + LKR +V G+ V + C+
Sbjct: 392 VIFSNAELSVIAVGPDFSRTL-LKRVTLVKVGGE-------------------VVIECKP 431
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
SP P +W K G +++ + R ++ L I D G Y A N+ G S
Sbjct: 432 KASPKPVYTW-KKGRDILKENERITISEDG--NLRIINVTKSDAGSYTCIATNHFGTASS 488
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV--TWYRDGVRL- 3308
LVV R V P + G+ + + V S+ + TW +G +
Sbjct: 489 TGNLVVKDPTRVMVPPS-------SMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 541
Query: 3309 --RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
R +D +L + + + AG Y C V R S + + V G
Sbjct: 542 FDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRG 595
Score = 52.0 bits (119), Expect = 4e-05
Identities = 71/250 (28%), Positives = 104/250 (41%), Gaps = 49/250 (19%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V+L C+V G+P P + W +G +V D + +Y + L P D G Y+ TA
Sbjct: 46 VKLNCEVKGNPKPHIRWKLNGTDV--DTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTAT 103
Query: 3244 NNSGA-VSCHCGL---VVDK---------GIRAYVAPEFCCGLEPLYKLHEGDELRISAV 3290
N+ G VS L +D +R CG P H G EL + +
Sbjct: 104 NSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPP----HSG-ELSYAWI 158
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
YPS Y+D +RR + G L +A V D G YTC +N V
Sbjct: 159 FNEYPS-----YQD------NRRFVS--QETG--NLYIAKVEKSDVGNYTCVVTNTV--- 200
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVG 3409
T+ K V+G P P ++ + V EP ++ P + +G TV +EC +G
Sbjct: 201 -TNHK--VLG------PPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALG 251
Query: 3410 DPKPDVYWLR 3419
+P P + W R
Sbjct: 252 NPVPTIIWRR 261
Score = 50.4 bits (115), Expect = 1e-04
Identities = 78/345 (22%), Positives = 130/345 (37%), Gaps = 49/345 (14%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E +VKL C V + P + W NG +D + +R +V+G + + N D+ Y C
Sbjct: 42 EEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKT-QDAGTYQC 100
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP-- 2723
T N G I S K+ ++ F R T + + +VL C G P
Sbjct: 101 TATNSFGTI-VSREAKLQFAY-----LDNFKTRTRSTVSVRRGQGMVLLC---GPPPHSG 151
Query: 2724 --KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
W ++ D R +++ L I D G YTC N+V
Sbjct: 152 ELSYAWIFNEYPSYQDNRR---FVSQETGNLYIAKVEKSDVGNYTCVVTNTV-------- 200
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
T + P + + + F + A+G T+ L+ G P
Sbjct: 201 ---TNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETV---PTAKGATVKLECFALGNPV 254
Query: 2842 -RVEWLR-EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG-NVDMNA 2898
+ W R +G+ + R AR G+ L + + + ++GLY C A ++ G NV
Sbjct: 255 PTIIWRRADGKPIA---RKARRHKSNGI--LEIPNFQQEDAGLYECVAENSRGKNVARGQ 309
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
QP+ + + DI +++ E++ + G PKP
Sbjct: 310 LTFYAQPNWI---------QKINDIHVAMEENVFWECKANGRPKP 345
Score = 45.2 bits (102), Expect = 0.004
Identities = 82/363 (22%), Positives = 130/363 (35%), Gaps = 70/363 (19%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN-IDDEGRYSCEATN 3128
L C VKG P P + W NG +V+ M +++ + L I + N D G Y C ATN
Sbjct: 48 LNCEVKGNPKPHIRWKLNGTDVDT---GMDFRYSVVEGSLLINNPNKTQDAGTYQCTATN 104
Query: 3129 THGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRL 3187
+ G +V+ R A+++ Y F R R V+ + L
Sbjct: 105 SFG--------TIVS--------------REAKLQFAYLDNFKTRTRSTVSVRRGQGMVL 142
Query: 3188 TCQVIGSPPP-----KVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
C PPP +W + D RR + ++ L IA D G Y
Sbjct: 143 LC----GPPPHSGELSYAWIFNEYPSYQDNRR--FVSQETGNLYIAKVEKSDVGNYTCVV 196
Query: 3243 RN---NSGAVSCHCGLVV-DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
N N + L++ + G+ P+ +G +++ P
Sbjct: 197 TNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPT 256
Query: 3299 VTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W R DG +P R +G +E + DAG+Y C A N G+ G+
Sbjct: 257 IIWRRADG---KPIARKARRHKSNGILE--IPNFQQEDAGLYECVAENSRGKNVARGQ-- 309
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ + +P +I+K + V EC+ G PKP W
Sbjct: 310 --------------------LTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKW 349
Query: 3418 LRD 3420
L++
Sbjct: 350 LKN 352
Score = 44.4 bits (100), Expect = 0.007
Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL-AGETANLTCSVKGKPV 3079
++ N++G S+ S I VG P+F L ++ ++ G + C K P
Sbjct: 382 YQCLAENKHGVIFSNAELSVIAVG-----PDFSRTLLKRVTLVKVGGEVVIECKPKASPK 436
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
P W K G ++ +E R+T +G L I ++ D G Y+C ATN G AS+ L
Sbjct: 437 PVYTW-KKGRDILKENERITISEDGN---LRIINVTKSDAGSYTCIATNHFGTASSTGNL 492
Query: 3140 AVVTDRT 3146
VV D T
Sbjct: 493 -VVKDPT 498
Score = 44.0 bits (99), Expect = 0.010
Identities = 55/214 (25%), Positives = 83/214 (38%), Gaps = 19/214 (8%)
Query: 2594 PVFSTFLTDR-TAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
P FS L R T V+ G V + C +S P TW + +L + DG L
Sbjct: 406 PDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITIS-EDG--NL 462
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++N SD+ Y+C N G S++ NL V +PP S D +
Sbjct: 463 RIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVM-VPP----SSMDV--TVGESI 515
Query: 2712 VLECRIRGQPLPKI--TWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
VL C++ I TW + I D ++ D L I N + +G Y
Sbjct: 516 VLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYV 575
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
C + SV D+++ + R P VT ++
Sbjct: 576 CMVQTSV--DRLSAAADLIVRGPPGPPEAVTIDE 607
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 97.9 bits (233), Expect = 6e-19
Identities = 91/318 (28%), Positives = 134/318 (42%), Gaps = 44/318 (13%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQ 3101
G+ G+ +++ P + G T L C G PVP ++W + +G + +A R S
Sbjct: 218 GVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKS- 276
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
NG L I + +D G Y C A N+ GK +L
Sbjct: 277 -NGI---LEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQ----------------- 315
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
P + ++ D V V C+ G P P W K+GE ++ R++ Q EQ
Sbjct: 316 ------PNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLL---TRDRIQIEQ 366
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE 3281
TL I NL D G+Y+ A N G + + L V V P+F L L +
Sbjct: 367 -GTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSV-----IAVGPDFSRTLLKRVTLVK 420
Query: 3282 -GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
G E+ I +A P TW + L+ + R +T+ DG L + VT DAG YT
Sbjct: 421 VGGEVVIECKPKASPKPVYTWKKGRDILKENER--ITISEDGN--LRIINVTKSDAGSYT 476
Query: 3341 CTASNEVGRASTSGKVEV 3358
C A+N G AS++G + V
Sbjct: 477 CIATNHFGTASSTGNLVV 494
Score = 78.6 bits (185), Expect = 4e-13
Identities = 75/301 (24%), Positives = 125/301 (41%), Gaps = 42/301 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
+G+ VKL C + + PT+ W R +G + K + K +G+ LE+ N D+ Y
Sbjct: 239 KGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKS--NGI--LEIPNFQQEDAGLYE 294
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C EN G L Y P + + I D E + EC+ G+P P
Sbjct: 295 CVAENSRGKNVARGQLTFYAQ-------PNWIQKINDIHVAMEENVFWECKANGRPKPTY 347
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ + + + R Q + G + I N + D+G Y C AEN H V F+
Sbjct: 348 KWLKNGEPLLTRDRIQ---IEQGTLNITIVNLS--DAGMYQCLAENK-------HGVIFS 395
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEW 2845
E V +T + R +L V GG + ++ + + P V
Sbjct: 396 NAELSVIAVGPDFSRTLLKRVTL---------------VKVGGEVVIECKPKASPKPVYT 440
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
++GR + + N R+ + + L + +VT++++G YTC A + G + V P
Sbjct: 441 WKKGRDILK--ENERITISED-GNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDP 497
Query: 2906 S 2906
+
Sbjct: 498 T 498
Score = 64.1 bits (149), Expect = 8e-09
Identities = 89/347 (25%), Positives = 139/347 (40%), Gaps = 61/347 (17%)
Query: 3084 WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
W+ N + ++ R SQ G L I + D G Y+C TNT VT
Sbjct: 157 WIFNEYPSYQDNRRFVSQETGN---LYIAKVEKSDVGNYTCVVTNT------------VT 201
Query: 3144 DRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVSWY 3202
+ V L R+ V G+Y P+ ++ + A V+L C +G+P P + W
Sbjct: 202 NHKVLGPPTPLIL-RNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWR 260
Query: 3203 K-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI 3261
+ DG+ + RR+K LEI +D G+YE A N+ G V +
Sbjct: 261 RADGKPIARKARRHKSNG----ILEIPNFQQEDAGLYECVAENSRGKN------VARGQL 310
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
Y P + + ++ E + + P W ++G ++T DR
Sbjct: 311 TFYAQPNWIQKINDIHVAME-ENVFWECKANGRPKPTYKWLKNG-------EPLLTRDRI 362
Query: 3322 GQIE---LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
QIE L + V DAG+Y C A N+ G ++ ++ VI + PD
Sbjct: 363 -QIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI-------------AVGPD- 407
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL--RDFLK 3423
+S+ + R + + G V+IEC+ PKP W RD LK
Sbjct: 408 -FSRTLL----KRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILK 449
Score = 57.6 bits (133), Expect = 7e-07
Identities = 75/299 (25%), Positives = 123/299 (41%), Gaps = 46/299 (15%)
Query: 2651 LEVLNAVPSDSAEYSCTVEN---ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + SD Y+C V N + + L + P +T A
Sbjct: 179 LYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTA 238
Query: 2708 ENELV-LECRIRGQPLPKITWFK-DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ V LEC G P+P I W + D K I R + ++G+ L I N ED+G Y
Sbjct: 239 KGATVKLECFALGNPVPTIIWRRADGKPIARKARR---HKSNGI--LEIPNFQQEDAGLY 293
Query: 2766 TCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVA 2825
C AENS G+ NV + T A+ P++ + D VA
Sbjct: 294 ECVAENS------------RGK------NVARGQLTFYAQ-------PNWIQKINDIHVA 328
Query: 2826 RGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYT 2884
+ + + G P +WL+ G + R+ +EQG TL ++ V +++G+Y
Sbjct: 329 MEENVFWECKANGRPKPTYKWLKNGEPLLT---RDRIQIEQG--TLNITIVNLSDAGMYQ 383
Query: 2885 CRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
C A + HG + NA ++V+ D ++ ++ L+ VG ++ I + + PKP
Sbjct: 384 CLAENKHGVIFSNAELSVIAVGP-DFSRTLL----KRVTLVKVGGEVVIECKPKASPKP 437
Score = 55.2 bits (127), Expect = 4e-06
Identities = 70/294 (23%), Positives = 106/294 (36%), Gaps = 40/294 (13%)
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C G+P P W+KNG + Q L I +N+ D G Y C A N HG
Sbjct: 337 CKANGRPKPTYKWLKNGEPLLTRDRIQIEQGT-----LNITIVNLSDAGMYQCLAENKHG 391
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
+ A L+V+ + LKR +V G+ V + C+
Sbjct: 392 VIFSNAELSVIAVGPDFSRTL-LKRVTLVKVGGE-------------------VVIECKP 431
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
SP P +W K G +++ + R ++ L I D G Y A N+ G S
Sbjct: 432 KASPKPVYTW-KKGRDILKENERITISEDG--NLRIINVTKSDAGSYTCIATNHFGTASS 488
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV--TWYRDGVRL- 3308
LVV R V P + G+ + + V S+ + TW +G +
Sbjct: 489 TGNLVVKDPTRVMVPPS-------SMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 541
Query: 3309 --RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
R +D +L + + + AG Y C V R S + + V G
Sbjct: 542 FDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRG 595
Score = 52.0 bits (119), Expect = 4e-05
Identities = 71/250 (28%), Positives = 104/250 (41%), Gaps = 49/250 (19%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V+L C+V G+P P + W +G +V D + +Y + L P D G Y+ TA
Sbjct: 46 VKLNCEVKGNPKPHIRWKLNGTDV--DTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTAT 103
Query: 3244 NNSGA-VSCHCGL---VVDK---------GIRAYVAPEFCCGLEPLYKLHEGDELRISAV 3290
N+ G VS L +D +R CG P H G EL + +
Sbjct: 104 NSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPP----HSG-ELSYAWI 158
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
YPS Y+D +RR + G L +A V D G YTC +N V
Sbjct: 159 FNEYPS-----YQD------NRRFVS--QETG--NLYIAKVEKSDVGNYTCVVTNTV--- 200
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVG 3409
T+ K V+G P P ++ + V EP ++ P + +G TV +EC +G
Sbjct: 201 -TNHK--VLG------PPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALG 251
Query: 3410 DPKPDVYWLR 3419
+P P + W R
Sbjct: 252 NPVPTIIWRR 261
Score = 50.4 bits (115), Expect = 1e-04
Identities = 78/345 (22%), Positives = 130/345 (37%), Gaps = 49/345 (14%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
E +VKL C V + P + W NG +D + +R +V+G + + N D+ Y C
Sbjct: 42 EEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKT-QDAGTYQC 100
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP-- 2723
T N G I S K+ ++ F R T + + +VL C G P
Sbjct: 101 TATNSFGTI-VSREAKLQFAY-----LDNFKTRTRSTVSVRRGQGMVLLC---GPPPHSG 151
Query: 2724 --KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
W ++ D R +++ L I D G YTC N+V
Sbjct: 152 ELSYAWIFNEYPSYQDNRR---FVSQETGNLYIAKVEKSDVGNYTCVVTNTV-------- 200
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
T + P + + + F + A+G T+ L+ G P
Sbjct: 201 ---TNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETV---PTAKGATVKLECFALGNPV 254
Query: 2842 -RVEWLR-EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG-NVDMNA 2898
+ W R +G+ + R AR G+ L + + + ++GLY C A ++ G NV
Sbjct: 255 PTIIWRRADGKPIA---RKARRHKSNGI--LEIPNFQQEDAGLYECVAENSRGKNVARGQ 309
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
QP+ + + DI +++ E++ + G PKP
Sbjct: 310 LTFYAQPNWI---------QKINDIHVAMEENVFWECKANGRPKP 345
Score = 45.2 bits (102), Expect = 0.004
Identities = 82/363 (22%), Positives = 130/363 (35%), Gaps = 70/363 (19%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN-IDDEGRYSCEATN 3128
L C VKG P P + W NG +V+ M +++ + L I + N D G Y C ATN
Sbjct: 48 LNCEVKGNPKPHIRWKLNGTDVDT---GMDFRYSVVEGSLLINNPNKTQDAGTYQCTATN 104
Query: 3129 THGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRL 3187
+ G +V+ R A+++ Y F R R V+ + L
Sbjct: 105 SFG--------TIVS--------------REAKLQFAYLDNFKTRTRSTVSVRRGQGMVL 142
Query: 3188 TCQVIGSPPP-----KVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
C PPP +W + D RR + ++ L IA D G Y
Sbjct: 143 LC----GPPPHSGELSYAWIFNEYPSYQDNRR--FVSQETGNLYIAKVEKSDVGNYTCVV 196
Query: 3243 RN---NSGAVSCHCGLVV-DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
N N + L++ + G+ P+ +G +++ P
Sbjct: 197 TNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPT 256
Query: 3299 VTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W R DG +P R +G +E + DAG+Y C A N G+ G+
Sbjct: 257 IIWRRADG---KPIARKARRHKSNGILE--IPNFQQEDAGLYECVAENSRGKNVARGQ-- 309
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ + +P +I+K + V EC+ G PKP W
Sbjct: 310 --------------------LTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKW 349
Query: 3418 LRD 3420
L++
Sbjct: 350 LKN 352
Score = 44.4 bits (100), Expect = 0.007
Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL-AGETANLTCSVKGKPV 3079
++ N++G S+ S I VG P+F L ++ ++ G + C K P
Sbjct: 382 YQCLAENKHGVIFSNAELSVIAVG-----PDFSRTLLKRVTLVKVGGEVVIECKPKASPK 436
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
P W K G ++ +E R+T +G L I ++ D G Y+C ATN G AS+ L
Sbjct: 437 PVYTW-KKGRDILKENERITISEDGN---LRIINVTKSDAGSYTCIATNHFGTASSTGNL 492
Query: 3140 AVVTDRT 3146
VV D T
Sbjct: 493 -VVKDPT 498
Score = 44.0 bits (99), Expect = 0.010
Identities = 55/214 (25%), Positives = 83/214 (38%), Gaps = 19/214 (8%)
Query: 2594 PVFSTFLTDR-TAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
P FS L R T V+ G V + C +S P TW + +L + DG L
Sbjct: 406 PDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITIS-EDG--NL 462
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++N SD+ Y+C N G S++ NL V +PP S D +
Sbjct: 463 RIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVM-VPP----SSMDV--TVGESI 515
Query: 2712 VLECRIRGQPLPKI--TWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
VL C++ I TW + I D ++ D L I N + +G Y
Sbjct: 516 VLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYV 575
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
C + SV D+++ + R P VT ++
Sbjct: 576 CMVQTSV--DRLSAAADLIVRGPPGPPEAVTIDE 607
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 97.5 bits (232), Expect = 7e-19
Identities = 97/352 (27%), Positives = 143/352 (40%), Gaps = 43/352 (12%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++ D G+ V TC + P + W RN L K R L+D TL
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-TLM 320
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N +D Y C +N G + T +V + SP PTF ++T L +
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQ---EVTLRYFGSPARPTFVIQPQNTEVLVGESVT 377
Query: 2713 LECRIRGQPLPKITWFKDDK-QIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC G P P+I+W + D+ +P D R G L I N DSG Y C A N
Sbjct: 378 LECSATGHPPPRISWTRGDRTPLPVDPRVN--ITPSG--GLYIQNVVQGDSGEYACSATN 433
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
++ + T F+ +V A P F D V G T+
Sbjct: 434 NIDSVHATAFI------------IVQA-------------LPQFTVTPQDRVVIEGQTVD 468
Query: 2832 LQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
Q E +G P V +G S V R + + G TL +S V + G Y C+A +
Sbjct: 469 FQCEAKGNPPPVIAWTKGGSQLSVDRR-HLVLSSG--TLRISGVALHDQGQYECQAVNII 525
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G+ + A +T VQP + + D + VG ++ + +QGEP+P
Sbjct: 526 GSQKVVAHLT-VQP-----RVTPVFASIPSDTTVEVGANVQLPCSSQGEPEP 571
Score = 91.1 bits (216), Expect = 6e-17
Identities = 84/305 (27%), Positives = 127/305 (41%), Gaps = 39/305 (12%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RP FV I P ++L GE+ L CS G P P + W + R+ +G
Sbjct: 358 RPTFV-IQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG--- 413
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+++ D G Y+C ATN S +A ++ P
Sbjct: 414 LYIQNVVQGDSGEYACSATNNID--SVHATAFIIVQAL---------------------P 450
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
QFT+ +DR V V C+ G+PPP ++W K G ++ D+R TL I+
Sbjct: 451 QFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSS---GTLRIS 507
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
L D G YE A N G+ +V ++ V P F + + G +++
Sbjct: 508 GVALHDQGQYECQAVNIIGSQK----VVAHLTVQPRVTPVF-ASIPSDTTVEVGANVQLP 562
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ P +TW +DGV++ S + + +G L + V DAG Y C A N +G
Sbjct: 563 CSSQGEPEPAITWNKDGVQVTESGK--FHISPEG--FLTINDVGPADAGRYECVARNTIG 618
Query: 3349 RASTS 3353
AS S
Sbjct: 619 SASVS 623
Score = 84.2 bits (199), Expect = 7e-15
Identities = 88/369 (23%), Positives = 144/369 (39%), Gaps = 56/369 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +G T TC +G P P ++W++N +E+ + + + D L I++
Sbjct: 269 PQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD--DGTLMIQNTQE 326
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+G Y C A N G+ T VT R + + A+ P F ++ ++
Sbjct: 327 TDQGIYQCMAKNVAGEVKTQE----VTLR-YFGSPAR--------------PTFVIQPQN 367
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYK-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
V V L C G PPP++SW + D + D R N + + D
Sbjct: 368 TEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQ---GDS 424
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y +A NN +V ++V P+F + + EG + + P
Sbjct: 425 GEYACSATNNIDSVHATAFIIVQ------ALPQFTVTPQDRVVI-EGQTVDFQCEAKGNP 477
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W + G +L RR ++ L ++ V D G Y C A N +G S K
Sbjct: 478 PPVIAWTKGGSQLSVDRRHLVL----SSGTLRISGVALHDQGQYECQAVNIIG----SQK 529
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T +PR+ PV F P + G V + C G+P+P +
Sbjct: 530 VV---AHLTVQPRVTPV-------------FASIPSDTTVEVGANVQLPCSSQGEPEPAI 573
Query: 3416 YWLRDFLKV 3424
W +D ++V
Sbjct: 574 TWNKDGVQV 582
Score = 79.0 bits (186), Expect = 3e-13
Identities = 62/225 (27%), Positives = 92/225 (40%), Gaps = 16/225 (7%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ DR +EG V C + P + W + G L R+ LV TL +
Sbjct: 450 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRI 506
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
D +Y C N G+ A+L V P + P F DT + L
Sbjct: 507 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR-----VTPVFASIPSDTTVEVGANVQL 561
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C +G+P P ITW KD Q+ G++ +G L I++ P D+G Y C A N++
Sbjct: 562 PCSSQGEPEPAITWNKDGVQVTESGKFH--ISPEGF--LTINDVGPADAGRYECVARNTI 617
Query: 2774 WTDQITHF--VNFTGRESQVSPNVVTAEKTRIAR--QSLESRRPH 2814
+ ++ VN P V T+ IA +++ S R H
Sbjct: 618 GSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTH 662
Score = 71.3 bits (167), Expect = 6e-11
Identities = 66/260 (25%), Positives = 102/260 (39%), Gaps = 37/260 (14%)
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
+ ITP N+ QG+ + + N +S ++ I V P+F + P
Sbjct: 406 VNITPSGGLYIQNVVQGDSGEYACSATNNI---DSVHATAFIIVQAL---PQFT-VTPQD 458
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
++ G+T + C KG P P + W K G ++ + + L I + + D+
Sbjct: 459 RVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG----TLRISGVALHDQ 514
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C+A N G A L V T P F D V
Sbjct: 515 GQYECQAVNIIGSQKVVAHLTVQPRVT---------------------PVFASIPSDTTV 553
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL-EIAPTNLDDGGVY 3238
+ V+L C G P P ++W KDG +V + + E F T+ ++ P D G Y
Sbjct: 554 EVGANVQLPCSSQGEPEPAITWNKDGVQVT-ESGKFHISPEGFLTINDVGPA---DAGRY 609
Query: 3239 EVTARNNSGAVSCHCGLVVD 3258
E ARN G+ S L V+
Sbjct: 610 ECVARNTIGSASVSMVLSVN 629
Score = 69.3 bits (162), Expect = 2e-10
Identities = 77/327 (23%), Positives = 129/327 (39%), Gaps = 42/327 (12%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
S +P F + + G V L CS P ++W R G + R +
Sbjct: 355 SPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRVNITPS-G 412
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
L + N V DS EY+C+ N ++ +A + V P FT + +D +
Sbjct: 413 GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL-------PQFTVTPQDRVVIEGQ 465
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ +C +G P P I W K Q+ D R+ L+ G R I D G Y C+A
Sbjct: 466 TVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH--LVLSSGTLR--ISGVALHDQGQYECQA 521
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N + + ++ + V P V P F ++ +D V G
Sbjct: 522 VNIIGSQKVVAHLT-------VQPRVT----------------PVFASIPSDTTVEVGAN 558
Query: 2830 IGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAW 2888
+ L +G P + W ++G VTE + + + + L ++DV ++G Y C A
Sbjct: 559 VQLPCSSQGEPEPAITWNKDGVQVTE---SGKFHISPEGF-LTINDVGPADAGRYECVAR 614
Query: 2889 SAHGNVDMNAAITVVQPS-DLDGKPAV 2914
+ G+ ++ ++V P +G P V
Sbjct: 615 NTIGSASVSMVLSVNVPDVSRNGDPFV 641
Score = 56.4 bits (130), Expect = 2e-06
Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 35/255 (13%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY--DKRRNKYQDEQFHTL 3225
P+ T +D V + V TC+ G+P P++ W ++ E+ D R N D TL
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTL 319
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDE 3284
I T D G+Y+ A+N +G V V + + P F ++P ++ G+
Sbjct: 320 MIQNTQETDQGIYQCMAKNVAGEVKTQ--EVTLRYFGSPARPTFV--IQPQNTEVLVGES 375
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +P ++W R P + G L + V D+G Y C+A+
Sbjct: 376 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSAT 432
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
N + + + V P F P+ EG TV +
Sbjct: 433 NNIDSVHATAFIIV----------------------QALPQFTVTPQDRVVIEGQTVDFQ 470
Query: 3405 CEVVGDPKPDVYWLR 3419
CE G+P P + W +
Sbjct: 471 CEAKGNPPPVIAWTK 485
Score = 46.4 bits (105), Expect = 0.002
Identities = 36/157 (22%), Positives = 60/157 (38%), Gaps = 7/157 (4%)
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARV 2861
I + L RP + D V G T+ G P + WLR ++ +
Sbjct: 253 ITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLN 312
Query: 2862 FVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEK 2921
++ G TL + + ET+ G+Y C A + G V ++ +P ++
Sbjct: 313 LLDDG--TLMIQNTQETDQGIYQCMAKNVAGEVKTQE--VTLRYFGSPARPTFVIQPQNT 368
Query: 2922 DILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
++L VGE + + G P P+ R P VD
Sbjct: 369 EVL--VGESVTLECSATGHPPPRISWTRGDRTPLPVD 403
Score = 41.9 bits (94), Expect = 0.039
Identities = 15/47 (31%), Positives = 27/47 (57%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
I+P+ + P +P+ ++ G+TV C G+PKP++ WLR+
Sbjct: 253 ITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRN 299
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 97.5 bits (232), Expect = 7e-19
Identities = 97/352 (27%), Positives = 143/352 (40%), Gaps = 43/352 (12%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++ D G+ V TC + P + W RN L K R L+D TL
Sbjct: 240 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-TLM 298
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N +D Y C +N G + T +V + SP PTF ++T L +
Sbjct: 299 IQNTQETDQGIYQCMAKNVAGEVKTQ---EVTLRYFGSPARPTFVIQPQNTEVLVGESVT 355
Query: 2713 LECRIRGQPLPKITWFKDDK-QIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC G P P+I+W + D+ +P D R G L I N DSG Y C A N
Sbjct: 356 LECSATGHPPPRISWTRGDRTPLPVDPRVN--ITPSG--GLYIQNVVQGDSGEYACSATN 411
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
++ + T F+ +V A P F D V G T+
Sbjct: 412 NIDSVHATAFI------------IVQA-------------LPQFTVTPQDRVVIEGQTVD 446
Query: 2832 LQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
Q E +G P V +G S V R + + G TL +S V + G Y C+A +
Sbjct: 447 FQCEAKGNPPPVIAWTKGGSQLSVDRR-HLVLSSG--TLRISGVALHDQGQYECQAVNII 503
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G+ + A +T VQP + + D + VG ++ + +QGEP+P
Sbjct: 504 GSQKVVAHLT-VQP-----RVTPVFASIPSDTTVEVGANVQLPCSSQGEPEP 549
Score = 91.1 bits (216), Expect = 6e-17
Identities = 84/305 (27%), Positives = 127/305 (41%), Gaps = 39/305 (12%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RP FV I P ++L GE+ L CS G P P + W + R+ +G
Sbjct: 336 RPTFV-IQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG--- 391
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+++ D G Y+C ATN S +A ++ P
Sbjct: 392 LYIQNVVQGDSGEYACSATNNID--SVHATAFIIVQAL---------------------P 428
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
QFT+ +DR V V C+ G+PPP ++W K G ++ D+R TL I+
Sbjct: 429 QFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSS---GTLRIS 485
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
L D G YE A N G+ +V ++ V P F + + G +++
Sbjct: 486 GVALHDQGQYECQAVNIIGSQK----VVAHLTVQPRVTPVF-ASIPSDTTVEVGANVQLP 540
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ P +TW +DGV++ S + + +G L + V DAG Y C A N +G
Sbjct: 541 CSSQGEPEPAITWNKDGVQVTESGK--FHISPEG--FLTINDVGPADAGRYECVARNTIG 596
Query: 3349 RASTS 3353
AS S
Sbjct: 597 SASVS 601
Score = 84.2 bits (199), Expect = 7e-15
Identities = 88/369 (23%), Positives = 144/369 (39%), Gaps = 56/369 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +G T TC +G P P ++W++N +E+ + + + D L I++
Sbjct: 247 PQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD--DGTLMIQNTQE 304
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+G Y C A N G+ T VT R + + A+ P F ++ ++
Sbjct: 305 TDQGIYQCMAKNVAGEVKTQE----VTLR-YFGSPAR--------------PTFVIQPQN 345
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYK-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
V V L C G PPP++SW + D + D R N + + D
Sbjct: 346 TEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQ---GDS 402
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y +A NN +V ++V P+F + + EG + + P
Sbjct: 403 GEYACSATNNIDSVHATAFIIVQ------ALPQFTVTPQDRVVI-EGQTVDFQCEAKGNP 455
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W + G +L RR ++ L ++ V D G Y C A N +G S K
Sbjct: 456 PPVIAWTKGGSQLSVDRRHLVL----SSGTLRISGVALHDQGQYECQAVNIIG----SQK 507
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T +PR+ PV F P + G V + C G+P+P +
Sbjct: 508 VV---AHLTVQPRVTPV-------------FASIPSDTTVEVGANVQLPCSSQGEPEPAI 551
Query: 3416 YWLRDFLKV 3424
W +D ++V
Sbjct: 552 TWNKDGVQV 560
Score = 79.0 bits (186), Expect = 3e-13
Identities = 62/225 (27%), Positives = 92/225 (40%), Gaps = 16/225 (7%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ DR +EG V C + P + W + G L R+ LV TL +
Sbjct: 428 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRI 484
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
D +Y C N G+ A+L V P + P F DT + L
Sbjct: 485 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR-----VTPVFASIPSDTTVEVGANVQL 539
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C +G+P P ITW KD Q+ G++ +G L I++ P D+G Y C A N++
Sbjct: 540 PCSSQGEPEPAITWNKDGVQVTESGKFH--ISPEGF--LTINDVGPADAGRYECVARNTI 595
Query: 2774 WTDQITHF--VNFTGRESQVSPNVVTAEKTRIAR--QSLESRRPH 2814
+ ++ VN P V T+ IA +++ S R H
Sbjct: 596 GSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTH 640
Score = 71.3 bits (167), Expect = 6e-11
Identities = 66/260 (25%), Positives = 102/260 (39%), Gaps = 37/260 (14%)
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
+ ITP N+ QG+ + + N +S ++ I V P+F + P
Sbjct: 384 VNITPSGGLYIQNVVQGDSGEYACSATNNI---DSVHATAFIIVQAL---PQFT-VTPQD 436
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
++ G+T + C KG P P + W K G ++ + + L I + + D+
Sbjct: 437 RVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG----TLRISGVALHDQ 492
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C+A N G A L V T P F D V
Sbjct: 493 GQYECQAVNIIGSQKVVAHLTVQPRVT---------------------PVFASIPSDTTV 531
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL-EIAPTNLDDGGVY 3238
+ V+L C G P P ++W KDG +V + + E F T+ ++ P D G Y
Sbjct: 532 EVGANVQLPCSSQGEPEPAITWNKDGVQVT-ESGKFHISPEGFLTINDVGPA---DAGRY 587
Query: 3239 EVTARNNSGAVSCHCGLVVD 3258
E ARN G+ S L V+
Sbjct: 588 ECVARNTIGSASVSMVLSVN 607
Score = 69.3 bits (162), Expect = 2e-10
Identities = 77/327 (23%), Positives = 129/327 (39%), Gaps = 42/327 (12%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
S +P F + + G V L CS P ++W R G + R +
Sbjct: 333 SPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRVNITPS-G 390
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
L + N V DS EY+C+ N ++ +A + V P FT + +D +
Sbjct: 391 GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL-------PQFTVTPQDRVVIEGQ 443
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ +C +G P P I W K Q+ D R+ L+ G R I D G Y C+A
Sbjct: 444 TVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH--LVLSSGTLR--ISGVALHDQGQYECQA 499
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N + + ++ + V P V P F ++ +D V G
Sbjct: 500 VNIIGSQKVVAHLT-------VQPRVT----------------PVFASIPSDTTVEVGAN 536
Query: 2830 IGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAW 2888
+ L +G P + W ++G VTE + + + + L ++DV ++G Y C A
Sbjct: 537 VQLPCSSQGEPEPAITWNKDGVQVTE---SGKFHISPEGF-LTINDVGPADAGRYECVAR 592
Query: 2889 SAHGNVDMNAAITVVQPS-DLDGKPAV 2914
+ G+ ++ ++V P +G P V
Sbjct: 593 NTIGSASVSMVLSVNVPDVSRNGDPFV 619
Score = 56.4 bits (130), Expect = 2e-06
Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 35/255 (13%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY--DKRRNKYQDEQFHTL 3225
P+ T +D V + V TC+ G+P P++ W ++ E+ D R N D TL
Sbjct: 241 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTL 297
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDE 3284
I T D G+Y+ A+N +G V V + + P F ++P ++ G+
Sbjct: 298 MIQNTQETDQGIYQCMAKNVAGEVKTQ--EVTLRYFGSPARPTFV--IQPQNTEVLVGES 353
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +P ++W R P + G L + V D+G Y C+A+
Sbjct: 354 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSAT 410
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
N + + + V P F P+ EG TV +
Sbjct: 411 NNIDSVHATAFIIV----------------------QALPQFTVTPQDRVVIEGQTVDFQ 448
Query: 3405 CEVVGDPKPDVYWLR 3419
CE G+P P + W +
Sbjct: 449 CEAKGNPPPVIAWTK 463
Score = 46.4 bits (105), Expect = 0.002
Identities = 36/157 (22%), Positives = 60/157 (38%), Gaps = 7/157 (4%)
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARV 2861
I + L RP + D V G T+ G P + WLR ++ +
Sbjct: 231 ITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLN 290
Query: 2862 FVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEK 2921
++ G TL + + ET+ G+Y C A + G V ++ +P ++
Sbjct: 291 LLDDG--TLMIQNTQETDQGIYQCMAKNVAGEVKTQE--VTLRYFGSPARPTFVIQPQNT 346
Query: 2922 DILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
++L VGE + + G P P+ R P VD
Sbjct: 347 EVL--VGESVTLECSATGHPPPRISWTRGDRTPLPVD 381
Score = 41.9 bits (94), Expect = 0.039
Identities = 15/47 (31%), Positives = 27/47 (57%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
I+P+ + P +P+ ++ G+TV C G+PKP++ WLR+
Sbjct: 231 ITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRN 277
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated antigen
MG50 protein.
Length = 1496
Score = 97.5 bits (232), Expect = 7e-19
Identities = 97/352 (27%), Positives = 143/352 (40%), Gaps = 43/352 (12%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++ D G+ V TC + P + W RN L K R L+D TL
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-TLM 320
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N +D Y C +N G + T +V + SP PTF ++T L +
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQ---EVTLRYFGSPARPTFVIQPQNTEVLVGESVT 377
Query: 2713 LECRIRGQPLPKITWFKDDK-QIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC G P P+I+W + D+ +P D R G L I N DSG Y C A N
Sbjct: 378 LECSATGHPPPRISWTRGDRTPLPVDPRVN--ITPSG--GLYIQNVVQGDSGEYACSATN 433
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
++ + T F+ +V A P F D V G T+
Sbjct: 434 NIDSVHATAFI------------IVQA-------------LPQFTVTPQDRVVIEGQTVD 468
Query: 2832 LQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
Q E +G P V +G S V R + + G TL +S V + G Y C+A +
Sbjct: 469 FQCEAKGNPPPVIAWTKGGSQLSVDRR-HLVLSSG--TLRISGVALHDQGQYECQAVNII 525
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G+ + A +T VQP + + D + VG ++ + +QGEP+P
Sbjct: 526 GSQKVVAHLT-VQP-----RVTPVFASIPSDTTVEVGANVQLPCSSQGEPEP 571
Score = 91.1 bits (216), Expect = 6e-17
Identities = 84/305 (27%), Positives = 127/305 (41%), Gaps = 39/305 (12%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RP FV I P ++L GE+ L CS G P P + W + R+ +G
Sbjct: 358 RPTFV-IQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG--- 413
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+++ D G Y+C ATN S +A ++ P
Sbjct: 414 LYIQNVVQGDSGEYACSATNNID--SVHATAFIIVQAL---------------------P 450
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
QFT+ +DR V V C+ G+PPP ++W K G ++ D+R TL I+
Sbjct: 451 QFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSS---GTLRIS 507
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
L D G YE A N G+ +V ++ V P F + + G +++
Sbjct: 508 GVALHDQGQYECQAVNIIGSQK----VVAHLTVQPRVTPVF-ASIPSDTTVEVGANVQLP 562
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ P +TW +DGV++ S + + +G L + V DAG Y C A N +G
Sbjct: 563 CSSQGEPEPAITWNKDGVQVTESGK--FHISPEG--FLTINDVGPADAGRYECVARNTIG 618
Query: 3349 RASTS 3353
AS S
Sbjct: 619 SASVS 623
Score = 84.2 bits (199), Expect = 7e-15
Identities = 88/369 (23%), Positives = 144/369 (39%), Gaps = 56/369 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +G T TC +G P P ++W++N +E+ + + + D L I++
Sbjct: 269 PQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD--DGTLMIQNTQE 326
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+G Y C A N G+ T VT R + + A+ P F ++ ++
Sbjct: 327 TDQGIYQCMAKNVAGEVKTQE----VTLR-YFGSPAR--------------PTFVIQPQN 367
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYK-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
V V L C G PPP++SW + D + D R N + + D
Sbjct: 368 TEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQ---GDS 424
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y +A NN +V ++V P+F + + EG + + P
Sbjct: 425 GEYACSATNNIDSVHATAFIIVQ------ALPQFTVTPQDRVVI-EGQTVDFQCEAKGNP 477
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W + G +L RR ++ L ++ V D G Y C A N +G S K
Sbjct: 478 PPVIAWTKGGSQLSVDRRHLVL----SSGTLRISGVALHDQGQYECQAVNIIG----SQK 529
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T +PR+ PV F P + G V + C G+P+P +
Sbjct: 530 VV---AHLTVQPRVTPV-------------FASIPSDTTVEVGANVQLPCSSQGEPEPAI 573
Query: 3416 YWLRDFLKV 3424
W +D ++V
Sbjct: 574 TWNKDGVQV 582
Score = 79.0 bits (186), Expect = 3e-13
Identities = 62/225 (27%), Positives = 92/225 (40%), Gaps = 16/225 (7%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ DR +EG V C + P + W + G L R+ LV TL +
Sbjct: 450 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRI 506
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
D +Y C N G+ A+L V P + P F DT + L
Sbjct: 507 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR-----VTPVFASIPSDTTVEVGANVQL 561
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C +G+P P ITW KD Q+ G++ +G L I++ P D+G Y C A N++
Sbjct: 562 PCSSQGEPEPAITWNKDGVQVTESGKFH--ISPEGF--LTINDVGPADAGRYECVARNTI 617
Query: 2774 WTDQITHF--VNFTGRESQVSPNVVTAEKTRIAR--QSLESRRPH 2814
+ ++ VN P V T+ IA +++ S R H
Sbjct: 618 GSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTH 662
Score = 71.3 bits (167), Expect = 6e-11
Identities = 66/260 (25%), Positives = 102/260 (39%), Gaps = 37/260 (14%)
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
+ ITP N+ QG+ + + N +S ++ I V P+F + P
Sbjct: 406 VNITPSGGLYIQNVVQGDSGEYACSATNNI---DSVHATAFIIVQAL---PQFT-VTPQD 458
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
++ G+T + C KG P P + W K G ++ + + L I + + D+
Sbjct: 459 RVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG----TLRISGVALHDQ 514
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C+A N G A L V T P F D V
Sbjct: 515 GQYECQAVNIIGSQKVVAHLTVQPRVT---------------------PVFASIPSDTTV 553
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL-EIAPTNLDDGGVY 3238
+ V+L C G P P ++W KDG +V + + E F T+ ++ P D G Y
Sbjct: 554 EVGANVQLPCSSQGEPEPAITWNKDGVQVT-ESGKFHISPEGFLTINDVGPA---DAGRY 609
Query: 3239 EVTARNNSGAVSCHCGLVVD 3258
E ARN G+ S L V+
Sbjct: 610 ECVARNTIGSASVSMVLSVN 629
Score = 69.3 bits (162), Expect = 2e-10
Identities = 77/327 (23%), Positives = 129/327 (39%), Gaps = 42/327 (12%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI 2649
S +P F + + G V L CS P ++W R G + R +
Sbjct: 355 SPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRVNITPS-G 412
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
L + N V DS EY+C+ N ++ +A + V P FT + +D +
Sbjct: 413 GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL-------PQFTVTPQDRVVIEGQ 465
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ +C +G P P I W K Q+ D R+ L+ G R I D G Y C+A
Sbjct: 466 TVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH--LVLSSGTLR--ISGVALHDQGQYECQA 521
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N + + ++ + V P V P F ++ +D V G
Sbjct: 522 VNIIGSQKVVAHLT-------VQPRVT----------------PVFASIPSDTTVEVGAN 558
Query: 2830 IGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAW 2888
+ L +G P + W ++G VTE + + + + L ++DV ++G Y C A
Sbjct: 559 VQLPCSSQGEPEPAITWNKDGVQVTE---SGKFHISPEGF-LTINDVGPADAGRYECVAR 614
Query: 2889 SAHGNVDMNAAITVVQPS-DLDGKPAV 2914
+ G+ ++ ++V P +G P V
Sbjct: 615 NTIGSASVSMVLSVNVPDVSRNGDPFV 641
Score = 56.4 bits (130), Expect = 2e-06
Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 35/255 (13%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY--DKRRNKYQDEQFHTL 3225
P+ T +D V + V TC+ G+P P++ W ++ E+ D R N D TL
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTL 319
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDE 3284
I T D G+Y+ A+N +G V V + + P F ++P ++ G+
Sbjct: 320 MIQNTQETDQGIYQCMAKNVAGEVKTQ--EVTLRYFGSPARPTFV--IQPQNTEVLVGES 375
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +P ++W R P + G L + V D+G Y C+A+
Sbjct: 376 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSAT 432
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
N + + + V P F P+ EG TV +
Sbjct: 433 NNIDSVHATAFIIV----------------------QALPQFTVTPQDRVVIEGQTVDFQ 470
Query: 3405 CEVVGDPKPDVYWLR 3419
CE G+P P + W +
Sbjct: 471 CEAKGNPPPVIAWTK 485
Score = 46.4 bits (105), Expect = 0.002
Identities = 36/157 (22%), Positives = 60/157 (38%), Gaps = 7/157 (4%)
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARV 2861
I + L RP + D V G T+ G P + WLR ++ +
Sbjct: 253 ITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLN 312
Query: 2862 FVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEK 2921
++ G TL + + ET+ G+Y C A + G V ++ +P ++
Sbjct: 313 LLDDG--TLMIQNTQETDQGIYQCMAKNVAGEVKTQE--VTLRYFGSPARPTFVIQPQNT 368
Query: 2922 DILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
++L VGE + + G P P+ R P VD
Sbjct: 369 EVL--VGESVTLECSATGHPPPRISWTRGDRTPLPVD 403
Score = 41.9 bits (94), Expect = 0.039
Identities = 15/47 (31%), Positives = 27/47 (57%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
I+P+ + P +P+ ++ G+TV C G+PKP++ WLR+
Sbjct: 253 ITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRN 299
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens cDNA
FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 96.7 bits (230), Expect = 1e-18
Identities = 89/368 (24%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + NL C V+G P P ++W K+ +V E + T NG L + +D
Sbjct: 441 VSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVN-NGR--ILKLFRATPEDA 497
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL-RDRR 3178
GRYSC+A N G + Y + V+ T+ + ++P + ++ L RD
Sbjct: 498 GRYSCKAINIAGTSQKYFNIDVLVPPTI--------------IGTNFPNEVSVVLNRD-- 541
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L CQV G+P P + W+KDG+ + + D + L + +D G Y
Sbjct: 542 ------VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRY 594
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSV 3297
+ T N +G + L + Y+ P G + + +++ P
Sbjct: 595 QCTVSNAAGKQAKDIKLTI------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMP 648
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TWY+DG + S +A+ +D+ + + A V+ D+ YTC +N G A S V+
Sbjct: 649 AITWYKDGQPIMSSSQALY-IDKGQYLHIPRAQVS--DSATYTCHVANVAGTAEKSFHVD 705
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V +PP++ + P + + ++ +EC+ G+P P + W
Sbjct: 706 VY---------VPPMIEGN----------LATPLNKQVVIAHSLTLECKAAGNPSPILTW 746
Query: 3418 LRDFLKVR 3425
L+D + V+
Sbjct: 747 LKDGVPVK 754
Score = 95.1 bits (226), Expect = 4e-18
Identities = 90/365 (24%), Positives = 149/365 (40%), Gaps = 48/365 (13%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P ++T +R A R++ C + PT+ W NG L + L DG + L
Sbjct: 339 EPPYNTTFQERVA--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LV 395
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT-FHLAENEL 2711
+ + P D+ EY C NE G NLKV+ +PP + T + N+L
Sbjct: 396 IASVTPYDNGEYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQL 448
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C + G P P I W+KD+ Q+ Q + +G L + TPED+G Y+CKA
Sbjct: 449 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT--VNNGRI-LKLFRATPEDAGRYSCKAI 505
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
N T Q + + V P ++ N + V +
Sbjct: 506 NIAGTSQ-----KYFNIDVLVPPTIIGT------------------NFPNEVSVVLNRDV 542
Query: 2831 GLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
L+ +++G P + W ++G+ + N + +++G L L + + G Y C +
Sbjct: 543 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL-LDRG-QVLHLKNARRNDKGRYQCTVSN 600
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A G + +T+ P + G G DI + + I + T+G P P A+
Sbjct: 601 AAGKQAKDIKLTIYIPPSIKG------GNVTTDISVLINSLIKLECETRGLPMP-AITWY 653
Query: 2950 IPGEP 2954
G+P
Sbjct: 654 KDGQP 658
Score = 93.5 bits (222), Expect = 1e-17
Identities = 95/366 (25%), Positives = 147/366 (40%), Gaps = 54/366 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P LK+ G+ ++ C+ +G P+P + W K G + + S +G L+I
Sbjct: 248 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATP 304
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G Y+C ATN G T L V TV ++E Y F R+ +
Sbjct: 305 SDAGIYTCVATNIAGTDETEITLHVQEPPTV------------EDLEPPYNTTFQERVAN 352
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R++ +P C G+P P + W +G E+ + E L IA D G
Sbjct: 353 QRIE--FP----CPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTLLVIASVTPYDNG 405
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y A N +G L V P E + + + VE
Sbjct: 406 EYICVAVNEAGTTERKYNLKVH-------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGT 458
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS + WY+D V++ S I T++ +G+I L L T DAG Y+C A N G +
Sbjct: 459 PSPIIMWYKDNVQVTES-STIQTVN-NGRI-LKLFRATPEDAGRYSCKAINIAGTSQKYF 515
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
++V+ +PP +I + P + R V +EC+V G P PD
Sbjct: 516 NIDVL---------VPPTIIGTNFPNEVSVVLNR-----------DVALECQVKGTPFPD 555
Query: 3415 VYWLRD 3420
++W +D
Sbjct: 556 IHWFKD 561
Score = 91.9 bits (218), Expect = 4e-17
Identities = 90/361 (24%), Positives = 143/361 (39%), Gaps = 47/361 (13%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L + G L C G P P V+W K G + + + ++ G D L + ++
Sbjct: 61 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA---GADGSLYVVSPGGEES 117
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C ATNT G A +L V V+ L +++ E+ V
Sbjct: 118 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS---------------V 162
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
A V L C+V PPP ++W K+ + + R+ + +++I T D G+Y
Sbjct: 163 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS--GSMKITETRTSDSGMYL 220
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G V+ L V +V P+ G + L K+ G + I + P +
Sbjct: 221 CVAINIAGNVTQAVKLNV------HVPPKIQRGPKHL-KVQVGQRVDIPCNAQGTPLPVI 273
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + G + ++ + DG L++ T DAG+YTC A+N G
Sbjct: 274 TWSKGGSTMLVDGEHHVS-NPDG--TLSIDQATPSDAGIYTCVATNIAGTDE-------- 322
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
T+ T + PP V + PY+ E + C G PKP + WL
Sbjct: 323 -TEITLHVQEPPTVEDLEPPYN--------TTFQERVANQRIEFPCPAKGTPKPTIKWLH 373
Query: 3420 D 3420
+
Sbjct: 374 N 374
Score = 91.1 bits (216), Expect = 6e-17
Identities = 73/279 (26%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C G P P + W+K+ V G + Q +G L I ++D GRY+C ATN
Sbjct: 917 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR--VLQIAKTLLEDAGRYTCVATNA 974
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G+ + +L V ++ +A L + V + PV+L C
Sbjct: 975 AGETQQHIQLHVHEPPSLEDAGKML---------------------NETVLVSNPVQLEC 1013
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G+P P ++WYKD + Q ++I + D G+Y+ A N++GA
Sbjct: 1014 KAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINSAGAT 1071
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
L V +VAP G + + + +R+ P+ +TW +DG +
Sbjct: 1072 ELFYSLQV------HVAPSI-SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVS 1124
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ L G+I LAL + D G YTC A N G
Sbjct: 1125 SFSNGLQVLS-GGRI-LALTSAQISDTGRYTCVAVNAAG 1161
Score = 86.2 bits (204), Expect = 2e-15
Identities = 87/342 (25%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ + G V L C V S P +TW + L+ L G ++++ SDS
Sbjct: 161 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDSGM 218
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G ++ + L V+ +PP R + + + C +G PLP
Sbjct: 219 YLCVAINIAGNVTQAVKLNVH-------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 271
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD--QITHF 2781
ITW K + DG + DG L+ID TP D+G YTC A N TD +IT
Sbjct: 272 VITWSKGGSTMLVDGEHHVSN-PDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLH 328
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V + P T + R+A Q +E P A+G PT
Sbjct: 329 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCP-----------AKG---------TPKPT 368
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++WL GR +T R + + + L ++ VT ++G Y C A + G + +
Sbjct: 369 -IKWLHNGRELTG--REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLK 425
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V P + K V ++ + + + N+ +G P P
Sbjct: 426 VHVPPVIKDKEQV------TNVSVLLNQLTNLFCEVEGTPSP 461
Score = 85.8 bits (203), Expect = 2e-15
Identities = 92/352 (26%), Positives = 142/352 (40%), Gaps = 49/352 (13%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
+ F + + V V L C V + P + W+++G L +L+D L + NA
Sbjct: 528 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 586
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFHLAENELV-LE 2714
+D Y CTV N G + L +Y IPP+ ++ + N L+ LE
Sbjct: 587 RRNDKGRYQCTVSNAAGKQAKDIKLTIY-------IPPSIKGGNVTTDISVLINSLIKLE 639
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C RG P+P ITW+KD + I S QA Y+ G L I DS TYTC N
Sbjct: 640 CETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAG 696
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT--DYQVARGGTIGL 2832
T + + V + V P + GN+ T + QV ++ L
Sbjct: 697 TAEKSFHV-----DVYVPPMIE-------------------GNLATPLNKQVVIAHSLTL 732
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P+ + WL++G V N + +E G L + E + G Y C A S
Sbjct: 733 ECKAAGNPSPILTWLKDG---VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 789
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ + V+ P PA+ G ++ V + + G P P
Sbjct: 790 GEKEIKYEVDVLVP------PAIEGGDETSYFIVMVNNLLELDCHVTGSPPP 835
Score = 85.4 bits (202), Expect = 3e-15
Identities = 91/342 (26%), Positives = 133/342 (38%), Gaps = 37/342 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C V G P P ++W+K+G V+E G NG L I + + G
Sbjct: 817 VMVNNLLELDCHVTGSPPPTIMWLKDGQLVDERDG-FKILLNGRK--LVIAQAQVSNTGL 873
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A NT G D K + E + V PP RV
Sbjct: 874 YRCMAANTAG-------------------DHKEEFEVTVHV----PPTIKSSGLSERVVV 910
Query: 3182 TY-PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
Y PV L C G P P ++W KD + V + K Q L+IA T L+D G Y
Sbjct: 911 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG-RVLQIAKTLLEDAGRYTC 969
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N +G H L V + A + L + +L A P +T
Sbjct: 970 VATNAAGETQQHIQLHVHEPPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPV--IT 1024
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV-I 3359
WY+D RL ++ L+R I++ A ++ DAG+Y C A N G ++V +
Sbjct: 1025 WYKDN-RLLSGSTSMTFLNRGQIIDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHV 1081
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
+ + VV++ V E I P + ++G V
Sbjct: 1082 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPV 1123
Score = 81.0 bits (191), Expect = 7e-14
Identities = 99/416 (23%), Positives = 150/416 (36%), Gaps = 64/416 (15%)
Query: 3016 GEEY-HFRVTPRNRYGWGESS-QTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCS 3073
GEE + T N G+ + Q + + + GD+ P ++ +LAGE L C
Sbjct: 114 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 173
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
VK P P + W K + + R T +G + I + D G Y C A N G
Sbjct: 174 VKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSDSGMYLCVAINIAGNV 230
Query: 3134 STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIG 3193
+ +L V PP+ + +VQ V + C G
Sbjct: 231 TQAVKLNV-----------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQG 267
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
+P P ++W K G ++ D + + TL I D G+Y A N +G
Sbjct: 268 TPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDETEI 325
Query: 3254 GLVVDKGIRAYVAPEFCCGLEPLYKLH-----EGDELRISAVVEAYPSVGVTWYRDGVRL 3308
L V + P LEP Y + + P + W +G L
Sbjct: 326 TLHVQE-------PPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL 378
Query: 3309 RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
I L+ DG + L +A+VT D G Y C A NE G ++V
Sbjct: 379 TGREPGISILE-DGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV---------H 427
Query: 3369 IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+PPV+ KE + + + CEV G P P + W +D ++V
Sbjct: 428 VPPVI------KDKEQV-----TNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 472
Score = 79.8 bits (188), Expect = 2e-13
Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 41/318 (12%)
Query: 2597 STFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNA 2656
S+ L++R V+ V L C +P++TW ++ + N + K+ L++
Sbjct: 901 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKT 959
Query: 2657 VPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
+ D+ Y+C N G L V+ PS E + + + +T L N + LE
Sbjct: 960 LLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG------KMLNETV-LVSNPVQLE 1012
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C+ G P+P ITW+KD++ + G +L G + I++ D+G Y C A NS
Sbjct: 1013 CKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1069
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
++ F + V+P+ ++ +A V + L+
Sbjct: 1070 ATEL-----FYSLQVHVAPS-ISGSNNMVA-------------------VVVNNPVRLEC 1104
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
E RG P + WL++G V+ +V G LAL+ +++G YTC A +A G
Sbjct: 1105 EARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILALTSAQISDTGRYTCVAVNAAGE 1162
Query: 2894 VDMNAAITVVQPSDLDGK 2911
+ + V P ++ G+
Sbjct: 1163 KQRDIDLRVYVPPNIMGE 1180
Score = 78.6 bits (185), Expect = 4e-13
Identities = 82/367 (22%), Positives = 143/367 (38%), Gaps = 58/367 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P ++ ++ L C VKG P P + W K+G + G + L +K+
Sbjct: 531 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLF--LGDPNVELLDRGQVLHLKNARR 588
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D+GRY C +N GK + +L + ++ + V D
Sbjct: 589 NDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI----------KGGNVTTDIS--------- 629
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V ++L C+ G P P ++WYKDG+ ++ + Q+ L I + D
Sbjct: 630 --VLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSA 685
Query: 3237 VYEVTARNNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEA 3293
Y N +G S H + V I +A PL K + L +
Sbjct: 686 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA-------TPLNKQVVIAHSLTLECKAAG 738
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
PS +TW +DGV ++ + + ++ G+ +L + + D G Y C A++ G
Sbjct: 739 NPSPILTWLKDGVPVKANDN--IRIEAGGK-KLEIMSAQEIDRGQYICVATSVAGEKEIK 795
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+V+V+ +PP + D + FI + + ++C V G P P
Sbjct: 796 YEVDVL---------VPPAIEGGD----ETSYFI-------VMVNNLLELDCHVTGSPPP 835
Query: 3414 DVYWLRD 3420
+ WL+D
Sbjct: 836 TIMWLKD 842
Score = 65.7 bits (153), Expect = 3e-09
Identities = 77/309 (24%), Positives = 118/309 (38%), Gaps = 37/309 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ +EG V L C + P+V W + G L+ DG +L V++ +S E
Sbjct: 62 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGE 119
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y CT N G L VY P + + + + LA E+ L C ++ P
Sbjct: 120 YVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV-LAGEEVTLPCEVKSLP 178
Query: 2722 LPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P ITW K+ + I P R+ +L G + I DSG Y C A
Sbjct: 179 PPIITWAKETQLISPFSPRHT--FLPSG--SMKITETRTSDSGMYLCVA----------- 223
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+N G NV A K + R P +V G + + +G P
Sbjct: 224 -INIAG-------NVTQAVKLNVHVPPKIQRGP------KHLKVQVGQRVDIPCNAQGTP 269
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
V +G S V V G TL++ T +++G+YTC A + G + +
Sbjct: 270 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 327
Query: 2901 TVVQPSDLD 2909
V +P ++
Sbjct: 328 HVQEPPTVE 336
Score = 63.3 bits (147), Expect = 1e-08
Identities = 71/316 (22%), Positives = 130/316 (41%), Gaps = 44/316 (13%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
DG + +E + D EY+C N G + + ++ V+ + PT +
Sbjct: 13 DGSLHIERVQL--QDGGEYTCVASNVAGTNNKTTSVVVH-------VLPTIQHGQQILST 63
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ + L C+ G P P + W K + I S ++ A ADG L + +P E+SG
Sbjct: 64 IEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAG--ADG--SLYVVSPGGEESGE 119
Query: 2765 YTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Y C A N+ + R+ Q++ V + ++ L +P + V
Sbjct: 120 YVCTATNT---------AGYAKRKVQLT--VYVRPRVFGDQRGLSQDKP------VEISV 162
Query: 2825 ARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
G + L E++ P + W +E + ++ + F+ G ++ +++ ++SG+Y
Sbjct: 163 LAGEEVTLPCEVKSLPPPIITWAKETQLISP-FSPRHTFLPSG--SMKITETRTSDSGMY 219
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
C A + GNV + V P + P K + + VG+ ++I QG P P
Sbjct: 220 LCVAINIAGNVTQAVKLNVHVPPKIQRGP--------KHLKVQVGQRVDIPCNAQGTPLP 271
Query: 2944 KAVPERIPGEPCVVDG 2959
+ G +VDG
Sbjct: 272 -VITWSKGGSTMLVDG 286
Score = 60.5 bits (140), Expect = 1e-07
Identities = 76/345 (22%), Positives = 136/345 (39%), Gaps = 47/345 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
++ V + L C + P +TW ++GV + K ++ G LE+++A D
Sbjct: 721 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIEAGGKKLEIMSAQEIDR 778
Query: 2662 AEYSCTVENENGA--ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+Y C + G I ++ V P+ E F + N L L+C + G
Sbjct: 779 GQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYF-------IVMVNNLLELDCHVTG 831
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W KD + + D R L +G +L I ++G Y C A N+ +
Sbjct: 832 SPPPTIMWLKDGQLV--DERDGFKILLNG-RKLVIAQAQVSNTGLYRCMAANTAGDHK-- 886
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
E +V+ +V K+ L R V+ Y+ + LQ G
Sbjct: 887 -------EEFEVTVHVPPTIKS----SGLSER------VVVKYK-----PVALQCIANGI 924
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + WL++ + V N + ++ L ++ ++G YTC A +A G +
Sbjct: 925 PNPSITWLKDDQPVNTAQGNLK--IQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 982
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V +P L+ ++ + +L+S + + + G P P
Sbjct: 983 QLHVHEPPSLEDAGKML----NETVLVS--NPVQLECKAAGNPVP 1021
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 62/365 (16%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L L C +G P+P + W K+G + + + + L I + D
Sbjct: 628 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY---LHIPRAQVSDS 684
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---D 3176
Y+C N G A E+S V+ PP L +
Sbjct: 685 ATYTCHVANVAGTA-----------------------EKSFHVDVYVPPMIEGNLATPLN 721
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
++V + + L C+ G+P P ++W KDG V N + LEI D G
Sbjct: 722 KQVVIAHSLTLECKAAGNPSPILTWLKDG--VPVKANDNIRIEAGGKKLEIMSAQEIDRG 779
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL-HEGDELRISAVVEAYP 3295
Y A + +G + + V P G E Y + + L + V P
Sbjct: 780 QYICVATSVAGEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 833
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ W +DG +L R L ++ +A A V+ + G+Y C A+N G +
Sbjct: 834 PPTIMWLKDG-QLVDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKEEFE 890
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V +PP + S + S+ + KP V ++C G P P +
Sbjct: 891 VTV---------HVPPTIKSSGL--SERVVVKYKP----------VALQCIANGIPNPSI 929
Query: 3416 YWLRD 3420
WL+D
Sbjct: 930 TWLKD 934
Score = 58.0 bits (134), Expect = 6e-07
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 11/166 (6%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
V + V+L C P++TW ++G + + + L G I L + +A SD+ Y+
Sbjct: 1095 VVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYT 1153
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C N G +L+VY +PP ++ L + L C+ P P +
Sbjct: 1154 CVAVNAAGEKQRDIDLRVY-------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 1206
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
TW KD + + +++ L I++ +D+G YTC+A N
Sbjct: 1207 TWLKDGHPLL---KKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 1249
Score = 57.6 bits (133), Expect = 7e-07
Identities = 46/186 (24%), Positives = 71/186 (38%), Gaps = 27/186 (14%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ L C +G P P + W+K+G V + + G LT I D GR
Sbjct: 1094 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT--SAQISDTGR 1151
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +++R ++ PP ++ V
Sbjct: 1152 YTCVAVNAAG-----------------------EKQRDIDLRVYVPPNIMGEEQNVSVLI 1188
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ V L CQ PPP ++W KDG ++ K+ E L+I + D G Y
Sbjct: 1189 SQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCE 1246
Query: 3242 ARNNSG 3247
A N +G
Sbjct: 1247 ATNVAG 1252
Score = 52.4 bits (120), Expect = 3e-05
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 13/166 (7%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD-EQFHTLEIAPTNLDDGGVYEVTA 3242
PVRL C+ G P P ++W KDG V N Q L + + D G Y A
Sbjct: 1099 PVRLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVA 1156
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
N +G D +R YV P G E + + + +A P +TW
Sbjct: 1157 VNAAGEKQR------DIDLRVYVPPNIM-GEEQNVSVLISQAVELLCQSDAIPPPTLTWL 1209
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+DG L ++ +++ + + L + +D G YTC A+N G
Sbjct: 1210 KDGHPLL--KKPGLSISENRSV-LKIEDAQVQDTGRYTCEATNVAG 1252
Score = 52.0 bits (119), Expect = 4e-05
Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ +L + L C P P + W+K+GH + ++ G S+ L I+D + D
Sbjct: 1184 VSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV---LKIEDAQVQDT 1240
Query: 3120 GRYSCEATNTHG 3131
GRY+CEATN G
Sbjct: 1241 GRYTCEATNVAG 1252
Score = 44.0 bits (99), Expect = 0.010
Identities = 50/197 (25%), Positives = 77/197 (39%), Gaps = 24/197 (12%)
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGD 3283
+L I L DGG Y A N +G + +VV +V P G + L + EG
Sbjct: 15 SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHGQQILSTI-EGI 67
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTA 3343
+ + P V W + G L + A + DG L + + ++G Y CTA
Sbjct: 68 PVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTA 124
Query: 3344 SNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVII 3403
+N G A KV++ V + P V + + KP G+ V +
Sbjct: 125 TNTAGYAKR--KVQL------------TVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTL 170
Query: 3404 ECEVVGDPKPDVYWLRD 3420
CEV P P + W ++
Sbjct: 171 PCEVKSLPPPIITWAKE 187
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 96.7 bits (230), Expect = 1e-18
Identities = 99/342 (28%), Positives = 149/342 (43%), Gaps = 53/342 (15%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSA 2662
T E S+ L C P + W ++ VLL N L KY + LI LE N V DS
Sbjct: 1217 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LE--NVVLEDSG 1273
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C N G + + +L V+ + PTFT D +L L C+ G PL
Sbjct: 1274 FYTCVANNAAGEDTHTVSLTVH-------VLPTFTELPGDVSLNKGEQLRLSCKATGIPL 1326
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
PK+TW ++ IP+ F +G L I+ + EDSGTY C AENSV FV
Sbjct: 1327 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV------GFV 1375
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
G P V G+ + + GG L E++G PT
Sbjct: 1376 KAIGFVYVKEPPVFK------------------GDYPSHWIEPLGGNAILNCEVKGDPTP 1417
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
++W R+G + E+ R + G +LA+ ++G YTC A + G V+ + ++T
Sbjct: 1418 TIQWNRKGVDI-EISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 1473
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ P + +P + +I+ G I ++ + GEP+P
Sbjct: 1474 LQSPPIITLEPV--------ETVINAGGKIILNCQATGEPQP 1507
Score = 96.3 bits (229), Expect = 2e-18
Identities = 82/299 (27%), Positives = 121/299 (40%), Gaps = 37/299 (12%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDI 3114
+P + +L GE L C+ G P P + W+K+G + E R+ NG L I
Sbjct: 290 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGA 347
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
D G+Y+C ATN G+ L V T+ R E E M L
Sbjct: 348 LTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTI--------RGNKDEAEK------LMTL 393
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D + + C+ G+PPP+++W K+G + Q + I + D
Sbjct: 394 VDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSD 445
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF--CCGLEPLYKLHEGDELRISAVVE 3292
VY A N +G + H L V + P G E + L +G ++ + +
Sbjct: 446 VAVYTCVASNRAGVDNKHYNLQV------FAPPNMDNSMGTEEITVL-KGSSTSMACITD 498
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P+ + W RDG L A +T+ G + L L T D+G YTC ASNE G S
Sbjct: 499 GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVS 554
Score = 95.1 bits (226), Expect = 4e-18
Identities = 91/340 (26%), Positives = 139/340 (40%), Gaps = 41/340 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG+ V L + P +TWY+NG ++ + + L DG + L + A SD+ +Y C
Sbjct: 111 EGTSVSLEXESNAVPPPVITWYKNGRMITEST-HVEILADGQM-LHIKKAEVSDTGQYVC 168
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPLPKI 2725
N G + +L VY +PP+ R+ N + L C G P P I
Sbjct: 169 RAINVAGRDDKNFHLNVY-------VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTI 221
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W K+ K+I + + L+ G +L I DSG YTC A N Q +F++
Sbjct: 222 AWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI- 279
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVE 2844
QV P+V AE + +D V G + L G PT ++
Sbjct: 280 ----QVPPSVAGAE------------------IPSDVSVLLGENVELVCNANGIPTPLIQ 317
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
WL++G+ + R+ V TL + +++G YTC A + G D + V
Sbjct: 318 WLKDGKPIAS-GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 376
Query: 2905 PSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ G EK ++ V INI R G P P+
Sbjct: 377 TPTIRGNK----DEAEK-LMTLVDTSINIECRATGTPPPQ 411
Score = 93.9 bits (223), Expect = 9e-18
Identities = 95/368 (25%), Positives = 144/368 (39%), Gaps = 58/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L IL ++ L C +G P P + W K+G + R + NGF L I+ ++
Sbjct: 757 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF---LHIQSAHV 813
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D GRY C ATN G TDR R +++ PP +
Sbjct: 814 TDTGRYLCMATNAAG-----------TDR------------RRIDLQVHVPPSIAPGPTN 850
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C+ G P P ++W K+G + D+ +N Y+ +L I ++DD
Sbjct: 851 MTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA 910
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
YE T N +G L V + +A E + L H + +A +PS
Sbjct: 911 TYECTVTNGAGDDKRTVDLTVQ--VPPSIADE---PTDFLVTKHAPAVITCTASGVPFPS 965
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W ++G+RL P L G IE + A AG YTC A N G A +
Sbjct: 966 --IHWTKNGIRLLPRGDGYRILS-SGAIE--ILATQLNHAGRYTCVARNAAGSAHRHVTL 1020
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
V PPV+ +P +P + +++ CE G P P +
Sbjct: 1021 HV---------HEPPVI---------QP----QPSELHVILNNPILLPCEATGTPSPFIT 1058
Query: 3417 WLRDFLKV 3424
W ++ + V
Sbjct: 1059 WQKEGINV 1066
Score = 90.2 bits (214), Expect = 1e-16
Identities = 99/365 (27%), Positives = 140/365 (38%), Gaps = 62/365 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I + L+C G P P + W K+G + E R +G L I + D G
Sbjct: 1128 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQITFVQPGDAGH 1183
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C A N G +ST +L V R EG Y + QA
Sbjct: 1184 YTCMAANVAGSSSTSTKLTVHVP------------PRIRSTEGHYTV-------NENSQA 1224
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P C G P P ++W KD V+ KY E + L + L+D G Y
Sbjct: 1225 ILP----CVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCV 1278
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A N +G + L V +V P F L L++G++LR+S P +TW
Sbjct: 1279 ANNAAGEDTHTVSLTV------HVLPTFT-ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 1331
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ + P+ + +G EL + V+ D+G Y CTA N VG G V V
Sbjct: 1332 TFNN-NIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV--- 1383
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDF 3421
+ PPV + EP+ G I+ CEV GDP P + W R
Sbjct: 1384 ------KEPPVFKGDYPSHWIEPL------------GGNAILNCEVKGDPTPTIQWNRKG 1425
Query: 3422 LKVRI 3426
+ + I
Sbjct: 1426 VDIEI 1430
Score = 87.0 bits (206), Expect = 1e-15
Identities = 90/367 (24%), Positives = 141/367 (38%), Gaps = 64/367 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + ++ L C G P P + W KNGH + + + + + + I ++
Sbjct: 848 PTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SV 906
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD Y C TN G D K R+ ++ PP D
Sbjct: 907 DDTATYECTVTNGAG-------------------DDK----RTVDLTVQVPPSIADEPTD 943
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V P +TC G P P + W K+G ++ R + Y+ +EI T L+ G
Sbjct: 944 FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAIEILATQLNHAG 1001
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE--GDELRISAVVEAY 3294
Y ARN +G+ H L V + P +LH + + +
Sbjct: 1002 RYTCVARNAAGSAHRHVTLHVHEPPVIQPQPS---------ELHVILNNPILLPCEATGT 1052
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
PS +TW ++G+ + S R L G L ++ DAG Y C A N G A G
Sbjct: 1053 PSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAGTAL--G 1107
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+++ ++PPV+ P+ KE + + KP + + CE G P P
Sbjct: 1108 KIKL-------NVQVPPVIS----PHLKEYVIAVDKP----------ITLSCEADGLPPP 1146
Query: 3414 DVYWLRD 3420
D+ W +D
Sbjct: 1147 DITWHKD 1153
Score = 87.0 bits (206), Expect = 1e-15
Identities = 88/356 (24%), Positives = 131/356 (36%), Gaps = 43/356 (12%)
Query: 2997 WVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW----GESSQTSSSIGVGLAGDRPEF 3052
W + GI L D + + T N G ++ S+ V L P
Sbjct: 968 WTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 1027
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ P +L ++ L C G P P + W K G V +G L I
Sbjct: 1028 IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQIS 1084
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+D G Y C A N G A +L V PP +
Sbjct: 1085 RAVREDAGTYMCVAQNPAGTALGKIKLNV-----------------------QVPPVISP 1121
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
L++ + P+ L+C+ G PPP ++W+KDG +V R+ +L+I
Sbjct: 1122 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQITFVQP 1178
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A N +G+ S L V +V P E Y ++E + + V +
Sbjct: 1179 GDAGHYTCMAANVAGSSSTSTKLTV------HVPPRI-RSTEGHYTVNENSQAILPCVAD 1231
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ + W +D V L + T + G EL L V D+G YTC A+N G
Sbjct: 1232 GIPTPAINWKKDNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAG 1284
Score = 83.0 bits (196), Expect = 2e-14
Identities = 81/314 (25%), Positives = 123/314 (39%), Gaps = 37/314 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T ++GS + C + P++ W R+G L G++ L++L A DS +
Sbjct: 484 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-THGMV-LQLLKAETEDSGK 541
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C NE G +S LKV P + + + N L L C G P P
Sbjct: 542 YTCIASNEAGEVSKHFILKVL-----EPPHINGSEEHEEISVIVNNPLELTCIASGIPAP 596
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K+TW KD + +P + Q L G L I ED+G YTC A + D + V
Sbjct: 597 KMTWMKDGRPLPQTDQVQT--LGGGEV-LRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 653
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
V PN+ ++ R D V R + L+ + P V
Sbjct: 654 V-----HVPPNIAGTDEPR------------------DITVLRNRQVTLECKSDAVPPPV 690
Query: 2844 -EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
WLR G + RV + G L +++ ++ YTC A + G +TV
Sbjct: 691 ITWLRNGE---RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 747
Query: 2903 VQPSDLDGKPAVIV 2916
P ++ G P +V
Sbjct: 748 NVPPNIKGGPQSLV 761
Score = 80.2 bits (189), Expect = 1e-13
Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 17/193 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S L + + L+C P +TW+++G + ++ R L G +L++
Sbjct: 1117 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-LSSG--SLQI 1173
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELV 2712
P D+ Y+C N G+ STS L V+ +PP RS + + EN + +
Sbjct: 1174 TFVQPGDAGHYTCMAANVAGSSSTSTKLTVH-------VPPRI-RSTEGHYTVNENSQAI 1225
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L C G P P I W KD+ + + Y A+ L ++N EDSG YTC A N+
Sbjct: 1226 LPCVADGIPTPAINWKKDNVLLAN---LLGKYTAEPYGELILENVVLEDSGFYTCVANNA 1282
Query: 2773 VWTDQITHFVNFT 2785
D TH V+ T
Sbjct: 1283 AGED--THTVSLT 1293
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 42/325 (12%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+KRT+ P + TD + + +TC+ P++ W +NG+ L +
Sbjct: 923 DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGY 982
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L G I E+L + + Y+C N G+ L V+ PP
Sbjct: 983 RILSSGAI--EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE-------PPVIQPQPS 1033
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ + N ++L C G P P ITW K+ + + GR A + G L I ED
Sbjct: 1034 ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVRED 1090
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+GTY C A+N T +N QV P + PH L +
Sbjct: 1091 AGTYMCVAQNPAGTALGKIKLNV-----QVPPVI----------------SPH----LKE 1125
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Y +A I L E G P + W ++GR++ E R RV + G +L ++ V ++
Sbjct: 1126 YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ-RV-LSSG--SLQITFVQPGDA 1181
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQP 2905
G YTC A + G+ + +TV P
Sbjct: 1182 GHYTCMAANVAGSSSTSTKLTVHVP 1206
Score = 77.4 bits (182), Expect = 9e-13
Identities = 86/354 (24%), Positives = 136/354 (38%), Gaps = 63/354 (17%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A +TC+ G P P + W KNG + +G + I ++ GRY+C A
Sbjct: 952 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVAR 1008
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G A + L V PP + + V P+ L
Sbjct: 1009 NAAGSAHRHVTLHV-----------------------HEPPVIQPQPSELHVILNNPILL 1045
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+P P ++W K+G V R + L+I+ +D G Y A+N +G
Sbjct: 1046 PCEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAG 1103
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
L V V P L+ Y + + +S + P +TW++DG
Sbjct: 1104 TALGKIKLNVQ------VPPVISPHLKE-YVIAVDKPITLSCEADGLPPPDITWHKDGRA 1156
Query: 3308 LRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S R+ +++ G +++ V DAG YTC A+N G +STS K+ V
Sbjct: 1157 IVESIRQRVLS---SGSLQITF--VQPGDAGHYTCMAANVAGSSSTSTKLTV-------- 1203
Query: 3367 PRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + S + Y+ E I+ C G P P + W +D
Sbjct: 1204 -HVPPRIRSTEGHYT-------------VNENSQAILPCVADGIPTPAINWKKD 1243
Score = 76.6 bits (180), Expect = 1e-12
Identities = 96/408 (23%), Positives = 159/408 (38%), Gaps = 71/408 (17%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
++ G+ H+ N G SS TS+ + V + P + G + A L C
Sbjct: 1176 VQPGDAGHYTCMAANVAG---SSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC 1228
Query: 3073 SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGK 3132
G P P + W K+ + G+ T++ G L ++++ ++D G Y+C A N G+
Sbjct: 1229 VADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILENVVLEDSGFYTCVANNAAGE 1285
Query: 3133 ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI 3192
+ L V P FT D + +RL+C+
Sbjct: 1286 DTHTVSLTV-----------------------HVLPTFTELPGDVSLNKGEQLRLSCKAT 1322
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G P PK++W + + + H+ L I + +D G Y TA N+ G V
Sbjct: 1323 GIPLPKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 1377
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPS 3311
G V K + +EPL G ++ V+ P+ + W R GV + S
Sbjct: 1378 -IGFVYVKEPPVFKGDYPSHWIEPL-----GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 1431
Query: 3312 RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPP 3371
R + + G LA+ DAG YTC A+NE G V+ + + PP
Sbjct: 1432 HR----IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVERSMSLTLQSPP 1478
Query: 3372 VVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ + EP+ + G +I+ C+ G+P+P + W R
Sbjct: 1479 II-------TLEPV------ETVINAGGKIILNCQATGEPQPTITWSR 1513
Score = 74.1 bits (174), Expect = 8e-12
Identities = 78/345 (22%), Positives = 132/345 (38%), Gaps = 40/345 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+D + + G V+L C+ P + W ++G + + R ++ TL + A+ SD
Sbjct: 292 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 351
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ +Y+C N G NL VY +P L + + +ECR G
Sbjct: 352 TGKYTCVATNPAGEEDRIFNLNVY----VTPTIRGNKDEAEKLMTLVDTSINIECRATGT 407
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
P P+I W K+ +P + LA G + I D YTC A N D H
Sbjct: 408 PPPQINWLKNGLPLPLSSHIR--LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDN-KH 463
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+ + PN+ + T + V +G + + G P
Sbjct: 464 Y----NLQVFAPPNMDNSMGTE------------------EITVLKGSSTSMACITDGTP 501
Query: 2841 T-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ WLR+G+ + +A + V L L +SG YTC A + G V +
Sbjct: 502 APSMAWLRDGQPLG---LDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFI 558
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V++P ++G ++I + V + ++ G P PK
Sbjct: 559 LKVLEPPHING------SEEHEEISVIVNNPLELTCIASGIPAPK 597
Score = 73.3 bits (172), Expect = 1e-11
Identities = 83/343 (24%), Positives = 134/343 (39%), Gaps = 44/343 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T V + + LTC V P ++W +N + KL +V G TL+++ A SD E
Sbjct: 13 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI--KLNTNTLIVPGGRTLQIIRAKVSDGGE 70
Query: 2664 YSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y+C N+ G +L VY PS + ++R+ + LE P
Sbjct: 71 YTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVRE-----GTSVSLEXESNAVP 125
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
P ITW+K+ + I + LADG L I D+G Y C+A N D
Sbjct: 126 PPVITWYKNGRMITESTHVE--ILADGQ-MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 182
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-P 2840
+N V P++ E+ I N +T L + G P
Sbjct: 183 LNV-----YVPPSIEGPEREVIVET--------ISNPVT-----------LTCDATGIPP 218
Query: 2841 TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ WL+ + + E + V + G L ++ ++SG YTC A + G +
Sbjct: 219 PTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFL 277
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ P P+V D+ + +GE++ + G P P
Sbjct: 278 SIQVP------PSVAGAEIPSDVSVLLGENVELVCNANGIPTP 314
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/363 (22%), Positives = 144/363 (39%), Gaps = 58/363 (15%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ +L G + ++ C G P P + W+++G + +A +T +G L + +D
Sbjct: 482 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA-HLTVSTHGM--VLQLLKAETED 538
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y+C A+N G+ S + L V+ + S E E +
Sbjct: 539 SGKYTCIASNEAGEVSKHFILKVLEPPHI---------NGSEEHE------------EIS 577
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V P+ LTC G P PK++W KDG + + + L I+ ++D G Y
Sbjct: 578 VIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRY 635
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSV 3297
A + +G + +R +V P EP + ++ + +A P
Sbjct: 636 TCLASSPAGDDD------KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 689
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+TW R+G RL+ + R + G L + D YTC ASN G+
Sbjct: 690 VITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGK-------- 738
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
T+ I V + P++ + + I +S+ ++EC G P P + W
Sbjct: 739 ------TTREFILTVNVPPNIKGGPQSLVILLNKST--------VLECIAEGVPTPRITW 784
Query: 3418 LRD 3420
+D
Sbjct: 785 RKD 787
Score = 71.7 bits (168), Expect = 4e-11
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D T + +V L C + P +TW RNG L + R +++ G L++ NA D+
Sbjct: 668 DITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDT 725
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A Y+C N G + L V +PP + L VLEC G P
Sbjct: 726 ANYTCVASNIAGKTTREFILTVN-------VPPNIKGGPQSLVILLNKSTVLECIAEGVP 778
Query: 2722 LPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P+ITW KD + + RY L +G L I + D+G Y C A N+ TD+
Sbjct: 779 TPRITWRKDGAVLAGNHARYS--ILENGF--LHIQSAHVTDTGRYLCMATNAAGTDR 831
Score = 69.3 bits (162), Expect = 2e-10
Identities = 51/207 (24%), Positives = 84/207 (40%), Gaps = 14/207 (6%)
Query: 2566 MRHRSKAFSEARSVI-SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+ H + AR+ S R ++ + PV ++ + + + L C + P
Sbjct: 997 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 1056
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
+TW + G+ ++ + L G L++ AV D+ Y C +N G L V
Sbjct: 1057 ITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 1114
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+PP + +++ + + L C G P P ITW KD + I R +
Sbjct: 1115 -------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV-- 1165
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L+ G L I P D+G YTC A N
Sbjct: 1166 LSSG--SLQITFVQPGDAGHYTCMAAN 1190
Score = 68.9 bits (161), Expect = 3e-10
Identities = 78/347 (22%), Positives = 137/347 (39%), Gaps = 37/347 (10%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
++ ++ LTC G P P + WMK+G + + T G L I ++D
Sbjct: 575 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGGEVLRISTAQVED 631
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
GRY+C A++ G + + ++ + G P+ LR+R+
Sbjct: 632 TGRYTCLASSPAGDD---------------DKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 676
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V L C+ PPP ++W ++GE + R ++ L+I +L D Y
Sbjct: 677 VT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANY 728
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N +G + L V+ V P G + L L + + + E P+
Sbjct: 729 TCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVILLNKSTV-LECIAEGVPTPR 781
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW +DG L + L+ +G + + A VT D G Y C A+N G ++V
Sbjct: 782 ITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQV 838
Query: 3359 -IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
+ P V+++ + E I KP + + G + ++
Sbjct: 839 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVD 885
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLITLEVLNAVPSDSAEYSC 2666
G L C V PT+ W R GV D ++ +R ++L +G +L + V D+ +Y+C
Sbjct: 1402 GGNAILNCEVKGDPTPTIQWNRKGV--DIEISHRIRQLGNG--SLAIYGTVNEDAGDYTC 1457
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
NE G + S +L + PP T +T A +++L C+ G+P P IT
Sbjct: 1458 VATNEAGVVERSMSLTLQS-------PPIITLEPVETVINAGGKIILNCQATGEPQPTIT 1510
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
W + I D R L++ L I + ED+ + C A N
Sbjct: 1511 WSRQGHSISWDDRVNV--LSNN--SLYIADAQKEDTSEFECVARN 1551
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 30/218 (13%)
Query: 3040 SIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMT 3099
+IG + P F P G A L C VKG P P + W + G ++E + R+
Sbjct: 1377 AIGFVYVKEPPVFKGDYPSHWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEI-SHRIR 1435
Query: 3100 SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
NG L I +D G Y+C ATN G VV ERS
Sbjct: 1436 QLGNG---SLAIYGTVNEDAGDYTCVATNEAG---------VV--------------ERS 1469
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ PP T+ + + A + L CQ G P P ++W + G + +D R N +
Sbjct: 1470 MSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN 1529
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
++L IA +D +E ARN G+V ++V
Sbjct: 1530 ---NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 1564
Score = 65.3 bits (152), Expect = 4e-09
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 35/243 (14%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ LTC+V G PPP +SW K+ + + + N TL+I + DGG Y A N
Sbjct: 20 ISLTCEVSGFPPPDLSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 77
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAP---EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+G L V YV P + + + EG + + A P +TW
Sbjct: 78 QAGESKKKFSLTV------YVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVITW 131
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
Y++G + S + + DGQ+ L + D G Y C A N GR + + V
Sbjct: 132 YKNGRMITESTH--VEILADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY-- 186
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDF 3421
+PP + P+ E + + V + C+ G P P + WL++
Sbjct: 187 -------VPPSIEGPEREVIVETI------------SNPVTLTCDATGIPPPTIAWLKNH 227
Query: 3422 LKV 3424
++
Sbjct: 228 KRI 230
Score = 62.9 bits (146), Expect = 2e-08
Identities = 80/363 (22%), Positives = 134/363 (36%), Gaps = 55/363 (15%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L ++ +LTC V G P P + W+KN ++ + L I + D
Sbjct: 12 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR---TLQIIRAKVSDG 68
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G++ L V ++ + D++ L V
Sbjct: 69 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------------------SLSVVNV 109
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ V L + PPP ++WYK+G + D Q L I + D G Y
Sbjct: 110 REGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYV 167
Query: 3240 VTARNNSGA--VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N +G + H + V I PE +E + + + ++ P
Sbjct: 168 CRAINVAGRDDKNFHLNVYVPPSIE---GPEREVIVETI-----SNPVTLTCDATGIPPP 219
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W ++ R+ S + + G +L +A D+G YTC ASN G+A +
Sbjct: 220 TIAWLKNHKRIENSDSLEVRI-LSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 278
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ ++PP V ++P + G+ V + C G P P + W
Sbjct: 279 I---------QVPPSVAGAEIPSDVSVLL-----------GENVELVCNANGIPTPLIQW 318
Query: 3418 LRD 3420
L+D
Sbjct: 319 LKD 321
Score = 61.7 bits (143), Expect = 5e-08
Identities = 79/364 (21%), Positives = 127/364 (34%), Gaps = 52/364 (14%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ + G + +L P P + W KNG + E + +G L IK + D
Sbjct: 107 VNVREGTSVSLEXESNAVPPPVITWYKNGRMITEST-HVEILADGQ--MLHIKKAEVSDT 163
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G+Y C A N G+ L V ++ E ER VE
Sbjct: 164 GQYVCRAINVAGRDDKNFHLNVYVPPSI-EGP-----EREVIVE---------------- 201
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ PV LTC G PPP ++W K+ + + L+IA + D G Y
Sbjct: 202 TISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYT 261
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVG 3298
A N G + L + V P P + G+ + + P+
Sbjct: 262 CIASNMEGKAQKYYFLSIQ------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 315
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ W +DG + + + +G L + T D G YTC A+N G +
Sbjct: 316 IQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN- 373
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
V ++P + +K+ + ++ IEC G P P + WL
Sbjct: 374 -------------VYVTPTIRGNKD-----EAEKLMTLVDTSINIECRATGTPPPQINWL 415
Query: 3419 RDFL 3422
++ L
Sbjct: 416 KNGL 419
Score = 57.2 bits (132), Expect = 1e-06
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD---NKLKYRKKLVDGLITLEVLNAV 2657
T+ T + + L C P++ W +NG LL+ N+ YR L G +L +++
Sbjct: 849 TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR-LLSSG--SLVIISPS 905
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D+A Y CTV N G + +L V +PP+ D V+ C
Sbjct: 906 VDDTATYECTVTNGAGDDKRTVDLTV-------QVPPSIADEPTDFLVTKHAPAVITCTA 958
Query: 2718 RGQPLPKITWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
G P P I W K+ + +P Y+ L+ G + +G YTC A N+
Sbjct: 959 SGVPFPSIHWTKNGIRLLPRGDGYR--ILSSGAIEILATQ--LNHAGRYTCVARNA 1010
Score = 56.4 bits (130), Expect = 2e-06
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 2613 LTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENE 2671
L C P +TW ++G VL N +Y L +G L + +A +D+ Y C N
Sbjct: 770 LECIAEGVPTPRITWRKDGAVLAGNHARY-SILENGF--LHIQSAHVTDTGRYLCMATNA 826
Query: 2672 NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDD 2731
G +L+V+ +PP+ + + + L C G P P I W K+
Sbjct: 827 AGTDRRRIDLQVH-------VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNG 879
Query: 2732 KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+ D ++ L L I +P+ +D+ TY C N D+ T V+ T QV
Sbjct: 880 HLLNVDQNQNSYRLLSS-GSLVIISPSVDDTATYECTVTNGAGDDKRT--VDLT---VQV 933
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
P++ TD+ V + + G P + W + G
Sbjct: 934 PPSIADEP--------------------TDFLVTKHAPAVITCTASGVPFPSIHWTKNGI 973
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
+ R+ + LA +G YTC A +A G+ + + V +P +
Sbjct: 974 RLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQP 1030
Query: 2911 KPA---VIVGRP 2919
+P+ VI+ P
Sbjct: 1031 QPSELHVILNNP 1042
Score = 56.0 bits (129), Expect = 2e-06
Identities = 48/179 (26%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D + +G +++L+C P +TW N +N + V+G L +
Sbjct: 1298 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN----NNIIPAHFDSVNGHSELVI 1353
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELV 2712
DS Y CT EN G + + V PP F + +
Sbjct: 1354 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE-------PPVFKGDYPSHWIEPLGGNAI 1406
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
L C ++G P P I W + I R + L +G LAI ED+G YTC A N
Sbjct: 1407 LNCEVKGDPTPTIQWNRKGVDIEISHRIR--QLGNG--SLAIYGTVNEDAGDYTCVATN 1461
Score = 45.6 bits (103), Expect = 0.003
Identities = 63/293 (21%), Positives = 103/293 (35%), Gaps = 38/293 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + +L L C P P + W++NG + + R+ G L I + ++
Sbjct: 666 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL-QATPRVRILSGG--RYLQINNADL 722
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D Y+C A+N GK + L V ++G P + L
Sbjct: 723 GDTANYTCVASNIAGKTTREFILTV---------------NVPPNIKGG-PQSLVILLNK 766
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W KDG + + R + F L I ++ D G
Sbjct: 767 STV-------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTG 817
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y A N +G L V +V P G + + + ++ P
Sbjct: 818 RYLCMATNAAGTDRRRIDLQV------HVPPSIAPGPTNMTVI-VNVQTTLACEATGIPK 870
Query: 3297 VGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W ++G L + L G L + + + D Y CT +N G
Sbjct: 871 PSINWRKNGHLLNVDQNQNSYRLLSSG--SLVIISPSVDDTATYECTVTNGAG 921
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKY 2640
+R++S P+ + + G ++ L C PT+TW R G + D+++
Sbjct: 1467 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN- 1525
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAI 2675
V +L + +A D++E+ C N G++
Sbjct: 1526 ----VLSNNSLYIADAQKEDTSEFECVARNLMGSV 1556
>AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein.
Length = 659
Score = 95.9 bits (228), Expect = 2e-18
Identities = 103/357 (28%), Positives = 153/357 (42%), Gaps = 53/357 (14%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SSS + LAG P V GQL L+CS P W K+G + + R
Sbjct: 285 SSSYRISLAGVEPSLVQAALGQL-------VRLSCSDDTAPESQAAWQKDGQPISSDRHR 337
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR- 3156
+ QF+G L I + +D G YSC +T G+ S +L ++ ++A+L R
Sbjct: 338 L--QFDG---SLIIHPLQAEDAGTYSCGSTRP-GRDSQKIQLRIIGGDMAVLSEAELSRF 391
Query: 3157 ------------ERSAEVEGDYP---PQFTMRLR----DRRVQATYP---VRLTCQVIGS 3194
+A G P PQ RLR RV P +R+TC+ G
Sbjct: 392 PQPRDPAQDFGQAGAAGPLGAIPSSHPQPANRLRLDQNQPRVVDASPGQRIRMTCRAEGF 451
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
PPP + W +DG+ V R++ Q + +L I+ ++DGG Y A N
Sbjct: 452 PPPAIEWQRDGQPV--SSPRHQLQPD--GSLVISRVAVEDGGFYTCVAFNGQDR------ 501
Query: 3255 LVVDKGIRAYVAPEF-CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRR 3313
+ ++ V E GL P + EGD R+ VV A SV + W R+G+ ++
Sbjct: 502 --DQRWVQLRVLGELTISGLPPTVTVPEGDTARLLCVV-AGESVNIRWSRNGLPVQADGH 558
Query: 3314 AIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+ DG L + + RD G YTC+A S S +V+V+ T++PR P
Sbjct: 559 RVHQ-SPDG--TLLIYNLRARDEGSYTCSAYQGSQAVSRSTEVKVVSPAPTAQPRDP 612
Score = 51.6 bits (118), Expect = 5e-05
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 17/166 (10%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAE 2663
A G R+++TC P + W R+G + + R +L DG +L + D
Sbjct: 436 ASPGQRIRMTCRAEGFPPPAIEWQRDGQPVSSP---RHQLQPDG--SLVISRVAVEDGGF 490
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C N L+V S +PPT T DT L C + G+ +
Sbjct: 491 YTCVAFNGQDRDQRWVQLRVLGELTISGLPPTVTVPEGDTARLL-------CVVAGESV- 542
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
I W ++ + +DG ++ DG L I N D G+YTC A
Sbjct: 543 NIRWSRNGLPVQADG-HRVHQSPDGT--LLIYNLRARDEGSYTCSA 585
Score = 44.8 bits (101), Expect = 0.006
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 7/96 (7%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R++ E +P + W RDG + R L DG L ++ V D G YTC
Sbjct: 439 GQRIRMTCRAEGFPPPAIEWQRDGQPVSSPRH---QLQPDG--SLVISRVAVEDGGFYTC 493
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
A N R ++ V+G + + +PP V P+
Sbjct: 494 VAFNGQDRDQRWVQLRVLG--ELTISGLPPTVTVPE 527
Score = 44.4 bits (100), Expect = 0.007
Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG +L C V++ + W RNG+ + + DG TL + N D
Sbjct: 524 TVPEGDTARLLC-VVAGESVNIRWSRNGLPVQADGHRVHQSPDG--TLLIYNLRARDEGS 580
Query: 2664 YSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
Y+C+ + A+S S +KV P+ A P P R D LA +L+L+ ++ G
Sbjct: 581 YTCSAYQGSQAVSRSTEVKVVSPAPTAQPRDP--GRDCVDQPELANCDLILQAQLCG 635
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE 3093
SS + + L ++P VD PGQ +TC +G P P + W ++G V
Sbjct: 415 SSHPQPANRLRLDQNQPRVVDASPGQ-------RIRMTCRAEGFPPPAIEWQRDGQPVSS 467
Query: 3094 EAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
++ D L I + ++D G Y+C A N + + +L V+ + T+
Sbjct: 468 PRHQLQP-----DGSLVISRVAVEDGGFYTCVAFNGQDRDQRWVQLRVLGELTI 516
Score = 36.7 bits (81), Expect = 1.5
Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ CR G P P I W +D + + S R+Q DG L I ED G YTC A N
Sbjct: 444 MTCRAEGFPPPAIEWQRDGQPVSSP-RHQL--QPDG--SLVISRVAVEDGGFYTCVAFNG 498
Query: 2773 VWTDQ 2777
DQ
Sbjct: 499 QDRDQ 503
Score = 35.9 bits (79), Expect = 2.6
Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 8/105 (7%)
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
P +EW R+G+ V+ + G +L +S V + G YTC A++
Sbjct: 453 PPAIEWQRDGQPVSSPRHQLQ---PDG--SLVISRVAVEDGGFYTCVAFNGQDRDQRWVQ 507
Query: 2900 ITVVQPSDLDGKPAVIV---GRPEKDILISVGEDINISFRTQGEP 2941
+ V+ + G P + G + + + GE +NI + G P
Sbjct: 508 LRVLGELTISGLPPTVTVPEGDTARLLCVVAGESVNIRWSRNGLP 552
>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
preferentially expressed protein protein.
Length = 3094
Score = 95.5 bits (227), Expect = 3e-18
Identities = 66/216 (30%), Positives = 89/216 (41%), Gaps = 10/216 (4%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F +L +++L G A C + G P P V W G +EE Q G L
Sbjct: 935 PLFTRLLE-DVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHS-L 992
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA-DAKLKRERS-------AE 3161
I + +DEG Y+ A NTHG+A A+L V RT +KL++ S E
Sbjct: 993 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGE 1052
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
+E P F L+D V L CQV G P P +SW+ +G + R Q
Sbjct: 1053 LERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD 1112
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
H L GVY+ N G +C+ L V
Sbjct: 1113 VHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1148
Score = 86.2 bits (204), Expect = 2e-15
Identities = 81/333 (24%), Positives = 132/333 (39%), Gaps = 28/333 (8%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN-GVLLDNKLKYR 2641
+R+ S P F L D++ EG V ++ V P V+W RN + ++ ++
Sbjct: 729 RRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFA 788
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
++ GL L +L A D+ Y+C NE GA A L+V E+ + ++
Sbjct: 789 EEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSL--AVLAPLQ 846
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
D A + EC + G ++ W + + + C+L + + +D
Sbjct: 847 DVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDD 906
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
SG YTCK S D++T T R S P F +L D
Sbjct: 907 SGVYTCKL--STAKDELTCSARLTVRPSLA---------------------PLFTRLLED 943
Query: 2822 YQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
+V G +I G P V W G + E N R+ + GL++L ++ V +
Sbjct: 944 VEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEE-SENLRLRQDGGLHSLHIAHVGSEDE 1002
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPA 2913
GLY A + HG +A + V +P P+
Sbjct: 1003 GLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPS 1035
Score = 85.8 bits (203), Expect = 2e-15
Identities = 82/312 (26%), Positives = 120/312 (38%), Gaps = 46/312 (14%)
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AGE A C V G V W+ G ++ + F+G C L + ++ DD G Y+
Sbjct: 852 AGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYT 911
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C+ + + + ARL V P FT L D V
Sbjct: 912 CKLSTAKDELTCSARLT---------------------VRPSLAPLFTRLLEDVEVLEGR 950
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
R C++ G+PPP V+W G + + QD H+L IA +D G+Y V+A
Sbjct: 951 AARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAV 1010
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCG----------------------LEPLYKLHE 3281
N G C L V++ A P L PL L
Sbjct: 1011 NTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEV 1070
Query: 3282 G--DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G E + V P ++W+ +G R++ S MT RD L AV + AGVY
Sbjct: 1071 GLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLVFPAVGPQHAGVY 1129
Query: 3340 TCTASNEVGRAS 3351
+N++G+A+
Sbjct: 1130 KSVIANKLGKAA 1141
Score = 83.4 bits (197), Expect = 1e-14
Identities = 94/367 (25%), Positives = 139/367 (37%), Gaps = 36/367 (9%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+ ++ V+G+P P V W++N V + R + G C L I D G Y+C
Sbjct: 754 GQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTC 813
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+A N +G ARL V RS V L+D V A
Sbjct: 814 KAVNEYGARQCEARLEVRAH----------PESRSLAVLAP--------LQDVDVGAGEM 855
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ-DEQFHTLEIAPTNLDDGGVYEVTAR 3243
C V G +V W G + + K D + L + + DD GVY
Sbjct: 856 ALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLS 915
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
++C L V R +AP F LE + L EG R + P VTW
Sbjct: 916 TAKDELTCSARLTV----RPSLAPLFTRLLEDVEVL-EGRAARFDCKISGTPPPVVTWTH 970
Query: 3304 DGVRLRPSRRAIMTLDRDGQIE-LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
G + S + L +DG + L +A V + D G+Y +A N G+A S ++ V
Sbjct: 971 FGCPMEESEN--LRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPR 1028
Query: 3363 QTSEPRIPPVVISPDVPYSKE---------PMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ + P +P E P F+R + E ++EC+V G P P
Sbjct: 1029 TAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYP 1088
Query: 3414 DVYWLRD 3420
+ W +
Sbjct: 1089 TISWFHN 1095
Score = 74.9 bits (176), Expect = 5e-12
Identities = 74/266 (27%), Positives = 107/266 (40%), Gaps = 27/266 (10%)
Query: 3155 KRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR 3214
+ RS++ PP F + L D+ V+ V ++ +V G P P VSW ++ + V D+RR
Sbjct: 727 QNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRR 786
Query: 3215 NKYQDE-QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
+ E L I D G Y A N GA C L V RA+ L
Sbjct: 787 FAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV----RAHPESRSLAVL 842
Query: 3274 EPLYKLHEG-DELRISAVVEAYPS-VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
PL + G E+ + + A P+ V V W G L+P+ + +L L +V
Sbjct: 843 APLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSV 902
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
D+GVYTC S + S ++ T P S P+F R
Sbjct: 903 HEDDSGVYTCKLSTAKDELTCSARL-------TVRP-------------SLAPLFTRLLE 942
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYW 3417
E EG +C++ G P P V W
Sbjct: 943 DVEVLEGRAARFDCKISGTPPPVVTW 968
Score = 74.5 bits (175), Expect = 6e-12
Identities = 69/256 (26%), Positives = 110/256 (42%), Gaps = 29/256 (11%)
Query: 2690 SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV 2749
S PPTF S+ D ++++ R++G+P P ++W ++ + + D R A G+
Sbjct: 736 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGL 795
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
CRL I D+G YTCKA N + R+ + V ++R SL
Sbjct: 796 CRLRILAAERGDAGFYTCKAVNE-----------YGARQCEARLEVRAHPESR----SLA 840
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE--WLREGRSVTEVYRNARVFVEQGL 2867
P L D V G + + G PT VE WL GR + ++ +
Sbjct: 841 VLAP-----LQDVDVGAGEMALFECLVAG-PTDVEVDWLCRGRLLQPALLKCKMHFDGRK 894
Query: 2868 YTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISV 2927
L L+ V E +SG+YTC+ +A + +A +T V+PS A + R +D+ +
Sbjct: 895 CKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLT-VRPS-----LAPLFTRLLEDVEVLE 948
Query: 2928 GEDINISFRTQGEPKP 2943
G + G P P
Sbjct: 949 GRAARFDCKISGTPPP 964
Score = 71.3 bits (167), Expect = 6e-11
Identities = 88/323 (27%), Positives = 132/323 (40%), Gaps = 40/323 (12%)
Query: 2946 VPERIPGEPCVVDGGNNWVSLAW--PKSDPQTTAP-VLAYKVESWLIGAEGGARWVELGI 3002
VP G P VV V+L W P+S P L Y V+ ++G++ +W L +
Sbjct: 1152 VPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSD---QWTAL-V 1207
Query: 3003 TPLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAG----DRPEFVDIL 3056
T L + A L++G ++ FRV + S S + + G + P +D
Sbjct: 1208 TGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLD-K 1266
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMT-SQFNGFDCCLTIKDI 3114
P + ++ G+ A++T + VVW G +E AG SQ + CL I +
Sbjct: 1267 PDIVYVVEGQPASVTVTFNHVEAQ-VVWRSCRGALLEARAGVYELSQPDDDQYCLRICRV 1325
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+ D G +C A N HG + L + A+A P+F +
Sbjct: 1326 SRRDMGALTCTARNRHGTQTCSVTLEL--------AEA---------------PRFESIM 1362
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D V A R V G P P + WYKD + + +E +L + T D
Sbjct: 1363 EDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQD 1422
Query: 3235 GGVYEVTARNNSGAVSCHCGLVV 3257
GGVY TA+N +G VSC L V
Sbjct: 1423 GGVYTCTAQNLAGEVSCKAELAV 1445
Score = 64.1 bits (149), Expect = 8e-09
Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 8/128 (6%)
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVV 3083
T RNR+G +QT S + + LA + P F I+ +++ AGETA V+GKP+P ++
Sbjct: 1336 TARNRHG----TQTCS-VTLELA-EAPRFESIME-DVEVGAGETARFAVVVEGKPLPDIM 1388
Query: 3084 WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
W K+ + E+ ++ + +C L + D G Y+C A N G+ S A LAV +
Sbjct: 1389 WYKD-EVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 1447
Query: 3144 DRTVWEAD 3151
+T E +
Sbjct: 1448 AQTAMEVE 1455
Score = 63.3 bits (147), Expect = 1e-08
Identities = 56/225 (24%), Positives = 89/225 (39%), Gaps = 27/225 (12%)
Query: 2574 SEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
S A+ ++ L+ + P+F+ L D +EG + C + + P VTW G
Sbjct: 915 STAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCP 974
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--------P 2685
++ R + GL +L + + D Y+ + N +G SA L V P
Sbjct: 975 MEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP 1034
Query: 2686 SFEASPIP----------------PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFK 2729
S + +P P F R ++D E +LEC++ G P P I+WF
Sbjct: 1035 SSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFH 1094
Query: 2730 DDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ +I SD R Y V RL P+ +G Y N +
Sbjct: 1095 NGHRIQSSDDRRMTQY--RDVHRLVFPAVGPQHAGVYKSVIANKL 1137
Score = 62.1 bits (144), Expect = 3e-08
Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Query: 3219 DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
D+ + L I + D G TARN G +C L + + AP F +E + +
Sbjct: 1314 DDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAE------APRFESIMEDV-E 1366
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ G+ R + VVE P + WY+D V L S + + + L + + +D GV
Sbjct: 1367 VGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE-ENECSLVVLSTGAQDGGV 1425
Query: 3339 YTCTASNEVGRASTSGKVEV 3358
YTCTA N G S ++ V
Sbjct: 1426 YTCTAQNLAGEVSCKAELAV 1445
Score = 56.8 bits (131), Expect = 1e-06
Identities = 31/93 (33%), Positives = 44/93 (47%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P F + L++ V V L C + +PPP+VSW+KDG + + R + + HTL +
Sbjct: 593 PVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLL 652
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKG 3260
D G Y TA N G +C L V G
Sbjct: 653 REARAADAGSYMATATNELGQATCAASLTVRPG 685
Score = 54.8 bits (126), Expect = 5e-06
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 34/201 (16%)
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIM 3316
V G AP F L+ + + G ++ + ++ A P V+W++DG LR R ++
Sbjct: 583 VSAGEEPLEAPVFEIPLQNVV-VAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLL 641
Query: 3317 TLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE---------- 3366
+ + L L DAG Y TA+NE+G+A+ + + V TS
Sbjct: 642 RAEGERHT-LLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEE 700
Query: 3367 ---------------PRIPPVVISP-------DVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
PR P + SP D P F REG VI+
Sbjct: 701 YLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMS 760
Query: 3405 CEVVGDPKPDVYWLRDFLKVR 3425
V G+PKP V WLR+ VR
Sbjct: 761 IRVQGEPKPVVSWLRNRQPVR 781
Score = 50.8 bits (116), Expect = 8e-05
Identities = 31/126 (24%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
D L + D +CT N +G + S L++ + P F + D
Sbjct: 1315 DDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-------PRFESIMEDVEV 1367
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
A + G+PLP I W+KD+ + ++ + +F + C L + + +D G Y
Sbjct: 1368 GAGETARFAVVVEGKPLPDIMWYKDEVLL-TESSHVSFVYEENECSLVVLSTGAQDGGVY 1426
Query: 2766 TCKAEN 2771
TC A+N
Sbjct: 1427 TCTAQN 1432
Score = 49.2 bits (112), Expect = 3e-04
Identities = 29/104 (27%), Positives = 48/104 (46%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PVF L + G+ V L C + ++ P V+W+++G L ++ + + TL +
Sbjct: 593 PVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLL 652
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT 2697
A +D+ Y T NE G + +A+L V P SP T
Sbjct: 653 REARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPIT 696
Score = 47.2 bits (107), Expect = 0.001
Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
L EG+ + + A P+ ++W +D LR I+ +DG+ L++ R AG+
Sbjct: 2466 LLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGL 2525
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV--PYSKEPMFIRKPRSSEA 3395
Y C+A+N +G ++S V V R+P + P+V Y + + KP S A
Sbjct: 2526 YECSATNVLGSITSSCTVAV--------ARVPGKLAPPEVTQTYQDTALVLWKPGDSRA 2576
Score = 46.0 bits (104), Expect = 0.002
Identities = 66/278 (23%), Positives = 107/278 (38%), Gaps = 37/278 (13%)
Query: 2684 YPSFEASPIP-PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA 2742
Y S P+ P F +++ +++L+C I P P+++W KD + S+GR
Sbjct: 582 YVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRL-- 639
Query: 2743 FYLADGVCR-LAIDNPTPEDSGTY-----------TCKAENSVWTDQITHFVN--FTGRE 2788
A+G L + D+G+Y TC A +V T + T E
Sbjct: 640 LLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDE 699
Query: 2789 SQVSPNVVTAE------KTRIARQSLESRR----------PHFGNVLTDYQVARGGTIGL 2832
+SP E +T + S R P F L D V G + +
Sbjct: 700 EYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIM 759
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ ++G P V WLR + V R E GL L + ++G YTC+A + +
Sbjct: 760 SIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEY 819
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
G A + V + ++ V P +D+ + GE
Sbjct: 820 GARQCEARLEVRAHPE---SRSLAVLAPLQDVDVGAGE 854
Score = 44.4 bits (100), Expect = 0.007
Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 3046 AGDRPEFVDI--LPGQLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
AG+ P + +P Q ++A G L C + P P V W K+G + E GR+ +
Sbjct: 585 AGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSE-GRLLLRA 643
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
G L +++ D G Y ATN G+A+ A L V
Sbjct: 644 EGERHTLLLREARAADAGSYMATATNELGQATCAASLTV 682
Score = 42.7 bits (96), Expect = 0.022
Identities = 25/82 (30%), Positives = 32/82 (39%)
Query: 2690 SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV 2749
S PP F ++D L L C P P I+W KD K + S+ DG
Sbjct: 2451 SDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGR 2510
Query: 2750 CRLAIDNPTPEDSGTYTCKAEN 2771
L+I +G Y C A N
Sbjct: 2511 QLLSIPRAGKRHAGLYECSATN 2532
Score = 42.3 bits (95), Expect = 0.030
Identities = 25/99 (25%), Positives = 40/99 (40%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F + + D G + V P + WY++ VLL + +L V
Sbjct: 1356 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVV 1415
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPI 2692
L+ D Y+CT +N G +S A L V+ + A +
Sbjct: 1416 LSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEV 1454
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ-DEQ 3221
E D+PP F ++L+D+ + L C P P +SW KD + + + +
Sbjct: 2450 ESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDG 2509
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPE 3268
L I G+YE +A N G+++ C + V + PE
Sbjct: 2510 RQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPE 2556
Score = 40.3 bits (90), Expect = 0.12
Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 2801 TRIARQSLE-SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRN 2858
T+ +LE + P F +++ D +V G T V + G P + W ++ +TE
Sbjct: 1343 TQTCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHV 1402
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ V+ E + LS + + G+YTC A + G V A + V
Sbjct: 1403 SFVYEENECSLVVLSTGAQ-DGGVYTCTAQNLAGEVSCKAELAV 1445
Score = 39.5 bits (88), Expect = 0.21
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 3/111 (2%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLK---ILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
S+ +G +F + +LK +L GE A L C P P + WMK+
Sbjct: 2435 SASVQEELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKS 2494
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ E + L+I G Y C ATN G ++ +AV
Sbjct: 2495 LRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 2545
Score = 39.1 bits (87), Expect = 0.28
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK-YRKKLVDGLITLE 2652
PVF L D+ +EG L C + P ++W ++ L ++ DG L
Sbjct: 2455 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2514
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT 2703
+ A + Y C+ N G+I++S + V PP T++ +DT
Sbjct: 2515 IPRAGKRHAGLYECSATNVLGSITSSCTVAV-ARVPGKLAPPEVTQTYQDT 2564
>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
Length = 2242
Score = 95.5 bits (227), Expect = 3e-18
Identities = 66/216 (30%), Positives = 89/216 (41%), Gaps = 10/216 (4%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F +L +++L G A C + G P P V W G +EE Q G L
Sbjct: 83 PLFTRLLE-DVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHS-L 140
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA-DAKLKRERS-------AE 3161
I + +DEG Y+ A NTHG+A A+L V RT +KL++ S E
Sbjct: 141 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGE 200
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
+E P F L+D V L CQV G P P +SW+ +G + R Q
Sbjct: 201 LERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD 260
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
H L GVY+ N G +C+ L V
Sbjct: 261 VHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 296
Score = 84.2 bits (199), Expect = 7e-15
Identities = 81/311 (26%), Positives = 119/311 (38%), Gaps = 46/311 (14%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE A C V G V W+ G ++ + F+G C L + ++ DD G Y+C
Sbjct: 1 GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 60
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+ + + + ARL V P FT L D V
Sbjct: 61 KLSTAKDELTCSARLTV---------------------RPSLAPLFTRLLEDVEVLEGRA 99
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
R C++ G+PPP V+W G + + QD H+L IA +D G+Y V+A N
Sbjct: 100 ARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVN 159
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCG----------------------LEPLYKLHEG 3282
G C L V++ A P L PL L G
Sbjct: 160 THGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVG 219
Query: 3283 --DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
E + V P ++W+ +G R++ S MT RD L AV + AGVY
Sbjct: 220 LAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLVFPAVGPQHAGVYK 278
Query: 3341 CTASNEVGRAS 3351
+N++G+A+
Sbjct: 279 SVIANKLGKAA 289
Score = 71.3 bits (167), Expect = 6e-11
Identities = 88/323 (27%), Positives = 132/323 (40%), Gaps = 40/323 (12%)
Query: 2946 VPERIPGEPCVVDGGNNWVSLAW--PKSDPQTTAP-VLAYKVESWLIGAEGGARWVELGI 3002
VP G P VV V+L W P+S P L Y V+ ++G++ +W L +
Sbjct: 300 VPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSD---QWTAL-V 355
Query: 3003 TPLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAG----DRPEFVDIL 3056
T L + A L++G ++ FRV + S S + + G + P +D
Sbjct: 356 TGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLD-K 414
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMT-SQFNGFDCCLTIKDI 3114
P + ++ G+ A++T + VVW G +E AG SQ + CL I +
Sbjct: 415 PDIVYVVEGQPASVTVTFNHVEAQ-VVWRSCRGALLEARAGVYELSQPDDDQYCLRICRV 473
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+ D G +C A N HG + L + A+A P+F +
Sbjct: 474 SRRDMGALTCTARNRHGTQTCSVTLEL--------AEA---------------PRFESIM 510
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
D V A R V G P P + WYKD + + +E +L + T D
Sbjct: 511 EDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQD 570
Query: 3235 GGVYEVTARNNSGAVSCHCGLVV 3257
GGVY TA+N +G VSC L V
Sbjct: 571 GGVYTCTAQNLAGEVSCKAELAV 593
Score = 64.1 bits (149), Expect = 8e-09
Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 8/128 (6%)
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVV 3083
T RNR+G +QT S + + LA + P F I+ +++ AGETA V+GKP+P ++
Sbjct: 484 TARNRHG----TQTCS-VTLELA-EAPRFESIME-DVEVGAGETARFAVVVEGKPLPDIM 536
Query: 3084 WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
W K+ + E+ ++ + +C L + D G Y+C A N G+ S A LAV +
Sbjct: 537 WYKD-EVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 595
Query: 3144 DRTVWEAD 3151
+T E +
Sbjct: 596 AQTAMEVE 603
Score = 63.3 bits (147), Expect = 1e-08
Identities = 56/225 (24%), Positives = 89/225 (39%), Gaps = 27/225 (12%)
Query: 2574 SEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL 2633
S A+ ++ L+ + P+F+ L D +EG + C + + P VTW G
Sbjct: 63 STAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCP 122
Query: 2634 LDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--------P 2685
++ R + GL +L + + D Y+ + N +G SA L V P
Sbjct: 123 MEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP 182
Query: 2686 SFEASPIP----------------PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFK 2729
S + +P P F R ++D E +LEC++ G P P I+WF
Sbjct: 183 SSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFH 242
Query: 2730 DDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ +I SD R Y V RL P+ +G Y N +
Sbjct: 243 NGHRIQSSDDRRMTQY--RDVHRLVFPAVGPQHAGVYKSVIANKL 285
Score = 62.1 bits (144), Expect = 3e-08
Identities = 75/322 (23%), Positives = 121/322 (37%), Gaps = 25/322 (7%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV-PSDSAEYSC 2666
G C V +D V W G LL L K DG +L +V DS Y+C
Sbjct: 1 GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 60
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
+ ++ SA L V PS + P FTR + D L +C+I G P P +T
Sbjct: 61 KLSTAKDELTCSARLTVRPS-----LAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVT 115
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS---------VWTDQ 2777
W + + G+ L I + ED G Y A N+ ++ ++
Sbjct: 116 WTHFGCPM-EESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEE 174
Query: 2778 ITHFVNFTGRESQVSPNV-VTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
+ + + P++ E+ + R S+ P F L D +V L+ ++
Sbjct: 175 PRTAASGPSSKLEKMPSIPEEPEQGELERLSI----PDFLRPLQDLEVGLAKEAMLECQV 230
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P + W G + + + R+ + ++ L V +G+Y + G
Sbjct: 231 TGLPYPTISWFHNGHRI-QSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAA 289
Query: 2896 MNA--AITVVQPSDLDGKPAVI 2915
A +T V P DG P V+
Sbjct: 290 CYAHLYVTDVVPGPPDGAPQVV 311
Score = 62.1 bits (144), Expect = 3e-08
Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Query: 3219 DEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
D+ + L I + D G TARN G +C L + + AP F +E + +
Sbjct: 462 DDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAE------APRFESIMEDV-E 514
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ G+ R + VVE P + WY+D V L S + + + L + + +D GV
Sbjct: 515 VGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE-ENECSLVVLSTGAQDGGV 573
Query: 3339 YTCTASNEVGRASTSGKVEV 3358
YTCTA N G S ++ V
Sbjct: 574 YTCTAQNLAGEVSCKAELAV 593
Score = 58.8 bits (136), Expect = 3e-07
Identities = 62/243 (25%), Positives = 94/243 (38%), Gaps = 18/243 (7%)
Query: 3189 CQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ-DEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C V G +V W G + + K D + L + + DD GVY
Sbjct: 8 CLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKD 67
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
++C L V R +AP F LE + L EG R + P VTW G
Sbjct: 68 ELTCSARLTV----RPSLAPLFTRLLEDVEVL-EGRAARFDCKISGTPPPVVTWTHFGCP 122
Query: 3308 LRPSRRAIMTLDRDGQIE-LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
+ S + L +DG + L +A V + D G+Y +A N G+A S ++ V +
Sbjct: 123 MEESEN--LRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAAS 180
Query: 3367 PRIPPVVISPDVPYSKE---------PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+ P +P E P F+R + E ++EC+V G P P + W
Sbjct: 181 GPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISW 240
Query: 3418 LRD 3420
+
Sbjct: 241 FHN 243
Score = 50.8 bits (116), Expect = 8e-05
Identities = 31/126 (24%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
D L + D +CT N +G + S L++ + P F + D
Sbjct: 463 DDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-------PRFESIMEDVEV 515
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
A + G+PLP I W+KD+ + ++ + +F + C L + + +D G Y
Sbjct: 516 GAGETARFAVVVEGKPLPDIMWYKDEVLL-TESSHVSFVYEENECSLVVLSTGAQDGGVY 574
Query: 2766 TCKAEN 2771
TC A+N
Sbjct: 575 TCTAQN 580
Score = 47.2 bits (107), Expect = 0.001
Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
L EG+ + + A P+ ++W +D LR I+ +DG+ L++ R AG+
Sbjct: 1614 LLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGL 1673
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV--PYSKEPMFIRKPRSSEA 3395
Y C+A+N +G ++S V V R+P + P+V Y + + KP S A
Sbjct: 1674 YECSATNVLGSITSSCTVAV--------ARVPGKLAPPEVTQTYQDTALVLWKPGDSRA 1724
Score = 42.7 bits (96), Expect = 0.022
Identities = 25/82 (30%), Positives = 32/82 (39%)
Query: 2690 SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV 2749
S PP F ++D L L C P P I+W KD K + S+ DG
Sbjct: 1599 SDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGR 1658
Query: 2750 CRLAIDNPTPEDSGTYTCKAEN 2771
L+I +G Y C A N
Sbjct: 1659 QLLSIPRAGKRHAGLYECSATN 1680
Score = 42.3 bits (95), Expect = 0.030
Identities = 25/99 (25%), Positives = 40/99 (40%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F + + D G + V P + WY++ VLL + +L V
Sbjct: 504 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVV 563
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPI 2692
L+ D Y+CT +N G +S A L V+ + A +
Sbjct: 564 LSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEV 602
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ-DEQ 3221
E D+PP F ++L+D+ + L C P P +SW KD + + + +
Sbjct: 1598 ESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDG 1657
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPE 3268
L I G+YE +A N G+++ C + V + PE
Sbjct: 1658 RQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPE 1704
Score = 40.3 bits (90), Expect = 0.12
Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 2801 TRIARQSLE-SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRN 2858
T+ +LE + P F +++ D +V G T V + G P + W ++ +TE
Sbjct: 491 TQTCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHV 550
Query: 2859 ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ V+ E + LS + + G+YTC A + G V A + V
Sbjct: 551 SFVYEENECSLVVLSTGAQ-DGGVYTCTAQNLAGEVSCKAELAV 593
Score = 39.5 bits (88), Expect = 0.21
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 3/111 (2%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLK---ILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
S+ +G +F + +LK +L GE A L C P P + WMK+
Sbjct: 1583 SASVQEELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKS 1642
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ E + L+I G Y C ATN G ++ +AV
Sbjct: 1643 LRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 1693
Score = 39.1 bits (87), Expect = 0.28
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK-YRKKLVDGLITLE 2652
PVF L D+ +EG L C + P ++W ++ L ++ DG L
Sbjct: 1603 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 1662
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT 2703
+ A + Y C+ N G+I++S + V PP T++ +DT
Sbjct: 1663 IPRAGKRHAGLYECSATNVLGSITSSCTVAV-ARVPGKLAPPEVTQTYQDT 1712
Score = 38.3 bits (85), Expect = 0.48
Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 6/101 (5%)
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+WL GR + ++ + L L+ V E +SG+YTC+ +A + +A +T
Sbjct: 18 VDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLT- 76
Query: 2903 VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V+PS A + R +D+ + G + G P P
Sbjct: 77 VRPS-----LAPLFTRLLEDVEVLEGRAARFDCKISGTPPP 112
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 95.1 bits (226), Expect = 4e-18
Identities = 103/392 (26%), Positives = 154/392 (39%), Gaps = 55/392 (14%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-- 3090
E S+ I + + G P+ + LP + + G +A L C G+P P V W + +
Sbjct: 33 ELGDASAEIQLAV-GHAPQLTE-LPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL 90
Query: 3091 -VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE 3149
+ AGR + L + + +D+ Y CEA N GK ARL V
Sbjct: 91 GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVT------- 143
Query: 3150 ADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVI-GSPPPKVSWYKDGEEV 3208
G PPQ RV PV L C V+ G P P+ W KDG +
Sbjct: 144 --------------GHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPL 189
Query: 3209 VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPE 3268
R + D H L+ A + G Y A N +G+ LVV R +
Sbjct: 190 PPGSRHSIRADGSLH-LDRALQ--EHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTAT 246
Query: 3269 FCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELAL 3328
+ +EG + V P+ +TW ++ L SR + ++G L +
Sbjct: 247 H-------HITNEGVPASLPCVASGVPAPTITWTKETNALT-SRGPHYNVSKEGT--LLI 296
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
A + +DAG Y CTA+N VG +S ++ V ++PRI +
Sbjct: 297 AQPSAQDAGAYVCTATNTVGFSSQEMRLSV-----NTKPRI----------HMNGSRNAD 341
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P A+ G+ V ++CE G P P V W +D
Sbjct: 342 VPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKD 373
Score = 77.8 bits (183), Expect = 6e-13
Identities = 87/329 (26%), Positives = 127/329 (38%), Gaps = 37/329 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
P+ P +++L G+ +L C V G+P+P W+K+G + R + + +G
Sbjct: 148 PQIASSAP-TVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPP-GSRHSIRADG---S 202
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L + + GRYSC ATNT G + R E+ PP
Sbjct: 203 LHLDRALQEHAGRYSCVATNTAGS-----------------------QHRDVELVVQVPP 239
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+ P L C G P P ++W K+ + R Y + TL IA
Sbjct: 240 RIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALT--SRGPHYNVSKEGTLLIA 297
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
+ D G Y TA N G S L V+ R ++ + G+E+ +
Sbjct: 298 QPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLD 357
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ P VTW +D + P L L LA V D+G Y CTASN G
Sbjct: 358 CEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGS---LRLAQVQVGDSGHYECTASNPAG 414
Query: 3349 RASTSGKVEVIGTDQTS-EPRIPPVVISP 3376
AS + V G +TS +P+ PV P
Sbjct: 415 SASHRYVLGVQG--RTSWQPQSLPVPHHP 441
Score = 60.9 bits (141), Expect = 8e-08
Identities = 54/186 (29%), Positives = 72/186 (38%), Gaps = 18/186 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRN-----GVLLDNKLKYRKKLVD-G 2647
P + D T G L C PTVTW R G+ L R + D G
Sbjct: 49 PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG 108
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
++ E + P D A Y C N G + A L V PP S L
Sbjct: 109 VLFFE--SVAPEDQAPYVCEARNVFGKVQAEARLIV-----TGHAPPQIASSAPTVRVLE 161
Query: 2708 ENELVLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
+ L C + G+PLP+ W KD + +P R+ ADG L +D E +G Y+
Sbjct: 162 GQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHS--IRADG--SLHLDRALQEHAGRYS 217
Query: 2767 CKAENS 2772
C A N+
Sbjct: 218 CVATNT 223
Score = 58.4 bits (135), Expect = 4e-07
Identities = 50/184 (27%), Positives = 67/184 (36%), Gaps = 7/184 (3%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG L C PT+TW + L ++ + +G TL + D+ Y C
Sbjct: 252 EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEG--TLLIAQPSAQDAGAYVC 309
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
T N G S L V A E+ L+C +G P P +T
Sbjct: 310 TATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSPPPLVT 369
Query: 2727 WFKDDKQIPS-DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
W KD + +P RY L G RLA DSG Y C A N + + +
Sbjct: 370 WTKDSRPVPPITNRYG--LLPSGSLRLA--QVQVGDSGHYECTASNPAGSASHRYVLGVQ 425
Query: 2786 GRES 2789
GR S
Sbjct: 426 GRTS 429
Score = 42.7 bits (96), Expect = 0.022
Identities = 39/126 (30%), Positives = 54/126 (42%), Gaps = 14/126 (11%)
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + A D+ Y+C NE G S L V + + + +P R + T L +
Sbjct: 13 LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELP----RDV--TVELGRSA 66
Query: 2711 LVLECRIRGQPLPKITWFKDDKQ----IPSDGRYQAFYLAD-GVCRLAIDNPTPEDSGTY 2765
L L CR G+P P +TW + D Q GR D GV L ++ PED Y
Sbjct: 67 L-LACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGV--LFFESVAPEDQAPY 123
Query: 2766 TCKAEN 2771
C+A N
Sbjct: 124 VCEARN 129
Score = 35.9 bits (79), Expect = 2.6
Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE-PR 3368
+L + A RDAG YTC A NE+G AS ++ V Q +E PR
Sbjct: 12 KLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPR 56
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 93.1 bits (221), Expect = 2e-17
Identities = 101/370 (27%), Positives = 136/370 (36%), Gaps = 62/370 (16%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +A E L C G P P + W K G V G T G L I +
Sbjct: 850 LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA--TGVSTQVLPGGQ--LRIAHAS 905
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+D G Y C A N+ G A RL V PP L
Sbjct: 906 PEDAGNYLCIAKNSAGSAMGKTRLVV-----------------------QVPPVIENGLP 942
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D L C+ GSP P ++W KDG+ V K+ + L + D
Sbjct: 943 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV--SGAEGKFTIQPSGELLVKNLEGQDA 1000
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y TA N G L + V P F L L GD L + P
Sbjct: 1001 GTYTCTAENAVGRARRRVHLTI------LVLPVFTT-LPGDRSLRLGDRLWLRCAARGSP 1053
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+ + W V RP + ++DG L AAV+ D+G Y C A N VGR
Sbjct: 1054 TPRIGWT---VNDRPVTEGVS--EQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSF 1108
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V V + PV+ Y EP+ G ++ ++C V GDP PD+
Sbjct: 1109 VHV---------KEAPVLQGEAFSYLVEPV------------GGSIQLDCVVRGDPVPDI 1147
Query: 3416 YWLRDFLKVR 3425
+W++D L +R
Sbjct: 1148 HWIKDGLPLR 1157
Score = 91.1 bits (216), Expect = 6e-17
Identities = 95/360 (26%), Positives = 140/360 (38%), Gaps = 62/360 (17%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L G A L C +G P P + W K+G V G+ T Q +G L +K++ D
Sbjct: 944 LSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNLEGQDA 1000
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y+C A N G+A L ++ V L +RS +RL DR
Sbjct: 1001 GTYTCTAENAVGRARRRVHLTIL----VLPVFTTLPGDRS------------LRLGDR-- 1042
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
+ L C GSP P++ W + V + + TL+ A + +D G Y
Sbjct: 1043 -----LWLRCAARGSPTPRIGWTVNDRPVT----EGVSEQDGGSTLQRAAVSREDSGTYV 1093
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N G V K F +EP+ G +++ VV P +
Sbjct: 1094 CWAENRVGRTQA-VSFVHVKEAPVLQGEAFSYLVEPV-----GGSIQLDCVVRGDPVPDI 1147
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
W +DG+ LR S + ++G L + DAG Y C A NE+G A
Sbjct: 1148 HWIKDGLPLRGSH--LRHQLQNG--SLTIHRTERDDAGRYQCLAENEMGVAK-------- 1195
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
VVI + P+F +P+ R GD V + C+ G+P P + WL+
Sbjct: 1196 -----------KVVI---LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQ 1241
Score = 82.6 bits (195), Expect = 2e-14
Identities = 85/317 (26%), Positives = 128/317 (40%), Gaps = 37/317 (11%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTA-VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK 2642
RT + P F T+ + V GS + LTC V PTVTW ++ + +++ +
Sbjct: 27 RTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV 86
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
G + L L P+ + Y+C EN + V + P + +
Sbjct: 87 VSRGGRLQLSRLQ--PAQAGTYTCVAENTQAEARKDFVVAVLVA------PRIRSSGVAR 138
Query: 2703 TFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPE 2760
H+ E + V L+C GQP P + W KD + D G + FYL G L +
Sbjct: 139 EHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG--SLVLKGLWAS 196
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D+G YTC A N D H VN V P T ++ +L SR G ++T
Sbjct: 197 DAGAYTCVAHNPAGEDARLHTVNVL-----VPP---TIKQGADGSGTLVSRP---GELVT 245
Query: 2821 DYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
RG P V WL++G + + R + +TL +S V ++
Sbjct: 246 MVCPVRGSP----------PIHVSWLKDGLPLP---LSQRTLLHGSGHTLRISKVQLADA 292
Query: 2881 GLYTCRAWSAHGNVDMN 2897
G++TC A S G D N
Sbjct: 293 GIFTCVAASPAGVADRN 309
Score = 80.2 bits (189), Expect = 1e-13
Identities = 90/340 (26%), Positives = 130/340 (38%), Gaps = 51/340 (15%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
AV V L C PT+TW + G+ + + + L G L + +A P D+ Y
Sbjct: 856 AVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS-TQVLPGG--QLRIAHASPEDAGNY 912
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
C +N G+ L V +PP + D + L C+ RG P P
Sbjct: 913 LCIAKNSAGSAMGKTRLVVQ-------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPN 965
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
ITW KD + P G F + L + N +D+GTYTC AE
Sbjct: 966 ITWDKDGQ--PVSGAEGKFTIQPSG-ELLVKNLEGQDAGTYTCTAE-------------- 1008
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RV 2843
N V + R+ L P F + D + G + L+ RG PT R+
Sbjct: 1009 ---------NAVGRARRRVHLTILVL--PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRI 1057
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W R VTE V + G TL + V+ +SG Y C W A V A++ V
Sbjct: 1058 GWTVNDRPVTE-----GVSEQDGGSTLQRAAVSREDSGTYVC--W-AENRVGRTQAVSFV 1109
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ V+ G ++ VG I + +G+P P
Sbjct: 1110 HVKE----APVLQGEAFSYLVEPVGGSIQLDCVVRGDPVP 1145
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 16/177 (9%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
P+ L C G+P P ++W+KDG+ + R + L + + D G+Y A
Sbjct: 423 PMELLCDAQGTPQPNITWHKDGQALT----RLENNSRATRVLRVENVQVRDAGLYTCLAE 478
Query: 3244 NNSGAV--SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+ +GA+ S + I P F GL P +L + VEA P+ +TW
Sbjct: 479 SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAP-------GQLVLECSVEAEPAPKITW 531
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+RDG+ L+ A G+ L L A++T D+G Y+CTA N G S + +VE+
Sbjct: 532 HRDGIVLQED--AHTQFPERGRF-LQLQALSTADSGDYSCTARNAAGSTSVAFRVEI 585
Score = 79.8 bits (188), Expect = 2e-13
Identities = 82/311 (26%), Positives = 127/311 (40%), Gaps = 42/311 (13%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + TD T + V LTC PTV+W + G L + + G LE+
Sbjct: 754 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG--ALEI 811
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
A+P + Y+C+ N G A+ V+ + +ASP+ +R +AE E++L
Sbjct: 812 GQALPIHAGRYTCSARNSAGV----AHKHVFLTVQASPVVKPLPSVVR---AVAEEEVLL 864
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C G P P ITW K+ + + Q L G R+A + +PED+G Y C A+NS
Sbjct: 865 PCEASGIPRPTITWQKEGLNVATGVSTQV--LPGGQLRIA--HASPEDAGNYLCIAKNSA 920
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
+ KTR+ Q P N L D G L
Sbjct: 921 GS---------------------AMGKTRLVVQV----PPVIENGLPDLSTTEGSHAFLP 955
Query: 2834 VEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ RG P + W ++G+ V+ F Q L + ++ ++G YTC A +A G
Sbjct: 956 CKARGSPEPNITWDKDGQPVSGAEGK---FTIQPSGELLVKNLEGQDAGTYTCTAENAVG 1012
Query: 2893 NVDMNAAITVV 2903
+T++
Sbjct: 1013 RARRRVHLTIL 1023
Score = 77.0 bits (181), Expect = 1e-12
Identities = 80/291 (27%), Positives = 115/291 (39%), Gaps = 37/291 (12%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+AG LTC V G P P V W+K+ VE A G L + + G Y
Sbjct: 50 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR---LQLSRLQPAQAGTY 106
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+C A NT +A +AV+ R RS+ V R+ V
Sbjct: 107 TCVAENTQAEARKDFVVAVLV----------APRIRSSGVA-----------REHHVLEG 145
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
VRL C+ G PPP V+W KDG + D + +L + D G Y A
Sbjct: 146 QEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVA 205
Query: 3243 RNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL--HEGDELRISAVVEAYPSVGV 3299
N +G H + V P G + L G+ + + V P + V
Sbjct: 206 HNPAGEDARLHT-------VNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHV 258
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
+W +DG+ L S+R + L G L ++ V DAG++TC A++ G A
Sbjct: 259 SWLKDGLPLPLSQRTL--LHGSGH-TLRISKVQLADAGIFTCVAASPAGVA 306
Score = 76.2 bits (179), Expect = 2e-12
Identities = 58/190 (30%), Positives = 77/190 (40%), Gaps = 14/190 (7%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV L D + EGS L C S +P +TW ++G + K + L V
Sbjct: 935 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG--AEGKFTIQPSGELLV 992
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
N D+ Y+CT EN G +L + + P FT D + L L
Sbjct: 993 KNLEGQDAGTYTCTAENAVGRARRRVHLTIL-------VLPVFTTLPGDRSLRLGDRLWL 1045
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C RG P P+I W +D+ + Q DG L + EDSGTY C AEN V
Sbjct: 1046 RCAARGSPTPRIGWTVNDRPVTEGVSEQ-----DGGSTLQRAAVSREDSGTYVCWAENRV 1100
Query: 2774 WTDQITHFVN 2783
Q FV+
Sbjct: 1101 GRTQAVSFVH 1110
Score = 75.8 bits (178), Expect = 3e-12
Identities = 72/294 (24%), Positives = 114/294 (38%), Gaps = 42/294 (14%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCLTIKDI 3114
P +L + G L C +G P P + W K+G + E R T L ++++
Sbjct: 413 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR-------VLRVENV 465
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
+ D G Y+C A + G R+ V + + G P+F + L
Sbjct: 466 QVRDAGLYTCLAESPAGAIEKSFRVRV---------------QAPPNIVGPRGPRFVVGL 510
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
A + L C V P PK++W++DG +V + + E+ L++ + D
Sbjct: 511 ------APGQLVLECSVEAEPAPKITWHRDG--IVLQEDAHTQFPERGRFLQLQALSTAD 562
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y TARN +G+ S V + + P G P + + +
Sbjct: 563 SGDYSCTARNAAGSTS------VAFRVEIHTVPTIRSG-PPAVNVSVNQTALLPCQADGV 615
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ V+W +D V L P L L + V +DAG Y C ASN G
Sbjct: 616 PAPLVSWRKDRVPLDPRSPRFEILPEGS---LRIQPVLAQDAGHYLCLASNSAG 666
Score = 74.5 bits (175), Expect = 6e-12
Identities = 89/306 (29%), Positives = 122/306 (39%), Gaps = 43/306 (14%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LPG + G+ L C+ +G P P + W N V E ++ Q G L ++
Sbjct: 1031 LPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG---VSEQDGG--STLQRAAVS 1085
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+D G Y C A N G R V+ V EA S VE
Sbjct: 1086 REDSGTYVCWAENRVG------RTQAVSFVHVKEAPVLQGEAFSYLVE------------ 1127
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
++L C V G P P + W KDG + R++ Q+ +L I T DD
Sbjct: 1128 ----PVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG---SLTIHRTERDDA 1180
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAY 3294
G Y+ A N G LV+ AP F +EP + GD++ +
Sbjct: 1181 GRYQCLAENEMGVAKKVVILVLQS------APVF--QVEPQDMTVRSGDDVALRCQATGE 1232
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P+ + W + G LR SRR + TL DG L L V T DAG Y C A N +G A+
Sbjct: 1233 PTPTIEWLQAGQPLRASRR-LRTLP-DGS--LWLENVETGDAGTYDCVAHNLLGSATARA 1288
Query: 3355 KVEVIG 3360
+ V G
Sbjct: 1289 FLVVRG 1294
Score = 73.3 bits (172), Expect = 1e-11
Identities = 49/166 (29%), Positives = 79/166 (47%), Gaps = 14/166 (8%)
Query: 2613 LTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENEN 2672
L CSV + P +TW+R+G++L + + L+ L+ +DS +YSCT N
Sbjct: 517 LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST--ADSGDYSCTARNAA 574
Query: 2673 GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDK 2732
G+ S + ++++ PP S+ T +L C+ G P P ++W KD
Sbjct: 575 GSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT-------ALLPCQADGVPAPLVSWRKD-- 625
Query: 2733 QIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
++P D R F L +G L I +D+G Y C A NS +D+
Sbjct: 626 RVPLDPRSPRFEILPEG--SLRIQPVLAQDAGHYLCLASNSAGSDR 669
Score = 72.5 bits (170), Expect = 2e-11
Identities = 50/179 (27%), Positives = 80/179 (44%), Gaps = 14/179 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
T+ + G+ ++L C + P +TW+++G L +L+ + L V N D
Sbjct: 414 TELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL-TRLENNSRATR---VLRVENVQVRD 469
Query: 2661 SAEYSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
+ Y+C E+ GAI S ++V P P P F LA +LVLEC +
Sbjct: 470 AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVG------LAPGQLVLECSVEA 523
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
+P PKITW +D + D Q + L + + DSG Y+C A N+ + +
Sbjct: 524 EPAPKITWHRDGIVLQEDAHTQ---FPERGRFLQLQALSTADSGDYSCTARNAAGSTSV 579
Score = 71.3 bits (167), Expect = 6e-11
Identities = 79/303 (26%), Positives = 129/303 (42%), Gaps = 45/303 (14%)
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAEN 2709
LE+ A SD YSC V N G + L V +PPTF +T +A +
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ-------VPPTFENPKTETVSQVAGS 53
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
LVL C + G P P +TW KD + S + ++ G RL + P +GTYTC A
Sbjct: 54 PLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV--VSRG-GRLQLSRLQPAQAGTYTCVA 110
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
EN+ +++ + V A L + R V ++ V G
Sbjct: 111 ENT---------------QAEARKDFVVA--------VLVAPRIRSSGVAREHHVLEGQE 147
Query: 2830 IGLQVEIRG-CPTRVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
+ L E G P V WL++G + ++ + R +++ G +L L + +++G YTC A
Sbjct: 148 VRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG--SLVLKGLWASDAGAYTCVA 205
Query: 2888 WSAHG-NVDMNAAITVVQPSDLDGK--PAVIVGRPEKDIL----ISVGEDINISFRTQGE 2940
+ G + ++ +V P+ G +V RP + + + I++S+ G
Sbjct: 206 HNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGL 265
Query: 2941 PKP 2943
P P
Sbjct: 266 PLP 268
Score = 70.1 bits (164), Expect = 1e-10
Identities = 88/353 (24%), Positives = 131/353 (37%), Gaps = 59/353 (16%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A L C G P P VVW K+G +++ + + + L D ++ C +
Sbjct: 678 ALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAP-GPQDSAQFECVVS 736
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G+A RL VT PP D V PV L
Sbjct: 737 NEVGEAH---RLYQVTVHV--------------------PPTIADDQTDFTVTMMAPVVL 773
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
TC G P P VSW K G ++ R + Y+ LEI G Y +ARN++G
Sbjct: 774 TCHSTGIPAPTVSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 831
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
H L V V P L + + +E+ + P +TW ++G+
Sbjct: 832 VAHKHVFLTVQAS--PVVKP-----LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLN 884
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
+ + T G +L +A + DAG Y C A N G S GK ++
Sbjct: 885 V---ATGVSTQVLPGG-QLRIAHASPEDAGNYLCIAKNSAG--SAMGKTRLV-------V 931
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++PP VI +P EG + C+ G P+P++ W +D
Sbjct: 932 QVPP-VIENGLP------------DLSTTEGSHAFLPCKARGSPEPNITWDKD 971
Score = 67.7 bits (158), Expect = 7e-10
Identities = 82/310 (26%), Positives = 119/310 (38%), Gaps = 44/310 (14%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PVF+T DR+ G R+ L C+ S P + W N D + DG TL+
Sbjct: 1026 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVN----DRPVTEGVSEQDGGSTLQR 1081
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
DS Y C EN G + + V + P + + L
Sbjct: 1082 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA------PVLQGEAFSYLVEPVGGSIQL 1135
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+C +RG P+P I W KD +P G + L +G L I +D+G Y C AEN
Sbjct: 1136 DCVVRGDPVPDIHWIKDG--LPLRGSHLRHQLQNG--SLTIHRTERDDAGRYQCLAEN-- 1189
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
E V+ VV + QS P F D V G + L+
Sbjct: 1190 --------------EMGVAKKVVI-----LVLQS----APVFQVEPQDMTVRSGDDVALR 1226
Query: 2834 VEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G PT +EWL+ G+ + R R + L+ L +V ++G Y C A + G
Sbjct: 1227 CQATGEPTPTIEWLQAGQPL-RASRRLRTLPDGSLW---LENVETGDAGTYDCVAHNLLG 1282
Query: 2893 NVDMNAAITV 2902
+ A + V
Sbjct: 1283 SATARAFLVV 1292
Score = 65.3 bits (152), Expect = 4e-09
Identities = 79/315 (25%), Positives = 113/315 (35%), Gaps = 51/315 (16%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I++ + D+G YSC+ +N G+A L V T K E ++V G
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENP----KTETVSQVAGS--- 53
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
P+ LTC V G P P V+W KD V + L+++
Sbjct: 54 ---------------PLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV--SRGGRLQLS 96
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPLYKLHEGDELRI 3287
G Y A N D + VAP G+ + + EG E+R+
Sbjct: 97 RLQPAQAGTYTCVAENTQAEAR------KDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 150
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
+ P V W +DG L + DG L L + DAG YTC A N
Sbjct: 151 DCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLWASDAGAYTCVAHNPA 209
Query: 3348 GRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
G + V V+ +PP + + +R G+ V + C V
Sbjct: 210 GEDARLHTVNVL---------VPPTI----------KQGADGSGTLVSRPGELVTMVCPV 250
Query: 3408 VGDPKPDVYWLRDFL 3422
G P V WL+D L
Sbjct: 251 RGSPPIHVSWLKDGL 265
Score = 63.7 bits (148), Expect = 1e-08
Identities = 83/361 (22%), Positives = 144/361 (39%), Gaps = 61/361 (16%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEG 3120
+L G+ L C G+P P V W+K+G + ++ G + +G L +K + D G
Sbjct: 142 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS--LVLKGLWASDAG 199
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
Y+C A N G+ + + V+ T+ ++ A+ G T+ R +
Sbjct: 200 AYTCVAHNPAGEDARLHTVNVLVPPTI---------KQGADGSG------TLVSRPGEL- 243
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
V + C V GSPP VSW KDG + +R + HTL I+ L D G++
Sbjct: 244 ----VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG--HTLRISKVQLADAGIFTC 297
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A + +G + L + + + + P + A A+P +
Sbjct: 298 VAASPAGVADRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSR--------ARPGAFPCLSC 349
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+DG +++ + L L AV D+G Y+C A +E G A ++ V+
Sbjct: 350 RGMKDG-------EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM 402
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
EP P + S +P + G + + C+ G P+P++ W +
Sbjct: 403 ------EP--------PHIEDSGQPTEL------SLTPGAPMELLCDAQGTPQPNITWHK 442
Query: 3420 D 3420
D
Sbjct: 443 D 443
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 10/160 (6%)
Query: 2613 LTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENEN 2672
L C S P V W+++G LD +L+ + L + P DSA++ C V NE
Sbjct: 680 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 739
Query: 2673 GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDK 2732
G + V+ +PPT D +VL C G P P ++W K
Sbjct: 740 GEAHRLYQVTVH-------VPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGA 792
Query: 2733 QIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
Q+ + G + Y L I P +G YTC A NS
Sbjct: 793 QLGARG---SGYRVSPSGALEIGQALPIHAGRYTCSARNS 829
Score = 61.3 bits (142), Expect = 6e-08
Identities = 62/206 (30%), Positives = 87/206 (42%), Gaps = 38/206 (18%)
Query: 3045 LAGDR-PEFV-DILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
+ G R P FV + PGQL L CSV+ +P P + W ++G ++E+A +QF
Sbjct: 498 IVGPRGPRFVVGLAPGQLV--------LECSVEAEPAPKITWHRDGIVLQEDA---HTQF 546
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEV 3162
L ++ ++ D G YSC A N G S R+ + T T+ RS
Sbjct: 547 PERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTI----------RSG-- 594
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF 3222
PP V L CQ G P P VSW KD V D R +++
Sbjct: 595 ----PPAV-------NVSVNQTALLPCQADGVPAPLVSWRKD--RVPLDPRSPRFEILPE 641
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGA 3248
+L I P D G Y A N++G+
Sbjct: 642 GSLRIQPVLAQDAGHYLCLASNSAGS 667
Score = 51.6 bits (118), Expect = 5e-05
Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 34/203 (16%)
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
EQ +L++ D G Y A + +G H L V + ++ G L
Sbjct: 364 EQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP--PHIEDS---GQPTELSL 418
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA--VTTRDAG 3337
G + + + P +TW++DG +A+ L+ + + L V RDAG
Sbjct: 419 TPGAPMELLCDAQGTPQPNITWHKDG-------QALTRLENNSRATRVLRVENVQVRDAG 471
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
+YTC A + G S +V V + PP ++ P R PR
Sbjct: 472 LYTCLAESPAGAIEKSFRVRV---------QAPPNIVGP-----------RGPRFVVGLA 511
Query: 3398 GDTVIIECEVVGDPKPDVYWLRD 3420
+++EC V +P P + W RD
Sbjct: 512 PGQLVLECSVEAEPAPKITWHRD 534
Score = 49.6 bits (113), Expect = 2e-04
Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 36/250 (14%)
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
RD RV A P C+ GSP P V W+KDG+++ + ++ Y+ + L + D
Sbjct: 672 RDLRVLALLP----CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQD 727
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
+E N G H V + +A + + + + + ++
Sbjct: 728 SAQFECVVSNEVG--EAHRLYQVTVHVPPTIADD-----QTDFTVTMMAPVVLTCHSTGI 780
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P+ V+W + G +L +R + + G +E+ A AG YTC+A N G A
Sbjct: 781 PAPTVSWSKAGAQL-GARGSGYRVSPSGALEIGQALPI--HAGRYTCSARNSAGVAHK-- 835
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
V T Q S P + P+ P +R E V++ CE G P+P
Sbjct: 836 --HVFLTVQAS-PVVKPL-----------PSVVRAVAEEE------VLLPCEASGIPRPT 875
Query: 3415 VYWLRDFLKV 3424
+ W ++ L V
Sbjct: 876 ITWQKEGLNV 885
Score = 41.5 bits (93), Expect = 0.052
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 8/101 (7%)
Query: 2820 TDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTET 2878
T+ + G + L + +G P + W ++G+++T + N+R L + +V
Sbjct: 414 TELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRA-----TRVLRVENVQVR 468
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK--PAVIVG 2917
++GLYTC A S G ++ + + V P ++ G P +VG
Sbjct: 469 DAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVG 509
Score = 37.5 bits (83), Expect = 0.84
Identities = 38/161 (23%), Positives = 62/161 (38%), Gaps = 29/161 (18%)
Query: 2613 LTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENEN 2672
L C P V+W ++ V LD + + L +G +L + + D+ Y C N
Sbjct: 608 LPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG--SLRIQPVLAQDAGHYLCLASNSA 665
Query: 2673 GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDK 2732
G+ +L+V LA +L C G P P + W+KD +
Sbjct: 666 GSDRQGRDLRV----------------------LA----LLPCEASGSPKPLVVWWKDGQ 699
Query: 2733 QIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
++ + A+ L L + P P+DS + C N V
Sbjct: 700 KLDFRLQQGAYRLLPSNA-LLLTAPGPQDSAQFECVVSNEV 739
Score = 34.3 bits (75), Expect = 7.9
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID 3117
G L GE + C V+G P V W+K+G + + +G L I + +
Sbjct: 234 GTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLS---QRTLLHGSGHTLRISKVQLA 290
Query: 3118 DEGRYSCEATNTHGKA 3133
D G ++C A + G A
Sbjct: 291 DAGIFTCVAASPAGVA 306
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 92.7 bits (220), Expect = 2e-17
Identities = 88/341 (25%), Positives = 131/341 (38%), Gaps = 27/341 (7%)
Query: 3039 SSIGVGLAGDRPEFVDILP--GQLKILAGETAN---LTCSVKG-KPVPGVVWMKNGHEVE 3092
S GV +A + ++I P GQ+ GE C ++ V W ++E
Sbjct: 25054 SQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLE 25113
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--- 3149
+ +G L +KDI D+G Y C+ N +G+ S+YA L V R V++
Sbjct: 25114 NSEKYEITYEDGV-AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYC 25172
Query: 3150 --ADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEE 3207
K+KR + PP+FT+ L ++ VR + P P V+WYK G++
Sbjct: 25173 RRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK 25232
Query: 3208 VVYDKRRNKY---QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
+ KY D+ + L I DD Y V ARN G SC L V
Sbjct: 25233 IKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TL 25287
Query: 3265 VAPEFCCGLEPLYK-------LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMT 3317
P L P++K EG + V P + W +DG L +
Sbjct: 25288 HPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 25347
Query: 3318 LDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ L + D G Y TA+N G S ++V
Sbjct: 25348 HEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 85.4 bits (202), Expect = 3e-15
Identities = 60/196 (30%), Positives = 86/196 (43%), Gaps = 10/196 (5%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
TL N+ P L T G + + P ++WY+ LL K K L
Sbjct: 3184 TLYVNAPEPPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKC-KFL 3242
Query: 2645 VDGL-ITLEVLNAVPSDSAEYSCTVENENGAISTSANLK------VYPSFEASPIPPTFT 2697
DG TL ++ A P D+A Y+C +N+ G +TSA+L V P E PP
Sbjct: 3243 HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAII 3302
Query: 2698 RSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNP 2757
++DT +CR+ G L K++W+ DK+I R+ + +L I
Sbjct: 3303 TPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEA 3360
Query: 2758 TPEDSGTYTCKAENSV 2773
PED GTYT A N+V
Sbjct: 3361 YPEDEGTYTFVANNAV 3376
Score = 84.6 bits (200), Expect = 6e-15
Identities = 107/443 (24%), Positives = 174/443 (39%), Gaps = 42/443 (9%)
Query: 2941 PK-PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
PK P PE P V+D + VSL+W + + V Y +E + R +
Sbjct: 23825 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKVVRHNK 23884
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
IT + L EY FR+ +N G E+S S + D+P PG+
Sbjct: 23885 TQITT-TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPS----QPGE 23939
Query: 3060 LKILAGETANLTCSVK------GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
L+IL+ ++T + GK + G W++ + + A + +++ D TI
Sbjct: 23940 LEILSISKDSVTLQWEKPECDGGKEILGY-WVEY-RQSGDSAWKKSNKERIKDKQFTIGG 23997
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
+ E + A N G + RT KL S E G
Sbjct: 23998 LLEATEYEFRVFAENETGLSRPR--------RTAMSIKTKLT---SGEAPG-----IRKE 24041
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
++D + +L+CQ++G P P + WY+ G+E++ ++ D + HTL + +
Sbjct: 24042 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 24101
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG--LEPLYKLHEGDELRISAVV 3291
D GVY A N G V L++ P+F G L+ Y G LR+ +
Sbjct: 24102 DEGVYTCIATNEVGEVETSSKLLLQ------ATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24155
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASNEVGRA 3350
P +TW+ G +L + I + + L + V + AG Y SN G
Sbjct: 24156 IGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV 24214
Query: 3351 STSGKVEVIGTDQTSEPRIPPVV 3373
VE+ D+ +P P V+
Sbjct: 24215 DAILDVEI--QDKPDKPTGPIVI 24235
Score = 83.0 bits (196), Expect = 2e-14
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F +++ G L+ +VI P + W+ NGVLL Y+ +L +
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEA------------------SPIPPT 2695
L D EY+C N+ G SA LK+ E P PP
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
F + ++ + E + G+P P +TWFK++KQ+ + Y + +G ++
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636
Query: 2756 NPTPEDSGTYTCKAEN 2771
+P EDSG Y CKAEN
Sbjct: 3637 DPQREDSGLYICKAEN 3652
Score = 80.6 bits (190), Expect = 9e-14
Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 9/185 (4%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG+ ++D N VSL+W K + + +L Y VE + +G +W +
Sbjct: 15555 PGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVE---MQTKGSDKWATCATVKVTEATI 15611
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDILPGQLKILAGETA 3068
L QGEEY FRV+ +N G + Q S + +A D P +L +LAGE
Sbjct: 15612 TGLIQGEEYSFRVSAQNEKGISDPRQLSVPV---IAKDLVIPPAFKLLFNTFTVLAGEDL 15668
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
+ G+P P V W K+ +++ R+ ++ + LTIKD +D G Y + TN
Sbjct: 15669 KVDVPFIGRPTPAVTWHKDNVPLKQTT-RVNAESTENNSLLTIKDACREDVGHYVVKLTN 15727
Query: 3129 THGKA 3133
+ G+A
Sbjct: 15728 SAGEA 15732
Score = 80.2 bits (189), Expect = 1e-13
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 10/196 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P +D ++L W + ++ Y +E +G RWV T ++ +
Sbjct: 21361 PGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEK----RQGNERWVRCNFTDVSECQY 21416
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ---LKILAG 3065
L G+ Y FR+ RN G SS I + + P V+ P L I +G
Sbjct: 21417 TVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSG 21476
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
E+ + V+G+PVP V W K+G E+E+ + G L ++D D G Y+ E
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLG-STSLFVRDATRDHRGVYTVE 21535
Query: 3126 ATNTHGKASTYARLAV 3141
A N G A ++ V
Sbjct: 21536 AKNASGSAKAEIKVKV 21551
Score = 79.8 bits (188), Expect = 2e-13
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 5/198 (2%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL---DN 2636
I + R R P F+ L ++TA G V+ ++ +P VTWY++G + DN
Sbjct: 25179 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 25238
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPP 2694
KY + GL L + + D AEY+ N+ G S A L V +P S + P
Sbjct: 25239 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 25298
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
F R + + + E R+ G P P + W KD + + + + L I
Sbjct: 25299 MFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHI 25358
Query: 2755 DNPTPEDSGTYTCKAENS 2772
+ PED+G Y A N+
Sbjct: 25359 RDTLPEDTGYYRVTATNT 25376
Score = 79.4 bits (187), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 79.4 bits (187), Expect = 2e-13
Identities = 87/358 (24%), Positives = 137/358 (38%), Gaps = 35/358 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITL 2651
KPVF +EG+ + V+ P W+ +G + N ++ + DG +L
Sbjct: 1410 KPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ A PSDS E++ +N G S S L V + P F +++ + L
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTV--EAVEHQVKPMFVEKLKNVNIKEGSRL 1527
Query: 2712 VLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
++ R G P P I W K+ D +P G L ID+ +DS YT A
Sbjct: 1528 EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1587
Query: 2771 NSVWTDQITHFVNFTGRESQVSPN---VV---TAEKTRIARQSLE--------------- 2809
N D VN ++ P ++ T IA LE
Sbjct: 1588 NKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGD 1647
Query: 2810 ------SRRPHFGNVLTDYQVARGGTIGLQVEIR--GCPTR-VEWLREGRSVTEVYRNAR 2860
++P F LT ++ R G + + PT VEWL +G+ + E R
Sbjct: 1648 LYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPL-EAANRLR 1706
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G +L +SG+ TCRA + +G +A + V L + + GR
Sbjct: 1707 MINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGR 1764
Score = 78.6 bits (185), Expect = 4e-13
Identities = 60/190 (31%), Positives = 87/190 (45%), Gaps = 10/190 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N V+L W K + + Y VE + +G RW++ T + F
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDL-PDG--RWMKASFTNVLETEF 18165
Query: 3009 DAFNLKQGEEYHFRVTPRNRYG-WGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL---A 3064
L + + Y FRV RN G + E S +S +I D P + P ++ A
Sbjct: 18166 TVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN-ASLDPKYKDVIVVHA 18224
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L ++GKP+P VVW K+G E+EE A RM + L +KD D G+Y
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYIL 18284
Query: 3125 EATNTHGKAS 3134
+ +N G S
Sbjct: 18285 KLSNVGGTKS 18294
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 4/208 (1%)
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD- 3211
+L+ +++E Y P F ++ + R +V+G P P+ W+ DG+++V D
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDY 1455
Query: 3212 KRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC 3271
+ +++ +L I P D G + V A+N +G S L V+ + V P F
Sbjct: 1456 THKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE-AVEHQVKPMFVE 1514
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD-RDGQIELALAA 3330
L+ + + EG L + P+ + W ++ + P + + ++ G+ L + +
Sbjct: 1515 KLKNV-NIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1573
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEV 3358
++D+ YT TA N+ GR +T KV V
Sbjct: 1574 TVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Score = 77.4 bits (182), Expect = 9e-13
Identities = 61/217 (28%), Positives = 97/217 (44%), Gaps = 14/217 (6%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDE 3220
V PPQ L+ VQ+ P R + G P PK+SWYK+ E+++ + K+ D
Sbjct: 3187 VNAPEPPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKE-EQLLSTGFKCKFLHDG 3245
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP---LY 3277
Q +TL + +D VY A+N+ G + L V+ + V+P+ + P +
Sbjct: 3246 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE--VPEVVSPDQEMPVYPPAIIT 3303
Query: 3278 KLH-----EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L EG R V + V+WY +++PSR MT D +L +A
Sbjct: 3304 PLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAY 3361
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
D G YT A+N VG+ S++ + + + RI
Sbjct: 3362 PEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERI 3398
Score = 77.4 bits (182), Expect = 9e-13
Identities = 60/211 (28%), Positives = 94/211 (44%), Gaps = 8/211 (3%)
Query: 2935 FRTQGEPKPKAVPERIPGEPC--VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAE 2992
F +PK P PG P V D + + L W ++ Y V+ L+G
Sbjct: 8490 FSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8549
Query: 2993 GGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF 3052
+R E I + + +++G +Y RV+ N G G +T + V + P
Sbjct: 8550 KWSRCTEKMIK-VRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQP-VTVAEPQEPPAV 8607
Query: 3053 -VDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
+D+ + G ++I+AG+T + V G+PVP VW K E++++ R+ G L
Sbjct: 8608 ELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD--RVVIDNVGTKSELI 8665
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
IKD D GRY ATN+ G AR+ V
Sbjct: 8666 IKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Score = 77.0 bits (181), Expect = 1e-12
Identities = 57/204 (27%), Positives = 89/204 (43%), Gaps = 11/204 (5%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGI 3002
P A P + P P V D VSLAW + + + V Y +E + W +
Sbjct: 23532 PIAPPGK-PQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQH---EWTKCNT 23587
Query: 3003 TP--LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFV--DILPG 3058
TP + + +L QG EY FRV N G GE ++ ++ V + P++ +
Sbjct: 23588 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 23647
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + G LT +KGKP P W K G ++ + A TS+ + L IK+ + D
Sbjct: 23648 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH---TELVIKEADRGD 23704
Query: 3119 EGRYSCEATNTHGKASTYARLAVV 3142
G Y N GK + Y ++ V+
Sbjct: 23705 SGTYDLVLENKCGKKAVYIKVRVI 23728
Score = 77.0 bits (181), Expect = 1e-12
Identities = 97/429 (22%), Positives = 181/429 (42%), Gaps = 39/429 (9%)
Query: 2951 PGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW--VELGITPLNS 3007
P P V++ N ++W + + Y VE A+ GA W V I+ + +
Sbjct: 24229 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK--CEAKEGAEWQLVSSAIS-VTT 24285
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
NL + Y+FRV+ +N +G + + SS + + ++P PG+ I A
Sbjct: 24286 CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG----APGKPTITAVTK 24341
Query: 3068 ANLTCSVKGKPVPGVVWMKNGH--EVEEEAGRMTSQFNGF--DCCLTIKDI--NIDDEGR 3121
+ + K G ++N + + E++ + S + ++K++ ++ E R
Sbjct: 24342 DSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 24401
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
CE N G++ + +++ ++D ++ P F LR+ V+
Sbjct: 24402 VKCE--NLGGESEW----SEISEPITPKSDVPIQA-----------PHFKEELRNLNVRY 24444
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYE 3239
L C+V G P P V WY+ G+E++ D + + Q+ + +H L IA DD VY+
Sbjct: 24445 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 24504
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
V A N G+VS L V+ + ++ P+ G+ ++ L G+ + I P +
Sbjct: 24505 VRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHAL-RGEVVSIKIPFSGKPDPVI 24562
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + + + + + R + V +DAG Y A N G + +++V
Sbjct: 24563 TWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV- 24621
Query: 3360 GTDQTSEPR 3368
D PR
Sbjct: 24622 -ADVPDPPR 24629
Score = 76.6 bits (180), Expect = 1e-12
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 76.6 bits (180), Expect = 1e-12
Identities = 61/219 (27%), Positives = 99/219 (45%), Gaps = 15/219 (6%)
Query: 2946 VPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP- 3004
+P PG+P V+D + VSL W + + ++ Y VE+ + G +WV P
Sbjct: 12691 MPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP---GDKWVRCNTAPH 12747
Query: 3005 ---LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI---LPG 3058
+ A L++ +Y FR R S+ S + + LA + P +D+ +
Sbjct: 12748 QIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTI-LAENVPPRIDLSVAMKS 12806
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINID 3117
L + AG L +V GKP+P V W K+G ++ G +M Q N C L + +N
Sbjct: 12807 LLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN--LCTLELFSVNRK 12864
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
D G Y+ A N+ G S +L V+ D+ A K+ +
Sbjct: 12865 DSGDYTITAENSSGSKSATIKLKVL-DKPGPPASVKINK 12902
Score = 74.1 bits (174), Expect = 8e-12
Identities = 58/231 (25%), Positives = 97/231 (41%), Gaps = 24/231 (10%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PPT +++ + + LEC I G P P +TW+++D QI S +Q + G+ RL
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 954
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFV------NFTGRESQVSPNVVTAEKTRIARQ 2806
I EDSG +TC A N T + ++ F + V+ T EK + +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 2807 SL---------------ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
+ E P+F ++ GG++ ++ G P V W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 2851 SVTEVYRNARVFVEQ-GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+T YR + +Q G L +S ++G YT + HG +A++
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 73.7 bits (173), Expect = 1e-11
Identities = 92/369 (24%), Positives = 140/369 (37%), Gaps = 18/369 (4%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++S T G G P F+ P K++ G + C V G P P V W K+G +
Sbjct: 1020 DTSLTEEQAGPGEPA-APYFIT-KPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1077
Query: 3093 EEAGRMTSQFNGF--DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
R +N +C L I DD G Y+ N HG+ S A L + EA
Sbjct: 1078 T-GYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-------LEEA 1129
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +L + E+ Y Q T +++ V T P + + + + +
Sbjct: 1130 DYELLMKSQQEML--YQTQVTAFVQEPEVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEV-TARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R +D++FH + + + T + VD V F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
++ Y++ EG + + YP + WY+DG R++ R M +DG+ L +
Sbjct: 1248 DLRIKN-YRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI-R 3388
V D G+YT ASN G A SGK+ V P P + S P + R
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 3389 KP-RSSEAR 3396
P R S AR
Sbjct: 1367 SPIRMSPAR 1375
Score = 73.7 bits (173), Expect = 1e-11
Identities = 54/200 (27%), Positives = 85/200 (42%), Gaps = 6/200 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I G+ A L+ +V G P P + W NG + A F+G D L I ++DEG
Sbjct: 3468 ISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD-YKFVFDGDDHSLIILFTKLEDEGE 3526
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE---GDYPPQFTMRLRDRR 3178
Y+C A+N +GK A L + + D + + + +E G PP F L+ R
Sbjct: 3527 YTCMASNDYGKTICSAYLKI-NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR 3585
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTLEIAPTNLDDGGV 3237
P V+G P P V+W+K+ +++ + T + +D G+
Sbjct: 3586 CAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGL 3645
Query: 3238 YEVTARNNSGAVSCHCGLVV 3257
Y A N G +C L+V
Sbjct: 3646 YICKAENMLGESTCAAELLV 3665
Score = 73.3 bits (172), Expect = 1e-11
Identities = 56/184 (30%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 3201 WYKDGEEVVYD-KRRNKYQDEQ-FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
WYKDG E+ + + R+KY E+ H + I+ T D G Y A N +V+ +
Sbjct: 3133 WYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLY------ 3186
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ A P+ L+P+ + G R A++ P ++WY++ L +
Sbjct: 3187 --VNAPEPPQVLQELQPV-TVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFL- 3242
Query: 3319 DRDGQ-IELALAAVTTRDAGVYTCTASNEVGRASTSGKV-----EVIGTDQTSEPRIPPV 3372
DGQ L L DA VYTC A N+ G A+TS + EV+ DQ P PP
Sbjct: 3243 -HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPA 3300
Query: 3373 VISP 3376
+I+P
Sbjct: 3301 IITP 3304
Score = 73.3 bits (172), Expect = 1e-11
Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRK----PVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+S A S +S++ E+ T + ++ + F T + EG R+ L ++ ++D
Sbjct: 26513 KSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATD-- 26570
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
V W NGV L N +YR + TL + A D +C + + G + +L +
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL- 26629
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
S E S P ++ + +N ++ C I G+P P+I WFK++ I S +
Sbjct: 26630 -SKELSDAPAFISQPRSQNINEGQN-VLFTCEISGEPSPEIEWFKNNLPI-SISSNVSIS 26686
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ V L I N + DSG YT KA+N
Sbjct: 26687 RSRNVYSLEIRNASVSDSGKYTIKAKN 26713
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPNPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 71.7 bits (168), Expect = 4e-11
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 7/187 (3%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS-FD 3009
P P VVD + +SLAW K ++ Y +E + R V T N+ F
Sbjct: 22848 PSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR-VHTNATIRNTEFT 22906
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP--EFVDILPGQLKILAGET 3067
+LK G++Y FRV N G E S++ + I + P E D L + I AG +
Sbjct: 22907 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 22966
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L SV G+P P + W K G ++ A T++ L + +N D G+Y+ EA
Sbjct: 22967 LRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGKYTIEAE 23023
Query: 3128 NTHGKAS 3134
N GK S
Sbjct: 23024 NQSGKKS 23030
Score = 71.3 bits (167), Expect = 6e-11
Identities = 88/314 (28%), Positives = 138/314 (43%), Gaps = 31/314 (9%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAW--PKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
K K P PG+P V D N +++W PKSD +P+ Y +E E +WV
Sbjct: 11201 KHKFSPPSPPGKPVVTDITENAATVSWTLPKSD--GGSPITGYYMER----REVTGKWVR 11254
Query: 3000 LGITPLN--SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP 3057
+ TP+ F L +G Y FRV N G + S +S I +P I P
Sbjct: 11255 VNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPI-KACRPIKPPGPPINP 11313
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDINI 3116
+LK + ETA+L V KP+ G+ VE ++ G T+Q+N IN
Sbjct: 11314 -KLKDKSRETADL---VWTKPLSDGGSPILGYVVECQKPG--TAQWN---------RINK 11358
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+ R + + Y R + V E + + E + +PP+ + +
Sbjct: 11359 DELIRQCAFRVPGLIEGNEY-RFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTC 11417
Query: 3177 R---RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
R V+ +R+ +V G P P ++W K+G+ +V +KR + QD L+I
Sbjct: 11418 RDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA 11477
Query: 3234 DGGVYEVTARNNSG 3247
D G Y ++A+N+SG
Sbjct: 11478 DHGKYIISAKNSSG 11491
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 11/198 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N V+L W K + + Y VE + EG RW++ T + F
Sbjct: 15945 PGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKEL-PEG--RWMKASFTNIIDTHF 16001
Query: 3009 DAFNLKQGEEYHFRVTPRNRYG-WGESSQTSSSIGVGLAGDRPEFVDILP---GQLKILA 3064
+ L + Y FRV RN G + E S+++ +I D P + + P + + A
Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR-ISMDPKYKDTIVVHA 16060
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE+ + + GKP+P + W+K E+ A R+ + F L++KD D G Y
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTA-RLEIKSTDFATSLSVKDAVRVDSGNYIL 16119
Query: 3125 EATNTHGKASTYARLAVV 3142
+A N G+ S + V+
Sbjct: 16120 KAKNVAGERSVTVNVKVL 16137
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/202 (27%), Positives = 84/202 (41%), Gaps = 7/202 (3%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL- 3005
P PG P V D + VSL W + V+ Y +E + G RW++ T +
Sbjct: 22441 PVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 22500
Query: 3006 -NSFDAFNLKQGEEYHFRVTPRNRYG---WGESSQTSSSIGVGLAGDRPEFVDILPGQL- 3060
N F L +G+ Y FRV +N G G S + A + E L G L
Sbjct: 22501 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 22560
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
I AG L +V GKP P ++W K E+ + +++ Q+ G IK + D G
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSLQYTGKRATAVIKFCDRSDSG 22619
Query: 3121 RYSCEATNTHGKASTYARLAVV 3142
+Y+ N G + + V+
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVL 22641
Score = 71.3 bits (167), Expect = 6e-11
Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 17/198 (8%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
GE ++ P P V W K+G +++ + + T + + LTI + DD+ Y
Sbjct: 25207 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEY 25266
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+ A N +G+ S A+L V D+ L+ P F L + Q
Sbjct: 25267 TVVARNKYGEDSCKAKLTVTLHPP--PTDSTLR------------PMFKRLLANAECQEG 25312
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK-YQDEQFHTLEIAPTNLDDGGVYEVT 3241
V +V G PPP + W KDG+ + ++ ++ L I T +D G Y VT
Sbjct: 25313 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25372
Query: 3242 ARNNSGAVSCHCGLVVDK 3259
A N +G+ SC L V++
Sbjct: 25373 ATNTAGSTSCQAHLQVER 25390
Score = 70.5 bits (165), Expect = 1e-10
Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 12/197 (6%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ +G+ A + G+P P + W K ++ + +G + L + + +D
Sbjct: 3204 VQSGKPARFCAMISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3262
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+CEA N +G A+T A L+V E + ++ V YPP L+D
Sbjct: 3263 YTCEAKNDYGVATTSASLSV-------EVPEVVSPDQEMPV---YPPAIITPLQDTVTSE 3312
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P R C+V G+ KVSWY +++ + Q E + LEIA +D G Y
Sbjct: 3313 GQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3371
Query: 3242 ARNNSGAVSCHCGLVVD 3258
A N G VS L ++
Sbjct: 3372 ANNAVGQVSSTANLSLE 3388
Score = 70.5 bits (165), Expect = 1e-10
Identities = 56/196 (28%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 2951 PGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS 3007
PGEP + D G +V L W + D +P L+Y VE L G++ R V G
Sbjct: 11604 PGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER-VHKGSIKETH 11662
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
+ + + Y FRV +N G + +T + V +P L G L + AG+T
Sbjct: 11663 YMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVV-VKEDLQKPVLDLKLSGVLTVKAGDT 11721
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
L V+GKP P V W K+ + + R+ ++ D G+Y A
Sbjct: 11722 IRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTA 11781
Query: 3127 TNTHGKASTYARLAVV 3142
TNT G YA + V+
Sbjct: 11782 TNTAGSFVAYATVNVL 11797
Score = 70.1 bits (164), Expect = 1e-10
Identities = 63/209 (30%), Positives = 85/209 (40%), Gaps = 12/209 (5%)
Query: 2941 PKP-KAV-PERIPGEPCV---VDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGA 2995
PKP KA+ P PG P VD VSL W K D +P+ Y VE EG
Sbjct: 10901 PKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE---YQEEGTQ 10957
Query: 2996 RWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS-SIGVGLAGDRPEF-V 3053
W++ L+QG+ Y FRV N G G T L E V
Sbjct: 10958 DWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDV 11017
Query: 3054 DILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
++ G L + AG T ++G PVP W +G E++ + T + + F LTIK+
Sbjct: 11018 KLIEG-LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKN 11075
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y +N G + L V+
Sbjct: 11076 CLRRDTGEYQITVSNAAGSKTVAVHLTVL 11104
Score = 70.1 bits (164), Expect = 1e-10
Identities = 80/324 (24%), Positives = 135/324 (41%), Gaps = 47/324 (14%)
Query: 2607 EGSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
EG VK C + + T VTWY L+N KY DG+ L V + D Y
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143
Query: 2666 CTVENENGAISTSANL------KVYPSFEASPI---------------PPTFTRSI-RDT 2703
C V N+ G S+ A L +VY + + PP FT + T
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 25203
Query: 2704 FHLAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLAD-GVCRLAIDNPTPED 2761
++ EN + I P P +TW+K ++I P D + + +D G+ +L I++ T +D
Sbjct: 25204 AYVGEN-VRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25262
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
YT A N G +S + VT + + RP F +L +
Sbjct: 25263 DAEYTVVARNKY------------GEDSCKAKLTVTLHPP----PTDSTLRPMFKRLLAN 25306
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTET 2878
+ G ++ ++ + G P ++W ++G+ ++ + N + + +GL Y L + D
Sbjct: 25307 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS-LGPNIEI-IHEGLDYYALHIRDTLPE 25364
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITV 2902
++G Y A + G+ A + V
Sbjct: 25365 DTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 70.1 bits (164), Expect = 1e-10
Identities = 57/238 (23%), Positives = 107/238 (44%), Gaps = 23/238 (9%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPL--PKITWFKDDKQIPSDGRYQAFYLADGV 2749
PP T+ ++ A E+ L C + L ++TW+KD K++ +G +Q Y ADG
Sbjct: 26220 PPKITQFLKAE---ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGT 26276
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQIT------HFVNFTGRESQVSPNVVTAEKT-- 2801
L I+N T D G Y C+ T + F + + S++S + +KT
Sbjct: 26277 YELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTE 26336
Query: 2802 -RIARQSLE------SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE-WLREGRSVT 2853
+ R++ S +P L D V+ V+ G P W ++G+++T
Sbjct: 26337 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26396
Query: 2854 EVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+ + ++ ++G + L + ++SGLYTC ++ G+V + +T+ D + +
Sbjct: 26397 QGGK-YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453
Score = 69.7 bits (163), Expect = 2e-10
Identities = 50/200 (25%), Positives = 89/200 (44%), Gaps = 10/200 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P + V D G +++AW + +P++ Y VE +G E +W+ + P+
Sbjct: 7787 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTE---KWMRVNSRPIK 7843
Query: 3007 SFDAFNLKQG----EEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI 3062
F +++G +EY RV N G E S+ S ++ V D +D+ + +
Sbjct: 7844 DL-KFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV-VAKDPDCKPTIDLETHDIIV 7901
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+ GE ++ + PVP V W K+G EV + + R+T + + L + D G Y
Sbjct: 7902 IEGEKLSIPVPFRAVPVPTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIY 7960
Query: 3123 SCEATNTHGKASTYARLAVV 3142
+ N G A+ + V+
Sbjct: 7961 TITLENKLGSATASINVKVI 7980
Score = 69.7 bits (163), Expect = 2e-10
Identities = 61/210 (29%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP P P PG+P V + VSL W K A + Y VE + +G RW++
Sbjct: 19180 EPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERREL-PDG--RWLK 19236
Query: 3000 LGITPLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE----FV 3053
T + F+ L + + Y FRV RN S+ S S G + D E +
Sbjct: 19237 CNYTNIQETYFEVTELTEDQRYEFRVFARNAAD--SVSEPSESTGPIIVKDDVEPPRVMM 19294
Query: 3054 DI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
D+ + + AGE + + G+P+P + W K+G E+EE A R LT+K
Sbjct: 19295 DVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA-RTEIISTDNHTLLTVK 19353
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVV 3142
D D G+Y N G S V+
Sbjct: 19354 DCIRRDTGQYVLTLKNVAGTRSVAVNCKVL 19383
Score = 68.9 bits (161), Expect = 3e-10
Identities = 60/221 (27%), Positives = 87/221 (39%), Gaps = 28/221 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ GE+ L C + G P P V W + +++E + +G L I++ +D GR
Sbjct: 908 VIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI-ARLMIREAFAEDSGR 966
Query: 3122 YSCEATNTHGKASTYARLAV------------------------VTDRTVWEADAKLKRE 3157
++C A N G ST LAV V R V D L E
Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
++ E P T + + V+ V CQV G+P P V W K G + R
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGG-SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVS 1085
Query: 3218 QDEQFH--TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++Q L I+ T DD G Y + RN G S L+
Sbjct: 1086 YNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1126
Score = 68.9 bits (161), Expect = 3e-10
Identities = 54/191 (28%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 2945 AVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP 3004
A P PG+ + D SL W K + + VL Y VE G E +W + +
Sbjct: 17713 AEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE---KWSIVAESK 17769
Query: 3005 LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKIL 3063
+ + L G+EY FRV N G + + +P LP I
Sbjct: 17770 VCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLK--LPFNTYSIQ 17827
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AGE + V G+P P + W+K+G +++ R+ + L IK+ N DD G+Y+
Sbjct: 17828 AGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT-RVNVEETATSTVLHIKEGNKDDFGKYT 17886
Query: 3124 CEATNTHGKAS 3134
ATN+ G A+
Sbjct: 17887 VTATNSAGTAT 17897
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/195 (26%), Positives = 90/195 (46%), Gaps = 4/195 (2%)
Query: 2950 IPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFD 3009
+P + VVD + V+LAW K + + Y +E+ G E + V L T L
Sbjct: 23140 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-T 23198
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LKILAGET 3067
+L +GE+Y FR+ +N G E +T +++ V P + +P + + + AG
Sbjct: 23199 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23258
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L + G+P P W G ++ E+ R+T + + LTI++ I D G Y+ E
Sbjct: 23259 VELVIPIAGRPPPAASWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELK 23317
Query: 3128 NTHGKASTYARLAVV 3142
N G S ++ ++
Sbjct: 23318 NVTGTTSETIKVIIL 23332
Score = 68.1 bits (159), Expect = 5e-10
Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 13/191 (6%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N ++L W K + + Y VE + +G RW++ T + F
Sbjct: 17027 PGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDL-PDG--RWMKASFTNVIETQF 17083
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI-----LPGQLKIL 3063
L + + Y FRV +N G S+ S S G A D E I + +
Sbjct: 17084 TVSGLTEDQRYEFRVIAKNAAG--AISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17141
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AGET L V GKP+P + W++ E+EE A R + F L +KD D G+Y
Sbjct: 17142 AGETFRLEADVHGKPLPTIEWLRGDKEIEESA-RCEIKNTDFKALLIVKDAIRIDGGQYI 17200
Query: 3124 CEATNTHGKAS 3134
A+N G S
Sbjct: 17201 LRASNVAGSKS 17211
Score = 68.1 bits (159), Expect = 5e-10
Identities = 59/210 (28%), Positives = 86/210 (40%), Gaps = 11/210 (5%)
Query: 2941 PKPKAVPERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW 2997
P+P E+ P P VVD + LAW K D + + Y +E + +G W
Sbjct: 22040 PEPIVATEQ-PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE---MRQKGSDLW 22095
Query: 2998 VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP--EFVDI 3055
VE G T +F L + EY FRV +N G+ E + SS+ + P + I
Sbjct: 22096 VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGI 22155
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
+ AG + + G+P P V W + +E R++ LT+KD
Sbjct: 22156 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-KETDRVSITTTKDRTTLTVKDSM 22214
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDR 3145
D GRY NT G T++ VV R
Sbjct: 22215 RGDSGRYFLTLENTAG-VKTFSVTVVVIGR 22243
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/175 (29%), Positives = 80/175 (45%), Gaps = 26/175 (14%)
Query: 3267 PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIEL 3326
P GL+ + + EG+ + + + YPS VTWYR+ ++ S +T + G L
Sbjct: 897 PTLVSGLKNVTVI-EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 954
Query: 3327 ALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ-------------TSEPRIPPV- 3372
+ D+G +TC+A NE G STS + V +++ T E R
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 3373 -VISPDVPYSKE---------PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ D ++E P FI KP + EG +V+ C+V G+PKP VYW
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/212 (24%), Positives = 88/212 (41%), Gaps = 21/212 (9%)
Query: 3066 ETANLTCSVKGKPVPG--VVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRY 3122
E A LTC V+ + V W K+G +++E G ++ L I ++ D+G Y
Sbjct: 26234 EIAKLTCVVESSVLRAKEVTWYKDGKKLKEN-GHFQFHYSADGTYELKINNLTESDQGEY 26292
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE-------------RSAEVEGDYP-- 3167
CE + G + T + +++ E +K+ R E + P
Sbjct: 26293 VCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPIS 26352
Query: 3168 --PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
P L+D V + + + G P P W KDG+ + + +D+ L
Sbjct: 26353 SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFL 26412
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
EI T+ D G+Y T +N++G+VS C L +
Sbjct: 26413 EIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Score = 67.3 bits (157), Expect = 9e-10
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 3202 YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI 3261
Y+DG ++Y K K D + ++ +D E+ + +C + K
Sbjct: 25122 YEDGVAILYVKDITKLDDGTYRC-KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIK 25180
Query: 3262 RAYVA-------PEFCCGLEPLYK--LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
R PEF PLY + G+ +R + +P VTWY+ G +++P
Sbjct: 25181 RRTDTMRLLERPPEFTL---PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25237
Query: 3313 R-AIMTLDRD-GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T + D G +L + +VTT D YT A N+ G S K+ V T P
Sbjct: 25238 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TLHP--- 25289
Query: 3371 PVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P + PMF R ++E +EG +V E V G P P + W +D
Sbjct: 25290 -----PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKD 25334
Score = 66.9 bits (156), Expect = 1e-09
Identities = 59/215 (27%), Positives = 96/215 (44%), Gaps = 12/215 (5%)
Query: 2931 INISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIG 2990
I + +T K VP+ PG+ V D N VSL+W K + + ++ Y VE +
Sbjct: 16618 IGLPAQTADPIKVAEVPQP-PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVE---MQ 16673
Query: 2991 AEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP 3050
A+ +W E NL QGEEY FRV N G S S ++ + +A D
Sbjct: 16674 AKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEK--GRSDPRSLAVPI-VAKDLV 16730
Query: 3051 EFVDILP--GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
D+ P + G+ + + G+P P + W K+G +++ R+ +
Sbjct: 16731 IEPDVKPAFSSYSVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTT-RINVTDSLDLTT 16789
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
L+IK+ + DD G+Y N G+ + A + +VT
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKT--ASIEIVT 16822
Score = 66.5 bits (155), Expect = 2e-09
Identities = 59/201 (29%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEG--GARW 2997
EP P PG+P ++ + V+L W K P+ T +K+ S+++ RW
Sbjct: 14852 EPMLALDPIDPPGKPVPLNITRHTVTLKWAK--PEYTG---GFKITSYIVEKRDLPNGRW 14906
Query: 2998 VELGITPL--NSFDAFNLKQGEEYHFRVTPRNRYGW-GESSQTSSSIGVGLAGDRPEF-V 3053
++ + + N F L + Y FRV +N G S+ S +I + P+ V
Sbjct: 14907 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV 14966
Query: 3054 DILPGQLKIL-AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
D+ IL AGE L V G+P P + W K+G E+E A ++ + F L K
Sbjct: 14967 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTA-KLEIKIADFSTNLVNK 15025
Query: 3113 DINIDDEGRYSCEATNTHGKA 3133
D D G Y+ ATN G A
Sbjct: 15026 DSTRRDSGAYTLTATNPGGFA 15046
Score = 66.5 bits (155), Expect = 2e-09
Identities = 57/199 (28%), Positives = 81/199 (40%), Gaps = 7/199 (3%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V D + VSLAW K APV Y VE A+
Sbjct: 18505 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGK 18564
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKIL-A 3064
F LK+ EY+FR+ N G GE + S+ + PE +D ++ +L A
Sbjct: 18565 QFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRA 18624
Query: 3065 GETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
T L ++KG+P P V W K G + +TS F L I ++ D GRY+
Sbjct: 18625 SATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFT----MLVIDNVTRFDSGRYN 18680
Query: 3124 CEATNTHGKASTYARLAVV 3142
N G + + + V+
Sbjct: 18681 LTLENNSGSKTAFVNVRVL 18699
Score = 65.7 bits (153), Expect = 3e-09
Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 10/209 (4%)
Query: 2940 EPKPKAVPERIPGEPCVV---DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR 2996
EP + P +P P V D N + L W + + Y VE G++ +
Sbjct: 7080 EPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD---K 7136
Query: 2997 WVELGITPLNS-FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE-FVD 3054
WV G + + L++G+ Y +RV NR G + S+ + I + PE F+D
Sbjct: 7137 WVACGEPVAETKMEVTGLEEGKWYAYRVKTLNRQGASKPSRPTEEIQAVDTQEAPEIFLD 7196
Query: 3055 I-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
+ L L + AG L +V GKP P + W K ++++ R+T + +TI D
Sbjct: 7197 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDK-RITIENVPKKSTVTIVD 7255
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y EA N G+A+ + V+
Sbjct: 7256 SKRSDTGTYIIEAVNVCGRATAVVEVNVL 7284
Score = 65.3 bits (152), Expect = 4e-09
Identities = 107/483 (22%), Positives = 196/483 (40%), Gaps = 51/483 (10%)
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
L + V G ++ L+ I G P+ V W RE + E + ++ + G+ L + +
Sbjct: 903 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSIDFQITFQSGIARLMIREAFA 961
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR---PEKDILIS---VGEDI 2931
+SG +TC A + G V + + V + + + + + EK + S V D
Sbjct: 962 EDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDT 1021
Query: 2932 NISFRTQGEPKPKA--------VPERIPGEPCVVD---GGNNWVSLAWPKSD-PQTTAPV 2979
+++ G +P A V + + G V GGN + W KS P TT
Sbjct: 1022 SLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-- 1079
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
YKV + G + + +T F GE + + RN++ GE+S ++S
Sbjct: 1080 YRYKVS---YNKQTGECKLVISMT-------FADDAGE---YTIVVRNKH--GETSASAS 1124
Query: 3040 SIGVGLAGDRPEFVDILPGQLKIL--AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
+ + ++ ++ Q ++L TA + G+ PG V+ + E E+E
Sbjct: 1125 LL------EEADYELLMKSQQEMLYQTQVTAFVQEPEVGETAPGFVYSEYEKEYEKEQAL 1178
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ + D + ++D+ + K Y R+ T + E D + K
Sbjct: 1179 IRKKM-AKD--TVVVRTYVEDQEFHISSFEERLIKEIEY-RIIKTTLEELLEEDGEEKMA 1234
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNK 3216
F +R+++ R+ V C++ G P PK++WYKDG+ + + +R +
Sbjct: 1235 VDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1294
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
+ + +L I +D G+Y A N G C L V+ AP + LEP+
Sbjct: 1295 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPA-APLGAPTYIPTLEPV 1353
Query: 3277 YKL 3279
++
Sbjct: 1354 SRI 1356
Score = 65.3 bits (152), Expect = 4e-09
Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 6/189 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYR-KKLVDGLITL 2651
P F L + S L C V P V WYR G ++ + LKYR ++ G L
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ + D+ Y N+ G++S +A+L+V + +P T H E+
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGM--GAVHALRGEV 24547
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
V ++ G+P P ITW K I ++G YQ + + +D+G Y A+
Sbjct: 24548 VSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAK 24607
Query: 2771 NSVWTDQIT 2779
N DQ T
Sbjct: 24608 NRFGIDQKT 24616
Score = 64.5 bits (150), Expect = 6e-09
Identities = 31/95 (32%), Positives = 47/95 (49%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + L + T +EG V L C + PTVTWYR +++ + ++ G+ L +
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
A DS ++C+ NE G +STS L V S E
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 991
Score = 64.1 bits (149), Expect = 8e-09
Identities = 54/220 (24%), Positives = 98/220 (44%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G P V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 64.1 bits (149), Expect = 8e-09
Identities = 81/354 (22%), Positives = 136/354 (38%), Gaps = 42/354 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KPV T L D T S K PT W ++G + KY+ G LE
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL--KVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+ SDS Y+CTV+N G++S+S L K EA + T I E
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 26473
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+ + +R + + K++ K +++ L + ++ I + + T E
Sbjct: 26474 EISQKALRSEEI-KMSEAKSQEKLA---------LKEEASKVLISEEVKKSAAT---SLE 26520
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
S+ ++IT + SQ S V T + + T + G +
Sbjct: 26521 KSIVHEEIT-------KTSQASEEVRTHAEIKA--------------FSTQMSINEGQRL 26559
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ I G T V+W+ G +T R V TL + + + G+ TC + +
Sbjct: 26560 VLKANIAGA-TDVKWVLNGVELTN-SEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 26617
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
G V +T+ +L PA + +P I+ G+++ + GEP P+
Sbjct: 26618 EGIVKCQYDLTL--SKELSDAPA-FISQPRSQ-NINEGQNVLFTCEISGEPSPE 26667
Score = 63.7 bits (148), Expect = 1e-08
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 11/188 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
P +P +VD G +++AW K AP+ Y VE W + I L +
Sbjct: 19590 PSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVE---YKKSDDTDW-KTSIQSLRGTEY 19645
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAGE 3066
L G EY FRV N+ G + S +S + P F +D + L + AG
Sbjct: 19646 TISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGA 19705
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
+ +T +G+PVP V+W K ++ A T+ LTI++ N +D G+Y+
Sbjct: 19706 SFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR---TSLTIENANRNDSGKYTLTI 19762
Query: 3127 TNTHGKAS 3134
N AS
Sbjct: 19763 QNVLSAAS 19770
Score = 63.3 bits (147), Expect = 1e-08
Identities = 76/366 (20%), Positives = 142/366 (38%), Gaps = 53/366 (14%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ + A G+P P +W K+G + + S+ G L I + D G
Sbjct: 26366 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG-GFFLEIHKTDTSDSGL 26424
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADA-KLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
Y+C N+ G S+ +L + + + + +A K+ ++++E+ PQ +
Sbjct: 26425 YTCTVKNSAGSVSSSCKLTI---KAIKDTEAQKVSTQKTSEIT----PQ---------KK 26468
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
A ++ + + S K+S K E++ + +K + + A T+L+ V+E
Sbjct: 26469 AVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKKSAATSLEKSIVHEE 26527
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ + + I+A+ ++EG L + A + + V
Sbjct: 26528 ITKTSQASEEVR----THAEIKAFSTQ---------MSINEGQRLVLKANIAG--ATDVK 26572
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
W +GV L S + Q L + + RD G+ TC + + G
Sbjct: 26573 WVLNGVELTNSEEYRYGVSGSDQT-LTIKQASHRDEGILTCISKTKEGIVKCQ------- 26624
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
D T + S P FI +PRS EG V+ CE+ G+P P++ W ++
Sbjct: 26625 YDLTLSKEL-----------SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN 26673
Query: 3421 FLKVRI 3426
L + I
Sbjct: 26674 NLPISI 26679
Score = 62.1 bits (144), Expect = 3e-08
Identities = 32/84 (38%), Positives = 42/84 (50%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E+ + F I++ L + C++ G PLPKI W+KD K+I RYQ +L D
Sbjct: 1239 ESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAEN 2771
G L I PED G YT A N
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASN 1322
Score = 62.1 bits (144), Expect = 3e-08
Identities = 58/205 (28%), Positives = 83/205 (40%), Gaps = 12/205 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P + D L W K +P+L Y VE G A+W + L
Sbjct: 11306 PPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQ---KPGTAQWNRINKDELI 11362
Query: 3007 SFDAFN---LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LK 3061
AF L +G EY FR+ N G GE + + S+ PE +D+ +
Sbjct: 11363 RQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVIT 11422
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+ G+T + VKG+P P + W K G V E+ + + L IK+ D G
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE--LQIKEAVRADHG 11480
Query: 3121 RYSCEATNTHGKASTYARLAVVTDR 3145
+Y A N+ G A A + V DR
Sbjct: 11481 KYIISAKNSSGHAQGSA-IVNVLDR 11504
Score = 62.1 bits (144), Expect = 3e-08
Identities = 53/192 (27%), Positives = 78/192 (40%), Gaps = 11/192 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V D + VSL+W K +P++ Y VE + WV + P N
Sbjct: 13091 PPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVE---VKRADSDNWVRCNL-PQN 13146
Query: 3007 ----SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG--LAGDRPEFVDILPGQL 3060
F+ L + +Y FRV N+ G+ + S L E L L
Sbjct: 13147 LQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGEHDADLRKTL 13206
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+ AG T L VKG+P P + W K + + G + + FD L +++N D G
Sbjct: 13207 ILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKSTDFDTFLRCENVNKYDAG 13265
Query: 3121 RYSCEATNTHGK 3132
+Y N+ GK
Sbjct: 13266 KYILTLENSCGK 13277
Score = 61.3 bits (142), Expect = 6e-08
Identities = 60/227 (26%), Positives = 93/227 (40%), Gaps = 16/227 (7%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+ T L D + EG V LT S+ ++ + V WY L+ + K++ TL +
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300
Query: 2654 LNAVPSD-SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENEL 2711
D EY C N++G +TSA L V A+P+ + HLA+
Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK--RAAPVIKRKIEPLEVALGHLAK--- 4355
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C I+ P + WFK ++I + + + + L I D G YTCKA N
Sbjct: 4356 -FTCEIQSAPNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKASN 4413
Query: 2772 SVWTDQITHFVNFT--GRESQVS---PNVVTAEKTRIARQSLESRRP 2813
+ T + T G E +V P K + +S+ +RP
Sbjct: 4414 EYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP 4460
Score = 61.3 bits (142), Expect = 6e-08
Identities = 58/216 (26%), Positives = 97/216 (44%), Gaps = 13/216 (6%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG-GVYEVTAR 3243
V LT + + +V+WY + + V D++ QD+ +TL I N +D G Y A
Sbjct: 4260 VHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 4317
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+SG + L V K RA AP +EPL ++ G + + +++ P+V W++
Sbjct: 4318 NDSGKTATSAKLTVVK--RA--APVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFK 4372
Query: 3304 DGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG--KVEVIG 3360
G + S + +I + +E+ V D G YTC ASNE G S + V V G
Sbjct: 4373 AGREIYESDKCSIRSSKYISSLEILRTQVV--DCGEYTCKASNEYGSVSCTATLTVTVPG 4430
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
++ +P P + + ++P E +
Sbjct: 4431 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPK 4466
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/204 (26%), Positives = 83/204 (40%), Gaps = 8/204 (3%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELG 3001
K A P P P V D SLAW K + Y VE +G E +
Sbjct: 14170 KDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGT 14229
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQ 3059
+ F +L+ E+Y+FR++ N G GE + + + P+F +D L
Sbjct: 14230 ALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA-VIPDVEIVEREMAPDFELDAELRRT 14288
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDD 3118
L + AG + + +KG+P P V W K+ ++ A T F L I + N D
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFT----LLIIPECNRYD 14344
Query: 3119 EGRYSCEATNTHGKASTYARLAVV 3142
G++ N GK S + + V+
Sbjct: 14345 TGKFVMTIENPAGKKSGFVNVRVL 14368
Score = 60.9 bits (141), Expect = 8e-08
Identities = 73/353 (20%), Positives = 139/353 (39%), Gaps = 21/353 (5%)
Query: 2571 KAFSEARSVISEKRTLSRNSTR--KPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTV 2625
K F E+R V+ +L+ +P F+T + VEG V C V + P V
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 2626 TWYRNGVLLDNKLKYRKKL--VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
W ++GV L +Y+ G L + D+ EY+ V N++G S SA+L
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1127
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
+E +S ++ + + ++ G+ P + + +K+ + QA
Sbjct: 1128 EADYE------LLMKSQQEMLYQTQVTAFVQEPEVGETAPGFVYSEYEKEYEKE---QAL 1178
Query: 2744 YLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRI 2803
+ ED + E + +I + + T E + + EK +
Sbjct: 1179 IRKKMAKDTVVVRTYVEDQEFHISSFEERL-IKEIEYRIIKTTLEELLEED--GEEKMAV 1235
Query: 2804 ARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVF 2862
E+ F + +Y++ G + ++ G P ++ W ++G+ + R F
Sbjct: 1236 DISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDF 1295
Query: 2863 VEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVI 2915
++ G +L + V + G+YT A + GN + + V+P+ G P I
Sbjct: 1296 LQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL-YVEPAAPLGAPTYI 1347
Score = 60.9 bits (141), Expect = 8e-08
Identities = 54/207 (26%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2947 PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESW--LIGAEGGARWVELG 3001
P PG P VVD + ++L W K AP++ Y VE + A W
Sbjct: 11996 PIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCN 12055
Query: 3002 ITPL---NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPG 3058
F +L + +EY FRV +N+ G G ++ +I + PE +D+
Sbjct: 12056 AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPE-IDLDAS 12114
Query: 3059 QLKIL---AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
K++ AG L V+G+P P V W K G + G++ L I +
Sbjct: 12115 MRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQV--DLVDTMAFLVIPNST 12172
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVV 3142
DD G+YS N G+ + + + V+
Sbjct: 12173 RDDSGKYSLTLVNPAGEKAVFVNVRVL 12199
Score = 60.9 bits (141), Expect = 8e-08
Identities = 54/196 (27%), Positives = 85/196 (43%), Gaps = 9/196 (4%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGA-EGGARWVELGITPLNSFD 3009
P P V+D + V L+W K + Y VE + E GI N +
Sbjct: 16344 PNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVNVGEWTMCTPPTGINKTN-IE 16402
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAGET 3067
L + EY+FR+ N+ G GE + I V + P+ +D+ L + I AG +
Sbjct: 16403 VEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGS 16462
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
L +KG+P P V W K E+ + A +TS F L + ++N D G+Y+
Sbjct: 16463 LRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTS----LVLDNVNRYDSGKYTLTL 16518
Query: 3127 TNTHGKASTYARLAVV 3142
N+ G S + + V+
Sbjct: 16519 ENSSGTKSAFVTVRVL 16534
Score = 60.9 bits (141), Expect = 8e-08
Identities = 76/311 (24%), Positives = 121/311 (38%), Gaps = 20/311 (6%)
Query: 2654 LNAVPSDSAEYSC--TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
LN V S +A SC + ++ G + A +KV S E P+ ++ + +
Sbjct: 25037 LNMVVS-AARISCGGAIRSQKGV--SVAKVKV-ASIEIGPVSGQIMHAVGEE----GGHV 25088
Query: 2712 VLECRIRG-QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
C+I ++TW+ +Q+ + +Y+ Y DGV L + + T D GTY CK
Sbjct: 25089 KYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYRCKVV 25147
Query: 2771 NSVWTDQITHFVNFTG-RE--SQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
N D + G RE + K R L R P F L + G
Sbjct: 25148 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25207
Query: 2828 GTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVE--QGLYTLALSDVTETESGLYT 2884
+ V I P V W + G+ + + + E +GLY L ++ VT + YT
Sbjct: 25208 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 25267
Query: 2885 CRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
A + +G A +TV + P D + R + G+ + R G P P
Sbjct: 25268 VVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPP 25327
Query: 2944 KAVPERIPGEP 2954
E+ G+P
Sbjct: 25328 TLKWEK-DGQP 25337
Score = 60.5 bits (140), Expect = 1e-07
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 15/173 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D T G C +S D V WY G L+ K + + TL + +
Sbjct: 5705 LKDVTVTAGETATFDCE-LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 5763
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ E T ++ T ANL F P P FT+ + D VLEC +
Sbjct: 5764 DAGEVQLTAKD----FKTHANL-----FVKEP-PVEFTKPLEDQTVEEGATAVLECEVSR 5813
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAEN 2771
+ K+ WFK+ +I +Y+ +ADG V +L I + TPED TYTC A++
Sbjct: 5814 ENA-KVKWFKNGTEILKSKKYEI--VADGRVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 60.5 bits (140), Expect = 1e-07
Identities = 51/187 (27%), Positives = 83/187 (44%), Gaps = 19/187 (10%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVL 2654
F+ L D+T EG+ L C V S + V W++NG + KY + + DG + L +
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKY-EIVADGRVRKLVIH 5847
Query: 2655 NAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-L 2713
+ P D Y+C ++ TS NL V P F R + D + E E+
Sbjct: 5848 DCTPEDIKTYTCDAKD----FKTSCNLNVVPPH------VEFLRPLTD-LQVREKEMARF 5896
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENS 2772
EC + + K+ WFKD +I +Y ++ G R L I+ +D Y+C+ +
Sbjct: 5897 ECEL-SRENAKVKWFKDGAEIKKGKKYD--IISKGAVRILVINKCLLDDEAEYSCEVRTA 5953
Query: 2773 VWTDQIT 2779
+ +T
Sbjct: 5954 RTSGMLT 5960
Score = 60.5 bits (140), Expect = 1e-07
Identities = 51/175 (29%), Positives = 81/175 (46%), Gaps = 17/175 (9%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN-AVP 2658
LTD E + C +S + V W+++G + KY + G + + V+N +
Sbjct: 5883 LTDLQVREKEMARFECE-LSRENAKVKWFKDGAEIKKGKKY-DIISKGAVRILVINKCLL 5940
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D AEYSC V TS L V EA FT+++ + + + L C +
Sbjct: 5941 DDEAEYSCEVRTAR----TSGMLTVLEE-EA-----VFTKNLANIEVSETDTIKLVCEV- 5989
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENS 2772
+P ++ W+K D++I GRY+ L +G R L I N ED+G Y C+ +S
Sbjct: 5990 SKPGAEVIWYKGDEEIIETGRYE--ILTEGRKRILVIQNAHLEDAGNYNCRLPSS 6042
Score = 60.5 bits (140), Expect = 1e-07
Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 8/183 (4%)
Query: 2962 NWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHF 3021
N +LAW A + Y + S+ + RW E + S LK+G++Y F
Sbjct: 12316 NSATLAWLPPLRDGGAKIDGYII-SYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 12374
Query: 3022 RVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDILPGQLKILAGETANLTCSVKGKPV 3079
RV RN G S + GV A ++ P + ++P Q+ I AG+ + V GKP
Sbjct: 12375 RVAARNAVG---VSLPREAEGVYEAKEQLLPPKI-LMPEQITIKAGKKLRIEAHVYGKPH 12430
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
P W K EV + + + L IKD+ D G YS A N+ G + ++
Sbjct: 12431 PTCKWKKGEDEVVTSSHLAVHKADS-SSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKV 12489
Query: 3140 AVV 3142
V+
Sbjct: 12490 VVM 12492
Score = 60.5 bits (140), Expect = 1e-07
Identities = 54/193 (27%), Positives = 81/193 (41%), Gaps = 9/193 (4%)
Query: 2947 PERIPGEPCVV---DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P PG P VV D VSL W K ++ Y +E G V
Sbjct: 21753 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKTDL-GDWHKVNAEAC 21811
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKI 3062
+ +L+ GEEY FRV+ N G G+S + + +I PE +D Q +
Sbjct: 21812 VKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHV 21871
Query: 3063 L-AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AG + L + +G+P P VW K + A T+ + F LT+++ N +D G+
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT--DSFS-TLTVENCNRNDAGK 21928
Query: 3122 YSCEATNTHGKAS 3134
Y+ N G S
Sbjct: 21929 YTLTVENNSGSKS 21941
Score = 60.1 bits (139), Expect = 1e-07
Identities = 43/157 (27%), Positives = 69/157 (43%), Gaps = 8/157 (5%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
R+ +S K L+ S P + D T G +L+C ++ P + WYR G L
Sbjct: 24021 RTAMSIKTKLT--SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 24078
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
KY+ TL V+ D Y+C NE G + TS+ L + + + P P
Sbjct: 24079 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP-- 24136
Query: 2697 TRSIRDTFHLA-ENELVLECRIRGQPLPKITWFKDDK 2732
+++ ++ A + L L G+P+P +TWF K
Sbjct: 24137 ---LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK 24170
Score = 58.8 bits (136), Expect = 3e-07
Identities = 40/143 (27%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V +P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 58.8 bits (136), Expect = 3e-07
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 18/149 (12%)
Query: 3273 LEPL-YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P+ +K EG R V P W+ DG ++ + + DG L +
Sbjct: 1415 LKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPA 1474
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
T D+G +T A N GR+S + VI T + E ++ +PMF+ K +
Sbjct: 1475 TPSDSGEWTVVAQNRAGRSS----ISVILTVEAVEHQV-------------KPMFVEKLK 1517
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ +EG + ++ G+P PD+ WL++
Sbjct: 1518 NVNIKEGSRLEMKVRATGNPNPDIVWLKN 1546
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/277 (24%), Positives = 115/277 (41%), Gaps = 32/277 (11%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRYS 3123
G A+ V GKP P W KNG ++E + R+ + + C L I+D+ +D
Sbjct: 2046 GSDAHFRVRVVGKPDPECEWYKNGVKIER-SDRIYWYWPEDNVCELVIRDVTAEDSASIM 2104
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
+A N G+ S++A L V AK + E++ + +++ AT+
Sbjct: 2105 VKAINIAGETSSHAFLLV---------QAKQLITFTQELQD-------VVAKEKDTMATF 2148
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C+ P KV WYKDG EV + + D + H L I + D Y
Sbjct: 2149 E----CET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+ V L+V+ + EF L+ + ++ E + +V ++ WY
Sbjct: 2204 EDEN-VKTTAKLIVEGAV-----VEFVKELQDI-EVPESYSGELECIVSP-ENIEGKWYH 2255
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
+ V L+ + + +T R G+ L + VT D G Y+
Sbjct: 2256 NDVELKSNGKYTIT-SRRGRQNLTVKDVTKEDQGEYS 2291
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 22/150 (14%)
Query: 3109 LTIKDINIDD-EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I +N +D +G Y CEA N GK +T A+L VV +R+A
Sbjct: 4298 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV--------------KRAA------- 4336
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P ++ V + + TC++ +P + W+K G E+ + + + +LEI
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
T + D G Y A N G+VSC L V
Sbjct: 4397 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 58.8 bits (136), Expect = 3e-07
Identities = 55/208 (26%), Positives = 92/208 (44%), Gaps = 8/208 (3%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP P PG+P V++ N V+L W + + Y VE + ++ +
Sbjct: 13769 EPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANH 13828
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW-GESSQTSSSIGVGLAGDRPEFV--DIL 3056
+ + P +F +L +G +Y FR+ +N G S+++ +I + P V +
Sbjct: 13829 VNV-PECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTI 13887
Query: 3057 PGQLKILAGETANLTC-SVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
L I AG+T L S+ GKP+P W K G ++ + ++TS LTIK
Sbjct: 13888 KDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITS--TPTSSMLTIKYA 13945
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y+ ATN G + ++ V+
Sbjct: 13946 TRKDAGEYTITATNPFGTKVEHVKVTVL 13973
Score = 58.8 bits (136), Expect = 3e-07
Identities = 54/215 (25%), Positives = 92/215 (42%), Gaps = 14/215 (6%)
Query: 2939 GEPKPKAV------PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLI 2989
GEP P V P PG P +VD N ++LAW K + +L Y VE
Sbjct: 17405 GEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA 17464
Query: 2990 GAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR 3049
E + F+ L + +EY RV N+ G GE++ ++ +
Sbjct: 17465 DEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEA 17524
Query: 3050 PEF-VDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
PE +D L + + AG +A + KG+P+P + W + E ++ ++ N
Sbjct: 17525 PELDLDSELRKGIVVRAGGSARIHIPFKGRPMPEITWSREEGEFTDKV-QIEKGVNYTQ- 17582
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L+I + + +D G+Y + N+ G S + + V+
Sbjct: 17583 -LSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVL 17616
Score = 58.0 bits (134), Expect = 6e-07
Identities = 51/206 (24%), Positives = 82/206 (39%), Gaps = 6/206 (2%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP + P PG +VD N ++ W K + + + Y VE + +G +W
Sbjct: 18791 EPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVE---MQTKGSEKWST 18847
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
L GEEY FRV N G + Q + +P V++
Sbjct: 18848 CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS-VELPFHT 18906
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ A E + KG+P V W K+G ++E R+ + L+IK+ + +D
Sbjct: 18907 FNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETT-RVNVSSSKTVTSLSIKEASKEDV 18965
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDR 3145
G Y +N+ G + T +V DR
Sbjct: 18966 GTYELCVSNSAG-SITVPITIIVLDR 18990
Score = 58.0 bits (134), Expect = 6e-07
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 7/184 (3%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRV 3023
VSL W K + + ++ Y VE+ +G WV+ + L++ EY FRV
Sbjct: 19894 VSLTWLKPEHDGGSRIVHYVVEAL---EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRV 19950
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LKILAGETANLTCSVKGKPVPG 3081
N+ G + + + + + PE + P + + AG + + GKP+P
Sbjct: 19951 FAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPK 20010
Query: 3082 VVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
V ++G ++ R ++ + + +K+ D GRY A N+ G + + V
Sbjct: 20011 VTLSRDGVPLKATM-RFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINI-V 20068
Query: 3142 VTDR 3145
V DR
Sbjct: 20069 VLDR 20072
Score = 57.2 bits (132), Expect = 1e-06
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 3/201 (1%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELG 3001
+P VPER P + V + N V+L W + ++ Y +ES LIG E +
Sbjct: 10215 EPITVPER-PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10273
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLK 3061
+ + LK+G+ Y +RV+ N G G+ S + I P +L
Sbjct: 10274 LLS-RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLT 10332
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GE LT GKP P V W K+ +V E+ R + L D G+
Sbjct: 10333 IRVGEAFALTGRYSGKPKPKVSWFKDEADVLED-DRTHIKTTPATLALEKIKAKRSDSGK 10391
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y N+ G + ++ VV
Sbjct: 10392 YCVVVENSTGSRKGFCQVNVV 10412
Score = 56.8 bits (131), Expect = 1e-06
Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD +S V P + W+ +GV L PS D D L + D G YTC
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTC 3529
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM---FIRKPRSSEAREG 3398
ASN+ G+ S +++ + + ++ + P F+++ + +G
Sbjct: 3530 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3589
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
I E VVG+P P V W ++
Sbjct: 3590 LPAIFEYTVVGEPAPTVTWFKE 3611
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/263 (23%), Positives = 103/263 (39%), Gaps = 17/263 (6%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG P V+D + +S+AW K + + Y VE L + S+
Sbjct: 15262 PGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTI 15321
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDI---LPGQLKILAG 3065
L + +EY R+ N G GE + G A DR P +++ L + I A
Sbjct: 15322 TGLTENQEYKIRIYAMNSEGLGEPALVP---GTPKAEDRMLPPEIELDADLRKVVTIRAC 15378
Query: 3066 ETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
T L +KG+P P V W + +G +++ + S + L + ++N D G+Y
Sbjct: 15379 CTLRLFVPIKGRPDPEVKWARDHGESLDKASIESASSYT----LLIVGNVNRFDSGKYIL 15434
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFT---MRLRDRRVQA 3181
N+ G S + + V+ D D K+K V + P ++++ V+
Sbjct: 15435 TVENSSGSKSAFVNVRVL-DTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEK 15493
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKD 3204
R + + K SW D
Sbjct: 15494 RESTRKAYSTVATNCHKTSWKVD 15516
Score = 56.8 bits (131), Expect = 1e-06
Identities = 52/192 (27%), Positives = 78/192 (40%), Gaps = 8/192 (4%)
Query: 2951 PGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS 3007
PG P + D + ++L W K + V Y VE E G
Sbjct: 20670 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTE 20729
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAG 3065
+ NLK G Y+FRV+ N G GE + + + + PE +D+ L + AG
Sbjct: 20730 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20789
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
E + KG+P P V W K+ + +A R + + LTI + +D G+Y
Sbjct: 20790 EDVQVLIPFKGRPPPTVTWRKDEKNLGSDA-RYSIENTDSSSLLTIPQVTRNDTGKYILT 20848
Query: 3126 ATNTHG--KAST 3135
N G K+ST
Sbjct: 20849 IENGVGEPKSST 20860
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/199 (24%), Positives = 79/199 (39%), Gaps = 22/199 (11%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
Q+ I G+ L ++ G V W+ NG E+ +G D LTIK + D
Sbjct: 26550 QMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSE-EYRYGVSGSDQTLTIKQASHRD 26606
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
EG +C + G + D L +E S P F + R +
Sbjct: 26607 EGILTCISKTKEGIVKC-------------QYDLTLSKELSDA------PAFISQPRSQN 26647
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ V TC++ G P P++ W+K+ + + + ++LEI ++ D G Y
Sbjct: 26648 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 26707
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
+ A+N G S L+V
Sbjct: 26708 TIKAKNFRGQCSATASLMV 26726
Score = 56.4 bits (130), Expect = 2e-06
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 11/178 (6%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVLNAVPSDSA 2662
T V+G + L+C + D V W ++G ++ K V GL+ L + +A +D+
Sbjct: 4726 TVVKGQPLYLSCELNKERD--VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAG 4783
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+ TVEN N + S+ +KV I + IRD + + C I +
Sbjct: 4784 TYTVTVENANN-LECSSCVKV-----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDT 4836
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P I WFK +IP++ + L DG L I N PED Y + E + ++T
Sbjct: 4837 PNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLT 4894
Score = 56.4 bits (130), Expect = 2e-06
Identities = 62/312 (19%), Positives = 122/312 (39%), Gaps = 24/312 (7%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
D P F+ P I G+ TC + G+P P + W KN + + S+
Sbjct: 26635 DAPAFIS-QPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV-Y 26692
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I++ ++ D G+Y+ +A N G+ S A L V+ + L+ ++G +
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 26752
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
Q ++++ + +A++ S + + + E F +E+
Sbjct: 26753 SQ-SVQMSASKQEASFS--------SFSSSSASSMTEMKFASMSAQSMSSMQESF--VEM 26801
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+ ++ G+ +T +S + G+ +GI P L + EG L +
Sbjct: 26802 SSSSF--MGISNMTQLESSTSKMLKAGI---RGI-----PPKIEALPSDISIDEGKVLTV 26851
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR-DGQIELALAAVTTRDAGVYTCTASNE 3346
+ P+ VTW G ++ + ++ D L + V +D G+YT + NE
Sbjct: 26852 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 26911
Query: 3347 VGRASTSGKVEV 3358
G S + + +
Sbjct: 26912 FGSDSATVNIHI 26923
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 8/194 (4%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDEQFHTLE 3226
P+ R++ + V +V+G P P+ WYK+G ++ R Y ++ L
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I +D V A N +G S H L+V +A F L+ + E D +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQLITFTQELQDVV-AKEKDTMA 2146
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ P V V WY+DG+ + + M DR L++ + T DA Y+C E
Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHF-LSILTIDTSDAEDYSCVLV-E 2204
Query: 3347 VGRASTSGKVEVIG 3360
T+ K+ V G
Sbjct: 2205 DENVKTTAKLIVEG 2218
Score = 56.0 bits (129), Expect = 2e-06
Identities = 59/266 (22%), Positives = 99/266 (37%), Gaps = 10/266 (3%)
Query: 2661 SAEYSCTVENENGAISTSANLKVYPS---FEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
SAE + NE + + VYP+ E P F + + + + L +
Sbjct: 3423 SAELQLSKINET--LELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTV 3480
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
G P PKI WF + + Y+ + D + + ED G YTC A N
Sbjct: 3481 IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL-EDEGEYTCMASNDYGKTI 3539
Query: 2778 ITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIR 2837
+ ++ + + + + PHF L + A+G + +
Sbjct: 3540 CSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVV 3599
Query: 2838 GCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P V W +E + + T VY + G T ++D +SGLY C+A + G
Sbjct: 3600 GEPAPTVTWFKENKQLCTSVYYTI-IHNPNGSGTFIVNDPQREDSGLYICKAENMLGEST 3658
Query: 2896 MNAAITV-VQPSDLDGKPAVIVGRPE 2920
A + V ++ +D+ P PE
Sbjct: 3659 CAAELLVLLEDTDMTDTPCKAKSTPE 3684
Score = 56.0 bits (129), Expect = 2e-06
Identities = 57/212 (26%), Positives = 88/212 (41%), Gaps = 22/212 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP-- 3004
P P P V D + +SL W +P+ Y VE + EG W +
Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVE---MQEEGTTDWKRVNEPDKL 9263
Query: 3005 LNSFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE-FVDI-LPGQL 3060
+ + + NLK+ +Y FRV N G E S T+ I + PE F+DI L
Sbjct: 9264 ITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCL 9323
Query: 3061 KILAGETANLTCSVKGKPVPGVVW---------MKNG-HEVEEEAGRMTSQFNGFDCCLT 3110
AG + +KG+P P W MK+G H++ E+A T++ + +
Sbjct: 9324 VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS---VII 9380
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I + G+YS A N G+ + R+ V+
Sbjct: 9381 IPECKRSHTGKYSITAKNKAGQKTANCRVKVM 9412
Score = 55.6 bits (128), Expect = 3e-06
Identities = 53/207 (25%), Positives = 86/207 (41%), Gaps = 13/207 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP + P ++D + VSLAWPK + + Y +E+ +G +W
Sbjct: 14460 EPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEA---QRKGSDQWTH 14516
Query: 3000 LGITPLNSFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP 3057
IT + + NL +GEEY F+V N G + + S + V PE +D+
Sbjct: 14517 --ITTVKGLECVVRNLTEGEEYTFQVMAVNSAG-RSAPRESRPVIVKEQTMLPE-LDLRG 14572
Query: 3058 GQLKIL---AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
K++ AG+ + V G+P P V W K G ++ ++ R+ + L I +
Sbjct: 14573 IYQKLVIAKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINEC 14631
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAV 3141
D G Y A N G+ + V
Sbjct: 14632 VRSDSGPYPLTARNIVGEVGDVITIQV 14658
Score = 55.2 bits (127), Expect = 4e-06
Identities = 89/395 (22%), Positives = 151/395 (38%), Gaps = 56/395 (14%)
Query: 3078 PVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
P V W+ +G +E RM ++F G+ C L D G +C ATN +G T
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEF-GY-CSLDYGVAYSRDSGIITCRATNKYGTDHTS 1743
Query: 3137 ARLAVVTDRTVWEA----DAKLKRERSAEVEG----------------DYPPQFTMRLRD 3176
A L V ++++ E + + +R E+E P +
Sbjct: 1744 ATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEP 1803
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
RV R C+V G P PKV+WY +G +++ +R + + + H L+I D G
Sbjct: 1804 VRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIHYLDIVDCKSYDTG 1862
Query: 3237 VYEVTARNNSGAVSCHCGLVVD--KGIRAYV--APEFCCGLEPLYKLHEGDELRISAVVE 3292
+VTA N G + L + + R+ + APE P + +HE +L+ V +
Sbjct: 1863 EVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPE----PRPEFHVHEPGKLQFE-VQK 1917
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV-GRAS 3351
V T ++ V+L+ + R + EL + G Y + E+ R
Sbjct: 1918 VDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKK 1977
Query: 3352 TSGKVEVIG-------------TDQ-----TSEPRIPPVVISPD----VPYSKEPMFIRK 3389
E++ T++ E +I PD P + P +
Sbjct: 1978 DESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFER 2037
Query: 3390 PRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+S +G VVG P P+ W ++ +K+
Sbjct: 2038 IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2072
Score = 55.2 bits (127), Expect = 4e-06
Identities = 29/90 (32%), Positives = 43/90 (47%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P + +QA +++ VIG P P +SW KDGE + R N + L I
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
N DD G Y VTA N++G + + ++V
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 55.2 bits (127), Expect = 4e-06
Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
TLS+ + P F + + EG V TC + P + W++N + +
Sbjct: 26628 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 26687
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT 2703
+ +LE+ NA SDS +Y+ +N G S +A+L V P E P R+ DT
Sbjct: 26688 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE-EPSREVVLRTSGDT 26745
Score = 54.8 bits (126), Expect = 5e-06
Identities = 61/256 (23%), Positives = 99/256 (38%), Gaps = 25/256 (9%)
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAG 3065
NS+ L++G Y+FRVT N YG G +QT+ I V P + + ++
Sbjct: 16593 NSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSL 16652
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
K + +V M+ H E E R+ S I ++ +E +
Sbjct: 16653 SWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKS------LQAVITNLTQGEEYLFRV 16706
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G++ + + + + +E D P F+ VQ
Sbjct: 16707 VAVNEKGRSDPRSLAVPIVAKDL-------------VIEPDVKPAFS----SYSVQVGQD 16749
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+++ + G P P ++W KDG + R N TL I T+ DDGG Y +T N
Sbjct: 16750 LKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVAN 16809
Query: 3245 NSGAVSCHCGLV-VDK 3259
G + +V +DK
Sbjct: 16810 VVGQKTASIEIVTLDK 16825
Score = 54.4 bits (125), Expect = 7e-06
Identities = 32/128 (25%), Positives = 51/128 (39%), Gaps = 1/128 (0%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + + GE+A +C G+PVP V W++ G +V + R + I +
Sbjct: 26070 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKG-QVLSTSARHQVTTTKYKSTFEISSVQA 26128
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DEG YS N+ GK L + R +A R +S E P R
Sbjct: 26129 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRV 26188
Query: 3177 RRVQATYP 3184
+ + ++P
Sbjct: 26189 KSPEPSHP 26196
Score = 53.6 bits (123), Expect = 1e-05
Identities = 56/229 (24%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+E EG P F + + + L+ VIG P PK+ W+ +G + D
Sbjct: 3450 SEKEGT-GPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 3508
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--------DKGIRAYVA----- 3266
H+L I T L+D G Y A N+ G C L + D + VA
Sbjct: 3509 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3568
Query: 3267 ------PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR 3320
P F L+P+ + +G V P+ VTW+++ +L S + +
Sbjct: 3569 LGGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 3627
Query: 3321 DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI--GTDQTSEP 3367
+G + D+G+Y C A N +G ++ + ++ V+ TD T P
Sbjct: 3628 NGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3676
Score = 53.6 bits (123), Expect = 1e-05
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 6/151 (3%)
Query: 2947 PERIPGEPCVVDGGN---NWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P++ P P V+ N +++ W + ++ Y +E G E R E +
Sbjct: 8079 PKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNE-HLV 8137
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL 3063
P+ ++ A L++G+EY FRV N G E S+ + D P+ IL L++
Sbjct: 8138 PILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV--ILRTSLEVK 8195
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
G+ L S+ G P P + W+K+ + + E
Sbjct: 8196 RGDEIALDASISGSPYPTITWIKDENVIVPE 8226
Score = 53.6 bits (123), Expect = 1e-05
Identities = 50/195 (25%), Positives = 78/195 (40%), Gaps = 6/195 (3%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT-PLNSFD 3009
P P +D N V L W + +L Y VE +G E R + P +
Sbjct: 10619 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10678
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFV-DI-LPGQLKILAGET 3067
L+ G+ Y FRV N G + + + V + PE + D + + I G+T
Sbjct: 10679 VTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDT 10738
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L+ +KG P P V W K + +A R+ G L I++ +D G YS
Sbjct: 10739 LRLSAIIKGVPFPKVTWKKEDRDAPTKA-RIDVTPVGSK--LEIRNAAHEDGGIYSLTVE 10795
Query: 3128 NTHGKASTYARLAVV 3142
N G + ++ V+
Sbjct: 10796 NPAGSKTVSVKVLVL 10810
Score = 53.6 bits (123), Expect = 1e-05
Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 11/170 (6%)
Query: 2958 DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGE 3017
D V L+W K D + + Y VE +G W GI+ + LK+
Sbjct: 20976 DSTKTSVILSWTKPDFDGGSVITEYVVER---KGKGEQTWSHAGISKTCEIEVSQLKEQS 21032
Query: 3018 EYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI--LPG-QLKILAGETANLTCSV 3074
FRV +N G + T I V PE VD+ +PG Q+ + G +L
Sbjct: 21033 VLEFRVFAKNEKGLSDPV-TIGPITVKELIITPE-VDLSDIPGAQVTVRIGHNVHLELPY 21090
Query: 3075 KGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
KGKP P + W+K+G ++E E R + N L+IK+ + G+Y+
Sbjct: 21091 KGKPKPSISWLKDGLPLKESEFVRFSKTEN--KITLSIKNAKKEHGGKYT 21138
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/96 (30%), Positives = 40/96 (41%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
D+ P+ T+R+R RV R V P +V WY +G E+ + + T
Sbjct: 25874 DHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKG 3260
LEI + DD G Y N G S + L V G
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGG 25969
Score = 52.8 bits (121), Expect = 2e-05
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query: 2568 HRSKAFSEARSVISEKRTLSRNSTRKPVFSTF----LT---DRTAVEGSRVKLTCSVISS 2620
+ A +E +S E+++L ST + + +T LT T EG + +C
Sbjct: 26031 YEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGE 26090
Query: 2621 SDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENG 2673
PTVTW R G +L +++ T E+ + SD YS VEN G
Sbjct: 26091 PVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 26143
Score = 52.4 bits (120), Expect = 3e-05
Identities = 52/183 (28%), Positives = 80/183 (43%), Gaps = 15/183 (8%)
Query: 2965 SLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVT 3024
S+ W K + ++ Y V+ + E +W + + + A +L +G+EY FRV+
Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVD--FLTEEN--KWQRVMKSLSLQYSAKDLTEGKEYTFRVS 13459
Query: 3025 PRNRYGWGESSQTSSSIGVGLAGDRPEFVDI-LPG--QLKILAGETAN--LTCSVKGKPV 3079
N G G T S I V +A D D+ L G L LA E +N L +KGKP
Sbjct: 13460 AENENGEG----TPSEITV-VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13514
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
P V W K G + R++ + + + L + D D G+Y+ N G +
Sbjct: 13515 PSVSW-KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISI 13573
Query: 3140 AVV 3142
VV
Sbjct: 13574 KVV 13576
Score = 52.4 bits (120), Expect = 3e-05
Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 14/141 (9%)
Query: 3230 TNLDDGGVYE--VTARNNSGAVSC---HCGLVV--DKGIRAYV--APEFCCGLEPLYKLH 3280
T L G YE + ARN G +S G+++ D+ + V PE+ GL +
Sbjct: 21419 TGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLI----IK 21474
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
G+ LRI A+V+ P VTW++DGV + R + + G L + T GVYT
Sbjct: 21475 SGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNMEITNVLGSTSLFVRDATRDHRGVYT 21533
Query: 3341 CTASNEVGRASTSGKVEVIGT 3361
A N G A KV+V T
Sbjct: 21534 VEAKNASGSAKAEIKVKVQDT 21554
Score = 52.0 bits (119), Expect = 4e-05
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG++L I A P V+W++DG ++ S R M D L + DAG+YT
Sbjct: 7903 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISA-HLEVPKSVRADAGIYT 7961
Query: 3341 CTASNEVGRASTSGKVEVIG 3360
T N++G A+ S V+VIG
Sbjct: 7962 ITLENKLGSATASINVKVIG 7981
Score = 51.6 bits (118), Expect = 5e-05
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK-Y 2640
+K LS + +F + +T +GS V+ DP WY+NGV ++ + Y
Sbjct: 2021 DKIELSPSMEAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSI 2700
D + L + + DSA N G S+ A L V +A + TFT+ +
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQL-ITFTQEL 2134
Query: 2701 RDTFHLAENEL-VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+D ++ + EC +P K+ W+KD ++ +Y+ + V L+I
Sbjct: 2135 QDVVAKEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSDRKVHFLSILTIDT 2192
Query: 2760 EDSGTYTC 2767
D+ Y+C
Sbjct: 2193 SDAEDYSC 2200
Score = 51.2 bits (117), Expect = 6e-05
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T + +KP + +EG + C V P V WY NG L+ ++R +
Sbjct: 1786 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR- 1844
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
DG+ L++++ D+ E T EN G I L++
Sbjct: 1845 YDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 50.8 bits (116), Expect = 8e-05
Identities = 78/344 (22%), Positives = 137/344 (39%), Gaps = 47/344 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AGETA C + + +P V W G ++E + ++ + G LT++D+ ++D G
Sbjct: 5710 VTAGETATFDCELSYEDIP-VEWYLKGKKLEP-SDKVVPRSEGKVHTLTLRDVKLEDAG- 5766
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
E T T+A L V + P +FT L D+ V+
Sbjct: 5767 ---EVQLTAKDFKTHANLFV----------------------KEPPVEFTKPLEDQTVEE 5801
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
L C+V KV W+K+G E++ K+ D + L I +D Y
Sbjct: 5802 GATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCD 5860
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A++ SC+ +V EF L L ++ E + R + + + V W
Sbjct: 5861 AKDFK--TSCNLNVVPPH-------VEFLRPLTDL-QVREKEMARFECEL-SRENAKVKW 5909
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++DG ++ ++ + + + L + D Y+C EV A TSG + V+
Sbjct: 5910 FKDGAEIKKGKKYDI-ISKGAVRILVINKCLLDDEAEYSC----EVRTARTSGMLTVLEE 5964
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA-REGDTVIIE 3404
+ + + +S + K + KP + +GD IIE
Sbjct: 5965 EAVFTKNLANIEVS-ETDTIKLVCEVSKPGAEVIWYKGDEEIIE 6007
Score = 50.8 bits (116), Expect = 8e-05
Identities = 27/80 (33%), Positives = 41/80 (51%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G+ V L +V PTV+W ++G LL + + L TLE+ + DS +
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGD 12868
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y+ T EN +G+ S + LKV
Sbjct: 12869 YTITAENSSGSKSATIKLKV 12888
Score = 50.8 bits (116), Expect = 8e-05
Identities = 75/312 (24%), Positives = 120/312 (38%), Gaps = 33/312 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P +P V + N +++W + + + Y VE + RWV TP++
Sbjct: 14074 PPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVER---REKKSLRWVRAIKTPVS 14130
Query: 3007 SF--DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
L++G Y FRV+ NR G G S+ S S+ + A P P +
Sbjct: 14131 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPG-----PPSNPHVT 14185
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVE-EEAG--RMTSQFNGFDCCLT---IKDINIDD 3118
T GKP G+ VE ++ G G +T + D+ +
Sbjct: 14186 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKE 14245
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
+ + A N G AV+ D + ++RE + + E D + T+ +R
Sbjct: 14246 KYNFRISAINDAGVGEP----AVIPDVEI------VEREMAPDFELDAELRRTLVVR--- 14292
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
A +R+ + G P P+V+W KD + R N E F L I N D G +
Sbjct: 14293 --AGLSIRIFVPIKGRPAPEVTWTKD--NINLKNRANIENTESFTLLIIPECNRYDTGKF 14348
Query: 3239 EVTARNNSGAVS 3250
+T N +G S
Sbjct: 14349 VMTIENPAGKKS 14360
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/249 (22%), Positives = 107/249 (42%), Gaps = 32/249 (12%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
++ L +G EY FRV N YG GE ++T+ + A P+ ++I+ +
Sbjct: 14428 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMD-----ITKS 14482
Query: 3067 TANLTCSVK----GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
T +L G + G V ++ + ++ +T+ G +C ++++ +E +
Sbjct: 14483 TVSLAWPKPKHDGGSKITGYV-IEAQRKGSDQWTHITT-VKGLEC--VVRNLTEGEEYTF 14538
Query: 3123 SCEATNTHGK-ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
A N+ G+ A +R +V ++T+ ++ G Y + D
Sbjct: 14539 QVMAVNSAGRSAPRESRPVIVKEQTMLP---------ELDLRGIYQKLVIAKAGDN---- 14585
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEV 3240
+++ V+G P P V+W K G++++ +R ++ T L I D G Y +
Sbjct: 14586 ---IKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 14641
Query: 3241 TARNNSGAV 3249
TARN G V
Sbjct: 14642 TARNIVGEV 14650
Score = 50.8 bits (116), Expect = 8e-05
Identities = 53/199 (26%), Positives = 82/199 (41%), Gaps = 23/199 (11%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--FDAFNL 3013
+ D N VSL+W + + + Y VE + +G RW + T + F L
Sbjct: 20279 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDL-PDG--RWTKASFTNVTETQFTISGL 20335
Query: 3014 KQGEEYHFRVTPRNRYGWGESSQTSSSIGV--------GLAGDRP-EFVDILPGQLKILA 3064
Q +Y FRV RN G S S +G G D P E+ +++ K A
Sbjct: 20336 TQNSQYEFRVFARNAVG--SISNPSEVVGPITCIDSYGGPVIDLPLEYTEVV----KYRA 20389
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD-CCLTIKDINIDDEGRYS 3123
G + L + GKP P + W K+ E++ A + N D + IKD + + G Y
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNA--LVCVENTTDLASILIKDADRLNSGCYE 20447
Query: 3124 CEATNTHGKASTYARLAVV 3142
+ N AS R+ ++
Sbjct: 20448 LKLRNAMASASATIRVQIL 20466
Score = 50.8 bits (116), Expect = 8e-05
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EE 3093
S TS + G+ G P+ ++ LP + I G+ + C+ G+P P V W G ++ +
Sbjct: 26817 SSTSKMLKAGIRGIPPK-IEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 26875
Query: 3094 EAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
E GR + L I D+ D G Y+ N G S + +
Sbjct: 26876 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 50.4 bits (115), Expect = 1e-04
Identities = 80/330 (24%), Positives = 123/330 (37%), Gaps = 47/330 (14%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTT--APVLAYKVESWLIGAEGGARWVEL 3000
P VP+ P P +VD ++ VSL W +DP+ T +P+ Y +E W
Sbjct: 13675 PFDVPDA-PPPPNIVDVRHDSVSLTW--TDPKKTGGSPITGYHLE---FKERNSLLWKRA 13728
Query: 3001 GITPLN--SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL----AGDRPEFVD 3054
TP+ F L +G EY FRV N G G+ S S + V L +PE ++
Sbjct: 13729 NKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPV-VALDPIDPPGKPEVIN 13787
Query: 3055 ILPGQLKILAGETA-----NLT-CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
I + ++ E LT V+ + +P WMK H N +C
Sbjct: 13788 ITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANH------------VNVPECA 13835
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYAR-LAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
T+ D+ + + A NT G S + + + +EA + ++
Sbjct: 13836 FTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP-------TIVLDPTIK 13888
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
T++ D V ++G P PK SW K G+++ L I
Sbjct: 13889 DGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTI 13942
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
D G Y +TA N G H + V
Sbjct: 13943 KYATRKDAGEYTITATNPFGTKVEHVKVTV 13972
Score = 50.0 bits (114), Expect = 1e-04
Identities = 56/206 (27%), Positives = 89/206 (43%), Gaps = 33/206 (16%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
E +TS+ + V G R +F+ L Q + GETA C + + + VVW KN ++
Sbjct: 5062 EGKKTSARLFV--TGIRLKFMSPLEDQT-VKEGETATFVCELSHEKMH-VVWFKNDAKLH 5117
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
+ S G L +K++ +DD + + + S+ A+L V+ EAD
Sbjct: 5118 TSRTVLISS-EGKTHKLEMKEVTLDDISQIKAQVK----ELSSTAQLKVL------EAD- 5165
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
P FT++L D+ + L C+V P V W+KDGEE+V
Sbjct: 5166 ---------------PYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSP 5208
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ + D L+I +L D G Y
Sbjct: 5209 KYSIKADGLRRILKIKKADLKDKGEY 5234
Score = 49.2 bits (112), Expect = 3e-04
Identities = 44/186 (23%), Positives = 76/186 (40%), Gaps = 31/186 (16%)
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED-SGTYTCKAENSVWTDQITHFV 2782
++ W+ ++K +PSD +++ L ID ED G Y C+A N
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQ-DQNTYTLVIDKVNTEDHQGEYVCEALND---------- 4319
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
S T+ K + +++ P + +VA G EI+ P
Sbjct: 4320 ---------SGKTATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEIQSAPNV 4366
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLY--TLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
R +W + GR E+Y + + + Y +L + + G YTC+A + +G+V A
Sbjct: 4367 RFQWFKAGR---EIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4423
Query: 2900 ITVVQP 2905
+TV P
Sbjct: 4424 LTVTVP 4429
Score = 49.2 bits (112), Expect = 3e-04
Identities = 48/184 (26%), Positives = 84/184 (45%), Gaps = 17/184 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT-L 2651
K + LT+ V GS C ++S S TW ++G + K+R + DG L
Sbjct: 4622 KEIKDIILTESEFV-GSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRF-IADGKDRKL 4678
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE- 2710
+++ SD+ EY+C + N +++A L V +P F +++ + + + +
Sbjct: 4679 HIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV------EELPVRFVKTLEEEVTVVKGQP 4732
Query: 2711 LVLECRIRGQPLPKITWFKDDK-QIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCK 2768
L L C + + + W KD K + GR + G+ R L I++ D+GTYT
Sbjct: 4733 LYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVI--GLMRALTINDADDTDAGTYTVT 4788
Query: 2769 AENS 2772
EN+
Sbjct: 4789 VENA 4792
Score = 49.2 bits (112), Expect = 3e-04
Identities = 51/191 (26%), Positives = 71/191 (37%), Gaps = 12/191 (6%)
Query: 2962 NWVSLAWPKSDPQTTAPVLAYKVE--SWLIGAEGGARWVELGITPLNS--FDAFNLKQGE 3017
N V L+W +PV Y VE +W W + + F +L +G
Sbjct: 9529 NTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGG 9588
Query: 3018 EYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGK 3077
EY FRV N G + S T D P +D L +++ G N+ +KG
Sbjct: 9589 EYEFRVKAVNAAGVSKPSATVGPCDCQRP-DMPPSID-LKEFMEVEEGTNVNIVAKIKGV 9646
Query: 3078 PVPGVVWMKNGHEV--EEEAGRMTSQFNGF----DCCLTIKDINIDDEGRYSCEATNTHG 3131
P P + W K + +E + N C L I D G Y+ A N G
Sbjct: 9647 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 9706
Query: 3132 KASTYARLAVV 3142
AS RL V+
Sbjct: 9707 TASKEMRLNVL 9717
Score = 49.2 bits (112), Expect = 3e-04
Identities = 55/252 (21%), Positives = 106/252 (42%), Gaps = 24/252 (9%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
+F NL++G Y+FRV N YG G ++T+ + V + P + PG++ ++ +
Sbjct: 18759 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS---EPP----LPPGRVTLV--D 18809
Query: 3067 TANLTCSVKG-KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
T ++K KP G+ VE + T + C +K + G
Sbjct: 18810 VTRNTATIKWEKPESDGGSKITGYVVEMQ----TKGSEKWSTCTQVKTLEATISGL---- 18861
Query: 3126 ATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPV 3185
T G+ + R+A V ++ +D + + + P + V+A +
Sbjct: 18862 ---TAGEEYVF-RVAAVNEKG--RSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 18915
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
++ G P V+W KDG+ + R N + +L I + +D G YE+ N+
Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 18975
Query: 3246 SGAVSCHCGLVV 3257
+G+++ ++V
Sbjct: 18976 AGSITVPITIIV 18987
Score = 49.2 bits (112), Expect = 3e-04
Identities = 79/348 (22%), Positives = 131/348 (37%), Gaps = 37/348 (10%)
Query: 2915 IVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGN---NWVSLAWPKS 2971
++ E +S + +P + +P P + + N N ++L W +
Sbjct: 21619 LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP 21678
Query: 2972 DPQTTAPVLAYKVESWLIGAEGGARWVE-LGITPLNS--FDAFNLKQGEEYHFRVTPRNR 3028
+ + + Y +E + RWV+ + P++ F L +G EY F V N
Sbjct: 21679 ESDGGSEIQQYILER---REKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENA 21735
Query: 3029 YGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVK-GKPVPGVVWMKN 3087
G G +S S I + P P +K+ +T+ T S++ KPV
Sbjct: 21736 AGVGPASGISRLIKCREPVNPPG----PPTVVKVT--DTSKTTVSLEWSKPVFDGGMEII 21789
Query: 3088 GHEVEEEAGRMTS--QFNGFDCC---LTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
G+ +E + + N C T+ D+ +E ++ A N GK + V
Sbjct: 21790 GYIIEMCKTDLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDS----CEV 21845
Query: 3143 TDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWY 3202
T T+ D R E D F + V+A +RL G P P W
Sbjct: 21846 TG-TIKAVD------RLTAPELDIDANFK---QTHVVRAGASIRLFIAYQGRPTPTAVWS 21895
Query: 3203 KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
K + R + + + F TL + N +D G Y +T NNSG+ S
Sbjct: 21896 KPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKS 21941
Score = 48.8 bits (111), Expect = 3e-04
Identities = 80/323 (24%), Positives = 126/323 (39%), Gaps = 49/323 (15%)
Query: 2950 IPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT-PL 3005
+PG P V D L+W D + Y +E I G W ++
Sbjct: 9414 VPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTID---GKAWTKVNPDCGS 9470
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI--L 3063
+F +L ++Y FRV NR+G G +T I A D P + P +LKI +
Sbjct: 9471 TTFVVPDLLSEQQYFFRVRAENRFGIGPPVET---IQRTTARD-PIYPPDPPIKLKIGLI 9526
Query: 3064 AGETANLTCSVK----GKPVPGVV-----WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
T +L+ G PV + W G ++EA R ++ + + T++D+
Sbjct: 9527 TKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTG--TKKEAWRQCNKRDVEELQFTVEDL 9584
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
E + +A N G + A TV D + D PP ++
Sbjct: 9585 VEGGEYEFRVKAVNAAGVSKPSA--------TVGPCDCQ---------RPDMPPSIDLK- 9626
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYK-------DGEEVVYDKRRNKYQDEQFHTLEI 3227
V+ V + ++ G P P ++W+K + E V+YD NK + TL I
Sbjct: 9627 EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVI 9686
Query: 3228 APTNLDDGGVYEVTARNNSGAVS 3250
+ D G+Y +TA NN G S
Sbjct: 9687 PQSRRSDTGLYTITAVNNLGTAS 9709
Score = 48.8 bits (111), Expect = 3e-04
Identities = 52/191 (27%), Positives = 78/191 (40%), Gaps = 20/191 (10%)
Query: 2951 PGEPCVVDGGNNWVSLAW--PKSD--PQTTAPVLAYKVES---WLIGAEGGARWVELGIT 3003
P P V D + L W P D + T ++ YK E W G + R +L +T
Sbjct: 9927 PPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVT 9986
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLK 3061
LK+G Y FRV+ N G GE + + I + P+ +D + ++
Sbjct: 9987 --------GLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV 10038
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AG + V GKP P V W N + +EA T + + IK+ +G
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQGV 10095
Query: 3122 YSCEATNTHGK 3132
YS A N G+
Sbjct: 10096 YSLLAKNEAGE 10106
Score = 48.4 bits (110), Expect = 5e-04
Identities = 60/221 (27%), Positives = 90/221 (40%), Gaps = 38/221 (17%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EF+ P L+IL GE A CS+ + P V W K + E + +G L
Sbjct: 6056 EFIS-KPQNLEILEGEKAEFVCSISKESFP-VQW-KRDDKTLESGDKYDVIADGKKRVLV 6112
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+KD + D G Y G A A L V+ KL+
Sbjct: 6113 VKDATLQDMGTYVVMV----GAARAAAHLTVIE---------KLR--------------I 6145
Query: 3171 TMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY---QDEQFHTLEI 3227
+ L+D RV+ V C+V + K W+++ EE ++D +KY Q + +TL I
Sbjct: 6146 VVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRN-EEAIFDS--SKYIILQKDLVYTLRI 6201
Query: 3228 APTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAP 3267
+LDD Y V+ N+ G V L+V++ V P
Sbjct: 6202 RDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEP 6242
Score = 48.4 bits (110), Expect = 5e-04
Identities = 68/261 (26%), Positives = 103/261 (39%), Gaps = 37/261 (14%)
Query: 3003 TPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAG--DRPEFVDILPGQL 3060
T + D L +G+EY FRV +N++G G + + V G PE + Q
Sbjct: 8752 TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERQR 8811
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI--NIDD 3118
+ + S G P+ G + K H+ + + R+ + C T + N+D+
Sbjct: 8812 STITLDWKE-PRSNGGSPIQGYIIEKRRHD-KPDFERVNKRL-----CPTTSFLVENLDE 8864
Query: 3119 EGRYS--CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y +A N G++ L VV KL+ V GD T+
Sbjct: 8865 HQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLR----LSVRGD-----TI---- 8911
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ--------DEQFHTLEIA 3228
+V+A PV + V G P PK+ W K+ E V +K + Q E L I
Sbjct: 8912 -KVKAGEPVHIPADVTGLPMPKIEWSKN--ETVIEKPTDALQITKEEVSRSEAKTELSIP 8968
Query: 3229 PTNLDDGGVYEVTARNNSGAV 3249
+D G Y VTA N G+V
Sbjct: 8969 KAVREDKGTYTVTASNRLGSV 8989
Score = 48.4 bits (110), Expect = 5e-04
Identities = 70/304 (23%), Positives = 110/304 (36%), Gaps = 29/304 (9%)
Query: 2961 NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR-WVELGITPLN-SFDAFNLKQGEE 3018
N L W + +P+ Y +E E R W + T + L QG+
Sbjct: 10133 NESCKLTWFSPEDDGGSPITNYVIEK----RESDRRAWTPVTYTVTRQNATVQGLIQGKA 10188
Query: 3019 YHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKP 3078
Y FR+ N G G +TS ++ + PE + L ++K + T LT +
Sbjct: 10189 YFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDL--EVKEVTKNTVTLTWNPPKYD 10246
Query: 3079 VPGVV--WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
+ ++ + E + N T+K + D Y A N G+
Sbjct: 10247 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPS 10306
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRLTCQVIGSP 3195
+T K E + PP + RD+ ++ LT + G P
Sbjct: 10307 FCTKPIT----------CKDELA-------PPTLHLDFRDKLTIRVGEAFALTGRYSGKP 10349
Query: 3196 PPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL 3255
PKVSW+KD +V+ D R + LE D G Y V N++G+ C +
Sbjct: 10350 KPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQV 10409
Query: 3256 -VVD 3258
VVD
Sbjct: 10410 NVVD 10413
Score = 48.4 bits (110), Expect = 5e-04
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
++ L + G + + A V P V+W +DG L+P+ M + R+ L L +V
Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVN 12862
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
+D+G YT TA N G S + K++V+ D+ PP + + YS M +P
Sbjct: 12863 RKDSGDYTITAENSSGSKSATIKLKVL--DKPG----PPASVKINKMYSDRAMLSWEP 12914
Score = 48.0 bits (109), Expect = 6e-04
Identities = 40/143 (27%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT-VENENGAISTSANLKV 2683
V WY++G+ + KYR + L +L SD+ +YSC VE+EN + T+A L V
Sbjct: 2159 VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN--VKTTAKLIV 2216
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
E + + F + ++D LEC + + + + W+ +D ++ S+G+Y
Sbjct: 2217 ----EGAVV--EFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKY-TI 2268
Query: 2744 YLADGVCRLAIDNPTPEDSGTYT 2766
G L + + T ED G Y+
Sbjct: 2269 TSRRGRQNLTVKDVTKEDQGEYS 2291
Score = 48.0 bits (109), Expect = 6e-04
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
++ G+ +V+ KP V W NG E++E + + +G L I D + DD G
Sbjct: 25887 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGV-LTLEILDCHTDDSG 25945
Query: 3121 RYSCEATNTHGKASTYARLAV 3141
Y TN G+AS YA L V
Sbjct: 25946 TYRAVCTNYKGEASDYATLDV 25966
Score = 47.6 bits (108), Expect = 8e-04
Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A V L V G P P VSW KDG + + TLE+ N D G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 3239 EVTARNNSGAVSCHCGL-VVDK 3259
+TA N+SG+ S L V+DK
Sbjct: 12870 TITAENSSGSKSATIKLKVLDK 12891
Score = 47.6 bits (108), Expect = 8e-04
Identities = 70/325 (21%), Positives = 125/325 (38%), Gaps = 34/325 (10%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG+P + + ++ +SL W + V + VE W ++ +P++ +
Sbjct: 21263 PGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEK---KERNSILWQKVNTSPISGREY 21319
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETA 3068
A L +G +Y FRV N G S S D P D + + ET
Sbjct: 21320 RATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYID-----VTRETI 21374
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEEAGR---MTSQFNGF-DCCLTIKDINIDDEGRYSC 3124
L + P+ G+ +E+ G + F +C T+ ++ D +
Sbjct: 21375 TLKWN---PPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRI 21431
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G S ++ + + + R+ + ++ P++ L +++
Sbjct: 21432 IARNAVGTISPPSQSSGII----------MTRDENVPPIVEFGPEYFDGLI---IKSGES 21478
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF--HTLEIAPTNLDDGGVYEVTA 3242
+R+ V G P P+V+W+KDG E+ +KR N +L + D GVY V A
Sbjct: 21479 LRIKALVQGRPVPRVTWFKDGVEI--EKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEA 21536
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAP 3267
+N SG+ + V V P
Sbjct: 21537 KNASGSAKAEIKVKVQDTPGKVVGP 21561
Score = 47.6 bits (108), Expect = 8e-04
Identities = 59/243 (24%), Positives = 103/243 (42%), Gaps = 27/243 (11%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
L +G ++FRV P N YG GE +TS ++ L + P ++P +L+++ + +T
Sbjct: 23104 LVEGTMHYFRVLPENIYGIGEPCETSDAV---LVSEVP----LVPAKLEVVDVTKSTVTL 23156
Query: 3073 SVKGKPVPGVVWMKNGHEVEE-EAG--RMTSQFNGFDCCL--TIKDINIDDEGRYSCEAT 3127
+ + KP+ G+ +E +AG R L T+ +N ++ + A
Sbjct: 23157 AWE-KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQ 23215
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G + + VT + D ++ ++ PQ T+ V A PV L
Sbjct: 23216 NEKGVSEPRETVTAVTVQ-----DLRVL----PTIDLSTMPQKTIH-----VPAGRPVEL 23261
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
+ G PPP SW+ G ++ +R + L I T + D G Y + +N +G
Sbjct: 23262 VIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 23321
Query: 3248 AVS 3250
S
Sbjct: 23322 TTS 23324
Score = 47.2 bits (107), Expect = 0.001
Identities = 79/330 (23%), Positives = 122/330 (36%), Gaps = 52/330 (15%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++ +S + + EF+ L L++ E A C + + V W K+G E++
Sbjct: 5860 DAKDFKTSCNLNVVPPHVEFLRPLT-DLQVREKEMARFECELSRENAK-VKWFKDGAEIK 5917
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
+ + G L I +DDE YSCE A T L V+ + V
Sbjct: 5918 K-GKKYDIISKGAVRILVINKCLLDDEAEYSCEVRT----ARTSGMLTVLEEEAV----- 5967
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
FT L + V T ++L C+V P +V WYK EE++
Sbjct: 5968 -----------------FTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETG 6009
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
R + + L I +L+D G Y + + G V H +A EF
Sbjct: 6010 RYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-----------ELAAEFI 6058
Query: 3271 CGLEPLYKLH-EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
+ L L E E S E++P V W RD L + + D ++ L +
Sbjct: 6059 SKPQNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVK 6114
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
T +D G Y VG A + + VI
Sbjct: 6115 DATLQDMGTYVVM----VGAARAAAHLTVI 6140
Score = 47.2 bits (107), Expect = 0.001
Identities = 65/247 (26%), Positives = 96/247 (38%), Gaps = 30/247 (12%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI--LA 3064
SF NL G EY+FRVT N YG G + + LA D D P +L+ +
Sbjct: 12259 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPV---LASDPLSEPDP-PRKLEATEMT 12314
Query: 3065 GETANLTCSVK----GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+A L G + G ++ + E E+ A R T D L + + +
Sbjct: 12315 KNSATLAWLPPLRDGGAKIDG--YIISYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKY 12372
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
++ A N G + R A V+EA +L PP+ M ++
Sbjct: 12373 KFRVAARNAVGVS--LPREA----EGVYEAKEQL-----------LPPKILMP-EQITIK 12414
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
A +R+ V G P P W K +EVV ++ + L I D G Y +
Sbjct: 12415 AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSL 12474
Query: 3241 TARNNSG 3247
TA N+SG
Sbjct: 12475 TAENSSG 12481
Score = 47.2 bits (107), Expect = 0.001
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 3/112 (2%)
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
E+ ENE G + S P + ++D L C+I G+PL
Sbjct: 24005 EFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 24064
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSV 2773
P I W++ K++ +Y+ +DG L + ED G YTC A N V
Sbjct: 24065 PDIKWYRFGKELIQSRKYK--MSSDGRTHTLTVMTEEQEDEGVYTCIATNEV 24114
Score = 47.2 bits (107), Expect = 0.001
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 4/116 (3%)
Query: 2660 DSAEYSCTVENEN-GAISTSANLK--VYPSFEASPIPPTFTRSIRDTFHLAENELVLECR 2716
+ EY V+ EN G S + + + P + P F +R+ ++ L C+
Sbjct: 24394 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 24453
Query: 2717 IRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ G P P + W++ K+I +DG +Y+ G +L I + T +D+ Y +A N
Sbjct: 24454 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATN 24509
Score = 46.8 bits (106), Expect = 0.001
Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 18/162 (11%)
Query: 3198 KVSWYKDGEEVVYDKRRNKYQDE-QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
+V W+K+ + + + R QDE + H++ ++DD V A +S L
Sbjct: 5461 RVKWFKNDQRL-HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMG----MSSEAKLT 5515
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIM 3316
V +G P F L+ Y E DE+ + + V W++DG ++PS+ A++
Sbjct: 5516 VLEG-----DPYFTGKLQD-YTGVEKDEVILQCEISK-ADAPVKWFKDGKEIKPSKNAVI 5568
Query: 3317 TLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
D ++ L L D G YTC + G TSGK+++
Sbjct: 5569 KTDGKKRM-LILKKALKSDIGQYTC----DCGTDKTSGKLDI 5605
Score = 46.8 bits (106), Expect = 0.001
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG+P V D G V L W K + A + +Y +E G + R E G+ P
Sbjct: 7490 PGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAE-GV-PTTQHLL 7547
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
L +G+EY FRV N+ G E S+ S +
Sbjct: 7548 PGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 7578
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P T L D EG + C V S +D V+WY + +R + LE+
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A P D Y+ N G +S++ANL +
Sbjct: 3358 AEAYPEDEGTYTFVANNAVGQVSSTANLSL 3387
Score = 46.4 bits (105), Expect = 0.002
Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 6/142 (4%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L++ G A TC ++ P W K G E+ E+ + + + + + L I + D
Sbjct: 4346 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCSIRSSKYISSLEILRTQVVDC 4404
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---- 3175
G Y+C+A+N +G S A L V + KL ER E + + + +R R
Sbjct: 4405 GEYTCKASNEYGSVSCTATLTVTVPGGEKKV-RKLLPERKPEPKEEVVLKSVLRKRPEEE 4463
Query: 3176 DRRVQATYPVRLTCQVIGSPPP 3197
+ +V+ ++ + PPP
Sbjct: 4464 EPKVEPKKLEKVKKPAVPEPPP 4485
Score = 46.4 bits (105), Expect = 0.002
Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 18/199 (9%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGI 3002
P PER+ + + ++L W + +P+ Y +E R V +
Sbjct: 8797 PPTSPERLT----YTERQRSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFER-VNKRL 8851
Query: 3003 TPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF---VDILP 3057
P SF NL + + Y FRV N G S+ S + V + D P + +
Sbjct: 8852 CPTTSFLVENLDEHQMYEFRVKAVNEIG---ESEPSLPLNVVIQDDEVPPTIKLRLSVRG 8908
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQ---FNGFDCCLTIK 3112
+K+ AGE ++ V G P+P + W KN +E+ +A ++T + + L+I
Sbjct: 8909 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 8968
Query: 3113 DINIDDEGRYSCEATNTHG 3131
+D+G Y+ A+N G
Sbjct: 8969 KAVREDKGTYTVTASNRLG 8987
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G R V++ P+ V WY +GV L+ S + T + G + L + T D+G Y
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRA 25949
Query: 3342 TASNEVGRASTSGKVEVIGTDQTS 3365
+N G AS ++V G D T+
Sbjct: 25950 VCTNYKGEASDYATLDVTGGDYTT 25973
Score = 46.0 bits (104), Expect = 0.002
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
Y + G +L++ + P +TW +DG+ L+ + R +T D L++ D
Sbjct: 16742 YSVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLDLTTLSIKETHKDDG 16800
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
G Y T +N VG+ + S +E++ D+ P+ P
Sbjct: 16801 GQYGITVANVVGQKTAS--IEIVTLDKPDPPKGP 16832
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 18/140 (12%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS----- 3353
VTWY+DG +L+ + DG EL + +T D G Y C S E G + T+
Sbjct: 26252 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 26311
Query: 3354 -------GKVEVIGTDQTSEPRIPPVVISPDV------PYSKEPMFIRKPRSSEAREGDT 3400
KV I + S+ + ++ P S +P+ + + +
Sbjct: 26312 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSV 26371
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
+ G+P+P W +D
Sbjct: 26372 AKFAVKATGEPRPTAIWTKD 26391
Score = 46.0 bits (104), Expect = 0.002
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 6/162 (3%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V W +G E+ + TL I + D G+ ++ G V C L +
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 26630
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
K + AP F ++EG + + + PS + W+++ + + S ++
Sbjct: 26631 KELSD--APAFISQPRS-QNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 26687
Query: 3319 DRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
R+ +E+ A+V+ D+G YT A N G+ S + + V+
Sbjct: 26688 SRNVYSLEIRNASVS--DSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 8/137 (5%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
+++ PS EA P F R T ++ R+ G+P P+ W+K+ +I R
Sbjct: 2023 IELSPSMEA---PKIFERIQSQTVGQG-SDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVV 2796
++ D VC L I + T EDS + KA N F+ ++ +Q +VV
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVV 2138
Query: 2797 TAEKTRIARQSLESRRP 2813
EK +A E+ P
Sbjct: 2139 AKEKDTMATFECETSEP 2155
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD LR+SA+++ P VTW ++ R P++ I ++E+ AA D G+Y+
Sbjct: 10736 GDTLRLSAIIKGVPFPKVTWKKED-RDAPTKARIDVTPVGSKLEIRNAA--HEDGGIYSL 10792
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPR 3368
T N G + S KV V+ D+ PR
Sbjct: 10793 TVENPAGSKTVSVKVLVL--DKPGPPR 10817
Score = 45.6 bits (103), Expect = 0.003
Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 23/254 (9%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
S+ L++G Y+FRV N YG G ++T+ S+ A +RP + PG++ ++
Sbjct: 15512 SWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVK---ASERP----LPPGKITLMDVT 15564
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
+++ S + KP G+ VE + T + + C T+K G
Sbjct: 15565 RNSVSLSWE-KPEHDGGSRILGYIVEMQ----TKGSDKWATCATVKVTEATITGLIQ--- 15616
Query: 3127 TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVR 3186
G+ ++ R++ ++ + +D + + PP F + V A ++
Sbjct: 15617 ----GEEYSF-RVSAQNEKGI--SDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 15669
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
+ IG P P V+W+KD + R N E L I +D G Y V N++
Sbjct: 15670 VDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSA 15729
Query: 3247 G-AVSCHCGLVVDK 3259
G A+ +V+DK
Sbjct: 15730 GEAIETLNVIVLDK 15743
Score = 45.2 bits (102), Expect = 0.004
Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 5/108 (4%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLD 2635
S ISE ++++ KP D +EG ++ + + PTV+W+++G V
Sbjct: 7875 SEISEN-VVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS 7933
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
++L + + LEV +V +D+ Y+ T+EN+ G+ + S N+KV
Sbjct: 7934 DRLTMKNDHISA--HLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 45.2 bits (102), Expect = 0.004
Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 8/160 (5%)
Query: 2652 EVLNAVPSDSAEYSCTVENENGAIS--TSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
EV V E+ N G S + + + E P + +DT +
Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAG 16061
Query: 2710 E-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
E ++ I G+P+P I W K D+++ + R + D L++ + DSG Y K
Sbjct: 16062 ESFKVDADIYGKPIPTIQWIKGDQELSNTARLE-IKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 2769 AENSVWTDQITHFVNFTGR----ESQVSPNVVTAEKTRIA 2804
A+N +T V R E V + VTAEK +A
Sbjct: 16121 AKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLA 16160
Score = 45.2 bits (102), Expect = 0.004
Identities = 76/309 (24%), Positives = 119/309 (38%), Gaps = 34/309 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P V + + + W + ++ Y +E + WV+L TP+ F
Sbjct: 18011 PGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ---KEKNSILWVKLNKTPIQDTKF 18067
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETA 3068
L +G EY F+V+ N G G+ S+ S +A D + PG+ + +
Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF---VARDPCD----PPGRPEAIVITRN 18120
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEE---AGR-MTSQF-NGFDCCLTIKDINIDDEGRYS 3123
N+T K KP G+ VE++ GR M + F N + T+ + D +
Sbjct: 18121 NVTLKWK-KPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFR 18179
Query: 3124 CEATNTHGKASTYA-RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
A N G S + +T R E DA +A ++ Y + + V
Sbjct: 18180 VIARNAAGNFSEPSDSSGAITARD--EIDAP-----NASLDPKYKDVIVVHAGETFV--- 18229
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE-QFHTLEIAPTNLDDGGVYEVT 3241
L + G P P V W KDG+E+ R + + Q TL + DGG Y +
Sbjct: 18230 ----LEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILK 18285
Query: 3242 ARNNSGAVS 3250
N G S
Sbjct: 18286 LSNVGGTKS 18294
Score = 45.2 bits (102), Expect = 0.004
Identities = 25/76 (32%), Positives = 31/76 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G + +V S V WY NGV L K G++TLE+L+ DS Y
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 25950
Query: 2668 VENENGAISTSANLKV 2683
N G S A L V
Sbjct: 25951 CTNYKGEASDYATLDV 25966
Score = 44.8 bits (101), Expect = 0.006
Identities = 49/167 (29%), Positives = 74/167 (44%), Gaps = 19/167 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGL-ITLE 2652
P F+ L D+TAVE + L C V S D V W+++G + KY K DGL L+
Sbjct: 5166 PYFTVKLHDKTAVEKDEITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIK-ADGLRRILK 5222
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFH----LA 2707
+ A D EY C + G T AN+ V P + +T H L+
Sbjct: 5223 IKKADLKDKGEYVC----DCGTDKTKANVTVEARLIEVEKPLYGVEVFVGETAHFEIELS 5278
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
E ++ + +++GQPL D +I DG+ L + C+L +
Sbjct: 5279 EPDVHGQWKLKGQPLTA----SPDCEIIEDGKKHILILHN--CQLGM 5319
Score = 44.8 bits (101), Expect = 0.006
Identities = 77/309 (24%), Positives = 123/309 (39%), Gaps = 35/309 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P + + + W + +PV+ Y +E W ++ T ++ F
Sbjct: 16929 PGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER---KERNSILWTKVNKTIIHDTQF 16985
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE-T 3067
A NL++G EY FRV N G G++S+ S D P P + + E T
Sbjct: 16986 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG----TPEPIMVKRNEIT 17041
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEE---AGR-MTSQF-NGFDCCLTIKDINIDDEGRY 3122
T KPV M G+ VE+ GR M + F N + T+ + D +
Sbjct: 17042 LQWT-----KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEF 17096
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
A N G S + + T + + +L R + D P+F + V A
Sbjct: 17097 RVIAKNAAGAIS---KPSDSTGPITAKDEVELPR-----ISMD--PKFRDTI---VVNAG 17143
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD-DGGVYEVT 3241
RL V G P P + W + G++ + + R + ++ F L I + DGG Y +
Sbjct: 17144 ETFRLEADVHGKPLPTIEWLR-GDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILR 17202
Query: 3242 ARNNSGAVS 3250
A N +G+ S
Sbjct: 17203 ASNVAGSKS 17211
Score = 44.4 bits (100), Expect = 0.007
Identities = 38/155 (24%), Positives = 62/155 (40%), Gaps = 24/155 (15%)
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTA 3343
E R++ + + P++ V W DG L + R M ++ G L +RD+G+ TC A
Sbjct: 1677 ECRLTPISD--PTMVVEWLHDGKPLEAANRLRM-INEFGYCSLDYGVAYSRDSGIITCRA 1733
Query: 3344 SNEVGRASTSGKVEVIGTDQ-TSEPRIPP--------------------VVISPDVPYSK 3382
+N+ G TS + V E ++P ++ D +
Sbjct: 1734 TNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQ 1793
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+P + P EG+T C V G P+P V W
Sbjct: 1794 KPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNW 1828
Score = 44.4 bits (100), Expect = 0.007
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 12/137 (8%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELV-LECRI 2717
+ EY V+ N A + + V P P +PP+ +++ + E V + +I
Sbjct: 9586 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSI--DLKEFMEVEEGTNVNIVAKI 9643
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFY-------LADGVCRLAIDNPTPEDSGTYTCKAE 2770
+G P P +TWFK + P D + Y + D C L I D+G YT A
Sbjct: 9644 KGVPFPTLTWFKAPPKKP-DNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAV 9702
Query: 2771 NSVWTDQITHFVNFTGR 2787
N++ T +N GR
Sbjct: 9703 NNLGTASKEMRLNVLGR 9719
Score = 44.4 bits (100), Expect = 0.007
Identities = 42/140 (30%), Positives = 66/140 (47%), Gaps = 15/140 (10%)
Query: 3230 TNLDDGGVYE--VTARNNSGAVSC---HCGLVVDKGIRAYVAPEFCCGLEPLYK----LH 3280
T+L +GG YE + A+N +GA+S ++ K Y AP L+P K +
Sbjct: 13839 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKD--EYEAPTIV--LDPTIKDGLTIK 13894
Query: 3281 EGDELRISAV-VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
GD + ++A+ + P +W + G +RPS +T + L + T +DAG Y
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM-LTIKYATRKDAGEY 13953
Query: 3340 TCTASNEVGRASTSGKVEVI 3359
T TA+N G KV V+
Sbjct: 13954 TITATNPFGTKVEHVKVTVL 13973
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+P+ V + P +++L GETA C V G P P V W NG ++ ++ R +++G
Sbjct: 1794 KPDIV-LYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIH-Y 1850
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I D D G A N G +L +
Sbjct: 1851 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 44.0 bits (99), Expect = 0.010
Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 16/212 (7%)
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +K VEG +F L+D V +Y L C ++ + WY + E+
Sbjct: 2205 DENVKTTAKLIVEGAVV-EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKS 2262
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+ + L + +D G Y C L + A +
Sbjct: 2263 NGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT----CKLKMKPRPIAILQ---- 2314
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL K+ EGD +++ V GV W +DG ++PS R + +D+ + L +
Sbjct: 2315 -GLSD-QKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHM-LLIED 2370
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+T DAG Y+ T +G STSG+V V D
Sbjct: 2371 MTKEDAGNYSFTIP-ALG-LSTSGRVSVYSVD 2400
Score = 44.0 bits (99), Expect = 0.010
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 7/118 (5%)
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L L I+G P PK+TW K+D+ P+ R + +L I N ED G Y+ E
Sbjct: 10739 LRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS---KLEIRNAAHEDGGIYSLTVE 10795
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP--HFGNVLTDYQVAR 2826
N + ++ V + P + + R L + P G+V+T+Y V R
Sbjct: 10796 NPAGSKTVS--VKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVER 10851
Score = 44.0 bits (99), Expect = 0.010
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 2/120 (1%)
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + + + + +NE G IS L V + IPP F LA +L
Sbjct: 15611 ITGLIQGEEYSFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 15669
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
++ G+P P +TW KD+ + R A + L I + ED G Y K NS
Sbjct: 15670 VDVPFIGRPTPAVTWHKDNVPLKQTTRVNA-ESTENNSLLTIKDACREDVGHYVVKLTNS 15728
Score = 44.0 bits (99), Expect = 0.010
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+G+P P +TW KD+K + SD RY + D L I T D+G Y EN V
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARY-SIENTDSSSLLTIPQVTRNDTGKYILTIENGV 20853
Score = 43.6 bits (98), Expect = 0.013
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPNPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
Score = 43.6 bits (98), Expect = 0.013
Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 2/107 (1%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
++ S K T+ + + PV + G K TC + S+ + W++ G +
Sbjct: 4322 KTATSAKLTVVKRAA--PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE 4379
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
K + + +LE+L D EY+C NE G++S +A L V
Sbjct: 4380 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 43.2 bits (97), Expect = 0.017
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L+D+ EG V+L V S V W ++G + + + L + +
Sbjct: 2316 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKE 2374
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ YS T+ +STS + VY +P+ +D + + VLEC++
Sbjct: 2375 DAGNYSFTIPALG--LSTSGRVSVYSVDVITPL--------KDVNVIEGTKAVLECKVSV 2424
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ + W+ +D+QI D R QA + RL I+ D G Y
Sbjct: 2425 PDVTSVKWYLNDEQIKPDDRVQAI-VKGTKQRLVINRTHASDEGPY 2469
Score = 43.2 bits (97), Expect = 0.017
Identities = 30/118 (25%), Positives = 51/118 (43%), Gaps = 4/118 (3%)
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT--FTRSIRDTFHLAENE-LVLE 2714
P D E+ N G IS + +PP F D + E L ++
Sbjct: 21423 PGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIK 21482
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
++G+P+P++TWFKD +I + + G L + + T + G YT +A+N+
Sbjct: 21483 ALVQGRPVPRVTWFKDGVEIEKRMNMEITNVL-GSTSLFVRDATRDHRGVYTVEAKNA 21539
Score = 43.2 bits (97), Expect = 0.017
Identities = 56/205 (27%), Positives = 86/205 (41%), Gaps = 15/205 (7%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---D 2702
D T+ L+ D+ E+ +N G IS + + PP R D
Sbjct: 22501 DNFFTVTALSE--GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 22558
Query: 2703 TFHL-AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ A ++LVL+ + G+P PKI W K DK++ + Y + I D
Sbjct: 22559 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSD 22617
Query: 2762 SGTYTCKAENSVWTDQITHFV---NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
SG YT +N+ T ++ V + G +++ + VT EK +A SL + G
Sbjct: 22618 SGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLA-WSLP--QEDGGAE 22674
Query: 2819 LTDYQVARGGTIGLQ-VEIRG-CPT 2841
+T Y V R T L V + G CPT
Sbjct: 22675 ITHYIVERRETSRLNWVIVEGECPT 22699
Score = 42.7 bits (96), Expect = 0.022
Identities = 58/243 (23%), Positives = 93/243 (38%), Gaps = 36/243 (14%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+D ++DD+ Y+ TN G+ A +V E D ++ E ++E
Sbjct: 6199 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVE-----EEDLRIV-EPLKDIETMEKK 6252
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
T + R+ T + W K+GEEV +D R + D+ H L I
Sbjct: 6253 SVTFWCKVNRLNVT----------------LKWTKNGEEVPFDNRVSYRVDKYKHMLTIK 6296
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
D G Y VTA + L+++ EF LE + E D+ S
Sbjct: 6297 DCGFPDEGEYIVTAGQDKSVAEL---LIIE------APTEFVEHLED-QTVTEFDDAVFS 6346
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASNEV 3347
+ + V WYR+G ++ ++ ++DG I L + D Y C +
Sbjct: 6347 CQL-SREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDECEYACGVEDRK 6403
Query: 3348 GRA 3350
RA
Sbjct: 6404 SRA 6406
Score = 42.7 bits (96), Expect = 0.022
Identities = 42/156 (26%), Positives = 59/156 (37%), Gaps = 3/156 (1%)
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
DN ++ KLV L T +V + Y + EN+ G S L + +A P
Sbjct: 6839 DNWIRCNMKLVPEL-TYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPT 6897
Query: 2695 TFTRSIRDTFH-LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ +D + N + + G P P TW DK + + R + L+ L
Sbjct: 6898 MDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS-AYAELV 6956
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
I D G YT K EN V T VN R S
Sbjct: 6957 ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPS 6992
Score = 42.7 bits (96), Expect = 0.022
Identities = 21/63 (33%), Positives = 30/63 (47%)
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
P P VSW+KDG+EV R D LE+ + D G+Y +T N G+ +
Sbjct: 7917 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 7976
Query: 3255 LVV 3257
+ V
Sbjct: 7977 VKV 7979
Score = 42.7 bits (96), Expect = 0.022
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASP--IPPTFTRSIRDTFHLAENELVLECRI 2717
+ +Y V N A+ S + +EA +PP + T A +L +E +
Sbjct: 12368 EGKKYKFRVAARN-AVGVSLPREAEGVYEAKEQLLPPKILMPEQITIK-AGKKLRIEAHV 12425
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G+P P W K + ++ + + A + AD L I + T +DSG Y+ AENS TD
Sbjct: 12426 YGKPHPTCKWKKGEDEVVTSS-HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTD 12483
Score = 42.7 bits (96), Expect = 0.022
Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLY-TL 2870
PHF L + V L ++ G P V+W R+G+ + R+ +G Y L
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
++ VT+ ++ +Y RA + G+V A++ V P+ + P + G L GE
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGMGAVHAL--RGEV 24547
Query: 2931 INISFRTQGEPKP 2943
++I G+P P
Sbjct: 24548 VSIKIPFSGKPDP 24560
Score = 42.7 bits (96), Expect = 0.022
Identities = 47/233 (20%), Positives = 85/233 (36%), Gaps = 10/233 (4%)
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA-EVEGDYPPQFTMRLRDRRVQATY 3183
+ T T S+Y A ++ + L+ + + +++ + + R V
Sbjct: 26020 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGE 26079
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
R +C G P P V+W + G+ + R + T EI+ D G Y V
Sbjct: 26080 SARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 26139
Query: 3244 NNSGAVSCHCGLVVDKG---IRAYVAPEFCCGLEPLYKLHEG--DELRISAVVEAYP-SV 3297
N+ G L + K +A +P EP K E R+ + ++P +V
Sbjct: 26140 NSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAV 26199
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
T + R + + + +I L A +++ TC + V RA
Sbjct: 26200 SPTETKPTPREKVQH---LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRA 26249
Score = 42.3 bits (95), Expect = 0.030
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 2685 PSFEASPI-------PPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPS 2736
PSF PI PPT RD + E L R G+P PK++WFKD+ +
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364
Query: 2737 DGRYQAFYLADGVCRLAID--NPTPEDSGTYTCKAENS 2772
D R ++ LA++ DSG Y ENS
Sbjct: 10365 DDR---THIKTTPATLALEKIKAKRSDSGKYCVVVENS 10399
Score = 42.3 bits (95), Expect = 0.030
Identities = 57/243 (23%), Positives = 91/243 (37%), Gaps = 26/243 (10%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
SF NL++G+ Y FRV N YG G+ +T ++ A P V LK+ +
Sbjct: 13347 SFRVPNLEEGKSYFFRVFAENEYGIGDPGETRDAVK---ASQTPGPVV----DLKVRSVS 13399
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
++ + K KP G+ V+ E + + KD+ E +
Sbjct: 13400 KSSCSIGWK-KPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRV 13458
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N +G+ T + + VV V D LK P + + + P
Sbjct: 13459 SAENENGEG-TPSEITVVARDDVVAPDLDLK---------GLPDLCYLAKENSNFRLKIP 13508
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
++ G P P VSW K + + D R + TL + D G Y +T +N
Sbjct: 13509 IK------GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13562
Query: 3245 NSG 3247
+G
Sbjct: 13563 VAG 13565
Score = 41.9 bits (94), Expect = 0.039
Identities = 40/171 (23%), Positives = 70/171 (40%), Gaps = 15/171 (8%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN 2655
F L D+T E +C +S V WYRNG + KY+ + + L + +
Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQ-LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6386
Query: 2656 AVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLEC 2715
D EY+C VE+ + A L V IP R +D ++V
Sbjct: 6387 CRLDDECEYACGVEDR----KSRARLFV------EEIPVEIIRPPQDILEAPGADVVFLA 6436
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTY 2765
+ + ++ W +++ + ++Q +++G + RL I + P D G Y
Sbjct: 6437 ELNKDKV-EVQWLRNNMVVVQGDKHQ--MMSEGKIHRLQICDIKPRDQGEY 6484
Score = 41.9 bits (94), Expect = 0.039
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 2689 ASPIPPTFTRSIRDTFHL---AENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFY 2744
A +PP S+ L A + L+ + G+P+P ++W KD + P++G A
Sbjct: 12791 AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMA-- 12848
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ +C L + + +DSG YT AENS
Sbjct: 12849 MQRNLCTLELFSVNRKDSGDYTITAENS 12876
Score = 41.9 bits (94), Expect = 0.039
Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 2612 KLTCSVISS--SDPTVTWYRNGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTV 2668
KLTC V SS VTWY++G L ++ DG L++ N SD EY C +
Sbjct: 26237 KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI 26296
Query: 2669 ENENGAISTS 2678
E G T+
Sbjct: 26297 SGEGGTSKTN 26306
Score = 41.5 bits (93), Expect = 0.052
Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P F ++ G +++ G P W +G+ + Y + V E G +L
Sbjct: 1410 KPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
+ T ++SG +T A + G ++ +T V+ + KP + K++ I G
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFV--EKLKNVNIKEGSR 1526
Query: 2931 INISFRTQGEPKPKAV 2946
+ + R G P P V
Sbjct: 1527 LEMKVRATGNPNPDIV 1542
Score = 41.5 bits (93), Expect = 0.052
Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 6/76 (7%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCR- 2751
P FT ++D + ++E++L+C I P + WFKD K+I PS A DG R
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSK---NAVIKTDGKKRM 5576
Query: 2752 LAIDNPTPEDSGTYTC 2767
L + D G YTC
Sbjct: 5577 LILKKALKSDIGQYTC 5592
Score = 41.5 bits (93), Expect = 0.052
Identities = 45/171 (26%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR--SIR-DTFHLAENELV-LECRIR 2718
E+ NE G S L V + +PPT S+R DT + E V + +
Sbjct: 8869 EFRVKAVNEIGESEPSLPLNVV--IQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVT 8926
Query: 2719 GQPLPKITWFKDDKQI--PSDG---RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
G P+PKI W K++ I P+D + ++ L+I ED GTYT A N +
Sbjct: 8927 GLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 8986
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
+ V R S VT K + ++ + G+ +T Y +
Sbjct: 8987 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9037
Score = 41.5 bits (93), Expect = 0.052
Identities = 74/314 (23%), Positives = 119/314 (37%), Gaps = 23/314 (7%)
Query: 2940 EPKPKAVPERIPGE---PCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR 2996
EP P PG P + + + ++++W +P+ Y +E A
Sbjct: 12980 EPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQA---VN 13036
Query: 2997 WVELGITPL--NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVD 3054
W ++ P+ + A L++G EY FRVT N+ G G+ S S + A D P++
Sbjct: 13037 WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKA---AYARD-PQYPP 13092
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
P K+ ++++ S GKP G+ VE + R S N C L
Sbjct: 13093 APPAFPKVYDTTRSSVSLS-WGKPAYDGGSPIIGYLVEVK--RADSD-NWVRCNLPQNLQ 13148
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
E E T + ++ V D ++ EG++ L
Sbjct: 13149 KTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDV--PDKHYPKDILIPPEGEHDADLRKTL 13206
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLD 3233
++A +RL V G PPPK++W K + D+ + F T L N
Sbjct: 13207 ---ILRAGVTMRLYVPVKGRPPPKITWSKPNVN-LRDRIGLDIKSTDFDTFLRCENVNKY 13262
Query: 3234 DGGVYEVTARNNSG 3247
D G Y +T N+ G
Sbjct: 13263 DAGKYILTLENSCG 13276
Score = 41.5 bits (93), Expect = 0.052
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 2961 NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS-FDAFNLKQGEEY 3019
+++V+ +W + P+ Y VE + WVEL T + + + A L G EY
Sbjct: 14676 SDFVTFSWDPPENDGGVPISNYVVE---MRQTDSTTWVELATTVIRTTYKATRLTTGLEY 14732
Query: 3020 HFRVTPRNRYGWG 3032
FRV +NRYG G
Sbjct: 14733 QFRVKAQNRYGVG 14745
Score = 41.1 bits (92), Expect = 0.068
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 26/254 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL EY+FRV N+ G G + +T + I DRP GE NL
Sbjct: 11566 NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRP--------------GEPENLH 11611
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEE--AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
+ KGK + W + ++ + + + G D + +I E Y +
Sbjct: 11612 IADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK-ETHYMVDRCVE 11670
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD-RRVQATYPVRLT 3188
+ Y V T E+D +K E E P ++L V+A +RL
Sbjct: 11671 N---QIY-EFRVQTKNEGGESDW-VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLE 11725
Query: 3189 CQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL--DDGGVYEVTARNNS 3246
V G P P+V+W KD + + D + + + + T DGG Y VTA N +
Sbjct: 11726 AGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTA 11785
Query: 3247 GAVSCHCGL-VVDK 3259
G+ + + V+DK
Sbjct: 11786 GSFVAYATVNVLDK 11799
Score = 41.1 bits (92), Expect = 0.068
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P V + + + W + + V+ Y +E WV+L TP+ F
Sbjct: 15847 PGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLER---KERNSILWVKLNKTPIPQTKF 15903
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTS 3038
L++G EY FRV+ N G G+ S+ S
Sbjct: 15904 KTTGLEEGVEYEFRVSAENIVGIGKPSKVS 15933
Score = 40.7 bits (91), Expect = 0.090
Identities = 25/91 (27%), Positives = 37/91 (40%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP L++ V V L C + G P P V+WY++ ++ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G + +A N +G VS C L V
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 40.7 bits (91), Expect = 0.090
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTI 3111
FV L ++ ++ G+ L+C + + VVW K+G V E+ GR+ G LTI
Sbjct: 4717 FVKTLEEEVTVVKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGRIVPGVIGLMRALTI 4774
Query: 3112 KDINIDDEGRYSCEATNTH 3130
D + D G Y+ N +
Sbjct: 4775 NDADDTDAGTYTVTVENAN 4793
Score = 40.7 bits (91), Expect = 0.090
Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 4/102 (3%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A VLE IRG+P+P + W KD K++ L + + D G Y
Sbjct: 18224 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 2767 CKAENSVWTDQITHFVNFTGR----ESQVSPNVVTAEKTRIA 2804
K N T I V R E + VTAEK +A
Sbjct: 18284 LKLSNVGGTKSIPITVKVLDRPGSPEGPLKVTGVTAEKCYLA 18325
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G L++ + P VT RDGV L+ + R + + + + L T DAG Y
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAEN-LTINLKESVTADAGRYEI 20052
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVIS 3375
TA+N G +T + ++ D+ P PVVIS
Sbjct: 20053 TAANSSG--TTKAFINIVVLDRPGPP-TGPVVIS 20083
Score = 40.3 bits (90), Expect = 0.12
Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 15/173 (8%)
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
L+D V A C++ P V WY G+++ + + + HTL + L+
Sbjct: 5705 LKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 5763
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA 3293
D G ++TA++ H L V + EF LE + EG + V +
Sbjct: 5764 DAGEVQLTAKD----FKTHANLFVKE-----PPVEFTKPLED-QTVEEGATAVLECEV-S 5812
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASN 3345
+ V W+++G + S++ + DG++ +L + T D YTC A +
Sbjct: 5813 RENAKVKWFKNGTEILKSKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 40.3 bits (90), Expect = 0.12
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 3167 PPQFTMRLRDRR---VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ + R+ V+A P+RL V G P PKV+W K G + V K + D
Sbjct: 12106 PPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF 12165
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSG 3247
L I + DD G Y +T N +G
Sbjct: 12166 -LVIPNSTRDDSGKYSLTLVNPAG 12188
Score = 39.9 bits (89), Expect = 0.16
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 17/169 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E +L C ++S + WY N V L + KY G L V +
Sbjct: 2227 LQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKE 2285
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIR 2718
D EYS ++ + T+ LK+ P P + + D + E ++V LE ++
Sbjct: 2286 DQGEYSFVIDGK----KTTCKLKM------KPRPIAILQGLSDQ-KVCEGDIVQLEVKVS 2334
Query: 2719 GQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
+ + + W KD +++ PSD + + L I++ T ED+G Y+
Sbjct: 2335 LESVEGV-WMKDGQEVQPSDRVH--IVIDKQSHMLLIEDMTKEDAGNYS 2380
Score = 39.9 bits (89), Expect = 0.16
Identities = 46/185 (24%), Positives = 76/185 (41%), Gaps = 20/185 (10%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLN 2655
T L D +EG++ L C V +V WY N + D+++ + +V G V+N
Sbjct: 2403 TPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVIN 2459
Query: 2656 AV-PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
SD Y V G + T+ NL V E I R +RD +V E
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSV----EKIKI----IRGLRDLTCTETQNVVFE 2507
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
+ + + W DK+I +Y+ + +L + N +D G YT A ++
Sbjct: 2508 VELSHSGI-DVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEGKYTFYAGENMT 2565
Query: 2775 TDQIT 2779
+ ++T
Sbjct: 2566 SGKLT 2570
Score = 39.9 bits (89), Expect = 0.16
Identities = 45/187 (24%), Positives = 74/187 (39%), Gaps = 21/187 (11%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L + T E T + + V W +NGV+L++ KY + + +L + N
Sbjct: 2667 LKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIV 2726
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D + Y + G + SA L V E I + +D L + E +
Sbjct: 2727 DESVYGFRL----GRLGASARLHV----ETVKI----IKKPKDVTALENATVAFEVSVSH 2774
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT-------CKAENS 2772
+P + WF +I +++ V +L + N +P D+G YT CKA+
Sbjct: 2775 DTVP-VKWFHKSVEIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLF 2832
Query: 2773 VWTDQIT 2779
V T IT
Sbjct: 2833 VETLHIT 2839
Score = 39.9 bits (89), Expect = 0.16
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 11/169 (6%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN-NSGAVSCHCGLVV 3257
++W G + ++ NK E+ L+ +L +GG YE + N+ VS V
Sbjct: 9554 LAWDPTGTKKEAWRQCNKRDVEE---LQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVG 9610
Query: 3258 DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIM- 3316
+ P L+ ++ EG + I A ++ P +TW++ + ++ ++
Sbjct: 9611 PCDCQRPDMPP-SIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY 9669
Query: 3317 -----TLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
L D L + D G+YT TA N +G AS ++ V+G
Sbjct: 9670 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9718
Score = 39.9 bits (89), Expect = 0.16
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +RI A V+ P +TW ++G L +R + D ++EL + D G Y
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLP-RVELQIKEAVRADHGKYII 11484
Query: 3342 TASNEVGRASTSGKVEVI 3359
+A N G A S V V+
Sbjct: 11485 SAKNSSGHAQGSAIVNVL 11502
Score = 39.9 bits (89), Expect = 0.16
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 2701 RDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+DT L E LE + G+P P + W KD K++ + + +AD L + T
Sbjct: 14971 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE-IKIADFSTNLVNKDSTR 15029
Query: 2760 EDSGTYTCKAEN 2771
DSG YT A N
Sbjct: 15030 RDSGAYTLTATN 15041
Score = 39.9 bits (89), Expect = 0.16
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
L G+ R+ A V P + W +DG L + + + + D L T RD+G
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGA 15034
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVV 3373
YT TA+N G A V+V+ D+ P P V
Sbjct: 15035 YTLTATNPGGFAKHIFNVKVL--DRPGPPEGPLAV 15067
Score = 39.9 bits (89), Expect = 0.16
Identities = 73/313 (23%), Positives = 117/313 (37%), Gaps = 34/313 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V + + + W D + ++ Y VE + G RW++ L
Sbjct: 15157 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER---RDKAGQRWIKCNKKTLT 15213
Query: 3007 S--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
+ L +G EY FR+ N G S TS +P PG ++L
Sbjct: 15214 DLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG----PPGNPRVL- 15268
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVE-----EEAGRMTSQFNGFDCC-LTIKDINID 3117
+T+ + S+ KP+ G+ VE E+ ++ + G TI + +
Sbjct: 15269 -DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTEN 15327
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
E + A N+ G + T D L E E++ D T+R
Sbjct: 15328 QEYKIRIYAMNSEGLGEP-----ALVPGTPKAEDRMLPPE--IELDADLRKVVTIR---- 15376
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
A +RL + G P P+V W +D E + DK + + L + N D G
Sbjct: 15377 ---ACCTLRLFVPIKGRPDPEVKWARDHGESL-DKASIE-SASSYTLLIVGNVNRFDSGK 15431
Query: 3238 YEVTARNNSGAVS 3250
Y +T N+SG+ S
Sbjct: 15432 YILTVENSSGSKS 15444
Score = 39.9 bits (89), Expect = 0.16
Identities = 23/79 (29%), Positives = 38/79 (48%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A +++ + G P PKV+ +DG + R N + T+ + + D G Y
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20050
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
E+TA N+SG +VV
Sbjct: 20051 EITAANSSGTTKAFINIVV 20069
Score = 39.9 bits (89), Expect = 0.16
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
E L+ + G LR+ V P +TW + G+ L + RAI+ + L
Sbjct: 22950 ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSL-LI 23006
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ V DAG YT A N+ G+ S + V+V T
Sbjct: 23007 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDT 23040
Score = 39.9 bits (89), Expect = 0.16
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 2949 RIPGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP- 3004
RIPG P + D + ++L W + + V Y VE + A+ RWV + P
Sbjct: 23433 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD---RWVRVNKVPV 23489
Query: 3005 -LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
+ + + L +G EY RVT N G G+ S+ S I
Sbjct: 23490 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 23527
Score = 39.5 bits (88), Expect = 0.21
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 9/141 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E V C V ++ W+RN + + KY D + TL + +A
Sbjct: 6149 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207
Query: 2660 DSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D A Y+ ++ N G + ++ANL V E + ++D + + + C++
Sbjct: 6208 DQANYNVSLTNHRGENVKSAANLIV----EEEDL--RIVEPLKDIETMEKKSVTFWCKVN 6261
Query: 2719 GQPLPKITWFKDDKQIPSDGR 2739
+ + W K+ +++P D R
Sbjct: 6262 RLNV-TLKWTKNGEEVPFDNR 6281
Score = 39.5 bits (88), Expect = 0.21
Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 7/121 (5%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL 2634
E+R VI +++T+ + ++ + A G +K+ V+ PTVTW + +L
Sbjct: 14553 ESRPVIVKEQTMLPELDLRGIYQKLVI---AKAGDNIKVEIPVLGRPKPTVTWKKGDQIL 14609
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
+ + L + V SDS Y T N G + ++V+ P PP
Sbjct: 14610 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHD----IPGPP 14665
Query: 2695 T 2695
T
Sbjct: 14666 T 14666
Score = 39.5 bits (88), Expect = 0.21
Identities = 22/76 (28%), Positives = 32/76 (42%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G K+ + PT+ W + L N + K D +L V +AV DS Y
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 2668 VENENGAISTSANLKV 2683
+N G S + N+KV
Sbjct: 16121 AKNVAGERSVTVNVKV 16136
Score = 39.5 bits (88), Expect = 0.21
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
Y + G++L+I V P ++W +DG L+ + R + + L + D
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LHIKEGNKDDF 17882
Query: 3337 GVYTCTASNEVGRASTSGKVEVI 3359
G YT TA+N G A+ + V V+
Sbjct: 17883 GKYTVTATNSAGTATENLSVIVL 17905
Score = 39.5 bits (88), Expect = 0.21
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
++A +RL V G PPP ++W K G ++ R E + L + N D G Y
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDAGKY 23018
Query: 3239 EVTARNNSGAVS 3250
+ A N SG S
Sbjct: 23019 TIEAENQSGKKS 23030
Score = 39.5 bits (88), Expect = 0.21
Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 9/151 (5%)
Query: 3225 LEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-- 3280
LE T+L++G Y + A+N G + V P P +H
Sbjct: 23195 LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 23254
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
G + + + P +W+ G +LR S R +T++ ++ +L + T RD G Y
Sbjct: 23255 AGRPVELVIPIAGRPPPAASWFFAGSKLRESER--VTVETHTKVAKLTIRETTIRDTGEY 23312
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T N G +TS ++VI D+ P P
Sbjct: 23313 TLELKNVTG--TTSETIKVIILDKPGPPTGP 23341
Score = 39.5 bits (88), Expect = 0.21
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 8/152 (5%)
Query: 3281 EGDELRISAVVEAYP-SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
EG ++ +E Y S VTWY +L S + +T + DG L + +T D G Y
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGTY 25142
Query: 3340 TCTASNEVGRASTSGKVEVIGT----DQTSEPRIPPVVISPDVP--YSKEPMFIRKPRSS 3393
C N+ G S+ ++ V G D + + D + P F +
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25202
Query: 3394 EAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
A G+ V + P+P V W + K++
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIK 25234
Score = 39.1 bits (87), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+F ++D +V C+V P V W KD +E+ R +++ H L I
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIP 3071
Query: 3229 PTNLDDGGVYEVTARNN 3245
T + D G Y V A N
Sbjct: 3072 STRMSDAGKYTVVAGGN 3088
Score = 39.1 bits (87), Expect = 0.28
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L ++ G A +V G+P P V W K ++
Sbjct: 3575 PHFLKELK-PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 3633
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
+ D +D G Y C+A N G+++ A L V+ + T D K + + E D+P
Sbjct: 3634 IVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM-TDTPCKAKSTPEAPEDFP 3690
Score = 39.1 bits (87), Expect = 0.28
Identities = 75/325 (23%), Positives = 124/325 (38%), Gaps = 36/325 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--- 3007
PG+P V+ + ++W +P+ Y +E EG W + P+
Sbjct: 9105 PGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEK---REEGSPYWSRVSRAPITKVGL 9161
Query: 3008 ----FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL 3063
F+ L +G +Y FR N G G S+ S +AGD P F P ++
Sbjct: 9162 KGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP---EVAGD-PIFPPGPPSCPEVK 9217
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
++++ K G +K G+ VE + T K +N D+ +
Sbjct: 9218 DKTKSSISLGWKPPAKDGGSPIK-GYIVEMQEEGTTDW----------KRVNEPDKLITT 9266
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEAD-AKLKRERSAEVEGDYPPQFT-MRLRDRRV-Q 3180
CE + K R V E++ + E A + P F + +D V +
Sbjct: 9267 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCK 9326
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDG--EEVVYDKRRNKYQDEQFHTLE------IAPTNL 3232
A +R+ + G P PK SW DG ++ + D + +D Q T E I
Sbjct: 9327 AGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKR 9386
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVV 3257
G Y +TA+N +G + +C + V
Sbjct: 9387 SHTGKYSITAKNKAGQKTANCRVKV 9411
Score = 39.1 bits (87), Expect = 0.28
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 3167 PPQFTMRLRDRRV---QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ M ++ R V +A +++ + G P P +SW KDG E+ R +
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19348
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSG--AVSCHCGLVVDK 3259
L + D G Y +T +N +G +V+ +C V+DK
Sbjct: 19349 LLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNC-KVLDK 19385
Score = 38.7 bits (86), Expect = 0.36
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRV 3023
V L W D +P+ Y VE + + + ++ +T L F +L QG+EY F+V
Sbjct: 7007 VHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDF-VTDLE-FTVPDLVQGKEYLFKV 7064
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPE 3051
RN+ G GE + + + P+
Sbjct: 7065 CARNKCGPGEPAYVDEPVNMSTPATVPD 7092
Score = 38.3 bits (85), Expect = 0.48
Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 11/178 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE--VTARNNSGAV- 3249
G P K + EE D +R D+ T E NL + Y V A N +G
Sbjct: 9235 GGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESE 9294
Query: 3250 -SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
S G + I+ G + G ++RI AV++ P+ +W DG
Sbjct: 9295 PSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAK 9354
Query: 3309 RPSRRAIMTLDRDGQIELA-------LAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ + + + D Q+E A + G Y+ TA N+ G+ + + +V+V+
Sbjct: 9355 KAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVM 9412
Score = 38.3 bits (85), Expect = 0.48
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 11/125 (8%)
Query: 2947 PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P +P EP V + + +AW + D +P++ Y +E WV+ T
Sbjct: 12591 PFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER---KERNSLLWVKANDT 12647
Query: 3004 PLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGD---RPEFVDILPG 3058
+ S + L +G EY FR+ N+ G S+ + + + D +PE +D+
Sbjct: 12648 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKS 12707
Query: 3059 QLKIL 3063
+ ++
Sbjct: 12708 TVSLI 12712
Score = 38.3 bits (85), Expect = 0.48
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 7/133 (5%)
Query: 2659 SDSAEYSCTV--ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAE--NELVLE 2714
++ EY+ V ENENG T + + V + P + + D +LA+ + L+
Sbjct: 13449 TEGKEYTFRVSAENENGE-GTPSEITVVARDDVVA-PDLDLKGLPDLCYLAKENSNFRLK 13506
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
I+G+P P ++W K + + +D R A + D D+G YT +N
Sbjct: 13507 IPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYD-CQKSDAGKYTITLKNVAG 13565
Query: 2775 TDQITHFVNFTGR 2787
T + T + G+
Sbjct: 13566 TKEGTISIKVVGK 13578
Score = 38.3 bits (85), Expect = 0.48
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 8/145 (5%)
Query: 2663 EYSCTVENENGAIST-SANLKVYPSFEASPIPP-TFTRSIRDTFHLAENELV-LECRIRG 2719
E+ +N GAIS S + + + +P + RDT + E LE + G
Sbjct: 17095 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 17154
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
+PLP I W + DK+I R + D L + + D G Y +A N +
Sbjct: 17155 KPLPTIEWLRGDKEIEESARCE-IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFP 17213
Query: 2780 HFVNFTGR----ESQVSPNVVTAEK 2800
V R E V VT+EK
Sbjct: 17214 VNVKVLDRPGPPEGPVQVTGVTSEK 17238
Score = 37.9 bits (84), Expect = 0.64
Identities = 42/166 (25%), Positives = 76/166 (45%), Gaps = 20/166 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV---DGLIT 2650
P F+ L D T VE V L C IS +D V W+++G ++K K V DG
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCE-ISKADAPVKWFKDG----KEIKPSKNAVIKTDGKKR 5575
Query: 2651 LEVL-NAVPSDSAEYSCT--VENENGAIS-TSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
+ +L A+ SD +Y+C + +G + +K+ + + T T R +
Sbjct: 5576 MLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETET--ARFETEI 5633
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
+E+++ +++G+ L + D +I +G+ + L + CRL
Sbjct: 5634 SEDDIHANWKLKGEALLQ----TPDCEIKEEGKIHSLVLHN--CRL 5673
Score = 37.9 bits (84), Expect = 0.64
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 3278 KLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDR----DGQIELALAAVT 3332
K+ G+ + I A V P + W ++ + +P+ +T + + + EL++
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
D G YT TASN +G + VEV D+ S PR
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVY--DRPSPPR 9005
Score = 37.9 bits (84), Expect = 0.64
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
R++ ++ +RL+ + G P PKV+W K+ + R + LEI +D
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARID--VTPVGSKLEIRNAAHED 10786
Query: 3235 GGVYEVTARNNSGAVSCHCG-LVVDK 3259
GG+Y +T N +G+ + LV+DK
Sbjct: 10787 GGIYSLTVENPAGSKTVSVKVLVLDK 10812
Score = 37.9 bits (84), Expect = 0.64
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G ++L V P VTW + G+ DN + K + LVD + L + N+ DS +YS
Sbjct: 12124 GCPIRLFAIVRGRPAPKVTWRKVGI--DNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSL 12181
Query: 2667 TVENENGAISTSANLKV 2683
T+ N G + N++V
Sbjct: 12182 TLVNPAGEKAVFVNVRV 12198
Score = 37.9 bits (84), Expect = 0.64
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 7/97 (7%)
Query: 2677 TSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS 2736
T L + P + S IP + T + N + LE +G+P P I+W KD +
Sbjct: 21056 TVKELIITPEVDLSDIP-----GAQVTVRIGHN-VHLELPYKGKPKPSISWLKDGLPL-K 21108
Query: 2737 DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ + F + L+I N E G YT +N+V
Sbjct: 21109 ESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV 21145
Score = 37.5 bits (83), Expect = 0.84
Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ L+I+A + P ++W +DG+ + R + + D L + RD G Y
Sbjct: 19307 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIRRDTGQYVL 19365
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T N G S + +V+ D+ P P
Sbjct: 19366 TLKNVAGTRSVAVNCKVL--DKPGPPAGP 19392
Score = 37.1 bits (82), Expect = 1.1
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
CR+ G P PK+ W+ + + I R++ Y DG+ L I + D+G AEN
Sbjct: 1816 CRVTGYPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAEN 1870
Score = 37.1 bits (82), Expect = 1.1
Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
P+F L DY + LQ EI V+W ++G+ + + +NA + + L L
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEI-KPSKNAVIKTDGKKRMLIL 5579
Query: 2873 SDVTETESGLYTCRAWS--AHGNVDM-NAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
+++ G YTC + G +D+ + I +V+P R E +I +
Sbjct: 5580 KKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEI---SED 5636
Query: 2930 DINISFRTQGE 2940
DI+ +++ +GE
Sbjct: 5637 DIHANWKLKGE 5647
Score = 37.1 bits (82), Expect = 1.1
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW--VELGITPLNSF 3008
PG P V + ++++W + +P+L Y VE G W V + P N F
Sbjct: 14765 PGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVER---KERNGILWQTVSKALVPGNIF 14821
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTS 3038
+ L G Y FRV N G + S+ S
Sbjct: 14822 KSSGLTDGIAYEFRVIAENMAGKSKPSKPS 14851
Score = 37.1 bits (82), Expect = 1.1
Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 3/83 (3%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQ 3015
V D + V+L W + + + Y VE AE RW+ +G + NL
Sbjct: 24633 VSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAE---RWLRVGQARETRYTVINLFG 24689
Query: 3016 GEEYHFRVTPRNRYGWGESSQTS 3038
Y FRV N++G + S+ S
Sbjct: 24690 KTSYQFRVIAENKFGLSKPSEPS 24712
Score = 37.1 bits (82), Expect = 1.1
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL--VDGLITL 2651
P +D + EG + + C+ P VTW G + ++ + R + D L TL
Sbjct: 26832 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 26891
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+++ D Y+ ++ NE G+ S + N+ +
Sbjct: 26892 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 36.7 bits (81), Expect = 1.5
Identities = 23/79 (29%), Positives = 32/79 (40%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A VR + G P P W DG E+ D+ D L I D G Y
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
++T N +G+ + L V
Sbjct: 11085 QITVSNAAGSKTVAVHLTV 11103
Score = 36.7 bits (81), Expect = 1.5
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 3167 PPQFTMRLRDRRV---QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ + R+V +A+ +RL + G P P+V W K E ++ D+ + + F
Sbjct: 18607 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEV-TSSFT 18664
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGA 3248
L I D G Y +T NNSG+
Sbjct: 18665 MLVIDNVTRFDSGRYNLTLENNSGS 18689
Score = 36.7 bits (81), Expect = 1.5
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 7/125 (5%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A L L I+G+P P++ W K + + + + + L IDN T DSG Y
Sbjct: 18624 ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIE---VTSSFTMLVIDNVTRFDSGRYN 18680
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHF--GNVLTDYQV 2824
EN+ + T FVN +S +P +T + + +L P G +T+Y V
Sbjct: 18681 LTLENN--SGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIV 18738
Query: 2825 ARGGT 2829
+ T
Sbjct: 18739 EKRET 18743
Score = 36.7 bits (81), Expect = 1.5
Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ ++L SV P +TW + G+ L ++ L+ ++ +N D+ +Y+
Sbjct: 22964 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY--DAGKYTIE 23021
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSI-RDT 2703
EN++G S + +KVY + P P + + RD+
Sbjct: 23022 AENQSGKKSATVLVKVYDT--PGPCPSVKVKEVSRDS 23056
Score = 36.3 bits (80), Expect = 1.9
Identities = 14/38 (36%), Positives = 22/38 (57%)
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+P+F+ KP S + EG + +VVG P P+ +W D
Sbjct: 1410 KPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHD 1447
Score = 36.3 bits (80), Expect = 1.9
Identities = 64/299 (21%), Positives = 108/299 (36%), Gaps = 40/299 (13%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDC 3107
+P FV+ L + I G + G P P +VW+KN V + ++ + +
Sbjct: 1509 KPMFVEKLKN-VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1567
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL----KRERSAEV- 3162
L I D Y+ A N G+ +T ++ V + E + KL R+ E+
Sbjct: 1568 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1627
Query: 3163 -----------------EGD-------YPPQFTMRLRDRRVQATYPVRLTCQV--IGSPP 3196
EGD P F +L R++ P C++ I P
Sbjct: 1628 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPISDPT 1687
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
V W DG+ + R + + +L+ D G+ A N G L+
Sbjct: 1688 MVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Query: 3257 V--DKG-IRAYVAPEFCCGLEPLYKL----HEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
V +K + PE GL+ + +L HEG ++ + + Y + VR+
Sbjct: 1748 VKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1806
Score = 36.3 bits (80), Expect = 1.9
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 3049 RPEFVDILPG--QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
+P + IL G K+ G+ L V + V GV WMK+G EV + + R+ +
Sbjct: 2306 KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEV-QPSDRVHIVIDKQS 2363
Query: 3107 CCLTIKDINIDDEGRYS----CEATNTHGKASTYA 3137
L I+D+ +D G YS +T G+ S Y+
Sbjct: 2364 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS 2398
Score = 36.3 bits (80), Expect = 1.9
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EFV+ L Q + + A +C + + V W +NG E++E + + +G L
Sbjct: 6327 EFVEHLEDQT-VTEFDDAVFSCQLSREKA-NVKWYRNGREIKE-GKKYKFEKDGSIHRLI 6383
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTY 3136
IKD +DDE Y+C + +A +
Sbjct: 6384 IKDCRLDDECEYACGVEDRKSRARLF 6409
Score = 36.3 bits (80), Expect = 1.9
Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
R++G+P P ITW K+ K + + R V L I D G Y A+NS
Sbjct: 11434 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADHGKYIISAKNSSGH 11492
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Q + VN R VT S E+ + G+ +T++ V
Sbjct: 11493 AQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11541
Score = 36.3 bits (80), Expect = 1.9
Identities = 46/162 (28%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 2653 VLNAVPSDSAEYSCTVENENGAIS----TSANLKVYPSFEASPIPPTFTRSIRDTFHL-A 2707
V + V E+ +N GAIS ++ + +EA I +I+D + A
Sbjct: 13838 VTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTI--VLDPTIKDGLTIKA 13895
Query: 2708 ENELVLEC-RIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ +VL I G+PLPK +W K K I PSD L I T +D+G Y
Sbjct: 13896 GDTIVLNAISILGKPLPKSSWSKAGKDIRPSD--ITQITSTPTSSMLTIKYATRKDAGEY 13953
Query: 2766 TCKAENSVWTDQITH----FVNFTGRESQVSPNVVTAEKTRI 2803
T A N T ++ H ++ G V + V+AEK +
Sbjct: 13954 TITATNPFGT-KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 13994
Score = 36.3 bits (80), Expect = 1.9
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVV-YDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
RL V G PPP + W KDG+E+ K K D + + T D G Y +TA N
Sbjct: 14983 RLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDSGAYTLTATN 15041
Query: 3245 NSG 3247
G
Sbjct: 15042 PGG 15044
Score = 36.3 bits (80), Expect = 1.9
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A +L +E + G+P P I+W KD + + R A L I +D G YT
Sbjct: 17828 AGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LHIKEGNKDDFGKYT 17886
Query: 2767 CKAENSVWT 2775
A NS T
Sbjct: 17887 VTATNSAGT 17895
Score = 36.3 bits (80), Expect = 1.9
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 9/123 (7%)
Query: 2662 AEYSCTVENEN--GAI--STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
AEY V++ N GA S S++ ++ E P+ + + A +
Sbjct: 19654 AEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPF 19713
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFY-LADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
RG+P+P + W K D +D R +A+ D L I+N DSG YT +N +
Sbjct: 19714 RGRPVPNVLWSKPD----TDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19769
Query: 2777 QIT 2779
+T
Sbjct: 19770 SLT 19772
Score = 35.9 bits (79), Expect = 2.6
Identities = 37/168 (22%), Positives = 59/168 (35%), Gaps = 3/168 (1%)
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTF--TRSIRDTFHLAENELVLECRIRGQP 2721
Y N GA S + + + P F + + A ++ L + G+P
Sbjct: 7162 YRVKTLNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7221
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKITW K D + D R + +D+ D+GTY +A N
Sbjct: 7222 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR-SDTGTYIIEAVNVCGRATAVVE 7280
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
VN + + +T + R G+ +T+Y V R T
Sbjct: 7281 VNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRAT 7328
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/76 (27%), Positives = 31/76 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L V PT+ W ++G L+ K K+ D L ++ DS Y+ T
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 2668 VENENGAISTSANLKV 2683
N G N+KV
Sbjct: 15039 ATNPGGFAKHIFNVKV 15054
Score = 35.9 bits (79), Expect = 2.6
Identities = 24/102 (23%), Positives = 38/102 (37%), Gaps = 4/102 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F T + G +K+ I P VTW+++ V L + + + L +
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15710
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT 2695
+A D Y + N G + N+ V P PPT
Sbjct: 15711 KDACREDVGHYVVKLTNSAGEAIETLNVIVLD----KPGPPT 15748
Score = 35.9 bits (79), Expect = 2.6
Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 8/113 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+P +T ++ + A + L I G+P P I W+KDDK++ ++ D +
Sbjct: 20377 LPLEYTEVVK---YRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LAS 20432
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVVTAEK 2800
+ I + +SG Y K N++ + T V + + VTAEK
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMASASATIRVQILDKPGPPGGPIEFKTVTAEK 20485
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPS--DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
L + C G+P P++TW ++I S GR+ D + L I + +D G YT
Sbjct: 26849 LTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFH-IENTDDLTTLIIMDVQKQDGGLYTLS 26907
Query: 2769 AENSVWTDQIT 2779
N +D T
Sbjct: 26908 LGNEFGSDSAT 26918
Score = 35.5 bits (78), Expect = 3.4
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERS 3159
+G D KD I +Y EA HGK L ++ D + + A + +
Sbjct: 2513 SGIDVLWNFKDKEIKPSSKYKIEA---HGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKL 2569
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
G + L D+ V + C+V +P K W +DG+ + D
Sbjct: 2570 TVAGG----AISKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESD 2624
Query: 3220 EQFHTLEIAPTNLDDGGVY 3238
L IA T LDD G Y
Sbjct: 2625 GHKRRLIIAATKLDDIGEY 2643
Score = 35.5 bits (78), Expect = 3.4
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
+AN K + + +P F + D ++E EC + +P W K ++I D
Sbjct: 5327 AANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGD 5385
Query: 2738 GRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAEN 2771
R++ + DG + I + ED Y +AE+
Sbjct: 5386 DRFE--LIKDGTKHSMVIKSAAFEDEAKYMFEAED 5418
Score = 35.5 bits (78), Expect = 3.4
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPI--PPTFTRSIRDTFHLAENELVLECRI 2717
+ EY V EN A + + P+ PI P R+ + +E+ L+ I
Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKR--GDEIALDASI 8206
Query: 2718 RGQPLPKITWFKDDKQI 2734
G P P ITW KD+ I
Sbjct: 8207 SGSPYPTITWIKDENVI 8223
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+RG+P PK+TW K I + R L D + L I N T +DSG Y+ N
Sbjct: 12133 VRGRPAPKVTWRK--VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVN 12185
Score = 35.5 bits (78), Expect = 3.4
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 3/55 (5%)
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+G+P+P+ITW +++ + + + +L+IDN D+G Y K ENS
Sbjct: 17552 KGRPMPEITWSREEGEFTDKVQIEK---GVNYTQLSIDNCDRNDAGKYILKLENS 17603
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ +G +R++ ++ P W ++G + S+RA++ + EL + D+G
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATS-ETHTELVIKEADRGDSGT 23707
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSE 3366
Y N+ G+ + KV VIG+ + E
Sbjct: 23708 YDLVLENKCGKKAVYIKVRVIGSPNSPE 23735
Score = 35.5 bits (78), Expect = 3.4
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+RLT + G P P W K+G+++ KR E L I + D G Y++ N
Sbjct: 23657 IRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 23714
Query: 3245 NSG 3247
G
Sbjct: 23715 KCG 23717
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+ KPRS EG++ C+ G+P P V WLR
Sbjct: 26067 LTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + + G + EI G P+ +EW + ++ + N + + +Y
Sbjct: 26634 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS-ISSNVSISRSRNVY 26692
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L + + + ++SG YT +A + G A++ V+
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
T R+P V P P P + ++ EG++V +EC + G P P V W R+
Sbjct: 881 TETARVPAPVEIPVTP----PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRE 933
Score = 35.1 bits (77), Expect = 4.5
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 8/106 (7%)
Query: 2950 IPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
+PG P + D VSL W + A + Y +E + + RW
Sbjct: 6693 VPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIE---LRDKTSIRWDTAMTVRAE 6749
Query: 3007 SFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP 3050
A ++ +G+EY FRV +NR G G+ S + + V +RP
Sbjct: 6750 DLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 6795
Score = 35.1 bits (77), Expect = 4.5
Identities = 21/69 (30%), Positives = 30/69 (43%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A + L V G P PK++W K + DKR + T+ I + D G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264
Query: 3239 EVTARNNSG 3247
+ A N G
Sbjct: 7265 IIEAVNVCG 7273
Score = 35.1 bits (77), Expect = 4.5
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 2997 WVELGIT-PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
W ++ T P+ S L +G EY FR+ N+YG G+ T +I
Sbjct: 12938 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAI 12983
Score = 35.1 bits (77), Expect = 4.5
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A L L I+G+P P++ W K D +I + L +DN DSG YT
Sbjct: 16459 AGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID---VTSSFTSLVLDNVNRYDSGKYT 16515
Query: 2767 CKAENSVWT 2775
ENS T
Sbjct: 16516 LTLENSSGT 16524
Score = 35.1 bits (77), Expect = 4.5
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KP FS++ + G +K+ + PT+TW ++G+ L + L TL
Sbjct: 16736 KPAFSSY----SVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLS 16791
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL 2681
+ D +Y TV N G + S +
Sbjct: 16792 IKETHKDDGGQYGITVANVVGQKTASIEI 16820
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/55 (32%), Positives = 25/55 (45%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
G PPP V+W KD + + D R + + L I +D G Y +T N G
Sbjct: 20800 GRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854
Score = 35.1 bits (77), Expect = 4.5
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +++ V P VTW+++GV ++ ++ V G +L V +A Y T
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVY--T 21533
Query: 2668 VENENGAISTSANLKV 2683
VE +N + S A +KV
Sbjct: 21534 VEAKNASGSAKAEIKV 21549
Score = 34.7 bits (76), Expect = 5.9
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYT 3340
G LRI AVV P W ++ L R + +D G + EL + +D G Y
Sbjct: 8622 GKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKDHGRYV 8678
Query: 3341 CTASNEVGRASTSGKVEV 3358
TA+N G + +VEV
Sbjct: 8679 ITATNSCGSKFAAARVEV 8696
Score = 34.7 bits (76), Expect = 5.9
Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 2951 PGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN- 3006
PG P V D L+W + APV Y +E + WV +
Sbjct: 19781 PGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKA---WVSVTNNCNRL 19837
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE 3051
S+ NL++G Y+FRV+ N +G G ++T + + PE
Sbjct: 19838 SYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 19882
Score = 34.7 bits (76), Expect = 5.9
Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 4/131 (3%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + ++ I G+P PK+TW ++ ++ R D L + + DSG Y
Sbjct: 22164 AGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRT-TLTVKDSMRGDSGRYF 22222
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVS-PNVVTAEKTRIARQSLESRRPHFGNVLTDYQVA 2825
EN+ + V GR V+ P V++ S + G +T+Y V
Sbjct: 22223 LTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVE 22282
Query: 2826 R--GGTIGLQV 2834
+ GT Q+
Sbjct: 22283 KRESGTTAWQL 22293
Score = 34.7 bits (76), Expect = 5.9
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G I + P+ VTW + +RL+ + R +T +D + L + D+G Y
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKD-RTTLTVKDSMRGDSGRYFL 22223
Query: 3342 TASNEVGRASTSGKVEVIG 3360
T N G + S V VIG
Sbjct: 22224 TLENTAGVKTFSVTVVVIG 22242
Score = 34.7 bits (76), Expect = 5.9
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K E +G + P+ DVP + P F + R+ R + C+V G PKP
Sbjct: 24403 KCENLGGESEWSEISEPITPKSDVPI-QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 24461
Query: 3415 VYWLR 3419
V W R
Sbjct: 24462 VKWYR 24466
Score = 34.3 bits (75), Expect = 7.9
Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 15/85 (17%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVE-------SWLIGAEGGARWVELGITPLNSFDAFNLKQG 3016
VSLAW + + ++ Y VE +W++ + A E +T L K G
Sbjct: 6609 VSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDR-AESCEFTVTGLQ-------KGG 6660
Query: 3017 EEYHFRVTPRNRYGWGESSQTSSSI 3041
EY FRV+ RNR G GE +T + +
Sbjct: 6661 VEYLFRVSARNRVGTGEPVETDNPV 6685
Score = 34.3 bits (75), Expect = 7.9
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 3/81 (3%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV-CRL 2752
PT D + +L + R P+P ++W KD K++ + R D + L
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT--MKNDHISAHL 7947
Query: 2753 AIDNPTPEDSGTYTCKAENSV 2773
+ D+G YT EN +
Sbjct: 7948 EVPKSVRADAGIYTITLENKL 7968
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 92.7 bits (220), Expect = 2e-17
Identities = 88/341 (25%), Positives = 131/341 (38%), Gaps = 27/341 (7%)
Query: 3039 SSIGVGLAGDRPEFVDILP--GQLKILAGETAN---LTCSVKG-KPVPGVVWMKNGHEVE 3092
S GV +A + ++I P GQ+ GE C ++ V W ++E
Sbjct: 2778 SQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLE 2837
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--- 3149
+ +G L +KDI D+G Y C+ N +G+ S+YA L V R V++
Sbjct: 2838 NSEKYEITYEDGV-AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYC 2896
Query: 3150 --ADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEE 3207
K+KR + PP+FT+ L ++ VR + P P V+WYK G++
Sbjct: 2897 RRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK 2956
Query: 3208 VVYDKRRNKY---QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
+ KY D+ + L I DD Y V ARN G SC L V
Sbjct: 2957 IKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TL 3011
Query: 3265 VAPEFCCGLEPLYK-------LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMT 3317
P L P++K EG + V P + W +DG L +
Sbjct: 3012 HPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 3071
Query: 3318 LDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ L + D G Y TA+N G S ++V
Sbjct: 3072 HEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 3112
Score = 84.6 bits (200), Expect = 6e-15
Identities = 107/443 (24%), Positives = 174/443 (39%), Gaps = 42/443 (9%)
Query: 2941 PK-PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
PK P PE P V+D + VSL+W + + V Y +E + R +
Sbjct: 1549 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKVVRHNK 1608
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
IT + L EY FR+ +N G E+S S + D+P PG+
Sbjct: 1609 TQITT-TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPS----QPGE 1663
Query: 3060 LKILAGETANLTCSVK------GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
L+IL+ ++T + GK + G W++ + + A + +++ D TI
Sbjct: 1664 LEILSISKDSVTLQWEKPECDGGKEILGY-WVEY-RQSGDSAWKKSNKERIKDKQFTIGG 1721
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
+ E + A N G + RT KL S E G
Sbjct: 1722 LLEATEYEFRVFAENETGLSRPR--------RTAMSIKTKLT---SGEAPG-----IRKE 1765
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
++D + +L+CQ++G P P + WY+ G+E++ ++ D + HTL + +
Sbjct: 1766 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 1825
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG--LEPLYKLHEGDELRISAVV 3291
D GVY A N G V L++ P+F G L+ Y G LR+ +
Sbjct: 1826 DEGVYTCIATNEVGEVETSSKLLLQ------ATPQFHPGYPLKEKYYGAVGSTLRLHVMY 1879
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASNEVGRA 3350
P +TW+ G +L + I + + L + V + AG Y SN G
Sbjct: 1880 IGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV 1938
Query: 3351 STSGKVEVIGTDQTSEPRIPPVV 3373
VE+ D+ +P P V+
Sbjct: 1939 DAILDVEI--QDKPDKPTGPIVI 1959
Score = 79.8 bits (188), Expect = 2e-13
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 5/198 (2%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL---DN 2636
I + R R P F+ L ++TA G V+ ++ +P VTWY++G + DN
Sbjct: 2903 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 2962
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPP 2694
KY + GL L + + D AEY+ N+ G S A L V +P S + P
Sbjct: 2963 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 3022
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
F R + + + E R+ G P P + W KD + + + + L I
Sbjct: 3023 MFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHI 3082
Query: 2755 DNPTPEDSGTYTCKAENS 2772
+ PED+G Y A N+
Sbjct: 3083 RDTLPEDTGYYRVTATNT 3100
Score = 77.0 bits (181), Expect = 1e-12
Identities = 57/204 (27%), Positives = 89/204 (43%), Gaps = 11/204 (5%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGI 3002
P A P + P P V D VSLAW + + + V Y +E + W +
Sbjct: 1256 PIAPPGK-PQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQH---EWTKCNT 1311
Query: 3003 TP--LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFV--DILPG 3058
TP + + +L QG EY FRV N G GE ++ ++ V + P++ +
Sbjct: 1312 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 1371
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + G LT +KGKP P W K G ++ + A TS+ + L IK+ + D
Sbjct: 1372 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH---TELVIKEADRGD 1428
Query: 3119 EGRYSCEATNTHGKASTYARLAVV 3142
G Y N GK + Y ++ V+
Sbjct: 1429 SGTYDLVLENKCGKKAVYIKVRVI 1452
Score = 77.0 bits (181), Expect = 1e-12
Identities = 97/429 (22%), Positives = 181/429 (42%), Gaps = 39/429 (9%)
Query: 2951 PGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW--VELGITPLNS 3007
P P V++ N ++W + + Y VE A+ GA W V I+ + +
Sbjct: 1953 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK--CEAKEGAEWQLVSSAIS-VTT 2009
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
NL + Y+FRV+ +N +G + + SS + + ++P PG+ I A
Sbjct: 2010 CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG----APGKPTITAVTK 2065
Query: 3068 ANLTCSVKGKPVPGVVWMKNGH--EVEEEAGRMTSQFNGF--DCCLTIKDI--NIDDEGR 3121
+ + K G ++N + + E++ + S + ++K++ ++ E R
Sbjct: 2066 DSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 2125
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
CE N G++ + +++ ++D ++ P F LR+ V+
Sbjct: 2126 VKCE--NLGGESEW----SEISEPITPKSDVPIQA-----------PHFKEELRNLNVRY 2168
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYE 3239
L C+V G P P V WY+ G+E++ D + + Q+ + +H L IA DD VY+
Sbjct: 2169 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 2228
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
V A N G+VS L V+ + ++ P+ G+ ++ L G+ + I P +
Sbjct: 2229 VRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHAL-RGEVVSIKIPFSGKPDPVI 2286
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + + + + + R + V +DAG Y A N G + +++V
Sbjct: 2287 TWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV- 2345
Query: 3360 GTDQTSEPR 3368
D PR
Sbjct: 2346 -ADVPDPPR 2353
Score = 71.7 bits (168), Expect = 4e-11
Identities = 56/202 (27%), Positives = 84/202 (41%), Gaps = 7/202 (3%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL- 3005
P PG P V D + VSL W + V+ Y +E + G RW++ T +
Sbjct: 165 PVDAPGRPGVTDVQRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 224
Query: 3006 -NSFDAFNLKQGEEYHFRVTPRNRYG---WGESSQTSSSIGVGLAGDRPEFVDILPGQL- 3060
N F L +G+ Y FRV +N G G S + A + E L G L
Sbjct: 225 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 284
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
I AG L +V GKP P ++W K E+ + +++ Q+ G IK + D G
Sbjct: 285 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSLQYTGKRATAVIKFCDRSDSG 343
Query: 3121 RYSCEATNTHGKASTYARLAVV 3142
+Y+ N G + + V+
Sbjct: 344 KYTLTVKNASGTKAVSVMVKVL 365
Score = 71.7 bits (168), Expect = 4e-11
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 7/187 (3%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS-FD 3009
P P VVD + +SLAW K ++ Y +E + R V T N+ F
Sbjct: 572 PSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR-VHTNATIRNTEFT 630
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP--EFVDILPGQLKILAGET 3067
+LK G++Y FRV N G E S++ + I + P E D L + I AG +
Sbjct: 631 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 690
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L SV G+P P + W K G ++ A T++ L + +N D G+Y+ EA
Sbjct: 691 LRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGKYTIEAE 747
Query: 3128 NTHGKAS 3134
N GK S
Sbjct: 748 NQSGKKS 754
Score = 71.3 bits (167), Expect = 6e-11
Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 17/198 (8%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
GE ++ P P V W K+G +++ + + T + + LTI + DD+ Y
Sbjct: 2931 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEY 2990
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+ A N +G+ S A+L V D+ L+ P F L + Q
Sbjct: 2991 TVVARNKYGEDSCKAKLTVTLHPP--PTDSTLR------------PMFKRLLANAECQEG 3036
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK-YQDEQFHTLEIAPTNLDDGGVYEVT 3241
V +V G PPP + W KDG+ + ++ ++ L I T +D G Y VT
Sbjct: 3037 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 3096
Query: 3242 ARNNSGAVSCHCGLVVDK 3259
A N +G+ SC L V++
Sbjct: 3097 ATNTAGSTSCQAHLQVER 3114
Score = 70.1 bits (164), Expect = 1e-10
Identities = 80/324 (24%), Positives = 135/324 (41%), Gaps = 47/324 (14%)
Query: 2607 EGSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
EG VK C + + T VTWY L+N KY DG+ L V + D Y
Sbjct: 2808 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 2867
Query: 2666 CTVENENGAISTSANL------KVYPSFEASPI---------------PPTFTRSI-RDT 2703
C V N+ G S+ A L +VY + + PP FT + T
Sbjct: 2868 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 2927
Query: 2704 FHLAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLAD-GVCRLAIDNPTPED 2761
++ EN + I P P +TW+K ++I P D + + +D G+ +L I++ T +D
Sbjct: 2928 AYVGEN-VRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 2986
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
YT A N G +S + VT + + RP F +L +
Sbjct: 2987 DAEYTVVARNKY------------GEDSCKAKLTVTLHPP----PTDSTLRPMFKRLLAN 3030
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTET 2878
+ G ++ ++ + G P ++W ++G+ ++ + N + + +GL Y L + D
Sbjct: 3031 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS-LGPNIEI-IHEGLDYYALHIRDTLPE 3088
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITV 2902
++G Y A + G+ A + V
Sbjct: 3089 DTGYYRVTATNTAGSTSCQAHLQV 3112
Score = 70.1 bits (164), Expect = 1e-10
Identities = 57/238 (23%), Positives = 107/238 (44%), Gaps = 23/238 (9%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPL--PKITWFKDDKQIPSDGRYQAFYLADGV 2749
PP T+ ++ A E+ L C + L ++TW+KD K++ +G +Q Y ADG
Sbjct: 3944 PPKITQFLKAE---ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGT 4000
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQIT------HFVNFTGRESQVSPNVVTAEKT-- 2801
L I+N T D G Y C+ T + F + + S++S + +KT
Sbjct: 4001 YELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTE 4060
Query: 2802 -RIARQSLE------SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE-WLREGRSVT 2853
+ R++ S +P L D V+ V+ G P W ++G+++T
Sbjct: 4061 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 4120
Query: 2854 EVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+ + ++ ++G + L + ++SGLYTC ++ G+V + +T+ D + +
Sbjct: 4121 QGGK-YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 4177
Score = 69.3 bits (162), Expect = 2e-10
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 10/207 (4%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRK----PVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+S A S +S++ E+ T + ++ + F T + EG R+ L ++ ++D
Sbjct: 4237 KSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATD-- 4294
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
V W NGV L N +YR + TL + A D +C + + G + +L +
Sbjct: 4295 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL- 4353
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
S E S P ++ + +N L I G+P P+I WFK++ I S +
Sbjct: 4354 -SKELSDAPAFISQPRSQNINEGQNVLFTR-EISGEPSPEIEWFKNNLPI-SISSNVSIS 4410
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ V L I N + DSG YT KA+N
Sbjct: 4411 RSRNVYSLEIRNASVSDSGKYTIKAKN 4437
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/212 (24%), Positives = 88/212 (41%), Gaps = 21/212 (9%)
Query: 3066 ETANLTCSVKGKPVPG--VVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRY 3122
E A LTC V+ + V W K+G +++E G ++ L I ++ D+G Y
Sbjct: 3958 EIAKLTCVVESSVLRAKEVTWYKDGKKLKEN-GHFQFHYSADGTYELKINNLTESDQGEY 4016
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE-------------RSAEVEGDYP-- 3167
CE + G + T + +++ E +K+ R E + P
Sbjct: 4017 VCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPIS 4076
Query: 3168 --PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
P L+D V + + + G P P W KDG+ + + +D+ L
Sbjct: 4077 SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFL 4136
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
EI T+ D G+Y T +N++G+VS C L +
Sbjct: 4137 EIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 4168
Score = 67.3 bits (157), Expect = 9e-10
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 3202 YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI 3261
Y+DG ++Y K K D + ++ +D E+ + +C + K
Sbjct: 2846 YEDGVAILYVKDITKLDDGTYRC-KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIK 2904
Query: 3262 RAYVA-------PEFCCGLEPLYK--LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
R PEF PLY + G+ +R + +P VTWY+ G +++P
Sbjct: 2905 RRTDTMRLLERPPEFTL---PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 2961
Query: 3313 R-AIMTLDRD-GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T + D G +L + +VTT D YT A N+ G S K+ V T P
Sbjct: 2962 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TLHP--- 3013
Query: 3371 PVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P + PMF R ++E +EG +V E V G P P + W +D
Sbjct: 3014 -----PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKD 3058
Score = 66.9 bits (156), Expect = 1e-09
Identities = 51/184 (27%), Positives = 85/184 (46%), Gaps = 4/184 (2%)
Query: 2950 IPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFD 3009
+P + VVD + V+LAW K + + Y +E+ G E + V L T L
Sbjct: 864 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-T 922
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LKILAGET 3067
+L +GE+Y FR+ +N G E +T +++ V P + +P + + + AG
Sbjct: 923 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 982
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L + G+P P W G ++ E+ R+T + + LTI++ I D G Y+ E
Sbjct: 983 VELVIPIAGRPPPAASWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELK 1041
Query: 3128 NTHG 3131
N G
Sbjct: 1042 NVTG 1045
Score = 65.3 bits (152), Expect = 4e-09
Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 6/189 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYR-KKLVDGLITL 2651
P F L + S L C V P V WYR G ++ + LKYR ++ G L
Sbjct: 2155 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 2214
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ + D+ Y N+ G++S +A+L+V + +P T H E+
Sbjct: 2215 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGM--GAVHALRGEV 2271
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
V ++ G+P P ITW K I ++G YQ + + +D+G Y A+
Sbjct: 2272 VSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAK 2331
Query: 2771 NSVWTDQIT 2779
N DQ T
Sbjct: 2332 NRFGIDQKT 2340
Score = 63.7 bits (148), Expect = 1e-08
Identities = 81/354 (22%), Positives = 136/354 (38%), Gaps = 42/354 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KPV T L D T S K PT W ++G + KY+ G LE
Sbjct: 4078 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 4137
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL--KVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+ SDS Y+CTV+N G++S+S L K EA + T I E
Sbjct: 4138 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 4197
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+ + +R + + K++ K +++ L + ++ I + + T E
Sbjct: 4198 EISQKALRSEEI-KMSEAKSQEKLA---------LKEEASKVLISEEVKKSAAT---SLE 4244
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
S+ ++IT + SQ S V T + + T + G +
Sbjct: 4245 KSIVHEEIT-------KTSQASEEVRTHAEIKA--------------FSTQMSINEGQRL 4283
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ I G T V+W+ G +T R V TL + + + G+ TC + +
Sbjct: 4284 VLKANIAGA-TDVKWVLNGVELTN-SEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 4341
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
G V +T+ +L PA + +P I+ G+++ + GEP P+
Sbjct: 4342 EGIVKCQYDLTL--SKELSDAPA-FISQPRSQ-NINEGQNVLFTREISGEPSPE 4391
Score = 60.9 bits (141), Expect = 8e-08
Identities = 76/311 (24%), Positives = 121/311 (38%), Gaps = 20/311 (6%)
Query: 2654 LNAVPSDSAEYSC--TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
LN V S +A SC + ++ G + A +KV S E P+ ++ + +
Sbjct: 2761 LNMVVS-AARISCGGAIRSQKGV--SVAKVKV-ASIEIGPVSGQIMHAVGEE----GGHV 2812
Query: 2712 VLECRIRG-QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
C+I ++TW+ +Q+ + +Y+ Y DGV L + + T D GTY CK
Sbjct: 2813 KYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYRCKVV 2871
Query: 2771 NSVWTDQITHFVNFTG-RE--SQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
N D + G RE + K R L R P F L + G
Sbjct: 2872 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 2931
Query: 2828 GTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVE--QGLYTLALSDVTETESGLYT 2884
+ V I P V W + G+ + + + E +GLY L ++ VT + YT
Sbjct: 2932 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 2991
Query: 2885 CRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
A + +G A +TV + P D + R + G+ + R G P P
Sbjct: 2992 VVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPP 3051
Query: 2944 KAVPERIPGEP 2954
E+ G+P
Sbjct: 3052 TLKWEK-DGQP 3061
Score = 60.1 bits (139), Expect = 1e-07
Identities = 43/157 (27%), Positives = 69/157 (43%), Gaps = 8/157 (5%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
R+ +S K L+ S P + D T G +L+C ++ P + WYR G L
Sbjct: 1745 RTAMSIKTKLT--SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 1802
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
KY+ TL V+ D Y+C NE G + TS+ L + + + P P
Sbjct: 1803 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP-- 1860
Query: 2697 TRSIRDTFHLA-ENELVLECRIRGQPLPKITWFKDDK 2732
+++ ++ A + L L G+P+P +TWF K
Sbjct: 1861 ---LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK 1894
Score = 58.4 bits (135), Expect = 4e-07
Identities = 75/366 (20%), Positives = 141/366 (38%), Gaps = 53/366 (14%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ + A G+P P +W K+G + + S+ G L I + D G
Sbjct: 4090 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG-GFFLEIHKTDTSDSGL 4148
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADA-KLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
Y+C N+ G S+ +L + + + + +A K+ ++++E+ PQ +
Sbjct: 4149 YTCTVKNSAGSVSSSCKLTI---KAIKDTEAQKVSTQKTSEIT----PQ---------KK 4192
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
A ++ + + S K+S K E++ + +K + + A T+L+ V+E
Sbjct: 4193 AVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKKSAATSLEKSIVHEE 4251
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ + + I+A+ ++EG L + A + + V
Sbjct: 4252 ITKTSQASEEVR----THAEIKAFSTQ---------MSINEGQRLVLKANIAG--ATDVK 4296
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
W +GV L S + Q L + + RD G+ TC + + G
Sbjct: 4297 WVLNGVELTNSEEYRYGVSGSDQT-LTIKQASHRDEGILTCISKTKEGIVKCQ------- 4348
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
D T + S P FI +PRS EG V+ E+ G+P P++ W ++
Sbjct: 4349 YDLTLSKEL-----------SDAPAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKN 4397
Query: 3421 FLKVRI 3426
L + I
Sbjct: 4398 NLPISI 4403
Score = 54.4 bits (125), Expect = 7e-06
Identities = 31/128 (24%), Positives = 50/128 (39%), Gaps = 1/128 (0%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + + GE+A +C G+PVP V W++ G + A + + I +
Sbjct: 3794 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTT-TKYKSTFEISSVQA 3852
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DEG YS N+ GK L + R +A R +S E P R
Sbjct: 3853 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRV 3912
Query: 3177 RRVQATYP 3184
+ + ++P
Sbjct: 3913 KSPEPSHP 3920
Score = 52.4 bits (120), Expect = 3e-05
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query: 2568 HRSKAFSEARSVISEKRTLSRNSTRKPVFSTF----LT---DRTAVEGSRVKLTCSVISS 2620
+ A +E +S E+++L ST + + +T LT T EG + +C
Sbjct: 3755 YEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGE 3814
Query: 2621 SDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENG 2673
PTVTW R G +L +++ T E+ + SD YS VEN G
Sbjct: 3815 PVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 3867
Score = 52.0 bits (119), Expect = 4e-05
Identities = 47/199 (23%), Positives = 78/199 (39%), Gaps = 22/199 (11%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
Q+ I G+ L ++ G V W+ NG E+ +G D LTIK + D
Sbjct: 4274 QMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSE-EYRYGVSGSDQTLTIKQASHRD 4330
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
EG +C + G + D L +E S P F + R +
Sbjct: 4331 EGILTCISKTKEGIVKC-------------QYDLTLSKELSDA------PAFISQPRSQN 4371
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ V T ++ G P P++ W+K+ + + + ++LEI ++ D G Y
Sbjct: 4372 INEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 4431
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
+ A+N G S L+V
Sbjct: 4432 TIKAKNFRGQCSATASLMV 4450
Score = 51.6 bits (118), Expect = 5e-05
Identities = 29/96 (30%), Positives = 40/96 (41%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
D+ P+ T+R+R RV R V P +V WY +G E+ + + T
Sbjct: 3598 DHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 3657
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKG 3260
LEI + DD G Y N G S + L V G
Sbjct: 3658 LEILDCHTDDSGTYRAVCTNYKGERSDYATLDVTGG 3693
Score = 51.6 bits (118), Expect = 5e-05
Identities = 61/312 (19%), Positives = 121/312 (38%), Gaps = 24/312 (7%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
D P F+ P I G+ T + G+P P + W KN + + S+
Sbjct: 4359 DAPAFIS-QPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNV-Y 4416
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I++ ++ D G+Y+ +A N G+ S A L V+ + L+ ++G +
Sbjct: 4417 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 4476
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
Q ++++ + +A++ S + + + E F +E+
Sbjct: 4477 SQ-SVQMSASKQEASFS--------SFSSSSASSMTEMKFASMSAQSMSSMQESF--VEM 4525
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+ ++ G+ +T +S + G+ +GI P L + EG L +
Sbjct: 4526 SSSSF--MGISNMTQLESSTSKMLKAGI---RGI-----PPKIEALPSDISIDEGKVLTV 4575
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR-DGQIELALAAVTTRDAGVYTCTASNE 3346
+ P+ VTW G ++ + ++ D L + V +D G+YT + NE
Sbjct: 4576 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 4635
Query: 3347 VGRASTSGKVEV 3358
G S + + +
Sbjct: 4636 FGSDSATVNIHI 4647
Score = 50.8 bits (116), Expect = 8e-05
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EE 3093
S TS + G+ G P+ ++ LP + I G+ + C+ G+P P V W G ++ +
Sbjct: 4541 SSTSKMLKAGIRGIPPK-IEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 4599
Query: 3094 EAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
E GR + L I D+ D G Y+ N G S + +
Sbjct: 4600 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 4647
Score = 50.4 bits (115), Expect = 1e-04
Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
TLS+ + P F + + EG V T + P + W++N + +
Sbjct: 4352 TLSKELSDAPAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISR 4411
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT 2703
+ +LE+ NA SDS +Y+ +N G S +A+L V P E P R+ DT
Sbjct: 4412 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE-EPSREVVLRTSGDT 4469
Score = 47.2 bits (107), Expect = 0.001
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 3/112 (2%)
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
E+ ENE G + S P + ++D L C+I G+PL
Sbjct: 1729 EFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 1788
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSV 2773
P I W++ K++ +Y+ +DG L + ED G YTC A N V
Sbjct: 1789 PDIKWYRFGKELIQSRKYK--MSSDGRTHTLTVMTEEQEDEGVYTCIATNEV 1838
Score = 47.2 bits (107), Expect = 0.001
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 4/116 (3%)
Query: 2660 DSAEYSCTVENEN-GAISTSANLK--VYPSFEASPIPPTFTRSIRDTFHLAENELVLECR 2716
+ EY V+ EN G S + + + P + P F +R+ ++ L C+
Sbjct: 2118 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 2177
Query: 2717 IRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ G P P + W++ K+I +DG +Y+ G +L I + T +D+ Y +A N
Sbjct: 2178 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATN 2233
Score = 46.0 bits (104), Expect = 0.002
Identities = 58/240 (24%), Positives = 102/240 (42%), Gaps = 27/240 (11%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
L +G ++FRV P N YG GE +TS ++ L + P ++P +L+++ + +T
Sbjct: 828 LVEGTMHYFRVLPENIYGIGEPCETSDAV---LVSEVP----LVPAKLEVVDVTKSTVTL 880
Query: 3073 SVKGKPVPGVVWMKNGHEVEE-EAG--RMTSQFNGFDCCL--TIKDINIDDEGRYSCEAT 3127
+ + KP+ G+ +E +AG R L T+ +N ++ + A
Sbjct: 881 AWE-KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQ 939
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G + + VT + D ++ ++ PQ T+ V A PV L
Sbjct: 940 NEKGVSEPRETVTAVTVQ-----DLRVL----PTIDLSTMPQKTIH-----VPAGRPVEL 985
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
+ G PPP SW+ G ++ +R + L I T + D G Y + +N +G
Sbjct: 986 VIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 1045
Score = 46.0 bits (104), Expect = 0.002
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
++ G+ +V+ KP V W NG E++E + + +G L I D + DD G
Sbjct: 3611 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGV-LTLEILDCHTDDSG 3669
Query: 3121 RYSCEATNTHGKASTYARLAV 3141
Y TN G+ S YA L V
Sbjct: 3670 TYRAVCTNYKGERSDYATLDV 3690
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 18/140 (12%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS----- 3353
VTWY+DG +L+ + DG EL + +T D G Y C S E G + T+
Sbjct: 3976 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 4035
Query: 3354 -------GKVEVIGTDQTSEPRIPPVVISPDV------PYSKEPMFIRKPRSSEAREGDT 3400
KV I + S+ + ++ P S +P+ + + +
Sbjct: 4036 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSV 4095
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
+ G+P+P W +D
Sbjct: 4096 AKFAVKATGEPRPTAIWTKD 4115
Score = 45.6 bits (103), Expect = 0.003
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 6/162 (3%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V W +G E+ + TL I + D G+ ++ G V C L +
Sbjct: 4295 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 4354
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
K + AP F ++EG + + + PS + W+++ + + S ++
Sbjct: 4355 KELSD--APAFISQPRS-QNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISR 4411
Query: 3319 DRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
R+ +E+ A+V+ D+G YT A N G+ S + + V+
Sbjct: 4412 SRNVYSLEIRNASVS--DSGKYTIKAKNFRGQCSATASLMVL 4451
Score = 44.4 bits (100), Expect = 0.007
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G R V++ P+ V WY +GV L+ S + T + G + L + T D+G Y
Sbjct: 3615 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRA 3673
Query: 3342 TASNEVGRASTSGKVEVIGTDQTS 3365
+N G S ++V G D T+
Sbjct: 3674 VCTNYKGERSDYATLDVTGGDYTT 3697
Score = 44.4 bits (100), Expect = 0.007
Identities = 25/76 (32%), Positives = 31/76 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G + +V S V WY NGV L K G++TLE+L+ DS Y
Sbjct: 3615 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 3674
Query: 2668 VENENGAISTSANLKV 2683
N G S A L V
Sbjct: 3675 CTNYKGERSDYATLDV 3690
Score = 43.2 bits (97), Expect = 0.017
Identities = 56/205 (27%), Positives = 86/205 (41%), Gaps = 15/205 (7%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---D 2702
D T+ L+ D+ E+ +N G IS + + PP R D
Sbjct: 225 DNFFTVTALSE--GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 282
Query: 2703 TFHL-AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ A ++LVL+ + G+P PKI W K DK++ + Y + I D
Sbjct: 283 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSD 341
Query: 2762 SGTYTCKAENSVWTDQITHFV---NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
SG YT +N+ T ++ V + G +++ + VT EK +A SL + G
Sbjct: 342 SGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLA-WSLP--QEDGGAE 398
Query: 2819 LTDYQVARGGTIGLQ-VEIRG-CPT 2841
+T Y V R T L V + G CPT
Sbjct: 399 ITHYIVERRETSRLNWVIVEGECPT 423
Score = 42.7 bits (96), Expect = 0.022
Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLY-TL 2870
PHF L + V L ++ G P V+W R+G+ + R+ +G Y L
Sbjct: 2155 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 2214
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
++ VT+ ++ +Y RA + G+V A++ V P+ + P + G L GE
Sbjct: 2215 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGMGAVHAL--RGEV 2271
Query: 2931 INISFRTQGEPKP 2943
++I G+P P
Sbjct: 2272 VSIKIPFSGKPDP 2284
Score = 41.9 bits (94), Expect = 0.039
Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 2612 KLTCSVISS--SDPTVTWYRNGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTV 2668
KLTC V SS VTWY++G L ++ DG L++ N SD EY C +
Sbjct: 3961 KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI 4020
Query: 2669 ENENGAISTS 2678
E G T+
Sbjct: 4021 SGEGGTSKTN 4030
Score = 41.5 bits (93), Expect = 0.052
Identities = 28/136 (20%), Positives = 49/136 (36%), Gaps = 1/136 (0%)
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA-EVEGDYPPQFTMRLRDRRVQATY 3183
+ T T S+Y A ++ + L+ + + +++ + + R V
Sbjct: 3744 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGE 3803
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
R +C G P P V+W + G + R + T EI+ D G Y V
Sbjct: 3804 SARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 3863
Query: 3244 NNSGAVSCHCGLVVDK 3259
N+ G L + K
Sbjct: 3864 NSEGKQEAEFTLTIQK 3879
Score = 41.5 bits (93), Expect = 0.052
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 3/120 (2%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
++EG+ R S + P VTW R G L S R +T + + +++V D G
Sbjct: 3799 VYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTK-YKSTFEISSVQASDEGN 3857
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEP-RIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
Y+ N G+ + + T + PP V SP+ P K P ++ P+ ++ E
Sbjct: 3858 YSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPE-PRVKSPEAVKSPKRVKSPE 3916
Score = 39.9 bits (89), Expect = 0.16
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
E L+ + G LR+ V P +TW + G+ L + RAI+ + L
Sbjct: 674 ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSL-LI 730
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ V DAG YT A N+ G+ S + V+V T
Sbjct: 731 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDT 764
Score = 39.9 bits (89), Expect = 0.16
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 2949 RIPGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP- 3004
RIPG P + D + ++L W + + V Y VE + A+ RWV + P
Sbjct: 1157 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD---RWVRVNKVPV 1213
Query: 3005 -LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
+ + + L +G EY RVT N G G+ S+ S I
Sbjct: 1214 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 1251
Score = 39.5 bits (88), Expect = 0.21
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
++A +RL V G PPP ++W K G ++ R E + L + N D G Y
Sbjct: 685 IRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDAGKY 742
Query: 3239 EVTARNNSGAVS 3250
+ A N SG S
Sbjct: 743 TIEAENQSGKKS 754
Score = 39.5 bits (88), Expect = 0.21
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 8/152 (5%)
Query: 3281 EGDELRISAVVEAYP-SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
EG ++ +E Y S VTWY +L S + +T + DG L + +T D G Y
Sbjct: 2808 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGTY 2866
Query: 3340 TCTASNEVGRASTSGKVEVIGT----DQTSEPRIPPVVISPDVP--YSKEPMFIRKPRSS 3393
C N+ G S+ ++ V G D + + D + P F +
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 2926
Query: 3394 EAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
A G+ V + P+P V W + K++
Sbjct: 2927 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIK 2958
Score = 37.1 bits (82), Expect = 1.1
Identities = 37/151 (24%), Positives = 61/151 (40%), Gaps = 9/151 (5%)
Query: 3225 LEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-- 3280
LE T+L++G Y + A+N G + V P P +H
Sbjct: 919 LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 978
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
G + + + P +W+ G +LR S R +T++ ++ +L + T RD G Y
Sbjct: 979 AGRPVELVIPIAGRPPPAASWFFAGSKLRESER--VTVETHTKVAKLTIRETTIRDTGEY 1036
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T N G +T ++VI D+ P P
Sbjct: 1037 TLELKNVTG--TTLETIKVIILDKPGPPTGP 1065
Score = 37.1 bits (82), Expect = 1.1
Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 3/83 (3%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQ 3015
V D + V+L W + + + Y VE AE RW+ +G + NL
Sbjct: 2357 VSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAE---RWLRVGQARETRYTVINLFG 2413
Query: 3016 GEEYHFRVTPRNRYGWGESSQTS 3038
Y FRV N++G + S+ S
Sbjct: 2414 KTSYQFRVIAENKFGLSKPSEPS 2436
Score = 37.1 bits (82), Expect = 1.1
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL--VDGLITL 2651
P +D + EG + + C+ P VTW G + ++ + R + D L TL
Sbjct: 4556 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 4615
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+++ D Y+ ++ NE G+ S + N+ +
Sbjct: 4616 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 4647
Score = 36.7 bits (81), Expect = 1.5
Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ ++L SV P +TW + G+ L ++ L+ ++ +N D+ +Y+
Sbjct: 688 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY--DAGKYTIE 745
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSI-RDT 2703
EN++G S + +KVY + P P + + RD+
Sbjct: 746 AENQSGKKSATVLVKVYDT--PGPCPSVKVKEVSRDS 780
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPS--DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
L + C G+P P++TW ++I S GR+ D + L I + +D G YT
Sbjct: 4573 LTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFH-IENTDDLTTLIIMDVQKQDGGLYTLS 4631
Query: 2769 AENSVWTDQIT 2779
N +D T
Sbjct: 4632 LGNEFGSDSAT 4642
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ +G +R++ ++ P W ++G + S+RA++ + EL + D+G
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATS-ETHTELVIKEADRGDSGT 1431
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSE 3366
Y N+ G+ + KV VIG+ + E
Sbjct: 1432 YDLVLENKCGKKAVYIKVRVIGSPNSPE 1459
Score = 35.5 bits (78), Expect = 3.4
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+RLT + G P P W K+G+++ KR E L I + D G Y++ N
Sbjct: 1381 IRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 1438
Query: 3245 NSG 3247
G
Sbjct: 1439 KCG 1441
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+ KPRS EG++ C+ G+P P V WLR
Sbjct: 3791 LTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 3823
Score = 34.7 bits (76), Expect = 5.9
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K E +G + P+ DVP + P F + R+ R + C+V G PKP
Sbjct: 2127 KCENLGGESEWSEISEPITPKSDVPI-QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 2185
Query: 3415 VYWLR 3419
V W R
Sbjct: 2186 VKWYR 2190
Score = 34.7 bits (76), Expect = 5.9
Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + + G + EI G P+ +EW + ++ + N + + +Y
Sbjct: 4358 SDAPAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPIS-ISSNVSISRSRNVY 4416
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L + + + ++SG YT +A + G A++ V+
Sbjct: 4417 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 4451
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 92.7 bits (220), Expect = 2e-17
Identities = 88/341 (25%), Positives = 131/341 (38%), Gaps = 27/341 (7%)
Query: 3039 SSIGVGLAGDRPEFVDILP--GQLKILAGETAN---LTCSVKG-KPVPGVVWMKNGHEVE 3092
S GV +A + ++I P GQ+ GE C ++ V W ++E
Sbjct: 25054 SQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLE 25113
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--- 3149
+ +G L +KDI D+G Y C+ N +G+ S+YA L V R V++
Sbjct: 25114 NSEKYEITYEDGV-AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYC 25172
Query: 3150 --ADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEE 3207
K+KR + PP+FT+ L ++ VR + P P V+WYK G++
Sbjct: 25173 RRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK 25232
Query: 3208 VVYDKRRNKY---QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
+ KY D+ + L I DD Y V ARN G SC L V
Sbjct: 25233 IKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TL 25287
Query: 3265 VAPEFCCGLEPLYK-------LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMT 3317
P L P++K EG + V P + W +DG L +
Sbjct: 25288 HPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 25347
Query: 3318 LDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ L + D G Y TA+N G S ++V
Sbjct: 25348 HEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 86.2 bits (204), Expect = 2e-15
Identities = 64/197 (32%), Positives = 90/197 (45%), Gaps = 12/197 (6%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKK 2643
TL N+ P L T G + C+VIS P ++WY+ LL K K
Sbjct: 3184 TLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLSTGFKC-KF 3241
Query: 2644 LVDGL-ITLEVLNAVPSDSAEYSCTVENENGAISTSANLK------VYPSFEASPIPPTF 2696
L DG TL ++ A P D+A Y+C +N+ G +TSA+L V P E PP
Sbjct: 3242 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAI 3301
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
++DT +CR+ G L K++W+ DK+I R+ + +L I
Sbjct: 3302 ITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAE 3359
Query: 2757 PTPEDSGTYTCKAENSV 2773
PED GTYT A N+V
Sbjct: 3360 AYPEDEGTYTFVASNAV 3376
Score = 85.0 bits (201), Expect = 4e-15
Identities = 107/443 (24%), Positives = 174/443 (39%), Gaps = 42/443 (9%)
Query: 2941 PK-PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
PK P PE P V+D + VSL+W + + V Y +E + R +
Sbjct: 23825 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNK 23884
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
IT + L EY FR+ +N G E+S S + D+P PG+
Sbjct: 23885 TQITT-TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPS----QPGE 23939
Query: 3060 LKILAGETANLTCSVK------GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
L+IL+ ++T + GK + G W++ + + A + +++ D TI
Sbjct: 23940 LEILSISKDSVTLQWEKPECDGGKEILGY-WVEY-RQSGDSAWKKSNKERIKDKQFTIGG 23997
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
+ E + A N G + RT KL S E G
Sbjct: 23998 LLEATEYEFRVFAENETGLSRPR--------RTAMSIKTKLT---SGEAPG-----IRKE 24041
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
++D + +L+CQ++G P P + WY+ G+E++ ++ D + HTL + +
Sbjct: 24042 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 24101
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG--LEPLYKLHEGDELRISAVV 3291
D GVY A N G V L++ P+F G L+ Y G LR+ +
Sbjct: 24102 DEGVYTCIATNEVGEVETSSKLLLQ------ATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24155
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASNEVGRA 3350
P +TW+ G +L + I + + L + V + AG Y SN G
Sbjct: 24156 IGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV 24214
Query: 3351 STSGKVEVIGTDQTSEPRIPPVV 3373
VE+ D+ +P P V+
Sbjct: 24215 DAILDVEI--QDKPDKPTGPIVI 24235
Score = 83.0 bits (196), Expect = 2e-14
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F +++ G L+ +VI P + W+ NGVLL Y+ +L +
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEA------------------SPIPPT 2695
L D EY+C N+ G SA LK+ E P PP
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
F + ++ + E + G+P P +TWFK++KQ+ + Y + +G ++
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636
Query: 2756 NPTPEDSGTYTCKAEN 2771
+P EDSG Y CKAEN
Sbjct: 3637 DPQREDSGLYICKAEN 3652
Score = 82.2 bits (194), Expect = 3e-14
Identities = 88/358 (24%), Positives = 138/358 (38%), Gaps = 35/358 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITL 2651
KPVF +EG + V+ P W+ +G + N ++ + DG +L
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ A PSDS E++ +N G S S L V + P F +++ ++L
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTV--EAVEHQVKPMFVEKLKNVNIKEGSQL 1527
Query: 2712 VLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
++ R G P P I W K+ D +P G L ID+ +DS YT A
Sbjct: 1528 EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1587
Query: 2771 NSVWTDQITHFVNFTGRESQVSPN---VV---TAEKTRIARQSLE--------------- 2809
N D VN ++ P ++ T IA LE
Sbjct: 1588 NKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGD 1647
Query: 2810 ------SRRPHFGNVLTDYQVARGGTIGLQVEIR--GCPTR-VEWLREGRSVTEVYRNAR 2860
++P F LT ++ R G + + G PT VEWL +G+ + E R
Sbjct: 1648 LYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLR 1706
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G +L +SG+ TCRA + +G +A + V L + + GR
Sbjct: 1707 MINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGR 1764
Score = 80.6 bits (190), Expect = 9e-14
Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 9/185 (4%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG+ ++D N VSL+W K + + +L Y VE + +G +W +
Sbjct: 15555 PGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVE---MQTKGSDKWATCATVKVTEATI 15611
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDILPGQLKILAGETA 3068
L QGEEY FRV+ +N G + Q S + +A D P +L +LAGE
Sbjct: 15612 TGLIQGEEYSFRVSAQNEKGISDPRQLSVPV---IAKDLVIPPAFKLLFNTFTVLAGEDL 15668
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
+ G+P P V W K+ +++ R+ ++ + LTIKD +D G Y + TN
Sbjct: 15669 KVDVPFIGRPTPAVTWHKDNVPLKQTT-RVNAESTENNSLLTIKDACREDVGHYVVKLTN 15727
Query: 3129 THGKA 3133
+ G+A
Sbjct: 15728 SAGEA 15732
Score = 80.2 bits (189), Expect = 1e-13
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 10/196 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P +D ++L W + ++ Y +E +G RWV T ++ +
Sbjct: 21361 PGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEK----RQGNERWVRCNFTDVSECQY 21416
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ---LKILAG 3065
L G+ Y FR+ RN G SS I + + P V+ P L I +G
Sbjct: 21417 TVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSG 21476
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
E+ + V+G+PVP V W K+G E+E+ + G L ++D D G Y+ E
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLG-STSLFVRDATRDHRGVYTVE 21535
Query: 3126 ATNTHGKASTYARLAV 3141
A N G A ++ V
Sbjct: 21536 AKNASGSAKAEIKVKV 21551
Score = 79.8 bits (188), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 79.8 bits (188), Expect = 2e-13
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 5/198 (2%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL---DN 2636
I + R R P F+ L ++TA G V+ ++ +P VTWY++G + DN
Sbjct: 25179 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 25238
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPP 2694
KY + GL L + + D AEY+ N+ G S A L V +P S + P
Sbjct: 25239 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 25298
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
F R + + + E R+ G P P + W KD + + + + L I
Sbjct: 25299 MFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHI 25358
Query: 2755 DNPTPEDSGTYTCKAENS 2772
+ PED+G Y A N+
Sbjct: 25359 RDTLPEDTGYYRVTATNT 25376
Score = 79.4 bits (187), Expect = 2e-13
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD- 3211
+L+ +++E Y P F ++ + R +V+G P P+ W+ DG+++V D
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455
Query: 3212 KRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC 3271
+ +++ +L I P D G + V A+N +G S L V+ + V P F
Sbjct: 1456 THKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE-AVEHQVKPMFVE 1514
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD-RDGQIELALAA 3330
L+ + + EG +L + P+ + W ++ + P + + ++ G+ L + +
Sbjct: 1515 KLKNV-NIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1573
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEV 3358
++D+ YT TA N+ GR +T KV V
Sbjct: 1574 TVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Score = 78.6 bits (185), Expect = 4e-13
Identities = 60/190 (31%), Positives = 87/190 (45%), Gaps = 10/190 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N V+L W K + + Y VE + +G RW++ T + F
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDL-PDG--RWMKASFTNVLETEF 18165
Query: 3009 DAFNLKQGEEYHFRVTPRNRYG-WGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL---A 3064
L + + Y FRV RN G + E S +S +I D P + P ++ A
Sbjct: 18166 TVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN-ASLDPKYKDVIVVHA 18224
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L ++GKP+P VVW K+G E+EE A RM + L +KD D G+Y
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYIL 18284
Query: 3125 EATNTHGKAS 3134
+ +N G S
Sbjct: 18285 KLSNVGGTKS 18294
Score = 77.8 bits (183), Expect = 6e-13
Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 14/217 (6%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDE 3220
V PPQ L+ VQ+ P R + G P PK+SWYK+ E+++ + K+ D
Sbjct: 3187 VNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDG 3245
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP---LY 3277
Q +TL + +D VY A+N+ G + L V+ + V+P+ + P +
Sbjct: 3246 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE--VPEVVSPDQEMPVYPPAIIT 3303
Query: 3278 KLH-----EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L EG R V + V+WY +++PSR MT D +L +A
Sbjct: 3304 PLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAY 3361
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
D G YT ASN VG+ S++ + + + RI
Sbjct: 3362 PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3398
Score = 77.4 bits (182), Expect = 9e-13
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 77.4 bits (182), Expect = 9e-13
Identities = 60/211 (28%), Positives = 94/211 (44%), Gaps = 8/211 (3%)
Query: 2935 FRTQGEPKPKAVPERIPGEPC--VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAE 2992
F +PK P PG P V D + + L W ++ Y V+ L+G
Sbjct: 8490 FSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8549
Query: 2993 GGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF 3052
+R E I + + +++G +Y RV+ N G G +T + V + P
Sbjct: 8550 EWSRCTEKMIK-VRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQP-VTVAEPQEPPAV 8607
Query: 3053 -VDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
+D+ + G ++I+AG+T + V G+PVP VW K E++++ R+ G L
Sbjct: 8608 ELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD--RVVIDNVGTKSELI 8665
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
IKD D GRY ATN+ G AR+ V
Sbjct: 8666 IKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Score = 77.0 bits (181), Expect = 1e-12
Identities = 57/204 (27%), Positives = 89/204 (43%), Gaps = 11/204 (5%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGI 3002
P A P + P P V D VSLAW + + + V Y +E + W +
Sbjct: 23532 PIAPPGK-PQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQH---EWTKCNT 23587
Query: 3003 TP--LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFV--DILPG 3058
TP + + +L QG EY FRV N G GE ++ ++ V + P++ +
Sbjct: 23588 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 23647
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + G LT +KGKP P W K G ++ + A TS+ + L IK+ + D
Sbjct: 23648 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH---TELVIKEADRGD 23704
Query: 3119 EGRYSCEATNTHGKASTYARLAVV 3142
G Y N GK + Y ++ V+
Sbjct: 23705 SGTYDLVLENKCGKKAVYIKVRVI 23728
Score = 77.0 bits (181), Expect = 1e-12
Identities = 97/429 (22%), Positives = 181/429 (42%), Gaps = 39/429 (9%)
Query: 2951 PGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW--VELGITPLNS 3007
P P V++ N ++W + + Y VE A+ GA W V I+ + +
Sbjct: 24229 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK--CEAKEGAEWQLVSSAIS-VTT 24285
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
NL + Y+FRV+ +N +G + + SS + + ++P PG+ I A
Sbjct: 24286 CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG----APGKPTITAVTK 24341
Query: 3068 ANLTCSVKGKPVPGVVWMKNGH--EVEEEAGRMTSQFNGF--DCCLTIKDI--NIDDEGR 3121
+ + K G ++N + + E++ + S + ++K++ ++ E R
Sbjct: 24342 DSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 24401
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
CE N G++ + +++ ++D ++ P F LR+ V+
Sbjct: 24402 VKCE--NLGGESEW----SEISEPITPKSDVPIQA-----------PHFKEELRNLNVRY 24444
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYE 3239
L C+V G P P V WY+ G+E++ D + + Q+ + +H L IA DD VY+
Sbjct: 24445 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 24504
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
V A N G+VS L V+ + ++ P+ G+ ++ L G+ + I P +
Sbjct: 24505 VRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHAL-RGEVVSIKIPFSGKPDPVI 24562
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + + + + + R + V +DAG Y A N G + +++V
Sbjct: 24563 TWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV- 24621
Query: 3360 GTDQTSEPR 3368
D PR
Sbjct: 24622 -ADVPDPPR 24629
Score = 76.6 bits (180), Expect = 1e-12
Identities = 61/219 (27%), Positives = 99/219 (45%), Gaps = 15/219 (6%)
Query: 2946 VPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP- 3004
+P PG+P V+D + VSL W + + ++ Y VE+ + G +WV P
Sbjct: 12691 MPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP---GDKWVRCNTAPH 12747
Query: 3005 ---LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI---LPG 3058
+ A L++ +Y FR R S+ S + + LA + P +D+ +
Sbjct: 12748 QIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTI-LAENVPPRIDLSVAMKS 12806
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINID 3117
L + AG L +V GKP+P V W K+G ++ G +M Q N C L + +N
Sbjct: 12807 LLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN--LCTLELFSVNRK 12864
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
D G Y+ A N+ G S +L V+ D+ A K+ +
Sbjct: 12865 DSGDYTITAENSSGSKSATIKLKVL-DKPGPPASVKINK 12902
Score = 74.5 bits (175), Expect = 6e-12
Identities = 92/369 (24%), Positives = 141/369 (38%), Gaps = 18/369 (4%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++S T G G P F+ P K++ G + C V G P P V W K+G +
Sbjct: 1020 DTSLTEEQAGPGEPA-APYFIT-KPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1077
Query: 3093 EEAGRMTSQFNGF--DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
R +N +C L I DD G Y+ N HG+ S A L + EA
Sbjct: 1078 T-GYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-------LEEA 1129
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +L + E+ Y Q T +++ +V T P + + + + +
Sbjct: 1130 DYELLMKSQQEML--YQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEV-TARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R +D++FH + + + T + VD V F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
++ Y++ EG + + YP + WY+DG R++ R M +DG+ L +
Sbjct: 1248 DLRIKN-YRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI-R 3388
V D G+YT ASN G A SGK+ V P P + S P + R
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 3389 KP-RSSEAR 3396
P R S AR
Sbjct: 1367 SPIRMSPAR 1375
Score = 74.5 bits (175), Expect = 6e-12
Identities = 57/184 (30%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 3201 WYKDGEEVVYD-KRRNKYQDEQ-FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
WYKDG E+ + + R+KY E+ H + I+ T D G Y A N +V+ +
Sbjct: 3133 WYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLY------ 3186
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ A P+ L+P+ + G R AV+ P ++WY++ L +
Sbjct: 3187 --VNAPEPPQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL- 3242
Query: 3319 DRDGQ-IELALAAVTTRDAGVYTCTASNEVGRASTSGKV-----EVIGTDQTSEPRIPPV 3372
DGQ L L DA VYTC A N+ G A+TS + EV+ DQ P PP
Sbjct: 3243 -HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPA 3300
Query: 3373 VISP 3376
+I+P
Sbjct: 3301 IITP 3304
Score = 74.1 bits (174), Expect = 8e-12
Identities = 58/231 (25%), Positives = 97/231 (41%), Gaps = 24/231 (10%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PPT +++ + + LEC I G P P +TW+++D QI S +Q + G+ RL
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 954
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFV------NFTGRESQVSPNVVTAEKTRIARQ 2806
I EDSG +TC A N T + ++ F + V+ T EK + +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 2807 SL---------------ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
+ E P+F ++ GG++ ++ G P V W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 2851 SVTEVYRNARVFVEQ-GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+T YR + +Q G L +S ++G YT + HG +A++
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 74.1 bits (174), Expect = 8e-12
Identities = 60/229 (26%), Positives = 94/229 (41%), Gaps = 7/229 (3%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
ES S+ G P F+ + I G+ A L+ +V G P P + W NG +
Sbjct: 3440 ESPVYSTKFDSEKEGTGPIFIKEV-SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLT 3498
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
A F+G D L I ++DEG Y+C A+N +GK A L + + D
Sbjct: 3499 PSAD-YKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-NSKGEGHKDT 3556
Query: 3153 KLKRERSAEVE---GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVV 3209
+ + + +E G PP F L+ R P V+G P P V+W+K+ +++
Sbjct: 3557 ETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLC 3616
Query: 3210 YDKRRN-KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ T + +D G+Y A N G +C L+V
Sbjct: 3617 TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 73.3 bits (172), Expect = 1e-11
Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRK----PVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+S A S +S++ E+ T + ++ + F T + EG R+ L ++ ++D
Sbjct: 26513 KSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATD-- 26570
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
V W NGV L N +YR + TL + A D +C + + G + +L +
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL- 26629
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
S E S P ++ + +N ++ C I G+P P+I WFK++ I S +
Sbjct: 26630 -SKELSDAPAFISQPRSQNINEGQN-VLFTCEISGEPSPEIEWFKNNLPI-SISSNVSIS 26686
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ V L I N + DSG YT KA+N
Sbjct: 26687 RSRNVYSLEIRNASVSDSGKYTIKAKN 26713
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 71.7 bits (168), Expect = 4e-11
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 7/187 (3%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS-FD 3009
P P VVD + +SLAW K ++ Y +E + R V T N+ F
Sbjct: 22848 PSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR-VHTNATIRNTEFT 22906
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP--EFVDILPGQLKILAGET 3067
+LK G++Y FRV N G E S++ + I + P E D L + I AG +
Sbjct: 22907 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 22966
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L SV G+P P + W K G ++ A T++ L + +N D G+Y+ EA
Sbjct: 22967 LRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGKYTIEAE 23023
Query: 3128 NTHGKAS 3134
N GK S
Sbjct: 23024 NQSGKKS 23030
Score = 71.3 bits (167), Expect = 6e-11
Identities = 88/314 (28%), Positives = 138/314 (43%), Gaps = 31/314 (9%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAW--PKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
K K P PG+P V D N +++W PKSD +P+ Y +E E +WV
Sbjct: 11201 KHKFSPPSPPGKPVVTDITENAATVSWTLPKSD--GGSPITGYYMER----REVTGKWVR 11254
Query: 3000 LGITPLN--SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP 3057
+ TP+ F L +G Y FRV N G + S +S I +P I P
Sbjct: 11255 VNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPI-KACRPIKPPGPPINP 11313
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDINI 3116
+LK + ETA+L V KP+ G+ VE ++ G T+Q+N IN
Sbjct: 11314 -KLKDKSRETADL---VWTKPLSDGGSPILGYVVECQKPG--TAQWN---------RINK 11358
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+ R + + Y R + V E + + E + +PP+ + +
Sbjct: 11359 DELIRQCAFRVPGLIEGNEY-RFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTC 11417
Query: 3177 R---RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
R V+ +R+ +V G P P ++W K+G+ +V +KR + QD L+I
Sbjct: 11418 RDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA 11477
Query: 3234 DGGVYEVTARNNSG 3247
D G Y ++A+N+SG
Sbjct: 11478 DHGKYIISAKNSSG 11491
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 11/198 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N V+L W K + + Y VE + EG RW++ T + F
Sbjct: 15945 PGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKEL-PEG--RWMKASFTNIIDTHF 16001
Query: 3009 DAFNLKQGEEYHFRVTPRNRYG-WGESSQTSSSIGVGLAGDRPEFVDILP---GQLKILA 3064
+ L + Y FRV RN G + E S+++ +I D P + + P + + A
Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR-ISMDPKYKDTIVVHA 16060
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE+ + + GKP+P + W+K E+ A R+ + F L++KD D G Y
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTA-RLEIKSTDFATSLSVKDAVRVDSGNYIL 16119
Query: 3125 EATNTHGKASTYARLAVV 3142
+A N G+ S + V+
Sbjct: 16120 KAKNVAGERSVTVNVKVL 16137
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/202 (27%), Positives = 84/202 (41%), Gaps = 7/202 (3%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL- 3005
P PG P V D + VSL W + V+ Y +E + G RW++ T +
Sbjct: 22441 PVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 22500
Query: 3006 -NSFDAFNLKQGEEYHFRVTPRNRYG---WGESSQTSSSIGVGLAGDRPEFVDILPGQL- 3060
N F L +G+ Y FRV +N G G S + A + E L G L
Sbjct: 22501 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 22560
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
I AG L +V GKP P ++W K E+ + +++ Q+ G IK + D G
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSLQYTGKRATAVIKFCDRSDSG 22619
Query: 3121 RYSCEATNTHGKASTYARLAVV 3142
+Y+ N G + + V+
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVL 22641
Score = 71.3 bits (167), Expect = 6e-11
Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 17/198 (8%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
GE ++ P P V W K+G +++ + + T + + LTI + DD+ Y
Sbjct: 25207 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEY 25266
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
+ A N +G+ S A+L V D+ L+ P F L + Q
Sbjct: 25267 TVVARNKYGEDSCKAKLTVTLHPP--PTDSTLR------------PMFKRLLANAECQEG 25312
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK-YQDEQFHTLEIAPTNLDDGGVYEVT 3241
V +V G PPP + W KDG+ + ++ ++ L I T +D G Y VT
Sbjct: 25313 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25372
Query: 3242 ARNNSGAVSCHCGLVVDK 3259
A N +G+ SC L V++
Sbjct: 25373 ATNTAGSTSCQAHLQVER 25390
Score = 70.5 bits (165), Expect = 1e-10
Identities = 56/196 (28%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 2951 PGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS 3007
PGEP + D G +V L W + D +P L+Y VE L G++ R V G
Sbjct: 11604 PGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER-VHKGSIKETH 11662
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
+ + + Y FRV +N G + +T + V +P L G L + AG+T
Sbjct: 11663 YMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVV-VKEDLQKPVLDLKLSGVLTVKAGDT 11721
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
L V+GKP P V W K+ + + R+ ++ D G+Y A
Sbjct: 11722 IRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTA 11781
Query: 3127 TNTHGKASTYARLAVV 3142
TNT G YA + V+
Sbjct: 11782 TNTAGSFVAYATVNVL 11797
Score = 70.1 bits (164), Expect = 1e-10
Identities = 63/209 (30%), Positives = 85/209 (40%), Gaps = 12/209 (5%)
Query: 2941 PKP-KAV-PERIPGEPCV---VDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGA 2995
PKP KA+ P PG P VD VSL W K D +P+ Y VE EG
Sbjct: 10901 PKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE---YQEEGTQ 10957
Query: 2996 RWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS-SIGVGLAGDRPEF-V 3053
W++ L+QG+ Y FRV N G G T L E V
Sbjct: 10958 DWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDV 11017
Query: 3054 DILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
++ G L + AG T ++G PVP W +G E++ + T + + F LTIK+
Sbjct: 11018 KLIEG-LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKN 11075
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y +N G + L V+
Sbjct: 11076 CLRRDTGEYQITVSNAAGSKTVAVHLTVL 11104
Score = 70.1 bits (164), Expect = 1e-10
Identities = 80/324 (24%), Positives = 135/324 (41%), Gaps = 47/324 (14%)
Query: 2607 EGSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
EG VK C + + T VTWY L+N KY DG+ L V + D Y
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143
Query: 2666 CTVENENGAISTSANL------KVYPSFEASPI---------------PPTFTRSI-RDT 2703
C V N+ G S+ A L +VY + + PP FT + T
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 25203
Query: 2704 FHLAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLAD-GVCRLAIDNPTPED 2761
++ EN + I P P +TW+K ++I P D + + +D G+ +L I++ T +D
Sbjct: 25204 AYVGEN-VRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25262
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
YT A N G +S + VT + + RP F +L +
Sbjct: 25263 DAEYTVVARNKY------------GEDSCKAKLTVTLHPP----PTDSTLRPMFKRLLAN 25306
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTET 2878
+ G ++ ++ + G P ++W ++G+ ++ + N + + +GL Y L + D
Sbjct: 25307 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS-LGPNIEI-IHEGLDYYALHIRDTLPE 25364
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITV 2902
++G Y A + G+ A + V
Sbjct: 25365 DTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 70.1 bits (164), Expect = 1e-10
Identities = 57/238 (23%), Positives = 107/238 (44%), Gaps = 23/238 (9%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPL--PKITWFKDDKQIPSDGRYQAFYLADGV 2749
PP T+ ++ A E+ L C + L ++TW+KD K++ +G +Q Y ADG
Sbjct: 26220 PPKITQFLKAE---ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGT 26276
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQIT------HFVNFTGRESQVSPNVVTAEKT-- 2801
L I+N T D G Y C+ T + F + + S++S + +KT
Sbjct: 26277 YELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTE 26336
Query: 2802 -RIARQSLE------SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE-WLREGRSVT 2853
+ R++ S +P L D V+ V+ G P W ++G+++T
Sbjct: 26337 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26396
Query: 2854 EVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+ + ++ ++G + L + ++SGLYTC ++ G+V + +T+ D + +
Sbjct: 26397 QGGK-YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453
Score = 69.7 bits (163), Expect = 2e-10
Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 12/197 (6%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ +G+ A + G+P P + W K ++ + +G + L + + +D
Sbjct: 3204 VQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3262
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+CEA N +G A+T A L+V E + ++ V YPP L+D
Sbjct: 3263 YTCEAKNDYGVATTSASLSV-------EVPEVVSPDQEMPV---YPPAIITPLQDTVTSE 3312
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P R C+V G+ KVSWY +++ + Q E + LEIA +D G Y
Sbjct: 3313 GQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3371
Query: 3242 ARNNSGAVSCHCGLVVD 3258
A N G VS L ++
Sbjct: 3372 ASNAVGQVSSTANLSLE 3388
Score = 69.7 bits (163), Expect = 2e-10
Identities = 50/200 (25%), Positives = 89/200 (44%), Gaps = 10/200 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P + V D G +++AW + +P++ Y VE +G E +W+ + P+
Sbjct: 7787 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTE---KWMRVNSRPIK 7843
Query: 3007 SFDAFNLKQG----EEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI 3062
F +++G +EY RV N G E S+ S ++ V D +D+ + +
Sbjct: 7844 DL-KFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV-VAKDPDCKPTIDLETHDIIV 7901
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
+ GE ++ + PVP V W K+G EV + + R+T + + L + D G Y
Sbjct: 7902 IEGEKLSIPVPFRAVPVPTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIY 7960
Query: 3123 SCEATNTHGKASTYARLAVV 3142
+ N G A+ + V+
Sbjct: 7961 TITLENKLGSATASINVKVI 7980
Score = 69.7 bits (163), Expect = 2e-10
Identities = 61/210 (29%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP P P PG+P V + VSL W K A + Y VE + +G RW++
Sbjct: 19180 EPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERREL-PDG--RWLK 19236
Query: 3000 LGITPLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE----FV 3053
T + F+ L + + Y FRV RN S+ S S G + D E +
Sbjct: 19237 CNYTNIQETYFEVTELTEDQRYEFRVFARNAAD--SVSEPSESTGPIIVKDDVEPPRVMM 19294
Query: 3054 DI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
D+ + + AGE + + G+P+P + W K+G E+EE A R LT+K
Sbjct: 19295 DVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA-RTEIISTDNHTLLTVK 19353
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVV 3142
D D G+Y N G S V+
Sbjct: 19354 DCIRRDTGQYVLTLKNVAGTRSVAVNCKVL 19383
Score = 68.9 bits (161), Expect = 3e-10
Identities = 60/221 (27%), Positives = 87/221 (39%), Gaps = 28/221 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ GE+ L C + G P P V W + +++E + +G L I++ +D GR
Sbjct: 908 VIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI-ARLMIREAFAEDSGR 966
Query: 3122 YSCEATNTHGKASTYARLAV------------------------VTDRTVWEADAKLKRE 3157
++C A N G ST LAV V R V D L E
Sbjct: 967 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
++ E P T + + V+ V CQV G+P P V W K G + R
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGG-SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVS 1085
Query: 3218 QDEQFH--TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++Q L I+ T DD G Y + RN G S L+
Sbjct: 1086 YNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1126
Score = 68.9 bits (161), Expect = 3e-10
Identities = 54/191 (28%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 2945 AVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP 3004
A P PG+ + D SL W K + + VL Y VE G E +W + +
Sbjct: 17713 AEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE---KWSIVAESK 17769
Query: 3005 LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKIL 3063
+ + L G+EY FRV N G + + +P LP I
Sbjct: 17770 VCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLK--LPFNTYSIQ 17827
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AGE + V G+P P + W+K+G +++ R+ + L IK+ N DD G+Y+
Sbjct: 17828 AGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT-RVNVEETATSTVLHIKEGNKDDFGKYT 17886
Query: 3124 CEATNTHGKAS 3134
ATN+ G A+
Sbjct: 17887 VTATNSAGTAT 17897
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/195 (26%), Positives = 90/195 (46%), Gaps = 4/195 (2%)
Query: 2950 IPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFD 3009
+P + VVD + V+LAW K + + Y +E+ G E + V L T L
Sbjct: 23140 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-T 23198
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LKILAGET 3067
+L +GE+Y FR+ +N G E +T +++ V P + +P + + + AG
Sbjct: 23199 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23258
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L + G+P P W G ++ E+ R+T + + LTI++ I D G Y+ E
Sbjct: 23259 VELVIPIAGRPPPAASWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELK 23317
Query: 3128 NTHGKASTYARLAVV 3142
N G S ++ ++
Sbjct: 23318 NVTGTTSETIKVIIL 23332
Score = 68.1 bits (159), Expect = 5e-10
Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 13/191 (6%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P + N ++L W K + + Y VE + +G RW++ T + F
Sbjct: 17027 PGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDL-PDG--RWMKASFTNVIETQF 17083
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI-----LPGQLKIL 3063
L + + Y FRV +N G S+ S S G A D E I + +
Sbjct: 17084 TVSGLTEDQRYEFRVIAKNAAG--AISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17141
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
AGET L V GKP+P + W++ E+EE A R + F L +KD D G+Y
Sbjct: 17142 AGETFRLEADVHGKPLPTIEWLRGDKEIEESA-RCEIKNTDFKALLIVKDAIRIDGGQYI 17200
Query: 3124 CEATNTHGKAS 3134
A+N G S
Sbjct: 17201 LRASNVAGSKS 17211
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/175 (29%), Positives = 80/175 (45%), Gaps = 26/175 (14%)
Query: 3267 PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIEL 3326
P GL+ + + EG+ + + + YPS VTWYR+ ++ S +T + G L
Sbjct: 897 PTLVSGLKNVTVI-EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 954
Query: 3327 ALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ-------------TSEPRIPPV- 3372
+ D+G +TC+A NE G STS + V +++ T E R
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 3373 -VISPDVPYSKE---------PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ D ++E P FI KP + EG +V+ C+V G+PKP VYW
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Score = 67.7 bits (158), Expect = 7e-10
Identities = 59/210 (28%), Positives = 86/210 (40%), Gaps = 11/210 (5%)
Query: 2941 PKPKAVPERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW 2997
P+P E+ P P VVD + LAW K D + + Y +E + +G W
Sbjct: 22040 PEPIVATEQ-PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE---MRQKGSDFW 22095
Query: 2998 VELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP--EFVDI 3055
VE G T +F L + EY FRV +N G+ E + SS+ + P + I
Sbjct: 22096 VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGI 22155
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
+ AG + + G+P P V W + +E R++ LT+KD
Sbjct: 22156 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-KETDRVSITTTKDRTTLTVKDSM 22214
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDR 3145
D GRY NT G T++ VV R
Sbjct: 22215 RGDSGRYFLTLENTAG-VKTFSVTVVVIGR 22243
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/212 (24%), Positives = 88/212 (41%), Gaps = 21/212 (9%)
Query: 3066 ETANLTCSVKGKPVPG--VVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRY 3122
E A LTC V+ + V W K+G +++E G ++ L I ++ D+G Y
Sbjct: 26234 EIAKLTCVVESSVLRAKEVTWYKDGKKLKEN-GHFQFHYSADGTYELKINNLTESDQGEY 26292
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE-------------RSAEVEGDYP-- 3167
CE + G + T + +++ E +K+ R E + P
Sbjct: 26293 VCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPIS 26352
Query: 3168 --PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
P L+D V + + + G P P W KDG+ + + +D+ L
Sbjct: 26353 SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFL 26412
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
EI T+ D G+Y T +N++G+VS C L +
Sbjct: 26413 EIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Score = 67.3 bits (157), Expect = 9e-10
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 3202 YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI 3261
Y+DG ++Y K K D + ++ +D E+ + +C + K
Sbjct: 25122 YEDGVAILYVKDITKLDDGTYRC-KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIK 25180
Query: 3262 RAYVA-------PEFCCGLEPLYK--LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
R PEF PLY + G+ +R + +P VTWY+ G +++P
Sbjct: 25181 RRTDTMRLLERPPEFTL---PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25237
Query: 3313 R-AIMTLDRD-GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T + D G +L + +VTT D YT A N+ G S K+ V T P
Sbjct: 25238 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TLHP--- 25289
Query: 3371 PVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P + PMF R ++E +EG +V E V G P P + W +D
Sbjct: 25290 -----PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKD 25334
Score = 66.9 bits (156), Expect = 1e-09
Identities = 59/215 (27%), Positives = 96/215 (44%), Gaps = 12/215 (5%)
Query: 2931 INISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIG 2990
I + +T K VP+ PG+ V D N VSL+W K + + ++ Y VE +
Sbjct: 16618 IGLPAQTADPIKVAEVPQP-PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVE---MQ 16673
Query: 2991 AEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP 3050
A+ +W E NL QGEEY FRV N G S S ++ + +A D
Sbjct: 16674 AKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEK--GRSDPRSLAVPI-VAKDLV 16730
Query: 3051 EFVDILP--GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
D+ P + G+ + + G+P P + W K+G +++ R+ +
Sbjct: 16731 IEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTT-RINVTDSLDLTT 16789
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
L+IK+ + DD G+Y N G+ + A + +VT
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKT--ASIEIVT 16822
Score = 66.5 bits (155), Expect = 2e-09
Identities = 59/201 (29%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEG--GARW 2997
EP P PG+P ++ + V+L W K P+ T +K+ S+++ RW
Sbjct: 14852 EPMLALDPIDPPGKPVPLNITRHTVTLKWAK--PEYTG---GFKITSYIVEKRDLPNGRW 14906
Query: 2998 VELGITPL--NSFDAFNLKQGEEYHFRVTPRNRYGW-GESSQTSSSIGVGLAGDRPEF-V 3053
++ + + N F L + Y FRV +N G S+ S +I + P+ V
Sbjct: 14907 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV 14966
Query: 3054 DILPGQLKIL-AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
D+ IL AGE L V G+P P + W K+G E+E A ++ + F L K
Sbjct: 14967 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTA-KLEIKIADFSTNLVNK 15025
Query: 3113 DINIDDEGRYSCEATNTHGKA 3133
D D G Y+ ATN G A
Sbjct: 15026 DSTRRDSGAYTLTATNPGGFA 15046
Score = 66.5 bits (155), Expect = 2e-09
Identities = 57/199 (28%), Positives = 81/199 (40%), Gaps = 7/199 (3%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V D + VSLAW K APV Y VE A+
Sbjct: 18505 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGK 18564
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKIL-A 3064
F LK+ EY+FR+ N G GE + S+ + PE +D ++ +L A
Sbjct: 18565 QFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRA 18624
Query: 3065 GETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
T L ++KG+P P V W K G + +TS F L I ++ D GRY+
Sbjct: 18625 SATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFT----MLVIDNVTRFDSGRYN 18680
Query: 3124 CEATNTHGKASTYARLAVV 3142
N G + + + V+
Sbjct: 18681 LTLENNSGSKTAFVNVRVL 18699
Score = 66.1 bits (154), Expect = 2e-09
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G PT V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 65.7 bits (153), Expect = 3e-09
Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 10/209 (4%)
Query: 2940 EPKPKAVPERIPGEPCVV---DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR 2996
EP + P +P P V D N + L W + + Y VE G++ +
Sbjct: 7080 EPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD---K 7136
Query: 2997 WVELGITPLNS-FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE-FVD 3054
WV G + + L++G+ Y +RV NR G + S+ + I + PE F+D
Sbjct: 7137 WVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLD 7196
Query: 3055 I-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
+ L L + AG L +V GKP P + W K ++++ R+T + +TI D
Sbjct: 7197 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDK-RITIENVPKKSTVTIVD 7255
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y EA N G+A+ + V+
Sbjct: 7256 SKRSDTGTYIIEAVNVCGRATAVVEVNVL 7284
Score = 65.3 bits (152), Expect = 4e-09
Identities = 107/483 (22%), Positives = 196/483 (40%), Gaps = 51/483 (10%)
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
L + V G ++ L+ I G P+ V W RE + E + ++ + G+ L + +
Sbjct: 903 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSIDFQITFQSGIARLMIREAFA 961
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR---PEKDILIS---VGEDI 2931
+SG +TC A + G V + + V + + + + + EK + S V D
Sbjct: 962 EDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDT 1021
Query: 2932 NISFRTQGEPKPKA--------VPERIPGEPCVVD---GGNNWVSLAWPKSD-PQTTAPV 2979
+++ G +P A V + + G V GGN + W KS P TT
Sbjct: 1022 SLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-- 1079
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
YKV + G + + +T F GE + + RN++ GE+S ++S
Sbjct: 1080 YRYKVS---YNKQTGECKLVISMT-------FADDAGE---YTIVVRNKH--GETSASAS 1124
Query: 3040 SIGVGLAGDRPEFVDILPGQLKIL--AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
+ + ++ ++ Q ++L TA + G+ PG V+ + E E+E
Sbjct: 1125 LL------EEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQAL 1178
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ + D + ++D+ + K Y R+ T + E D + K
Sbjct: 1179 IRKKM-AKD--TVVVRTYVEDQEFHISSFEERLIKEIEY-RIIKTTLEELLEEDGEEKMA 1234
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNK 3216
F +R+++ R+ V C++ G P PK++WYKDG+ + + +R +
Sbjct: 1235 VDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1294
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
+ + +L I +D G+Y A N G C L V+ AP + LEP+
Sbjct: 1295 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPA-APLGAPTYIPTLEPV 1353
Query: 3277 YKL 3279
++
Sbjct: 1354 SRI 1356
Score = 65.3 bits (152), Expect = 4e-09
Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 6/189 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYR-KKLVDGLITL 2651
P F L + S L C V P V WYR G ++ + LKYR ++ G L
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ + D+ Y N+ G++S +A+L+V + +P T H E+
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGM--GAVHALRGEV 24547
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
V ++ G+P P ITW K I ++G YQ + + +D+G Y A+
Sbjct: 24548 VSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAK 24607
Query: 2771 NSVWTDQIT 2779
N DQ T
Sbjct: 24608 NRFGIDQKT 24616
Score = 64.5 bits (150), Expect = 6e-09
Identities = 31/95 (32%), Positives = 47/95 (49%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + L + T +EG V L C + PTVTWYR +++ + ++ G+ L +
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
A DS ++C+ NE G +STS L V S E
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 991
Score = 64.1 bits (149), Expect = 8e-09
Identities = 81/354 (22%), Positives = 136/354 (38%), Gaps = 42/354 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KPV T L D T S K PT W ++G + KY+ G LE
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL--KVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+ SDS Y+CTV+N G++S+S L K EA + T I E
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 26473
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+ + +R + + K++ K +++ L + ++ I + + T E
Sbjct: 26474 EISQKALRSEEI-KMSEAKSQEKLA---------LKEEASKVLISEEVKKSAAT---SLE 26520
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
S+ ++IT + SQ S V T + + T + G +
Sbjct: 26521 KSIVHEEIT-------KTSQASEEVRTHAEIKA--------------FSTQMSINEGQRL 26559
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ I G T V+W+ G +T R V TL + + + G+ TC + +
Sbjct: 26560 VLKANIAGA-TDVKWVLNGVELTN-SEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 26617
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
G V +T+ +L PA + +P I+ G+++ + GEP P+
Sbjct: 26618 EGIVKCQYDLTL--SKELSDAPA-FISQPRSQ-NINEGQNVLFTCEISGEPSPE 26667
Score = 63.7 bits (148), Expect = 1e-08
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 11/188 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
P +P +VD G +++AW K AP+ Y VE W + I L +
Sbjct: 19590 PSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVE---YKKSDDTDW-KTSIQSLRGTEY 19645
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAGE 3066
L G EY FRV N+ G + S +S + P F +D + L + AG
Sbjct: 19646 TISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGA 19705
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
+ +T +G+PVP V+W K ++ A T+ LTI++ N +D G+Y+
Sbjct: 19706 SFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR---TSLTIENANRNDSGKYTLTI 19762
Query: 3127 TNTHGKAS 3134
N AS
Sbjct: 19763 QNVLSAAS 19770
Score = 63.3 bits (147), Expect = 1e-08
Identities = 76/366 (20%), Positives = 142/366 (38%), Gaps = 53/366 (14%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ + A G+P P +W K+G + + S+ G L I + D G
Sbjct: 26366 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG-GFFLEIHKTDTSDSGL 26424
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADA-KLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
Y+C N+ G S+ +L + + + + +A K+ ++++E+ PQ +
Sbjct: 26425 YTCTVKNSAGSVSSSCKLTI---KAIKDTEAQKVSTQKTSEIT----PQ---------KK 26468
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
A ++ + + S K+S K E++ + +K + + A T+L+ V+E
Sbjct: 26469 AVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKKSAATSLEKSIVHEE 26527
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ + + I+A+ ++EG L + A + + V
Sbjct: 26528 ITKTSQASEEVR----THAEIKAFSTQ---------MSINEGQRLVLKANIAG--ATDVK 26572
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
W +GV L S + Q L + + RD G+ TC + + G
Sbjct: 26573 WVLNGVELTNSEEYRYGVSGSDQT-LTIKQASHRDEGILTCISKTKEGIVKCQ------- 26624
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
D T + S P FI +PRS EG V+ CE+ G+P P++ W ++
Sbjct: 26625 YDLTLSKEL-----------SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN 26673
Query: 3421 FLKVRI 3426
L + I
Sbjct: 26674 NLPISI 26679
Score = 62.5 bits (145), Expect = 3e-08
Identities = 53/192 (27%), Positives = 78/192 (40%), Gaps = 11/192 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V D + VSL+W K +P++ Y VE + WV + P N
Sbjct: 13091 PPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVE---VKRADSDNWVRCNL-PQN 13146
Query: 3007 ----SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG--LAGDRPEFVDILPGQL 3060
F+ L + +Y FRV N+ G+ + S L E L L
Sbjct: 13147 LQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTL 13206
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+ AG T L VKG+P P + W K + + G + + FD L +++N D G
Sbjct: 13207 ILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKSTDFDTFLRCENVNKYDAG 13265
Query: 3121 RYSCEATNTHGK 3132
+Y N+ GK
Sbjct: 13266 KYILTLENSCGK 13277
Score = 62.1 bits (144), Expect = 3e-08
Identities = 32/84 (38%), Positives = 42/84 (50%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E+ + F I++ L + C++ G PLPKI W+KD K+I RYQ +L D
Sbjct: 1239 ESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAEN 2771
G L I PED G YT A N
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASN 1322
Score = 62.1 bits (144), Expect = 3e-08
Identities = 58/205 (28%), Positives = 83/205 (40%), Gaps = 12/205 (5%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P + D L W K +P+L Y VE G A+W + L
Sbjct: 11306 PPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQ---KPGTAQWNRINKDELI 11362
Query: 3007 SFDAFN---LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LK 3061
AF L +G EY FR+ N G GE + + S+ PE +D+ +
Sbjct: 11363 RQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVIT 11422
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+ G+T + VKG+P P + W K G V E+ + + L IK+ D G
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE--LQIKEAVRADHG 11480
Query: 3121 RYSCEATNTHGKASTYARLAVVTDR 3145
+Y A N+ G A A + V DR
Sbjct: 11481 KYIISAKNSSGHAQGSA-IVNVLDR 11504
Score = 61.7 bits (143), Expect = 5e-08
Identities = 53/189 (28%), Positives = 81/189 (42%), Gaps = 8/189 (4%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQ 3015
V + N +LAW A + Y + S+ + RW E + S LK+
Sbjct: 12310 VTEMTKNSATLAWLPPLRDGGAKIDGY-ITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12368
Query: 3016 GEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDILPGQLKILAGETANLTCS 3073
G++Y FRV RN G S + GV A ++ P + ++P Q+ I AG+ +
Sbjct: 12369 GKKYKFRVAARNAVG---VSLPREAEGVYEAKEQLLPPKI-LMPEQITIKAGKKLRIEAH 12424
Query: 3074 VKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKA 3133
V GKP P W K EV + + + L IKD+ D G YS A N+ G
Sbjct: 12425 VYGKPHPTCKWKKGEDEVVTSSHLAVHKADS-SSILIIKDVTRKDSGYYSLTAENSSGTD 12483
Query: 3134 STYARLAVV 3142
+ ++ V+
Sbjct: 12484 TQKIKVVVM 12492
Score = 61.3 bits (142), Expect = 6e-08
Identities = 75/354 (21%), Positives = 141/354 (39%), Gaps = 23/354 (6%)
Query: 2571 KAFSEARSVISEKRTLSRNSTR--KPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTV 2625
K F E+R V+ +L+ +P F+T + VEG V C V + P V
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 2626 TWYRNGVLLDNKLKYRKKL--VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
W ++GV L +Y+ G L + D+ EY+ V N++G S SA+L
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1127
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA 2742
+E +S ++ + + V E ++ G+ P + + +K+ + QA
Sbjct: 1128 EADYE------LLMKSQQEMLYQTQVTAFVQEPKV-GETAPGFVYSEYEKEYEKE---QA 1177
Query: 2743 FYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
+ ED + E + +I + + T E + + EK
Sbjct: 1178 LIRKKMAKDTVVVRTYVEDQEFHISSFEERL-IKEIEYRIIKTTLEELLEED--GEEKMA 1234
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARV 2861
+ E+ F + +Y++ G + ++ G P ++ W ++G+ + R
Sbjct: 1235 VDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1294
Query: 2862 FVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVI 2915
F++ G +L + V + G+YT A + GN + + V+P+ G P I
Sbjct: 1295 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL-YVEPAAPLGAPTYI 1347
Score = 61.3 bits (142), Expect = 6e-08
Identities = 60/227 (26%), Positives = 93/227 (40%), Gaps = 16/227 (7%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+ T L D + EG V LT S+ ++ + V WY L+ + K++ TL +
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300
Query: 2654 LNAVPSD-SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENEL 2711
D EY C N++G +TSA L V A+P+ + HLA+
Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK--RAAPVIKRKIEPLEVALGHLAK--- 4355
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C I+ P + WFK ++I + + + + L I D G YTCKA N
Sbjct: 4356 -FTCEIQSAPNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKASN 4413
Query: 2772 SVWTDQITHFVNFT--GRESQVS---PNVVTAEKTRIARQSLESRRP 2813
+ T + T G E +V P K + +S+ +RP
Sbjct: 4414 EYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP 4460
Score = 61.3 bits (142), Expect = 6e-08
Identities = 58/216 (26%), Positives = 97/216 (44%), Gaps = 13/216 (6%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG-GVYEVTAR 3243
V LT + + +V+WY + + V D++ QD+ +TL I N +D G Y A
Sbjct: 4260 VHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 4317
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+SG + L V K RA AP +EPL ++ G + + +++ P+V W++
Sbjct: 4318 NDSGKTATSAKLTVVK--RA--APVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFK 4372
Query: 3304 DGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG--KVEVIG 3360
G + S + +I + +E+ V D G YTC ASNE G S + V V G
Sbjct: 4373 AGREIYESDKCSIRSSKYISSLEILRTQVV--DCGEYTCKASNEYGSVSCTATLTVTVPG 4430
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
++ +P P + + ++P E +
Sbjct: 4431 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPK 4466
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/204 (26%), Positives = 83/204 (40%), Gaps = 8/204 (3%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELG 3001
K A P P P V D SLAW K + Y VE +G E +
Sbjct: 14170 KDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGT 14229
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQ 3059
+ F +L+ E+Y+FR++ N G GE + + + P+F +D L
Sbjct: 14230 ALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA-VIPDVEIVEREMAPDFELDAELRRT 14288
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDD 3118
L + AG + + +KG+P P V W K+ ++ A T F L I + N D
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFT----LLIIPECNRYD 14344
Query: 3119 EGRYSCEATNTHGKASTYARLAVV 3142
G++ N GK S + + V+
Sbjct: 14345 TGKFVMTIENPAGKKSGFVNVRVL 14368
Score = 60.9 bits (141), Expect = 8e-08
Identities = 54/207 (26%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 2947 PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESW--LIGAEGGARWVELG 3001
P PG P VVD + ++L W K AP++ Y VE + A W
Sbjct: 11996 PIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCN 12055
Query: 3002 ITPL---NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPG 3058
F +L + +EY FRV +N+ G G ++ +I + PE +D+
Sbjct: 12056 AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPE-IDLDAS 12114
Query: 3059 QLKIL---AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
K++ AG L V+G+P P V W K G + G++ L I +
Sbjct: 12115 MRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQV--DLVDTMAFLVIPNST 12172
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVV 3142
DD G+YS N G+ + + + V+
Sbjct: 12173 RDDSGKYSLTLVNPAGEKAVFVNVRVL 12199
Score = 60.9 bits (141), Expect = 8e-08
Identities = 54/196 (27%), Positives = 85/196 (43%), Gaps = 9/196 (4%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGA-EGGARWVELGITPLNSFD 3009
P P V+D + V L+W K + Y VE + E GI N +
Sbjct: 16344 PNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN-IE 16402
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAGET 3067
L + EY+FR+ N+ G GE + I V + P+ +D+ L + I AG +
Sbjct: 16403 VEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGS 16462
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
L +KG+P P V W K E+ + A +TS F L + ++N D G+Y+
Sbjct: 16463 LRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTS----LVLDNVNRYDSGKYTLTL 16518
Query: 3127 TNTHGKASTYARLAVV 3142
N+ G S + + V+
Sbjct: 16519 ENSSGTKSAFVTVRVL 16534
Score = 60.9 bits (141), Expect = 8e-08
Identities = 76/311 (24%), Positives = 121/311 (38%), Gaps = 20/311 (6%)
Query: 2654 LNAVPSDSAEYSC--TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
LN V S +A SC + ++ G + A +KV S E P+ ++ + +
Sbjct: 25037 LNMVVS-AARISCGGAIRSQKGV--SVAKVKV-ASIEIGPVSGQIMHAVGEE----GGHV 25088
Query: 2712 VLECRIRG-QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
C+I ++TW+ +Q+ + +Y+ Y DGV L + + T D GTY CK
Sbjct: 25089 KYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYRCKVV 25147
Query: 2771 NSVWTDQITHFVNFTG-RE--SQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
N D + G RE + K R L R P F L + G
Sbjct: 25148 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25207
Query: 2828 GTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVE--QGLYTLALSDVTETESGLYT 2884
+ V I P V W + G+ + + + E +GLY L ++ VT + YT
Sbjct: 25208 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 25267
Query: 2885 CRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
A + +G A +TV + P D + R + G+ + R G P P
Sbjct: 25268 VVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPP 25327
Query: 2944 KAVPERIPGEP 2954
E+ G+P
Sbjct: 25328 TLKWEK-DGQP 25337
Score = 60.5 bits (140), Expect = 1e-07
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 15/173 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D T G C +S D V WY G L+ K + + TL + +
Sbjct: 5705 LKDVTVTAGETATFDCE-LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 5763
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ E T ++ T ANL F P P FT+ + D VLEC +
Sbjct: 5764 DAGEVQLTAKD----FKTHANL-----FVKEP-PVEFTKPLEDQTVEEGATAVLECEVSR 5813
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAEN 2771
+ K+ WFK+ +I +Y+ +ADG V +L I + TPED TYTC A++
Sbjct: 5814 ENA-KVKWFKNGTEILKSKKYEI--VADGRVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 60.5 bits (140), Expect = 1e-07
Identities = 51/187 (27%), Positives = 83/187 (44%), Gaps = 19/187 (10%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVL 2654
F+ L D+T EG+ L C V S + V W++NG + KY + + DG + L +
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKY-EIVADGRVRKLVIH 5847
Query: 2655 NAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-L 2713
+ P D Y+C ++ TS NL V P F R + D + E E+
Sbjct: 5848 DCTPEDIKTYTCDAKD----FKTSCNLNVVPPH------VEFLRPLTD-LQVREKEMARF 5896
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENS 2772
EC + + K+ WFKD +I +Y ++ G R L I+ +D Y+C+ +
Sbjct: 5897 ECEL-SRENAKVKWFKDGAEIKKGKKYD--IISKGAVRILVINKCLLDDEAEYSCEVRTA 5953
Query: 2773 VWTDQIT 2779
+ +T
Sbjct: 5954 RTSGMLT 5960
Score = 60.5 bits (140), Expect = 1e-07
Identities = 51/175 (29%), Positives = 81/175 (46%), Gaps = 17/175 (9%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN-AVP 2658
LTD E + C +S + V W+++G + KY + G + + V+N +
Sbjct: 5883 LTDLQVREKEMARFECE-LSRENAKVKWFKDGAEIKKGKKY-DIISKGAVRILVINKCLL 5940
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D AEYSC V TS L V EA FT+++ + + + L C +
Sbjct: 5941 DDEAEYSCEVRTAR----TSGMLTVLEE-EA-----VFTKNLANIEVSETDTIKLVCEV- 5989
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAENS 2772
+P ++ W+K D++I GRY+ L +G R L I N ED+G Y C+ +S
Sbjct: 5990 SKPGAEVIWYKGDEEIIETGRYE--ILTEGRKRILVIQNAHLEDAGNYNCRLPSS 6042
Score = 60.5 bits (140), Expect = 1e-07
Identities = 54/193 (27%), Positives = 81/193 (41%), Gaps = 9/193 (4%)
Query: 2947 PERIPGEPCVV---DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P PG P VV D VSL W K ++ Y +E G V
Sbjct: 21753 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADL-GDWHKVNAEAC 21811
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKI 3062
+ +L+ GEEY FRV+ N G G+S + + +I PE +D Q +
Sbjct: 21812 VKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHV 21871
Query: 3063 L-AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AG + L + +G+P P VW K + A T+ + F LT+++ N +D G+
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT--DSFS-TLTVENCNRNDAGK 21928
Query: 3122 YSCEATNTHGKAS 3134
Y+ N G S
Sbjct: 21929 YTLTVENNSGSKS 21941
Score = 60.1 bits (139), Expect = 1e-07
Identities = 62/263 (23%), Positives = 104/263 (39%), Gaps = 17/263 (6%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG P V+D + +S+AW K + + Y VE L + S+
Sbjct: 15262 PGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTI 15321
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEFVDI---LPGQLKILAG 3065
L + +EY R+ N G GE + G A DR P +++ L + I A
Sbjct: 15322 TGLTENQEYKIRIYAMNSEGLGEPALVP---GTPKAEDRMLPPEIELDADLRKVVTIRAC 15378
Query: 3066 ETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
T L +KG+P P V W + +G +++ + TS + L + ++N D G+Y
Sbjct: 15379 CTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYT----LLIVGNVNRFDSGKYIL 15434
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFT---MRLRDRRVQA 3181
N+ G S + + V+ D D K+K V + P ++++ V+
Sbjct: 15435 TVENSSGSKSAFVNVRVL-DTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEK 15493
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKD 3204
R + + K SW D
Sbjct: 15494 RESTRKAYSTVATNCHKTSWKVD 15516
Score = 60.1 bits (139), Expect = 1e-07
Identities = 43/157 (27%), Positives = 69/157 (43%), Gaps = 8/157 (5%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
R+ +S K L+ S P + D T G +L+C ++ P + WYR G L
Sbjct: 24021 RTAMSIKTKLT--SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 24078
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
KY+ TL V+ D Y+C NE G + TS+ L + + + P P
Sbjct: 24079 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP-- 24136
Query: 2697 TRSIRDTFHLA-ENELVLECRIRGQPLPKITWFKDDK 2732
+++ ++ A + L L G+P+P +TWF K
Sbjct: 24137 ---LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK 24170
Score = 59.3 bits (137), Expect = 2e-07
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 18/149 (12%)
Query: 3273 LEPL-YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P+ +K EG R V P W+ DG ++ + + DG L +
Sbjct: 1415 LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPA 1474
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
T D+G +T A N GR+S + VI T + E ++ +PMF+ K +
Sbjct: 1475 TPSDSGEWTVVAQNRAGRSS----ISVILTVEAVEHQV-------------KPMFVEKLK 1517
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ +EG + ++ G+P PD+ WL++
Sbjct: 1518 NVNIKEGSQLEMKVRATGNPNPDIVWLKN 1546
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/277 (24%), Positives = 115/277 (41%), Gaps = 32/277 (11%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRYS 3123
G A+ V GKP P W KNG ++E + R+ + + C L I+D+ +D
Sbjct: 2046 GSDAHFRVRVVGKPDPECEWYKNGVKIER-SDRIYWYWPEDNVCELVIRDVTAEDSASIM 2104
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
+A N G+ S++A L V AK + E++ + +++ AT+
Sbjct: 2105 VKAINIAGETSSHAFLLV---------QAKQLITFTQELQD-------VVAKEKDTMATF 2148
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C+ P KV WYKDG EV + + D + H L I + D Y
Sbjct: 2149 E----CET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+ V L+V+ + EF L+ + ++ E + +V ++ WY
Sbjct: 2204 EDEN-VKTTAKLIVEGAV-----VEFVKELQDI-EVPESYSGELECIVSP-ENIEGKWYH 2255
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
+ V L+ + + +T R G+ L + VT D G Y+
Sbjct: 2256 NDVELKSNGKYTIT-SRRGRQNLTVKDVTKEDQGEYS 2291
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 22/150 (14%)
Query: 3109 LTIKDINIDD-EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I +N +D +G Y CEA N GK +T A+L VV +R+A
Sbjct: 4298 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV--------------KRAA------- 4336
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P ++ V + + TC++ +P + W+K G E+ + + + +LEI
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
T + D G Y A N G+VSC L V
Sbjct: 4397 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 58.8 bits (136), Expect = 3e-07
Identities = 55/208 (26%), Positives = 92/208 (44%), Gaps = 8/208 (3%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP P PG+P V++ N V+L W + + Y VE + ++ +
Sbjct: 13769 EPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANH 13828
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGW-GESSQTSSSIGVGLAGDRPEFV--DIL 3056
+ + P +F +L +G +Y FR+ +N G S+++ +I + P V +
Sbjct: 13829 VNV-PECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTI 13887
Query: 3057 PGQLKILAGETANLTC-SVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCCLTIKDI 3114
L I AG+T L S+ GKP+P W K G ++ + ++TS LTIK
Sbjct: 13888 KDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITS--TPTSSMLTIKYA 13945
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVV 3142
D G Y+ ATN G + ++ V+
Sbjct: 13946 TRKDAGEYTITATNPFGTKVEHVKVTVL 13973
Score = 58.4 bits (135), Expect = 4e-07
Identities = 54/216 (25%), Positives = 92/216 (42%), Gaps = 16/216 (7%)
Query: 2939 GEPKPKAV------PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLI 2989
GEP P V P PG P +VD N ++LAW K + +L Y VE
Sbjct: 17405 GEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA 17464
Query: 2990 GAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR 3049
E + F+ L + +EY RV N+ G GE++ ++ +
Sbjct: 17465 DEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEA 17524
Query: 3050 PEFVDI---LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
PE +D+ L + + AG +A + KG+P P + W + E ++ ++ N
Sbjct: 17525 PE-LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKV-QIEKGVNYTQ 17582
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L+I + + +D G+Y + N+ G S + + V+
Sbjct: 17583 --LSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVL 17616
Score = 58.0 bits (134), Expect = 6e-07
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 58.0 bits (134), Expect = 6e-07
Identities = 51/206 (24%), Positives = 82/206 (39%), Gaps = 6/206 (2%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP + P PG +VD N ++ W K + + + Y VE + +G +W
Sbjct: 18791 EPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVE---MQTKGSEKWST 18847
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
L GEEY FRV N G + Q + +P V++
Sbjct: 18848 CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS-VELPFHT 18906
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+ A E + KG+P V W K+G ++E R+ + L+IK+ + +D
Sbjct: 18907 FNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETT-RVNVSSSKTVTSLSIKEASKEDV 18965
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDR 3145
G Y +N+ G + T +V DR
Sbjct: 18966 GTYELCVSNSAG-SITVPITIIVLDR 18990
Score = 58.0 bits (134), Expect = 6e-07
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 7/184 (3%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRV 3023
VSL W K + + ++ Y VE+ +G WV+ + L++ EY FRV
Sbjct: 19894 VSLTWLKPEHDGGSRIVHYVVEAL---EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRV 19950
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LKILAGETANLTCSVKGKPVPG 3081
N+ G + + + + + PE + P + + AG + + GKP+P
Sbjct: 19951 FAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPK 20010
Query: 3082 VVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
V ++G ++ R ++ + + +K+ D GRY A N+ G + + V
Sbjct: 20011 VTLSRDGVPLKATM-RFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINI-V 20068
Query: 3142 VTDR 3145
V DR
Sbjct: 20069 VLDR 20072
Score = 57.2 bits (132), Expect = 1e-06
Identities = 90/397 (22%), Positives = 152/397 (38%), Gaps = 56/397 (14%)
Query: 3076 GKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAS 3134
G P V W+ +G +E RM ++F G+ C L D G +C ATN +G
Sbjct: 1684 GDPTMVVEWLHDGKPLEAANRLRMINEF-GY-CSLDYGVAYSRDSGIITCRATNKYGTDH 1741
Query: 3135 TYARLAVVTDRTVWEA----DAKLKRERSAEVEG----------------DYPPQFTMRL 3174
T A L V ++++ E + + +R E+E P +
Sbjct: 1742 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1801
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
RV R C+V G P PKV+WY +G +++ +R + + + H L+I D
Sbjct: 1802 EPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIHYLDIVDCKSYD 1860
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD--KGIRAYV--APEFCCGLEPLYKLHEGDELRISAV 3290
G +VTA N G + L + + R+ + APE P + +HE +L+ V
Sbjct: 1861 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPE----PRPEFHVHEPGKLQFE-V 1915
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV-GR 3349
+ V T ++ V+L+ + R + EL + G Y + E+ R
Sbjct: 1916 QKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSR 1975
Query: 3350 ASTSGKVEVIG-------------TDQ-----TSEPRIPPVVISPD----VPYSKEPMFI 3387
E++ T++ E +I PD P + P
Sbjct: 1976 KKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF 2035
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+ +S +G VVG P P+ W ++ +K+
Sbjct: 2036 ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2072
Score = 57.2 bits (132), Expect = 1e-06
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 3/201 (1%)
Query: 2942 KPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELG 3001
+P VPER P + V + N V+L W + ++ Y +ES LIG E +
Sbjct: 10215 EPITVPER-PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10273
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLK 3061
+ + LK+G+ Y +RV+ N G G+ S + I P +L
Sbjct: 10274 LLS-RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLT 10332
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GE LT GKP P V W K+ +V E+ R + L D G+
Sbjct: 10333 IRVGEAFALTGRYSGKPKPKVSWFKDEADVLED-DRTHIKTTPATLALEKIKAKRSDSGK 10391
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y N+ G + ++ VV
Sbjct: 10392 YCVVVENSTGSRKGFCQVNVV 10412
Score = 56.8 bits (131), Expect = 1e-06
Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD +S V P + W+ +GV L PS D D L + D G YTC
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTC 3529
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM---FIRKPRSSEAREG 3398
ASN+ G+ S +++ + + ++ + P F+++ + +G
Sbjct: 3530 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3589
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
I E VVG+P P V W ++
Sbjct: 3590 LPAIFEYTVVGEPAPTVTWFKE 3611
Score = 56.8 bits (131), Expect = 1e-06
Identities = 52/192 (27%), Positives = 78/192 (40%), Gaps = 8/192 (4%)
Query: 2951 PGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS 3007
PG P + D + ++L W K + V Y VE E G
Sbjct: 20670 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTE 20729
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLKILAG 3065
+ NLK G Y+FRV+ N G GE + + + + PE +D+ L + AG
Sbjct: 20730 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20789
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
E + KG+P P V W K+ + +A R + + LTI + +D G+Y
Sbjct: 20790 EDVQVLIPFKGRPPPTVTWRKDEKNLGSDA-RYSIENTDSSSLLTIPQVTRNDTGKYILT 20848
Query: 3126 ATNTHG--KAST 3135
N G K+ST
Sbjct: 20849 IENGVGEPKSST 20860
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/199 (24%), Positives = 79/199 (39%), Gaps = 22/199 (11%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
Q+ I G+ L ++ G V W+ NG E+ +G D LTIK + D
Sbjct: 26550 QMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSE-EYRYGVSGSDQTLTIKQASHRD 26606
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
EG +C + G + D L +E S P F + R +
Sbjct: 26607 EGILTCISKTKEGIVKC-------------QYDLTLSKELSDA------PAFISQPRSQN 26647
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ V TC++ G P P++ W+K+ + + + ++LEI ++ D G Y
Sbjct: 26648 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 26707
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
+ A+N G S L+V
Sbjct: 26708 TIKAKNFRGQCSATASLMV 26726
Score = 56.4 bits (130), Expect = 2e-06
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 11/178 (6%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVLNAVPSDSA 2662
T V+G + L+C + D V W ++G ++ K V GL+ L + +A +D+
Sbjct: 4726 TVVKGQPLYLSCELNKERD--VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAG 4783
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+ TVEN N + S+ +KV I + IRD + + C I +
Sbjct: 4784 TYTVTVENANN-LECSSCVKV-----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDT 4836
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P I WFK +IP++ + L DG L I N PED Y + E + ++T
Sbjct: 4837 PNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLT 4894
Score = 56.4 bits (130), Expect = 2e-06
Identities = 62/312 (19%), Positives = 122/312 (39%), Gaps = 24/312 (7%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
D P F+ P I G+ TC + G+P P + W KN + + S+
Sbjct: 26635 DAPAFIS-QPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV-Y 26692
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I++ ++ D G+Y+ +A N G+ S A L V+ + L+ ++G +
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 26752
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
Q ++++ + +A++ S + + + E F +E+
Sbjct: 26753 SQ-SVQMSASKQEASFS--------SFSSSSASSMTEMKFASMSAQSMSSMQESF--VEM 26801
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+ ++ G+ +T +S + G+ +GI P L + EG L +
Sbjct: 26802 SSSSF--MGISNMTQLESSTSKMLKAGI---RGI-----PPKIEALPSDISIDEGKVLTV 26851
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR-DGQIELALAAVTTRDAGVYTCTASNE 3346
+ P+ VTW G ++ + ++ D L + V +D G+YT + NE
Sbjct: 26852 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 26911
Query: 3347 VGRASTSGKVEV 3358
G S + + +
Sbjct: 26912 FGSDSATVNIHI 26923
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 8/194 (4%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDEQFHTLE 3226
P+ R++ + V +V+G P P+ WYK+G ++ R Y ++ L
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I +D V A N +G S H L+V +A F L+ + E D +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQLITFTQELQDVV-AKEKDTMA 2146
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ P V V WY+DG+ + + M DR L++ + T DA Y+C E
Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHF-LSILTIDTSDAEDYSCVLV-E 2204
Query: 3347 VGRASTSGKVEVIG 3360
T+ K+ V G
Sbjct: 2205 DENVKTTAKLIVEG 2218
Score = 56.0 bits (129), Expect = 2e-06
Identities = 57/212 (26%), Positives = 88/212 (41%), Gaps = 22/212 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP-- 3004
P P P V D + +SL W +P+ Y VE + EG W +
Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVE---MQEEGTTDWKRVNEPDKL 9263
Query: 3005 LNSFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE-FVDI-LPGQL 3060
+ + + NLK+ +Y FRV N G E S T+ I + PE F+DI L
Sbjct: 9264 ITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCL 9323
Query: 3061 KILAGETANLTCSVKGKPVPGVVW---------MKNG-HEVEEEAGRMTSQFNGFDCCLT 3110
AG + +KG+P P W MK+G H++ E+A T++ + +
Sbjct: 9324 VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS---VII 9380
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I + G+YS A N G+ + R+ V+
Sbjct: 9381 IPECKRSHTGKYSITAKNKAGQKTANCRVKVM 9412
Score = 55.6 bits (128), Expect = 3e-06
Identities = 53/207 (25%), Positives = 86/207 (41%), Gaps = 13/207 (6%)
Query: 2940 EPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
EP + P ++D + VSLAWPK + + Y +E+ +G +W
Sbjct: 14460 EPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEA---QRKGSDQWTH 14516
Query: 3000 LGITPLNSFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP 3057
IT + + NL +GEEY F+V N G + + S + V PE +D+
Sbjct: 14517 --ITTVKGLECVVRNLTEGEEYTFQVMAVNSAG-RSAPRESRPVIVKEQTMLPE-LDLRG 14572
Query: 3058 GQLKIL---AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
K++ AG+ + V G+P P V W K G ++ ++ R+ + L I +
Sbjct: 14573 IYQKLVIAKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINEC 14631
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAV 3141
D G Y A N G+ + V
Sbjct: 14632 VRSDSGPYPLTARNIVGEVGDVITIQV 14658
Score = 55.2 bits (127), Expect = 4e-06
Identities = 29/90 (32%), Positives = 43/90 (47%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P + +QA +++ VIG P P +SW KDGE + R N + L I
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
N DD G Y VTA N++G + + ++V
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 55.2 bits (127), Expect = 4e-06
Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
TLS+ + P F + + EG V TC + P + W++N + +
Sbjct: 26628 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 26687
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT 2703
+ +LE+ NA SDS +Y+ +N G S +A+L V P E P R+ DT
Sbjct: 26688 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE-EPSREVVLRTSGDT 26745
Score = 54.8 bits (126), Expect = 5e-06
Identities = 50/230 (21%), Positives = 86/230 (37%), Gaps = 5/230 (2%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P F + + + + L + G P PKI WF + + Y+ + D +
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
+ ED G YTC A N + ++ + + + + P
Sbjct: 3517 LFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3575
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLA 2871
HF L + A+G + + G P V W +E + + T VY + G T
Sbjct: 3576 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTI-IHNPNGSGTFI 3634
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPE 2920
++D +SGLY C+A + G A + V ++ +D+ P PE
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPE 3684
Score = 54.8 bits (126), Expect = 5e-06
Identities = 61/256 (23%), Positives = 99/256 (38%), Gaps = 25/256 (9%)
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAG 3065
NS+ L++G Y+FRVT N YG G +QT+ I V P + + ++
Sbjct: 16593 NSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSL 16652
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
K + +V M+ H E E R+ S I ++ +E +
Sbjct: 16653 SWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKS------LQAVITNLTQGEEYLFRV 16706
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G++ + + + + +E D P F+ VQ
Sbjct: 16707 VAVNEKGRSDPRSLAVPIVAKDL-------------VIEPDVKPAFS----SYSVQVGQD 16749
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+++ + G P P ++W KDG + R N TL I T+ DDGG Y +T N
Sbjct: 16750 LKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVAN 16809
Query: 3245 NSGAVSCHCGLV-VDK 3259
G + +V +DK
Sbjct: 16810 VVGQKTASIEIVTLDK 16825
Score = 54.4 bits (125), Expect = 7e-06
Identities = 54/214 (25%), Positives = 90/214 (42%), Gaps = 25/214 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDC 3107
+P FV + P K L G+TA V G+P+P W +G + V + ++ + +G
Sbjct: 1410 KPVFV-LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ- 1467
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I D G ++ A N G++S L V EA VE
Sbjct: 1468 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV-------EA-----------VEHQVK 1509
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVV---YDKRRNKYQDEQFHT 3224
P F +L++ ++ + + + G+P P + W K+ + +V Y K R + +
Sbjct: 1510 PMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE-AA 1568
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
L+I T D Y TA N +G + C + V+
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 54.4 bits (125), Expect = 7e-06
Identities = 47/141 (33%), Positives = 65/141 (46%), Gaps = 14/141 (9%)
Query: 3230 TNLDDGGVYE--VTARNNSGAVSC---HCGLVV--DKGIRAYV--APEFCCGLEPLYKLH 3280
T L G YE + ARN G +S G+++ D+ + V PE+ GL +
Sbjct: 21419 TGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLI----IK 21474
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
G+ LRI A+V+ P VTW++DGV + R + D G L + T GVYT
Sbjct: 21475 SGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNMEITDVLGSTSLFVRDATRDHRGVYT 21533
Query: 3341 CTASNEVGRASTSGKVEVIGT 3361
A N G A KV+V T
Sbjct: 21534 VEAKNASGSAKAEIKVKVQDT 21554
Score = 54.4 bits (125), Expect = 7e-06
Identities = 32/128 (25%), Positives = 51/128 (39%), Gaps = 1/128 (0%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + + GE+A +C G+PVP V W++ G +V + R + I +
Sbjct: 26070 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKG-QVLSTSARHQVTTTKYKSTFEISSVQA 26128
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DEG YS N+ GK L + R +A R +S E P R
Sbjct: 26129 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRV 26188
Query: 3177 RRVQATYP 3184
+ + ++P
Sbjct: 26189 KSPEPSHP 26196
Score = 53.6 bits (123), Expect = 1e-05
Identities = 56/229 (24%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+E EG P F + + + L+ VIG P PK+ W+ +G + D
Sbjct: 3450 SEKEGT-GPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 3508
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--------DKGIRAYVA----- 3266
H+L I T L+D G Y A N+ G C L + D + VA
Sbjct: 3509 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3568
Query: 3267 ------PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR 3320
P F L+P+ + +G V P+ VTW+++ +L S + +
Sbjct: 3569 LGGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 3627
Query: 3321 DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI--GTDQTSEP 3367
+G + D+G+Y C A N +G ++ + ++ V+ TD T P
Sbjct: 3628 NGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3676
Score = 53.6 bits (123), Expect = 1e-05
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 6/151 (3%)
Query: 2947 PERIPGEPCVVDGGN---NWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P++ P P V+ N +++ W + ++ Y +E G E R E +
Sbjct: 8079 PKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNE-HLV 8137
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL 3063
P+ ++ A L++G+EY FRV N G E S+ + D P+ IL L++
Sbjct: 8138 PILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV--ILRTSLEVK 8195
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
G+ L S+ G P P + W+K+ + + E
Sbjct: 8196 RGDEIALDASISGSPYPTITWIKDENVIVPE 8226
Score = 53.6 bits (123), Expect = 1e-05
Identities = 50/195 (25%), Positives = 78/195 (40%), Gaps = 6/195 (3%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT-PLNSFD 3009
P P +D N V L W + +L Y VE +G E R + P +
Sbjct: 10619 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10678
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFV-DI-LPGQLKILAGET 3067
L+ G+ Y FRV N G + + + V + PE + D + + I G+T
Sbjct: 10679 VTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDT 10738
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L+ +KG P P V W K + +A R+ G L I++ +D G YS
Sbjct: 10739 LRLSAIIKGVPFPKVTWKKEDRDAPTKA-RIDVTPVGSK--LEIRNAAHEDGGIYSLTVE 10795
Query: 3128 NTHGKASTYARLAVV 3142
N G + ++ V+
Sbjct: 10796 NPAGSKTVSVKVLVL 10810
Score = 53.6 bits (123), Expect = 1e-05
Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 11/170 (6%)
Query: 2958 DGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGE 3017
D V L+W K D + + Y VE +G W GI+ + LK+
Sbjct: 20976 DSTKTSVILSWTKPDFDGGSVITEYVVER---KGKGEQTWSHAGISKTCEIEVSQLKEQS 21032
Query: 3018 EYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDI--LPG-QLKILAGETANLTCSV 3074
FRV +N G + T I V PE VD+ +PG Q+ + G +L
Sbjct: 21033 VLEFRVFAKNEKGLSDPV-TIGPITVKELIITPE-VDLSDIPGAQVTVRIGHNVHLELPY 21090
Query: 3075 KGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
KGKP P + W+K+G ++E E R + N L+IK+ + G+Y+
Sbjct: 21091 KGKPKPSISWLKDGLPLKESEFVRFSKTEN--KITLSIKNAKKEHGGKYT 21138
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/96 (30%), Positives = 40/96 (41%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
D+ P+ T+R+R RV R V P +V WY +G E+ + + T
Sbjct: 25874 DHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKG 3260
LEI + DD G Y N G S + L V G
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGG 25969
Score = 52.8 bits (121), Expect = 2e-05
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query: 2568 HRSKAFSEARSVISEKRTLSRNSTRKPVFSTF----LT---DRTAVEGSRVKLTCSVISS 2620
+ A +E +S E+++L ST + + +T LT T EG + +C
Sbjct: 26031 YEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGE 26090
Query: 2621 SDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENG 2673
PTVTW R G +L +++ T E+ + SD YS VEN G
Sbjct: 26091 PVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 26143
Score = 52.4 bits (120), Expect = 3e-05
Identities = 52/183 (28%), Positives = 80/183 (43%), Gaps = 15/183 (8%)
Query: 2965 SLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVT 3024
S+ W K + ++ Y V+ + E +W + + + A +L +G+EY FRV+
Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVD--FLTEEN--KWQRVMKSLSLQYSAKDLTEGKEYTFRVS 13459
Query: 3025 PRNRYGWGESSQTSSSIGVGLAGDRPEFVDI-LPG--QLKILAGETAN--LTCSVKGKPV 3079
N G G T S I V +A D D+ L G L LA E +N L +KGKP
Sbjct: 13460 AENENGEG----TPSEITV-VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13514
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
P V W K G + R++ + + + L + D D G+Y+ N G +
Sbjct: 13515 PSVSW-KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISI 13573
Query: 3140 AVV 3142
VV
Sbjct: 13574 KVV 13576
Score = 52.4 bits (120), Expect = 3e-05
Identities = 54/199 (27%), Positives = 83/199 (41%), Gaps = 23/199 (11%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--FDAFNL 3013
+ D N VSL+W + + + Y VE + +G RW + T + F L
Sbjct: 20279 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDL-PDG--RWTKASFTNVTETQFIISGL 20335
Query: 3014 KQGEEYHFRVTPRNRYGWGESSQTSSSIGV--------GLAGDRP-EFVDILPGQLKILA 3064
Q +Y FRV RN G S S +G G D P E+ +++ K A
Sbjct: 20336 TQNSQYEFRVFARNAVG--SISNPSEVVGPITCIDSYGGPVIDLPLEYTEVV----KYRA 20389
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD-CCLTIKDINIDDEGRYS 3123
G + L + GKP P + W K+ E++ A + N D + IKD + + G Y
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNA--LVCVENTTDLASILIKDADRLNSGCYE 20447
Query: 3124 CEATNTHGKASTYARLAVV 3142
+ N G AS R+ ++
Sbjct: 20448 LKLRNAMGSASATIRVQIL 20466
Score = 52.0 bits (119), Expect = 4e-05
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
EG++L I A P V+W++DG ++ S R M D L + DAG+YT
Sbjct: 7903 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISA-HLEVPKSVRADAGIYT 7961
Query: 3341 CTASNEVGRASTSGKVEVIG 3360
T N++G A+ S V+VIG
Sbjct: 7962 ITLENKLGSATASINVKVIG 7981
Score = 51.6 bits (118), Expect = 5e-05
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK-Y 2640
+K LS + +F + +T +GS V+ DP WY+NGV ++ + Y
Sbjct: 2021 DKIELSPSMEAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSI 2700
D + L + + DSA N G S+ A L V +A + TFT+ +
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQL-ITFTQEL 2134
Query: 2701 RDTFHLAENEL-VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+D ++ + EC +P K+ W+KD ++ +Y+ + V L+I
Sbjct: 2135 QDVVAKEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSDRKVHFLSILTIDT 2192
Query: 2760 EDSGTYTC 2767
D+ Y+C
Sbjct: 2193 SDAEDYSC 2200
Score = 51.2 bits (117), Expect = 6e-05
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T + +KP + +EG + C V P V WY NG L+ ++R +
Sbjct: 1786 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR- 1844
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
DG+ L++++ D+ E T EN G I L++
Sbjct: 1845 YDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 50.8 bits (116), Expect = 8e-05
Identities = 78/344 (22%), Positives = 137/344 (39%), Gaps = 47/344 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AGETA C + + +P V W G ++E + ++ + G LT++D+ ++D G
Sbjct: 5710 VTAGETATFDCELSYEDIP-VEWYLKGKKLEP-SDKVVPRSEGKVHTLTLRDVKLEDAG- 5766
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
E T T+A L V + P +FT L D+ V+
Sbjct: 5767 ---EVQLTAKDFKTHANLFV----------------------KEPPVEFTKPLEDQTVEE 5801
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
L C+V KV W+K+G E++ K+ D + L I +D Y
Sbjct: 5802 GATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCD 5860
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
A++ SC+ +V EF L L ++ E + R + + + V W
Sbjct: 5861 AKDFK--TSCNLNVVPPH-------VEFLRPLTDL-QVREKEMARFECEL-SRENAKVKW 5909
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++DG ++ ++ + + + L + D Y+C EV A TSG + V+
Sbjct: 5910 FKDGAEIKKGKKYDI-ISKGAVRILVINKCLLDDEAEYSC----EVRTARTSGMLTVLEE 5964
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA-REGDTVIIE 3404
+ + + +S + K + KP + +GD IIE
Sbjct: 5965 EAVFTKNLANIEVS-ETDTIKLVCEVSKPGAEVIWYKGDEEIIE 6007
Score = 50.8 bits (116), Expect = 8e-05
Identities = 27/80 (33%), Positives = 41/80 (51%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G+ V L +V PTV+W ++G LL + + L TLE+ + DS +
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGD 12868
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y+ T EN +G+ S + LKV
Sbjct: 12869 YTITAENSSGSKSATIKLKV 12888
Score = 50.8 bits (116), Expect = 8e-05
Identities = 75/312 (24%), Positives = 120/312 (38%), Gaps = 33/312 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P +P V + N +++W + + + Y VE + RWV TP++
Sbjct: 14074 PPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVER---REKKSLRWVRAIKTPVS 14130
Query: 3007 SF--DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
L++G Y FRV+ NR G G S+ S S+ + A P P +
Sbjct: 14131 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPG-----PPSNPHVT 14185
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVE-EEAG--RMTSQFNGFDCCLT---IKDINIDD 3118
T GKP G+ VE ++ G G +T + D+ +
Sbjct: 14186 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKE 14245
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
+ + A N G AV+ D + ++RE + + E D + T+ +R
Sbjct: 14246 KYNFRISAINDAGVGEP----AVIPDVEI------VEREMAPDFELDAELRRTLVVR--- 14292
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
A +R+ + G P P+V+W KD + R N E F L I N D G +
Sbjct: 14293 --AGLSIRIFVPIKGRPAPEVTWTKD--NINLKNRANIENTESFTLLIIPECNRYDTGKF 14348
Query: 3239 EVTARNNSGAVS 3250
+T N +G S
Sbjct: 14349 VMTIENPAGKKS 14360
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/249 (22%), Positives = 107/249 (42%), Gaps = 32/249 (12%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
++ L +G EY FRV N YG GE ++T+ + A P+ ++I+ +
Sbjct: 14428 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMD-----ITKS 14482
Query: 3067 TANLTCSVK----GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
T +L G + G V ++ + ++ +T+ G +C ++++ +E +
Sbjct: 14483 TVSLAWPKPKHDGGSKITGYV-IEAQRKGSDQWTHITT-VKGLEC--VVRNLTEGEEYTF 14538
Query: 3123 SCEATNTHGK-ASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
A N+ G+ A +R +V ++T+ ++ G Y + D
Sbjct: 14539 QVMAVNSAGRSAPRESRPVIVKEQTMLP---------ELDLRGIYQKLVIAKAGDN---- 14585
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEV 3240
+++ V+G P P V+W K G++++ +R ++ T L I D G Y +
Sbjct: 14586 ---IKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 14641
Query: 3241 TARNNSGAV 3249
TARN G V
Sbjct: 14642 TARNIVGEV 14650
Score = 50.8 bits (116), Expect = 8e-05
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EE 3093
S TS + G+ G P+ ++ LP + I G+ + C+ G+P P V W G ++ +
Sbjct: 26817 SSTSKMLKAGIRGIPPK-IEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 26875
Query: 3094 EAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
E GR + L I D+ D G Y+ N G S + +
Sbjct: 26876 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 50.4 bits (115), Expect = 1e-04
Identities = 80/330 (24%), Positives = 123/330 (37%), Gaps = 47/330 (14%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTT--APVLAYKVESWLIGAEGGARWVEL 3000
P VP+ P P +VD ++ VSL W +DP+ T +P+ Y +E W
Sbjct: 13675 PFDVPDA-PPPPNIVDVRHDSVSLTW--TDPKKTGGSPITGYHLE---FKERNSLLWKRA 13728
Query: 3001 GITPLN--SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL----AGDRPEFVD 3054
TP+ F L +G EY FRV N G G+ S S + V L +PE ++
Sbjct: 13729 NKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPV-VALDPIDPPGKPEVIN 13787
Query: 3055 ILPGQLKILAGETA-----NLT-CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
I + ++ E LT V+ + +P WMK H N +C
Sbjct: 13788 ITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANH------------VNVPECA 13835
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYAR-LAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
T+ D+ + + A NT G S + + + +EA + ++
Sbjct: 13836 FTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP-------TIVLDPTIK 13888
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
T++ D V ++G P PK SW K G+++ L I
Sbjct: 13889 DGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTI 13942
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
D G Y +TA N G H + V
Sbjct: 13943 KYATRKDAGEYTITATNPFGTKVEHVKVTV 13972
Score = 50.0 bits (114), Expect = 1e-04
Identities = 56/206 (27%), Positives = 89/206 (43%), Gaps = 33/206 (16%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
E +TS+ + V G R +F+ L Q + GETA C + + + VVW KN ++
Sbjct: 5062 EGKKTSARLFV--TGIRLKFMSPLEDQT-VKEGETATFVCELSHEKMH-VVWFKNDAKLH 5117
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
+ S G L +K++ +DD + + + S+ A+L V+ EAD
Sbjct: 5118 TSRTVLISS-EGKTHKLEMKEVTLDDISQIKAQVK----ELSSTAQLKVL------EAD- 5165
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
P FT++L D+ + L C+V P V W+KDGEE+V
Sbjct: 5166 ---------------PYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSP 5208
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ + D L+I +L D G Y
Sbjct: 5209 KYSIKADGLRRILKIKKADLKDKGEY 5234
Score = 50.0 bits (114), Expect = 1e-04
Identities = 79/348 (22%), Positives = 131/348 (37%), Gaps = 37/348 (10%)
Query: 2915 IVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGN---NWVSLAWPKS 2971
++ E +S + +P + +P P + + N N ++L W +
Sbjct: 21619 LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP 21678
Query: 2972 DPQTTAPVLAYKVESWLIGAEGGARWVE-LGITPLNS--FDAFNLKQGEEYHFRVTPRNR 3028
+ + + Y +E + RWV+ + P++ F L +G EY F V N
Sbjct: 21679 ESDGGSEIQQYILER---REKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENA 21735
Query: 3029 YGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVK-GKPVPGVVWMKN 3087
G G +S S I + P P +K+ +T+ T S++ KPV
Sbjct: 21736 AGVGPASGISRLIKCREPVNPPG----PPTVVKVT--DTSKTTVSLEWSKPVFDGGMEII 21789
Query: 3088 GHEVEEEAGRMTS--QFNGFDCC---LTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
G+ +E + + N C T+ D+ +E ++ A N GK + V
Sbjct: 21790 GYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDS----CEV 21845
Query: 3143 TDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWY 3202
T T+ D R E D F + V+A +RL G P P W
Sbjct: 21846 TG-TIKAVD------RLTAPELDIDANFK---QTHVVRAGASIRLFIAYQGRPTPTAVWS 21895
Query: 3203 KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
K + R + + + F TL + N +D G Y +T NNSG+ S
Sbjct: 21896 KPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKS 21941
Score = 49.6 bits (113), Expect = 2e-04
Identities = 65/247 (26%), Positives = 97/247 (39%), Gaps = 30/247 (12%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI--LA 3064
SF NL G EY+FRVT N YG G + + LA D D P +L++ +
Sbjct: 12259 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPV---LASDPLSEPDP-PRKLEVTEMT 12314
Query: 3065 GETANLTCSVK----GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
+A L G + G ++ + E E+ A R T D L + + +
Sbjct: 12315 KNSATLAWLPPLRDGGAKIDG--YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKY 12372
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
++ A N G + R A V+EA +L PP+ M ++
Sbjct: 12373 KFRVAARNAVGVS--LPREA----EGVYEAKEQL-----------LPPKILMP-EQITIK 12414
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
A +R+ V G P P W K +EVV ++ + L I D G Y +
Sbjct: 12415 AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSL 12474
Query: 3241 TARNNSG 3247
TA N+SG
Sbjct: 12475 TAENSSG 12481
Score = 49.6 bits (113), Expect = 2e-04
Identities = 60/243 (24%), Positives = 103/243 (42%), Gaps = 27/243 (11%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
L +G Y+FRV P N YG GE +TS ++ L + P ++P +L+++ + +T
Sbjct: 23104 LVEGTMYYFRVLPENIYGIGEPCETSDAV---LVSEVP----LVPAKLEVVDVTKSTVTL 23156
Query: 3073 SVKGKPVPGVVWMKNGHEVEE-EAG--RMTSQFNGFDCCL--TIKDINIDDEGRYSCEAT 3127
+ + KP+ G+ +E +AG R L T+ +N ++ + A
Sbjct: 23157 AWE-KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQ 23215
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G + + VT + D ++ ++ PQ T+ V A PV L
Sbjct: 23216 NEKGVSEPRETVTAVTVQ-----DLRVL----PTIDLSTMPQKTIH-----VPAGRPVEL 23261
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
+ G PPP SW+ G ++ +R + L I T + D G Y + +N +G
Sbjct: 23262 VIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 23321
Query: 3248 AVS 3250
S
Sbjct: 23322 TTS 23324
Score = 49.2 bits (112), Expect = 3e-04
Identities = 44/186 (23%), Positives = 76/186 (40%), Gaps = 31/186 (16%)
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED-SGTYTCKAENSVWTDQITHFV 2782
++ W+ ++K +PSD +++ L ID ED G Y C+A N
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQ-DQNTYTLVIDKVNTEDHQGEYVCEALND---------- 4319
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
S T+ K + +++ P + +VA G EI+ P
Sbjct: 4320 ---------SGKTATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEIQSAPNV 4366
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLY--TLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
R +W + GR E+Y + + + Y +L + + G YTC+A + +G+V A
Sbjct: 4367 RFQWFKAGR---EIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4423
Query: 2900 ITVVQP 2905
+TV P
Sbjct: 4424 LTVTVP 4429
Score = 49.2 bits (112), Expect = 3e-04
Identities = 48/184 (26%), Positives = 84/184 (45%), Gaps = 17/184 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT-L 2651
K + LT+ V GS C ++S S TW ++G + K+R + DG L
Sbjct: 4622 KEIKDIILTESEFV-GSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRF-IADGKDRKL 4678
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE- 2710
+++ SD+ EY+C + N +++A L V +P F +++ + + + +
Sbjct: 4679 HIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV------EELPVRFVKTLEEEVTVVKGQP 4732
Query: 2711 LVLECRIRGQPLPKITWFKDDK-QIPSDGRYQAFYLADGVCR-LAIDNPTPEDSGTYTCK 2768
L L C + + + W KD K + GR + G+ R L I++ D+GTYT
Sbjct: 4733 LYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVI--GLMRALTINDADDTDAGTYTVT 4788
Query: 2769 AENS 2772
EN+
Sbjct: 4789 VENA 4792
Score = 49.2 bits (112), Expect = 3e-04
Identities = 51/191 (26%), Positives = 71/191 (37%), Gaps = 12/191 (6%)
Query: 2962 NWVSLAWPKSDPQTTAPVLAYKVE--SWLIGAEGGARWVELGITPLNS--FDAFNLKQGE 3017
N V L+W +PV Y VE +W W + + F +L +G
Sbjct: 9529 NTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGG 9588
Query: 3018 EYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGK 3077
EY FRV N G + S T D P +D L +++ G N+ +KG
Sbjct: 9589 EYEFRVKAVNAAGVSKPSATVGPCDCQRP-DMPPSID-LKEFMEVEEGTNVNIVAKIKGV 9646
Query: 3078 PVPGVVWMKNGHEV--EEEAGRMTSQFNGF----DCCLTIKDINIDDEGRYSCEATNTHG 3131
P P + W K + +E + N C L I D G Y+ A N G
Sbjct: 9647 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 9706
Query: 3132 KASTYARLAVV 3142
AS RL V+
Sbjct: 9707 TASKEMRLNVL 9717
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/305 (22%), Positives = 111/305 (36%), Gaps = 29/305 (9%)
Query: 2961 NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR-WVELGITPLN-SFDAFNLKQGEE 3018
N L W + +P+ Y +E E R W + T + L QG+
Sbjct: 10133 NESCKLTWFSPEDDGGSPITNYVIEK----RESDRRAWTPVTYTVTRQNATVQGLIQGKA 10188
Query: 3019 YHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKP 3078
Y FR+ N G G +TS ++ + PE + L ++K + T LT +
Sbjct: 10189 YFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDL--EVKEVTKNTVTLTWNPPKYD 10246
Query: 3079 VPGVV--WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
+ ++ + E + N T+K + D Y A N G+
Sbjct: 10247 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPS 10306
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRLTCQVIGSP 3195
+T K E + PP + RD+ ++ LT + G P
Sbjct: 10307 FCTKPIT----------CKDELA-------PPTLHLDFRDKLTIRVGEAFALTGRYSGKP 10349
Query: 3196 PPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL 3255
PKVSW+KD +V+ D R + LE D G Y V N++G+ C +
Sbjct: 10350 KPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQV 10409
Query: 3256 -VVDK 3259
VVD+
Sbjct: 10410 NVVDR 10414
Score = 49.2 bits (112), Expect = 3e-04
Identities = 55/252 (21%), Positives = 106/252 (42%), Gaps = 24/252 (9%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
+F NL++G Y+FRV N YG G ++T+ + V + P + PG++ ++ +
Sbjct: 18759 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS---EPP----LPPGRVTLV--D 18809
Query: 3067 TANLTCSVKG-KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
T ++K KP G+ VE + T + C +K + G
Sbjct: 18810 VTRNTATIKWEKPESDGGSKITGYVVEMQ----TKGSEKWSTCTQVKTLEATISGL---- 18861
Query: 3126 ATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPV 3185
T G+ + R+A V ++ +D + + + P + V+A +
Sbjct: 18862 ---TAGEEYVF-RVAAVNEKG--RSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 18915
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
++ G P V+W KDG+ + R N + +L I + +D G YE+ N+
Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 18975
Query: 3246 SGAVSCHCGLVV 3257
+G+++ ++V
Sbjct: 18976 AGSITVPITIIV 18987
Score = 48.8 bits (111), Expect = 3e-04
Identities = 80/323 (24%), Positives = 126/323 (39%), Gaps = 49/323 (15%)
Query: 2950 IPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT-PL 3005
+PG P V D L+W D + Y +E I G W ++
Sbjct: 9414 VPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTID---GKAWTKVNPDCGS 9470
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI--L 3063
+F +L ++Y FRV NR+G G +T I A D P + P +LKI +
Sbjct: 9471 TTFVVPDLLSEQQYFFRVRAENRFGIGPPVET---IQRTTARD-PIYPPDPPIKLKIGLI 9526
Query: 3064 AGETANLTCSVK----GKPVPGVV-----WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
T +L+ G PV + W G ++EA R ++ + + T++D+
Sbjct: 9527 TKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTG--TKKEAWRQCNKRDVEELQFTVEDL 9584
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRL 3174
E + +A N G + A TV D + D PP ++
Sbjct: 9585 VEGGEYEFRVKAVNAAGVSKPSA--------TVGPCDCQ---------RPDMPPSIDLK- 9626
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYK-------DGEEVVYDKRRNKYQDEQFHTLEI 3227
V+ V + ++ G P P ++W+K + E V+YD NK + TL I
Sbjct: 9627 EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVI 9686
Query: 3228 APTNLDDGGVYEVTARNNSGAVS 3250
+ D G+Y +TA NN G S
Sbjct: 9687 PQSRRSDTGLYTITAVNNLGTAS 9709
Score = 48.8 bits (111), Expect = 3e-04
Identities = 52/191 (27%), Positives = 78/191 (40%), Gaps = 20/191 (10%)
Query: 2951 PGEPCVVDGGNNWVSLAW--PKSD--PQTTAPVLAYKVES---WLIGAEGGARWVELGIT 3003
P P V D + L W P D + T ++ YK E W G + R +L +T
Sbjct: 9927 PPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVT 9986
Query: 3004 PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDI-LPGQLK 3061
LK+G Y FRV+ N G GE + + I + P+ +D + ++
Sbjct: 9987 --------GLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV 10038
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ AG + V GKP P V W N + +EA T + + IK+ +G
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQGV 10095
Query: 3122 YSCEATNTHGK 3132
YS A N G+
Sbjct: 10096 YSLLAKNEAGE 10106
Score = 48.8 bits (111), Expect = 3e-04
Identities = 72/325 (22%), Positives = 127/325 (39%), Gaps = 34/325 (10%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG+P + + ++ +SL W + V + VE W ++ +P++ +
Sbjct: 21263 PGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEK---KERNSILWQKVNTSPISGREY 21319
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETA 3068
A L +G +Y FRV N G S S D P D + + ET
Sbjct: 21320 RATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYID-----VTRETI 21374
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEEAGR---MTSQFNGF-DCCLTIKDINIDDEGRYSC 3124
L + P+ G+ +E+ G + F +C T+ ++ D +
Sbjct: 21375 TLKWN---PPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRI 21431
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G S ++ + + + R+ + ++ P++ L +++
Sbjct: 21432 IARNAVGTISPPSQSSGII----------MTRDENVPPIVEFGPEYFDGLI---IKSGES 21478
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHT-LEIAPTNLDDGGVYEVTA 3242
+R+ V G P P+V+W+KDG E+ +KR N + D T L + D GVY V A
Sbjct: 21479 LRIKALVQGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 21536
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAP 3267
+N SG+ + V V P
Sbjct: 21537 KNASGSAKAEIKVKVQDTPGKVVGP 21561
Score = 48.4 bits (110), Expect = 5e-04
Identities = 60/221 (27%), Positives = 90/221 (40%), Gaps = 38/221 (17%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EF+ P L+IL GE A CS+ + P V W K + E + +G L
Sbjct: 6056 EFIS-KPQNLEILEGEKAEFVCSISKESFP-VQW-KRDDKTLESGDKYDVIADGKKRVLV 6112
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+KD + D G Y G A A L V+ KL+
Sbjct: 6113 VKDATLQDMGTYVVMV----GAARAAAHLTVIE---------KLR--------------I 6145
Query: 3171 TMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY---QDEQFHTLEI 3227
+ L+D RV+ V C+V + K W+++ EE ++D +KY Q + +TL I
Sbjct: 6146 VVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRN-EEAIFDS--SKYIILQKDLVYTLRI 6201
Query: 3228 APTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAP 3267
+LDD Y V+ N+ G V L+V++ V P
Sbjct: 6202 RDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEP 6242
Score = 48.4 bits (110), Expect = 5e-04
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
++ L + G + + A V P V+W +DG L+P+ M + R+ L L +V
Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVN 12862
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
+D+G YT TA N G S + K++V+ D+ PP + + YS M +P
Sbjct: 12863 RKDSGDYTITAENSSGSKSATIKLKVL--DKPG----PPASVKINKMYSDRAMLSWEP 12914
Score = 48.0 bits (109), Expect = 6e-04
Identities = 40/143 (27%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT-VENENGAISTSANLKV 2683
V WY++G+ + KYR + L +L SD+ +YSC VE+EN + T+A L V
Sbjct: 2159 VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN--VKTTAKLIV 2216
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
E + + F + ++D LEC + + + + W+ +D ++ S+G+Y
Sbjct: 2217 ----EGAVV--EFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKY-TI 2268
Query: 2744 YLADGVCRLAIDNPTPEDSGTYT 2766
G L + + T ED G Y+
Sbjct: 2269 TSRRGRQNLTVKDVTKEDQGEYS 2291
Score = 48.0 bits (109), Expect = 6e-04
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
++ G+ +V+ KP V W NG E++E + + +G L I D + DD G
Sbjct: 25887 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGV-LTLEILDCHTDDSG 25945
Query: 3121 RYSCEATNTHGKASTYARLAV 3141
Y TN G+AS YA L V
Sbjct: 25946 TYRAVCTNYKGEASDYATLDV 25966
Score = 47.6 bits (108), Expect = 8e-04
Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A V L V G P P VSW KDG + + TLE+ N D G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 3239 EVTARNNSGAVSCHCGL-VVDK 3259
+TA N+SG+ S L V+DK
Sbjct: 12870 TITAENSSGSKSATIKLKVLDK 12891
Score = 47.2 bits (107), Expect = 0.001
Identities = 79/330 (23%), Positives = 122/330 (36%), Gaps = 52/330 (15%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++ +S + + EF+ L L++ E A C + + V W K+G E++
Sbjct: 5860 DAKDFKTSCNLNVVPPHVEFLRPLT-DLQVREKEMARFECELSRENAK-VKWFKDGAEIK 5917
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
+ + G L I +DDE YSCE A T L V+ + V
Sbjct: 5918 K-GKKYDIISKGAVRILVINKCLLDDEAEYSCEVRT----ARTSGMLTVLEEEAV----- 5967
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
FT L + V T ++L C+V P +V WYK EE++
Sbjct: 5968 -----------------FTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETG 6009
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
R + + L I +L+D G Y + + G V H +A EF
Sbjct: 6010 RYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-----------ELAAEFI 6058
Query: 3271 CGLEPLYKLH-EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
+ L L E E S E++P V W RD L + + D ++ L +
Sbjct: 6059 SKPQNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVK 6114
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
T +D G Y VG A + + VI
Sbjct: 6115 DATLQDMGTYVVM----VGAARAAAHLTVI 6140
Score = 47.2 bits (107), Expect = 0.001
Identities = 72/265 (27%), Positives = 106/265 (40%), Gaps = 45/265 (16%)
Query: 3003 TPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKI 3062
T + D L +G+EY FRV +N++G G + IG LA D P P +L
Sbjct: 8752 TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVE----IGPILAVD-PLGPPTSPERLTY 8806
Query: 3063 LAGETANLTCSVK------GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI-- 3114
+ +T K G P+ G + K H+ + + R+ + C T +
Sbjct: 8807 TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHD-KPDFERVNKRL-----CPTTSFLVE 8860
Query: 3115 NIDDEGRYS--CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
N+D+ Y +A N G++ L VV KL+ V GD T+
Sbjct: 8861 NLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLR----LSVRGD-----TI 8911
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQ--------DEQFHT 3224
+V+A PV + V G P PK+ W K+ E V +K + Q E
Sbjct: 8912 -----KVKAGEPVHIPADVTGLPMPKIEWSKN--ETVIEKPTDALQITKEEVSRSEAKTE 8964
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAV 3249
L I +D G Y VTA N G+V
Sbjct: 8965 LSIPKAVREDKGTYTVTASNRLGSV 8989
Score = 47.2 bits (107), Expect = 0.001
Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
Y + G +L+I + P +TW +DG+ L+ + R +T D L++ D
Sbjct: 16742 YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLDLTTLSIKETHKDDG 16800
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
G Y T +N VG+ + S +E++ D+ P+ P
Sbjct: 16801 GQYGITVANVVGQKTAS--IEIVTLDKPDPPKGP 16832
Score = 47.2 bits (107), Expect = 0.001
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 3/112 (2%)
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
E+ ENE G + S P + ++D L C+I G+PL
Sbjct: 24005 EFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 24064
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSV 2773
P I W++ K++ +Y+ +DG L + ED G YTC A N V
Sbjct: 24065 PDIKWYRFGKELIQSRKYK--MSSDGRTHTLTVMTEEQEDEGVYTCIATNEV 24114
Score = 47.2 bits (107), Expect = 0.001
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 4/116 (3%)
Query: 2660 DSAEYSCTVENEN-GAISTSANLK--VYPSFEASPIPPTFTRSIRDTFHLAENELVLECR 2716
+ EY V+ EN G S + + + P + P F +R+ ++ L C+
Sbjct: 24394 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 24453
Query: 2717 IRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ G P P + W++ K+I +DG +Y+ G +L I + T +D+ Y +A N
Sbjct: 24454 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATN 24509
Score = 46.8 bits (106), Expect = 0.001
Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 18/162 (11%)
Query: 3198 KVSWYKDGEEVVYDKRRNKYQDE-QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
+V W+K+ + + + R QDE + H++ ++DD V A +S L
Sbjct: 5461 RVKWFKNDQRL-HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMG----MSSEAKLT 5515
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIM 3316
V +G P F L+ Y E DE+ + + V W++DG ++PS+ A++
Sbjct: 5516 VLEG-----DPYFTGKLQD-YTGVEKDEVILQCEISK-ADAPVKWFKDGKEIKPSKNAVI 5568
Query: 3317 TLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
D ++ L L D G YTC + G TSGK+++
Sbjct: 5569 KADGKKRM-LILKKALKSDIGQYTC----DCGTDKTSGKLDI 5605
Score = 46.8 bits (106), Expect = 0.001
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA 3010
PG+P V D G V L W K + A + +Y +E G + R E G+ P
Sbjct: 7490 PGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAE-GV-PTTQHLL 7547
Query: 3011 FNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
L +G+EY FRV N+ G E S+ S +
Sbjct: 7548 PGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 7578
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P T L D EG + C V S +D V+WY + +R + LE+
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A P D Y+ N G +S++ANL +
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 46.4 bits (105), Expect = 0.002
Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 6/142 (4%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L++ G A TC ++ P W K G E+ E+ + + + + + L I + D
Sbjct: 4346 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCSIRSSKYISSLEILRTQVVDC 4404
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR---- 3175
G Y+C+A+N +G S A L V + KL ER E + + + +R R
Sbjct: 4405 GEYTCKASNEYGSVSCTATLTVTVPGGEKKV-RKLLPERKPEPKEEVVLKSVLRKRPEEE 4463
Query: 3176 DRRVQATYPVRLTCQVIGSPPP 3197
+ +V+ ++ + PPP
Sbjct: 4464 EPKVEPKKLEKVKKPAVPEPPP 4485
Score = 46.4 bits (105), Expect = 0.002
Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 18/199 (9%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGI 3002
P PER+ + + ++L W + +P+ Y +E R V +
Sbjct: 8797 PPTSPERLT----YTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFER-VNKRL 8851
Query: 3003 TPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF---VDILP 3057
P SF NL + + Y FRV N G S+ S + V + D P + +
Sbjct: 8852 CPTTSFLVENLDEHQMYEFRVKAVNEIG---ESEPSLPLNVVIQDDEVPPTIKLRLSVRG 8908
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE--EAGRMTSQ---FNGFDCCLTIK 3112
+K+ AGE ++ V G P+P + W KN +E+ +A ++T + + L+I
Sbjct: 8909 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 8968
Query: 3113 DINIDDEGRYSCEATNTHG 3131
+D+G Y+ A+N G
Sbjct: 8969 KAVREDKGTYTVTASNRLG 8987
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G R V++ P+ V WY +GV L+ S + T + G + L + T D+G Y
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRA 25949
Query: 3342 TASNEVGRASTSGKVEVIGTDQTS 3365
+N G AS ++V G D T+
Sbjct: 25950 VCTNYKGEASDYATLDVTGGDYTT 25973
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 18/140 (12%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS----- 3353
VTWY+DG +L+ + DG EL + +T D G Y C S E G + T+
Sbjct: 26252 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 26311
Query: 3354 -------GKVEVIGTDQTSEPRIPPVVISPDV------PYSKEPMFIRKPRSSEAREGDT 3400
KV I + S+ + ++ P S +P+ + + +
Sbjct: 26312 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSV 26371
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
+ G+P+P W +D
Sbjct: 26372 AKFAVKATGEPRPTAIWTKD 26391
Score = 46.0 bits (104), Expect = 0.002
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 6/162 (3%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
V W +G E+ + TL I + D G+ ++ G V C L +
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 26630
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
K + AP F ++EG + + + PS + W+++ + + S ++
Sbjct: 26631 KELSD--APAFISQPRS-QNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 26687
Query: 3319 DRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
R+ +E+ A+V+ D+G YT A N G+ S + + V+
Sbjct: 26688 SRNVYSLEIRNASVS--DSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 8/137 (5%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
+++ PS EA P F R T ++ R+ G+P P+ W+K+ +I R
Sbjct: 2023 IELSPSMEA---PKIFERIQSQTVGQG-SDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVV 2796
++ D VC L I + T EDS + KA N F+ ++ +Q +VV
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVV 2138
Query: 2797 TAEKTRIARQSLESRRP 2813
EK +A E+ P
Sbjct: 2139 AKEKDTMATFECETSEP 2155
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD LR+SA+++ P VTW ++ R P++ I ++E+ AA D G+Y+
Sbjct: 10736 GDTLRLSAIIKGVPFPKVTWKKED-RDAPTKARIDVTPVGSKLEIRNAA--HEDGGIYSL 10792
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPR 3368
T N G + S KV V+ D+ PR
Sbjct: 10793 TVENPAGSKTVSVKVLVL--DKPGPPR 10817
Score = 45.6 bits (103), Expect = 0.003
Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 23/254 (9%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
S+ L++G Y+FRV N YG G ++T+ S+ A +RP + PG++ ++
Sbjct: 15512 SWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVK---ASERP----LPPGKITLMDVT 15564
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA 3126
+++ S + KP G+ VE + T + + C T+K G
Sbjct: 15565 RNSVSLSWE-KPEHDGGSRILGYIVEMQ----TKGSDKWATCATVKVTEATITGLIQ--- 15616
Query: 3127 TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVR 3186
G+ ++ R++ ++ + +D + + PP F + V A ++
Sbjct: 15617 ----GEEYSF-RVSAQNEKGI--SDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 15669
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
+ IG P P V+W+KD + R N E L I +D G Y V N++
Sbjct: 15670 VDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSA 15729
Query: 3247 G-AVSCHCGLVVDK 3259
G A+ +V+DK
Sbjct: 15730 GEAIETLNVIVLDK 15743
Score = 45.2 bits (102), Expect = 0.004
Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 5/108 (4%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLD 2635
S ISE ++++ KP D +EG ++ + + PTV+W+++G V
Sbjct: 7875 SEISEN-VVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS 7933
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
++L + + LEV +V +D+ Y+ T+EN+ G+ + S N+KV
Sbjct: 7934 DRLTMKNDHISA--HLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 45.2 bits (102), Expect = 0.004
Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 8/160 (5%)
Query: 2652 EVLNAVPSDSAEYSCTVENENGAIS--TSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
EV V E+ N G S + + + E P + +DT +
Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAG 16061
Query: 2710 E-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
E ++ I G+P+P I W K D+++ + R + D L++ + DSG Y K
Sbjct: 16062 ESFKVDADIYGKPIPTIQWIKGDQELSNTARLE-IKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 2769 AENSVWTDQITHFVNFTGR----ESQVSPNVVTAEKTRIA 2804
A+N +T V R E V + VTAEK +A
Sbjct: 16121 AKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLA 16160
Score = 45.2 bits (102), Expect = 0.004
Identities = 76/309 (24%), Positives = 119/309 (38%), Gaps = 34/309 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P V + + + W + ++ Y +E + WV+L TP+ F
Sbjct: 18011 PGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ---KEKNSILWVKLNKTPIQDTKF 18067
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETA 3068
L +G EY F+V+ N G G+ S+ S +A D + PG+ + +
Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF---VARDPCD----PPGRPEAIVITRN 18120
Query: 3069 NLTCSVKGKPVPGVVWMKNGHEVEEE---AGR-MTSQF-NGFDCCLTIKDINIDDEGRYS 3123
N+T K KP G+ VE++ GR M + F N + T+ + D +
Sbjct: 18121 NVTLKWK-KPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFR 18179
Query: 3124 CEATNTHGKASTYA-RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
A N G S + +T R E DA +A ++ Y + + V
Sbjct: 18180 VIARNAAGNFSEPSDSSGAITARD--EIDAP-----NASLDPKYKDVIVVHAGETFV--- 18229
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE-QFHTLEIAPTNLDDGGVYEVT 3241
L + G P P V W KDG+E+ R + + Q TL + DGG Y +
Sbjct: 18230 ----LEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILK 18285
Query: 3242 ARNNSGAVS 3250
N G S
Sbjct: 18286 LSNVGGTKS 18294
Score = 45.2 bits (102), Expect = 0.004
Identities = 25/76 (32%), Positives = 31/76 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G + +V S V WY NGV L K G++TLE+L+ DS Y
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 25950
Query: 2668 VENENGAISTSANLKV 2683
N G S A L V
Sbjct: 25951 CTNYKGEASDYATLDV 25966
Score = 44.8 bits (101), Expect = 0.006
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
Score = 44.8 bits (101), Expect = 0.006
Identities = 49/167 (29%), Positives = 74/167 (44%), Gaps = 19/167 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGL-ITLE 2652
P F+ L D+TAVE + L C V S D V W+++G + KY K DGL L+
Sbjct: 5166 PYFTVKLHDKTAVEKDEITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIK-ADGLRRILK 5222
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR-SIRDTFH----LA 2707
+ A D EY C + G T AN+ V P + +T H L+
Sbjct: 5223 IKKADLKDKGEYVC----DCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELS 5278
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
E ++ + +++GQPL D +I DG+ L + C+L +
Sbjct: 5279 EPDVHGQWKLKGQPLTA----SPDCEIIEDGKKHILILHN--CQLGM 5319
Score = 44.8 bits (101), Expect = 0.006
Identities = 77/309 (24%), Positives = 123/309 (39%), Gaps = 35/309 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--F 3008
PG P + + + W + +PV+ Y +E W ++ T ++ F
Sbjct: 16929 PGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER---KERNSILWTKVNKTIIHDTQF 16985
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE-T 3067
A NL++G EY FRV N G G++S+ S D P P + + E T
Sbjct: 16986 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG----TPEPIMVKRNEIT 17041
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEE---AGR-MTSQF-NGFDCCLTIKDINIDDEGRY 3122
T KPV M G+ VE+ GR M + F N + T+ + D +
Sbjct: 17042 LQWT-----KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEF 17096
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
A N G S + + T + + +L R + D P+F + V A
Sbjct: 17097 RVIAKNAAGAIS---KPSDSTGPITAKDEVELPR-----ISMD--PKFRDTI---VVNAG 17143
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD-DGGVYEVT 3241
RL V G P P + W + G++ + + R + ++ F L I + DGG Y +
Sbjct: 17144 ETFRLEADVHGKPLPTIEWLR-GDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILR 17202
Query: 3242 ARNNSGAVS 3250
A N +G+ S
Sbjct: 17203 ASNVAGSKS 17211
Score = 44.4 bits (100), Expect = 0.007
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 12/137 (8%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELV-LECRI 2717
+ EY V+ N A + + V P P +PP+ +++ + E V + +I
Sbjct: 9586 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSI--DLKEFMEVEEGTNVNIVAKI 9643
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFY-------LADGVCRLAIDNPTPEDSGTYTCKAE 2770
+G P P +TWFK + P D + Y + D C L I D+G YT A
Sbjct: 9644 KGVPFPTLTWFKAPPKKP-DNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAV 9702
Query: 2771 NSVWTDQITHFVNFTGR 2787
N++ T +N GR
Sbjct: 9703 NNLGTASKEMRLNVLGR 9719
Score = 44.4 bits (100), Expect = 0.007
Identities = 42/140 (30%), Positives = 66/140 (47%), Gaps = 15/140 (10%)
Query: 3230 TNLDDGGVYE--VTARNNSGAVSC---HCGLVVDKGIRAYVAPEFCCGLEPLYK----LH 3280
T+L +GG YE + A+N +GA+S ++ K Y AP L+P K +
Sbjct: 13839 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKD--EYEAPTIV--LDPTIKDGLTIK 13894
Query: 3281 EGDELRISAV-VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
GD + ++A+ + P +W + G +RPS +T + L + T +DAG Y
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM-LTIKYATRKDAGEY 13953
Query: 3340 TCTASNEVGRASTSGKVEVI 3359
T TA+N G KV V+
Sbjct: 13954 TITATNPFGTKVEHVKVTVL 13973
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+P+ V + P +++L GETA C V G P P V W NG ++ ++ R +++G
Sbjct: 1794 KPDIV-LYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIH-Y 1850
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I D D G A N G +L +
Sbjct: 1851 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 44.0 bits (99), Expect = 0.010
Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 16/212 (7%)
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +K VEG +F L+D V +Y L C ++ + WY + E+
Sbjct: 2205 DENVKTTAKLIVEGAVV-EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKS 2262
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+ + L + +D G Y C L + A +
Sbjct: 2263 NGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT----CKLKMKPRPIAILQ---- 2314
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL K+ EGD +++ V GV W +DG ++PS R + +D+ + L +
Sbjct: 2315 -GLSD-QKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHM-LLIED 2370
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+T DAG Y+ T +G STSG+V V D
Sbjct: 2371 MTKEDAGNYSFTIP-ALG-LSTSGRVSVYSVD 2400
Score = 44.0 bits (99), Expect = 0.010
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 7/118 (5%)
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L L I+G P PK+TW K+D+ P+ R + +L I N ED G Y+ E
Sbjct: 10739 LRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS---KLEIRNAAHEDGGIYSLTVE 10795
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP--HFGNVLTDYQVAR 2826
N + ++ V + P + + R L + P G+V+T+Y V R
Sbjct: 10796 NPAGSKTVS--VKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVER 10851
Score = 44.0 bits (99), Expect = 0.010
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 2/120 (1%)
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + + + + +NE G IS L V + IPP F LA +L
Sbjct: 15611 ITGLIQGEEYSFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 15669
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
++ G+P P +TW KD+ + R A + L I + ED G Y K NS
Sbjct: 15670 VDVPFIGRPTPAVTWHKDNVPLKQTTRVNA-ESTENNSLLTIKDACREDVGHYVVKLTNS 15728
Score = 44.0 bits (99), Expect = 0.010
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+G+P P +TW KD+K + SD RY + D L I T D+G Y EN V
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARY-SIENTDSSSLLTIPQVTRNDTGKYILTIENGV 20853
Score = 43.6 bits (98), Expect = 0.013
Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P F ++ G T +++ G P W +G+ + Y + V E G +L
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
+ T ++SG +T A + G ++ +T V+ + KP + K++ I G
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFV--EKLKNVNIKEGSQ 1526
Query: 2931 INISFRTQGEPKPKAV 2946
+ + R G P P V
Sbjct: 1527 LEMKVRATGNPNPDIV 1542
Score = 43.6 bits (98), Expect = 0.013
Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 2/107 (1%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
++ S K T+ + + PV + G K TC + S+ + W++ G +
Sbjct: 4322 KTATSAKLTVVKRAA--PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE 4379
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
K + + +LE+L D EY+C NE G++S +A L V
Sbjct: 4380 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 43.2 bits (97), Expect = 0.017
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L+D+ EG V+L V S V W ++G + + + L + +
Sbjct: 2316 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKE 2374
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ YS T+ +STS + VY +P+ +D + + VLEC++
Sbjct: 2375 DAGNYSFTIPALG--LSTSGRVSVYSVDVITPL--------KDVNVIEGTKAVLECKVSV 2424
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ + W+ +D+QI D R QA + RL I+ D G Y
Sbjct: 2425 PDVTSVKWYLNDEQIKPDDRVQAI-VKGTKQRLVINRTHASDEGPY 2469
Score = 43.2 bits (97), Expect = 0.017
Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCR- 2751
P FT ++D + ++E++L+C I P + WFKD K+I PS A ADG R
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSK---NAVIKADGKKRM 5576
Query: 2752 LAIDNPTPEDSGTYTC 2767
L + D G YTC
Sbjct: 5577 LILKKALKSDIGQYTC 5592
Score = 43.2 bits (97), Expect = 0.017
Identities = 57/243 (23%), Positives = 91/243 (37%), Gaps = 26/243 (10%)
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGE 3066
SF NL++G+ Y FRV N YG G+ +T ++ A P V LK+ +
Sbjct: 13347 SFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVK---ASQTPGPVV----DLKVRSVS 13399
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
++ + K KP G+ V+ E + + KD+ E +
Sbjct: 13400 KSSCSIGWK-KPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRV 13458
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N +G+ T + + VV V D LK P + + + P
Sbjct: 13459 SAENENGEG-TPSEITVVARDDVVAPDLDLK---------GLPDLCYLAKENSNFRLKIP 13508
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
++ G P P VSW K + + D R + TL + D G Y +T +N
Sbjct: 13509 IK------GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13562
Query: 3245 NSG 3247
+G
Sbjct: 13563 VAG 13565
Score = 43.2 bits (97), Expect = 0.017
Identities = 56/205 (27%), Positives = 86/205 (41%), Gaps = 15/205 (7%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---D 2702
D T+ L+ D+ E+ +N G IS + + PP R D
Sbjct: 22501 DNFFTVTALSE--GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 22558
Query: 2703 TFHL-AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ A ++LVL+ + G+P PKI W K DK++ + Y + I D
Sbjct: 22559 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSD 22617
Query: 2762 SGTYTCKAENSVWTDQITHFV---NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
SG YT +N+ T ++ V + G +++ + VT EK +A SL + G
Sbjct: 22618 SGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLA-WSLP--QEDGGAE 22674
Query: 2819 LTDYQVARGGTIGLQ-VEIRG-CPT 2841
+T Y V R T L V + G CPT
Sbjct: 22675 ITHYIVERRETSRLNWVIVEGECPT 22699
Score = 42.7 bits (96), Expect = 0.022
Identities = 58/243 (23%), Positives = 93/243 (38%), Gaps = 36/243 (14%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+D ++DD+ Y+ TN G+ A +V E D ++ E ++E
Sbjct: 6199 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVE-----EEDLRIV-EPLKDIETMEKK 6252
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
T + R+ T + W K+GEEV +D R + D+ H L I
Sbjct: 6253 SVTFWCKVNRLNVT----------------LKWTKNGEEVPFDNRVSYRVDKYKHMLTIK 6296
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
D G Y VTA + L+++ EF LE + E D+ S
Sbjct: 6297 DCGFPDEGEYIVTAGQDKSVAEL---LIIE------APTEFVEHLED-QTVTEFDDAVFS 6346
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASNEV 3347
+ + V WYR+G ++ ++ ++DG I L + D Y C +
Sbjct: 6347 CQL-SREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDECEYACGVEDRK 6403
Query: 3348 GRA 3350
RA
Sbjct: 6404 SRA 6406
Score = 42.7 bits (96), Expect = 0.022
Identities = 42/156 (26%), Positives = 59/156 (37%), Gaps = 3/156 (1%)
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
DN ++ KLV L T +V + Y + EN+ G S L + +A P
Sbjct: 6839 DNWIRCNMKLVPEL-TYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPT 6897
Query: 2695 TFTRSIRDTFH-LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
+ +D + N + + G P P TW DK + + R + L+ L
Sbjct: 6898 MDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS-AYAELV 6956
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
I D G YT K EN V T VN R S
Sbjct: 6957 ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPS 6992
Score = 42.7 bits (96), Expect = 0.022
Identities = 21/63 (33%), Positives = 30/63 (47%)
Query: 3195 PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCG 3254
P P VSW+KDG+EV R D LE+ + D G+Y +T N G+ +
Sbjct: 7917 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 7976
Query: 3255 LVV 3257
+ V
Sbjct: 7977 VKV 7979
Score = 42.7 bits (96), Expect = 0.022
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASP--IPPTFTRSIRDTFHLAENELVLECRI 2717
+ +Y V N A+ S + +EA +PP + T A +L +E +
Sbjct: 12368 EGKKYKFRVAARN-AVGVSLPREAEGVYEAKEQLLPPKILMPEQITIK-AGKKLRIEAHV 12425
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G+P P W K + ++ + + A + AD L I + T +DSG Y+ AENS TD
Sbjct: 12426 YGKPHPTCKWKKGEDEVVTSS-HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTD 12483
Score = 42.7 bits (96), Expect = 0.022
Identities = 30/118 (25%), Positives = 51/118 (43%), Gaps = 4/118 (3%)
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT--FTRSIRDTFHLAENE-LVLE 2714
P D E+ N G IS + +PP F D + E L ++
Sbjct: 21423 PGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIK 21482
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
++G+P+P++TWFKD +I + + G L + + T + G YT +A+N+
Sbjct: 21483 ALVQGRPVPRVTWFKDGVEIEKRMNMEITDVL-GSTSLFVRDATRDHRGVYTVEAKNA 21539
Score = 42.7 bits (96), Expect = 0.022
Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLY-TL 2870
PHF L + V L ++ G P V+W R+G+ + R+ +G Y L
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
++ VT+ ++ +Y RA + G+V A++ V P+ + P + G L GE
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGMGAVHAL--RGEV 24547
Query: 2931 INISFRTQGEPKP 2943
++I G+P P
Sbjct: 24548 VSIKIPFSGKPDP 24560
Score = 42.3 bits (95), Expect = 0.030
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 2685 PSFEASPI-------PPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPS 2736
PSF PI PPT RD + E L R G+P PK++WFKD+ +
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364
Query: 2737 DGRYQAFYLADGVCRLAID--NPTPEDSGTYTCKAENS 2772
D R ++ LA++ DSG Y ENS
Sbjct: 10365 DDR---THIKTTPATLALEKIKAKRSDSGKYCVVVENS 10399
Score = 42.3 bits (95), Expect = 0.030
Identities = 28/136 (20%), Positives = 50/136 (36%), Gaps = 1/136 (0%)
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA-EVEGDYPPQFTMRLRDRRVQATY 3183
+ T T S+Y A ++ + L+ + + +++ + + R V
Sbjct: 26020 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGE 26079
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
R +C G P P V+W + G+ + R + T EI+ D G Y V
Sbjct: 26080 SARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 26139
Query: 3244 NNSGAVSCHCGLVVDK 3259
N+ G L + K
Sbjct: 26140 NSEGKQEAEFTLTIQK 26155
Score = 41.9 bits (94), Expect = 0.039
Identities = 40/171 (23%), Positives = 70/171 (40%), Gaps = 15/171 (8%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN 2655
F L D+T E +C +S V WYRNG + KY+ + + L + +
Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQ-LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6386
Query: 2656 AVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLEC 2715
D EY+C VE+ + A L V IP R +D ++V
Sbjct: 6387 CRLDDECEYACGVEDR----KSRARLFV------EEIPVEIIRPPQDILEAPGADVVFLA 6436
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTY 2765
+ + ++ W +++ + ++Q +++G + RL I + P D G Y
Sbjct: 6437 ELNKDKV-EVQWLRNNMVVVQGDKHQ--MMSEGKIHRLQICDIKPRDQGEY 6484
Score = 41.9 bits (94), Expect = 0.039
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 2689 ASPIPPTFTRSIRDTFHL---AENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFY 2744
A +PP S+ L A + L+ + G+P+P ++W KD + P++G A
Sbjct: 12791 AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMA-- 12848
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ +C L + + +DSG YT AENS
Sbjct: 12849 MQRNLCTLELFSVNRKDSGDYTITAENS 12876
Score = 41.9 bits (94), Expect = 0.039
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 3/120 (2%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
++EG+ R S + P VTW R G L S R +T + + +++V D G
Sbjct: 26075 VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQASDEGN 26133
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEP-RIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
Y+ N G+ + + T + PP V SP+ P K P ++ P+ ++ E
Sbjct: 26134 YSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPE-PRVKSPEAVKSPKRVKSPE 26192
Score = 41.9 bits (94), Expect = 0.039
Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 2612 KLTCSVISS--SDPTVTWYRNGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTV 2668
KLTC V SS VTWY++G L ++ DG L++ N SD EY C +
Sbjct: 26237 KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI 26296
Query: 2669 ENENGAISTS 2678
E G T+
Sbjct: 26297 SGEGGTSKTN 26306
Score = 41.5 bits (93), Expect = 0.052
Identities = 45/171 (26%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTR--SIR-DTFHLAENELV-LECRIR 2718
E+ NE G S L V + +PPT S+R DT + E V + +
Sbjct: 8869 EFRVKAVNEIGESEPSLPLNVV--IQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVT 8926
Query: 2719 GQPLPKITWFKDDKQI--PSDG---RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
G P+PKI W K++ I P+D + ++ L+I ED GTYT A N +
Sbjct: 8927 GLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 8986
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
+ V R S VT K + ++ + G+ +T Y +
Sbjct: 8987 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9037
Score = 41.5 bits (93), Expect = 0.052
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 2961 NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS-FDAFNLKQGEEY 3019
+++V+ +W + P+ Y VE + WVEL T + + + A L G EY
Sbjct: 14676 SDFVTFSWDPPENDGGVPISNYVVE---MRQTDSTTWVELATTVIRTTYKATRLTTGLEY 14732
Query: 3020 HFRVTPRNRYGWG 3032
FRV +NRYG G
Sbjct: 14733 QFRVKAQNRYGVG 14745
Score = 41.1 bits (92), Expect = 0.068
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 26/254 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL EY+FRV N+ G G + +T + I DRP GE NL
Sbjct: 11566 NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRP--------------GEPENLH 11611
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEE--AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
+ KGK + W + ++ + + + G D + +I E Y +
Sbjct: 11612 IADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK-ETHYMVDRCVE 11670
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD-RRVQATYPVRLT 3188
+ Y V T E+D +K E E P ++L V+A +RL
Sbjct: 11671 N---QIY-EFRVQTKNEGGESDW-VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLE 11725
Query: 3189 CQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL--DDGGVYEVTARNNS 3246
V G P P+V+W KD + + D + + + + T DGG Y VTA N +
Sbjct: 11726 AGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTA 11785
Query: 3247 GAVSCHCGL-VVDK 3259
G+ + + V+DK
Sbjct: 11786 GSFVAYATVNVLDK 11799
Score = 41.1 bits (92), Expect = 0.068
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL--NSF 3008
PG P V + + + W + + V+ Y +E WV+L TP+ F
Sbjct: 15847 PGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLER---KERNSILWVKLNKTPIPQTKF 15903
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTS 3038
L++G EY FRV+ N G G+ S+ S
Sbjct: 15904 KTTGLEEGVEYEFRVSAENIVGIGKPSKVS 15933
Score = 40.7 bits (91), Expect = 0.090
Identities = 25/91 (27%), Positives = 37/91 (40%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP L++ V V L C + G P P V+WY++ ++ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G + +A N +G VS C L V
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 40.7 bits (91), Expect = 0.090
Identities = 57/251 (22%), Positives = 92/251 (36%), Gaps = 27/251 (10%)
Query: 2714 ECRIR--GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
ECR+ G P + W D K + + R + G C L DSG TC+A N
Sbjct: 1677 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATN 1735
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG---NVLTD------- 2821
TD + + +S V + + + + R R H G V TD
Sbjct: 1736 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1795
Query: 2822 --------YQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+V G T + + G P +V W G+ + + R RV + G++ L +
Sbjct: 1796 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR-FRVRYD-GIHYLDI 1853
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
D ++G A + G ++ + + Q D +V+ PE V E
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF---RSVLRRAPEPRPEFHVHEPGK 1910
Query: 2933 ISFRTQGEPKP 2943
+ F Q +P
Sbjct: 1911 LQFEVQKVDRP 1921
Score = 40.7 bits (91), Expect = 0.090
Identities = 46/185 (24%), Positives = 76/185 (41%), Gaps = 20/185 (10%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLN 2655
T L D +EG++ L C V +V WY N + D+++ + +V G V+N
Sbjct: 2403 TPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVIN 2459
Query: 2656 AV-PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
SD Y V G + T+ NL V E I R +RD +V E
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSV----EKIKI----IRGLRDLTCTETQNVVFE 2507
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
+ + + W DK+I +Y+ + +L + N +D G YT A ++
Sbjct: 2508 VELSHSGI-DVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEGKYTFYAGENIT 2565
Query: 2775 TDQIT 2779
+ ++T
Sbjct: 2566 SGKLT 2570
Score = 40.7 bits (91), Expect = 0.090
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTI 3111
FV L ++ ++ G+ L+C + + VVW K+G V E+ GR+ G LTI
Sbjct: 4717 FVKTLEEEVTVVKGQPLYLSCELNKER--DVVWRKDGKIVVEKPGRIVPGVIGLMRALTI 4774
Query: 3112 KDINIDDEGRYSCEATNTH 3130
D + D G Y+ N +
Sbjct: 4775 NDADDTDAGTYTVTVENAN 4793
Score = 40.7 bits (91), Expect = 0.090
Identities = 73/320 (22%), Positives = 125/320 (39%), Gaps = 35/320 (10%)
Query: 2940 EPKPKAVPERIPGE---PCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGAR 2996
EP P PG P + + + ++++W +P+ Y +E A
Sbjct: 12980 EPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQA---VN 13036
Query: 2997 WVELGITPL--NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVD 3054
W ++ P+ + A L++G EY FRVT N+ G G+ S S + A D P++
Sbjct: 13037 WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKA---AYARD-PQYPP 13092
Query: 3055 ILPGQLKILAGETANLTCSVKGKPV-----PGVVWMKNGHEVEEEAG-RMTSQFNGFDCC 3108
P K+ ++++ S GKP P + ++ + + R N
Sbjct: 13093 APPAFPKVYDTTRSSVSLS-WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13151
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
+ + D + ++ A N G Y+ + V D+ + D + E E++ D
Sbjct: 13152 FEVTGLMEDTQYQFRVYAVNKIG----YSDPSDVPDKH-YPKDILIPPE--GELDADLRK 13204
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEI 3227
+R A +RL V G PPPK++W K + D+ + F T L
Sbjct: 13205 TLILR-------AGVTMRLYVPVKGRPPPKITWSKPNVN-LRDRIGLDIKSTDFDTFLRC 13256
Query: 3228 APTNLDDGGVYEVTARNNSG 3247
N D G Y +T N+ G
Sbjct: 13257 ENVNKYDAGKYILTLENSCG 13276
Score = 40.7 bits (91), Expect = 0.090
Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 4/102 (3%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A VLE IRG+P+P + W KD K++ L + + D G Y
Sbjct: 18224 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 2767 CKAENSVWTDQITHFVNFTGR----ESQVSPNVVTAEKTRIA 2804
K N T I V R E + VTAEK +A
Sbjct: 18284 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLA 18325
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G L++ + P VT RDGV L+ + R + + + + L T DAG Y
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAEN-LTINLKESVTADAGRYEI 20052
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVIS 3375
TA+N G +T + ++ D+ P PVVIS
Sbjct: 20053 TAANSSG--TTKAFINIVVLDRPGPP-TGPVVIS 20083
Score = 40.3 bits (90), Expect = 0.12
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 21/187 (11%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L + T E T + + V W +NGV+L++ KY + + +L + N
Sbjct: 2667 LKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIV 2726
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D + Y + G + SA L V E I + +D L + E +
Sbjct: 2727 DESVYGFRL----GRLGASARLHV----ETVKI----IKKPKDVTALENATVAFEVSVSH 2774
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT-------CKAENS 2772
+P + WF + +I +++ V +L + N +P D+G YT CKA+
Sbjct: 2775 DTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLF 2832
Query: 2773 VWTDQIT 2779
V T IT
Sbjct: 2833 VETLHIT 2839
Score = 40.3 bits (90), Expect = 0.12
Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 15/173 (8%)
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
L+D V A C++ P V WY G+++ + + + HTL + L+
Sbjct: 5705 LKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLE 5763
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA 3293
D G ++TA++ H L V + EF LE + EG + V +
Sbjct: 5764 DAGEVQLTAKD----FKTHANLFVKE-----PPVEFTKPLED-QTVEEGATAVLECEV-S 5812
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTASN 3345
+ V W+++G + S++ + DG++ +L + T D YTC A +
Sbjct: 5813 RENAKVKWFKNGTEILKSKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 40.3 bits (90), Expect = 0.12
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 3167 PPQFTMRLRDRR---VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ + R+ V+A P+RL V G P PKV+W K G + V K + D
Sbjct: 12106 PPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF 12165
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSG 3247
L I + DD G Y +T N +G
Sbjct: 12166 -LVIPNSTRDDSGKYSLTLVNPAG 12188
Score = 40.3 bits (90), Expect = 0.12
Identities = 73/313 (23%), Positives = 117/313 (37%), Gaps = 34/313 (10%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P P P V + + + W D + ++ Y VE + G RW++ L
Sbjct: 15157 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER---RDKAGQRWIKCNKKTLT 15213
Query: 3007 S--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILA 3064
+ L +G EY FR+ N G S TS +P PG ++L
Sbjct: 15214 DLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG----PPGNPRVL- 15268
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVE-----EEAGRMTSQFNGFDCC-LTIKDINID 3117
+T+ + S+ KP+ G+ VE E+ ++ + G TI + +
Sbjct: 15269 -DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTEN 15327
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
E + A N+ G + T D L E E++ D T+R
Sbjct: 15328 QEYKIRIYAMNSEGLGEP-----ALVPGTPKAEDRMLPPE--IELDADLRKVVTIR---- 15376
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
A +RL + G P P+V W +D E + DK + + L + N D G
Sbjct: 15377 ---ACCTLRLFVPIKGRPAPEVKWARDHGESL-DKASIE-STSSYTLLIVGNVNRFDSGK 15431
Query: 3238 YEVTARNNSGAVS 3250
Y +T N+SG+ S
Sbjct: 15432 YILTVENSSGSKS 15444
Score = 39.9 bits (89), Expect = 0.16
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 17/169 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E +L C ++S + WY N V L + KY G L V +
Sbjct: 2227 LQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKE 2285
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIR 2718
D EYS ++ + T+ LK+ P P + + D + E ++V LE ++
Sbjct: 2286 DQGEYSFVIDGK----KTTCKLKM------KPRPIAILQGLSDQ-KVCEGDIVQLEVKVS 2334
Query: 2719 GQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
+ + + W KD +++ PSD + + L I++ T ED+G Y+
Sbjct: 2335 LESVEGV-WMKDGQEVQPSDRVH--IVIDKQSHMLLIEDMTKEDAGNYS 2380
Score = 39.9 bits (89), Expect = 0.16
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 11/169 (6%)
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN-NSGAVSCHCGLVV 3257
++W G + ++ NK E+ L+ +L +GG YE + N+ VS V
Sbjct: 9554 LAWDPTGTKKEAWRQCNKRDVEE---LQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVG 9610
Query: 3258 DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIM- 3316
+ P L+ ++ EG + I A ++ P +TW++ + ++ ++
Sbjct: 9611 PCDCQRPDMPP-SIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY 9669
Query: 3317 -----TLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
L D L + D G+YT TA N +G AS ++ V+G
Sbjct: 9670 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9718
Score = 39.9 bits (89), Expect = 0.16
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +RI A V+ P +TW ++G L +R + D ++EL + D G Y
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLP-RVELQIKEAVRADHGKYII 11484
Query: 3342 TASNEVGRASTSGKVEVI 3359
+A N G A S V V+
Sbjct: 11485 SAKNSSGHAQGSAIVNVL 11502
Score = 39.9 bits (89), Expect = 0.16
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 2701 RDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+DT L E LE + G+P P + W KD K++ + + +AD L + T
Sbjct: 14971 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE-IKIADFSTNLVNKDSTR 15029
Query: 2760 EDSGTYTCKAEN 2771
DSG YT A N
Sbjct: 15030 RDSGAYTLTATN 15041
Score = 39.9 bits (89), Expect = 0.16
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
L G+ R+ A V P + W +DG L + + + + D L T RD+G
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGA 15034
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVV 3373
YT TA+N G A V+V+ D+ P P V
Sbjct: 15035 YTLTATNPGGFAKHIFNVKVL--DRPGPPEGPLAV 15067
Score = 39.9 bits (89), Expect = 0.16
Identities = 23/79 (29%), Positives = 38/79 (48%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A +++ + G P PKV+ +DG + R N + T+ + + D G Y
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20050
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
E+TA N+SG +VV
Sbjct: 20051 EITAANSSGTTKAFINIVV 20069
Score = 39.9 bits (89), Expect = 0.16
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
E L+ + G LR+ V P +TW + G+ L + RAI+ + L
Sbjct: 22950 ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSL-LI 23006
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ V DAG YT A N+ G+ S + V+V T
Sbjct: 23007 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDT 23040
Score = 39.9 bits (89), Expect = 0.16
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 2949 RIPGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP- 3004
RIPG P + D + ++L W + + V Y VE + A+ RWV + P
Sbjct: 23433 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD---RWVRVNKVPV 23489
Query: 3005 -LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
+ + + L +G EY RVT N G G+ S+ S I
Sbjct: 23490 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 23527
Score = 39.5 bits (88), Expect = 0.21
Identities = 15/38 (39%), Positives = 23/38 (60%)
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+P+F+ KP S + EG T + +VVG P P+ +W D
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1447
Score = 39.5 bits (88), Expect = 0.21
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 9/141 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E V C V ++ W+RN + + KY D + TL + +A
Sbjct: 6149 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207
Query: 2660 DSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D A Y+ ++ N G + ++ANL V E + ++D + + + C++
Sbjct: 6208 DQANYNVSLTNHRGENVKSAANLIV----EEEDL--RIVEPLKDIETMEKKSVTFWCKVN 6261
Query: 2719 GQPLPKITWFKDDKQIPSDGR 2739
+ + W K+ +++P D R
Sbjct: 6262 RLNV-TLKWTKNGEEVPFDNR 6281
Score = 39.5 bits (88), Expect = 0.21
Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 7/121 (5%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL 2634
E+R VI +++T+ + ++ + A G +K+ V+ PTVTW + +L
Sbjct: 14553 ESRPVIVKEQTMLPELDLRGIYQKLVI---AKAGDNIKVEIPVLGRPKPTVTWKKGDQIL 14609
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
+ + L + V SDS Y T N G + ++V+ P PP
Sbjct: 14610 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHD----IPGPP 14665
Query: 2695 T 2695
T
Sbjct: 14666 T 14666
Score = 39.5 bits (88), Expect = 0.21
Identities = 22/76 (28%), Positives = 32/76 (42%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G K+ + PT+ W + L N + K D +L V +AV DS Y
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 2668 VENENGAISTSANLKV 2683
+N G S + N+KV
Sbjct: 16121 AKNVAGERSVTVNVKV 16136
Score = 39.5 bits (88), Expect = 0.21
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
Y + G++L+I V P ++W +DG L+ + R + + L + D
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LHIKEGNKDDF 17882
Query: 3337 GVYTCTASNEVGRASTSGKVEVI 3359
G YT TA+N G A+ + V V+
Sbjct: 17883 GKYTVTATNSAGTATENLSVIVL 17905
Score = 39.5 bits (88), Expect = 0.21
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
++A +RL V G PPP ++W K G ++ R E + L + N D G Y
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDAGKY 23018
Query: 3239 EVTARNNSGAVS 3250
+ A N SG S
Sbjct: 23019 TIEAENQSGKKS 23030
Score = 39.5 bits (88), Expect = 0.21
Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 9/151 (5%)
Query: 3225 LEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-- 3280
LE T+L++G Y + A+N G + V P P +H
Sbjct: 23195 LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 23254
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
G + + + P +W+ G +LR S R +T++ ++ +L + T RD G Y
Sbjct: 23255 AGRPVELVIPIAGRPPPAASWFFAGSKLRESER--VTVETHTKVAKLTIRETTIRDTGEY 23312
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T N G +TS ++VI D+ P P
Sbjct: 23313 TLELKNVTG--TTSETIKVIILDKPGPPTGP 23341
Score = 39.5 bits (88), Expect = 0.21
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 8/152 (5%)
Query: 3281 EGDELRISAVVEAYP-SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
EG ++ +E Y S VTWY +L S + +T + DG L + +T D G Y
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGTY 25142
Query: 3340 TCTASNEVGRASTSGKVEVIGT----DQTSEPRIPPVVISPDVP--YSKEPMFIRKPRSS 3393
C N+ G S+ ++ V G D + + D + P F +
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25202
Query: 3394 EAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
A G+ V + P+P V W + K++
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIK 25234
Score = 39.1 bits (87), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+F ++D +V C+V P V W KD +E+ R +++ H L I
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIP 3071
Query: 3229 PTNLDDGGVYEVTARNN 3245
T + D G Y V A N
Sbjct: 3072 STRMSDAGKYTVVAGGN 3088
Score = 39.1 bits (87), Expect = 0.28
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L ++ G A +V G+P P V W K ++
Sbjct: 3575 PHFLKELK-PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 3633
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
+ D +D G Y C+A N G+++ A L V+ + T D K + + E D+P
Sbjct: 3634 IVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM-TDTPCKAKSTPEAPEDFP 3690
Score = 39.1 bits (87), Expect = 0.28
Identities = 75/325 (23%), Positives = 124/325 (38%), Gaps = 36/325 (11%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS--- 3007
PG+P V+ + ++W +P+ Y +E EG W + P+
Sbjct: 9105 PGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEK---REEGSPYWSRVSRAPITKVGL 9161
Query: 3008 ----FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL 3063
F+ L +G +Y FR N G G S+ S +AGD P F P ++
Sbjct: 9162 KGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP---EVAGD-PIFPPGPPSCPEVK 9217
Query: 3064 AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
++++ K G +K G+ VE + T K +N D+ +
Sbjct: 9218 DKTKSSISLGWKPPAKDGGSPIK-GYIVEMQEEGTTDW----------KRVNEPDKLITT 9266
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEAD-AKLKRERSAEVEGDYPPQFT-MRLRDRRV-Q 3180
CE + K R V E++ + E A + P F + +D V +
Sbjct: 9267 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCK 9326
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDG--EEVVYDKRRNKYQDEQFHTLE------IAPTNL 3232
A +R+ + G P PK SW DG ++ + D + +D Q T E I
Sbjct: 9327 AGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKR 9386
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVV 3257
G Y +TA+N +G + +C + V
Sbjct: 9387 SHTGKYSITAKNKAGQKTANCRVKV 9411
Score = 39.1 bits (87), Expect = 0.28
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 3167 PPQFTMRLRDRRV---QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ M ++ R V +A +++ + G P P +SW KDG E+ R +
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19348
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSG--AVSCHCGLVVDK 3259
L + D G Y +T +N +G +V+ +C V+DK
Sbjct: 19349 LLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNC-KVLDK 19385
Score = 38.7 bits (86), Expect = 0.36
Identities = 65/299 (21%), Positives = 109/299 (36%), Gaps = 40/299 (13%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDC 3107
+P FV+ L + I G + G P P +VW+KN V + ++ + +
Sbjct: 1509 KPMFVEKLKN-VNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1567
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL----KRERSAEV- 3162
L I D Y+ A N G+ +T ++ V + E + KL R+ E+
Sbjct: 1568 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1627
Query: 3163 -----------------EGD-------YPPQFTMRLRDRRVQATYPVRLTCQV--IGSPP 3196
EGD P F +L R++ P C++ IG P
Sbjct: 1628 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPT 1687
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
V W DG+ + R + + +L+ D G+ A N G L+
Sbjct: 1688 MVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Query: 3257 V--DKG-IRAYVAPEFCCGLEPLYKL----HEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
V +K + PE GL+ + +L HEG ++ + + Y + VR+
Sbjct: 1748 VKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1806
Score = 38.7 bits (86), Expect = 0.36
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRV 3023
V L W D +P+ Y VE + + + ++ +T L F +L QG+EY F+V
Sbjct: 7007 VHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDF-VTDLE-FTVPDLVQGKEYLFKV 7064
Query: 3024 TPRNRYGWGESSQTSSSIGVGLAGDRPE 3051
RN+ G GE + + + P+
Sbjct: 7065 CARNKCGPGEPAYVDEPVNMSTPATVPD 7092
Score = 38.3 bits (85), Expect = 0.48
Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 11/178 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE--VTARNNSGAV- 3249
G P K + EE D +R D+ T E NL + Y V A N +G
Sbjct: 9235 GGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESE 9294
Query: 3250 -SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
S G + I+ G + G ++RI AV++ P+ +W DG
Sbjct: 9295 PSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAK 9354
Query: 3309 RPSRRAIMTLDRDGQIELA-------LAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ + + + D Q+E A + G Y+ TA N+ G+ + + +V+V+
Sbjct: 9355 KAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVM 9412
Score = 38.3 bits (85), Expect = 0.48
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 11/125 (8%)
Query: 2947 PERIPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGIT 3003
P +P EP V + + +AW + D +P++ Y +E WV+ T
Sbjct: 12591 PFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER---KERNSLLWVKANDT 12647
Query: 3004 PLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGD---RPEFVDILPG 3058
+ S + L +G EY FR+ N+ G S+ + + + D +PE +D+
Sbjct: 12648 LVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKS 12707
Query: 3059 QLKIL 3063
+ ++
Sbjct: 12708 TVSLI 12712
Score = 38.3 bits (85), Expect = 0.48
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 7/133 (5%)
Query: 2659 SDSAEYSCTV--ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAE--NELVLE 2714
++ EY+ V ENENG T + + V + P + + D +LA+ + L+
Sbjct: 13449 TEGKEYTFRVSAENENGE-GTPSEITVVARDDVVA-PDLDLKGLPDLCYLAKENSNFRLK 13506
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
I+G+P P ++W K + + +D R A + D D+G YT +N
Sbjct: 13507 IPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYD-CQKSDAGKYTITLKNVAG 13565
Query: 2775 TDQITHFVNFTGR 2787
T + T + G+
Sbjct: 13566 TKEGTISIKVVGK 13578
Score = 38.3 bits (85), Expect = 0.48
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 8/145 (5%)
Query: 2663 EYSCTVENENGAIST-SANLKVYPSFEASPIPP-TFTRSIRDTFHLAENELV-LECRIRG 2719
E+ +N GAIS S + + + +P + RDT + E LE + G
Sbjct: 17095 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 17154
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
+PLP I W + DK+I R + D L + + D G Y +A N +
Sbjct: 17155 KPLPTIEWLRGDKEIEESARCE-IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFP 17213
Query: 2780 HFVNFTGR----ESQVSPNVVTAEK 2800
V R E V VT+EK
Sbjct: 17214 VNVKVLDRPGPPEGPVQVTGVTSEK 17238
Score = 37.9 bits (84), Expect = 0.64
Identities = 42/166 (25%), Positives = 76/166 (45%), Gaps = 20/166 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV---DGLIT 2650
P F+ L D T VE V L C IS +D V W+++G ++K K V DG
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCE-ISKADAPVKWFKDG----KEIKPSKNAVIKADGKKR 5575
Query: 2651 LEVL-NAVPSDSAEYSCT--VENENGAIS-TSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
+ +L A+ SD +Y+C + +G + +K+ + + T T R +
Sbjct: 5576 MLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETET--ARFETEI 5633
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
+E+++ +++G+ L + D +I +G+ + L + CRL
Sbjct: 5634 SEDDIHANWKLKGEALLQ----TPDCEIKEEGKIHSLVLHN--CRL 5673
Score = 37.9 bits (84), Expect = 0.64
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 3278 KLHEGDELRISAVVEAYPSVGVTWYRDGVRL-RPSRRAIMTLDR----DGQIELALAAVT 3332
K+ G+ + I A V P + W ++ + +P+ +T + + + EL++
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPR 3368
D G YT TASN +G + VEV D+ S PR
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVY--DRPSPPR 9005
Score = 37.9 bits (84), Expect = 0.64
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
R++ ++ +RL+ + G P PKV+W K+ + R + LEI +D
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARID--VTPVGSKLEIRNAAHED 10786
Query: 3235 GGVYEVTARNNSGAVSCHCG-LVVDK 3259
GG+Y +T N +G+ + LV+DK
Sbjct: 10787 GGIYSLTVENPAGSKTVSVKVLVLDK 10812
Score = 37.9 bits (84), Expect = 0.64
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKL-KYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G ++L V P VTW + G+ DN + K + LVD + L + N+ DS +YS
Sbjct: 12124 GCPIRLFAIVRGRPAPKVTWRKVGI--DNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSL 12181
Query: 2667 TVENENGAISTSANLKV 2683
T+ N G + N++V
Sbjct: 12182 TLVNPAGEKAVFVNVRV 12198
Score = 37.9 bits (84), Expect = 0.64
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 7/97 (7%)
Query: 2677 TSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS 2736
T L + P + S IP + T + N + LE +G+P P I+W KD +
Sbjct: 21056 TVKELIITPEVDLSDIP-----GAQVTVRIGHN-VHLELPYKGKPKPSISWLKDGLPL-K 21108
Query: 2737 DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ + F + L+I N E G YT +N+V
Sbjct: 21109 ESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV 21145
Score = 37.5 bits (83), Expect = 0.84
Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ L+I+A + P ++W +DG+ + R + + D L + RD G Y
Sbjct: 19307 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIRRDTGQYVL 19365
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T N G S + +V+ D+ P P
Sbjct: 19366 TLKNVAGTRSVAVNCKVL--DKPGPPAGP 19392
Score = 37.1 bits (82), Expect = 1.1
Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
P+F L DY + LQ EI V+W ++G+ + + +NA + + L L
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEI-KPSKNAVIKADGKKRMLIL 5579
Query: 2873 SDVTETESGLYTCRAWS--AHGNVDM-NAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
+++ G YTC + G +D+ + I +V+P R E +I +
Sbjct: 5580 KKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEI---SED 5636
Query: 2930 DINISFRTQGE 2940
DI+ +++ +GE
Sbjct: 5637 DIHANWKLKGE 5647
Score = 37.1 bits (82), Expect = 1.1
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW--VELGITPLNSF 3008
PG P V + ++++W + +P+L Y VE G W V + P N F
Sbjct: 14765 PGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVER---KERNGILWQTVSKALVPGNIF 14821
Query: 3009 DAFNLKQGEEYHFRVTPRNRYGWGESSQTS 3038
+ L G Y FRV N G + S+ S
Sbjct: 14822 KSSGLTDGIAYEFRVIAENMAGKSKPSKPS 14851
Score = 37.1 bits (82), Expect = 1.1
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL--VDGLITL 2651
P +D + EG + + C+ P VTW G + ++ + R + D L TL
Sbjct: 26832 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 26891
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+++ D Y+ ++ NE G+ S + N+ +
Sbjct: 26892 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 36.7 bits (81), Expect = 1.5
Identities = 23/79 (29%), Positives = 32/79 (40%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A VR + G P P W DG E+ D+ D L I D G Y
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
++T N +G+ + L V
Sbjct: 11085 QITVSNAAGSKTVAVHLTV 11103
Score = 36.7 bits (81), Expect = 1.5
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 3167 PPQFTMRLRDRRV---QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH 3223
PP+ + R+V +A+ +RL + G P P+V W K E ++ D+ + + F
Sbjct: 18607 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEV-TSSFT 18664
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGA 3248
L I D G Y +T NNSG+
Sbjct: 18665 MLVIDNVTRFDSGRYNLTLENNSGS 18689
Score = 36.7 bits (81), Expect = 1.5
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 7/125 (5%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A L L I+G+P P++ W K + + + + + L IDN T DSG Y
Sbjct: 18624 ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIE---VTSSFTMLVIDNVTRFDSGRYN 18680
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHF--GNVLTDYQV 2824
EN+ + T FVN +S +P +T + + +L P G +T+Y V
Sbjct: 18681 LTLENN--SGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIV 18738
Query: 2825 ARGGT 2829
+ T
Sbjct: 18739 EKRET 18743
Score = 36.7 bits (81), Expect = 1.5
Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ ++L SV P +TW + G+ L ++ L+ ++ +N D+ +Y+
Sbjct: 22964 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY--DAGKYTIE 23021
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSI-RDT 2703
EN++G S + +KVY + P P + + RD+
Sbjct: 23022 AENQSGKKSATVLVKVYDT--PGPCPSVKVKEVSRDS 23056
Score = 36.3 bits (80), Expect = 1.9
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 3049 RPEFVDILPG--QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
+P + IL G K+ G+ L V + V GV WMK+G EV + + R+ +
Sbjct: 2306 KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEV-QPSDRVHIVIDKQS 2363
Query: 3107 CCLTIKDINIDDEGRYS----CEATNTHGKASTYA 3137
L I+D+ +D G YS +T G+ S Y+
Sbjct: 2364 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS 2398
Score = 36.3 bits (80), Expect = 1.9
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EFV+ L Q + + A +C + + V W +NG E++E + + +G L
Sbjct: 6327 EFVEHLEDQT-VTEFDDAVFSCQLSREKA-NVKWYRNGREIKE-GKKYKFEKDGSIHRLI 6383
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTY 3136
IKD +DDE Y+C + +A +
Sbjct: 6384 IKDCRLDDECEYACGVEDRKSRARLF 6409
Score = 36.3 bits (80), Expect = 1.9
Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
R++G+P P ITW K+ K + + R V L I D G Y A+NS
Sbjct: 11434 RVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADHGKYIISAKNSSGH 11492
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Q + VN R VT S E+ + G+ +T++ V
Sbjct: 11493 AQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11541
Score = 36.3 bits (80), Expect = 1.9
Identities = 46/162 (28%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 2653 VLNAVPSDSAEYSCTVENENGAIS----TSANLKVYPSFEASPIPPTFTRSIRDTFHL-A 2707
V + V E+ +N GAIS ++ + +EA I +I+D + A
Sbjct: 13838 VTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTI--VLDPTIKDGLTIKA 13895
Query: 2708 ENELVLEC-RIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ +VL I G+PLPK +W K K I PSD L I T +D+G Y
Sbjct: 13896 GDTIVLNAISILGKPLPKSSWSKAGKDIRPSD--ITQITSTPTSSMLTIKYATRKDAGEY 13953
Query: 2766 TCKAENSVWTDQITH----FVNFTGRESQVSPNVVTAEKTRI 2803
T A N T ++ H ++ G V + V+AEK +
Sbjct: 13954 TITATNPFGT-KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 13994
Score = 36.3 bits (80), Expect = 1.9
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVV-YDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
RL V G PPP + W KDG+E+ K K D + + T D G Y +TA N
Sbjct: 14983 RLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDSGAYTLTATN 15041
Query: 3245 NSG 3247
G
Sbjct: 15042 PGG 15044
Score = 36.3 bits (80), Expect = 1.9
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A +L +E + G+P P I+W KD + + R A L I +D G YT
Sbjct: 17828 AGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LHIKEGNKDDFGKYT 17886
Query: 2767 CKAENSVWT 2775
A NS T
Sbjct: 17887 VTATNSAGT 17895
Score = 36.3 bits (80), Expect = 1.9
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 9/123 (7%)
Query: 2662 AEYSCTVENEN--GAI--STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
AEY V++ N GA S S++ ++ E P+ + + A +
Sbjct: 19654 AEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPF 19713
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFY-LADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
RG+P+P + W K D +D R +A+ D L I+N DSG YT +N +
Sbjct: 19714 RGRPVPNVLWSKPD----TDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19769
Query: 2777 QIT 2779
+T
Sbjct: 19770 SLT 19772
Score = 36.3 bits (80), Expect = 1.9
Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
D P ++T ++ R A V+L + G P P + WYKD +E+ + +
Sbjct: 20376 DLPLEYTEVVKYR---AGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20432
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVS 3250
+ I + + G YE+ RN G+ S
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGSAS 20458
Score = 36.3 bits (80), Expect = 1.9
Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 8/113 (7%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+P +T ++ + A + L I G+P P I W+KDDK++ ++ D +
Sbjct: 20377 LPLEYTEVVK---YRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LAS 20432
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVVTAEK 2800
+ I + +SG Y K N++ + T V + + VTAEK
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEK 20485
Score = 35.9 bits (79), Expect = 2.6
Identities = 37/168 (22%), Positives = 59/168 (35%), Gaps = 3/168 (1%)
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTF--TRSIRDTFHLAENELVLECRIRGQP 2721
Y N GA S + + + P F + + A ++ L + G+P
Sbjct: 7162 YRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7221
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PKITW K D + D R + +D+ D+GTY +A N
Sbjct: 7222 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR-SDTGTYIIEAVNVCGRATAVVE 7280
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
VN + + +T + R G+ +T+Y V R T
Sbjct: 7281 VNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRAT 7328
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/76 (27%), Positives = 31/76 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L V PT+ W ++G L+ K K+ D L ++ DS Y+ T
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 2668 VENENGAISTSANLKV 2683
N G N+KV
Sbjct: 15039 ATNPGGFAKHIFNVKV 15054
Score = 35.9 bits (79), Expect = 2.6
Identities = 24/102 (23%), Positives = 38/102 (37%), Gaps = 4/102 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F T + G +K+ I P VTW+++ V L + + + L +
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15710
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPT 2695
+A D Y + N G + N+ V P PPT
Sbjct: 15711 KDACREDVGHYVVKLTNSAGEAIETLNVIVLD----KPGPPT 15748
Score = 35.9 bits (79), Expect = 2.6
Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 3/83 (3%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQ 3015
V D + V+L W + + + Y VE AE RW+ +G + NL
Sbjct: 24633 VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAE---RWLRVGQARETRYTVINLFG 24689
Query: 3016 GEEYHFRVTPRNRYGWGESSQTS 3038
Y FRV N++G + S+ S
Sbjct: 24690 KTSYQFRVIAENKFGLSKPSEPS 24712
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPS--DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
L + C G+P P++TW ++I S GR+ D + L I + +D G YT
Sbjct: 26849 LTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFH-IENTDDLTTLIIMDVQKQDGGLYTLS 26907
Query: 2769 AENSVWTDQIT 2779
N +D T
Sbjct: 26908 LGNEFGSDSAT 26918
Score = 35.5 bits (78), Expect = 3.4
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERS 3159
+G D KD I +Y EA HGK L ++ D + + A + +
Sbjct: 2513 SGIDVLWNFKDKEIKPSSKYKIEA---HGKIYKLTVLNMMKDDEGKYTFYAGENITSGKL 2569
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
G + L D+ V + C+V +P K W +DG+ + D
Sbjct: 2570 TVAGG----AISKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESD 2624
Query: 3220 EQFHTLEIAPTNLDDGGVY 3238
L IA T LDD G Y
Sbjct: 2625 GHKRRLIIAATKLDDIGEY 2643
Score = 35.5 bits (78), Expect = 3.4
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 2678 SANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD 2737
+AN K + + +P F + D ++E EC + +P W K ++I D
Sbjct: 5327 AANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGD 5385
Query: 2738 GRYQAFYLADGVCR-LAIDNPTPEDSGTYTCKAEN 2771
R++ + DG + I + ED Y +AE+
Sbjct: 5386 DRFE--LIKDGTKHSMVIKSAAFEDEAKYMFEAED 5418
Score = 35.5 bits (78), Expect = 3.4
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPI--PPTFTRSIRDTFHLAENELVLECRI 2717
+ EY V EN A + + P+ PI P R+ + +E+ L+ I
Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKR--GDEIALDASI 8206
Query: 2718 RGQPLPKITWFKDDKQI 2734
G P P ITW KD+ I
Sbjct: 8207 SGSPYPTITWIKDENVI 8223
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+RG+P PK+TW K I + R L D + L I N T +DSG Y+ N
Sbjct: 12133 VRGRPAPKVTWRK--VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVN 12185
Score = 35.5 bits (78), Expect = 3.4
Identities = 30/126 (23%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 3238 YEVTARNNSGAVSCHCGLVVD-KGIRAYVAPEFCCGLE--PLYKLHEGDELRISAVVEAY 3294
+ V ARN G++S +V I +Y P LE + K G +++ A +
Sbjct: 20343 FRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 20402
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASNEVGRASTS 3353
P+ + WY+D L+ + A++ ++ + L R ++G Y N +G AS +
Sbjct: 20403 PAPTIEWYKDDKELQTN--ALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT 20460
Query: 3354 GKVEVI 3359
+V+++
Sbjct: 20461 IRVQIL 20466
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ +G +R++ ++ P W ++G + S+RA++ + EL + D+G
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATS-ETHTELVIKEADRGDSGT 23707
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSE 3366
Y N+ G+ + KV VIG+ + E
Sbjct: 23708 YDLVLENKCGKKAVYIKVRVIGSPNSPE 23735
Score = 35.5 bits (78), Expect = 3.4
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+RLT + G P P W K+G+++ KR E L I + D G Y++ N
Sbjct: 23657 IRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 23714
Query: 3245 NSG 3247
G
Sbjct: 23715 KCG 23717
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+ KPRS EG++ C+ G+P P V WLR
Sbjct: 26067 LTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + + G + EI G P+ +EW + ++ + N + + +Y
Sbjct: 26634 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS-ISSNVSISRSRNVY 26692
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L + + + ++SG YT +A + G A++ V+
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
T R+P V P P P + ++ EG++V +EC + G P P V W R+
Sbjct: 881 TETARVPAPVEIPVTP----PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRE 933
Score = 35.1 bits (77), Expect = 4.5
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 8/106 (7%)
Query: 2950 IPGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
+PG P + D VSL W + A + Y +E + + RW
Sbjct: 6693 VPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIE---LRDKTSIRWDTAMTVRAE 6749
Query: 3007 SFDAF--NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP 3050
A ++ +G+EY FRV +NR G G+ S + + V +RP
Sbjct: 6750 DLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 6795
Score = 35.1 bits (77), Expect = 4.5
Identities = 21/69 (30%), Positives = 30/69 (43%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
V+A + L V G P PK++W K + DKR + T+ I + D G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264
Query: 3239 EVTARNNSG 3247
+ A N G
Sbjct: 7265 IIEAVNVCG 7273
Score = 35.1 bits (77), Expect = 4.5
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 2997 WVELGIT-PLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
W ++ T P+ S L +G EY FR+ N+YG G+ T +I
Sbjct: 12938 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAI 12983
Score = 35.1 bits (77), Expect = 4.5
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A L L I+G+P P++ W K D +I + L +DN DSG YT
Sbjct: 16459 AGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIID---VTSSFTSLVLDNVNRYDSGKYT 16515
Query: 2767 CKAENSVWT 2775
ENS T
Sbjct: 16516 LTLENSSGT 16524
Score = 35.1 bits (77), Expect = 4.5
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KP FS++ + G +K+ + PT+TW ++G+ L + L TL
Sbjct: 16736 KPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLS 16791
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL 2681
+ D +Y TV N G + S +
Sbjct: 16792 IKETHKDDGGQYGITVANVVGQKTASIEI 16820
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/55 (32%), Positives = 25/55 (45%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
G PPP V+W KD + + D R + + L I +D G Y +T N G
Sbjct: 20800 GRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854
Score = 34.7 bits (76), Expect = 5.9
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 7/135 (5%)
Query: 3230 TNLDDGG--VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL--HEGDEL 3285
T L++G Y V A N GA + + APE ++ L L G ++
Sbjct: 7152 TGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7211
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTAS 3344
+ A V P +TW + + L+ +R +T++ + + R D G Y A
Sbjct: 7212 ELPATVTGKPEPKITWTKADMILKQDKR--ITIENVPKKSTVTIVDSKRSDTGTYIIEAV 7269
Query: 3345 NEVGRASTSGKVEVI 3359
N GRA+ +V V+
Sbjct: 7270 NVCGRATAVVEVNVL 7284
Score = 34.7 bits (76), Expect = 5.9
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYT 3340
G LRI AVV P W ++ L R + +D G + EL + +D G Y
Sbjct: 8622 GKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKDHGRYV 8678
Query: 3341 CTASNEVGRASTSGKVEV 3358
TA+N G + +VEV
Sbjct: 8679 ITATNSCGSKFAAARVEV 8696
Score = 34.7 bits (76), Expect = 5.9
Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 2951 PGEPC---VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN- 3006
PG P V D L+W + APV Y +E + WV +
Sbjct: 19781 PGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKA---WVSVTNNCNRL 19837
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE 3051
S+ NL++G Y+FRV+ N +G G ++T + + PE
Sbjct: 19838 SYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 19882
Score = 34.7 bits (76), Expect = 5.9
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +++ V P VTW+++GV ++ ++ V G +L V +A Y T
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY--T 21533
Query: 2668 VENENGAISTSANLKV 2683
VE +N + S A +KV
Sbjct: 21534 VEAKNASGSAKAEIKV 21549
Score = 34.7 bits (76), Expect = 5.9
Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 4/131 (3%)
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + ++ I G+P PK+TW ++ ++ R D L + + DSG Y
Sbjct: 22164 AGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRT-TLTVKDSMRGDSGRYF 22222
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVS-PNVVTAEKTRIARQSLESRRPHFGNVLTDYQVA 2825
EN+ + V GR V+ P V++ S + G +T+Y V
Sbjct: 22223 LTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVE 22282
Query: 2826 R--GGTIGLQV 2834
+ GT Q+
Sbjct: 22283 KRESGTTAWQL 22293
Score = 34.7 bits (76), Expect = 5.9
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G I + P+ VTW + +RL+ + R +T +D + L + D+G Y
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKD-RTTLTVKDSMRGDSGRYFL 22223
Query: 3342 TASNEVGRASTSGKVEVIG 3360
T N G + S V VIG
Sbjct: 22224 TLENTAGVKTFSVTVVVIG 22242
Score = 34.7 bits (76), Expect = 5.9
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K E +G + P+ DVP + P F + R+ R + C+V G PKP
Sbjct: 24403 KCENLGGESEWSEISEPITPKSDVPI-QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 24461
Query: 3415 VYWLR 3419
V W R
Sbjct: 24462 VKWYR 24466
Score = 34.3 bits (75), Expect = 7.9
Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 15/85 (17%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVE-------SWLIGAEGGARWVELGITPLNSFDAFNLKQG 3016
VSLAW + + ++ Y VE +W++ + A E +T L K G
Sbjct: 6609 VSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDR-AESCEFTVTGLQ-------KGG 6660
Query: 3017 EEYHFRVTPRNRYGWGESSQTSSSI 3041
EY FRV+ RNR G GE +T + +
Sbjct: 6661 VEYLFRVSARNRVGTGEPVETDNPV 6685
Score = 34.3 bits (75), Expect = 7.9
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 3/81 (3%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV-CRL 2752
PT D + +L + R P+P ++W KD K++ + R D + L
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT--MKNDHISAHL 7947
Query: 2753 AIDNPTPEDSGTYTCKAENSV 2773
+ D+G YT EN +
Sbjct: 7948 EVPKSVRADAGIYTITLENKL 7968
Score = 34.3 bits (75), Expect = 7.9
Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+G+P P+ITW +++ + + + +L+IDN D+G Y K ENS
Sbjct: 17552 KGRPTPEITWSREEGEFTDKVQIEK---GVNYTQLSIDNCDRNDAGKYILKLENS 17603
>AY358330-1|AAQ88696.1| 477|Homo sapiens papilin protein.
Length = 477
Score = 90.6 bits (215), Expect = 9e-17
Identities = 101/358 (28%), Positives = 151/358 (42%), Gaps = 53/358 (14%)
Query: 3037 TSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG 3096
TS + LAG P V GQL L+CS P W K+G + +
Sbjct: 102 TSHLSRISLAGVEPSLVQAALGQL-------VRLSCSDDTAPESQAAWQKDGQPISSDRH 154
Query: 3097 RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKR 3156
R+ QF+G L I + +D G YSC +T G+ S +L ++ ++A+L R
Sbjct: 155 RL--QFDG---SLIIHPLQAEDAGTYSCGSTRP-GRDSQKIQLRIIGGDMAVLSEAELSR 208
Query: 3157 -------------ERSAEVEGDYP---PQFTMRLR----DRRVQATYP---VRLTCQVIG 3193
+A G P PQ RLR RV P +R+TC+ G
Sbjct: 209 FPQPRDPAQDFGQAGAAGPLGAIPSSHPQPANRLRLDQNQPRVVDASPGQRIRMTCRAEG 268
Query: 3194 SPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHC 3253
PPP + W +DG+ V R++ Q + +L I+ ++DGG Y A N
Sbjct: 269 FPPPAIEWQRDGQPV--SSPRHQLQPD--GSLVISRVAVEDGGFYTCVAFNGQDR----- 319
Query: 3254 GLVVDKGIRAYVAPEF-CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
+ ++ V E GL P + EGD R+ VV A SV + W R+G+ ++
Sbjct: 320 ---DQRWVQLRVLGELTISGLPPTVTVPEGDTARLLCVV-AGESVNIRWSRNGLPVQADG 375
Query: 3313 RAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+ DG L + + RD G Y C+A S S +V+V+ T++PR P
Sbjct: 376 HRVHQ-SPDG--TLLIYNLRARDEGSYMCSAYQGSQAVSRSTEVKVVSPAPTAQPRDP 430
Score = 49.2 bits (112), Expect = 3e-04
Identities = 44/166 (26%), Positives = 67/166 (40%), Gaps = 17/166 (10%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAE 2663
A G R+++TC P + W R+G + + R +L DG +L + D
Sbjct: 254 ASPGQRIRMTCRAEGFPPPAIEWQRDGQPVSSP---RHQLQPDG--SLVISRVAVEDGGF 308
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C N L+V S +PPT T DT L C + G+ +
Sbjct: 309 YTCVAFNGQDRDQRWVQLRVLGELTISGLPPTVTVPEGDTARLL-------CVVAGESV- 360
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
I W ++ + +DG ++ DG L I N D G+Y C A
Sbjct: 361 NIRWSRNGLPVQADG-HRVHQSPDGT--LLIYNLRARDEGSYMCSA 403
Score = 44.8 bits (101), Expect = 0.006
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 7/96 (7%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R++ E +P + W RDG + R L DG L ++ V D G YTC
Sbjct: 257 GQRIRMTCRAEGFPPPAIEWQRDGQPVSSPRH---QLQPDG--SLVISRVAVEDGGFYTC 311
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
A N R ++ V+G + + +PP V P+
Sbjct: 312 VAFNGQDRDQRWVQLRVLG--ELTISGLPPTVTVPE 345
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE 3093
SS + + L ++P VD PGQ +TC +G P P + W ++G V
Sbjct: 233 SSHPQPANRLRLDQNQPRVVDASPGQ-------RIRMTCRAEGFPPPAIEWQRDGQPVSS 285
Query: 3094 EAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
++ D L I + ++D G Y+C A N + + +L V+ + T+
Sbjct: 286 PRHQLQP-----DGSLVISRVAVEDGGFYTCVAFNGQDRDQRWVQLRVLGELTI 334
Score = 43.6 bits (98), Expect = 0.013
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG +L C V++ + W RNG+ + + DG TL + N D
Sbjct: 342 TVPEGDTARLLC-VVAGESVNIRWSRNGLPVQADGHRVHQSPDG--TLLIYNLRARDEGS 398
Query: 2664 YSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
Y C+ + A+S S +KV P+ A P P R D LA +L+L+ ++ G
Sbjct: 399 YMCSAYQGSQAVSRSTEVKVVSPAPTAQPRDP--GRDCVDQPELANCDLILQAQLCG 453
Score = 36.7 bits (81), Expect = 1.5
Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ CR G P P I W +D + + S R+Q DG L I ED G YTC A N
Sbjct: 262 MTCRAEGFPPPAIEWQRDGQPVSSP-RHQL--QPDG--SLVISRVAVEDGGFYTCVAFNG 316
Query: 2773 VWTDQ 2777
DQ
Sbjct: 317 QDRDQ 321
Score = 35.9 bits (79), Expect = 2.6
Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 8/105 (7%)
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
P +EW R+G+ V+ + G +L +S V + G YTC A++
Sbjct: 271 PPAIEWQRDGQPVSSPRHQLQ---PDG--SLVISRVAVEDGGFYTCVAFNGQDRDQRWVQ 325
Query: 2900 ITVVQPSDLDGKPAVIV---GRPEKDILISVGEDINISFRTQGEP 2941
+ V+ + G P + G + + + GE +NI + G P
Sbjct: 326 LRVLGELTISGLPPTVTVPEGDTARLLCVVAGESVNIRWSRNGLP 370
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
molecule 2 protein.
Length = 2113
Score = 89.8 bits (213), Expect = 1e-16
Identities = 104/408 (25%), Positives = 160/408 (39%), Gaps = 66/408 (16%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPG--QLKILAGETANLTCSVKGKP 3078
+R +++Y GE+ Q S+ + + IL G ++ AG T L C+ G P
Sbjct: 256 YRCITKHKYS-GETRQ-SNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYP 313
Query: 3079 VPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYAR 3138
+P + W+K+G + ++ R T + G LTI D+ +D G Y CE TNT G A
Sbjct: 314 IPAIRWLKDGRPLPADS-RWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGI 368
Query: 3139 LAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
L V+ V KLK + +T V L+C + GSP
Sbjct: 369 LMVIDPLHVTLTPKKLK---------------------TGIGST--VILSCALTGSPEFT 405
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
+ WY++ E V+ D+ + + TL I G Y+ A + + ++
Sbjct: 406 IRWYRNTELVLPDEAIS-IRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALE 464
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG---VRLRPSRRAI 3315
G V+ F E + ++ G++ + + P VTW D VR R
Sbjct: 465 DGTPRIVS-SFS---EKV--VNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 518
Query: 3316 MTLDRDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVI 3374
T+ I + + RD GVY CTA N VG A ++ V G
Sbjct: 519 YTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------------- 564
Query: 3375 SPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
P IR R+ A G +I C V+G P + W +D L
Sbjct: 565 ---------PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL 603
Score = 66.9 bits (156), Expect = 1e-09
Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V L+C++ S + T+ WYRN VL D + R + TL + +A S S Y
Sbjct: 389 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---TLLITSAQKSHSGAYQ 445
Query: 2666 CTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
C + T+ + + + +P I +F+ + + + L C +G P P
Sbjct: 446 CFATRK---AQTAQDFAIIALEDGTPRIVSSFSEKVVN----PGEQFSLMCAAKGAPPPT 498
Query: 2725 ITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
+TW DD+ I DG R + ++DG + + + P D G Y C A N V + +
Sbjct: 499 VTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA 558
Query: 2781 FVNFTGRESQVSPNVVTA 2798
+N G S + +TA
Sbjct: 559 RINVRGPPSIRAMRNITA 576
Score = 64.9 bits (151), Expect = 5e-09
Identities = 78/299 (26%), Positives = 117/299 (39%), Gaps = 42/299 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCC 3108
P V + P +LK G T L+C++ G P + W +N V +EA + N
Sbjct: 374 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---T 430
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I G Y C AT KA T A++ +E D P
Sbjct: 431 LLITSAQKSHSGAYQCFATR---KAQTAQDFAIIA------------------LE-DGTP 468
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD--KRRNKYQDEQFHT-- 3224
+ ++ V L C G+PPP V+W D E +V D R N+Y T
Sbjct: 469 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 528
Query: 3225 -LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGD 3283
+ + + DGGVY TARN G+ + V +G P + + + D
Sbjct: 529 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV-RG------PPSIRAMRNITAVAGRD 581
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
L I+ V YP + WY+D + L + R ++ +G ++L D G Y C+
Sbjct: 582 TL-INCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCS 636
Score = 61.7 bits (143), Expect = 5e-08
Identities = 88/381 (23%), Positives = 154/381 (40%), Gaps = 61/381 (16%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP---TVTWYRNGVLLDNKLKYRKKLVDGL 2648
R+P ++ + D+ ++ G+ C + SS V+W ++ V + + ++ GL
Sbjct: 184 REP-YTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGGL 242
Query: 2649 ITLEVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
+V + Y C +++ +G S ++ + A IP +I D FH
Sbjct: 243 YISDVQKE--DALSTYRCITKHKYSGETRQSNGARLSVTDPAESIP-----TILDGFHSQ 295
Query: 2708 E----NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
E + + L C G P+P I W KD + +P+D R+ + L I + EDSG
Sbjct: 296 EVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRW-----TKRITGLTISDLRTEDSG 350
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TY C+ N+ + + TG + P VT ++ +
Sbjct: 351 TYICEVTNTFGSAEA------TGILMVIDPLHVTLTPKKL-------------------K 385
Query: 2824 VARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTETES 2880
G T+ L + G P + W R TE+ +GL TL ++ ++ S
Sbjct: 386 TGIGSTVILSCALTGSPEFTIRWYRN----TELVLPDEAISIRGLSNETLLITSAQKSHS 441
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
G Y C A + + AI ++ DG P ++ EK +++ GE ++ +G
Sbjct: 442 GAYQCFA-TRKAQTAQDFAIIALE----DGTPRIVSSFSEK--VVNPGEQFSLMCAAKGA 494
Query: 2941 PKPKAVPERIPGEPCVVDGGN 2961
P P V + EP V DG +
Sbjct: 495 P-PPTVTWALDDEPIVRDGSH 514
Score = 59.3 bits (137), Expect = 2e-07
Identities = 81/363 (22%), Positives = 139/363 (38%), Gaps = 49/363 (13%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLE 2652
+ S+F +++ G + L C+ + PTVTW + ++ D + + + T+
Sbjct: 470 IVSSF-SEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 528
Query: 2653 VLNAV-PS--DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+N P D Y CT N G+ A + V PP+ R++R+ +A
Sbjct: 529 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------PPSI-RAMRNITAVAGR 580
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ ++ CR+ G P I W+KD +P + R F +G +L D D G Y C
Sbjct: 581 DTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCSV 637
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
+ +S +V A K Q E G +L V G
Sbjct: 638 --------------LIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGD 683
Query: 2830 IGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
+ P R+ W ++G+ + + ++ + +L +S V+ +G YTC A +
Sbjct: 684 M---------PIRITWRKDGQVIIS-GSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 733
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A V + V P P +V +D + +N S G P PK + +
Sbjct: 734 AAATVSRERQLIVRVP------PRFVVQPNNQDGIYGKAGVLNCS--VDGYPPPKVMWKH 785
Query: 2950 IPG 2952
G
Sbjct: 786 AKG 788
Score = 49.6 bits (113), Expect = 2e-04
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 19/205 (9%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
AR+++ +R + R P + + TAV G + C VI ++ WY++ +LL
Sbjct: 547 ARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLP 606
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV-ENENGAISTSAN--LKVYPSFEASP 2691
+ +++V TL++ + D EY C+V +IS S + +KV P +
Sbjct: 607 DN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFE 663
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVC 2750
PP + L + C + +P +ITW KD + I S G + +
Sbjct: 664 FPPASIGQL----------LYIPCVVSSGDMPIRITWRKDGQVIIS-GSGVTIESKEFMS 712
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWT 2775
L I + + + +G YTC A N+ T
Sbjct: 713 SLQISSVSLKHNGNYTCIASNAAAT 737
Score = 48.4 bits (110), Expect = 5e-04
Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 14/175 (8%)
Query: 2608 GSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G + + C V S P +TW ++G ++ + + + + +L++ + + Y+C
Sbjct: 670 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTC 729
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
N +S L V +PP F + + VL C + G P PK+
Sbjct: 730 IASNAAATVSRERQLIVR-------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVM 782
Query: 2727 WFKDDKQIPSDGRYQAFYLADGV-----CRLAIDNPTPEDSGTYTCKAENSVWTD 2776
W K K + +Y L + L I + ED G Y C+A N V TD
Sbjct: 783 W-KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTD 836
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
+L +G++Y V G G SS+ + + AG P + G + + L
Sbjct: 1314 HLNRGQQYLLWVAAVTSAGRGNSSE---KVTIEPAGKAPAKIISFGGTVTTPWMKDVRLP 1370
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C+ G P P V W K+ + + + L ++ + +D G Y+C ATNT G
Sbjct: 1371 CNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGG 1430
Query: 3132 KASTYARLAV 3141
+ L V
Sbjct: 1431 FDTIIVNLLV 1440
Score = 45.2 bits (102), Expect = 0.004
Identities = 43/160 (26%), Positives = 63/160 (39%), Gaps = 11/160 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCH 3252
G P +++W KDG+ ++ E +L+I+ +L G Y A N + VS
Sbjct: 682 GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRE 741
Query: 3253 CGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
L+V R V P + +Y G ++ V+ YP V W P +
Sbjct: 742 RQLIVRVPPRFVVQPN---NQDGIY----GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 794
Query: 3313 RAIMTLDRDGQI----ELALAAVTTRDAGVYTCTASNEVG 3348
+ L QI L + V D G Y C ASN VG
Sbjct: 795 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 834
Score = 39.9 bits (89), Expect = 0.16
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLEIAPTNLDDGGVYEVTAR 3243
VRL C +G P P V W KD E+ + ++ + TL + +D G Y TA
Sbjct: 1367 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1426
Query: 3244 NNSG 3247
N G
Sbjct: 1427 NTGG 1430
Score = 38.3 bits (85), Expect = 0.48
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 25/138 (18%)
Query: 3065 GETANLTCSVKGKPVP-GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G+ + C V +P + W K+G + +G +T + F L I +++ G Y+
Sbjct: 670 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSG-VTIESKEFMSSLQISSVSLKHNGNYT 728
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C A+N A A + RER V PP+F ++ ++
Sbjct: 729 CIASN---------------------AAATVSRERQLIVR--VPPRFVVQPNNQDGIYGK 765
Query: 3184 PVRLTCQVIGSPPPKVSW 3201
L C V G PPPKV W
Sbjct: 766 AGVLNCSVDGYPPPKVMW 783
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK---NGHEVEEEAGRMTSQFNGF- 3105
P FV + P + G+ L CSV G P P V+W +G+ + +T +
Sbjct: 750 PRFV-VQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILP 808
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHG 3131
+ L I+ + +D G Y C+A+N G
Sbjct: 809 NSSLLIRHVLEEDIGYYLCQASNGVG 834
Score = 35.1 bits (77), Expect = 4.5
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Query: 2713 LECRIRGQPLPKITWFKD--DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C G P P + W KD D IP +G L + EDSG YTC A
Sbjct: 1369 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT--LLLRAVKAEDSGYYTCTAT 1426
Query: 2771 NSVWTDQI 2778
N+ D I
Sbjct: 1427 NTGGFDTI 1434
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule DSCAML1 protein.
Length = 2053
Score = 89.8 bits (213), Expect = 1e-16
Identities = 104/408 (25%), Positives = 160/408 (39%), Gaps = 66/408 (16%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPG--QLKILAGETANLTCSVKGKP 3078
+R +++Y GE+ Q S+ + + IL G ++ AG T L C+ G P
Sbjct: 196 YRCITKHKYS-GETRQ-SNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYP 253
Query: 3079 VPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYAR 3138
+P + W+K+G + ++ R T + G LTI D+ +D G Y CE TNT G A
Sbjct: 254 IPAIRWLKDGRPLPADS-RWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGI 308
Query: 3139 LAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
L V+ V KLK + +T V L+C + GSP
Sbjct: 309 LMVIDPLHVTLTPKKLK---------------------TGIGST--VILSCALTGSPEFT 345
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
+ WY++ E V+ D+ + + TL I G Y+ A + + ++
Sbjct: 346 IRWYRNTELVLPDEAIS-IRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALE 404
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG---VRLRPSRRAI 3315
G V+ F E + ++ G++ + + P VTW D VR R
Sbjct: 405 DGTPRIVS-SFS---EKV--VNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 458
Query: 3316 MTLDRDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVI 3374
T+ I + + RD GVY CTA N VG A ++ V G
Sbjct: 459 YTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------------- 504
Query: 3375 SPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
P IR R+ A G +I C V+G P + W +D L
Sbjct: 505 ---------PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL 543
Score = 66.9 bits (156), Expect = 1e-09
Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V L+C++ S + T+ WYRN VL D + R + TL + +A S S Y
Sbjct: 329 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---TLLITSAQKSHSGAYQ 385
Query: 2666 CTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
C + T+ + + + +P I +F+ + + + L C +G P P
Sbjct: 386 CFATRK---AQTAQDFAIIALEDGTPRIVSSFSEKVVN----PGEQFSLMCAAKGAPPPT 438
Query: 2725 ITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
+TW DD+ I DG R + ++DG + + + P D G Y C A N V + +
Sbjct: 439 VTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA 498
Query: 2781 FVNFTGRESQVSPNVVTA 2798
+N G S + +TA
Sbjct: 499 RINVRGPPSIRAMRNITA 516
Score = 64.9 bits (151), Expect = 5e-09
Identities = 78/299 (26%), Positives = 117/299 (39%), Gaps = 42/299 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCC 3108
P V + P +LK G T L+C++ G P + W +N V +EA + N
Sbjct: 314 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---T 370
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I G Y C AT KA T A++ +E D P
Sbjct: 371 LLITSAQKSHSGAYQCFATR---KAQTAQDFAIIA------------------LE-DGTP 408
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD--KRRNKYQDEQFHT-- 3224
+ ++ V L C G+PPP V+W D E +V D R N+Y T
Sbjct: 409 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 468
Query: 3225 -LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGD 3283
+ + + DGGVY TARN G+ + V +G P + + + D
Sbjct: 469 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV-RG------PPSIRAMRNITAVAGRD 521
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
L I+ V YP + WY+D + L + R ++ +G ++L D G Y C+
Sbjct: 522 TL-INCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCS 576
Score = 61.7 bits (143), Expect = 5e-08
Identities = 88/381 (23%), Positives = 154/381 (40%), Gaps = 61/381 (16%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP---TVTWYRNGVLLDNKLKYRKKLVDGL 2648
R+P ++ + D+ ++ G+ C + SS V+W ++ V + + ++ GL
Sbjct: 124 REP-YTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPENRFFITYHGGL 182
Query: 2649 ITLEVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
+V + Y C +++ +G S ++ + A IP +I D FH
Sbjct: 183 YISDVQKE--DALSTYRCITKHKYSGETRQSNGARLSVTDPAESIP-----TILDGFHSQ 235
Query: 2708 E----NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
E + + L C G P+P I W KD + +P+D R+ + L I + EDSG
Sbjct: 236 EVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRW-----TKRITGLTISDLRTEDSG 290
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TY C+ N+ + + TG + P VT ++ +
Sbjct: 291 TYICEVTNTFGSAEA------TGILMVIDPLHVTLTPKKL-------------------K 325
Query: 2824 VARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTETES 2880
G T+ L + G P + W R TE+ +GL TL ++ ++ S
Sbjct: 326 TGIGSTVILSCALTGSPEFTIRWYRN----TELVLPDEAISIRGLSNETLLITSAQKSHS 381
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
G Y C A + + AI ++ DG P ++ EK +++ GE ++ +G
Sbjct: 382 GAYQCFA-TRKAQTAQDFAIIALE----DGTPRIVSSFSEK--VVNPGEQFSLMCAAKGA 434
Query: 2941 PKPKAVPERIPGEPCVVDGGN 2961
P P V + EP V DG +
Sbjct: 435 P-PPTVTWALDDEPIVRDGSH 454
Score = 59.3 bits (137), Expect = 2e-07
Identities = 81/363 (22%), Positives = 139/363 (38%), Gaps = 49/363 (13%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLE 2652
+ S+F +++ G + L C+ + PTVTW + ++ D + + + T+
Sbjct: 410 IVSSF-SEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 468
Query: 2653 VLNAV-PS--DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+N P D Y CT N G+ A + V PP+ R++R+ +A
Sbjct: 469 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------PPSI-RAMRNITAVAGR 520
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ ++ CR+ G P I W+KD +P + R F +G +L D D G Y C
Sbjct: 521 DTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCSV 577
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
+ +S +V A K Q E G +L V G
Sbjct: 578 --------------LIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGD 623
Query: 2830 IGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
+ P R+ W ++G+ + + ++ + +L +S V+ +G YTC A +
Sbjct: 624 M---------PIRITWRKDGQVIIS-GSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 673
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A V + V P P +V +D + +N S G P PK + +
Sbjct: 674 AAATVSRERQLIVRVP------PRFVVQPNNQDGIYGKAGVLNCS--VDGYPPPKVMWKH 725
Query: 2950 IPG 2952
G
Sbjct: 726 AKG 728
Score = 49.6 bits (113), Expect = 2e-04
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 19/205 (9%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
AR+++ +R + R P + + TAV G + C VI ++ WY++ +LL
Sbjct: 487 ARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLP 546
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV-ENENGAISTSAN--LKVYPSFEASP 2691
+ +++V TL++ + D EY C+V +IS S + +KV P +
Sbjct: 547 DN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFE 603
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVC 2750
PP + L + C + +P +ITW KD + I S G + +
Sbjct: 604 FPPASIGQL----------LYIPCVVSSGDMPIRITWRKDGQVIIS-GSGVTIESKEFMS 652
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWT 2775
L I + + + +G YTC A N+ T
Sbjct: 653 SLQISSVSLKHNGNYTCIASNAAAT 677
Score = 48.4 bits (110), Expect = 5e-04
Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 14/175 (8%)
Query: 2608 GSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G + + C V S P +TW ++G ++ + + + + +L++ + + Y+C
Sbjct: 610 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTC 669
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
N +S L V +PP F + + VL C + G P PK+
Sbjct: 670 IASNAAATVSRERQLIVR-------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVM 722
Query: 2727 WFKDDKQIPSDGRYQAFYLADGV-----CRLAIDNPTPEDSGTYTCKAENSVWTD 2776
W K K + +Y L + L I + ED G Y C+A N V TD
Sbjct: 723 W-KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTD 776
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
+L +G++Y V G G SS+ + + AG P + G + + L
Sbjct: 1254 HLNRGQQYLLWVAAVTSAGRGNSSE---KVTIEPAGKAPAKIISFGGTVTTPWMKDVRLP 1310
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C+ G P P V W K+ + + + L ++ + +D G Y+C ATNT G
Sbjct: 1311 CNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGG 1370
Query: 3132 KASTYARLAV 3141
+ L V
Sbjct: 1371 FDTIIVNLLV 1380
Score = 45.2 bits (102), Expect = 0.004
Identities = 43/160 (26%), Positives = 63/160 (39%), Gaps = 11/160 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCH 3252
G P +++W KDG+ ++ E +L+I+ +L G Y A N + VS
Sbjct: 622 GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRE 681
Query: 3253 CGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
L+V R V P + +Y G ++ V+ YP V W P +
Sbjct: 682 RQLIVRVPPRFVVQPN---NQDGIY----GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734
Query: 3313 RAIMTLDRDGQI----ELALAAVTTRDAGVYTCTASNEVG 3348
+ L QI L + V D G Y C ASN VG
Sbjct: 735 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 774
Score = 39.9 bits (89), Expect = 0.16
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLEIAPTNLDDGGVYEVTAR 3243
VRL C +G P P V W KD E+ + ++ + TL + +D G Y TA
Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366
Query: 3244 NNSG 3247
N G
Sbjct: 1367 NTGG 1370
Score = 38.3 bits (85), Expect = 0.48
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 25/138 (18%)
Query: 3065 GETANLTCSVKGKPVP-GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G+ + C V +P + W K+G + +G +T + F L I +++ G Y+
Sbjct: 610 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSG-VTIESKEFMSSLQISSVSLKHNGNYT 668
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C A+N A A + RER V PP+F ++ ++
Sbjct: 669 CIASN---------------------AAATVSRERQLIVR--VPPRFVVQPNNQDGIYGK 705
Query: 3184 PVRLTCQVIGSPPPKVSW 3201
L C V G PPPKV W
Sbjct: 706 AGVLNCSVDGYPPPKVMW 723
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK---NGHEVEEEAGRMTSQFNGF- 3105
P FV + P + G+ L CSV G P P V+W +G+ + +T +
Sbjct: 690 PRFV-VQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILP 748
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHG 3131
+ L I+ + +D G Y C+A+N G
Sbjct: 749 NSSLLIRHVLEEDIGYYLCQASNGVG 774
Score = 35.1 bits (77), Expect = 4.5
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Query: 2713 LECRIRGQPLPKITWFKD--DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C G P P + W KD D IP +G L + EDSG YTC A
Sbjct: 1309 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT--LLLRAVKAEDSGYYTCTAT 1366
Query: 2771 NSVWTDQI 2778
N+ D I
Sbjct: 1367 NTGGFDTI 1374
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1a protein.
Length = 2053
Score = 89.8 bits (213), Expect = 1e-16
Identities = 104/408 (25%), Positives = 160/408 (39%), Gaps = 66/408 (16%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPG--QLKILAGETANLTCSVKGKP 3078
+R +++Y GE+ Q S+ + + IL G ++ AG T L C+ G P
Sbjct: 196 YRCITKHKYS-GETRQ-SNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYP 253
Query: 3079 VPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYAR 3138
+P + W+K+G + ++ R T + G LTI D+ +D G Y CE TNT G A
Sbjct: 254 IPAIRWLKDGRPLPADS-RWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGI 308
Query: 3139 LAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
L V+ V KLK + +T V L+C + GSP
Sbjct: 309 LMVIDPLHVTLTPKKLK---------------------TGIGST--VILSCALTGSPEFT 345
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
+ WY++ E V+ D+ + + TL I G Y+ A + + ++
Sbjct: 346 IRWYRNTELVLPDEAIS-IRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALE 404
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG---VRLRPSRRAI 3315
G V+ F E + ++ G++ + + P VTW D VR R
Sbjct: 405 DGTPRIVS-SFS---EKV--VNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 458
Query: 3316 MTLDRDGQIE-LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVI 3374
T+ I + + RD GVY CTA N VG A ++ V G
Sbjct: 459 YTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------------- 504
Query: 3375 SPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
P IR R+ A G +I C V+G P + W +D L
Sbjct: 505 ---------PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL 543
Score = 66.1 bits (154), Expect = 2e-09
Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V L+C++ S + T+ WYRN VL D + R + TL + +A S S Y
Sbjct: 329 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---TLLITSAQKSHSGAYQ 385
Query: 2666 CTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
C + T+ + + + +P I +F+ + + + L C +G P P
Sbjct: 386 CFATRK---AQTAQDFAIIALEDGTPRIVSSFSEKVVN----PGEQFSLMCAAKGAPPPT 438
Query: 2725 ITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
+TW DD+ I DG R + ++DG + + + P D G Y C A N V + +
Sbjct: 439 VTWALDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQA 498
Query: 2781 FVNFTGRESQVSPNVVTA 2798
+N G S + +TA
Sbjct: 499 RINVRGPPSIRAMRNITA 516
Score = 64.9 bits (151), Expect = 5e-09
Identities = 78/299 (26%), Positives = 117/299 (39%), Gaps = 42/299 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCC 3108
P V + P +LK G T L+C++ G P + W +N V +EA + N
Sbjct: 314 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---T 370
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I G Y C AT KA T A++ +E D P
Sbjct: 371 LLITSAQKSHSGAYQCFATR---KAQTAQDFAIIA------------------LE-DGTP 408
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD--KRRNKYQDEQFHT-- 3224
+ ++ V L C G+PPP V+W D E +V D R N+Y T
Sbjct: 409 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 468
Query: 3225 -LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGD 3283
+ + + DGGVY TARN G+ + V +G P + + + D
Sbjct: 469 YMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV-RG------PPSIRAMRNITAVAGRD 521
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
L I+ V YP + WY+D + L + R ++ +G ++L D G Y C+
Sbjct: 522 TL-INCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCS 576
Score = 59.3 bits (137), Expect = 2e-07
Identities = 75/306 (24%), Positives = 123/306 (40%), Gaps = 55/306 (17%)
Query: 2664 YSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAE----NELVLECRIR 2718
Y C +++ +G S ++ + A IP +I D FH E + + L C
Sbjct: 196 YRCITKHKYSGETRQSNGARLSVTDPAESIP-----TILDGFHSQEVWAGHTVELPCTAS 250
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
G P+P I W KD + +P+D R+ + L I + EDSGTY C+ N+ + +
Sbjct: 251 GYPIPAIRWLKDGRPLPADSRW-----TKRITGLTISDLRTEDSGTYICEVTNTFGSAEA 305
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
TG + P VT ++ + G T+ L + G
Sbjct: 306 ------TGILMVIDPLHVTLTPKKL-------------------KTGIGSTVILSCALTG 340
Query: 2839 CPT-RVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTETESGLYTCRAWSAHGNVD 2895
P + W R TE+ +GL TL ++ ++ SG Y C A +
Sbjct: 341 SPEFTIRWYRN----TELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFA-TRKAQTA 395
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPC 2955
+ AI ++ DG P ++ EK +++ GE ++ +G P P V + EP
Sbjct: 396 QDFAIIALE----DGTPRIVSSFSEK--VVNPGEQFSLMCAAKGAP-PPTVTWALDDEPI 448
Query: 2956 VVDGGN 2961
V DG +
Sbjct: 449 VRDGSH 454
Score = 56.0 bits (129), Expect = 2e-06
Identities = 80/363 (22%), Positives = 138/363 (38%), Gaps = 49/363 (13%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLE 2652
+ S+F +++ G + L C+ + PTVTW + ++ D + + + T+
Sbjct: 410 IVSSF-SEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 468
Query: 2653 VLNAV-PS--DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+N P D Y CT N G+ A + V PP+ R++R+ +A
Sbjct: 469 YMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------PPSI-RAMRNITAVAGR 520
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ ++ CR+ G P I W+KD +P + R F +G +L D D G Y C
Sbjct: 521 DTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCSV 577
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
+ +S +V A K Q E G +L V G
Sbjct: 578 --------------LIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGD 623
Query: 2830 IGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
+ P R+ W ++G+ + + ++ + +L +S V+ +G TC A +
Sbjct: 624 M---------PIRITWRKDGQVIIS-GSGVTIESKEFMSSLQISSVSLKHNGNDTCIASN 673
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A V + V P P +V +D + +N S G P PK + +
Sbjct: 674 AAATVSRERQLIVRVP------PRFVVQPNNQDGIYGKAGVLNCS--VDGYPPPKVMWKH 725
Query: 2950 IPG 2952
G
Sbjct: 726 AKG 728
Score = 48.0 bits (109), Expect = 6e-04
Identities = 76/340 (22%), Positives = 127/340 (37%), Gaps = 53/340 (15%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G V+L C+ P + W ++G L ++ K++ +T+ L DS Y C
Sbjct: 240 GHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG--LTISDLRT--EDSGTYICE 295
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
V N G+ + L V + P I T ++L C + G P I W
Sbjct: 296 VTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGST-------VILSCALTGSPEFTIRW 348
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
+++ + + D L++ L I + SG Y C F R
Sbjct: 349 YRNTELVLPDEAISIRGLSNET--LLITSAQKSHSGAYQC----------------FATR 390
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWL 2846
++Q TA+ I +LE P + ++ V G L +G P V W
Sbjct: 391 KAQ------TAQDFAII--ALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 442
Query: 2847 REGRSVTE--VYRNARVFVEQGLYTLALSDVTE---TESGLYTCRAWSAHGNVDMNAAIT 2901
+ + +R + + G T++ +VT + G+Y C A + G+ + A I
Sbjct: 443 LDDEPIVRDGSHRTNQYTMSDGT-TISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARIN 501
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEP 2941
V G P++ R ++I G D I+ R G P
Sbjct: 502 V------RGPPSI---RAMRNITAVAGRDTLINCRVIGYP 532
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
+L +G++Y V G G SS+ + + AG P + G + + L
Sbjct: 1254 HLNRGQQYLLWVAAVTSAGRGNSSE---KVTIEPAGKAPAKIISFGGTVTTPWMKDVRLP 1310
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C+ G P P V W K+ + + + L ++ + +D G Y+C ATNT G
Sbjct: 1311 CNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGG 1370
Query: 3132 KASTYARLAV 3141
+ L V
Sbjct: 1371 FDTIIVNLLV 1380
Score = 45.6 bits (103), Expect = 0.003
Identities = 51/205 (24%), Positives = 89/205 (43%), Gaps = 19/205 (9%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
AR+++ +R + R P + + TAV G + C VI ++ WY++ +LL
Sbjct: 487 ARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLP 546
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV-ENENGAISTSAN--LKVYPSFEASP 2691
+ +++V TL++ + D EY C+V +IS S + +KV P +
Sbjct: 547 DN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFE 603
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVC 2750
PP + L + C + +P +ITW KD + I S G + +
Sbjct: 604 FPPASIGQL----------LYIPCVVSSGDMPIRITWRKDGQVIIS-GSGVTIESKEFMS 652
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWT 2775
L I + + + +G TC A N+ T
Sbjct: 653 SLQISSVSLKHNGNDTCIASNAAAT 677
Score = 44.4 bits (100), Expect = 0.007
Identities = 41/175 (23%), Positives = 69/175 (39%), Gaps = 14/175 (8%)
Query: 2608 GSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G + + C V S P +TW ++G ++ + + + + +L++ + + +C
Sbjct: 610 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTC 669
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
N +S L V +PP F + + VL C + G P PK+
Sbjct: 670 IASNAAATVSRERQLIVR-------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVM 722
Query: 2727 WFKDDKQIPSDGRYQAFYLADGV-----CRLAIDNPTPEDSGTYTCKAENSVWTD 2776
W K K + +Y L + L I + ED G Y C+A N V TD
Sbjct: 723 W-KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTD 776
Score = 41.1 bits (92), Expect = 0.068
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 11/160 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCH 3252
G P +++W KDG+ ++ E +L+I+ +L G A N + VS
Sbjct: 622 GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRE 681
Query: 3253 CGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
L+V R V P + +Y G ++ V+ YP V W P +
Sbjct: 682 RQLIVRVPPRFVVQPN---NQDGIY----GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734
Query: 3313 RAIMTLDRDGQI----ELALAAVTTRDAGVYTCTASNEVG 3348
+ L QI L + V D G Y C ASN VG
Sbjct: 735 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 774
Score = 39.9 bits (89), Expect = 0.16
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLEIAPTNLDDGGVYEVTAR 3243
VRL C +G P P V W KD E+ + ++ + TL + +D G Y TA
Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366
Query: 3244 NNSG 3247
N G
Sbjct: 1367 NTGG 1370
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK---NGHEVEEEAGRMTSQFNGF- 3105
P FV + P + G+ L CSV G P P V+W +G+ + +T +
Sbjct: 690 PRFV-VQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILP 748
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHG 3131
+ L I+ + +D G Y C+A+N G
Sbjct: 749 NSSLLIRHVLEEDIGYYLCQASNGVG 774
Score = 35.1 bits (77), Expect = 4.5
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Query: 2713 LECRIRGQPLPKITWFKD--DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C G P P + W KD D IP +G L + EDSG YTC A
Sbjct: 1309 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT--LLLRAVKAEDSGYYTCTAT 1366
Query: 2771 NSVWTDQI 2778
N+ D I
Sbjct: 1367 NTGGFDTI 1374
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 89.8 bits (213), Expect = 1e-16
Identities = 104/408 (25%), Positives = 160/408 (39%), Gaps = 66/408 (16%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPG--QLKILAGETANLTCSVKGKP 3078
+R +++Y GE+ Q S+ + + IL G ++ AG T L C+ G P
Sbjct: 235 YRCITKHKYS-GETRQ-SNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYP 292
Query: 3079 VPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYAR 3138
+P + W+K+G + ++ R T + G LTI D+ +D G Y CE TNT G A
Sbjct: 293 IPAIRWLKDGRPLPADS-RWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGI 347
Query: 3139 LAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPK 3198
L V+ V KLK + +T V L+C + GSP
Sbjct: 348 LMVIDPLHVTLTPKKLK---------------------TGIGST--VILSCALTGSPEFT 384
Query: 3199 VSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
+ WY++ E V+ D+ + + TL I G Y+ A + + ++
Sbjct: 385 IRWYRNTELVLPDEAIS-IRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALE 443
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG---VRLRPSRRAI 3315
G V+ F E + ++ G++ + + P VTW D VR R
Sbjct: 444 DGTPRIVS-SFS---EKV--VNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 497
Query: 3316 MTLDRDGQI-ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVI 3374
T+ I + + RD GVY CTA N VG A ++ V G
Sbjct: 498 YTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------------- 543
Query: 3375 SPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFL 3422
P IR R+ A G +I C V+G P + W +D L
Sbjct: 544 ---------PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL 582
Score = 66.9 bits (156), Expect = 1e-09
Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V L+C++ S + T+ WYRN VL D + R + TL + +A S S Y
Sbjct: 368 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---TLLITSAQKSHSGAYQ 424
Query: 2666 CTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
C + T+ + + + +P I +F+ + + + L C +G P P
Sbjct: 425 CFATRK---AQTAQDFAIIALEDGTPRIVSSFSEKVVN----PGEQFSLMCAAKGAPPPT 477
Query: 2725 ITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
+TW DD+ I DG R + ++DG + + + P D G Y C A N V + +
Sbjct: 478 VTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA 537
Query: 2781 FVNFTGRESQVSPNVVTA 2798
+N G S + +TA
Sbjct: 538 RINVRGPPSIRAMRNITA 555
Score = 64.9 bits (151), Expect = 5e-09
Identities = 78/299 (26%), Positives = 117/299 (39%), Gaps = 42/299 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EEEAGRMTSQFNGFDCC 3108
P V + P +LK G T L+C++ G P + W +N V +EA + N
Sbjct: 353 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---T 409
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I G Y C AT KA T A++ +E D P
Sbjct: 410 LLITSAQKSHSGAYQCFATR---KAQTAQDFAIIA------------------LE-DGTP 447
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD--KRRNKYQDEQFHT-- 3224
+ ++ V L C G+PPP V+W D E +V D R N+Y T
Sbjct: 448 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 507
Query: 3225 -LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGD 3283
+ + + DGGVY TARN G+ + V +G P + + + D
Sbjct: 508 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV-RG------PPSIRAMRNITAVAGRD 560
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
L I+ V YP + WY+D + L + R ++ +G ++L D G Y C+
Sbjct: 561 TL-INCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCS 615
Score = 61.7 bits (143), Expect = 5e-08
Identities = 88/381 (23%), Positives = 154/381 (40%), Gaps = 61/381 (16%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP---TVTWYRNGVLLDNKLKYRKKLVDGL 2648
R+P ++ + D+ ++ G+ C + SS V+W ++ V + + ++ GL
Sbjct: 163 REP-YTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPENRFFITYHGGL 221
Query: 2649 ITLEVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
+V + Y C +++ +G S ++ + A IP +I D FH
Sbjct: 222 YISDVQKE--DALSTYRCITKHKYSGETRQSNGARLSVTDPAESIP-----TILDGFHSQ 274
Query: 2708 E----NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
E + + L C G P+P I W KD + +P+D R+ + L I + EDSG
Sbjct: 275 EVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRW-----TKRITGLTISDLRTEDSG 329
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TY C+ N+ + + TG + P VT ++ +
Sbjct: 330 TYICEVTNTFGSAEA------TGILMVIDPLHVTLTPKKL-------------------K 364
Query: 2824 VARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTETES 2880
G T+ L + G P + W R TE+ +GL TL ++ ++ S
Sbjct: 365 TGIGSTVILSCALTGSPEFTIRWYRN----TELVLPDEAISIRGLSNETLLITSAQKSHS 420
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
G Y C A + + AI ++ DG P ++ EK +++ GE ++ +G
Sbjct: 421 GAYQCFA-TRKAQTAQDFAIIALE----DGTPRIVSSFSEK--VVNPGEQFSLMCAAKGA 473
Query: 2941 PKPKAVPERIPGEPCVVDGGN 2961
P P V + EP V DG +
Sbjct: 474 P-PPTVTWALDDEPIVRDGSH 493
Score = 59.3 bits (137), Expect = 2e-07
Identities = 81/363 (22%), Positives = 139/363 (38%), Gaps = 49/363 (13%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLE 2652
+ S+F +++ G + L C+ + PTVTW + ++ D + + + T+
Sbjct: 449 IVSSF-SEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 507
Query: 2653 VLNAV-PS--DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+N P D Y CT N G+ A + V PP+ R++R+ +A
Sbjct: 508 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------PPSI-RAMRNITAVAGR 559
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ ++ CR+ G P I W+KD +P + R F +G +L D D G Y C
Sbjct: 560 DTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCSV 616
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
+ +S +V A K Q E G +L V G
Sbjct: 617 --------------LIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGD 662
Query: 2830 IGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
+ P R+ W ++G+ + + ++ + +L +S V+ +G YTC A +
Sbjct: 663 M---------PIRITWRKDGQVIIS-GSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 712
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A V + V P P +V +D + +N S G P PK + +
Sbjct: 713 AAATVSRERQLIVRVP------PRFVVQPNNQDGIYGKAGVLNCS--VDGYPPPKVMWKH 764
Query: 2950 IPG 2952
G
Sbjct: 765 AKG 767
Score = 49.6 bits (113), Expect = 2e-04
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 19/205 (9%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
AR+++ +R + R P + + TAV G + C VI ++ WY++ +LL
Sbjct: 526 ARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLP 585
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV-ENENGAISTSAN--LKVYPSFEASP 2691
+ +++V TL++ + D EY C+V +IS S + +KV P +
Sbjct: 586 DN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFE 642
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVC 2750
PP + L + C + +P +ITW KD + I S G + +
Sbjct: 643 FPPASIGQL----------LYIPCVVSSGDMPIRITWRKDGQVIIS-GSGVTIESKEFMS 691
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWT 2775
L I + + + +G YTC A N+ T
Sbjct: 692 SLQISSVSLKHNGNYTCIASNAAAT 716
Score = 48.4 bits (110), Expect = 5e-04
Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 14/175 (8%)
Query: 2608 GSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G + + C V S P +TW ++G ++ + + + + +L++ + + Y+C
Sbjct: 649 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTC 708
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
N +S L V +PP F + + VL C + G P PK+
Sbjct: 709 IASNAAATVSRERQLIVR-------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVM 761
Query: 2727 WFKDDKQIPSDGRYQAFYLADGV-----CRLAIDNPTPEDSGTYTCKAENSVWTD 2776
W K K + +Y L + L I + ED G Y C+A N V TD
Sbjct: 762 W-KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTD 815
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
+L +G++Y V G G SS+ + + AG P + G + + L
Sbjct: 1293 HLNRGQQYLLWVAAVTSAGRGNSSE---KVTIEPAGKAPAKIISFGGTVTTPWMKDVRLP 1349
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C+ G P P V W K+ + + + L ++ + +D G Y+C ATNT G
Sbjct: 1350 CNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGG 1409
Query: 3132 KASTYARLAV 3141
+ L V
Sbjct: 1410 FDTIIVNLLV 1419
Score = 45.2 bits (102), Expect = 0.004
Identities = 43/160 (26%), Positives = 63/160 (39%), Gaps = 11/160 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCH 3252
G P +++W KDG+ ++ E +L+I+ +L G Y A N + VS
Sbjct: 661 GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRE 720
Query: 3253 CGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
L+V R V P + +Y G ++ V+ YP V W P +
Sbjct: 721 RQLIVRVPPRFVVQPN---NQDGIY----GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 773
Query: 3313 RAIMTLDRDGQI----ELALAAVTTRDAGVYTCTASNEVG 3348
+ L QI L + V D G Y C ASN VG
Sbjct: 774 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 813
Score = 39.9 bits (89), Expect = 0.16
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLEIAPTNLDDGGVYEVTAR 3243
VRL C +G P P V W KD E+ + ++ + TL + +D G Y TA
Sbjct: 1346 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1405
Query: 3244 NNSG 3247
N G
Sbjct: 1406 NTGG 1409
Score = 38.3 bits (85), Expect = 0.48
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 25/138 (18%)
Query: 3065 GETANLTCSVKGKPVP-GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G+ + C V +P + W K+G + +G +T + F L I +++ G Y+
Sbjct: 649 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSG-VTIESKEFMSSLQISSVSLKHNGNYT 707
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C A+N A A + RER V PP+F ++ ++
Sbjct: 708 CIASN---------------------AAATVSRERQLIVR--VPPRFVVQPNNQDGIYGK 744
Query: 3184 PVRLTCQVIGSPPPKVSW 3201
L C V G PPPKV W
Sbjct: 745 AGVLNCSVDGYPPPKVMW 762
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK---NGHEVEEEAGRMTSQFNGF- 3105
P FV + P + G+ L CSV G P P V+W +G+ + +T +
Sbjct: 729 PRFV-VQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILP 787
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHG 3131
+ L I+ + +D G Y C+A+N G
Sbjct: 788 NSSLLIRHVLEEDIGYYLCQASNGVG 813
Score = 35.1 bits (77), Expect = 4.5
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Query: 2713 LECRIRGQPLPKITWFKD--DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C G P P + W KD D IP +G L + EDSG YTC A
Sbjct: 1348 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT--LLLRAVKAEDSGYYTCTAT 1405
Query: 2771 NSVWTDQI 2778
N+ D I
Sbjct: 1406 NTGGFDTI 1413
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 89.4 bits (212), Expect = 2e-16
Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 48/305 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + L G+ L C G PVP + W K V+ G ++ Q+ + L I ++
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRK----VD---GSLSPQWTTAEPTLQIPSVSF 298
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+DEG Y CEA N+ G+ + R+ V P++ + D
Sbjct: 299 EDEGTYECEAENSKGRDTVQGRIIVQAQ-----------------------PEWLKVISD 335
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R C G P P V W ++GE + R + L + +L+D G
Sbjct: 336 TEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSG 391
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL---HEGDELRISAVVEA 3293
+Y+ A N G + L V +AP+F L P+ +L G E+ I A
Sbjct: 392 MYQCVAENKHGTIYASAELAVQA-----LAPDF--RLNPVRRLIPAARGGEILIPCQPRA 444
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
P V W + L S R +T+ DG L + ++ D G YTC A N +G+A+++
Sbjct: 445 APKAVVLWSKGTEILVNSSR--VTVTPDGT--LIIRNISRSDEGKYTCFAENFMGKANST 500
Query: 3354 GKVEV 3358
G + V
Sbjct: 501 GILSV 505
Score = 65.7 bits (153), Expect = 3e-09
Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 18/182 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P + ++D A GS ++ C+ PTV W RNG L + + R +++ G +
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS--QNRVEVLAGDLRFS 383
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
L+ DS Y C EN++G I SA L V P F +P+ +
Sbjct: 384 KLSL--EDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAA-------RGG 434
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
E+++ C+ R P + W K + + + R DG L I N + D G YTC A
Sbjct: 435 EILIPCQPRAAPKAVVLWSKGTEILVNSSRVTV--TPDGT--LIIRNISRSDEGKYTCFA 490
Query: 2770 EN 2771
EN
Sbjct: 491 EN 492
Score = 52.8 bits (121), Expect = 2e-05
Identities = 62/250 (24%), Positives = 99/250 (39%), Gaps = 29/250 (11%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I N D G YSC AT+ H ST + + + D +L + ++ +P
Sbjct: 192 LYIARTNASDLGNYSCLATS-HMDFSTKSVFSKFAQLNLAAEDTRLF---APSIKARFPA 247
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+ T L ++V L C G+P P++ W K D + TL+I
Sbjct: 248 E-TYALVGQQVT------LECFAFGNPVPRIKWRK------VDGSLSPQWTTAEPTLQIP 294
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
+ +D G YE A N+ G + ++V PE+ + + G LR
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQ------AQPEWLKVISDT-EADIGSNLRWG 347
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P V W R+G L S+ + L D L + ++ D+G+Y C A N+ G
Sbjct: 348 CAAAGKPRPTVRWLRNGEPL-ASQNRVEVLAGD----LRFSKLSLEDSGMYQCVAENKHG 402
Query: 3349 RASTSGKVEV 3358
S ++ V
Sbjct: 403 TIYASAELAV 412
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/319 (24%), Positives = 117/319 (36%), Gaps = 45/319 (14%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+PE++ ++ + G C+ GKP P V W++NG E A + + D
Sbjct: 326 QPEWLKVI-SDTEADIGSNLRWGCAAAGKPRPTVRWLRNG---EPLASQNRVEVLAGD-- 379
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L ++++D G Y C A N HG A LAV +A A P
Sbjct: 380 LRFSKLSLEDSGMYQCVAENKHGTIYASAELAV-------QALA---------------P 417
Query: 3169 QFTMRLRDRRVQATY--PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
F + R + A + + CQ +P V W K E +V R D TL
Sbjct: 418 DFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPD---GTLI 474
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I + D G Y A N G + L V + +AP ++ GD L
Sbjct: 475 IRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSA-------DINLGDNLT 527
Query: 3287 ISAVVEAYPSVGV--TWYRDGVRL---RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+ P++ + TW D + +P T ++ +L + R G YTC
Sbjct: 528 LQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTC 587
Query: 3342 TASNEVGRASTSGKVEVIG 3360
A V AS V V G
Sbjct: 588 MAQTVVDSASKEATVLVRG 606
Score = 48.8 bits (111), Expect = 3e-04
Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 15/174 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G + + C ++ V W + +L N + DG TL + N SD +Y
Sbjct: 430 AARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDG--TLIIRNISRSDEGKY 486
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
+C EN G +++ L V +A+ I T S D +L +N L L+C P
Sbjct: 487 TCFAENFMGKANSTGILSVR---DATKI--TLAPSSAD-INLGDN-LTLQCHASHDPTMD 539
Query: 2725 I--TWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ TW DD I D G Y+ + + + L I N G YTC A+ V
Sbjct: 540 LTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVV 593
Score = 48.0 bits (109), Expect = 6e-04
Identities = 79/341 (23%), Positives = 135/341 (39%), Gaps = 47/341 (13%)
Query: 2610 RVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV 2668
+V L C +S T W NG + + R +LV G L ++N + D+ Y C
Sbjct: 56 QVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGG--NLVIMNPTKAQDAGVYQCLA 113
Query: 2669 ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELVLECRIRGQ-PLPKIT 2726
N G + + + + + F++ RD E ++L C P
Sbjct: 114 SNPVGTVVSREAILRFGFLQ------EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYR 167
Query: 2727 WFKDD--KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W ++ IP+DGR+ +++ L I D G Y+C A + + + F F
Sbjct: 168 WLLNEFPNFIPTDGRH---FVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKF 224
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RV 2843
+Q++ + AE TR+ S+++R P L QV L+ G P R+
Sbjct: 225 ----AQLN---LAAEDTRLFAPSIKARFPAETYALVGQQVT------LECFAFGNPVPRI 271
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV- 2902
+W + S++ + A TL + V+ + G Y C A ++ G + I V
Sbjct: 272 KWRKVDGSLSPQWTTAEP-------TLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 2903 VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
QP L ++ E DI G ++ G+P+P
Sbjct: 325 AQPEWLK-----VISDTEADI----GSNLRWGCAAAGKPRP 356
Score = 45.6 bits (103), Expect = 0.003
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 20/235 (8%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
V L C+ SPP W +G E+ + +++Q + + + PT D GVY+ A N
Sbjct: 57 VLLACRARASPPATYRWKMNGTEMKLEPG-SRHQLVGGNLVIMNPTKAQDAGVYQCLASN 115
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA-YPSVGVTW-Y 3302
G V + +R EF K HEG + + A YP + W
Sbjct: 116 PVGTVVSREAI-----LRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLL 170
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+ P+ G L +A D G Y+C A++ + ++ S + +
Sbjct: 171 NEFPNFIPTDGRHFVSQTTG--NLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLN 228
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+E + +P + R P + A G V +EC G+P P + W
Sbjct: 229 LAAE---DTRLFAPSIK-------ARFPAETYALVGQQVTLECFAFGNPVPRIKW 273
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycoprotein
protein.
Length = 1040
Score = 89.4 bits (212), Expect = 2e-16
Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 48/305 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + L G+ L C G PVP + W K V+ G ++ Q+ + L I ++
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRK----VD---GSLSPQWTTAEPTLQIPSVSF 298
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+DEG Y CEA N+ G+ + R+ V P++ + D
Sbjct: 299 EDEGTYECEAENSKGRDTVQGRIIVQAQ-----------------------PEWLKVISD 335
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R C G P P V W ++GE + R + L + +L+D G
Sbjct: 336 TEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSG 391
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL---HEGDELRISAVVEA 3293
+Y+ A N G + L V +AP+F L P+ +L G E+ I A
Sbjct: 392 MYQCVAENKHGTIYASAELAVQA-----LAPDF--RLNPVRRLIPAARGGEILIPCQPRA 444
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
P V W + L S R +T+ DG L + ++ D G YTC A N +G+A+++
Sbjct: 445 APKAVVLWSKGTEILVNSSR--VTVTPDGT--LIIRNISRSDEGKYTCFAENFMGKANST 500
Query: 3354 GKVEV 3358
G + V
Sbjct: 501 GILSV 505
Score = 65.7 bits (153), Expect = 3e-09
Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 18/182 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P + ++D A GS ++ C+ PTV W RNG L + + R +++ G +
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS--QNRVEVLAGDLRFS 383
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
L+ DS Y C EN++G I SA L V P F +P+ +
Sbjct: 384 KLSL--EDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAA-------RGG 434
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
E+++ C+ R P + W K + + + R DG L I N + D G YTC A
Sbjct: 435 EILIPCQPRAAPKAVVLWSKGTEILVNSSRVTV--TPDGT--LIIRNISRSDEGKYTCFA 490
Query: 2770 EN 2771
EN
Sbjct: 491 EN 492
Score = 52.8 bits (121), Expect = 2e-05
Identities = 62/250 (24%), Positives = 99/250 (39%), Gaps = 29/250 (11%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I N D G YSC AT+ H ST + + + D +L + ++ +P
Sbjct: 192 LYIARTNASDLGNYSCLATS-HMDFSTKSVFSKFAQLNLAAEDTRLF---APSIKARFPA 247
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+ T L ++V L C G+P P++ W K D + TL+I
Sbjct: 248 E-TYALVGQQVT------LECFAFGNPVPRIKWRK------VDGSLSPQWTTAEPTLQIP 294
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
+ +D G YE A N+ G + ++V PE+ + + G LR
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQ------AQPEWLKVISDT-EADIGSNLRWG 347
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P V W R+G L S+ + L D L + ++ D+G+Y C A N+ G
Sbjct: 348 CAAAGKPRPTVRWLRNGEPL-ASQNRVEVLAGD----LRFSKLSLEDSGMYQCVAENKHG 402
Query: 3349 RASTSGKVEV 3358
S ++ V
Sbjct: 403 TIYASAELAV 412
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/319 (24%), Positives = 117/319 (36%), Gaps = 45/319 (14%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+PE++ ++ + G C+ GKP P V W++NG E A + + D
Sbjct: 326 QPEWLKVI-SDTEADIGSNLRWGCAAAGKPRPTVRWLRNG---EPLASQNRVEVLAGD-- 379
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L ++++D G Y C A N HG A LAV +A A P
Sbjct: 380 LRFSKLSLEDSGMYQCVAENKHGTIYASAELAV-------QALA---------------P 417
Query: 3169 QFTMRLRDRRVQATY--PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
F + R + A + + CQ +P V W K E +V R D TL
Sbjct: 418 DFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPD---GTLI 474
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I + D G Y A N G + L V + +AP ++ GD L
Sbjct: 475 IRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSA-------DINLGDNLT 527
Query: 3287 ISAVVEAYPSVGV--TWYRDGVRL---RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+ P++ + TW D + +P T ++ +L + R G YTC
Sbjct: 528 LQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTC 587
Query: 3342 TASNEVGRASTSGKVEVIG 3360
A V AS V V G
Sbjct: 588 MAQTVVDSASKEATVLVRG 606
Score = 48.8 bits (111), Expect = 3e-04
Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 15/174 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G + + C ++ V W + +L N + DG TL + N SD +Y
Sbjct: 430 AARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDG--TLIIRNISRSDEGKY 486
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
+C EN G +++ L V +A+ I T S D +L +N L L+C P
Sbjct: 487 TCFAENFMGKANSTGILSVR---DATKI--TLAPSSAD-INLGDN-LTLQCHASHDPTMD 539
Query: 2725 I--TWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ TW DD I D G Y+ + + + L I N G YTC A+ V
Sbjct: 540 LTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVV 593
Score = 48.0 bits (109), Expect = 6e-04
Identities = 79/341 (23%), Positives = 135/341 (39%), Gaps = 47/341 (13%)
Query: 2610 RVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV 2668
+V L C +S T W NG + + R +LV G L ++N + D+ Y C
Sbjct: 56 QVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGG--NLVIMNPTKAQDAGVYQCLA 113
Query: 2669 ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELVLECRIRGQ-PLPKIT 2726
N G + + + + + F++ RD E ++L C P
Sbjct: 114 SNPVGTVVSREAILRFGFLQ------EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYR 167
Query: 2727 WFKDD--KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W ++ IP+DGR+ +++ L I D G Y+C A + + + F F
Sbjct: 168 WLLNEFPNFIPTDGRH---FVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKF 224
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RV 2843
+Q++ + AE TR+ S+++R P L QV L+ G P R+
Sbjct: 225 ----AQLN---LAAEDTRLFAPSIKARFPAETYALVGQQVT------LECFAFGNPVPRI 271
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV- 2902
+W + S++ + A TL + V+ + G Y C A ++ G + I V
Sbjct: 272 KWRKVDGSLSPQWTTAEP-------TLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 2903 VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
QP L ++ E DI G ++ G+P+P
Sbjct: 325 AQPEWLK-----VISDTEADI----GSNLRWGCAAAGKPRP 356
Score = 45.6 bits (103), Expect = 0.003
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 20/235 (8%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
V L C+ SPP W +G E+ + +++Q + + + PT D GVY+ A N
Sbjct: 57 VLLACRARASPPATYRWKMNGTEMKLEPG-SRHQLVGGNLVIMNPTKAQDAGVYQCLASN 115
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA-YPSVGVTW-Y 3302
G V + +R EF K HEG + + A YP + W
Sbjct: 116 PVGTVVSREAI-----LRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLL 170
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+ P+ G L +A D G Y+C A++ + ++ S + +
Sbjct: 171 NEFPNFIPTDGRHFVSQTTG--NLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLN 228
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+E + +P + R P + A G V +EC G+P P + W
Sbjct: 229 LAAE---DTRLFAPSIK-------ARFPAETYALVGQQVTLECFAFGNPVPRIKW 273
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 89.4 bits (212), Expect = 2e-16
Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 48/305 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + L G+ L C G PVP + W K V+ G ++ Q+ + L I ++
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRK----VD---GSLSPQWTTAEPTLQIPSVSF 298
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+DEG Y CEA N+ G+ + R+ V P++ + D
Sbjct: 299 EDEGTYECEAENSKGRDTVQGRIIVQAQ-----------------------PEWLKVISD 335
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R C G P P V W ++GE + R + L + +L+D G
Sbjct: 336 TEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSG 391
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL---HEGDELRISAVVEA 3293
+Y+ A N G + L V +AP+F L P+ +L G E+ I A
Sbjct: 392 MYQCVAENKHGTIYASAELAVQA-----LAPDF--RLNPVRRLIPAARGGEILIPCQPRA 444
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
P V W + L S R +T+ DG L + ++ D G YTC A N +G+A+++
Sbjct: 445 APKAVVLWSKGTEILVNSSR--VTVTPDGT--LIIRNISRSDEGKYTCFAENFMGKANST 500
Query: 3354 GKVEV 3358
G + V
Sbjct: 501 GILSV 505
Score = 65.7 bits (153), Expect = 3e-09
Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 18/182 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P + ++D A GS ++ C+ PTV W RNG L + + R +++ G +
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS--QNRVEVLAGDLRFS 383
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
L+ DS Y C EN++G I SA L V P F +P+ +
Sbjct: 384 KLSL--EDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAA-------RGG 434
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
E+++ C+ R P + W K + + + R DG L I N + D G YTC A
Sbjct: 435 EILIPCQPRAAPKAVVLWSKGTEILVNSSRVTV--TPDGT--LIIRNISRSDEGKYTCFA 490
Query: 2770 EN 2771
EN
Sbjct: 491 EN 492
Score = 52.8 bits (121), Expect = 2e-05
Identities = 62/250 (24%), Positives = 99/250 (39%), Gaps = 29/250 (11%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I N D G YSC AT+ H ST + + + D +L + ++ +P
Sbjct: 192 LYIARTNASDLGNYSCLATS-HMDFSTKSVFSKFAQLNLAAEDTRLF---APSIKARFPA 247
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+ T L ++V L C G+P P++ W K D + TL+I
Sbjct: 248 E-TYALVGQQVT------LECFAFGNPVPRIKWRK------VDGSLSPQWTTAEPTLQIP 294
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
+ +D G YE A N+ G + ++V PE+ + + G LR
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQ------AQPEWLKVISDT-EADIGSNLRWG 347
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P V W R+G L S+ + L D L + ++ D+G+Y C A N+ G
Sbjct: 348 CAAAGKPRPTVRWLRNGEPL-ASQNRVEVLAGD----LRFSKLSLEDSGMYQCVAENKHG 402
Query: 3349 RASTSGKVEV 3358
S ++ V
Sbjct: 403 TIYASAELAV 412
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/319 (24%), Positives = 117/319 (36%), Gaps = 45/319 (14%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+PE++ ++ + G C+ GKP P V W++NG E A + + D
Sbjct: 326 QPEWLKVI-SDTEADIGSNLRWGCAAAGKPRPTVRWLRNG---EPLASQNRVEVLAGD-- 379
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L ++++D G Y C A N HG A LAV +A A P
Sbjct: 380 LRFSKLSLEDSGMYQCVAENKHGTIYASAELAV-------QALA---------------P 417
Query: 3169 QFTMRLRDRRVQATY--PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
F + R + A + + CQ +P V W K E +V R D TL
Sbjct: 418 DFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPD---GTLI 474
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I + D G Y A N G + L V + +AP ++ GD L
Sbjct: 475 IRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSA-------DINLGDNLT 527
Query: 3287 ISAVVEAYPSVGV--TWYRDGVRL---RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+ P++ + TW D + +P T ++ +L + R G YTC
Sbjct: 528 LQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTC 587
Query: 3342 TASNEVGRASTSGKVEVIG 3360
A V AS V V G
Sbjct: 588 MAQTVVDSASKEATVLVRG 606
Score = 48.8 bits (111), Expect = 3e-04
Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 15/174 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G + + C ++ V W + +L N + DG TL + N SD +Y
Sbjct: 430 AARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDG--TLIIRNISRSDEGKY 486
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
+C EN G +++ L V +A+ I T S D +L +N L L+C P
Sbjct: 487 TCFAENFMGKANSTGILSVR---DATKI--TLAPSSAD-INLGDN-LTLQCHASHDPTMD 539
Query: 2725 I--TWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ TW DD I D G Y+ + + + L I N G YTC A+ V
Sbjct: 540 LTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVV 593
Score = 48.0 bits (109), Expect = 6e-04
Identities = 79/341 (23%), Positives = 135/341 (39%), Gaps = 47/341 (13%)
Query: 2610 RVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV 2668
+V L C +S T W NG + + R +LV G L ++N + D+ Y C
Sbjct: 56 QVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGG--NLVIMNPTKAQDAGVYQCLA 113
Query: 2669 ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELVLECRIRGQ-PLPKIT 2726
N G + + + + + F++ RD E ++L C P
Sbjct: 114 SNPVGTVVSREAILRFGFLQ------EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYR 167
Query: 2727 WFKDD--KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W ++ IP+DGR+ +++ L I D G Y+C A + + + F F
Sbjct: 168 WLLNEFPNFIPTDGRH---FVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKF 224
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RV 2843
+Q++ + AE TR+ S+++R P L QV L+ G P R+
Sbjct: 225 ----AQLN---LAAEDTRLFAPSIKARFPAETYALVGQQVT------LECFAFGNPVPRI 271
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV- 2902
+W + S++ + A TL + V+ + G Y C A ++ G + I V
Sbjct: 272 KWRKVDGSLSPQWTTAEP-------TLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 2903 VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
QP L ++ E DI G ++ G+P+P
Sbjct: 325 AQPEWLK-----VISDTEADI----GSNLRWGCAAAGKPRP 356
Score = 45.6 bits (103), Expect = 0.003
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 20/235 (8%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
V L C+ SPP W +G E+ + +++Q + + + PT D GVY+ A N
Sbjct: 57 VLLACRARASPPATYRWKMNGTEMKLEPG-SRHQLVGGNLVIMNPTKAQDAGVYQCLASN 115
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA-YPSVGVTW-Y 3302
G V + +R EF K HEG + + A YP + W
Sbjct: 116 PVGTVVSREAI-----LRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLL 170
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+ P+ G L +A D G Y+C A++ + ++ S + +
Sbjct: 171 NEFPNFIPTDGRHFVSQTTG--NLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLN 228
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+E + +P + R P + A G V +EC G+P P + W
Sbjct: 229 LAAE---DTRLFAPSIK-------ARFPAETYALVGQQVTLECFAFGNPVPRIKW 273
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 89.4 bits (212), Expect = 2e-16
Identities = 85/317 (26%), Positives = 129/317 (40%), Gaps = 35/317 (11%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G++ L C +G P P + W K+G ++E+E F+ LTIK ++ +DE Y C
Sbjct: 228 GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYIC 287
Query: 3125 EATNTHGKASTYARLAV--------VTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
A N G+ L V V ++T E + ++ + E GD P T R
Sbjct: 288 IAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV--TLTCEASGDPIPSITWRTST 345
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R + S K SW + ++ D + +L + D G
Sbjct: 346 RNI--------------SSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAG 391
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y TA N G S L V AP+ G +Y EG+++ I+ V AYPS
Sbjct: 392 EYICTASNTIGQDSQSMYLEVQ------YAPKL-QGPVAVY-TWEGNQVNITCEVFAYPS 443
Query: 3297 VGVTWYRDGVRLRPSRRA-IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
++W+RDG L S + I + L + + D G Y CTA N +G+ S +
Sbjct: 444 ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESL--E 501
Query: 3356 VEVIGTDQTSEPRIPPV 3372
++ D S P I V
Sbjct: 502 FILVQADTPSSPSIDQV 518
Score = 62.9 bits (146), Expect = 2e-08
Identities = 74/332 (22%), Positives = 132/332 (39%), Gaps = 53/332 (15%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVP 2658
+ + TA G V L C +PT++W ++G ++ + K + D L +
Sbjct: 220 IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDK 279
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
+D AEY C EN+ G + +LKV+ P T T E ++ L C
Sbjct: 280 NDEAEYICIAENKAGEQDATIHLKVFAK-------PKITYVENQTAMELEEQVTLTCEAS 332
Query: 2719 GQPLPKITWFKDDKQIPSD-----GRYQAFYLADG---------VCRLAIDNPTPEDSGT 2764
G P+P ITW + I S+ R + DG V L + + D+G
Sbjct: 333 GDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGE 392
Query: 2765 YTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Y C A N++ D + ++ E Q +P + + +A + E
Sbjct: 393 YICTASNTIGQDSQSMYL-----EVQYAPKL----QGPVAVYTWE--------------- 428
Query: 2825 ARGGTIGLQVEIRGCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGL 2882
G + + E+ P+ + W R+G+ + + Y N +++ L ++ +E + G
Sbjct: 429 --GNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN 486
Query: 2883 YTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
Y C A + G + +VQ +D P++
Sbjct: 487 YNCTAVNRIGQESLE--FILVQ-ADTPSSPSI 515
Score = 60.9 bits (141), Expect = 8e-08
Identities = 75/329 (22%), Positives = 119/329 (36%), Gaps = 26/329 (7%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLI 2649
+K +F T + EG + C V+SS PT+ W G V+L +++ +V
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRF---IVLSNN 172
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHL 2706
L++ +D Y C G I + +PPT + T +L
Sbjct: 173 YLQIRGIKKTDEGTYRC-----EGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANL 227
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
++ + L C G P P ++W KD +QI + + + +D +L I D Y
Sbjct: 228 GQS-VTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 2767 CKAENSVWTDQIT-HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVA 2825
C AEN T H F + N E + E+ ++
Sbjct: 287 CIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSI-----TW 341
Query: 2826 RGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTC 2885
R T + E + TR E V +ARV +L L + T++G Y C
Sbjct: 342 RTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARV------SSLTLKSIQYTDAGEYIC 395
Query: 2886 RAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
A + G + + V L G AV
Sbjct: 396 TASNTIGQDSQSMYLEVQYAPKLQGPVAV 424
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/371 (22%), Positives = 135/371 (36%), Gaps = 57/371 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVP-GVVWMK-NGHEVEEEAGRMTSQFNG-FDCCL 3109
VDI+P Q +I GE+ C V G + W NG ++ R++ +N L
Sbjct: 22 VDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTL 81
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
TI + NIDD G Y C T G S EA +K + + PQ
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSES--------------EATVNVKIFQKLMFKNAPTPQ 127
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D + C V+ S PP + W G +V+ K+ ++ + L+I
Sbjct: 128 EFREGED--------AVIVCDVVSSLPPTIIWKHKGRDVIL-KKDVRFIVLSNNYLQIRG 178
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLYK--LHEGDELR 3286
D G Y R + G + K I+ V P + + + G +
Sbjct: 179 IKKTDEGTYRCEGRILAR------GEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVT 232
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ E +P ++W +DG ++ + D +L + V D Y C A N+
Sbjct: 233 LVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENK 292
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
G + ++V ++P+I ++ + E E V + CE
Sbjct: 293 AGEQDATIHLKVF-----AKPKI---------------TYVENQTAMELEE--QVTLTCE 330
Query: 3407 VVGDPKPDVYW 3417
GDP P + W
Sbjct: 331 ASGDPIPSITW 341
Score = 43.2 bits (97), Expect = 0.017
Identities = 71/338 (21%), Positives = 126/338 (37%), Gaps = 50/338 (14%)
Query: 2615 CSVISSS-DPTVTWYR-NGVLLDNKLKYRKKLV---DGLITLEVLNAVPSDSAEYSCTVE 2669
C V + D ++W+ NG L + R +V D TL + NA D+ Y C V
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPN-QQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVT 99
Query: 2670 NENGAIS-TSANLKVYPS--FEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
E+G+ S + N+K++ F+ +P P F + V+ C + P I
Sbjct: 100 GEDGSESEATVNVKIFQKLMFKNAPTPQEFREG---------EDAVIVCDVVSSLPPTII 150
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W + + + L++ L I D GTY C+ + +NF
Sbjct: 151 WKHKGRDVILKKDVRFIVLSNNY--LQIRGIKKTDEGTYRCEGRILARGE-----INF-- 201
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEW 2845
++ QV +V T ARQ++ + + G +T L + G P + W
Sbjct: 202 KDIQV---IVNVPPTIQARQNIVNATANLGQSVT-----------LVCDAEGFPEPTMSW 247
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
++G + + + + L + V + + Y C A + G D + V
Sbjct: 248 TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVF-- 305
Query: 2906 SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP + E + + E + ++ G+P P
Sbjct: 306 ----AKPKITY--VENQTAMELEEQVTLTCEASGDPIP 337
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 89.4 bits (212), Expect = 2e-16
Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 48/305 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + L G+ L C G PVP + W K V+ G ++ Q+ + L I ++
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRK----VD---GSLSPQWTTAEPTLQIPSVSF 298
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+DEG Y CEA N+ G+ + R+ V P++ + D
Sbjct: 299 EDEGTYECEAENSKGRDTVQGRIIVQAQ-----------------------PEWLKVISD 335
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+R C G P P V W ++GE + R + L + +L+D G
Sbjct: 336 TEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSG 391
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL---HEGDELRISAVVEA 3293
+Y+ A N G + L V +AP+F L P+ +L G E+ I A
Sbjct: 392 MYQCVAENKHGTIYASAELAVQA-----LAPDF--RLNPVRRLIPAARGGEILIPCQPRA 444
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
P V W + L S R +T+ DG L + ++ D G YTC A N +G+A+++
Sbjct: 445 APKAVVLWSKGTEILVNSSR--VTVTPDGT--LIIRNISRSDEGKYTCFAENFMGKANST 500
Query: 3354 GKVEV 3358
G + V
Sbjct: 501 GILSV 505
Score = 65.7 bits (153), Expect = 3e-09
Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 18/182 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P + ++D A GS ++ C+ PTV W RNG L + + R +++ G +
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS--QNRVEVLAGDLRFS 383
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
L+ DS Y C EN++G I SA L V P F +P+ +
Sbjct: 384 KLSL--EDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAA-------RGG 434
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
E+++ C+ R P + W K + + + R DG L I N + D G YTC A
Sbjct: 435 EILIPCQPRAAPKAVVLWSKGTEILVNSSRVTV--TPDGT--LIIRNISRSDEGKYTCFA 490
Query: 2770 EN 2771
EN
Sbjct: 491 EN 492
Score = 52.8 bits (121), Expect = 2e-05
Identities = 62/250 (24%), Positives = 99/250 (39%), Gaps = 29/250 (11%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I N D G YSC AT+ H ST + + + D +L + ++ +P
Sbjct: 192 LYIARTNASDLGNYSCLATS-HMDFSTKSVFSKFAQLNLAAEDTRLF---APSIKARFPA 247
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+ T L ++V L C G+P P++ W K D + TL+I
Sbjct: 248 E-TYALVGQQVT------LECFAFGNPVPRIKWRK------VDGSLSPQWTTAEPTLQIP 294
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
+ +D G YE A N+ G + ++V PE+ + + G LR
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQ------AQPEWLKVISDT-EADIGSNLRWG 347
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P V W R+G L S+ + L D L + ++ D+G+Y C A N+ G
Sbjct: 348 CAAAGKPRPTVRWLRNGEPL-ASQNRVEVLAGD----LRFSKLSLEDSGMYQCVAENKHG 402
Query: 3349 RASTSGKVEV 3358
S ++ V
Sbjct: 403 TIYASAELAV 412
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/319 (24%), Positives = 117/319 (36%), Gaps = 45/319 (14%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+PE++ ++ + G C+ GKP P V W++NG E A + + D
Sbjct: 326 QPEWLKVI-SDTEADIGSNLRWGCAAAGKPRPTVRWLRNG---EPLASQNRVEVLAGD-- 379
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L ++++D G Y C A N HG A LAV +A A P
Sbjct: 380 LRFSKLSLEDSGMYQCVAENKHGTIYASAELAV-------QALA---------------P 417
Query: 3169 QFTMRLRDRRVQATY--PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
F + R + A + + CQ +P V W K E +V R D TL
Sbjct: 418 DFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPD---GTLI 474
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I + D G Y A N G + L V + +AP ++ GD L
Sbjct: 475 IRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSA-------DINLGDNLT 527
Query: 3287 ISAVVEAYPSVGV--TWYRDGVRL---RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+ P++ + TW D + +P T ++ +L + R G YTC
Sbjct: 528 LQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTC 587
Query: 3342 TASNEVGRASTSGKVEVIG 3360
A V AS V V G
Sbjct: 588 MAQTVVDSASKEATVLVRG 606
Score = 48.8 bits (111), Expect = 3e-04
Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 15/174 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A G + + C ++ V W + +L N + DG TL + N SD +Y
Sbjct: 430 AARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDG--TLIIRNISRSDEGKY 486
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
+C EN G +++ L V +A+ I T S D +L +N L L+C P
Sbjct: 487 TCFAENFMGKANSTGILSVR---DATKI--TLAPSSAD-INLGDN-LTLQCHASHDPTMD 539
Query: 2725 I--TWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+ TW DD I D G Y+ + + + L I N G YTC A+ V
Sbjct: 540 LTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVV 593
Score = 48.0 bits (109), Expect = 6e-04
Identities = 79/341 (23%), Positives = 135/341 (39%), Gaps = 47/341 (13%)
Query: 2610 RVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV 2668
+V L C +S T W NG + + R +LV G L ++N + D+ Y C
Sbjct: 56 QVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGG--NLVIMNPTKAQDAGVYQCLA 113
Query: 2669 ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELVLECRIRGQ-PLPKIT 2726
N G + + + + + F++ RD E ++L C P
Sbjct: 114 SNPVGTVVSREAILRFGFLQ------EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYR 167
Query: 2727 WFKDD--KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W ++ IP+DGR+ +++ L I D G Y+C A + + + F F
Sbjct: 168 WLLNEFPNFIPTDGRH---FVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKF 224
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RV 2843
+Q++ + AE TR+ S+++R P L QV L+ G P R+
Sbjct: 225 ----AQLN---LAAEDTRLFAPSIKARFPAETYALVGQQVT------LECFAFGNPVPRI 271
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV- 2902
+W + S++ + A TL + V+ + G Y C A ++ G + I V
Sbjct: 272 KWRKVDGSLSPQWTTAEP-------TLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 2903 VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
QP L ++ E DI G ++ G+P+P
Sbjct: 325 AQPEWLK-----VISDTEADI----GSNLRWGCAAAGKPRP 356
Score = 45.6 bits (103), Expect = 0.003
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 20/235 (8%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
V L C+ SPP W +G E+ + +++Q + + + PT D GVY+ A N
Sbjct: 57 VLLACRARASPPATYRWKMNGTEMKLEPG-SRHQLVGGNLVIMNPTKAQDAGVYQCLASN 115
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA-YPSVGVTW-Y 3302
G V + +R EF K HEG + + A YP + W
Sbjct: 116 PVGTVVSREAI-----LRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLL 170
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+ P+ G L +A D G Y+C A++ + ++ S + +
Sbjct: 171 NEFPNFIPTDGRHFVSQTTG--NLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLN 228
Query: 3363 QTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+E + +P + R P + A G V +EC G+P P + W
Sbjct: 229 LAAE---DTRLFAPSIK-------ARFPAETYALVGQQVTLECFAFGNPVPRIKW 273
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 89.0 bits (211), Expect = 3e-16
Identities = 87/337 (25%), Positives = 133/337 (39%), Gaps = 40/337 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP FV P L + ++A C +G PVP V W K+ E+ + + D
Sbjct: 221 ERPSFVK-RPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD-----DH 274
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C A N GKA A L V G P
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--------------------GSEP 314
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY-----DKRRNKYQDEQF 3222
P F ++ RD+ V V C+ G+P P + W ++G + + + +++ Q
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 374
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
L I D G Y N +G++ L V I P G P+ +
Sbjct: 375 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG--PVNQTVAV 432
Query: 3283 D-ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
D +S V P + W +DGV + I L+ +G +++ A + D G YTC
Sbjct: 433 DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVLQIRYAKL--GDTGRYTC 489
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
AS G A+ S +EV + P PP P++
Sbjct: 490 IASTPSGEATWSAYIEV---QEFGVPVQPPRPTDPNL 523
Score = 79.8 bits (188), Expect = 2e-13
Identities = 98/397 (24%), Positives = 156/397 (39%), Gaps = 64/397 (16%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHE 3090
GE+ ++S+ V + D +F P + ++ GE A + C +G P P + W K+G
Sbjct: 115 GEAVSHNASLEVAILRD--DFRQN-PSDVMVVVGEPAVMECQPPRGHPEPTISWKKDGSP 171
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
++++ R+T + T K D G+Y C TN G+ R + V + TV E
Sbjct: 172 LDDKDERITIRGGKLMITYTRKS----DAGKYVCVGTNMVGE-----RESEVAELTVLER 222
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
+ +KR + V D +F C+ G P P V W KD E+
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFK-----------------CEARGDPVPTVRWRKDDGEL-- 263
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+++Y+ HTL+I D G Y A N G L V G P F
Sbjct: 264 --PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE---PPHFV 318
Query: 3271 CGLEPLYKLHE-GDELRISAVVEAYPSVGVTWYRDGVR------LRPSRRAIMTLDRDGQ 3323
++P ++ G + P + W R+G + P + ++ + G
Sbjct: 319 --VKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG- 375
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
+L + V D G Y C N G T +EV TD ++ R PPV+ V
Sbjct: 376 -DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV--TDVIAD-RPPPVIRQGPV----- 426
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ A +G T ++ C G P P + W +D
Sbjct: 427 -------NQTVAVDG-TFVLSCVATGSPVPTILWRKD 455
Score = 77.8 bits (183), Expect = 6e-13
Identities = 102/372 (27%), Positives = 138/372 (37%), Gaps = 63/372 (16%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE-----AGRMTSQFNG-FDCCLT 3110
P L + GE A L C +G+P P + W K G VE + + RM F +
Sbjct: 35 PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIV 94
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ DEG Y C A N G+A ++ +A L+ A + D F
Sbjct: 95 HGRKSRPDEGVYVCVARNYLGEAVSH--------------NASLE---VAILRDD----F 133
Query: 3171 TMRLRDRRVQATYPVRLTCQ-VIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D V P + CQ G P P +SW KDG + R + + L I
Sbjct: 134 RQNPSDVMVVVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK---LMITY 190
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T D G Y N G + P F L + + E +
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCE 245
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
A + P+ V W +D L SR I RD L + VT D G YTC A N VG
Sbjct: 246 ARGDPVPT--VRWRKDDGELPKSRYEI----RDDH-TLKIRKVTAGDMGSYTCVAENMVG 298
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVV 3408
+A S + V SEP P F+ KPR G TV +CE
Sbjct: 299 KAEASATLTV---QVGSEP----------------PHFVVKPRDQVVALGRTVTFQCEAT 339
Query: 3409 GDPKPDVYWLRD 3420
G+P+P ++W R+
Sbjct: 340 GNPQPAIFWRRE 351
Score = 72.9 bits (171), Expect = 2e-11
Identities = 89/353 (25%), Positives = 144/353 (40%), Gaps = 54/353 (15%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL----DNKLKYRKKLVDG-LITLEVLN 2655
+D +G L C PT+ WY+ G + D+ +R L G L L +++
Sbjct: 36 SDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVH 95
Query: 2656 AVPS--DSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
S D Y C N G A+S +A+L E + + F ++ D + V
Sbjct: 96 GRKSRPDEGVYVCVARNYLGEAVSHNASL------EVAILRDDFRQNPSDVMVVVGEPAV 149
Query: 2713 LECR-IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+EC+ RG P P I+W KD P D + + + G +L I D+G Y C N
Sbjct: 150 MECQPPRGHPEPTISWKKDGS--PLDDKDERITIRGG--KLMITYTRKSDAGKYVCVGTN 205
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V RES+V AE T + R S R + + D +
Sbjct: 206 MVGE-----------RESEV------AELTVLERPSFVKRPSNLAVTVDD-------SAE 241
Query: 2832 LQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ E RG P V W ++ + + +R + +TL + VT + G YTC A +
Sbjct: 242 FKCEARGDPVPTVRWRKDDGELPK----SRYEIRDD-HTLKIRKVTAGDMGSYTCVAENM 296
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G + +A +TV + +P V +P +D ++++G + G P+P
Sbjct: 297 VGKAEASATLTV----QVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQP 344
Score = 68.5 bits (160), Expect = 4e-10
Identities = 83/329 (25%), Positives = 135/329 (41%), Gaps = 47/329 (14%)
Query: 2622 DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTS-AN 2680
+PT++W ++G LD+K + R + G + + SD+ +Y C N G + A
Sbjct: 160 EPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRK--SDAGKYVCVGTNMVGERESEVAE 216
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
L V P+F + + ++ +C RG P+P + W KDD ++P RY
Sbjct: 217 LTVLER-------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRY 268
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
+ + D L I T D G+YTC AEN V G+ AE
Sbjct: 269 E---IRDD-HTLKIRKVTAGDMGSYTCVAENMV------------GK----------AEA 302
Query: 2801 TRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR-----SVTE 2854
+ + S PHF D VA G T+ Q E G P + W REG S
Sbjct: 303 SATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQP 362
Query: 2855 VYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
++R V Q L +++V ++ G Y C+ + G++ A + V + +P
Sbjct: 363 PQSSSRFSVSQ-TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV--IADRPPP 419
Query: 2915 IVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ + + ++V +S G P P
Sbjct: 420 VIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Score = 64.5 bits (150), Expect = 6e-09
Identities = 70/265 (26%), Positives = 99/265 (37%), Gaps = 40/265 (15%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-----RRNKYQD 3219
D+PP+ D V P L C+ G P P + WYK GE V DK R
Sbjct: 26 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 3220 EQFHTLEI--APTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D GVY ARN G AVS + L V A + +F +
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV-----AILRDDFRQNPSDV 140
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ + +P ++W +DG L I R G +L + DA
Sbjct: 141 MVVVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGG--KLMITYTRKSDA 196
Query: 3337 GVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA 3395
G Y C +N VG R S ++ V+ + P F+++P +
Sbjct: 197 GKYVCVGTNMVGERESEVAELTVL----------------------ERPSFVKRPSNLAV 234
Query: 3396 REGDTVIIECEVVGDPKPDVYWLRD 3420
D+ +CE GDP P V W +D
Sbjct: 235 TVDDSAEFKCEARGDPVPTVRWRKD 259
Score = 56.0 bits (129), Expect = 2e-06
Identities = 106/478 (22%), Positives = 166/478 (34%), Gaps = 81/478 (16%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL 2634
E S ++E L R S K + +T V+ S + C PTV W ++
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVT----VDDS-AEFKCEARGDPVPTVRWRKD---- 259
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
D +L + + TL++ D Y+C EN G SA L V E PP
Sbjct: 260 DGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE----PP 315
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQ--------IPSDGRYQAFYLA 2746
F RD + +C G P P I W ++ Q S R+
Sbjct: 316 HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG 375
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
D L I N D G Y C+ N V+ +++T +
Sbjct: 376 D----LTITNVQRSDVGYYICQTLN-------------------VAGSIITKAYLEVTDV 412
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARV-FVE 2864
+ P + VA GT L G P + W ++G V+ +++R+ +E
Sbjct: 413 IADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST--QDSRIKQLE 470
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDIL 2924
G+ + + + +T G YTC A + G +A I V
Sbjct: 471 NGVLQIRYAKLGDT--GRYTCIASTPSGEATWSAYIEV---------------------- 506
Query: 2925 ISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
++ + + P +P P +P V D N V+L+W + P +Y +
Sbjct: 507 ----QEFGVPVQPPRPTDPNLIPS-APSKPEVTDVSRNTVTLSWQPNLNSGATPT-SYII 560
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAF-NLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
E++ G+ W + A LK Y F V N YG + SQ S +
Sbjct: 561 EAF--SHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 616
Score = 35.9 bits (79), Expect = 2.6
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS---DGRYQAFYLADG- 2748
PP D L C+ G+P P I W+K +++ + D R L G
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87
Query: 2749 --VCRLAIDNPTPEDSGTYTCKAEN 2771
R+ + D G Y C A N
Sbjct: 88 LFFLRIVHGRKSRPDEGVYVCVARN 112
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 89.0 bits (211), Expect = 3e-16
Identities = 87/337 (25%), Positives = 133/337 (39%), Gaps = 40/337 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP FV P L + ++A C +G PVP V W K+ E+ + + D
Sbjct: 221 ERPSFVK-RPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD-----DH 274
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C A N GKA A L V G P
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--------------------GSEP 314
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY-----DKRRNKYQDEQF 3222
P F ++ RD+ V V C+ G+P P + W ++G + + + +++ Q
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 374
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
L I D G Y N +G++ L V I P G P+ +
Sbjct: 375 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG--PVNQTVAV 432
Query: 3283 D-ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
D +S V P + W +DGV + I L+ +G +++ A + D G YTC
Sbjct: 433 DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVLQIRYAKL--GDTGRYTC 489
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
AS G A+ S +EV + P PP P++
Sbjct: 490 IASTPSGEATWSAYIEV---QEFGVPVQPPRPTDPNL 523
Score = 79.0 bits (186), Expect = 3e-13
Identities = 98/397 (24%), Positives = 155/397 (39%), Gaps = 64/397 (16%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHE 3090
GE+ ++S+ V + D +F P + + GE A + C +G P P + W K+G
Sbjct: 115 GEAVSHNASLEVAILRD--DFRQN-PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSP 171
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
++++ R+T + T K D G+Y C TN G+ R + V + TV E
Sbjct: 172 LDDKDERITIRGGKLMITYTRKS----DAGKYVCVGTNMVGE-----RESEVAELTVLER 222
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
+ +KR + V D +F C+ G P P V W KD E+
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFK-----------------CEARGDPVPTVRWRKDDGEL-- 263
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+++Y+ HTL+I D G Y A N G L V G P F
Sbjct: 264 --PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE---PPHFV 318
Query: 3271 CGLEPLYKLHE-GDELRISAVVEAYPSVGVTWYRDGVR------LRPSRRAIMTLDRDGQ 3323
++P ++ G + P + W R+G + P + ++ + G
Sbjct: 319 --VKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG- 375
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
+L + V D G Y C N G T +EV TD ++ R PPV+ V
Sbjct: 376 -DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV--TDVIAD-RPPPVIRQGPV----- 426
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ A +G T ++ C G P P + W +D
Sbjct: 427 -------NQTVAVDG-TFVLSCVATGSPVPTILWRKD 455
Score = 78.2 bits (184), Expect = 5e-13
Identities = 102/372 (27%), Positives = 138/372 (37%), Gaps = 63/372 (16%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE-----AGRMTSQFNG-FDCCLT 3110
P L + GE A L C +G+P P + W K G VE + + RM F +
Sbjct: 35 PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIV 94
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ DEG Y C A N G+A ++ +A L+ A + D F
Sbjct: 95 HGRKSRPDEGVYVCVARNYLGEAVSH--------------NASLE---VAILRDD----F 133
Query: 3171 TMRLRDRRVQATYPVRLTCQ-VIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D V P + CQ G P P +SW KDG + R + + L I
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK---LMITY 190
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T D G Y N G + P F L + + E +
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCE 245
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
A + P+ V W +D L SR I RD L + VT D G YTC A N VG
Sbjct: 246 ARGDPVPT--VRWRKDDGELPKSRYEI----RDDH-TLKIRKVTAGDMGSYTCVAENMVG 298
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVV 3408
+A S + V SEP P F+ KPR G TV +CE
Sbjct: 299 KAEASATLTV---QVGSEP----------------PHFVVKPRDQVVALGRTVTFQCEAT 339
Query: 3409 GDPKPDVYWLRD 3420
G+P+P ++W R+
Sbjct: 340 GNPQPAIFWRRE 351
Score = 72.1 bits (169), Expect = 3e-11
Identities = 89/353 (25%), Positives = 143/353 (40%), Gaps = 54/353 (15%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL----DNKLKYRKKLVDG-LITLEVLN 2655
+D +G L C PT+ WY+ G + D+ +R L G L L +++
Sbjct: 36 SDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVH 95
Query: 2656 AVPS--DSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
S D Y C N G A+S +A+L E + + F ++ D V
Sbjct: 96 GRKSRPDEGVYVCVARNYLGEAVSHNASL------EVAILRDDFRQNPSDVMVAVGEPAV 149
Query: 2713 LECR-IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+EC+ RG P P I+W KD P D + + + G +L I D+G Y C N
Sbjct: 150 MECQPPRGHPEPTISWKKDGS--PLDDKDERITIRGG--KLMITYTRKSDAGKYVCVGTN 205
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V RES+V AE T + R S R + + D +
Sbjct: 206 MVGE-----------RESEV------AELTVLERPSFVKRPSNLAVTVDD-------SAE 241
Query: 2832 LQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ E RG P V W ++ + + +R + +TL + VT + G YTC A +
Sbjct: 242 FKCEARGDPVPTVRWRKDDGELPK----SRYEIRDD-HTLKIRKVTAGDMGSYTCVAENM 296
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G + +A +TV + +P V +P +D ++++G + G P+P
Sbjct: 297 VGKAEASATLTV----QVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQP 344
Score = 68.5 bits (160), Expect = 4e-10
Identities = 83/329 (25%), Positives = 135/329 (41%), Gaps = 47/329 (14%)
Query: 2622 DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTS-AN 2680
+PT++W ++G LD+K + R + G + + SD+ +Y C N G + A
Sbjct: 160 EPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRK--SDAGKYVCVGTNMVGERESEVAE 216
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
L V P+F + + ++ +C RG P+P + W KDD ++P RY
Sbjct: 217 LTVLER-------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRY 268
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
+ + D L I T D G+YTC AEN V G+ AE
Sbjct: 269 E---IRDD-HTLKIRKVTAGDMGSYTCVAENMV------------GK----------AEA 302
Query: 2801 TRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR-----SVTE 2854
+ + S PHF D VA G T+ Q E G P + W REG S
Sbjct: 303 SATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQP 362
Query: 2855 VYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
++R V Q L +++V ++ G Y C+ + G++ A + V + +P
Sbjct: 363 PQSSSRFSVSQ-TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV--IADRPPP 419
Query: 2915 IVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ + + ++V +S G P P
Sbjct: 420 VIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Score = 63.7 bits (148), Expect = 1e-08
Identities = 70/265 (26%), Positives = 98/265 (36%), Gaps = 40/265 (15%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-----RRNKYQD 3219
D+PP+ D V P L C+ G P P + WYK GE V DK R
Sbjct: 26 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 3220 EQFHTLEI--APTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D GVY ARN G AVS + L V A + +F +
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV-----AILRDDFRQNPSDV 140
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ +P ++W +DG L I R G +L + DA
Sbjct: 141 MVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGG--KLMITYTRKSDA 196
Query: 3337 GVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA 3395
G Y C +N VG R S ++ V+ + P F+++P +
Sbjct: 197 GKYVCVGTNMVGERESEVAELTVL----------------------ERPSFVKRPSNLAV 234
Query: 3396 REGDTVIIECEVVGDPKPDVYWLRD 3420
D+ +CE GDP P V W +D
Sbjct: 235 TVDDSAEFKCEARGDPVPTVRWRKD 259
Score = 56.0 bits (129), Expect = 2e-06
Identities = 106/478 (22%), Positives = 166/478 (34%), Gaps = 81/478 (16%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL 2634
E S ++E L R S K + +T V+ S + C PTV W ++
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVT----VDDS-AEFKCEARGDPVPTVRWRKD---- 259
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
D +L + + TL++ D Y+C EN G SA L V E PP
Sbjct: 260 DGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE----PP 315
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQ--------IPSDGRYQAFYLA 2746
F RD + +C G P P I W ++ Q S R+
Sbjct: 316 HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG 375
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
D L I N D G Y C+ N V+ +++T +
Sbjct: 376 D----LTITNVQRSDVGYYICQTLN-------------------VAGSIITKAYLEVTDV 412
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARV-FVE 2864
+ P + VA GT L G P + W ++G V+ +++R+ +E
Sbjct: 413 IADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST--QDSRIKQLE 470
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDIL 2924
G+ + + + +T G YTC A + G +A I V
Sbjct: 471 NGVLQIRYAKLGDT--GRYTCIASTPSGEATWSAYIEV---------------------- 506
Query: 2925 ISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
++ + + P +P P +P V D N V+L+W + P +Y +
Sbjct: 507 ----QEFGVPVQPPRPTDPNLIPS-APSKPEVTDVSRNTVTLSWQPNLNSGATPT-SYII 560
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAF-NLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
E++ G+ W + A LK Y F V N YG + SQ S +
Sbjct: 561 EAF--SHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 616
Score = 35.9 bits (79), Expect = 2.6
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS---DGRYQAFYLADG- 2748
PP D L C+ G+P P I W+K +++ + D R L G
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87
Query: 2749 --VCRLAIDNPTPEDSGTYTCKAEN 2771
R+ + D G Y C A N
Sbjct: 88 LFFLRIVHGRKSRPDEGVYVCVARN 112
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 89.0 bits (211), Expect = 3e-16
Identities = 87/337 (25%), Positives = 133/337 (39%), Gaps = 40/337 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP FV P L + ++A C +G PVP V W K+ E+ + + D
Sbjct: 221 ERPSFVK-RPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD-----DH 274
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C A N GKA A L V G P
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--------------------GSEP 314
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY-----DKRRNKYQDEQF 3222
P F ++ RD+ V V C+ G+P P + W ++G + + + +++ Q
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 374
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
L I D G Y N +G++ L V I P G P+ +
Sbjct: 375 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG--PVNQTVAV 432
Query: 3283 D-ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
D +S V P + W +DGV + I L+ +G +++ A + D G YTC
Sbjct: 433 DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVLQIRYAKL--GDTGRYTC 489
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
AS G A+ S +EV + P PP P++
Sbjct: 490 IASTPSGEATWSAYIEV---QEFGVPVQPPRPTDPNL 523
Score = 79.0 bits (186), Expect = 3e-13
Identities = 98/397 (24%), Positives = 155/397 (39%), Gaps = 64/397 (16%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHE 3090
GE+ ++S+ V + D +F P + + GE A + C +G P P + W K+G
Sbjct: 115 GEAVSHNASLEVAILRD--DFRQN-PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSP 171
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
++++ R+T + T K D G+Y C TN G+ R + V + TV E
Sbjct: 172 LDDKDERITIRGGKLMITYTRKS----DAGKYVCVGTNMVGE-----RESEVAELTVLER 222
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
+ +KR + V D +F C+ G P P V W KD E+
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFK-----------------CEARGDPVPTVRWRKDDGEL-- 263
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+++Y+ HTL+I D G Y A N G L V G P F
Sbjct: 264 --PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE---PPHFV 318
Query: 3271 CGLEPLYKLHE-GDELRISAVVEAYPSVGVTWYRDGVR------LRPSRRAIMTLDRDGQ 3323
++P ++ G + P + W R+G + P + ++ + G
Sbjct: 319 --VKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG- 375
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
+L + V D G Y C N G T +EV TD ++ R PPV+ V
Sbjct: 376 -DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV--TDVIAD-RPPPVIRQGPV----- 426
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ A +G T ++ C G P P + W +D
Sbjct: 427 -------NQTVAVDG-TFVLSCVATGSPVPTILWRKD 455
Score = 78.2 bits (184), Expect = 5e-13
Identities = 102/372 (27%), Positives = 138/372 (37%), Gaps = 63/372 (16%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE-----AGRMTSQFNG-FDCCLT 3110
P L + GE A L C +G+P P + W K G VE + + RM F +
Sbjct: 35 PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIV 94
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ DEG Y C A N G+A ++ +A L+ A + D F
Sbjct: 95 HGRKSRPDEGVYVCVARNYLGEAVSH--------------NASLE---VAILRDD----F 133
Query: 3171 TMRLRDRRVQATYPVRLTCQ-VIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D V P + CQ G P P +SW KDG + R + + L I
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK---LMITY 190
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T D G Y N G + P F L + + E +
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCE 245
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
A + P+ V W +D L SR I RD L + VT D G YTC A N VG
Sbjct: 246 ARGDPVPT--VRWRKDDGELPKSRYEI----RDDH-TLKIRKVTAGDMGSYTCVAENMVG 298
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVV 3408
+A S + V SEP P F+ KPR G TV +CE
Sbjct: 299 KAEASATLTV---QVGSEP----------------PHFVVKPRDQVVALGRTVTFQCEAT 339
Query: 3409 GDPKPDVYWLRD 3420
G+P+P ++W R+
Sbjct: 340 GNPQPAIFWRRE 351
Score = 72.1 bits (169), Expect = 3e-11
Identities = 89/353 (25%), Positives = 143/353 (40%), Gaps = 54/353 (15%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL----DNKLKYRKKLVDG-LITLEVLN 2655
+D +G L C PT+ WY+ G + D+ +R L G L L +++
Sbjct: 36 SDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVH 95
Query: 2656 AVPS--DSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
S D Y C N G A+S +A+L E + + F ++ D V
Sbjct: 96 GRKSRPDEGVYVCVARNYLGEAVSHNASL------EVAILRDDFRQNPSDVMVAVGEPAV 149
Query: 2713 LECR-IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+EC+ RG P P I+W KD P D + + + G +L I D+G Y C N
Sbjct: 150 MECQPPRGHPEPTISWKKDGS--PLDDKDERITIRGG--KLMITYTRKSDAGKYVCVGTN 205
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V RES+V AE T + R S R + + D +
Sbjct: 206 MVGE-----------RESEV------AELTVLERPSFVKRPSNLAVTVDD-------SAE 241
Query: 2832 LQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ E RG P V W ++ + + +R + +TL + VT + G YTC A +
Sbjct: 242 FKCEARGDPVPTVRWRKDDGELPK----SRYEIRDD-HTLKIRKVTAGDMGSYTCVAENM 296
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G + +A +TV + +P V +P +D ++++G + G P+P
Sbjct: 297 VGKAEASATLTV----QVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQP 344
Score = 68.5 bits (160), Expect = 4e-10
Identities = 83/329 (25%), Positives = 135/329 (41%), Gaps = 47/329 (14%)
Query: 2622 DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTS-AN 2680
+PT++W ++G LD+K + R + G + + SD+ +Y C N G + A
Sbjct: 160 EPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRK--SDAGKYVCVGTNMVGERESEVAE 216
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
L V P+F + + ++ +C RG P+P + W KDD ++P RY
Sbjct: 217 LTVLER-------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRY 268
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
+ + D L I T D G+YTC AEN V G+ AE
Sbjct: 269 E---IRDD-HTLKIRKVTAGDMGSYTCVAENMV------------GK----------AEA 302
Query: 2801 TRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR-----SVTE 2854
+ + S PHF D VA G T+ Q E G P + W REG S
Sbjct: 303 SATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQP 362
Query: 2855 VYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
++R V Q L +++V ++ G Y C+ + G++ A + V + +P
Sbjct: 363 PQSSSRFSVSQ-TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV--IADRPPP 419
Query: 2915 IVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ + + ++V +S G P P
Sbjct: 420 VIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Score = 63.7 bits (148), Expect = 1e-08
Identities = 70/265 (26%), Positives = 98/265 (36%), Gaps = 40/265 (15%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-----RRNKYQD 3219
D+PP+ D V P L C+ G P P + WYK GE V DK R
Sbjct: 26 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 3220 EQFHTLEI--APTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D GVY ARN G AVS + L V A + +F +
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV-----AILRDDFRQNPSDV 140
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ +P ++W +DG L I R G +L + DA
Sbjct: 141 MVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGG--KLMITYTRKSDA 196
Query: 3337 GVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA 3395
G Y C +N VG R S ++ V+ + P F+++P +
Sbjct: 197 GKYVCVGTNMVGERESEVAELTVL----------------------ERPSFVKRPSNLAV 234
Query: 3396 REGDTVIIECEVVGDPKPDVYWLRD 3420
D+ +CE GDP P V W +D
Sbjct: 235 TVDDSAEFKCEARGDPVPTVRWRKD 259
Score = 56.0 bits (129), Expect = 2e-06
Identities = 106/478 (22%), Positives = 166/478 (34%), Gaps = 81/478 (16%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL 2634
E S ++E L R S K + +T V+ S + C PTV W ++
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVT----VDDS-AEFKCEARGDPVPTVRWRKD---- 259
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
D +L + + TL++ D Y+C EN G SA L V E PP
Sbjct: 260 DGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE----PP 315
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQ--------IPSDGRYQAFYLA 2746
F RD + +C G P P I W ++ Q S R+
Sbjct: 316 HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG 375
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
D L I N D G Y C+ N V+ +++T +
Sbjct: 376 D----LTITNVQRSDVGYYICQTLN-------------------VAGSIITKAYLEVTDV 412
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARV-FVE 2864
+ P + VA GT L G P + W ++G V+ +++R+ +E
Sbjct: 413 IADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST--QDSRIKQLE 470
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDIL 2924
G+ + + + +T G YTC A + G +A I V
Sbjct: 471 NGVLQIRYAKLGDT--GRYTCIASTPSGEATWSAYIEV---------------------- 506
Query: 2925 ISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
++ + + P +P P +P V D N V+L+W + P +Y +
Sbjct: 507 ----QEFGVPVQPPRPTDPNLIPS-APSKPEVTDVSRNTVTLSWQPNLNSGATPT-SYII 560
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAF-NLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
E++ G+ W + A LK Y F V N YG + SQ S +
Sbjct: 561 EAF--SHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 616
Score = 35.9 bits (79), Expect = 2.6
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS---DGRYQAFYLADG- 2748
PP D L C+ G+P P I W+K +++ + D R L G
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87
Query: 2749 --VCRLAIDNPTPEDSGTYTCKAEN 2771
R+ + D G Y C A N
Sbjct: 88 LFFLRIVHGRKSRPDEGVYVCVARN 112
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 88.6 bits (210), Expect = 3e-16
Identities = 86/314 (27%), Positives = 127/314 (40%), Gaps = 39/314 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G++ L C +G P P + W K+G ++E+E F+ LTIK ++ +DE Y C
Sbjct: 228 GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYIC 287
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G+ L V + + VE Q M L ++
Sbjct: 288 IAENKAGEQDATIHLKVFA------------KPKITYVEN----QTAMELEEQ------- 324
Query: 3185 VRLTCQVIGSPPPKVSWYKD-----GEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
V LTC+ G P P ++W EE D + +L + D G Y
Sbjct: 325 VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 384
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
TA N G S L V AP+ G +Y EG+++ I+ V AYPS +
Sbjct: 385 CTASNTIGQDSQSMYLEVQ------YAPKLQ-GPVAVYTW-EGNQVNITCEVFAYPSATI 436
Query: 3300 TWYRDGVRLRPSRRA-IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+W+RDG L S + I + L + + D G Y CTA N +G+ S + +
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESL--EFIL 494
Query: 3359 IGTDQTSEPRIPPV 3372
+ D S P I V
Sbjct: 495 VQADTPSSPSIDQV 508
Score = 68.5 bits (160), Expect = 4e-10
Identities = 71/322 (22%), Positives = 130/322 (40%), Gaps = 43/322 (13%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVP 2658
+ + TA G V L C +PT++W ++G ++ + K + D L +
Sbjct: 220 IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDK 279
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
+D AEY C EN+ G + +LKV+ P T T E ++ L C
Sbjct: 280 NDEAEYICIAENKAGEQDATIHLKVFAK-------PKITYVENQTAMELEEQVTLTCEAS 332
Query: 2719 GQPLPKITWFKDDKQIPSDGR----YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
G P+P ITW + I S+ + + V L + + D+G Y C A N++
Sbjct: 333 GDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 392
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
D + ++ E Q +P + + +A + E G + +
Sbjct: 393 QDSQSMYL-----EVQYAPKL----QGPVAVYTWE-----------------GNQVNITC 426
Query: 2835 EIRGCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
E+ P+ + W R+G+ + + Y N +++ L ++ +E + G Y C A + G
Sbjct: 427 EVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIG 486
Query: 2893 NVDMNAAITVVQPSDLDGKPAV 2914
+ +VQ +D P++
Sbjct: 487 QESLE--FILVQ-ADTPSSPSI 505
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/371 (22%), Positives = 135/371 (36%), Gaps = 57/371 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVP-GVVWMK-NGHEVEEEAGRMTSQFNG-FDCCL 3109
VDI+P Q +I GE+ C V G + W NG ++ R++ +N L
Sbjct: 22 VDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTL 81
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
TI + NIDD G Y C T G S EA +K + + PQ
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSES--------------EATVNVKIFQKLMFKNAPTPQ 127
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D + C V+ S PP + W G +V+ K+ ++ + L+I
Sbjct: 128 EFREGED--------AVIVCDVVSSLPPTIIWKHKGRDVIL-KKDVRFIVLSNNYLQIRG 178
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLYK--LHEGDELR 3286
D G Y R + G + K I+ V P + + + G +
Sbjct: 179 IKKTDEGTYRCEGRILAR------GEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVT 232
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ E +P ++W +DG ++ + D +L + V D Y C A N+
Sbjct: 233 LVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENK 292
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
G + ++V ++P+I ++ + E E V + CE
Sbjct: 293 AGEQDATIHLKVF-----AKPKI---------------TYVENQTAMELEE--QVTLTCE 330
Query: 3407 VVGDPKPDVYW 3417
GDP P + W
Sbjct: 331 ASGDPIPSITW 341
Score = 58.4 bits (135), Expect = 4e-07
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 14/193 (7%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLI 2649
+K +F T + EG + C V+SS PT+ W G V+L +++ +V
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRF---IVLSNN 172
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHL 2706
L++ +D Y C G I + +PPT + T +L
Sbjct: 173 YLQIRGIKKTDEGTYRC-----EGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANL 227
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
++ + L C G P P ++W KD +QI + + + +D +L I D Y
Sbjct: 228 GQS-VTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 2767 CKAENSVWTDQIT 2779
C AEN T
Sbjct: 287 CIAENKAGEQDAT 299
Score = 53.2 bits (122), Expect = 2e-05
Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 21/191 (10%)
Query: 2598 TFLTDRTAVE-GSRVKLTCSVISSSDPTVTWY---RN----GVLLDNKLKYRKKLVDGLI 2649
T++ ++TA+E +V LTC P++TW RN LD + R +
Sbjct: 311 TYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSL 370
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAE 2708
TL+ + +D+ EY CT N G S S L+V Y P+ +
Sbjct: 371 TLKSIQY--TDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---------VYTWEG 419
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQ-AFYLADGVCRLAIDNPTPEDSGTYTC 2767
N++ + C + P I+WF+D + +PS Y L + + D G Y C
Sbjct: 420 NQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNC 479
Query: 2768 KAENSVWTDQI 2778
A N + + +
Sbjct: 480 TAVNRIGQESL 490
Score = 43.2 bits (97), Expect = 0.017
Identities = 71/338 (21%), Positives = 126/338 (37%), Gaps = 50/338 (14%)
Query: 2615 CSVISSS-DPTVTWYR-NGVLLDNKLKYRKKLV---DGLITLEVLNAVPSDSAEYSCTVE 2669
C V + D ++W+ NG L + R +V D TL + NA D+ Y C V
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPN-QQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVT 99
Query: 2670 NENGAIS-TSANLKVYPS--FEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
E+G+ S + N+K++ F+ +P P F + V+ C + P I
Sbjct: 100 GEDGSESEATVNVKIFQKLMFKNAPTPQEFREG---------EDAVIVCDVVSSLPPTII 150
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W + + + L++ L I D GTY C+ + +NF
Sbjct: 151 WKHKGRDVILKKDVRFIVLSNNY--LQIRGIKKTDEGTYRCEGRILARGE-----INF-- 201
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEW 2845
++ QV +V T ARQ++ + + G +T L + G P + W
Sbjct: 202 KDIQV---IVNVPPTIQARQNIVNATANLGQSVT-----------LVCDAEGFPEPTMSW 247
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
++G + + + + L + V + + Y C A + G D + V
Sbjct: 248 TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVF-- 305
Query: 2906 SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP + E + + E + ++ G+P P
Sbjct: 306 ----AKPKITY--VENQTAMELEEQVTLTCEASGDPIP 337
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 88.6 bits (210), Expect = 3e-16
Identities = 86/314 (27%), Positives = 127/314 (40%), Gaps = 39/314 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G++ L C +G P P + W K+G ++E+E F+ LTIK ++ +DE Y C
Sbjct: 228 GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYIC 287
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G+ L V + + VE Q M L ++
Sbjct: 288 IAENKAGEQDATIHLKVFA------------KPKITYVEN----QTAMELEEQ------- 324
Query: 3185 VRLTCQVIGSPPPKVSWYKD-----GEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
V LTC+ G P P ++W EE D + +L + D G Y
Sbjct: 325 VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 384
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
TA N G S L V AP+ G +Y EG+++ I+ V AYPS +
Sbjct: 385 CTASNTIGQDSQSMYLEVQ------YAPKLQ-GPVAVYTW-EGNQVNITCEVFAYPSATI 436
Query: 3300 TWYRDGVRLRPSRRA-IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+W+RDG L S + I + L + + D G Y CTA N +G+ S + +
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESL--EFIL 494
Query: 3359 IGTDQTSEPRIPPV 3372
+ D S P I V
Sbjct: 495 VQADTPSSPSIDQV 508
Score = 68.5 bits (160), Expect = 4e-10
Identities = 71/322 (22%), Positives = 130/322 (40%), Gaps = 43/322 (13%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVP 2658
+ + TA G V L C +PT++W ++G ++ + K + D L +
Sbjct: 220 IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDK 279
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
+D AEY C EN+ G + +LKV+ P T T E ++ L C
Sbjct: 280 NDEAEYICIAENKAGEQDATIHLKVFAK-------PKITYVENQTAMELEEQVTLTCEAS 332
Query: 2719 GQPLPKITWFKDDKQIPSDGR----YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
G P+P ITW + I S+ + + V L + + D+G Y C A N++
Sbjct: 333 GDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 392
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
D + ++ E Q +P + + +A + E G + +
Sbjct: 393 QDSQSMYL-----EVQYAPKL----QGPVAVYTWE-----------------GNQVNITC 426
Query: 2835 EIRGCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
E+ P+ + W R+G+ + + Y N +++ L ++ +E + G Y C A + G
Sbjct: 427 EVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIG 486
Query: 2893 NVDMNAAITVVQPSDLDGKPAV 2914
+ +VQ +D P++
Sbjct: 487 QESLE--FILVQ-ADTPSSPSI 505
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/371 (22%), Positives = 135/371 (36%), Gaps = 57/371 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVP-GVVWMK-NGHEVEEEAGRMTSQFNG-FDCCL 3109
VDI+P Q +I GE+ C V G + W NG ++ R++ +N L
Sbjct: 22 VDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTL 81
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
TI + NIDD G Y C T G S EA +K + + PQ
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSES--------------EATVNVKIFQKLMFKNAPTPQ 127
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D + C V+ S PP + W G +V+ K+ ++ + L+I
Sbjct: 128 EFREGED--------AVIVCDVVSSLPPTIIWKHKGRDVIL-KKDVRFIVLSNNYLQIRG 178
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLYK--LHEGDELR 3286
D G Y R + G + K I+ V P + + + G +
Sbjct: 179 IKKTDEGTYRCEGRILAR------GEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVT 232
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ E +P ++W +DG ++ + D +L + V D Y C A N+
Sbjct: 233 LVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENK 292
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
G + ++V ++P+I ++ + E E V + CE
Sbjct: 293 AGEQDATIHLKVF-----AKPKI---------------TYVENQTAMELEE--QVTLTCE 330
Query: 3407 VVGDPKPDVYW 3417
GDP P + W
Sbjct: 331 ASGDPIPSITW 341
Score = 58.4 bits (135), Expect = 4e-07
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 14/193 (7%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLI 2649
+K +F T + EG + C V+SS PT+ W G V+L +++ +V
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRF---IVLSNN 172
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHL 2706
L++ +D Y C G I + +PPT + T +L
Sbjct: 173 YLQIRGIKKTDEGTYRC-----EGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANL 227
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
++ + L C G P P ++W KD +QI + + + +D +L I D Y
Sbjct: 228 GQS-VTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 2767 CKAENSVWTDQIT 2779
C AEN T
Sbjct: 287 CIAENKAGEQDAT 299
Score = 53.2 bits (122), Expect = 2e-05
Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 21/191 (10%)
Query: 2598 TFLTDRTAVE-GSRVKLTCSVISSSDPTVTWY---RN----GVLLDNKLKYRKKLVDGLI 2649
T++ ++TA+E +V LTC P++TW RN LD + R +
Sbjct: 311 TYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSL 370
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAE 2708
TL+ + +D+ EY CT N G S S L+V Y P+ +
Sbjct: 371 TLKSIQY--TDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---------VYTWEG 419
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQ-AFYLADGVCRLAIDNPTPEDSGTYTC 2767
N++ + C + P I+WF+D + +PS Y L + + D G Y C
Sbjct: 420 NQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNC 479
Query: 2768 KAENSVWTDQI 2778
A N + + +
Sbjct: 480 TAVNRIGQESL 490
Score = 43.2 bits (97), Expect = 0.017
Identities = 71/338 (21%), Positives = 126/338 (37%), Gaps = 50/338 (14%)
Query: 2615 CSVISSS-DPTVTWYR-NGVLLDNKLKYRKKLV---DGLITLEVLNAVPSDSAEYSCTVE 2669
C V + D ++W+ NG L + R +V D TL + NA D+ Y C V
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPN-QQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVT 99
Query: 2670 NENGAIS-TSANLKVYPS--FEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
E+G+ S + N+K++ F+ +P P F + V+ C + P I
Sbjct: 100 GEDGSESEATVNVKIFQKLMFKNAPTPQEFREG---------EDAVIVCDVVSSLPPTII 150
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W + + + L++ L I D GTY C+ + +NF
Sbjct: 151 WKHKGRDVILKKDVRFIVLSNNY--LQIRGIKKTDEGTYRCEGRILARGE-----INF-- 201
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEW 2845
++ QV +V T ARQ++ + + G +T L + G P + W
Sbjct: 202 KDIQV---IVNVPPTIQARQNIVNATANLGQSVT-----------LVCDAEGFPEPTMSW 247
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
++G + + + + L + V + + Y C A + G D + V
Sbjct: 248 TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVF-- 305
Query: 2906 SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP + E + + E + ++ G+P P
Sbjct: 306 ----AKPKITY--VENQTAMELEEQVTLTCEASGDPIP 337
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase protein.
Length = 1463
Score = 88.6 bits (210), Expect = 3e-16
Identities = 84/343 (24%), Positives = 141/343 (41%), Gaps = 45/343 (13%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
N ++ ++ ++ RN G E+ S+ + +P FV I P ++L G + L
Sbjct: 294 NTRESDQGVYQCMARNSAG--EAKTQSAMLRYSSLPAKPSFV-IQPQDTEVLIGTSTTLE 350
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C G P P + W ++ + +E + R + +G L +++I D GR++C A N+HG
Sbjct: 351 CMATGHPHPLITWTRD-NGLELDGSRHVATSSG----LYLQNITQRDHGRFTCHANNSHG 405
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
A + V PPQFT+ +D+ V + V C+
Sbjct: 406 TVQAAANIIVQA-----------------------PPQFTVTPKDQVVLEEHAVEWLCEA 442
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
G+PPP + W K G ++ + + TL I D G YE A ++ G
Sbjct: 443 DGNPPPVIVWTKTGGQLPVEGQHTVLSS---GTLRIDRAAQHDQGQYECQAVSSLGVKKV 499
Query: 3252 HCGLVV-DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRP 3310
L V K + + L + G + IS + P +TW ++GV++
Sbjct: 500 SVQLTVKPKALAVFTQ------LPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITE 553
Query: 3311 SRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S + +D +G + + A D G Y C A N G A T+
Sbjct: 554 SGK--FHVDDEGTLTIYDAGFP--DQGRYECVARNSFGLAVTN 592
Score = 85.8 bits (203), Expect = 2e-15
Identities = 93/337 (27%), Positives = 130/337 (38%), Gaps = 45/337 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ V TC + P + W N LD + R + D TL + N SD Y C
Sbjct: 248 GNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDG-TLMIRNTRESDQGVYQCM 306
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N G T + + Y S P P+F +DT L LEC G P P ITW
Sbjct: 307 ARNSAGEAKTQSAMLRYSSL---PAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITW 363
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
+D+ R+ A + G L + N T D G +TC A NS T
Sbjct: 364 TRDNGLELDGSRHVA--TSSG---LYLQNITQRDHGRFTCHANNSHGT------------ 406
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWL 2846
Q + N++ P F D V + E G P V W
Sbjct: 407 -VQAAANIIVQAP------------PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWT 453
Query: 2847 REGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPS 2906
+ G + + G TL + + + G Y C+A S+ G ++ +TV +P
Sbjct: 454 KTGGQLP--VEGQHTVLSSG--TLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTV-KPK 508
Query: 2907 DLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
L AV P+ D + VG++INIS QGEP+P
Sbjct: 509 AL----AVFTQLPQ-DTSVEVGKNINISCHAQGEPQP 540
Score = 76.2 bits (179), Expect = 2e-12
Identities = 81/312 (25%), Positives = 123/312 (39%), Gaps = 45/312 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITL 2651
KP F D + G+ L C P +TW R NG+ LD + V L
Sbjct: 329 KPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGS-----RHVATSSGL 383
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ N D ++C N +G + +AN+ V PP FT + +D L E+ +
Sbjct: 384 YLQNITQRDHGRFTCHANNSHGTVQAAANIIVQA-------PPQFTVTPKDQVVLEEHAV 436
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C G P P I W K Q+P +G++ L+ G R ID D G Y C+A +
Sbjct: 437 EWLCEADGNPPPVIVWTKTGGQLPVEGQHTV--LSSGTLR--IDRAAQHDQGQYECQAVS 492
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
S+ +++ V T V P + F + D V G I
Sbjct: 493 SLGVKKVS--VQLT-----VKPKALAV----------------FTQLPQDTSVEVGKNIN 529
Query: 2832 LQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ +G P + W +EG +TE + + V+ TL + D + G Y C A ++
Sbjct: 530 ISCHAQGEPQPIITWNKEGVQITE---SGKFHVDDE-GTLTIYDAGFPDQGRYECVARNS 585
Query: 2891 HGNVDMNAAITV 2902
G N +TV
Sbjct: 586 FGLAVTNMFLTV 597
Score = 72.9 bits (171), Expect = 2e-11
Identities = 81/368 (22%), Positives = 143/368 (38%), Gaps = 56/368 (15%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +++ +G T TC +G P P ++W+ N H ++ E + F+ D L I++
Sbjct: 240 PQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFD--DGTLMIRNTRE 297
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D+G Y C A N+ G+A T + + R S + P F ++ +D
Sbjct: 298 SDQGVYQCMARNSAGEAKT---------------QSAMLRYSSLPAK----PSFVIQPQD 338
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P ++W +D + D R+ + I D G
Sbjct: 339 TEVLIGTSTTLECMATGHPHPLITWTRD-NGLELDGSRHVATSSGLYLQNITQR---DHG 394
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
+ A N+ G V ++V + V P+ LE H + L + P
Sbjct: 395 RFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEE----HAVEWL---CEADGNPP 447
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
+ W + G +L + T+ G + + AA D G Y C A + +G V
Sbjct: 448 PVIVWTKTGGQLPVEGQ--HTVLSSGTLRIDRAA--QHDQGQYECQAVSSLG-------V 496
Query: 3357 EVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVY 3416
+ + T +P+ V F + P+ + G + I C G+P+P +
Sbjct: 497 KKVSVQLTVKPKALAV-------------FTQLPQDTSVEVGKNINISCHAQGEPQPIIT 543
Query: 3417 WLRDFLKV 3424
W ++ +++
Sbjct: 544 WNKEGVQI 551
Score = 65.7 bits (153), Expect = 3e-09
Identities = 66/274 (24%), Positives = 100/274 (36%), Gaps = 12/274 (4%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ D+ +E V+ C + P + W + G L + ++ L G TL +
Sbjct: 419 PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTV-LSSG--TLRI 475
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
A D +Y C + G S L V P A FT+ +DT + +
Sbjct: 476 DRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALA-----VFTQLPQDTSVEVGKNINI 530
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C +G+P P ITW K+ QI G++ D L I + D G Y C A NS
Sbjct: 531 SCHAQGEPQPIITWNKEGVQITESGKFH----VDDEGTLTIYDAGFPDQGRYECVARNSF 586
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
F+ T + + + + A Q ++S L + + Q
Sbjct: 587 GLAVTNMFLTVTAIQGRQAGDDFVESSILDAVQRVDSAINSTRRHLFSQKPHTSSDLLAQ 646
Query: 2834 VEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGL 2867
P VE R G + R V+QGL
Sbjct: 647 FHYPRDPLIVEMARAGEIFEHTLQLIRERVKQGL 680
Score = 64.1 bits (149), Expect = 8e-09
Identities = 65/255 (25%), Positives = 100/255 (39%), Gaps = 37/255 (14%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGE--EVVYDKRRNKYQDEQFHTL 3225
P+ T +D V + V TC+ G+P P++ W + ++ D R N + D TL
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDD---GTL 290
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I T D GVY+ ARN++G ++ + A P F + L G
Sbjct: 291 MIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPA--KPSFVIQPQDTEVL-IGTST 347
Query: 3286 RISAVVEAYPSVGVTWYRD-GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +P +TW RD G+ L SR + L L +T RD G +TC A+
Sbjct: 348 TLECMATGHPHPLITWTRDNGLELDGSRHVATSSG------LYLQNITQRDHGRFTCHAN 401
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
N G + + +V +P P F P+ E V
Sbjct: 402 NSHGTVQAAANI---------------IVQAP-------PQFTVTPKDQVVLEEHAVEWL 439
Query: 3405 CEVVGDPKPDVYWLR 3419
CE G+P P + W +
Sbjct: 440 CEADGNPPPVIVWTK 454
Score = 58.8 bits (136), Expect = 3e-07
Identities = 52/208 (25%), Positives = 83/208 (39%), Gaps = 29/208 (13%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P+F + P +L C G P P +VW K G ++ E G+ T +G L
Sbjct: 419 PQFT-VTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVE-GQHTVLSSG---TL 473
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I D+G+Y C+A ++ G +L V + ++ V
Sbjct: 474 RIDRAAQHDQGQYECQAVSSLGVKKVSVQLTV--------------KPKALAV------- 512
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
FT +D V+ + ++C G P P ++W K+G ++ K+ + TL I
Sbjct: 513 FTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQIT---ESGKFHVDDEGTLTIYD 569
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
D G YE ARN+ G + L V
Sbjct: 570 AGFPDQGRYECVARNSFGLAVTNMFLTV 597
Score = 51.6 bits (118), Expect = 5e-05
Identities = 55/220 (25%), Positives = 85/220 (38%), Gaps = 29/220 (13%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P T +D + N + CR G P P+I W ++ + + + DG L
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGT--LM 291
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRP 2813
I N D G Y C A NS E++ ++ + R S +P
Sbjct: 292 IRNTRESDQGVYQCMARNS-------------AGEAKT--------QSAMLRYSSLPAKP 330
Query: 2814 HFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
F D +V G + L+ G P + W R+ + E+ + V GLY L
Sbjct: 331 SFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRD--NGLELDGSRHVATSSGLY---L 385
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKP 2912
++T+ + G +TC A ++HG V A I V P P
Sbjct: 386 QNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTP 425
Score = 40.3 bits (90), Expect = 0.12
Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 9/125 (7%)
Query: 2821 DYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTET 2878
D +V G T+ G P + W+ S+ ++ + R+ V + G TL + + E+
Sbjct: 242 DVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSL-DLEDDTRLNVFDDG--TLMIRNTRES 298
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQ 2938
+ G+Y C A ++ G +A +++ S L KP+ ++ + ++LI G +
Sbjct: 299 DQGVYQCMARNSAGEAKTQSA--MLRYSSLPAKPSFVIQPQDTEVLI--GTSTTLECMAT 354
Query: 2939 GEPKP 2943
G P P
Sbjct: 355 GHPHP 359
Score = 35.5 bits (78), Expect = 3.4
Identities = 12/39 (30%), Positives = 21/39 (53%)
Query: 3382 KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ P +P+ E G+TV C G+PKP++ W+ +
Sbjct: 232 QSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHN 270
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 88.6 bits (210), Expect = 3e-16
Identities = 86/314 (27%), Positives = 127/314 (40%), Gaps = 39/314 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G++ L C +G P P + W K+G ++E+E F+ LTIK ++ +DE Y C
Sbjct: 309 GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYIC 368
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G+ L V + + VE Q M L ++
Sbjct: 369 IAENKAGEQDATIHLKVFA------------KPKITYVEN----QTAMELEEQ------- 405
Query: 3185 VRLTCQVIGSPPPKVSWYKD-----GEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
V LTC+ G P P ++W EE D + +L + D G Y
Sbjct: 406 VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 465
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
TA N G S L V AP+ G +Y EG+++ I+ V AYPS +
Sbjct: 466 CTASNTIGQDSQSMYLEVQ------YAPKLQ-GPVAVYTW-EGNQVNITCEVFAYPSATI 517
Query: 3300 TWYRDGVRLRPSRRA-IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+W+RDG L S + I + L + + D G Y CTA N +G+ S + +
Sbjct: 518 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESL--EFIL 575
Query: 3359 IGTDQTSEPRIPPV 3372
+ D S P I V
Sbjct: 576 VQADTPSSPSIDQV 589
Score = 68.5 bits (160), Expect = 4e-10
Identities = 71/322 (22%), Positives = 130/322 (40%), Gaps = 43/322 (13%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVP 2658
+ + TA G V L C +PT++W ++G ++ + K + D L +
Sbjct: 301 IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDK 360
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
+D AEY C EN+ G + +LKV+ P T T E ++ L C
Sbjct: 361 NDEAEYICIAENKAGEQDATIHLKVFAK-------PKITYVENQTAMELEEQVTLTCEAS 413
Query: 2719 GQPLPKITWFKDDKQIPSDGR----YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
G P+P ITW + I S+ + + V L + + D+G Y C A N++
Sbjct: 414 GDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 473
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
D + ++ E Q +P + + +A + E G + +
Sbjct: 474 QDSQSMYL-----EVQYAPKL----QGPVAVYTWE-----------------GNQVNITC 507
Query: 2835 EIRGCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
E+ P+ + W R+G+ + + Y N +++ L ++ +E + G Y C A + G
Sbjct: 508 EVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIG 567
Query: 2893 NVDMNAAITVVQPSDLDGKPAV 2914
+ +VQ +D P++
Sbjct: 568 QESLE--FILVQ-ADTPSSPSI 586
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/371 (22%), Positives = 135/371 (36%), Gaps = 57/371 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVP-GVVWMK-NGHEVEEEAGRMTSQFNG-FDCCL 3109
VDI+P Q +I GE+ C V G + W NG ++ R++ +N L
Sbjct: 103 VDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTL 162
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
TI + NIDD G Y C T G S EA +K + + PQ
Sbjct: 163 TIYNANIDDAGIYKCVVTGEDGSES--------------EATVNVKIFQKLMFKNAPTPQ 208
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D + C V+ S PP + W G +V+ K+ ++ + L+I
Sbjct: 209 EFREGED--------AVIVCDVVSSLPPTIIWKHKGRDVIL-KKDVRFIVLSNNYLQIRG 259
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLYK--LHEGDELR 3286
D G Y R + G + K I+ V P + + + G +
Sbjct: 260 IKKTDEGTYRCEGRILAR------GEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVT 313
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ E +P ++W +DG ++ + D +L + V D Y C A N+
Sbjct: 314 LVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENK 373
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
G + ++V ++P+I ++ + E E V + CE
Sbjct: 374 AGEQDATIHLKVF-----AKPKI---------------TYVENQTAMELEE--QVTLTCE 411
Query: 3407 VVGDPKPDVYW 3417
GDP P + W
Sbjct: 412 ASGDPIPSITW 422
Score = 58.4 bits (135), Expect = 4e-07
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 14/193 (7%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLI 2649
+K +F T + EG + C V+SS PT+ W G V+L +++ +V
Sbjct: 197 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRF---IVLSNN 253
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHL 2706
L++ +D Y C G I + +PPT + T +L
Sbjct: 254 YLQIRGIKKTDEGTYRC-----EGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANL 308
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
++ + L C G P P ++W KD +QI + + + +D +L I D Y
Sbjct: 309 GQS-VTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 367
Query: 2767 CKAENSVWTDQIT 2779
C AEN T
Sbjct: 368 CIAENKAGEQDAT 380
Score = 53.2 bits (122), Expect = 2e-05
Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 21/191 (10%)
Query: 2598 TFLTDRTAVE-GSRVKLTCSVISSSDPTVTWY---RN----GVLLDNKLKYRKKLVDGLI 2649
T++ ++TA+E +V LTC P++TW RN LD + R +
Sbjct: 392 TYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSL 451
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAE 2708
TL+ + +D+ EY CT N G S S L+V Y P+ +
Sbjct: 452 TLKSIQY--TDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---------VYTWEG 500
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQ-AFYLADGVCRLAIDNPTPEDSGTYTC 2767
N++ + C + P I+WF+D + +PS Y L + + D G Y C
Sbjct: 501 NQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNC 560
Query: 2768 KAENSVWTDQI 2778
A N + + +
Sbjct: 561 TAVNRIGQESL 571
Score = 43.2 bits (97), Expect = 0.017
Identities = 71/338 (21%), Positives = 126/338 (37%), Gaps = 50/338 (14%)
Query: 2615 CSVISSS-DPTVTWYR-NGVLLDNKLKYRKKLV---DGLITLEVLNAVPSDSAEYSCTVE 2669
C V + D ++W+ NG L + R +V D TL + NA D+ Y C V
Sbjct: 122 CQVAGDAKDKDISWFSPNGEKLTPN-QQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVT 180
Query: 2670 NENGAIS-TSANLKVYPS--FEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
E+G+ S + N+K++ F+ +P P F + V+ C + P I
Sbjct: 181 GEDGSESEATVNVKIFQKLMFKNAPTPQEFREG---------EDAVIVCDVVSSLPPTII 231
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W + + + L++ L I D GTY C+ + +NF
Sbjct: 232 WKHKGRDVILKKDVRFIVLSNNY--LQIRGIKKTDEGTYRCEGRILARGE-----INF-- 282
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEW 2845
++ QV +V T ARQ++ + + G +T L + G P + W
Sbjct: 283 KDIQV---IVNVPPTIQARQNIVNATANLGQSVT-----------LVCDAEGFPEPTMSW 328
Query: 2846 LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
++G + + + + L + V + + Y C A + G D + V
Sbjct: 329 TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVF-- 386
Query: 2906 SDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP + E + + E + ++ G+P P
Sbjct: 387 ----AKPKITY--VENQTAMELEEQVTLTCEASGDPIP 418
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 87.4 bits (207), Expect = 8e-16
Identities = 85/328 (25%), Positives = 126/328 (38%), Gaps = 27/328 (8%)
Query: 3039 SSIGVGLAGDRPEFVDILP--GQLKILAGETAN---LTCSVKG-KPVPGVVWMKNGHEVE 3092
S GV +A + ++I P GQ+ GE C ++ V W ++E
Sbjct: 2778 SQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLE 2837
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWE--- 3149
+ +G L +KDI D+G Y C+ N +G+ S+YA L V R V++
Sbjct: 2838 NSEKYEITYEDGV-AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYC 2896
Query: 3150 --ADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEE 3207
K+KR + PP+FT+ L ++ VR + P P V+WYK G++
Sbjct: 2897 RRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQK 2956
Query: 3208 VVYDKRRNKY---QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
+ KY D+ + L I DD Y V ARN G SC L V
Sbjct: 2957 IKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TL 3011
Query: 3265 VAPEFCCGLEPLYK-------LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMT 3317
P L P++K EG + V P + W +DG L +
Sbjct: 3012 HPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 3071
Query: 3318 LDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ L + D G Y TA+N
Sbjct: 3072 HEGLDYYALHIRDTLPEDTGYYRVTATN 3099
Score = 84.6 bits (200), Expect = 6e-15
Identities = 107/443 (24%), Positives = 174/443 (39%), Gaps = 42/443 (9%)
Query: 2941 PK-PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE 2999
PK P PE P V+D + VSL+W + + V Y +E + R +
Sbjct: 1549 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKVVRHNK 1608
Query: 3000 LGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQ 3059
IT + L EY FR+ +N G E+S S + D+P PG+
Sbjct: 1609 TQITT-TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPS----QPGE 1663
Query: 3060 LKILAGETANLTCSVK------GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
L+IL+ ++T + GK + G W++ + + A + +++ D TI
Sbjct: 1664 LEILSISKDSVTLQWEKPECDGGKEILGY-WVEY-RQSGDSAWKKSNKERIKDKQFTIGG 1721
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
+ E + A N G + RT KL S E G
Sbjct: 1722 LLEATEYEFRVFAENETGLSRPR--------RTAMSIKTKLT---SGEAPG-----IRKE 1765
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
++D + +L+CQ++G P P + WY+ G+E++ ++ D + HTL + +
Sbjct: 1766 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 1825
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG--LEPLYKLHEGDELRISAVV 3291
D GVY A N G V L++ P+F G L+ Y G LR+ +
Sbjct: 1826 DEGVYTCIATNEVGEVETSSKLLLQ------ATPQFHPGYPLKEKYYGAVGSTLRLHVMY 1879
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASNEVGRA 3350
P +TW+ G +L + I + + L + V + AG Y SN G
Sbjct: 1880 IGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTV 1938
Query: 3351 STSGKVEVIGTDQTSEPRIPPVV 3373
VE+ D+ +P P V+
Sbjct: 1939 DAILDVEI--QDKPDKPTGPIVI 1959
Score = 79.8 bits (188), Expect = 2e-13
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 5/198 (2%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL---DN 2636
I + R R P F+ L ++TA G V+ ++ +P VTWY++G + DN
Sbjct: 2903 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 2962
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPP 2694
KY + GL L + + D AEY+ N+ G S A L V +P S + P
Sbjct: 2963 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 3022
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
F R + + + E R+ G P P + W KD + + + + L I
Sbjct: 3023 MFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHI 3082
Query: 2755 DNPTPEDSGTYTCKAENS 2772
+ PED+G Y A N+
Sbjct: 3083 RDTLPEDTGYYRVTATNT 3100
Score = 77.0 bits (181), Expect = 1e-12
Identities = 57/204 (27%), Positives = 89/204 (43%), Gaps = 11/204 (5%)
Query: 2943 PKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGI 3002
P A P + P P V D VSLAW + + + V Y +E + W +
Sbjct: 1256 PIAPPGK-PQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQH---EWTKCNT 1311
Query: 3003 TP--LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFV--DILPG 3058
TP + + +L QG EY FRV N G GE ++ ++ V + P++ +
Sbjct: 1312 TPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQE 1371
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + G LT +KGKP P W K G ++ + A TS+ + L IK+ + D
Sbjct: 1372 GIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH---TELVIKEADRGD 1428
Query: 3119 EGRYSCEATNTHGKASTYARLAVV 3142
G Y N GK + Y ++ V+
Sbjct: 1429 SGTYDLVLENKCGKKAVYIKVRVI 1452
Score = 77.0 bits (181), Expect = 1e-12
Identities = 97/429 (22%), Positives = 181/429 (42%), Gaps = 39/429 (9%)
Query: 2951 PGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARW--VELGITPLNS 3007
P P V++ N ++W + + Y VE A+ GA W V I+ + +
Sbjct: 1953 PTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK--CEAKEGAEWQLVSSAIS-VTT 2009
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGET 3067
NL + Y+FRV+ +N +G + + SS + + ++P PG+ I A
Sbjct: 2010 CRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG----APGKPTITAVTK 2065
Query: 3068 ANLTCSVKGKPVPGVVWMKNGH--EVEEEAGRMTSQFNGF--DCCLTIKDI--NIDDEGR 3121
+ + K G ++N + + E++ + S + ++K++ ++ E R
Sbjct: 2066 DSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFR 2125
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
CE N G++ + +++ ++D ++ P F LR+ V+
Sbjct: 2126 VKCE--NLGGESEW----SEISEPITPKSDVPIQA-----------PHFKEELRNLNVRY 2168
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYE 3239
L C+V G P P V WY+ G+E++ D + + Q+ + +H L IA DD VY+
Sbjct: 2169 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 2228
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
V A N G+VS L V+ + ++ P+ G+ ++ L G+ + I P +
Sbjct: 2229 VRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHAL-RGEVVSIKIPFSGKPDPVI 2286
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW + + + + + R + V +DAG Y A N G + +++V
Sbjct: 2287 TWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV- 2345
Query: 3360 GTDQTSEPR 3368
D PR
Sbjct: 2346 -ADVPDPPR 2353
Score = 71.7 bits (168), Expect = 4e-11
Identities = 56/202 (27%), Positives = 84/202 (41%), Gaps = 7/202 (3%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPL- 3005
P PG P V D + VSL W + V+ Y +E + G RW++ T +
Sbjct: 165 PVDAPGRPGVTDVQRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 224
Query: 3006 -NSFDAFNLKQGEEYHFRVTPRNRYG---WGESSQTSSSIGVGLAGDRPEFVDILPGQL- 3060
N F L +G+ Y FRV +N G G S + A + E L G L
Sbjct: 225 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 284
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
I AG L +V GKP P ++W K E+ + +++ Q+ G IK + D G
Sbjct: 285 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSLQYTGKRATAVIKFCDRSDSG 343
Query: 3121 RYSCEATNTHGKASTYARLAVV 3142
+Y+ N G + + V+
Sbjct: 344 KYTLTVKNASGTKAVSVMVKVL 365
Score = 71.7 bits (168), Expect = 4e-11
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 7/187 (3%)
Query: 2951 PGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS-FD 3009
P P VVD + +SLAW K ++ Y +E + R V T N+ F
Sbjct: 572 PSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR-VHTNATIRNTEFT 630
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRP--EFVDILPGQLKILAGET 3067
+LK G++Y FRV N G E S++ + I + P E D L + I AG +
Sbjct: 631 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 690
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L SV G+P P + W K G ++ A T++ L + +N D G+Y+ EA
Sbjct: 691 LRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGKYTIEAE 747
Query: 3128 NTHGKAS 3134
N GK S
Sbjct: 748 NQSGKKS 754
Score = 67.3 bits (157), Expect = 9e-10
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 3202 YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI 3261
Y+DG ++Y K K D + ++ +D E+ + +C + K
Sbjct: 2846 YEDGVAILYVKDITKLDDGTYRC-KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIK 2904
Query: 3262 RAYVA-------PEFCCGLEPLYK--LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
R PEF PLY + G+ +R + +P VTWY+ G +++P
Sbjct: 2905 RRTDTMRLLERPPEFTL---PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 2961
Query: 3313 R-AIMTLDRD-GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T + D G +L + +VTT D YT A N+ G S K+ V T P
Sbjct: 2962 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----TLHP--- 3013
Query: 3371 PVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P + PMF R ++E +EG +V E V G P P + W +D
Sbjct: 3014 -----PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKD 3058
Score = 66.9 bits (156), Expect = 1e-09
Identities = 51/184 (27%), Positives = 85/184 (46%), Gaps = 4/184 (2%)
Query: 2950 IPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFD 3009
+P + VVD + V+LAW K + + Y +E+ G E + V L T L
Sbjct: 864 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-T 922
Query: 3010 AFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQ-LKILAGET 3067
+L +GE+Y FR+ +N G E +T +++ V P + +P + + + AG
Sbjct: 923 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 982
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
L + G+P P W G ++ E+ R+T + + LTI++ I D G Y+ E
Sbjct: 983 VELVIPIAGRPPPAASWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELK 1041
Query: 3128 NTHG 3131
N G
Sbjct: 1042 NVTG 1045
Score = 66.1 bits (154), Expect = 2e-09
Identities = 77/309 (24%), Positives = 129/309 (41%), Gaps = 47/309 (15%)
Query: 2607 EGSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
EG VK C + + T VTWY L+N KY DG+ L V + D Y
Sbjct: 2808 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 2867
Query: 2666 CTVENENGAISTSANL------KVYPSFEASPI---------------PPTFTRSI-RDT 2703
C V N+ G S+ A L +VY + + PP FT + T
Sbjct: 2868 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 2927
Query: 2704 FHLAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLAD-GVCRLAIDNPTPED 2761
++ EN + I P P +TW+K ++I P D + + +D G+ +L I++ T +D
Sbjct: 2928 AYVGEN-VRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 2986
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
YT A N G +S + VT + + RP F +L +
Sbjct: 2987 DAEYTVVARNKY------------GEDSCKAKLTVTLHPP----PTDSTLRPMFKRLLAN 3030
Query: 2822 YQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTET 2878
+ G ++ ++ + G P ++W ++G+ ++ + N + + +GL Y L + D
Sbjct: 3031 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS-LGPNIEI-IHEGLDYYALHIRDTLPE 3088
Query: 2879 ESGLYTCRA 2887
++G Y A
Sbjct: 3089 DTGYYRVTA 3097
Score = 65.3 bits (152), Expect = 4e-09
Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 6/189 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGV-LLDNKLKYR-KKLVDGLITL 2651
P F L + S L C V P V WYR G ++ + LKYR ++ G L
Sbjct: 2155 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 2214
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ + D+ Y N+ G++S +A+L+V + +P T H E+
Sbjct: 2215 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGM--GAVHALRGEV 2271
Query: 2712 V-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
V ++ G+P P ITW K I ++G YQ + + +D+G Y A+
Sbjct: 2272 VSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAK 2331
Query: 2771 NSVWTDQIT 2779
N DQ T
Sbjct: 2332 NRFGIDQKT 2340
Score = 60.9 bits (141), Expect = 8e-08
Identities = 76/311 (24%), Positives = 121/311 (38%), Gaps = 20/311 (6%)
Query: 2654 LNAVPSDSAEYSC--TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
LN V S +A SC + ++ G + A +KV S E P+ ++ + +
Sbjct: 2761 LNMVVS-AARISCGGAIRSQKGV--SVAKVKV-ASIEIGPVSGQIMHAVGEE----GGHV 2812
Query: 2712 VLECRIRG-QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
C+I ++TW+ +Q+ + +Y+ Y DGV L + + T D GTY CK
Sbjct: 2813 KYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYRCKVV 2871
Query: 2771 NSVWTDQITHFVNFTG-RE--SQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
N D + G RE + K R L R P F L + G
Sbjct: 2872 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 2931
Query: 2828 GTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVE--QGLYTLALSDVTETESGLYT 2884
+ V I P V W + G+ + + + E +GLY L ++ VT + YT
Sbjct: 2932 ENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 2991
Query: 2885 CRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
A + +G A +TV + P D + R + G+ + R G P P
Sbjct: 2992 VVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPP 3051
Query: 2944 KAVPERIPGEP 2954
E+ G+P
Sbjct: 3052 TLKWEK-DGQP 3061
Score = 60.1 bits (139), Expect = 1e-07
Identities = 43/157 (27%), Positives = 69/157 (43%), Gaps = 8/157 (5%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
R+ +S K L+ S P + D T G +L+C ++ P + WYR G L
Sbjct: 1745 RTAMSIKTKLT--SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 1802
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
KY+ TL V+ D Y+C NE G + TS+ L + + + P P
Sbjct: 1803 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP-- 1860
Query: 2697 TRSIRDTFHLA-ENELVLECRIRGQPLPKITWFKDDK 2732
+++ ++ A + L L G+P+P +TWF K
Sbjct: 1861 ---LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK 1894
Score = 47.2 bits (107), Expect = 0.001
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 3/112 (2%)
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
E+ ENE G + S P + ++D L C+I G+PL
Sbjct: 1729 EFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 1788
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADG-VCRLAIDNPTPEDSGTYTCKAENSV 2773
P I W++ K++ +Y+ +DG L + ED G YTC A N V
Sbjct: 1789 PDIKWYRFGKELIQSRKYK--MSSDGRTHTLTVMTEEQEDEGVYTCIATNEV 1838
Score = 47.2 bits (107), Expect = 0.001
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 4/116 (3%)
Query: 2660 DSAEYSCTVENEN-GAISTSANLK--VYPSFEASPIPPTFTRSIRDTFHLAENELVLECR 2716
+ EY V+ EN G S + + + P + P F +R+ ++ L C+
Sbjct: 2118 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 2177
Query: 2717 IRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ G P P + W++ K+I +DG +Y+ G +L I + T +D+ Y +A N
Sbjct: 2178 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATN 2233
Score = 46.0 bits (104), Expect = 0.002
Identities = 58/240 (24%), Positives = 102/240 (42%), Gaps = 27/240 (11%)
Query: 3013 LKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTC 3072
L +G ++FRV P N YG GE +TS ++ L + P ++P +L+++ + +T
Sbjct: 828 LVEGTMHYFRVLPENIYGIGEPCETSDAV---LVSEVP----LVPAKLEVVDVTKSTVTL 880
Query: 3073 SVKGKPVPGVVWMKNGHEVEE-EAG--RMTSQFNGFDCCL--TIKDINIDDEGRYSCEAT 3127
+ + KP+ G+ +E +AG R L T+ +N ++ + A
Sbjct: 881 AWE-KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQ 939
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N G + + VT + D ++ ++ PQ T+ V A PV L
Sbjct: 940 NEKGVSEPRETVTAVTVQ-----DLRVL----PTIDLSTMPQKTIH-----VPAGRPVEL 985
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
+ G PPP SW+ G ++ +R + L I T + D G Y + +N +G
Sbjct: 986 VIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 1045
Score = 43.2 bits (97), Expect = 0.017
Identities = 56/205 (27%), Positives = 86/205 (41%), Gaps = 15/205 (7%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---D 2702
D T+ L+ D+ E+ +N G IS + + PP R D
Sbjct: 225 DNFFTVTALSE--GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD 282
Query: 2703 TFHL-AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
+ A ++LVL+ + G+P PKI W K DK++ + Y + I D
Sbjct: 283 LVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSD 341
Query: 2762 SGTYTCKAENSVWTDQITHFV---NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
SG YT +N+ T ++ V + G +++ + VT EK +A SL + G
Sbjct: 342 SGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLA-WSLP--QEDGGAE 398
Query: 2819 LTDYQVARGGTIGLQ-VEIRG-CPT 2841
+T Y V R T L V + G CPT
Sbjct: 399 ITHYIVERRETSRLNWVIVEGECPT 423
Score = 42.7 bits (96), Expect = 0.022
Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLY-TL 2870
PHF L + V L ++ G P V+W R+G+ + R+ +G Y L
Sbjct: 2155 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 2214
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
++ VT+ ++ +Y RA + G+V A++ V P+ + P + G L GE
Sbjct: 2215 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH-LPKTLEGMGAVHAL--RGEV 2271
Query: 2931 INISFRTQGEPKP 2943
++I G+P P
Sbjct: 2272 VSIKIPFSGKPDP 2284
Score = 39.9 bits (89), Expect = 0.16
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
E L+ + G LR+ V P +TW + G+ L + RAI+ + L
Sbjct: 674 ELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSL-LI 730
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
+ V DAG YT A N+ G+ S + V+V T
Sbjct: 731 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDT 764
Score = 39.9 bits (89), Expect = 0.16
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 2949 RIPGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITP- 3004
RIPG P + D + ++L W + + V Y VE + A+ RWV + P
Sbjct: 1157 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD---RWVRVNKVPV 1213
Query: 3005 -LNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
+ + + L +G EY RVT N G G+ S+ S I
Sbjct: 1214 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 1251
Score = 39.5 bits (88), Expect = 0.21
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
++A +RL V G PPP ++W K G ++ R E + L + N D G Y
Sbjct: 685 IRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDAGKY 742
Query: 3239 EVTARNNSGAVS 3250
+ A N SG S
Sbjct: 743 TIEAENQSGKKS 754
Score = 39.5 bits (88), Expect = 0.21
Identities = 37/152 (24%), Positives = 60/152 (39%), Gaps = 8/152 (5%)
Query: 3281 EGDELRISAVVEAYP-SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
EG ++ +E Y S VTWY +L S + +T + DG L + +T D G Y
Sbjct: 2808 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGTY 2866
Query: 3340 TCTASNEVGRASTSGKVEVIGT----DQTSEPRIPPVVISPDVP--YSKEPMFIRKPRSS 3393
C N+ G S+ ++ V G D + + D + P F +
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 2926
Query: 3394 EAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
A G+ V + P+P V W + K++
Sbjct: 2927 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIK 2958
Score = 37.1 bits (82), Expect = 1.1
Identities = 37/151 (24%), Positives = 61/151 (40%), Gaps = 9/151 (5%)
Query: 3225 LEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH-- 3280
LE T+L++G Y + A+N G + V P P +H
Sbjct: 919 LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 978
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
G + + + P +W+ G +LR S R +T++ ++ +L + T RD G Y
Sbjct: 979 AGRPVELVIPIAGRPPPAASWFFAGSKLRESER--VTVETHTKVAKLTIRETTIRDTGEY 1036
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
T N G +T ++VI D+ P P
Sbjct: 1037 TLELKNVTG--TTLETIKVIILDKPGPPTGP 1065
Score = 37.1 bits (82), Expect = 1.1
Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 3/83 (3%)
Query: 2956 VVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQ 3015
V D + V+L W + + + Y VE AE RW+ +G + NL
Sbjct: 2357 VSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAE---RWLRVGQARETRYTVINLFG 2413
Query: 3016 GEEYHFRVTPRNRYGWGESSQTS 3038
Y FRV N++G + S+ S
Sbjct: 2414 KTSYQFRVIAENKFGLSKPSEPS 2436
Score = 36.7 bits (81), Expect = 1.5
Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ ++L SV P +TW + G+ L ++ L+ ++ +N D+ +Y+
Sbjct: 688 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY--DAGKYTIE 745
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSI-RDT 2703
EN++G S + +KVY + P P + + RD+
Sbjct: 746 AENQSGKKSATVLVKVYDT--PGPCPSVKVKEVSRDS 780
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ +G +R++ ++ P W ++G + S+RA++ + EL + D+G
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATS-ETHTELVIKEADRGDSGT 1431
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSE 3366
Y N+ G+ + KV VIG+ + E
Sbjct: 1432 YDLVLENKCGKKAVYIKVRVIGSPNSPE 1459
Score = 35.5 bits (78), Expect = 3.4
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+RLT + G P P W K+G+++ KR E L I + D G Y++ N
Sbjct: 1381 IRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 1438
Query: 3245 NSG 3247
G
Sbjct: 1439 KCG 1441
Score = 34.7 bits (76), Expect = 5.9
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
K E +G + P+ DVP + P F + R+ R + C+V G PKP
Sbjct: 2127 KCENLGGESEWSEISEPITPKSDVPI-QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 2185
Query: 3415 VYWLR 3419
V W R
Sbjct: 2186 VKWYR 2190
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 87.4 bits (207), Expect = 8e-16
Identities = 57/174 (32%), Positives = 87/174 (50%), Gaps = 16/174 (9%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D GS ++ C PT W +NGV L + R ++V+G++ + +N S
Sbjct: 396 LNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQS--RVEMVNGVLMIHNVNQ--S 451
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT-RSIRDTFHLAEN-ELVLECRI 2717
D+ Y C EN+ GAI SA LK+ S PTF ++ T + ++ E+V+EC+
Sbjct: 452 DAGMYQCLAENKYGAIYASAELKILAS------APTFALNQLKKTIIVTKDQEVVIECKP 505
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+G P P I+W K D+ + + R L DG R+ N + D G Y C+ EN
Sbjct: 506 QGSPKPTISWKKGDRAVRENKRIA--ILPDGSLRIL--NASKSDEGKYVCRGEN 555
Score = 82.6 bits (195), Expect = 2e-14
Identities = 90/379 (23%), Positives = 145/379 (38%), Gaps = 69/379 (18%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G+ G+ +++ P + G T + C G PVP + WMK + +A SQ
Sbjct: 293 GVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ- 351
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEV 3162
L I ++ +DD G Y C A N+ GK S +L V T
Sbjct: 352 ----AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYT------------------- 388
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF 3222
YP + +L D ++ + P+R C+ G P P W K+G + R
Sbjct: 389 ---YP-HWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG--- 441
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHE 3281
L I N D G+Y+ A N GA+ L + AP F L+ + +
Sbjct: 442 -VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI-----LASAPTFALNQLKKTIIVTK 495
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
E+ I + P ++W + +R ++R + + DG + + A+ + D G Y C
Sbjct: 496 DQEVVIECKPQGSPKPTISWKKGDRAVRENKR--IAILPDGSLRILNASKS--DEGKYVC 551
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR-KPRSSEAREGDT 3400
N G A + V KEP I P+ +E G++
Sbjct: 552 RGENVFGSAEIIASLSV-----------------------KEPTRIELTPKRTELTVGES 588
Query: 3401 VIIECEVVGDPKPDV--YW 3417
+++ C+ + D DV YW
Sbjct: 589 IVLNCKAIHDASLDVTFYW 607
Score = 82.2 bits (194), Expect = 3e-14
Identities = 74/310 (23%), Positives = 135/310 (43%), Gaps = 43/310 (13%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
TA +G+ VK+ C + + PT+TW + + +K + RK LE+ N D+
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQA----VLEIPNVQLDDAGI 366
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G S L+VY P + + DT + + L EC+ G+P P
Sbjct: 367 YECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQLDSGSPLRWECKATGKPRP 419
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W K+ + R + + +GV L I N D+G Y C AEN +
Sbjct: 420 TYRWLKNGVPLSPQSRVE---MVNGV--LMIHNVNQSDAGMYQCLAENK-------YGAI 467
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TR 2842
+ E ++ + T ++ + + V D +V ++ + +G P
Sbjct: 468 YASAELKILASAPTFALNQLKKTII---------VTKDQEVV------IECKPQGSPKPT 512
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + R+V E R A + G +L + + ++++ G Y CR + G+ ++ A+++V
Sbjct: 513 ISWKKGDRAVRENKRIA--ILPDG--SLRILNASKSDEGKYVCRGENVFGSAEIIASLSV 568
Query: 2903 VQPSDLDGKP 2912
+P+ ++ P
Sbjct: 569 KEPTRIELTP 578
Score = 75.8 bits (178), Expect = 3e-12
Identities = 90/336 (26%), Positives = 130/336 (38%), Gaps = 52/336 (15%)
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V E++ R SQ G L I + D G Y C NT VT+ V
Sbjct: 239 VAEDSRRFISQETGN---LYISKVQTSDVGSYICLVKNT------------VTNARVLSP 283
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVSWYKDGEEVV 3209
L R+ V G+Y P+ + A V++ C +G+P P ++W K +
Sbjct: 284 PTPLTL-RNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIP 342
Query: 3210 YDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R K Q LEI LDD G+YE A N+ G S L V Y P +
Sbjct: 343 SKARLRKSQA----VLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV------YTYPHW 392
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
L +L G LR P W ++GV L P R M +G L +
Sbjct: 393 VEKLNDT-QLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV---NGV--LMIH 446
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
V DAG+Y C A N+ G S +++++ + T + K+ + + K
Sbjct: 447 NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA-----------LNQLKKTIIVTK 495
Query: 3390 PRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
+ V+IEC+ G PKP + W + VR
Sbjct: 496 DQE--------VVIECKPQGSPKPTISWKKGDRAVR 523
Score = 62.1 bits (144), Expect = 3e-08
Identities = 83/343 (24%), Positives = 133/343 (38%), Gaps = 46/343 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTV-TWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
EG V L CS S + +W N R+ + L + SD Y
Sbjct: 209 EGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYI 268
Query: 2666 CTVENE--NGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
C V+N N + S L + P T A+ V +EC G P
Sbjct: 269 CLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNP 328
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+P ITW K + IPS R L L I N +D+G Y C+AE
Sbjct: 329 VPTITWMKVNGYIPSKAR-----LRKSQAVLEIPNVQLDDAGIYECRAE----------- 372
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N G+ S Q PH+ L D Q+ G + + + G P
Sbjct: 373 -NSRGKNS-------------FRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPR 418
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
WL+ G ++ +RV + G+ L + +V ++++G+Y C A + +G + +A +
Sbjct: 419 PTYRWLKNGVPLSP---QSRVEMVNGV--LMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ L P + + +K I+++ +++ I + QG PKP
Sbjct: 474 KI-----LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 511
Score = 58.4 bits (135), Expect = 4e-07
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 67/362 (18%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V+G PVP W++NG E++ E+ S +G + D G Y C ATNT
Sbjct: 121 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG--TFIISNPSEAKDSGHYQCLATNT 178
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRLT 3188
G L RE A ++ Y F+ R R V+ V L
Sbjct: 179 VGSI--------------------LSRE--ATLQFAYLGNFSGRTRSAVSVREGQGVVLM 216
Query: 3189 CQVIGSPPPK-----VSW-YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
C SPPP SW + + V + R ++ ++ L I+ D G Y
Sbjct: 217 C----SPPPHSPEIIYSWVFNEFPSFVAEDSR-RFISQETGNLYISKVQTSDVGSYICLV 271
Query: 3243 RN---NSGAVSCHCGLVV-DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
+N N+ +S L + + G+ P+ +G +++ P
Sbjct: 272 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 331
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW + + PS+ + R Q L + V DAG+Y C A N G+ S G+++V
Sbjct: 332 ITWMKVNGYI-PSKARL----RKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 386
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
Y+ P ++ K ++ G + EC+ G P+P WL
Sbjct: 387 ---------------------YT-YPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWL 424
Query: 3419 RD 3420
++
Sbjct: 425 KN 426
Score = 50.8 bits (116), Expect = 8e-05
Identities = 70/304 (23%), Positives = 116/304 (38%), Gaps = 34/304 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN-AVPSDSA 2662
T + +V L C V + P+ W RNG +D + YR L+DG T + N + DS
Sbjct: 112 TDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG--TFIISNPSEAKDSG 169
Query: 2663 EYSCTVENENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQ 2720
Y C N G+I S A L+ F+ R + E + +VL C
Sbjct: 170 HYQCLATNTVGSILSREATLQF-------AYLGNFSGRTRSAVSVREGQGVVLMCSPPPH 222
Query: 2721 PLPKITWFKDDKQIPS-DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P+I + + PS +++ L I D G+Y C +N+V
Sbjct: 223 S-PEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTV------ 275
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
T P +T + + HF +T A+G T+ ++ G
Sbjct: 276 -----TNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVT---AAKGTTVKMECFALGN 327
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + W++ + AR+ Q + L + +V ++G+Y CRA ++ G
Sbjct: 328 PVPTITWMKVNGYIPS---KARLRKSQAV--LEIPNVQLDDAGIYECRAENSRGKNSFRG 382
Query: 2899 AITV 2902
+ V
Sbjct: 383 QLQV 386
Score = 46.4 bits (105), Expect = 0.002
Identities = 57/241 (23%), Positives = 92/241 (38%), Gaps = 29/241 (12%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V L C+V G+P P W ++G E+ + R D F + P+ D G Y+ A
Sbjct: 119 VALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTF--IISNPSEAKDSGHYQCLAT 176
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY-PSVGVTWY 3302
N G++ L + ++ F + EG + + + P + +W
Sbjct: 177 NTVGSI-----LSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWV 231
Query: 3303 RD---GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ SRR I G L ++ V T D G Y C N V A
Sbjct: 232 FNEFPSFVAEDSRRFIS--QETG--NLYISKVQTSDVGSYICLVKNTVTNA--------- 278
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
+ P P + + V EP + P + A +G TV +EC +G+P P + W+
Sbjct: 279 ---RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWM 335
Query: 3419 R 3419
+
Sbjct: 336 K 336
Score = 40.7 bits (91), Expect = 0.090
Identities = 48/214 (22%), Positives = 82/214 (38%), Gaps = 19/214 (8%)
Query: 2594 PVFSTFLTDRTAV--EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
P F+ +T + + V + C S PT++W + G + K L DG +L
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW-KKGDRAVRENKRIAILPDG--SL 536
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LNA SD +Y C EN G+ A+L V P ++ ++ +
Sbjct: 537 RILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGES-------I 589
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSD-----GRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
VL C+ +T++ K P D G +++ L I N +G Y
Sbjct: 590 VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYG 649
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
C+ + + D ++ R P +V E+
Sbjct: 650 CRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEE 681
Score = 40.3 bits (90), Expect = 0.12
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 10/131 (7%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKILAGETANL 3070
N+ Q + ++ N+YG +S + + P F ++ L + + + +
Sbjct: 447 NVNQSDAGMYQCLAENKYG-----AIYASAELKILASAPTFALNQLKKTIIVTKDQEVVI 501
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTH 3130
C +G P P + W K V E R+ +G L I + + DEG+Y C N
Sbjct: 502 ECKPQGSPKPTISWKKGDRAVRENK-RIAILPDG---SLRILNASKSDEGKYVCRGENVF 557
Query: 3131 GKASTYARLAV 3141
G A A L+V
Sbjct: 558 GSAEIIASLSV 568
Score = 38.7 bits (86), Expect = 0.36
Identities = 39/161 (24%), Positives = 58/161 (36%), Gaps = 12/161 (7%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW G + I P S N + +E + N +G S+ I L
Sbjct: 514 SWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFG-------SAEIIASL 566
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVV--WMKNGHEV--EEEAGRMTS- 3100
+ P +++ P + ++ GE+ L C V W G + EEE G S
Sbjct: 567 SVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESI 626
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ L I++I + GRY C T S A L V
Sbjct: 627 RAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 667
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 87.4 bits (207), Expect = 8e-16
Identities = 57/174 (32%), Positives = 87/174 (50%), Gaps = 16/174 (9%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D GS ++ C PT W +NGV L + R ++V+G++ + +N S
Sbjct: 102 LNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQS--RVEMVNGVLMIHNVNQ--S 157
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT-RSIRDTFHLAEN-ELVLECRI 2717
D+ Y C EN+ GAI SA LK+ S PTF ++ T + ++ E+V+EC+
Sbjct: 158 DAGMYQCLAENKYGAIYASAELKILAS------APTFALNQLKKTIIVTKDQEVVIECKP 211
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+G P P I+W K D+ + + R L DG R+ N + D G Y C+ EN
Sbjct: 212 QGSPKPTISWKKGDRAVRENKRIA--ILPDGSLRIL--NASKSDEGKYVCRGEN 261
Score = 82.2 bits (194), Expect = 3e-14
Identities = 74/310 (23%), Positives = 135/310 (43%), Gaps = 43/310 (13%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
TA +G+ VK+ C + + PT+TW + + +K + RK LE+ N D+
Sbjct: 17 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQA----VLEIPNVQLDDAGI 72
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G S L+VY P + + DT + + L EC+ G+P P
Sbjct: 73 YECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQLDSGSPLRWECKATGKPRP 125
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W K+ + R + + +GV L I N D+G Y C AEN +
Sbjct: 126 TYRWLKNGVPLSPQSRVE---MVNGV--LMIHNVNQSDAGMYQCLAENK-------YGAI 173
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TR 2842
+ E ++ + T ++ + + V D +V ++ + +G P
Sbjct: 174 YASAELKILASAPTFALNQLKKTII---------VTKDQEVV------IECKPQGSPKPT 218
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + R+V E R A + G +L + + ++++ G Y CR + G+ ++ A+++V
Sbjct: 219 ISWKKGDRAVRENKRIA--ILPDG--SLRILNASKSDEGKYVCRGENVFGSAEIIASLSV 274
Query: 2903 VQPSDLDGKP 2912
+P+ ++ P
Sbjct: 275 KEPTRIELTP 284
Score = 81.0 bits (191), Expect = 7e-14
Identities = 87/357 (24%), Positives = 136/357 (38%), Gaps = 68/357 (19%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G T + C G PVP + WMK + +A SQ L I ++ +DD G Y C
Sbjct: 21 GTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ-----AVLEIPNVQLDDAGIYEC 75
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N+ GK S +L V T YP + +L D ++ + P
Sbjct: 76 RAENSRGKNSFRGQLQVYT----------------------YP-HWVEKLNDTQLDSGSP 112
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+R C+ G P P W K+G + R L I N D G+Y+ A N
Sbjct: 113 LRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAEN 168
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
GA+ L + AP F L+ + + E+ I + P ++W +
Sbjct: 169 KYGAIYASAELKI-----LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKK 223
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+R ++R + + DG + + A+ + D G Y C N G A + V
Sbjct: 224 GDRAVRENKR--IAILPDGSLRILNASKS--DEGKYVCRGENVFGSAEIIASLSV----- 274
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIR-KPRSSEAREGDTVIIECEVVGDPKPDV--YW 3417
KEP I P+ +E G+++++ C+ + D DV YW
Sbjct: 275 ------------------KEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYW 313
Score = 70.9 bits (166), Expect = 7e-11
Identities = 70/263 (26%), Positives = 105/263 (39%), Gaps = 36/263 (13%)
Query: 3164 GDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF 3222
G+Y P+ + A V++ C +G+P P ++W K + R K Q
Sbjct: 2 GEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQA--- 58
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
LEI LDD G+YE A N+ G S L V Y P + L +L G
Sbjct: 59 -VLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV------YTYPHWVEKLNDT-QLDSG 110
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
LR P W ++GV L P R M +G L + V DAG+Y C
Sbjct: 111 SPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV---NG--VLMIHNVNQSDAGMYQCL 165
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVI 3402
A N+ G S +++++ + T + K+ + + K + V+
Sbjct: 166 AENKYGAIYASAELKILASAPTFA-----------LNQLKKTIIVTKDQE--------VV 206
Query: 3403 IECEVVGDPKPDVYWLRDFLKVR 3425
IEC+ G PKP + W + VR
Sbjct: 207 IECKPQGSPKPTISWKKGDRAVR 229
Score = 61.3 bits (142), Expect = 6e-08
Identities = 59/232 (25%), Positives = 100/232 (43%), Gaps = 41/232 (17%)
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+EC G P+P ITW K + IPS R L L I N +D+G Y C+AE
Sbjct: 26 MECFALGNPVPTITWMKVNGYIPSKAR-----LRKSQAVLEIPNVQLDDAGIYECRAE-- 78
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
N G+ S Q PH+ L D Q+ G +
Sbjct: 79 ----------NSRGKNS-------------FRGQLQVYTYPHWVEKLNDTQLDSGSPLRW 115
Query: 2833 QVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P WL+ G ++ +RV + G+ L + +V ++++G+Y C A + +
Sbjct: 116 ECKATGKPRPTYRWLKNGVPLSP---QSRVEMVNGV--LMIHNVNQSDAGMYQCLAENKY 170
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G + +A + + L P + + +K I+++ +++ I + QG PKP
Sbjct: 171 GAIYASAELKI-----LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 217
Score = 51.2 bits (117), Expect = 6e-05
Identities = 58/221 (26%), Positives = 88/221 (39%), Gaps = 33/221 (14%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P +V+ L ++ +G C GKP P W+KNG + ++ NG L
Sbjct: 96 PHWVEKL-NDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQS--RVEMVNGV---L 149
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I ++N D G Y C A N +G + Y A A+LK SA P
Sbjct: 150 MIHNVNQSDAGMYQCLAENKYG--AIY-------------ASAELKILASA-------PT 187
Query: 3170 FTMRLRDRRVQAT--YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
F + + + T V + C+ GSP P +SW K G+ V + +R + +L I
Sbjct: 188 FALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW-KKGDRAVRENKRIAILPD--GSLRI 244
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPE 3268
+ D G Y N G+ L V + R + P+
Sbjct: 245 LNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPK 285
Score = 40.7 bits (91), Expect = 0.090
Identities = 48/214 (22%), Positives = 82/214 (38%), Gaps = 19/214 (8%)
Query: 2594 PVFSTFLTDRTAV--EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
P F+ +T + + V + C S PT++W + G + K L DG +L
Sbjct: 186 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW-KKGDRAVRENKRIAILPDG--SL 242
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LNA SD +Y C EN G+ A+L V P ++ ++ +
Sbjct: 243 RILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGES-------I 295
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSD-----GRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
VL C+ +T++ K P D G +++ L I N +G Y
Sbjct: 296 VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYG 355
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
C+ + + D ++ R P +V E+
Sbjct: 356 CRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEE 387
Score = 40.3 bits (90), Expect = 0.12
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 10/131 (7%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKILAGETANL 3070
N+ Q + ++ N+YG +S + + P F ++ L + + + +
Sbjct: 153 NVNQSDAGMYQCLAENKYG-----AIYASAELKILASAPTFALNQLKKTIIVTKDQEVVI 207
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTH 3130
C +G P P + W K V E R+ +G L I + + DEG+Y C N
Sbjct: 208 ECKPQGSPKPTISWKKGDRAVRENK-RIAILPDG---SLRILNASKSDEGKYVCRGENVF 263
Query: 3131 GKASTYARLAV 3141
G A A L+V
Sbjct: 264 GSAEIIASLSV 274
Score = 38.7 bits (86), Expect = 0.36
Identities = 39/161 (24%), Positives = 58/161 (36%), Gaps = 12/161 (7%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW G + I P S N + +E + N +G S+ I L
Sbjct: 220 SWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFG-------SAEIIASL 272
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVV--WMKNGHEV--EEEAGRMTS- 3100
+ P +++ P + ++ GE+ L C V W G + EEE G S
Sbjct: 273 SVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESI 332
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ L I++I + GRY C T S A L V
Sbjct: 333 RAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 373
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 87.4 bits (207), Expect = 8e-16
Identities = 84/338 (24%), Positives = 143/338 (42%), Gaps = 50/338 (14%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRN-GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A +GS VKL C + + P + W R+ G+ +K+K RK G+ LE+ N D+
Sbjct: 131 AAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRK--FSGV--LEIPNFQQEDAGS 186
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G L Y P + + I+D E+ L ECR G+P P
Sbjct: 187 YECIAENSRGKNVARGRLTYYAK-------PHWVQLIKDVEIAVEDSLYWECRASGKPKP 239
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W K+ + + R Q + +G L I N + DSG + C AEN H +
Sbjct: 240 SYRWLKNGAALVLEERTQ---IENGA--LTISNLSVTDSGMFQCIAENK-------HGLV 287
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
++ E +V + K + + L QV G + L + R P +
Sbjct: 288 YSSAELKVVASAPDFSKNPMKK-------------LVQVQV--GSLVSLDCKPRASPRAL 332
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
++G + + + + G L +++VT+ ++G YTC A + G + + V
Sbjct: 333 SSWKKGDVSVQEHERISLLNDGG---LKIANVTKADAGTYTCMAENQFGKANGTTHLVVT 389
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEP 2941
+P+ + P+ ++ +SVGE + + + Q +P
Sbjct: 390 EPTRITLAPS--------NMDVSVGESVILPCQVQHDP 419
Score = 77.8 bits (183), Expect = 6e-13
Identities = 80/323 (24%), Positives = 134/323 (41%), Gaps = 44/323 (13%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G+ G+ +++ P L G T L C G P+P + W ++ ++ +F
Sbjct: 112 GVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLR-KF 170
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEV 3162
+G L I + +D G Y C A N+ GK RL AK
Sbjct: 171 SGV---LEIPNFQQEDAGSYECIAENSRGKNVARGRLTYY---------AK--------- 209
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF 3222
P + ++D + + C+ G P P W K+G +V ++R Q E
Sbjct: 210 -----PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERT---QIEN- 260
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHE 3281
L I+ ++ D G+++ A N G V L V AP+F ++ L ++
Sbjct: 261 GALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVAS-----APDFSKNPMKKLVQVQV 315
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G + + A P +W + V ++ R ++L DG +++A VT DAG YTC
Sbjct: 316 GSLVSLDCKPRASPRALSSWKKGDVSVQEHER--ISLLNDGGLKIA--NVTKADAGTYTC 371
Query: 3342 TASNEVGRASTSGKVEVIGTDQT 3364
A N+ G+A +G ++ T+ T
Sbjct: 372 MAENQFGKA--NGTTHLVVTEPT 392
Score = 72.1 bits (169), Expect = 3e-11
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 19/194 (9%)
Query: 2593 KPVFSTFLTD-RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
KP + + D AVE S + C P+ W +NG L L+ R ++ +G +T+
Sbjct: 209 KPHWVQLIKDVEIAVEDS-LYWECRASGKPKPSYRWLKNGAAL--VLEERTQIENGALTI 265
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS-IRDTFHLAENE 2710
L+ +DS + C EN++G + +SA LKV S P F+++ ++ +
Sbjct: 266 SNLSV--TDSGMFQCIAENKHGLVYSSAELKVVAS------APDFSKNPMKKLVQVQVGS 317
Query: 2711 LV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
LV L+C+ R P +W K D + R L DG ++A N T D+GTYTC A
Sbjct: 318 LVSLDCKPRASPRALSSWKKGDVSVQEHERIS--LLNDGGLKIA--NVTKADAGTYTCMA 373
Query: 2770 ENSVW-TDQITHFV 2782
EN + TH V
Sbjct: 374 ENQFGKANGTTHLV 387
Score = 59.7 bits (138), Expect = 2e-07
Identities = 82/330 (24%), Positives = 135/330 (40%), Gaps = 39/330 (11%)
Query: 3084 WMKNGHE--VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
W+ N + VEE++ R SQ G L I + D G Y+C T+ +
Sbjct: 49 WIFNEYPSFVEEDSRRFVSQETGH---LYISKVEPSDVGNYTCVVTS------------M 93
Query: 3142 VTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVS 3200
VT+ V + L RS V G+Y P+ ++ + A V+L C +G+P P+++
Sbjct: 94 VTNARVLGSPTPLVL-RSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQIN 152
Query: 3201 WYK-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK 3259
W + DG + K+ LEI +D G YE A N+ G V +
Sbjct: 153 WRRSDGLPFSSKIKLRKFSG----VLEIPNFQQEDAGSYECIAENSRGK-------NVAR 201
Query: 3260 GIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD 3319
G Y A L ++ D L P W ++G L R T
Sbjct: 202 GRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEER---TQI 258
Query: 3320 RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT--DQTSEPRIPPVVISPD 3377
+G + ++ +VT D+G++ C A N+ G +S +++V+ + D + P V +
Sbjct: 259 ENGALTISNLSVT--DSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVG 316
Query: 3378 VPYSKEPMFIRKPRS-SEAREGDTVIIECE 3406
S + PR+ S ++GD + E E
Sbjct: 317 SLVSLDCKPRASPRALSSWKKGDVSVQEHE 346
Score = 59.3 bits (137), Expect = 2e-07
Identities = 75/298 (25%), Positives = 124/298 (41%), Gaps = 46/298 (15%)
Query: 2651 LEVLNAVPSDSAEYSCTVEN--ENGAISTSANLKVYPSFEA-SPIPPTFTRSIRDTFHLA 2707
L + PSD Y+C V + N + S V S P +T A
Sbjct: 73 LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA 132
Query: 2708 ENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
+ V LEC G P+P+I W + D +P + + + GV L I N ED+G+Y
Sbjct: 133 KGSTVKLECFALGNPIPQINWRRSDG-LPFSSKIKLRKFS-GV--LEIPNFQQEDAGSYE 188
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVAR 2826
C AENS G+ NV T A +PH+ ++ D ++A
Sbjct: 189 CIAENS------------RGK------NVARGRLTYYA-------KPHWVQLIKDVEIAV 223
Query: 2827 GGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTC 2885
++ + G P WL+ G ++ R +E G L +S+++ T+SG++ C
Sbjct: 224 EDSLYWECRASGKPKPSYRWLKNGAALV---LEERTQIENG--ALTISNLSVTDSGMFQC 278
Query: 2886 RAWSAHGNVDMNAAITVVQPS-DLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
A + HG V +A + VV + D P +K + + VG +++ + + P+
Sbjct: 279 IAENKHGLVYSSAELKVVASAPDFSKNPM------KKLVQVQVGSLVSLDCKPRASPR 330
Score = 58.8 bits (136), Expect = 3e-07
Identities = 74/317 (23%), Positives = 119/317 (37%), Gaps = 40/317 (12%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+P +V ++ ++I ++ C GKP P W+KNG + E T NG
Sbjct: 209 KPHWVQLIK-DVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLE--ERTQIENG---A 262
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
LTI ++++ D G + C A N HG + A L VV + + K +
Sbjct: 263 LTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ---------- 312
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
VQ V L C+ SP SW K V +R + D L+IA
Sbjct: 313 ----------VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGG---LKIA 359
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
D G Y A N G + LVV + R +AP + G+ + +
Sbjct: 360 NVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPS-------NMDVSVGESVILP 412
Query: 3289 AVVEAYPSVGV--TWYRDG--VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
V+ P + + TWY +G + + +L + + + +G Y C
Sbjct: 413 CQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQ 472
Query: 3345 NEVGRASTSGKVEVIGT 3361
V S++ + V G+
Sbjct: 473 TGVDSVSSAADLIVRGS 489
Score = 42.3 bits (95), Expect = 0.030
Identities = 45/197 (22%), Positives = 78/197 (39%), Gaps = 16/197 (8%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
GS V L C +S +W + V + + L DG L++ N +D+ Y+C
Sbjct: 316 GSLVSLDCKPRASPRALSSWKKGDVSVQEHERI-SLLNDG--GLKIANVTKADAGTYTCM 372
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI-- 2725
EN+ G + + +L V + P S+ ++ ++L C+++ PL I
Sbjct: 373 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGES-------VILPCQVQHDPLLDIIF 425
Query: 2726 TWFKDD--KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
TW+ + DG + L I N + SG Y C + V D ++ +
Sbjct: 426 TWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGV--DSVSSAAD 483
Query: 2784 FTGRESQVSPNVVTAEK 2800
R S P V ++
Sbjct: 484 LIVRGSPGPPENVKVDE 500
Score = 37.9 bits (84), Expect = 0.64
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 13/95 (13%)
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L ++ V D G YTC ++ V A V+G+ P V+ S V EP
Sbjct: 73 LYISKVEPSDVGNYTCVVTSMVTNA------RVLGSPT------PLVLRSDGVMGEYEPK 120
Query: 3386 F-IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
++ P + A +G TV +EC +G+P P + W R
Sbjct: 121 IEVQFPETLPAAKGSTVKLECFALGNPIPQINWRR 155
Score = 35.9 bits (79), Expect = 2.6
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 6/109 (5%)
Query: 3039 SSIGVGLAGDRPEFV-DILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SS + + P+F + + +++ G +L C + P W K V+E
Sbjct: 289 SSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEH--E 346
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRT 3146
S N D L I ++ D G Y+C A N GKA+ L VVT+ T
Sbjct: 347 RISLLN--DGGLKIANVTKADAGTYTCMAENQFGKANGTTHL-VVTEPT 392
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 87.4 bits (207), Expect = 8e-16
Identities = 57/174 (32%), Positives = 87/174 (50%), Gaps = 16/174 (9%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D GS ++ C PT W +NGV L + R ++V+G++ + +N S
Sbjct: 322 LNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQS--RVEMVNGVLMIHNVNQ--S 377
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT-RSIRDTFHLAEN-ELVLECRI 2717
D+ Y C EN+ GAI SA LK+ S PTF ++ T + ++ E+V+EC+
Sbjct: 378 DAGMYQCLAENKYGAIYASAELKILAS------APTFALNQLKKTIIVTKDQEVVIECKP 431
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+G P P I+W K D+ + + R L DG R+ N + D G Y C+ EN
Sbjct: 432 QGSPKPTISWKKGDRAVRENKRIA--ILPDGSLRIL--NASKSDEGKYVCRGEN 481
Score = 82.6 bits (195), Expect = 2e-14
Identities = 90/379 (23%), Positives = 145/379 (38%), Gaps = 69/379 (18%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G+ G+ +++ P + G T + C G PVP + WMK + +A SQ
Sbjct: 219 GVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ- 277
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEV 3162
L I ++ +DD G Y C A N+ GK S +L V T
Sbjct: 278 ----AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYT------------------- 314
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF 3222
YP + +L D ++ + P+R C+ G P P W K+G + R
Sbjct: 315 ---YP-HWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG--- 367
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHE 3281
L I N D G+Y+ A N GA+ L + AP F L+ + +
Sbjct: 368 -VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI-----LASAPTFALNQLKKTIIVTK 421
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
E+ I + P ++W + +R ++R + + DG + + A+ + D G Y C
Sbjct: 422 DQEVVIECKPQGSPKPTISWKKGDRAVRENKR--IAILPDGSLRILNASKS--DEGKYVC 477
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR-KPRSSEAREGDT 3400
N G A + V KEP I P+ +E G++
Sbjct: 478 RGENVFGSAEIIASLSV-----------------------KEPTRIELTPKRTELTVGES 514
Query: 3401 VIIECEVVGDPKPDV--YW 3417
+++ C+ + D DV YW
Sbjct: 515 IVLNCKAIHDASLDVTFYW 533
Score = 82.2 bits (194), Expect = 3e-14
Identities = 74/310 (23%), Positives = 135/310 (43%), Gaps = 43/310 (13%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
TA +G+ VK+ C + + PT+TW + + +K + RK LE+ N D+
Sbjct: 237 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQA----VLEIPNVQLDDAGI 292
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G S L+VY P + + DT + + L EC+ G+P P
Sbjct: 293 YECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQLDSGSPLRWECKATGKPRP 345
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W K+ + R + + +GV L I N D+G Y C AEN +
Sbjct: 346 TYRWLKNGVPLSPQSRVE---MVNGV--LMIHNVNQSDAGMYQCLAENK-------YGAI 393
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TR 2842
+ E ++ + T ++ + + V D +V ++ + +G P
Sbjct: 394 YASAELKILASAPTFALNQLKKTII---------VTKDQEVV------IECKPQGSPKPT 438
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + R+V E R A + G +L + + ++++ G Y CR + G+ ++ A+++V
Sbjct: 439 ISWKKGDRAVRENKRIA--ILPDG--SLRILNASKSDEGKYVCRGENVFGSAEIIASLSV 494
Query: 2903 VQPSDLDGKP 2912
+P+ ++ P
Sbjct: 495 KEPTRIELTP 504
Score = 75.8 bits (178), Expect = 3e-12
Identities = 90/336 (26%), Positives = 130/336 (38%), Gaps = 52/336 (15%)
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V E++ R SQ G L I + D G Y C NT VT+ V
Sbjct: 165 VAEDSRRFISQETGN---LYISKVQTSDVGSYICLVKNT------------VTNARVLSP 209
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVSWYKDGEEVV 3209
L R+ V G+Y P+ + A V++ C +G+P P ++W K +
Sbjct: 210 PTPLTL-RNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIP 268
Query: 3210 YDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R K Q LEI LDD G+YE A N+ G S L V Y P +
Sbjct: 269 SKARLRKSQA----VLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV------YTYPHW 318
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
L +L G LR P W ++GV L P R M +G L +
Sbjct: 319 VEKLNDT-QLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV---NGV--LMIH 372
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
V DAG+Y C A N+ G S +++++ + T + K+ + + K
Sbjct: 373 NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA-----------LNQLKKTIIVTK 421
Query: 3390 PRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
+ V+IEC+ G PKP + W + VR
Sbjct: 422 DQE--------VVIECKPQGSPKPTISWKKGDRAVR 449
Score = 62.1 bits (144), Expect = 3e-08
Identities = 83/343 (24%), Positives = 133/343 (38%), Gaps = 46/343 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTV-TWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
EG V L CS S + +W N R+ + L + SD Y
Sbjct: 135 EGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYI 194
Query: 2666 CTVENE--NGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
C V+N N + S L + P T A+ V +EC G P
Sbjct: 195 CLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNP 254
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+P ITW K + IPS R L L I N +D+G Y C+AE
Sbjct: 255 VPTITWMKVNGYIPSKAR-----LRKSQAVLEIPNVQLDDAGIYECRAE----------- 298
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N G+ S Q PH+ L D Q+ G + + + G P
Sbjct: 299 -NSRGKNS-------------FRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPR 344
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
WL+ G ++ +RV + G+ L + +V ++++G+Y C A + +G + +A +
Sbjct: 345 PTYRWLKNGVPLSP---QSRVEMVNGV--LMIHNVNQSDAGMYQCLAENKYGAIYASAEL 399
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ L P + + +K I+++ +++ I + QG PKP
Sbjct: 400 KI-----LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 437
Score = 58.4 bits (135), Expect = 4e-07
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 67/362 (18%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V+G PVP W++NG E++ E+ S +G + D G Y C ATNT
Sbjct: 47 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG--TFIISNPSEAKDSGHYQCLATNT 104
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRLT 3188
G L RE A ++ Y F+ R R V+ V L
Sbjct: 105 VGSI--------------------LSRE--ATLQFAYLGNFSGRTRSAVSVREGQGVVLM 142
Query: 3189 CQVIGSPPPK-----VSW-YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
C SPPP SW + + V + R ++ ++ L I+ D G Y
Sbjct: 143 C----SPPPHSPEIIYSWVFNEFPSFVAEDSR-RFISQETGNLYISKVQTSDVGSYICLV 197
Query: 3243 RN---NSGAVSCHCGLVV-DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
+N N+ +S L + + G+ P+ +G +++ P
Sbjct: 198 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 257
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW + + PS+ + R Q L + V DAG+Y C A N G+ S G+++V
Sbjct: 258 ITWMKVNGYI-PSKARL----RKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 312
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
Y+ P ++ K ++ G + EC+ G P+P WL
Sbjct: 313 ---------------------YT-YPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWL 350
Query: 3419 RD 3420
++
Sbjct: 351 KN 352
Score = 50.8 bits (116), Expect = 8e-05
Identities = 70/304 (23%), Positives = 116/304 (38%), Gaps = 34/304 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN-AVPSDSA 2662
T + +V L C V + P+ W RNG +D + YR L+DG T + N + DS
Sbjct: 38 TDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG--TFIISNPSEAKDSG 95
Query: 2663 EYSCTVENENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQ 2720
Y C N G+I S A L+ F+ R + E + +VL C
Sbjct: 96 HYQCLATNTVGSILSREATLQF-------AYLGNFSGRTRSAVSVREGQGVVLMCSPPPH 148
Query: 2721 PLPKITWFKDDKQIPS-DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P+I + + PS +++ L I D G+Y C +N+V
Sbjct: 149 S-PEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTV------ 201
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
T P +T + + HF +T A+G T+ ++ G
Sbjct: 202 -----TNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVT---AAKGTTVKMECFALGN 253
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + W++ + AR+ Q + L + +V ++G+Y CRA ++ G
Sbjct: 254 PVPTITWMKVNGYIPS---KARLRKSQAV--LEIPNVQLDDAGIYECRAENSRGKNSFRG 308
Query: 2899 AITV 2902
+ V
Sbjct: 309 QLQV 312
Score = 46.4 bits (105), Expect = 0.002
Identities = 57/241 (23%), Positives = 92/241 (38%), Gaps = 29/241 (12%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V L C+V G+P P W ++G E+ + R D F + P+ D G Y+ A
Sbjct: 45 VALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTF--IISNPSEAKDSGHYQCLAT 102
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY-PSVGVTWY 3302
N G++ L + ++ F + EG + + + P + +W
Sbjct: 103 NTVGSI-----LSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWV 157
Query: 3303 RD---GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ SRR I G L ++ V T D G Y C N V A
Sbjct: 158 FNEFPSFVAEDSRRFIS--QETG--NLYISKVQTSDVGSYICLVKNTVTNA--------- 204
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
+ P P + + V EP + P + A +G TV +EC +G+P P + W+
Sbjct: 205 ---RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWM 261
Query: 3419 R 3419
+
Sbjct: 262 K 262
Score = 40.7 bits (91), Expect = 0.090
Identities = 48/214 (22%), Positives = 82/214 (38%), Gaps = 19/214 (8%)
Query: 2594 PVFSTFLTDRTAV--EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
P F+ +T + + V + C S PT++W + G + K L DG +L
Sbjct: 406 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW-KKGDRAVRENKRIAILPDG--SL 462
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LNA SD +Y C EN G+ A+L V P ++ ++ +
Sbjct: 463 RILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGES-------I 515
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSD-----GRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
VL C+ +T++ K P D G +++ L I N +G Y
Sbjct: 516 VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYG 575
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
C+ + + D ++ R P +V E+
Sbjct: 576 CRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEE 607
Score = 40.3 bits (90), Expect = 0.12
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 10/131 (7%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKILAGETANL 3070
N+ Q + ++ N+YG +S + + P F ++ L + + + +
Sbjct: 373 NVNQSDAGMYQCLAENKYG-----AIYASAELKILASAPTFALNQLKKTIIVTKDQEVVI 427
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTH 3130
C +G P P + W K V E R+ +G L I + + DEG+Y C N
Sbjct: 428 ECKPQGSPKPTISWKKGDRAVRENK-RIAILPDG---SLRILNASKSDEGKYVCRGENVF 483
Query: 3131 GKASTYARLAV 3141
G A A L+V
Sbjct: 484 GSAEIIASLSV 494
Score = 38.7 bits (86), Expect = 0.36
Identities = 39/161 (24%), Positives = 58/161 (36%), Gaps = 12/161 (7%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW G + I P S N + +E + N +G S+ I L
Sbjct: 440 SWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFG-------SAEIIASL 492
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVV--WMKNGHEV--EEEAGRMTS- 3100
+ P +++ P + ++ GE+ L C V W G + EEE G S
Sbjct: 493 SVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESI 552
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ L I++I + GRY C T S A L V
Sbjct: 553 RAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 593
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 87.4 bits (207), Expect = 8e-16
Identities = 57/174 (32%), Positives = 87/174 (50%), Gaps = 16/174 (9%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D GS ++ C PT W +NGV L + R ++V+G++ + +N S
Sbjct: 396 LNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQS--RVEMVNGVLMIHNVNQ--S 451
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT-RSIRDTFHLAEN-ELVLECRI 2717
D+ Y C EN+ GAI SA LK+ S PTF ++ T + ++ E+V+EC+
Sbjct: 452 DAGMYQCLAENKYGAIYASAELKILAS------APTFALNQLKKTIIVTKDQEVVIECKP 505
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+G P P I+W K D+ + + R L DG R+ N + D G Y C+ EN
Sbjct: 506 QGSPKPTISWKKGDRAVRENKRIA--ILPDGSLRIL--NASKSDEGKYVCRGEN 555
Score = 82.6 bits (195), Expect = 2e-14
Identities = 90/379 (23%), Positives = 145/379 (38%), Gaps = 69/379 (18%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G+ G+ +++ P + G T + C G PVP + WMK + +A SQ
Sbjct: 293 GVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ- 351
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEV 3162
L I ++ +DD G Y C A N+ GK S +L V T
Sbjct: 352 ----AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYT------------------- 388
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF 3222
YP + +L D ++ + P+R C+ G P P W K+G + R
Sbjct: 389 ---YP-HWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG--- 441
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG-LEPLYKLHE 3281
L I N D G+Y+ A N GA+ L + AP F L+ + +
Sbjct: 442 -VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI-----LASAPTFALNQLKKTIIVTK 495
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
E+ I + P ++W + +R ++R + + DG + + A+ + D G Y C
Sbjct: 496 DQEVVIECKPQGSPKPTISWKKGDRAVRENKR--IAILPDGSLRILNASKS--DEGKYVC 551
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR-KPRSSEAREGDT 3400
N G A + V KEP I P+ +E G++
Sbjct: 552 RGENVFGSAEIIASLSV-----------------------KEPTRIELTPKRTELTVGES 588
Query: 3401 VIIECEVVGDPKPDV--YW 3417
+++ C+ + D DV YW
Sbjct: 589 IVLNCKAIHDASLDVTFYW 607
Score = 82.2 bits (194), Expect = 3e-14
Identities = 74/310 (23%), Positives = 135/310 (43%), Gaps = 43/310 (13%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
TA +G+ VK+ C + + PT+TW + + +K + RK LE+ N D+
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQA----VLEIPNVQLDDAGI 366
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G S L+VY P + + DT + + L EC+ G+P P
Sbjct: 367 YECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQLDSGSPLRWECKATGKPRP 419
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W K+ + R + + +GV L I N D+G Y C AEN +
Sbjct: 420 TYRWLKNGVPLSPQSRVE---MVNGV--LMIHNVNQSDAGMYQCLAENK-------YGAI 467
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TR 2842
+ E ++ + T ++ + + V D +V ++ + +G P
Sbjct: 468 YASAELKILASAPTFALNQLKKTII---------VTKDQEVV------IECKPQGSPKPT 512
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + R+V E R A + G +L + + ++++ G Y CR + G+ ++ A+++V
Sbjct: 513 ISWKKGDRAVRENKRIA--ILPDG--SLRILNASKSDEGKYVCRGENVFGSAEIIASLSV 568
Query: 2903 VQPSDLDGKP 2912
+P+ ++ P
Sbjct: 569 KEPTRIELTP 578
Score = 75.8 bits (178), Expect = 3e-12
Identities = 90/336 (26%), Positives = 130/336 (38%), Gaps = 52/336 (15%)
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V E++ R SQ G L I + D G Y C NT VT+ V
Sbjct: 239 VAEDSRRFISQETGN---LYISKVQTSDVGSYICLVKNT------------VTNARVLSP 283
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVSWYKDGEEVV 3209
L R+ V G+Y P+ + A V++ C +G+P P ++W K +
Sbjct: 284 PTPLTL-RNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIP 342
Query: 3210 YDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R K Q LEI LDD G+YE A N+ G S L V Y P +
Sbjct: 343 SKARLRKSQA----VLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV------YTYPHW 392
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
L +L G LR P W ++GV L P R M +G L +
Sbjct: 393 VEKLNDT-QLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV---NGV--LMIH 446
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
V DAG+Y C A N+ G S +++++ + T + K+ + + K
Sbjct: 447 NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA-----------LNQLKKTIIVTK 495
Query: 3390 PRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
+ V+IEC+ G PKP + W + VR
Sbjct: 496 DQE--------VVIECKPQGSPKPTISWKKGDRAVR 523
Score = 62.1 bits (144), Expect = 3e-08
Identities = 83/343 (24%), Positives = 133/343 (38%), Gaps = 46/343 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTV-TWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
EG V L CS S + +W N R+ + L + SD Y
Sbjct: 209 EGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYI 268
Query: 2666 CTVENE--NGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQP 2721
C V+N N + S L + P T A+ V +EC G P
Sbjct: 269 CLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNP 328
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+P ITW K + IPS R L L I N +D+G Y C+AE
Sbjct: 329 VPTITWMKVNGYIPSKAR-----LRKSQAVLEIPNVQLDDAGIYECRAE----------- 372
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
N G+ S Q PH+ L D Q+ G + + + G P
Sbjct: 373 -NSRGKNS-------------FRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPR 418
Query: 2842 RV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
WL+ G ++ +RV + G+ L + +V ++++G+Y C A + +G + +A +
Sbjct: 419 PTYRWLKNGVPLSP---QSRVEMVNGV--LMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
+ L P + + +K I+++ +++ I + QG PKP
Sbjct: 474 KI-----LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 511
Score = 58.4 bits (135), Expect = 4e-07
Identities = 86/362 (23%), Positives = 138/362 (38%), Gaps = 67/362 (18%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V+G PVP W++NG E++ E+ S +G + D G Y C ATNT
Sbjct: 121 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG--TFIISNPSEAKDSGHYQCLATNT 178
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR-RVQATYPVRLT 3188
G L RE A ++ Y F+ R R V+ V L
Sbjct: 179 VGSI--------------------LSRE--ATLQFAYLGNFSGRTRSAVSVREGQGVVLM 216
Query: 3189 CQVIGSPPPK-----VSW-YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
C SPPP SW + + V + R ++ ++ L I+ D G Y
Sbjct: 217 C----SPPPHSPEIIYSWVFNEFPSFVAEDSR-RFISQETGNLYISKVQTSDVGSYICLV 271
Query: 3243 RN---NSGAVSCHCGLVV-DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
+N N+ +S L + + G+ P+ +G +++ P
Sbjct: 272 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 331
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+TW + + PS+ + R Q L + V DAG+Y C A N G+ S G+++V
Sbjct: 332 ITWMKVNGYI-PSKARL----RKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 386
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
Y+ P ++ K ++ G + EC+ G P+P WL
Sbjct: 387 ---------------------YT-YPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWL 424
Query: 3419 RD 3420
++
Sbjct: 425 KN 426
Score = 50.8 bits (116), Expect = 8e-05
Identities = 70/304 (23%), Positives = 116/304 (38%), Gaps = 34/304 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLN-AVPSDSA 2662
T + +V L C V + P+ W RNG +D + YR L+DG T + N + DS
Sbjct: 112 TDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG--TFIISNPSEAKDSG 169
Query: 2663 EYSCTVENENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQ 2720
Y C N G+I S A L+ F+ R + E + +VL C
Sbjct: 170 HYQCLATNTVGSILSREATLQF-------AYLGNFSGRTRSAVSVREGQGVVLMCSPPPH 222
Query: 2721 PLPKITWFKDDKQIPS-DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P+I + + PS +++ L I D G+Y C +N+V
Sbjct: 223 S-PEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTV------ 275
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
T P +T + + HF +T A+G T+ ++ G
Sbjct: 276 -----TNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVT---AAKGTTVKMECFALGN 327
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P + W++ + AR+ Q + L + +V ++G+Y CRA ++ G
Sbjct: 328 PVPTITWMKVNGYIPS---KARLRKSQAV--LEIPNVQLDDAGIYECRAENSRGKNSFRG 382
Query: 2899 AITV 2902
+ V
Sbjct: 383 QLQV 386
Score = 46.4 bits (105), Expect = 0.002
Identities = 57/241 (23%), Positives = 92/241 (38%), Gaps = 29/241 (12%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
V L C+V G+P P W ++G E+ + R D F + P+ D G Y+ A
Sbjct: 119 VALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTF--IISNPSEAKDSGHYQCLAT 176
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY-PSVGVTWY 3302
N G++ L + ++ F + EG + + + P + +W
Sbjct: 177 NTVGSI-----LSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWV 231
Query: 3303 RD---GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ SRR I G L ++ V T D G Y C N V A
Sbjct: 232 FNEFPSFVAEDSRRFIS--QETG--NLYISKVQTSDVGSYICLVKNTVTNA--------- 278
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMF-IRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
+ P P + + V EP + P + A +G TV +EC +G+P P + W+
Sbjct: 279 ---RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWM 335
Query: 3419 R 3419
+
Sbjct: 336 K 336
Score = 40.7 bits (91), Expect = 0.090
Identities = 48/214 (22%), Positives = 82/214 (38%), Gaps = 19/214 (8%)
Query: 2594 PVFSTFLTDRTAV--EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
P F+ +T + + V + C S PT++W + G + K L DG +L
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW-KKGDRAVRENKRIAILPDG--SL 536
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+LNA SD +Y C EN G+ A+L V P ++ ++ +
Sbjct: 537 RILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGES-------I 589
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSD-----GRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
VL C+ +T++ K P D G +++ L I N +G Y
Sbjct: 590 VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYG 649
Query: 2767 CKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
C+ + + D ++ R P +V E+
Sbjct: 650 CRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEE 681
Score = 40.3 bits (90), Expect = 0.12
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 10/131 (7%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEF-VDILPGQLKILAGETANL 3070
N+ Q + ++ N+YG +S + + P F ++ L + + + +
Sbjct: 447 NVNQSDAGMYQCLAENKYG-----AIYASAELKILASAPTFALNQLKKTIIVTKDQEVVI 501
Query: 3071 TCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTH 3130
C +G P P + W K V E R+ +G L I + + DEG+Y C N
Sbjct: 502 ECKPQGSPKPTISWKKGDRAVRENK-RIAILPDG---SLRILNASKSDEGKYVCRGENVF 557
Query: 3131 GKASTYARLAV 3141
G A A L+V
Sbjct: 558 GSAEIIASLSV 568
Score = 38.7 bits (86), Expect = 0.36
Identities = 39/161 (24%), Positives = 58/161 (36%), Gaps = 12/161 (7%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW G + I P S N + +E + N +G S+ I L
Sbjct: 514 SWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFG-------SAEIIASL 566
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVV--WMKNGHEV--EEEAGRMTS- 3100
+ P +++ P + ++ GE+ L C V W G + EEE G S
Sbjct: 567 SVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESI 626
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ L I++I + GRY C T S A L V
Sbjct: 627 RAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 667
>AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform
protein.
Length = 1294
Score = 87.0 bits (206), Expect = 1e-15
Identities = 62/225 (27%), Positives = 99/225 (44%), Gaps = 5/225 (2%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
ES++ S G+ P+ L + + G+TA C +K V W G ++E
Sbjct: 1074 ESTELSKECAKESTGEAPKIFLHLQ-DVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIE 1132
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
E SQ NG LTI ++ + D+G YSC N G+ +T A L+V E+
Sbjct: 1133 ESERLKQSQ-NGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV---EGAPESIL 1188
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
+ E+ E+E P ++ V + + TC++ +P + W+K G E+
Sbjct: 1189 HERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESD 1248
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ + + +LEI T + D G Y A N G+VSC L V
Sbjct: 1249 KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293
Score = 86.2 bits (204), Expect = 2e-15
Identities = 64/197 (32%), Positives = 90/197 (45%), Gaps = 12/197 (6%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKK 2643
TL N+ P L T G + C+VIS P ++WY+ LL K K
Sbjct: 786 TLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLSTGFKC-KF 843
Query: 2644 LVDGL-ITLEVLNAVPSDSAEYSCTVENENGAISTSANLK------VYPSFEASPIPPTF 2696
L DG TL ++ A P D+A Y+C +N+ G +TSA+L V P E PP
Sbjct: 844 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAI 903
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
++DT +CR+ G L K++W+ DK+I R+ + +L I
Sbjct: 904 ITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAE 961
Query: 2757 PTPEDSGTYTCKAENSV 2773
PED GTYT A N+V
Sbjct: 962 AYPEDEGTYTFVASNAV 978
Score = 77.0 bits (181), Expect = 1e-12
Identities = 64/215 (29%), Positives = 98/215 (45%), Gaps = 16/215 (7%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDE 3220
V PPQ L+ VQ+ P R + G P PK+SWYK+ E+++ + K+ D
Sbjct: 789 VNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDG 847
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP---LY 3277
Q +TL + +D VY A+N+ G + L V+ + V+P+ + P +
Sbjct: 848 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE--VPEVVSPDQEMPVYPPAIIT 905
Query: 3278 KLH-----EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L EG R V + V+WY +++PSR MT D +L +A
Sbjct: 906 PLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAY 963
Query: 3333 TRDAGVYTCTASNEVGRASTSG--KVEVIGTDQTS 3365
D G YT ASN VG+ S++ +EV D+ S
Sbjct: 964 PEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQS 998
Score = 74.5 bits (175), Expect = 6e-12
Identities = 57/184 (30%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 3201 WYKDGEEVVYD-KRRNKYQDEQ-FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
WYKDG E+ + + R+KY E+ H + I+ T D G Y A N +V+ +
Sbjct: 735 WYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLY------ 788
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ A P+ L+P+ + G R AV+ P ++WY++ L +
Sbjct: 789 --VNAPEPPQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL- 844
Query: 3319 DRDGQ-IELALAAVTTRDAGVYTCTASNEVGRASTSGKV-----EVIGTDQTSEPRIPPV 3372
DGQ L L DA VYTC A N+ G A+TS + EV+ DQ P PP
Sbjct: 845 -HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPA 902
Query: 3373 VISP 3376
+I+P
Sbjct: 903 IITP 906
Score = 69.7 bits (163), Expect = 2e-10
Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 12/197 (6%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ +G+ A + G+P P + W K ++ + +G + L + + +D
Sbjct: 806 VQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 864
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+CEA N +G A+T A L+V E + ++ V YPP L+D
Sbjct: 865 YTCEAKNDYGVATTSASLSV-------EVPEVVSPDQEMPV---YPPAIITPLQDTVTSE 914
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P R C+V G+ KVSWY +++ + Q E + LEIA +D G Y
Sbjct: 915 GQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 973
Query: 3242 ARNNSGAVSCHCGLVVD 3258
A N G VS L ++
Sbjct: 974 ASNAVGQVSSTANLSLE 990
Score = 52.0 bits (119), Expect = 4e-05
Identities = 52/218 (23%), Positives = 78/218 (35%), Gaps = 16/218 (7%)
Query: 2568 HRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW 2627
H + A S K ++ P L D T G + C + S VTW
Sbjct: 1065 HTASLSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTW 1124
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
G ++ + ++ + L + N D YSC V N+ G +TSA L V +
Sbjct: 1125 THEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAP 1184
Query: 2688 EA-------------SPIPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQ 2733
E+ P R I + +A L C I+ P + WFK ++
Sbjct: 1185 ESILHERIEQEIEMEMKAAPVIKRKI-EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 1243
Query: 2734 IPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
I + + + + L I D G YTCKA N
Sbjct: 1244 IYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKASN 1280
Score = 51.2 bits (117), Expect = 6e-05
Identities = 51/221 (23%), Positives = 92/221 (41%), Gaps = 19/221 (8%)
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
+L +E + E G+ P F + L+D V+ + C + V+W +G ++ +
Sbjct: 1077 ELSKECAKESTGEAPKIF-LHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE 1135
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYV------- 3265
R + Q+ L I L D G+Y N+ G + L V+ + +
Sbjct: 1136 RLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQE 1195
Query: 3266 -------APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMT 3317
AP +EPL ++ G + + +++ P+V W++ G + S + +I +
Sbjct: 1196 IEMEMKAAPVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS 1254
Query: 3318 LDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+E+ V D G YTC ASNE G S + + V
Sbjct: 1255 SKYISSLEILRTQVV--DCGEYTCKASNEYGSVSCTATLTV 1293
Score = 48.8 bits (111), Expect = 3e-04
Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 7/140 (5%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE-LALAAVTTRDAGVYT 3340
GD + V++ + VTW +G ++ S R + ++G I+ L + V D G+Y+
Sbjct: 1105 GDTAQFLCVLKDDSFIDVTWTHEGAKIEESER--LKQSQNGNIQFLTICNVQLVDQGLYS 1162
Query: 3341 CTASNEVGRASTSGKVEVIGTDQT-SEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C N+ G +TS + V G ++ RI + ++ P+ RK E G
Sbjct: 1163 CIVHNDCGERTTSAVLSVEGAPESILHERIEQEI---EMEMKAAPVIKRKIEPLEVALGH 1219
Query: 3400 TVIIECEVVGDPKPDVYWLR 3419
CE+ P W +
Sbjct: 1220 LAKFTCEIQSAPNVRFQWFK 1239
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P T L D EG + C V S +D V+WY + +R + LE+
Sbjct: 901 PAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 959
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A P D Y+ N G +S++ANL +
Sbjct: 960 AEAYPEDEGTYTFVASNAVGQVSSTANLSL 989
Score = 46.0 bits (104), Expect = 0.002
Identities = 41/191 (21%), Positives = 74/191 (38%), Gaps = 12/191 (6%)
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
C ++ +TW + +I R + + + L I N D G Y+C N
Sbjct: 1112 CVLKDDSFIDVTWTHEGAKIEESERLKQSQNGN-IQFLTICNVQLVDQGLYSCIVHNDCG 1170
Query: 2775 TDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQV 2834
+ ++ G +P + E+ + P + +VA G
Sbjct: 1171 ERTTSAVLSVEG-----APESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTC 1225
Query: 2835 EIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY--TLALSDVTETESGLYTCRAWSAH 2891
EI+ P R +W + GR E+Y + + + Y +L + + G YTC+A + +
Sbjct: 1226 EIQSAPNVRFQWFKAGR---EIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 1282
Query: 2892 GNVDMNAAITV 2902
G+V A +TV
Sbjct: 1283 GSVSCTATLTV 1293
Score = 42.7 bits (96), Expect = 0.022
Identities = 24/90 (26%), Positives = 39/90 (43%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV + G K TC + S+ + W++ G + K + + +LE+
Sbjct: 1204 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 1263
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
L D EY+C NE G++S +A L V
Sbjct: 1264 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293
Score = 40.7 bits (91), Expect = 0.090
Identities = 46/185 (24%), Positives = 76/185 (41%), Gaps = 20/185 (10%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLN 2655
T L D +EG++ L C V +V WY N + D+++ + +V G V+N
Sbjct: 5 TPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVIN 61
Query: 2656 AV-PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
SD Y V G + T+ NL V E I R +RD +V E
Sbjct: 62 RTHASDEGPYKLIV----GRVETNCNLSV----EKIKI----IRGLRDLTCTETQNVVFE 109
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
+ + + W DK+I +Y+ + +L + N +D G YT A ++
Sbjct: 110 VELSHSGI-DVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEGKYTFYAGENIT 167
Query: 2775 TDQIT 2779
+ ++T
Sbjct: 168 SGKLT 172
Score = 40.3 bits (90), Expect = 0.12
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 21/187 (11%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L + T E T + + V W +NGV+L++ KY + + +L + N
Sbjct: 269 LKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIV 328
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D + Y + G + SA L V E I + +D L + E +
Sbjct: 329 DESVYGFRL----GRLGASARLHV----ETVKI----IKKPKDVTALENATVAFEVSVSH 376
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT-------CKAENS 2772
+P + WF + +I +++ V +L + N +P D+G YT CKA+
Sbjct: 377 DTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLF 434
Query: 2773 VWTDQIT 2779
V T IT
Sbjct: 435 VETLHIT 441
Score = 39.1 bits (87), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+F ++D +V C+V P V W KD +E+ R +++ H L I
Sbjct: 615 EFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIP 673
Query: 3229 PTNLDDGGVYEVTARNN 3245
T + D G Y V A N
Sbjct: 674 STRMSDAGKYTVVAGGN 690
Score = 35.5 bits (78), Expect = 3.4
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERS 3159
+G D KD I +Y EA HGK L ++ D + + A + +
Sbjct: 115 SGIDVLWNFKDKEIKPSSKYKIEA---HGKIYKLTVLNMMKDDEGKYTFYAGENITSGKL 171
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
G + L D+ V + C+V +P K W +DG+ + D
Sbjct: 172 TVAGG----AISKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESD 226
Query: 3220 EQFHTLEIAPTNLDDGGVY 3238
L IA T LDD G Y
Sbjct: 227 GHKRRLIIAATKLDDIGEY 245
>AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform
protein.
Length = 5604
Score = 86.2 bits (204), Expect = 2e-15
Identities = 64/197 (32%), Positives = 90/197 (45%), Gaps = 12/197 (6%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKK 2643
TL N+ P L T G + C+VIS P ++WY+ LL K K
Sbjct: 3230 TLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLSTGFKC-KF 3287
Query: 2644 LVDGL-ITLEVLNAVPSDSAEYSCTVENENGAISTSANLK------VYPSFEASPIPPTF 2696
L DG TL ++ A P D+A Y+C +N+ G +TSA+L V P E PP
Sbjct: 3288 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAI 3347
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
++DT +CR+ G L K++W+ DK+I R+ + +L I
Sbjct: 3348 ITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAE 3405
Query: 2757 PTPEDSGTYTCKAENSV 2773
PED GTYT A N+V
Sbjct: 3406 AYPEDEGTYTFVASNAV 3422
Score = 82.2 bits (194), Expect = 3e-14
Identities = 88/358 (24%), Positives = 138/358 (38%), Gaps = 35/358 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITL 2651
KPVF +EG + V+ P W+ +G + N ++ + DG +L
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ A PSDS E++ +N G S S L V + P F +++ ++L
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTV--EAVEHQVKPMFVEKLKNVNIKEGSQL 1573
Query: 2712 VLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
++ R G P P I W K+ D +P G L ID+ +DS YT A
Sbjct: 1574 EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1633
Query: 2771 NSVWTDQITHFVNFTGRESQVSPN---VV---TAEKTRIARQSLE--------------- 2809
N D VN ++ P ++ T IA LE
Sbjct: 1634 NKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGD 1693
Query: 2810 ------SRRPHFGNVLTDYQVARGGTIGLQVEIR--GCPTR-VEWLREGRSVTEVYRNAR 2860
++P F LT ++ R G + + G PT VEWL +G+ + E R
Sbjct: 1694 LYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLR 1752
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G +L +SG+ TCRA + +G +A + V L + + GR
Sbjct: 1753 MINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGR 1810
Score = 79.8 bits (188), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 79.4 bits (187), Expect = 2e-13
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 4/208 (1%)
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD- 3211
+L+ +++E Y P F ++ + R +V+G P P+ W+ DG+++V D
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 3212 KRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC 3271
+ +++ +L I P D G + V A+N +G S L V+ + V P F
Sbjct: 1502 THKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE-AVEHQVKPMFVE 1560
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD-RDGQIELALAA 3330
L+ + + EG +L + P+ + W ++ + P + + ++ G+ L + +
Sbjct: 1561 KLKNV-NIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1619
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEV 3358
++D+ YT TA N+ GR +T KV V
Sbjct: 1620 TVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 77.8 bits (183), Expect = 6e-13
Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 14/217 (6%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDE 3220
V PPQ L+ VQ+ P R + G P PK+SWYK+ E+++ + K+ D
Sbjct: 3233 VNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDG 3291
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP---LY 3277
Q +TL + +D VY A+N+ G + L V+ + V+P+ + P +
Sbjct: 3292 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE--VPEVVSPDQEMPVYPPAIIT 3349
Query: 3278 KLH-----EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L EG R V + V+WY +++PSR MT D +L +A
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAY 3407
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
D G YT ASN VG+ S++ + + + RI
Sbjct: 3408 PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444
Score = 77.4 bits (182), Expect = 9e-13
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 74.5 bits (175), Expect = 6e-12
Identities = 92/369 (24%), Positives = 141/369 (38%), Gaps = 18/369 (4%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++S T G G P F+ P K++ G + C V G P P V W K+G +
Sbjct: 1066 DTSLTEEQAGPGEPA-APYFIT-KPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1123
Query: 3093 EEAGRMTSQFNGF--DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
R +N +C L I DD G Y+ N HG+ S A L + EA
Sbjct: 1124 T-GYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-------LEEA 1175
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +L + E+ Y Q T +++ +V T P + + + + +
Sbjct: 1176 DYELLMKSQQEML--YQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEV-TARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R +D++FH + + + T + VD V F
Sbjct: 1234 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1293
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
++ Y++ EG + + YP + WY+DG R++ R M +DG+ L +
Sbjct: 1294 DLRIKN-YRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI-R 3388
V D G+YT ASN G A SGK+ V P P + S P + R
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412
Query: 3389 KP-RSSEAR 3396
P R S AR
Sbjct: 1413 SPIRMSPAR 1421
Score = 74.5 bits (175), Expect = 6e-12
Identities = 57/184 (30%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 3201 WYKDGEEVVYD-KRRNKYQDEQ-FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
WYKDG E+ + + R+KY E+ H + I+ T D G Y A N +V+ +
Sbjct: 3179 WYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLY------ 3232
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ A P+ L+P+ + G R AV+ P ++WY++ L +
Sbjct: 3233 --VNAPEPPQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL- 3288
Query: 3319 DRDGQ-IELALAAVTTRDAGVYTCTASNEVGRASTSGKV-----EVIGTDQTSEPRIPPV 3372
DGQ L L DA VYTC A N+ G A+TS + EV+ DQ P PP
Sbjct: 3289 -HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPA 3346
Query: 3373 VISP 3376
+I+P
Sbjct: 3347 IITP 3350
Score = 74.1 bits (174), Expect = 8e-12
Identities = 58/231 (25%), Positives = 97/231 (41%), Gaps = 24/231 (10%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PPT +++ + + LEC I G P P +TW+++D QI S +Q + G+ RL
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 1000
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFV------NFTGRESQVSPNVVTAEKTRIARQ 2806
I EDSG +TC A N T + ++ F + V+ T EK + +
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 2807 SL---------------ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
+ E P+F ++ GG++ ++ G P V W + G
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 2851 SVTEVYRNARVFVEQ-GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+T YR + +Q G L +S ++G YT + HG +A++
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 69.7 bits (163), Expect = 2e-10
Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 12/197 (6%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ +G+ A + G+P P + W K ++ + +G + L + + +D
Sbjct: 3250 VQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3308
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+CEA N +G A+T A L+V E + ++ V YPP L+D
Sbjct: 3309 YTCEAKNDYGVATTSASLSV-------EVPEVVSPDQEMPV---YPPAIITPLQDTVTSE 3358
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P R C+V G+ KVSWY +++ + Q E + LEIA +D G Y
Sbjct: 3359 GQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3417
Query: 3242 ARNNSGAVSCHCGLVVD 3258
A N G VS L ++
Sbjct: 3418 ASNAVGQVSSTANLSLE 3434
Score = 68.9 bits (161), Expect = 3e-10
Identities = 60/221 (27%), Positives = 87/221 (39%), Gaps = 28/221 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ GE+ L C + G P P V W + +++E + +G L I++ +D GR
Sbjct: 954 VIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI-ARLMIREAFAEDSGR 1012
Query: 3122 YSCEATNTHGKASTYARLAV------------------------VTDRTVWEADAKLKRE 3157
++C A N G ST LAV V R V D L E
Sbjct: 1013 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1072
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
++ E P T + + V+ V CQV G+P P V W K G + R
Sbjct: 1073 QAGPGEPAAPYFITKPVVQKLVEGG-SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVS 1131
Query: 3218 QDEQFH--TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++Q L I+ T DD G Y + RN G S L+
Sbjct: 1132 YNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1172
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/175 (29%), Positives = 80/175 (45%), Gaps = 26/175 (14%)
Query: 3267 PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIEL 3326
P GL+ + + EG+ + + + YPS VTWYR+ ++ S +T + G L
Sbjct: 943 PTLVSGLKNVTVI-EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 1000
Query: 3327 ALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ-------------TSEPRIPPV- 3372
+ D+G +TC+A NE G STS + V +++ T E R
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 3373 -VISPDVPYSKE---------PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ D ++E P FI KP + EG +V+ C+V G+PKP VYW
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115
Score = 66.1 bits (154), Expect = 2e-09
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G PT V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 65.3 bits (152), Expect = 4e-09
Identities = 107/483 (22%), Positives = 196/483 (40%), Gaps = 51/483 (10%)
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
L + V G ++ L+ I G P+ V W RE + E + ++ + G+ L + +
Sbjct: 949 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSIDFQITFQSGIARLMIREAFA 1007
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR---PEKDILIS---VGEDI 2931
+SG +TC A + G V + + V + + + + + EK + S V D
Sbjct: 1008 EDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDT 1067
Query: 2932 NISFRTQGEPKPKA--------VPERIPGEPCVVD---GGNNWVSLAWPKSD-PQTTAPV 2979
+++ G +P A V + + G V GGN + W KS P TT
Sbjct: 1068 SLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-- 1125
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
YKV + G + + +T F GE + + RN++ GE+S ++S
Sbjct: 1126 YRYKVS---YNKQTGECKLVISMT-------FADDAGE---YTIVVRNKH--GETSASAS 1170
Query: 3040 SIGVGLAGDRPEFVDILPGQLKIL--AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
+ + ++ ++ Q ++L TA + G+ PG V+ + E E+E
Sbjct: 1171 LL------EEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQAL 1224
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ + D + ++D+ + K Y R+ T + E D + K
Sbjct: 1225 IRKKM-AKD--TVVVRTYVEDQEFHISSFEERLIKEIEY-RIIKTTLEELLEEDGEEKMA 1280
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNK 3216
F +R+++ R+ V C++ G P PK++WYKDG+ + + +R +
Sbjct: 1281 VDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1340
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
+ + +L I +D G+Y A N G C L V+ AP + LEP+
Sbjct: 1341 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPA-APLGAPTYIPTLEPV 1399
Query: 3277 YKL 3279
++
Sbjct: 1400 SRI 1402
Score = 64.5 bits (150), Expect = 6e-09
Identities = 31/95 (32%), Positives = 47/95 (49%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + L + T +EG V L C + PTVTWYR +++ + ++ G+ L +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
A DS ++C+ NE G +STS L V S E
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 1037
Score = 62.1 bits (144), Expect = 3e-08
Identities = 32/84 (38%), Positives = 42/84 (50%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E+ + F I++ L + C++ G PLPKI W+KD K+I RYQ +L D
Sbjct: 1285 ESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1344
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAEN 2771
G L I PED G YT A N
Sbjct: 1345 GRASLRIPVVLPEDEGIYTAFASN 1368
Score = 62.1 bits (144), Expect = 3e-08
Identities = 64/239 (26%), Positives = 105/239 (43%), Gaps = 33/239 (13%)
Query: 2688 EASPIPPTFTRSIRDTFHLAEN-ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E +PP F I D F + EN + V +C + G P P++ W+K+ I D
Sbjct: 5374 EVFEMPPRFIMPICD-FKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEE 5432
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
G L I N DS TY C+A N V F+ T +S++ V A+K+++
Sbjct: 5433 KGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL--TMGDSEIF--AVIAKKSKVTLS 5488
Query: 2807 SLESR---RPHFGNVLTDYQVARG---------------GTIG-LQVEIRGCP-TRVEWL 2846
SL + ++ + ++QV G GT Q +RG P V W
Sbjct: 5489 SLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWY 5548
Query: 2847 REGRSVTEVYRNARVFVEQ---GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
++G+ V + R VE+ G + L ++ + +++ G Y C A + G + AA+T+
Sbjct: 5549 KDGKLV----QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 61.3 bits (142), Expect = 6e-08
Identities = 75/354 (21%), Positives = 141/354 (39%), Gaps = 23/354 (6%)
Query: 2571 KAFSEARSVISEKRTLSRNSTR--KPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTV 2625
K F E+R V+ +L+ +P F+T + VEG V C V + P V
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113
Query: 2626 TWYRNGVLLDNKLKYRKKL--VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
W ++GV L +Y+ G L + D+ EY+ V N++G S SA+L
Sbjct: 1114 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1173
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA 2742
+E +S ++ + + V E ++ G+ P + + +K+ + QA
Sbjct: 1174 EADYE------LLMKSQQEMLYQTQVTAFVQEPKV-GETAPGFVYSEYEKEYEKE---QA 1223
Query: 2743 FYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
+ ED + E + +I + + T E + + EK
Sbjct: 1224 LIRKKMAKDTVVVRTYVEDQEFHISSFEERL-IKEIEYRIIKTTLEELLEED--GEEKMA 1280
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARV 2861
+ E+ F + +Y++ G + ++ G P ++ W ++G+ + R
Sbjct: 1281 VDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1340
Query: 2862 FVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVI 2915
F++ G +L + V + G+YT A + GN + + V+P+ G P I
Sbjct: 1341 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL-YVEPAAPLGAPTYI 1393
Score = 59.3 bits (137), Expect = 2e-07
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 18/149 (12%)
Query: 3273 LEPL-YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P+ +K EG R V P W+ DG ++ + + DG L +
Sbjct: 1461 LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPA 1520
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
T D+G +T A N GR+S + VI T + E ++ +PMF+ K +
Sbjct: 1521 TPSDSGEWTVVAQNRAGRSS----ISVILTVEAVEHQV-------------KPMFVEKLK 1563
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ +EG + ++ G+P PD+ WL++
Sbjct: 1564 NVNIKEGSQLEMKVRATGNPNPDIVWLKN 1592
Score = 59.3 bits (137), Expect = 2e-07
Identities = 27/79 (34%), Positives = 43/79 (54%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C + P VTW++NGVLL K++ + V+ L + + DS +Y C
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKC 4231
Query: 2667 TVENENGAISTSANLKVYP 2685
EN +GA+ + ++L V P
Sbjct: 4232 VAENNSGAVESVSDLTVEP 4250
Score = 59.3 bits (137), Expect = 2e-07
Identities = 60/217 (27%), Positives = 81/217 (37%), Gaps = 23/217 (10%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
KI A CSV G P P V W K +E + + L I+++ + D
Sbjct: 5390 KIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSA 5449
Query: 3121 RYSCEATNTHGKA--------------STYARLAVVTDRTVWEADAKLKRERSAE----- 3161
Y C A N G+A + A+ + VT ++ E + LK +
Sbjct: 5450 TYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLME-ELVLKSNYTDSFFEFQ 5508
Query: 3162 -VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
VEG PP+F + D C V GSP P V WYKDG+ V + +
Sbjct: 5509 VVEG--PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGT 5566
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
FH L I D G Y A N SG L +
Sbjct: 5567 GFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/277 (24%), Positives = 115/277 (41%), Gaps = 32/277 (11%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRYS 3123
G A+ V GKP P W KNG ++E + R+ + + C L I+D+ +D
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIER-SDRIYWYWPEDNVCELVIRDVTAEDSASIM 2150
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
+A N G+ S++A L V AK + E++ + +++ AT+
Sbjct: 2151 VKAINIAGETSSHAFLLV---------QAKQLITFTQELQD-------VVAKEKDTMATF 2194
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C+ P KV WYKDG EV + + D + H L I + D Y
Sbjct: 2195 E----CET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+ V L+V+ + EF L+ + ++ E + +V ++ WY
Sbjct: 2250 EDEN-VKTTAKLIVEGAV-----VEFVKELQDI-EVPESYSGELECIVSP-ENIEGKWYH 2301
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
+ V L+ + + +T R G+ L + VT D G Y+
Sbjct: 2302 NDVELKSNGKYTIT-SRRGRQNLTVKDVTKEDQGEYS 2337
Score = 58.8 bits (136), Expect = 3e-07
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 35/222 (15%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-FH 3223
+ PP+F M + D ++ C VIG P P+V WYK+ + D + +E+ H
Sbjct: 5377 EMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV-DKGIRAYVAPEFCCGLEPL------ 3276
TL+I L D Y A N G C L + D I A +A + L L
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496
Query: 3277 ----------YKLHEGDELRISAVVEAYPSVG----------------VTWYRDGVRLRP 3310
+++ EG I + + Y +G V WY+DG +L
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDG-KLVQ 5555
Query: 3311 SRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
RR + G L + ++ D G Y C A+N+ G A +
Sbjct: 5556 GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAES 5597
Score = 58.0 bits (134), Expect = 6e-07
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 57.2 bits (132), Expect = 1e-06
Identities = 90/397 (22%), Positives = 152/397 (38%), Gaps = 56/397 (14%)
Query: 3076 GKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAS 3134
G P V W+ +G +E RM ++F G+ C L D G +C ATN +G
Sbjct: 1730 GDPTMVVEWLHDGKPLEAANRLRMINEF-GY-CSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 3135 TYARLAVVTDRTVWEA----DAKLKRERSAEVEG----------------DYPPQFTMRL 3174
T A L V ++++ E + + +R E+E P +
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1847
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
RV R C+V G P PKV+WY +G +++ +R + + + H L+I D
Sbjct: 1848 EPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIHYLDIVDCKSYD 1906
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD--KGIRAYV--APEFCCGLEPLYKLHEGDELRISAV 3290
G +VTA N G + L + + R+ + APE P + +HE +L+ V
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPE----PRPEFHVHEPGKLQFE-V 1961
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV-GR 3349
+ V T ++ V+L+ + R + EL + G Y + E+ R
Sbjct: 1962 QKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSR 2021
Query: 3350 ASTSGKVEVIG-------------TDQ-----TSEPRIPPVVISPD----VPYSKEPMFI 3387
E++ T++ E +I PD P + P
Sbjct: 2022 KKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF 2081
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+ +S +G VVG P P+ W ++ +K+
Sbjct: 2082 ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2118
Score = 56.4 bits (130), Expect = 2e-06
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 5/99 (5%)
Query: 3045 LAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
+ + P+ + +P + G++ L C + G+P P V W +NG +++ QF
Sbjct: 4153 ITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQ---NQKFQFEE 4209
Query: 3105 FDCC--LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+C L IKD+N D G+Y C A N G + + L V
Sbjct: 4210 VNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 8/194 (4%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDEQFHTLE 3226
P+ R++ + V +V+G P P+ WYK+G ++ R Y ++ L
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I +D V A N +G S H L+V +A F L+ + E D +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQLITFTQELQDVV-AKEKDTMA 2192
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ P V V WY+DG+ + + M DR L++ + T DA Y+C E
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHF-LSILTIDTSDAEDYSCVLV-E 2250
Query: 3347 VGRASTSGKVEVIG 3360
T+ K+ V G
Sbjct: 2251 DENVKTTAKLIVEG 2264
Score = 54.4 bits (125), Expect = 7e-06
Identities = 54/214 (25%), Positives = 90/214 (42%), Gaps = 25/214 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDC 3107
+P FV + P K L G+TA V G+P+P W +G + V + ++ + +G
Sbjct: 1456 KPVFV-LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ- 1513
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I D G ++ A N G++S L V EA VE
Sbjct: 1514 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV-------EA-----------VEHQVK 1555
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVV---YDKRRNKYQDEQFHT 3224
P F +L++ ++ + + + G+P P + W K+ + +V Y K R + +
Sbjct: 1556 PMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE-AA 1614
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
L+I T D Y TA N +G + C + V+
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648
Score = 52.4 bits (120), Expect = 3e-05
Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F++ L + K+ T V+G PVPGV W +N +E + R+ + G C L
Sbjct: 5183 PSFIEPLTKR-KVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDE-RIKMERVGNVCSL 5240
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I +I + G Y C A N G+A ++A + ++
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 52.0 bits (119), Expect = 4e-05
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF--- 3222
PP+ + + R + + L C + G P P V+W+++G V K+ K+Q E+
Sbjct: 4157 PPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNG---VLLKQNQKFQFEEVNCS 4213
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
H L I N D G Y+ A NNSGAV L V+
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVE 4249
Score = 51.6 bits (118), Expect = 5e-05
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK-Y 2640
+K LS + +F + +T +GS V+ DP WY+NGV ++ + Y
Sbjct: 2067 DKIELSPSMEAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2125
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSI 2700
D + L + + DSA N G S+ A L V +A + TFT+ +
Sbjct: 2126 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQL-ITFTQEL 2180
Query: 2701 RDTFHLAENEL-VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+D ++ + EC +P K+ W+KD ++ +Y+ + V L+I
Sbjct: 2181 QDVVAKEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSDRKVHFLSILTIDT 2238
Query: 2760 EDSGTYTC 2767
D+ Y+C
Sbjct: 2239 SDAEDYSC 2246
Score = 51.2 bits (117), Expect = 6e-05
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T + +KP + +EG + C V P V WY NG L+ ++R +
Sbjct: 1832 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR- 1890
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
DG+ L++++ D+ E T EN G I L++
Sbjct: 1891 YDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 50.0 bits (114), Expect = 1e-04
Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Query: 2588 RNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG 2647
+++ P F LT R E + + V P V WYRN LL+ + + + V
Sbjct: 5177 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 5236
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE-ASPIPPTFT 2697
+ +LE+ N + EY C N G + AN+ + P E +PP T
Sbjct: 5237 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVT 5287
Score = 50.0 bits (114), Expect = 1e-04
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 5/103 (4%)
Query: 3273 LEPLYK--LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALA 3329
+EPL K ++E L VE P GV WYR+ L P R + ++R G + L ++
Sbjct: 5186 IEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDER--IKMERVGNVCSLEIS 5243
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPV 3372
+ + G Y C A N +G A + V+++ ++ PPV
Sbjct: 5244 NIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPV 5286
Score = 48.8 bits (111), Expect = 3e-04
Identities = 49/257 (19%), Positives = 94/257 (36%), Gaps = 7/257 (2%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F + + V C G P P V+WY + + ++ + E + L
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILT 4002
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
++ + + G N G V L V +A + P++ + +E
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKV----KAKQKHDVKAHKVPVFHDYLDEEEE 4058
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASN 3345
++ V + + ++G + + G EL V + A
Sbjct: 4059 LALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQDK 4118
Query: 3346 EVGRASTSGKVE--VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVII 3403
E + ++E + DQ ++ V D+ M P+ + REGD++I+
Sbjct: 4119 ESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIIL 4178
Query: 3404 ECEVVGDPKPDVYWLRD 3420
EC + G+P+P V W ++
Sbjct: 4179 ECLISGEPQPVVTWFQN 4195
Score = 48.4 bits (110), Expect = 5e-04
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-- 3223
+ P FT +L + V PV TC++I P P+++W+ + + RR + H
Sbjct: 3502 FKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHH 3561
Query: 3224 --TLEIAPTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKG 3260
+LEI D G Y + A N+ G A S LV+ KG
Sbjct: 3562 SSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKG 3601
Score = 48.0 bits (109), Expect = 6e-04
Identities = 40/143 (27%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT-VENENGAISTSANLKV 2683
V WY++G+ + KYR + L +L SD+ +YSC VE+EN + T+A L V
Sbjct: 2205 VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN--VKTTAKLIV 2262
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
E + + F + ++D LEC + + + + W+ +D ++ S+G+Y
Sbjct: 2263 ----EGAVV--EFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKY-TI 2314
Query: 2744 YLADGVCRLAIDNPTPEDSGTYT 2766
G L + + T ED G Y+
Sbjct: 2315 TSRRGRQNLTVKDVTKEDQGEYS 2337
Score = 48.0 bits (109), Expect = 6e-04
Identities = 37/123 (30%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 2565 DMRHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
D+ H+S A S IS T S KP F+ LT + +EG V TC +I+ P
Sbjct: 3477 DIDHKSMAAKRYASRISS--TSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPE 3534
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGL----ITLEVLNAVPSDSAEYSCTVENENGAISTSAN 2680
+TW+ N + L+ K L +LE+ DS Y N G+ ++A+
Sbjct: 3535 MTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTAS 3594
Query: 2681 LKV 2683
L V
Sbjct: 3595 LLV 3597
Score = 47.6 bits (108), Expect = 8e-04
Identities = 22/64 (34%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ ++LEC I G+P P +TWF++ + + ++Q F + +L I + +DSG Y C
Sbjct: 4174 DSIILECLISGEPQPVVTWFQNGVLLKQNQKFQ-FEEVNCSHQLYIKDVNSQDSGKYKCV 4232
Query: 2769 AENS 2772
AEN+
Sbjct: 4233 AENN 4236
Score = 47.6 bits (108), Expect = 8e-04
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 1/85 (1%)
Query: 2687 FEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
F+ PP F + I D + +C +RG P P + W+KD K + R+
Sbjct: 5507 FQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRRFTVEESG 5565
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAEN 2771
G L I + D G Y C A N
Sbjct: 5566 TGFHNLFITSLVKSDEGEYRCVATN 5590
Score = 46.8 bits (106), Expect = 0.001
Identities = 27/88 (30%), Positives = 41/88 (46%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F ++D A G+ C V S PTV WY++G L+ + ++ G L +
Sbjct: 5514 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFI 5573
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANL 2681
+ V SD EY C N++G + A L
Sbjct: 5574 TSLVKSDEGEYRCVATNKSGMAESFAAL 5601
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P T L D EG + C V S +D V+WY + +R + LE+
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A P D Y+ N G +S++ANL +
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 8/137 (5%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
+++ PS EA P F R T ++ R+ G+P P+ W+K+ +I R
Sbjct: 2069 IELSPSMEA---PKIFERIQSQTVGQG-SDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2124
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVV 2796
++ D VC L I + T EDS + KA N F+ ++ +Q +VV
Sbjct: 2125 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVV 2184
Query: 2797 TAEKTRIARQSLESRRP 2813
EK +A E+ P
Sbjct: 2185 AKEKDTMATFECETSEP 2201
Score = 44.8 bits (101), Expect = 0.006
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
Score = 44.8 bits (101), Expect = 0.006
Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 18/162 (11%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+K+ E + V P+ V WY++ + + P + + G L + V D+
Sbjct: 5389 FKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDS 5448
Query: 3337 GVYTCTASNEVGRA-----STSGKVEVIG-----TDQTSEPRIPPVVISPDVPYS----- 3381
Y C A N VG A T G E+ + T + +V+ + S
Sbjct: 5449 ATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQ 5508
Query: 3382 ---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P FI+ A G +C V G P+P VYW +D
Sbjct: 5509 VVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKD 5550
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+P+ V + P +++L GETA C V G P P V W NG ++ ++ R +++G
Sbjct: 1840 KPDIV-LYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIH-Y 1896
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I D D G A N G +L +
Sbjct: 1897 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 44.0 bits (99), Expect = 0.010
Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 16/212 (7%)
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +K VEG +F L+D V +Y L C ++ + WY + E+
Sbjct: 2251 DENVKTTAKLIVEGAVV-EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKS 2308
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+ + L + +D G Y C L + A +
Sbjct: 2309 NGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT----CKLKMKPRPIAILQ---- 2360
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL K+ EGD +++ V GV W +DG ++PS R + +D+ + L +
Sbjct: 2361 -GLSD-QKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHM-LLIED 2416
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+T DAG Y+ T +G STSG+V V D
Sbjct: 2417 MTKEDAGNYSFTIP-ALG-LSTSGRVSVYSVD 2446
Score = 43.6 bits (98), Expect = 0.013
Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P F ++ G T +++ G P W +G+ + Y + V E G +L
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
+ T ++SG +T A + G ++ +T V+ + KP + K++ I G
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFV--EKLKNVNIKEGSQ 1572
Query: 2931 INISFRTQGEPKPKAV 2946
+ + R G P P V
Sbjct: 1573 LEMKVRATGNPNPDIV 1588
Score = 43.2 bits (97), Expect = 0.017
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L+D+ EG V+L V S V W ++G + + + L + +
Sbjct: 2362 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKE 2420
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ YS T+ +STS + VY +P+ +D + + VLEC++
Sbjct: 2421 DAGNYSFTIPALG--LSTSGRVSVYSVDVITPL--------KDVNVIEGTKAVLECKVSV 2470
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ + W+ +D+QI D R QA + RL I+ D G Y
Sbjct: 2471 PDVTSVKWYLNDEQIKPDDRVQAI-VKGTKQRLVINRTHASDEGPY 2515
Score = 42.7 bits (96), Expect = 0.022
Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ + Q ++ G++ N C +G P P V W N + + + L
Sbjct: 3944 PSFLQEIESQ-EVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYS-IL 4001
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T+ ++ +EG +C N +G T + L V
Sbjct: 4002 TLSSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
Score = 42.3 bits (95), Expect = 0.030
Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 8/90 (8%)
Query: 3278 KLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAG 3337
+ EGD + + ++ P VTW+++GV L+ +++ + + +L + V ++D+G
Sbjct: 4169 RCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQK-FQFEEVNCSHQLYIKDVNSQDSG 4227
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
Y C A N SG VE + +D T EP
Sbjct: 4228 KYKCVAEN------NSGAVESV-SDLTVEP 4250
Score = 42.3 bits (95), Expect = 0.030
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLITLE 2652
P F + D E S CSVI P V WY+ + ++ + +KY G TL+
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 2653 VLNAVPSDSAEYSCTVEN 2670
+ N SDSA Y C N
Sbjct: 5440 IRNVCLSDSATYRCRAVN 5457
Score = 40.7 bits (91), Expect = 0.090
Identities = 25/91 (27%), Positives = 37/91 (40%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP L++ V V L C + G P P V+WY++ ++ L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G + +A N +G VS C L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 40.7 bits (91), Expect = 0.090
Identities = 57/251 (22%), Positives = 92/251 (36%), Gaps = 27/251 (10%)
Query: 2714 ECRIR--GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
ECR+ G P + W D K + + R + G C L DSG TC+A N
Sbjct: 1723 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATN 1781
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG---NVLTD------- 2821
TD + + +S V + + + + R R H G V TD
Sbjct: 1782 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1841
Query: 2822 --------YQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+V G T + + G P +V W G+ + + R RV + G++ L +
Sbjct: 1842 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR-FRVRYD-GIHYLDI 1899
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
D ++G A + G ++ + + Q D +V+ PE V E
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF---RSVLRRAPEPRPEFHVHEPGK 1956
Query: 2933 ISFRTQGEPKP 2943
+ F Q +P
Sbjct: 1957 LQFEVQKVDRP 1967
Score = 40.7 bits (91), Expect = 0.090
Identities = 46/185 (24%), Positives = 76/185 (41%), Gaps = 20/185 (10%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLN 2655
T L D +EG++ L C V +V WY N + D+++ + +V G V+N
Sbjct: 2449 TPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVIN 2505
Query: 2656 AV-PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
SD Y V G + T+ NL V E I R +RD +V E
Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSV----EKIKI----IRGLRDLTCTETQNVVFE 2553
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
+ + + W DK+I +Y+ + +L + N +D G YT A ++
Sbjct: 2554 VELSHSGI-DVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEGKYTFYAGENIT 2611
Query: 2775 TDQIT 2779
+ ++T
Sbjct: 2612 SGKLT 2616
Score = 40.3 bits (90), Expect = 0.12
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 21/187 (11%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L + T E T + + V W +NGV+L++ KY + + +L + N
Sbjct: 2713 LKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIV 2772
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D + Y + G + SA L V E I + +D L + E +
Sbjct: 2773 DESVYGFRL----GRLGASARLHV----ETVKI----IKKPKDVTALENATVAFEVSVSH 2820
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT-------CKAENS 2772
+P + WF + +I +++ V +L + N +P D+G YT CKA+
Sbjct: 2821 DTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLF 2878
Query: 2773 VWTDQIT 2779
V T IT
Sbjct: 2879 VETLHIT 2885
Score = 40.3 bits (90), Expect = 0.12
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 3147 VWEADA-KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDG 3205
+W +D+ E + + PP F L R+V + +V G P P V WY++
Sbjct: 5161 IWRSDSFGTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNK 5220
Query: 3206 EEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
+ D+R + +LEI+ +GG Y A N G
Sbjct: 5221 SLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIG 5262
Score = 39.9 bits (89), Expect = 0.16
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 17/169 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E +L C ++S + WY N V L + KY G L V +
Sbjct: 2273 LQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKE 2331
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIR 2718
D EYS ++ + T+ LK+ P P + + D + E ++V LE ++
Sbjct: 2332 DQGEYSFVIDGK----KTTCKLKM------KPRPIAILQGLSDQ-KVCEGDIVQLEVKVS 2380
Query: 2719 GQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
+ + + W KD +++ PSD + + L I++ T ED+G Y+
Sbjct: 2381 LESVEGV-WMKDGQEVQPSDRVH--IVIDKQSHMLLIEDMTKEDAGNYS 2426
Score = 39.9 bits (89), Expect = 0.16
Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 13/141 (9%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY-- 2868
+P F LT V G + + CPT + W R + R + E L+
Sbjct: 3503 KPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRI-IKAESDLHHH 3561
Query: 2869 --TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEK----- 2921
+L + V + +SG Y A ++ G+ + A++ V+Q D K + R E+
Sbjct: 3562 SSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ-DEKYLEFLKRAERTHENV 3620
Query: 2922 DILISVGED-INISFRTQGEP 2941
+ L+ GED I + R G P
Sbjct: 3621 EALVERGEDRIKVDLRFTGSP 3641
Score = 39.9 bits (89), Expect = 0.16
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 4/97 (4%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM---TSQFNGF 3105
+P F L + +L GE TC + P P + W N + R+ S +
Sbjct: 3503 KPSFTQKLTFKY-VLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHH 3561
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L IK + D G Y A N+ G A + A L V+
Sbjct: 3562 SSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVI 3598
Score = 39.5 bits (88), Expect = 0.21
Identities = 15/38 (39%), Positives = 23/38 (60%)
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+P+F+ KP S + EG T + +VVG P P+ +W D
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1493
Score = 39.5 bits (88), Expect = 0.21
Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 5/123 (4%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD---GVC 2750
P+FT+ + + L +V CR+ P P++TWF +++ IP+ R +D
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWTDQITH--FVNFTGRESQVSPNVVTAEKTRIARQSL 2808
L I DSG+Y A NS + + T V G++ + + AE+T ++L
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAERTHENVEAL 3623
Query: 2809 ESR 2811
R
Sbjct: 3624 VER 3626
Score = 39.1 bits (87), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+F ++D +V C+V P V W KD +E+ R +++ H L I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIP 3117
Query: 3229 PTNLDDGGVYEVTARNN 3245
T + D G Y V A N
Sbjct: 3118 STRMSDAGKYTVVAGGN 3134
Score = 39.1 bits (87), Expect = 0.28
Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 3/105 (2%)
Query: 2686 SFEASP--IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
SF P PP+F + I + C +G P P +TW+ +D IP + +
Sbjct: 3934 SFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNF-II 3992
Query: 2744 YLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE 2788
+ + L + + ++ G+ TC N T + T + ++
Sbjct: 3993 HSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQ 4037
Score = 38.7 bits (86), Expect = 0.36
Identities = 65/299 (21%), Positives = 109/299 (36%), Gaps = 40/299 (13%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDC 3107
+P FV+ L + I G + G P P +VW+KN V + ++ + +
Sbjct: 1555 KPMFVEKLKN-VNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1613
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL----KRERSAEV- 3162
L I D Y+ A N G+ +T ++ V + E + KL R+ E+
Sbjct: 1614 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1673
Query: 3163 -----------------EGD-------YPPQFTMRLRDRRVQATYPVRLTCQV--IGSPP 3196
EGD P F +L R++ P C++ IG P
Sbjct: 1674 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPT 1733
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
V W DG+ + R + + +L+ D G+ A N G L+
Sbjct: 1734 MVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Query: 3257 V--DKG-IRAYVAPEFCCGLEPLYKL----HEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
V +K + PE GL+ + +L HEG ++ + + Y + VR+
Sbjct: 1794 VKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1852
Score = 38.3 bits (85), Expect = 0.48
Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+PP+F + L + G P+P + W+++ + D R + + + VC
Sbjct: 5181 MPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN-VCS 5239
Query: 2752 LAIDNPTPEDSGTYTCKAENSV 2773
L I N + G Y C A N +
Sbjct: 5240 LEISNIQKGEGGEYMCHAVNII 5261
Score = 37.1 bits (82), Expect = 1.1
Identities = 19/90 (21%), Positives = 35/90 (38%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F + + EG C P VTWY N + + + ++ L +
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + +C + N+ G + T++ LKV
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
Score = 37.1 bits (82), Expect = 1.1
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F LT +V T+G VE+ G P V+W R +S+ E ++ + +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYR-NKSLLEPDERIKMERVGNVCSLE 5241
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+S++ + E G Y C A + G A + ++
Sbjct: 5242 ISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 36.3 bits (80), Expect = 1.9
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 3049 RPEFVDILPG--QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
+P + IL G K+ G+ L V + V GV WMK+G EV + + R+ +
Sbjct: 2352 KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEV-QPSDRVHIVIDKQS 2409
Query: 3107 CCLTIKDINIDDEGRYS----CEATNTHGKASTYA 3137
L I+D+ +D G YS +T G+ S Y+
Sbjct: 2410 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS 2444
Score = 35.9 bits (79), Expect = 2.6
Identities = 26/120 (21%), Positives = 52/120 (43%), Gaps = 6/120 (5%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F + D+++ + + G PT V+W +E + + E+G +TL
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
+ +V ++S Y CRA + G +T+ D + ++ + K L S+ E++
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMG-----DSEIFAVIAKKSKVTLSSLMEEL 5494
Score = 35.5 bits (78), Expect = 3.4
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERS 3159
+G D KD I +Y EA HGK L ++ D + + A + +
Sbjct: 2559 SGIDVLWNFKDKEIKPSSKYKIEA---HGKIYKLTVLNMMKDDEGKYTFYAGENITSGKL 2615
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
G + L D+ V + C+V +P K W +DG+ + D
Sbjct: 2616 TVAGG----AISKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESD 2670
Query: 3220 EQFHTLEIAPTNLDDGGVY 3238
L IA T LDD G Y
Sbjct: 2671 GHKRRLIIAATKLDDIGEY 2689
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
T R+P V P P P + ++ EG++V +EC + G P P V W R+
Sbjct: 927 TETARVPAPVEIPVTP----PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRE 979
Score = 35.1 bits (77), Expect = 4.5
Identities = 51/235 (21%), Positives = 105/235 (44%), Gaps = 20/235 (8%)
Query: 1218 KEKIPMFCEIAPQVLQATELVLAKFTKCIDQESNEVEIKDNTLQLKNDQTVRNMSVSKED 1277
+EKIP F A + ++ ++ + A+F +C E E + + + + + TV D
Sbjct: 4330 REKIPRFVHGASRTIKISKPIRAEFIQC-QAEGKERHVSEKSKLHQAEGTVYPF----VD 4384
Query: 1278 EFFTEAIEMETITEQKQTDQTNELVKENIQETSQTDSKDLDVTIEKFGNEEEQK--AKPT 1335
+F I+ E + + KEN+QE +Q+D ++ E+ + K +
Sbjct: 4385 DFSDVTIKKEI---RNNFGKLGRSEKENVQECAQSDYLP-NIHSERISDSYNTKDSSAIV 4440
Query: 1336 DEEIQNEDGHYLVKENKKQ----NKADTEIGKVEKQNKQEVDFVKDQIEMELNEKNASAI 1391
EE E+ HY K+ K + K E G +EK+ + + + + ++++K S
Sbjct: 4441 YEESLGEEIHYPGKKVKHRIIEFEKLHVEKGVLEKRPTR--TSIVNPPQKKIDDKAFSLK 4498
Query: 1392 EEKTETTILPVKLEQ-EQVDERELANKEE--ENRKLEVSTARKKAEADSKKIQEE 1443
+ ++ ++ L + Q E++ ++ N KL S K+ +A ++ QE+
Sbjct: 4499 QRESRSSNLNANMYQAEKMSPNTESDSSNIAINLKLLSSQTHKEFDAQEREQQEK 4553
Score = 34.7 bits (76), Expect = 5.9
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)
Query: 3264 YVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD-- 3321
Y P F L Y L EG+ + + + A P+ +TW+ + + R I+ + D
Sbjct: 3501 YFKPSFTQKLTFKYVL-EGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLH 3559
Query: 3322 -GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
L + V RD+G Y A N G A ++ + VI Q
Sbjct: 3560 HHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ 3602
>AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.
Length = 5604
Score = 86.2 bits (204), Expect = 2e-15
Identities = 64/197 (32%), Positives = 90/197 (45%), Gaps = 12/197 (6%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKK 2643
TL N+ P L T G + C+VIS P ++WY+ LL K K
Sbjct: 3230 TLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLSTGFKC-KF 3287
Query: 2644 LVDGL-ITLEVLNAVPSDSAEYSCTVENENGAISTSANLK------VYPSFEASPIPPTF 2696
L DG TL ++ A P D+A Y+C +N+ G +TSA+L V P E PP
Sbjct: 3288 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAI 3347
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
++DT +CR+ G L K++W+ DK+I R+ + +L I
Sbjct: 3348 ITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAE 3405
Query: 2757 PTPEDSGTYTCKAENSV 2773
PED GTYT A N+V
Sbjct: 3406 AYPEDEGTYTFVASNAV 3422
Score = 81.4 bits (192), Expect = 5e-14
Identities = 88/358 (24%), Positives = 137/358 (38%), Gaps = 35/358 (9%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITL 2651
KPVF +EG + V+ P W+ +G + N ++ + DG +L
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++ A PSDS E++ +N G S S L V + P F +++ + L
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTV--EAVEHQVKPMFVEKLKNVNIKEGSRL 1573
Query: 2712 VLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
++ R G P P I W K+ D +P G L ID+ +DS YT A
Sbjct: 1574 EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1633
Query: 2771 NSVWTDQITHFVNFTGRESQVSPN---VV---TAEKTRIARQSLE--------------- 2809
N D VN ++ P ++ T IA LE
Sbjct: 1634 NKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGD 1693
Query: 2810 ------SRRPHFGNVLTDYQVARGGTIGLQVEIR--GCPTR-VEWLREGRSVTEVYRNAR 2860
++P F LT ++ R G + + G PT VEWL +G+ + E R
Sbjct: 1694 LYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLR 1752
Query: 2861 VFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR 2918
+ E G +L +SG+ TCRA + +G +A + V L + + GR
Sbjct: 1753 MINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGR 1810
Score = 79.8 bits (188), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 78.6 bits (185), Expect = 4e-13
Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 4/208 (1%)
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD- 3211
+L+ +++E Y P F ++ + R +V+G P P+ W+ DG+++V D
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 3212 KRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC 3271
+ +++ +L I P D G + V A+N +G S L V+ + V P F
Sbjct: 1502 THKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE-AVEHQVKPMFVE 1560
Query: 3272 GLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD-RDGQIELALAA 3330
L+ + + EG L + P+ + W ++ + P + + ++ G+ L + +
Sbjct: 1561 KLKNV-NIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDS 1619
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEV 3358
++D+ YT TA N+ GR +T KV V
Sbjct: 1620 TVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 77.8 bits (183), Expect = 6e-13
Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 14/217 (6%)
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDE 3220
V PPQ L+ VQ+ P R + G P PK+SWYK+ E+++ + K+ D
Sbjct: 3233 VNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDG 3291
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP---LY 3277
Q +TL + +D VY A+N+ G + L V+ + V+P+ + P +
Sbjct: 3292 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE--VPEVVSPDQEMPVYPPAIIT 3349
Query: 3278 KLH-----EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
L EG R V + V+WY +++PSR MT D +L +A
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAY 3407
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
D G YT ASN VG+ S++ + + + RI
Sbjct: 3408 PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444
Score = 77.4 bits (182), Expect = 9e-13
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 74.5 bits (175), Expect = 6e-12
Identities = 92/369 (24%), Positives = 141/369 (38%), Gaps = 18/369 (4%)
Query: 3033 ESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++S T G G P F+ P K++ G + C V G P P V W K+G +
Sbjct: 1066 DTSLTEEQAGPGEPA-APYFIT-KPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1123
Query: 3093 EEAGRMTSQFNGF--DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
R +N +C L I DD G Y+ N HG+ S A L + EA
Sbjct: 1124 T-GYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-------LEEA 1175
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +L + E+ Y Q T +++ +V T P + + + + +
Sbjct: 1176 DYELLMKSQQEML--YQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEV-TARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
R +D++FH + + + T + VD V F
Sbjct: 1234 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1293
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
++ Y++ EG + + YP + WY+DG R++ R M +DG+ L +
Sbjct: 1294 DSRIKN-YRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI-R 3388
V D G+YT ASN G A SGK+ V P P + S P + R
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412
Query: 3389 KP-RSSEAR 3396
P R S AR
Sbjct: 1413 SPIRMSPAR 1421
Score = 74.5 bits (175), Expect = 6e-12
Identities = 57/184 (30%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 3201 WYKDGEEVVYD-KRRNKYQDEQ-FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
WYKDG E+ + + R+KY E+ H + I+ T D G Y A N +V+ +
Sbjct: 3179 WYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLY------ 3232
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+ A P+ L+P+ + G R AV+ P ++WY++ L +
Sbjct: 3233 --VNAPEPPQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL- 3288
Query: 3319 DRDGQ-IELALAAVTTRDAGVYTCTASNEVGRASTSGKV-----EVIGTDQTSEPRIPPV 3372
DGQ L L DA VYTC A N+ G A+TS + EV+ DQ P PP
Sbjct: 3289 -HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ-EMPVYPPA 3346
Query: 3373 VISP 3376
+I+P
Sbjct: 3347 IITP 3350
Score = 74.1 bits (174), Expect = 8e-12
Identities = 58/231 (25%), Positives = 97/231 (41%), Gaps = 24/231 (10%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PPT +++ + + LEC I G P P +TW+++D QI S +Q + G+ RL
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 1000
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFV------NFTGRESQVSPNVVTAEKTRIARQ 2806
I EDSG +TC A N T + ++ F + V+ T EK + +
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 2807 SL---------------ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR 2850
+ E P+F ++ GG++ ++ G P V W + G
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 2851 SVTEVYRNARVFVEQ-GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+T YR + +Q G L +S ++G YT + HG +A++
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 69.7 bits (163), Expect = 2e-10
Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 12/197 (6%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ +G+ A + G+P P + W K ++ + +G + L + + +D
Sbjct: 3250 VQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3308
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+CEA N +G A+T A L+V E + ++ V YPP L+D
Sbjct: 3309 YTCEAKNDYGVATTSASLSV-------EVPEVVSPDQEMPV---YPPAIITPLQDTVTSE 3358
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
P R C+V G+ KVSWY +++ + Q E + LEIA +D G Y
Sbjct: 3359 GQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3417
Query: 3242 ARNNSGAVSCHCGLVVD 3258
A N G VS L ++
Sbjct: 3418 ASNAVGQVSSTANLSLE 3434
Score = 68.9 bits (161), Expect = 3e-10
Identities = 60/221 (27%), Positives = 87/221 (39%), Gaps = 28/221 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ GE+ L C + G P P V W + +++E + +G L I++ +D GR
Sbjct: 954 VIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI-ARLMIREAFAEDSGR 1012
Query: 3122 YSCEATNTHGKASTYARLAV------------------------VTDRTVWEADAKLKRE 3157
++C A N G ST LAV V R V D L E
Sbjct: 1013 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1072
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
++ E P T + + V+ V CQV G+P P V W K G + R
Sbjct: 1073 QAGPGEPAAPYFITKPVVQKLVEGG-SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVS 1131
Query: 3218 QDEQFH--TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++Q L I+ T DD G Y + RN G S L+
Sbjct: 1132 YNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLL 1172
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/175 (29%), Positives = 80/175 (45%), Gaps = 26/175 (14%)
Query: 3267 PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIEL 3326
P GL+ + + EG+ + + + YPS VTWYR+ ++ S +T + G L
Sbjct: 943 PTLVSGLKNVTVI-EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARL 1000
Query: 3327 ALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ-------------TSEPRIPPV- 3372
+ D+G +TC+A NE G STS + V +++ T E R
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 3373 -VISPDVPYSKE---------PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ D ++E P FI KP + EG +V+ C+V G+PKP VYW
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115
Score = 66.1 bits (154), Expect = 2e-09
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G PT V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 64.5 bits (150), Expect = 6e-09
Identities = 31/95 (32%), Positives = 47/95 (49%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + L + T +EG V L C + PTVTWYR +++ + ++ G+ L +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
A DS ++C+ NE G +STS L V S E
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 1037
Score = 64.1 bits (149), Expect = 8e-09
Identities = 107/483 (22%), Positives = 195/483 (40%), Gaps = 51/483 (10%)
Query: 2819 LTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTE 2877
L + V G ++ L+ I G P+ V W RE + E + ++ + G+ L + +
Sbjct: 949 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSIDFQITFQSGIARLMIREAFA 1007
Query: 2878 TESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGR---PEKDILIS---VGEDI 2931
+SG +TC A + G V + + V + + + + + EK + S V D
Sbjct: 1008 EDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDT 1067
Query: 2932 NISFRTQGEPKPKA--------VPERIPGEPCVVD---GGNNWVSLAWPKSD-PQTTAPV 2979
+++ G +P A V + + G V GGN + W KS P TT
Sbjct: 1068 SLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTG-- 1125
Query: 2980 LAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSS 3039
YKV + G + + +T F GE + + RN++ GE+S ++S
Sbjct: 1126 YRYKVS---YNKQTGECKLVISMT-------FADDAGE---YTIVVRNKH--GETSASAS 1170
Query: 3040 SIGVGLAGDRPEFVDILPGQLKIL--AGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
+ + ++ ++ Q ++L TA + G+ PG V+ + E E+E
Sbjct: 1171 LL------EEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQAL 1224
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ + D + ++D+ + K Y R+ T + E D + K
Sbjct: 1225 IRKKM-AKD--TVVVRTYVEDQEFHISSFEERLIKEIEY-RIIKTTLEELLEEDGEEKMA 1280
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNK 3216
F R+++ R+ V C++ G P PK++WYKDG+ + + +R +
Sbjct: 1281 VDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1340
Query: 3217 YQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
+ + +L I +D G+Y A N G C L V+ AP + LEP+
Sbjct: 1341 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPA-APLGAPTYIPTLEPV 1399
Query: 3277 YKL 3279
++
Sbjct: 1400 SRI 1402
Score = 62.9 bits (146), Expect = 2e-08
Identities = 75/354 (21%), Positives = 142/354 (40%), Gaps = 23/354 (6%)
Query: 2571 KAFSEARSVISEKRTLSRNSTR--KPVFSTFLTD---RTAVEGSRVKLTCSVISSSDPTV 2625
K F E+R V+ +L+ +P F+T + VEG V C V + P V
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113
Query: 2626 TWYRNGVLLDNKLKYRKKL--VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
W ++GV L +Y+ G L + D+ EY+ V N++G S SA+L
Sbjct: 1114 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1173
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAE-NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA 2742
+E +S ++ + + V E ++ G+ P + + +K+ + QA
Sbjct: 1174 EADYE------LLMKSQQEMLYQTQVTAFVQEPKV-GETAPGFVYSEYEKEYEKE---QA 1223
Query: 2743 FYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
+ ED + E + +I + + T E + + EK
Sbjct: 1224 LIRKKMAKDTVVVRTYVEDQEFHISSFEERL-IKEIEYRIIKTTLEELLEED--GEEKMA 1280
Query: 2803 IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARV 2861
+ E+ F + + +Y++ G + ++ G P ++ W ++G+ + R
Sbjct: 1281 VDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMD 1340
Query: 2862 FVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVI 2915
F++ G +L + V + G+YT A + GN + + V+P+ G P I
Sbjct: 1341 FLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL-YVEPAAPLGAPTYI 1393
Score = 62.1 bits (144), Expect = 3e-08
Identities = 64/239 (26%), Positives = 105/239 (43%), Gaps = 33/239 (13%)
Query: 2688 EASPIPPTFTRSIRDTFHLAEN-ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E +PP F I D F + EN + V +C + G P P++ W+K+ I D
Sbjct: 5374 EVFEMPPRFIMPICD-FKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEE 5432
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
G L I N DS TY C+A N V F+ T +S++ V A+K+++
Sbjct: 5433 KGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL--TMGDSEIF--AVIAKKSKVTLS 5488
Query: 2807 SLESR---RPHFGNVLTDYQVARG---------------GTIG-LQVEIRGCP-TRVEWL 2846
SL + ++ + ++QV G GT Q +RG P V W
Sbjct: 5489 SLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWY 5548
Query: 2847 REGRSVTEVYRNARVFVEQ---GLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
++G+ V + R VE+ G + L ++ + +++ G Y C A + G + AA+T+
Sbjct: 5549 KDGKLV----QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 59.3 bits (137), Expect = 2e-07
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 18/149 (12%)
Query: 3273 LEPL-YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P+ +K EG R V P W+ DG ++ + + DG L +
Sbjct: 1461 LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPA 1520
Query: 3332 TTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
T D+G +T A N GR+S + VI T + E ++ +PMF+ K +
Sbjct: 1521 TPSDSGEWTVVAQNRAGRSS----ISVILTVEAVEHQV-------------KPMFVEKLK 1563
Query: 3392 SSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ +EG + ++ G+P PD+ WL++
Sbjct: 1564 NVNIKEGSRLEMKVRATGNPNPDIVWLKN 1592
Score = 59.3 bits (137), Expect = 2e-07
Identities = 27/79 (34%), Positives = 43/79 (54%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C + P VTW++NGVLL K++ + V+ L + + DS +Y C
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKC 4231
Query: 2667 TVENENGAISTSANLKVYP 2685
EN +GA+ + ++L V P
Sbjct: 4232 VAENNSGAVESVSDLTVEP 4250
Score = 59.3 bits (137), Expect = 2e-07
Identities = 60/217 (27%), Positives = 81/217 (37%), Gaps = 23/217 (10%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
KI A CSV G P P V W K +E + + L I+++ + D
Sbjct: 5390 KIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSA 5449
Query: 3121 RYSCEATNTHGKA--------------STYARLAVVTDRTVWEADAKLKRERSAE----- 3161
Y C A N G+A + A+ + VT ++ E + LK +
Sbjct: 5450 TYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLME-ELVLKSNYTDSFFEFQ 5508
Query: 3162 -VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
VEG PP+F + D C V GSP P V WYKDG+ V + +
Sbjct: 5509 VVEG--PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGT 5566
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
FH L I D G Y A N SG L +
Sbjct: 5567 GFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/277 (24%), Positives = 115/277 (41%), Gaps = 32/277 (11%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRYS 3123
G A+ V GKP P W KNG ++E + R+ + + C L I+D+ +D
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIER-SDRIYWYWPEDNVCELVIRDVTAEDSASIM 2150
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
+A N G+ S++A L V AK + E++ + +++ AT+
Sbjct: 2151 VKAINIAGETSSHAFLLV---------QAKQLITFTQELQD-------VVAKEKDTMATF 2194
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C+ P KV WYKDG EV + + D + H L I + D Y
Sbjct: 2195 E----CET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+ V L+V+ + EF L+ + ++ E + +V ++ WY
Sbjct: 2250 EDEN-VKTTAKLIVEGAV-----VEFVKELQDI-EVPESYSGELECIVSP-ENIEGKWYH 2301
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
+ V L+ + + +T R G+ L + VT D G Y+
Sbjct: 2302 NDVELKSNGKYTIT-SRRGRQNLTVKDVTKEDQGEYS 2337
Score = 58.8 bits (136), Expect = 3e-07
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 35/222 (15%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-FH 3223
+ PP+F M + D ++ C VIG P P+V WYK+ + D + +E+ H
Sbjct: 5377 EMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV-DKGIRAYVAPEFCCGLEPL------ 3276
TL+I L D Y A N G C L + D I A +A + L L
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496
Query: 3277 ----------YKLHEGDELRISAVVEAYPSVG----------------VTWYRDGVRLRP 3310
+++ EG I + + Y +G V WY+DG +L
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDG-KLVQ 5555
Query: 3311 SRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
RR + G L + ++ D G Y C A+N+ G A +
Sbjct: 5556 GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAES 5597
Score = 58.0 bits (134), Expect = 6e-07
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 57.2 bits (132), Expect = 1e-06
Identities = 90/397 (22%), Positives = 152/397 (38%), Gaps = 56/397 (14%)
Query: 3076 GKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAS 3134
G P V W+ +G +E RM ++F G+ C L D G +C ATN +G
Sbjct: 1730 GDPTMVVEWLHDGKPLEAANRLRMINEF-GY-CSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 3135 TYARLAVVTDRTVWEA----DAKLKRERSAEVEG----------------DYPPQFTMRL 3174
T A L V ++++ E + + +R E+E P +
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1847
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
RV R C+V G P PKV+WY +G +++ +R + + + H L+I D
Sbjct: 1848 EPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIHYLDIVDCKSYD 1906
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVD--KGIRAYV--APEFCCGLEPLYKLHEGDELRISAV 3290
G +VTA N G + L + + R+ + APE P + +HE +L+ V
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPE----PRPEFHVHEPGKLQFE-V 1961
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV-GR 3349
+ V T ++ V+L+ + R + EL + G Y + E+ R
Sbjct: 1962 QKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSR 2021
Query: 3350 ASTSGKVEVIG-------------TDQ-----TSEPRIPPVVISPD----VPYSKEPMFI 3387
E++ T++ E +I PD P + P
Sbjct: 2022 KKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF 2081
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+ +S +G VVG P P+ W ++ +K+
Sbjct: 2082 ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2118
Score = 56.4 bits (130), Expect = 2e-06
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 5/99 (5%)
Query: 3045 LAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNG 3104
+ + P+ + +P + G++ L C + G+P P V W +NG +++ QF
Sbjct: 4153 ITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQ---NQKFQFEE 4209
Query: 3105 FDCC--LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+C L IKD+N D G+Y C A N G + + L V
Sbjct: 4210 VNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 8/194 (4%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY-QDEQFHTLE 3226
P+ R++ + V +V+G P P+ WYK+G ++ R Y ++ L
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I +D V A N +G S H L+V +A F L+ + E D +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQLITFTQELQDVV-AKEKDTMA 2192
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ P V V WY+DG+ + + M DR L++ + T DA Y+C E
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHF-LSILTIDTSDAEDYSCVLV-E 2250
Query: 3347 VGRASTSGKVEVIG 3360
T+ K+ V G
Sbjct: 2251 DENVKTTAKLIVEG 2264
Score = 54.0 bits (124), Expect = 9e-06
Identities = 54/214 (25%), Positives = 90/214 (42%), Gaps = 25/214 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDC 3107
+P FV + P K L G+TA V G+P+P W +G + V + ++ + +G
Sbjct: 1456 KPVFV-LKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ- 1513
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I D G ++ A N G++S L V EA VE
Sbjct: 1514 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV-------EA-----------VEHQVK 1555
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVV---YDKRRNKYQDEQFHT 3224
P F +L++ ++ + + + G+P P + W K+ + +V Y K R + +
Sbjct: 1556 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE-AA 1614
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
L+I T D Y TA N +G + C + V+
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648
Score = 52.4 bits (120), Expect = 3e-05
Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F++ L + K+ T V+G PVPGV W +N +E + R+ + G C L
Sbjct: 5183 PSFIEPLTKR-KVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDE-RIKMERVGNVCSL 5240
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I +I + G Y C A N G+A ++A + ++
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 52.0 bits (119), Expect = 4e-05
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQF--- 3222
PP+ + + R + + L C + G P P V+W+++G V K+ K+Q E+
Sbjct: 4157 PPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNG---VLLKQNQKFQFEEVNCS 4213
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
H L I N D G Y+ A NNSGAV L V+
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVE 4249
Score = 51.6 bits (118), Expect = 5e-05
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK-Y 2640
+K LS + +F + +T +GS V+ DP WY+NGV ++ + Y
Sbjct: 2067 DKIELSPSMEAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2125
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSI 2700
D + L + + DSA N G S+ A L V +A + TFT+ +
Sbjct: 2126 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV----QAKQL-ITFTQEL 2180
Query: 2701 RDTFHLAENEL-VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+D ++ + EC +P K+ W+KD ++ +Y+ + V L+I
Sbjct: 2181 QDVVAKEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSDRKVHFLSILTIDT 2238
Query: 2760 EDSGTYTC 2767
D+ Y+C
Sbjct: 2239 SDAEDYSC 2246
Score = 51.2 bits (117), Expect = 6e-05
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T + +KP + +EG + C V P V WY NG L+ ++R +
Sbjct: 1832 TTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR- 1890
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
DG+ L++++ D+ E T EN G I L++
Sbjct: 1891 YDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 50.0 bits (114), Expect = 1e-04
Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Query: 2588 RNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG 2647
+++ P F LT R E + + V P V WYRN LL+ + + + V
Sbjct: 5177 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 5236
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE-ASPIPPTFT 2697
+ +LE+ N + EY C N G + AN+ + P E +PP T
Sbjct: 5237 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVT 5287
Score = 50.0 bits (114), Expect = 1e-04
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 5/103 (4%)
Query: 3273 LEPLYK--LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALA 3329
+EPL K ++E L VE P GV WYR+ L P R + ++R G + L ++
Sbjct: 5186 IEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDER--IKMERVGNVCSLEIS 5243
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPV 3372
+ + G Y C A N +G A + V+++ ++ PPV
Sbjct: 5244 NIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPV 5286
Score = 48.8 bits (111), Expect = 3e-04
Identities = 49/257 (19%), Positives = 94/257 (36%), Gaps = 7/257 (2%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F + + V C G P P V+WY + + ++ + E + L
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILT 4002
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
++ + + G N G V L V +A + P++ + +E
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKV----KAKQKHDVKAHKVPVFHDYLDEEEE 4058
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTR-DAGVYTCTASN 3345
++ V + + ++G + + G EL V + A
Sbjct: 4059 LALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQDK 4118
Query: 3346 EVGRASTSGKVE--VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVII 3403
E + ++E + DQ ++ V D+ M P+ + REGD++I+
Sbjct: 4119 ESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIIL 4178
Query: 3404 ECEVVGDPKPDVYWLRD 3420
EC + G+P+P V W ++
Sbjct: 4179 ECLISGEPQPVVTWFQN 4195
Score = 48.4 bits (110), Expect = 5e-04
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-- 3223
+ P FT +L + V PV TC++I P P+++W+ + + RR + H
Sbjct: 3502 FKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHH 3561
Query: 3224 --TLEIAPTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKG 3260
+LEI D G Y + A N+ G A S LV+ KG
Sbjct: 3562 SSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKG 3601
Score = 48.0 bits (109), Expect = 6e-04
Identities = 40/143 (27%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT-VENENGAISTSANLKV 2683
V WY++G+ + KYR + L +L SD+ +YSC VE+EN + T+A L V
Sbjct: 2205 VKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN--VKTTAKLIV 2262
Query: 2684 YPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
E + + F + ++D LEC + + + + W+ +D ++ S+G+Y
Sbjct: 2263 ----EGAVV--EFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKY-TI 2314
Query: 2744 YLADGVCRLAIDNPTPEDSGTYT 2766
G L + + T ED G Y+
Sbjct: 2315 TSRRGRQNLTVKDVTKEDQGEYS 2337
Score = 48.0 bits (109), Expect = 6e-04
Identities = 37/123 (30%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 2565 DMRHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
D+ H+S A S IS T S KP F+ LT + +EG V TC +I+ P
Sbjct: 3477 DIDHKSMAAKRYASRISS--TSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPE 3534
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGL----ITLEVLNAVPSDSAEYSCTVENENGAISTSAN 2680
+TW+ N + L+ K L +LE+ DS Y N G+ ++A+
Sbjct: 3535 MTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTAS 3594
Query: 2681 LKV 2683
L V
Sbjct: 3595 LLV 3597
Score = 47.6 bits (108), Expect = 8e-04
Identities = 22/64 (34%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ ++LEC I G+P P +TWF++ + + ++Q F + +L I + +DSG Y C
Sbjct: 4174 DSIILECLISGEPQPVVTWFQNGVLLKQNQKFQ-FEEVNCSHQLYIKDVNSQDSGKYKCV 4232
Query: 2769 AENS 2772
AEN+
Sbjct: 4233 AENN 4236
Score = 47.6 bits (108), Expect = 8e-04
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 1/85 (1%)
Query: 2687 FEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
F+ PP F + I D + +C +RG P P + W+KD K + R+
Sbjct: 5507 FQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRRFTVEESG 5565
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAEN 2771
G L I + D G Y C A N
Sbjct: 5566 TGFHNLFITSLVKSDEGEYRCVATN 5590
Score = 46.8 bits (106), Expect = 0.001
Identities = 27/88 (30%), Positives = 41/88 (46%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F ++D A G+ C V S PTV WY++G L+ + ++ G L +
Sbjct: 5514 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFI 5573
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANL 2681
+ V SD EY C N++G + A L
Sbjct: 5574 TSLVKSDEGEYRCVATNKSGMAESFAAL 5601
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P T L D EG + C V S +D V+WY + +R + LE+
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
A P D Y+ N G +S++ANL +
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 8/137 (5%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
+++ PS EA P F R T ++ R+ G+P P+ W+K+ +I R
Sbjct: 2069 IELSPSMEA---PKIFERIQSQTVGQG-SDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2124
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE----SQVSPNVV 2796
++ D VC L I + T EDS + KA N F+ ++ +Q +VV
Sbjct: 2125 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVV 2184
Query: 2797 TAEKTRIARQSLESRRP 2813
EK +A E+ P
Sbjct: 2185 AKEKDTMATFECETSEP 2201
Score = 44.8 bits (101), Expect = 0.006
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
Score = 44.8 bits (101), Expect = 0.006
Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 18/162 (11%)
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+K+ E + V P+ V WY++ + + P + + G L + V D+
Sbjct: 5389 FKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDS 5448
Query: 3337 GVYTCTASNEVGRA-----STSGKVEVIG-----TDQTSEPRIPPVVISPDVPYS----- 3381
Y C A N VG A T G E+ + T + +V+ + S
Sbjct: 5449 ATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQ 5508
Query: 3382 ---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P FI+ A G +C V G P+P VYW +D
Sbjct: 5509 VVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKD 5550
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
+P+ V + P +++L GETA C V G P P V W NG ++ ++ R +++G
Sbjct: 1840 KPDIV-LYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNG-QLIRKSKRFRVRYDGIH-Y 1896
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I D D G A N G +L +
Sbjct: 1897 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929
Score = 44.0 bits (99), Expect = 0.010
Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 16/212 (7%)
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
D +K VEG +F L+D V +Y L C ++ + WY + E+
Sbjct: 2251 DENVKTTAKLIVEGAVV-EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKS 2308
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+ + L + +D G Y C L + A +
Sbjct: 2309 NGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT----CKLKMKPRPIAILQ---- 2360
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
GL K+ EGD +++ V GV W +DG ++PS R + +D+ + L +
Sbjct: 2361 -GLSD-QKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHM-LLIED 2416
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
+T DAG Y+ T +G STSG+V V D
Sbjct: 2417 MTKEDAGNYSFTIP-ALG-LSTSGRVSVYSVD 2446
Score = 43.2 bits (97), Expect = 0.017
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L+D+ EG V+L V S V W ++G + + + L + +
Sbjct: 2362 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKE 2420
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D+ YS T+ +STS + VY +P+ +D + + VLEC++
Sbjct: 2421 DAGNYSFTIPALG--LSTSGRVSVYSVDVITPL--------KDVNVIEGTKAVLECKVSV 2470
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ + W+ +D+QI D R QA + RL I+ D G Y
Sbjct: 2471 PDVTSVKWYLNDEQIKPDDRVQAI-VKGTKQRLVINRTHASDEGPY 2515
Score = 42.7 bits (96), Expect = 0.022
Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P F ++ G T +++ G P W +G+ + Y + V E G +L
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGED 2930
+ T ++SG +T A + G ++ +T V+ + KP + K++ I G
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFV--EKLKNVNIKEGSR 1572
Query: 2931 INISFRTQGEPKPKAV 2946
+ + R G P P V
Sbjct: 1573 LEMKVRATGNPNPDIV 1588
Score = 42.7 bits (96), Expect = 0.022
Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ + Q ++ G++ N C +G P P V W N + + + L
Sbjct: 3944 PSFLQEIESQ-EVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYS-IL 4001
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T+ ++ +EG +C N +G T + L V
Sbjct: 4002 TLSSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
Score = 42.3 bits (95), Expect = 0.030
Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 8/90 (8%)
Query: 3278 KLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAG 3337
+ EGD + + ++ P VTW+++GV L+ +++ + + +L + V ++D+G
Sbjct: 4169 RCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQK-FQFEEVNCSHQLYIKDVNSQDSG 4227
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
Y C A N SG VE + +D T EP
Sbjct: 4228 KYKCVAEN------NSGAVESV-SDLTVEP 4250
Score = 42.3 bits (95), Expect = 0.030
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLITLE 2652
P F + D E S CSVI P V WY+ + ++ + +KY G TL+
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 2653 VLNAVPSDSAEYSCTVEN 2670
+ N SDSA Y C N
Sbjct: 5440 IRNVCLSDSATYRCRAVN 5457
Score = 40.7 bits (91), Expect = 0.090
Identities = 25/91 (27%), Positives = 37/91 (40%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP L++ V V L C + G P P V+WY++ ++ L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G + +A N +G VS C L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 40.7 bits (91), Expect = 0.090
Identities = 57/251 (22%), Positives = 92/251 (36%), Gaps = 27/251 (10%)
Query: 2714 ECRIR--GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
ECR+ G P + W D K + + R + G C L DSG TC+A N
Sbjct: 1723 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATN 1781
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG---NVLTD------- 2821
TD + + +S V + + + + R R H G V TD
Sbjct: 1782 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1841
Query: 2822 --------YQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
+V G T + + G P +V W G+ + + R RV + G++ L +
Sbjct: 1842 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR-FRVRYD-GIHYLDI 1899
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
D ++G A + G ++ + + Q D +V+ PE V E
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF---RSVLRRAPEPRPEFHVHEPGK 1956
Query: 2933 ISFRTQGEPKP 2943
+ F Q +P
Sbjct: 1957 LQFEVQKVDRP 1967
Score = 40.3 bits (90), Expect = 0.12
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 3147 VWEADA-KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDG 3205
+W +D+ E + + PP F L R+V + +V G P P V WY++
Sbjct: 5161 IWRSDSFGTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNK 5220
Query: 3206 EEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
+ D+R + +LEI+ +GG Y A N G
Sbjct: 5221 SLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIG 5262
Score = 39.9 bits (89), Expect = 0.16
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 17/169 (10%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D E +L C ++S + WY N V L + KY G L V +
Sbjct: 2273 LQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKE 2331
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIR 2718
D EYS ++ + T+ LK+ P P + + D + E ++V LE ++
Sbjct: 2332 DQGEYSFVIDGK----KTTCKLKM------KPRPIAILQGLSDQ-KVCEGDIVQLEVKVS 2380
Query: 2719 GQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
+ + + W KD +++ PSD + + L I++ T ED+G Y+
Sbjct: 2381 LESVEGV-WMKDGQEVQPSDRVH--IVIDKQSHMLLIEDMTKEDAGNYS 2426
Score = 39.9 bits (89), Expect = 0.16
Identities = 46/185 (24%), Positives = 76/185 (41%), Gaps = 20/185 (10%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLN 2655
T L D +EG++ L C V +V WY N + D+++ + +V G V+N
Sbjct: 2449 TPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVIN 2505
Query: 2656 AV-PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLE 2714
SD Y V G + T+ NL V E I R +RD +V E
Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSV----EKIKI----IRGLRDLTCTETQNVVFE 2553
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
+ + + W DK+I +Y+ + +L + N +D G YT A ++
Sbjct: 2554 VELSHSGI-DVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEGKYTFYAGENMT 2611
Query: 2775 TDQIT 2779
+ ++T
Sbjct: 2612 SGKLT 2616
Score = 39.9 bits (89), Expect = 0.16
Identities = 45/187 (24%), Positives = 74/187 (39%), Gaps = 21/187 (11%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L + T E T + + V W +NGV+L++ KY + + +L + N
Sbjct: 2713 LKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIV 2772
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D + Y + G + SA L V E I + +D L + E +
Sbjct: 2773 DESVYGFRL----GRLGASARLHV----ETVKI----IKKPKDVTALENATVAFEVSVSH 2820
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT-------CKAENS 2772
+P + WF +I +++ V +L + N +P D+G YT CKA+
Sbjct: 2821 DTVP-VKWFHKSVEIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLF 2878
Query: 2773 VWTDQIT 2779
V T IT
Sbjct: 2879 VETLHIT 2885
Score = 39.9 bits (89), Expect = 0.16
Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 13/141 (9%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY-- 2868
+P F LT V G + + CPT + W R + R + E L+
Sbjct: 3503 KPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRI-IKAESDLHHH 3561
Query: 2869 --TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEK----- 2921
+L + V + +SG Y A ++ G+ + A++ V+Q D K + R E+
Sbjct: 3562 SSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ-DEKYLEFLKRAERTHENV 3620
Query: 2922 DILISVGED-INISFRTQGEP 2941
+ L+ GED I + R G P
Sbjct: 3621 EALVERGEDRIKVDLRFTGSP 3641
Score = 39.9 bits (89), Expect = 0.16
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 4/97 (4%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM---TSQFNGF 3105
+P F L + +L GE TC + P P + W N + R+ S +
Sbjct: 3503 KPSFTQKLTFKY-VLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHH 3561
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L IK + D G Y A N+ G A + A L V+
Sbjct: 3562 SSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVI 3598
Score = 39.5 bits (88), Expect = 0.21
Identities = 15/38 (39%), Positives = 23/38 (60%)
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+P+F+ KP S + EG T + +VVG P P+ +W D
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1493
Score = 39.5 bits (88), Expect = 0.21
Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 5/123 (4%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD---GVC 2750
P+FT+ + + L +V CR+ P P++TWF +++ IP+ R +D
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWTDQITH--FVNFTGRESQVSPNVVTAEKTRIARQSL 2808
L I DSG+Y A NS + + T V G++ + + AE+T ++L
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAERTHENVEAL 3623
Query: 2809 ESR 2811
R
Sbjct: 3624 VER 3626
Score = 39.1 bits (87), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+F ++D +V C+V P V W KD +E+ R +++ H L I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIP 3117
Query: 3229 PTNLDDGGVYEVTARNN 3245
T + D G Y V A N
Sbjct: 3118 STRMSDAGKYTVVAGGN 3134
Score = 39.1 bits (87), Expect = 0.28
Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 3/105 (2%)
Query: 2686 SFEASP--IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF 2743
SF P PP+F + I + C +G P P +TW+ +D IP + +
Sbjct: 3934 SFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNF-II 3992
Query: 2744 YLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRE 2788
+ + L + + ++ G+ TC N T + T + ++
Sbjct: 3993 HSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQ 4037
Score = 38.7 bits (86), Expect = 0.36
Identities = 65/299 (21%), Positives = 109/299 (36%), Gaps = 40/299 (13%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH-EVEEEAGRMTSQFNGFDC 3107
+P FV+ L + I G + G P P +VW+KN V + ++ + +
Sbjct: 1555 KPMFVEKLKN-VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1613
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL----KRERSAEV- 3162
L I D Y+ A N G+ +T ++ V + E + KL R+ E+
Sbjct: 1614 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1673
Query: 3163 -----------------EGD-------YPPQFTMRLRDRRVQATYPVRLTCQV--IGSPP 3196
EGD P F +L R++ P C++ IG P
Sbjct: 1674 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPT 1733
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
V W DG+ + R + + +L+ D G+ A N G L+
Sbjct: 1734 MVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Query: 3257 V--DKG-IRAYVAPEFCCGLEPLYKL----HEGDELRISAVVEAYPSVGVTWYRDGVRL 3308
V +K + PE GL+ + +L HEG ++ + + Y + VR+
Sbjct: 1794 VKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1852
Score = 38.3 bits (85), Expect = 0.48
Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
+PP+F + L + G P+P + W+++ + D R + + + VC
Sbjct: 5181 MPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN-VCS 5239
Query: 2752 LAIDNPTPEDSGTYTCKAENSV 2773
L I N + G Y C A N +
Sbjct: 5240 LEISNIQKGEGGEYMCHAVNII 5261
Score = 37.1 bits (82), Expect = 1.1
Identities = 19/90 (21%), Positives = 35/90 (38%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F + + EG C P VTWY N + + + ++ L +
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + +C + N+ G + T++ LKV
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
Score = 37.1 bits (82), Expect = 1.1
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F LT +V T+G VE+ G P V+W R +S+ E ++ + +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYR-NKSLLEPDERIKMERVGNVCSLE 5241
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+S++ + E G Y C A + G A + ++
Sbjct: 5242 ISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 36.3 bits (80), Expect = 1.9
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 3049 RPEFVDILPG--QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFD 3106
+P + IL G K+ G+ L V + V GV WMK+G EV + + R+ +
Sbjct: 2352 KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEV-QPSDRVHIVIDKQS 2409
Query: 3107 CCLTIKDINIDDEGRYS----CEATNTHGKASTYA 3137
L I+D+ +D G YS +T G+ S Y+
Sbjct: 2410 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS 2444
Score = 35.9 bits (79), Expect = 2.6
Identities = 26/120 (21%), Positives = 52/120 (43%), Gaps = 6/120 (5%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F + D+++ + + G PT V+W +E + + E+G +TL
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
+ +V ++S Y CRA + G +T+ D + ++ + K L S+ E++
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMG-----DSEIFAVIAKKSKVTLSSLMEEL 5494
Score = 35.5 bits (78), Expect = 3.4
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 3103 NGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERS 3159
+G D KD I +Y EA HGK L ++ D + + A + +
Sbjct: 2559 SGIDVLWNFKDKEIKPSSKYKIEA---HGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKL 2615
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
G + L D+ V + C+V +P K W +DG+ + D
Sbjct: 2616 TVAGG----AISKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESD 2670
Query: 3220 EQFHTLEIAPTNLDDGGVY 3238
L IA T LDD G Y
Sbjct: 2671 GHKRRLIIAATKLDDIGEY 2689
Score = 35.1 bits (77), Expect = 4.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
T R+P V P P P + ++ EG++V +EC + G P P V W R+
Sbjct: 927 TETARVPAPVEIPVTP----PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRE 979
Score = 35.1 bits (77), Expect = 4.5
Identities = 51/235 (21%), Positives = 105/235 (44%), Gaps = 20/235 (8%)
Query: 1218 KEKIPMFCEIAPQVLQATELVLAKFTKCIDQESNEVEIKDNTLQLKNDQTVRNMSVSKED 1277
+EKIP F A + ++ ++ + A+F +C E E + + + + + TV D
Sbjct: 4330 REKIPRFVHGASRTIKISKPIRAEFIQC-QAEGKERHVSEKSKLHQAEGTVYPF----VD 4384
Query: 1278 EFFTEAIEMETITEQKQTDQTNELVKENIQETSQTDSKDLDVTIEKFGNEEEQK--AKPT 1335
+F I+ E + + KEN+QE +Q+D ++ E+ + K +
Sbjct: 4385 DFSDVTIKKEI---RNNFGKLGRSEKENVQECAQSDYLP-NIHSERISDSYNTKDSSAIV 4440
Query: 1336 DEEIQNEDGHYLVKENKKQ----NKADTEIGKVEKQNKQEVDFVKDQIEMELNEKNASAI 1391
EE E+ HY K+ K + K E G +EK+ + + + + ++++K S
Sbjct: 4441 YEESLGEEIHYPGKKVKHRIIEFEKLHVEKGVLEKRPTR--TSIVNPPQKKIDDKAFSLK 4498
Query: 1392 EEKTETTILPVKLEQ-EQVDERELANKEE--ENRKLEVSTARKKAEADSKKIQEE 1443
+ ++ ++ L + Q E++ ++ N KL S K+ +A ++ QE+
Sbjct: 4499 QRESRSSNLNANMYQAEKMSPNTESDSSNIAINLKLLSSQTHKEFDAQEREQQEK 4553
Score = 34.7 bits (76), Expect = 5.9
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)
Query: 3264 YVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD-- 3321
Y P F L Y L EG+ + + + A P+ +TW+ + + R I+ + D
Sbjct: 3501 YFKPSFTQKLTFKYVL-EGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLH 3559
Query: 3322 -GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
L + V RD+G Y A N G A ++ + VI Q
Sbjct: 3560 HHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ 3602
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 85.4 bits (202), Expect = 3e-15
Identities = 88/337 (26%), Positives = 134/337 (39%), Gaps = 43/337 (12%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP FV P L + ++A C +G PVP V W K+ E+ + + D
Sbjct: 260 ERPSFVK-RPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD-----DH 313
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I+ + D G Y+C A N GKA A L TV E P
Sbjct: 314 TLKIRKVTAGDMGSYTCVAENMVGKAEASATL------TVQE-----------------P 350
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY-----DKRRNKYQDEQF 3222
P F ++ RD+ V V C+ G+P P + W ++G + + + +++ Q
Sbjct: 351 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 410
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
L I D G Y N +G++ L V I P G P+ +
Sbjct: 411 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG--PVNQTVAV 468
Query: 3283 D-ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
D +S V P + W +DGV + I L+ +G +++ A + D G YTC
Sbjct: 469 DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVLQIRYAKL--GDTGRYTC 525
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV 3378
AS G A+ S +EV + P PP P++
Sbjct: 526 IASTPSGEATWSAYIEV---QEFGVPVQPPRPTDPNL 559
Score = 78.6 bits (185), Expect = 4e-13
Identities = 97/396 (24%), Positives = 153/396 (38%), Gaps = 65/396 (16%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHE 3090
GE+ ++S+ V + D +F P + + GE A + C +G P P + W K+G
Sbjct: 154 GEAVSHNASLEVAILRD--DFRQN-PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSP 210
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
++++ R+T + T K D G+Y C TN G+ R + V + TV E
Sbjct: 211 LDDKDERITIRGGKLMITYTRKS----DAGKYVCVGTNMVGE-----RESEVAELTVLER 261
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
+ +KR + V D +F C+ G P P V W KD E+
Sbjct: 262 PSFVKRPSNLAVTVDDSAEFK-----------------CEARGDPVPTVRWRKDDGEL-- 302
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+++Y+ HTL+I D G Y A N G L V + V P
Sbjct: 303 --PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPR-- 358
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR------LRPSRRAIMTLDRDGQI 3324
+ + L G + P + W R+G + P + ++ + G
Sbjct: 359 ---DQVVAL--GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG-- 411
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEP 3384
+L + V D G Y C N G T +EV TD ++ R PPV+ V
Sbjct: 412 DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV--TDVIAD-RPPPVIRQGPV------ 462
Query: 3385 MFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ A +G T ++ C G P P + W +D
Sbjct: 463 ------NQTVAVDG-TFVLSCVATGSPVPTILWRKD 491
Score = 75.8 bits (178), Expect = 3e-12
Identities = 101/372 (27%), Positives = 137/372 (36%), Gaps = 66/372 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE-----AGRMTSQFNG-FDCCLT 3110
P L + GE A L C +G+P P + W K G VE + + RM F +
Sbjct: 74 PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIV 133
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ DEG Y C A N G+A ++ +A L+ A + D F
Sbjct: 134 HGRKSRPDEGVYVCVARNYLGEAVSH--------------NASLE---VAILRDD----F 172
Query: 3171 TMRLRDRRVQATYPVRLTCQ-VIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D V P + CQ G P P +SW KDG + R + + L I
Sbjct: 173 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK---LMITY 229
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRIS 3288
T D G Y N G + P F L + + E +
Sbjct: 230 TRKSDAGKYVCVGTNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCE 284
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
A + P+ V W +D L SR I RD L + VT D G YTC A N VG
Sbjct: 285 ARGDPVPT--VRWRKDDGELPKSRYEI----RDDH-TLKIRKVTAGDMGSYTCVAENMVG 337
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVV 3408
+A S + V EP P F+ KPR G TV +CE
Sbjct: 338 KAEASATLTV------QEP----------------PHFVVKPRDQVVALGRTVTFQCEAT 375
Query: 3409 GDPKPDVYWLRD 3420
G+P+P ++W R+
Sbjct: 376 GNPQPAIFWRRE 387
Score = 72.1 bits (169), Expect = 3e-11
Identities = 89/353 (25%), Positives = 141/353 (39%), Gaps = 57/353 (16%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL----DNKLKYRKKLVDG-LITLEVLN 2655
+D +G L C PT+ WY+ G + D+ +R L G L L +++
Sbjct: 75 SDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVH 134
Query: 2656 AVPS--DSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
S D Y C N G A+S +A+L E + + F ++ D V
Sbjct: 135 GRKSRPDEGVYVCVARNYLGEAVSHNASL------EVAILRDDFRQNPSDVMVAVGEPAV 188
Query: 2713 LECR-IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+EC+ RG P P I+W KD P D + + + G +L I D+G Y C N
Sbjct: 189 MECQPPRGHPEPTISWKKDGS--PLDDKDERITIRGG--KLMITYTRKSDAGKYVCVGTN 244
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V RES+V AE T + R S R + + D +
Sbjct: 245 MVGE-----------RESEV------AELTVLERPSFVKRPSNLAVTVDD-------SAE 280
Query: 2832 LQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ E RG P V W ++ + + +R + +TL + VT + G YTC A +
Sbjct: 281 FKCEARGDPVPTVRWRKDDGELPK----SRYEIRDD-HTLKIRKVTAGDMGSYTCVAENM 335
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G + +A +TV +P KP +D ++++G + G P+P
Sbjct: 336 VGKAEASATLTVQEPPHFVVKP--------RDQVVALGRTVTFQCEATGNPQP 380
Score = 64.9 bits (151), Expect = 5e-09
Identities = 81/329 (24%), Positives = 134/329 (40%), Gaps = 50/329 (15%)
Query: 2622 DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTS-AN 2680
+PT++W ++G LD+K + R + G + + SD+ +Y C N G + A
Sbjct: 199 EPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRK--SDAGKYVCVGTNMVGERESEVAE 255
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRY 2740
L V P+F + + ++ +C RG P+P + W KDD ++P RY
Sbjct: 256 LTVLER-------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRY 307
Query: 2741 QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
+ + D L I T D G+YTC AEN V +++ S + E
Sbjct: 308 E---IRDD-HTLKIRKVTAGDMGSYTCVAENMV-------------GKAEASATLTVQEP 350
Query: 2801 TRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGR-----SVTE 2854
PHF D VA G T+ Q E G P + W REG S
Sbjct: 351 ------------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQP 398
Query: 2855 VYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
++R V Q L +++V ++ G Y C+ + G++ A + V + +P
Sbjct: 399 PQSSSRFSVSQ-TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV--IADRPPP 455
Query: 2915 IVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ + + ++V +S G P P
Sbjct: 456 VIRQGPVNQTVAVDGTFVLSCVATGSPVP 484
Score = 63.7 bits (148), Expect = 1e-08
Identities = 70/265 (26%), Positives = 98/265 (36%), Gaps = 40/265 (15%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-----RRNKYQD 3219
D+PP+ D V P L C+ G P P + WYK GE V DK R
Sbjct: 65 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 124
Query: 3220 EQFHTLEI--APTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D GVY ARN G AVS + L V A + +F +
Sbjct: 125 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV-----AILRDDFRQNPSDV 179
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ +P ++W +DG L I R G +L + DA
Sbjct: 180 MVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGG--KLMITYTRKSDA 235
Query: 3337 GVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA 3395
G Y C +N VG R S ++ V+ + P F+++P +
Sbjct: 236 GKYVCVGTNMVGERESEVAELTVL----------------------ERPSFVKRPSNLAV 273
Query: 3396 REGDTVIIECEVVGDPKPDVYWLRD 3420
D+ +CE GDP P V W +D
Sbjct: 274 TVDDSAEFKCEARGDPVPTVRWRKD 298
Score = 52.8 bits (121), Expect = 2e-05
Identities = 105/478 (21%), Positives = 165/478 (34%), Gaps = 84/478 (17%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL 2634
E S ++E L R S K + +T V+ S + C PTV W ++
Sbjct: 248 ERESEVAELTVLERPSFVKRPSNLAVT----VDDS-AEFKCEARGDPVPTVRWRKD---- 298
Query: 2635 DNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
D +L + + TL++ D Y+C EN G SA L V PP
Sbjct: 299 DGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE-------PP 351
Query: 2695 TFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQ--------IPSDGRYQAFYLA 2746
F RD + +C G P P I W ++ Q S R+
Sbjct: 352 HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG 411
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
D L I N D G Y C+ N V+ +++T +
Sbjct: 412 D----LTITNVQRSDVGYYICQTLN-------------------VAGSIITKAYLEVTDV 448
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARV-FVE 2864
+ P + VA GT L G P + W ++G V+ +++R+ +E
Sbjct: 449 IADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST--QDSRIKQLE 506
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDIL 2924
G+ + + + +T G YTC A + G +A I V
Sbjct: 507 NGVLQIRYAKLGDT--GRYTCIASTPSGEATWSAYIEV---------------------- 542
Query: 2925 ISVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
++ + + P +P P +P V D N V+L+W + P +Y +
Sbjct: 543 ----QEFGVPVQPPRPTDPNLIPS-APSKPEVTDVSRNTVTLSWQPNLNSGATPT-SYII 596
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAF-NLKQGEEYHFRVTPRNRYGWGESSQTSSSI 3041
E++ G+ W + A LK Y F V N YG + SQ S +
Sbjct: 597 EAF--SHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 652
Score = 35.9 bits (79), Expect = 2.6
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS---DGRYQAFYLADG- 2748
PP D L C+ G+P P I W+K +++ + D R L G
Sbjct: 67 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 126
Query: 2749 --VCRLAIDNPTPEDSGTYTCKAEN 2771
R+ + D G Y C A N
Sbjct: 127 LFFLRIVHGRKSRPDEGVYVCVARN 151
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion molecule
CD56 protein.
Length = 848
Score = 85.0 bits (201), Expect = 4e-15
Identities = 85/314 (27%), Positives = 126/314 (40%), Gaps = 39/314 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G++ L C + P P + W K+G ++E+E F+ LTIK ++ +DE Y C
Sbjct: 228 GQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYIC 287
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A N G+ L V + + VE Q M L ++
Sbjct: 288 IAENKAGEQDATIHLKVFA------------KPKITYVEN----QTAMELEEQ------- 324
Query: 3185 VRLTCQVIGSPPPKVSWYKD-----GEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
V LTC+ G P P ++W EE D + +L + D G Y
Sbjct: 325 VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 384
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
TA N G S L V AP+ G +Y EG+++ I+ V AYPS +
Sbjct: 385 CTASNTIGQDSQSMYLEVQ------YAPKLQ-GPVAVYTW-EGNQVNITCEVFAYPSATI 436
Query: 3300 TWYRDGVRLRPSRRA-IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+W+RDG L S + I + L + + D G Y CTA N +G+ S + +
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESF--EFIL 494
Query: 3359 IGTDQTSEPRIPPV 3372
+ D S P I V
Sbjct: 495 VQADTPSSPSIDQV 508
Score = 67.7 bits (158), Expect = 7e-10
Identities = 47/182 (25%), Positives = 76/182 (41%), Gaps = 12/182 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVP 2658
+ + TA G V L C +PT++W ++G ++ + K + D L +
Sbjct: 220 IVNATANLGQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDK 279
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
+D AEY C EN+ G + +LKV+ P T T E ++ L C
Sbjct: 280 NDEAEYICIAENKAGEQDATIHLKVFAK-------PKITYVENQTAMELEEQVTLTCEAS 332
Query: 2719 GQPLPKITWFKDDKQIPSDGR----YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
G P+P ITW + I S+ + + V L + + D+G Y C A N++
Sbjct: 333 GDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 392
Query: 2775 TD 2776
D
Sbjct: 393 QD 394
Score = 58.8 bits (136), Expect = 3e-07
Identities = 83/371 (22%), Positives = 135/371 (36%), Gaps = 57/371 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVP-GVVWMK-NGHEVEEEAGRMTSQFNG-FDCCL 3109
VDI+P Q +I GE+ C V G + W NG ++ R++ +N L
Sbjct: 22 VDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTL 81
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
TI + NIDD G Y C T G S EA +K + + PQ
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSES--------------EATVNVKIFQKLMFKNAPTPQ 127
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D + C V+ S PP + W G +V+ K+ ++ + L+I
Sbjct: 128 EFREGED--------AVIVCDVVSSLPPTIIWKHKGRDVIL-KKDVRFIVLSNNYLQIRG 178
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLYK--LHEGDELR 3286
D G Y R + G + K I+ V P + + + G +
Sbjct: 179 IKKTDEGTYRCEGRILAR------GEINFKDIQVIVNVPPTIRARQNIVNATANLGQSVT 232
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ E +P ++W +DG ++ + D +L + V D Y C A N+
Sbjct: 233 LVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENK 292
Query: 3347 VGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECE 3406
G + ++V ++P+I ++ + E E V + CE
Sbjct: 293 AGEQDATIHLKVF-----AKPKI---------------TYVENQTAMELEE--QVTLTCE 330
Query: 3407 VVGDPKPDVYW 3417
GDP P + W
Sbjct: 331 ASGDPIPSITW 341
Score = 55.2 bits (127), Expect = 4e-06
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 14/193 (7%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLI 2649
+K +F T + EG + C V+SS PT+ W G V+L +++ +V
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRF---IVLSNN 172
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS---IRDTFHL 2706
L++ +D Y C G I + +PPT + T +L
Sbjct: 173 YLQIRGIKKTDEGTYRC-----EGRILARGEINFKDIQVIVNVPPTIRARQNIVNATANL 227
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
++ + L C P P ++W KD +QI + + + +D +L I D Y
Sbjct: 228 GQS-VTLVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 2767 CKAENSVWTDQIT 2779
C AEN T
Sbjct: 287 CIAENKAGEQDAT 299
Score = 52.8 bits (121), Expect = 2e-05
Identities = 48/186 (25%), Positives = 76/186 (40%), Gaps = 21/186 (11%)
Query: 2598 TFLTDRTAVE-GSRVKLTCSVISSSDPTVTWY---RN----GVLLDNKLKYRKKLVDGLI 2649
T++ ++TA+E +V LTC P++TW RN LD + R +
Sbjct: 311 TYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSL 370
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAE 2708
TL+ + +D+ EY CT N G S S L+V Y P+ +
Sbjct: 371 TLKSIQY--TDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---------VYTWEG 419
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQ-AFYLADGVCRLAIDNPTPEDSGTYTC 2767
N++ + C + P I+WF+D + +PS Y L + + D G Y C
Sbjct: 420 NQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNC 479
Query: 2768 KAENSV 2773
A N +
Sbjct: 480 TAVNRI 485
Score = 41.5 bits (93), Expect = 0.052
Identities = 71/337 (21%), Positives = 126/337 (37%), Gaps = 48/337 (14%)
Query: 2615 CSVISSS-DPTVTWYR-NGVLLDNKLKYRKKLV---DGLITLEVLNAVPSDSAEYSCTVE 2669
C V + D ++W+ NG L + R +V D TL + NA D+ Y C V
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPN-QQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVT 99
Query: 2670 NENGAIS-TSANLKVYPS--FEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
E+G+ S + N+K++ F+ +P P F + V+ C + P I
Sbjct: 100 GEDGSESEATVNVKIFQKLMFKNAPTPQEFREG---------EDAVIVCDVVSSLPPTII 150
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W + + + L++ L I D GTY C+ + +NF
Sbjct: 151 WKHKGRDVILKKDVRFIVLSNNY--LQIRGIKKTDEGTYRCEGRILARGE-----INF-- 201
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWL 2846
++ QV +V T ARQ++ + + G + T+ E PT + W
Sbjct: 202 KDIQV---IVNVPPTIRARQNIVNATANLGQSV---------TLVCDAERFPEPT-MSWT 248
Query: 2847 REGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPS 2906
++G + + + + L + V + + Y C A + G D + V
Sbjct: 249 KDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVF--- 305
Query: 2907 DLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP + E + + E + ++ G+P P
Sbjct: 306 ---AKPKITY--VENQTAMELEEQVTLTCEASGDPIP 337
Score = 41.5 bits (93), Expect = 0.052
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD--GLITLEVLNAVPSDSAEY 2664
EG++V +TC V + T++W+R+G LL + K+ + LEV +D Y
Sbjct: 418 EGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNY 477
Query: 2665 SCTVENENG 2673
+CT N G
Sbjct: 478 NCTAVNRIG 486
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 84.2 bits (199), Expect = 7e-15
Identities = 98/366 (26%), Positives = 133/366 (36%), Gaps = 49/366 (13%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V I P QL + G+ A CS G P P + W G++ ++ L +
Sbjct: 1868 VSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGG------PGGQLPAKAQIHGGILRLP 1921
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D+ +Y C A H A AV+ V G P+ +
Sbjct: 1922 AVEPTDQAQYLCRA---HSSAGQQVARAVL------------------HVHGGGGPRVQV 1960
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+V A VRL C+ G P ++W K+G + R + TL I
Sbjct: 1961 SPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSER---TDIATLLIPAITT 2017
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A + +G +VV A P P + EG L ++ VV
Sbjct: 2018 ADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSP--SVTEGQTLDLNCVVA 2075
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
VTWYR G L P + G L L V+ D+G Y C N G
Sbjct: 2076 GSAHAQVTWYRRGGSLPPHTQV------HGS-RLRLPQVSPADSGEYVCRVENGSGPKEA 2128
Query: 3353 SGKVEVI-GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S V V+ GT S P P VP S P+ I +P SS EG T+ + C V G
Sbjct: 2129 SITVSVLHGTH--SGPSYTP------VPGSTRPIRI-EPSSSHVAEGQTLDLNCVVPGQA 2179
Query: 3412 KPDVYW 3417
V W
Sbjct: 2180 HAQVTW 2185
Score = 81.4 bits (192), Expect = 5e-14
Identities = 91/357 (25%), Positives = 151/357 (42%), Gaps = 44/357 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R ++ L+ L ++ P+DS EYSC
Sbjct: 2840 EGQTLDLKCVVPGQAHAQVTWHKRG----GNLPARHQVHGPLLRLNQVS--PADSGEYSC 2893
Query: 2667 TVENENGAISTSANLKVYPSFEASPIP-PTFTRSI---RDTFHLAENE-LVLECRIRGQP 2721
V +G + S + + PS PIP P + I + H+ E + L L C + GQ
Sbjct: 2894 QVTGSSGTLEASVLVTIEPS-SPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQA 2952
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
++TW+K +P+ R+Q +L + +P DSG Y C+A + +Q F
Sbjct: 2953 HAQVTWYKRGGSLPA--RHQTH-----GSQLRLHLVSPADSGEYVCRAASGPGPEQEASF 3005
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V P+ ++ + R S++ P V Q + + + P
Sbjct: 3006 T------VTVPPSEGSSYRLRSPVISID---PPSSTV----QQGQDASFKCLIHDGAAPI 3052
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+EW + E+ N + + T+ + G Y C A +A+G A +
Sbjct: 3053 SLEWKTRNQ---ELEDNVHISPNGSIITIV--GTRPSNHGTYRCVASNAYG-----VAQS 3102
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
VV S + G P V V PE + + VG+ + + + GEP+ A RI P ++
Sbjct: 3103 VVNLS-VHGPPTVSV-LPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLE 3157
Score = 80.2 bits (189), Expect = 1e-13
Identities = 85/321 (26%), Positives = 132/321 (41%), Gaps = 39/321 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T VEG + L C V +TWY+ G L R + + L ++ +DS E
Sbjct: 2640 TVVEGQTLDLNCVVARQPQAIITWYKRG----GSLPSRHQTHGSHLRLHQMSV--ADSGE 2693
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---DTFHLAENE-LVLECRIRG 2719
Y C N A+ S + V PS SP P + IR + H+AE E L L C + G
Sbjct: 2694 YVCRANNNIDALEASIVISVSPS-AGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2752
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
Q ++TW K +PS + + RL + + +P DSG Y C+ S + +
Sbjct: 2753 QAHAQVTWHKRGGSLPSHHQTRG-------SRLRLHHVSPADSGEYVCRVMGSSGPLEAS 2805
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V S I + SR VA G T+ L+ + G
Sbjct: 2806 VLVTIEASGSSAVHVPAPGGAPPIRIEPSSSR------------VAEGQTLDLKCVVPGQ 2853
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G ++ AR V L L L+ V+ +SG Y+C+ + G ++ +
Sbjct: 2854 AHAQVTWHKRGGNLP-----ARHQVHGPL--LRLNQVSPADSGEYSCQVTGSSGTLEASV 2906
Query: 2899 AITVVQPSDLDGKPAVIVGRP 2919
+T ++PS PA + +P
Sbjct: 2907 LVT-IEPSSPGPIPAPGLAQP 2926
Score = 78.2 bits (184), Expect = 5e-13
Identities = 91/356 (25%), Positives = 147/356 (41%), Gaps = 46/356 (12%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTA--VEGSRVKLTCSVISSSDPTVTW 2627
S EA +++ ++ LS + ++ + + +A G + L C V S + T+TW
Sbjct: 2508 SSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITW 2567
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
Y+ G L R ++V L + P+DS EY C V N G+ TS + + S
Sbjct: 2568 YKRG----GSLPSRHQIVGS--RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG 2621
Query: 2688 EA---SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+ S PP S T + L L C + QP ITW+K +PS R+Q
Sbjct: 2622 SSHVPSVSPPIRIESSSPTV-VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RHQTHG 2678
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
L + + DSG Y C+A N++ D + + + S SP+ +
Sbjct: 2679 -----SHLRLHQMSVADSGEYVCRANNNI--DALEASIVISVSPSAGSPSAPGSSMP--- 2728
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFV 2863
+ES H VA G T+ L + G +V W + G S+ ++
Sbjct: 2729 -IRIESSSSH---------VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQT----- 2773
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP 2919
+G L L V+ +SG Y CR + G ++ + +T+ + G AV V P
Sbjct: 2774 -RG-SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI----EASGSSAVHVPAP 2823
Score = 76.2 bits (179), Expect = 2e-12
Identities = 91/358 (25%), Positives = 132/358 (36%), Gaps = 60/358 (16%)
Query: 3065 GETANLTCSVKGK-PVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G C+ K K P +VW + + G++ ++ F+ LTI+++ + D G Y
Sbjct: 1786 GADVTFICTAKSKSPAYTLVWTRLHN------GKLPTRAMDFNGILTIRNVQLSDAGTYV 1839
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C +N A L V T+ SA V +PPQ T VQ
Sbjct: 1840 CTGSNMFAMDQGTATLHVQASGTL-----------SAPVVSIHPPQLT-------VQPGQ 1881
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C GSP P + W G + + + PT D Y A
Sbjct: 1882 LAEFRCSATGSPTPTLEW--TGGPGGQLPAKAQIHGGILRLPAVEPT---DQAQYLCRAH 1936
Query: 3244 NNSGAVSCHCGLVV--DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+++G L V G R V+PE ++H G +R+ PS +TW
Sbjct: 1937 SSAGQQVARAVLHVHGGGGPRVQVSPE-------RTQVHAGRTVRLYCRAAGVPSATITW 1989
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++G L P R+ +R L + A+TT DAG Y C A++ G A +V V+
Sbjct: 1990 RKEGGSLPPQARS----ERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSA 2045
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
S PPV I P EG T+ + C V G V W R
Sbjct: 2046 SDASP---PPVKIESSSP--------------SVTEGQTLDLNCVVAGSAHAQVTWYR 2086
Score = 74.9 bits (176), Expect = 5e-12
Identities = 78/298 (26%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R + L+ L P+DS EY C
Sbjct: 2165 EGQTLDLNCVVPGQAHAQVTWHKRG----GSLPARHQTHGSLLRLH--QVTPADSGEYVC 2218
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKI 2725
V +G + S + + S PIPP S T +AE + L L C + GQ ++
Sbjct: 2219 HVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSST--VAEGQTLDLSCVVAGQAHAQV 2276
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
TW+K +P+ R+Q RL I +P D+G Y C+A N
Sbjct: 2277 TWYKRGGSLPA--RHQV-----RGSRLYIFQASPADAGQYVCRASN-------------- 2315
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVE 2844
G E+ ++ V + +A + S +P + QVA G T+ L + G +V
Sbjct: 2316 GMEASITVTVTGTQGANLAYPA-GSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT 2373
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
W + G S+ ++ G L L + +SG Y CR + ++ + +T+
Sbjct: 2374 WHKRGGSLPVRHQT------HG-SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2424
Score = 69.7 bits (163), Expect = 2e-10
Identities = 90/327 (27%), Positives = 135/327 (41%), Gaps = 56/327 (17%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
LS + P + + EG + L C V S+ VTWYR G L + V
Sbjct: 2043 LSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQ-----V 2097
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASP--IP-PTFTRSIR- 2701
G L + P+DS EY C VEN +G S + V + P P P TR IR
Sbjct: 2098 HG-SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRI 2156
Query: 2702 --DTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPT 2758
+ H+AE + L L C + GQ ++TW K +P+ R+Q L + T
Sbjct: 2157 EPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RHQTH-----GSLLRLHQVT 2209
Query: 2759 PEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
P DSG Y C + + + V E+ V P + + +ES
Sbjct: 2210 PADSGEYVCHVVGTSGPLEASVLVTI---EASVIPGPIPPVR-------IES-------- 2251
Query: 2819 LTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVY--RNARVFVEQGLYTLALSDV 2875
+ VA G T+ L + G +V W + G S+ + R +R+++ Q
Sbjct: 2252 -SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ---------A 2301
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITV 2902
+ ++G Y CRA ++G M A+ITV
Sbjct: 2302 SPADAGQYVCRA--SNG---MEASITV 2323
Score = 68.9 bits (161), Expect = 3e-10
Identities = 82/312 (26%), Positives = 124/312 (39%), Gaps = 41/312 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V S VTW++ G L R + L+ L A P+DS EY C
Sbjct: 2354 EGQTLDLNCVVPGQSHAQVTWHKRG----GSLPVRHQTHGSLLRL--YQASPADSGEYVC 2407
Query: 2667 TVENENGAISTSANLKVYP--SFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP 2723
V + + S + + P S A + PT R + +AE + L L C + GQ
Sbjct: 2408 RVLGSSVPLEASVLVTIEPAGSVPALGVTPT-VRIESSSSQVAEGQTLDLNCLVAGQAHA 2466
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW K +P+ R+Q RL + TP DSG Y C+ S T + + V
Sbjct: 2467 QVTWHKRGGSLPA--RHQVH-----GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVT 2519
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTR 2842
R S S + A RI S +A G T+ L + P
Sbjct: 2520 IQQRLSG-SHSQGVAYPVRIESSSA--------------SLANGHTLDLNCLVASQAPHT 2564
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + G S+ ++ L + VT +SG Y C + G+ + + +T
Sbjct: 2565 ITWYKRGGSLPSRHQIVG-------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVT- 2616
Query: 2903 VQPSDLDGKPAV 2914
+Q S P+V
Sbjct: 2617 IQGSGSSHVPSV 2628
Score = 65.7 bits (153), Expect = 3e-09
Identities = 84/342 (24%), Positives = 134/342 (39%), Gaps = 36/342 (10%)
Query: 2602 DRTAVEGSR-VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+RT V R V+L C T+TW + G L + R + D + TL + +D
Sbjct: 1963 ERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQA--RSERTD-IATLLIPAITTAD 2019
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C + G + V + +ASP PP S + + L L C + G
Sbjct: 2020 AGFYLCVATSPAGTAQARIQVVVLSASDASP-PPVKIESSSPSVTEGQT-LDLNCVVAGS 2077
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
++TW++ +P + RL + +P DSG Y C+ EN + +
Sbjct: 2078 AHAQVTWYRRGGSLPPHTQVHG-------SRLRLPQVSPADSGEYVCRVENGSGPKEASI 2130
Query: 2781 FVN-FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V+ G S S V TR R +E H VA G T+ L + G
Sbjct: 2131 TVSVLHGTHSGPSYTPVPG-STRPIR--IEPSSSH---------VAEGQTLDLNCVVPGQ 2178
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G S+ AR L L L VT +SG Y C G ++ +
Sbjct: 2179 AHAQVTWHKRGGSLP-----ARHQTHGSL--LRLHQVTPADSGEYVCHVVGTSGPLEASV 2231
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
+T ++ S + G P V ++ G+ +++S G+
Sbjct: 2232 LVT-IEASVIPG-PIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2271
Score = 65.3 bits (152), Expect = 4e-09
Identities = 92/374 (24%), Positives = 137/374 (36%), Gaps = 58/374 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V + P + ++ AG T L C G P + W K G + +A + L I
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDI----ATLLIP 2013
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
I D G Y C AT+ G A AR+ VV + +DA PP +
Sbjct: 2014 AITTADAGFYLCVATSPAGTAQ--ARIQVVV---LSASDAS-------------PPPVKI 2055
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L C V GS +V+WY+ G + + + +++P
Sbjct: 2056 ESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPHTQVHGSRLRLPQVSPA-- 2110
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG------LEPLYK-LHEGDEL 3285
D G Y N SG + V G + + G +EP + EG L
Sbjct: 2111 -DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTL 2169
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
++ VV VTW++ G L P+R G + L L VT D+G Y C
Sbjct: 2170 DLNCVVPGQAHAQVTWHKRGGSL-PARH-----QTHGSL-LRLHQVTPADSGEYVC---- 2218
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIEC 3405
V+GT E + + + +P P+ I + SS EG T+ + C
Sbjct: 2219 -----------HVVGTSGPLEASVLVTIEASVIPGPIPPVRI-ESSSSTVAEGQTLDLSC 2266
Query: 3406 EVVGDPKPDVYWLR 3419
V G V W +
Sbjct: 2267 VVAGQAHAQVTWYK 2280
Score = 62.1 bits (144), Expect = 3e-08
Identities = 87/356 (24%), Positives = 128/356 (35%), Gaps = 46/356 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G T +L C V + + W K G G + S+ L I + D G Y C
Sbjct: 2548 GHTLDLNCLVASQAPHTITWYKRG-------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+N G T +VT ++ S+ V PP + V
Sbjct: 2601 HVSNGAGSRETSL---IVT----------IQGSGSSHVPSVSPP-IRIESSSPTVVEGQT 2646
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ L C V P ++WYK G + +++Q H L + ++ D G Y A N
Sbjct: 2647 LDLNCVVARQPQAIITWYKRGGSLP-----SRHQTHGSH-LRLHQMSVADSGEYVCRANN 2700
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRISAVVEAYPSVGVTW 3301
N A+ + V + AP + + EG+ L ++ VV VTW
Sbjct: 2701 NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTW 2760
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++ G L PS G L L V+ D+G Y C G S V I
Sbjct: 2761 HKRGGSL-PSHHQTR-----GS-RLRLHHVSPADSGEYVCRVMGSSGPLEASVLV-TIEA 2812
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+S +P P P+ I +P SS EG T+ ++C V G V W
Sbjct: 2813 SGSSAVHVP-------APGGAPPIRI-EPSSSRVAEGQTLDLKCVVPGQAHAQVTW 2860
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/310 (27%), Positives = 121/310 (39%), Gaps = 51/310 (16%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG + L+C V + VTWY+ G L + + R L + A P+D+ +
Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGS------RLYIFQASPADAGQ 2308
Query: 2664 YSCTVENENGAIST-------SANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLEC 2715
Y C N A T ANL YP+ PI R + +AE + L L C
Sbjct: 2309 YVCRASNGMEASITVTVTGTQGANL-AYPAGSTQPI-----RIEPSSSQVAEGQTLDLNC 2362
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ GQ ++TW K +P R+Q + RL +P DSG Y C+ S +
Sbjct: 2363 VVPGQSHAQVTWHKRGGSLPV--RHQTH---GSLLRLY--QASPADSGEYVCRVLGS--S 2413
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ V T + P + RI S QVA G T+ L
Sbjct: 2414 VPLEASVLVTIEPAGSVPALGVTPTVRIESSS--------------SQVAEGQTLDLNCL 2459
Query: 2836 IRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
+ G +V W + G S+ AR V L L VT +SG Y CR + G
Sbjct: 2460 VAGQAHAQVTWHKRGGSLP-----ARHQVHGS--RLRLLQVTPADSGEYVCRVVGSSGTQ 2512
Query: 2895 DMNAAITVVQ 2904
+ + +T+ Q
Sbjct: 2513 EASVLVTIQQ 2522
Score = 60.9 bits (141), Expect = 8e-08
Identities = 80/364 (21%), Positives = 135/364 (37%), Gaps = 50/364 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ G+T +L C V +P + W K G G + S+ L + +++ D G
Sbjct: 2641 VVEGQTLDLNCVVARQPQAIITWYKRG-------GSLPSRHQTHGSHLRLHQMSVADSGE 2693
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A N ++V S G P + V
Sbjct: 2694 YVCRANNNIDALEASIVISVSPSAG------------SPSAPGSSMP-IRIESSSSHVAE 2740
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + ++ + + ++P D G Y
Sbjct: 2741 GETLDLNCVVPGQAHAQVTWHKRGGSL---PSHHQTRGSRLRLHHVSPA---DSGEYVCR 2794
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY------KLHEGDELRISAVVEAYP 3295
+SG + + ++ + V G P+ ++ EG L + VV
Sbjct: 2795 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQA 2854
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
VTW++ G L P+R + G + L L V+ D+G Y+C + G S
Sbjct: 2855 HAQVTWHKRGGNL-PARHQV-----HGPL-LRLNQVSPADSGEYSCQVTGSSGTLEASVL 2907
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T EP P + +P + +P++I + SS EG T+ + C V G V
Sbjct: 2908 V-------TIEPSSPGPIPAPGLA---QPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQV 2956
Query: 3416 YWLR 3419
W +
Sbjct: 2957 TWYK 2960
Score = 60.5 bits (140), Expect = 1e-07
Identities = 92/366 (25%), Positives = 135/366 (36%), Gaps = 70/366 (19%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L + AG TA L CS G P P + W K + + R+ L I + D
Sbjct: 3220 ELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQH-RLEGD------TLIIPRVAQQD 3272
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y C AT+ G A L V + PP T
Sbjct: 3273 SGQYICNATSPAGHAEATIILHV-----------------------ESPPYATTVPEHAS 3309
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
VQA V+L C G+PP W + G + R ++E H AP +D G Y
Sbjct: 3310 VQAGETVQLQCLAHGTPPLTFQWSRVGSSL---PGRATARNELLHFERAAP---EDSGRY 3363
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR-ISAVVE---AY 3294
N G+ L+V + A G P ++ E + I A VE A
Sbjct: 3364 RCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAV 3423
Query: 3295 PS---VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
PS + W+++G +L P +DG L + + G Y C A G+A
Sbjct: 3424 PSDRGTQLRWFKEGGQLPPGHSV-----QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQ 3476
Query: 3352 TSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S ++ + +P V+I ++ S + + + G V EC +GDP
Sbjct: 3477 ASAQLVI--------QALPSVLI--NIRTSVQTVVV----------GHAVEFECLALGDP 3516
Query: 3412 KPDVYW 3417
KP V W
Sbjct: 3517 KPQVTW 3522
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/372 (22%), Positives = 134/372 (36%), Gaps = 54/372 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P ++ G+T +L C V G+ V W K G G + + L +
Sbjct: 2343 IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG-------GSLPVRHQTHGSLLRLY 2395
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG-DYPPQFT 3171
+ D G Y C V+ EA + E + V P
Sbjct: 2396 QASPADSGEYVCR---------------VLGSSVPLEASVLVTIEPAGSVPALGVTPTVR 2440
Query: 3172 MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
+ +V + L C V G +V+W+K G + R++ + L++ P
Sbjct: 2441 IESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL---PARHQVHGSRLRLLQVTPA- 2496
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRIS 3288
D G Y +SG + + + + + + L G L ++
Sbjct: 2497 --DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLN 2554
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+V + +TWY+ G L PSR I+ G L + VT D+G Y C SN G
Sbjct: 2555 CLVASQAPHTITWYKRGGSL-PSRHQIV-----GS-RLRIPQVTPADSGEYVCHVSNGAG 2607
Query: 3349 RASTSGKVEVIGTDQTSEPRI-PPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
TS V + G+ + P + PP+ I S P + EG T+ + C V
Sbjct: 2608 SRETSLIVTIQGSGSSHVPSVSPPIRIE-----SSSPTVV---------EGQTLDLNCVV 2653
Query: 3408 VGDPKPDVYWLR 3419
P+ + W +
Sbjct: 2654 ARQPQAIITWYK 2665
Score = 58.8 bits (136), Expect = 3e-07
Identities = 75/327 (22%), Positives = 119/327 (36%), Gaps = 40/327 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET +L C V G+ V W K G G + S L + ++ D G
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRG-------GSLPSHHQTRGSRLRLHHVSPADSGE 2790
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C + G + + +A G PP + RV
Sbjct: 2791 YVCRVMGSSGPLEASVLVTI---------EASGSSAVHVPAPGGAPP-IRIEPSSSRVAE 2840
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ +++P D G Y
Sbjct: 2841 GQTLDLKCVVPGQAHAQVTWHKRGGNL---PARHQVHGPLLRLNQVSPA---DSGEYSCQ 2894
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLY------KLHEGDELRISAVVEAY 3294
+SG + + ++ + AP +P+Y + EG L ++ VV
Sbjct: 2895 VTGSSGTLEASVLVTIEPSSPGPIPAPGLA---QPIYIEASSSHVTEGQTLDLNCVVPGQ 2951
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
VTWY+ G L P+R Q+ L L V+ D+G Y C A++ G +
Sbjct: 2952 AHAQVTWYKRGGSL-PARHQT----HGSQLRLHL--VSPADSGEYVCRAASGPGPEQEAS 3004
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ + S R+ VIS D P S
Sbjct: 3005 FTVTVPPSEGSSYRLRSPVISIDPPSS 3031
Score = 57.6 bits (133), Expect = 7e-07
Identities = 87/368 (23%), Positives = 133/368 (36%), Gaps = 43/368 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P V I + G+T +L C V G V W + G + +Q +G L
Sbjct: 2050 PPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPH-----TQVHGSR--L 2102
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ ++ D G Y C N G ++V+ V G P
Sbjct: 2103 RLPQVSPADSGEYVCRVENGSGPKEASITVSVL--------HGTHSGPSYTPVPGSTRP- 2153
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
+ V + L C V G +V+W+K G + R++ ++ P
Sbjct: 2154 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSL---PARHQTHGSLLRLHQVTP 2210
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
D G Y SG + + ++ + P + EG L +S
Sbjct: 2211 A---DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSS-TVAEGQTLDLSC 2266
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTWY+ G L P+R + R ++ + A+ DAG Y C ASN +
Sbjct: 2267 VVAGQAHAQVTWYKRGGSL-PARHQV----RGSRLYIFQASPA--DAGQYVCRASNGMEA 2319
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+ T V V GT Q + P S +P+ I +P SS+ EG T+ + C V G
Sbjct: 2320 SIT---VTVTGT-QGANLAYPAG--------STQPIRI-EPSSSQVAEGQTLDLNCVVPG 2366
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2367 QSHAQVTW 2374
Score = 57.6 bits (133), Expect = 7e-07
Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 54/401 (13%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKILAGETANLTCSVKGKPV 3079
+R N YG +S V L+ P V +LP G + + G+ L C G+P
Sbjct: 3089 YRCVASNAYGVAQSV-------VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPR 3141
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
W + + + T L I D G Y C A N G A +
Sbjct: 3142 SSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3200
Query: 3140 AVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKV 3199
V T A G PQ + V+A + L C GSP P +
Sbjct: 3201 IVDT---------------GAMAPG--APQVQAEEAELTVEAGHTATLRCSATGSPAPTI 3243
Query: 3200 SWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK 3259
W K + + R + TL I D G Y A + +G L V+
Sbjct: 3244 HWSKLRSPLPWQHRL------EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVES 3297
Query: 3260 GIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD 3319
A PE + G+ +++ + P + W R G L P R
Sbjct: 3298 PPYATTVPEHA-------SVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATA---- 3345
Query: 3320 RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVP 3379
R+ + AA D+G Y C +N+VG A ++ V G P + + +P
Sbjct: 3346 RNELLHFERAA--PEDSGRYRCRVTNKVGSAEAFAQLLVQGP--------PGSLPATSIP 3395
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+ G +V C V D + W ++
Sbjct: 3396 AGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKE 3436
Score = 57.6 bits (133), Expect = 7e-07
Identities = 73/313 (23%), Positives = 114/313 (36%), Gaps = 50/313 (15%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF 3105
AG P V + P G + C+V + W K G G++ +
Sbjct: 3396 AGSTPT-VQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEG-------GQLPPGHSVQ 3447
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
D L I++++ +G Y C+A GKA A+L + +V
Sbjct: 3448 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL----------------- 3490
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
+R + V + V C +G P P+V+W K G + R Q +
Sbjct: 3491 ----INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL----RPGIVQSGG--VV 3540
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
IA L D G Y TA N +G H L+V P+ E ++ G
Sbjct: 3541 RIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ------ALPQISMPQE--VRVPAGSAA 3592
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ YP+ ++W + L P R + L L +V +DAG Y CTA+N
Sbjct: 3593 VFPCIASGYPTPDISWSKLDGSLPPDSRLENNM-------LMLPSVRPQDAGTYVCTATN 3645
Query: 3346 EVGRASTSGKVEV 3358
G+ ++V
Sbjct: 3646 RQGKVKAFAHLQV 3658
Score = 56.4 bits (130), Expect = 2e-06
Identities = 74/311 (23%), Positives = 115/311 (36%), Gaps = 42/311 (13%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S T G + CS S PT+ W +L + ++ G++ L
Sbjct: 1866 PVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGP---GGQLPAKAQIHGGILRLPA 1922
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ P+D A+Y C + G A L V+ P R H A + L
Sbjct: 1923 VE--PTDQAQYLCRAHSSAGQQVARAVLHVH----GGGGPRVQVSPERTQVH-AGRTVRL 1975
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
CR G P ITW K+ +P R + + L I T D+G Y C A +
Sbjct: 1976 YCRAAGVPSATITWRKEGGSLPPQARSE----RTDIATLLIPAITTADAGFYLCVATSPA 2031
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
T Q +++ V++A +ES P V G T+ L
Sbjct: 2032 GTAQ-----------ARIQVVVLSASDASPPPVKIESSSP---------SVTEGQTLDLN 2071
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G +V W R G S+ + +V + L L V+ +SG Y CR + G
Sbjct: 2072 CVVAGSAHAQVTWYRRGGSLPP---HTQVHGSR----LRLPQVSPADSGEYVCRVENGSG 2124
Query: 2893 NVDMNAAITVV 2903
+ + ++V+
Sbjct: 2125 PKEASITVSVL 2135
Score = 56.4 bits (130), Expect = 2e-06
Identities = 87/368 (23%), Positives = 138/368 (37%), Gaps = 54/368 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P + G+T +L C V G+ V W K G G + ++ L +
Sbjct: 2154 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRG-------GSLPARHQTHGSLLRLH 2206
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D G Y C T G A + V + +V + G PP +
Sbjct: 2207 QVTPADSGEYVCHVVGTSGPLE--ASVLVTIEASV--------------IPGPIPP-VRI 2249
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L+C V G +V+WYK G + R++ + + + + +P
Sbjct: 2250 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL---PARHQVRGSRLYIFQASPA-- 2304
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIR-AYVAPEFC-CGLEPLY-KLHEGDELRISA 3289
D G Y A N A S + +G AY A +EP ++ EG L ++
Sbjct: 2305 -DAGQYVCRASNGMEA-SITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 2362
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTW++ G L P R G + L L + D+G Y C V
Sbjct: 2363 VVPGQSHAQVTWHKRGGSL-PVRH-----QTHGSL-LRLYQASPADSGEYVC----RVLG 2411
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+S + V+ T + + +P + ++P V SS+ EG T+ + C V G
Sbjct: 2412 SSVPLEASVLVTIEPAGS-VPALGVTPTVRIESS--------SSQVAEGQTLDLNCLVAG 2462
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2463 QAHAQVTW 2470
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 21/184 (11%)
Query: 2594 PVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P ++T + + +V+ G V+L C + T W R G L + R +L L
Sbjct: 3298 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LH 3351
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
A P DS Y C V N+ G+ A L V S A+ IP T +++ T L
Sbjct: 3352 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3411
Query: 2710 EL----VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ C + ++ WFK+ Q+P Q DGV R I N GTY
Sbjct: 3412 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQ-----DGVLR--IQNLDQSCQGTY 3464
Query: 2766 TCKA 2769
C+A
Sbjct: 3465 ICQA 3468
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 17/212 (8%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
R PV S T +G C + + P ++ W L++ + +IT
Sbjct: 3020 RSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPN--GSIIT 3077
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAE 2708
++ PS+ Y C N G + NL V+ P+ P P + +
Sbjct: 3078 --IVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--------VG 3127
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ LEC G+P W + P+ + + L D L I + P D+GTY C
Sbjct: 3128 KAVTLECVSAGEPRSSARWTRISST-PAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3186
Query: 2769 AENSVWTDQ-ITHFVNFTGRESQVSPNVVTAE 2799
A+N++ T Q + TG + +P V E
Sbjct: 3187 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE 3218
Score = 54.8 bits (126), Expect = 5e-06
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 21/169 (12%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+T V G V+ C + P VTW + G L R +V + + + +D+
Sbjct: 3498 QTVVVGHAVEFECLALGDPKPQVTWSKVGGHL------RPGIVQSGGVVRIAHVELADAG 3551
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y CT N G + L V +A P + + +R A + V C G P
Sbjct: 3552 QYRCTATNAAGTTQSHVLLLV----QALP-QISMPQEVRVP---AGSAAVFPCIASGYPT 3603
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
P I+W K D +P D R L + + L + + P+D+GTY C A N
Sbjct: 3604 PDISWSKLDGSLPPDSR-----LENNM--LMLPSVRPQDAGTYVCTATN 3645
Score = 53.6 bits (123), Expect = 1e-05
Identities = 85/358 (23%), Positives = 126/358 (35%), Gaps = 50/358 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G+ V W K G G + ++ L + ++ D G
Sbjct: 2936 VTEGQTLDLNCVVPGQAHAQVTWYKRG-------GSLPARHQTHGSQLRLHLVSPADSGE 2988
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A + G A V TV ++ R RS + D PP T VQ
Sbjct: 2989 YVCRAASGPGPEQE-ASFTV----TVPPSEGSSYRLRSPVISID-PPSST-------VQQ 3035
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
C + G+ P + W +E+ N + + I T + G Y
Sbjct: 3036 GQDASFKCLIHDGAAPISLEWKTRNQEL----EDNVHISPNGSIITIVGTRPSNHGTYRC 3091
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N G L V V PE P++ + G + + V P
Sbjct: 3092 VASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVW-VKVGKAVTLECVSAGEPRSSAR 3145
Query: 3301 WYRDGVRLRPSRRAIMTLD-RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
W R + P++ T D L +++ DAG Y C A N +G A +VEVI
Sbjct: 3146 WTR--ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK--QVEVI 3201
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P P V ++E + EA G T + C G P P ++W
Sbjct: 3202 VDTGAMAPGAPQV-------QAEEAEL-----TVEA--GHTATLRCSATGSPAPTIHW 3245
Score = 53.6 bits (123), Expect = 1e-05
Identities = 74/359 (20%), Positives = 129/359 (35%), Gaps = 45/359 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L CS S PT+ W + L + L ++ +L TL + DS +
Sbjct: 3222 TVEAGHTATLRCSATGSPAPTIHWSK----LRSPLPWQHRLEGD--TLIIPRVAQQDSGQ 3275
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C + G + L V A+ +P + +T L +C G P
Sbjct: 3276 YICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL-------QCLAHGTPPL 3328
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W + +P GR A L + PEDSG Y C+ N V + + +
Sbjct: 3329 TFQWSRVGSSLP--GRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3381
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
G + + A T + + + G ++ A G T++
Sbjct: 3382 VQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG-ASVEFHCAVPSDRG---------TQL 3431
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +EG + + V+ G+ L + ++ ++ G Y C+A G +A + +
Sbjct: 3432 RWFKEGGQLPPGHS-----VQDGV--LRIQNLDQSCQGTYICQAHGPWGKAQASAQLVI- 3483
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPG--EPCVVDGG 2960
P+V++ + VG + G+PKP+ ++ G P +V G
Sbjct: 3484 -----QALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG 3537
Score = 47.2 bits (107), Expect = 0.001
Identities = 47/185 (25%), Positives = 69/185 (37%), Gaps = 18/185 (9%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L CQV GSPP W ++ V + ++Q + H + P+ D GVY T RN
Sbjct: 1696 LRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPS---DAGVYICTCRNLH 1752
Query: 3247 GAVSCHCGLVV----DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+ + L+V K I V + + P D I P+ + W
Sbjct: 1753 QSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP-----GADVTFICTAKSKSPAYTLVW- 1806
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
RL + +D +G L + V DAG Y CT SN + + V +
Sbjct: 1807 ---TRLHNGKLPTRAMDFNG--ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASG 1861
Query: 3363 QTSEP 3367
S P
Sbjct: 1862 TLSAP 1866
Score = 47.2 bits (107), Expect = 0.001
Identities = 75/360 (20%), Positives = 128/360 (35%), Gaps = 35/360 (9%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SS++ V G P + I P ++ G+T +L C V G+ V W K G G
Sbjct: 2815 SSAVHVPAPGGAPP-IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRG-------GN 2866
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ ++ L + ++ D G YSC+ T G + T +VT +
Sbjct: 2867 LPARHQVHGPLLRLNQVSPADSGEYSCQVT---GSSGTLEASVLVT--------IEPSSP 2915
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
G P + + V + L C V G +V+WYK G + R++
Sbjct: 2916 GPIPAPGLAQPIY-IEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL---PARHQT 2971
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSG---AVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
Q ++P D G Y A + G S + +G +
Sbjct: 2972 HGSQLRLHLVSPA---DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDP 3028
Query: 3275 PLYKLHEGDELRISAVV-EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
P + +G + ++ + + + W L + + + +G I + +
Sbjct: 3029 PSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VHISPNGSI-ITIVGTRP 3083
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
+ G Y C ASN G A + + V G S PV + + E + +PRSS
Sbjct: 3084 SNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSS 3143
Score = 46.0 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+T TC G P P + W N + R+T G L I+D+ D+G Y+C
Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHP-RVTVTSEGGRGTLIIRDVKESDQGAYTC 479
Query: 3125 EATNTHG 3131
EA N G
Sbjct: 480 EAMNARG 486
Score = 41.9 bits (94), Expect = 0.039
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 18/170 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ V+ C+V S + W++ G +L + DG++ ++ L+ S Y C
Sbjct: 3414 GASVEFHCAVPSDRGTQLRWFKEG----GQLPPGHSVQDGVLRIQNLDQ--SCQGTYICQ 3467
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
G SA L + +A P R+ T + + + EC G P P++TW
Sbjct: 3468 AHGPWGKAQASAQLVI----QALPSVLINIRTSVQTV-VVGHAVEFECLALGDPKPQVTW 3522
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K + G Q+ GV R+A + D+G Y C A N+ T Q
Sbjct: 3523 SKVGGHL-RPGIVQS----GGVVRIA--HVELADAGQYRCTATNAAGTTQ 3565
Score = 39.9 bits (89), Expect = 0.16
Identities = 53/234 (22%), Positives = 78/234 (33%), Gaps = 40/234 (17%)
Query: 3031 WGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
WG++ ++ + L ++I ++ G C G P P V W K G
Sbjct: 3472 WGKAQASAQLVIQALPS---VLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH 3528
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
+ Q G + I + + D G+Y C ATN G ++ L V
Sbjct: 3529 LRPGI----VQSGGV---VRIAHVELADAGQYRCTATNAAGTTQSHVLLLV--------- 3572
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
PQ +M ++ RV A C G P P +SW K +
Sbjct: 3573 --------------QALPQISMP-QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPP 3617
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
D R + L + D G Y TA N G V L V + + Y
Sbjct: 3618 DSRLEN------NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPY 3665
Score = 38.3 bits (85), Expect = 0.48
Identities = 24/72 (33%), Positives = 32/72 (44%)
Query: 2823 QVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
Q +RG T+ G PT + R + V E G TL + DV E++ G
Sbjct: 417 QASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGA 476
Query: 2883 YTCRAWSAHGNV 2894
YTC A +A G V
Sbjct: 477 YTCEAMNARGMV 488
Score = 34.7 bits (76), Expect = 5.9
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 10/105 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
GS C P ++W + LD L +L + ++ L + P D+ Y CT
Sbjct: 3589 GSAAVFPCIASGYPTPDISWSK----LDGSLPPDSRLENNMLMLPSVR--PQDAGTYVCT 3642
Query: 2668 VENENGAISTSANL----KVYPSFEASPIPPTFTRSIRDTFHLAE 2708
N G + A+L +V P F +P +I+D + E
Sbjct: 3643 ATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFE 3687
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 84.2 bits (199), Expect = 7e-15
Identities = 98/366 (26%), Positives = 133/366 (36%), Gaps = 49/366 (13%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V I P QL + G+ A CS G P P + W G++ ++ L +
Sbjct: 1868 VSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGG------PGGQLPAKAQIHGGILRLP 1921
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D+ +Y C A H A AV+ V G P+ +
Sbjct: 1922 AVEPTDQAQYLCRA---HSSAGQQVARAVL------------------HVHGGGGPRVQV 1960
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+V A VRL C+ G P ++W K+G + R + TL I
Sbjct: 1961 SPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSER---TDIATLLIPAITT 2017
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A + +G +VV A P P + EG L ++ VV
Sbjct: 2018 ADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSP--SVTEGQTLDLNCVVA 2075
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
VTWYR G L P + G L L V+ D+G Y C N G
Sbjct: 2076 GSAHAQVTWYRRGGSLPPHTQV------HGS-RLRLPQVSPADSGEYVCRVENGSGPKEA 2128
Query: 3353 SGKVEVI-GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S V V+ GT S P P VP S P+ I +P SS EG T+ + C V G
Sbjct: 2129 SITVSVLHGTH--SGPSYTP------VPGSTRPIRI-EPSSSHVAEGQTLDLNCVVPGQA 2179
Query: 3412 KPDVYW 3417
V W
Sbjct: 2180 HAQVTW 2185
Score = 81.4 bits (192), Expect = 5e-14
Identities = 91/357 (25%), Positives = 151/357 (42%), Gaps = 44/357 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R ++ L+ L ++ P+DS EYSC
Sbjct: 2840 EGQTLDLKCVVPGQAHAQVTWHKRG----GNLPARHQVHGPLLRLNQVS--PADSGEYSC 2893
Query: 2667 TVENENGAISTSANLKVYPSFEASPIP-PTFTRSI---RDTFHLAENE-LVLECRIRGQP 2721
V +G + S + + PS PIP P + I + H+ E + L L C + GQ
Sbjct: 2894 QVTGSSGTLEASVLVTIEPS-SPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQA 2952
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
++TW+K +P+ R+Q +L + +P DSG Y C+A + +Q F
Sbjct: 2953 HAQVTWYKRGGSLPA--RHQTH-----GSQLRLHLVSPADSGEYVCRAASGPGPEQEASF 3005
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V P+ ++ + R S++ P V Q + + + P
Sbjct: 3006 T------VTVPPSEGSSYRLRSPVISID---PPSSTV----QQGQDASFKCLIHDGAAPI 3052
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+EW + E+ N + + T+ + G Y C A +A+G A +
Sbjct: 3053 SLEWKTRNQ---ELEDNVHISPNGSIITIV--GTRPSNHGTYRCVASNAYG-----VAQS 3102
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
VV S + G P V V PE + + VG+ + + + GEP+ A RI P ++
Sbjct: 3103 VVNLS-VHGPPTVSV-LPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLE 3157
Score = 80.2 bits (189), Expect = 1e-13
Identities = 85/321 (26%), Positives = 132/321 (41%), Gaps = 39/321 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T VEG + L C V +TWY+ G L R + + L ++ +DS E
Sbjct: 2640 TVVEGQTLDLNCVVARQPQAIITWYKRG----GSLPSRHQTHGSHLRLHQMSV--ADSGE 2693
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---DTFHLAENE-LVLECRIRG 2719
Y C N A+ S + V PS SP P + IR + H+AE E L L C + G
Sbjct: 2694 YVCRANNNIDALEASIVISVSPS-AGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2752
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
Q ++TW K +PS + + RL + + +P DSG Y C+ S + +
Sbjct: 2753 QAHAQVTWHKRGGSLPSHHQTRG-------SRLRLHHVSPADSGEYVCRVMGSSGPLEAS 2805
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V S I + SR VA G T+ L+ + G
Sbjct: 2806 VLVTIEASGSSAVHVPAPGGAPPIRIEPSSSR------------VAEGQTLDLKCVVPGQ 2853
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G ++ AR V L L L+ V+ +SG Y+C+ + G ++ +
Sbjct: 2854 AHAQVTWHKRGGNLP-----ARHQVHGPL--LRLNQVSPADSGEYSCQVTGSSGTLEASV 2906
Query: 2899 AITVVQPSDLDGKPAVIVGRP 2919
+T ++PS PA + +P
Sbjct: 2907 LVT-IEPSSPGPIPAPGLAQP 2926
Score = 78.2 bits (184), Expect = 5e-13
Identities = 91/356 (25%), Positives = 147/356 (41%), Gaps = 46/356 (12%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTA--VEGSRVKLTCSVISSSDPTVTW 2627
S EA +++ ++ LS + ++ + + +A G + L C V S + T+TW
Sbjct: 2508 SSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITW 2567
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
Y+ G L R ++V L + P+DS EY C V N G+ TS + + S
Sbjct: 2568 YKRG----GSLPSRHQIVGS--RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG 2621
Query: 2688 EA---SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+ S PP S T + L L C + QP ITW+K +PS R+Q
Sbjct: 2622 SSHVPSVSPPIRIESSSPTV-VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RHQTHG 2678
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
L + + DSG Y C+A N++ D + + + S SP+ +
Sbjct: 2679 -----SHLRLHQMSVADSGEYVCRANNNI--DALEASIVISVSPSAGSPSAPGSSMP--- 2728
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFV 2863
+ES H VA G T+ L + G +V W + G S+ ++
Sbjct: 2729 -IRIESSSSH---------VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQT----- 2773
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP 2919
+G L L V+ +SG Y CR + G ++ + +T+ + G AV V P
Sbjct: 2774 -RG-SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI----EASGSSAVHVPAP 2823
Score = 76.2 bits (179), Expect = 2e-12
Identities = 91/358 (25%), Positives = 132/358 (36%), Gaps = 60/358 (16%)
Query: 3065 GETANLTCSVKGK-PVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G C+ K K P +VW + + G++ ++ F+ LTI+++ + D G Y
Sbjct: 1786 GADVTFICTAKSKSPAYTLVWTRLHN------GKLPTRAMDFNGILTIRNVQLSDAGTYV 1839
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C +N A L V T+ SA V +PPQ T VQ
Sbjct: 1840 CTGSNMFAMDQGTATLHVQASGTL-----------SAPVVSIHPPQLT-------VQPGQ 1881
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C GSP P + W G + + + PT D Y A
Sbjct: 1882 LAEFRCSATGSPTPTLEW--TGGPGGQLPAKAQIHGGILRLPAVEPT---DQAQYLCRAH 1936
Query: 3244 NNSGAVSCHCGLVV--DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+++G L V G R V+PE ++H G +R+ PS +TW
Sbjct: 1937 SSAGQQVARAVLHVHGGGGPRVQVSPE-------RTQVHAGRTVRLYCRAAGVPSATITW 1989
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++G L P R+ +R L + A+TT DAG Y C A++ G A +V V+
Sbjct: 1990 RKEGGSLPPQARS----ERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSA 2045
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
S PPV I P EG T+ + C V G V W R
Sbjct: 2046 SDASP---PPVKIESSSP--------------SVTEGQTLDLNCVVAGSAHAQVTWYR 2086
Score = 74.9 bits (176), Expect = 5e-12
Identities = 78/298 (26%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R + L+ L P+DS EY C
Sbjct: 2165 EGQTLDLNCVVPGQAHAQVTWHKRG----GSLPARHQTHGSLLRLH--QVTPADSGEYVC 2218
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKI 2725
V +G + S + + S PIPP S T +AE + L L C + GQ ++
Sbjct: 2219 HVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSST--VAEGQTLDLSCVVAGQAHAQV 2276
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
TW+K +P+ R+Q RL I +P D+G Y C+A N
Sbjct: 2277 TWYKRGGSLPA--RHQV-----RGSRLYIFQASPADAGQYVCRASN-------------- 2315
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVE 2844
G E+ ++ V + +A + S +P + QVA G T+ L + G +V
Sbjct: 2316 GMEASITVTVTGTQGANLAYPA-GSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT 2373
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
W + G S+ ++ G L L + +SG Y CR + ++ + +T+
Sbjct: 2374 WHKRGGSLPVRHQT------HG-SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2424
Score = 69.7 bits (163), Expect = 2e-10
Identities = 90/327 (27%), Positives = 135/327 (41%), Gaps = 56/327 (17%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
LS + P + + EG + L C V S+ VTWYR G L + V
Sbjct: 2043 LSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQ-----V 2097
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASP--IP-PTFTRSIR- 2701
G L + P+DS EY C VEN +G S + V + P P P TR IR
Sbjct: 2098 HG-SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRI 2156
Query: 2702 --DTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPT 2758
+ H+AE + L L C + GQ ++TW K +P+ R+Q L + T
Sbjct: 2157 EPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RHQTH-----GSLLRLHQVT 2209
Query: 2759 PEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
P DSG Y C + + + V E+ V P + + +ES
Sbjct: 2210 PADSGEYVCHVVGTSGPLEASVLVTI---EASVIPGPIPPVR-------IES-------- 2251
Query: 2819 LTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVY--RNARVFVEQGLYTLALSDV 2875
+ VA G T+ L + G +V W + G S+ + R +R+++ Q
Sbjct: 2252 -SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ---------A 2301
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITV 2902
+ ++G Y CRA ++G M A+ITV
Sbjct: 2302 SPADAGQYVCRA--SNG---MEASITV 2323
Score = 68.9 bits (161), Expect = 3e-10
Identities = 82/312 (26%), Positives = 124/312 (39%), Gaps = 41/312 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V S VTW++ G L R + L+ L A P+DS EY C
Sbjct: 2354 EGQTLDLNCVVPGQSHAQVTWHKRG----GSLPVRHQTHGSLLRL--YQASPADSGEYVC 2407
Query: 2667 TVENENGAISTSANLKVYP--SFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP 2723
V + + S + + P S A + PT R + +AE + L L C + GQ
Sbjct: 2408 RVLGSSVPLEASVLVTIEPAGSVPALGVTPT-VRIESSSSQVAEGQTLDLNCLVAGQAHA 2466
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW K +P+ R+Q RL + TP DSG Y C+ S T + + V
Sbjct: 2467 QVTWHKRGGSLPA--RHQVH-----GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVT 2519
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTR 2842
R S S + A RI S +A G T+ L + P
Sbjct: 2520 IQQRLSG-SHSQGVAYPVRIESSSA--------------SLANGHTLDLNCLVASQAPHT 2564
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + G S+ ++ L + VT +SG Y C + G+ + + +T
Sbjct: 2565 ITWYKRGGSLPSRHQIVG-------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVT- 2616
Query: 2903 VQPSDLDGKPAV 2914
+Q S P+V
Sbjct: 2617 IQGSGSSHVPSV 2628
Score = 65.7 bits (153), Expect = 3e-09
Identities = 84/342 (24%), Positives = 134/342 (39%), Gaps = 36/342 (10%)
Query: 2602 DRTAVEGSR-VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+RT V R V+L C T+TW + G L + R + D + TL + +D
Sbjct: 1963 ERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQA--RSERTD-IATLLIPAITTAD 2019
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C + G + V + +ASP PP S + + L L C + G
Sbjct: 2020 AGFYLCVATSPAGTAQARIQVVVLSASDASP-PPVKIESSSPSVTEGQT-LDLNCVVAGS 2077
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
++TW++ +P + RL + +P DSG Y C+ EN + +
Sbjct: 2078 AHAQVTWYRRGGSLPPHTQVHG-------SRLRLPQVSPADSGEYVCRVENGSGPKEASI 2130
Query: 2781 FVN-FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V+ G S S V TR R +E H VA G T+ L + G
Sbjct: 2131 TVSVLHGTHSGPSYTPVPG-STRPIR--IEPSSSH---------VAEGQTLDLNCVVPGQ 2178
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G S+ AR L L L VT +SG Y C G ++ +
Sbjct: 2179 AHAQVTWHKRGGSLP-----ARHQTHGSL--LRLHQVTPADSGEYVCHVVGTSGPLEASV 2231
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
+T ++ S + G P V ++ G+ +++S G+
Sbjct: 2232 LVT-IEASVIPG-PIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2271
Score = 65.3 bits (152), Expect = 4e-09
Identities = 92/374 (24%), Positives = 137/374 (36%), Gaps = 58/374 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V + P + ++ AG T L C G P + W K G + +A + L I
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDI----ATLLIP 2013
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
I D G Y C AT+ G A AR+ VV + +DA PP +
Sbjct: 2014 AITTADAGFYLCVATSPAGTAQ--ARIQVVV---LSASDAS-------------PPPVKI 2055
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L C V GS +V+WY+ G + + + +++P
Sbjct: 2056 ESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPHTQVHGSRLRLPQVSPA-- 2110
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG------LEPLYK-LHEGDEL 3285
D G Y N SG + V G + + G +EP + EG L
Sbjct: 2111 -DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTL 2169
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
++ VV VTW++ G L P+R G + L L VT D+G Y C
Sbjct: 2170 DLNCVVPGQAHAQVTWHKRGGSL-PARH-----QTHGSL-LRLHQVTPADSGEYVC---- 2218
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIEC 3405
V+GT E + + + +P P+ I + SS EG T+ + C
Sbjct: 2219 -----------HVVGTSGPLEASVLVTIEASVIPGPIPPVRI-ESSSSTVAEGQTLDLSC 2266
Query: 3406 EVVGDPKPDVYWLR 3419
V G V W +
Sbjct: 2267 VVAGQAHAQVTWYK 2280
Score = 62.1 bits (144), Expect = 3e-08
Identities = 87/356 (24%), Positives = 128/356 (35%), Gaps = 46/356 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G T +L C V + + W K G G + S+ L I + D G Y C
Sbjct: 2548 GHTLDLNCLVASQAPHTITWYKRG-------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+N G T +VT ++ S+ V PP + V
Sbjct: 2601 HVSNGAGSRETSL---IVT----------IQGSGSSHVPSVSPP-IRIESSSPTVVEGQT 2646
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ L C V P ++WYK G + +++Q H L + ++ D G Y A N
Sbjct: 2647 LDLNCVVARQPQAIITWYKRGGSLP-----SRHQTHGSH-LRLHQMSVADSGEYVCRANN 2700
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRISAVVEAYPSVGVTW 3301
N A+ + V + AP + + EG+ L ++ VV VTW
Sbjct: 2701 NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTW 2760
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++ G L PS G L L V+ D+G Y C G S V I
Sbjct: 2761 HKRGGSL-PSHHQTR-----GS-RLRLHHVSPADSGEYVCRVMGSSGPLEASVLV-TIEA 2812
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+S +P P P+ I +P SS EG T+ ++C V G V W
Sbjct: 2813 SGSSAVHVP-------APGGAPPIRI-EPSSSRVAEGQTLDLKCVVPGQAHAQVTW 2860
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/310 (27%), Positives = 121/310 (39%), Gaps = 51/310 (16%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG + L+C V + VTWY+ G L + + R L + A P+D+ +
Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGS------RLYIFQASPADAGQ 2308
Query: 2664 YSCTVENENGAIST-------SANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLEC 2715
Y C N A T ANL YP+ PI R + +AE + L L C
Sbjct: 2309 YVCRASNGMEASITVTVTGTQGANL-AYPAGSTQPI-----RIEPSSSQVAEGQTLDLNC 2362
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ GQ ++TW K +P R+Q + RL +P DSG Y C+ S +
Sbjct: 2363 VVPGQSHAQVTWHKRGGSLPV--RHQTH---GSLLRLY--QASPADSGEYVCRVLGS--S 2413
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ V T + P + RI S QVA G T+ L
Sbjct: 2414 VPLEASVLVTIEPAGSVPALGVTPTVRIESSS--------------SQVAEGQTLDLNCL 2459
Query: 2836 IRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
+ G +V W + G S+ AR V L L VT +SG Y CR + G
Sbjct: 2460 VAGQAHAQVTWHKRGGSLP-----ARHQVHGS--RLRLLQVTPADSGEYVCRVVGSSGTQ 2512
Query: 2895 DMNAAITVVQ 2904
+ + +T+ Q
Sbjct: 2513 EASVLVTIQQ 2522
Score = 60.9 bits (141), Expect = 8e-08
Identities = 80/364 (21%), Positives = 135/364 (37%), Gaps = 50/364 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ G+T +L C V +P + W K G G + S+ L + +++ D G
Sbjct: 2641 VVEGQTLDLNCVVARQPQAIITWYKRG-------GSLPSRHQTHGSHLRLHQMSVADSGE 2693
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A N ++V S G P + V
Sbjct: 2694 YVCRANNNIDALEASIVISVSPSAG------------SPSAPGSSMP-IRIESSSSHVAE 2740
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + ++ + + ++P D G Y
Sbjct: 2741 GETLDLNCVVPGQAHAQVTWHKRGGSL---PSHHQTRGSRLRLHHVSPA---DSGEYVCR 2794
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY------KLHEGDELRISAVVEAYP 3295
+SG + + ++ + V G P+ ++ EG L + VV
Sbjct: 2795 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQA 2854
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
VTW++ G L P+R + G + L L V+ D+G Y+C + G S
Sbjct: 2855 HAQVTWHKRGGNL-PARHQV-----HGPL-LRLNQVSPADSGEYSCQVTGSSGTLEASVL 2907
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T EP P + +P + +P++I + SS EG T+ + C V G V
Sbjct: 2908 V-------TIEPSSPGPIPAPGLA---QPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQV 2956
Query: 3416 YWLR 3419
W +
Sbjct: 2957 TWYK 2960
Score = 60.5 bits (140), Expect = 1e-07
Identities = 92/366 (25%), Positives = 135/366 (36%), Gaps = 70/366 (19%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L + AG TA L CS G P P + W K + + R+ L I + D
Sbjct: 3220 ELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQH-RLEGD------TLIIPRVAQQD 3272
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y C AT+ G A L V + PP T
Sbjct: 3273 SGQYICNATSPAGHAEATIILHV-----------------------ESPPYATTVPEHAS 3309
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
VQA V+L C G+PP W + G + R ++E H AP +D G Y
Sbjct: 3310 VQAGETVQLQCLAHGTPPLTFQWSRVGSSL---PGRATARNELLHFERAAP---EDSGRY 3363
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR-ISAVVE---AY 3294
N G+ L+V + A G P ++ E + I A VE A
Sbjct: 3364 RCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAV 3423
Query: 3295 PS---VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
PS + W+++G +L P +DG L + + G Y C A G+A
Sbjct: 3424 PSDRGTQLRWFKEGGQLPPGHSV-----QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQ 3476
Query: 3352 TSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S ++ + +P V+I ++ S + + + G V EC +GDP
Sbjct: 3477 ASAQLVI--------QALPSVLI--NIRTSVQTVVV----------GHAVEFECLALGDP 3516
Query: 3412 KPDVYW 3417
KP V W
Sbjct: 3517 KPQVTW 3522
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/372 (22%), Positives = 134/372 (36%), Gaps = 54/372 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P ++ G+T +L C V G+ V W K G G + + L +
Sbjct: 2343 IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG-------GSLPVRHQTHGSLLRLY 2395
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG-DYPPQFT 3171
+ D G Y C V+ EA + E + V P
Sbjct: 2396 QASPADSGEYVCR---------------VLGSSVPLEASVLVTIEPAGSVPALGVTPTVR 2440
Query: 3172 MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
+ +V + L C V G +V+W+K G + R++ + L++ P
Sbjct: 2441 IESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL---PARHQVHGSRLRLLQVTPA- 2496
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRIS 3288
D G Y +SG + + + + + + L G L ++
Sbjct: 2497 --DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLN 2554
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+V + +TWY+ G L PSR I+ G L + VT D+G Y C SN G
Sbjct: 2555 CLVASQAPHTITWYKRGGSL-PSRHQIV-----GS-RLRIPQVTPADSGEYVCHVSNGAG 2607
Query: 3349 RASTSGKVEVIGTDQTSEPRI-PPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
TS V + G+ + P + PP+ I S P + EG T+ + C V
Sbjct: 2608 SRETSLIVTIQGSGSSHVPSVSPPIRIE-----SSSPTVV---------EGQTLDLNCVV 2653
Query: 3408 VGDPKPDVYWLR 3419
P+ + W +
Sbjct: 2654 ARQPQAIITWYK 2665
Score = 58.8 bits (136), Expect = 3e-07
Identities = 75/327 (22%), Positives = 119/327 (36%), Gaps = 40/327 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET +L C V G+ V W K G G + S L + ++ D G
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRG-------GSLPSHHQTRGSRLRLHHVSPADSGE 2790
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C + G + + +A G PP + RV
Sbjct: 2791 YVCRVMGSSGPLEASVLVTI---------EASGSSAVHVPAPGGAPP-IRIEPSSSRVAE 2840
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ +++P D G Y
Sbjct: 2841 GQTLDLKCVVPGQAHAQVTWHKRGGNL---PARHQVHGPLLRLNQVSPA---DSGEYSCQ 2894
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLY------KLHEGDELRISAVVEAY 3294
+SG + + ++ + AP +P+Y + EG L ++ VV
Sbjct: 2895 VTGSSGTLEASVLVTIEPSSPGPIPAPGLA---QPIYIEASSSHVTEGQTLDLNCVVPGQ 2951
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
VTWY+ G L P+R Q+ L L V+ D+G Y C A++ G +
Sbjct: 2952 AHAQVTWYKRGGSL-PARHQT----HGSQLRLHL--VSPADSGEYVCRAASGPGPEQEAS 3004
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ + S R+ VIS D P S
Sbjct: 3005 FTVTVPPSEGSSYRLRSPVISIDPPSS 3031
Score = 57.6 bits (133), Expect = 7e-07
Identities = 87/368 (23%), Positives = 133/368 (36%), Gaps = 43/368 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P V I + G+T +L C V G V W + G + +Q +G L
Sbjct: 2050 PPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPH-----TQVHGSR--L 2102
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ ++ D G Y C N G ++V+ V G P
Sbjct: 2103 RLPQVSPADSGEYVCRVENGSGPKEASITVSVL--------HGTHSGPSYTPVPGSTRP- 2153
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
+ V + L C V G +V+W+K G + R++ ++ P
Sbjct: 2154 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSL---PARHQTHGSLLRLHQVTP 2210
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
D G Y SG + + ++ + P + EG L +S
Sbjct: 2211 A---DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSS-TVAEGQTLDLSC 2266
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTWY+ G L P+R + R ++ + A+ DAG Y C ASN +
Sbjct: 2267 VVAGQAHAQVTWYKRGGSL-PARHQV----RGSRLYIFQASPA--DAGQYVCRASNGMEA 2319
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+ T V V GT Q + P S +P+ I +P SS+ EG T+ + C V G
Sbjct: 2320 SIT---VTVTGT-QGANLAYPAG--------STQPIRI-EPSSSQVAEGQTLDLNCVVPG 2366
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2367 QSHAQVTW 2374
Score = 57.6 bits (133), Expect = 7e-07
Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 54/401 (13%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKILAGETANLTCSVKGKPV 3079
+R N YG +S V L+ P V +LP G + + G+ L C G+P
Sbjct: 3089 YRCVASNAYGVAQSV-------VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPR 3141
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
W + + + T L I D G Y C A N G A +
Sbjct: 3142 SSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3200
Query: 3140 AVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKV 3199
V T A G PQ + V+A + L C GSP P +
Sbjct: 3201 IVDT---------------GAMAPG--APQVQAEEAELTVEAGHTATLRCSATGSPAPTI 3243
Query: 3200 SWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK 3259
W K + + R + TL I D G Y A + +G L V+
Sbjct: 3244 HWSKLRSPLPWQHRL------EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVES 3297
Query: 3260 GIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD 3319
A PE + G+ +++ + P + W R G L P R
Sbjct: 3298 PPYATTVPEHA-------SVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATA---- 3345
Query: 3320 RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVP 3379
R+ + AA D+G Y C +N+VG A ++ V G P + + +P
Sbjct: 3346 RNELLHFERAA--PEDSGRYRCRVTNKVGSAEAFAQLLVQGP--------PGSLPATSIP 3395
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+ G +V C V D + W ++
Sbjct: 3396 AGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKE 3436
Score = 57.6 bits (133), Expect = 7e-07
Identities = 73/313 (23%), Positives = 114/313 (36%), Gaps = 50/313 (15%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF 3105
AG P V + P G + C+V + W K G G++ +
Sbjct: 3396 AGSTPT-VQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEG-------GQLPPGHSVQ 3447
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
D L I++++ +G Y C+A GKA A+L + +V
Sbjct: 3448 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL----------------- 3490
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
+R + V + V C +G P P+V+W K G + R Q +
Sbjct: 3491 ----INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL----RPGIVQSGG--VV 3540
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
IA L D G Y TA N +G H L+V P+ E ++ G
Sbjct: 3541 RIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ------ALPQISMPQE--VRVPAGSAA 3592
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ YP+ ++W + L P R + L L +V +DAG Y CTA+N
Sbjct: 3593 VFPCIASGYPTPDISWSKLDGSLPPDSRLENNM-------LMLPSVRPQDAGTYVCTATN 3645
Query: 3346 EVGRASTSGKVEV 3358
G+ ++V
Sbjct: 3646 RQGKVKAFAHLQV 3658
Score = 56.4 bits (130), Expect = 2e-06
Identities = 74/311 (23%), Positives = 115/311 (36%), Gaps = 42/311 (13%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S T G + CS S PT+ W +L + ++ G++ L
Sbjct: 1866 PVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGP---GGQLPAKAQIHGGILRLPA 1922
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ P+D A+Y C + G A L V+ P R H A + L
Sbjct: 1923 VE--PTDQAQYLCRAHSSAGQQVARAVLHVH----GGGGPRVQVSPERTQVH-AGRTVRL 1975
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
CR G P ITW K+ +P R + + L I T D+G Y C A +
Sbjct: 1976 YCRAAGVPSATITWRKEGGSLPPQARSE----RTDIATLLIPAITTADAGFYLCVATSPA 2031
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
T Q +++ V++A +ES P V G T+ L
Sbjct: 2032 GTAQ-----------ARIQVVVLSASDASPPPVKIESSSP---------SVTEGQTLDLN 2071
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G +V W R G S+ + +V + L L V+ +SG Y CR + G
Sbjct: 2072 CVVAGSAHAQVTWYRRGGSLPP---HTQVHGSR----LRLPQVSPADSGEYVCRVENGSG 2124
Query: 2893 NVDMNAAITVV 2903
+ + ++V+
Sbjct: 2125 PKEASITVSVL 2135
Score = 56.4 bits (130), Expect = 2e-06
Identities = 87/368 (23%), Positives = 138/368 (37%), Gaps = 54/368 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P + G+T +L C V G+ V W K G G + ++ L +
Sbjct: 2154 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRG-------GSLPARHQTHGSLLRLH 2206
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D G Y C T G A + V + +V + G PP +
Sbjct: 2207 QVTPADSGEYVCHVVGTSGPLE--ASVLVTIEASV--------------IPGPIPP-VRI 2249
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L+C V G +V+WYK G + R++ + + + + +P
Sbjct: 2250 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL---PARHQVRGSRLYIFQASPA-- 2304
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIR-AYVAPEFC-CGLEPLY-KLHEGDELRISA 3289
D G Y A N A S + +G AY A +EP ++ EG L ++
Sbjct: 2305 -DAGQYVCRASNGMEA-SITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 2362
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTW++ G L P R G + L L + D+G Y C V
Sbjct: 2363 VVPGQSHAQVTWHKRGGSL-PVRH-----QTHGSL-LRLYQASPADSGEYVC----RVLG 2411
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+S + V+ T + + +P + ++P V SS+ EG T+ + C V G
Sbjct: 2412 SSVPLEASVLVTIEPAGS-VPALGVTPTVRIESS--------SSQVAEGQTLDLNCLVAG 2462
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2463 QAHAQVTW 2470
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 21/184 (11%)
Query: 2594 PVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P ++T + + +V+ G V+L C + T W R G L + R +L L
Sbjct: 3298 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LH 3351
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
A P DS Y C V N+ G+ A L V S A+ IP T +++ T L
Sbjct: 3352 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3411
Query: 2710 EL----VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ C + ++ WFK+ Q+P Q DGV R I N GTY
Sbjct: 3412 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQ-----DGVLR--IQNLDQSCQGTY 3464
Query: 2766 TCKA 2769
C+A
Sbjct: 3465 ICQA 3468
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 17/212 (8%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
R PV S T +G C + + P ++ W L++ + +IT
Sbjct: 3020 RSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPN--GSIIT 3077
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAE 2708
++ PS+ Y C N G + NL V+ P+ P P + +
Sbjct: 3078 --IVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--------VG 3127
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ LEC G+P W + P+ + + L D L I + P D+GTY C
Sbjct: 3128 KAVTLECVSAGEPRSSARWTRISST-PAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3186
Query: 2769 AENSVWTDQ-ITHFVNFTGRESQVSPNVVTAE 2799
A+N++ T Q + TG + +P V E
Sbjct: 3187 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE 3218
Score = 54.8 bits (126), Expect = 5e-06
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 21/169 (12%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+T V G V+ C + P VTW + G L R +V + + + +D+
Sbjct: 3498 QTVVVGHAVEFECLALGDPKPQVTWSKVGGHL------RPGIVQSGGVVRIAHVELADAG 3551
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y CT N G + L V +A P + + +R A + V C G P
Sbjct: 3552 QYRCTATNAAGTTQSHVLLLV----QALP-QISMPQEVRVP---AGSAAVFPCIASGYPT 3603
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
P I+W K D +P D R L + + L + + P+D+GTY C A N
Sbjct: 3604 PDISWSKLDGSLPPDSR-----LENNM--LMLPSVRPQDAGTYVCTATN 3645
Score = 53.6 bits (123), Expect = 1e-05
Identities = 85/358 (23%), Positives = 126/358 (35%), Gaps = 50/358 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G+ V W K G G + ++ L + ++ D G
Sbjct: 2936 VTEGQTLDLNCVVPGQAHAQVTWYKRG-------GSLPARHQTHGSQLRLHLVSPADSGE 2988
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A + G A V TV ++ R RS + D PP T VQ
Sbjct: 2989 YVCRAASGPGPEQE-ASFTV----TVPPSEGSSYRLRSPVISID-PPSST-------VQQ 3035
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
C + G+ P + W +E+ N + + I T + G Y
Sbjct: 3036 GQDASFKCLIHDGAAPISLEWKTRNQEL----EDNVHISPNGSIITIVGTRPSNHGTYRC 3091
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N G L V V PE P++ + G + + V P
Sbjct: 3092 VASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVW-VKVGKAVTLECVSAGEPRSSAR 3145
Query: 3301 WYRDGVRLRPSRRAIMTLD-RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
W R + P++ T D L +++ DAG Y C A N +G A +VEVI
Sbjct: 3146 WTR--ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK--QVEVI 3201
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P P V ++E + EA G T + C G P P ++W
Sbjct: 3202 VDTGAMAPGAPQV-------QAEEAEL-----TVEA--GHTATLRCSATGSPAPTIHW 3245
Score = 53.6 bits (123), Expect = 1e-05
Identities = 74/359 (20%), Positives = 129/359 (35%), Gaps = 45/359 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L CS S PT+ W + L + L ++ +L TL + DS +
Sbjct: 3222 TVEAGHTATLRCSATGSPAPTIHWSK----LRSPLPWQHRLEGD--TLIIPRVAQQDSGQ 3275
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C + G + L V A+ +P + +T L +C G P
Sbjct: 3276 YICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL-------QCLAHGTPPL 3328
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W + +P GR A L + PEDSG Y C+ N V + + +
Sbjct: 3329 TFQWSRVGSSLP--GRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3381
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
G + + A T + + + G ++ A G T++
Sbjct: 3382 VQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG-ASVEFHCAVPSDRG---------TQL 3431
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +EG + + V+ G+ L + ++ ++ G Y C+A G +A + +
Sbjct: 3432 RWFKEGGQLPPGHS-----VQDGV--LRIQNLDQSCQGTYICQAHGPWGKAQASAQLVI- 3483
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPG--EPCVVDGG 2960
P+V++ + VG + G+PKP+ ++ G P +V G
Sbjct: 3484 -----QALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG 3537
Score = 47.2 bits (107), Expect = 0.001
Identities = 47/185 (25%), Positives = 69/185 (37%), Gaps = 18/185 (9%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L CQV GSPP W ++ V + ++Q + H + P+ D GVY T RN
Sbjct: 1696 LRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPS---DAGVYICTCRNLH 1752
Query: 3247 GAVSCHCGLVV----DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+ + L+V K I V + + P D I P+ + W
Sbjct: 1753 QSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP-----GADVTFICTAKSKSPAYTLVW- 1806
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
RL + +D +G L + V DAG Y CT SN + + V +
Sbjct: 1807 ---TRLHNGKLPTRAMDFNG--ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASG 1861
Query: 3363 QTSEP 3367
S P
Sbjct: 1862 TLSAP 1866
Score = 47.2 bits (107), Expect = 0.001
Identities = 75/360 (20%), Positives = 128/360 (35%), Gaps = 35/360 (9%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SS++ V G P + I P ++ G+T +L C V G+ V W K G G
Sbjct: 2815 SSAVHVPAPGGAPP-IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRG-------GN 2866
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ ++ L + ++ D G YSC+ T G + T +VT +
Sbjct: 2867 LPARHQVHGPLLRLNQVSPADSGEYSCQVT---GSSGTLEASVLVT--------IEPSSP 2915
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
G P + + V + L C V G +V+WYK G + R++
Sbjct: 2916 GPIPAPGLAQPIY-IEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL---PARHQT 2971
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSG---AVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
Q ++P D G Y A + G S + +G +
Sbjct: 2972 HGSQLRLHLVSPA---DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDP 3028
Query: 3275 PLYKLHEGDELRISAVV-EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
P + +G + ++ + + + W L + + + +G I + +
Sbjct: 3029 PSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VHISPNGSI-ITIVGTRP 3083
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
+ G Y C ASN G A + + V G S PV + + E + +PRSS
Sbjct: 3084 SNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSS 3143
Score = 46.0 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+T TC G P P + W N + R+T G L I+D+ D+G Y+C
Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHP-RVTVTSEGGRGTLIIRDVKESDQGAYTC 479
Query: 3125 EATNTHG 3131
EA N G
Sbjct: 480 EAMNARG 486
Score = 41.9 bits (94), Expect = 0.039
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 18/170 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ V+ C+V S + W++ G +L + DG++ ++ L+ S Y C
Sbjct: 3414 GASVEFHCAVPSDRGTQLRWFKEG----GQLPPGHSVQDGVLRIQNLDQ--SCQGTYICQ 3467
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
G SA L + +A P R+ T + + + EC G P P++TW
Sbjct: 3468 AHGPWGKAQASAQLVI----QALPSVLINIRTSVQTV-VVGHAVEFECLALGDPKPQVTW 3522
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K + G Q+ GV R+A + D+G Y C A N+ T Q
Sbjct: 3523 SKVGGHL-RPGIVQS----GGVVRIA--HVELADAGQYRCTATNAAGTTQ 3565
Score = 39.9 bits (89), Expect = 0.16
Identities = 53/234 (22%), Positives = 78/234 (33%), Gaps = 40/234 (17%)
Query: 3031 WGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
WG++ ++ + L ++I ++ G C G P P V W K G
Sbjct: 3472 WGKAQASAQLVIQALPS---VLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH 3528
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
+ Q G + I + + D G+Y C ATN G ++ L V
Sbjct: 3529 LRPGI----VQSGGV---VRIAHVELADAGQYRCTATNAAGTTQSHVLLLV--------- 3572
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
PQ +M ++ RV A C G P P +SW K +
Sbjct: 3573 --------------QALPQISMP-QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPP 3617
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
D R + L + D G Y TA N G V L V + + Y
Sbjct: 3618 DSRLEN------NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPY 3665
Score = 38.3 bits (85), Expect = 0.48
Identities = 24/72 (33%), Positives = 32/72 (44%)
Query: 2823 QVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
Q +RG T+ G PT + R + V E G TL + DV E++ G
Sbjct: 417 QASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGA 476
Query: 2883 YTCRAWSAHGNV 2894
YTC A +A G V
Sbjct: 477 YTCEAMNARGMV 488
Score = 34.7 bits (76), Expect = 5.9
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 10/105 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
GS C P ++W + LD L +L + ++ L + P D+ Y CT
Sbjct: 3589 GSAAVFPCIASGYPTPDISWSK----LDGSLPPDSRLENNMLMLPSVR--PQDAGTYVCT 3642
Query: 2668 VENENGAISTSANL----KVYPSFEASPIPPTFTRSIRDTFHLAE 2708
N G + A+L +V P F +P +I+D + E
Sbjct: 3643 ATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFE 3687
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 84.2 bits (199), Expect = 7e-15
Identities = 98/366 (26%), Positives = 133/366 (36%), Gaps = 49/366 (13%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V I P QL + G+ A CS G P P + W G++ ++ L +
Sbjct: 1847 VSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGG------PGGQLPAKAQIHGGILRLP 1900
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D+ +Y C A H A AV+ V G P+ +
Sbjct: 1901 AVEPTDQAQYLCRA---HSSAGQQVARAVL------------------HVHGGGGPRVQV 1939
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+V A VRL C+ G P ++W K+G + R + TL I
Sbjct: 1940 SPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSER---TDIATLLIPAITT 1996
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A + +G +VV A P P + EG L ++ VV
Sbjct: 1997 ADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSP--SVTEGQTLDLNCVVA 2054
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
VTWYR G L P + G L L V+ D+G Y C N G
Sbjct: 2055 GSAHAQVTWYRRGGSLPPHTQV------HGS-RLRLPQVSPADSGEYVCRVENGSGPKEA 2107
Query: 3353 SGKVEVI-GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S V V+ GT S P P VP S P+ I +P SS EG T+ + C V G
Sbjct: 2108 SITVSVLHGTH--SGPSYTP------VPGSTRPIRI-EPSSSHVAEGQTLDLNCVVPGQA 2158
Query: 3412 KPDVYW 3417
V W
Sbjct: 2159 HAQVTW 2164
Score = 81.4 bits (192), Expect = 5e-14
Identities = 91/357 (25%), Positives = 151/357 (42%), Gaps = 44/357 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R ++ L+ L ++ P+DS EYSC
Sbjct: 2819 EGQTLDLKCVVPGQAHAQVTWHKRG----GNLPARHQVHGPLLRLNQVS--PADSGEYSC 2872
Query: 2667 TVENENGAISTSANLKVYPSFEASPIP-PTFTRSI---RDTFHLAENE-LVLECRIRGQP 2721
V +G + S + + PS PIP P + I + H+ E + L L C + GQ
Sbjct: 2873 QVTGSSGTLEASVLVTIEPS-SPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQA 2931
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
++TW+K +P+ R+Q +L + +P DSG Y C+A + +Q F
Sbjct: 2932 HAQVTWYKRGGSLPA--RHQTH-----GSQLRLHLVSPADSGEYVCRAASGPGPEQEASF 2984
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V P+ ++ + R S++ P V Q + + + P
Sbjct: 2985 T------VTVPPSEGSSYRLRSPVISID---PPSSTV----QQGQDASFKCLIHDGAAPI 3031
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+EW + E+ N + + T+ + G Y C A +A+G A +
Sbjct: 3032 SLEWKTRNQ---ELEDNVHISPNGSIITIV--GTRPSNHGTYRCVASNAYG-----VAQS 3081
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
VV S + G P V V PE + + VG+ + + + GEP+ A RI P ++
Sbjct: 3082 VVNLS-VHGPPTVSV-LPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLE 3136
Score = 80.2 bits (189), Expect = 1e-13
Identities = 85/321 (26%), Positives = 132/321 (41%), Gaps = 39/321 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T VEG + L C V +TWY+ G L R + + L ++ +DS E
Sbjct: 2619 TVVEGQTLDLNCVVARQPQAIITWYKRG----GSLPSRHQTHGSHLRLHQMSV--ADSGE 2672
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---DTFHLAENE-LVLECRIRG 2719
Y C N A+ S + V PS SP P + IR + H+AE E L L C + G
Sbjct: 2673 YVCRANNNIDALEASIVISVSPS-AGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2731
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
Q ++TW K +PS + + RL + + +P DSG Y C+ S + +
Sbjct: 2732 QAHAQVTWHKRGGSLPSHHQTRG-------SRLRLHHVSPADSGEYVCRVMGSSGPLEAS 2784
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V S I + SR VA G T+ L+ + G
Sbjct: 2785 VLVTIEASGSSAVHVPAPGGAPPIRIEPSSSR------------VAEGQTLDLKCVVPGQ 2832
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G ++ AR V L L L+ V+ +SG Y+C+ + G ++ +
Sbjct: 2833 AHAQVTWHKRGGNLP-----ARHQVHGPL--LRLNQVSPADSGEYSCQVTGSSGTLEASV 2885
Query: 2899 AITVVQPSDLDGKPAVIVGRP 2919
+T ++PS PA + +P
Sbjct: 2886 LVT-IEPSSPGPIPAPGLAQP 2905
Score = 78.2 bits (184), Expect = 5e-13
Identities = 91/356 (25%), Positives = 147/356 (41%), Gaps = 46/356 (12%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTA--VEGSRVKLTCSVISSSDPTVTW 2627
S EA +++ ++ LS + ++ + + +A G + L C V S + T+TW
Sbjct: 2487 SSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITW 2546
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
Y+ G L R ++V L + P+DS EY C V N G+ TS + + S
Sbjct: 2547 YKRG----GSLPSRHQIVGS--RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG 2600
Query: 2688 EA---SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+ S PP S T + L L C + QP ITW+K +PS R+Q
Sbjct: 2601 SSHVPSVSPPIRIESSSPTV-VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RHQTHG 2657
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
L + + DSG Y C+A N++ D + + + S SP+ +
Sbjct: 2658 -----SHLRLHQMSVADSGEYVCRANNNI--DALEASIVISVSPSAGSPSAPGSSMP--- 2707
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFV 2863
+ES H VA G T+ L + G +V W + G S+ ++
Sbjct: 2708 -IRIESSSSH---------VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQT----- 2752
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP 2919
+G L L V+ +SG Y CR + G ++ + +T+ + G AV V P
Sbjct: 2753 -RG-SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI----EASGSSAVHVPAP 2802
Score = 76.2 bits (179), Expect = 2e-12
Identities = 91/358 (25%), Positives = 132/358 (36%), Gaps = 60/358 (16%)
Query: 3065 GETANLTCSVKGK-PVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G C+ K K P +VW + + G++ ++ F+ LTI+++ + D G Y
Sbjct: 1765 GADVTFICTAKSKSPAYTLVWTRLHN------GKLPTRAMDFNGILTIRNVQLSDAGTYV 1818
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C +N A L V T+ SA V +PPQ T VQ
Sbjct: 1819 CTGSNMFAMDQGTATLHVQASGTL-----------SAPVVSIHPPQLT-------VQPGQ 1860
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C GSP P + W G + + + PT D Y A
Sbjct: 1861 LAEFRCSATGSPTPTLEW--TGGPGGQLPAKAQIHGGILRLPAVEPT---DQAQYLCRAH 1915
Query: 3244 NNSGAVSCHCGLVV--DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+++G L V G R V+PE ++H G +R+ PS +TW
Sbjct: 1916 SSAGQQVARAVLHVHGGGGPRVQVSPE-------RTQVHAGRTVRLYCRAAGVPSATITW 1968
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++G L P R+ +R L + A+TT DAG Y C A++ G A +V V+
Sbjct: 1969 RKEGGSLPPQARS----ERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSA 2024
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
S PPV I P EG T+ + C V G V W R
Sbjct: 2025 SDASP---PPVKIESSSP--------------SVTEGQTLDLNCVVAGSAHAQVTWYR 2065
Score = 74.9 bits (176), Expect = 5e-12
Identities = 78/298 (26%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R + L+ L P+DS EY C
Sbjct: 2144 EGQTLDLNCVVPGQAHAQVTWHKRG----GSLPARHQTHGSLLRLH--QVTPADSGEYVC 2197
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKI 2725
V +G + S + + S PIPP S T +AE + L L C + GQ ++
Sbjct: 2198 HVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSST--VAEGQTLDLSCVVAGQAHAQV 2255
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
TW+K +P+ R+Q RL I +P D+G Y C+A N
Sbjct: 2256 TWYKRGGSLPA--RHQV-----RGSRLYIFQASPADAGQYVCRASN-------------- 2294
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVE 2844
G E+ ++ V + +A + S +P + QVA G T+ L + G +V
Sbjct: 2295 GMEASITVTVTGTQGANLAYPA-GSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT 2352
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
W + G S+ ++ G L L + +SG Y CR + ++ + +T+
Sbjct: 2353 WHKRGGSLPVRHQT------HG-SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2403
Score = 69.7 bits (163), Expect = 2e-10
Identities = 90/327 (27%), Positives = 135/327 (41%), Gaps = 56/327 (17%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
LS + P + + EG + L C V S+ VTWYR G L + V
Sbjct: 2022 LSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQ-----V 2076
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASP--IP-PTFTRSIR- 2701
G L + P+DS EY C VEN +G S + V + P P P TR IR
Sbjct: 2077 HG-SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRI 2135
Query: 2702 --DTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPT 2758
+ H+AE + L L C + GQ ++TW K +P+ R+Q L + T
Sbjct: 2136 EPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RHQTH-----GSLLRLHQVT 2188
Query: 2759 PEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
P DSG Y C + + + V E+ V P + + +ES
Sbjct: 2189 PADSGEYVCHVVGTSGPLEASVLVTI---EASVIPGPIPPVR-------IES-------- 2230
Query: 2819 LTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVY--RNARVFVEQGLYTLALSDV 2875
+ VA G T+ L + G +V W + G S+ + R +R+++ Q
Sbjct: 2231 -SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ---------A 2280
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITV 2902
+ ++G Y CRA ++G M A+ITV
Sbjct: 2281 SPADAGQYVCRA--SNG---MEASITV 2302
Score = 68.9 bits (161), Expect = 3e-10
Identities = 82/312 (26%), Positives = 124/312 (39%), Gaps = 41/312 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V S VTW++ G L R + L+ L A P+DS EY C
Sbjct: 2333 EGQTLDLNCVVPGQSHAQVTWHKRG----GSLPVRHQTHGSLLRL--YQASPADSGEYVC 2386
Query: 2667 TVENENGAISTSANLKVYP--SFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP 2723
V + + S + + P S A + PT R + +AE + L L C + GQ
Sbjct: 2387 RVLGSSVPLEASVLVTIEPAGSVPALGVTPT-VRIESSSSQVAEGQTLDLNCLVAGQAHA 2445
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW K +P+ R+Q RL + TP DSG Y C+ S T + + V
Sbjct: 2446 QVTWHKRGGSLPA--RHQVH-----GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVT 2498
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTR 2842
R S S + A RI S +A G T+ L + P
Sbjct: 2499 IQQRLSG-SHSQGVAYPVRIESSSA--------------SLANGHTLDLNCLVASQAPHT 2543
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + G S+ ++ L + VT +SG Y C + G+ + + +T
Sbjct: 2544 ITWYKRGGSLPSRHQIVG-------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVT- 2595
Query: 2903 VQPSDLDGKPAV 2914
+Q S P+V
Sbjct: 2596 IQGSGSSHVPSV 2607
Score = 65.7 bits (153), Expect = 3e-09
Identities = 84/342 (24%), Positives = 134/342 (39%), Gaps = 36/342 (10%)
Query: 2602 DRTAVEGSR-VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+RT V R V+L C T+TW + G L + R + D + TL + +D
Sbjct: 1942 ERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQA--RSERTD-IATLLIPAITTAD 1998
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C + G + V + +ASP PP S + + L L C + G
Sbjct: 1999 AGFYLCVATSPAGTAQARIQVVVLSASDASP-PPVKIESSSPSVTEGQT-LDLNCVVAGS 2056
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
++TW++ +P + RL + +P DSG Y C+ EN + +
Sbjct: 2057 AHAQVTWYRRGGSLPPHTQVHG-------SRLRLPQVSPADSGEYVCRVENGSGPKEASI 2109
Query: 2781 FVN-FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V+ G S S V TR R +E H VA G T+ L + G
Sbjct: 2110 TVSVLHGTHSGPSYTPVPG-STRPIR--IEPSSSH---------VAEGQTLDLNCVVPGQ 2157
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G S+ AR L L L VT +SG Y C G ++ +
Sbjct: 2158 AHAQVTWHKRGGSLP-----ARHQTHGSL--LRLHQVTPADSGEYVCHVVGTSGPLEASV 2210
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
+T ++ S + G P V ++ G+ +++S G+
Sbjct: 2211 LVT-IEASVIPG-PIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2250
Score = 65.3 bits (152), Expect = 4e-09
Identities = 92/374 (24%), Positives = 137/374 (36%), Gaps = 58/374 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V + P + ++ AG T L C G P + W K G + +A + L I
Sbjct: 1937 VQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDI----ATLLIP 1992
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
I D G Y C AT+ G A AR+ VV + +DA PP +
Sbjct: 1993 AITTADAGFYLCVATSPAGTAQ--ARIQVVV---LSASDAS-------------PPPVKI 2034
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L C V GS +V+WY+ G + + + +++P
Sbjct: 2035 ESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPHTQVHGSRLRLPQVSPA-- 2089
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG------LEPLYK-LHEGDEL 3285
D G Y N SG + V G + + G +EP + EG L
Sbjct: 2090 -DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTL 2148
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
++ VV VTW++ G L P+R G + L L VT D+G Y C
Sbjct: 2149 DLNCVVPGQAHAQVTWHKRGGSL-PARH-----QTHGSL-LRLHQVTPADSGEYVC---- 2197
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIEC 3405
V+GT E + + + +P P+ I + SS EG T+ + C
Sbjct: 2198 -----------HVVGTSGPLEASVLVTIEASVIPGPIPPVRI-ESSSSTVAEGQTLDLSC 2245
Query: 3406 EVVGDPKPDVYWLR 3419
V G V W +
Sbjct: 2246 VVAGQAHAQVTWYK 2259
Score = 62.1 bits (144), Expect = 3e-08
Identities = 87/356 (24%), Positives = 128/356 (35%), Gaps = 46/356 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G T +L C V + + W K G G + S+ L I + D G Y C
Sbjct: 2527 GHTLDLNCLVASQAPHTITWYKRG-------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2579
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+N G T +VT ++ S+ V PP + V
Sbjct: 2580 HVSNGAGSRETSL---IVT----------IQGSGSSHVPSVSPP-IRIESSSPTVVEGQT 2625
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ L C V P ++WYK G + +++Q H L + ++ D G Y A N
Sbjct: 2626 LDLNCVVARQPQAIITWYKRGGSLP-----SRHQTHGSH-LRLHQMSVADSGEYVCRANN 2679
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRISAVVEAYPSVGVTW 3301
N A+ + V + AP + + EG+ L ++ VV VTW
Sbjct: 2680 NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTW 2739
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++ G L PS G L L V+ D+G Y C G S V I
Sbjct: 2740 HKRGGSL-PSHHQTR-----GS-RLRLHHVSPADSGEYVCRVMGSSGPLEASVLV-TIEA 2791
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+S +P P P+ I +P SS EG T+ ++C V G V W
Sbjct: 2792 SGSSAVHVP-------APGGAPPIRI-EPSSSRVAEGQTLDLKCVVPGQAHAQVTW 2839
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/310 (27%), Positives = 121/310 (39%), Gaps = 51/310 (16%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG + L+C V + VTWY+ G L + + R L + A P+D+ +
Sbjct: 2234 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGS------RLYIFQASPADAGQ 2287
Query: 2664 YSCTVENENGAIST-------SANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLEC 2715
Y C N A T ANL YP+ PI R + +AE + L L C
Sbjct: 2288 YVCRASNGMEASITVTVTGTQGANL-AYPAGSTQPI-----RIEPSSSQVAEGQTLDLNC 2341
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ GQ ++TW K +P R+Q + RL +P DSG Y C+ S +
Sbjct: 2342 VVPGQSHAQVTWHKRGGSLPV--RHQTH---GSLLRLY--QASPADSGEYVCRVLGS--S 2392
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ V T + P + RI S QVA G T+ L
Sbjct: 2393 VPLEASVLVTIEPAGSVPALGVTPTVRIESSS--------------SQVAEGQTLDLNCL 2438
Query: 2836 IRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
+ G +V W + G S+ AR V L L VT +SG Y CR + G
Sbjct: 2439 VAGQAHAQVTWHKRGGSLP-----ARHQVHGS--RLRLLQVTPADSGEYVCRVVGSSGTQ 2491
Query: 2895 DMNAAITVVQ 2904
+ + +T+ Q
Sbjct: 2492 EASVLVTIQQ 2501
Score = 60.9 bits (141), Expect = 8e-08
Identities = 80/364 (21%), Positives = 135/364 (37%), Gaps = 50/364 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ G+T +L C V +P + W K G G + S+ L + +++ D G
Sbjct: 2620 VVEGQTLDLNCVVARQPQAIITWYKRG-------GSLPSRHQTHGSHLRLHQMSVADSGE 2672
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A N ++V S G P + V
Sbjct: 2673 YVCRANNNIDALEASIVISVSPSAG------------SPSAPGSSMP-IRIESSSSHVAE 2719
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + ++ + + ++P D G Y
Sbjct: 2720 GETLDLNCVVPGQAHAQVTWHKRGGSL---PSHHQTRGSRLRLHHVSPA---DSGEYVCR 2773
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY------KLHEGDELRISAVVEAYP 3295
+SG + + ++ + V G P+ ++ EG L + VV
Sbjct: 2774 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQA 2833
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
VTW++ G L P+R + G + L L V+ D+G Y+C + G S
Sbjct: 2834 HAQVTWHKRGGNL-PARHQV-----HGPL-LRLNQVSPADSGEYSCQVTGSSGTLEASVL 2886
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T EP P + +P + +P++I + SS EG T+ + C V G V
Sbjct: 2887 V-------TIEPSSPGPIPAPGLA---QPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQV 2935
Query: 3416 YWLR 3419
W +
Sbjct: 2936 TWYK 2939
Score = 60.5 bits (140), Expect = 1e-07
Identities = 92/366 (25%), Positives = 135/366 (36%), Gaps = 70/366 (19%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L + AG TA L CS G P P + W K + + R+ L I + D
Sbjct: 3199 ELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQH-RLEGD------TLIIPRVAQQD 3251
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y C AT+ G A L V + PP T
Sbjct: 3252 SGQYICNATSPAGHAEATIILHV-----------------------ESPPYATTVPEHAS 3288
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
VQA V+L C G+PP W + G + R ++E H AP +D G Y
Sbjct: 3289 VQAGETVQLQCLAHGTPPLTFQWSRVGSSL---PGRATARNELLHFERAAP---EDSGRY 3342
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR-ISAVVE---AY 3294
N G+ L+V + A G P ++ E + I A VE A
Sbjct: 3343 RCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAV 3402
Query: 3295 PS---VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
PS + W+++G +L P +DG L + + G Y C A G+A
Sbjct: 3403 PSDRGTQLRWFKEGGQLPPGHSV-----QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQ 3455
Query: 3352 TSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S ++ + +P V+I ++ S + + + G V EC +GDP
Sbjct: 3456 ASAQLVI--------QALPSVLI--NIRTSVQTVVV----------GHAVEFECLALGDP 3495
Query: 3412 KPDVYW 3417
KP V W
Sbjct: 3496 KPQVTW 3501
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/372 (22%), Positives = 134/372 (36%), Gaps = 54/372 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P ++ G+T +L C V G+ V W K G G + + L +
Sbjct: 2322 IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG-------GSLPVRHQTHGSLLRLY 2374
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG-DYPPQFT 3171
+ D G Y C V+ EA + E + V P
Sbjct: 2375 QASPADSGEYVCR---------------VLGSSVPLEASVLVTIEPAGSVPALGVTPTVR 2419
Query: 3172 MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
+ +V + L C V G +V+W+K G + R++ + L++ P
Sbjct: 2420 IESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL---PARHQVHGSRLRLLQVTPA- 2475
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRIS 3288
D G Y +SG + + + + + + L G L ++
Sbjct: 2476 --DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLN 2533
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+V + +TWY+ G L PSR I+ G L + VT D+G Y C SN G
Sbjct: 2534 CLVASQAPHTITWYKRGGSL-PSRHQIV-----GS-RLRIPQVTPADSGEYVCHVSNGAG 2586
Query: 3349 RASTSGKVEVIGTDQTSEPRI-PPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
TS V + G+ + P + PP+ I S P + EG T+ + C V
Sbjct: 2587 SRETSLIVTIQGSGSSHVPSVSPPIRIE-----SSSPTVV---------EGQTLDLNCVV 2632
Query: 3408 VGDPKPDVYWLR 3419
P+ + W +
Sbjct: 2633 ARQPQAIITWYK 2644
Score = 58.8 bits (136), Expect = 3e-07
Identities = 75/327 (22%), Positives = 119/327 (36%), Gaps = 40/327 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET +L C V G+ V W K G G + S L + ++ D G
Sbjct: 2717 VAEGETLDLNCVVPGQAHAQVTWHKRG-------GSLPSHHQTRGSRLRLHHVSPADSGE 2769
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C + G + + +A G PP + RV
Sbjct: 2770 YVCRVMGSSGPLEASVLVTI---------EASGSSAVHVPAPGGAPP-IRIEPSSSRVAE 2819
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ +++P D G Y
Sbjct: 2820 GQTLDLKCVVPGQAHAQVTWHKRGGNL---PARHQVHGPLLRLNQVSPA---DSGEYSCQ 2873
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLY------KLHEGDELRISAVVEAY 3294
+SG + + ++ + AP +P+Y + EG L ++ VV
Sbjct: 2874 VTGSSGTLEASVLVTIEPSSPGPIPAPGLA---QPIYIEASSSHVTEGQTLDLNCVVPGQ 2930
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
VTWY+ G L P+R Q+ L L V+ D+G Y C A++ G +
Sbjct: 2931 AHAQVTWYKRGGSL-PARHQT----HGSQLRLHL--VSPADSGEYVCRAASGPGPEQEAS 2983
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ + S R+ VIS D P S
Sbjct: 2984 FTVTVPPSEGSSYRLRSPVISIDPPSS 3010
Score = 57.6 bits (133), Expect = 7e-07
Identities = 87/368 (23%), Positives = 133/368 (36%), Gaps = 43/368 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P V I + G+T +L C V G V W + G + +Q +G L
Sbjct: 2029 PPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPH-----TQVHGSR--L 2081
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ ++ D G Y C N G ++V+ V G P
Sbjct: 2082 RLPQVSPADSGEYVCRVENGSGPKEASITVSVL--------HGTHSGPSYTPVPGSTRP- 2132
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
+ V + L C V G +V+W+K G + R++ ++ P
Sbjct: 2133 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSL---PARHQTHGSLLRLHQVTP 2189
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
D G Y SG + + ++ + P + EG L +S
Sbjct: 2190 A---DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSS-TVAEGQTLDLSC 2245
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTWY+ G L P+R + R ++ + A+ DAG Y C ASN +
Sbjct: 2246 VVAGQAHAQVTWYKRGGSL-PARHQV----RGSRLYIFQASPA--DAGQYVCRASNGMEA 2298
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+ T V V GT Q + P S +P+ I +P SS+ EG T+ + C V G
Sbjct: 2299 SIT---VTVTGT-QGANLAYPAG--------STQPIRI-EPSSSQVAEGQTLDLNCVVPG 2345
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2346 QSHAQVTW 2353
Score = 57.6 bits (133), Expect = 7e-07
Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 54/401 (13%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKILAGETANLTCSVKGKPV 3079
+R N YG +S V L+ P V +LP G + + G+ L C G+P
Sbjct: 3068 YRCVASNAYGVAQSV-------VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPR 3120
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
W + + + T L I D G Y C A N G A +
Sbjct: 3121 SSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3179
Query: 3140 AVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKV 3199
V T A G PQ + V+A + L C GSP P +
Sbjct: 3180 IVDT---------------GAMAPG--APQVQAEEAELTVEAGHTATLRCSATGSPAPTI 3222
Query: 3200 SWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK 3259
W K + + R + TL I D G Y A + +G L V+
Sbjct: 3223 HWSKLRSPLPWQHRL------EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVES 3276
Query: 3260 GIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD 3319
A PE + G+ +++ + P + W R G L P R
Sbjct: 3277 PPYATTVPEHA-------SVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATA---- 3324
Query: 3320 RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVP 3379
R+ + AA D+G Y C +N+VG A ++ V G P + + +P
Sbjct: 3325 RNELLHFERAA--PEDSGRYRCRVTNKVGSAEAFAQLLVQGP--------PGSLPATSIP 3374
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+ G +V C V D + W ++
Sbjct: 3375 AGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKE 3415
Score = 57.6 bits (133), Expect = 7e-07
Identities = 73/313 (23%), Positives = 114/313 (36%), Gaps = 50/313 (15%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF 3105
AG P V + P G + C+V + W K G G++ +
Sbjct: 3375 AGSTPT-VQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEG-------GQLPPGHSVQ 3426
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
D L I++++ +G Y C+A GKA A+L + +V
Sbjct: 3427 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL----------------- 3469
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
+R + V + V C +G P P+V+W K G + R Q +
Sbjct: 3470 ----INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL----RPGIVQSGG--VV 3519
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
IA L D G Y TA N +G H L+V P+ E ++ G
Sbjct: 3520 RIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ------ALPQISMPQE--VRVPAGSAA 3571
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ YP+ ++W + L P R + L L +V +DAG Y CTA+N
Sbjct: 3572 VFPCIASGYPTPDISWSKLDGSLPPDSRLENNM-------LMLPSVRPQDAGTYVCTATN 3624
Query: 3346 EVGRASTSGKVEV 3358
G+ ++V
Sbjct: 3625 RQGKVKAFAHLQV 3637
Score = 56.4 bits (130), Expect = 2e-06
Identities = 74/311 (23%), Positives = 115/311 (36%), Gaps = 42/311 (13%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S T G + CS S PT+ W +L + ++ G++ L
Sbjct: 1845 PVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGP---GGQLPAKAQIHGGILRLPA 1901
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ P+D A+Y C + G A L V+ P R H A + L
Sbjct: 1902 VE--PTDQAQYLCRAHSSAGQQVARAVLHVH----GGGGPRVQVSPERTQVH-AGRTVRL 1954
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
CR G P ITW K+ +P R + + L I T D+G Y C A +
Sbjct: 1955 YCRAAGVPSATITWRKEGGSLPPQARSE----RTDIATLLIPAITTADAGFYLCVATSPA 2010
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
T Q +++ V++A +ES P V G T+ L
Sbjct: 2011 GTAQ-----------ARIQVVVLSASDASPPPVKIESSSP---------SVTEGQTLDLN 2050
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G +V W R G S+ + +V + L L V+ +SG Y CR + G
Sbjct: 2051 CVVAGSAHAQVTWYRRGGSLPP---HTQVHGSR----LRLPQVSPADSGEYVCRVENGSG 2103
Query: 2893 NVDMNAAITVV 2903
+ + ++V+
Sbjct: 2104 PKEASITVSVL 2114
Score = 56.4 bits (130), Expect = 2e-06
Identities = 87/368 (23%), Positives = 138/368 (37%), Gaps = 54/368 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P + G+T +L C V G+ V W K G G + ++ L +
Sbjct: 2133 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRG-------GSLPARHQTHGSLLRLH 2185
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D G Y C T G A + V + +V + G PP +
Sbjct: 2186 QVTPADSGEYVCHVVGTSGPLE--ASVLVTIEASV--------------IPGPIPP-VRI 2228
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L+C V G +V+WYK G + R++ + + + + +P
Sbjct: 2229 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL---PARHQVRGSRLYIFQASPA-- 2283
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIR-AYVAPEFC-CGLEPLY-KLHEGDELRISA 3289
D G Y A N A S + +G AY A +EP ++ EG L ++
Sbjct: 2284 -DAGQYVCRASNGMEA-SITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 2341
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTW++ G L P R G + L L + D+G Y C V
Sbjct: 2342 VVPGQSHAQVTWHKRGGSL-PVRH-----QTHGSL-LRLYQASPADSGEYVC----RVLG 2390
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+S + V+ T + + +P + ++P V SS+ EG T+ + C V G
Sbjct: 2391 SSVPLEASVLVTIEPAGS-VPALGVTPTVRIESS--------SSQVAEGQTLDLNCLVAG 2441
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2442 QAHAQVTW 2449
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 21/184 (11%)
Query: 2594 PVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P ++T + + +V+ G V+L C + T W R G L + R +L L
Sbjct: 3277 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LH 3330
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
A P DS Y C V N+ G+ A L V S A+ IP T +++ T L
Sbjct: 3331 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3390
Query: 2710 EL----VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ C + ++ WFK+ Q+P Q DGV R I N GTY
Sbjct: 3391 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQ-----DGVLR--IQNLDQSCQGTY 3443
Query: 2766 TCKA 2769
C+A
Sbjct: 3444 ICQA 3447
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 17/212 (8%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
R PV S T +G C + + P ++ W L++ + +IT
Sbjct: 2999 RSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPN--GSIIT 3056
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAE 2708
++ PS+ Y C N G + NL V+ P+ P P + +
Sbjct: 3057 --IVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--------VG 3106
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ LEC G+P W + P+ + + L D L I + P D+GTY C
Sbjct: 3107 KAVTLECVSAGEPRSSARWTRISST-PAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3165
Query: 2769 AENSVWTDQ-ITHFVNFTGRESQVSPNVVTAE 2799
A+N++ T Q + TG + +P V E
Sbjct: 3166 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE 3197
Score = 54.8 bits (126), Expect = 5e-06
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 21/169 (12%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+T V G V+ C + P VTW + G L R +V + + + +D+
Sbjct: 3477 QTVVVGHAVEFECLALGDPKPQVTWSKVGGHL------RPGIVQSGGVVRIAHVELADAG 3530
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y CT N G + L V +A P + + +R A + V C G P
Sbjct: 3531 QYRCTATNAAGTTQSHVLLLV----QALP-QISMPQEVRVP---AGSAAVFPCIASGYPT 3582
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
P I+W K D +P D R L + + L + + P+D+GTY C A N
Sbjct: 3583 PDISWSKLDGSLPPDSR-----LENNM--LMLPSVRPQDAGTYVCTATN 3624
Score = 53.6 bits (123), Expect = 1e-05
Identities = 85/358 (23%), Positives = 126/358 (35%), Gaps = 50/358 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G+ V W K G G + ++ L + ++ D G
Sbjct: 2915 VTEGQTLDLNCVVPGQAHAQVTWYKRG-------GSLPARHQTHGSQLRLHLVSPADSGE 2967
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A + G A V TV ++ R RS + D PP T VQ
Sbjct: 2968 YVCRAASGPGPEQE-ASFTV----TVPPSEGSSYRLRSPVISID-PPSST-------VQQ 3014
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
C + G+ P + W +E+ N + + I T + G Y
Sbjct: 3015 GQDASFKCLIHDGAAPISLEWKTRNQEL----EDNVHISPNGSIITIVGTRPSNHGTYRC 3070
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N G L V V PE P++ + G + + V P
Sbjct: 3071 VASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVW-VKVGKAVTLECVSAGEPRSSAR 3124
Query: 3301 WYRDGVRLRPSRRAIMTLD-RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
W R + P++ T D L +++ DAG Y C A N +G A +VEVI
Sbjct: 3125 WTR--ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK--QVEVI 3180
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P P V ++E + EA G T + C G P P ++W
Sbjct: 3181 VDTGAMAPGAPQV-------QAEEAEL-----TVEA--GHTATLRCSATGSPAPTIHW 3224
Score = 53.6 bits (123), Expect = 1e-05
Identities = 74/359 (20%), Positives = 129/359 (35%), Gaps = 45/359 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L CS S PT+ W + L + L ++ +L TL + DS +
Sbjct: 3201 TVEAGHTATLRCSATGSPAPTIHWSK----LRSPLPWQHRLEGD--TLIIPRVAQQDSGQ 3254
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C + G + L V A+ +P + +T L +C G P
Sbjct: 3255 YICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL-------QCLAHGTPPL 3307
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W + +P GR A L + PEDSG Y C+ N V + + +
Sbjct: 3308 TFQWSRVGSSLP--GRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3360
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
G + + A T + + + G ++ A G T++
Sbjct: 3361 VQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG-ASVEFHCAVPSDRG---------TQL 3410
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +EG + + V+ G+ L + ++ ++ G Y C+A G +A + +
Sbjct: 3411 RWFKEGGQLPPGHS-----VQDGV--LRIQNLDQSCQGTYICQAHGPWGKAQASAQLVI- 3462
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPG--EPCVVDGG 2960
P+V++ + VG + G+PKP+ ++ G P +V G
Sbjct: 3463 -----QALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG 3516
Score = 47.2 bits (107), Expect = 0.001
Identities = 47/185 (25%), Positives = 69/185 (37%), Gaps = 18/185 (9%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L CQV GSPP W ++ V + ++Q + H + P+ D GVY T RN
Sbjct: 1675 LRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPS---DAGVYICTCRNLH 1731
Query: 3247 GAVSCHCGLVV----DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+ + L+V K I V + + P D I P+ + W
Sbjct: 1732 QSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP-----GADVTFICTAKSKSPAYTLVW- 1785
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
RL + +D +G L + V DAG Y CT SN + + V +
Sbjct: 1786 ---TRLHNGKLPTRAMDFNG--ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASG 1840
Query: 3363 QTSEP 3367
S P
Sbjct: 1841 TLSAP 1845
Score = 47.2 bits (107), Expect = 0.001
Identities = 75/360 (20%), Positives = 128/360 (35%), Gaps = 35/360 (9%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SS++ V G P + I P ++ G+T +L C V G+ V W K G G
Sbjct: 2794 SSAVHVPAPGGAPP-IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRG-------GN 2845
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ ++ L + ++ D G YSC+ T G + T +VT +
Sbjct: 2846 LPARHQVHGPLLRLNQVSPADSGEYSCQVT---GSSGTLEASVLVT--------IEPSSP 2894
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
G P + + V + L C V G +V+WYK G + R++
Sbjct: 2895 GPIPAPGLAQPIY-IEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL---PARHQT 2950
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSG---AVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
Q ++P D G Y A + G S + +G +
Sbjct: 2951 HGSQLRLHLVSPA---DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDP 3007
Query: 3275 PLYKLHEGDELRISAVV-EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
P + +G + ++ + + + W L + + + +G I + +
Sbjct: 3008 PSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VHISPNGSI-ITIVGTRP 3062
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
+ G Y C ASN G A + + V G S PV + + E + +PRSS
Sbjct: 3063 SNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSS 3122
Score = 46.0 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+T TC G P P + W N + R+T G L I+D+ D+G Y+C
Sbjct: 400 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHP-RVTVTSEGGRGTLIIRDVKESDQGAYTC 458
Query: 3125 EATNTHG 3131
EA N G
Sbjct: 459 EAMNARG 465
Score = 41.9 bits (94), Expect = 0.039
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 18/170 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ V+ C+V S + W++ G +L + DG++ ++ L+ S Y C
Sbjct: 3393 GASVEFHCAVPSDRGTQLRWFKEG----GQLPPGHSVQDGVLRIQNLDQ--SCQGTYICQ 3446
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
G SA L + +A P R+ T + + + EC G P P++TW
Sbjct: 3447 AHGPWGKAQASAQLVI----QALPSVLINIRTSVQTV-VVGHAVEFECLALGDPKPQVTW 3501
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K + G Q+ GV R+A + D+G Y C A N+ T Q
Sbjct: 3502 SKVGGHL-RPGIVQS----GGVVRIA--HVELADAGQYRCTATNAAGTTQ 3544
Score = 39.9 bits (89), Expect = 0.16
Identities = 53/234 (22%), Positives = 78/234 (33%), Gaps = 40/234 (17%)
Query: 3031 WGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
WG++ ++ + L ++I ++ G C G P P V W K G
Sbjct: 3451 WGKAQASAQLVIQALPS---VLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH 3507
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
+ Q G + I + + D G+Y C ATN G ++ L V
Sbjct: 3508 LRPGI----VQSGGV---VRIAHVELADAGQYRCTATNAAGTTQSHVLLLV--------- 3551
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
PQ +M ++ RV A C G P P +SW K +
Sbjct: 3552 --------------QALPQISMP-QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPP 3596
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
D R + L + D G Y TA N G V L V + + Y
Sbjct: 3597 DSRLEN------NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPY 3644
Score = 38.3 bits (85), Expect = 0.48
Identities = 24/72 (33%), Positives = 32/72 (44%)
Query: 2823 QVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
Q +RG T+ G PT + R + V E G TL + DV E++ G
Sbjct: 396 QASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGA 455
Query: 2883 YTCRAWSAHGNV 2894
YTC A +A G V
Sbjct: 456 YTCEAMNARGMV 467
Score = 34.7 bits (76), Expect = 5.9
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 10/105 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
GS C P ++W + LD L +L + ++ L + P D+ Y CT
Sbjct: 3568 GSAAVFPCIASGYPTPDISWSK----LDGSLPPDSRLENNMLMLPSVR--PQDAGTYVCT 3621
Query: 2668 VENENGAISTSANL----KVYPSFEASPIPPTFTRSIRDTFHLAE 2708
N G + A+L +V P F +P +I+D + E
Sbjct: 3622 ATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFE 3666
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16 to
1881) protein.
Length = 1897
Score = 83.4 bits (197), Expect = 1e-14
Identities = 84/319 (26%), Positives = 137/319 (42%), Gaps = 33/319 (10%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 16 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 74
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 75 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 127
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 128 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 178
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKL 3279
L+I + D G YE A N++G S L V +R VAP F + P ++
Sbjct: 179 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV--RVRR-VAPRF--SIPPSSQEV 233
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + ++ V P V W L ++ M + R+ L L+ V R A Y
Sbjct: 234 MPGGSVNLTCVAVGAPMPYVKWMMGAEEL--TKEDEMPVGRN---VLELSNV-VRSAN-Y 286
Query: 3340 TCTASNEVGRASTSGKVEV 3358
TC A + +G + +V V
Sbjct: 287 TCVAISSLGMIEATAQVTV 305
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/315 (26%), Positives = 125/315 (39%), Gaps = 36/315 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 22 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 81
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 82 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 140
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 141 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 198
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A NS T R S +P + R+A P F + +V GG
Sbjct: 199 ATNSAGT-----------RYS--APANLYVRVRRVA--------PRFSIPPSSQEVMPGG 237
Query: 2829 TIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
++ L G P V+W+ +T+ + G L LS+V S YTC A
Sbjct: 238 SVNLTCVAVGAPMPYVKWMMGAEELTKEDE-----MPVGRNVLELSNV--VRSANYTCVA 290
Query: 2888 WSAHGNVDMNAAITV 2902
S+ G ++ A +TV
Sbjct: 291 ISSLGMIEATAQVTV 305
Score = 61.3 bits (142), Expect = 6e-08
Identities = 68/266 (25%), Positives = 105/266 (39%), Gaps = 31/266 (11%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 15 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 74
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 75 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 132
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 133 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 190
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D G Y C A+N G R S + V R+ V P F P S
Sbjct: 191 -DQGKYECVATNSAGTRYSAPANLYV---------RVRRVA----------PRFSIPPSS 230
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWL 3418
E G +V + C VG P P V W+
Sbjct: 231 QEVMPGGSVNLTCVAVGAPMPYVKWM 256
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 50 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 109
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 110 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 154
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 155 EISWFKDFLPV 165
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/280 (28%), Positives = 118/280 (42%), Gaps = 46/280 (16%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 19 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 76
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 77 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 124
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 125 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 181
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+ D+G+Y C ATN+ G T + A A L R V P
Sbjct: 182 LQIESSEESDQGKYECVATNSAG--------------TRYSAPANL-YVRVRRV----AP 222
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
+F++ + V V LTC +G+P P V W EE+
Sbjct: 223 RFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEEL 262
Score = 35.9 bits (79), Expect = 2.6
Identities = 13/42 (30%), Positives = 21/42 (50%)
Query: 3383 EPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+P+FI+ P G C+ G+PKP + W++ KV
Sbjct: 22 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV 63
Score = 35.1 bits (77), Expect = 4.5
Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 10/101 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS + + + G V LTC + + P V W +L ++ G LE+
Sbjct: 222 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGA----EELTKEDEMPVGRNVLEL 277
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
N V SA Y+C + G I +A + V +A P PP
Sbjct: 278 SNVV--RSANYTCVAISSLGMIEATAQVTV----KALPKPP 312
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 83.4 bits (197), Expect = 1e-14
Identities = 84/319 (26%), Positives = 137/319 (42%), Gaps = 33/319 (10%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 188
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKL 3279
L+I + D G YE A N++G S L V +R VAP F + P ++
Sbjct: 189 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV--RVRR-VAPRF--SIPPSSQEV 243
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + ++ V P V W L ++ M + R+ L L+ V R A Y
Sbjct: 244 MPGGSVNLTCVAVGAPMPYVKWMMGAEEL--TKEDEMPVGRN---VLELSNV-VRSAN-Y 296
Query: 3340 TCTASNEVGRASTSGKVEV 3358
TC A + +G + +V V
Sbjct: 297 TCVAISSLGMIEATAQVTV 315
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/315 (26%), Positives = 125/315 (39%), Gaps = 36/315 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 208
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A NS T R S +P + R+A P F + +V GG
Sbjct: 209 ATNSAGT-----------RYS--APANLYVRVRRVA--------PRFSIPPSSQEVMPGG 247
Query: 2829 TIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
++ L G P V+W+ +T+ + G L LS+V S YTC A
Sbjct: 248 SVNLTCVAVGAPMPYVKWMMGAEELTKEDE-----MPVGRNVLELSNV--VRSANYTCVA 300
Query: 2888 WSAHGNVDMNAAITV 2902
S+ G ++ A +TV
Sbjct: 301 ISSLGMIEATAQVTV 315
Score = 61.3 bits (142), Expect = 6e-08
Identities = 68/266 (25%), Positives = 105/266 (39%), Gaps = 31/266 (11%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 200
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D G Y C A+N G R S + V R+ V P F P S
Sbjct: 201 -DQGKYECVATNSAGTRYSAPANLYV---------RVRRVA----------PRFSIPPSS 240
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWL 3418
E G +V + C VG P P V W+
Sbjct: 241 QEVMPGGSVNLTCVAVGAPMPYVKWM 266
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/280 (28%), Positives = 118/280 (42%), Gaps = 46/280 (16%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 191
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+ D+G+Y C ATN+ G T + A A L R V P
Sbjct: 192 LQIESSEESDQGKYECVATNSAG--------------TRYSAPANL-YVRVRRV----AP 232
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
+F++ + V V LTC +G+P P V W EE+
Sbjct: 233 RFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEEL 272
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
Score = 35.1 bits (77), Expect = 4.5
Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 10/101 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS + + + G V LTC + + P V W +L ++ G LE+
Sbjct: 232 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGA----EELTKEDEMPVGRNVLEL 287
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
N V SA Y+C + G I +A + V +A P PP
Sbjct: 288 SNVV--RSANYTCVAISSLGMIEATAQVTV----KALPKPP 322
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 83.4 bits (197), Expect = 1e-14
Identities = 84/319 (26%), Positives = 137/319 (42%), Gaps = 33/319 (10%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 188
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKL 3279
L+I + D G YE A N++G S L V +R VAP F + P ++
Sbjct: 189 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV--RVRR-VAPRF--SIPPSSQEV 243
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + ++ V P V W L ++ M + R+ L L+ V R A Y
Sbjct: 244 MPGGSVNLTCVAVGAPMPYVKWMMGAEEL--TKEDEMPVGRN---VLELSNV-VRSAN-Y 296
Query: 3340 TCTASNEVGRASTSGKVEV 3358
TC A + +G + +V V
Sbjct: 297 TCVAISSLGMIEATAQVTV 315
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/315 (26%), Positives = 125/315 (39%), Gaps = 36/315 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 208
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A NS T R S +P + R+A P F + +V GG
Sbjct: 209 ATNSAGT-----------RYS--APANLYVRVRRVA--------PRFSIPPSSQEVMPGG 247
Query: 2829 TIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
++ L G P V+W+ +T+ + G L LS+V S YTC A
Sbjct: 248 SVNLTCVAVGAPMPYVKWMMGAEELTKEDE-----MPVGRNVLELSNV--VRSANYTCVA 300
Query: 2888 WSAHGNVDMNAAITV 2902
S+ G ++ A +TV
Sbjct: 301 ISSLGMIEATAQVTV 315
Score = 61.3 bits (142), Expect = 6e-08
Identities = 68/266 (25%), Positives = 105/266 (39%), Gaps = 31/266 (11%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 200
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D G Y C A+N G R S + V R+ V P F P S
Sbjct: 201 -DQGKYECVATNSAGTRYSAPANLYV---------RVRRVA----------PRFSIPPSS 240
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWL 3418
E G +V + C VG P P V W+
Sbjct: 241 QEVMPGGSVNLTCVAVGAPMPYVKWM 266
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/280 (28%), Positives = 118/280 (42%), Gaps = 46/280 (16%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 191
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+ D+G+Y C ATN+ G T + A A L R V P
Sbjct: 192 LQIESSEESDQGKYECVATNSAG--------------TRYSAPANL-YVRVRRV----AP 232
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
+F++ + V V LTC +G+P P V W EE+
Sbjct: 233 RFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEEL 272
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
Score = 35.1 bits (77), Expect = 4.5
Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 10/101 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS + + + G V LTC + + P V W +L ++ G LE+
Sbjct: 232 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGA----EELTKEDEMPVGRNVLEL 287
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
N V SA Y+C + G I +A + V +A P PP
Sbjct: 288 SNVV--RSANYTCVAISSLGMIEATAQVTV----KALPKPP 322
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 83.4 bits (197), Expect = 1e-14
Identities = 84/319 (26%), Positives = 137/319 (42%), Gaps = 33/319 (10%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 188
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKL 3279
L+I + D G YE A N++G S L V +R VAP F + P ++
Sbjct: 189 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV--RVRR-VAPRF--SIPPSSQEV 243
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + ++ V P V W L ++ M + R+ L L+ V R A Y
Sbjct: 244 MPGGSVNLTCVAVGAPMPYVKWMMGAEEL--TKEDEMPVGRN---VLELSNV-VRSAN-Y 296
Query: 3340 TCTASNEVGRASTSGKVEV 3358
TC A + +G + +V V
Sbjct: 297 TCVAISSLGMIEATAQVTV 315
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/315 (26%), Positives = 125/315 (39%), Gaps = 36/315 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 208
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A NS T R S +P + R+A P F + +V GG
Sbjct: 209 ATNSAGT-----------RYS--APANLYVRVRRVA--------PRFSIPPSSQEVMPGG 247
Query: 2829 TIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
++ L G P V+W+ +T+ + G L LS+V S YTC A
Sbjct: 248 SVNLTCVAVGAPMPYVKWMMGAEELTKEDE-----MPVGRNVLELSNV--VRSANYTCVA 300
Query: 2888 WSAHGNVDMNAAITV 2902
S+ G ++ A +TV
Sbjct: 301 ISSLGMIEATAQVTV 315
Score = 61.3 bits (142), Expect = 6e-08
Identities = 68/266 (25%), Positives = 105/266 (39%), Gaps = 31/266 (11%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 200
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D G Y C A+N G R S + V R+ V P F P S
Sbjct: 201 -DQGKYECVATNSAGTRYSAPANLYV---------RVRRVA----------PRFSIPPSS 240
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWL 3418
E G +V + C VG P P V W+
Sbjct: 241 QEVMPGGSVNLTCVAVGAPMPYVKWM 266
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/280 (28%), Positives = 118/280 (42%), Gaps = 46/280 (16%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 191
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+ D+G+Y C ATN+ G T + A A L R V P
Sbjct: 192 LQIESSEESDQGKYECVATNSAG--------------TRYSAPANL-YVRVRRV----AP 232
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
+F++ + V V LTC +G+P P V W EE+
Sbjct: 233 RFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEEL 272
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
Score = 35.1 bits (77), Expect = 4.5
Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 10/101 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS + + + G V LTC + + P V W +L ++ G LE+
Sbjct: 232 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGA----EELTKEDEMPVGRNVLEL 287
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
N V SA Y+C + G I +A + V +A P PP
Sbjct: 288 SNVV--RSANYTCVAISSLGMIEATAQVTV----KALPKPP 322
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 83.4 bits (197), Expect = 1e-14
Identities = 84/319 (26%), Positives = 137/319 (42%), Gaps = 33/319 (10%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 46 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 104
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 105 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 157
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 158 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 208
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEP-LYKL 3279
L+I + D G YE A N++G S L V +R VAP F + P ++
Sbjct: 209 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV--RVRR-VAPRF--SIPPSSQEV 263
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
G + ++ V P V W L ++ M + R+ L L+ V R A Y
Sbjct: 264 MPGGSVNLTCVAVGAPMPYVKWMMGAEEL--TKEDEMPVGRN---VLELSNV-VRSAN-Y 316
Query: 3340 TCTASNEVGRASTSGKVEV 3358
TC A + +G + +V V
Sbjct: 317 TCVAISSLGMIEATAQVTV 335
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/315 (26%), Positives = 125/315 (39%), Gaps = 36/315 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 52 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 111
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 112 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 170
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 171 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 228
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A NS T R S +P + R+A P F + +V GG
Sbjct: 229 ATNSAGT-----------RYS--APANLYVRVRRVA--------PRFSIPPSSQEVMPGG 267
Query: 2829 TIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
++ L G P V+W+ +T+ + G L LS+V S YTC A
Sbjct: 268 SVNLTCVAVGAPMPYVKWMMGAEELTKEDE-----MPVGRNVLELSNV--VRSANYTCVA 320
Query: 2888 WSAHGNVDMNAAITV 2902
S+ G ++ A +TV
Sbjct: 321 ISSLGMIEATAQVTV 335
Score = 61.3 bits (142), Expect = 6e-08
Identities = 68/266 (25%), Positives = 105/266 (39%), Gaps = 31/266 (11%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 45 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 104
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 105 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 162
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 163 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 220
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D G Y C A+N G R S + V R+ V P F P S
Sbjct: 221 -DQGKYECVATNSAGTRYSAPANLYV---------RVRRVA----------PRFSIPPSS 260
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWL 3418
E G +V + C VG P P V W+
Sbjct: 261 QEVMPGGSVNLTCVAVGAPMPYVKWM 286
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 80 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 139
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 140 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 184
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 185 EISWFKDFLPV 195
Score = 51.2 bits (117), Expect = 6e-05
Identities = 79/280 (28%), Positives = 118/280 (42%), Gaps = 46/280 (16%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 49 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 106
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 107 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 154
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 155 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 211
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+ D+G+Y C ATN+ G T + A A L R V P
Sbjct: 212 LQIESSEESDQGKYECVATNSAG--------------TRYSAPANL-YVRVRRV----AP 252
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
+F++ + V V LTC +G+P P V W EE+
Sbjct: 253 RFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEEL 292
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 29 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 88
Query: 3420 DFLKV 3424
KV
Sbjct: 89 KGKKV 93
Score = 35.1 bits (77), Expect = 4.5
Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 10/101 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS + + + G V LTC + + P V W +L ++ G LE+
Sbjct: 252 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGA----EELTKEDEMPVGRNVLEL 307
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPP 2694
N V SA Y+C + G I +A + V +A P PP
Sbjct: 308 SNVV--RSANYTCVAISSLGMIEATAQVTV----KALPKPP 342
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 83.0 bits (196), Expect = 2e-14
Identities = 91/375 (24%), Positives = 145/375 (38%), Gaps = 48/375 (12%)
Query: 3047 GDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF- 3105
G++P+ + P + + A C GKP P V W K +F
Sbjct: 1850 GEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLK 1909
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
+ L I+ + + D G+Y C A+N HG R+ V+ TV + ++
Sbjct: 1910 NGTLVIRKVQVQDRGQYMCTASNLHG----LDRMVVLLSVTV----------QQPQILAS 1955
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV--VYDKRRNKYQDEQFH 3223
+ T+ L D + + C G+P P++SW V ++ +
Sbjct: 1956 HYQDVTVYLGD-------TIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENR 2008
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGD 3283
TL I + D GVY+ A N +GA S L V + + E LE + L G
Sbjct: 2009 TLSIKEASFSDRGVYKCVASNAAGADSLAIRLHV-AALPPVIHQE---KLENI-SLPPGL 2063
Query: 3284 ELRISAVVEAYPSVGVTW-YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
+ I +A P V W DG ++RPS+ L L + + +D+G Y C
Sbjct: 2064 SIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECV 2123
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVI 3402
A+N VG A + ++ V + RI PR ++ R G T+
Sbjct: 2124 AANLVGSARRTVQLNV--QRAAANARITGT----------------SPRRTDVRYGGTLK 2165
Query: 3403 IECEVVGDPKPDVYW 3417
++C GDP P + W
Sbjct: 2166 LDCSASGDPWPRILW 2180
Score = 66.1 bits (154), Expect = 2e-09
Identities = 86/359 (23%), Positives = 148/359 (41%), Gaps = 49/359 (13%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKL-------KYRKKLVDGLITLEV 2653
D G +K+ C +P ++W +G L+++ + + ++ +V TL
Sbjct: 2252 DHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYF 2311
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV- 2712
+ +Y+C EN+ G +KV + P T + ++V
Sbjct: 2312 NEVGMREEGDYTCFAENQVGKDEMRVRVKVVTA------PATIRNKTYLAVQVPYGDVVT 2365
Query: 2713 LECRIRGQPLPKITWFK-DDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+ C +G+P+PK+TW +K IP S +YQ + DG L I DSG YTC
Sbjct: 2366 VACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIY--QDGT--LLIQKAQRSDSGNYTCLVR 2421
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS D+ T +++ + +++ N P+ + T ++A GG+
Sbjct: 2422 NSAGEDRKTVWIHVNVQPPKINGN------------------PN--PITTVREIAAGGSR 2461
Query: 2831 GL-QVEIRGCPT-RVEW-LREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
L + G PT RV W EG + Y R+ V G +L + + +++S C A
Sbjct: 2462 KLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITV-HGNGSLDIRSLRKSDSVQLVCMA 2520
Query: 2888 WSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
+ G + +TV++P + KP EK I G I+++ G P P V
Sbjct: 2521 RNEGGEARLIVQLTVLEPME---KPIFHDPISEK-ITAMAGHTISLNCSAAGTPTPSLV 2575
Score = 63.3 bits (147), Expect = 1e-08
Identities = 83/352 (23%), Positives = 140/352 (39%), Gaps = 51/352 (14%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYR-NGVLL-DNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
G + + C+ ++ P+V W +G + ++ + V TL + N P DS Y
Sbjct: 2062 GLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYE 2121
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C N G+ + L V + + I T S R T L L+C G P P+I
Sbjct: 2122 CVAANLVGSARRTVQLNVQRAAANARITGT---SPRRTDVRYGGTLKLDCSASGDPWPRI 2178
Query: 2726 TWFKDDKQI-----PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
W K++ D R + F A+G L + + T +D+G Y C A N V D +
Sbjct: 2179 LWRLPSKRMIDALFSFDSRIKVF--ANGT--LVVKSVTDKDAGDYLCVARNKVGDDYVVL 2234
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
V+ + +++ E + + D++V GG + + G P
Sbjct: 2235 KVDVVMKPAKI-----------------EHKEEN------DHKVFYGGDLKVDCVATGLP 2271
Query: 2841 T-RVEW-LREGRSVTEVYRN------ARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ W L +G V ++ + +V TL ++V E G YTC A + G
Sbjct: 2272 NPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVG 2331
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+M + VV PA I + + + G+ + ++ +GEP PK
Sbjct: 2332 KDEMRVRVKVVT------APATIRNKTYLAVQVPYGDVVTVACEAKGEPMPK 2377
Score = 61.7 bits (143), Expect = 5e-08
Identities = 86/371 (23%), Positives = 138/371 (37%), Gaps = 60/371 (16%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVW------MKNGHEVEEEAGRMTSQFNGFDC-CLTIKD 3113
K+ G + C G P P + W + N +++G T ++ F+ L +
Sbjct: 2254 KVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNE 2313
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
+ + +EG Y+C A N GK R+ VVT A A ++ + V+ Y T+
Sbjct: 2314 VGMREEGDYTCFAENQVGKDEMRVRVKVVT------APATIRNKTYLAVQVPYGDVVTV- 2366
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
C+ G P PKV+W +V+ KYQ Q TL I
Sbjct: 2367 --------------ACEAKGEPMPKVTWLSPTNKVI-PTSSEKYQIYQDGTLLIQKAQRS 2411
Query: 3234 DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE----GDELRISA 3289
D G Y RN++G + V+ P+ P+ + E G I
Sbjct: 2412 DSGNYTCLVRNSAGEDRKTVWIHVN-----VQPPKINGNPNPITTVREIAAGGSRKLIDC 2466
Query: 3290 VVEAYPSVGVTW-YRDGVRL-RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
E P+ V W + +GV L P +T+ +G ++ + ++ D+ C A NE
Sbjct: 2467 KAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLD--IRSLRKSDSVQLVCMARNEG 2524
Query: 3348 GRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
G A ++ V+ EP P+ P A G T+ + C
Sbjct: 2525 GEARLIVQLTVL------EPMEKPIFHDP------------ISEKITAMAGHTISLNCSA 2566
Query: 3408 VGDPKPDVYWL 3418
G P P + W+
Sbjct: 2567 AGTPTPSLVWV 2577
Score = 58.8 bits (136), Expect = 3e-07
Identities = 49/172 (28%), Positives = 70/172 (40%), Gaps = 10/172 (5%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A GSR + C P V W + GV+L + V G +L++ + SDS +
Sbjct: 2456 AAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQ 2515
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENELVLECRIRGQPL 2722
C NE G L V E P F I + +A + + L C G P
Sbjct: 2516 LVCMARNEGGEARLIVQLTVLEPME----KPIFHDPISEKITAMAGHTISLNCSAAGTPT 2571
Query: 2723 PKITW-FKDDKQIPSDGRYQAFY-LADGVCRLAIDNPTPEDSGTYTCKAENS 2772
P + W + + S + Q FY ADG+ L I + D+G Y C A N+
Sbjct: 2572 PSLVWVLPNGTDLQSGQQLQRFYHKADGM--LHISGLSSVDAGAYRCVARNA 2621
Score = 58.0 bits (134), Expect = 6e-07
Identities = 74/317 (23%), Positives = 125/317 (39%), Gaps = 35/317 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEAGRMTSQF-NGF 3105
++P F D + ++ +AG T +L CS G P P +VW + NG ++ ++G+ +F +
Sbjct: 2540 EKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDL--QSGQQLQRFYHKA 2597
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
D L I ++ D G Y C A N G T+R V LK E
Sbjct: 2598 DGMLHISGLSSVDAGAYRCVARNAAGH----------TERLV-----SLKVGLKPEANKQ 2642
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSW-YKDGEEVVYDKRRNKYQDEQFHT 3224
Y ++ + ++L C G+ + SW +G + + + T
Sbjct: 2643 YHNLVSIINGE-------TLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGT 2695
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
L + ++ D G Y G ++V AY P P+ G+
Sbjct: 2696 LTVREASVFDRGTYVCRMETEYGPSVTSIPVIV----IAY-PPRITSEPTPVIYTRPGNT 2750
Query: 3285 LRISAVVEAYPSVGVTW-YRDGVRLRPSRRAIMTLDR--DGQIELALAAVTTRDAGVYTC 3341
++++ + P +TW D L+ +A + +R Q L + T RDAG Y C
Sbjct: 2751 VKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKC 2810
Query: 3342 TASNEVGRASTSGKVEV 3358
A N +G S + + V
Sbjct: 2811 MAKNILGSDSKTTYIHV 2827
Score = 53.6 bits (123), Expect = 1e-05
Identities = 78/310 (25%), Positives = 119/310 (38%), Gaps = 44/310 (14%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC-CLTIKDINIDDEG 3120
+ G+T + C KG P P + W+ V + + S+ + L+IK+ + D G
Sbjct: 1962 VYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRG 2021
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
Y C A+N G S RL V V + +E+ + PP ++ +
Sbjct: 2022 VYKCVASNAAGADSLAIRLHVAALPPV------IHQEKLENIS--LPPGLSIHIH----- 2068
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYK-DGEEVVYDK--RRNKYQDEQFHTLEIAPTNLDDGGV 3237
C +P P V W DG ++ + N + TL I D G
Sbjct: 2069 --------CTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPN-GTLYIRNLAPKDSGR 2119
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRISAVVEAYPS 3296
YE A N G+ V ++ A G P + G L++ P
Sbjct: 2120 YECVAANLVGSAR----RTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPW 2175
Query: 3297 VGVTWYRDGVRLRPSRRAIMTL-DRDGQIE------LALAAVTTRDAGVYTCTASNEVGR 3349
+ W RL PS+R I L D +I+ L + +VT +DAG Y C A N+VG
Sbjct: 2176 PRILW-----RL-PSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGD 2229
Query: 3350 ASTSGKVEVI 3359
KV+V+
Sbjct: 2230 DYVVLKVDVV 2239
Score = 53.2 bits (122), Expect = 2e-05
Identities = 87/365 (23%), Positives = 139/365 (38%), Gaps = 59/365 (16%)
Query: 3061 KILAGETANLT-CSVKGKPVPGVVW-MKNGHEVEEE--AGRMTSQFNGFDCCLTIKDINI 3116
+I AG + L C +G P P V+W G + R+T NG L I+ +
Sbjct: 2454 EIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNG---SLDIRSLRK 2510
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D + C A N G+A +L TV E K P F + +
Sbjct: 2511 SDSVQLVCMARNEGGEARLIVQL------TVLEPMEK--------------PIFHDPISE 2550
Query: 3177 R-RVQATYPVRLTCQVIGSPPPKVSW-YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+ A + + L C G+P P + W +G ++ ++ ++ + L I+ + D
Sbjct: 2551 KITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVD 2610
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y ARN +G H +V ++ + PE L + G+ L++
Sbjct: 2611 AGAYRCVARNAAG----HTERLV--SLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGA 2664
Query: 3295 PSVGVTW-YRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
+W +G+ L P ++L +G + + A+V D G Y C E G + T
Sbjct: 2665 GQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVF--DRGTYVCRMETEYGPSVT 2722
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
S V VI PP + S P R G+TV + C +G PK
Sbjct: 2723 SIPVIVIA--------YPPRITSEPTPV------------IYTRPGNTVKLNCMAMGIPK 2762
Query: 3413 PDVYW 3417
D+ W
Sbjct: 2763 ADITW 2767
Score = 53.2 bits (122), Expect = 2e-05
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 17/186 (9%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKY-RKKLVDGLITLEVLNAVPSDSAE 2663
+ G +KL C+ + +W NG+ L+ R L+D TL V A D
Sbjct: 2650 INGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNG-TLTVREASVFDRGT 2708
Query: 2664 YSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
Y C +E E G TS + V P + P P +TR N + L C G
Sbjct: 2709 YVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRP--------GNTVKLNCMAMGI 2760
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFY---LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P ITW DK G Y L I + T D+G Y C A+N + +D
Sbjct: 2761 PKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDS 2820
Query: 2778 ITHFVN 2783
T +++
Sbjct: 2821 KTTYIH 2826
Score = 49.2 bits (112), Expect = 3e-04
Identities = 48/196 (24%), Positives = 82/196 (41%), Gaps = 18/196 (9%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLIT--LEVLNAVP 2658
D+T +EG +L+C+V +S P++ W +G +L + L + L + + P
Sbjct: 488 DQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEP 547
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN---ELVLEC 2715
SDS Y C + + + VY S P+ + +DT + +N + L C
Sbjct: 548 SDSGLYQCIAQ-----VRDEMDRMVYRVLVQS---PSTQPAEKDTVTIGKNPGESVTLPC 599
Query: 2716 RIRGQPLPKITWFKDDKQIPSD--GRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P ++W +++I +D + L +G L+I DSG Y C A N
Sbjct: 600 NALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGT--LSIPKVQVSDSGYYRCVAVNQQ 657
Query: 2774 WTDQITHFVNFTGRES 2789
D T + T + S
Sbjct: 658 GADHFTVGITVTKKGS 673
Score = 46.8 bits (106), Expect = 0.001
Identities = 85/393 (21%), Positives = 137/393 (34%), Gaps = 53/393 (13%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE 3093
S++ + + V A P + + G T L CS G P P ++W + +
Sbjct: 2130 SARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMID 2189
Query: 3094 EAGRMTSQFNGF-DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
S+ F + L +K + D G Y C A N G D V + D
Sbjct: 2190 ALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVG-----------DDYVVLKVDV 2238
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
+K + E + D +V +++ C G P P++SW +V
Sbjct: 2239 VMKPAKIEHKEEN----------DHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSF 2288
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVY--EVTARNNSGAVSCHCGLVVDKG-----IRAYV 3265
++ D T N +G +Y EV R G +C V K ++
Sbjct: 2289 MQS--DDSGGRTKRYVVFN--NGTLYFNEVGMR-EEGDYTCFAENQVGKDEMRVRVKVVT 2343
Query: 3266 APEFCCGLEPL-YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI 3324
AP L ++ GD + ++ + P VTW ++ P+ + +DG
Sbjct: 2344 APATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDG-- 2401
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEP 3384
L + D+G YTC N G + + V P+I + P
Sbjct: 2402 TLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHV----NVQPPKI-----------NGNP 2446
Query: 3385 MFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
I R A G +I+C+ G P P V W
Sbjct: 2447 NPITTVREI-AAGGSRKLIDCKAEGIPTPRVLW 2478
Score = 46.0 bits (104), Expect = 0.002
Identities = 38/167 (22%), Positives = 68/167 (40%), Gaps = 8/167 (4%)
Query: 2615 CSVISSSDPTVTWYR--NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENEN 2672
C P VTW + G L+ + ++ V TL + D +Y CT N +
Sbjct: 1875 CEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDRGQYMCTASNLH 1934
Query: 2673 GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDK 2732
G L V + + I + + + T +L + + +EC +G P P+I+W D+
Sbjct: 1935 GLDRMVVLLSV--TVQQPQILASHYQDV--TVYLGDT-IAMECLAKGTPAPQISWIFPDR 1989
Query: 2733 QI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
++ + ++ L+I + D G Y C A N+ D +
Sbjct: 1990 RVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSL 2036
Score = 45.2 bits (102), Expect = 0.004
Identities = 59/257 (22%), Positives = 103/257 (40%), Gaps = 38/257 (14%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFK--DDKQIPSDGRYQAF-YLADGV 2749
P T+S + AE + V C G+P P +TW K + + R Q F L +G
Sbjct: 1853 PQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGT 1912
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L I +D G Y C A N D++ ++ T ++ Q+ +
Sbjct: 1913 --LVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILAS--------------- 1955
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYR--NARVFVEQG 2866
H+ D V G TI ++ +G P ++ W+ R V + +R+ + +
Sbjct: 1956 ----HY----QDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHEN 2007
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
TL++ + + ++ G+Y C A +A G + + V P VI ++I +
Sbjct: 2008 -RTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVA------ALPPVIHQEKLENISLP 2060
Query: 2927 VGEDINISFRTQGEPKP 2943
G I+I + P P
Sbjct: 2061 PGLSIHIHCTAKAAPLP 2077
Score = 42.7 bits (96), Expect = 0.022
Identities = 43/184 (23%), Positives = 74/184 (40%), Gaps = 16/184 (8%)
Query: 2593 KPVFSTFLTDR-TAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDN--KLKYRKKLVDGL 2648
KP+F ++++ TA+ G + L CS + P++ W NG L + +L+ DG+
Sbjct: 2541 KPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGM 2600
Query: 2649 ITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAE 2708
+ + L++V D+ Y C N G +LKV + P + + +
Sbjct: 2601 LHISGLSSV--DAGAYRCVARNAAGHTERLVSLKV-------GLKPEANKQYHNLVSIIN 2651
Query: 2709 NE-LVLECRIRGQPLPKITW-FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
E L L C G + +W + + L D L + + D GTY
Sbjct: 2652 GETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDN-GTLTVREASVFDRGTYV 2710
Query: 2767 CKAE 2770
C+ E
Sbjct: 2711 CRME 2714
Score = 40.7 bits (91), Expect = 0.090
Identities = 59/240 (24%), Positives = 93/240 (38%), Gaps = 43/240 (17%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVP 3080
+R RN G ++ S+ VGL +PE + I+ GET L C+ G
Sbjct: 2614 YRCVARNAAG---HTERLVSLKVGL---KPEANKQYHNLVSIINGETLKLPCTPPGAGQG 2667
Query: 3081 GVVW-MKNGHEVE--EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYA 3137
W + NG +E + GR++ NG LT+++ ++ D G Y C +G + T
Sbjct: 2668 RFSWTLPNGMHLEGPQTLGRVSLLDNG---TLTVREASVFDRGTYVCRMETEYGPSVTSI 2724
Query: 3138 RLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP---VRLTCQVIGS 3194
+ V+ YPP+ T V T P V+L C +G
Sbjct: 2725 PVIVIA----------------------YPPRITS--EPTPVIYTRPGNTVKLNCMAMGI 2760
Query: 3195 PPPKVSW-YKDGEEVVYDKRRNKYQDEQFH---TLEIAPTNLDDGGVYEVTARNNSGAVS 3250
P ++W D + + Y + H +L I D G Y+ A+N G+ S
Sbjct: 2761 PKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDS 2820
>AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific titin
protein.
Length = 926
Score = 83.0 bits (196), Expect = 2e-14
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F +++ G L+ +VI P + W+ NGVLL Y+ +L +
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEA------------------SPIPPT 2695
L D EY+C N+ G SA LK+ E P PP
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
F + ++ + E + G+P P +TWFK++KQ+ + Y + +G ++
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228
Query: 2756 NPTPEDSGTYTCKAEN 2771
+P EDSG Y CKAEN
Sbjct: 229 DPQREDSGLYICKAEN 244
Score = 73.7 bits (173), Expect = 1e-11
Identities = 54/200 (27%), Positives = 85/200 (42%), Gaps = 6/200 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I G+ A L+ +V G P P + W NG + A F+G D L I ++DEG
Sbjct: 60 ISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD-YKFVFDGDDHSLIILFTKLEDEGE 118
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE---GDYPPQFTMRLRDRR 3178
Y+C A+N +GK A L + + D + + + +E G PP F L+ R
Sbjct: 119 YTCMASNDYGKTICSAYLKI-NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR 177
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTLEIAPTNLDDGGV 3237
P V+G P P V+W+K+ +++ + T + +D G+
Sbjct: 178 CAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGL 237
Query: 3238 YEVTARNNSGAVSCHCGLVV 3257
Y A N G +C L+V
Sbjct: 238 YICKAENMLGESTCAAELLV 257
Score = 56.8 bits (131), Expect = 1e-06
Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD +S V P + W+ +GV L PS D D L + D G YTC
Sbjct: 63 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTC 121
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM---FIRKPRSSEAREG 3398
ASN+ G+ S +++ + + ++ + P F+++ + +G
Sbjct: 122 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 181
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
I E VVG+P P V W ++
Sbjct: 182 LPAIFEYTVVGEPAPTVTWFKE 203
Score = 56.0 bits (129), Expect = 2e-06
Identities = 59/266 (22%), Positives = 99/266 (37%), Gaps = 10/266 (3%)
Query: 2661 SAEYSCTVENENGAISTSANLKVYPS---FEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
SAE + NE + + VYP+ E P F + + + + L +
Sbjct: 15 SAELQLSKINET--LELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTV 72
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
G P PKI WF + + Y+ + D + + ED G YTC A N
Sbjct: 73 IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL-EDEGEYTCMASNDYGKTI 131
Query: 2778 ITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIR 2837
+ ++ + + + + PHF L + A+G + +
Sbjct: 132 CSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVV 191
Query: 2838 GCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P V W +E + + T VY + G T ++D +SGLY C+A + G
Sbjct: 192 GEPAPTVTWFKENKQLCTSVYYTI-IHNPNGSGTFIVNDPQREDSGLYICKAENMLGEST 250
Query: 2896 MNAAITV-VQPSDLDGKPAVIVGRPE 2920
A + V ++ +D+ P PE
Sbjct: 251 CAAELLVLLEDTDMTDTPCKAKSTPE 276
Score = 53.6 bits (123), Expect = 1e-05
Identities = 56/229 (24%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+E EG P F + + + L+ VIG P PK+ W+ +G + D
Sbjct: 42 SEKEGT-GPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 100
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--------DKGIRAYVA----- 3266
H+L I T L+D G Y A N+ G C L + D + VA
Sbjct: 101 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 160
Query: 3267 ------PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR 3320
P F L+P+ + +G V P+ VTW+++ +L S + +
Sbjct: 161 LGGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 219
Query: 3321 DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI--GTDQTSEP 3367
+G + D+G+Y C A N +G ++ + ++ V+ TD T P
Sbjct: 220 NGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 268
Score = 41.9 bits (94), Expect = 0.039
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+ T L D + EG V LT S+ ++ + V WY L+ + K++ TL +
Sbjct: 835 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 892
Query: 2654 LNAVPSD-SAEYSCTVENENGAISTSANLKV 2683
D EY C N++G +TSA L V
Sbjct: 893 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 923
Score = 39.1 bits (87), Expect = 0.28
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L ++ G A +V G+P P V W K ++
Sbjct: 167 PHFLKELK-PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 225
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
+ D +D G Y C+A N G+++ A L V+ + T D K + + E D+P
Sbjct: 226 IVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM-TDTPCKAKSTPEAPEDFP 282
Score = 36.7 bits (81), Expect = 1.5
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRD-AGVYTCTASNEVGRASTSGKVE 3357
V WY + +L PS L L + V T D G Y C A N+ G+ +TS K+
Sbjct: 864 VNWYFEN-KLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 922
Query: 3358 VI 3359
V+
Sbjct: 923 VV 924
Score = 35.5 bits (78), Expect = 3.4
Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 3109 LTIKDINIDD-EGRYSCEATNTHGKASTYARLAVV 3142
L I +N +D +G Y CEA N GK +T A+L VV
Sbjct: 890 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV 924
Score = 35.1 bits (77), Expect = 4.5
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD-GGVYEVTAR 3243
V LT + + +V+WY + + V D++ QD+ +TL I N +D G Y A
Sbjct: 852 VHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 909
Query: 3244 NNSGAVSCHCGLVVDK 3259
N+SG + L V K
Sbjct: 910 NDSGKTATSAKLTVVK 925
>AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.
Length = 1019
Score = 83.0 bits (196), Expect = 2e-14
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F +++ G L+ +VI P + W+ NGVLL Y+ +L +
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEA------------------SPIPPT 2695
L D EY+C N+ G SA LK+ E P PP
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 2696 FTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAID 2755
F + ++ + E + G+P P +TWFK++KQ+ + Y + +G ++
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228
Query: 2756 NPTPEDSGTYTCKAEN 2771
+P EDSG Y CKAEN
Sbjct: 229 DPQREDSGLYICKAEN 244
Score = 73.7 bits (173), Expect = 1e-11
Identities = 54/200 (27%), Positives = 85/200 (42%), Gaps = 6/200 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I G+ A L+ +V G P P + W NG + A F+G D L I ++DEG
Sbjct: 60 ISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD-YKFVFDGDDHSLIILFTKLEDEGE 118
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE---GDYPPQFTMRLRDRR 3178
Y+C A+N +GK A L + + D + + + +E G PP F L+ R
Sbjct: 119 YTCMASNDYGKTICSAYLKI-NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR 177
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTLEIAPTNLDDGGV 3237
P V+G P P V+W+K+ +++ + T + +D G+
Sbjct: 178 CAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGL 237
Query: 3238 YEVTARNNSGAVSCHCGLVV 3257
Y A N G +C L+V
Sbjct: 238 YICKAENMLGESTCAAELLV 257
Score = 60.9 bits (141), Expect = 8e-08
Identities = 52/176 (29%), Positives = 84/176 (47%), Gaps = 11/176 (6%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG-GVYEVTAR 3243
V LT + + +V+WY + + V D++ QD+ +TL I N +D G Y A
Sbjct: 852 VHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 909
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+SG + L V K RA AP +EPL ++ G + + +++ P+V W++
Sbjct: 910 NDSGKTATSAKLTVVK--RA--APVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFK 964
Query: 3304 DGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G + S + +I + +E+ V D G YTC ASNE G S + + V
Sbjct: 965 AGREIYESDKCSIRSSKYISSLEILRTQVV--DCGEYTCKASNEYGSVSCTATLTV 1018
Score = 59.3 bits (137), Expect = 2e-07
Identities = 50/180 (27%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+ T L D + EG V LT S+ ++ + V WY L+ + K++ TL +
Sbjct: 835 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 892
Query: 2654 LNAVPSD-SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF-HLAENEL 2711
D EY C N++G +TSA L V A+P+ + HLA+
Sbjct: 893 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK--RAAPVIKRKIEPLEVALGHLAK--- 947
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
C I+ P + WFK ++I + + + + L I D G YTCKA N
Sbjct: 948 -FTCEIQSAPNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKASN 1005
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 22/150 (14%)
Query: 3109 LTIKDINIDD-EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I +N +D +G Y CEA N GK +T A+L VV +R+A
Sbjct: 890 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV--------------KRAA------- 928
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P ++ V + + TC++ +P + W+K G E+ + + + +LEI
Sbjct: 929 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 988
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
T + D G Y A N G+VSC L V
Sbjct: 989 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018
Score = 56.8 bits (131), Expect = 1e-06
Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
GD +S V P + W+ +GV L PS D D L + D G YTC
Sbjct: 63 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTC 121
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM---FIRKPRSSEAREG 3398
ASN+ G+ S +++ + + ++ + P F+++ + +G
Sbjct: 122 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 181
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
I E VVG+P P V W ++
Sbjct: 182 LPAIFEYTVVGEPAPTVTWFKE 203
Score = 56.0 bits (129), Expect = 2e-06
Identities = 59/266 (22%), Positives = 99/266 (37%), Gaps = 10/266 (3%)
Query: 2661 SAEYSCTVENENGAISTSANLKVYPS---FEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
SAE + NE + + VYP+ E P F + + + + L +
Sbjct: 15 SAELQLSKINET--LELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTV 72
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
G P PKI WF + + Y+ + D + + ED G YTC A N
Sbjct: 73 IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL-EDEGEYTCMASNDYGKTI 131
Query: 2778 ITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIR 2837
+ ++ + + + + PHF L + A+G + +
Sbjct: 132 CSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVV 191
Query: 2838 GCPT-RVEWLREGRSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P V W +E + + T VY + G T ++D +SGLY C+A + G
Sbjct: 192 GEPAPTVTWFKENKQLCTSVYYTI-IHNPNGSGTFIVNDPQREDSGLYICKAENMLGEST 250
Query: 2896 MNAAITV-VQPSDLDGKPAVIVGRPE 2920
A + V ++ +D+ P PE
Sbjct: 251 CAAELLVLLEDTDMTDTPCKAKSTPE 276
Score = 53.6 bits (123), Expect = 1e-05
Identities = 56/229 (24%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+E EG P F + + + L+ VIG P PK+ W+ +G + D
Sbjct: 42 SEKEGT-GPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 100
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV--------DKGIRAYVA----- 3266
H+L I T L+D G Y A N+ G C L + D + VA
Sbjct: 101 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 160
Query: 3267 ------PEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR 3320
P F L+P+ + +G V P+ VTW+++ +L S + +
Sbjct: 161 LGGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 219
Query: 3321 DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI--GTDQTSEP 3367
+G + D+G+Y C A N +G ++ + ++ V+ TD T P
Sbjct: 220 NGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 268
Score = 47.2 bits (107), Expect = 0.001
Identities = 43/183 (23%), Positives = 75/183 (40%), Gaps = 31/183 (16%)
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED-SGTYTCKAENSVWTDQITHFV 2782
++ W+ ++K +PSD +++ L ID ED G Y C+A N
Sbjct: 863 EVNWYFENKLVPSDEKFKCLQ-DQNTYTLVIDKVNTEDHQGEYVCEALND---------- 911
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
S T+ K + +++ P + +VA G EI+ P
Sbjct: 912 ---------SGKTATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEIQSAPNV 958
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLY--TLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
R +W + GR E+Y + + + Y +L + + G YTC+A + +G+V A
Sbjct: 959 RFQWFKAGR---EIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 1015
Query: 2900 ITV 2902
+TV
Sbjct: 1016 LTV 1018
Score = 45.6 bits (103), Expect = 0.003
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L++ G A TC ++ P W K G E+ E+ + + + + + L I + D
Sbjct: 938 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCSIRSSKYISSLEILRTQVVDC 996
Query: 3120 GRYSCEATNTHGKASTYARLAV 3141
G Y+C+A+N +G S A L V
Sbjct: 997 GEYTCKASNEYGSVSCTATLTV 1018
Score = 43.6 bits (98), Expect = 0.013
Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 2/107 (1%)
Query: 2577 RSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN 2636
++ S K T+ + + PV + G K TC + S+ + W++ G +
Sbjct: 914 KTATSAKLTVVKRAA--PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE 971
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
K + + +LE+L D EY+C NE G++S +A L V
Sbjct: 972 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018
Score = 39.1 bits (87), Expect = 0.28
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L ++ G A +V G+P P V W K ++
Sbjct: 167 PHFLKELK-PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 225
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
+ D +D G Y C+A N G+++ A L V+ + T D K + + E D+P
Sbjct: 226 IVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM-TDTPCKAKSTPEAPEDFP 282
Score = 36.7 bits (81), Expect = 1.5
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRD-AGVYTCTASNEVGRASTSGKVE 3357
V WY + +L PS L L + V T D G Y C A N+ G+ +TS K+
Sbjct: 864 VNWYFEN-KLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 922
Query: 3358 VI 3359
V+
Sbjct: 923 VV 924
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 82.6 bits (195), Expect = 2e-14
Identities = 91/357 (25%), Positives = 151/357 (42%), Gaps = 44/357 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R ++ L+ L ++ P+DS EYSC
Sbjct: 2842 EGQTLDLKCVVPGQAHAQVTWHKRG----GNLPARHQVHGPLLRLNQVS--PADSGEYSC 2895
Query: 2667 TVENENGAISTSANLKVYPSFEASPIP-PTFTRSI---RDTFHLAENE-LVLECRIRGQP 2721
V +G + S + + PS PIP P + I + H+ E + L L C + GQ
Sbjct: 2896 QVTGSSGTLEASVLVTIEPS-SPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQA 2954
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
++TW+K +P+ R+Q +L + + +P DSG Y C+A +Q F
Sbjct: 2955 HAQVTWYKRGGSLPA--RHQTH-----GSQLRLHHVSPADSGEYVCRAAGGPGPEQEASF 3007
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V P+ ++ + R S++ P V Q + + + P
Sbjct: 3008 T------VTVPPSEGSSYRLRSPVISID---PPSSTV----QQGQDASFKCLIHDGAAPI 3054
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+EW + E+ N + + T+ + G Y C A +A+G A +
Sbjct: 3055 SLEWKTRNQ---ELEDNVHISPNGSIITIV--GTRPSNHGTYRCVASNAYG-----VAQS 3104
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
VV S + G P V V PE + + VG+ + + + GEP+ A RI P ++
Sbjct: 3105 VVNLS-VHGPPTVSV-LPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLE 3159
Score = 81.8 bits (193), Expect = 4e-14
Identities = 98/366 (26%), Positives = 133/366 (36%), Gaps = 49/366 (13%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V I P QL + G+ A CS G P P + W G++ ++ L +
Sbjct: 1870 VSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGG------PGGQLPAKAQIHGGILRLP 1923
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D+ +Y C A H A AV+ V G P+ +
Sbjct: 1924 AVEPTDQAQYLCRA---HSSAGQQVARAVL------------------HVHGGGGPRVQV 1962
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+V A VRL C+ G P ++W K+G + R + TL I
Sbjct: 1963 SPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSER---TDIATLLIPAITT 2019
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A + +G +VV A P P + EG L ++ VV
Sbjct: 2020 ADAGFYLCVATSPAGTAQARIQVVVLSASDASQPPVKIESSSP--SVTEGQTLDLNCVVA 2077
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
VTWYR G L P + G L L V+ D+G Y C N G
Sbjct: 2078 GSAHAQVTWYRRGGSL-PHHTQV-----HGS-RLRLPQVSPADSGEYVCRVENGSGPKEA 2130
Query: 3353 SGKVEVI-GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S V V+ GT S P P VP S P+ I +P SS EG T+ + C V G
Sbjct: 2131 SITVSVLHGTH--SGPSYTP------VPGSTRPIRI-EPSSSHVAEGQTLDLNCVVPGQA 2181
Query: 3412 KPDVYW 3417
V W
Sbjct: 2182 HAQVTW 2187
Score = 80.6 bits (190), Expect = 9e-14
Identities = 86/321 (26%), Positives = 133/321 (41%), Gaps = 39/321 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T VEG + L C V +TWY+ G L R + + L ++ +DS E
Sbjct: 2642 TVVEGQTLDLNCVVARQPQAIITWYKRG----GSLPSRHQTHGSHLRLHQMSV--ADSGE 2695
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---DTFHLAENE-LVLECRIRG 2719
Y C N A+ S + V PS SP P + IR + H+AE E L L C + G
Sbjct: 2696 YVCRANNNIDALEASIVISVSPS-AGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2754
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
Q ++TW K +PS ++ G RL + + +P DSG Y C+ S + +
Sbjct: 2755 QAHAQVTWHKRGGSLPS------YHQTRG-SRLRLHHVSPADSGEYVCRVMGSSGPLEAS 2807
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V S I + SR VA G T+ L+ + G
Sbjct: 2808 VLVTIEASGSSAVHVPAPGGAPPIRIEPSSSR------------VAEGQTLDLKCVVPGQ 2855
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G ++ AR V L L L+ V+ +SG Y+C+ + G ++ +
Sbjct: 2856 AHAQVTWHKRGGNLP-----ARHQVHGPL--LRLNQVSPADSGEYSCQVTGSSGTLEASV 2908
Query: 2899 AITVVQPSDLDGKPAVIVGRP 2919
+T ++PS PA + +P
Sbjct: 2909 LVT-IEPSSPGPIPAPGLAQP 2928
Score = 77.4 bits (182), Expect = 9e-13
Identities = 91/358 (25%), Positives = 133/358 (37%), Gaps = 60/358 (16%)
Query: 3065 GETANLTCSVKGK-PVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G C+ K K P +VW + + G++ ++ F+ LTI+++ + D G Y
Sbjct: 1788 GADVTFICTAKSKSPAYTLVWTRLHN------GKLPTRAMDFNGILTIRNVQLSDAGTYV 1841
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C +N A L V T+ SA V +PPQ T VQ
Sbjct: 1842 CTGSNMFAMDQGTATLHVQASGTL-----------SAPVVSIHPPQLT-------VQPGQ 1883
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C GSP P + W G + + + PT D Y A
Sbjct: 1884 LAEFRCSATGSPTPTLEW--TGGPGGQLPAKAQIHGGILRLPAVEPT---DQAQYLCRAH 1938
Query: 3244 NNSGAVSCHCGLVV--DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+++G L V G R V+PE ++H G +R+ PS +TW
Sbjct: 1939 SSAGQQVARAVLHVHGGGGPRVQVSPE-------RTQVHAGRTVRLYCRAAGVPSATITW 1991
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++G L P R+ +R L + A+TT DAG Y C A++ G A +V V+
Sbjct: 1992 RKEGGSLPPQARS----ERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSA 2047
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
S+ PPV I P EG T+ + C V G V W R
Sbjct: 2048 SDASQ---PPVKIESSSP--------------SVTEGQTLDLNCVVAGSAHAQVTWYR 2088
Score = 77.0 bits (181), Expect = 1e-12
Identities = 91/356 (25%), Positives = 144/356 (40%), Gaps = 46/356 (12%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTA--VEGSRVKLTCSVISSSDPTVTW 2627
S EA +++ ++ LS + ++ + + +A G + L C V S + T+TW
Sbjct: 2510 SSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITW 2569
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
Y+ G L R ++V L + P+DS EY C V N G+ TS + + S
Sbjct: 2570 YKRG----GSLPSRHQIVGS--RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG 2623
Query: 2688 EASP---IPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+ PP S T + L L C + QP ITW+K +PS R+Q
Sbjct: 2624 SSHVPRVSPPIRIESSSPTV-VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RHQTHG 2680
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
L + + DSG Y C+A N++ D + + + S SP+ +
Sbjct: 2681 -----SHLRLHQMSVADSGEYVCRANNNI--DALEASIVISVSPSAGSPSAPGSSMP--- 2730
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFV 2863
+ES H VA G T+ L + G +V W + G S+ Y R
Sbjct: 2731 -IRIESSSSH---------VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPS-YHQTRG-- 2777
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP 2919
L L V+ +SG Y CR + G ++ + +T+ + G AV V P
Sbjct: 2778 ----SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI----EASGSSAVHVPAP 2825
Score = 74.9 bits (176), Expect = 5e-12
Identities = 78/298 (26%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R + L+ L P+DS EY C
Sbjct: 2167 EGQTLDLNCVVPGQAHAQVTWHKRG----GSLPARHQTHGSLLRLH--QVTPADSGEYVC 2220
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKI 2725
V +G + S + + S PIPP S T +AE + L L C + GQ ++
Sbjct: 2221 HVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSST--VAEGQTLDLSCVVAGQAHAQV 2278
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
TW+K +P+ R+Q RL I +P D+G Y C+A N
Sbjct: 2279 TWYKRGGSLPA--RHQV-----RGSRLYIFQASPADAGQYVCRASN-------------- 2317
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVE 2844
G E+ ++ V + +A + S +P + QVA G T+ L + G +V
Sbjct: 2318 GMEASITVTVTGTQGANLAYPA-GSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT 2375
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
W + G S+ ++ G L L + +SG Y CR + ++ + +T+
Sbjct: 2376 WHKRGGSLPVRHQT------HG-SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2426
Score = 71.7 bits (168), Expect = 4e-11
Identities = 90/327 (27%), Positives = 137/327 (41%), Gaps = 56/327 (17%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
LS + +P + + EG + L C V S+ VTWYR G L + + V
Sbjct: 2045 LSASDASQPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPHHTQ-----V 2099
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASP--IP-PTFTRSIR- 2701
G L + P+DS EY C VEN +G S + V + P P P TR IR
Sbjct: 2100 HG-SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRI 2158
Query: 2702 --DTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPT 2758
+ H+AE + L L C + GQ ++TW K +P+ R+Q L + T
Sbjct: 2159 EPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RHQTH-----GSLLRLHQVT 2211
Query: 2759 PEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
P DSG Y C + + + V E+ V P + + +ES
Sbjct: 2212 PADSGEYVCHVVGTSGPLEASVLVTI---EASVIPGPIPPVR-------IES-------- 2253
Query: 2819 LTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVY--RNARVFVEQGLYTLALSDV 2875
+ VA G T+ L + G +V W + G S+ + R +R+++ Q
Sbjct: 2254 -SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ---------A 2303
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITV 2902
+ ++G Y CRA ++G M A+ITV
Sbjct: 2304 SPADAGQYVCRA--SNG---MEASITV 2325
Score = 68.9 bits (161), Expect = 3e-10
Identities = 85/311 (27%), Positives = 119/311 (38%), Gaps = 43/311 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R + V G L +L P+DS EY C
Sbjct: 2452 EGQTLDLNCLVAGQAHAQVTWHKRG----GSLPARHQ-VHGS-RLRLLQVTPADSGEYVC 2505
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTF--TRSIRDTFHLAENE-LVLECRIRGQPLP 2723
V +G S + + S R + LA L L C + Q
Sbjct: 2506 RVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPH 2565
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
ITW+K +PS R+Q RL I TP DSG Y C N + + + V
Sbjct: 2566 TITWYKRGGSLPS--RHQIVG-----SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVT 2618
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTR- 2842
G S P V + RI ES P V G T+ L + P
Sbjct: 2619 IQGSGSSHVPRV--SPPIRI-----ESSSP---------TVVEGQTLDLNCVVARQPQAI 2662
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + G S+ ++ G + L L ++ +SG Y CR A+ N+D A V
Sbjct: 2663 ITWYKRGGSLPSRHQT------HGSH-LRLHQMSVADSGEYVCR---ANNNIDALEASIV 2712
Query: 2903 VQPSDLDGKPA 2913
+ S G P+
Sbjct: 2713 ISVSPSAGSPS 2723
Score = 68.5 bits (160), Expect = 4e-10
Identities = 78/300 (26%), Positives = 119/300 (39%), Gaps = 40/300 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V S VTW++ G L R + L+ L A P+DS EY C
Sbjct: 2356 EGQTLDLNCVVPGQSHAQVTWHKRG----GSLPVRHQTHGSLLRL--YQASPADSGEYVC 2409
Query: 2667 TVENENGAISTSANLKVYP--SFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP 2723
V + + S + + P S A + PT R + +AE + L L C + GQ
Sbjct: 2410 RVLGSSVPLEASVLVTIEPAGSVPALGVTPT-VRIESSSSQVAEGQTLDLNCLVAGQAHA 2468
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW K +P+ R+Q RL + TP DSG Y C+ S T + + V
Sbjct: 2469 QVTWHKRGGSLPA--RHQVH-----GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVT 2521
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTR 2842
R S S + A RI S +A G T+ L + P
Sbjct: 2522 IQQRLSG-SHSQGVAYPVRIESSSA--------------SLANGHTLDLNCLVASQAPHT 2566
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + G S+ ++ L + VT +SG Y C + G+ + + +T+
Sbjct: 2567 ITWYKRGGSLPSRHQIVG-------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTI 2619
Score = 66.5 bits (155), Expect = 2e-09
Identities = 87/374 (23%), Positives = 137/374 (36%), Gaps = 58/374 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V + P + ++ AG T L C G P + W K G + +A + L I
Sbjct: 1960 VQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDI----ATLLIP 2015
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
I D G Y C AT+ G A ++ V++ + K++ + EG
Sbjct: 2016 AITTADAGFYLCVATSPAGTAQARIQVVVLSASDASQPPVKIESSSPSVTEGQ------- 2068
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+ L C V GS +V+WY+ G + + + + +++P
Sbjct: 2069 -----------TLDLNCVVAGSAHAQVTWYRRGGSLPH---HTQVHGSRLRLPQVSPA-- 2112
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG------LEPLYK-LHEGDEL 3285
D G Y N SG + V G + + G +EP + EG L
Sbjct: 2113 -DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTL 2171
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
++ VV VTW++ G L P+R G + L L VT D+G Y C
Sbjct: 2172 DLNCVVPGQAHAQVTWHKRGGSL-PARH-----QTHGSL-LRLHQVTPADSGEYVC---- 2220
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIEC 3405
V+GT E + + + +P P+ I + SS EG T+ + C
Sbjct: 2221 -----------HVVGTSGPLEASVLVTIEASVIPGPIPPVRI-ESSSSTVAEGQTLDLSC 2268
Query: 3406 EVVGDPKPDVYWLR 3419
V G V W +
Sbjct: 2269 VVAGQAHAQVTWYK 2282
Score = 62.5 bits (145), Expect = 3e-08
Identities = 83/342 (24%), Positives = 133/342 (38%), Gaps = 36/342 (10%)
Query: 2602 DRTAVEGSR-VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+RT V R V+L C T+TW + G L + R + D + TL + +D
Sbjct: 1965 ERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQA--RSERTD-IATLLIPAITTAD 2021
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C + G + V + +AS PP S + + L L C + G
Sbjct: 2022 AGFYLCVATSPAGTAQARIQVVVLSASDASQ-PPVKIESSSPSVTEGQT-LDLNCVVAGS 2079
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
++TW++ +P + RL + +P DSG Y C+ EN + +
Sbjct: 2080 AHAQVTWYRRGGSLPHHTQVHG-------SRLRLPQVSPADSGEYVCRVENGSGPKEASI 2132
Query: 2781 FVN-FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V+ G S S V TR R +E H VA G T+ L + G
Sbjct: 2133 TVSVLHGTHSGPSYTPVPG-STRPIR--IEPSSSH---------VAEGQTLDLNCVVPGQ 2180
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G S+ AR L L L VT +SG Y C G ++ +
Sbjct: 2181 AHAQVTWHKRGGSLP-----ARHQTHGSL--LRLHQVTPADSGEYVCHVVGTSGPLEASV 2233
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
+T ++ S + G P V ++ G+ +++S G+
Sbjct: 2234 LVT-IEASVIPG-PIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2273
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/310 (27%), Positives = 121/310 (39%), Gaps = 51/310 (16%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG + L+C V + VTWY+ G L + + R L + A P+D+ +
Sbjct: 2257 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGS------RLYIFQASPADAGQ 2310
Query: 2664 YSCTVENENGAIST-------SANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLEC 2715
Y C N A T ANL YP+ PI R + +AE + L L C
Sbjct: 2311 YVCRASNGMEASITVTVTGTQGANL-AYPAGSTQPI-----RIEPSSSQVAEGQTLDLNC 2364
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ GQ ++TW K +P R+Q + RL +P DSG Y C+ S +
Sbjct: 2365 VVPGQSHAQVTWHKRGGSLPV--RHQTH---GSLLRLY--QASPADSGEYVCRVLGS--S 2415
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ V T + P + RI S QVA G T+ L
Sbjct: 2416 VPLEASVLVTIEPAGSVPALGVTPTVRIESSS--------------SQVAEGQTLDLNCL 2461
Query: 2836 IRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
+ G +V W + G S+ AR V L L VT +SG Y CR + G
Sbjct: 2462 VAGQAHAQVTWHKRGGSLP-----ARHQVHGS--RLRLLQVTPADSGEYVCRVVGSSGTQ 2514
Query: 2895 DMNAAITVVQ 2904
+ + +T+ Q
Sbjct: 2515 EASVLVTIQQ 2524
Score = 61.7 bits (143), Expect = 5e-08
Identities = 83/372 (22%), Positives = 135/372 (36%), Gaps = 54/372 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P ++ G+T +L C V G+ V W K G G + + L +
Sbjct: 2345 IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG-------GSLPVRHQTHGSLLRLY 2397
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG-DYPPQFT 3171
+ D G Y C V+ EA + E + V P
Sbjct: 2398 QASPADSGEYVCR---------------VLGSSVPLEASVLVTIEPAGSVPALGVTPTVR 2442
Query: 3172 MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
+ +V + L C V G +V+W+K G + R++ + L++ P
Sbjct: 2443 IESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL---PARHQVHGSRLRLLQVTPA- 2498
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRIS 3288
D G Y +SG + + + + + + L G L ++
Sbjct: 2499 --DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLN 2556
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+V + +TWY+ G L PSR I+ G L + VT D+G Y C SN G
Sbjct: 2557 CLVASQAPHTITWYKRGGSL-PSRHQIV-----GS-RLRIPQVTPADSGEYVCHVSNGAG 2609
Query: 3349 RASTSGKVEVIGTDQTSEPRI-PPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
TS V + G+ + PR+ PP+ I S P + EG T+ + C V
Sbjct: 2610 SRETSLIVTIQGSGSSHVPRVSPPIRIE-----SSSPTVV---------EGQTLDLNCVV 2655
Query: 3408 VGDPKPDVYWLR 3419
P+ + W +
Sbjct: 2656 ARQPQAIITWYK 2667
Score = 61.3 bits (142), Expect = 6e-08
Identities = 81/364 (22%), Positives = 133/364 (36%), Gaps = 50/364 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ G+T +L C V +P + W K G G + S+ L + +++ D G
Sbjct: 2643 VVEGQTLDLNCVVARQPQAIITWYKRG-------GSLPSRHQTHGSHLRLHQMSVADSGE 2695
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A N ++V S G P + V
Sbjct: 2696 YVCRANNNIDALEASIVISVSPSAG------------SPSAPGSSMP-IRIESSSSHVAE 2742
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + Y + L + + D G Y
Sbjct: 2743 GETLDLNCVVPGQAHAQVTWHKRGGSLP------SYHQTRGSRLRLHHVSPADSGEYVCR 2796
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY------KLHEGDELRISAVVEAYP 3295
+SG + + ++ + V G P+ ++ EG L + VV
Sbjct: 2797 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQA 2856
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
VTW++ G L P+R + G + L L V+ D+G Y+C + G S
Sbjct: 2857 HAQVTWHKRGGNL-PARHQV-----HGPL-LRLNQVSPADSGEYSCQVTGSSGTLEASVL 2909
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T EP P + +P + +P++I + SS EG T+ + C V G V
Sbjct: 2910 V-------TIEPSSPGPIPAPGLA---QPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQV 2958
Query: 3416 YWLR 3419
W +
Sbjct: 2959 TWYK 2962
Score = 60.5 bits (140), Expect = 1e-07
Identities = 87/356 (24%), Positives = 128/356 (35%), Gaps = 46/356 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G T +L C V + + W K G G + S+ L I + D G Y C
Sbjct: 2550 GHTLDLNCLVASQAPHTITWYKRG-------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2602
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+N G T +VT ++ S+ V PP + V
Sbjct: 2603 HVSNGAGSRETSL---IVT----------IQGSGSSHVPRVSPP-IRIESSSPTVVEGQT 2648
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ L C V P ++WYK G + +++Q H L + ++ D G Y A N
Sbjct: 2649 LDLNCVVARQPQAIITWYKRGGSLP-----SRHQTHGSH-LRLHQMSVADSGEYVCRANN 2702
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRISAVVEAYPSVGVTW 3301
N A+ + V + AP + + EG+ L ++ VV VTW
Sbjct: 2703 NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTW 2762
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++ G L PS G L L V+ D+G Y C G S V I
Sbjct: 2763 HKRGGSL-PSYHQTR-----GS-RLRLHHVSPADSGEYVCRVMGSSGPLEASVLV-TIEA 2814
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+S +P P P+ I +P SS EG T+ ++C V G V W
Sbjct: 2815 SGSSAVHVP-------APGGAPPIRI-EPSSSRVAEGQTLDLKCVVPGQAHAQVTW 2862
Score = 58.0 bits (134), Expect = 6e-07
Identities = 75/322 (23%), Positives = 116/322 (36%), Gaps = 36/322 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+ P + +P + AGET L C G P W + G + GR T++
Sbjct: 3298 ESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLP---GRATARNE---- 3350
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L + +D GRY C TN G A +A+L V + S
Sbjct: 3351 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLV-------QGPPGSLPATSIPAGSTPT 3403
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
Q T +L + + A+ V C V ++ W+K+G ++ + QD L I
Sbjct: 3404 VQVTPQLETKSIGAS--VEFHCAVPSDRGTQLRWFKEGGQL---PPGHSVQD---GVLRI 3455
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE-PLYKLHEGDELR 3286
+ G Y A G LV+ P + + + G +
Sbjct: 3456 QNLDQSCQGTYICQAHGPWGKAQASAQLVIQ------ALPSVLINIRTSVQTVVVGHAVE 3509
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ P VTW + G LRP + + G + + +A V DAG Y CTA+N
Sbjct: 3510 FECLALGDPKPQVTWSKVGGHLRPG------IVQSGGV-VRIAHVELADAGQYRCTATNA 3562
Query: 3347 VGRASTSGKVEVIGTDQTSEPR 3368
G + + V Q S P+
Sbjct: 3563 AGTTQSHVLLLVQALPQISMPQ 3584
Score = 57.6 bits (133), Expect = 7e-07
Identities = 75/327 (22%), Positives = 118/327 (36%), Gaps = 40/327 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET +L C V G+ V W K G G + S L + ++ D G
Sbjct: 2740 VAEGETLDLNCVVPGQAHAQVTWHKRG-------GSLPSYHQTRGSRLRLHHVSPADSGE 2792
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C + G + + +A G PP + RV
Sbjct: 2793 YVCRVMGSSGPLEASVLVTI---------EASGSSAVHVPAPGGAPP-IRIEPSSSRVAE 2842
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ +++P D G Y
Sbjct: 2843 GQTLDLKCVVPGQAHAQVTWHKRGGNL---PARHQVHGPLLRLNQVSPA---DSGEYSCQ 2896
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLY------KLHEGDELRISAVVEAY 3294
+SG + + ++ + AP +P+Y + EG L ++ VV
Sbjct: 2897 VTGSSGTLEASVLVTIEPSSPGPIPAPGLA---QPIYIEASSSHVTEGQTLDLNCVVPGQ 2953
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
VTWY+ G L P+R G +L L V+ D+G Y C A+ G +
Sbjct: 2954 AHAQVTWYKRGGSL-PARH-----QTHGS-QLRLHHVSPADSGEYVCRAAGGPGPEQEAS 3006
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ + S R+ VIS D P S
Sbjct: 3007 FTVTVPPSEGSSYRLRSPVISIDPPSS 3033
Score = 57.6 bits (133), Expect = 7e-07
Identities = 73/313 (23%), Positives = 114/313 (36%), Gaps = 50/313 (15%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF 3105
AG P V + P G + C+V + W K G G++ +
Sbjct: 3398 AGSTPT-VQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEG-------GQLPPGHSVQ 3449
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
D L I++++ +G Y C+A GKA A+L + +V
Sbjct: 3450 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL----------------- 3492
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
+R + V + V C +G P P+V+W K G + R Q +
Sbjct: 3493 ----INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL----RPGIVQSGG--VV 3542
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
IA L D G Y TA N +G H L+V P+ E ++ G
Sbjct: 3543 RIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ------ALPQISMPQE--VRVPAGSAA 3594
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ YP+ ++W + L P R + L L +V +DAG Y CTA+N
Sbjct: 3595 VFPCIASGYPTPDISWSKLDGSLPPDSRLENNM-------LMLPSVQPQDAGTYVCTATN 3647
Query: 3346 EVGRASTSGKVEV 3358
G+ ++V
Sbjct: 3648 RQGKVKAFAHLQV 3660
Score = 57.2 bits (132), Expect = 1e-06
Identities = 84/356 (23%), Positives = 130/356 (36%), Gaps = 43/356 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G V W + G + +Q +G L + ++ D G
Sbjct: 2064 VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPHH-----TQVHGSR--LRLPQVSPADSGE 2116
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C N G ++V+ V G P + V
Sbjct: 2117 YVCRVENGSGPKEASITVSVL--------HGTHSGPSYTPVPGSTRP-IRIEPSSSHVAE 2167
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ ++ P D G Y
Sbjct: 2168 GQTLDLNCVVPGQAHAQVTWHKRGGSL---PARHQTHGSLLRLHQVTPA---DSGEYVCH 2221
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
SG + + ++ + P + EG L +S VV VTW
Sbjct: 2222 VVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSS-TVAEGQTLDLSCVVAGQAHAQVTW 2280
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
Y+ G L P+R + R ++ + A+ DAG Y C ASN + + T V V GT
Sbjct: 2281 YKRGGSL-PARHQV----RGSRLYIFQASPA--DAGQYVCRASNGMEASIT---VTVTGT 2330
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
Q + P S +P+ I +P SS+ EG T+ + C V G V W
Sbjct: 2331 -QGANLAYPAG--------STQPIRI-EPSSSQVAEGQTLDLNCVVPGQSHAQVTW 2376
Score = 56.8 bits (131), Expect = 1e-06
Identities = 74/311 (23%), Positives = 115/311 (36%), Gaps = 42/311 (13%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S T G + CS S PT+ W +L + ++ G++ L
Sbjct: 1868 PVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGP---GGQLPAKAQIHGGILRLPA 1924
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ P+D A+Y C + G A L V+ P R H A + L
Sbjct: 1925 VE--PTDQAQYLCRAHSSAGQQVARAVLHVH----GGGGPRVQVSPERTQVH-AGRTVRL 1977
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
CR G P ITW K+ +P R + + L I T D+G Y C A +
Sbjct: 1978 YCRAAGVPSATITWRKEGGSLPPQARSE----RTDIATLLIPAITTADAGFYLCVATSPA 2033
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
T Q +++ V++A +ES P V G T+ L
Sbjct: 2034 GTAQ-----------ARIQVVVLSASDASQPPVKIESSSP---------SVTEGQTLDLN 2073
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G +V W R G S+ + +V + L L V+ +SG Y CR + G
Sbjct: 2074 CVVAGSAHAQVTWYRRGGSLP---HHTQVHGSR----LRLPQVSPADSGEYVCRVENGSG 2126
Query: 2893 NVDMNAAITVV 2903
+ + ++V+
Sbjct: 2127 PKEASITVSVL 2137
Score = 56.4 bits (130), Expect = 2e-06
Identities = 87/368 (23%), Positives = 138/368 (37%), Gaps = 54/368 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P + G+T +L C V G+ V W K G G + ++ L +
Sbjct: 2156 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRG-------GSLPARHQTHGSLLRLH 2208
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D G Y C T G A + V + +V + G PP +
Sbjct: 2209 QVTPADSGEYVCHVVGTSGPLE--ASVLVTIEASV--------------IPGPIPP-VRI 2251
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L+C V G +V+WYK G + R++ + + + + +P
Sbjct: 2252 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL---PARHQVRGSRLYIFQASPA-- 2306
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIR-AYVAPEFC-CGLEPLY-KLHEGDELRISA 3289
D G Y A N A S + +G AY A +EP ++ EG L ++
Sbjct: 2307 -DAGQYVCRASNGMEA-SITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 2364
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTW++ G L P R G + L L + D+G Y C V
Sbjct: 2365 VVPGQSHAQVTWHKRGGSL-PVRH-----QTHGSL-LRLYQASPADSGEYVC----RVLG 2413
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+S + V+ T + + +P + ++P V SS+ EG T+ + C V G
Sbjct: 2414 SSVPLEASVLVTIEPAGS-VPALGVTPTVRIESS--------SSQVAEGQTLDLNCLVAG 2464
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2465 QAHAQVTW 2472
Score = 56.4 bits (130), Expect = 2e-06
Identities = 72/319 (22%), Positives = 116/319 (36%), Gaps = 45/319 (14%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
R PV S T +G C + + P ++ W L++ + +IT
Sbjct: 3022 RSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPN--GSIIT 3079
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAE 2708
++ PS+ Y C N G + NL V+ P+ P P + +
Sbjct: 3080 --IVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--------VG 3129
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ LEC G+P W + P+ + + L D L I + P D+GTY C
Sbjct: 3130 KAVTLECVSAGEPRSSARWTRISST-PAKLEQRTYGLMDSHTVLQISSAKPSDAGTYVCL 3188
Query: 2769 AENSVWTDQ-ITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
A+N++ T Q + TG + +P V E + V G
Sbjct: 3189 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE--------------------AELTVEAG 3228
Query: 2828 GTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCR 2886
T L+ G P R + W + + +R +E TL + V + +SG Y C
Sbjct: 3229 HTATLRCSATGSPARTIHWSKLRSPLPWQHR-----LEGD--TLIIPRVAQQDSGQYICN 3281
Query: 2887 AWSAHGNVDMNAAITVVQP 2905
A S G+ + + V P
Sbjct: 3282 ATSPAGHAEATIILHVESP 3300
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 21/184 (11%)
Query: 2594 PVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P ++T + + +V+ G V+L C + T W R G L + R +L L
Sbjct: 3300 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LH 3353
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
A P DS Y C V N+ G+ A L V S A+ IP T +++ T L
Sbjct: 3354 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3413
Query: 2710 EL----VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ C + ++ WFK+ Q+P Q DGV R I N GTY
Sbjct: 3414 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQ-----DGVLR--IQNLDQSCQGTY 3466
Query: 2766 TCKA 2769
C+A
Sbjct: 3467 ICQA 3470
Score = 54.8 bits (126), Expect = 5e-06
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 21/169 (12%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+T V G V+ C + P VTW + G L R +V + + + +D+
Sbjct: 3500 QTVVVGHAVEFECLALGDPKPQVTWSKVGGHL------RPGIVQSGGVVRIAHVELADAG 3553
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y CT N G + L V +A P + + +R A + V C G P
Sbjct: 3554 QYRCTATNAAGTTQSHVLLLV----QALP-QISMPQEVRVP---AGSAAVFPCIASGYPT 3605
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
P I+W K D +P D R L + + L + + P+D+GTY C A N
Sbjct: 3606 PDISWSKLDGSLPPDSR-----LENNM--LMLPSVQPQDAGTYVCTATN 3647
Score = 53.6 bits (123), Expect = 1e-05
Identities = 89/401 (22%), Positives = 133/401 (33%), Gaps = 54/401 (13%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKILAGETANLTCSVKGKPV 3079
+R N YG +S V L+ P V +LP G + + G+ L C G+P
Sbjct: 3091 YRCVASNAYGVAQSV-------VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPR 3143
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
W + + + T L I D G Y C A N G A +
Sbjct: 3144 SSARWTRIS-STPAKLEQRTYGLMDSHTVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3202
Query: 3140 AVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKV 3199
V T A G PQ + V+A + L C GSP +
Sbjct: 3203 IVDT---------------GAMAPG--APQVQAEEAELTVEAGHTATLRCSATGSPARTI 3245
Query: 3200 SWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK 3259
W K + + R + TL I D G Y A + +G L V+
Sbjct: 3246 HWSKLRSPLPWQHRL------EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVES 3299
Query: 3260 GIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD 3319
A PE + G+ +++ + P + W R G L P R
Sbjct: 3300 PPYATTVPEHA-------SVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATA---- 3347
Query: 3320 RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVP 3379
R+ + AA D+G Y C +N+VG A ++ V G P + + +P
Sbjct: 3348 RNELLHFERAA--PEDSGRYRCRVTNKVGSAEAFAQLLVQGP--------PGSLPATSIP 3397
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+ G +V C V D + W ++
Sbjct: 3398 AGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKE 3438
Score = 50.8 bits (116), Expect = 8e-05
Identities = 84/358 (23%), Positives = 124/358 (34%), Gaps = 50/358 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G+ V W K G G + ++ L + ++ D G
Sbjct: 2938 VTEGQTLDLNCVVPGQAHAQVTWYKRG-------GSLPARHQTHGSQLRLHHVSPADSGE 2990
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A G A V TV ++ R RS + D PP T VQ
Sbjct: 2991 YVCRAAGGPGPEQE-ASFTV----TVPPSEGSSYRLRSPVISID-PPSST-------VQQ 3037
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
C + G+ P + W +E+ N + + I T + G Y
Sbjct: 3038 GQDASFKCLIHDGAAPISLEWKTRNQEL----EDNVHISPNGSIITIVGTRPSNHGTYRC 3093
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N G L V V PE P++ + G + + V P
Sbjct: 3094 VASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVW-VKVGKAVTLECVSAGEPRSSAR 3147
Query: 3301 WYRDGVRLRPSRRAIMTLD-RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
W R + P++ T D L +++ DAG Y C A N +G A +VEVI
Sbjct: 3148 WTR--ISSTPAKLEQRTYGLMDSHTVLQISSAKPSDAGTYVCLAQNALGTAQK--QVEVI 3203
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P P V ++E + EA G T + C G P ++W
Sbjct: 3204 VDTGAMAPGAPQV-------QAEEAEL-----TVEA--GHTATLRCSATGSPARTIHW 3247
Score = 50.0 bits (114), Expect = 1e-04
Identities = 73/359 (20%), Positives = 128/359 (35%), Gaps = 45/359 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L CS S T+ W + L + L ++ +L TL + DS +
Sbjct: 3224 TVEAGHTATLRCSATGSPARTIHWSK----LRSPLPWQHRLEGD--TLIIPRVAQQDSGQ 3277
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C + G + L V A+ +P + +T L +C G P
Sbjct: 3278 YICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL-------QCLAHGTPPL 3330
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W + +P GR A L + PEDSG Y C+ N V + + +
Sbjct: 3331 TFQWSRVGSSLP--GRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3383
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
G + + A T + + + G ++ A G T++
Sbjct: 3384 VQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG-ASVEFHCAVPSDRG---------TQL 3433
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +EG + + V+ G+ L + ++ ++ G Y C+A G +A + +
Sbjct: 3434 RWFKEGGQLPPGHS-----VQDGV--LRIQNLDQSCQGTYICQAHGPWGKAQASAQLVI- 3485
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPG--EPCVVDGG 2960
P+V++ + VG + G+PKP+ ++ G P +V G
Sbjct: 3486 -----QALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG 3539
Score = 48.0 bits (109), Expect = 6e-04
Identities = 75/360 (20%), Positives = 127/360 (35%), Gaps = 35/360 (9%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SS++ V G P + I P ++ G+T +L C V G+ V W K G G
Sbjct: 2817 SSAVHVPAPGGAPP-IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRG-------GN 2868
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ ++ L + ++ D G YSC+ T G + T +VT +
Sbjct: 2869 LPARHQVHGPLLRLNQVSPADSGEYSCQVT---GSSGTLEASVLVT--------IEPSSP 2917
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
G P + + V + L C V G +V+WYK G + R++
Sbjct: 2918 GPIPAPGLAQPIY-IEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL---PARHQT 2973
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSG---AVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
Q ++P D G Y A G S + +G +
Sbjct: 2974 HGSQLRLHHVSPA---DSGEYVCRAAGGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDP 3030
Query: 3275 PLYKLHEGDELRISAVV-EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
P + +G + ++ + + + W L + + + +G I + +
Sbjct: 3031 PSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VHISPNGSI-ITIVGTRP 3085
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
+ G Y C ASN G A + + V G S PV + + E + +PRSS
Sbjct: 3086 SNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSS 3145
Score = 44.4 bits (100), Expect = 0.007
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
Query: 3065 GETANLTCSVKGKPVPGVV-WMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G+T TC G P P ++ W N + + R+T G L I+D+ D+G Y+
Sbjct: 421 GQTVTFTCVAIGVPAPFLINWRLNWGHIPSQP-RVTVTSEGGRGTLIIRDVKESDQGAYT 479
Query: 3124 CEATNTHG 3131
CEA N G
Sbjct: 480 CEAMNARG 487
Score = 41.9 bits (94), Expect = 0.039
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 18/170 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ V+ C+V S + W++ G +L + DG++ ++ L+ S Y C
Sbjct: 3416 GASVEFHCAVPSDRGTQLRWFKEG----GQLPPGHSVQDGVLRIQNLDQ--SCQGTYICQ 3469
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
G SA L + +A P R+ T + + + EC G P P++TW
Sbjct: 3470 AHGPWGKAQASAQLVI----QALPSVLINIRTSVQTV-VVGHAVEFECLALGDPKPQVTW 3524
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K + G Q+ GV R+A + D+G Y C A N+ T Q
Sbjct: 3525 SKVGGHL-RPGIVQS----GGVVRIA--HVELADAGQYRCTATNAAGTTQ 3567
Score = 41.5 bits (93), Expect = 0.052
Identities = 45/185 (24%), Positives = 67/185 (36%), Gaps = 18/185 (9%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L CQV G P W ++ V + ++Q + H + P+ D GVY T RN
Sbjct: 1698 LRCQVSGRGPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPS---DAGVYICTCRNLH 1754
Query: 3247 GAVSCHCGLVV----DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+ + L+V K I V + + P D I P+ + W
Sbjct: 1755 RSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP-----GADVTFICTAKSKSPAYTLVW- 1808
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
RL + +D +G L + V DAG Y CT SN + + V +
Sbjct: 1809 ---TRLHNGKLPTRAMDFNG--ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASG 1863
Query: 3363 QTSEP 3367
S P
Sbjct: 1864 TLSAP 1868
Score = 39.9 bits (89), Expect = 0.16
Identities = 53/234 (22%), Positives = 78/234 (33%), Gaps = 40/234 (17%)
Query: 3031 WGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
WG++ ++ + L ++I ++ G C G P P V W K G
Sbjct: 3474 WGKAQASAQLVIQALPS---VLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH 3530
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
+ Q G + I + + D G+Y C ATN G ++ L V
Sbjct: 3531 LRPGI----VQSGGV---VRIAHVELADAGQYRCTATNAAGTTQSHVLLLV--------- 3574
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
PQ +M ++ RV A C G P P +SW K +
Sbjct: 3575 --------------QALPQISMP-QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPP 3619
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
D R + L + D G Y TA N G V L V + + Y
Sbjct: 3620 DSRLEN------NMLMLPSVQPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPY 3667
Score = 35.1 bits (77), Expect = 4.5
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 3/74 (4%)
Query: 2823 QVARGGTIGLQVEIRGCPTR--VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
Q +RG T+ G P + W + R V E G TL + DV E++
Sbjct: 417 QASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPR-VTVTSEGGRGTLIIRDVKESDQ 475
Query: 2881 GLYTCRAWSAHGNV 2894
G YTC A +A G V
Sbjct: 476 GAYTCEAMNARGMV 489
Score = 34.7 bits (76), Expect = 5.9
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 10/105 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
GS C P ++W + LD L +L + ++ L + P D+ Y CT
Sbjct: 3591 GSAAVFPCIASGYPTPDISWSK----LDGSLPPDSRLENNMLMLPSVQ--PQDAGTYVCT 3644
Query: 2668 VENENGAISTSANL----KVYPSFEASPIPPTFTRSIRDTFHLAE 2708
N G + A+L +V P F +P +I+D + E
Sbjct: 3645 ATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFE 3689
>X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein.
Length = 1123
Score = 82.2 bits (194), Expect = 3e-14
Identities = 45/115 (39%), Positives = 61/115 (53%), Gaps = 5/115 (4%)
Query: 2667 TVENENGAISTSANL---KVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
T+ E+ I+ + VY F+ S P FT+ + +T+ +A L C +RG P P
Sbjct: 1000 TMTKESAVIARDGKIYKNPVYEDFDFSEAP-MFTQPLVNTYAIAGYNATLNCSVRGNPKP 1058
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
KITW K+ I D RY+ F GVC L I P+P D GTY CKA N + T +I
Sbjct: 1059 KITWMKNKVAIVDDPRYRMF-SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1112
Score = 60.5 bits (140), Expect = 1e-07
Identities = 33/90 (36%), Positives = 44/90 (48%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L + A Y L C V G+P PK++W K+ +V D R + ++ TLEI
Sbjct: 1029 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1088
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ DGG Y A N+ G V C L V
Sbjct: 1089 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 58.0 bits (134), Expect = 6e-07
Identities = 28/90 (31%), Positives = 43/90 (47%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F+ L + A+ G L CSV + P +TW +N V + + +YR G+ TLE+
Sbjct: 1029 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1088
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
P D Y C N+ G + L+V
Sbjct: 1089 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 56.0 bits (129), Expect = 2e-06
Identities = 60/211 (28%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 2951 PGEPCVVDGGNNW---VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE-LGITPLN 3006
PG P +V + W V+L W A + Y ++ + W +
Sbjct: 914 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQK---ADKKSMEWFTVIEHYHRT 970
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGE-SSQTSSSIGVGLAG--------------DRPE 3051
S L G EY+FRV N G E ++ T S + G + P
Sbjct: 971 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1030
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLT 3110
F L I AG A L CSV+G P P + WMKN V++ RM S N C L
Sbjct: 1031 FTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NQGVCTLE 1087
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
I+ + D G Y C+A N G +L V
Sbjct: 1088 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 54.0 bits (124), Expect = 9e-06
Identities = 98/405 (24%), Positives = 163/405 (40%), Gaps = 62/405 (15%)
Query: 2574 SEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPT--VTWYRN 2630
++ R ++ + + R + F+ L V+ G RV+ V+ +DP V WY+N
Sbjct: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRF---VVELADPKLEVKWYKN 288
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
G + KY + L + N +D +EY T +E S L F
Sbjct: 289 GQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK----CSTEL-----FVRE 339
Query: 2691 PIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC 2750
P P T+ + DT + LEC + + + WFK+ ++I + + +G
Sbjct: 340 P-PIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
Query: 2751 R-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L I+ T D+ AE SV T TG +S K + + L+
Sbjct: 398 HILIIEGATKADA------AEYSVMT---------TGGQSSA--------KLSVDLKPLK 434
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEI-RGCPTRVEWLREGRSVTEVYRNARVFVEQGLY 2868
P LTD V G I L+ EI P + W + G V E R +V + ++
Sbjct: 435 ILTP-----LTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDR-LKVVHKGRIH 486
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD--LDGKPAVIVGRPEKDILIS 2926
L +++ + G Y A A+ NV + A + V+ P LDG A + + +
Sbjct: 487 KLVIANALTEDEGDYVF-APDAY-NVTLPAKVHVIDPPKIILDGLDA------DNTVTVI 538
Query: 2927 VGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
G + + GEP PKA+ R G+ +++G + ++P S
Sbjct: 539 AGNKLRLEIPISGEPPPKAMWSR--GDKAIMEGSGRIRTESYPDS 581
Score = 51.6 bits (118), Expect = 5e-05
Identities = 47/175 (26%), Positives = 73/175 (41%), Gaps = 9/175 (5%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV 2657
T LTD+T G + L C IS + P W +NG+ + + + + L + NA+
Sbjct: 437 TPLTDQTVNLGKEICLKCE-ISENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D +Y + N + ++ P + T ++ +A N+L LE I
Sbjct: 495 TEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTV-----IAGNKLRLEIPI 549
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
G+P PK W + DK I GR + D L ID +DSG Y +N
Sbjct: 550 SGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERDDSGVYHINLKN 603
Score = 42.3 bits (95), Expect = 0.030
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 21/223 (9%)
Query: 3157 ERSAEVEGDYPP-QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN 3215
+ SA++ D P + L D+ V + L C++ + P K W K+G V R
Sbjct: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLK 478
Query: 3216 KYQDEQFHTLEIAPTNLDDGG--VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC-G 3272
+ H L IA +D G V+ A N + H V+D P+ G
Sbjct: 479 VVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDP-------PKIILDG 528
Query: 3273 LEP--LYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
L+ + G++LR+ + P W R + I T L +
Sbjct: 529 LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 588
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVV 3373
D+GVY NE G A S KV+V+ +P + P V
Sbjct: 589 AERDDSGVYHINLKNEAGEAHASIKVKVV---DFPDPPVAPTV 628
Score = 40.3 bits (90), Expect = 0.12
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++AG L + G+P P +W + + E +GR+ ++ L I DD G
Sbjct: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y N G+A ++ VV
Sbjct: 597 YHINLKNEAGEAHASIKVKVV 617
Score = 39.1 bits (87), Expect = 0.28
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + G L +RG P ++ W++ ++ + R R+F QG+
Sbjct: 1026 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY-RMFSNQGVC 1084
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
TL + + + G Y C+A + G V++ + V
Sbjct: 1085 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 35.5 bits (78), Expect = 3.4
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 3273 LEPLYKLHEGDELRISAVVE-AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P Y++ +G +R VVE A P + V WY++G +RPS + I + Q L +
Sbjct: 258 LDPAYQVDKGGRVRF--VVELADPKLEVKWYKNGQEIRPSTKYIFE-HKGCQRILFINNC 314
Query: 3332 TTRDAGVYTCTASNE 3346
D Y TA +E
Sbjct: 315 QMTDDSEYYVTAGDE 329
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 3377 DVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
D +S+ PMF + ++ A G + C V G+PKP + W+++
Sbjct: 1022 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1065
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP F L Y + G ++ V P +TW ++ V + R M G
Sbjct: 1028 APMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCT 1085
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L + + D G Y C A N++G K+EV
Sbjct: 1086 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
>BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein.
Length = 1120
Score = 82.2 bits (194), Expect = 3e-14
Identities = 45/115 (39%), Positives = 61/115 (53%), Gaps = 5/115 (4%)
Query: 2667 TVENENGAISTSANL---KVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
T+ E+ I+ + VY F+ S P FT+ + +T+ +A L C +RG P P
Sbjct: 974 TMTKESAVIARDGKIYKNPVYEDFDFSEAP-MFTQPLVNTYAIAGYNATLNCSVRGNPKP 1032
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
KITW K+ I D RY+ F GVC L I P+P D GTY CKA N + T +I
Sbjct: 1033 KITWMKNKVAIVDDPRYRMF-SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1086
Score = 62.1 bits (144), Expect = 3e-08
Identities = 40/119 (33%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L + A Y L C V G+P PK++W K+ +V D R + ++ TLEI
Sbjct: 1003 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1062
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGL---VVDKGIRAYVAPEFCCGLEPLYKLHEGD 3283
+ DGG Y A N+ G V C L V+ +G+ P F G + LH D
Sbjct: 1063 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQ--QSLHNKD 1119
Score = 61.3 bits (142), Expect = 6e-08
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 2/114 (1%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F+ L + A+ G L CSV + P +TW +N V + + +YR G+ TLE+
Sbjct: 1003 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1062
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEA--SPIPPTFTRSIRDTFH 2705
P D Y C N+ G + L+V ++ +P P F + + H
Sbjct: 1063 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSLH 1116
Score = 56.0 bits (129), Expect = 2e-06
Identities = 60/211 (28%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 2951 PGEPCVVDGGNNW---VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE-LGITPLN 3006
PG P +V + W V+L W A + Y ++ + W +
Sbjct: 888 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQK---ADKKSMEWFTVIEHYHRT 944
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGE-SSQTSSSIGVGLAG--------------DRPE 3051
S L G EY+FRV N G E ++ T S + G + P
Sbjct: 945 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1004
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLT 3110
F L I AG A L CSV+G P P + WMKN V++ RM S N C L
Sbjct: 1005 FTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NQGVCTLE 1061
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
I+ + D G Y C+A N G +L V
Sbjct: 1062 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1092
Score = 54.0 bits (124), Expect = 9e-06
Identities = 98/405 (24%), Positives = 163/405 (40%), Gaps = 62/405 (15%)
Query: 2574 SEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPT--VTWYRN 2630
++ R ++ + + R + F+ L V+ G RV+ V+ +DP V WY+N
Sbjct: 206 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRF---VVELADPKLEVKWYKN 262
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
G + KY + L + N +D +EY T +E S L F
Sbjct: 263 GQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK----CSTEL-----FVRE 313
Query: 2691 PIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC 2750
P P T+ + DT + LEC + + + WFK+ ++I + + +G
Sbjct: 314 P-PIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 371
Query: 2751 R-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L I+ T D+ AE SV T TG +S K + + L+
Sbjct: 372 HILIIEGATKADA------AEYSVMT---------TGGQSSA--------KLSVDLKPLK 408
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEI-RGCPTRVEWLREGRSVTEVYRNARVFVEQGLY 2868
P LTD V G I L+ EI P + W + G V E R +V + ++
Sbjct: 409 ILTP-----LTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDR-LKVVHKGRIH 460
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD--LDGKPAVIVGRPEKDILIS 2926
L +++ + G Y A A+ NV + A + V+ P LDG A + + +
Sbjct: 461 KLVIANALTEDEGDYVF-APDAY-NVTLPAKVHVIDPPKIILDGLDA------DNTVTVI 512
Query: 2927 VGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
G + + GEP PKA+ R G+ +++G + ++P S
Sbjct: 513 AGNKLRLEIPISGEPPPKAMWSR--GDKAIMEGSGRIRTESYPDS 555
Score = 51.6 bits (118), Expect = 5e-05
Identities = 47/175 (26%), Positives = 73/175 (41%), Gaps = 9/175 (5%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV 2657
T LTD+T G + L C IS + P W +NG+ + + + + L + NA+
Sbjct: 411 TPLTDQTVNLGKEICLKCE-ISENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 468
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D +Y + N + ++ P + T ++ +A N+L LE I
Sbjct: 469 TEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTV-----IAGNKLRLEIPI 523
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
G+P PK W + DK I GR + D L ID +DSG Y +N
Sbjct: 524 SGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERDDSGVYHINLKN 577
Score = 42.3 bits (95), Expect = 0.030
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 21/223 (9%)
Query: 3157 ERSAEVEGDYPP-QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN 3215
+ SA++ D P + L D+ V + L C++ + P K W K+G V R
Sbjct: 395 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLK 452
Query: 3216 KYQDEQFHTLEIAPTNLDDGG--VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC-G 3272
+ H L IA +D G V+ A N + H V+D P+ G
Sbjct: 453 VVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDP-------PKIILDG 502
Query: 3273 LEP--LYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
L+ + G++LR+ + P W R + I T L +
Sbjct: 503 LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 562
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVV 3373
D+GVY NE G A S KV+V+ +P + P V
Sbjct: 563 AERDDSGVYHINLKNEAGEAHASIKVKVV---DFPDPPVAPTV 602
Score = 41.1 bits (92), Expect = 0.068
Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + G L +RG P ++ W++ ++ + R R+F QG+
Sbjct: 1000 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY-RMFSNQGVC 1058
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAI---TVVQPSDLDGKPAVIVGRPE 2920
TL + + + G Y C+A + G V++ + + Q + G+P + G+ +
Sbjct: 1059 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQ 1113
Score = 40.3 bits (90), Expect = 0.12
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++AG L + G+P P +W + + E +GR+ ++ L I DD G
Sbjct: 511 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 570
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y N G+A ++ VV
Sbjct: 571 YHINLKNEAGEAHASIKVKVV 591
Score = 35.5 bits (78), Expect = 3.4
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 3273 LEPLYKLHEGDELRISAVVE-AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P Y++ +G +R VVE A P + V WY++G +RPS + I + Q L +
Sbjct: 232 LDPAYQVDKGGRVRF--VVELADPKLEVKWYKNGQEIRPSTKYIFE-HKGCQRILFINNC 288
Query: 3332 TTRDAGVYTCTASNE 3346
D Y TA +E
Sbjct: 289 QMTDDSEYYVTAGDE 303
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 3377 DVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
D +S+ PMF + ++ A G + C V G+PKP + W+++
Sbjct: 996 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1039
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP F L Y + G ++ V P +TW ++ V + R M G
Sbjct: 1002 APMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCT 1059
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L + + D G Y C A N++G K+EV
Sbjct: 1060 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1092
>BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein C,
slow type protein.
Length = 1123
Score = 82.2 bits (194), Expect = 3e-14
Identities = 45/115 (39%), Positives = 61/115 (53%), Gaps = 5/115 (4%)
Query: 2667 TVENENGAISTSANL---KVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
T+ E+ I+ + VY F+ S P FT+ + +T+ +A L C +RG P P
Sbjct: 1000 TMTKESAVIARDGKIYKNPVYEDFDFSEAP-MFTQPLVNTYAIAGYNATLNCSVRGNPKP 1058
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
KITW K+ I D RY+ F GVC L I P+P D GTY CKA N + T +I
Sbjct: 1059 KITWMKNKVAIVDDPRYRMF-SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1112
Score = 60.5 bits (140), Expect = 1e-07
Identities = 33/90 (36%), Positives = 44/90 (48%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L + A Y L C V G+P PK++W K+ +V D R + ++ TLEI
Sbjct: 1029 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1088
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ DGG Y A N+ G V C L V
Sbjct: 1089 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 58.0 bits (134), Expect = 6e-07
Identities = 28/90 (31%), Positives = 43/90 (47%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F+ L + A+ G L CSV + P +TW +N V + + +YR G+ TLE+
Sbjct: 1029 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1088
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
P D Y C N+ G + L+V
Sbjct: 1089 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 56.0 bits (129), Expect = 2e-06
Identities = 60/211 (28%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 2951 PGEPCVVDGGNNW---VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVE-LGITPLN 3006
PG P +V + W V+L W A + Y ++ + W +
Sbjct: 914 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQK---ADKKSMEWFTVIEHYHRT 970
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGE-SSQTSSSIGVGLAG--------------DRPE 3051
S L G EY+FRV N G E ++ T S + G + P
Sbjct: 971 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1030
Query: 3052 FVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLT 3110
F L I AG A L CSV+G P P + WMKN V++ RM S N C L
Sbjct: 1031 FTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NQGVCTLE 1087
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
I+ + D G Y C+A N G +L V
Sbjct: 1088 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 54.0 bits (124), Expect = 9e-06
Identities = 98/405 (24%), Positives = 163/405 (40%), Gaps = 62/405 (15%)
Query: 2574 SEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPT--VTWYRN 2630
++ R ++ + + R + F+ L V+ G RV+ V+ +DP V WY+N
Sbjct: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRF---VVELADPKLEVKWYKN 288
Query: 2631 GVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEAS 2690
G + KY + L + N +D +EY T +E S L F
Sbjct: 289 GQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK----CSTEL-----FVRE 339
Query: 2691 PIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC 2750
P P T+ + DT + LEC + + + WFK+ ++I + + +G
Sbjct: 340 P-PIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
Query: 2751 R-LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLE 2809
L I+ T D+ AE SV T TG +S K + + L+
Sbjct: 398 HILIIEGATKADA------AEYSVMT---------TGGQSSA--------KLSVDLKPLK 434
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEI-RGCPTRVEWLREGRSVTEVYRNARVFVEQGLY 2868
P LTD V G I L+ EI P + W + G V E R +V + ++
Sbjct: 435 ILTP-----LTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDR-LKVVHKGRIH 486
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD--LDGKPAVIVGRPEKDILIS 2926
L +++ + G Y A A+ NV + A + V+ P LDG A + + +
Sbjct: 487 KLVIANALTEDEGDYVF-APDAY-NVTLPAKVHVIDPPKIILDGLDA------DNTVTVI 538
Query: 2927 VGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
G + + GEP PKA+ R G+ +++G + ++P S
Sbjct: 539 AGNKLRLEIPISGEPPPKAMWSR--GDKAIMEGSGRIRTESYPDS 581
Score = 51.6 bits (118), Expect = 5e-05
Identities = 47/175 (26%), Positives = 73/175 (41%), Gaps = 9/175 (5%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV 2657
T LTD+T G + L C IS + P W +NG+ + + + + L + NA+
Sbjct: 437 TPLTDQTVNLGKEICLKCE-ISENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D +Y + N + ++ P + T ++ +A N+L LE I
Sbjct: 495 TEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTV-----IAGNKLRLEIPI 549
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
G+P PK W + DK I GR + D L ID +DSG Y +N
Sbjct: 550 SGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERDDSGVYHINLKN 603
Score = 42.3 bits (95), Expect = 0.030
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 21/223 (9%)
Query: 3157 ERSAEVEGDYPP-QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN 3215
+ SA++ D P + L D+ V + L C++ + P K W K+G V R
Sbjct: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLK 478
Query: 3216 KYQDEQFHTLEIAPTNLDDGG--VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC-G 3272
+ H L IA +D G V+ A N + H V+D P+ G
Sbjct: 479 VVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDP-------PKIILDG 528
Query: 3273 LEP--LYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
L+ + G++LR+ + P W R + I T L +
Sbjct: 529 LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 588
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVV 3373
D+GVY NE G A S KV+V+ +P + P V
Sbjct: 589 AERDDSGVYHINLKNEAGEAHASIKVKVV---DFPDPPVAPTV 628
Score = 40.3 bits (90), Expect = 0.12
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++AG L + G+P P +W + + E +GR+ ++ L I DD G
Sbjct: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y N G+A ++ VV
Sbjct: 597 YHINLKNEAGEAHASIKVKVV 617
Score = 39.1 bits (87), Expect = 0.28
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + G L +RG P ++ W++ ++ + R R+F QG+
Sbjct: 1026 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY-RMFSNQGVC 1084
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
TL + + + G Y C+A + G V++ + V
Sbjct: 1085 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 35.5 bits (78), Expect = 3.4
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 3273 LEPLYKLHEGDELRISAVVE-AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P Y++ +G +R VVE A P + V WY++G +RPS + I + Q L +
Sbjct: 258 LDPAYQVDKGGRVRF--VVELADPKLEVKWYKNGQEIRPSTKYIFE-HKGCQRILFINNC 314
Query: 3332 TTRDAGVYTCTASNE 3346
D Y TA +E
Sbjct: 315 QMTDDSEYYVTAGDE 329
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 3377 DVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
D +S+ PMF + ++ A G + C V G+PKP + W+++
Sbjct: 1022 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1065
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP F L Y + G ++ V P +TW ++ V + R M G
Sbjct: 1028 APMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCT 1085
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L + + D G Y C A N++G K+EV
Sbjct: 1086 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 82.2 bits (194), Expect = 3e-14
Identities = 89/353 (25%), Positives = 139/353 (39%), Gaps = 49/353 (13%)
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAG 3065
+S++ + EE + T +R G G + + + P+ V + + G
Sbjct: 442 SSWEILRASKAEEGTYECTAVSRAGTGRAKAQ-----IVVTDPPPQLVPA--PNVTVSPG 494
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
ETA L+C V G+ + W+++ + GR+ D L I I D GRY C
Sbjct: 495 ETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLA---DLSLEISGIIPTDGGRYQCV 551
Query: 3126 ATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPV 3185
A+N +G VT +VW L RE PQ ++ + V
Sbjct: 552 ASNANG----------VTRASVW----LLVREA---------PQVSIHTSSQHFSQGVEV 588
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
+++C G P P +SW ++ + + D R + D Q TL I +D G Y A N
Sbjct: 589 KVSCSASGYPTPHISWSRESQALQEDSRI--HVDAQ-GTLIIQGVAPEDAGNYSCQATNE 645
Query: 3246 SGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G L Y P + + + G+E + P V WYR G
Sbjct: 646 VGTDQETVTLY-------YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG 698
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+ + I+ + +L + A RDAG YTC A NE+G AS ++ V
Sbjct: 699 LEM------ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745
Score = 80.2 bits (189), Expect = 1e-13
Identities = 56/194 (28%), Positives = 84/194 (43%), Gaps = 15/194 (7%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L+C V+ + +TW R+ +L +L D ++LE+ +P+D
Sbjct: 490 TVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLAD--LSLEISGIIPTDGGR 547
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN-ELVLECRIRGQPL 2722
Y C N NG S L V +P T S H ++ E+ + C G P
Sbjct: 548 YQCVASNANGVTRASVWLLV----REAPQVSIHTSSQ----HFSQGVEVKVSCSASGYPT 599
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
P I+W ++ + + D R D L I PED+G Y+C+A N V TDQ T +
Sbjct: 600 PHISWSRESQALQEDSRIHV----DAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 655
Query: 2783 NFTGRESQVSPNVV 2796
+T S + N V
Sbjct: 656 YYTDPPSVSAVNAV 669
Score = 66.1 bits (154), Expect = 2e-09
Identities = 68/269 (25%), Positives = 109/269 (40%), Gaps = 36/269 (13%)
Query: 3156 RERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN 3215
R ++ V D PPQ + + V L+C+V+G P ++W +D V
Sbjct: 469 RAKAQIVVTDPPPQL-VPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWR--VLPASTG 525
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEP 3275
+ +LEI+ DGG Y+ A N +G L+V + AP+
Sbjct: 526 RVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVRE------APQVSIHTSS 579
Query: 3276 LYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRD 3335
+ +G E+++S YP+ ++W R+ L+ R + D Q L + V D
Sbjct: 580 QH-FSQGVEVKVSCSASGYPTPHISWSRESQALQEDSR----IHVDAQGTLIIQGVAPED 634
Query: 3336 AGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEA 3395
AG Y+C A+NEVG + V + TD S + VV+
Sbjct: 635 AGNYSCQATNEVG--TDQETVTLYYTDPPSVSAVNAVVL--------------------V 672
Query: 3396 REGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
G+ ++ CE G P P V W R L++
Sbjct: 673 AVGEEAVLVCEASGVPPPRVIWYRGGLEM 701
Score = 59.3 bits (137), Expect = 2e-07
Identities = 81/337 (24%), Positives = 139/337 (41%), Gaps = 55/337 (16%)
Query: 2613 LTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENEN 2672
++CSV S+ + R L + +++ G + E+L A ++ Y CT +
Sbjct: 409 VSCSVHSALPFRLQLRRGEARLGEERHFQES---GNSSWEILRASKAEEGTYECTAVSRA 465
Query: 2673 GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDK 2732
G A + V P PP + T E VL CR+ G+ +TW +D +
Sbjct: 466 GTGRAKAQIVV-----TDP-PPQLVPAPNVTVSPGET-AVLSCRVLGEAPYNLTWVRDWR 518
Query: 2733 QIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQV 2791
+P S GR LAD L I P D G Y C A N+ + +T +
Sbjct: 519 VLPASTGR--VAQLAD--LSLEISGIIPTDGGRYQCVASNA---NGVT----------RA 561
Query: 2792 SPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGR 2850
S ++ E ++ S+ + HF ++G + + G PT + W RE +
Sbjct: 562 SVWLLVREAPQV---SIHTSSQHF---------SQGVEVKVSCSASGYPTPHISWSRESQ 609
Query: 2851 SVTEVYRNARVFVE-QGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLD 2909
++ E ++R+ V+ QG TL + V ++G Y+C+A + G + P +
Sbjct: 610 ALQE---DSRIHVDAQG--TLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVS 664
Query: 2910 GKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
AV +L++VGE+ + G P P+ +
Sbjct: 665 AVNAV--------VLVAVGEEAVLVCEASGVPPPRVI 693
Score = 58.4 bits (135), Expect = 4e-07
Identities = 47/182 (25%), Positives = 70/182 (38%), Gaps = 20/182 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P S + + +G VK++CS P ++W R L + VD TL +
Sbjct: 571 PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIH---VDAQGTLII 627
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
P D+ YSC NE G + L Y PP+ + E VL
Sbjct: 628 QGVAPEDAGNYSCQATNEVGTDQETVTL-YYTD------PPSVSAVNAVVLVAVGEEAVL 680
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC--RLAIDNPTPEDSGTYTCKAEN 2771
C G P P++ W++ G + +G +L I D+GTYTC+A N
Sbjct: 681 VCEASGVPPPRVIWYR--------GGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVN 732
Query: 2772 SV 2773
+
Sbjct: 733 EL 734
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 81.4 bits (192), Expect = 5e-14
Identities = 91/357 (25%), Positives = 151/357 (42%), Gaps = 44/357 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R ++ L+ L ++ P+DS EYSC
Sbjct: 2840 EGQTLDLKCVVPGQAHAQVTWHKRG----GNLPARHQVHGPLLRLNQVS--PADSGEYSC 2893
Query: 2667 TVENENGAISTSANLKVYPSFEASPIP-PTFTRSI---RDTFHLAENE-LVLECRIRGQP 2721
V +G + S + + PS PIP P + I + H+ E + L L C + GQ
Sbjct: 2894 QVTGSSGTLEASVLVTIEPS-SPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQA 2952
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
++TW+K +P+ R+Q +L + +P DSG Y C+A + +Q F
Sbjct: 2953 HAQVTWYKRGGSLPA--RHQTH-----GSQLRLHLVSPADSGEYVCRAASGPGPEQEASF 3005
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V P+ ++ + R S++ P V Q + + + P
Sbjct: 3006 T------VTVPPSEGSSYRLRSPVISID---PPSSTV----QQGQDASFKCLIHDGAAPI 3052
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+EW + E+ N + + T+ + G Y C A +A+G A +
Sbjct: 3053 SLEWKTRNQ---ELEDNVHISPNGSIITIV--GTRPSNHGTYRCVASNAYG-----VAQS 3102
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
VV S + G P V V PE + + VG+ + + + GEP+ A RI P ++
Sbjct: 3103 VVNLS-VHGPPTVSV-LPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLE 3157
Score = 80.6 bits (190), Expect = 9e-14
Identities = 97/366 (26%), Positives = 132/366 (36%), Gaps = 49/366 (13%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V I P QL + G+ A CS G P P + W G++ ++ L +
Sbjct: 1868 VSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGG------PGGQLPAKAQIHGGILRLP 1921
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D+ +Y C A H A AV+ V G P+ +
Sbjct: 1922 AVEPTDQAQYLCRA---HSSAGQQVARAVL------------------HVHGGGGPRVQV 1960
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+V A VRL C+ G P ++W K+G + R + TL I
Sbjct: 1961 SPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSER---TDIATLLIPAITT 2017
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE 3292
D G Y A + +G +VV A P + EG L ++ VV
Sbjct: 2018 ADAGFYLCVATSPAGTAQARMQVVVLSASDASPPGVKIESSSP--SVTEGQTLDLNCVVA 2075
Query: 3293 AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
VTWYR G L P + G L L V+ D+G Y C N G
Sbjct: 2076 GSAHAQVTWYRRGGSLPPHTQV------HGS-RLRLPQVSPADSGEYVCRVENGSGPKEA 2128
Query: 3353 SGKVEVI-GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S V V+ GT S P P VP S P+ I +P SS EG T+ + C V G
Sbjct: 2129 SITVSVLHGTH--SGPSYTP------VPGSTRPIRI-EPSSSHVAEGQTLDLNCVVPGQA 2179
Query: 3412 KPDVYW 3417
V W
Sbjct: 2180 HAQVTW 2185
Score = 80.2 bits (189), Expect = 1e-13
Identities = 85/321 (26%), Positives = 132/321 (41%), Gaps = 39/321 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T VEG + L C V +TWY+ G L R + + L ++ +DS E
Sbjct: 2640 TVVEGQTLDLNCVVARQPQAIITWYKRG----GSLPSRHQTHGSHLRLHQMSV--ADSGE 2693
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---DTFHLAENE-LVLECRIRG 2719
Y C N A+ S + V PS SP P + IR + H+AE E L L C + G
Sbjct: 2694 YVCRANNNIDALEASIVISVSPS-AGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2752
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
Q ++TW K +PS + + RL + + +P DSG Y C+ S + +
Sbjct: 2753 QAHAQVTWHKRGGSLPSHHQTRG-------SRLRLHHVSPADSGEYVCRVMGSSGPLEAS 2805
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V S I + SR VA G T+ L+ + G
Sbjct: 2806 VLVTIEASGSSAVHVPAPGGAPPIRIEPSSSR------------VAEGQTLDLKCVVPGQ 2853
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G ++ AR V L L L+ V+ +SG Y+C+ + G ++ +
Sbjct: 2854 AHAQVTWHKRGGNLP-----ARHQVHGPL--LRLNQVSPADSGEYSCQVTGSSGTLEASV 2906
Query: 2899 AITVVQPSDLDGKPAVIVGRP 2919
+T ++PS PA + +P
Sbjct: 2907 LVT-IEPSSPGPIPAPGLAQP 2926
Score = 78.2 bits (184), Expect = 5e-13
Identities = 91/356 (25%), Positives = 147/356 (41%), Gaps = 46/356 (12%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTA--VEGSRVKLTCSVISSSDPTVTW 2627
S EA +++ ++ LS + ++ + + +A G + L C V S + T+TW
Sbjct: 2508 SSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITW 2567
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
Y+ G L R ++V L + P+DS EY C V N G+ TS + + S
Sbjct: 2568 YKRG----GSLPSRHQIVGS--RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG 2621
Query: 2688 EA---SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+ S PP S T + L L C + QP ITW+K +PS R+Q
Sbjct: 2622 SSHVPSVSPPIRIESSSPTV-VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RHQTHG 2678
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
L + + DSG Y C+A N++ D + + + S SP+ +
Sbjct: 2679 -----SHLRLHQMSVADSGEYVCRANNNI--DALEASIVISVSPSAGSPSAPGSSMP--- 2728
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFV 2863
+ES H VA G T+ L + G +V W + G S+ ++
Sbjct: 2729 -IRIESSSSH---------VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQT----- 2773
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP 2919
+G L L V+ +SG Y CR + G ++ + +T+ + G AV V P
Sbjct: 2774 -RG-SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI----EASGSSAVHVPAP 2823
Score = 75.8 bits (178), Expect = 3e-12
Identities = 90/358 (25%), Positives = 132/358 (36%), Gaps = 60/358 (16%)
Query: 3065 GETANLTCSVKGK-PVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
G C+ K K P +VW + + G++ ++ F+ LTI+++ + D G Y
Sbjct: 1786 GADVTFICTAKSKSPAYTLVWTRLHN------GKLPTRAMDFNGILTIRNVQLSDAGTYV 1839
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C +N A L V T+ SA V +PPQ T VQ
Sbjct: 1840 CTGSNMFAMDQGTATLHVQASGTL-----------SAPVVSIHPPQLT-------VQPGQ 1881
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
C GSP P + W G + + + PT D Y A
Sbjct: 1882 LAEFRCSATGSPTPTLEW--TGGPGGQLPAKAQIHGGILRLPAVEPT---DQAQYLCRAH 1936
Query: 3244 NNSGAVSCHCGLVV--DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+++G L V G R V+PE ++H G +R+ PS +TW
Sbjct: 1937 SSAGQQVARAVLHVHGGGGPRVQVSPE-------RTQVHAGRTVRLYCRAAGVPSATITW 1989
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++G L P R+ +R L + A+TT DAG Y C A++ G A +V V+
Sbjct: 1990 RKEGGSLPPQARS----ERTDIATLLIPAITTADAGFYLCVATSPAGTAQARMQVVVLSA 2045
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
S P + SP V EG T+ + C V G V W R
Sbjct: 2046 SDASPPGVKIESSSPSV-----------------TEGQTLDLNCVVAGSAHAQVTWYR 2086
Score = 74.9 bits (176), Expect = 5e-12
Identities = 78/298 (26%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R + L+ L P+DS EY C
Sbjct: 2165 EGQTLDLNCVVPGQAHAQVTWHKRG----GSLPARHQTHGSLLRLH--QVTPADSGEYVC 2218
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKI 2725
V +G + S + + S PIPP S T +AE + L L C + GQ ++
Sbjct: 2219 HVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSST--VAEGQTLDLSCVVAGQAHAQV 2276
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
TW+K +P+ R+Q RL I +P D+G Y C+A N
Sbjct: 2277 TWYKRGGSLPA--RHQV-----RGSRLYIFQASPADAGQYVCRASN-------------- 2315
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVE 2844
G E+ ++ V + +A + S +P + QVA G T+ L + G +V
Sbjct: 2316 GMEASITVTVTGTQGANLAYPA-GSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT 2373
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
W + G S+ ++ G L L + +SG Y CR + ++ + +T+
Sbjct: 2374 WHKRGGSLPVRHQT------HG-SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2424
Score = 69.3 bits (162), Expect = 2e-10
Identities = 90/327 (27%), Positives = 135/327 (41%), Gaps = 56/327 (17%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
LS + P + + EG + L C V S+ VTWYR G L + V
Sbjct: 2043 LSASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQ-----V 2097
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASP--IP-PTFTRSIR- 2701
G L + P+DS EY C VEN +G S + V + P P P TR IR
Sbjct: 2098 HG-SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRI 2156
Query: 2702 --DTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPT 2758
+ H+AE + L L C + GQ ++TW K +P+ R+Q L + T
Sbjct: 2157 EPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RHQTH-----GSLLRLHQVT 2209
Query: 2759 PEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
P DSG Y C + + + V E+ V P + + +ES
Sbjct: 2210 PADSGEYVCHVVGTSGPLEASVLVTI---EASVIPGPIPPVR-------IES-------- 2251
Query: 2819 LTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVY--RNARVFVEQGLYTLALSDV 2875
+ VA G T+ L + G +V W + G S+ + R +R+++ Q
Sbjct: 2252 -SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ---------A 2301
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITV 2902
+ ++G Y CRA ++G M A+ITV
Sbjct: 2302 SPADAGQYVCRA--SNG---MEASITV 2323
Score = 68.9 bits (161), Expect = 3e-10
Identities = 82/312 (26%), Positives = 124/312 (39%), Gaps = 41/312 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V S VTW++ G L R + L+ L A P+DS EY C
Sbjct: 2354 EGQTLDLNCVVPGQSHAQVTWHKRG----GSLPVRHQTHGSLLRL--YQASPADSGEYVC 2407
Query: 2667 TVENENGAISTSANLKVYP--SFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP 2723
V + + S + + P S A + PT R + +AE + L L C + GQ
Sbjct: 2408 RVLGSSVPLEASVLVTIEPAGSVPALGVTPT-VRIESSSSQVAEGQTLDLNCLVAGQAHA 2466
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW K +P+ R+Q RL + TP DSG Y C+ S T + + V
Sbjct: 2467 QVTWHKRGGSLPA--RHQVH-----GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVT 2519
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTR 2842
R S S + A RI S +A G T+ L + P
Sbjct: 2520 IQQRLSG-SHSQGVAYPVRIESSSA--------------SLANGHTLDLNCLVASQAPHT 2564
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + G S+ ++ L + VT +SG Y C + G+ + + +T
Sbjct: 2565 ITWYKRGGSLPSRHQIVG-------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVT- 2616
Query: 2903 VQPSDLDGKPAV 2914
+Q S P+V
Sbjct: 2617 IQGSGSSHVPSV 2628
Score = 64.9 bits (151), Expect = 5e-09
Identities = 92/374 (24%), Positives = 137/374 (36%), Gaps = 58/374 (15%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V + P + ++ AG T L C G P + W K G + +A + L I
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDI----ATLLIP 2013
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
I D G Y C AT+ G A AR+ VV + +DA PP +
Sbjct: 2014 AITTADAGFYLCVATSPAGTAQ--ARMQVVV---LSASDAS-------------PPGVKI 2055
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L C V GS +V+WY+ G + + + +++P
Sbjct: 2056 ESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPHTQVHGSRLRLPQVSPA-- 2110
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG------LEPLYK-LHEGDEL 3285
D G Y N SG + V G + + G +EP + EG L
Sbjct: 2111 -DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTL 2169
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
++ VV VTW++ G L P+R G + L L VT D+G Y C
Sbjct: 2170 DLNCVVPGQAHAQVTWHKRGGSL-PARH-----QTHGSL-LRLHQVTPADSGEYVC---- 2218
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIEC 3405
V+GT E + + + +P P+ I + SS EG T+ + C
Sbjct: 2219 -----------HVVGTSGPLEASVLVTIEASVIPGPIPPVRI-ESSSSTVAEGQTLDLSC 2266
Query: 3406 EVVGDPKPDVYWLR 3419
V G V W +
Sbjct: 2267 VVAGQAHAQVTWYK 2280
Score = 62.1 bits (144), Expect = 3e-08
Identities = 83/342 (24%), Positives = 133/342 (38%), Gaps = 36/342 (10%)
Query: 2602 DRTAVEGSR-VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+RT V R V+L C T+TW + G L + R + D + TL + +D
Sbjct: 1963 ERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQA--RSERTD-IATLLIPAITTAD 2019
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
+ Y C + G + V + +ASP P S + + L L C + G
Sbjct: 2020 AGFYLCVATSPAGTAQARMQVVVLSASDASP-PGVKIESSSPSVTEGQT-LDLNCVVAGS 2077
Query: 2721 PLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
++TW++ +P + RL + +P DSG Y C+ EN + +
Sbjct: 2078 AHAQVTWYRRGGSLPPHTQVHG-------SRLRLPQVSPADSGEYVCRVENGSGPKEASI 2130
Query: 2781 FVN-FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V+ G S S V TR R +E H VA G T+ L + G
Sbjct: 2131 TVSVLHGTHSGPSYTPVPG-STRPIR--IEPSSSH---------VAEGQTLDLNCVVPGQ 2178
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G S+ AR L L L VT +SG Y C G ++ +
Sbjct: 2179 AHAQVTWHKRGGSLP-----ARHQTHGSL--LRLHQVTPADSGEYVCHVVGTSGPLEASV 2231
Query: 2899 AITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
+T ++ S + G P V ++ G+ +++S G+
Sbjct: 2232 LVT-IEASVIPG-PIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2271
Score = 62.1 bits (144), Expect = 3e-08
Identities = 87/356 (24%), Positives = 128/356 (35%), Gaps = 46/356 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G T +L C V + + W K G G + S+ L I + D G Y C
Sbjct: 2548 GHTLDLNCLVASQAPHTITWYKRG-------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+N G T +VT ++ S+ V PP + V
Sbjct: 2601 HVSNGAGSRETSL---IVT----------IQGSGSSHVPSVSPP-IRIESSSPTVVEGQT 2646
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ L C V P ++WYK G + +++Q H L + ++ D G Y A N
Sbjct: 2647 LDLNCVVARQPQAIITWYKRGGSLP-----SRHQTHGSH-LRLHQMSVADSGEYVCRANN 2700
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRISAVVEAYPSVGVTW 3301
N A+ + V + AP + + EG+ L ++ VV VTW
Sbjct: 2701 NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTW 2760
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++ G L PS G L L V+ D+G Y C G S V I
Sbjct: 2761 HKRGGSL-PSHHQTR-----GS-RLRLHHVSPADSGEYVCRVMGSSGPLEASVLV-TIEA 2812
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+S +P P P+ I +P SS EG T+ ++C V G V W
Sbjct: 2813 SGSSAVHVP-------APGGAPPIRI-EPSSSRVAEGQTLDLKCVVPGQAHAQVTW 2860
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/310 (27%), Positives = 121/310 (39%), Gaps = 51/310 (16%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG + L+C V + VTWY+ G L + + R L + A P+D+ +
Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGS------RLYIFQASPADAGQ 2308
Query: 2664 YSCTVENENGAIST-------SANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLEC 2715
Y C N A T ANL YP+ PI R + +AE + L L C
Sbjct: 2309 YVCRASNGMEASITVTVTGTQGANL-AYPAGSTQPI-----RIEPSSSQVAEGQTLDLNC 2362
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ GQ ++TW K +P R+Q + RL +P DSG Y C+ S +
Sbjct: 2363 VVPGQSHAQVTWHKRGGSLPV--RHQTH---GSLLRLY--QASPADSGEYVCRVLGS--S 2413
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ V T + P + RI S QVA G T+ L
Sbjct: 2414 VPLEASVLVTIEPAGSVPALGVTPTVRIESSS--------------SQVAEGQTLDLNCL 2459
Query: 2836 IRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
+ G +V W + G S+ AR V L L VT +SG Y CR + G
Sbjct: 2460 VAGQAHAQVTWHKRGGSLP-----ARHQVHGS--RLRLLQVTPADSGEYVCRVVGSSGTQ 2512
Query: 2895 DMNAAITVVQ 2904
+ + +T+ Q
Sbjct: 2513 EASVLVTIQQ 2522
Score = 60.9 bits (141), Expect = 8e-08
Identities = 80/364 (21%), Positives = 135/364 (37%), Gaps = 50/364 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ G+T +L C V +P + W K G G + S+ L + +++ D G
Sbjct: 2641 VVEGQTLDLNCVVARQPQAIITWYKRG-------GSLPSRHQTHGSHLRLHQMSVADSGE 2693
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A N ++V S G P + V
Sbjct: 2694 YVCRANNNIDALEASIVISVSPSAG------------SPSAPGSSMP-IRIESSSSHVAE 2740
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + ++ + + ++P D G Y
Sbjct: 2741 GETLDLNCVVPGQAHAQVTWHKRGGSL---PSHHQTRGSRLRLHHVSPA---DSGEYVCR 2794
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY------KLHEGDELRISAVVEAYP 3295
+SG + + ++ + V G P+ ++ EG L + VV
Sbjct: 2795 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQA 2854
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
VTW++ G L P+R + G + L L V+ D+G Y+C + G S
Sbjct: 2855 HAQVTWHKRGGNL-PARHQV-----HGPL-LRLNQVSPADSGEYSCQVTGSSGTLEASVL 2907
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T EP P + +P + +P++I + SS EG T+ + C V G V
Sbjct: 2908 V-------TIEPSSPGPIPAPGLA---QPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQV 2956
Query: 3416 YWLR 3419
W +
Sbjct: 2957 TWYK 2960
Score = 60.5 bits (140), Expect = 1e-07
Identities = 92/366 (25%), Positives = 135/366 (36%), Gaps = 70/366 (19%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L + AG TA L CS G P P + W K + + R+ L I + D
Sbjct: 3220 ELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQH-RLEGD------TLIIPRVAQQD 3272
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y C AT+ G A L V + PP T
Sbjct: 3273 SGQYICNATSPAGHAEATIILHV-----------------------ESPPYATTVPEHAS 3309
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
VQA V+L C G+PP W + G + R ++E H AP +D G Y
Sbjct: 3310 VQAGETVQLQCLAHGTPPLTFQWSRVGSSL---PGRATARNELLHFERAAP---EDSGRY 3363
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR-ISAVVE---AY 3294
N G+ L+V + A G P ++ E + I A VE A
Sbjct: 3364 RCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAV 3423
Query: 3295 PS---VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
PS + W+++G +L P +DG L + + G Y C A G+A
Sbjct: 3424 PSDQGTQLRWFKEGGQLPPGHSV-----QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQ 3476
Query: 3352 TSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S ++ + +P V+I ++ S + + + G V EC +GDP
Sbjct: 3477 ASAQLVI--------QALPSVLI--NIRTSVQTVVV----------GHAVEFECLALGDP 3516
Query: 3412 KPDVYW 3417
KP V W
Sbjct: 3517 KPQVTW 3522
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/372 (22%), Positives = 134/372 (36%), Gaps = 54/372 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P ++ G+T +L C V G+ V W K G G + + L +
Sbjct: 2343 IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG-------GSLPVRHQTHGSLLRLY 2395
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG-DYPPQFT 3171
+ D G Y C V+ EA + E + V P
Sbjct: 2396 QASPADSGEYVCR---------------VLGSSVPLEASVLVTIEPAGSVPALGVTPTVR 2440
Query: 3172 MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
+ +V + L C V G +V+W+K G + R++ + L++ P
Sbjct: 2441 IESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL---PARHQVHGSRLRLLQVTPA- 2496
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRIS 3288
D G Y +SG + + + + + + L G L ++
Sbjct: 2497 --DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLN 2554
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+V + +TWY+ G L PSR I+ G L + VT D+G Y C SN G
Sbjct: 2555 CLVASQAPHTITWYKRGGSL-PSRHQIV-----GS-RLRIPQVTPADSGEYVCHVSNGAG 2607
Query: 3349 RASTSGKVEVIGTDQTSEPRI-PPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
TS V + G+ + P + PP+ I S P + EG T+ + C V
Sbjct: 2608 SRETSLIVTIQGSGSSHVPSVSPPIRIE-----SSSPTVV---------EGQTLDLNCVV 2653
Query: 3408 VGDPKPDVYWLR 3419
P+ + W +
Sbjct: 2654 ARQPQAIITWYK 2665
Score = 58.8 bits (136), Expect = 3e-07
Identities = 75/327 (22%), Positives = 119/327 (36%), Gaps = 40/327 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET +L C V G+ V W K G G + S L + ++ D G
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRG-------GSLPSHHQTRGSRLRLHHVSPADSGE 2790
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C + G + + +A G PP + RV
Sbjct: 2791 YVCRVMGSSGPLEASVLVTI---------EASGSSAVHVPAPGGAPP-IRIEPSSSRVAE 2840
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ +++P D G Y
Sbjct: 2841 GQTLDLKCVVPGQAHAQVTWHKRGGNL---PARHQVHGPLLRLNQVSPA---DSGEYSCQ 2894
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLY------KLHEGDELRISAVVEAY 3294
+SG + + ++ + AP +P+Y + EG L ++ VV
Sbjct: 2895 VTGSSGTLEASVLVTIEPSSPGPIPAPGLA---QPIYIEASSSHVTEGQTLDLNCVVPGQ 2951
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
VTWY+ G L P+R Q+ L L V+ D+G Y C A++ G +
Sbjct: 2952 AHAQVTWYKRGGSL-PARHQT----HGSQLRLHL--VSPADSGEYVCRAASGPGPEQEAS 3004
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ + S R+ VIS D P S
Sbjct: 3005 FTVTVPPSEGSSYRLRSPVISIDPPSS 3031
Score = 58.4 bits (135), Expect = 4e-07
Identities = 91/385 (23%), Positives = 140/385 (36%), Gaps = 44/385 (11%)
Query: 3034 SSQTSSSIGVGLAGDR-PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE 3092
++Q + V A D P V I + G+T +L C V G V W + G +
Sbjct: 2033 TAQARMQVVVLSASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP 2092
Query: 3093 EEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADA 3152
+Q +G L + ++ D G Y C N G ++V+
Sbjct: 2093 PH-----TQVHGSR--LRLPQVSPADSGEYVCRVENGSGPKEASITVSVL--------HG 2137
Query: 3153 KLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
V G P + V + L C V G +V+W+K G +
Sbjct: 2138 THSGPSYTPVPGSTRP-IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSL---P 2193
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG 3272
R++ ++ P D G Y SG + + ++ + P
Sbjct: 2194 ARHQTHGSLLRLHQVTPA---DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIE 2250
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
+ EG L +S VV VTWY+ G L P+R + R ++ + A+
Sbjct: 2251 SSSS-TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL-PARHQV----RGSRLYIFQASPA 2304
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
DAG Y C ASN + + T V V GT Q + P S +P+ I +P S
Sbjct: 2305 --DAGQYVCRASNGMEASIT---VTVTGT-QGANLAYPAG--------STQPIRI-EPSS 2349
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYW 3417
S+ EG T+ + C V G V W
Sbjct: 2350 SQVAEGQTLDLNCVVPGQSHAQVTW 2374
Score = 58.0 bits (134), Expect = 6e-07
Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 54/401 (13%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKILAGETANLTCSVKGKPV 3079
+R N YG +S V L+ P V +LP G + + G+ L C G+P
Sbjct: 3089 YRCVASNAYGVAQSV-------VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPR 3141
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
W + + + T L I D G Y C A N G A +
Sbjct: 3142 SSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3200
Query: 3140 AVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKV 3199
V T A G PQ + V+A + L C GSP P +
Sbjct: 3201 IVDT---------------GAMAPG--APQVQAEEAELTVEAGHTATLRCSATGSPAPTI 3243
Query: 3200 SWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK 3259
W K + + R + TL I D G Y A + +G L V+
Sbjct: 3244 HWSKLRSPLPWQHRL------EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVES 3297
Query: 3260 GIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD 3319
A PE + G+ +++ + P + W R G L P R
Sbjct: 3298 PPYATTVPEHA-------SVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATA---- 3345
Query: 3320 RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVP 3379
R+ + AA D+G Y C +N+VG A ++ V G P + + +P
Sbjct: 3346 RNELLHFERAA--PEDSGRYRCRVTNKVGSAEAFAQLLVQGP--------PGSLPATSIP 3395
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+ G +V C V D + W ++
Sbjct: 3396 AGSTPTVQVTPQLETKSIGASVEFHCAVPSDQGTQLRWFKE 3436
Score = 58.0 bits (134), Expect = 6e-07
Identities = 73/313 (23%), Positives = 114/313 (36%), Gaps = 50/313 (15%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF 3105
AG P V + P G + C+V + W K G G++ +
Sbjct: 3396 AGSTPT-VQVTPQLETKSIGASVEFHCAVPSDQGTQLRWFKEG-------GQLPPGHSVQ 3447
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
D L I++++ +G Y C+A GKA A+L + +V
Sbjct: 3448 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL----------------- 3490
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
+R + V + V C +G P P+V+W K G + R Q +
Sbjct: 3491 ----INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL----RPGIVQSGG--VV 3540
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
IA L D G Y TA N +G H L+V P+ E ++ G
Sbjct: 3541 RIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ------ALPQISMPQE--VRVPAGSAA 3592
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ YP+ ++W + L P R + L L +V +DAG Y CTA+N
Sbjct: 3593 VFPCIASGYPTPDISWSKLDGSLPPDSRLENNM-------LMLPSVRPQDAGTYVCTATN 3645
Query: 3346 EVGRASTSGKVEV 3358
G+ ++V
Sbjct: 3646 RQGKVKAFAHLQV 3658
Score = 56.8 bits (131), Expect = 1e-06
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 21/184 (11%)
Query: 2594 PVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P ++T + + +V+ G V+L C + T W R G L + R +L L
Sbjct: 3298 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LH 3351
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
A P DS Y C V N+ G+ A L V S A+ IP T +++ T L
Sbjct: 3352 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3411
Query: 2710 EL----VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ C + ++ WFK+ Q+P Q DGV R I N GTY
Sbjct: 3412 SIGASVEFHCAVPSDQGTQLRWFKEGGQLPPGHSVQ-----DGVLR--IQNLDQSCQGTY 3464
Query: 2766 TCKA 2769
C+A
Sbjct: 3465 ICQA 3468
Score = 56.4 bits (130), Expect = 2e-06
Identities = 87/368 (23%), Positives = 138/368 (37%), Gaps = 54/368 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P + G+T +L C V G+ V W K G G + ++ L +
Sbjct: 2154 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRG-------GSLPARHQTHGSLLRLH 2206
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D G Y C T G A + V + +V + G PP +
Sbjct: 2207 QVTPADSGEYVCHVVGTSGPLE--ASVLVTIEASV--------------IPGPIPP-VRI 2249
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L+C V G +V+WYK G + R++ + + + + +P
Sbjct: 2250 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL---PARHQVRGSRLYIFQASPA-- 2304
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIR-AYVAPEFC-CGLEPLY-KLHEGDELRISA 3289
D G Y A N A S + +G AY A +EP ++ EG L ++
Sbjct: 2305 -DAGQYVCRASNGMEA-SITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 2362
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTW++ G L P R G + L L + D+G Y C V
Sbjct: 2363 VVPGQSHAQVTWHKRGGSL-PVRH-----QTHGSL-LRLYQASPADSGEYVC----RVLG 2411
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+S + V+ T + + +P + ++P V SS+ EG T+ + C V G
Sbjct: 2412 SSVPLEASVLVTIEPAGS-VPALGVTPTVRIESS--------SSQVAEGQTLDLNCLVAG 2462
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 2463 QAHAQVTW 2470
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 17/212 (8%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
R PV S T +G C + + P ++ W L++ + +IT
Sbjct: 3020 RSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPN--GSIIT 3077
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAE 2708
++ PS+ Y C N G + NL V+ P+ P P + +
Sbjct: 3078 --IVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--------VG 3127
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ LEC G+P W + P+ + + L D L I + P D+GTY C
Sbjct: 3128 KAVTLECVSAGEPRSSARWTRISST-PAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3186
Query: 2769 AENSVWTDQ-ITHFVNFTGRESQVSPNVVTAE 2799
A+N++ T Q + TG + +P V E
Sbjct: 3187 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE 3218
Score = 55.6 bits (128), Expect = 3e-06
Identities = 74/311 (23%), Positives = 115/311 (36%), Gaps = 42/311 (13%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV S T G + CS S PT+ W +L + ++ G++ L
Sbjct: 1866 PVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGP---GGQLPAKAQIHGGILRLPA 1922
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ P+D A+Y C + G A L V+ P R H A + L
Sbjct: 1923 VE--PTDQAQYLCRAHSSAGQQVARAVLHVH----GGGGPRVQVSPERTQVH-AGRTVRL 1975
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
CR G P ITW K+ +P R + + L I T D+G Y C A +
Sbjct: 1976 YCRAAGVPSATITWRKEGGSLPPQARSE----RTDIATLLIPAITTADAGFYLCVATSPA 2031
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
T Q +++ V++A +ES P V G T+ L
Sbjct: 2032 GTAQ-----------ARMQVVVLSASDASPPGVKIESSSP---------SVTEGQTLDLN 2071
Query: 2834 VEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
+ G +V W R G S+ + +V + L L V+ +SG Y CR + G
Sbjct: 2072 CVVAGSAHAQVTWYRRGGSLPP---HTQVHGSR----LRLPQVSPADSGEYVCRVENGSG 2124
Query: 2893 NVDMNAAITVV 2903
+ + ++V+
Sbjct: 2125 PKEASITVSVL 2135
Score = 54.8 bits (126), Expect = 5e-06
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 21/169 (12%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+T V G V+ C + P VTW + G L R +V + + + +D+
Sbjct: 3498 QTVVVGHAVEFECLALGDPKPQVTWSKVGGHL------RPGIVQSGGVVRIAHVELADAG 3551
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y CT N G + L V +A P + + +R A + V C G P
Sbjct: 3552 QYRCTATNAAGTTQSHVLLLV----QALP-QISMPQEVRVP---AGSAAVFPCIASGYPT 3603
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
P I+W K D +P D R L + + L + + P+D+GTY C A N
Sbjct: 3604 PDISWSKLDGSLPPDSR-----LENNM--LMLPSVRPQDAGTYVCTATN 3645
Score = 53.6 bits (123), Expect = 1e-05
Identities = 85/358 (23%), Positives = 126/358 (35%), Gaps = 50/358 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G+ V W K G G + ++ L + ++ D G
Sbjct: 2936 VTEGQTLDLNCVVPGQAHAQVTWYKRG-------GSLPARHQTHGSQLRLHLVSPADSGE 2988
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A + G A V TV ++ R RS + D PP T VQ
Sbjct: 2989 YVCRAASGPGPEQE-ASFTV----TVPPSEGSSYRLRSPVISID-PPSST-------VQQ 3035
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
C + G+ P + W +E+ N + + I T + G Y
Sbjct: 3036 GQDASFKCLIHDGAAPISLEWKTRNQEL----EDNVHISPNGSIITIVGTRPSNHGTYRC 3091
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N G L V V PE P++ + G + + V P
Sbjct: 3092 VASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVW-VKVGKAVTLECVSAGEPRSSAR 3145
Query: 3301 WYRDGVRLRPSRRAIMTLD-RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
W R + P++ T D L +++ DAG Y C A N +G A +VEVI
Sbjct: 3146 WTR--ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK--QVEVI 3201
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P P V ++E + EA G T + C G P P ++W
Sbjct: 3202 VDTGAMAPGAPQV-------QAEEAEL-----TVEA--GHTATLRCSATGSPAPTIHW 3245
Score = 53.6 bits (123), Expect = 1e-05
Identities = 74/359 (20%), Positives = 129/359 (35%), Gaps = 45/359 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L CS S PT+ W + L + L ++ +L TL + DS +
Sbjct: 3222 TVEAGHTATLRCSATGSPAPTIHWSK----LRSPLPWQHRLEGD--TLIIPRVAQQDSGQ 3275
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C + G + L V A+ +P + +T L +C G P
Sbjct: 3276 YICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL-------QCLAHGTPPL 3328
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W + +P GR A L + PEDSG Y C+ N V + + +
Sbjct: 3329 TFQWSRVGSSLP--GRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3381
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
G + + A T + + + G ++ A G T++
Sbjct: 3382 VQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG-ASVEFHCAVPSDQG---------TQL 3431
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +EG + + V+ G+ L + ++ ++ G Y C+A G +A + +
Sbjct: 3432 RWFKEGGQLPPGHS-----VQDGV--LRIQNLDQSCQGTYICQAHGPWGKAQASAQLVI- 3483
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPG--EPCVVDGG 2960
P+V++ + VG + G+PKP+ ++ G P +V G
Sbjct: 3484 -----QALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG 3537
Score = 47.2 bits (107), Expect = 0.001
Identities = 47/185 (25%), Positives = 69/185 (37%), Gaps = 18/185 (9%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L CQV GSPP W ++ V + ++Q + H + P+ D GVY T RN
Sbjct: 1696 LRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPS---DAGVYICTCRNLH 1752
Query: 3247 GAVSCHCGLVV----DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWY 3302
+ + L+V K I V + + P D I P+ + W
Sbjct: 1753 QSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP-----GADVTFICTAKSKSPAYTLVW- 1806
Query: 3303 RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTD 3362
RL + +D +G L + V DAG Y CT SN + + V +
Sbjct: 1807 ---TRLHNGKLPTRAMDFNG--ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASG 1861
Query: 3363 QTSEP 3367
S P
Sbjct: 1862 TLSAP 1866
Score = 47.2 bits (107), Expect = 0.001
Identities = 75/360 (20%), Positives = 128/360 (35%), Gaps = 35/360 (9%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SS++ V G P + I P ++ G+T +L C V G+ V W K G G
Sbjct: 2815 SSAVHVPAPGGAPP-IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRG-------GN 2866
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ ++ L + ++ D G YSC+ T G + T +VT +
Sbjct: 2867 LPARHQVHGPLLRLNQVSPADSGEYSCQVT---GSSGTLEASVLVT--------IEPSSP 2915
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
G P + + V + L C V G +V+WYK G + R++
Sbjct: 2916 GPIPAPGLAQPIY-IEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL---PARHQT 2971
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSG---AVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
Q ++P D G Y A + G S + +G +
Sbjct: 2972 HGSQLRLHLVSPA---DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDP 3028
Query: 3275 PLYKLHEGDELRISAVV-EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
P + +G + ++ + + + W L + + + +G I + +
Sbjct: 3029 PSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VHISPNGSI-ITIVGTRP 3083
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
+ G Y C ASN G A + + V G S PV + + E + +PRSS
Sbjct: 3084 SNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSS 3143
Score = 46.0 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+T TC G P P + W N + R+T G L I+D+ D+G Y+C
Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHP-RVTVTSEGGRGTLIIRDVKESDQGAYTC 479
Query: 3125 EATNTHG 3131
EA N G
Sbjct: 480 EAMNARG 486
Score = 42.3 bits (95), Expect = 0.030
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 18/170 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ V+ C+V S + W++ G +L + DG++ ++ L+ S Y C
Sbjct: 3414 GASVEFHCAVPSDQGTQLRWFKEG----GQLPPGHSVQDGVLRIQNLDQ--SCQGTYICQ 3467
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
G SA L + +A P R+ T + + + EC G P P++TW
Sbjct: 3468 AHGPWGKAQASAQLVI----QALPSVLINIRTSVQTV-VVGHAVEFECLALGDPKPQVTW 3522
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K + G Q+ GV R+A + D+G Y C A N+ T Q
Sbjct: 3523 SKVGGHL-RPGIVQS----GGVVRIA--HVELADAGQYRCTATNAAGTTQ 3565
Score = 39.9 bits (89), Expect = 0.16
Identities = 53/234 (22%), Positives = 78/234 (33%), Gaps = 40/234 (17%)
Query: 3031 WGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
WG++ ++ + L ++I ++ G C G P P V W K G
Sbjct: 3472 WGKAQASAQLVIQALPS---VLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH 3528
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
+ Q G + I + + D G+Y C ATN G ++ L V
Sbjct: 3529 LRPGI----VQSGGV---VRIAHVELADAGQYRCTATNAAGTTQSHVLLLV--------- 3572
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
PQ +M ++ RV A C G P P +SW K +
Sbjct: 3573 --------------QALPQISMP-QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPP 3617
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
D R + L + D G Y TA N G V L V + + Y
Sbjct: 3618 DSRLEN------NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPY 3665
Score = 38.3 bits (85), Expect = 0.48
Identities = 24/72 (33%), Positives = 32/72 (44%)
Query: 2823 QVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
Q +RG T+ G PT + R + V E G TL + DV E++ G
Sbjct: 417 QASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGA 476
Query: 2883 YTCRAWSAHGNV 2894
YTC A +A G V
Sbjct: 477 YTCEAMNARGMV 488
Score = 34.7 bits (76), Expect = 5.9
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 10/105 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
GS C P ++W + LD L +L + ++ L + P D+ Y CT
Sbjct: 3589 GSAAVFPCIASGYPTPDISWSK----LDGSLPPDSRLENNMLMLPSVR--PQDAGTYVCT 3642
Query: 2668 VENENGAISTSANL----KVYPSFEASPIPPTFTRSIRDTFHLAE 2708
N G + A+L +V P F +P +I+D + E
Sbjct: 3643 ATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFE 3687
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1b protein.
Length = 1842
Score = 81.4 bits (192), Expect = 5e-14
Identities = 97/378 (25%), Positives = 145/378 (38%), Gaps = 66/378 (17%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RPE V G ++ L C+ G P+P + W+K+G + ++ R T + G
Sbjct: 17 RPEDV----GTSLYFVNDSLQLPCTAPGYPIPAIRWLKDGRPLPADS-RWTKRITG---- 67
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
LTI D+ +D G Y CE TNT G A L V+ V KLK
Sbjct: 68 LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLK------------- 114
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIA 3228
+ +T V L+C + GSP + WY++ E V+ D+ + + TL I
Sbjct: 115 --------TGIGST--VILSCALTGSPEFTIRWYRNTELVLPDEAIS-IRGLSNETLLIT 163
Query: 3229 PTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS 3288
G Y+ A + + ++ G V+ F E + ++ G++ +
Sbjct: 164 SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVS-SFS---EKV--VNPGEQFSLM 217
Query: 3289 AVVEAYPSVGVTWYRDG---VRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCTAS 3344
+ P VTW D VR R T+ I + + RD GVY CTA
Sbjct: 218 CAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTAR 277
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
N VG A ++ V G P IR R+ A G +I
Sbjct: 278 NLVGSAEYQARINVRG-----------------------PPSIRAMRNITAVAGRDTLIN 314
Query: 3405 CEVVGDPKPDVYWLRDFL 3422
C V+G P + W +D L
Sbjct: 315 CRVIGYPYYSIKWYKDAL 332
Score = 66.9 bits (156), Expect = 1e-09
Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V L+C++ S + T+ WYRN VL D + R + TL + +A S S Y
Sbjct: 118 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNE---TLLITSAQKSHSGAYQ 174
Query: 2666 CTVENENGAISTSANLKVYPSFEASP-IPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
C + T+ + + + +P I +F+ + + + L C +G P P
Sbjct: 175 CFATRK---AQTAQDFAIIALEDGTPRIVSSFSEKVVN----PGEQFSLMCAAKGAPPPT 227
Query: 2725 ITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPTPEDSGTYTCKAENSVWTDQITH 2780
+TW DD+ I DG R + ++DG + + + P D G Y C A N V + +
Sbjct: 228 VTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA 287
Query: 2781 FVNFTGRESQVSPNVVTA 2798
+N G S + +TA
Sbjct: 288 RINVRGPPSIRAMRNITA 305
Score = 65.3 bits (152), Expect = 4e-09
Identities = 99/384 (25%), Positives = 151/384 (39%), Gaps = 55/384 (14%)
Query: 2965 SLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVT 3024
SL P + P P + + + + A+ +RW + IT L D G Y VT
Sbjct: 31 SLQLPCTAPGYPIPAIRWLKDGRPLPAD--SRWTKR-ITGLTISDLRTEDSGT-YICEVT 86
Query: 3025 PRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW 3084
N +G E++ G+ + D P V + P +LK G T L+C++ G P + W
Sbjct: 87 --NTFGSAEAT------GILMVID-PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW 137
Query: 3085 MKNGHEV-EEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVT 3143
+N V +EA + N L I G Y C AT KA T A++
Sbjct: 138 YRNTELVLPDEAISIRGLSNE---TLLITSAQKSHSGAYQCFATR---KAQTAQDFAIIA 191
Query: 3144 DRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYK 3203
+E D P+ ++ V L C G+PPP V+W
Sbjct: 192 ------------------LE-DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWAL 232
Query: 3204 DGEEVVYD--KRRNKYQDEQFHT---LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
D E +V D R N+Y T + + + DGGVY TARN G+ + V
Sbjct: 233 DDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV- 291
Query: 3259 KGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL 3318
+G P + + + D L I+ V YP + WY+D + L + R ++
Sbjct: 292 RG------PPSIRAMRNITAVAGRDTL-INCRVIGYPYYSIKWYKDALLLPDNHRQVVF- 343
Query: 3319 DRDGQIELALAAVTTRDAGVYTCT 3342
+G ++L D G Y C+
Sbjct: 344 -ENGTLKLT-DVQKGMDEGEYLCS 365
Score = 58.8 bits (136), Expect = 3e-07
Identities = 64/262 (24%), Positives = 105/262 (40%), Gaps = 45/262 (17%)
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDS 2762
+ + + L L C G P+P I W KD + +P+D R+ + L I + EDS
Sbjct: 24 SLYFVNDSLQLPCTAPGYPIPAIRWLKDGRPLPADSRW-----TKRITGLTISDLRTEDS 78
Query: 2763 GTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDY 2822
GTY C+ N+ + + TG + P VT ++
Sbjct: 79 GTYICEVTNTFGSAEA------TGILMVIDPLHVTLTPKKL------------------- 113
Query: 2823 QVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGL--YTLALSDVTETE 2879
+ G T+ L + G P + W R TE+ +GL TL ++ ++
Sbjct: 114 KTGIGSTVILSCALTGSPEFTIRWYRN----TELVLPDEAISIRGLSNETLLITSAQKSH 169
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQG 2939
SG Y C A + + AI ++ DG P ++ EK +++ GE ++ +G
Sbjct: 170 SGAYQCFA-TRKAQTAQDFAIIALE----DGTPRIVSSFSEK--VVNPGEQFSLMCAAKG 222
Query: 2940 EPKPKAVPERIPGEPCVVDGGN 2961
P P V + EP V DG +
Sbjct: 223 AP-PPTVTWALDDEPIVRDGSH 243
Score = 55.2 bits (127), Expect = 4e-06
Identities = 80/363 (22%), Positives = 138/363 (38%), Gaps = 49/363 (13%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG--VLLDNKLKYRKKLVDGLITLE 2652
+ S+F +++ G + L C+ + PTVTW + ++ D + + + T+
Sbjct: 199 IVSSF-SEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 257
Query: 2653 VLNAV-PS--DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+N P D Y CT N G+ A + V PP+ R++R+ +A
Sbjct: 258 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG-------PPSI-RAMRNITAVAGR 309
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ ++ CR+ G P I W+KD +P + R F +G +L D D G Y C
Sbjct: 310 DTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--ENGTLKLT-DVQKGMDEGEYLCSV 366
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
+ +S +V A K Q E G +L V G
Sbjct: 367 --------------LIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGD 412
Query: 2830 IGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWS 2889
+ P R+ W ++G+ + + ++ + +L +S V+ +G TC A +
Sbjct: 413 M---------PIRITWRKDGQVIIS-GSGVTIESKEFMSSLQISSVSLKHNGNDTCIASN 462
Query: 2890 AHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPER 2949
A V + V P P +V +D + +N S G P PK + +
Sbjct: 463 AAATVSRERQLIVRVP------PRFVVQPNNQDGIYGKAGVLNCS--VDGYPPPKVMWKH 514
Query: 2950 IPG 2952
G
Sbjct: 515 AKG 517
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 3/130 (2%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
+L +G++Y V G G SS+ + + AG P + G + + L
Sbjct: 1043 HLNRGQQYLLWVAAVTSAGRGNSSE---KVTIEPAGKAPAKIISFGGTVTTPWMKDVRLP 1099
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C+ G P P V W K+ + + + L ++ + +D G Y+C ATNT G
Sbjct: 1100 CNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGG 1159
Query: 3132 KASTYARLAV 3141
+ L V
Sbjct: 1160 FDTIIVNLLV 1169
Score = 45.6 bits (103), Expect = 0.003
Identities = 51/205 (24%), Positives = 89/205 (43%), Gaps = 19/205 (9%)
Query: 2576 ARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD 2635
AR+++ +R + R P + + TAV G + C VI ++ WY++ +LL
Sbjct: 276 ARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLP 335
Query: 2636 NKLKYRKKLVDGLITLEVLNAVPS-DSAEYSCTV-ENENGAISTSAN--LKVYPSFEASP 2691
+ +++V TL++ + D EY C+V +IS S + +KV P +
Sbjct: 336 DN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFE 392
Query: 2692 IPPTFTRSIRDTFHLAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVC 2750
PP + L + C + +P +ITW KD + I S G + +
Sbjct: 393 FPPASIGQL----------LYIPCVVSSGDMPIRITWRKDGQVIIS-GSGVTIESKEFMS 441
Query: 2751 RLAIDNPTPEDSGTYTCKAENSVWT 2775
L I + + + +G TC A N+ T
Sbjct: 442 SLQISSVSLKHNGNDTCIASNAAAT 466
Score = 44.4 bits (100), Expect = 0.007
Identities = 41/175 (23%), Positives = 69/175 (39%), Gaps = 14/175 (8%)
Query: 2608 GSRVKLTCSVISSSDPT-VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
G + + C V S P +TW ++G ++ + + + + +L++ + + +C
Sbjct: 399 GQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTC 458
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
N +S L V +PP F + + VL C + G P PK+
Sbjct: 459 IASNAAATVSRERQLIVR-------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVM 511
Query: 2727 WFKDDKQIPSDGRYQAFYLADGV-----CRLAIDNPTPEDSGTYTCKAENSVWTD 2776
W K K + +Y L + L I + ED G Y C+A N V TD
Sbjct: 512 W-KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTD 565
Score = 41.1 bits (92), Expect = 0.068
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 11/160 (6%)
Query: 3193 GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCH 3252
G P +++W KDG+ ++ E +L+I+ +L G A N + VS
Sbjct: 411 GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRE 470
Query: 3253 CGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSR 3312
L+V R V P + +Y G ++ V+ YP V W P +
Sbjct: 471 RQLIVRVPPRFVVQPN---NQDGIY----GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 523
Query: 3313 RAIMTLDRDGQI----ELALAAVTTRDAGVYTCTASNEVG 3348
+ L QI L + V D G Y C ASN VG
Sbjct: 524 YHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 563
Score = 39.9 bits (89), Expect = 0.16
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLEIAPTNLDDGGVYEVTAR 3243
VRL C +G P P V W KD E+ + ++ + TL + +D G Y TA
Sbjct: 1096 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1155
Query: 3244 NNSG 3247
N G
Sbjct: 1156 NTGG 1159
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK---NGHEVEEEAGRMTSQFNGF- 3105
P FV + P + G+ L CSV G P P V+W +G+ + +T +
Sbjct: 479 PRFV-VQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILP 537
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHG 3131
+ L I+ + +D G Y C+A+N G
Sbjct: 538 NSSLLIRHVLEEDIGYYLCQASNGVG 563
Score = 35.1 bits (77), Expect = 4.5
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Query: 2713 LECRIRGQPLPKITWFKD--DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
L C G P P + W KD D IP +G L + EDSG YTC A
Sbjct: 1098 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT--LLLRAVKAEDSGYYTCTAT 1155
Query: 2771 NSVWTDQI 2778
N+ D I
Sbjct: 1156 NTGGFDTI 1163
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 81.4 bits (192), Expect = 5e-14
Identities = 91/357 (25%), Positives = 151/357 (42%), Gaps = 44/357 (12%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R ++ L+ L ++ P+DS EYSC
Sbjct: 780 EGQTLDLKCVVPGQAHAQVTWHKRG----GNLPARHQVHGPLLRLNQVS--PADSGEYSC 833
Query: 2667 TVENENGAISTSANLKVYPSFEASPIP-PTFTRSI---RDTFHLAENE-LVLECRIRGQP 2721
V +G + S + + PS PIP P + I + H+ E + L L C + GQ
Sbjct: 834 QVTGSSGTLEASVLVTIEPS-SPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQA 892
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
++TW+K +P+ R+Q +L + +P DSG Y C+A + +Q F
Sbjct: 893 HAQVTWYKRGGSLPA--RHQTH-----GSQLRLHLVSPADSGEYVCRAASGPGPEQEASF 945
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
V P+ ++ + R S++ P V Q + + + P
Sbjct: 946 T------VTVPPSEGSSYRLRSPVISID---PPSSTV----QQGQDASFKCLIHDGAAPI 992
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+EW + E+ N + + T+ + G Y C A +A+G A +
Sbjct: 993 SLEWKTRNQ---ELEDNVHISPNGSIITIV--GTRPSNHGTYRCVASNAYG-----VAQS 1042
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVVD 2958
VV S + G P V V PE + + VG+ + + + GEP+ A RI P ++
Sbjct: 1043 VVNLS-VHGPPTVSV-LPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLE 1097
Score = 80.2 bits (189), Expect = 1e-13
Identities = 85/321 (26%), Positives = 132/321 (41%), Gaps = 39/321 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T VEG + L C V +TWY+ G L R + + L ++ +DS E
Sbjct: 580 TVVEGQTLDLNCVVARQPQAIITWYKRG----GSLPSRHQTHGSHLRLHQMSV--ADSGE 633
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR---DTFHLAENE-LVLECRIRG 2719
Y C N A+ S + V PS SP P + IR + H+AE E L L C + G
Sbjct: 634 YVCRANNNIDALEASIVISVSPS-AGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 692
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
Q ++TW K +PS + + RL + + +P DSG Y C+ S + +
Sbjct: 693 QAHAQVTWHKRGGSLPSHHQTRG-------SRLRLHHVSPADSGEYVCRVMGSSGPLEAS 745
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG- 2838
V S I + SR VA G T+ L+ + G
Sbjct: 746 VLVTIEASGSSAVHVPAPGGAPPIRIEPSSSR------------VAEGQTLDLKCVVPGQ 793
Query: 2839 CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
+V W + G ++ AR V L L L+ V+ +SG Y+C+ + G ++ +
Sbjct: 794 AHAQVTWHKRGGNLP-----ARHQVHGPL--LRLNQVSPADSGEYSCQVTGSSGTLEASV 846
Query: 2899 AITVVQPSDLDGKPAVIVGRP 2919
+T ++PS PA + +P
Sbjct: 847 LVT-IEPSSPGPIPAPGLAQP 866
Score = 78.2 bits (184), Expect = 5e-13
Identities = 91/356 (25%), Positives = 147/356 (41%), Gaps = 46/356 (12%)
Query: 2570 SKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTA--VEGSRVKLTCSVISSSDPTVTW 2627
S EA +++ ++ LS + ++ + + +A G + L C V S + T+TW
Sbjct: 448 SSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITW 507
Query: 2628 YRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
Y+ G L R ++V L + P+DS EY C V N G+ TS + + S
Sbjct: 508 YKRG----GSLPSRHQIVGS--RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG 561
Query: 2688 EA---SPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
+ S PP S T + L L C + QP ITW+K +PS R+Q
Sbjct: 562 SSHVPSVSPPIRIESSSPTV-VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RHQTHG 618
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
L + + DSG Y C+A N++ D + + + S SP+ +
Sbjct: 619 -----SHLRLHQMSVADSGEYVCRANNNI--DALEASIVISVSPSAGSPSAPGSSMP--- 668
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFV 2863
+ES H VA G T+ L + G +V W + G S+ ++
Sbjct: 669 -IRIESSSSH---------VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQT----- 713
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRP 2919
+G L L V+ +SG Y CR + G ++ + +T+ + G AV V P
Sbjct: 714 -RG-SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI----EASGSSAVHVPAP 763
Score = 74.9 bits (176), Expect = 5e-12
Identities = 78/298 (26%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V + VTW++ G L R + L+ L P+DS EY C
Sbjct: 105 EGQTLDLNCVVPGQAHAQVTWHKRG----GSLPARHQTHGSLLRLH--QVTPADSGEYVC 158
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKI 2725
V +G + S + + S PIPP S T +AE + L L C + GQ ++
Sbjct: 159 HVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSST--VAEGQTLDLSCVVAGQAHAQV 216
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT 2785
TW+K +P+ R+Q RL I +P D+G Y C+A N
Sbjct: 217 TWYKRGGSLPA--RHQV-----RGSRLYIFQASPADAGQYVCRASN-------------- 255
Query: 2786 GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTRVE 2844
G E+ ++ V + +A + S +P + QVA G T+ L + G +V
Sbjct: 256 GMEASITVTVTGTQGANLAYPA-GSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT 313
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
W + G S+ ++ G L L + +SG Y CR + ++ + +T+
Sbjct: 314 WHKRGGSLPVRHQT------HG-SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 364
Score = 68.9 bits (161), Expect = 3e-10
Identities = 82/312 (26%), Positives = 124/312 (39%), Gaps = 41/312 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
EG + L C V S VTW++ G L R + L+ L A P+DS EY C
Sbjct: 294 EGQTLDLNCVVPGQSHAQVTWHKRG----GSLPVRHQTHGSLLRL--YQASPADSGEYVC 347
Query: 2667 TVENENGAISTSANLKVYP--SFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLP 2723
V + + S + + P S A + PT R + +AE + L L C + GQ
Sbjct: 348 RVLGSSVPLEASVLVTIEPAGSVPALGVTPT-VRIESSSSQVAEGQTLDLNCLVAGQAHA 406
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW K +P+ R+Q RL + TP DSG Y C+ S T + + V
Sbjct: 407 QVTWHKRGGSLPA--RHQVH-----GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVT 459
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG-CPTR 2842
R S S + A RI S +A G T+ L + P
Sbjct: 460 IQQRLSG-SHSQGVAYPVRIESSSA--------------SLANGHTLDLNCLVASQAPHT 504
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
+ W + G S+ ++ L + VT +SG Y C + G+ + + +T
Sbjct: 505 ITWYKRGGSLPSRHQIVG-------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVT- 556
Query: 2903 VQPSDLDGKPAV 2914
+Q S P+V
Sbjct: 557 IQGSGSSHVPSV 568
Score = 68.5 bits (160), Expect = 4e-10
Identities = 87/309 (28%), Positives = 130/309 (42%), Gaps = 56/309 (18%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
+ EG + L C V S+ VTWYR G L + V G L + P+DS E
Sbjct: 1 SVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQ-----VHG-SRLRLPQVSPADSGE 54
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASP--IP-PTFTRSIR---DTFHLAENE-LVLECR 2716
Y C VEN +G S + V + P P P TR IR + H+AE + L L C
Sbjct: 55 YVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCV 114
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
+ GQ ++TW K +P+ R+Q L + TP DSG Y C +
Sbjct: 115 VPGQAHAQVTWHKRGGSLPA--RHQTH-----GSLLRLHQVTPADSGEYVCHVVGTSGPL 167
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
+ + V E+ V P + + +ES + VA G T+ L +
Sbjct: 168 EASVLVTI---EASVIPGPIPPVR-------IES---------SSSTVAEGQTLDLSCVV 208
Query: 2837 RG-CPTRVEWLREGRSVTEVY--RNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
G +V W + G S+ + R +R+++ Q + ++G Y CRA ++G
Sbjct: 209 AGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ---------ASPADAGQYVCRA--SNG- 256
Query: 2894 VDMNAAITV 2902
M A+ITV
Sbjct: 257 --MEASITV 263
Score = 62.1 bits (144), Expect = 3e-08
Identities = 87/356 (24%), Positives = 128/356 (35%), Gaps = 46/356 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G T +L C V + + W K G G + S+ L I + D G Y C
Sbjct: 488 GHTLDLNCLVASQAPHTITWYKRG-------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 540
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+N G T +VT ++ S+ V PP + V
Sbjct: 541 HVSNGAGSRETSL---IVT----------IQGSGSSHVPSVSPP-IRIESSSPTVVEGQT 586
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+ L C V P ++WYK G + +++Q H L + ++ D G Y A N
Sbjct: 587 LDLNCVVARQPQAIITWYKRGGSLP-----SRHQTHGSH-LRLHQMSVADSGEYVCRANN 640
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRISAVVEAYPSVGVTW 3301
N A+ + V + AP + + EG+ L ++ VV VTW
Sbjct: 641 NIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTW 700
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
++ G L PS G L L V+ D+G Y C G S V I
Sbjct: 701 HKRGGSL-PSHHQTR-----GS-RLRLHHVSPADSGEYVCRVMGSSGPLEASVLV-TIEA 752
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
+S +P P P+ I +P SS EG T+ ++C V G V W
Sbjct: 753 SGSSAVHVP-------APGGAPPIRI-EPSSSRVAEGQTLDLKCVVPGQAHAQVTW 800
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/310 (27%), Positives = 121/310 (39%), Gaps = 51/310 (16%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG + L+C V + VTWY+ G L + + R L + A P+D+ +
Sbjct: 195 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGS------RLYIFQASPADAGQ 248
Query: 2664 YSCTVENENGAIST-------SANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLEC 2715
Y C N A T ANL YP+ PI R + +AE + L L C
Sbjct: 249 YVCRASNGMEASITVTVTGTQGANL-AYPAGSTQPI-----RIEPSSSQVAEGQTLDLNC 302
Query: 2716 RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
+ GQ ++TW K +P R+Q + RL +P DSG Y C+ S +
Sbjct: 303 VVPGQSHAQVTWHKRGGSLPV--RHQTH---GSLLRLY--QASPADSGEYVCRVLGS--S 353
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ V T + P + RI S QVA G T+ L
Sbjct: 354 VPLEASVLVTIEPAGSVPALGVTPTVRIESSS--------------SQVAEGQTLDLNCL 399
Query: 2836 IRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
+ G +V W + G S+ AR V L L VT +SG Y CR + G
Sbjct: 400 VAGQAHAQVTWHKRGGSLP-----ARHQVHGS--RLRLLQVTPADSGEYVCRVVGSSGTQ 452
Query: 2895 DMNAAITVVQ 2904
+ + +T+ Q
Sbjct: 453 EASVLVTIQQ 462
Score = 61.3 bits (142), Expect = 6e-08
Identities = 92/366 (25%), Positives = 134/366 (36%), Gaps = 70/366 (19%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+L + AG TA L CS G P P + W K + Q+ L I + D
Sbjct: 1160 ELTVEAGHTATLRCSATGSPAPTIHWSKL-------RSPLPWQYRLEGDTLIIPRVAQQD 1212
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
G+Y C AT+ G A L V + PP T
Sbjct: 1213 SGQYICNATSPAGHAEATIILHV-----------------------ESPPYATTVPEHAS 1249
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
VQA V+L C G+PP W + G + R ++E H AP +D G Y
Sbjct: 1250 VQAGETVQLQCLAHGTPPLTFQWSRVGSSL---PGRATARNELLHFERAAP---EDSGRY 1303
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR-ISAVVE---AY 3294
N G+ L+V + A G P ++ E + I A VE A
Sbjct: 1304 RCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAV 1363
Query: 3295 PS---VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
PS + W+++G +L P +DG L + + G Y C A G+A
Sbjct: 1364 PSDRGTQLRWFKEGGQLPPGHSV-----QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQ 1416
Query: 3352 TSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
S ++ + +P V+I ++ S + + + G V EC +GDP
Sbjct: 1417 ASAQLVI--------QALPSVLI--NIRTSVQTVVV----------GHAVEFECLALGDP 1456
Query: 3412 KPDVYW 3417
KP V W
Sbjct: 1457 KPQVTW 1462
Score = 60.9 bits (141), Expect = 8e-08
Identities = 80/364 (21%), Positives = 135/364 (37%), Gaps = 50/364 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++ G+T +L C V +P + W K G G + S+ L + +++ D G
Sbjct: 581 VVEGQTLDLNCVVARQPQAIITWYKRG-------GSLPSRHQTHGSHLRLHQMSVADSGE 633
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A N ++V S G P + V
Sbjct: 634 YVCRANNNIDALEASIVISVSPSAG------------SPSAPGSSMP-IRIESSSSHVAE 680
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + ++ + + ++P D G Y
Sbjct: 681 GETLDLNCVVPGQAHAQVTWHKRGGSL---PSHHQTRGSRLRLHHVSPA---DSGEYVCR 734
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY------KLHEGDELRISAVVEAYP 3295
+SG + + ++ + V G P+ ++ EG L + VV
Sbjct: 735 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQA 794
Query: 3296 SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
VTW++ G L P+R + G + L L V+ D+G Y+C + G S
Sbjct: 795 HAQVTWHKRGGNL-PARHQV-----HGPL-LRLNQVSPADSGEYSCQVTGSSGTLEASVL 847
Query: 3356 VEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDV 3415
V T EP P + +P + +P++I + SS EG T+ + C V G V
Sbjct: 848 V-------TIEPSSPGPIPAPGLA---QPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQV 896
Query: 3416 YWLR 3419
W +
Sbjct: 897 TWYK 900
Score = 59.3 bits (137), Expect = 2e-07
Identities = 82/372 (22%), Positives = 134/372 (36%), Gaps = 54/372 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P ++ G+T +L C V G+ V W K G G + + L +
Sbjct: 283 IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG-------GSLPVRHQTHGSLLRLY 335
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEG-DYPPQFT 3171
+ D G Y C V+ EA + E + V P
Sbjct: 336 QASPADSGEYVCR---------------VLGSSVPLEASVLVTIEPAGSVPALGVTPTVR 380
Query: 3172 MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTN 3231
+ +V + L C V G +V+W+K G + R++ + L++ P
Sbjct: 381 IESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL---PARHQVHGSRLRLLQVTPA- 436
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLE---PLYKLHEGDELRIS 3288
D G Y +SG + + + + + + L G L ++
Sbjct: 437 --DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLN 494
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+V + +TWY+ G L PSR I+ G L + VT D+G Y C SN G
Sbjct: 495 CLVASQAPHTITWYKRGGSL-PSRHQIV-----GS-RLRIPQVTPADSGEYVCHVSNGAG 547
Query: 3349 RASTSGKVEVIGTDQTSEPRI-PPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEV 3407
TS V + G+ + P + PP+ I S P + EG T+ + C V
Sbjct: 548 SRETSLIVTIQGSGSSHVPSVSPPIRIE-----SSSPTVV---------EGQTLDLNCVV 593
Query: 3408 VGDPKPDVYWLR 3419
P+ + W +
Sbjct: 594 ARQPQAIITWYK 605
Score = 58.8 bits (136), Expect = 3e-07
Identities = 75/327 (22%), Positives = 119/327 (36%), Gaps = 40/327 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET +L C V G+ V W K G G + S L + ++ D G
Sbjct: 678 VAEGETLDLNCVVPGQAHAQVTWHKRG-------GSLPSHHQTRGSRLRLHHVSPADSGE 730
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C + G + + +A G PP + RV
Sbjct: 731 YVCRVMGSSGPLEASVLVTI---------EASGSSAVHVPAPGGAPP-IRIEPSSSRVAE 780
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ +++P D G Y
Sbjct: 781 GQTLDLKCVVPGQAHAQVTWHKRGGNL---PARHQVHGPLLRLNQVSPA---DSGEYSCQ 834
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYV-APEFCCGLEPLY------KLHEGDELRISAVVEAY 3294
+SG + + ++ + AP +P+Y + EG L ++ VV
Sbjct: 835 VTGSSGTLEASVLVTIEPSSPGPIPAPGLA---QPIYIEASSSHVTEGQTLDLNCVVPGQ 891
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
VTWY+ G L P+R Q+ L L V+ D+G Y C A++ G +
Sbjct: 892 AHAQVTWYKRGGSL-PARHQT----HGSQLRLHL--VSPADSGEYVCRAASGPGPEQEAS 944
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ + S R+ VIS D P S
Sbjct: 945 FTVTVPPSEGSSYRLRSPVISIDPPSS 971
Score = 57.6 bits (133), Expect = 7e-07
Identities = 73/313 (23%), Positives = 114/313 (36%), Gaps = 50/313 (15%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF 3105
AG P V + P G + C+V + W K G G++ +
Sbjct: 1336 AGSTPT-VQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEG-------GQLPPGHSVQ 1387
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
D L I++++ +G Y C+A GKA A+L + +V
Sbjct: 1388 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL----------------- 1430
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
+R + V + V C +G P P+V+W K G + R Q +
Sbjct: 1431 ----INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL----RPGIVQSGG--VV 1480
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
IA L D G Y TA N +G H L+V P+ E ++ G
Sbjct: 1481 RIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ------ALPQISMPQE--VRVPAGSAA 1532
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
+ YP+ ++W + L P R + L L +V +DAG Y CTA+N
Sbjct: 1533 VFPCIASGYPTPDISWSKLDGSLPPDSRLENNM-------LMLPSVRPQDAGTYVCTATN 1585
Query: 3346 EVGRASTSGKVEV 3358
G+ ++V
Sbjct: 1586 RQGKVKAFAHLQV 1598
Score = 57.2 bits (132), Expect = 1e-06
Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 54/401 (13%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILP-GQLKILAGETANLTCSVKGKPV 3079
+R N YG +S V L+ P V +LP G + + G+ L C G+P
Sbjct: 1029 YRCVASNAYGVAQSV-------VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPR 1081
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
W + + + T L I D G Y C A N G A +
Sbjct: 1082 SSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 1140
Query: 3140 AVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKV 3199
V T A G PQ + V+A + L C GSP P +
Sbjct: 1141 IVDT---------------GAMAPG--APQVQAEEAELTVEAGHTATLRCSATGSPAPTI 1183
Query: 3200 SWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK 3259
W K + + R + TL I D G Y A + +G L V+
Sbjct: 1184 HWSKLRSPLPWQYRL------EGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVES 1237
Query: 3260 GIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLD 3319
A PE + G+ +++ + P + W R G L P R
Sbjct: 1238 PPYATTVPEHA-------SVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATA---- 1285
Query: 3320 RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVP 3379
R+ + AA D+G Y C +N+VG A ++ V G P + + +P
Sbjct: 1286 RNELLHFERAA--PEDSGRYRCRVTNKVGSAEAFAQLLVQGP--------PGSLPATSIP 1335
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P P+ G +V C V D + W ++
Sbjct: 1336 AGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKE 1376
Score = 56.8 bits (131), Expect = 1e-06
Identities = 84/356 (23%), Positives = 130/356 (36%), Gaps = 43/356 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G V W + G + +Q +G L + ++ D G
Sbjct: 2 VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPH-----TQVHGSR--LRLPQVSPADSGE 54
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C N G ++V+ V G P + V
Sbjct: 55 YVCRVENGSGPKEASITVSVL--------HGTHSGPSYTPVPGSTRP-IRIEPSSSHVAE 105
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
+ L C V G +V+W+K G + R++ ++ P D G Y
Sbjct: 106 GQTLDLNCVVPGQAHAQVTWHKRGGSL---PARHQTHGSLLRLHQVTPA---DSGEYVCH 159
Query: 3242 ARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
SG + + ++ + P + EG L +S VV VTW
Sbjct: 160 VVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSS-TVAEGQTLDLSCVVAGQAHAQVTW 218
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
Y+ G L P+R + R ++ + A+ DAG Y C ASN + + T V V GT
Sbjct: 219 YKRGGSL-PARHQV----RGSRLYIFQASPA--DAGQYVCRASNGMEASIT---VTVTGT 268
Query: 3362 DQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
Q + P S +P+ I +P SS+ EG T+ + C V G V W
Sbjct: 269 -QGANLAYPAG--------STQPIRI-EPSSSQVAEGQTLDLNCVVPGQSHAQVTW 314
Score = 56.4 bits (130), Expect = 2e-06
Identities = 87/368 (23%), Positives = 138/368 (37%), Gaps = 54/368 (14%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
+ I P + G+T +L C V G+ V W K G G + ++ L +
Sbjct: 94 IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRG-------GSLPARHQTHGSLLRLH 146
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ D G Y C T G A + V + +V + G PP +
Sbjct: 147 QVTPADSGEYVCHVVGTSGPLE--ASVLVTIEASV--------------IPGPIPP-VRI 189
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
V + L+C V G +V+WYK G + R++ + + + + +P
Sbjct: 190 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL---PARHQVRGSRLYIFQASPA-- 244
Query: 3233 DDGGVYEVTARNNSGAVSCHCGLVVDKGIR-AYVAPEFC-CGLEPLY-KLHEGDELRISA 3289
D G Y A N A S + +G AY A +EP ++ EG L ++
Sbjct: 245 -DAGQYVCRASNGMEA-SITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 302
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
VV VTW++ G L P R G + L L + D+G Y C V
Sbjct: 303 VVPGQSHAQVTWHKRGGSL-PVRH-----QTHGSL-LRLYQASPADSGEYVC----RVLG 351
Query: 3350 ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVG 3409
+S + V+ T + + +P + ++P V SS+ EG T+ + C V G
Sbjct: 352 SSVPLEASVLVTIEPAGS-VPALGVTPTVRIESS--------SSQVAEGQTLDLNCLVAG 402
Query: 3410 DPKPDVYW 3417
V W
Sbjct: 403 QAHAQVTW 410
Score = 56.4 bits (130), Expect = 2e-06
Identities = 72/319 (22%), Positives = 115/319 (36%), Gaps = 45/319 (14%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLIT 2650
R PV S T +G C + + P ++ W L++ + +IT
Sbjct: 960 RSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPN--GSIIT 1017
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVY--PSFEASPIPPTFTRSIRDTFHLAE 2708
++ PS+ Y C N G + NL V+ P+ P P + +
Sbjct: 1018 --IVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--------VG 1067
Query: 2709 NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ LEC G+P W + P+ + + L D L I + P D+GTY C
Sbjct: 1068 KAVTLECVSAGEPRSSARWTRISST-PAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 1126
Query: 2769 AENSVWTDQ-ITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
A+N++ T Q + TG + +P V E + V G
Sbjct: 1127 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE--------------------AELTVEAG 1166
Query: 2828 GTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCR 2886
T L+ G P + W + + YR +E TL + V + +SG Y C
Sbjct: 1167 HTATLRCSATGSPAPTIHWSKLRSPLPWQYR-----LEGD--TLIIPRVAQQDSGQYICN 1219
Query: 2887 AWSAHGNVDMNAAITVVQP 2905
A S G+ + + V P
Sbjct: 1220 ATSPAGHAEATIILHVESP 1238
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 21/184 (11%)
Query: 2594 PVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P ++T + + +V+ G V+L C + T W R G L + R +L L
Sbjct: 1238 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LH 1291
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAEN 2709
A P DS Y C V N+ G+ A L V S A+ IP T +++ T L
Sbjct: 1292 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 1351
Query: 2710 EL----VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ C + ++ WFK+ Q+P Q DGV R I N GTY
Sbjct: 1352 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQ-----DGVLR--IQNLDQSCQGTY 1404
Query: 2766 TCKA 2769
C+A
Sbjct: 1405 ICQA 1408
Score = 54.8 bits (126), Expect = 5e-06
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 21/169 (12%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
+T V G V+ C + P VTW + G L R +V + + + +D+
Sbjct: 1438 QTVVVGHAVEFECLALGDPKPQVTWSKVGGHL------RPGIVQSGGVVRIAHVELADAG 1491
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
+Y CT N G + L V +A P + + +R A + V C G P
Sbjct: 1492 QYRCTATNAAGTTQSHVLLLV----QALP-QISMPQEVRVP---AGSAAVFPCIASGYPT 1543
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
P I+W K D +P D R L + + L + + P+D+GTY C A N
Sbjct: 1544 PDISWSKLDGSLPPDSR-----LENNM--LMLPSVRPQDAGTYVCTATN 1585
Score = 53.6 bits (123), Expect = 1e-05
Identities = 85/358 (23%), Positives = 126/358 (35%), Gaps = 50/358 (13%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ G+T +L C V G+ V W K G G + ++ L + ++ D G
Sbjct: 876 VTEGQTLDLNCVVPGQAHAQVTWYKRG-------GSLPARHQTHGSQLRLHLVSPADSGE 928
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A + G A V TV ++ R RS + D PP T VQ
Sbjct: 929 YVCRAASGPGPEQE-ASFTV----TVPPSEGSSYRLRSPVISID-PPSST-------VQQ 975
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
C + G+ P + W +E+ N + + I T + G Y
Sbjct: 976 GQDASFKCLIHDGAAPISLEWKTRNQEL----EDNVHISPNGSIITIVGTRPSNHGTYRC 1031
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
A N G L V V PE P++ + G + + V P
Sbjct: 1032 VASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVW-VKVGKAVTLECVSAGEPRSSAR 1085
Query: 3301 WYRDGVRLRPSRRAIMTLD-RDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
W R + P++ T D L +++ DAG Y C A N +G A +VEVI
Sbjct: 1086 WTR--ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK--QVEVI 1141
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P P V ++E + EA G T + C G P P ++W
Sbjct: 1142 VDTGAMAPGAPQV-------QAEEAEL-----TVEA--GHTATLRCSATGSPAPTIHW 1185
Score = 53.2 bits (122), Expect = 2e-05
Identities = 74/359 (20%), Positives = 129/359 (35%), Gaps = 45/359 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T G L CS S PT+ W + L + L ++ +L TL + DS +
Sbjct: 1162 TVEAGHTATLRCSATGSPAPTIHWSK----LRSPLPWQYRLEGD--TLIIPRVAQQDSGQ 1215
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C + G + L V A+ +P + +T L +C G P
Sbjct: 1216 YICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQL-------QCLAHGTPPL 1268
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
W + +P GR A L + PEDSG Y C+ N V + + +
Sbjct: 1269 TFQWSRVGSSLP--GRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 1321
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
G + + A T + + + G ++ A G T++
Sbjct: 1322 VQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG-ASVEFHCAVPSDRG---------TQL 1371
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +EG + + V+ G+ L + ++ ++ G Y C+A G +A + +
Sbjct: 1372 RWFKEGGQLPPGHS-----VQDGV--LRIQNLDQSCQGTYICQAHGPWGKAQASAQLVI- 1423
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPG--EPCVVDGG 2960
P+V++ + VG + G+PKP+ ++ G P +V G
Sbjct: 1424 -----QALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG 1477
Score = 47.2 bits (107), Expect = 0.001
Identities = 75/360 (20%), Positives = 128/360 (35%), Gaps = 35/360 (9%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SS++ V G P + I P ++ G+T +L C V G+ V W K G G
Sbjct: 755 SSAVHVPAPGGAPP-IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRG-------GN 806
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE 3157
+ ++ L + ++ D G YSC+ T G + T +VT +
Sbjct: 807 LPARHQVHGPLLRLNQVSPADSGEYSCQVT---GSSGTLEASVLVT--------IEPSSP 855
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
G P + + V + L C V G +V+WYK G + R++
Sbjct: 856 GPIPAPGLAQPIY-IEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL---PARHQT 911
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSG---AVSCHCGLVVDKGIRAYVAPEFCCGLE 3274
Q ++P D G Y A + G S + +G +
Sbjct: 912 HGSQLRLHLVSPA---DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDP 968
Query: 3275 PLYKLHEGDELRISAVV-EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
P + +G + ++ + + + W L + + + +G I + +
Sbjct: 969 PSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VHISPNGSI-ITIVGTRP 1023
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
+ G Y C ASN G A + + V G S PV + + E + +PRSS
Sbjct: 1024 SNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSS 1083
Score = 44.4 bits (100), Expect = 0.007
Identities = 59/240 (24%), Positives = 90/240 (37%), Gaps = 36/240 (15%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L C V GS +V+WY+ G + + + +++P D G Y N S
Sbjct: 10 LNCVVAGSAHAQVTWYRRGGSL---PPHTQVHGSRLRLPQVSPA---DSGEYVCRVENGS 63
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCG------LEPLYK-LHEGDELRISAVVEAYPSVGV 3299
G + V G + + G +EP + EG L ++ VV V
Sbjct: 64 GPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQV 123
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
TW++ G L P+R G + L L VT D+G Y C V+
Sbjct: 124 TWHKRGGSL-PARH-----QTHGSL-LRLHQVTPADSGEYVC---------------HVV 161
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
GT E + + + +P P+ I + SS EG T+ + C V G V W +
Sbjct: 162 GTSGPLEASVLVTIEASVIPGPIPPVRI-ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYK 220
Score = 41.9 bits (94), Expect = 0.039
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 18/170 (10%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ V+ C+V S + W++ G +L + DG++ ++ L+ S Y C
Sbjct: 1354 GASVEFHCAVPSDRGTQLRWFKEG----GQLPPGHSVQDGVLRIQNLDQ--SCQGTYICQ 1407
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
G SA L + +A P R+ T + + + EC G P P++TW
Sbjct: 1408 AHGPWGKAQASAQLVI----QALPSVLINIRTSVQTV-VVGHAVEFECLALGDPKPQVTW 1462
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K + G Q+ GV R+A + D+G Y C A N+ T Q
Sbjct: 1463 SKVGGHL-RPGIVQS----GGVVRIA--HVELADAGQYRCTATNAAGTTQ 1505
Score = 39.9 bits (89), Expect = 0.16
Identities = 53/234 (22%), Positives = 78/234 (33%), Gaps = 40/234 (17%)
Query: 3031 WGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE 3090
WG++ ++ + L ++I ++ G C G P P V W K G
Sbjct: 1412 WGKAQASAQLVIQALPS---VLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH 1468
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
+ Q G + I + + D G+Y C ATN G ++ L V
Sbjct: 1469 LRPGI----VQSGGV---VRIAHVELADAGQYRCTATNAAGTTQSHVLLLV--------- 1512
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
PQ +M ++ RV A C G P P +SW K +
Sbjct: 1513 --------------QALPQISMP-QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPP 1557
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAY 3264
D R + L + D G Y TA N G V L V + + Y
Sbjct: 1558 DSRLEN------NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPY 1605
Score = 34.7 bits (76), Expect = 5.9
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 10/105 (9%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
GS C P ++W + LD L +L + ++ L + P D+ Y CT
Sbjct: 1529 GSAAVFPCIASGYPTPDISWSK----LDGSLPPDSRLENNMLMLPSVR--PQDAGTYVCT 1582
Query: 2668 VENENGAISTSANL----KVYPSFEASPIPPTFTRSIRDTFHLAE 2708
N G + A+L +V P F +P +I+D + E
Sbjct: 1583 ATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFE 1627
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 81.0 bits (191), Expect = 7e-14
Identities = 79/320 (24%), Positives = 133/320 (41%), Gaps = 48/320 (15%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQ 3101
G+ G+ +++ P ++ + L C G PVP + W + +G + + SQ
Sbjct: 220 GVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQ 279
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
L I + +DEG Y C A+N G+ +L
Sbjct: 280 -----AILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYA------------------ 316
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
PP++ ++++ + + C+ G P P +W K+GE + ++R Q E
Sbjct: 317 -----PPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEER---IQIEN 368
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK--- 3278
TL I N+ D GVY+ A N + + L V AP+F P+ K
Sbjct: 369 -GTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLAS-----APDF--SKSPVKKKSF 420
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ G ++ I A+P ++W R LR S+R + DG +++ +T DAG
Sbjct: 421 VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLL--EDGSLKIY--NITRSDAGS 476
Query: 3339 YTCTASNEVGRASTSGKVEV 3358
YTC A+N+ G A +G + V
Sbjct: 477 YTCIATNQFGTAKNTGSLIV 496
Score = 77.0 bits (181), Expect = 1e-12
Identities = 85/346 (24%), Positives = 145/346 (41%), Gaps = 56/346 (16%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A + S VKL C + + P ++W R +G L K+KY K LE+ N D
Sbjct: 239 AAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQA----ILEIPNFQQEDEGF 294
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G L Y PP + + I++T + L+ EC+ G+P P
Sbjct: 295 YECIASNLRGRNLAKGQLIFYA-------PPEWEQKIQNTHLSIYDNLLWECKASGKPNP 347
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
TW K+ +++ + R Q + +G + + N + DSG Y C AEN + +
Sbjct: 348 WYTWLKNGERLNPEERIQ---IENGTLIITMLNVS--DSGVYQCAAENK-------YQII 395
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TR 2842
+ E +V + K+ + ++S V GG I + + P
Sbjct: 396 YANAELRVLASAPDFSKSPVKKKSF---------------VQVGGDIVIGCKPNAFPRAA 440
Query: 2843 VEWLREGRSVTEVYRNA-RVF-VEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ W R TE R + R+F +E G +L + ++T +++G YTC A + G ++
Sbjct: 441 ISWKRG----TETLRQSKRIFLLEDG--SLKIYNITRSDAGSYTCIATNQFGTAKNTGSL 494
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
V K ++ P + ++VGE I + + +P + V
Sbjct: 495 IV--------KERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVV 532
Score = 64.9 bits (151), Expect = 5e-09
Identities = 88/332 (26%), Positives = 138/332 (41%), Gaps = 55/332 (16%)
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V+E+ R SQ G L I + D G Y+C TN + S + RT
Sbjct: 166 VQEDNRRFVSQETGN---LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRT---- 218
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP--VRLTCQVIGSPPPKVSWYK-DGEE 3207
D V G+Y P+ +R + +QA V+L C +G+P P +SW + DG
Sbjct: 219 DG---------VMGEYEPKIEVRFPET-IQAAKDSSVKLECFALGNPVPDISWRRLDGSP 268
Query: 3208 VVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP 3267
+ + KY Q LEI +D G YE A N G L+ Y P
Sbjct: 269 L---PGKVKYSKSQ-AILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIF------YAPP 318
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
E+ ++ + L D L P+ TW ++G RL P R + +G + +
Sbjct: 319 EWEQKIQNTH-LSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI---ENGTLIIT 374
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI 3387
+ V+ D+GVY C A N K ++I + +E R+ + +PD +SK P+
Sbjct: 375 MLNVS--DSGVYQCAAEN---------KYQIIYAN--AELRV--LASAPD--FSKSPV-- 415
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+ S + G ++I C+ P+ + W R
Sbjct: 416 --KKKSFVQVGGDIVIGCKPNAFPRAAISWKR 445
Score = 41.9 bits (94), Expect = 0.039
Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 7/86 (8%)
Query: 2694 PTFTRSIRDTFH---LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC 2750
P FT+ D L+++E++L C G P P W ++ I Y Y DG
Sbjct: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYH--YRLDG-G 82
Query: 2751 RLAIDNP-TPEDSGTYTCKAENSVWT 2775
LAI++P T +D G Y C A N + T
Sbjct: 83 SLAINSPHTDQDIGMYQCLATNLLGT 108
Score = 37.5 bits (83), Expect = 0.84
Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 11/160 (6%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW G E + + + S +N+ + + + N++G T+ + G +
Sbjct: 442 SWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFG------TAKNTGSLI 495
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGV--VWMKNGHEVEEEAGRMTSQFN 3103
+R + + P ++ + GE+ L C V P V VW NG ++ + G +
Sbjct: 496 VKERT-VITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERI 554
Query: 3104 GFDCC--LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
G + L I++I + G+Y C T S A + V
Sbjct: 555 GGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIV 594
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 81.0 bits (191), Expect = 7e-14
Identities = 79/320 (24%), Positives = 133/320 (41%), Gaps = 48/320 (15%)
Query: 3044 GLAGDRPEFVDI-LPGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTSQ 3101
G+ G+ +++ P ++ + L C G PVP + W + +G + + SQ
Sbjct: 220 GVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQ 279
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
L I + +DEG Y C A+N G+ +L
Sbjct: 280 -----AILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYA------------------ 316
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
PP++ ++++ + + C+ G P P +W K+GE + ++R Q E
Sbjct: 317 -----PPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEER---IQIEN 368
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK--- 3278
TL I N+ D GVY+ A N + + L V AP+F P+ K
Sbjct: 369 -GTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLAS-----APDF--SKSPVKKKSF 420
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ G ++ I A+P ++W R LR S+R + DG +++ +T DAG
Sbjct: 421 VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLL--EDGSLKIY--NITRSDAGS 476
Query: 3339 YTCTASNEVGRASTSGKVEV 3358
YTC A+N+ G A +G + V
Sbjct: 477 YTCIATNQFGTAKNTGSLIV 496
Score = 77.0 bits (181), Expect = 1e-12
Identities = 85/346 (24%), Positives = 145/346 (41%), Gaps = 56/346 (16%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A + S VKL C + + P ++W R +G L K+KY K LE+ N D
Sbjct: 239 AAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQA----ILEIPNFQQEDEGF 294
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C N G L Y PP + + I++T + L+ EC+ G+P P
Sbjct: 295 YECIASNLRGRNLAKGQLIFYA-------PPEWEQKIQNTHLSIYDNLLWECKASGKPNP 347
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
TW K+ +++ + R Q + +G + + N + DSG Y C AEN + +
Sbjct: 348 WYTWLKNGERLNPEERIQ---IENGTLIITMLNVS--DSGVYQCAAENK-------YQII 395
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TR 2842
+ E +V + K+ + ++S V GG I + + P
Sbjct: 396 YANAELRVLASAPDFSKSPVKKKSF---------------VQVGGDIVIGCKPNAFPRAA 440
Query: 2843 VEWLREGRSVTEVYRNA-RVF-VEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ W R TE R + R+F +E G +L + ++T +++G YTC A + G ++
Sbjct: 441 ISWKRG----TETLRQSKRIFLLEDG--SLKIYNITRSDAGSYTCIATNQFGTAKNTGSL 494
Query: 2901 TVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
V K ++ P + ++VGE I + + +P + V
Sbjct: 495 IV--------KERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVV 532
Score = 64.9 bits (151), Expect = 5e-09
Identities = 88/332 (26%), Positives = 138/332 (41%), Gaps = 55/332 (16%)
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V+E+ R SQ G L I + D G Y+C TN + S + RT
Sbjct: 166 VQEDNRRFVSQETGN---LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRT---- 218
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP--VRLTCQVIGSPPPKVSWYK-DGEE 3207
D V G+Y P+ +R + +QA V+L C +G+P P +SW + DG
Sbjct: 219 DG---------VMGEYEPKIEVRFPET-IQAAKDSSVKLECFALGNPVPDISWRRLDGSP 268
Query: 3208 VVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP 3267
+ + KY Q LEI +D G YE A N G L+ Y P
Sbjct: 269 L---PGKVKYSKSQ-AILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIF------YAPP 318
Query: 3268 EFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
E+ ++ + L D L P+ TW ++G RL P R + +G + +
Sbjct: 319 EWEQKIQNTH-LSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI---ENGTLIIT 374
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFI 3387
+ V+ D+GVY C A N K ++I + +E R+ + +PD +SK P+
Sbjct: 375 MLNVS--DSGVYQCAAEN---------KYQIIYAN--AELRV--LASAPD--FSKSPV-- 415
Query: 3388 RKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+ S + G ++I C+ P+ + W R
Sbjct: 416 --KKKSFVQVGGDIVIGCKPNAFPRAAISWKR 445
Score = 41.9 bits (94), Expect = 0.039
Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 7/86 (8%)
Query: 2694 PTFTRSIRDTFH---LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC 2750
P FT+ D L+++E++L C G P P W ++ I Y Y DG
Sbjct: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYH--YRLDG-G 82
Query: 2751 RLAIDNP-TPEDSGTYTCKAENSVWT 2775
LAI++P T +D G Y C A N + T
Sbjct: 83 SLAINSPHTDQDIGMYQCLATNLLGT 108
Score = 37.5 bits (83), Expect = 0.84
Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 11/160 (6%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW G E + + + S +N+ + + + N++G T+ + G +
Sbjct: 442 SWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFG------TAKNTGSLI 495
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGV--VWMKNGHEVEEEAGRMTSQFN 3103
+R + + P ++ + GE+ L C V P V VW NG ++ + G +
Sbjct: 496 VKERT-VITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERI 554
Query: 3104 GFDCC--LTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
G + L I++I + G+Y C T S A + V
Sbjct: 555 GGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIV 594
>AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member 3
protein.
Length = 1437
Score = 80.6 bits (190), Expect = 9e-14
Identities = 119/474 (25%), Positives = 185/474 (39%), Gaps = 52/474 (10%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL----KYRKKLVDG 2647
R P F L E + V LTC+V +S P VTWY+N +D +L KYR G
Sbjct: 152 RGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYG 211
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV---------YPS--FEASPIPPT- 2695
L++LE+ DSA Y+ V+N +G S+ A + V + S F+ S P+
Sbjct: 212 LLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSV 271
Query: 2696 -FTRSIRDTFHLAENELVLECRIRGQPL--PKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
FT ++ F + L C L I WF+D + S R + Y D L
Sbjct: 272 EFTSVLKPVFAREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILY-TDRQASL 330
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
+ ED G Y + + + + +V E++ +P A + + + L+ R
Sbjct: 331 KVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAE-NPG---APGSPLNVRCLDVNR 386
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
RG I R EW+ A G +
Sbjct: 387 DCLILTWAPPSDTRGNPITAYTIERCQGESGEWI------------ACHEAPGGTCRCPI 434
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
+ E +S + RA S G+ + A +V D D R + +I +G I
Sbjct: 435 QGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHD------AARRKTEIPFDLGNKIT 488
Query: 2933 ISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAE 2992
IS T +P P + +V LAW + P+ AP L Y +E +IG+
Sbjct: 489 IS--TDAFEDTVTIPSP-PTNVHASEIREAYVVLAWEEPSPRDRAP-LTYSLEKSVIGS- 543
Query: 2993 GGARWVELGI-TPLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGV 3043
W + +P+ S F +L++ + Y FRV N+YG + S+ S I +
Sbjct: 544 --GTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIAL 595
Score = 64.1 bits (149), Expect = 8e-09
Identities = 48/179 (26%), Positives = 78/179 (43%), Gaps = 8/179 (4%)
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEE---AGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
T LTC+V+ P P V W KN ++ AG+ N L I+ I+D Y+
Sbjct: 170 TVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYT 229
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
N HG+AS++A++ V RT DA E +FT L+ +
Sbjct: 230 VRVKNAHGQASSFAKVLV---RTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKE 286
Query: 3184 PVRLTCQVIGS--PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
P L+C + W++DG + +RR ++ +L+++ T +D G+Y V
Sbjct: 287 PFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMV 345
Score = 62.9 bits (146), Expect = 2e-08
Identities = 61/211 (28%), Positives = 89/211 (42%), Gaps = 22/211 (10%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQFH--- 3223
P F + LR V V LTC V SPPP+V+WYK+ + R KY+ +
Sbjct: 154 PWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLL 213
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV------DKGI------RAYVAP--EF 3269
+LEI ++D Y V +N G S ++V D G R+ P EF
Sbjct: 214 SLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSVEF 273
Query: 3270 CCGLEPLYKLHEGDELRISAVV--EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
L+P++ E + +S + + + + W+RDG LR SRR L D Q L
Sbjct: 274 TSVLKPVF-AREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRR-KILYTDRQASLK 331
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
++ D G+Y + G S V V
Sbjct: 332 VSCTYKEDEGLYMVRVPSPFGPREQSTYVLV 362
Score = 54.0 bits (124), Expect = 9e-06
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+R + V LP I+ +T LTC V G P P + W+KN V R + G +
Sbjct: 1332 NRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPV-TFLDRYRMEVRGTEV 1390
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+TI+ +N +D GRY N +G + ++V
Sbjct: 1391 TITIEKVNSEDSGRYGVFVKNKYGSETGQVTISV 1424
Score = 44.8 bits (101), Expect = 0.006
Identities = 75/321 (23%), Positives = 126/321 (39%), Gaps = 27/321 (8%)
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTD---RTVWEADAKLKRERSAEVEGDYP 3167
I++++ +D+G Y+ + + GKA L +V D + + +ADAK R +G Y
Sbjct: 1067 IQNLSEEDKGSYTAQLQD--GKAKNQITLTLVDDDFDKLLRKADAK--RRDWKRKQGPY- 1121
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPP-KVSWYKDGEEVVYDKRRNKYQDEQ-FHTL 3225
F L+ +V V+LTC+V + + W+ E+ +Y E L
Sbjct: 1122 --FERPLQ-WKVTEDCQVQLTCKVTNTKKETRFQWFFQRAEMP----DGQYDPETGTGLL 1174
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDK--GIRAYVAPEFCCGLEPLYKLHEGD 3283
I + D G+Y ++ G L D I + PL +
Sbjct: 1175 CIEELSKKDKGIYRAMVSDDRGEDDTILDLTGDALDAIFTELGRIGALSATPLKIQGTEE 1234
Query: 3284 ELRISAVVEAY--PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+RI + V+ Y + TW+ RL R I T +I L + D G YT
Sbjct: 1235 GIRIFSKVKYYNVEYMKTTWFHKDKRLESGDR-IRTGTTLDEIWLHILDPKDSDKGKYTL 1293
Query: 3342 --TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
A EV + ST + R+ + I + ++ + P + E
Sbjct: 1294 EIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAI---IEKNRAKVVRGLPDVATIMEDK 1350
Query: 3400 TVIIECEVVGDPKPDVYWLRD 3420
T+ + C V GDP P++ WL++
Sbjct: 1351 TLCLTCIVSGDPTPEISWLKN 1371
Score = 43.2 bits (97), Expect = 0.017
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVY-DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
LTC V G P P++SW K+ + V + D+ R + + + T+ I N +D G Y V +N
Sbjct: 1354 LTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEV-TITIEKVNSEDSGRYGVFVKNK 1412
Query: 3246 SGA 3248
G+
Sbjct: 1413 YGS 1415
Score = 40.7 bits (91), Expect = 0.090
Identities = 44/186 (23%), Positives = 72/186 (38%), Gaps = 9/186 (4%)
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
K TWF DK++ S R + D + L I +P D G YT + Q++
Sbjct: 1251 KTTWFHKDKRLESGDRIRTGTTLDEIW-LHILDPKDSDKGKYTLEIAAGKEVRQLS---- 1305
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDY-QVARGGTIGLQVEIRGCPT- 2841
T Q + + + +E R L D + T+ L + G PT
Sbjct: 1306 -TDLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTP 1364
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
+ WL+ + VT + R R+ V T+ + V +SG Y + +G+ I+
Sbjct: 1365 EISWLKNDQPVTFLDR-YRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTIS 1423
Query: 2902 VVQPSD 2907
V + D
Sbjct: 1424 VFKHGD 1429
Score = 40.3 bits (90), Expect = 0.12
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 2698 RSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
R + D + E++ L L C + G P P+I+W K+D+ + RY+ V + I+
Sbjct: 1338 RGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEV-TITIEK 1396
Query: 2757 PTPEDSGTYTCKAENSVW--TDQIT 2779
EDSG Y +N T Q+T
Sbjct: 1397 VNSEDSGRYGVFVKNKYGSETGQVT 1421
Score = 38.7 bits (86), Expect = 0.36
Identities = 26/115 (22%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Query: 2571 KAFSEARSVISEKRTLSRNSTRKPVFSTFLTD-RTAVEGSRVKLTCSVISSSDPTVTWYR 2629
+AF +A + +TL+ + L D T +E + LTC V P ++W +
Sbjct: 1311 QAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLK 1370
Query: 2630 NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
N + +YR ++ +T+ + DS Y V+N+ G+ + + V+
Sbjct: 1371 NDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTISVF 1425
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down syndrome
cell adhesion molecule protein.
Length = 812
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/348 (23%), Positives = 140/348 (40%), Gaps = 43/348 (12%)
Query: 3019 YHFRVTPRNRYGWGESSQTSSS--IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKG 3076
Y++R R+RY GE+ Q++S+ A P +D + K +AG+ L C G
Sbjct: 23 YNYRCITRHRYT-GETRQSNSARLFVSDPANSAPSILDGFDHR-KAMAGQRVELPCKALG 80
Query: 3077 KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
P P W+K+ +E +GR G L I++I D G Y CE +N +G A
Sbjct: 81 HPEPDYRWLKDNMPLEL-SGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVI 135
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPP 3196
RL V P + T+ R + V L+C V G+
Sbjct: 136 GRLYV-----------------------KQPLKATISPRKVKSSVGSQVSLSCSVTGTED 172
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++SWY++G E++ + + L + DGG Y+ R + + + +V
Sbjct: 173 QELSWYRNG-EILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVV 231
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG--VRLRPSRRA 3314
++ G P+ + + + + V+ P +TW D + S R
Sbjct: 232 LEDG-----TPKIISAFSEKV-VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 285
Query: 3315 IMTLDRDGQI--ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ +G + L +++ RD GVY CTA+N G ++ V G
Sbjct: 286 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG 333
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/191 (29%), Positives = 81/191 (42%), Gaps = 20/191 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F R ++ G RV + C V+S P T+TW ++G + L +D +L
Sbjct: 427 PFIQPFEFPRFSI-GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLR 485
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N + Y+C NE A+ + L V +PP F RD + ++
Sbjct: 486 ISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR-------VPPKFVVQPRDQDGIYGKAVI 538
Query: 2713 LECRIRGQPLPKITW-FKDDKQIPS------DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L C G P+P I W F +P +GR Q L++G L I + EDSG Y
Sbjct: 539 LNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQV--LSNG--SLLIKHVVEEDSGYY 594
Query: 2766 TCKAENSVWTD 2776
CK N V D
Sbjct: 595 LCKVSNDVGAD 605
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK 2642
+ + R ++P+ +T + GS+V L+CSV + D ++WYRNG +L+ R
Sbjct: 133 KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 192
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
++ L + + V SD Y C V + +S ++V I F+ +
Sbjct: 193 TGINH-ENLIMDHMVKSDGGAYQCFVRKDK--LSAQDYVQVVLEDGTPKIISAFSEKVVS 249
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPT 2758
AE + L C ++G PLP ITW DD I G R ++G V L I +
Sbjct: 250 P---AE-PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 305
Query: 2759 PEDSGTYTCKAENS 2772
D G Y C A NS
Sbjct: 306 VRDGGVYRCTANNS 319
Score = 62.5 bits (145), Expect = 3e-08
Identities = 84/378 (22%), Positives = 147/378 (38%), Gaps = 51/378 (13%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
R + E R S + +S + P R A+ G RV+L C + +P W
Sbjct: 30 RHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWL 89
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
++ + L+ ++ +K V GL+ + N PSDS Y C V N G L V +
Sbjct: 90 KDNMPLELSGRF-QKTVTGLL---IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 145
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ P R ++ + +++ L C + G +++W+++ +I + G+
Sbjct: 146 ATISP----RKVKSS---VGSQVSLSCSVTGTEDQELSWYRNG-EILNPGK-NVRITGIN 196
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
L +D+ D G Y C FV +Q VV L
Sbjct: 197 HENLIMDHMVKSDGGAYQC-------------FVRKDKLSAQDYVQVV-----------L 232
Query: 2809 ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTE--VYRNARVFVEQ 2865
E P + ++ V+ + L ++G P + W + + + +R +++ +
Sbjct: 233 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 292
Query: 2866 G--LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G + L +S + G+Y C A ++ G V A I V P+ + RP K+I
Sbjct: 293 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI---------RPMKNI 343
Query: 2924 LISVGEDINISFRTQGEP 2941
G D I R G P
Sbjct: 344 TAIAGRDTYIHCRVIGYP 361
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/352 (23%), Positives = 136/352 (38%), Gaps = 47/352 (13%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
N++ + + NRYG T+ IG L +P I P ++K G +L+
Sbjct: 112 NIRPSDSGSYVCEVSNRYG------TAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLS 164
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
CSV G + W +NG + + N + L + + D G Y C
Sbjct: 165 CSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQCFVRKDKL 222
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
A Y ++ V+ D T P+ ++ V PV L C V
Sbjct: 223 SAQDYVQV-VLEDGT---------------------PKIISAFSEKVVSPAEPVSLMCNV 260
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQ-----DEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
G+P P ++W D + ++ Q L I+ + + DGGVY TA N++
Sbjct: 261 KGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSA 320
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G V + V +G A + P ++ + + G + I V YP + WY++
Sbjct: 321 GVVLYQARINV-RG-PASIRP-----MKNITAI-AGRDTYIHCRVIGYPYYSIKWYKNS- 371
Query: 3307 RLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L P + + +G ++L+ D G YTC + + STS V V
Sbjct: 372 NLLPFNHRQVAFENNGTLKLSDVQKEV-DEGEYTCNVLVQ-PQLSTSQSVHV 421
Score = 54.8 bits (126), Expect = 5e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 24/196 (12%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE-- 2652
+ S F +++ V L C+V + PT+TW + D LK + +IT E
Sbjct: 239 IISAF-SEKVVSPAEPVSLMCNVKGTPLPTITWTLDD---DPILKGGSHRISQMITSEGN 294
Query: 2653 ---VLNAVPS---DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
LN S D Y CT N G + A + V P R +++ +
Sbjct: 295 VVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG--------PASIRPMKNITAI 346
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + + CR+ G P I W+K+ +P + R AF +G +L+ D D G YT
Sbjct: 347 AGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLS-DVQKEVDEGEYT 404
Query: 2767 CK--AENSVWTDQITH 2780
C + + T Q H
Sbjct: 405 CNVLVQPQLSTSQSVH 420
Score = 50.0 bits (114), Expect = 1e-04
Identities = 72/308 (23%), Positives = 122/308 (39%), Gaps = 52/308 (16%)
Query: 2664 YSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH----LAENELVLECRIR 2718
Y C + G S + +++ S A+ P SI D F +A + L C+
Sbjct: 25 YRCITRHRYTGETRQSNSARLFVSDPANSAP-----SILDGFDHRKAMAGQRVELPCKAL 79
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
G P P W KD+ + GR+Q V L I+N P DSG+Y C+ N T ++
Sbjct: 80 GHPEPDYRWLKDNMPLELSGRFQKT-----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 134
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
GR P K I+ + ++S + G + L + G
Sbjct: 135 ------IGRLYVKQP-----LKATISPRKVKS--------------SVGSQVSLSCSVTG 169
Query: 2839 CPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
+ + W R G + +N R+ L + + +++ G Y C D
Sbjct: 170 TEDQELSWYRNG-EILNPGKNVRI-TGINHENLIMDHMVKSDGGAYQCFV-----RKDKL 222
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+A VQ DG P +I EK ++S E +++ +G P P + + +P ++
Sbjct: 223 SAQDYVQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPLP-TITWTLDDDP-IL 278
Query: 2958 DGGNNWVS 2965
GG++ +S
Sbjct: 279 KGGSHRIS 286
Score = 49.2 bits (112), Expect = 3e-04
Identities = 50/207 (24%), Positives = 75/207 (36%), Gaps = 17/207 (8%)
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R+ A V L C+ +G P P W KD + R K L I D G
Sbjct: 64 RKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQK----TVTGLLIENIRPSDSG 119
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y N G L V + ++A ++P K G ++ +S V
Sbjct: 120 SYVCEVSNRYGTAKVIGRLYVKQPLKATISPR-------KVKSSVGSQVSLSCSVTGTED 172
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
++WYR+G L P + +T L + + D G Y C + + S V
Sbjct: 173 QELSWYRNGEILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKD--KLSAQDYV 228
Query: 3357 EVIGTDQTSE--PRIPPVVISPDVPYS 3381
+V+ D T + V+SP P S
Sbjct: 229 QVVLEDGTPKIISAFSEKVVSPAEPVS 255
Score = 48.8 bits (111), Expect = 3e-04
Identities = 68/292 (23%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
+AG + C V G P + W KN + + ++ + NG L + D+ + DEG
Sbjct: 346 IAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNG---TLKLSDVQKEVDEGE 402
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C +L +S V PP F R
Sbjct: 403 YTCNVL----------------------VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSI 439
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
V + C V+ G P ++W KDG + + +L I+ +L G Y
Sbjct: 440 GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC 499
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
ARN + AV L+V + V P G+ G + ++ E YP +
Sbjct: 500 IARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY-------GKAVILNCSAEGYPVPTIV 552
Query: 3301 W-YRDGVRLRPSRRAIMTLDRDGQIE---LALAAVTTRDAGVYTCTASNEVG 3348
W + G + P + I R + L + V D+G Y C SN+VG
Sbjct: 553 WKFSKGAGV-PQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 603
Score = 48.0 bits (109), Expect = 6e-04
Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 12/187 (6%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
+R + R P + + TA+ G + C VI ++ WY+N LL +R+ +
Sbjct: 327 ARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFE 384
Query: 2647 GLITLEVLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
TL++ + D EY+C V + +STS ++ V +PP F
Sbjct: 385 NNGTLKLSDVQKEVDEGEYTCNVLVQ-PQLSTSQSVHV-----TVKVPPFIQPFEFPRFS 438
Query: 2706 LAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ + + + C + LP ITW KD + IP + D L I N + +G
Sbjct: 439 IGQ-RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI-DFTSSLRISNLSLMHNGN 496
Query: 2765 YTCKAEN 2771
YTC A N
Sbjct: 497 YTCIARN 503
Score = 46.8 bits (106), Expect = 0.001
Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 22/196 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLI--- 2649
P F D+ + G V L CS PT+ W + G + +++ ++G I
Sbjct: 520 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVP---QFQPIALNGRIQVL 576
Query: 2650 ---TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
+L + + V DS Y C V N+ GA +S S L V IP T T
Sbjct: 577 SNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV-------KIPAMITSYPNTTLA 629
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADG---VCRLAIDNPTPED 2761
+ + C G+ + W K+D+ I P RY G + L I ED
Sbjct: 630 TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVRED 689
Query: 2762 SGTYTCKAENSVWTDQ 2777
SG ++C A NS D+
Sbjct: 690 SGFFSCHAINSYGEDR 705
Score = 37.9 bits (84), Expect = 0.64
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEA-----GRMTSQFN 3103
P+FV + P + G+ L CS +G PVP +VW G V + GR+ N
Sbjct: 520 PKFV-VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 578
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHG 3131
G L IK + +D G Y C+ +N G
Sbjct: 579 G---SLLIKHVVEEDSGYYLCKVSNDVG 603
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 2012
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/348 (23%), Positives = 140/348 (40%), Gaps = 43/348 (12%)
Query: 3019 YHFRVTPRNRYGWGESSQTSSS--IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKG 3076
Y++R R+RY GE+ Q++S+ A P +D + K +AG+ L C G
Sbjct: 193 YNYRCITRHRYT-GETRQSNSARLFVSDPANSAPSILDGFDHR-KAMAGQRVELPCKALG 250
Query: 3077 KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
P P W+K+ +E +GR G L I++I D G Y CE +N +G A
Sbjct: 251 HPEPDYRWLKDNMPLEL-SGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVI 305
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPP 3196
RL V P + T+ R + V L+C V G+
Sbjct: 306 GRLYV-----------------------KQPLKATISPRKVKSSVGSQVSLSCSVTGTED 342
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++SWY++G E++ + + L + DGG Y+ R + + + +V
Sbjct: 343 QELSWYRNG-EILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVV 401
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG--VRLRPSRRA 3314
++ G P+ + + + + V+ P +TW D + S R
Sbjct: 402 LEDG-----TPKIISAFSEKV-VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 455
Query: 3315 IMTLDRDGQI--ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ +G + L +++ RD GVY CTA+N G ++ V G
Sbjct: 456 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG 503
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/191 (29%), Positives = 81/191 (42%), Gaps = 20/191 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F R ++ G RV + C V+S P T+TW ++G + L +D +L
Sbjct: 597 PFIQPFEFPRFSI-GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLR 655
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N + Y+C NE A+ + L V +PP F RD + ++
Sbjct: 656 ISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR-------VPPKFVVQPRDQDGIYGKAVI 708
Query: 2713 LECRIRGQPLPKITW-FKDDKQIPS------DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L C G P+P I W F +P +GR Q L++G L I + EDSG Y
Sbjct: 709 LNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQV--LSNG--SLLIKHVVEEDSGYY 764
Query: 2766 TCKAENSVWTD 2776
CK N V D
Sbjct: 765 LCKVSNDVGAD 775
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK 2642
+ + R ++P+ +T + GS+V L+CSV + D ++WYRNG +L+ R
Sbjct: 303 KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 362
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
++ L + + V SD Y C V + +S ++V I F+ +
Sbjct: 363 TGINH-ENLIMDHMVKSDGGAYQCFVRKDK--LSAQDYVQVVLEDGTPKIISAFSEKVVS 419
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPT 2758
AE + L C ++G PLP ITW DD I G R ++G V L I +
Sbjct: 420 P---AE-PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 475
Query: 2759 PEDSGTYTCKAENS 2772
D G Y C A NS
Sbjct: 476 VRDGGVYRCTANNS 489
Score = 62.5 bits (145), Expect = 3e-08
Identities = 84/378 (22%), Positives = 147/378 (38%), Gaps = 51/378 (13%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
R + E R S + +S + P R A+ G RV+L C + +P W
Sbjct: 200 RHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWL 259
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
++ + L+ ++ +K V GL+ + N PSDS Y C V N G L V +
Sbjct: 260 KDNMPLELSGRF-QKTVTGLL---IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 315
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ P R ++ + +++ L C + G +++W+++ +I + G+
Sbjct: 316 ATISP----RKVKSS---VGSQVSLSCSVTGTEDQELSWYRNG-EILNPGK-NVRITGIN 366
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
L +D+ D G Y C FV +Q VV L
Sbjct: 367 HENLIMDHMVKSDGGAYQC-------------FVRKDKLSAQDYVQVV-----------L 402
Query: 2809 ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTE--VYRNARVFVEQ 2865
E P + ++ V+ + L ++G P + W + + + +R +++ +
Sbjct: 403 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 462
Query: 2866 G--LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G + L +S + G+Y C A ++ G V A I V P+ + RP K+I
Sbjct: 463 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI---------RPMKNI 513
Query: 2924 LISVGEDINISFRTQGEP 2941
G D I R G P
Sbjct: 514 TAIAGRDTYIHCRVIGYP 531
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/352 (23%), Positives = 136/352 (38%), Gaps = 47/352 (13%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
N++ + + NRYG T+ IG L +P I P ++K G +L+
Sbjct: 282 NIRPSDSGSYVCEVSNRYG------TAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLS 334
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
CSV G + W +NG + + N + L + + D G Y C
Sbjct: 335 CSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQCFVRKDKL 392
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
A Y ++ V+ D T P+ ++ V PV L C V
Sbjct: 393 SAQDYVQV-VLEDGT---------------------PKIISAFSEKVVSPAEPVSLMCNV 430
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQ-----DEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
G+P P ++W D + ++ Q L I+ + + DGGVY TA N++
Sbjct: 431 KGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSA 490
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G V + V +G A + P ++ + + G + I V YP + WY++
Sbjct: 491 GVVLYQARINV-RG-PASIRP-----MKNITAI-AGRDTYIHCRVIGYPYYSIKWYKNS- 541
Query: 3307 RLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L P + + +G ++L+ D G YTC + + STS V V
Sbjct: 542 NLLPFNHRQVAFENNGTLKLSDVQKEV-DEGEYTCNVLVQ-PQLSTSQSVHV 591
Score = 55.2 bits (127), Expect = 4e-06
Identities = 86/383 (22%), Positives = 152/383 (39%), Gaps = 58/383 (15%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT---WYRNGVLLDNKLKYRKKLVDGL 2648
R+P ++ + D+ + G+ C + SS + +T W ++ V L + ++ L
Sbjct: 123 REP-YTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGAL 181
Query: 2649 ITLEVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-- 2705
+V N Y C + G S + +++ S A+ P SI D F
Sbjct: 182 YIKDVQNE--DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAP-----SILDGFDHR 234
Query: 2706 --LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+A + L C+ G P P W KD+ + GR+Q V L I+N P DSG
Sbjct: 235 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKT-----VTGLLIENIRPSDSG 289
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
+Y C+ N T ++ GR P K I+ + ++S
Sbjct: 290 SYVCEVSNRYGTAKV------IGRLYVKQP-----LKATISPRKVKS------------- 325
Query: 2824 VARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
+ G + L + G + + W R G + +N R+ L + + +++ G
Sbjct: 326 -SVGSQVSLSCSVTGTEDQELSWYRNG-EILNPGKNVRI-TGINHENLIMDHMVKSDGGA 382
Query: 2883 YTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
Y C D +A VQ DG P +I EK ++S E +++ +G P
Sbjct: 383 YQCFV-----RKDKLSAQDYVQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPL 435
Query: 2943 PKAVPERIPGEPCVVDGGNNWVS 2965
P + + +P ++ GG++ +S
Sbjct: 436 P-TITWTLDDDP-ILKGGSHRIS 456
Score = 54.8 bits (126), Expect = 5e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 24/196 (12%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE-- 2652
+ S F +++ V L C+V + PT+TW + D LK + +IT E
Sbjct: 409 IISAF-SEKVVSPAEPVSLMCNVKGTPLPTITWTLDD---DPILKGGSHRISQMITSEGN 464
Query: 2653 ---VLNAVPS---DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
LN S D Y CT N G + A + V P R +++ +
Sbjct: 465 VVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG--------PASIRPMKNITAI 516
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + + CR+ G P I W+K+ +P + R AF +G +L+ D D G YT
Sbjct: 517 AGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLS-DVQKEVDEGEYT 574
Query: 2767 CK--AENSVWTDQITH 2780
C + + T Q H
Sbjct: 575 CNVLVQPQLSTSQSVH 590
Score = 49.2 bits (112), Expect = 3e-04
Identities = 50/207 (24%), Positives = 75/207 (36%), Gaps = 17/207 (8%)
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R+ A V L C+ +G P P W KD + R K L I D G
Sbjct: 234 RKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQK----TVTGLLIENIRPSDSG 289
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y N G L V + ++A ++P K G ++ +S V
Sbjct: 290 SYVCEVSNRYGTAKVIGRLYVKQPLKATISPR-------KVKSSVGSQVSLSCSVTGTED 342
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
++WYR+G L P + +T L + + D G Y C + + S V
Sbjct: 343 QELSWYRNGEILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKD--KLSAQDYV 398
Query: 3357 EVIGTDQTSE--PRIPPVVISPDVPYS 3381
+V+ D T + V+SP P S
Sbjct: 399 QVVLEDGTPKIISAFSEKVVSPAEPVS 425
Score = 48.8 bits (111), Expect = 3e-04
Identities = 68/292 (23%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
+AG + C V G P + W KN + + ++ + NG L + D+ + DEG
Sbjct: 516 IAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNG---TLKLSDVQKEVDEGE 572
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C +L +S V PP F R
Sbjct: 573 YTCNVL----------------------VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSI 609
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
V + C V+ G P ++W KDG + + +L I+ +L G Y
Sbjct: 610 GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC 669
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
ARN + AV L+V + V P G+ G + ++ E YP +
Sbjct: 670 IARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY-------GKAVILNCSAEGYPVPTIV 722
Query: 3301 W-YRDGVRLRPSRRAIMTLDRDGQIE---LALAAVTTRDAGVYTCTASNEVG 3348
W + G + P + I R + L + V D+G Y C SN+VG
Sbjct: 723 WKFSKGAGV-PQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 773
Score = 48.0 bits (109), Expect = 6e-04
Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 12/187 (6%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
+R + R P + + TA+ G + C VI ++ WY+N LL +R+ +
Sbjct: 497 ARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFE 554
Query: 2647 GLITLEVLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
TL++ + D EY+C V + +STS ++ V +PP F
Sbjct: 555 NNGTLKLSDVQKEVDEGEYTCNVLVQ-PQLSTSQSVHV-----TVKVPPFIQPFEFPRFS 608
Query: 2706 LAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ + + + C + LP ITW KD + IP + D L I N + +G
Sbjct: 609 IGQ-RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI-DFTSSLRISNLSLMHNGN 666
Query: 2765 YTCKAEN 2771
YTC A N
Sbjct: 667 YTCIARN 673
Score = 46.8 bits (106), Expect = 0.001
Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 22/196 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLI--- 2649
P F D+ + G V L CS PT+ W + G + +++ ++G I
Sbjct: 690 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVP---QFQPIALNGRIQVL 746
Query: 2650 ---TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
+L + + V DS Y C V N+ GA +S S L V IP T T
Sbjct: 747 SNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV-------KIPAMITSYPNTTLA 799
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADG---VCRLAIDNPTPED 2761
+ + C G+ + W K+D+ I P RY G + L I ED
Sbjct: 800 TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVRED 859
Query: 2762 SGTYTCKAENSVWTDQ 2777
SG ++C A NS D+
Sbjct: 860 SGFFSCHAINSYGEDR 875
Score = 44.8 bits (101), Expect = 0.006
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 8/73 (10%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPS----DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
++VL C+ G P P + W KD PS DGR F + R EDSG Y
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV----KAEDSGYY 1357
Query: 2766 TCKAENSVWTDQI 2778
+C A N+ +D+I
Sbjct: 1358 SCIANNNWGSDEI 1370
Score = 38.7 bits (86), Expect = 0.36
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL + +Y V G G SS+ I V P + G + + L
Sbjct: 1250 NLSRNRQYSVWVVAVTSAGRGNSSEI---ITVEPLAKAPARILTFSGTVTTPWMKDIVLP 1306
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEA---GRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
C G P P V WMK+ + GR + NG I+ + +D G YSC A N
Sbjct: 1307 CKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG---SFIIRTVKAEDSGYYSCIANN 1363
Query: 3129 THGKASTYARLAV 3141
G L V
Sbjct: 1364 NWGSDEIILNLQV 1376
Score = 37.9 bits (84), Expect = 0.64
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEA-----GRMTSQFN 3103
P+FV + P + G+ L CS +G PVP +VW G V + GR+ N
Sbjct: 690 PKFV-VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 748
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHG 3131
G L IK + +D G Y C+ +N G
Sbjct: 749 G---SLLIKHVVEEDSGYYLCKVSNDVG 773
Score = 37.9 bits (84), Expect = 0.64
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEE----VVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L C+ +G P P V W KD V D RR+ + + F I +D G Y A
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF---IIRTVKAEDSGYYSCIA 1361
Query: 3243 RNNSGA 3248
NN G+
Sbjct: 1362 NNNWGS 1367
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1571
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/348 (23%), Positives = 140/348 (40%), Gaps = 43/348 (12%)
Query: 3019 YHFRVTPRNRYGWGESSQTSSS--IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKG 3076
Y++R R+RY GE+ Q++S+ A P +D + K +AG+ L C G
Sbjct: 193 YNYRCITRHRYT-GETRQSNSARLFVSDPANSAPSILDGFDHR-KAMAGQRVELPCKALG 250
Query: 3077 KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
P P W+K+ +E +GR G L I++I D G Y CE +N +G A
Sbjct: 251 HPEPDYRWLKDNMPLEL-SGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVI 305
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPP 3196
RL V P + T+ R + V L+C V G+
Sbjct: 306 GRLYV-----------------------KQPLKATISPRKVKSSVGSQVSLSCSVTGTED 342
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++SWY++G E++ + + L + DGG Y+ R + + + +V
Sbjct: 343 QELSWYRNG-EILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVV 401
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG--VRLRPSRRA 3314
++ G P+ + + + + V+ P +TW D + S R
Sbjct: 402 LEDG-----TPKIISAFSEKV-VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 455
Query: 3315 IMTLDRDGQI--ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ +G + L +++ RD GVY CTA+N G ++ V G
Sbjct: 456 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG 503
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/191 (29%), Positives = 81/191 (42%), Gaps = 20/191 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F R ++ G RV + C V+S P T+TW ++G + L +D +L
Sbjct: 597 PFIQPFEFPRFSI-GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLR 655
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N + Y+C NE A+ + L V +PP F RD + ++
Sbjct: 656 ISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR-------VPPKFVVQPRDQDGIYGKAVI 708
Query: 2713 LECRIRGQPLPKITW-FKDDKQIPS------DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L C G P+P I W F +P +GR Q L++G L I + EDSG Y
Sbjct: 709 LNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQV--LSNG--SLLIKHVVEEDSGYY 764
Query: 2766 TCKAENSVWTD 2776
CK N V D
Sbjct: 765 LCKVSNDVGAD 775
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK 2642
+ + R ++P+ +T + GS+V L+CSV + D ++WYRNG +L+ R
Sbjct: 303 KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 362
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
++ L + + V SD Y C V + +S ++V I F+ +
Sbjct: 363 TGINH-ENLIMDHMVKSDGGAYQCFVRKDK--LSAQDYVQVVLEDGTPKIISAFSEKVVS 419
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPT 2758
AE + L C ++G PLP ITW DD I G R ++G V L I +
Sbjct: 420 P---AE-PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 475
Query: 2759 PEDSGTYTCKAENS 2772
D G Y C A NS
Sbjct: 476 VRDGGVYRCTANNS 489
Score = 62.5 bits (145), Expect = 3e-08
Identities = 84/378 (22%), Positives = 147/378 (38%), Gaps = 51/378 (13%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
R + E R S + +S + P R A+ G RV+L C + +P W
Sbjct: 200 RHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWL 259
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
++ + L+ ++ +K V GL+ + N PSDS Y C V N G L V +
Sbjct: 260 KDNMPLELSGRF-QKTVTGLL---IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 315
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ P R ++ + +++ L C + G +++W+++ +I + G+
Sbjct: 316 ATISP----RKVKSS---VGSQVSLSCSVTGTEDQELSWYRNG-EILNPGK-NVRITGIN 366
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
L +D+ D G Y C FV +Q VV L
Sbjct: 367 HENLIMDHMVKSDGGAYQC-------------FVRKDKLSAQDYVQVV-----------L 402
Query: 2809 ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTE--VYRNARVFVEQ 2865
E P + ++ V+ + L ++G P + W + + + +R +++ +
Sbjct: 403 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 462
Query: 2866 G--LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G + L +S + G+Y C A ++ G V A I V P+ + RP K+I
Sbjct: 463 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI---------RPMKNI 513
Query: 2924 LISVGEDINISFRTQGEP 2941
G D I R G P
Sbjct: 514 TAIAGRDTYIHCRVIGYP 531
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/352 (23%), Positives = 136/352 (38%), Gaps = 47/352 (13%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
N++ + + NRYG T+ IG L +P I P ++K G +L+
Sbjct: 282 NIRPSDSGSYVCEVSNRYG------TAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLS 334
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
CSV G + W +NG + + N + L + + D G Y C
Sbjct: 335 CSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQCFVRKDKL 392
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
A Y ++ V+ D T P+ ++ V PV L C V
Sbjct: 393 SAQDYVQV-VLEDGT---------------------PKIISAFSEKVVSPAEPVSLMCNV 430
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQ-----DEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
G+P P ++W D + ++ Q L I+ + + DGGVY TA N++
Sbjct: 431 KGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSA 490
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G V + V +G A + P ++ + + G + I V YP + WY++
Sbjct: 491 GVVLYQARINV-RG-PASIRP-----MKNITAI-AGRDTYIHCRVIGYPYYSIKWYKNS- 541
Query: 3307 RLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L P + + +G ++L+ D G YTC + + STS V V
Sbjct: 542 NLLPFNHRQVAFENNGTLKLSDVQKEV-DEGEYTCNVLVQ-PQLSTSQSVHV 591
Score = 55.2 bits (127), Expect = 4e-06
Identities = 86/383 (22%), Positives = 152/383 (39%), Gaps = 58/383 (15%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT---WYRNGVLLDNKLKYRKKLVDGL 2648
R+P ++ + D+ + G+ C + SS + +T W ++ V L + ++ L
Sbjct: 123 REP-YTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGAL 181
Query: 2649 ITLEVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-- 2705
+V N Y C + G S + +++ S A+ P SI D F
Sbjct: 182 YIKDVQNE--DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAP-----SILDGFDHR 234
Query: 2706 --LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+A + L C+ G P P W KD+ + GR+Q V L I+N P DSG
Sbjct: 235 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKT-----VTGLLIENIRPSDSG 289
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
+Y C+ N T ++ GR P K I+ + ++S
Sbjct: 290 SYVCEVSNRYGTAKV------IGRLYVKQP-----LKATISPRKVKS------------- 325
Query: 2824 VARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
+ G + L + G + + W R G + +N R+ L + + +++ G
Sbjct: 326 -SVGSQVSLSCSVTGTEDQELSWYRNG-EILNPGKNVRI-TGINHENLIMDHMVKSDGGA 382
Query: 2883 YTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
Y C D +A VQ DG P +I EK ++S E +++ +G P
Sbjct: 383 YQCFV-----RKDKLSAQDYVQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPL 435
Query: 2943 PKAVPERIPGEPCVVDGGNNWVS 2965
P + + +P ++ GG++ +S
Sbjct: 436 P-TITWTLDDDP-ILKGGSHRIS 456
Score = 54.8 bits (126), Expect = 5e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 24/196 (12%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE-- 2652
+ S F +++ V L C+V + PT+TW + D LK + +IT E
Sbjct: 409 IISAF-SEKVVSPAEPVSLMCNVKGTPLPTITWTLDD---DPILKGGSHRISQMITSEGN 464
Query: 2653 ---VLNAVPS---DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
LN S D Y CT N G + A + V P R +++ +
Sbjct: 465 VVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG--------PASIRPMKNITAI 516
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + + CR+ G P I W+K+ +P + R AF +G +L+ D D G YT
Sbjct: 517 AGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLS-DVQKEVDEGEYT 574
Query: 2767 CK--AENSVWTDQITH 2780
C + + T Q H
Sbjct: 575 CNVLVQPQLSTSQSVH 590
Score = 49.2 bits (112), Expect = 3e-04
Identities = 50/207 (24%), Positives = 75/207 (36%), Gaps = 17/207 (8%)
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R+ A V L C+ +G P P W KD + R K L I D G
Sbjct: 234 RKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQK----TVTGLLIENIRPSDSG 289
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y N G L V + ++A ++P K G ++ +S V
Sbjct: 290 SYVCEVSNRYGTAKVIGRLYVKQPLKATISPR-------KVKSSVGSQVSLSCSVTGTED 342
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
++WYR+G L P + +T L + + D G Y C + + S V
Sbjct: 343 QELSWYRNGEILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKD--KLSAQDYV 398
Query: 3357 EVIGTDQTSE--PRIPPVVISPDVPYS 3381
+V+ D T + V+SP P S
Sbjct: 399 QVVLEDGTPKIISAFSEKVVSPAEPVS 425
Score = 48.8 bits (111), Expect = 3e-04
Identities = 68/292 (23%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
+AG + C V G P + W KN + + ++ + NG L + D+ + DEG
Sbjct: 516 IAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNG---TLKLSDVQKEVDEGE 572
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C +L +S V PP F R
Sbjct: 573 YTCNVL----------------------VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSI 609
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
V + C V+ G P ++W KDG + + +L I+ +L G Y
Sbjct: 610 GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC 669
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
ARN + AV L+V + V P G+ G + ++ E YP +
Sbjct: 670 IARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY-------GKAVILNCSAEGYPVPTIV 722
Query: 3301 W-YRDGVRLRPSRRAIMTLDRDGQIE---LALAAVTTRDAGVYTCTASNEVG 3348
W + G + P + I R + L + V D+G Y C SN+VG
Sbjct: 723 WKFSKGAGV-PQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 773
Score = 48.0 bits (109), Expect = 6e-04
Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 12/187 (6%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
+R + R P + + TA+ G + C VI ++ WY+N LL +R+ +
Sbjct: 497 ARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFE 554
Query: 2647 GLITLEVLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
TL++ + D EY+C V + +STS ++ V +PP F
Sbjct: 555 NNGTLKLSDVQKEVDEGEYTCNVLVQ-PQLSTSQSVHV-----TVKVPPFIQPFEFPRFS 608
Query: 2706 LAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ + + + C + LP ITW KD + IP + D L I N + +G
Sbjct: 609 IGQ-RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI-DFTSSLRISNLSLMHNGN 666
Query: 2765 YTCKAEN 2771
YTC A N
Sbjct: 667 YTCIARN 673
Score = 46.8 bits (106), Expect = 0.001
Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 22/196 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLI--- 2649
P F D+ + G V L CS PT+ W + G + +++ ++G I
Sbjct: 690 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVP---QFQPIALNGRIQVL 746
Query: 2650 ---TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
+L + + V DS Y C V N+ GA +S S L V IP T T
Sbjct: 747 SNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV-------KIPAMITSYPNTTLA 799
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADG---VCRLAIDNPTPED 2761
+ + C G+ + W K+D+ I P RY G + L I ED
Sbjct: 800 TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVRED 859
Query: 2762 SGTYTCKAENSVWTDQ 2777
SG ++C A NS D+
Sbjct: 860 SGFFSCHAINSYGEDR 875
Score = 44.8 bits (101), Expect = 0.006
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 8/73 (10%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPS----DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
++VL C+ G P P + W KD PS DGR F + R EDSG Y
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV----KAEDSGYY 1357
Query: 2766 TCKAENSVWTDQI 2778
+C A N+ +D+I
Sbjct: 1358 SCIANNNWGSDEI 1370
Score = 38.7 bits (86), Expect = 0.36
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL + +Y V G G SS+ I V P + G + + L
Sbjct: 1250 NLSRNRQYSVWVVAVTSAGRGNSSEI---ITVEPLAKAPARILTFSGTVTTPWMKDIVLP 1306
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEA---GRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
C G P P V WMK+ + GR + NG I+ + +D G YSC A N
Sbjct: 1307 CKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG---SFIIRTVKAEDSGYYSCIANN 1363
Query: 3129 THGKASTYARLAV 3141
G L V
Sbjct: 1364 NWGSDEIILNLQV 1376
Score = 37.9 bits (84), Expect = 0.64
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEA-----GRMTSQFN 3103
P+FV + P + G+ L CS +G PVP +VW G V + GR+ N
Sbjct: 690 PKFV-VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 748
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHG 3131
G L IK + +D G Y C+ +N G
Sbjct: 749 G---SLLIKHVVEEDSGYYLCKVSNDVG 773
Score = 37.9 bits (84), Expect = 0.64
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEE----VVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L C+ +G P P V W KD V D RR+ + + F I +D G Y A
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF---IIRTVKAEDSGYYSCIA 1361
Query: 3243 RNNSGA 3248
NN G+
Sbjct: 1362 NNNWGS 1367
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1896
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/348 (23%), Positives = 140/348 (40%), Gaps = 43/348 (12%)
Query: 3019 YHFRVTPRNRYGWGESSQTSSS--IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKG 3076
Y++R R+RY GE+ Q++S+ A P +D + K +AG+ L C G
Sbjct: 179 YNYRCITRHRYT-GETRQSNSARLFVSDPANSAPSILDGFDHR-KAMAGQRVELPCKALG 236
Query: 3077 KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
P P W+K+ +E +GR G L I++I D G Y CE +N +G A
Sbjct: 237 HPEPDYRWLKDNMPLEL-SGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVI 291
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPP 3196
RL V P + T+ R + V L+C V G+
Sbjct: 292 GRLYV-----------------------KQPLKATISPRKVKSSVGSQVSLSCSVTGTED 328
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++SWY++G E++ + + L + DGG Y+ R + + + +V
Sbjct: 329 QELSWYRNG-EILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVV 387
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG--VRLRPSRRA 3314
++ G P+ + + + + V+ P +TW D + S R
Sbjct: 388 LEDG-----TPKIISAFSEKV-VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 441
Query: 3315 IMTLDRDGQI--ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ +G + L +++ RD GVY CTA+N G ++ V G
Sbjct: 442 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG 489
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/191 (29%), Positives = 81/191 (42%), Gaps = 20/191 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F R ++ G RV + C V+S P T+TW ++G + L +D +L
Sbjct: 583 PFIQPFEFPRFSI-GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLR 641
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N + Y+C NE A+ + L V +PP F RD + ++
Sbjct: 642 ISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR-------VPPKFVVQPRDQDGIYGKAVI 694
Query: 2713 LECRIRGQPLPKITW-FKDDKQIPS------DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L C G P+P I W F +P +GR Q L++G L I + EDSG Y
Sbjct: 695 LNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQV--LSNG--SLLIKHVVEEDSGYY 750
Query: 2766 TCKAENSVWTD 2776
CK N V D
Sbjct: 751 LCKVSNDVGAD 761
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK 2642
+ + R ++P+ +T + GS+V L+CSV + D ++WYRNG +L+ R
Sbjct: 289 KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 348
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
++ L + + V SD Y C V + +S ++V I F+ +
Sbjct: 349 TGINH-ENLIMDHMVKSDGGAYQCFVRKDK--LSAQDYVQVVLEDGTPKIISAFSEKVVS 405
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPT 2758
AE + L C ++G PLP ITW DD I G R ++G V L I +
Sbjct: 406 P---AE-PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 461
Query: 2759 PEDSGTYTCKAENS 2772
D G Y C A NS
Sbjct: 462 VRDGGVYRCTANNS 475
Score = 62.5 bits (145), Expect = 3e-08
Identities = 84/378 (22%), Positives = 147/378 (38%), Gaps = 51/378 (13%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
R + E R S + +S + P R A+ G RV+L C + +P W
Sbjct: 186 RHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWL 245
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
++ + L+ ++ +K V GL+ + N PSDS Y C V N G L V +
Sbjct: 246 KDNMPLELSGRF-QKTVTGLL---IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 301
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ P R ++ + +++ L C + G +++W+++ +I + G+
Sbjct: 302 ATISP----RKVKSS---VGSQVSLSCSVTGTEDQELSWYRNG-EILNPGK-NVRITGIN 352
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
L +D+ D G Y C FV +Q VV L
Sbjct: 353 HENLIMDHMVKSDGGAYQC-------------FVRKDKLSAQDYVQVV-----------L 388
Query: 2809 ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTE--VYRNARVFVEQ 2865
E P + ++ V+ + L ++G P + W + + + +R +++ +
Sbjct: 389 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 448
Query: 2866 G--LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G + L +S + G+Y C A ++ G V A I V P+ + RP K+I
Sbjct: 449 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI---------RPMKNI 499
Query: 2924 LISVGEDINISFRTQGEP 2941
G D I R G P
Sbjct: 500 TAIAGRDTYIHCRVIGYP 517
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/352 (23%), Positives = 136/352 (38%), Gaps = 47/352 (13%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
N++ + + NRYG T+ IG L +P I P ++K G +L+
Sbjct: 268 NIRPSDSGSYVCEVSNRYG------TAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLS 320
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
CSV G + W +NG + + N + L + + D G Y C
Sbjct: 321 CSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQCFVRKDKL 378
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
A Y ++ V+ D T P+ ++ V PV L C V
Sbjct: 379 SAQDYVQV-VLEDGT---------------------PKIISAFSEKVVSPAEPVSLMCNV 416
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQ-----DEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
G+P P ++W D + ++ Q L I+ + + DGGVY TA N++
Sbjct: 417 KGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSA 476
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G V + V +G A + P ++ + + G + I V YP + WY++
Sbjct: 477 GVVLYQARINV-RG-PASIRP-----MKNITAI-AGRDTYIHCRVIGYPYYSIKWYKNS- 527
Query: 3307 RLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L P + + +G ++L+ D G YTC + + STS V V
Sbjct: 528 NLLPFNHRQVAFENNGTLKLSDVQKEV-DEGEYTCNVLVQ-PQLSTSQSVHV 577
Score = 55.2 bits (127), Expect = 4e-06
Identities = 86/383 (22%), Positives = 152/383 (39%), Gaps = 58/383 (15%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT---WYRNGVLLDNKLKYRKKLVDGL 2648
R+P ++ + D+ + G+ C + SS + +T W ++ V L + ++ L
Sbjct: 109 REP-YTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGAL 167
Query: 2649 ITLEVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-- 2705
+V N Y C + G S + +++ S A+ P SI D F
Sbjct: 168 YIKDVQNE--DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAP-----SILDGFDHR 220
Query: 2706 --LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+A + L C+ G P P W KD+ + GR+Q V L I+N P DSG
Sbjct: 221 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKT-----VTGLLIENIRPSDSG 275
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
+Y C+ N T ++ GR P K I+ + ++S
Sbjct: 276 SYVCEVSNRYGTAKV------IGRLYVKQP-----LKATISPRKVKS------------- 311
Query: 2824 VARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
+ G + L + G + + W R G + +N R+ L + + +++ G
Sbjct: 312 -SVGSQVSLSCSVTGTEDQELSWYRNG-EILNPGKNVRI-TGINHENLIMDHMVKSDGGA 368
Query: 2883 YTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
Y C D +A VQ DG P +I EK ++S E +++ +G P
Sbjct: 369 YQCFV-----RKDKLSAQDYVQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPL 421
Query: 2943 PKAVPERIPGEPCVVDGGNNWVS 2965
P + + +P ++ GG++ +S
Sbjct: 422 P-TITWTLDDDP-ILKGGSHRIS 442
Score = 54.8 bits (126), Expect = 5e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 24/196 (12%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE-- 2652
+ S F +++ V L C+V + PT+TW + D LK + +IT E
Sbjct: 395 IISAF-SEKVVSPAEPVSLMCNVKGTPLPTITWTLDD---DPILKGGSHRISQMITSEGN 450
Query: 2653 ---VLNAVPS---DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
LN S D Y CT N G + A + V P R +++ +
Sbjct: 451 VVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG--------PASIRPMKNITAI 502
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + + CR+ G P I W+K+ +P + R AF +G +L+ D D G YT
Sbjct: 503 AGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLS-DVQKEVDEGEYT 560
Query: 2767 CK--AENSVWTDQITH 2780
C + + T Q H
Sbjct: 561 CNVLVQPQLSTSQSVH 576
Score = 49.2 bits (112), Expect = 3e-04
Identities = 50/207 (24%), Positives = 75/207 (36%), Gaps = 17/207 (8%)
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R+ A V L C+ +G P P W KD + R K L I D G
Sbjct: 220 RKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQK----TVTGLLIENIRPSDSG 275
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y N G L V + ++A ++P K G ++ +S V
Sbjct: 276 SYVCEVSNRYGTAKVIGRLYVKQPLKATISPR-------KVKSSVGSQVSLSCSVTGTED 328
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
++WYR+G L P + +T L + + D G Y C + + S V
Sbjct: 329 QELSWYRNGEILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKD--KLSAQDYV 384
Query: 3357 EVIGTDQTSE--PRIPPVVISPDVPYS 3381
+V+ D T + V+SP P S
Sbjct: 385 QVVLEDGTPKIISAFSEKVVSPAEPVS 411
Score = 48.8 bits (111), Expect = 3e-04
Identities = 68/292 (23%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
+AG + C V G P + W KN + + ++ + NG L + D+ + DEG
Sbjct: 502 IAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNG---TLKLSDVQKEVDEGE 558
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C +L +S V PP F R
Sbjct: 559 YTCNVL----------------------VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSI 595
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
V + C V+ G P ++W KDG + + +L I+ +L G Y
Sbjct: 596 GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC 655
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
ARN + AV L+V + V P G+ G + ++ E YP +
Sbjct: 656 IARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY-------GKAVILNCSAEGYPVPTIV 708
Query: 3301 W-YRDGVRLRPSRRAIMTLDRDGQIE---LALAAVTTRDAGVYTCTASNEVG 3348
W + G + P + I R + L + V D+G Y C SN+VG
Sbjct: 709 WKFSKGAGV-PQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 759
Score = 48.0 bits (109), Expect = 6e-04
Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 12/187 (6%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
+R + R P + + TA+ G + C VI ++ WY+N LL +R+ +
Sbjct: 483 ARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFE 540
Query: 2647 GLITLEVLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
TL++ + D EY+C V + +STS ++ V +PP F
Sbjct: 541 NNGTLKLSDVQKEVDEGEYTCNVLVQ-PQLSTSQSVHV-----TVKVPPFIQPFEFPRFS 594
Query: 2706 LAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ + + + C + LP ITW KD + IP + D L I N + +G
Sbjct: 595 IGQ-RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI-DFTSSLRISNLSLMHNGN 652
Query: 2765 YTCKAEN 2771
YTC A N
Sbjct: 653 YTCIARN 659
Score = 46.8 bits (106), Expect = 0.001
Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 22/196 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLI--- 2649
P F D+ + G V L CS PT+ W + G + +++ ++G I
Sbjct: 676 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVP---QFQPIALNGRIQVL 732
Query: 2650 ---TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
+L + + V DS Y C V N+ GA +S S L V IP T T
Sbjct: 733 SNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV-------KIPAMITSYPNTTLA 785
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADG---VCRLAIDNPTPED 2761
+ + C G+ + W K+D+ I P RY G + L I ED
Sbjct: 786 TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVRED 845
Query: 2762 SGTYTCKAENSVWTDQ 2777
SG ++C A NS D+
Sbjct: 846 SGFFSCHAINSYGEDR 861
Score = 44.8 bits (101), Expect = 0.006
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 8/73 (10%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPS----DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
++VL C+ G P P + W KD PS DGR F + R EDSG Y
Sbjct: 1288 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV----KAEDSGYY 1343
Query: 2766 TCKAENSVWTDQI 2778
+C A N+ +D+I
Sbjct: 1344 SCIANNNWGSDEI 1356
Score = 38.7 bits (86), Expect = 0.36
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL + +Y V G G SS+ I V P + G + + L
Sbjct: 1236 NLSRNRQYSVWVVAVTSAGRGNSSEI---ITVEPLAKAPARILTFSGTVTTPWMKDIVLP 1292
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEA---GRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
C G P P V WMK+ + GR + NG I+ + +D G YSC A N
Sbjct: 1293 CKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG---SFIIRTVKAEDSGYYSCIANN 1349
Query: 3129 THGKASTYARLAV 3141
G L V
Sbjct: 1350 NWGSDEIILNLQV 1362
Score = 37.9 bits (84), Expect = 0.64
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEA-----GRMTSQFN 3103
P+FV + P + G+ L CS +G PVP +VW G V + GR+ N
Sbjct: 676 PKFV-VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 734
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHG 3131
G L IK + +D G Y C+ +N G
Sbjct: 735 G---SLLIKHVVEEDSGYYLCKVSNDVG 759
Score = 37.9 bits (84), Expect = 0.64
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEE----VVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L C+ +G P P V W KD V D RR+ + + F I +D G Y A
Sbjct: 1291 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF---IIRTVKAEDSGYYSCIA 1347
Query: 3243 RNNSGA 3248
NN G+
Sbjct: 1348 NNNWGS 1353
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhesion
molecule isoform CHD2-42 precursor variant protein.
Length = 2023
Score = 80.6 bits (190), Expect = 9e-14
Identities = 83/348 (23%), Positives = 140/348 (40%), Gaps = 43/348 (12%)
Query: 3019 YHFRVTPRNRYGWGESSQTSSS--IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKG 3076
Y++R R+RY GE+ Q++S+ A P +D + K +AG+ L C G
Sbjct: 204 YNYRCITRHRYT-GETRQSNSARLFVSDPANSAPSILDGFEHR-KAMAGQRVELPCKALG 261
Query: 3077 KPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTY 3136
P P W+K+ +E +GR G L I++I D G Y CE +N +G A
Sbjct: 262 HPEPDYRWLKDNMPLEL-SGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVI 316
Query: 3137 ARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPP 3196
RL V P + T+ R + V L+C V G+
Sbjct: 317 GRLYV-----------------------KQPLKATISPRKVKSSVGSQVSLSCSVTGTED 353
Query: 3197 PKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLV 3256
++SWY++G E++ + + L + DGG Y+ R + + + +V
Sbjct: 354 QELSWYRNG-EILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVV 412
Query: 3257 VDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG--VRLRPSRRA 3314
++ G P+ + + + + V+ P +TW D + S R
Sbjct: 413 LEDG-----TPKIISAFSEKV-VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 466
Query: 3315 IMTLDRDGQI--ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ +G + L +++ RD GVY CTA+N G ++ V G
Sbjct: 467 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG 514
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/191 (29%), Positives = 81/191 (42%), Gaps = 20/191 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F R ++ G RV + C V+S P T+TW ++G + L +D +L
Sbjct: 608 PFIQPFEFPRFSI-GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLR 666
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N + Y+C NE A+ + L V +PP F RD + ++
Sbjct: 667 ISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR-------VPPKFVVQPRDQDGIYGKAVI 719
Query: 2713 LECRIRGQPLPKITW-FKDDKQIPS------DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L C G P+P I W F +P +GR Q L++G L I + EDSG Y
Sbjct: 720 LNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQV--LSNG--SLLIKHVVEEDSGYY 775
Query: 2766 TCKAENSVWTD 2776
CK N V D
Sbjct: 776 LCKVSNDVGAD 786
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK 2642
+ + R ++P+ +T + GS+V L+CSV + D ++WYRNG +L+ R
Sbjct: 314 KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 373
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
++ L + + V SD Y C V + +S ++V I F+ +
Sbjct: 374 TGINH-ENLIMDHMVKSDGGAYQCFVRKDK--LSAQDYVQVVLEDGTPKIISAFSEKVVS 430
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPT 2758
AE + L C ++G PLP ITW DD I G R ++G V L I +
Sbjct: 431 P---AE-PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 486
Query: 2759 PEDSGTYTCKAENS 2772
D G Y C A NS
Sbjct: 487 VRDGGVYRCTANNS 500
Score = 62.5 bits (145), Expect = 3e-08
Identities = 84/378 (22%), Positives = 147/378 (38%), Gaps = 51/378 (13%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWY 2628
R + E R S + +S + P R A+ G RV+L C + +P W
Sbjct: 211 RHRYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAMAGQRVELPCKALGHPEPDYRWL 270
Query: 2629 RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFE 2688
++ + L+ ++ +K V GL+ + N PSDS Y C V N G L V +
Sbjct: 271 KDNMPLELSGRF-QKTVTGLL---IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 326
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ P R ++ + +++ L C + G +++W+++ +I + G+
Sbjct: 327 ATISP----RKVKSS---VGSQVSLSCSVTGTEDQELSWYRNG-EILNPGK-NVRITGIN 377
Query: 2749 VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSL 2808
L +D+ D G Y C FV +Q VV L
Sbjct: 378 HENLIMDHMVKSDGGAYQC-------------FVRKDKLSAQDYVQVV-----------L 413
Query: 2809 ESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTE--VYRNARVFVEQ 2865
E P + ++ V+ + L ++G P + W + + + +R +++ +
Sbjct: 414 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 473
Query: 2866 G--LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G + L +S + G+Y C A ++ G V A I V P+ + RP K+I
Sbjct: 474 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI---------RPMKNI 524
Query: 2924 LISVGEDINISFRTQGEP 2941
G D I R G P
Sbjct: 525 TAIAGRDTYIHCRVIGYP 542
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/352 (23%), Positives = 136/352 (38%), Gaps = 47/352 (13%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
N++ + + NRYG T+ IG L +P I P ++K G +L+
Sbjct: 293 NIRPSDSGSYVCEVSNRYG------TAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLS 345
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
CSV G + W +NG + + N + L + + D G Y C
Sbjct: 346 CSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQCFVRKDKL 403
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
A Y ++ V+ D T P+ ++ V PV L C V
Sbjct: 404 SAQDYVQV-VLEDGT---------------------PKIISAFSEKVVSPAEPVSLMCNV 441
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQ-----DEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
G+P P ++W D + ++ Q L I+ + + DGGVY TA N++
Sbjct: 442 KGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSA 501
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G V + V +G A + P ++ + + G + I V YP + WY++
Sbjct: 502 GVVLYQARINV-RG-PASIRP-----MKNITAI-AGRDTYIHCRVIGYPYYSIKWYKNS- 552
Query: 3307 RLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L P + + +G ++L+ D G YTC + + STS V V
Sbjct: 553 NLLPFNHRQVAFENNGTLKLSDVQKEV-DEGEYTCNVLVQ-PQLSTSQSVHV 602
Score = 55.6 bits (128), Expect = 3e-06
Identities = 86/383 (22%), Positives = 152/383 (39%), Gaps = 58/383 (15%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT---WYRNGVLLDNKLKYRKKLVDGL 2648
R+P ++ + D+ + G+ C + SS + +T W ++ V L + ++ L
Sbjct: 134 REP-YTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGAL 192
Query: 2649 ITLEVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-- 2705
+V N Y C + G S + +++ S A+ P SI D F
Sbjct: 193 YIKDVQNE--DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAP-----SILDGFEHR 245
Query: 2706 --LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+A + L C+ G P P W KD+ + GR+Q V L I+N P DSG
Sbjct: 246 KAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKT-----VTGLLIENIRPSDSG 300
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
+Y C+ N T ++ GR P K I+ + ++S
Sbjct: 301 SYVCEVSNRYGTAKV------IGRLYVKQP-----LKATISPRKVKS------------- 336
Query: 2824 VARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGL 2882
+ G + L + G + + W R G + +N R+ L + + +++ G
Sbjct: 337 -SVGSQVSLSCSVTGTEDQELSWYRNG-EILNPGKNVRI-TGINHENLIMDHMVKSDGGA 393
Query: 2883 YTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
Y C D +A VQ DG P +I EK ++S E +++ +G P
Sbjct: 394 YQCFV-----RKDKLSAQDYVQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPL 446
Query: 2943 PKAVPERIPGEPCVVDGGNNWVS 2965
P + + +P ++ GG++ +S
Sbjct: 447 P-TITWTLDDDP-ILKGGSHRIS 467
Score = 54.8 bits (126), Expect = 5e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 24/196 (12%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE-- 2652
+ S F +++ V L C+V + PT+TW + D LK + +IT E
Sbjct: 420 IISAF-SEKVVSPAEPVSLMCNVKGTPLPTITWTLDD---DPILKGGSHRISQMITSEGN 475
Query: 2653 ---VLNAVPS---DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
LN S D Y CT N G + A + V P R +++ +
Sbjct: 476 VVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG--------PASIRPMKNITAI 527
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + + CR+ G P I W+K+ +P + R AF +G +L+ D D G YT
Sbjct: 528 AGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLS-DVQKEVDEGEYT 585
Query: 2767 CK--AENSVWTDQITH 2780
C + + T Q H
Sbjct: 586 CNVLVQPQLSTSQSVH 601
Score = 49.2 bits (112), Expect = 3e-04
Identities = 50/207 (24%), Positives = 75/207 (36%), Gaps = 17/207 (8%)
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R+ A V L C+ +G P P W KD + R K L I D G
Sbjct: 245 RKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQK----TVTGLLIENIRPSDSG 300
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y N G L V + ++A ++P K G ++ +S V
Sbjct: 301 SYVCEVSNRYGTAKVIGRLYVKQPLKATISPR-------KVKSSVGSQVSLSCSVTGTED 353
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
++WYR+G L P + +T L + + D G Y C + + S V
Sbjct: 354 QELSWYRNGEILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKD--KLSAQDYV 409
Query: 3357 EVIGTDQTSE--PRIPPVVISPDVPYS 3381
+V+ D T + V+SP P S
Sbjct: 410 QVVLEDGTPKIISAFSEKVVSPAEPVS 436
Score = 48.8 bits (111), Expect = 3e-04
Identities = 68/292 (23%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
+AG + C V G P + W KN + + ++ + NG L + D+ + DEG
Sbjct: 527 IAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNG---TLKLSDVQKEVDEGE 583
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C +L +S V PP F R
Sbjct: 584 YTCNVL----------------------VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSI 620
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
V + C V+ G P ++W KDG + + +L I+ +L G Y
Sbjct: 621 GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC 680
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
ARN + AV L+V + V P G+ G + ++ E YP +
Sbjct: 681 IARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY-------GKAVILNCSAEGYPVPTIV 733
Query: 3301 W-YRDGVRLRPSRRAIMTLDRDGQIE---LALAAVTTRDAGVYTCTASNEVG 3348
W + G + P + I R + L + V D+G Y C SN+VG
Sbjct: 734 WKFSKGAGV-PQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 784
Score = 48.0 bits (109), Expect = 6e-04
Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 12/187 (6%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
+R + R P + + TA+ G + C VI ++ WY+N LL +R+ +
Sbjct: 508 ARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFE 565
Query: 2647 GLITLEVLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
TL++ + D EY+C V + +STS ++ V +PP F
Sbjct: 566 NNGTLKLSDVQKEVDEGEYTCNVLVQ-PQLSTSQSVHV-----TVKVPPFIQPFEFPRFS 619
Query: 2706 LAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ + + + C + LP ITW KD + IP + D L I N + +G
Sbjct: 620 IGQ-RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI-DFTSSLRISNLSLMHNGN 677
Query: 2765 YTCKAEN 2771
YTC A N
Sbjct: 678 YTCIARN 684
Score = 46.8 bits (106), Expect = 0.001
Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 22/196 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLI--- 2649
P F D+ + G V L CS PT+ W + G + +++ ++G I
Sbjct: 701 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVP---QFQPIALNGRIQVL 757
Query: 2650 ---TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
+L + + V DS Y C V N+ GA +S S L V IP T T
Sbjct: 758 SNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV-------KIPAMITSYPNTTLA 810
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADG---VCRLAIDNPTPED 2761
+ + C G+ + W K+D+ I P RY G + L I ED
Sbjct: 811 TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVRED 870
Query: 2762 SGTYTCKAENSVWTDQ 2777
SG ++C A NS D+
Sbjct: 871 SGFFSCHAINSYGEDR 886
Score = 44.8 bits (101), Expect = 0.006
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 8/73 (10%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPS----DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
++VL C+ G P P + W KD PS DGR F + R EDSG Y
Sbjct: 1313 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV----KAEDSGYY 1368
Query: 2766 TCKAENSVWTDQI 2778
+C A N+ +D+I
Sbjct: 1369 SCIANNNWGSDEI 1381
Score = 38.7 bits (86), Expect = 0.36
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL + +Y V G G SS+ I V P + G + + L
Sbjct: 1261 NLSRNRQYSVWVVAVTSAGRGNSSEI---ITVEPLAKAPARILTFSGTVTTPWMKDIVLP 1317
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEA---GRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
C G P P V WMK+ + GR + NG I+ + +D G YSC A N
Sbjct: 1318 CKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG---SFIIRTVKAEDSGYYSCIANN 1374
Query: 3129 THGKASTYARLAV 3141
G L V
Sbjct: 1375 NWGSDEIILNLQV 1387
Score = 37.9 bits (84), Expect = 0.64
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEA-----GRMTSQFN 3103
P+FV + P + G+ L CS +G PVP +VW G V + GR+ N
Sbjct: 701 PKFV-VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 759
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHG 3131
G L IK + +D G Y C+ +N G
Sbjct: 760 G---SLLIKHVVEEDSGYYLCKVSNDVG 784
Score = 37.9 bits (84), Expect = 0.64
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEE----VVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L C+ +G P P V W KD V D RR+ + + F I +D G Y A
Sbjct: 1316 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF---IIRTVKAEDSGYYSCIA 1372
Query: 3243 RNNSGA 3248
NN G+
Sbjct: 1373 NNNWGS 1378
>BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein.
Length = 1212
Score = 80.2 bits (189), Expect = 1e-13
Identities = 119/474 (25%), Positives = 185/474 (39%), Gaps = 52/474 (10%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKL----KYRKKLVDG 2647
R P F L E + V LTC+V +S P VTWY+N +D +L KYR G
Sbjct: 152 RGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYG 211
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV---------YPS--FEASPIPPT- 2695
L++LE+ DSA Y+ V+N +G S+ A + V + S F+ S P+
Sbjct: 212 LLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSV 271
Query: 2696 -FTRSIRDTFHLAENELVLECRIRGQPL--PKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
FT ++ F + L C L I WF+D + S R + Y D L
Sbjct: 272 EFTSVLKPVFAREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILY-TDRQASL 330
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
+ ED G Y + + + + +V E++ +P A + + + L+ R
Sbjct: 331 KVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAE-NPG---APGSPLNVRCLDVNR 386
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLAL 2872
RG I R EW+ A G +
Sbjct: 387 DCLILTWAPPSDTRGNPITAYTIERCQGESGEWI------------ACHEAPGGTCRCPI 434
Query: 2873 SDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
+ E +S + RA S G+ + A +V D D R + +I +G I
Sbjct: 435 QGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHD------AARRKTEIPFDLGNKIT 488
Query: 2933 ISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAE 2992
IS T +P P + +V LAW + P+ AP L Y +E +IG+
Sbjct: 489 IS--TDAFEDTVTIPSP-PTNVHASEIREAYVVLAWEEPSPRGRAP-LTYSLEKSVIGS- 543
Query: 2993 GGARWVELGI-TPLNS--FDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGV 3043
W + +P+ S F +L++ + Y FRV N+YG + S+ S I +
Sbjct: 544 --GTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIAL 595
Score = 64.1 bits (149), Expect = 8e-09
Identities = 48/179 (26%), Positives = 78/179 (43%), Gaps = 8/179 (4%)
Query: 3067 TANLTCSVKGKPVPGVVWMKNGHEVEEE---AGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
T LTC+V+ P P V W KN ++ AG+ N L I+ I+D Y+
Sbjct: 170 TVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYT 229
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
N HG+AS++A++ V RT DA E +FT L+ +
Sbjct: 230 VRVKNAHGQASSFAKVLV---RTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKE 286
Query: 3184 PVRLTCQVIGS--PPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
P L+C + W++DG + +RR ++ +L+++ T +D G+Y V
Sbjct: 287 PFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMV 345
Score = 62.9 bits (146), Expect = 2e-08
Identities = 61/211 (28%), Positives = 89/211 (42%), Gaps = 22/211 (10%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQFH--- 3223
P F + LR V V LTC V SPPP+V+WYK+ + R KY+ +
Sbjct: 154 PWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLL 213
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV------DKGI------RAYVAP--EF 3269
+LEI ++D Y V +N G S ++V D G R+ P EF
Sbjct: 214 SLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSVEF 273
Query: 3270 CCGLEPLYKLHEGDELRISAVV--EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELA 3327
L+P++ E + +S + + + + W+RDG LR SRR L D Q L
Sbjct: 274 TSVLKPVF-AREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRR-KILYTDRQASLK 331
Query: 3328 LAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
++ D G+Y + G S V V
Sbjct: 332 VSCTYKEDEGLYMVRVPSPFGPREQSTYVLV 362
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat protein
LRIG1 protein.
Length = 1093
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/252 (26%), Positives = 103/252 (40%), Gaps = 33/252 (13%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L ++ + EGRY C TN G STY+ A +T + P
Sbjct: 562 LHLRQVTFGHEGRYQCVITNHFG--STYSHKARLTVNVL--------------------P 599
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLEI 3227
FT D ++ T RL C G P P+++W KD G + + R + I
Sbjct: 600 SFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFI 659
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+DD GVY TA+N++G++S + L V P LE + G+ + +
Sbjct: 660 TDVKIDDAGVYSCTAQNSAGSISANATLTV------LETPSLVVPLEDRV-VSVGETVAL 712
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
P +TW++ L + R +T D Q+ L + V DAG YTC SN +
Sbjct: 713 QCKATGNPPPRITWFKGDRPLSLTERHHLT--PDNQL-LVVQNVVAEDAGRYTCEMSNTL 769
Query: 3348 GRASTSGKVEVI 3359
G ++ V+
Sbjct: 770 GTERAHSQLSVL 781
Score = 74.1 bits (174), Expect = 8e-12
Identities = 55/201 (27%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK 2637
S S K L+ N P F+ D T + +L C+ +P + W ++G
Sbjct: 585 STYSHKARLTVNVL--PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPA 642
Query: 2638 LKYRKKLVDGLITLEVLNAVPSDSAE-YSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
+ R+ V + + V D A YSCT +N G+IS +A L V + P+
Sbjct: 643 ARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLET-------PSL 695
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
+ D + L+C+ G P P+ITWFK D+ + R+ +L L + N
Sbjct: 696 VVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERH---HLTPDNQLLVVQN 752
Query: 2757 PTPEDSGTYTCKAENSVWTDQ 2777
ED+G YTC+ N++ T++
Sbjct: 753 VVAEDAGRYTCEMSNTLGTER 773
Score = 72.9 bits (171), Expect = 2e-11
Identities = 63/242 (26%), Positives = 88/242 (36%), Gaps = 31/242 (12%)
Query: 3016 GEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVK 3075
G E ++ N +G S + ++ V P F P + I A L C+
Sbjct: 570 GHEGRYQCVITNHFGSTYSHKARLTVNV-----LPSFTKT-PHDITIRTTTVARLECAAT 623
Query: 3076 GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAST 3135
G P P + W K+G A D I D+ IDD G YSC A N+ G S
Sbjct: 624 GHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISA 683
Query: 3136 YARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSP 3195
A L V+ P + L DR V V L C+ G+P
Sbjct: 684 NATLTVLE-----------------------TPSLVVPLEDRVVSVGETVALQCKATGNP 720
Query: 3196 PPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL 3255
PP+++W+K + +R + D Q L + +D G Y N G H L
Sbjct: 721 PPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCEMSNTLGTERAHSQL 778
Query: 3256 VV 3257
V
Sbjct: 779 SV 780
Score = 52.4 bits (120), Expect = 3e-05
Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + L+ G P ++ W ++G + R R+ V
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
++DV ++G+Y+C A ++ G++ NA +TV++ P+++V P +D ++SVGE +
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLE------TPSLVV--PLEDRVVSVGETV 710
Query: 2932 NISFRTQGEPKPK 2944
+ + G P P+
Sbjct: 711 ALQCKATGNPPPR 723
Score = 51.2 bits (117), Expect = 6e-05
Identities = 76/323 (23%), Positives = 121/323 (37%), Gaps = 47/323 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLLDN---KLKYRKKLVDG 2647
KP T A+ G ++ TCS SSS +T W ++ +L N + DG
Sbjct: 494 KPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDG 553
Query: 2648 LI-----TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L + Y C + N G+ S A L V + P+FT++
Sbjct: 554 EVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTV-------NVLPSFTKTPH 606
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
D LEC G P P+I W KD R + ++ I + +D
Sbjct: 607 DITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDD 666
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+G Y+C A+NS +S N LE+ P L D
Sbjct: 667 AGVYSCTAQNSA---------------GSISANATLT--------VLET--PSLVVPLED 701
Query: 2822 YQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V+ G T+ LQ + G P R+ W + R ++ R+ Q L + +V ++
Sbjct: 702 RVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQ---LLVVQNVVAEDA 758
Query: 2881 GLYTCRAWSAHGNVDMNAAITVV 2903
G YTC + G ++ ++V+
Sbjct: 759 GRYTCEMSNTLGTERAHSQLSVL 781
Score = 48.0 bits (109), Expect = 6e-04
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET L C G P P + W K + + N L ++++ +D GR
Sbjct: 704 VSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL---LVVQNVVAEDAGR 760
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y+CE +NT G +++L+V+
Sbjct: 761 YTCEMSNTLGTERAHSQLSVL 781
Score = 46.4 bits (105), Expect = 0.002
Identities = 57/246 (23%), Positives = 90/246 (36%), Gaps = 40/246 (16%)
Query: 3185 VRLTCQVIGSP--PPKVSWYKDGEEVVYDKRRN----KYQD----EQFHTLEIAPTNLDD 3234
+R TC S P +W KD E + N QD E L +
Sbjct: 512 IRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGH 571
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y+ N+ G+ H + V P F + + R+ +
Sbjct: 572 EGRYQCVITNHFGSTYSH-----KARLTVNVLPSFTKTPHDI-TIRTTTVARLECAATGH 625
Query: 3295 PSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
P+ + W +DG P+ R M + D + + V DAGVY+CTA N G S +
Sbjct: 626 PNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQNSAGSISAN 684
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ T P +V VP + + G+TV ++C+ G+P P
Sbjct: 685 ATLTVLET--------PSLV----VPLEDRVVSV----------GETVALQCKATGNPPP 722
Query: 3414 DVYWLR 3419
+ W +
Sbjct: 723 RITWFK 728
>AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing
glycosylphosphatidylinositol anchor 2 protein.
Length = 956
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/205 (32%), Positives = 95/205 (46%), Gaps = 28/205 (13%)
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK---LH 3280
TL I DD G Y A NN G + ++ +RA F +P +K +
Sbjct: 294 TLTIPAITSDDAGTYSCIANNNVGNPAKKSTNII---VRALKKGRFWITPDPYHKDDNIQ 350
Query: 3281 EGDELRISAVVEAYPSVGVT--WYRDGVRLRPSRRAIMT-LDRD---GQIELALAAVTTR 3334
G E++IS VEA PS +T W+++G LR S R ++T D D G L + +
Sbjct: 351 IGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFT 410
Query: 3335 DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE 3394
D G YTC AS + G S ++V S +PP + VP K P+
Sbjct: 411 DFGTYTCVASLKGGGISDIS-IDV----NISSSTVPPNLT---VPQEKSPLV-------- 454
Query: 3395 AREGDTVIIECEVVGDPKPDVYWLR 3419
REGDT+ ++C+V G PKP + W R
Sbjct: 455 TREGDTIELQCQVTGKPKPIILWSR 479
Score = 61.7 bits (143), Expect = 5e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 14/170 (8%)
Query: 2608 GSRVKLTCSV--ISSSDPTVTWYRNGVLLDNKLKYRKKLVD-----GLITLEVLNAVPSD 2660
G VK++C V + S + T +W++NG L + + D G L++++ +D
Sbjct: 352 GREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTD 411
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT-RSIRDTFHLAENELV-LECRIR 2718
Y+C + G IS ++ + + +S +PP T + E + + L+C++
Sbjct: 412 FGTYTCVASLKGGGIS---DISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVT 468
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
G+P P I W + DK++ DG R+ N + E SG Y C+
Sbjct: 469 GKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIV--NVSREMSGMYRCQ 516
Score = 55.2 bits (127), Expect = 4e-06
Identities = 75/317 (23%), Positives = 122/317 (38%), Gaps = 36/317 (11%)
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L++ N P D A YSC N + + V P+ + D + E
Sbjct: 201 LKLKNLRPQDYANYSCIASVRN--VCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGE 258
Query: 2711 LV-LEC-RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ L C G+P P +TW + +P + L G L I T +D+GTY+C
Sbjct: 259 AITLVCVTTGGEPAPSLTWVRSFGTLP-----EKTVLNGGT--LTIPAITSDDAGTYSCI 311
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A N+V G ++ S N++ R ++ P + + Q+ R
Sbjct: 312 ANNNV------------GNPAKKSTNII----VRALKKGRFWITPDPYHKDDNIQIGREV 355
Query: 2829 TIGLQVE-IRGCPTRVEWLREGR----SVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
I QVE + W + GR S V V G L + D+ T+ G Y
Sbjct: 356 KISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTY 415
Query: 2884 TCRAWSAHGNV-DMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
TC A G + D++ + + S P + V + + ++ G+ I + + G+PK
Sbjct: 416 TCVASLKGGGISDISIDVNI---SSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPK 472
Query: 2943 PKAVPERIPGEPCVVDG 2959
P + R E + DG
Sbjct: 473 PIILWSRADKEVAMPDG 489
Score = 52.0 bits (119), Expect = 4e-05
Identities = 53/207 (25%), Positives = 90/207 (43%), Gaps = 31/207 (14%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+T L C V GKP P ++W + EV G M Q +D L I +++ + G Y C
Sbjct: 458 GDTIELQCQVTGKPKPIILWSRADKEVAMPDGSM--QMESYDGTLRIVNVSREMSGMYRC 515
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+ + +G + K RE ++ YPP + R
Sbjct: 516 QTSQYNG------------------FNVK-PREALVQLIVQYPPAVEPAFLEIRQGQDRS 556
Query: 3185 VRLTCQVIGSPPPKVSWY--KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
V ++C+V+ + P +V Y + G +++ R ++ +++ + + ++ GVY +
Sbjct: 557 VTMSCRVLRAYPIRVLTYEWRLGNKLL---RTGQFDSQEYTEYAVKSLSNENYGVYNCSI 613
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
N +GA C LV K AY APEF
Sbjct: 614 INEAGAGRCSF-LVTGK---AY-APEF 635
Score = 45.6 bits (103), Expect = 0.003
Identities = 72/307 (23%), Positives = 124/307 (40%), Gaps = 47/307 (15%)
Query: 3062 ILAGETANLTCSVKGKPVPGVV--WMKNGHEVEEEAGRMTSQ----FNGFDCCLTIKDIN 3115
I G ++C V+ P + W KNG + + +Q + L I D+
Sbjct: 349 IQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLK 408
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEV--EGDYPPQFTMR 3173
D G Y+C A+ G S + ++ TV + + +E+S V EGD
Sbjct: 409 FTDFGTYTCVASLKGGGISDISIDVNISSSTV-PPNLTVPQEKSPLVTREGD-------- 459
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLEIAPTNL 3232
+ L CQV G P P + W + +EV Q E + TL I +
Sbjct: 460 ----------TIELQCQVTGKPKPIILWSRADKEVAMPD--GSMQMESYDGTLRIVNVSR 507
Query: 3233 DDGGVYEV-TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY-KLHEGDELRIS-- 3288
+ G+Y T++ N V LV + ++ +EP + ++ +G + ++
Sbjct: 508 EMSGMYRCQTSQYNGFNVKPREALV-------QLIVQYPPAVEPAFLEIRQGQDRSVTMS 560
Query: 3289 -AVVEAYPSVGVTW-YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
V+ AYP +T+ +R G +L + + D E A+ +++ + GVY C+ NE
Sbjct: 561 CRVLRAYPIRVLTYEWRLGNKLLRTGQ----FDSQEYTEYAVKSLSNENYGVYNCSIINE 616
Query: 3347 VGRASTS 3353
G S
Sbjct: 617 AGAGRCS 623
Score = 44.0 bits (99), Expect = 0.010
Identities = 74/295 (25%), Positives = 116/295 (39%), Gaps = 37/295 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
I GET LTC V G P P + W K + + +S FN L I +I GR
Sbjct: 52 IREGETLELTCLVTGHPRPQIRWTKTAGSASDRF-QDSSVFNE---TLRITNIQRHQGGR 107
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C+A N G A ++ D + + E + + + T+ LR
Sbjct: 108 YYCKAENGLGSP---AIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLR------ 158
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVY---DKRRNKYQD--EQFHTLEIAPTNL--DD 3234
C +PP + SW + G+EV+ DK Y+ Q T + NL D
Sbjct: 159 -------CVANSNPPVRYSW-RRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQD 210
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVE-A 3293
Y A + + +V + +P ++ ++ G+ + + V
Sbjct: 211 YANYSCIA-SVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGG 269
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P+ +TW R L P + T+ G L + A+T+ DAG Y+C A+N VG
Sbjct: 270 EPAPSLTWVRSFGTL-PEK----TVLNGG--TLTIPAITSDDAGTYSCIANNNVG 317
Score = 41.5 bits (93), Expect = 0.052
Identities = 72/346 (20%), Positives = 131/346 (37%), Gaps = 39/346 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG ++LTC V P + W + ++ + + TL + N
Sbjct: 51 TIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNE---TLRITNIQRHQGGR 107
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSI---RDTFHLAENELVLECRIRGQ 2720
Y C EN G+ + +++V + P+ T +SI ++ F+ E + L C
Sbjct: 108 YYCKAENGLGSPAIK-SIRVDVYYLDDPV-VTVHQSIGEAKEQFYY-ERTVFLRCVANSN 164
Query: 2721 PLPKITWFKDDKQI--PSDGR---YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWT 2775
P + +W + + + SD Y+ F+ L + N P+D Y+C A
Sbjct: 165 PPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVC 224
Query: 2776 DQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVE 2835
+ V+F SP++ I G +T V GG
Sbjct: 225 NIPDKMVSFRLSNKTASPSIKLLVDDPIVVNP--------GEAITLVCVTTGG------- 269
Query: 2836 IRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
P+ + W+R ++ E + + G TL + +T ++G Y+C A + GN
Sbjct: 270 -EPAPS-LTWVRSFGTLPE-----KTVLNGG--TLTIPAITSDDAGTYSCIANNNVGNPA 320
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEP 2941
+ +V+ G+ + KD I +G ++ IS + + P
Sbjct: 321 KKSTNIIVRALK-KGRFWITPDPYHKDDNIQIGREVKISCQVEAVP 365
>AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein protein.
Length = 937
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/205 (32%), Positives = 95/205 (46%), Gaps = 28/205 (13%)
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK---LH 3280
TL I DD G Y A NN G + ++ +RA F +P +K +
Sbjct: 275 TLTIPAITSDDAGTYSCIANNNVGNPAKKSTNII---VRALKKGRFWITPDPYHKDDNIQ 331
Query: 3281 EGDELRISAVVEAYPSVGVT--WYRDGVRLRPSRRAIMT-LDRD---GQIELALAAVTTR 3334
G E++IS VEA PS +T W+++G LR S R ++T D D G L + +
Sbjct: 332 IGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFT 391
Query: 3335 DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE 3394
D G YTC AS + G S ++V S +PP + VP K P+
Sbjct: 392 DFGTYTCVASLKGGGISDIS-IDV----NISSSTVPPNLT---VPQEKSPLV-------- 435
Query: 3395 AREGDTVIIECEVVGDPKPDVYWLR 3419
REGDT+ ++C+V G PKP + W R
Sbjct: 436 TREGDTIELQCQVTGKPKPIILWSR 460
Score = 61.7 bits (143), Expect = 5e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 14/170 (8%)
Query: 2608 GSRVKLTCSV--ISSSDPTVTWYRNGVLLDNKLKYRKKLVD-----GLITLEVLNAVPSD 2660
G VK++C V + S + T +W++NG L + + D G L++++ +D
Sbjct: 333 GREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTD 392
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFT-RSIRDTFHLAENELV-LECRIR 2718
Y+C + G IS ++ + + +S +PP T + E + + L+C++
Sbjct: 393 FGTYTCVASLKGGGIS---DISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVT 449
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
G+P P I W + DK++ DG R+ N + E SG Y C+
Sbjct: 450 GKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIV--NVSREMSGMYRCQ 497
Score = 55.2 bits (127), Expect = 4e-06
Identities = 75/317 (23%), Positives = 122/317 (38%), Gaps = 36/317 (11%)
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L++ N P D A YSC N + + V P+ + D + E
Sbjct: 182 LKLKNLRPQDYANYSCIASVRN--VCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGE 239
Query: 2711 LV-LEC-RIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ L C G+P P +TW + +P + L G L I T +D+GTY+C
Sbjct: 240 AITLVCVTTGGEPAPSLTWVRSFGTLP-----EKTVLNGGT--LTIPAITSDDAGTYSCI 292
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A N+V G ++ S N++ R ++ P + + Q+ R
Sbjct: 293 ANNNV------------GNPAKKSTNII----VRALKKGRFWITPDPYHKDDNIQIGREV 336
Query: 2829 TIGLQVE-IRGCPTRVEWLREGR----SVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
I QVE + W + GR S V V G L + D+ T+ G Y
Sbjct: 337 KISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTY 396
Query: 2884 TCRAWSAHGNV-DMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
TC A G + D++ + + S P + V + + ++ G+ I + + G+PK
Sbjct: 397 TCVASLKGGGISDISIDVNI---SSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPK 453
Query: 2943 PKAVPERIPGEPCVVDG 2959
P + R E + DG
Sbjct: 454 PIILWSRADKEVAMPDG 470
Score = 53.6 bits (123), Expect = 1e-05
Identities = 73/295 (24%), Positives = 113/295 (38%), Gaps = 40/295 (13%)
Query: 3065 GETANLTC-SVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYS 3123
GE L C + G+P P + W+++ + E+ + NG LTI I DD G YS
Sbjct: 238 GEAITLVCVTTGGEPAPSLTWVRSFGTLPEK-----TVLNGGT--LTIPAITSDDAGTYS 290
Query: 3124 CEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATY 3183
C A N G + + +V LK+ R Y +D +Q
Sbjct: 291 CIANNNVGNPAKKSTNIIV---------RALKKGRFWITPDPYH-------KDDNIQIGR 334
Query: 3184 PVRLTCQVIGSPPPKV--SWYKDGEEVVYDKRRNKYQDEQ-----FHTLEIAPTNLDDGG 3236
V+++CQV P ++ SW+K+G + +R Q + L+I D G
Sbjct: 335 EVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFG 394
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGI-RAYVAPEFCCGLE--PLYKLHEGDELRISAVVEA 3293
Y A G +S + +D I + V P E PL EGD + + V
Sbjct: 395 TYTCVASLKGGGIS---DISIDVNISSSTVPPNLTVPQEKSPLV-TREGDTIELQCQVTG 450
Query: 3294 YPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
P + W R + ++ DG L + V+ +G+Y C S G
Sbjct: 451 KPKPIILWSRADKEVAMPDGSMQMESYDG--TLRIVNVSREMSGMYRCQTSQYNG 503
Score = 52.4 bits (120), Expect = 3e-05
Identities = 53/207 (25%), Positives = 90/207 (43%), Gaps = 31/207 (14%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
G+T L C V GKP P ++W + EV G M Q +D L I +++ + G Y C
Sbjct: 439 GDTIELQCQVTGKPKPIILWSRADKEVAMPDGSM--QMESYDGTLRIVNVSREMSGMYRC 496
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
+ + +G + K RE ++ YPP + R
Sbjct: 497 QTSQYNG------------------FNVK-PREALVQLIVQYPPAVEPAFLEIRQGQNRS 537
Query: 3185 VRLTCQVIGSPPPKVSWY--KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
V ++C+V+ + P +V Y + G +++ R ++ +++ + + ++ GVY +
Sbjct: 538 VTMSCRVLRAYPIRVLTYEWRLGNKLL---RTGQFDSQEYTEYAVKSLSNENYGVYNCSI 594
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
N +GA C LV K AY APEF
Sbjct: 595 INEAGAGRCSF-LVTGK---AY-APEF 616
Score = 44.8 bits (101), Expect = 0.006
Identities = 72/307 (23%), Positives = 123/307 (40%), Gaps = 47/307 (15%)
Query: 3062 ILAGETANLTCSVKGKPVPGVV--WMKNGHEVEEEAGRMTSQ----FNGFDCCLTIKDIN 3115
I G ++C V+ P + W KNG + + +Q + L I D+
Sbjct: 330 IQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLK 389
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEV--EGDYPPQFTMR 3173
D G Y+C A+ G S + ++ TV + + +E+S V EGD
Sbjct: 390 FTDFGTYTCVASLKGGGISDISIDVNISSSTV-PPNLTVPQEKSPLVTREGD-------- 440
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLEIAPTNL 3232
+ L CQV G P P + W + +EV Q E + TL I +
Sbjct: 441 ----------TIELQCQVTGKPKPIILWSRADKEVAMPD--GSMQMESYDGTLRIVNVSR 488
Query: 3233 DDGGVYEV-TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY-KLHEGDELRIS-- 3288
+ G+Y T++ N V LV + ++ +EP + ++ +G ++
Sbjct: 489 EMSGMYRCQTSQYNGFNVKPREALV-------QLIVQYPPAVEPAFLEIRQGQNRSVTMS 541
Query: 3289 -AVVEAYPSVGVTW-YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
V+ AYP +T+ +R G +L + + D E A+ +++ + GVY C+ NE
Sbjct: 542 CRVLRAYPIRVLTYEWRLGNKLLRTGQ----FDSQEYTEYAVKSLSNENYGVYNCSIINE 597
Query: 3347 VGRASTS 3353
G S
Sbjct: 598 AGAGRCS 604
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein LRIG1
protein.
Length = 1093
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/252 (26%), Positives = 103/252 (40%), Gaps = 33/252 (13%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L ++ + EGRY C TN G STY+ A +T + P
Sbjct: 562 LHLRQVTFGHEGRYQCVITNHFG--STYSHKARLTVNVL--------------------P 599
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLEI 3227
FT D ++ T RL C G P P+++W KD G + + R + I
Sbjct: 600 SFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFI 659
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+DD GVY TA+N++G++S + L V P LE + G+ + +
Sbjct: 660 TDVKIDDAGVYSCTAQNSAGSISANATLTV------LETPSLVVPLEDRV-VSVGETVAL 712
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
P +TW++ L + R +T D Q+ L + V DAG YTC SN +
Sbjct: 713 QCKATGNPPPRITWFKGDRPLSLTERHHLT--PDNQL-LVVQNVVAEDAGRYTCEMSNTL 769
Query: 3348 GRASTSGKVEVI 3359
G ++ V+
Sbjct: 770 GTERAHSQLSVL 781
Score = 74.1 bits (174), Expect = 8e-12
Identities = 55/201 (27%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK 2637
S S K L+ N P F+ D T + +L C+ +P + W ++G
Sbjct: 585 STYSHKARLTVNVL--PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPA 642
Query: 2638 LKYRKKLVDGLITLEVLNAVPSDSAE-YSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
+ R+ V + + V D A YSCT +N G+IS +A L V + P+
Sbjct: 643 ARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLET-------PSL 695
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
+ D + L+C+ G P P+ITWFK D+ + R+ +L L + N
Sbjct: 696 VVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERH---HLTPDNQLLVVQN 752
Query: 2757 PTPEDSGTYTCKAENSVWTDQ 2777
ED+G YTC+ N++ T++
Sbjct: 753 VVAEDAGRYTCEMSNTLGTER 773
Score = 72.9 bits (171), Expect = 2e-11
Identities = 63/242 (26%), Positives = 88/242 (36%), Gaps = 31/242 (12%)
Query: 3016 GEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVK 3075
G E ++ N +G S + ++ V P F P + I A L C+
Sbjct: 570 GHEGRYQCVITNHFGSTYSHKARLTVNV-----LPSFTKT-PHDITIRTTTVARLECAAT 623
Query: 3076 GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAST 3135
G P P + W K+G A D I D+ IDD G YSC A N+ G S
Sbjct: 624 GHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISA 683
Query: 3136 YARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSP 3195
A L V+ P + L DR V V L C+ G+P
Sbjct: 684 NATLTVLE-----------------------TPSLVVPLEDRVVSVGETVALQCKATGNP 720
Query: 3196 PPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL 3255
PP+++W+K + +R + D Q L + +D G Y N G H L
Sbjct: 721 PPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCEMSNTLGTERAHSQL 778
Query: 3256 VV 3257
V
Sbjct: 779 SV 780
Score = 52.4 bits (120), Expect = 3e-05
Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + L+ G P ++ W ++G + R R+ V
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
++DV ++G+Y+C A ++ G++ NA +TV++ P+++V P +D ++SVGE +
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLE------TPSLVV--PLEDRVVSVGETV 710
Query: 2932 NISFRTQGEPKPK 2944
+ + G P P+
Sbjct: 711 ALQCKATGNPPPR 723
Score = 51.2 bits (117), Expect = 6e-05
Identities = 76/323 (23%), Positives = 121/323 (37%), Gaps = 47/323 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLLDN---KLKYRKKLVDG 2647
KP T A+ G ++ TCS SSS +T W ++ +L N + DG
Sbjct: 494 KPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDG 553
Query: 2648 LI-----TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L + Y C + N G+ S A L V + P+FT++
Sbjct: 554 EVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTV-------NVLPSFTKTPH 606
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
D LEC G P P+I W KD R + ++ I + +D
Sbjct: 607 DITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDD 666
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+G Y+C A+NS +S N LE+ P L D
Sbjct: 667 AGVYSCTAQNSA---------------GSISANATLT--------VLET--PSLVVPLED 701
Query: 2822 YQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V+ G T+ LQ + G P R+ W + R ++ R+ Q L + +V ++
Sbjct: 702 RVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQ---LLVVQNVVAEDA 758
Query: 2881 GLYTCRAWSAHGNVDMNAAITVV 2903
G YTC + G ++ ++V+
Sbjct: 759 GRYTCEMSNTLGTERAHSQLSVL 781
Score = 48.0 bits (109), Expect = 6e-04
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET L C G P P + W K + + N L ++++ +D GR
Sbjct: 704 VSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL---LVVQNVVAEDAGR 760
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y+CE +NT G +++L+V+
Sbjct: 761 YTCEMSNTLGTERAHSQLSVL 781
Score = 46.4 bits (105), Expect = 0.002
Identities = 57/246 (23%), Positives = 90/246 (36%), Gaps = 40/246 (16%)
Query: 3185 VRLTCQVIGSP--PPKVSWYKDGEEVVYDKRRN----KYQD----EQFHTLEIAPTNLDD 3234
+R TC S P +W KD E + N QD E L +
Sbjct: 512 IRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGH 571
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y+ N+ G+ H + V P F + + R+ +
Sbjct: 572 EGRYQCVITNHFGSTYSH-----KARLTVNVLPSFTKTPHDI-TIRTTTVARLECAATGH 625
Query: 3295 PSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
P+ + W +DG P+ R M + D + + V DAGVY+CTA N G S +
Sbjct: 626 PNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQNSAGSISAN 684
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ T P +V VP + + G+TV ++C+ G+P P
Sbjct: 685 ATLTVLET--------PSLV----VPLEDRVVSV----------GETVALQCKATGNPPP 722
Query: 3414 DVYWLR 3419
+ W +
Sbjct: 723 RITWFK 728
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein LIG-1
protein.
Length = 1094
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/252 (26%), Positives = 103/252 (40%), Gaps = 33/252 (13%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L ++ + EGRY C TN G STY+ A +T + P
Sbjct: 562 LHLRQVTFGHEGRYQCVITNHFG--STYSHKARLTVNVL--------------------P 599
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLEI 3227
FT D ++ T RL C G P P+++W KD G + + R + I
Sbjct: 600 SFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFI 659
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+DD GVY TA+N++G++S + L V P LE + G+ + +
Sbjct: 660 TDVKIDDAGVYSCTAQNSAGSISANATLTV------LETPSLVVPLEDRV-VSVGETVAL 712
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
P +TW++ L + R +T D Q+ L + V DAG YTC SN +
Sbjct: 713 QCKATGNPPPRITWFKGDRPLSLTERHHLT--PDNQL-LVVQNVVAEDAGRYTCEMSNTL 769
Query: 3348 GRASTSGKVEVI 3359
G ++ V+
Sbjct: 770 GTERAHSQLSVL 781
Score = 74.9 bits (176), Expect = 5e-12
Identities = 55/201 (27%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Query: 2578 SVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK 2637
S S K L+ N P F+ D T + +L C+ +P + W ++G
Sbjct: 585 STYSHKARLTVNVL--PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPA 642
Query: 2638 LKYRKKLVDGLITLEVLNAVPSDSAE-YSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
+ R+ V + + V D A YSCT +N G+IS +A L V + P+
Sbjct: 643 ARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLET-------PSL 695
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
+ D + L+C+ G P P+ITWFK D+ + R+ +L L + N
Sbjct: 696 VVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERH---HLTPDNQLLVVQN 752
Query: 2757 PTPEDSGTYTCKAENSVWTDQ 2777
ED+G YTC+ N++ T++
Sbjct: 753 VVAEDAGRYTCEMSNTLGTER 773
Score = 72.5 bits (170), Expect = 2e-11
Identities = 63/242 (26%), Positives = 88/242 (36%), Gaps = 31/242 (12%)
Query: 3016 GEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVK 3075
G E ++ N +G S + ++ V P F P + I A L C+
Sbjct: 570 GHEGRYQCVITNHFGSTYSHKARLTVNV-----LPSFTKT-PHDITIRTTTMARLECAAT 623
Query: 3076 GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAST 3135
G P P + W K+G A D I D+ IDD G YSC A N+ G S
Sbjct: 624 GHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSISA 683
Query: 3136 YARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSP 3195
A L V+ P + L DR V V L C+ G+P
Sbjct: 684 NATLTVLE-----------------------TPSLVVPLEDRVVSVGETVALQCKATGNP 720
Query: 3196 PPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL 3255
PP+++W+K + +R + D Q L + +D G Y N G H L
Sbjct: 721 PPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCEMSNTLGTERAHSQL 778
Query: 3256 VV 3257
V
Sbjct: 779 SV 780
Score = 52.0 bits (119), Expect = 4e-05
Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + L+ G P ++ W ++G + R R+ V
Sbjct: 599 PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
++DV ++G+Y+C A ++ G++ NA +TV++ P+++V P +D ++SVGE +
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLE------TPSLVV--PLEDRVVSVGETV 710
Query: 2932 NISFRTQGEPKPK 2944
+ + G P P+
Sbjct: 711 ALQCKATGNPPPR 723
Score = 51.2 bits (117), Expect = 6e-05
Identities = 76/323 (23%), Positives = 121/323 (37%), Gaps = 47/323 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLLDN---KLKYRKKLVDG 2647
KP T A+ G ++ TCS SSS +T W ++ +L N + DG
Sbjct: 494 KPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDG 553
Query: 2648 LI-----TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIR 2701
+ L + Y C + N G+ S A L V + P+FT++
Sbjct: 554 EVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTV-------NVLPSFTKTPH 606
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPED 2761
D LEC G P P+I W KD R + ++ I + +D
Sbjct: 607 DITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDD 666
Query: 2762 SGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTD 2821
+G Y+C A+NS +S N LE+ P L D
Sbjct: 667 AGVYSCTAQNSA---------------GSISANATLT--------VLET--PSLVVPLED 701
Query: 2822 YQVARGGTIGLQVEIRG-CPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V+ G T+ LQ + G P R+ W + R ++ R+ Q L + +V ++
Sbjct: 702 RVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQ---LLVVQNVVAEDA 758
Query: 2881 GLYTCRAWSAHGNVDMNAAITVV 2903
G YTC + G ++ ++V+
Sbjct: 759 GRYTCEMSNTLGTERAHSQLSVL 781
Score = 48.0 bits (109), Expect = 6e-04
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET L C G P P + W K + + N L ++++ +D GR
Sbjct: 704 VSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL---LVVQNVVAEDAGR 760
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y+CE +NT G +++L+V+
Sbjct: 761 YTCEMSNTLGTERAHSQLSVL 781
Score = 46.4 bits (105), Expect = 0.002
Identities = 57/246 (23%), Positives = 90/246 (36%), Gaps = 40/246 (16%)
Query: 3185 VRLTCQVIGSP--PPKVSWYKDGEEVVYDKRRN----KYQD----EQFHTLEIAPTNLDD 3234
+R TC S P +W KD E + N QD E L +
Sbjct: 512 IRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGH 571
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y+ N+ G+ H + V P F + + R+ +
Sbjct: 572 EGRYQCVITNHFGSTYSH-----KARLTVNVLPSFTKTPHDI-TIRTTTMARLECAATGH 625
Query: 3295 PSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
P+ + W +DG P+ R M + D + + V DAGVY+CTA N G S +
Sbjct: 626 PNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQNSAGSISAN 684
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ V+ T P +V VP + + G+TV ++C+ G+P P
Sbjct: 685 ATLTVLET--------PSLV----VPLEDRVVSV----------GETVALQCKATGNPPP 722
Query: 3414 DVYWLR 3419
+ W +
Sbjct: 723 RITWFK 728
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 79.8 bits (188), Expect = 2e-13
Identities = 100/397 (25%), Positives = 163/397 (41%), Gaps = 67/397 (16%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHE 3090
GE+ ++S+ V L D +F P + + AGE A L C +G P P + W K+
Sbjct: 117 GEAVSRNASLEVALLRD--DFRQN-PTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVR 173
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
++++ R++ + L I + D G Y+C TN G+ R + + TV+E
Sbjct: 174 IDDKEERISIRGGK----LMISNTRKSDAGMYTCVGTNMVGE-----RDSDPAELTVFER 224
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
P F R ++ V V CQV G P P V W KD
Sbjct: 225 -----------------PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDA---- 263
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
D R +Y + +TL I T D G Y A N G + L V RA P+F
Sbjct: 264 DLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV----RA--PPQFV 317
Query: 3271 CGLEPLYKL-HEGDELRISAVVEAYPSVGVTWYRDGVR--LRPSR----RAIMTLDRDGQ 3323
+ P ++ +G + + P V W ++G + L P++ + ++ G
Sbjct: 318 --VRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG- 374
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
+L + + DAG Y C A G ++EV TD ++ R PP+++
Sbjct: 375 -DLTITNIQRSDAGYYICQALTVAGSILAKAQLEV--TDVLTD-RPPPIIL--------- 421
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ P + T +++C+ GDP P + WL++
Sbjct: 422 ----QGPANQTLAVDGTALLKCKATGDPLPVISWLKE 454
Score = 73.7 bits (173), Expect = 1e-11
Identities = 72/264 (27%), Positives = 104/264 (39%), Gaps = 38/264 (14%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-----RRNKYQD 3219
D+PP+ D V P L C+ G P P + WYKDGE V DK R
Sbjct: 28 DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 87
Query: 3220 EQFHTLEI--APTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D G Y ARN G AVS + L V A + +F +
Sbjct: 88 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV-----ALLRDDFRQNPTDV 142
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ +P + W +D VR+ I R G +L ++ DA
Sbjct: 143 VVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI--RGG--KLMISNTRKSDA 198
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+YTC +N VG ++ S+P ++ + P F+R+P +
Sbjct: 199 GMYTCVGTNMVG-------------ERDSDP--------AELTVFERPTFLRRPINQVVL 237
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
E + V C+V GDP+P V W +D
Sbjct: 238 EEEAVEFRCQVQGDPQPTVRWKKD 261
Score = 73.7 bits (173), Expect = 1e-11
Identities = 81/322 (25%), Positives = 126/322 (39%), Gaps = 38/322 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP F+ Q+ +L E C V+G P P V W K+ ++ GR + D
Sbjct: 223 ERPTFLRRPINQV-VLEEEAVEFRCQVQGDPQPTVRWKKDDADLPR--GRYDIKD---DY 276
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L IK DEG Y C A N GK E SA + P
Sbjct: 277 TLRIKKTMSTDEGTYMCIAENRVGKM-----------------------EASATLTVRAP 313
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH---T 3224
PQF +R RD+ V V C+ G+P P V W K+G + + + + + + T
Sbjct: 314 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 373
Query: 3225 LEIAPTNL--DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
++ TN+ D G Y A +G++ L V + P G +G
Sbjct: 374 GDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDG 433
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
L + P ++W ++G P R T+ G +++ ++ D G YTC
Sbjct: 434 TAL-LKCKATGDPLPVISWLKEGFTF-PGRDPRATIQEQGTLQIKNLRIS--DTGTYTCV 489
Query: 3343 ASNEVGRASTSGKVEVIGTDQT 3364
A++ G S S ++V + T
Sbjct: 490 ATSSSGETSWSAVLDVTESGAT 511
Score = 72.9 bits (171), Expect = 2e-11
Identities = 91/353 (25%), Positives = 147/353 (41%), Gaps = 57/353 (16%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL----DNKLKYRKKLVDG-LITLEVLN 2655
+D +G L C PT+ WY++G + D+ +R L G L L +++
Sbjct: 38 SDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVH 97
Query: 2656 AVPS--DSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
S D Y C N G A+S +A+L E + + F ++ D A +
Sbjct: 98 GRRSKPDEGSYVCVARNYLGEAVSRNASL------EVALLRDDFRQNPTDVVVAAGEPAI 151
Query: 2713 LECR-IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC+ RG P P I W KD +I D + + + G +L I N D+G YTC N
Sbjct: 152 LECQPPRGHPEPTIYWKKDKVRI--DDKEERISIRGG--KLMISNTRKSDAGMYTCVGTN 207
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V R+S AE T R + RRP V+ + + +
Sbjct: 208 MVGE-----------RDSD------PAELTVFERPTF-LRRP-INQVVLEEE-----AVE 243
Query: 2832 LQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ +++G P V W ++ + R ++ YTL + T+ G Y C A +
Sbjct: 244 FRCQVQGDPQPTVRWKKDDADLP----RGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENR 298
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ +A +TV P P +V RP +D +++ G + T+G P+P
Sbjct: 299 VGKMEASATLTVRAP------PQFVV-RP-RDQIVAQGRTVTFPCETKGNPQP 343
Score = 69.7 bits (163), Expect = 2e-10
Identities = 93/351 (26%), Positives = 138/351 (39%), Gaps = 51/351 (14%)
Query: 2601 TDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
TD G L C +PT+ W ++ V +D+K + R + G L + N S
Sbjct: 140 TDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDK-EERISIRGG--KLMISNTRKS 196
Query: 2660 DSAEYSCTVENENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D+ Y+C N G S A L V+ PTF R + L E + C+++
Sbjct: 197 DAGMYTCVGTNMVGERDSDPAELTVFER-------PTFLRRPINQVVLEEEAVEFRCQVQ 249
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
G P P + W KDD +P GRY + D L I D GTY C AEN V
Sbjct: 250 GDPQPTVRWKKDDADLPR-GRYD---IKDDY-TLRIKKTMSTDEGTYMCIAENRV----- 299
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
G+ + A T R P F D VA+G T+ E +G
Sbjct: 300 -------GK--------MEASATLTVRAP-----PQFVVRPRDQIVAQGRTVTFPCETKG 339
Query: 2839 CP-TRVEWLREGRS-----VTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
P V W +EG N+R V L ++++ +++G Y C+A + G
Sbjct: 340 NPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP-TGDLTITNIQRSDAGYYICQALTVAG 398
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ A + V D P +I+ P L G + + + G+P P
Sbjct: 399 SILAKAQLEVTDVL-TDRPPPIILQGPANQTLAVDGTAL-LKCKATGDPLP 447
Score = 67.3 bits (157), Expect = 9e-10
Identities = 91/372 (24%), Positives = 131/372 (35%), Gaps = 66/372 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE-----AGRMTSQFNG-FDCCLT 3110
P + + GE L C +G+P P + W K+G VE + + RM F +
Sbjct: 37 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIV 96
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ DEG Y C A N G+A + R S EV F
Sbjct: 97 HGRRSKPDEGSYVCVARNYLGEA--------------------VSRNASLEV-ALLRDDF 135
Query: 3171 TMRLRDRRVQATYPVRLTCQ-VIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D V A P L CQ G P P + W KD + + R + + L I+
Sbjct: 136 RQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK---LMISN 192
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRIS 3288
T D G+Y N G + + P F P+ + + E + +
Sbjct: 193 TRKSDAGMYTCVGTNMVGERDSD-----PAELTVFERPTFL--RRPINQVVLEEEAVEFR 245
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
V+ P V W +D L R D L + + D G Y C A N VG
Sbjct: 246 CQVQGDPQPTVRWKKDDADLPRGR-----YDIKDDYTLRIKKTMSTDEGTYMCIAENRVG 300
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVV 3408
+ S + V R P P F+ +PR +G TV CE
Sbjct: 301 KMEASATLTV---------RAP-------------PQFVVRPRDQIVAQGRTVTFPCETK 338
Query: 3409 GDPKPDVYWLRD 3420
G+P+P V+W ++
Sbjct: 339 GNPQPAVFWQKE 350
Score = 67.3 bits (157), Expect = 9e-10
Identities = 90/382 (23%), Positives = 143/382 (37%), Gaps = 43/382 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F ++ +E V+ C V PTV W ++ L + R + D TL
Sbjct: 224 RPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP---RGRYDIKDDY-TLR 279
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + +D Y C EN G + SA L V PP F RD +
Sbjct: 280 IKKTMSTDEGTYMCIAENRVGKMEASATLTVRA-------PPQFVVRPRDQIVAQGRTVT 332
Query: 2713 LECRIRGQPLPKITWFKDDKQ---IPSDGRY-QAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
C +G P P + W K+ Q P+ + + L I N D+G Y C+
Sbjct: 333 FPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQ 392
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A +T + + +V+T I Q P + +A G
Sbjct: 393 A--------LTVAGSILAKAQLEVTDVLTDRPPPIILQG-----P------ANQTLAVDG 433
Query: 2829 TIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTETESGLYTCR 2886
T L+ + G P V WL+EG T R+ R + EQG TL + ++ +++G YTC
Sbjct: 434 TALLKCKATGDPLPVISWLKEG--FTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCV 489
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
A S+ G +A + V + K + P V + S +P
Sbjct: 490 ATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQP---GT 546
Query: 2947 PERIPGEPCVVDGGNNWVSLAW 2968
P +P +++ + VS +W
Sbjct: 547 PGTLPASAYIIEAFSQSVSNSW 568
Score = 43.2 bits (97), Expect = 0.017
Identities = 61/260 (23%), Positives = 103/260 (39%), Gaps = 44/260 (16%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS---DGRYQAFYLADG- 2748
PP D L C+ G+P P I W+KD +++ + D R L G
Sbjct: 30 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 89
Query: 2749 --VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
R+ + D G+Y C A N+ G VS N A
Sbjct: 90 LFFLRIVHGRRSKPDEGSYVCVAR------------NYLG--EAVSRN---------ASL 126
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVE-IRGCP-TRVEWLREGRSVTEVYRNARVFVE 2864
+ R F TD VA G L+ + RG P + W ++ + + + R+ +
Sbjct: 127 EVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDD--KEERISIR 184
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMN-AAITVVQPSDLDGKPAVIVGRPEKDI 2923
G L +S+ ++++G+YTC + G D + A +TV + +P + RP +
Sbjct: 185 GG--KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFE------RP-TFLRRPINQV 235
Query: 2924 LISVGEDINISFRTQGEPKP 2943
++ E + + QG+P+P
Sbjct: 236 VLE-EEAVEFRCQVQGDPQP 254
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 79.8 bits (188), Expect = 2e-13
Identities = 100/397 (25%), Positives = 163/397 (41%), Gaps = 67/397 (16%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHE 3090
GE+ ++S+ V L D +F P + + AGE A L C +G P P + W K+
Sbjct: 133 GEAVSRNASLEVALLRD--DFRQN-PTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVR 189
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
++++ R++ + L I + D G Y+C TN G+ R + + TV+E
Sbjct: 190 IDDKEERISIRGGK----LMISNTRKSDAGMYTCVGTNMVGE-----RDSDPAELTVFER 240
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
P F R ++ V V CQV G P P V W KD
Sbjct: 241 -----------------PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDA---- 279
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
D R +Y + +TL I T D G Y A N G + L V RA P+F
Sbjct: 280 DLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV----RA--PPQFV 333
Query: 3271 CGLEPLYKL-HEGDELRISAVVEAYPSVGVTWYRDGVR--LRPSR----RAIMTLDRDGQ 3323
+ P ++ +G + + P V W ++G + L P++ + ++ G
Sbjct: 334 --VRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG- 390
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
+L + + DAG Y C A G ++EV TD ++ R PP+++
Sbjct: 391 -DLTITNIQRSDAGYYICQALTVAGSILAKAQLEV--TDVLTD-RPPPIIL--------- 437
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ P + T +++C+ GDP P + WL++
Sbjct: 438 ----QGPANQTLAVDGTALLKCKATGDPLPVISWLKE 470
Score = 73.7 bits (173), Expect = 1e-11
Identities = 72/264 (27%), Positives = 104/264 (39%), Gaps = 38/264 (14%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-----RRNKYQD 3219
D+PP+ D V P L C+ G P P + WYKDGE V DK R
Sbjct: 44 DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 103
Query: 3220 EQFHTLEI--APTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D G Y ARN G AVS + L V A + +F +
Sbjct: 104 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV-----ALLRDDFRQNPTDV 158
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ +P + W +D VR+ I R G +L ++ DA
Sbjct: 159 VVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI--RGG--KLMISNTRKSDA 214
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+YTC +N VG ++ S+P ++ + P F+R+P +
Sbjct: 215 GMYTCVGTNMVG-------------ERDSDP--------AELTVFERPTFLRRPINQVVL 253
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
E + V C+V GDP+P V W +D
Sbjct: 254 EEEAVEFRCQVQGDPQPTVRWKKD 277
Score = 73.7 bits (173), Expect = 1e-11
Identities = 81/322 (25%), Positives = 126/322 (39%), Gaps = 38/322 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP F+ Q+ +L E C V+G P P V W K+ ++ GR + D
Sbjct: 239 ERPTFLRRPINQV-VLEEEAVEFRCQVQGDPQPTVRWKKDDADLPR--GRYDIKD---DY 292
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L IK DEG Y C A N GK E SA + P
Sbjct: 293 TLRIKKTMSTDEGTYMCIAENRVGKM-----------------------EASATLTVRAP 329
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH---T 3224
PQF +R RD+ V V C+ G+P P V W K+G + + + + + + T
Sbjct: 330 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 389
Query: 3225 LEIAPTNL--DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
++ TN+ D G Y A +G++ L V + P G +G
Sbjct: 390 GDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDG 449
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
L + P ++W ++G P R T+ G +++ ++ D G YTC
Sbjct: 450 TAL-LKCKATGDPLPVISWLKEGFTF-PGRDPRATIQEQGTLQIKNLRIS--DTGTYTCV 505
Query: 3343 ASNEVGRASTSGKVEVIGTDQT 3364
A++ G S S ++V + T
Sbjct: 506 ATSSSGETSWSAVLDVTESGAT 527
Score = 72.9 bits (171), Expect = 2e-11
Identities = 91/353 (25%), Positives = 147/353 (41%), Gaps = 57/353 (16%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL----DNKLKYRKKLVDG-LITLEVLN 2655
+D +G L C PT+ WY++G + D+ +R L G L L +++
Sbjct: 54 SDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVH 113
Query: 2656 AVPS--DSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
S D Y C N G A+S +A+L E + + F ++ D A +
Sbjct: 114 GRRSKPDEGSYVCVARNYLGEAVSRNASL------EVALLRDDFRQNPTDVVVAAGEPAI 167
Query: 2713 LECR-IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC+ RG P P I W KD +I D + + + G +L I N D+G YTC N
Sbjct: 168 LECQPPRGHPEPTIYWKKDKVRI--DDKEERISIRGG--KLMISNTRKSDAGMYTCVGTN 223
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V R+S AE T R + RRP V+ + + +
Sbjct: 224 MVGE-----------RDSD------PAELTVFERPTF-LRRP-INQVVLEEE-----AVE 259
Query: 2832 LQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ +++G P V W ++ + R ++ YTL + T+ G Y C A +
Sbjct: 260 FRCQVQGDPQPTVRWKKDDADLP----RGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENR 314
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ +A +TV P P +V RP +D +++ G + T+G P+P
Sbjct: 315 VGKMEASATLTVRAP------PQFVV-RP-RDQIVAQGRTVTFPCETKGNPQP 359
Score = 69.7 bits (163), Expect = 2e-10
Identities = 93/351 (26%), Positives = 138/351 (39%), Gaps = 51/351 (14%)
Query: 2601 TDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
TD G L C +PT+ W ++ V +D+K + R + G L + N S
Sbjct: 156 TDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDK-EERISIRGG--KLMISNTRKS 212
Query: 2660 DSAEYSCTVENENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D+ Y+C N G S A L V+ PTF R + L E + C+++
Sbjct: 213 DAGMYTCVGTNMVGERDSDPAELTVFER-------PTFLRRPINQVVLEEEAVEFRCQVQ 265
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
G P P + W KDD +P GRY + D L I D GTY C AEN V
Sbjct: 266 GDPQPTVRWKKDDADLPR-GRYD---IKDDY-TLRIKKTMSTDEGTYMCIAENRV----- 315
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
G+ + A T R P F D VA+G T+ E +G
Sbjct: 316 -------GK--------MEASATLTVRAP-----PQFVVRPRDQIVAQGRTVTFPCETKG 355
Query: 2839 CP-TRVEWLREGRS-----VTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
P V W +EG N+R V L ++++ +++G Y C+A + G
Sbjct: 356 NPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP-TGDLTITNIQRSDAGYYICQALTVAG 414
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ A + V D P +I+ P L G + + + G+P P
Sbjct: 415 SILAKAQLEVTDVL-TDRPPPIILQGPANQTLAVDGTAL-LKCKATGDPLP 463
Score = 67.3 bits (157), Expect = 9e-10
Identities = 91/372 (24%), Positives = 131/372 (35%), Gaps = 66/372 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE-----AGRMTSQFNG-FDCCLT 3110
P + + GE L C +G+P P + W K+G VE + + RM F +
Sbjct: 53 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIV 112
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ DEG Y C A N G+A + R S EV F
Sbjct: 113 HGRRSKPDEGSYVCVARNYLGEA--------------------VSRNASLEV-ALLRDDF 151
Query: 3171 TMRLRDRRVQATYPVRLTCQ-VIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D V A P L CQ G P P + W KD + + R + + L I+
Sbjct: 152 RQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK---LMISN 208
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRIS 3288
T D G+Y N G + + P F P+ + + E + +
Sbjct: 209 TRKSDAGMYTCVGTNMVGERDSD-----PAELTVFERPTFL--RRPINQVVLEEEAVEFR 261
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
V+ P V W +D L R D L + + D G Y C A N VG
Sbjct: 262 CQVQGDPQPTVRWKKDDADLPRGR-----YDIKDDYTLRIKKTMSTDEGTYMCIAENRVG 316
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVV 3408
+ S + V R P P F+ +PR +G TV CE
Sbjct: 317 KMEASATLTV---------RAP-------------PQFVVRPRDQIVAQGRTVTFPCETK 354
Query: 3409 GDPKPDVYWLRD 3420
G+P+P V+W ++
Sbjct: 355 GNPQPAVFWQKE 366
Score = 67.3 bits (157), Expect = 9e-10
Identities = 90/382 (23%), Positives = 143/382 (37%), Gaps = 43/382 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F ++ +E V+ C V PTV W ++ L + R + D TL
Sbjct: 240 RPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP---RGRYDIKDDY-TLR 295
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + +D Y C EN G + SA L V PP F RD +
Sbjct: 296 IKKTMSTDEGTYMCIAENRVGKMEASATLTVRA-------PPQFVVRPRDQIVAQGRTVT 348
Query: 2713 LECRIRGQPLPKITWFKDDKQ---IPSDGRY-QAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
C +G P P + W K+ Q P+ + + L I N D+G Y C+
Sbjct: 349 FPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQ 408
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A +T + + +V+T I Q P + +A G
Sbjct: 409 A--------LTVAGSILAKAQLEVTDVLTDRPPPIILQG-----P------ANQTLAVDG 449
Query: 2829 TIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTETESGLYTCR 2886
T L+ + G P V WL+EG T R+ R + EQG TL + ++ +++G YTC
Sbjct: 450 TALLKCKATGDPLPVISWLKEG--FTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCV 505
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
A S+ G +A + V + K + P V + S +P
Sbjct: 506 ATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQP---GT 562
Query: 2947 PERIPGEPCVVDGGNNWVSLAW 2968
P +P +++ + VS +W
Sbjct: 563 PGTLPASAYIIEAFSQSVSNSW 584
Score = 43.2 bits (97), Expect = 0.017
Identities = 61/260 (23%), Positives = 103/260 (39%), Gaps = 44/260 (16%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS---DGRYQAFYLADG- 2748
PP D L C+ G+P P I W+KD +++ + D R L G
Sbjct: 46 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 105
Query: 2749 --VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
R+ + D G+Y C A N+ G VS N A
Sbjct: 106 LFFLRIVHGRRSKPDEGSYVCVAR------------NYLG--EAVSRN---------ASL 142
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVE-IRGCP-TRVEWLREGRSVTEVYRNARVFVE 2864
+ R F TD VA G L+ + RG P + W ++ + + + R+ +
Sbjct: 143 EVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDD--KEERISIR 200
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMN-AAITVVQPSDLDGKPAVIVGRPEKDI 2923
G L +S+ ++++G+YTC + G D + A +TV + +P + RP +
Sbjct: 201 GG--KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFE------RP-TFLRRPINQV 251
Query: 2924 LISVGEDINISFRTQGEPKP 2943
++ E + + QG+P+P
Sbjct: 252 VLE-EEAVEFRCQVQGDPQP 270
>BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein.
Length = 637
Score = 79.8 bits (188), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 77.4 bits (182), Expect = 9e-13
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 66.1 bits (154), Expect = 2e-09
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G PT V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 58.0 bits (134), Expect = 6e-07
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 44.8 bits (101), Expect = 0.006
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
>BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein.
Length = 558
Score = 79.8 bits (188), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 77.4 bits (182), Expect = 9e-13
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 66.1 bits (154), Expect = 2e-09
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G PT V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 58.0 bits (134), Expect = 6e-07
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 44.8 bits (101), Expect = 0.006
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
>BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein.
Length = 305
Score = 79.8 bits (188), Expect = 2e-13
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 21/197 (10%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEA-GRMTSQFNGFDCCLTIKDINIDDEG 3120
+L G TA + G PVP V W ++G + + F+ LTI + + G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 3121 RYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
RYS +ATN G+A++ A L V K E + PP F RL+ V+
Sbjct: 77 RYSLKATNGSGQATSTAELLV-------------KAETA-------PPNFVQRLQSMTVR 116
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
VRL +V G P P V +Y+DG E+ Q+ ++L IA +D G Y V
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 3241 TARNNSGAVSCHCGLVV 3257
A N+ G + L+V
Sbjct: 177 NATNSVGRATSTAELLV 193
Score = 77.4 bits (182), Expect = 9e-13
Identities = 57/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 2590 STRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK--YRKKLVDG 2647
+T+ P F+ L +EGS + P V+W+R+G ++ + DG
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + ++S YS N +G +++A L V +A PP F + ++
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSMTVRQ 117
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+++ L+ R+ G P P + +++D +I S +Q D + L I PEDSGTY+
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSV 176
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
A NSV T + G E + T T +S ++R
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 72.1 bits (169), Expect = 3e-11
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 13/227 (5%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN---KYQDEQFHT 3224
P FT L+ V + G P P+VSW++DG+ + + D +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK- 64
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAP-EFCCGLEPLYKLHEGD 3283
L I + G Y + A N SG + L+V +A AP F L+ + + +G
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV----KAETAPPNFVQRLQSM-TVRQGS 119
Query: 3284 ELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYTCT 3342
++R+ V P+ V +YRDG ++ S + ++G + L +A D+G Y+
Sbjct: 120 QVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVN 177
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
A+N VGRA+++ ++ V G ++ + +V + + S++ +K
Sbjct: 178 ATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKK 224
Score = 66.1 bits (154), Expect = 2e-09
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA-FYLADGVCRL 2752
PTFT+ ++ L + E I G P+P+++WF+D + I + +DG +L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 2753 AIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRR 2812
I T +SG Y+ KA N +G+ + + +V AE +
Sbjct: 66 TIPAVTKANSGRYSLKATNG------------SGQATSTAELLVKAE----------TAP 103
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P+F L V +G + LQV + G PT V++ R+G + + + ++ E LY+L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLL 162
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+++ +SG Y+ A ++ G A + V ++ K
Sbjct: 163 IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Score = 58.0 bits (134), Expect = 6e-07
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
Query: 2567 RHRSKAFSEARSVISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT 2626
R+ KA + + S L + T P F L T +GS+V+L V P V
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 2627 WYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
+YR+G + + L ++ L +L + A P DS YS N G +++A L V
Sbjct: 137 FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 2687 FEASPIPPTFTRSIRDTFHLAEN 2709
E +P T++I T ++E+
Sbjct: 197 EE---VPAKKTKTIVSTAQISES 216
Score = 44.8 bits (101), Expect = 0.006
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 3030 GWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGH 3089
G G+++ T+ + V P FV L + + G L V G P P V + ++G
Sbjct: 85 GSGQATSTAELL-VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 3090 EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
E++ SQ G L I + +D G YS ATN+ G+A++ A L V + V
Sbjct: 143 EIQSSLDFQISQ-EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B protein.
Length = 1960
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 5 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 64
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 65 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 117
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 118 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 177
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 178 NRLGSARASAELRI 191
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 4 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 63
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 64 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 116
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 117 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 176
Query: 2770 EN 2771
N
Sbjct: 177 VN 178
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 20 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 79
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 80 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 116
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 117 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 176
Query: 3243 RNNSGA 3248
N G+
Sbjct: 177 VNRLGS 182
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 20 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 79
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 80 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 117
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 118 QFTCTIEGAPYPQIRWYKD 136
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 5 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 63
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 64 LILDSLTGVDSGQYMCFAASA 84
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYT 3340
G + A++E P VTWY+D V+L S R ++ ++G L L V ++DAGVYT
Sbjct: 363 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVASKDAGVYT 420
Query: 3341 CTASNEVGRASTSGKVEVIGTD 3362
C A N G+ ++ V+G D
Sbjct: 421 CLAQNTGGQVLCKAELLVLGGD 442
Score = 55.2 bits (127), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP + + D + Q + + G P P V+WYKD ++V R ++ Q+ ++L
Sbjct: 348 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 407
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ D GVY A+N G V C L+V
Sbjct: 408 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438
Score = 53.6 bits (123), Expect = 1e-05
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 12/130 (9%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G + ++ V A P+ TW +DG L S R +++ L + V D GVYTC
Sbjct: 1469 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 1528
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV--PYSKEPMFIRKPRSSEAREGD 3399
+ SN +G +T+G + + P P PD+ Y+ + + KP E+
Sbjct: 1529 SVSNALGTVTTTGVLR-----KAERPSSSP---CPDIGEVYADGVLLVWKP--VESYGPV 1578
Query: 3400 TVIIECEVVG 3409
T I++C + G
Sbjct: 1579 TYIVQCSLEG 1588
Score = 51.2 bits (117), Expect = 6e-05
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLIT 2650
R P F L+D T V G V L C V + TW ++G L++ + +
Sbjct: 1453 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 1512
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L +L V D Y+C+V N G ++T+ L+ +SP P
Sbjct: 1513 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 1555
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 112 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 171
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 172 YECELVNRLGSARASAELRI 191
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 4 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 63
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 64 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 115
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 116 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 154
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RP + + ++ G TA ++G P P V W K+ ++ + R++ Q G
Sbjct: 347 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDST-RLSQQQEGTTYS 405
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L ++ + D G Y+C A NT G+ A L V+
Sbjct: 406 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 439
Score = 48.0 bits (109), Expect = 6e-04
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 3/123 (2%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
PTF R + D + + L C++ QP + TW KD + S R L
Sbjct: 1455 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 1514
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR-ESQVSPNV--VTAEKTRIARQSLES 2810
I ED G YTC N++ T T + R S P++ V A+ + + +ES
Sbjct: 1515 ILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVES 1574
Query: 2811 RRP 2813
P
Sbjct: 1575 YGP 1577
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 89 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 147
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 148 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 191
Score = 43.2 bits (97), Expect = 0.017
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP+ +I D E I G P P +TW+KD Q+ R L
Sbjct: 348 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQ-QQEGTTYSL 406
Query: 2753 AIDNPTPEDSGTYTCKAENS 2772
+ + +D+G YTC A+N+
Sbjct: 407 VLRHVASKDAGVYTCLAQNT 426
Score = 42.7 bits (96), Expect = 0.022
Identities = 21/100 (21%), Positives = 42/100 (42%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKK 2643
+ + ++ R P + D A G + + P+VTWY++ V L + + ++
Sbjct: 339 QAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ 398
Query: 2644 LVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+L + + D+ Y+C +N G + A L V
Sbjct: 399 QEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438
Score = 40.7 bits (91), Expect = 0.090
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
+R P + D Q GGT + I G P V W ++ + + R ++ E Y
Sbjct: 346 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ-QEGTTY 404
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L L V ++G+YTC A + G V A + V+
Sbjct: 405 SLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 439
Score = 40.7 bits (91), Expect = 0.090
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L + +L G++ L C V +P W K+G +E + + S L
Sbjct: 1455 PTFLRELSDETVVL-GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 1513
Query: 3110 TIKDINIDDEGRYSCEATNTHGKAST 3135
TI + +D G Y+C +N G +T
Sbjct: 1514 TILVVVAEDLGVYTCSVSNALGTVTT 1539
Score = 39.9 bits (89), Expect = 0.16
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNKYQDEQFH 3223
D P F L D V V L CQV P + +W KDG + R + F
Sbjct: 1452 DRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQ 1511
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVS 3250
L I +D GVY + N G V+
Sbjct: 1512 LLTILVVVAEDLGVYTCSVSNALGTVT 1538
Score = 35.1 bits (77), Expect = 4.5
Identities = 16/48 (33%), Positives = 24/48 (50%)
Query: 3379 PYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 1 PVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 48
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 741
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 742 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 801
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 802 NRLGSARASAELRI 815
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 628 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 740
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 741 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 800
Query: 2770 EN 2771
N
Sbjct: 801 VN 802
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 704 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 740
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 741 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 800
Query: 3243 RNNSGA 3248
N G+
Sbjct: 801 VNRLGS 806
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 704 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 741
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 742 QFTCTIEGAPYPQIRWYKD 760
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 629 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 688 LILDSLTGVDSGQYMCFAASA 708
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYT 3340
G + A++E P VTWY+D V+L S R ++ ++G L L V ++DAGVYT
Sbjct: 987 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVASKDAGVYT 1044
Query: 3341 CTASNEVGRASTSGKVEVIGTD 3362
C A N G+ ++ V+G D
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGD 1066
Score = 55.2 bits (127), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP + + D + Q + + G P P V+WYKD ++V R ++ Q+ ++L
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ D GVY A+N G V C L+V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062
Score = 53.6 bits (123), Expect = 1e-05
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 12/130 (9%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G + ++ V A P+ TW +DG L S R +++ L + V D GVYTC
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV--PYSKEPMFIRKPRSSEAREGD 3399
+ SN +G +T+G + + P P PD+ Y+ + + KP E+
Sbjct: 2153 SVSNALGTVTTTGVLR-----KAERPSSSP---CPDIGEVYADGVLLVWKP--VESYGPV 2202
Query: 3400 TVIIECEVVG 3409
T I++C + G
Sbjct: 2203 TYIVQCSLEG 2212
Score = 51.2 bits (117), Expect = 6e-05
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLIT 2650
R P F L+D T V G V L C V + TW ++G L++ + +
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L +L V D Y+C+V N G ++T+ L+ +SP P
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 2179
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 736 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 795
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 796 YECELVNRLGSARASAELRI 815
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 628 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 739
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 740 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 778
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RP + + ++ G TA ++G P P V W K+ ++ + R++ Q G
Sbjct: 971 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDST-RLSQQQEGTTYS 1029
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L ++ + D G Y+C A NT G+ A L V+
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 48.0 bits (109), Expect = 6e-04
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 3/123 (2%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
PTF R + D + + L C++ QP + TW KD + S R L
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR-ESQVSPNV--VTAEKTRIARQSLES 2810
I ED G YTC N++ T T + R S P++ V A+ + + +ES
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVES 2198
Query: 2811 RRP 2813
P
Sbjct: 2199 YGP 2201
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 713 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 771
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 772 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815
Score = 43.2 bits (97), Expect = 0.017
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP+ +I D E I G P P +TW+KD Q+ R L
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQ-QQEGTTYSL 1030
Query: 2753 AIDNPTPEDSGTYTCKAENS 2772
+ + +D+G YTC A+N+
Sbjct: 1031 VLRHVASKDAGVYTCLAQNT 1050
Score = 42.7 bits (96), Expect = 0.022
Identities = 21/100 (21%), Positives = 42/100 (42%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKK 2643
+ + ++ R P + D A G + + P+VTWY++ V L + + ++
Sbjct: 963 QAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ 1022
Query: 2644 LVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+L + + D+ Y+C +N G + A L V
Sbjct: 1023 QEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062
Score = 40.7 bits (91), Expect = 0.090
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
+R P + D Q GGT + I G P V W ++ + + R ++ E Y
Sbjct: 970 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ-QEGTTY 1028
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L L V ++G+YTC A + G V A + V+
Sbjct: 1029 SLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 40.7 bits (91), Expect = 0.090
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L + +L G++ L C V +P W K+G +E + + S L
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137
Query: 3110 TIKDINIDDEGRYSCEATNTHGKAST 3135
TI + +D G Y+C +N G +T
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALGTVTT 2163
Score = 39.9 bits (89), Expect = 0.16
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNKYQDEQFH 3223
D P F L D V V L CQV P + +W KDG + R + F
Sbjct: 2076 DRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVS 3250
L I +D GVY + N G V+
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVT 2162
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 624 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 672
Score = 35.1 bits (77), Expect = 4.5
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 5/87 (5%)
Query: 3285 LRISAVVEAYPSVGVTWYRD----GVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
+ S VE P V W R+ GV + P Q L L V + G Y
Sbjct: 3 ITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTY 62
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSE 3366
TC ASN G+A S + V G + E
Sbjct: 63 TCIASNAAGQALCSASLHVSGLPKVEE 89
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 741
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 742 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 801
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 802 NRLGSARASAELRI 815
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 628 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 740
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 741 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 800
Query: 2770 EN 2771
N
Sbjct: 801 VN 802
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 704 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 740
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 741 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 800
Query: 3243 RNNSGA 3248
N G+
Sbjct: 801 VNRLGS 806
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 704 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 741
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 742 QFTCTIEGAPYPQIRWYKD 760
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 629 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 688 LILDSLTGVDSGQYMCFAASA 708
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYT 3340
G + A++E P VTWY+D V+L S R ++ ++G L L V ++DAGVYT
Sbjct: 987 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVASKDAGVYT 1044
Query: 3341 CTASNEVGRASTSGKVEVIGTD 3362
C A N G+ ++ V+G D
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGD 1066
Score = 55.2 bits (127), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP + + D + Q + + G P P V+WYKD ++V R ++ Q+ ++L
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ D GVY A+N G V C L+V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062
Score = 53.6 bits (123), Expect = 1e-05
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 12/130 (9%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G + ++ V A P+ TW +DG L S R +++ L + V D GVYTC
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV--PYSKEPMFIRKPRSSEAREGD 3399
+ SN +G +T+G + + P P PD+ Y+ + + KP E+
Sbjct: 2153 SVSNALGTVTTTGVLR-----KAERPSSSP---CPDIGEVYADGVLLVWKP--VESYGPV 2202
Query: 3400 TVIIECEVVG 3409
T I++C + G
Sbjct: 2203 TYIVQCSLEG 2212
Score = 51.2 bits (117), Expect = 6e-05
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLIT 2650
R P F L+D T V G V L C V + TW ++G L++ + +
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L +L V D Y+C+V N G ++T+ L+ +SP P
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 2179
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 736 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 795
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 796 YECELVNRLGSARASAELRI 815
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 628 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 739
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 740 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 778
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RP + + ++ G TA ++G P P V W K+ ++ + R++ Q G
Sbjct: 971 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDST-RLSQQQEGTTYS 1029
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L ++ + D G Y+C A NT G+ A L V+
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 48.0 bits (109), Expect = 6e-04
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 3/123 (2%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
PTF R + D + + L C++ QP + TW KD + S R L
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR-ESQVSPNV--VTAEKTRIARQSLES 2810
I ED G YTC N++ T T + R S P++ V A+ + + +ES
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVES 2198
Query: 2811 RRP 2813
P
Sbjct: 2199 YGP 2201
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 713 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 771
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 772 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815
Score = 43.2 bits (97), Expect = 0.017
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP+ +I D E I G P P +TW+KD Q+ R L
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQ-QQEGTTYSL 1030
Query: 2753 AIDNPTPEDSGTYTCKAENS 2772
+ + +D+G YTC A+N+
Sbjct: 1031 VLRHVASKDAGVYTCLAQNT 1050
Score = 42.7 bits (96), Expect = 0.022
Identities = 21/100 (21%), Positives = 42/100 (42%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKK 2643
+ + ++ R P + D A G + + P+VTWY++ V L + + ++
Sbjct: 963 QAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ 1022
Query: 2644 LVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+L + + D+ Y+C +N G + A L V
Sbjct: 1023 QEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062
Score = 40.7 bits (91), Expect = 0.090
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
+R P + D Q GGT + I G P V W ++ + + R ++ E Y
Sbjct: 970 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ-QEGTTY 1028
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L L V ++G+YTC A + G V A + V+
Sbjct: 1029 SLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 40.7 bits (91), Expect = 0.090
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L + +L G++ L C V +P W K+G +E + + S L
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137
Query: 3110 TIKDINIDDEGRYSCEATNTHGKAST 3135
TI + +D G Y+C +N G +T
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALGTVTT 2163
Score = 39.9 bits (89), Expect = 0.16
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNKYQDEQFH 3223
D P F L D V V L CQV P + +W KDG + R + F
Sbjct: 2076 DRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVS 3250
L I +D GVY + N G V+
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVT 2162
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 624 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 672
Score = 35.1 bits (77), Expect = 4.5
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 5/87 (5%)
Query: 3285 LRISAVVEAYPSVGVTWYRD----GVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
+ S VE P V W R+ GV + P Q L L V + G Y
Sbjct: 3 ITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTY 62
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSE 3366
TC ASN G+A S + V G + E
Sbjct: 63 TCIASNAAGQALCSASLHVSGLPKVEE 89
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 413 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 472
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 473 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 525
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 526 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 585
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 586 NRLGSARASAELRI 599
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 412 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 471
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 472 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 524
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 525 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 584
Query: 2770 EN 2771
N
Sbjct: 585 VN 586
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 428 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 487
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 488 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 524
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 525 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 584
Query: 3243 RNNSGA 3248
N G+
Sbjct: 585 VNRLGS 590
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 428 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 487
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 488 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 525
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 526 QFTCTIEGAPYPQIRWYKD 544
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 413 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 471
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 472 LILDSLTGVDSGQYMCFAASA 492
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 520 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 579
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 580 YECELVNRLGSARASAELRI 599
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 412 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 471
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 472 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 523
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 524 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 562
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 497 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 555
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 556 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 599
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 408 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 456
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 79.8 bits (188), Expect = 2e-13
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP F L D + V+L C+V G+P P +SWYKDG+ V D +D
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 3227 IAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I + D G Y A + +G S ++V V P F + EG++
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ------VPPRFVNKVR-ASPFVEGEDA 741
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRR-AIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + +E P + WY+DG L + ++ R G + L + A + D G+Y C
Sbjct: 742 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 801
Query: 3345 NEVGRASTSGKVEV 3358
N +G A S ++ +
Sbjct: 802 NRLGSARASAELRI 815
Score = 77.4 bits (182), Expect = 9e-13
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 9/182 (4%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLIT 2650
R P F L D TA G VKL C V + P ++WY++G + + + DG
Sbjct: 628 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
L + + DS +Y C + G ST + V +PP F +R + + +
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV-------QVPPRFVNKVRASPFVEGED 740
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAF-YLADGVCRLAIDNPTPEDSGTYTCKA 2769
C I G P P+I W+KD + + ++Q G+ L I + ED G Y C+
Sbjct: 741 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 800
Query: 2770 EN 2771
N
Sbjct: 801 VN 802
Score = 65.3 bits (152), Expect = 4e-09
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GET L C V G P P + W K+G V+ + + + C L + + D G+Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A + G ST ++ V PP+F ++R
Sbjct: 704 FAASAAGNCSTLGKILV-----------------------QVPPRFVNKVRASPFVEGED 740
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ--FHTLEIAPTNLDDGGVYEVTA 3242
+ TC + G+P P++ WYKDG + + + + L I + +D G+YE
Sbjct: 741 AQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECEL 800
Query: 3243 RNNSGA 3248
N G+
Sbjct: 801 VNRLGS 806
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G+ ++++ V P ++WY+DG ++ I+ D DG L L ++T D+G Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G ST GK+ V ++P P F+ K R+S EG+
Sbjct: 704 FAASAAGNCSTLGKILV---------QVP-------------PRFVNKVRASPFVEGEDA 741
Query: 3402 IIECEVVGDPKPDVYWLRD 3420
C + G P P + W +D
Sbjct: 742 QFTCTIEGAPYPQIRWYKD 760
Score = 58.8 bits (136), Expect = 3e-07
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 2693 PPTFTRSIRD-TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + D T L E + L CR+ G P P I+W+KD K + D + DG C
Sbjct: 629 PPDFEEELADCTAELGET-VKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
L +D+ T DSG Y C A ++
Sbjct: 688 LILDSLTGVDSGQYMCFAASA 708
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYT 3340
G + A++E P VTWY+D V+L S R ++ ++G L L V ++DAGVYT
Sbjct: 987 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVASKDAGVYT 1044
Query: 3341 CTASNEVGRASTSGKVEVIGTD 3362
C A N G+ ++ V+G D
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGD 1066
Score = 55.2 bits (127), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
PP + + D + Q + + G P P V+WYKD ++V R ++ Q+ ++L
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ D GVY A+N G V C L+V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062
Score = 53.6 bits (123), Expect = 1e-05
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 12/130 (9%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G + ++ V A P+ TW +DG L S R +++ L + V D GVYTC
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDV--PYSKEPMFIRKPRSSEAREGD 3399
+ SN +G +T+G + + P P PD+ Y+ + + KP E+
Sbjct: 2153 SVSNALGTVTTTGVLR-----KAERPSSSP---CPDIGEVYADGVLLVWKP--VESYGPV 2202
Query: 3400 TVIIECEVVG 3409
T I++C + G
Sbjct: 2203 TYIVQCSLEG 2212
Score = 51.2 bits (117), Expect = 6e-05
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR-KKLVDGLIT 2650
R P F L+D T V G V L C V + TW ++G L++ + +
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136
Query: 2651 LEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP 2693
L +L V D Y+C+V N G ++T+ L+ +SP P
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 2179
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLD--NKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
VEG + TC++ + P + WY++G LL NK + + GL+ L + A D
Sbjct: 736 VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGL 795
Query: 2664 YSCTVENENGAISTSANLKV 2683
Y C + N G+ SA L++
Sbjct: 796 YECELVNRLGSARASAELRI 815
Score = 48.0 bits (109), Expect = 6e-04
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 2811 RRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYT 2869
R P F L D G T+ L + G P V W ++G++V + + G
Sbjct: 628 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687
Query: 2870 LALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGE 2929
L L +T +SG Y C A SA GN I V P K + P + GE
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNK---VRASPFVE-----GE 739
Query: 2930 DINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
D + +G P P+ R + ++ GN + +L+ P+S
Sbjct: 740 DAQFTCTIEGAPYPQI---RWYKDGALLTTGNKFQTLSEPRS 778
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
RP + + ++ G TA ++G P P V W K+ ++ + R++ Q G
Sbjct: 971 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDST-RLSQQQEGTTYS 1029
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L ++ + D G Y+C A NT G+ A L V+
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 48.0 bits (109), Expect = 6e-04
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 3/123 (2%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
PTF R + D + + L C++ QP + TW KD + S R L
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138
Query: 2754 IDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR-ESQVSPNV--VTAEKTRIARQSLES 2810
I ED G YTC N++ T T + R S P++ V A+ + + +ES
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVES 2198
Query: 2811 RRP 2813
P
Sbjct: 2199 YGP 2201
Score = 45.2 bits (102), Expect = 0.004
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 3039 SSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRM 3098
S++G L P FV+ + + GE A TC+++G P P + W K+G +
Sbjct: 713 STLGKILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 771
Query: 3099 T-SQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
T S+ L I+ + +D G Y CE N G A A L +
Sbjct: 772 TLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815
Score = 43.2 bits (97), Expect = 0.017
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRL 2752
PP+ +I D E I G P P +TW+KD Q+ R L
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQ-QQEGTTYSL 1030
Query: 2753 AIDNPTPEDSGTYTCKAENS 2772
+ + +D+G YTC A+N+
Sbjct: 1031 VLRHVASKDAGVYTCLAQNT 1050
Score = 42.7 bits (96), Expect = 0.022
Identities = 21/100 (21%), Positives = 42/100 (42%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKK 2643
+ + ++ R P + D A G + + P+VTWY++ V L + + ++
Sbjct: 963 QAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ 1022
Query: 2644 LVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+L + + D+ Y+C +N G + A L V
Sbjct: 1023 QEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062
Score = 40.7 bits (91), Expect = 0.090
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
+R P + D Q GGT + I G P V W ++ + + R ++ E Y
Sbjct: 970 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ-QEGTTY 1028
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L L V ++G+YTC A + G V A + V+
Sbjct: 1029 SLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 40.7 bits (91), Expect = 0.090
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F+ L + +L G++ L C V +P W K+G +E + + S L
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137
Query: 3110 TIKDINIDDEGRYSCEATNTHGKAST 3135
TI + +D G Y+C +N G +T
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALGTVTT 2163
Score = 39.9 bits (89), Expect = 0.16
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNKYQDEQFH 3223
D P F L D V V L CQV P + +W KDG + R + F
Sbjct: 2076 DRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVS 3250
L I +D GVY + N G V+
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVT 2162
Score = 35.5 bits (78), Expect = 3.4
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 3378 VPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVRI 3426
+P + P F + A G+TV + C V G PKP + W +D V++
Sbjct: 624 LPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV 672
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 79.8 bits (188), Expect = 2e-13
Identities = 100/397 (25%), Positives = 163/397 (41%), Gaps = 67/397 (16%)
Query: 3032 GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSV-KGKPVPGVVWMKNGHE 3090
GE+ ++S+ V L D +F P + + AGE A L C +G P P + W K+
Sbjct: 119 GEAVSRNASLEVALLRD--DFRQN-PTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVR 175
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
++++ R++ + L I + D G Y+C TN G+ R + + TV+E
Sbjct: 176 IDDKEERISIRGGK----LMISNTRKSDAGMYTCVGTNMVGE-----RDSDPAELTVFER 226
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
P F R ++ V V CQV G P P V W KD
Sbjct: 227 -----------------PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDA---- 265
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFC 3270
D R +Y + +TL I T D G Y A N G + L V RA P+F
Sbjct: 266 DLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV----RA--PPQFV 319
Query: 3271 CGLEPLYKL-HEGDELRISAVVEAYPSVGVTWYRDGVR--LRPSR----RAIMTLDRDGQ 3323
+ P ++ +G + + P V W ++G + L P++ + ++ G
Sbjct: 320 --VRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG- 376
Query: 3324 IELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKE 3383
+L + + DAG Y C A G ++EV TD ++ R PP+++
Sbjct: 377 -DLTITNIQRSDAGYYICQALTVAGSILAKAQLEV--TDVLTD-RPPPIIL--------- 423
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+ P + T +++C+ GDP P + WL++
Sbjct: 424 ----QGPANQTLAVDGTALLKCKATGDPLPVISWLKE 456
Score = 73.7 bits (173), Expect = 1e-11
Identities = 72/264 (27%), Positives = 104/264 (39%), Gaps = 38/264 (14%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-----RRNKYQD 3219
D+PP+ D V P L C+ G P P + WYKDGE V DK R
Sbjct: 30 DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 89
Query: 3220 EQFHTLEI--APTNLDDGGVYEVTARNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPL 3276
L I + D G Y ARN G AVS + L V A + +F +
Sbjct: 90 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV-----ALLRDDFRQNPTDV 144
Query: 3277 YKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA 3336
+ +P + W +D VR+ I R G +L ++ DA
Sbjct: 145 VVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI--RGG--KLMISNTRKSDA 200
Query: 3337 GVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR 3396
G+YTC +N VG ++ S+P ++ + P F+R+P +
Sbjct: 201 GMYTCVGTNMVG-------------ERDSDP--------AELTVFERPTFLRRPINQVVL 239
Query: 3397 EGDTVIIECEVVGDPKPDVYWLRD 3420
E + V C+V GDP+P V W +D
Sbjct: 240 EEEAVEFRCQVQGDPQPTVRWKKD 263
Score = 73.7 bits (173), Expect = 1e-11
Identities = 81/322 (25%), Positives = 126/322 (39%), Gaps = 38/322 (11%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
+RP F+ Q+ +L E C V+G P P V W K+ ++ GR + D
Sbjct: 225 ERPTFLRRPINQV-VLEEEAVEFRCQVQGDPQPTVRWKKDDADLPR--GRYDIKD---DY 278
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L IK DEG Y C A N GK E SA + P
Sbjct: 279 TLRIKKTMSTDEGTYMCIAENRVGKM-----------------------EASATLTVRAP 315
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH---T 3224
PQF +R RD+ V V C+ G+P P V W K+G + + + + + + T
Sbjct: 316 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 375
Query: 3225 LEIAPTNL--DDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
++ TN+ D G Y A +G++ L V + P G +G
Sbjct: 376 GDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDG 435
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCT 3342
L + P ++W ++G P R T+ G +++ ++ D G YTC
Sbjct: 436 TAL-LKCKATGDPLPVISWLKEGFTF-PGRDPRATIQEQGTLQIKNLRIS--DTGTYTCV 491
Query: 3343 ASNEVGRASTSGKVEVIGTDQT 3364
A++ G S S ++V + T
Sbjct: 492 ATSSSGETSWSAVLDVTESGAT 513
Score = 72.9 bits (171), Expect = 2e-11
Identities = 91/353 (25%), Positives = 147/353 (41%), Gaps = 57/353 (16%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLL----DNKLKYRKKLVDG-LITLEVLN 2655
+D +G L C PT+ WY++G + D+ +R L G L L +++
Sbjct: 40 SDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVH 99
Query: 2656 AVPS--DSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
S D Y C N G A+S +A+L E + + F ++ D A +
Sbjct: 100 GRRSKPDEGSYVCVARNYLGEAVSRNASL------EVALLRDDFRQNPTDVVVAAGEPAI 153
Query: 2713 LECR-IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
LEC+ RG P P I W KD +I D + + + G +L I N D+G YTC N
Sbjct: 154 LECQPPRGHPEPTIYWKKDKVRI--DDKEERISIRGG--KLMISNTRKSDAGMYTCVGTN 209
Query: 2772 SVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIG 2831
V R+S AE T R + RRP V+ + + +
Sbjct: 210 MVGE-----------RDSD------PAELTVFERPTF-LRRP-INQVVLEEE-----AVE 245
Query: 2832 LQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
+ +++G P V W ++ + R ++ YTL + T+ G Y C A +
Sbjct: 246 FRCQVQGDPQPTVRWKKDDADLP----RGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENR 300
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
G ++ +A +TV P P +V RP +D +++ G + T+G P+P
Sbjct: 301 VGKMEASATLTVRAP------PQFVV-RP-RDQIVAQGRTVTFPCETKGNPQP 345
Score = 69.7 bits (163), Expect = 2e-10
Identities = 93/351 (26%), Positives = 138/351 (39%), Gaps = 51/351 (14%)
Query: 2601 TDRTAVEGSRVKLTCSVISSS-DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
TD G L C +PT+ W ++ V +D+K + R + G L + N S
Sbjct: 142 TDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDK-EERISIRGG--KLMISNTRKS 198
Query: 2660 DSAEYSCTVENENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
D+ Y+C N G S A L V+ PTF R + L E + C+++
Sbjct: 199 DAGMYTCVGTNMVGERDSDPAELTVFER-------PTFLRRPINQVVLEEEAVEFRCQVQ 251
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
G P P + W KDD +P GRY + D L I D GTY C AEN V
Sbjct: 252 GDPQPTVRWKKDDADLPR-GRYD---IKDDY-TLRIKKTMSTDEGTYMCIAENRV----- 301
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
G+ + A T R P F D VA+G T+ E +G
Sbjct: 302 -------GK--------MEASATLTVRAP-----PQFVVRPRDQIVAQGRTVTFPCETKG 341
Query: 2839 CP-TRVEWLREGRS-----VTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
P V W +EG N+R V L ++++ +++G Y C+A + G
Sbjct: 342 NPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP-TGDLTITNIQRSDAGYYICQALTVAG 400
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
++ A + V D P +I+ P L G + + + G+P P
Sbjct: 401 SILAKAQLEVTDVL-TDRPPPIILQGPANQTLAVDGTAL-LKCKATGDPLP 449
Score = 67.3 bits (157), Expect = 9e-10
Identities = 91/372 (24%), Positives = 131/372 (35%), Gaps = 66/372 (17%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE-----AGRMTSQFNG-FDCCLT 3110
P + + GE L C +G+P P + W K+G VE + + RM F +
Sbjct: 39 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIV 98
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF 3170
+ DEG Y C A N G+A + R S EV F
Sbjct: 99 HGRRSKPDEGSYVCVARNYLGEA--------------------VSRNASLEV-ALLRDDF 137
Query: 3171 TMRLRDRRVQATYPVRLTCQ-VIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
D V A P L CQ G P P + W KD + + R + + L I+
Sbjct: 138 RQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK---LMISN 194
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK-LHEGDELRIS 3288
T D G+Y N G + + P F P+ + + E + +
Sbjct: 195 TRKSDAGMYTCVGTNMVGERDSD-----PAELTVFERPTFL--RRPINQVVLEEEAVEFR 247
Query: 3289 AVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
V+ P V W +D L R D L + + D G Y C A N VG
Sbjct: 248 CQVQGDPQPTVRWKKDDADLPRGR-----YDIKDDYTLRIKKTMSTDEGTYMCIAENRVG 302
Query: 3349 RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVV 3408
+ S + V R P P F+ +PR +G TV CE
Sbjct: 303 KMEASATLTV---------RAP-------------PQFVVRPRDQIVAQGRTVTFPCETK 340
Query: 3409 GDPKPDVYWLRD 3420
G+P+P V+W ++
Sbjct: 341 GNPQPAVFWQKE 352
Score = 67.3 bits (157), Expect = 9e-10
Identities = 90/382 (23%), Positives = 143/382 (37%), Gaps = 43/382 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F ++ +E V+ C V PTV W ++ L + R + D TL
Sbjct: 226 RPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP---RGRYDIKDDY-TLR 281
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + +D Y C EN G + SA L V PP F RD +
Sbjct: 282 IKKTMSTDEGTYMCIAENRVGKMEASATLTVRA-------PPQFVVRPRDQIVAQGRTVT 334
Query: 2713 LECRIRGQPLPKITWFKDDKQ---IPSDGRY-QAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
C +G P P + W K+ Q P+ + + L I N D+G Y C+
Sbjct: 335 FPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQ 394
Query: 2769 AENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
A +T + + +V+T I Q P + +A G
Sbjct: 395 A--------LTVAGSILAKAQLEVTDVLTDRPPPIILQG-----P------ANQTLAVDG 435
Query: 2829 TIGLQVEIRGCPTRV-EWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTETESGLYTCR 2886
T L+ + G P V WL+EG T R+ R + EQG TL + ++ +++G YTC
Sbjct: 436 TALLKCKATGDPLPVISWLKEG--FTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCV 491
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
A S+ G +A + V + K + P V + S +P
Sbjct: 492 ATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQP---GT 548
Query: 2947 PERIPGEPCVVDGGNNWVSLAW 2968
P +P +++ + VS +W
Sbjct: 549 PGTLPASAYIIEAFSQSVSNSW 570
Score = 43.2 bits (97), Expect = 0.017
Identities = 61/260 (23%), Positives = 103/260 (39%), Gaps = 44/260 (16%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPS---DGRYQAFYLADG- 2748
PP D L C+ G+P P I W+KD +++ + D R L G
Sbjct: 32 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 91
Query: 2749 --VCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
R+ + D G+Y C A N+ G VS N A
Sbjct: 92 LFFLRIVHGRRSKPDEGSYVCVAR------------NYLG--EAVSRN---------ASL 128
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVE-IRGCP-TRVEWLREGRSVTEVYRNARVFVE 2864
+ R F TD VA G L+ + RG P + W ++ + + + R+ +
Sbjct: 129 EVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDD--KEERISIR 186
Query: 2865 QGLYTLALSDVTETESGLYTCRAWSAHGNVDMN-AAITVVQPSDLDGKPAVIVGRPEKDI 2923
G L +S+ ++++G+YTC + G D + A +TV + +P + RP +
Sbjct: 187 GG--KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFE------RP-TFLRRPINQV 237
Query: 2924 LISVGEDINISFRTQGEPKP 2943
++ E + + QG+P+P
Sbjct: 238 VLE-EEAVEFRCQVQGDPQP 256
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 79.0 bits (186), Expect = 3e-13
Identities = 81/313 (25%), Positives = 129/313 (41%), Gaps = 35/313 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLD-NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVE 2669
V + C P++TWY++ +++ KL ++ DG L++ VP D+ + C
Sbjct: 3 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGLVPDDTGMFQCFAR 60
Query: 2670 NENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFK 2729
N G + TS L V + I P TR D+ + +VL C G P P ITW K
Sbjct: 61 NAAGEVQTSTYLAV------TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK 114
Query: 2730 DDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRES 2789
++ + S + L I D+GTYTC A NS D
Sbjct: 115 GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD------------- 161
Query: 2790 QVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREG 2849
+ S ++V +TRI ++ P +V+ Q + G+ + R R W ++G
Sbjct: 162 EASADLVVWARTRI------TKPPQDQSVIKGTQASM--VCGVTHDPR-VTIRYIWEKDG 212
Query: 2850 RSV-TEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDL 2908
++ TE + R+ L+ +S + G YTCR SA GN +A + V Q
Sbjct: 213 ATLGTESHPRIRLDRNGSLH---ISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHA 269
Query: 2909 DGKPAVIVGRPEK 2921
P + E+
Sbjct: 270 PEHPVATLSTVER 282
Score = 75.8 bits (178), Expect = 3e-12
Identities = 77/297 (25%), Positives = 115/297 (38%), Gaps = 38/297 (12%)
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCE 3125
+ ++ C KG P P + W K+ VE E Q N D L I + DD G + C
Sbjct: 1 KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN--DGGLQISGLVPDDTGMFQCF 58
Query: 3126 ATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPV 3185
A N G+ T LAV + P T D V V
Sbjct: 59 ARNAAGEVQTSTYLAVTS----------------------IAPNITRGPLDSTVIDGMSV 96
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVY--DKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+ G+P P ++W K GE ++ + ++ + +L I+PT++ D G Y A
Sbjct: 97 VLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLAT 155
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV--TW 3301
N+ G LVV R P+ + +G + + V P V + W
Sbjct: 156 NSRGVDEASADLVVWARTRITKPPQD-------QSVIKGTQASMVCGVTHDPRVTIRYIW 208
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
+DG L + LDR+G L ++ + D G YTC + G S S + V
Sbjct: 209 EKDGATLGTESHPRIRLDRNG--SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 263
Score = 64.1 bits (149), Expect = 8e-09
Identities = 53/187 (28%), Positives = 85/187 (45%), Gaps = 15/187 (8%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
V + CQ G PPP ++WYKD VV ++ +++ L+I+ DD G+++ ARN
Sbjct: 3 VDIPCQAKGVPPPSITWYKDA-AVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARN 61
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPSVGVTWYR 3303
+G V L V +AP G PL + +G + ++ P +TW +
Sbjct: 62 AAGEVQTSTYLAVTS-----IAPNITRG--PLDSTVIDGMSVVLACETSGAPRPAITWQK 114
Query: 3304 DGVRLRPSRRAIMTLDRDGQIE---LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
G R+ S + L R +E L ++ DAG YTC A+N G S + V
Sbjct: 115 -GERILAS--GSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 171
Query: 3361 TDQTSEP 3367
+ ++P
Sbjct: 172 RTRITKP 178
Score = 44.0 bits (99), Expect = 0.010
Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 22/189 (11%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDN---KLKYR 2641
+++ N TR P+ D T ++G V L C + P +TW + +L + +L
Sbjct: 76 SIAPNITRGPL------DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRF 129
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
L G + + + SD+ Y+C N G SA+L V+ + PP I+
Sbjct: 130 TPLESGSLLISPTHI--SDAGTYTCLATNSRGVDEASADLVVWARTRITK-PPQDQSVIK 186
Query: 2702 DTFHLAENELVLECRIRGQPLPKI--TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
T + + C + P I W KD + ++ + +G L I
Sbjct: 187 GT------QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG--SLHISQTWS 238
Query: 2760 EDSGTYTCK 2768
D GTYTC+
Sbjct: 239 GDIGTYTCR 247
Score = 42.7 bits (96), Expect = 0.022
Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC-CLTIKDINIDDEG 3120
++ G + L C G P P + W K G + +F + L I +I D G
Sbjct: 90 VIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAG 148
Query: 3121 RYSCEATNTHGKASTYARLAV 3141
Y+C ATN+ G A L V
Sbjct: 149 TYTCLATNSRGVDEASADLVV 169
Score = 37.9 bits (84), Expect = 0.64
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 10/106 (9%)
Query: 2939 GEPKPKAVPER----IPGEPCVV---DGGNNWVSLAW-PKSDPQTTAPVLAYKVESWLIG 2990
G P + ER +PG P + + V L W P + P +LAY++ L
Sbjct: 962 GSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI--ILAYQITHRLNT 1019
Query: 2991 AEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQ 3036
VE+ + A LK Y FR+T + R GWGE+++
Sbjct: 1020 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAE 1065
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 78.6 bits (185), Expect = 4e-13
Identities = 86/331 (25%), Positives = 122/331 (36%), Gaps = 42/331 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 343 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 400
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 401 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 438
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 439 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 496
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 497 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 549
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 550 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 604
Query: 3354 GKVEVIGTDQTSEPRIPPVVIS-PDVPYSKE 3383
+ V+ T R+ + PD P E
Sbjct: 605 AYLTVLADQATPTNRLAALPKGRPDRPRDLE 635
Score = 59.7 bits (138), Expect = 2e-07
Identities = 83/320 (25%), Positives = 124/320 (38%), Gaps = 46/320 (14%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 351 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 409
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 410 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 464 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 509
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 510 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 555
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 556 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 610
Query: 2904 --QPSDLDGKPAVIVGRPEK 2921
Q + + A+ GRP++
Sbjct: 611 ADQATPTNRLAALPKGRPDR 630
Score = 50.0 bits (114), Expect = 1e-04
Identities = 85/356 (23%), Positives = 139/356 (39%), Gaps = 50/356 (14%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 118
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 119 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 171
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A
Sbjct: 172 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNAR----------- 216
Query: 2782 VNFTGRESQVSPNVVTAEKTR-IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+FT Q +P + TR +A ++ P + V RG + L+ G P
Sbjct: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ--GTASSQMVLRGMDLLLECIASGVP 274
Query: 2841 TR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W ++G + + + E L +++V+E +SG Y C A + G++ +
Sbjct: 275 TPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
Query: 2900 ITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
+ V P LD +P K+++++ GED + R G PKP V + GEP
Sbjct: 331 VRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGEP 376
Score = 48.8 bits (111), Expect = 3e-04
Identities = 87/363 (23%), Positives = 139/363 (38%), Gaps = 57/363 (15%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 211
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
SC A T+T + + + L V+T R V E +G Q +R D
Sbjct: 212 SCNARFHFTHTIQQKNPFT-LKVLTTRGVAERTPSFMYP-----QGTASSQMVLRGMD-- 263
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ L C G P P ++WYK G ++ DK K+++ L I + +D G Y
Sbjct: 264 ------LLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEEDSGEY 314
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N G++ H +R AP + + L L G++ R+ P
Sbjct: 315 FCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGNPKPT 367
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTSGKVE 3357
V W +G P + A +R+ + + T VY C SNE G + V
Sbjct: 368 VQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 424
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ +PP ++SP IR + R ++C G P P + W
Sbjct: 425 VLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIPTLRW 464
Query: 3418 LRD 3420
++
Sbjct: 465 FKN 467
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 258 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 313
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 314 YFCLASNKMG 323
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 254 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 310
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 311 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 363
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 364 PKPTVQWMVNGEPLQS 379
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 78.6 bits (185), Expect = 4e-13
Identities = 83/302 (27%), Positives = 127/302 (42%), Gaps = 29/302 (9%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+ PV +T L A+ C+V S P ++W RN +L+ R + + L
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILI-KLFDTRYSIRENGQLL 84
Query: 2652 EVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+L+ SD Y CT N GA+ + L+V + P TR + + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV-------KMKPKITRPPINVKIIEGLK 137
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
VL C G P P ++W K D + + R L G L I N ED+G Y C A+
Sbjct: 138 AVLPCTTMGNPKPSVSWIKGDSPLRENSRIAV--LESG--SLRIHNVQKEDAGQYRCVAK 193
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS+ T + V E + P T RI R + ES FG+ +T + A G +
Sbjct: 194 NSLGT-AYSKVVKLE-VEEESEPEQDTKVFARILR-APESHNVTFGSFVTLHCTATGIPV 250
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
PT + W+ G +V+ + + V+ + L + T+ GLYTC A +
Sbjct: 251 ---------PT-ITWIENGNAVSS--GSIQESVKDRVIDSRL-QLFITKPGLYTCIATNK 297
Query: 2891 HG 2892
HG
Sbjct: 298 HG 299
Score = 62.1 bits (144), Expect = 3e-08
Identities = 60/233 (25%), Positives = 95/233 (40%), Gaps = 24/233 (10%)
Query: 3189 CQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C V P P++SW ++ + ++D R + ++ Q T+ ++ + DDG +Y TA N G
Sbjct: 49 CAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTI-LSVEDSDDG-IYCCTANNGVG 106
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
CG + K P K+ EG + + P V+W +
Sbjct: 107 GAVESCGALQVKMKPKITRPPINV------KIIEGLKAVLPCTTMGNPKPSVSWIKGDSP 160
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
LR + R I L+ L + V DAG Y C A N +G A + KV + ++ SEP
Sbjct: 161 LRENSR-IAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYS--KVVKLEVEEESEP 214
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
V + +R P S G V + C G P P + W+ +
Sbjct: 215 EQDTKVFA---------RILRAPESHNVTFGSFVTLHCTATGIPVPTITWIEN 258
Score = 53.2 bits (122), Expect = 2e-05
Identities = 72/297 (24%), Positives = 118/297 (39%), Gaps = 34/297 (11%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L E A C+V+ P P + W +N ++ R + + NG LTI + D+G Y
Sbjct: 40 LVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQ--LLTILSVEDSDDGIY 97
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A N G A V + K K R P +++ + ++A
Sbjct: 98 CCTANNGVGGA--------VESCGALQVKMKPKITR---------PPINVKIIEG-LKAV 139
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
P C +G+P P VSW K G+ + + R + +L I +D G Y A
Sbjct: 140 LP----CTTMGNPKPSVSWIK-GDSPLRENSRIAVLES--GSLRIHNVQKEDAGQYRCVA 192
Query: 3243 RNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE---GDELRISAVVEAYPSVG 3298
+N+ G A S L V++ + + + H G + + P
Sbjct: 193 KNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVTLHCTATGIPVPT 252
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+TW +G + S +I +D I+ L T+ G+YTC A+N+ G ++ K
Sbjct: 253 ITWIENGNAV--SSGSIQESVKDRVIDSRLQLFITK-PGLYTCIATNKHGEKFSTAK 306
Score = 51.2 bits (117), Expect = 6e-05
Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 26/195 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +KI+ G A L C+ G P P V W+K + E + R+ +G L I ++
Sbjct: 127 PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS-RIAVLESG---SLRIHNVQK 182
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR- 3175
+D G+Y C A N+ G A Y+++ KL+ E +E E D F LR
Sbjct: 183 EDAGQYRCVAKNSLGTA--YSKV------------VKLEVEEESEPEQD-TKVFARILRA 227
Query: 3176 --DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNL 3232
V V L C G P P ++W ++G V + +D + L++ T
Sbjct: 228 PESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITK- 286
Query: 3233 DDGGVYEVTARNNSG 3247
G+Y A N G
Sbjct: 287 --PGLYTCIATNKHG 299
Score = 50.4 bits (115), Expect = 1e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 24/154 (15%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP LE + L E + VE+YP ++W R+ + ++ ++ +GQ+
Sbjct: 27 APVITTPLETVDALVE-EVATFMCAVESYPQPEISWTRNKILIKLFDTRY-SIRENGQL- 83
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +V D G+Y CTA+N VG G VE G Q +P
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVG-----GAVESCGALQV----------------KMKPK 122
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
R P + + EG ++ C +G+PKP V W++
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIK 156
Score = 48.0 bits (109), Expect = 6e-04
Identities = 39/167 (23%), Positives = 64/167 (38%), Gaps = 7/167 (4%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW+ G + + S N+++ + +R +N G S +
Sbjct: 153 SWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEEES 212
Query: 3046 AG--DRPEFVDIL--PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQ 3101
D F IL P + G L C+ G PVP + W++NG+ V + + + +
Sbjct: 213 EPEQDTKVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVK 272
Query: 3102 FNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVW 3148
D L + I G Y+C ATN HG+ + A+ A W
Sbjct: 273 DRVIDSRL---QLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEW 316
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGR 2739
L + E P P T + L E C + P P+I+W ++ I D R
Sbjct: 15 LVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR 74
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
Y + + L I + D G Y C A N V
Sbjct: 75 YS---IRENGQLLTILSVEDSDDGIYCCTANNGV 105
>BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein.
Length = 347
Score = 78.6 bits (185), Expect = 4e-13
Identities = 62/233 (26%), Positives = 102/233 (43%), Gaps = 23/233 (9%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 188
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVV---DKGIRAYVAPEFC 3270
L+I + D G YE A N++G S L V D G ++P+ C
Sbjct: 189 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSC 241
Score = 74.1 bits (174), Expect = 8e-12
Identities = 53/187 (28%), Positives = 77/187 (41%), Gaps = 7/187 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 208
Query: 2769 AENSVWT 2775
A NS T
Sbjct: 209 ATNSAGT 215
Score = 58.4 bits (135), Expect = 4e-07
Identities = 59/239 (24%), Positives = 96/239 (40%), Gaps = 12/239 (5%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 200
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
D G Y C A+N G R S + V G D S + P + S + + R R
Sbjct: 201 -DQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSPWCRHAR 258
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 42.3 bits (95), Expect = 0.030
Identities = 59/203 (29%), Positives = 90/203 (44%), Gaps = 27/203 (13%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 191
Query: 3109 LTIKDINIDDEGRYSCEATNTHG 3131
L I+ D+G+Y C ATN+ G
Sbjct: 192 LQIESSEESDQGKYECVATNSAG 214
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
>BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 78.6 bits (185), Expect = 4e-13
Identities = 68/264 (25%), Positives = 114/264 (43%), Gaps = 12/264 (4%)
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLK-RERSAEVEGDYPPQFTMRLR 3175
DD G + N S +ARL V T + + ++ ++ A E YPP+F
Sbjct: 203 DDSGAQDSQQHN-----SEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPE 257
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-FHTLEIAPTNLDD 3234
+ + R+ +V G P P VSWY +G V D E+ H+L D
Sbjct: 258 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 317
Query: 3235 GGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA 3293
G Y A+N +G + L V+ K + AP F + K+ EGD +++ + A
Sbjct: 318 AGAYACVAKNRAGEATFTVQLDVLAKEHKR--APMFIYKPQS-KKVLEGDSVKLECQISA 374
Query: 3294 YPSVGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
P + W R+ ++ + R + D G++ L + V +DAG YT +A NE G +
Sbjct: 375 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTC 434
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISP 3376
+ +++V + P + + P
Sbjct: 435 NTRLDVTARPNQTLPAPKQLRVRP 458
Score = 78.2 bits (184), Expect = 5e-13
Identities = 61/211 (28%), Positives = 92/211 (43%), Gaps = 23/211 (10%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCC 3108
P F+ + P + I G + V G P P V W NG V+ ++ +M G
Sbjct: 250 PRFIQV-PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH-S 307
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L + + D G Y+C A N G+A+ +L D K + A P
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQL-----------DVLAKEHKRA-------P 349
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQFH-TLE 3226
F + + ++V V+L CQ+ PPPK+ W ++ E V ++ R + YQD TL
Sbjct: 350 MFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL 409
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I N D G Y V+A N +G +C+ L V
Sbjct: 410 IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
Score = 69.7 bits (163), Expect = 2e-10
Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG R+ V P+ V+WY +G ++ M + G L V DAG
Sbjct: 261 IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGA 320
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
Y C A N G A+ + +++V+ + + + PMFI KP+S + EG
Sbjct: 321 YACVAKNRAGEATFTVQLDVLAKE-----------------HKRAPMFIYKPQSKKVLEG 363
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
D+V +EC++ P P ++W R+
Sbjct: 364 DSVKLECQISAIPPPKLFWKRN 385
Score = 57.2 bits (132), Expect = 1e-06
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 10/192 (5%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDN----KLKYRKKLVDGLITLEVLNAVPSDSA 2662
EG ++ V P V+WY NG + + K+ +K + LI EV+ A SD+
Sbjct: 263 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI-FEVVRA--SDAG 319
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C +N G + + L V P F + L + + LEC+I P
Sbjct: 320 AYACVAKNRAGEATFTVQLDVLAKEHKRA--PMFIYKPQSKKVLEGDSVKLECQISAIPP 377
Query: 2723 PKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PK+ W ++++ + + R + G L I + +D+G YT A N
Sbjct: 378 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTR 437
Query: 2782 VNFTGRESQVSP 2793
++ T R +Q P
Sbjct: 438 LDVTARPNQTLP 449
Score = 50.8 bits (116), Expect = 8e-05
Identities = 52/257 (20%), Positives = 108/257 (42%), Gaps = 32/257 (12%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + + + + E ++ ++ G P P ++W+ + + + SD ++ G+
Sbjct: 249 PPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L + D+G Y C A+N T ++ +E + +P + +++
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK--------- 358
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQ---GL 2867
+V G ++ L+ +I P ++ W R V + R+ + Q G
Sbjct: 359 -----------KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ--FNTDRISLYQDNTGR 405
Query: 2868 YTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILIS 2926
TL + DV + ++G YT A + G N + V +P+ P + RP ++
Sbjct: 406 VTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLA 465
Query: 2927 V-GEDINI--SFRTQGE 2940
+ G+ +N+ +F +GE
Sbjct: 466 LNGKGLNVKQAFNPEGE 482
Score = 40.3 bits (90), Expect = 0.12
Identities = 30/133 (22%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F V + + G + ++ G P V W GR+V + + E+GL++L
Sbjct: 250 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 309
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
V +++G Y C A + G + V+ + P I K +L G+ +
Sbjct: 310 FEVVRASDAGAYACVAKNRAGEATFTVQLDVL-AKEHKRAPMFIYKPQSKKVL--EGDSV 366
Query: 2932 NISFRTQGEPKPK 2944
+ + P PK
Sbjct: 367 KLECQISAIPPPK 379
Score = 40.3 bits (90), Expect = 0.12
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L++ R P+F + +EG VKL C + + P + W RN ++
Sbjct: 341 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 400
Query: 2646 D--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D G +TL + + D+ Y+ + NE G + + L V
Sbjct: 401 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
>AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 347
Score = 78.6 bits (185), Expect = 4e-13
Identities = 62/233 (26%), Positives = 102/233 (43%), Gaps = 23/233 (9%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 188
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVV---DKGIRAYVAPEFC 3270
L+I + D G YE A N++G S L V D G ++P+ C
Sbjct: 189 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSC 241
Score = 74.1 bits (174), Expect = 8e-12
Identities = 53/187 (28%), Positives = 77/187 (41%), Gaps = 7/187 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 208
Query: 2769 AENSVWT 2775
A NS T
Sbjct: 209 ATNSAGT 215
Score = 58.4 bits (135), Expect = 4e-07
Identities = 59/239 (24%), Positives = 96/239 (40%), Gaps = 12/239 (5%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 200
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPR 3391
D G Y C A+N G R S + V G D S + P + S + + R R
Sbjct: 201 -DQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSPWCRHAR 258
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 42.3 bits (95), Expect = 0.030
Identities = 59/203 (29%), Positives = 90/203 (44%), Gaps = 27/203 (13%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 191
Query: 3109 LTIKDINIDDEGRYSCEATNTHG 3131
L I+ D+G+Y C ATN+ G
Sbjct: 192 LQIESSEESDQGKYECVATNSAG 214
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 78.6 bits (185), Expect = 4e-13
Identities = 86/331 (25%), Positives = 122/331 (36%), Gaps = 42/331 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 312 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 369
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 370 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 407
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 408 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 465
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 466 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 518
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 519 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 573
Query: 3354 GKVEVIGTDQTSEPRIPPVVIS-PDVPYSKE 3383
+ V+ T R+ + PD P E
Sbjct: 574 AYLTVLADQATPTNRLAALPKGRPDRPRDLE 604
Score = 59.7 bits (138), Expect = 2e-07
Identities = 83/320 (25%), Positives = 124/320 (38%), Gaps = 46/320 (14%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 320 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 378
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 379 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 432
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 433 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 478
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 479 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 524
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 525 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 579
Query: 2904 --QPSDLDGKPAVIVGRPEK 2921
Q + + A+ GRP++
Sbjct: 580 ADQATPTNRLAALPKGRPDR 599
Score = 50.0 bits (114), Expect = 1e-04
Identities = 85/356 (23%), Positives = 139/356 (39%), Gaps = 50/356 (14%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 28 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 87
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 88 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 140
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A
Sbjct: 141 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNAR----------- 185
Query: 2782 VNFTGRESQVSPNVVTAEKTR-IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+FT Q +P + TR +A ++ P + V RG + L+ G P
Sbjct: 186 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ--GTASSQMVLRGMDLLLECIASGVP 243
Query: 2841 TR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W ++G + + + E L +++V+E +SG Y C A + G++ +
Sbjct: 244 TPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 299
Query: 2900 ITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
+ V P LD +P K+++++ GED + R G PKP V + GEP
Sbjct: 300 VRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGEP 345
Score = 48.8 bits (111), Expect = 3e-04
Identities = 87/363 (23%), Positives = 139/363 (38%), Gaps = 57/363 (15%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 124 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 180
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
SC A T+T + + + L V+T R V E +G Q +R D
Sbjct: 181 SCNARFHFTHTIQQKNPFT-LKVLTTRGVAERTPSFMYP-----QGTASSQMVLRGMD-- 232
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ L C G P P ++WYK G ++ DK K+++ L I + +D G Y
Sbjct: 233 ------LLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEEDSGEY 283
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N G++ H +R AP + + L L G++ R+ P
Sbjct: 284 FCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGNPKPT 336
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTSGKVE 3357
V W +G P + A +R+ + + T VY C SNE G + V
Sbjct: 337 VQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 393
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ +PP ++SP IR + R ++C G P P + W
Sbjct: 394 VLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIPTLRW 433
Query: 3418 LRD 3420
++
Sbjct: 434 FKN 436
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 227 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 282
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 283 YFCLASNKMG 292
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 223 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 279
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 280 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 332
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 333 PKPTVQWMVNGEPLQS 348
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 78.6 bits (185), Expect = 4e-13
Identities = 86/331 (25%), Positives = 122/331 (36%), Gaps = 42/331 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 330 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 387
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 388 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 425
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 426 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 483
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 484 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 536
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 537 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 591
Query: 3354 GKVEVIGTDQTSEPRIPPVVIS-PDVPYSKE 3383
+ V+ T R+ + PD P E
Sbjct: 592 AYLTVLADQATPTNRLAALPKGRPDRPRDLE 622
Score = 59.7 bits (138), Expect = 2e-07
Identities = 83/320 (25%), Positives = 124/320 (38%), Gaps = 46/320 (14%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 338 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 396
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 397 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 450
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 451 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 496
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 497 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 542
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 543 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 597
Query: 2904 --QPSDLDGKPAVIVGRPEK 2921
Q + + A+ GRP++
Sbjct: 598 ADQATPTNRLAALPKGRPDR 617
Score = 49.6 bits (113), Expect = 2e-04
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 48/367 (13%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 125 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 181
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRER-SAEVEGDYPPQFTM---RL 3174
SC A T+T + + + L V+T+ ++ + + SA + P F
Sbjct: 182 SCNARFHFTHTIQQKNPFT-LKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTA 240
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+ V + L C G P P ++WYK G ++ DK K+++ L I + +D
Sbjct: 241 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEED 297
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y A N G++ H +R AP + + L L G++ R+
Sbjct: 298 SGEYFCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGN 350
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTS 3353
P V W +G P + A +R+ + + T VY C SNE G +
Sbjct: 351 PKPTVQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 407
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
V V+ +PP ++SP IR + R ++C G P P
Sbjct: 408 AFVSVLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIP 447
Query: 3414 DVYWLRD 3420
+ W ++
Sbjct: 448 TLRWFKN 454
Score = 48.8 bits (111), Expect = 3e-04
Identities = 85/361 (23%), Positives = 140/361 (38%), Gaps = 43/361 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 29 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 88
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 89 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 141
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A +T I
Sbjct: 142 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNARFH-FTHTIQQK 196
Query: 2782 VNFTGRESQVSP---NVVTAEKTRIARQSLESRRPHF---GNVLTDYQVARGGTIGLQVE 2835
FT + P + + + + + R P F + V RG + L+
Sbjct: 197 NPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 256
Query: 2836 IRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
G PT + W ++G + + + E L +++V+E +SG Y C A + G++
Sbjct: 257 ASGVPTPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 312
Query: 2895 DMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGE 2953
++ V P LD +P K+++++ GED + R G PKP V + GE
Sbjct: 313 RHTISVRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGE 362
Query: 2954 P 2954
P
Sbjct: 363 P 363
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 245 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 300
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 301 YFCLASNKMG 310
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 241 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 297
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 298 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 350
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 351 PKPTVQWMVNGEPLQS 366
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 78.6 bits (185), Expect = 4e-13
Identities = 86/331 (25%), Positives = 122/331 (36%), Gaps = 42/331 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 343 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 400
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 401 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 438
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 439 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 496
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 497 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 549
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 550 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 604
Query: 3354 GKVEVIGTDQTSEPRIPPVVIS-PDVPYSKE 3383
+ V+ T R+ + PD P E
Sbjct: 605 AYLTVLADQATPTNRLAALPKGRPDRPRDLE 635
Score = 59.7 bits (138), Expect = 2e-07
Identities = 83/320 (25%), Positives = 124/320 (38%), Gaps = 46/320 (14%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 351 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 409
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 410 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 464 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 509
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 510 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 555
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 556 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 610
Query: 2904 --QPSDLDGKPAVIVGRPEK 2921
Q + + A+ GRP++
Sbjct: 611 ADQATPTNRLAALPKGRPDR 630
Score = 50.0 bits (114), Expect = 1e-04
Identities = 85/356 (23%), Positives = 139/356 (39%), Gaps = 50/356 (14%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 118
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 119 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 171
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A
Sbjct: 172 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNAR----------- 216
Query: 2782 VNFTGRESQVSPNVVTAEKTR-IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+FT Q +P + TR +A ++ P + V RG + L+ G P
Sbjct: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ--GTASSQMVLRGMDLLLECIASGVP 274
Query: 2841 TR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W ++G + + + E L +++V+E +SG Y C A + G++ +
Sbjct: 275 TPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
Query: 2900 ITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
+ V P LD +P K+++++ GED + R G PKP V + GEP
Sbjct: 331 VRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGEP 376
Score = 48.8 bits (111), Expect = 3e-04
Identities = 87/363 (23%), Positives = 139/363 (38%), Gaps = 57/363 (15%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 211
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
SC A T+T + + + L V+T R V E +G Q +R D
Sbjct: 212 SCNARFHFTHTIQQKNPFT-LKVLTTRGVAERTPSFMYP-----QGTASSQMVLRGMD-- 263
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ L C G P P ++WYK G ++ DK K+++ L I + +D G Y
Sbjct: 264 ------LLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEEDSGEY 314
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N G++ H +R AP + + L L G++ R+ P
Sbjct: 315 FCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGNPKPT 367
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTSGKVE 3357
V W +G P + A +R+ + + T VY C SNE G + V
Sbjct: 368 VQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 424
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ +PP ++SP IR + R ++C G P P + W
Sbjct: 425 VLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIPTLRW 464
Query: 3418 LRD 3420
++
Sbjct: 465 FKN 467
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 258 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 313
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 314 YFCLASNKMG 323
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 254 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 310
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 311 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 363
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 364 PKPTVQWMVNGEPLQS 379
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 78.6 bits (185), Expect = 4e-13
Identities = 86/331 (25%), Positives = 122/331 (36%), Gaps = 42/331 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 343 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 400
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 401 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 438
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 439 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 496
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 497 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 549
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 550 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 604
Query: 3354 GKVEVIGTDQTSEPRIPPVVIS-PDVPYSKE 3383
+ V+ T R+ + PD P E
Sbjct: 605 AYLTVLADQATPTNRLAALPKGRPDRPRDLE 635
Score = 59.7 bits (138), Expect = 2e-07
Identities = 83/320 (25%), Positives = 124/320 (38%), Gaps = 46/320 (14%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 351 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 409
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 410 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 464 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 509
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 510 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 555
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 556 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 610
Query: 2904 --QPSDLDGKPAVIVGRPEK 2921
Q + + A+ GRP++
Sbjct: 611 ADQATPTNRLAALPKGRPDR 630
Score = 50.0 bits (114), Expect = 1e-04
Identities = 85/356 (23%), Positives = 139/356 (39%), Gaps = 50/356 (14%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 118
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 119 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 171
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A
Sbjct: 172 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNAR----------- 216
Query: 2782 VNFTGRESQVSPNVVTAEKTR-IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+FT Q +P + TR +A ++ P + V RG + L+ G P
Sbjct: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ--GTASSQMVLRGMDLLLECIASGVP 274
Query: 2841 TR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W ++G + + + E L +++V+E +SG Y C A + G++ +
Sbjct: 275 TPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
Query: 2900 ITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
+ V P LD +P K+++++ GED + R G PKP V + GEP
Sbjct: 331 VRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGEP 376
Score = 48.8 bits (111), Expect = 3e-04
Identities = 87/363 (23%), Positives = 139/363 (38%), Gaps = 57/363 (15%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 211
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
SC A T+T + + + L V+T R V E +G Q +R D
Sbjct: 212 SCNARFHFTHTIQQKNPFT-LKVLTTRGVAERTPSFMYP-----QGTASSQMVLRGMD-- 263
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ L C G P P ++WYK G ++ DK K+++ L I + +D G Y
Sbjct: 264 ------LLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEEDSGEY 314
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N G++ H +R AP + + L L G++ R+ P
Sbjct: 315 FCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGNPKPT 367
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTSGKVE 3357
V W +G P + A +R+ + + T VY C SNE G + V
Sbjct: 368 VQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 424
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ +PP ++SP IR + R ++C G P P + W
Sbjct: 425 VLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIPTLRW 464
Query: 3418 LRD 3420
++
Sbjct: 465 FKN 467
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 258 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 313
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 314 YFCLASNKMG 323
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 254 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 310
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 311 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 363
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 364 PKPTVQWMVNGEPLQS 379
>AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 78.6 bits (185), Expect = 4e-13
Identities = 68/264 (25%), Positives = 114/264 (43%), Gaps = 12/264 (4%)
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLK-RERSAEVEGDYPPQFTMRLR 3175
DD G + N S +ARL V T + + ++ ++ A E YPP+F
Sbjct: 203 DDSGAQDSQQHN-----SEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPE 257
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-FHTLEIAPTNLDD 3234
+ + R+ +V G P P VSWY +G V D E+ H+L D
Sbjct: 258 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 317
Query: 3235 GGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA 3293
G Y A+N +G + L V+ K + AP F + K+ EGD +++ + A
Sbjct: 318 AGAYACVAKNRAGEATFTVQLDVLAKEHKR--APMFIYKPQS-KKVLEGDSVKLECQISA 374
Query: 3294 YPSVGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
P + W R+ ++ + R + D G++ L + V +DAG YT +A NE G +
Sbjct: 375 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTC 434
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISP 3376
+ +++V + P + + P
Sbjct: 435 NTRLDVTARPNQTLPAPKQLRVRP 458
Score = 78.2 bits (184), Expect = 5e-13
Identities = 61/211 (28%), Positives = 92/211 (43%), Gaps = 23/211 (10%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCC 3108
P F+ + P + I G + V G P P V W NG V+ ++ +M G
Sbjct: 250 PRFIQV-PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH-S 307
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L + + D G Y+C A N G+A+ +L D K + A P
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQL-----------DVLAKEHKRA-------P 349
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQFH-TLE 3226
F + + ++V V+L CQ+ PPPK+ W ++ E V ++ R + YQD TL
Sbjct: 350 MFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL 409
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I N D G Y V+A N +G +C+ L V
Sbjct: 410 IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
Score = 69.7 bits (163), Expect = 2e-10
Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG R+ V P+ V+WY +G ++ M + G L V DAG
Sbjct: 261 IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGA 320
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
Y C A N G A+ + +++V+ + + + PMFI KP+S + EG
Sbjct: 321 YACVAKNRAGEATFTVQLDVLAKE-----------------HKRAPMFIYKPQSKKVLEG 363
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
D+V +EC++ P P ++W R+
Sbjct: 364 DSVKLECQISAIPPPKLFWKRN 385
Score = 57.2 bits (132), Expect = 1e-06
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 10/192 (5%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDN----KLKYRKKLVDGLITLEVLNAVPSDSA 2662
EG ++ V P V+WY NG + + K+ +K + LI EV+ A SD+
Sbjct: 263 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI-FEVVRA--SDAG 319
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C +N G + + L V P F + L + + LEC+I P
Sbjct: 320 AYACVAKNRAGEATFTVQLDVLAKEHKRA--PMFIYKPQSKKVLEGDSVKLECQISAIPP 377
Query: 2723 PKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PK+ W ++++ + + R + G L I + +D+G YT A N
Sbjct: 378 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTR 437
Query: 2782 VNFTGRESQVSP 2793
++ T R +Q P
Sbjct: 438 LDVTARPNQTLP 449
Score = 50.8 bits (116), Expect = 8e-05
Identities = 52/257 (20%), Positives = 108/257 (42%), Gaps = 32/257 (12%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + + + + E ++ ++ G P P ++W+ + + + SD ++ G+
Sbjct: 249 PPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L + D+G Y C A+N T ++ +E + +P + +++
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK--------- 358
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQ---GL 2867
+V G ++ L+ +I P ++ W R V + R+ + Q G
Sbjct: 359 -----------KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ--FNTDRISLYQDNTGR 405
Query: 2868 YTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILIS 2926
TL + DV + ++G YT A + G N + V +P+ P + RP ++
Sbjct: 406 VTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLA 465
Query: 2927 V-GEDINI--SFRTQGE 2940
+ G+ +N+ +F +GE
Sbjct: 466 LNGKGLNVKQAFNPEGE 482
Score = 40.3 bits (90), Expect = 0.12
Identities = 30/133 (22%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F V + + G + ++ G P V W GR+V + + E+GL++L
Sbjct: 250 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 309
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
V +++G Y C A + G + V+ + P I K +L G+ +
Sbjct: 310 FEVVRASDAGAYACVAKNRAGEATFTVQLDVL-AKEHKRAPMFIYKPQSKKVL--EGDSV 366
Query: 2932 NISFRTQGEPKPK 2944
+ + P PK
Sbjct: 367 KLECQISAIPPPK 379
Score = 40.3 bits (90), Expect = 0.12
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L++ R P+F + +EG VKL C + + P + W RN ++
Sbjct: 341 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 400
Query: 2646 D--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D G +TL + + D+ Y+ + NE G + + L V
Sbjct: 401 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
>AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein protein.
Length = 498
Score = 78.6 bits (185), Expect = 4e-13
Identities = 68/264 (25%), Positives = 114/264 (43%), Gaps = 12/264 (4%)
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLK-RERSAEVEGDYPPQFTMRLR 3175
DD G + N S +ARL V T + + ++ ++ A E YPP+F
Sbjct: 203 DDSGAQDSQQHN-----SEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPE 257
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ-FHTLEIAPTNLDD 3234
+ + R+ +V G P P VSWY +G V D E+ H+L D
Sbjct: 258 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 317
Query: 3235 GGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEA 3293
G Y A+N +G + L V+ K + AP F + K+ EGD +++ + A
Sbjct: 318 AGAYACVAKNRAGEATFTVQLDVLAKEHKR--APMFIYKPQS-KKVLEGDSVKLECQISA 374
Query: 3294 YPSVGVTWYRDGVRLR-PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAST 3352
P + W R+ ++ + R + D G++ L + V +DAG YT +A NE G +
Sbjct: 375 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTC 434
Query: 3353 SGKVEVIGTDQTSEPRIPPVVISP 3376
+ +++V + P + + P
Sbjct: 435 NTRLDVTARPNQTLPAPKQLRVRP 458
Score = 78.2 bits (184), Expect = 5e-13
Identities = 61/211 (28%), Positives = 92/211 (43%), Gaps = 23/211 (10%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVE-EEAGRMTSQFNGFDCC 3108
P F+ + P + I G + V G P P V W NG V+ ++ +M G
Sbjct: 250 PRFIQV-PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH-S 307
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L + + D G Y+C A N G+A+ +L D K + A P
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQL-----------DVLAKEHKRA-------P 349
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQFH-TLE 3226
F + + ++V V+L CQ+ PPPK+ W ++ E V ++ R + YQD TL
Sbjct: 350 MFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL 409
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I N D G Y V+A N +G +C+ L V
Sbjct: 410 IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
Score = 69.7 bits (163), Expect = 2e-10
Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ EG R+ V P+ V+WY +G ++ M + G L V DAG
Sbjct: 261 IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGA 320
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREG 3398
Y C A N G A+ + +++V+ + + + PMFI KP+S + EG
Sbjct: 321 YACVAKNRAGEATFTVQLDVLAKE-----------------HKRAPMFIYKPQSKKVLEG 363
Query: 3399 DTVIIECEVVGDPKPDVYWLRD 3420
D+V +EC++ P P ++W R+
Sbjct: 364 DSVKLECQISAIPPPKLFWKRN 385
Score = 57.2 bits (132), Expect = 1e-06
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 10/192 (5%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDN----KLKYRKKLVDGLITLEVLNAVPSDSA 2662
EG ++ V P V+WY NG + + K+ +K + LI EV+ A SD+
Sbjct: 263 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI-FEVVRA--SDAG 319
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y+C +N G + + L V P F + L + + LEC+I P
Sbjct: 320 AYACVAKNRAGEATFTVQLDVLAKEHKRA--PMFIYKPQSKKVLEGDSVKLECQISAIPP 377
Query: 2723 PKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
PK+ W ++++ + + R + G L I + +D+G YT A N
Sbjct: 378 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTR 437
Query: 2782 VNFTGRESQVSP 2793
++ T R +Q P
Sbjct: 438 LDVTARPNQTLP 449
Score = 50.8 bits (116), Expect = 8e-05
Identities = 52/257 (20%), Positives = 108/257 (42%), Gaps = 32/257 (12%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + + + + E ++ ++ G P P ++W+ + + + SD ++ G+
Sbjct: 249 PPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307
Query: 2752 LAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESR 2811
L + D+G Y C A+N T ++ +E + +P + +++
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK--------- 358
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQ---GL 2867
+V G ++ L+ +I P ++ W R V + R+ + Q G
Sbjct: 359 -----------KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ--FNTDRISLYQDNTGR 405
Query: 2868 YTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV-VQPSDLDGKPAVIVGRPEKDILIS 2926
TL + DV + ++G YT A + G N + V +P+ P + RP ++
Sbjct: 406 VTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLA 465
Query: 2927 V-GEDINI--SFRTQGE 2940
+ G+ +N+ +F +GE
Sbjct: 466 LNGKGLNVKQAFNPEGE 482
Score = 40.3 bits (90), Expect = 0.12
Identities = 30/133 (22%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F V + + G + ++ G P V W GR+V + + E+GL++L
Sbjct: 250 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 309
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDI 2931
V +++G Y C A + G + V+ + P I K +L G+ +
Sbjct: 310 FEVVRASDAGAYACVAKNRAGEATFTVQLDVL-AKEHKRAPMFIYKPQSKKVL--EGDSV 366
Query: 2932 NISFRTQGEPKPK 2944
+ + P PK
Sbjct: 367 KLECQISAIPPPK 379
Score = 40.3 bits (90), Expect = 0.12
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L++ R P+F + +EG VKL C + + P + W RN ++
Sbjct: 341 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 400
Query: 2646 D--GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
D G +TL + + D+ Y+ + NE G + + L V
Sbjct: 401 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
>BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein.
Length = 294
Score = 78.2 bits (184), Expect = 5e-13
Identities = 81/307 (26%), Positives = 115/307 (37%), Gaps = 41/307 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 18 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 75
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 76 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 113
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 114 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 171
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 172 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 224
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 225 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 279
Query: 3354 GKVEVIG 3360
+ V+G
Sbjct: 280 AYLTVLG 286
Score = 56.8 bits (131), Expect = 1e-06
Identities = 75/284 (26%), Positives = 108/284 (38%), Gaps = 44/284 (15%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 26 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 84
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 85 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 138
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 139 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 184
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 185 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 230
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
WL++ +Y R+ E +L + V E + G YTC A
Sbjct: 231 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVA 269
Score = 56.0 bits (129), Expect = 2e-06
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 35/238 (14%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
RL C+ G+P P V W +GE + N ++ T+ T + VY+ N
Sbjct: 30 RLVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 88
Query: 3246 SGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G + + + V V P L ++ + R+ P + W+++G
Sbjct: 89 HGYLLANAFVSV-----LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 143
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ +G +E+ + + D G+YTC A+N +G+A ++EV
Sbjct: 144 QGSNLDGGNYHVYE-NGSLEIKM--IRKEDQGIYTCVATNILGKAENQVRLEV------- 193
Query: 3366 EPRIPPVVISPDVPYSKEPMFI-RKPRSSEAREGDTVIIECEVVGDP--KPDVYWLRD 3420
K+P I R P AR G TV +EC V DP K V WL+D
Sbjct: 194 ----------------KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 235
Score = 48.0 bits (109), Expect = 6e-04
Identities = 46/180 (25%), Positives = 67/180 (37%), Gaps = 16/180 (8%)
Query: 2609 SRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTV 2668
+R +L C S PT+ W++NG + L V +LE+ D Y+C
Sbjct: 121 NRTRLDCPFFGSPIPTLRWFKNGQ--GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 178
Query: 2669 ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT-- 2726
N G L+V P R D + LECR++ P K+T
Sbjct: 179 TNILGKAENQVRLEVKD-------PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVS 231
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W KDD+ + R + D L I D G+YTC A + D ++ G
Sbjct: 232 WLKDDEPLYIGNRMKK---EDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLG 286
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 78.2 bits (184), Expect = 5e-13
Identities = 81/307 (26%), Positives = 115/307 (37%), Gaps = 41/307 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 337 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 394
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 395 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 432
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 433 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 490
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 491 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 543
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 544 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 598
Query: 3354 GKVEVIG 3360
+ V+G
Sbjct: 599 AYLTVLG 605
Score = 57.2 bits (132), Expect = 1e-06
Identities = 81/310 (26%), Positives = 119/310 (38%), Gaps = 48/310 (15%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 345 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 403
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 404 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 457
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 458 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 503
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 504 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 549
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 550 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 604
Query: 2904 ----QPSDLD 2909
+P DL+
Sbjct: 605 GRPDRPRDLE 614
Score = 56.0 bits (129), Expect = 2e-06
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 35/238 (14%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
RL C+ G+P P V W +GE + N ++ T+ T + VY+ N
Sbjct: 349 RLVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 407
Query: 3246 SGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G + + + V V P L ++ + R+ P + W+++G
Sbjct: 408 HGYLLANAFVSV-----LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 462
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ +G +E+ + + D G+YTC A+N +G+A ++EV
Sbjct: 463 QGSNLDGGNYHVYE-NGSLEIKM--IRKEDQGIYTCVATNILGKAENQVRLEV------- 512
Query: 3366 EPRIPPVVISPDVPYSKEPMFI-RKPRSSEAREGDTVIIECEVVGDP--KPDVYWLRD 3420
K+P I R P AR G TV +EC V DP K V WL+D
Sbjct: 513 ----------------KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 554
Score = 50.0 bits (114), Expect = 1e-04
Identities = 85/356 (23%), Positives = 139/356 (39%), Gaps = 50/356 (14%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 112
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 113 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 165
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A
Sbjct: 166 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNAR----------- 210
Query: 2782 VNFTGRESQVSPNVVTAEKTR-IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+FT Q +P + TR +A ++ P + V RG + L+ G P
Sbjct: 211 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ--GTASSQMVLRGMDLLLECIASGVP 268
Query: 2841 TR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W ++G + + + E L +++V+E +SG Y C A + G++ +
Sbjct: 269 TPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 324
Query: 2900 ITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
+ V P LD +P K+++++ GED + R G PKP V + GEP
Sbjct: 325 VRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGEP 370
Score = 48.8 bits (111), Expect = 3e-04
Identities = 87/363 (23%), Positives = 139/363 (38%), Gaps = 57/363 (15%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 149 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 205
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
SC A T+T + + + L V+T R V E +G Q +R D
Sbjct: 206 SCNARFHFTHTIQQKNPFT-LKVLTTRGVAERTPSFMYP-----QGTASSQMVLRGMD-- 257
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ L C G P P ++WYK G ++ DK K+++ L I + +D G Y
Sbjct: 258 ------LLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEEDSGEY 308
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N G++ H +R AP + + L L G++ R+ P
Sbjct: 309 FCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGNPKPT 361
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTSGKVE 3357
V W +G P + A +R+ + + T VY C SNE G + V
Sbjct: 362 VQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 418
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ +PP ++SP IR + R ++C G P P + W
Sbjct: 419 VLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIPTLRW 458
Query: 3418 LRD 3420
++
Sbjct: 459 FKN 461
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 252 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 307
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 308 YFCLASNKMG 317
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 248 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 304
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 305 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 357
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 358 PKPTVQWMVNGEPLQS 373
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 78.2 bits (184), Expect = 5e-13
Identities = 81/307 (26%), Positives = 115/307 (37%), Gaps = 41/307 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 354 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 411
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 412 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 449
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 450 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 507
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 508 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 560
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 561 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 615
Query: 3354 GKVEVIG 3360
+ V+G
Sbjct: 616 AYLTVLG 622
Score = 57.2 bits (132), Expect = 1e-06
Identities = 81/310 (26%), Positives = 119/310 (38%), Gaps = 48/310 (15%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 362 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 420
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 421 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 475 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 520
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 521 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 566
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 567 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 621
Query: 2904 ----QPSDLD 2909
+P DL+
Sbjct: 622 GRPDRPRDLE 631
Score = 56.0 bits (129), Expect = 2e-06
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 35/238 (14%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
RL C+ G+P P V W +GE + N ++ T+ T + VY+ N
Sbjct: 366 RLVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 424
Query: 3246 SGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G + + + V V P L ++ + R+ P + W+++G
Sbjct: 425 HGYLLANAFVSV-----LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 479
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ +G +E+ + + D G+YTC A+N +G+A ++EV
Sbjct: 480 QGSNLDGGNYHVYE-NGSLEIKM--IRKEDQGIYTCVATNILGKAENQVRLEV------- 529
Query: 3366 EPRIPPVVISPDVPYSKEPMFI-RKPRSSEAREGDTVIIECEVVGDP--KPDVYWLRD 3420
K+P I R P AR G TV +EC V DP K V WL+D
Sbjct: 530 ----------------KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 571
Score = 49.6 bits (113), Expect = 2e-04
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 48/367 (13%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 149 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 205
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRER-SAEVEGDYPPQFTM---RL 3174
SC A T+T + + + L V+T+ ++ + + SA + P F
Sbjct: 206 SCNARFHFTHTIQQKNPFT-LKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTA 264
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+ V + L C G P P ++WYK G ++ DK K+++ L I + +D
Sbjct: 265 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEED 321
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y A N G++ H +R AP + + L L G++ R+
Sbjct: 322 SGEYFCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGN 374
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTS 3353
P V W +G P + A +R+ + + T VY C SNE G +
Sbjct: 375 PKPTVQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 431
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
V V+ +PP ++SP IR + R ++C G P P
Sbjct: 432 AFVSVLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIP 471
Query: 3414 DVYWLRD 3420
+ W ++
Sbjct: 472 TLRWFKN 478
Score = 48.8 bits (111), Expect = 3e-04
Identities = 85/361 (23%), Positives = 140/361 (38%), Gaps = 43/361 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 112
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 113 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 165
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A +T I
Sbjct: 166 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNARFH-FTHTIQQK 220
Query: 2782 VNFTGRESQVSP---NVVTAEKTRIARQSLESRRPHF---GNVLTDYQVARGGTIGLQVE 2835
FT + P + + + + + R P F + V RG + L+
Sbjct: 221 NPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 280
Query: 2836 IRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
G PT + W ++G + + + E L +++V+E +SG Y C A + G++
Sbjct: 281 ASGVPTPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 336
Query: 2895 DMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGE 2953
++ V P LD +P K+++++ GED + R G PKP V + GE
Sbjct: 337 RHTISVRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGE 386
Query: 2954 P 2954
P
Sbjct: 387 P 387
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 269 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 324
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 325 YFCLASNKMG 334
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 265 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 321
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 322 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 374
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 375 PKPTVQWMVNGEPLQS 390
>AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 619
Score = 78.2 bits (184), Expect = 5e-13
Identities = 81/307 (26%), Positives = 115/307 (37%), Gaps = 41/307 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 343 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 400
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 401 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 438
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 439 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 496
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 497 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 549
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 550 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 604
Query: 3354 GKVEVIG 3360
+ V+G
Sbjct: 605 AYLTVLG 611
Score = 56.8 bits (131), Expect = 1e-06
Identities = 75/284 (26%), Positives = 108/284 (38%), Gaps = 44/284 (15%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 351 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 409
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 410 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 464 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 509
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 510 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 555
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
WL++ +Y R+ E +L + V E + G YTC A
Sbjct: 556 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVA 594
Score = 56.0 bits (129), Expect = 2e-06
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 35/238 (14%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
RL C+ G+P P V W +GE + N ++ T+ T + VY+ N
Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 413
Query: 3246 SGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G + + + V V P L ++ + R+ P + W+++G
Sbjct: 414 HGYLLANAFVSV-----LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ +G +E+ + + D G+YTC A+N +G+A ++EV
Sbjct: 469 QGSNLDGGNYHVYE-NGSLEIKM--IRKEDQGIYTCVATNILGKAENQVRLEV------- 518
Query: 3366 EPRIPPVVISPDVPYSKEPMFI-RKPRSSEAREGDTVIIECEVVGDP--KPDVYWLRD 3420
K+P I R P AR G TV +EC V DP K V WL+D
Sbjct: 519 ----------------KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
Score = 50.0 bits (114), Expect = 1e-04
Identities = 85/356 (23%), Positives = 139/356 (39%), Gaps = 50/356 (14%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 118
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 119 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 171
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A
Sbjct: 172 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNAR----------- 216
Query: 2782 VNFTGRESQVSPNVVTAEKTR-IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
+FT Q +P + TR +A ++ P + V RG + L+ G P
Sbjct: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ--GTASSQMVLRGMDLLLECIASGVP 274
Query: 2841 TR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W ++G + + + E L +++V+E +SG Y C A + G++ +
Sbjct: 275 TPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
Query: 2900 ITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
+ V P LD +P K+++++ GED + R G PKP V + GEP
Sbjct: 331 VRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGEP 376
Score = 48.8 bits (111), Expect = 3e-04
Identities = 87/363 (23%), Positives = 139/363 (38%), Gaps = 57/363 (15%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 211
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
SC A T+T + + + L V+T R V E +G Q +R D
Sbjct: 212 SCNARFHFTHTIQQKNPFT-LKVLTTRGVAERTPSFMYP-----QGTASSQMVLRGMD-- 263
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ L C G P P ++WYK G ++ DK K+++ L I + +D G Y
Sbjct: 264 ------LLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEEDSGEY 314
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
A N G++ H +R AP + + L L G++ R+ P
Sbjct: 315 FCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGNPKPT 367
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTSGKVE 3357
V W +G P + A +R+ + + T VY C SNE G + V
Sbjct: 368 VQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 424
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ +PP ++SP IR + R ++C G P P + W
Sbjct: 425 VLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIPTLRW 464
Query: 3418 LRD 3420
++
Sbjct: 465 FKN 467
Score = 48.0 bits (109), Expect = 6e-04
Identities = 46/180 (25%), Positives = 67/180 (37%), Gaps = 16/180 (8%)
Query: 2609 SRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTV 2668
+R +L C S PT+ W++NG + L V +LE+ D Y+C
Sbjct: 446 NRTRLDCPFFGSPIPTLRWFKNGQ--GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
Query: 2669 ENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT-- 2726
N G L+V P R D + LECR++ P K+T
Sbjct: 504 TNILGKAENQVRLEVKD-------PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVS 556
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
W KDD+ + R + D L I D G+YTC A + D ++ G
Sbjct: 557 WLKDDEPLYIGNRMKK---EDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLG 611
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 258 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 313
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 314 YFCLASNKMG 323
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 254 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 310
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 311 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 363
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 364 PKPTVQWMVNGEPLQS 379
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 78.2 bits (184), Expect = 5e-13
Identities = 81/307 (26%), Positives = 115/307 (37%), Gaps = 41/307 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 151 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 208
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 209 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 246
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 247 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 304
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 305 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 357
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 358 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 412
Query: 3354 GKVEVIG 3360
+ V+G
Sbjct: 413 AYLTVLG 419
Score = 57.2 bits (132), Expect = 1e-06
Identities = 81/310 (26%), Positives = 119/310 (38%), Gaps = 48/310 (15%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 159 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 217
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 218 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 271
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 272 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 317
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 318 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 363
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 364 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 418
Query: 2904 ----QPSDLD 2909
+P DL+
Sbjct: 419 GRPDRPRDLE 428
Score = 56.0 bits (129), Expect = 2e-06
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 35/238 (14%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
RL C+ G+P P V W +GE + N ++ T+ T + VY+ N
Sbjct: 163 RLVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 221
Query: 3246 SGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G + + + V V P L ++ + R+ P + W+++G
Sbjct: 222 HGYLLANAFVSV-----LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 276
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ +G +E+ + + D G+YTC A+N +G+A ++EV
Sbjct: 277 QGSNLDGGNYHVYE-NGSLEIKM--IRKEDQGIYTCVATNILGKAENQVRLEV------- 326
Query: 3366 EPRIPPVVISPDVPYSKEPMFI-RKPRSSEAREGDTVIIECEVVGDP--KPDVYWLRD 3420
K+P I R P AR G TV +EC V DP K V WL+D
Sbjct: 327 ----------------KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 368
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/65 (40%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSD-GRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+L+LEC G P P I W+K +PSD +++ F A L I N + EDSG Y C
Sbjct: 71 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA-----LRITNVSEEDSGEYFCL 125
Query: 2769 AENSV 2773
A N +
Sbjct: 126 ASNKM 130
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 66 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 121
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 122 YFCLASNKMG 131
Score = 42.3 bits (95), Expect = 0.030
Identities = 57/235 (24%), Positives = 91/235 (38%), Gaps = 34/235 (14%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L C G P P ++WYK G ++ DK K+++ L I + +D G Y A N
Sbjct: 74 LECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEEDSGEYFCLASNKM 130
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G++ H +R AP + + L L G++ R+ P V W +G
Sbjct: 131 GSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGNPKPTVQWMVNG- 182
Query: 3307 RLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
P + A +R+ + + T VY C SNE G + V V+
Sbjct: 183 --EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD----- 235
Query: 3366 EPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP ++SP IR + R ++C G P P + W ++
Sbjct: 236 ---VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIPTLRWFKN 275
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 62 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 118
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 119 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 171
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 172 PKPTVQWMVNGEPLQS 187
Score = 39.9 bits (89), Expect = 0.16
Identities = 45/175 (25%), Positives = 78/175 (44%), Gaps = 19/175 (10%)
Query: 2783 NFTGRESQVSPNVVTAEKTR-IARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT 2841
+FT Q +P + TR +A ++ P + V RG + L+ G PT
Sbjct: 26 HFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ--GTASSQMVLRGMDLLLECIASGVPT 83
Query: 2842 R-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAI 2900
+ W ++G + + + E L +++V+E +SG Y C A + G++ ++
Sbjct: 84 PDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISV 139
Query: 2901 TV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEP 2954
V P LD +P K+++++ GED + R G PKP V + GEP
Sbjct: 140 RVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGEP 184
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 78.2 bits (184), Expect = 5e-13
Identities = 81/307 (26%), Positives = 115/307 (37%), Gaps = 41/307 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P V WM NG ++ + G + +D I
Sbjct: 407 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT--IIFRDTQI 464
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQF-TMRLR 3175
Y C +N HG A ++V+ D PP+ + R +
Sbjct: 465 SSRAVYQCNTSNEHGYLLANAFVSVL----------------------DVPPRMLSPRNQ 502
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
RV RL C GSP P + W+K+G+ D Y + +LEI +D
Sbjct: 503 LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG--GNYHVYENGSLEIKMIRKEDQ 560
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G+Y A N G L V R Y PE G +++ V+ P
Sbjct: 561 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA-------RRGTTVQLECRVKHDP 613
Query: 3296 SVGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
S+ +T W +D L R M + D L + V RD G YTC AS E+ +
Sbjct: 614 SLKLTVSWLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAK 668
Query: 3354 GKVEVIG 3360
+ V+G
Sbjct: 669 AYLTVLG 675
Score = 57.2 bits (132), Expect = 1e-06
Identities = 81/310 (26%), Positives = 119/310 (38%), Gaps = 48/310 (15%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G +L C + PTV W NG L + + V G T+ + S A Y C
Sbjct: 415 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCN 473
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH-LAENELVLECRIRGQPLPKIT 2726
NE+G + +A + V +PP + N L+C G P+P +
Sbjct: 474 TSNEHGYLLANAFVSVLD------VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 527
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTG 2786
WFK+ + DG Y +G L I ED G YTC A N +
Sbjct: 528 WFKNGQGSNLDGGNYHVY-ENG--SLEIKMIRKEDQGIYTCVATNILGK----------- 573
Query: 2787 RESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT---RV 2843
E+QV V + TRI R D RG T+ L+ ++ P+ V
Sbjct: 574 AENQVRLEV--KDPTRIYRMP------------EDQVARRGTTVQLECRVKHDPSLKLTV 619
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
WL++ +Y R+ E +L + V E + G YTC A + A +TV+
Sbjct: 620 SWLKDDE---PLYIGNRMKKEDD--SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 674
Query: 2904 ----QPSDLD 2909
+P DL+
Sbjct: 675 GRPDRPRDLE 684
Score = 56.0 bits (129), Expect = 2e-06
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 35/238 (14%)
Query: 3186 RLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNN 3245
RL C+ G+P P V W +GE + N ++ T+ T + VY+ N
Sbjct: 419 RLVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 477
Query: 3246 SGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G + + + V V P L ++ + R+ P + W+++G
Sbjct: 478 HGYLLANAFVSV-----LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 532
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTS 3365
+ +G +E+ + + D G+YTC A+N +G+A ++EV
Sbjct: 533 QGSNLDGGNYHVYE-NGSLEIKM--IRKEDQGIYTCVATNILGKAENQVRLEV------- 582
Query: 3366 EPRIPPVVISPDVPYSKEPMFI-RKPRSSEAREGDTVIIECEVVGDP--KPDVYWLRD 3420
K+P I R P AR G TV +EC V DP K V WL+D
Sbjct: 583 ----------------KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 624
Score = 49.6 bits (113), Expect = 2e-04
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 48/367 (13%)
Query: 3065 GETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD-EGRY 3122
G L C+ G P P + WM + E + R++ NG L ++ + D + Y
Sbjct: 202 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD---LYFSNVMLQDMQTDY 258
Query: 3123 SCEA----TNTHGKASTYARLAVVTDRTVWEADAKLKRER-SAEVEGDYPPQFTM---RL 3174
SC A T+T + + + L V+T+ ++ + + SA + P F
Sbjct: 259 SCNARFHFTHTIQQKNPFT-LKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTA 317
Query: 3175 RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDD 3234
+ V + L C G P P ++WYK G ++ DK K+++ L I + +D
Sbjct: 318 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA--KFENFN-KALRITNVSEED 374
Query: 3235 GGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAY 3294
G Y A N G++ H +R AP + + L L G++ R+
Sbjct: 375 SGEYFCLASNKMGSIR-H-----TISVRVKAAPYWLDEPKNLI-LAPGEDGRLVCRANGN 427
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT-TRDAGVYTCTASNEVGRASTS 3353
P V W +G P + A +R+ + + T VY C SNE G +
Sbjct: 428 PKPTVQWMVNG---EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 484
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
V V+ +PP ++SP IR + R ++C G P P
Sbjct: 485 AFVSVLD--------VPPRMLSP------RNQLIRVILYNRTR------LDCPFFGSPIP 524
Query: 3414 DVYWLRD 3420
+ W ++
Sbjct: 525 TLRWFKN 531
Score = 48.8 bits (111), Expect = 3e-04
Identities = 85/361 (23%), Positives = 140/361 (38%), Gaps = 43/361 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNG----VLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+ + C + P+ W RN + D ++ R++ +I EY C
Sbjct: 106 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 165
Query: 2667 TVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
N+ G A+S L+V S P + + D + E L L+C G P P
Sbjct: 166 FARNKFGTALSNRIRLQVSKS-------PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSP 218
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAENSVWTDQITHF 2781
I W + I D R + D L N +D T Y+C A +T I
Sbjct: 219 VIFWMSSSMEPITQDKRVSQGHNGD----LYFSNVMLQDMQTDYSCNARFH-FTHTIQQK 273
Query: 2782 VNFTGRESQVSP---NVVTAEKTRIARQSLESRRPHF---GNVLTDYQVARGGTIGLQVE 2835
FT + P + + + + + R P F + V RG + L+
Sbjct: 274 NPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 333
Query: 2836 IRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNV 2894
G PT + W ++G + + + E L +++V+E +SG Y C A + G++
Sbjct: 334 ASGVPTPDIAWYKKGGDLP----SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 389
Query: 2895 DMNAAITV-VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGE 2953
++ V P LD +P K+++++ GED + R G PKP V + GE
Sbjct: 390 RHTISVRVKAAPYWLD-EP--------KNLILAPGEDGRLVCRANGNPKP-TVQWMVNGE 439
Query: 2954 P 2954
P
Sbjct: 440 P 440
Score = 44.0 bits (99), Expect = 0.010
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+L G L C G P P + W K G ++ + ++F F+ L I +++ +D G
Sbjct: 322 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD----KAKFENFNKALRITNVSEEDSGE 377
Query: 3122 YSCEATNTHG 3131
Y C A+N G
Sbjct: 378 YFCLASNKMG 387
Score = 40.7 bits (91), Expect = 0.090
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 10/136 (7%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD 2660
+ + + G + L C P + WY+ G L + + K + L + N D
Sbjct: 318 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD---KAKFENFNKALRITNVSEED 374
Query: 2661 SAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQ 2720
S EY C N+ G+I + +++V + P + ++ + L CR G
Sbjct: 375 SGEYFCLASNKMGSIRHTISVRVKAA-------PYWLDEPKNLILAPGEDGRLVCRANGN 427
Query: 2721 PLPKITWFKDDKQIPS 2736
P P + W + + + S
Sbjct: 428 PKPTVQWMVNGEPLQS 443
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 77.8 bits (183), Expect = 6e-13
Identities = 83/336 (24%), Positives = 125/336 (37%), Gaps = 33/336 (9%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAFYLADGVCRLAIDNPTP 2759
+ C G P P+ITWFKD + ++GR + ++ + L I+
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQL-RSESIGALQIEQSEE 193
Query: 2760 EDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVL 2819
D G Y C A NS G N+ E + R P F
Sbjct: 194 SDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PRFSIPP 236
Query: 2820 TDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTET 2878
T++++ GG++ + G P V+W+ +T + G L L+DV
Sbjct: 237 TNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELNDV--R 289
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
+S YTC A S G ++ A ITV G P V
Sbjct: 290 QSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 325
Score = 71.3 bits (167), Expect = 6e-11
Identities = 75/304 (24%), Positives = 120/304 (39%), Gaps = 34/304 (11%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK---RRNKYQDEQFHTLEIAPTNLDDGGVY 3238
T + C G+P P+++W+KD V R + + E L+I + D G Y
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKY 199
Query: 3239 EVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAY 3294
E A N++G S L V + +R V P F + P +++ G + I+ V
Sbjct: 200 ECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVNITCVAVGS 256
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
P V W L P M + R+ L R + YTC A + +G
Sbjct: 257 PMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMSTLGVIEAIA 309
Query: 3355 KVEV 3358
++ V
Sbjct: 310 QITV 313
Score = 65.7 bits (153), Expect = 3e-09
Identities = 68/264 (25%), Positives = 99/264 (37%), Gaps = 26/264 (9%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDGQIELALAAVTTR 3334
K+ E + P +TW++D + + S I L + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEES 194
Query: 3335 DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE 3394
D G Y C A+N G S + + R+P P F P + E
Sbjct: 195 DQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSIPPTNHE 240
Query: 3395 AREGDTVIIECEVVGDPKPDVYWL 3418
G +V I C VG P P V W+
Sbjct: 241 IMPGGSVNITCVAVGSPMPYVKWM 264
Score = 58.0 bits (134), Expect = 6e-07
Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 19/159 (11%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCL 3109
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + L
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGAL 186
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I+ D+G+Y C ATN+ G T + A A L EV PP+
Sbjct: 187 QIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVRR-VPPR 231
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
F++ + + V +TC +GSP P V W E++
Sbjct: 232 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 270
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 230 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 283
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 284 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 313
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 77.8 bits (183), Expect = 6e-13
Identities = 77/320 (24%), Positives = 128/320 (40%), Gaps = 30/320 (9%)
Query: 3041 IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTS 3100
+G A + P F+ Q+ + +G A+ C G P P V W K G +V +
Sbjct: 24 VGGCAAEEPPRFIKEPKDQIGV-SGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIE 82
Query: 3101 QFNGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
L I+ + DE Y C A N+ G+ + +A+L V+ R
Sbjct: 83 FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL---------------RE 127
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
++ +P M + + V+ T + C G+P P+++W+KD V + +
Sbjct: 128 DQLPSGFP-NIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQ 186
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
+ L+I + D G YE A N++G S L V +R VAP F L ++
Sbjct: 187 LRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYV--RVRR-VAPRFSI-LPMSHE 242
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ G + I+ V P V W + L P M + R+ L +D+
Sbjct: 243 IMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDD--MPVGRN-----VLELTDVKDSAN 295
Query: 3339 YTCTASNEVGRASTSGKVEV 3358
YTC A + +G ++ V
Sbjct: 296 YTCVAMSSLGVIEAVAQITV 315
Score = 67.7 bits (158), Expect = 7e-10
Identities = 67/260 (25%), Positives = 107/260 (41%), Gaps = 31/260 (11%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTL 3225
PP+F +D+ + CQ G P P+V+W K G++V + ++ + L
Sbjct: 32 PPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 91
Query: 3226 EIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
I P D VYE A+N+ G ++ H L V +R P ++ +L +
Sbjct: 92 RIQPLRTPRDENVYECVAQNSVGEITVHAKLTV---LREDQLPSGFPNIDMGPQLKVVER 148
Query: 3285 LRISAVV---EAYPSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
R + ++ P +TW++D + + PS + R G +++ + T D G Y
Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEET--DQGKYE 206
Query: 3341 CTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N G R S+ + V R+ V P F P S E G
Sbjct: 207 CVATNSAGVRYSSPANLYV---------RVRRVA----------PRFSILPMSHEIMPGG 247
Query: 3400 TVIIECEVVGDPKPDVYWLR 3419
V I C VG P P V W++
Sbjct: 248 NVNITCVAVGSPMPYVKWMQ 267
Score = 65.7 bits (153), Expect = 3e-09
Identities = 77/319 (24%), Positives = 121/319 (37%), Gaps = 38/319 (11%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK----LKYRKKLVDGLITLEVLNAV 2657
D+ V G C P VTW + G ++++ +++ + ++ ++ L
Sbjct: 41 DQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDES-AGAVLRIQPLRT- 98
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
P D Y C +N G I+ A L V + P + + C
Sbjct: 99 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 158
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G P P+ITWFKD + PS + L G L I++ D G Y C A NS
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA--LQIESSEETDQGKYECVATNSAG-- 214
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
V ++ SP + R+A P F + +++ GG + +
Sbjct: 215 -----VRYS------SPANLYVRVRRVA--------PRFSILPMSHEIMPGGNVNITCVA 255
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P V+W++ +T + G L L+DV +S YTC A S+ G ++
Sbjct: 256 VGSPMPYVKWMQGAEDLT-----PEDDMPVGRNVLELTDV--KDSANYTCVAMSSLGVIE 308
Query: 2896 MNAAITVVQPSDLDGKPAV 2914
A ITV G P V
Sbjct: 309 AVAQITVKSLPKAPGTPMV 327
Score = 51.2 bits (117), Expect = 6e-05
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P VTW + G ++ R + D L + + T RD VY C A N VG +
Sbjct: 60 PKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ DQ +P P++ + + + R T + C G+P P
Sbjct: 120 AKLTVLREDQ-----LPSGF--PNIDMGPQLKVVERTR--------TATMLCAASGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EITWFKDFLPV 175
Score = 47.6 bits (108), Expect = 8e-04
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 9/125 (7%)
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ PP F + +D ++ C+ G P P++TW K K++ S R++ +
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQ-RFETIEFDES 86
Query: 2749 VCRLAIDNP--TPEDSGTYTCKAENSVWTDQITHFVNFTG-RESQVS---PNVVTAEKTR 2802
+ P TP D Y C A+NSV +IT T RE Q+ PN+ + +
Sbjct: 87 AGAVLRIQPLRTPRDENVYECVAQNSV--GEITVHAKLTVLREDQLPSGFPNIDMGPQLK 144
Query: 2803 IARQS 2807
+ ++
Sbjct: 145 VVERT 149
Score = 35.5 bits (78), Expect = 3.4
Identities = 15/41 (36%), Positives = 20/41 (48%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
P FI++P+ G C+ GDPKP V W + KV
Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV 73
Score = 35.1 bits (77), Expect = 4.5
Identities = 36/148 (24%), Positives = 53/148 (35%), Gaps = 15/148 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS + G V +TC + S P V W + L + G LE+
Sbjct: 232 PRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA----EDLTPEDDMPVGRNVLEL 287
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ DSA Y+C + G I A + V S +P P T + + + +
Sbjct: 288 TDV--KDSANYTCVAMSSLGVIEAVAQITV-KSLPKAPGTPMVTENTATSITITWDS--- 341
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQ 2741
G P P + + K DG YQ
Sbjct: 342 -----GNPDPVSYYVIEYKSKSQDGPYQ 364
Score = 34.7 bits (76), Expect = 5.9
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 7/152 (4%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D GG + G P RV W ++G+ V F E L
Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 2872 LSDV-TETESGLYTCRAWSAHGNVDMNAAITVVQPSDL-DGKPAVIVGRPEKDILISVGE 2929
+ + T + +Y C A ++ G + ++A +TV++ L G P + +G K ++
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLK--VVERTR 150
Query: 2930 DINISFRTQGEPKPKAV--PERIPGEPCVVDG 2959
+ G P P+ + +P +P +G
Sbjct: 151 TATMLCAASGNPDPEITWFKDFLPVDPSASNG 182
>AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 262
Score = 77.8 bits (183), Expect = 6e-13
Identities = 60/224 (26%), Positives = 100/224 (44%), Gaps = 21/224 (9%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 188
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAY 3264
L+I + D G YE A N++G S L V +G+ A+
Sbjct: 189 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV-RGLAAW 231
Score = 74.1 bits (174), Expect = 8e-12
Identities = 53/187 (28%), Positives = 77/187 (41%), Gaps = 7/187 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 208
Query: 2769 AENSVWT 2775
A NS T
Sbjct: 209 ATNSAGT 215
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 54.8 bits (126), Expect = 5e-06
Identities = 53/208 (25%), Positives = 86/208 (41%), Gaps = 12/208 (5%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 200
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIG 3360
D G Y C A+N G R S + V G
Sbjct: 201 -DQGKYECVATNSAGTRYSAPANLYVRG 227
Score = 42.3 bits (95), Expect = 0.030
Identities = 59/203 (29%), Positives = 90/203 (44%), Gaps = 27/203 (13%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 191
Query: 3109 LTIKDINIDDEGRYSCEATNTHG 3131
L I+ D+G+Y C ATN+ G
Sbjct: 192 LQIESSEESDQGKYECVATNSAG 214
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 77.8 bits (183), Expect = 6e-13
Identities = 77/320 (24%), Positives = 128/320 (40%), Gaps = 30/320 (9%)
Query: 3041 IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTS 3100
+G A + P F+ Q+ + +G A+ C G P P V W K G +V +
Sbjct: 50 VGGCAAEEPPRFIKEPKDQIGV-SGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIE 108
Query: 3101 QFNGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
L I+ + DE Y C A N+ G+ + +A+L V+ R
Sbjct: 109 FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL---------------RE 153
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
++ +P M + + V+ T + C G+P P+++W+KD V + +
Sbjct: 154 DQLPSGFP-NIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQ 212
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
+ L+I + D G YE A N++G S L V +R VAP F L ++
Sbjct: 213 LRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYV--RVRR-VAPRFSI-LPMSHE 268
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
+ G + I+ V P V W + L P M + R+ L +D+
Sbjct: 269 IMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDD--MPVGRN-----VLELTDVKDSAN 321
Query: 3339 YTCTASNEVGRASTSGKVEV 3358
YTC A + +G ++ V
Sbjct: 322 YTCVAMSSLGVIEAVAQITV 341
Score = 67.7 bits (158), Expect = 7e-10
Identities = 67/260 (25%), Positives = 107/260 (41%), Gaps = 31/260 (11%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTL 3225
PP+F +D+ + CQ G P P+V+W K G++V + ++ + L
Sbjct: 58 PPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 117
Query: 3226 EIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
I P D VYE A+N+ G ++ H L V +R P ++ +L +
Sbjct: 118 RIQPLRTPRDENVYECVAQNSVGEITVHAKLTV---LREDQLPSGFPNIDMGPQLKVVER 174
Query: 3285 LRISAVV---EAYPSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
R + ++ P +TW++D + + PS + R G +++ + T D G Y
Sbjct: 175 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEET--DQGKYE 232
Query: 3341 CTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N G R S+ + V R+ V P F P S E G
Sbjct: 233 CVATNSAGVRYSSPANLYV---------RVRRVA----------PRFSILPMSHEIMPGG 273
Query: 3400 TVIIECEVVGDPKPDVYWLR 3419
V I C VG P P V W++
Sbjct: 274 NVNITCVAVGSPMPYVKWMQ 293
Score = 65.7 bits (153), Expect = 3e-09
Identities = 77/319 (24%), Positives = 121/319 (37%), Gaps = 38/319 (11%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK----LKYRKKLVDGLITLEVLNAV 2657
D+ V G C P VTW + G ++++ +++ + ++ ++ L
Sbjct: 67 DQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDES-AGAVLRIQPLRT- 124
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
P D Y C +N G I+ A L V + P + + C
Sbjct: 125 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 184
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G P P+ITWFKD + PS + L G L I++ D G Y C A NS
Sbjct: 185 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA--LQIESSEETDQGKYECVATNSAG-- 240
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
V ++ SP + R+A P F + +++ GG + +
Sbjct: 241 -----VRYS------SPANLYVRVRRVA--------PRFSILPMSHEIMPGGNVNITCVA 281
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P V+W++ +T + G L L+DV +S YTC A S+ G ++
Sbjct: 282 VGSPMPYVKWMQGAEDLT-----PEDDMPVGRNVLELTDV--KDSANYTCVAMSSLGVIE 334
Query: 2896 MNAAITVVQPSDLDGKPAV 2914
A ITV G P V
Sbjct: 335 AVAQITVKSLPKAPGTPMV 353
Score = 51.2 bits (117), Expect = 6e-05
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P VTW + G ++ R + D L + + T RD VY C A N VG +
Sbjct: 86 PKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 145
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ DQ +P P++ + + + R T + C G+P P
Sbjct: 146 AKLTVLREDQ-----LPSGF--PNIDMGPQLKVVERTR--------TATMLCAASGNPDP 190
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 191 EITWFKDFLPV 201
Score = 47.6 bits (108), Expect = 8e-04
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 9/125 (7%)
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ PP F + +D ++ C+ G P P++TW K K++ S R++ +
Sbjct: 54 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQ-RFETIEFDES 112
Query: 2749 VCRLAIDNP--TPEDSGTYTCKAENSVWTDQITHFVNFTG-RESQVS---PNVVTAEKTR 2802
+ P TP D Y C A+NSV +IT T RE Q+ PN+ + +
Sbjct: 113 AGAVLRIQPLRTPRDENVYECVAQNSV--GEITVHAKLTVLREDQLPSGFPNIDMGPQLK 170
Query: 2803 IARQS 2807
+ ++
Sbjct: 171 VVERT 175
Score = 35.5 bits (78), Expect = 3.4
Identities = 15/41 (36%), Positives = 20/41 (48%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
P FI++P+ G C+ GDPKP V W + KV
Sbjct: 59 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV 99
Score = 35.1 bits (77), Expect = 4.5
Identities = 36/148 (24%), Positives = 53/148 (35%), Gaps = 15/148 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS + G V +TC + S P V W + L + G LE+
Sbjct: 258 PRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA----EDLTPEDDMPVGRNVLEL 313
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
+ DSA Y+C + G I A + V S +P P T + + + +
Sbjct: 314 TDV--KDSANYTCVAMSSLGVIEAVAQITV-KSLPKAPGTPMVTENTATSITITWDS--- 367
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQ 2741
G P P + + K DG YQ
Sbjct: 368 -----GNPDPVSYYVIEYKSKSQDGPYQ 390
Score = 34.7 bits (76), Expect = 5.9
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 7/152 (4%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D GG + G P RV W ++G+ V F E L
Sbjct: 59 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118
Query: 2872 LSDV-TETESGLYTCRAWSAHGNVDMNAAITVVQPSDL-DGKPAVIVGRPEKDILISVGE 2929
+ + T + +Y C A ++ G + ++A +TV++ L G P + +G K ++
Sbjct: 119 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLK--VVERTR 176
Query: 2930 DINISFRTQGEPKPKAV--PERIPGEPCVVDG 2959
+ G P P+ + +P +P +G
Sbjct: 177 TATMLCAASGNPDPEITWFKDFLPVDPSASNG 208
>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
protein.
Length = 1484
Score = 77.4 bits (182), Expect = 9e-13
Identities = 55/206 (26%), Positives = 92/206 (44%), Gaps = 19/206 (9%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 46 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 104
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 105 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 157
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 158 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 208
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSG 3247
L+I + D G YE A N++G
Sbjct: 209 SGALQIESSEESDQGKYECVATNSAG 234
Score = 74.1 bits (174), Expect = 8e-12
Identities = 53/187 (28%), Positives = 77/187 (41%), Gaps = 7/187 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 52 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 111
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 112 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 170
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 171 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 228
Query: 2769 AENSVWT 2775
A NS T
Sbjct: 229 ATNSAGT 235
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 80 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 139
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 140 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 184
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 185 EISWFKDFLPV 195
Score = 56.0 bits (129), Expect = 2e-06
Identities = 63/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 45 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 104
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 105 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 162
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 163 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 220
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D G Y C A+N G R S + V IPP SP + + +P
Sbjct: 221 -DQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPP---SPTIQVKTQQGVPAQPAD 276
Query: 3393 SEAR-EGDTVI 3402
+A E DT I
Sbjct: 277 FQAEVESDTRI 287
Score = 44.8 bits (101), Expect = 0.006
Identities = 80/307 (26%), Positives = 128/307 (41%), Gaps = 45/307 (14%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 49 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 106
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 107 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 154
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 155 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 211
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKL-KRERSAEVEGDYP 3167
L I+ D+G+Y C ATN+ G T + A A L R R P
Sbjct: 212 LQIESSEESDQGKYECVATNSAG--------------TRYSAPANLYVRVRRVAPRFSIP 257
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEE--VVYDKRRNKYQDE-QFHT 3224
P T++++ ++ P +V ++SW +E ++Y+ +DE Q H
Sbjct: 258 PSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHK 317
Query: 3225 LEIAPTN 3231
+ PT+
Sbjct: 318 VTFDPTS 324
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 29 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 88
Query: 3420 DFLKV 3424
KV
Sbjct: 89 KGKKV 93
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 77.0 bits (181), Expect = 1e-12
Identities = 76/294 (25%), Positives = 121/294 (41%), Gaps = 46/294 (15%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE +C G P P + W +NG +EE + G + LT+++I D G Y C
Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLIEENEKYI---LKGSNTELTVRNIINSDGGPYVC 281
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
ATN G+ A L V + +LK E + E G
Sbjct: 282 RATNKAGEDEKQAFLQVFVQPHI----IQLKNETTYE-NGQ------------------- 317
Query: 3185 VRLTCQVIGSPPPKVSW--------YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
V L C G P P+++W + +G++ + + K Q +L I L D G
Sbjct: 318 VTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGS-SSLHIKDVKLSDSG 376
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y+ A + G L ++ AP+F + +Y EG+ + IS V++ P
Sbjct: 377 RYDCEAASRIGGHQKSMYLDIE------YAPKFISN-QTIYYSWEGNPINISCDVKSNPP 429
Query: 3297 VGVTWYRDGVRLRPSRRA--IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W RD + L P++ + T ++ L +A + D G Y CTA+N +G
Sbjct: 430 ASIHWRRDKLVL-PAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 72.9 bits (171), Expect = 2e-11
Identities = 73/307 (23%), Positives = 118/307 (38%), Gaps = 32/307 (10%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V I ++++ GE+ TC+ G+P + W E R+ Q G LTI
Sbjct: 23 VTISLSKVELSVGESKFFTCTAIGEP-ESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIY 81
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ NI+D G Y C+AT+ G+ EA L+ + PQ
Sbjct: 82 NANIEDAGIYRCQATDAKGQTQ--------------EATVVLEIYQKLTFREVVSPQEFK 127
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+ D V C+V SP P VSW EEV N++ + L+I N
Sbjct: 128 QGEDAEV--------VCRVSSSPAPAVSWLYHNEEVT-TISDNRFAMLANNNLQILNINK 178
Query: 3233 DDGGVYEVTARNNS-GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVV 3291
D G+Y R + G + +V+ A P+ G+E+ S
Sbjct: 179 SDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNA----TAERGEEMTFSCRA 234
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P ++W+R+G + + + I+ + EL + + D G Y C A+N+ G
Sbjct: 235 SGSPEPAISWFRNGKLIEENEKYIL---KGSNTELTVRNIINSDGGPYVCRATNKAGEDE 291
Query: 3352 TSGKVEV 3358
++V
Sbjct: 292 KQAFLQV 298
Score = 66.5 bits (155), Expect = 2e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 24/190 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT-LEVLNAVPSDSA 2662
TA G + +C S +P ++W+RNG L++ KY ++ G T L V N + SD
Sbjct: 221 TAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKY---ILKGSNTELTVRNIINSDGG 277
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C N+ G A L+V+ + P + +T + ++ L C G+P+
Sbjct: 278 PYVCRATNKAGEDEKQAFLQVF-------VQPHIIQLKNETTY-ENGQVTLVCDAEGEPI 329
Query: 2723 PKITW---------FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P+ITW + DK + DGR + G L I + DSG Y C+A + +
Sbjct: 330 PEITWKRAVDGFTFTEGDKSL--DGRIEV-KGQHGSSSLHIKDVKLSDSGRYDCEAASRI 386
Query: 2774 WTDQITHFVN 2783
Q + +++
Sbjct: 387 GGHQKSMYLD 396
Score = 62.1 bits (144), Expect = 3e-08
Identities = 49/205 (23%), Positives = 80/205 (39%), Gaps = 13/205 (6%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLK 2639
+++ T+ +K F ++ + +G ++ C V SS P V+W Y N +
Sbjct: 102 TQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDN 161
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS 2699
L + L++LN SD Y C G + + +PP +
Sbjct: 162 RFAMLANN--NLQILNINKSDEGIYRC-----EGRVEARGEIDFRDIIVIVNVPPAISMP 214
Query: 2700 IRDTFHLAE--NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNP 2757
+ AE E+ CR G P P I+WF++ K I + +Y L L + N
Sbjct: 215 QKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKY---ILKGSNTELTVRNI 271
Query: 2758 TPEDSGTYTCKAENSVWTDQITHFV 2782
D G Y C+A N D+ F+
Sbjct: 272 INSDGGPYVCRATNKAGEDEKQAFL 296
Score = 62.1 bits (144), Expect = 3e-08
Identities = 89/369 (24%), Positives = 138/369 (37%), Gaps = 69/369 (18%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE A + C V P P V W+ + EV + + + L I +IN DEG Y C
Sbjct: 129 GEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNN--LQILNINKSDEGIYRC 186
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
E G+ + R V + PP +M + A
Sbjct: 187 E-----GRVEARGEIDF----------------RDIIVIVNVPPAISMPQKSFNATAERG 225
Query: 3185 VRLT--CQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL--DDGGVYEV 3240
+T C+ GSP P +SW+++G+ + + KY + +T E+ N+ DGG Y
Sbjct: 226 EEMTFSCRASGSPEPAISWFRNGKLI---EENEKYILKGSNT-ELTVRNIINSDGGPYVC 281
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G L V +V P E Y E ++ + E P +
Sbjct: 282 RATNKAGEDEKQAFLQV------FVQPHIIQLKNETTY---ENGQVTLVCDAEGEPIPEI 332
Query: 3300 TWYR--DGVRLRPSRRA----IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
TW R DG ++ I + G L + V D+G Y C A++ +G S
Sbjct: 333 TWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKS 392
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ D+ Y+ P FI + EG+ + I C+V +P
Sbjct: 393 --------------------MYLDIEYA--PKFISNQTIYYSWEGNPINISCDVKSNPPA 430
Query: 3414 DVYWLRDFL 3422
++W RD L
Sbjct: 431 SIHWRRDKL 439
Score = 52.0 bits (119), Expect = 4e-05
Identities = 52/236 (22%), Positives = 92/236 (38%), Gaps = 32/236 (13%)
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-LEIAPTNLDDGGVYEVTARNNS 3246
TC IG P + WY E + +R Q E + L I N++D G+Y A +
Sbjct: 41 TCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAK 99
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW--YRD 3304
G +V++ Y F + P + +G++ + V + P+ V+W + +
Sbjct: 100 GQTQ-EATVVLE----IYQKLTFREVVSP-QEFKQGEDAEVVCRVSSSPAPAVSWLYHNE 153
Query: 3305 GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQT 3364
V R M + + L + + D G+Y C GR G+++ D
Sbjct: 154 EVTTISDNRFAMLANNN----LQILNINKSDEGIYRCE-----GRVEARGEIDF--RDII 202
Query: 3365 SEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + P +K ++ A G+ + C G P+P + W R+
Sbjct: 203 VIVNVPPAISMP-----------QKSFNATAERGEEMTFSCRASGSPEPAISWFRN 247
Score = 44.0 bits (99), Expect = 0.010
Identities = 43/184 (23%), Positives = 66/184 (35%), Gaps = 15/184 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYR--NGVLL---DNKL--KYRKKLVDGLITLE 2652
L + T E +V L C P +TW R +G D L + K G +L
Sbjct: 307 LKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLH 366
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + SDS Y C + G S L + P F + + N +
Sbjct: 367 IKDVKLSDSGRYDCEAASRIGGHQKSMYLDI-------EYAPKFISNQTIYYSWEGNPIN 419
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPE-DSGTYTCKAEN 2771
+ C ++ P I W +D +P+ + G + PT + D G Y C A N
Sbjct: 420 ISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479
Query: 2772 SVWT 2775
+ T
Sbjct: 480 HIGT 483
Score = 38.7 bits (86), Expect = 0.36
Identities = 28/131 (21%), Positives = 52/131 (39%), Gaps = 9/131 (6%)
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F V++ + +G + + P V WL VT + N + L +
Sbjct: 117 FREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANN--NLQIL 174
Query: 2874 DVTETESGLYTCRAW-SAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
++ +++ G+Y C A G +D I +V PA+ + + + GE++
Sbjct: 175 NINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVP-----PAISMPQKSFNATAERGEEMT 229
Query: 2933 ISFRTQGEPKP 2943
S R G P+P
Sbjct: 230 FSCRASGSPEP 240
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 76.6 bits (180), Expect = 1e-12
Identities = 53/174 (30%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A+EG L C V P+ TW R ++ +L+ +K + G L + N DS Y
Sbjct: 251 AIEGKDAVLECCVSGYPPPSFTWLRGEEVI--QLRSKKYSLLGGSNLLISNVTDDDSGMY 308
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
+C V +N IS SA L V +PP F + + ++ EC + G+P+P
Sbjct: 309 TCVVTYKNENISASAELTVL-------VPPWFLNHPSNLYAYESMDIEFECTVSGKPVPT 361
Query: 2725 ITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
+ W K+ D IPSD ++ G L I D G Y C AEN Q
Sbjct: 362 VNWMKNGDVVIPSD-----YFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQ 410
Score = 75.8 bits (178), Expect = 3e-12
Identities = 87/327 (26%), Positives = 127/327 (38%), Gaps = 44/327 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAG--RMTSQFNGFDCCLTIKDINIDDEGRY 3122
G+T L C V G+P+P + W KN ++ G R+ +G L I + D G Y
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSG---ALQISRLQPGDIGIY 210
Query: 3123 SCEATN-THGKASTYARLAVVTDRTVWEADAKLKRERSA-EVEGDYPPQFTMRLRDRRVQ 3180
C A N + A + +++D + L+R + +EG +D
Sbjct: 211 RCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEG----------KD---- 256
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
L C V G PPP +W + GEEV+ R KY L I+ DD G+Y
Sbjct: 257 ----AVLECCVSGYPPPSFTWLR-GEEVI-QLRSKKYSLLGGSNLLISNVTDDDSGMYTC 310
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ +S L V V P F LY +E ++ V P V
Sbjct: 311 VVTYKNENISASAELTV------LVPPWFLNHPSNLYA-YESMDIEFECTVSGKPVPTVN 363
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
W ++G + PS + G L + V D G Y C A NE G A TS ++ V
Sbjct: 364 WMKNGDVVIPSDYFQIV----GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV-- 417
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFI 3387
+P IP + P P P+ +
Sbjct: 418 ----PKPAIPSSSVLPSAPRDVVPVLV 440
Score = 70.9 bits (166), Expect = 7e-11
Identities = 85/332 (25%), Positives = 142/332 (42%), Gaps = 39/332 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKLKYRKK-LVDGLITLE-VLNAV 2657
+D + G V L CS S P + W ++G+ L + RK+ L +G + ++ +L++
Sbjct: 47 SDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSR 106
Query: 2658 --PSDSAEYSCTVE-NENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
D Y C ++G+I S +A + V A P+ F + ++L
Sbjct: 107 HHKPDEGLYQCEASLGDSGSIISRTAKVAV-----AGPL--RFLSQTESVTAFMGDTVLL 159
Query: 2714 ECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+C + G+P+P I W K+ + + P G + L G L I P D G Y C A N
Sbjct: 160 KCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGA--LQISRLQPGDIGIYRCSARNP 217
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ TG E++V + RQ +RP NV+ G L
Sbjct: 218 A--------SSRTGNEAEVR----ILSDPGLHRQLYFLQRP--SNVV----AIEGKDAVL 259
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P WLR G V ++ ++ + G L +S+VT+ +SG+YTC +
Sbjct: 260 ECCVSGYPPPSFTWLR-GEEVIQL--RSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKN 316
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
N+ +A +TV+ P P+ + DI
Sbjct: 317 ENISASAELTVLVPPWFLNHPSNLYAYESMDI 348
Score = 62.5 bits (145), Expect = 3e-08
Identities = 81/341 (23%), Positives = 129/341 (37%), Gaps = 36/341 (10%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
TA G V L C VI PT+ W +N L + +V L++ P D
Sbjct: 150 TAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGI 209
Query: 2664 YSCTVEN-ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C+ N + A +++ S F + + + + VLEC + G P
Sbjct: 210 YRCSARNPASSRTGNEAEVRIL-SDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPP 268
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
P TW + ++ I R + + L G L I N T +DSG YTC
Sbjct: 269 PSFTWLRGEEVIQL--RSKKYSLLGG-SNLLISNVTDDDSGMYTCVV------------- 312
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
T + +S +AE T + P F N ++ I + + G P
Sbjct: 313 --TYKNENIS---ASAELTVLV-------PPWFLNHPSNLYAYESMDIEFECTVSGKPVP 360
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
V W++ G +V + F G L + V +++ G Y C A + GN +A +
Sbjct: 361 TVNWMKNG----DVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLI 416
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
V +P+ R +L+S + +S+R E K
Sbjct: 417 VPKPAIPSSSVLPSAPRDVVPVLVS-SRFVRLSWRPPAEAK 456
Score = 61.7 bits (143), Expect = 5e-08
Identities = 64/262 (24%), Positives = 99/262 (37%), Gaps = 37/262 (14%)
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGD----RPEFVDILP 3057
+ P + L+ G+ +R + RN SS+T + V + D R + P
Sbjct: 191 VLPSGALQISRLQPGDIGIYRCSARNP----ASSRTGNEAEVRILSDPGLHRQLYFLQRP 246
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID 3117
+ + G+ A L C V G P P W++ G EV + + S G + L I ++ D
Sbjct: 247 SNVVAIEGKDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSN--LLISNVTDD 303
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D G Y+C T + S A L V+ PP F +
Sbjct: 304 DSGMYTCVVTYKNENISASAELTVLV-----------------------PPWFLNHPSNL 340
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
+ + C V G P P V+W K+G+ V+ + +Q L I D G
Sbjct: 341 YAYESMDIEFECTVSGKPVPTVNWMKNGDVVI---PSDYFQIVGGSNLRILGVVKSDEGF 397
Query: 3238 YEVTARNNSGAVSCHCGLVVDK 3259
Y+ A N +G L+V K
Sbjct: 398 YQCVAENEAGNAQTSAQLIVPK 419
Score = 60.9 bits (141), Expect = 8e-08
Identities = 63/268 (23%), Positives = 112/268 (41%), Gaps = 35/268 (13%)
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
R+A+V P +F + V L C+VIG P P + W K+ +++ ++
Sbjct: 130 RTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRV 189
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVS---CHCGLVVDKGIRAYVAPEFCCGLE 3274
L+I+ D G+Y +ARN + + + ++ D G+ + F
Sbjct: 190 VVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQL--YFLQRPS 247
Query: 3275 PLYKLHEGDELRISAVVEAYPSVGVTWYR--DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
+ + EG + + V YP TW R + ++LR + +++ G L ++ VT
Sbjct: 248 NVVAI-EGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL-----GGSNLLISNVT 301
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D+G+YTC + + S S ++ V+ VP P F+ P +
Sbjct: 302 DDDSGMYTCVVTYKNENISASAELTVL------------------VP----PWFLNHPSN 339
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWLRD 3420
A E + EC V G P P V W+++
Sbjct: 340 LYAYESMDIEFECTVSGKPVPTVNWMKN 367
Score = 53.2 bits (122), Expect = 2e-05
Identities = 48/180 (26%), Positives = 73/180 (40%), Gaps = 6/180 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F ++ A E ++ C+V PTV W +NG ++ ++ + G L +
Sbjct: 331 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQ---IVGGSNLRI 387
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAENELV 2712
L V SD Y C ENE G TSA L V P+ +S + P+ R + ++ +
Sbjct: 388 LGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVL-VSSRFVR 446
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLAIDNPTPEDSGTYTCKAEN 2771
L R + I F D R +A G +L + N PE T+ A N
Sbjct: 447 LSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYN 506
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 76.6 bits (180), Expect = 1e-12
Identities = 53/174 (30%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A+EG L C V P+ TW R ++ +L+ +K + G L + N DS Y
Sbjct: 251 AIEGKDAVLECCVSGYPPPSFTWLRGEEVI--QLRSKKYSLLGGSNLLISNVTDDDSGMY 308
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
+C V +N IS SA L V +PP F + + ++ EC + G+P+P
Sbjct: 309 TCVVTYKNENISASAELTVL-------VPPWFLNHPSNLYAYESMDIEFECTVSGKPVPT 361
Query: 2725 ITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
+ W K+ D IPSD ++ G L I D G Y C AEN Q
Sbjct: 362 VNWMKNGDVVIPSD-----YFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQ 410
Score = 75.8 bits (178), Expect = 3e-12
Identities = 87/327 (26%), Positives = 127/327 (38%), Gaps = 44/327 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAG--RMTSQFNGFDCCLTIKDINIDDEGRY 3122
G+T L C V G+P+P + W KN ++ G R+ +G L I + D G Y
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSG---ALQISRLQPGDIGIY 210
Query: 3123 SCEATN-THGKASTYARLAVVTDRTVWEADAKLKRERSA-EVEGDYPPQFTMRLRDRRVQ 3180
C A N + A + +++D + L+R + +EG +D
Sbjct: 211 RCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEG----------KD---- 256
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
L C V G PPP +W + GEEV+ R KY L I+ DD G+Y
Sbjct: 257 ----AVLECCVSGYPPPSFTWLR-GEEVI-QLRSKKYSLLGGSNLLISNVTDDDSGMYTC 310
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ +S L V V P F LY +E ++ V P V
Sbjct: 311 VVTYKNENISASAELTV------LVPPWFLNHPSNLYA-YESMDIEFECTVSGKPVPTVN 363
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
W ++G + PS + G L + V D G Y C A NE G A TS ++ V
Sbjct: 364 WMKNGDVVIPSDYFQIV----GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV-- 417
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFI 3387
+P IP + P P P+ +
Sbjct: 418 ----PKPAIPSSSVLPSAPRDVVPVLV 440
Score = 70.9 bits (166), Expect = 7e-11
Identities = 85/332 (25%), Positives = 142/332 (42%), Gaps = 39/332 (11%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKLKYRKK-LVDGLITLE-VLNAV 2657
+D + G V L CS S P + W ++G+ L + RK+ L +G + ++ +L++
Sbjct: 47 SDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSR 106
Query: 2658 --PSDSAEYSCTVE-NENGAI-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
D Y C ++G+I S +A + V A P+ F + ++L
Sbjct: 107 HHKPDEGLYQCEASLGDSGSIISRTAKVAV-----AGPL--RFLSQTESVTAFMGDTVLL 159
Query: 2714 ECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+C + G+P+P I W K+ + + P G + L G L I P D G Y C A N
Sbjct: 160 KCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGA--LQISRLQPGDIGIYRCSARNP 217
Query: 2773 VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGL 2832
+ TG E++V + RQ +RP NV+ G L
Sbjct: 218 A--------SSRTGNEAEVR----ILSDPGLHRQLYFLQRP--SNVV----AIEGKDAVL 259
Query: 2833 QVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAH 2891
+ + G P WLR G V ++ ++ + G L +S+VT+ +SG+YTC +
Sbjct: 260 ECCVSGYPPPSFTWLR-GEEVIQL--RSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKN 316
Query: 2892 GNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
N+ +A +TV+ P P+ + DI
Sbjct: 317 ENISASAELTVLVPPWFLNHPSNLYAYESMDI 348
Score = 62.5 bits (145), Expect = 3e-08
Identities = 81/341 (23%), Positives = 129/341 (37%), Gaps = 36/341 (10%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
TA G V L C VI PT+ W +N L + +V L++ P D
Sbjct: 150 TAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGI 209
Query: 2664 YSCTVEN-ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C+ N + A +++ S F + + + + VLEC + G P
Sbjct: 210 YRCSARNPASSRTGNEAEVRIL-SDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPP 268
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
P TW + ++ I R + + L G L I N T +DSG YTC
Sbjct: 269 PSFTWLRGEEVIQL--RSKKYSLLGG-SNLLISNVTDDDSGMYTCVV------------- 312
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
T + +S +AE T + P F N ++ I + + G P
Sbjct: 313 --TYKNENIS---ASAELTVLV-------PPWFLNHPSNLYAYESMDIEFECTVSGKPVP 360
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
V W++ G +V + F G L + V +++ G Y C A + GN +A +
Sbjct: 361 TVNWMKNG----DVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLI 416
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
V +P+ R +L+S + +S+R E K
Sbjct: 417 VPKPAIPSSSVLPSAPRDVVPVLVS-SRFVRLSWRPPAEAK 456
Score = 61.7 bits (143), Expect = 5e-08
Identities = 64/262 (24%), Positives = 99/262 (37%), Gaps = 37/262 (14%)
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGD----RPEFVDILP 3057
+ P + L+ G+ +R + RN SS+T + V + D R + P
Sbjct: 191 VLPSGALQISRLQPGDIGIYRCSARNP----ASSRTGNEAEVRILSDPGLHRQLYFLQRP 246
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID 3117
+ + G+ A L C V G P P W++ G EV + + S G + L I ++ D
Sbjct: 247 SNVVAIEGKDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSN--LLISNVTDD 303
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D G Y+C T + S A L V+ PP F +
Sbjct: 304 DSGMYTCVVTYKNENISASAELTVLV-----------------------PPWFLNHPSNL 340
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
+ + C V G P P V+W K+G+ V+ + +Q L I D G
Sbjct: 341 YAYESMDIEFECTVSGKPVPTVNWMKNGDVVI---PSDYFQIVGGSNLRILGVVKSDEGF 397
Query: 3238 YEVTARNNSGAVSCHCGLVVDK 3259
Y+ A N +G L+V K
Sbjct: 398 YQCVAENEAGNAQTSAQLIVPK 419
Score = 60.9 bits (141), Expect = 8e-08
Identities = 63/268 (23%), Positives = 112/268 (41%), Gaps = 35/268 (13%)
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
R+A+V P +F + V L C+VIG P P + W K+ +++ ++
Sbjct: 130 RTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRV 189
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVS---CHCGLVVDKGIRAYVAPEFCCGLE 3274
L+I+ D G+Y +ARN + + + ++ D G+ + F
Sbjct: 190 VVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQL--YFLQRPS 247
Query: 3275 PLYKLHEGDELRISAVVEAYPSVGVTWYR--DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
+ + EG + + V YP TW R + ++LR + +++ G L ++ VT
Sbjct: 248 NVVAI-EGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL-----GGSNLLISNVT 301
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D+G+YTC + + S S ++ V+ VP P F+ P +
Sbjct: 302 DDDSGMYTCVVTYKNENISASAELTVL------------------VP----PWFLNHPSN 339
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWLRD 3420
A E + EC V G P P V W+++
Sbjct: 340 LYAYESMDIEFECTVSGKPVPTVNWMKN 367
Score = 53.2 bits (122), Expect = 2e-05
Identities = 48/180 (26%), Positives = 73/180 (40%), Gaps = 6/180 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F ++ A E ++ C+V PTV W +NG ++ ++ + G L +
Sbjct: 331 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQ---IVGGSNLRI 387
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAENELV 2712
L V SD Y C ENE G TSA L V P+ +S + P+ R + ++ +
Sbjct: 388 LGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVL-VSSRFVR 446
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLAIDNPTPEDSGTYTCKAEN 2771
L R + I F D R +A G +L + N PE T+ A N
Sbjct: 447 LSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYN 506
>DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosphatase
receptor type F protein.
Length = 262
Score = 76.6 bits (180), Expect = 1e-12
Identities = 60/224 (26%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGGINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V + + +
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLR 188
Query: 3222 FHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAY 3264
L+I + D G YE A N++G S L V +G+ A+
Sbjct: 189 SGALQIESSEESDQGKYECVATNSAGTRYSAPANLYV-RGLAAW 231
Score = 74.5 bits (175), Expect = 6e-12
Identities = 53/187 (28%), Positives = 77/187 (41%), Gaps = 7/187 (3%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGGINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
+ C G P P+I+WFKD + P+ + L G L I++ D G Y C
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA--LQIESSEESDQGKYECV 208
Query: 2769 AENSVWT 2775
A NS T
Sbjct: 209 ATNSAGT 215
Score = 55.6 bits (128), Expect = 3e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGGINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 55.2 bits (127), Expect = 4e-06
Identities = 53/208 (25%), Positives = 86/208 (41%), Gaps = 12/208 (5%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGGINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQIELALAAVTT 3333
K+ E + P ++W++D + + P S I L R G +++ + +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-RSGALQIESSEES- 200
Query: 3334 RDAGVYTCTASNEVG-RASTSGKVEVIG 3360
D G Y C A+N G R S + V G
Sbjct: 201 -DQGKYECVATNSAGTRYSAPANLYVRG 227
Score = 42.3 bits (95), Expect = 0.030
Identities = 59/203 (29%), Positives = 90/203 (44%), Gaps = 27/203 (13%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---GINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNGFDCC 3108
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---A 191
Query: 3109 LTIKDINIDDEGRYSCEATNTHG 3131
L I+ D+G+Y C ATN+ G
Sbjct: 192 LQIESSEESDQGKYECVATNSAG 214
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 76.6 bits (180), Expect = 1e-12
Identities = 58/171 (33%), Positives = 82/171 (47%), Gaps = 14/171 (8%)
Query: 3189 CQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGA 3248
C+ G P P W K+GE ++ R++ Q EQ TL I NL D G+Y+ A N G
Sbjct: 9 CKANGRPKPTYKWLKNGEPLL---TRDRIQIEQ-GTLNITIVNLSDAGMYQCLAENKHGV 64
Query: 3249 VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE-GDELRISAVVEAYPSVGVTWYRDGVR 3307
+ + L V V P+F L L + G E+ I +A P TW +
Sbjct: 65 IFSNAELSV-----IAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDI 119
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L+ + R +T+ DG L + VT DAG YTC A+N G AS++G + V
Sbjct: 120 LKENER--ITISEDGN--LRIINVTKSDAGSYTCIATNHFGTASSTGNLVV 166
Score = 67.7 bits (158), Expect = 7e-10
Identities = 51/167 (30%), Positives = 76/167 (45%), Gaps = 16/167 (9%)
Query: 2615 CSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGA 2674
C PT W +NG L + R ++ G + + ++N SD+ Y C EN++G
Sbjct: 9 CKANGRPKPTYKWLKNGEPL--LTRDRIQIEQGTLNITIVNL--SDAGMYQCLAENKHGV 64
Query: 2675 ISTSANLKVYPSFEASPIPPTFTRSI--RDTFHLAENELVLECRIRGQPLPKITWFKDDK 2732
I ++A L V + P F+R++ R T E+V+EC+ + P P TW K
Sbjct: 65 IFSNAELSVI------AVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRD 118
Query: 2733 QIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
+ + R DG L I N T D+G+YTC A N T T
Sbjct: 119 ILKENERIT--ISEDG--NLRIINVTKSDAGSYTCIATNHFGTASST 161
Score = 56.0 bits (129), Expect = 2e-06
Identities = 70/293 (23%), Positives = 107/293 (36%), Gaps = 39/293 (13%)
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
C G+P P W+KNG + Q L I +N+ D G Y C A N HG
Sbjct: 9 CKANGRPKPTYKWLKNGEPLLTRDRIQIEQGT-----LNITIVNLSDAGMYQCLAENKHG 63
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
+ A L+V+ + + LKR +V G+ V + C+
Sbjct: 64 VIFSNAELSVIAVGPDF-SRTLLKRVTLVKVGGE-------------------VVIECKP 103
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSC 3251
SP P +W K G +++ + R ++ L I D G Y A N+ G S
Sbjct: 104 KASPKPVYTW-KKGRDILKENERITISED--GNLRIINVTKSDAGSYTCIATNHFGTASS 160
Query: 3252 HCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV--TWYRDGVRLR 3309
LVV R V P + G+ + + V S+ + TW +G +
Sbjct: 161 TGNLVVKDPTRVMVPPS-------SMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 213
Query: 3310 PSRRA--IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
R + D +L + + + AG Y C V R S + + V G
Sbjct: 214 FDRDGDHFERVGGDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRG 266
Score = 49.6 bits (113), Expect = 2e-04
Identities = 48/199 (24%), Positives = 84/199 (42%), Gaps = 30/199 (15%)
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
E + EC+ G+P P W K+ + + + R Q + G + I N + D+G Y C
Sbjct: 2 EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQ---IEQGTLNITIVNLS--DAGMYQC 56
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
AEN H V F+ E V +T + R +L V G
Sbjct: 57 LAENK-------HGVIFSNAELSVIAVGPDFSRTLLKRVTL---------------VKVG 94
Query: 2828 GTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
G + ++ + + P V ++GR + + N R+ + + L + +VT++++G YTC A
Sbjct: 95 GEVVIECKPKASPKPVYTWKKGRDILK--ENERITISED-GNLRIINVTKSDAGSYTCIA 151
Query: 2888 WSAHGNVDMNAAITVVQPS 2906
+ G + V P+
Sbjct: 152 TNHFGTASSTGNLVVKDPT 170
Score = 45.2 bits (102), Expect = 0.004
Identities = 56/213 (26%), Positives = 83/213 (38%), Gaps = 18/213 (8%)
Query: 2594 PVFSTFLTDR-TAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
P FS L R T V+ G V + C +S P TW + +L + DG L
Sbjct: 78 PDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITIS-EDG--NL 134
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
++N SD+ Y+C N G S++ NL V +PP S D +
Sbjct: 135 RIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVM-VPP----SSMDV--TVGESI 187
Query: 2712 VLECRIRGQPLPKI--TWFKDDKQI--PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
VL C++ I TW + I DG + D L I N + +G Y C
Sbjct: 188 VLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGDSAGDLMIRNIQLKHAGKYVC 247
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEK 2800
+ SV D+++ + R P VT ++
Sbjct: 248 MVQTSV--DRLSAAADLIVRGPPGPPEAVTIDE 278
Score = 44.4 bits (100), Expect = 0.007
Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 3021 FRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL-AGETANLTCSVKGKPV 3079
++ N++G S+ S I VG P+F L ++ ++ G + C K P
Sbjct: 54 YQCLAENKHGVIFSNAELSVIAVG-----PDFSRTLLKRVTLVKVGGEVVIECKPKASPK 108
Query: 3080 PGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARL 3139
P W K G ++ +E R+T +G L I ++ D G Y+C ATN G AS+ L
Sbjct: 109 PVYTW-KKGRDILKENERITISEDGN---LRIINVTKSDAGSYTCIATNHFGTASSTGNL 164
Query: 3140 AVVTDRT 3146
VV D T
Sbjct: 165 -VVKDPT 170
Score = 40.3 bits (90), Expect = 0.12
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 10/100 (10%)
Query: 2844 EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+WL+ G + R+ +EQG TL ++ V +++G+Y C A + HG + NA ++V+
Sbjct: 20 KWLKNGEPLLT---RDRIQIEQG--TLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI 74
Query: 2904 QPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
D ++ ++ L+ VG ++ I + + PKP
Sbjct: 75 AVGP-DFSRTLL----KRVTLVKVGGEVVIECKPKASPKP 109
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens cDNA
FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 76.2 bits (179), Expect = 2e-12
Identities = 78/294 (26%), Positives = 121/294 (41%), Gaps = 42/294 (14%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
V LTC PTV+W + G L + + G LE+ A+P + Y+C+ N
Sbjct: 5 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG--ALEIGQALPIHAGRYTCSARN 62
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKD 2730
G A+ V+ + +ASP+ +R +AE E++L C G P P ITW K+
Sbjct: 63 SAGV----AHKHVFLTVQASPVVKPLPSVVR---AVAEEEVLLPCEASGIPRPTITWQKE 115
Query: 2731 DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQ 2790
+ + Q L G R+A + +PED+G Y C A+NS +
Sbjct: 116 GLNVATGVSTQV--LPGGQLRIA--HASPEDAGNYLCIAKNSAGS--------------- 156
Query: 2791 VSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREG 2849
KTR+ Q P N L D G L + RG P + W ++G
Sbjct: 157 ------AMGKTRLVVQV----PPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDG 206
Query: 2850 RSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+ V+ F Q L + ++ ++G YTC A +A G +T++
Sbjct: 207 QPVSGAEGK---FTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL 257
Score = 74.1 bits (174), Expect = 8e-12
Identities = 51/169 (30%), Positives = 72/169 (42%), Gaps = 13/169 (7%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
AV V L C PT+TW + G+ + + + L G L + +A P D+ Y
Sbjct: 90 AVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS-TQVLPGG--QLRIAHASPEDAGNY 146
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
C +N G+ L V +PP + D + L C+ RG P P
Sbjct: 147 LCIAKNSAGSAMGKTRLVVQ-------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPN 199
Query: 2725 ITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
ITW KD + P G F + L + N +D+GTYTC AEN+V
Sbjct: 200 ITWDKDGQ--PVSGAEGKFTIQPS-GELLVKNLEGQDAGTYTCTAENAV 245
Score = 70.9 bits (166), Expect = 7e-11
Identities = 92/348 (26%), Positives = 127/348 (36%), Gaps = 61/348 (17%)
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
LTC G P P V W K G ++ +G L I GRY+C A N+
Sbjct: 7 LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNS 63
Query: 3130 HGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTC 3189
G A + L V +A +K S R A V L C
Sbjct: 64 AGVAHKHVFLTV-------QASPVVKPLPSVV----------------RAVAEEEVLLPC 100
Query: 3190 QVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAV 3249
+ G P P ++W K+G V Q L IA + +D G Y A+N++G+
Sbjct: 101 EASGIPRPTITWQKEGLNVATGVSTQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSA 157
Query: 3250 SCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLR 3309
LVV V P GL L EG + P +TW +DG +
Sbjct: 158 MGKTRLVVQ------VPPVIENGLPDL-STTEGSHAFLPCKARGSPEPNITWDKDGQPVS 210
Query: 3310 PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRI 3369
+ T+ G EL + + +DAG YTCTA N VGRA + ++
Sbjct: 211 GAEGKF-TIQPSG--ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL---------- 257
Query: 3370 PPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
V+ P+F P R GD + + C G P P + W
Sbjct: 258 ---VL---------PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGW 293
Score = 64.5 bits (150), Expect = 6e-09
Identities = 63/237 (26%), Positives = 95/237 (40%), Gaps = 35/237 (14%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
PV LTC G P P VSW K G ++ R + Y+ LEI G Y +AR
Sbjct: 4 PVVLTCHSTGIPAPTVSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTCSAR 61
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N++G H L V V P L + + +E+ + P +TW +
Sbjct: 62 NSAGVAHKHVFLTVQAS--PVVKP-----LPSVVRAVAEEEVLLPCEASGIPRPTITWQK 114
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+G+ + + T G +L +A + DAG Y C A N G S GK ++
Sbjct: 115 EGLNV---ATGVSTQVLPGG-QLRIAHASPEDAGNYLCIAKNSAG--SAMGKTRLV---- 164
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
++PP VI +P EG + C+ G P+P++ W +D
Sbjct: 165 ---VQVPP-VIENGLP------------DLSTTEGSHAFLPCKARGSPEPNITWDKD 205
Score = 58.4 bits (135), Expect = 4e-07
Identities = 41/145 (28%), Positives = 58/145 (40%), Gaps = 9/145 (6%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV L D + EGS L C S +P +TW ++G + K + L V
Sbjct: 169 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG--AEGKFTIQPSGELLV 226
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVL 2713
N D+ Y+CT EN G +L + + P FT D + L L
Sbjct: 227 KNLEGQDAGTYTCTAENAVGRARRRVHLTIL-------VLPVFTTLPGDRSLRLGDRLWL 279
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDG 2738
C RG P P+I W +D+ + G
Sbjct: 280 RCAARGSPTPRIGWTVNDRPVTGLG 304
Score = 54.0 bits (124), Expect = 9e-06
Identities = 64/246 (26%), Positives = 82/246 (33%), Gaps = 36/246 (14%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP ++ +A E L C G P P + W K G V G T G L I +
Sbjct: 84 LPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNV--ATGVSTQVLPGGQ--LRIAHAS 139
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLR 3175
+D G Y C A N+ G A RL V PP L
Sbjct: 140 PEDAGNYLCIAKNSAGSAMGKTRLVV-----------------------QVPPVIENGLP 176
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
D L C+ GSP P ++W KDG+ V K+ + L + D
Sbjct: 177 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV--SGAEGKFTIQPSGELLVKNLEGQDA 234
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y TA N G L + V P F L L GD L + P
Sbjct: 235 GTYTCTAENAVGRARRRVHLTI------LVLPVFTT-LPGDRSLRLGDRLWLRCAARGSP 287
Query: 3296 SVGVTW 3301
+ + W
Sbjct: 288 TPRIGW 293
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 75.8 bits (178), Expect = 3e-12
Identities = 87/376 (23%), Positives = 147/376 (39%), Gaps = 52/376 (13%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF-D 3106
++P V I A A L C G P+P + W + ++ + S+ +
Sbjct: 1646 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 1705
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDY 3166
L+I+ + I D G+Y C A+N G + L+VV+ Y
Sbjct: 1706 GTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVS----------------------Y 1743
Query: 3167 PPQFT-MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD--EQFH 3223
PP+ R ++ V + V L C+ G P P V+W + VV + + Q
Sbjct: 1744 PPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDG 1803
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE-G 3282
TL + ++ D G Y+ A N G S L+V I+ AP + G
Sbjct: 1804 TLVLHNLSIYDRGFYKCVASNPGGQDS----LLVK--IQVIAAPPVILEQRRQVIVGTWG 1857
Query: 3283 DELRISAVVEAYPSVGVTW-YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+ L++ + P V W DG ++P + L L + + + D G Y C
Sbjct: 1858 ESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYEC 1917
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G + +V ++ T E R V SP + + + + +E GD +
Sbjct: 1918 IATSSTG---SERRVVML----TMEER----VTSPRIEAASQ-------KRTEVNFGDKL 1959
Query: 3402 IIECEVVGDPKPDVYW 3417
++ C G+PKP + W
Sbjct: 1960 LLNCSATGEPKPQIMW 1975
Score = 68.9 bits (161), Expect = 3e-10
Identities = 73/309 (23%), Positives = 127/309 (41%), Gaps = 40/309 (12%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQ-FNGFDCC 3108
P ++ ++ + +G T L C +G+P P V W+ V E+ + + Q D
Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT 1804
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L + +++I D G Y C A+N G+ S ++ V+ A + +R + G +
Sbjct: 1805 LVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIA------APPVILEQRRQVIVGTWGE 1858
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSW-YKDGEEV-VYDKRRNKYQDEQFHTLE 3226
++L C G+P P V W DG EV +K TL
Sbjct: 1859 S---------------LKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLY 1903
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I D G YE A +++G+ L +++ + +P + +++ GD+L
Sbjct: 1904 IRNLASSDRGTYECIATSSTGSERRVVMLTMEERV---TSPRIEAASQKRTEVNFGDKLL 1960
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-------ELALAAVTTRDAGVY 3339
++ P + W RL PS+ + R G L + +VT +D+GVY
Sbjct: 1961 LNCSATGEPKPQIMW-----RL-PSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVY 2014
Query: 3340 TCTASNEVG 3348
C A N++G
Sbjct: 2015 LCVARNKMG 2023
Score = 65.3 bits (152), Expect = 4e-09
Identities = 88/373 (23%), Positives = 151/373 (40%), Gaps = 64/373 (17%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVW------MKNGHEVEEEAGRMTSQFNGFDC-CLTIKD 3113
++L G+ + C G PVP + W M N +++G T ++ F+ L
Sbjct: 2049 QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNK 2108
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
+ + +EG Y+C A NT GK L V+T A ++++
Sbjct: 2109 VGVAEEGDYTCYAQNTLGKDEMKVHLTVIT------AAPRIRQSNKT------------- 2149
Query: 3174 LRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLD 3233
++R++A L C+V G P PK+ W +++ ++Y +L I L
Sbjct: 2150 --NKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMI-SFSIDRYTFHANGSLTINKVKLL 2206
Query: 3234 DGGVYEVTARNNSGAVSCHCGL-VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRIS---- 3288
D G Y ARN SG + L VV K P GL + + +R S
Sbjct: 2207 DSGEYVCVARNPSGDDTKMYKLDVVSK-------PPLINGLYTNRTVIKATAVRHSKKHF 2259
Query: 3289 -AVVEAYPSVGVTWYR-DGVRL-RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
E PS V W D + L P + +T+ ++G +E + V D+ + C A N
Sbjct: 2260 DCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLE--IRNVRLSDSADFICVARN 2317
Query: 3346 EVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIEC 3405
E G + ++EV+ + P P++++ + A+ G + + C
Sbjct: 2318 EGGESVLVVQLEVL--EMLRRPTFRN-------PFNEKIV---------AQLGKSTALNC 2359
Query: 3406 EVVGDPKPDVYWL 3418
V G+P P++ W+
Sbjct: 2360 SVDGNPPPEIIWI 2372
Score = 64.1 bits (149), Expect = 8e-09
Identities = 84/360 (23%), Positives = 137/360 (38%), Gaps = 48/360 (13%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
+I AG+TA L C V G P P + W+ ++ + R T NG LTI + + D
Sbjct: 2152 RIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG---SLTINKVKLLDS 2208
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C A N G + +L VV+ + + G Y + ++ R
Sbjct: 2209 GEYVCVARNPSGDDTKMYKLDVVS--------------KPPLINGLYTNRTVIKATAVRH 2254
Query: 3180 QATYPVRLTCQVIGSPPPKVSW-YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ C+ G+P P+V W D + ++ + TLEI L D +
Sbjct: 2255 SKKH---FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADF 2311
Query: 3239 EVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVG 3298
ARN G L V + +R P F G ++ V+ P
Sbjct: 2312 ICVARNEGGESVLVVQLEVLEMLR---RPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPE 2368
Query: 3299 VTW-YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
+ W +G R ++ L ++ T DAG Y C A N+VG K+
Sbjct: 2369 IIWILPNGTRFSNGPQSYQYLIASNG-SFIISKTTREDAGKYRCAARNKVGYIE---KLV 2424
Query: 3358 VIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
++ Q PV+++ Y+ P + + G+++ + C G PKP++ W
Sbjct: 2425 ILEIGQ------KPVILT----YA--------PGTVKGISGESLSLHCVSDGIPKPNIKW 2466
Score = 64.1 bits (149), Expect = 8e-09
Identities = 56/210 (26%), Positives = 88/210 (41%), Gaps = 33/210 (15%)
Query: 3047 GDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEA--GRMTSQFN 3103
G +P + PG +K ++GE+ +L C G P P + W M +G+ V+ G+ N
Sbjct: 2429 GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDN 2488
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
G L IK+ D G Y C+A N+ G + +V
Sbjct: 2489 G---TLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVA-------------------- 2525
Query: 3164 GDYPPQFTMRLRDRRVQAT-YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNK-YQDEQ 3221
YPP+ T R V T +L C +G P P+++W ++ + + + EQ
Sbjct: 2526 --YPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQ 2583
Query: 3222 FH---TLEIAPTNLDDGGVYEVTARNNSGA 3248
H TL I D G+Y+ TA+N G+
Sbjct: 2584 LHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 2613
Score = 63.3 bits (147), Expect = 1e-08
Identities = 84/354 (23%), Positives = 129/354 (36%), Gaps = 60/354 (16%)
Query: 3072 CSVKGKPVPGVVWMKNGH---EVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
C +G P P V+W+ + R+T NG L I+++ + D + C A N
Sbjct: 2261 CRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG---TLEIRNVRLSDSADFICVARN 2317
Query: 3129 THGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV-QATYPVRL 3187
G++ +L V+ L+R P F ++ V Q L
Sbjct: 2318 EGGESVLVVQLEVLE---------MLRR-----------PTFRNPFNEKIVAQLGKSTAL 2357
Query: 3188 TCQVIGSPPPKVSW-YKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
C V G+PPP++ W +G + +Y + I+ T +D G Y ARN
Sbjct: 2358 NCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKV 2417
Query: 3247 GAVSCHCGLVV-DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG 3305
G + L + K + AP G+ G+ L + V + P + W
Sbjct: 2418 GYIEKLVILEIGQKPVILTYAPGTVKGI-------SGESLSLHCVSDGIPKPNIKWTMPS 2470
Query: 3306 --VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
V RP L +G L + T D G Y C A N VG + V ++
Sbjct: 2471 GYVVDRPQINGKYILHDNG--TLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVA--- 2525
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
PP + + R PRS R G + C +G PKP++ W
Sbjct: 2526 -----YPPRITN------------RPPRSIVTRTGAAFQLHCVALGVPKPEITW 2562
Score = 61.7 bits (143), Expect = 5e-08
Identities = 93/383 (24%), Positives = 152/383 (39%), Gaps = 46/383 (12%)
Query: 2585 TLSRNSTRKP-VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKK 2643
+LSR KP + T S L C + + PT+ W R LD + +
Sbjct: 1639 SLSRYIFEKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNS 1698
Query: 2644 LVDGLI--TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
V L TL + D +Y C+ N G L V S P R +
Sbjct: 1699 RVQVLPNGTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSV-----VSYPPRILERRTK 1753
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPT 2758
+ + + + L+CR G+P P +TW ++ + S+ G QA DG L + N +
Sbjct: 1754 EITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT--LVLHNLS 1811
Query: 2759 PEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
D G Y C A N D + V V+ A LE RR V
Sbjct: 1812 IYDRGFYKCVASNPGGQDSLL-----------VKIQVIAAPPV-----ILEQRR----QV 1851
Query: 2819 LTDYQVARGGTIGLQVEIRGCP-TRVEW-LREGRSVTEV-YRNARVFVEQGLYTLALSDV 2875
+ G ++ L +G P V W L +G V + + N+++F+ TL + ++
Sbjct: 1852 IVG---TWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSN-GTLYIRNL 1907
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISF 2935
++ G Y C A S+ G+ + ++ + P I +K ++ G+ + ++
Sbjct: 1908 ASSDRGTYECIATSSTGS---ERRVVMLTMEERVTSPR-IEAASQKRTEVNFGDKLLLNC 1963
Query: 2936 RTQGEPKPKAVPERIPGEPCVVD 2958
GEPKP+ + R+P + VVD
Sbjct: 1964 SATGEPKPQ-IMWRLPSK-AVVD 1984
Score = 61.7 bits (143), Expect = 5e-08
Identities = 60/239 (25%), Positives = 97/239 (40%), Gaps = 36/239 (15%)
Query: 3187 LTCQVIGSPPPKVSWYK--DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C+ +G+P P + W + G ++ K+ ++ Q TL I + D G Y +A N
Sbjct: 1668 LPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASN 1727
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
G H L V P +H G + + E PS VTW
Sbjct: 1728 LFGTDHLHVTLSV-----VSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILA 1782
Query: 3305 GVRL-----RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ + SR+A++T+D L L ++ D G Y C ASN G+ S K++VI
Sbjct: 1783 NQTVVSESSQGSRQAVVTVDGT----LVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVI 1838
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
PPV++ ++ + G+++ + C G P+P VYW+
Sbjct: 1839 AA--------PPVILE------------QRRQVIVGTWGESLKLPCTAKGTPQPSVYWV 1877
Score = 61.7 bits (143), Expect = 5e-08
Identities = 49/189 (25%), Positives = 73/189 (38%), Gaps = 9/189 (4%)
Query: 2591 TRKPVFSTFLTDRTAVEGSRVK-----LTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL- 2644
++ P+ + T+RT ++ + V+ C + P V W + Y ++
Sbjct: 2232 SKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRIT 2291
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
V TLE+ N SDSA++ C NE G L+V F I
Sbjct: 2292 VHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKI--VA 2349
Query: 2705 HLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
L ++ L C + G P P+I W + S+G YL I T ED+G
Sbjct: 2350 QLGKST-ALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGK 2408
Query: 2765 YTCKAENSV 2773
Y C A N V
Sbjct: 2409 YRCAARNKV 2417
Score = 60.1 bits (139), Expect = 1e-07
Identities = 88/349 (25%), Positives = 133/349 (38%), Gaps = 43/349 (12%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWY--RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
T GS V+L C PTVTW V+ ++ R+ +V TL + N D
Sbjct: 1756 TVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDR 1815
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQ 2720
Y C N G S ++V + PP R E L L C +G
Sbjct: 1816 GFYKCVASNPGGQDSLLVKIQVIAA------PPVILEQRRQVIVGTWGESLKLPCTAKGT 1869
Query: 2721 PLPKITWFKDDKQIPSDGRY---QAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
P P + W D ++ + F ++G L I N D GTY C A +S +++
Sbjct: 1870 PQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGT--LYIRNLASSDRGTYECIATSSTGSER 1927
Query: 2778 ITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIR 2837
V T E SP + A + R +FG+ L + G Q+ R
Sbjct: 1928 --RVVMLTMEERVTSPRIEAASQKR--------TEVNFGDKLL-LNCSATGEPKPQIMWR 1976
Query: 2838 GCPTR--VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
P++ V+ S VY N +F+ VTE +SG+Y C A + G+ D
Sbjct: 1977 -LPSKAVVDQQHRVGSWIHVYPNGSLFI---------GSVTEKDSGVYLCVARNKMGD-D 2025
Query: 2896 MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ ++ L KPA I + + G+D + + G P P+
Sbjct: 2026 L-----ILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPE 2069
Score = 56.8 bits (131), Expect = 1e-06
Identities = 46/190 (24%), Positives = 69/190 (36%), Gaps = 8/190 (4%)
Query: 2592 RKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLI 2649
R+P F ++ + G L CSV + P + W NG N + + L+
Sbjct: 2335 RRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 2394
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
+ + D+ +Y C N+ G I L++ P T + ++
Sbjct: 2395 SFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK------PVILTYAPGTVKGISGE 2448
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
L L C G P P I W + + Y+ L I T D G Y CKA
Sbjct: 2449 SLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKA 2508
Query: 2770 ENSVWTDQIT 2779
+NSV IT
Sbjct: 2509 QNSVGHTLIT 2518
Score = 54.4 bits (125), Expect = 7e-06
Identities = 51/198 (25%), Positives = 78/198 (39%), Gaps = 14/198 (7%)
Query: 2592 RKPVFSTFLTDRT-AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLI 2649
+KPV T+ + G + L C P + W +G ++D K ++
Sbjct: 2430 QKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNG 2489
Query: 2650 TLEVLNAVPSDSAEYSCTVENENG--AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
TL + A D Y C +N G I+ + YP + PP RSI A
Sbjct: 2490 TLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPP-RITNRPP---RSIVTRTGAA 2545
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVC---RLAIDNPTPEDSGT 2764
L C G P P+ITW D + S + + ++ + L I NP DSG
Sbjct: 2546 ---FQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGI 2602
Query: 2765 YTCKAENSVWTDQITHFV 2782
Y C A+N + +D ++
Sbjct: 2603 YKCTAKNPLGSDYAATYI 2620
Score = 45.6 bits (103), Expect = 0.003
Identities = 75/317 (23%), Positives = 110/317 (34%), Gaps = 35/317 (11%)
Query: 3049 RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEAGRMTSQFN-GFD 3106
RP F + ++ G++ L CSV G P P ++W + NG G + Q+ +
Sbjct: 2336 RPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSN--GPQSYQYLIASN 2393
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDY 3166
I +D G+Y C A N G Y V+ + G
Sbjct: 2394 GSFIISKTTREDAGKYRCAARNKVG----YIEKLVILEI------------------GQK 2431
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTL 3225
P T + + + L C G P P + W VV + N KY TL
Sbjct: 2432 PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTL 2491
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I D G Y A+N+ G H + V I AY P G
Sbjct: 2492 VIKEATAYDRGNYICKAQNSVG----HTLITVPVMIVAY-PPRITNRPPRSIVTRTGAAF 2546
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDG---QIELALAAVTTRDAGVYTCT 3342
++ V P +TW L + T + Q L + T D+G+Y CT
Sbjct: 2547 QLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCT 2606
Query: 3343 ASNEVGRASTSGKVEVI 3359
A N +G + ++VI
Sbjct: 2607 AKNPLGSDYAATYIQVI 2623
Score = 44.8 bits (101), Expect = 0.006
Identities = 46/222 (20%), Positives = 88/222 (39%), Gaps = 19/222 (8%)
Query: 2603 RTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKL-------KYRKKLVDGLITLEVL 2654
+ + G ++ C S P ++W +G +++N + + R+ + TL
Sbjct: 2048 KQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFN 2107
Query: 2655 NAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL-AENELVL 2713
++ +Y+C +N G +L V + P +S + + A + VL
Sbjct: 2108 KVGVAEEGDYTCYAQNTLGKDEMKVHLTVITA------APRIRQSNKTNKRIKAGDTAVL 2161
Query: 2714 ECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
+C + G P PKI W + S + + A+G L I+ DSG Y C A N
Sbjct: 2162 DCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG--SLTINKVKLLDSGEYVCVARNPS 2219
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHF 2815
D + ++ + + N + +T I ++ + HF
Sbjct: 2220 GDDTKMYKLDVVSKPPLI--NGLYTNRTVIKATAVRHSKKHF 2259
Score = 38.3 bits (85), Expect = 0.48
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 9/95 (9%)
Query: 2817 NVLTDYQVARGGTIGLQVEIRGCPT-RVEW-LREGRSVTEVY--RNARVFVEQ-GLYTLA 2871
N ++ V GGT+GL +G PT V+W L +G V Y + R+ +++ G L
Sbjct: 480 NTKLEHTVLVGGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQ 539
Query: 2872 LSDVTETESGLYTCRAWSAHGNVD-MNAAITVVQP 2905
++D +T G+Y C + S + + D + ITVV+P
Sbjct: 540 MADSFDT--GVYHCIS-SNYDDADILTYRITVVEP 571
Score = 38.3 bits (85), Expect = 0.48
Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 13/104 (12%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET +L C G P + W+ G+ V ++ R N + L I + D+G
Sbjct: 585 VFIGETLDLPCHSTGIPDASISWVIPGNNVLYQSSRDKKVLN--NGTLRILQVTPKDQGY 642
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
Y C A N G D +++ K+K +R E +G+
Sbjct: 643 YRCVAANPSG-----------VDFLIFQVSVKMKGQRPLEHDGE 675
Score = 37.9 bits (84), Expect = 0.64
Identities = 44/169 (26%), Positives = 66/169 (39%), Gaps = 14/169 (8%)
Query: 3185 VRLTCQVIGSPPPKVSWY-KDGEEV--VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVT 3241
V L C G P P V W DG +V Y + ++ LE+ + D GVY
Sbjct: 493 VGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVYHCI 552
Query: 3242 ARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ N A + + VV+ + AY G+ + + G+ L + P ++
Sbjct: 553 SSNYDDADILTYRITVVEPLVEAYQEN----GIH--HTVFIGETLDLPCHSTGIPDASIS 606
Query: 3301 WYRDGVR-LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
W G L S R L+ L + VT +D G Y C A+N G
Sbjct: 607 WVIPGNNVLYQSSRDKKVLNNG---TLRILQVTPKDQGYYRCVAANPSG 652
Score = 36.7 bits (81), Expect = 1.5
Identities = 43/179 (24%), Positives = 63/179 (35%), Gaps = 12/179 (6%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYR---NGVLLDNKLKYRKKLVDGLITLEVLNAVP 2658
+ T + G V L C P V W + V + + L+D LE+ A
Sbjct: 484 EHTVLVGGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADS 543
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS-IRDTFHLAENELVLECRI 2717
D+ Y C N + A++ Y P+ + + I T + E L L C
Sbjct: 544 FDTGVYHCISSNYD-----DADILTYRITVVEPLVEAYQENGIHHTVFIGET-LDLPCHS 597
Query: 2718 RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G P I+W + L +G R+ TP+D G Y C A N D
Sbjct: 598 TGIPDASISWVIPGNNVLYQSSRDKKVLNNGTLRIL--QVTPKDQGYYRCVAANPSGVD 654
>AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens cDNA
FLJ46283 fis, clone TESTI4031173. ).
Length = 632
Score = 75.8 bits (178), Expect = 3e-12
Identities = 87/376 (23%), Positives = 147/376 (39%), Gaps = 52/376 (13%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGF-D 3106
++P V I A A L C G P+P + W + ++ + S+ +
Sbjct: 273 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 332
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDY 3166
L+I+ + I D G+Y C A+N G + L+VV+ Y
Sbjct: 333 GTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVS----------------------Y 370
Query: 3167 PPQFT-MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD--EQFH 3223
PP+ R ++ V + V L C+ G P P V+W + VV + + Q
Sbjct: 371 PPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDG 430
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHE-G 3282
TL + ++ D G Y+ A N G S L+V I+ AP + G
Sbjct: 431 TLVLHNLSIYDRGFYKCVASNPGGQDS----LLVK--IQVIAAPPVILEQRRQVIVGTWG 484
Query: 3283 DELRISAVVEAYPSVGVTW-YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+ L++ + P V W DG ++P + L L + + + D G Y C
Sbjct: 485 ESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYEC 544
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTV 3401
A++ G + +V ++ T E R V SP + + + + +E GD +
Sbjct: 545 IATSSTG---SERRVVML----TMEER----VTSPRIEAASQ-------KRTEVNFGDKL 586
Query: 3402 IIECEVVGDPKPDVYW 3417
++ C G+PKP + W
Sbjct: 587 LLNCSATGEPKPQIMW 602
Score = 61.7 bits (143), Expect = 5e-08
Identities = 93/383 (24%), Positives = 152/383 (39%), Gaps = 46/383 (12%)
Query: 2585 TLSRNSTRKP-VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKK 2643
+LSR KP + T S L C + + PT+ W R LD + +
Sbjct: 266 SLSRYIFEKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNS 325
Query: 2644 LVDGLI--TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIR 2701
V L TL + D +Y C+ N G L V S P R +
Sbjct: 326 RVQVLPNGTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSV-----VSYPPRILERRTK 380
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSD---GRYQAFYLADGVCRLAIDNPT 2758
+ + + + L+CR G+P P +TW ++ + S+ G QA DG L + N +
Sbjct: 381 EITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT--LVLHNLS 438
Query: 2759 PEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNV 2818
D G Y C A N D + V V+ A LE RR V
Sbjct: 439 IYDRGFYKCVASNPGGQDSLL-----------VKIQVIAAPPV-----ILEQRR----QV 478
Query: 2819 LTDYQVARGGTIGLQVEIRGCP-TRVEW-LREGRSVTEV-YRNARVFVEQGLYTLALSDV 2875
+ G ++ L +G P V W L +G V + + N+++F+ TL + ++
Sbjct: 479 IVG---TWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSN-GTLYIRNL 534
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISF 2935
++ G Y C A S+ G+ + ++ + P I +K ++ G+ + ++
Sbjct: 535 ASSDRGTYECIATSSTGS---ERRVVMLTMEERVTSPR-IEAASQKRTEVNFGDKLLLNC 590
Query: 2936 RTQGEPKPKAVPERIPGEPCVVD 2958
GEPKP+ + R+P + VVD
Sbjct: 591 SATGEPKPQ-IMWRLPSK-AVVD 611
Score = 61.7 bits (143), Expect = 5e-08
Identities = 60/239 (25%), Positives = 97/239 (40%), Gaps = 36/239 (15%)
Query: 3187 LTCQVIGSPPPKVSWYK--DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
L C+ +G+P P + W + G ++ K+ ++ Q TL I + D G Y +A N
Sbjct: 295 LPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASN 354
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
G H L V P +H G + + E PS VTW
Sbjct: 355 LFGTDHLHVTLSV-----VSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILA 409
Query: 3305 GVRL-----RPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ + SR+A++T+D L L ++ D G Y C ASN G+ S K++VI
Sbjct: 410 NQTVVSESSQGSRQAVVTVDGT----LVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVI 465
Query: 3360 GTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
PPV++ ++ + G+++ + C G P+P VYW+
Sbjct: 466 AA--------PPVILE------------QRRQVIVGTWGESLKLPCTAKGTPQPSVYWV 504
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 75.4 bits (177), Expect = 3e-12
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 11/185 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL-LDNKLKYRKKLVDGLITLE 2652
P F+ D T G+ +L C+ + P + W ++G + R ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+++ D YSCT +N G+IS +A L V + P+F R + D V
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLET-------PSFLRPLLDRTVTKGETAV 715
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C G P PK+ W KDD + R+ F+ A + +D+ D+G YTC+ N+
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERH--FFAAGNQLLIIVDSDV-SDAGKYTCEMSNT 772
Query: 2773 VWTDQ 2777
+ T++
Sbjct: 773 LGTER 777
Score = 73.3 bits (172), Expect = 1e-11
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 15/213 (7%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLE 3226
P FT D ++A RL C +G P P+++W KD G + + R + +
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY--KLHEGDE 3284
I ++D GVY TA+N++G++S + L V P F L PL + +G+
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTV------LETPSF---LRPLLDRTVTKGET 713
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + P + W +D L + R G L + DAG YTC S
Sbjct: 714 AVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA---GNQLLIIVDSDVSDAGKYTCEMS 770
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
N +G + ++ VI T P++ + D
Sbjct: 771 NTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDD 803
Score = 69.7 bits (163), Expect = 2e-10
Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L I AG A L C+ G P P + W K+G A D I D+ I
Sbjct: 609 PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI 668
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D G YSC A N+ G S A L V+ P F L D
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVLE-----------------------TPSFLRPLLD 705
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R V L C GSPPPK++W KD +V +R Q L I +++ D G
Sbjct: 706 RTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL--LIIVDSDVSDAG 763
Query: 3237 VYEVTARNNSG 3247
Y N G
Sbjct: 764 KYTCEMSNTLG 774
Score = 60.9 bits (141), Expect = 8e-08
Identities = 84/349 (24%), Positives = 136/349 (38%), Gaps = 50/349 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLL-----DNKLKYRK--- 2642
KP + ++A++GS + CS SSSD +T W ++ LL +N R
Sbjct: 498 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGG 557
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIR 2701
++++ L + + +Y C + N G + S A L V + P+FT++
Sbjct: 558 EVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-------NMLPSFTKTPM 610
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D A LEC G P P+I W KD P+ + + + +D E
Sbjct: 611 DLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI-E 669
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D G Y+C A+NS +S N LE+ P F L
Sbjct: 670 DIGVYSCTAQNSA---------------GSISANATLT--------VLET--PSFLRPLL 704
Query: 2821 DYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
D V +G T LQ G P ++ W ++ + R+ F G L + D ++
Sbjct: 705 DRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQLLIIVDSDVSD 761
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
+G YTC + G N ++V+ P+ P + + D +VG
Sbjct: 762 AGKYTCEMSNTLGTERGNVRLSVI-PTPTCDSPQMTAPSLDDDGWATVG 809
Score = 45.6 bits (103), Expect = 0.003
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GETA L C G P P + W K+ + + N L I D ++ D G+
Sbjct: 708 VTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL---LIIVDSDVSDAGK 764
Query: 3122 YSCEATNTHGKASTYARLAVVTDRT 3146
Y+CE +NT G RL+V+ T
Sbjct: 765 YTCEMSNTLGTERGNVRLSVIPTPT 789
Score = 43.2 bits (97), Expect = 0.017
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + G L+ G P ++ W ++G + R R+ V
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ-PSDLDGKPAVIVGRPEKDILISVGED 2930
+ DV + G+Y+C A ++ G++ NA +TV++ PS L RP D ++ GE
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFL---------RPLLDRTVTKGET 713
Query: 2931 INISFRTQGEPKPK 2944
+ G P PK
Sbjct: 714 AVLQCIAGGSPPPK 727
Score = 37.9 bits (84), Expect = 0.64
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK 2639
IS TL+ T P F L DRT +G L C S P + W ++ L +
Sbjct: 685 ISANATLTVLET--PSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--VVT 740
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
R G L ++++ SD+ +Y+C + N G + L V P+
Sbjct: 741 ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPT 787
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 75.4 bits (177), Expect = 3e-12
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 11/185 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL-LDNKLKYRKKLVDGLITLE 2652
P F+ D T G+ +L C+ + P + W ++G + R ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+++ D YSCT +N G+IS +A L V + P+F R + D V
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLET-------PSFLRPLLDRTVTKGETAV 715
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C G P PK+ W KDD + R+ F+ A + +D+ D+G YTC+ N+
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERH--FFAAGNQLLIIVDSDV-SDAGKYTCEMSNT 772
Query: 2773 VWTDQ 2777
+ T++
Sbjct: 773 LGTER 777
Score = 73.3 bits (172), Expect = 1e-11
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 15/213 (7%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLE 3226
P FT D ++A RL C +G P P+++W KD G + + R + +
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY--KLHEGDE 3284
I ++D GVY TA+N++G++S + L V P F L PL + +G+
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTV------LETPSF---LRPLLDRTVTKGET 713
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + P + W +D L + R G L + DAG YTC S
Sbjct: 714 AVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA---GNQLLIIVDSDVSDAGKYTCEMS 770
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
N +G + ++ VI T P++ + D
Sbjct: 771 NTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDD 803
Score = 69.7 bits (163), Expect = 2e-10
Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L I AG A L C+ G P P + W K+G A D I D+ I
Sbjct: 609 PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI 668
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D G YSC A N+ G S A L V+ P F L D
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVLE-----------------------TPSFLRPLLD 705
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R V L C GSPPPK++W KD +V +R Q L I +++ D G
Sbjct: 706 RTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL--LIIVDSDVSDAG 763
Query: 3237 VYEVTARNNSG 3247
Y N G
Sbjct: 764 KYTCEMSNTLG 774
Score = 60.9 bits (141), Expect = 8e-08
Identities = 84/349 (24%), Positives = 136/349 (38%), Gaps = 50/349 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLL-----DNKLKYRK--- 2642
KP + ++A++GS + CS SSSD +T W ++ LL +N R
Sbjct: 498 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGG 557
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIR 2701
++++ L + + +Y C + N G + S A L V + P+FT++
Sbjct: 558 EVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-------NMLPSFTKTPM 610
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D A LEC G P P+I W KD P+ + + + +D E
Sbjct: 611 DLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI-E 669
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D G Y+C A+NS +S N LE+ P F L
Sbjct: 670 DIGVYSCTAQNSA---------------GSISANATLT--------VLET--PSFLRPLL 704
Query: 2821 DYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
D V +G T LQ G P ++ W ++ + R+ F G L + D ++
Sbjct: 705 DRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQLLIIVDSDVSD 761
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
+G YTC + G N ++V+ P+ P + + D +VG
Sbjct: 762 AGKYTCEMSNTLGTERGNVRLSVI-PTPTCDSPQMTAPSLDDDGWATVG 809
Score = 45.6 bits (103), Expect = 0.003
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GETA L C G P P + W K+ + + N L I D ++ D G+
Sbjct: 708 VTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL---LIIVDSDVSDAGK 764
Query: 3122 YSCEATNTHGKASTYARLAVVTDRT 3146
Y+CE +NT G RL+V+ T
Sbjct: 765 YTCEMSNTLGTERGNVRLSVIPTPT 789
Score = 43.2 bits (97), Expect = 0.017
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + G L+ G P ++ W ++G + R R+ V
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ-PSDLDGKPAVIVGRPEKDILISVGED 2930
+ DV + G+Y+C A ++ G++ NA +TV++ PS L RP D ++ GE
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFL---------RPLLDRTVTKGET 713
Query: 2931 INISFRTQGEPKPK 2944
+ G P PK
Sbjct: 714 AVLQCIAGGSPPPK 727
Score = 37.9 bits (84), Expect = 0.64
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK 2639
IS TL+ T P F L DRT +G L C S P + W ++ L +
Sbjct: 685 ISANATLTVLET--PSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--VVT 740
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
R G L ++++ SD+ +Y+C + N G + L V P+
Sbjct: 741 ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPT 787
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 75.4 bits (177), Expect = 3e-12
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 11/185 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL-LDNKLKYRKKLVDGLITLE 2652
P F+ D T G+ +L C+ + P + W ++G + R ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+++ D YSCT +N G+IS +A L V + P+F R + D V
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLET-------PSFLRPLLDRTVTKGETAV 715
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C G P PK+ W KDD + R+ F+ A + +D+ D+G YTC+ N+
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERH--FFAAGNQLLIIVDSDV-SDAGKYTCEMSNT 772
Query: 2773 VWTDQ 2777
+ T++
Sbjct: 773 LGTER 777
Score = 73.3 bits (172), Expect = 1e-11
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 15/213 (7%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLE 3226
P FT D ++A RL C +G P P+++W KD G + + R + +
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY--KLHEGDE 3284
I ++D GVY TA+N++G++S + L V P F L PL + +G+
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTV------LETPSF---LRPLLDRTVTKGET 713
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + P + W +D L + R G L + DAG YTC S
Sbjct: 714 AVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA---GNQLLIIVDSDVSDAGKYTCEMS 770
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
N +G + ++ VI T P++ + D
Sbjct: 771 NTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDD 803
Score = 69.7 bits (163), Expect = 2e-10
Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L I AG A L C+ G P P + W K+G A D I D+ I
Sbjct: 609 PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI 668
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D G YSC A N+ G S A L V+ P F L D
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVLE-----------------------TPSFLRPLLD 705
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R V L C GSPPPK++W KD +V +R Q L I +++ D G
Sbjct: 706 RTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL--LIIVDSDVSDAG 763
Query: 3237 VYEVTARNNSG 3247
Y N G
Sbjct: 764 KYTCEMSNTLG 774
Score = 60.9 bits (141), Expect = 8e-08
Identities = 84/349 (24%), Positives = 136/349 (38%), Gaps = 50/349 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLL-----DNKLKYRK--- 2642
KP + ++A++GS + CS SSSD +T W ++ LL +N R
Sbjct: 498 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGG 557
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIR 2701
++++ L + + +Y C + N G + S A L V + P+FT++
Sbjct: 558 EVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-------NMLPSFTKTPM 610
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D A LEC G P P+I W KD P+ + + + +D E
Sbjct: 611 DLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI-E 669
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D G Y+C A+NS +S N LE+ P F L
Sbjct: 670 DIGVYSCTAQNSA---------------GSISANATLT--------VLET--PSFLRPLL 704
Query: 2821 DYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
D V +G T LQ G P ++ W ++ + R+ F G L + D ++
Sbjct: 705 DRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQLLIIVDSDVSD 761
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
+G YTC + G N ++V+ P+ P + + D +VG
Sbjct: 762 AGKYTCEMSNTLGTERGNVRLSVI-PTPTCDSPQMTAPSLDDDGWATVG 809
Score = 45.6 bits (103), Expect = 0.003
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GETA L C G P P + W K+ + + N L I D ++ D G+
Sbjct: 708 VTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL---LIIVDSDVSDAGK 764
Query: 3122 YSCEATNTHGKASTYARLAVVTDRT 3146
Y+CE +NT G RL+V+ T
Sbjct: 765 YTCEMSNTLGTERGNVRLSVIPTPT 789
Score = 43.2 bits (97), Expect = 0.017
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + G L+ G P ++ W ++G + R R+ V
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ-PSDLDGKPAVIVGRPEKDILISVGED 2930
+ DV + G+Y+C A ++ G++ NA +TV++ PS L RP D ++ GE
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFL---------RPLLDRTVTKGET 713
Query: 2931 INISFRTQGEPKPK 2944
+ G P PK
Sbjct: 714 AVLQCIAGGSPPPK 727
Score = 37.9 bits (84), Expect = 0.64
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK 2639
IS TL+ T P F L DRT +G L C S P + W ++ L +
Sbjct: 685 ISANATLTVLET--PSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--VVT 740
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
R G L ++++ SD+ +Y+C + N G + L V P+
Sbjct: 741 ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPT 787
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 75.4 bits (177), Expect = 3e-12
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 11/185 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL-LDNKLKYRKKLVDGLITLE 2652
P F+ D T G+ +L C+ + P + W ++G + R ++
Sbjct: 543 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 602
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+++ D YSCT +N G+IS +A L V + P+F R + D V
Sbjct: 603 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLET-------PSFLRPLLDRTVTKGETAV 655
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C G P PK+ W KDD + R+ F+ A + +D+ D+G YTC+ N+
Sbjct: 656 LQCIAGGSPPPKLNWTKDDSPLVVTERH--FFAAGNQLLIIVDSDV-SDAGKYTCEMSNT 712
Query: 2773 VWTDQ 2777
+ T++
Sbjct: 713 LGTER 717
Score = 73.3 bits (172), Expect = 1e-11
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 15/213 (7%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLE 3226
P FT D ++A RL C +G P P+++W KD G + + R + +
Sbjct: 543 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 602
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY--KLHEGDE 3284
I ++D GVY TA+N++G++S + L V P F L PL + +G+
Sbjct: 603 IVDVKIEDIGVYSCTAQNSAGSISANATLTV------LETPSF---LRPLLDRTVTKGET 653
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + P + W +D L + R G L + DAG YTC S
Sbjct: 654 AVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA---GNQLLIIVDSDVSDAGKYTCEMS 710
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
N +G + ++ VI T P++ + D
Sbjct: 711 NTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDD 743
Score = 69.7 bits (163), Expect = 2e-10
Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L I AG A L C+ G P P + W K+G A D I D+ I
Sbjct: 549 PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI 608
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D G YSC A N+ G S A L V+ P F L D
Sbjct: 609 EDIGVYSCTAQNSAGSISANATLTVLE-----------------------TPSFLRPLLD 645
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R V L C GSPPPK++W KD +V +R Q L I +++ D G
Sbjct: 646 RTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL--LIIVDSDVSDAG 703
Query: 3237 VYEVTARNNSG 3247
Y N G
Sbjct: 704 KYTCEMSNTLG 714
Score = 60.9 bits (141), Expect = 8e-08
Identities = 84/349 (24%), Positives = 136/349 (38%), Gaps = 50/349 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLL-----DNKLKYRK--- 2642
KP + ++A++GS + CS SSSD +T W ++ LL +N R
Sbjct: 438 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGG 497
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIR 2701
++++ L + + +Y C + N G + S A L V + P+FT++
Sbjct: 498 EVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-------NMLPSFTKTPM 550
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D A LEC G P P+I W KD P+ + + + +D E
Sbjct: 551 DLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI-E 609
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D G Y+C A+NS +S N LE+ P F L
Sbjct: 610 DIGVYSCTAQNSA---------------GSISANATLT--------VLET--PSFLRPLL 644
Query: 2821 DYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
D V +G T LQ G P ++ W ++ + R+ F G L + D ++
Sbjct: 645 DRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQLLIIVDSDVSD 701
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
+G YTC + G N ++V+ P+ P + + D +VG
Sbjct: 702 AGKYTCEMSNTLGTERGNVRLSVI-PTPTCDSPQMTAPSLDDDGWATVG 749
Score = 45.6 bits (103), Expect = 0.003
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GETA L C G P P + W K+ + + N L I D ++ D G+
Sbjct: 648 VTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL---LIIVDSDVSDAGK 704
Query: 3122 YSCEATNTHGKASTYARLAVVTDRT 3146
Y+CE +NT G RL+V+ T
Sbjct: 705 YTCEMSNTLGTERGNVRLSVIPTPT 729
Score = 43.2 bits (97), Expect = 0.017
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + G L+ G P ++ W ++G + R R+ V
Sbjct: 543 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 602
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ-PSDLDGKPAVIVGRPEKDILISVGED 2930
+ DV + G+Y+C A ++ G++ NA +TV++ PS L RP D ++ GE
Sbjct: 603 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFL---------RPLLDRTVTKGET 653
Query: 2931 INISFRTQGEPKPK 2944
+ G P PK
Sbjct: 654 AVLQCIAGGSPPPK 667
Score = 37.9 bits (84), Expect = 0.64
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK 2639
IS TL+ T P F L DRT +G L C S P + W ++ L +
Sbjct: 625 ISANATLTVLET--PSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--VVT 680
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
R G L ++++ SD+ +Y+C + N G + L V P+
Sbjct: 681 ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPT 727
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 75.4 bits (177), Expect = 3e-12
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 11/185 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL-LDNKLKYRKKLVDGLITLE 2652
P F+ D T G+ +L C+ + P + W ++G + R ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+++ D YSCT +N G+IS +A L V + P+F R + D V
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLET-------PSFLRPLLDRTVTKGETAV 715
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C G P PK+ W KDD + R+ F+ A + +D+ D+G YTC+ N+
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERH--FFAAGNQLLIIVDSDV-SDAGKYTCEMSNT 772
Query: 2773 VWTDQ 2777
+ T++
Sbjct: 773 LGTER 777
Score = 73.3 bits (172), Expect = 1e-11
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 15/213 (7%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLE 3226
P FT D ++A RL C +G P P+++W KD G + + R + +
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY--KLHEGDE 3284
I ++D GVY TA+N++G++S + L V P F L PL + +G+
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTV------LETPSF---LRPLLDRTVTKGET 713
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + P + W +D L + R G L + DAG YTC S
Sbjct: 714 AVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA---GNQLLIIVDSDVSDAGKYTCEMS 770
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
N +G + ++ VI T P++ + D
Sbjct: 771 NTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDD 803
Score = 69.7 bits (163), Expect = 2e-10
Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L I AG A L C+ G P P + W K+G A D I D+ I
Sbjct: 609 PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI 668
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D G YSC A N+ G S A L V+ P F L D
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVLE-----------------------TPSFLRPLLD 705
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R V L C GSPPPK++W KD +V +R Q L I +++ D G
Sbjct: 706 RTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL--LIIVDSDVSDAG 763
Query: 3237 VYEVTARNNSG 3247
Y N G
Sbjct: 764 KYTCEMSNTLG 774
Score = 60.9 bits (141), Expect = 8e-08
Identities = 84/349 (24%), Positives = 136/349 (38%), Gaps = 50/349 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLL-----DNKLKYRK--- 2642
KP + ++A++GS + CS SSSD +T W ++ LL +N R
Sbjct: 498 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGG 557
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIR 2701
++++ L + + +Y C + N G + S A L V + P+FT++
Sbjct: 558 EVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-------NMLPSFTKTPM 610
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D A LEC G P P+I W KD P+ + + + +D E
Sbjct: 611 DLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI-E 669
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D G Y+C A+NS +S N LE+ P F L
Sbjct: 670 DIGVYSCTAQNSA---------------GSISANATLT--------VLET--PSFLRPLL 704
Query: 2821 DYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
D V +G T LQ G P ++ W ++ + R+ F G L + D ++
Sbjct: 705 DRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQLLIIVDSDVSD 761
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
+G YTC + G N ++V+ P+ P + + D +VG
Sbjct: 762 AGKYTCEMSNTLGTERGNVRLSVI-PTPTCDSPQMTAPSLDDDGWATVG 809
Score = 45.6 bits (103), Expect = 0.003
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GETA L C G P P + W K+ + + N L I D ++ D G+
Sbjct: 708 VTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL---LIIVDSDVSDAGK 764
Query: 3122 YSCEATNTHGKASTYARLAVVTDRT 3146
Y+CE +NT G RL+V+ T
Sbjct: 765 YTCEMSNTLGTERGNVRLSVIPTPT 789
Score = 43.2 bits (97), Expect = 0.017
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + G L+ G P ++ W ++G + R R+ V
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ-PSDLDGKPAVIVGRPEKDILISVGED 2930
+ DV + G+Y+C A ++ G++ NA +TV++ PS L RP D ++ GE
Sbjct: 663 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFL---------RPLLDRTVTKGET 713
Query: 2931 INISFRTQGEPKPK 2944
+ G P PK
Sbjct: 714 AVLQCIAGGSPPPK 727
Score = 37.9 bits (84), Expect = 0.64
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK 2639
IS TL+ T P F L DRT +G L C S P + W ++ L +
Sbjct: 685 ISANATLTVLET--PSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--VVT 740
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
R G L ++++ SD+ +Y+C + N G + L V P+
Sbjct: 741 ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPT 787
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens cDNA
FLJ90440 fis, clone NT2RP3000921, weakly similar to TUMOR
SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 75.4 bits (177), Expect = 3e-12
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 11/185 (5%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVL-LDNKLKYRKKLVDGLITLE 2652
P F+ D T G+ +L C+ + P + W ++G + R ++
Sbjct: 181 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 240
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+++ D YSCT +N G+IS +A L V + P+F R + D V
Sbjct: 241 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLET-------PSFLRPLLDRTVTKGETAV 293
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C G P PK+ W KDD + R+ F+ A + +D+ D+G YTC+ N+
Sbjct: 294 LQCIAGGSPPPKLNWTKDDSPLVVTERH--FFAAGNQLLIIVDSDV-SDAGKYTCEMSNT 350
Query: 2773 VWTDQ 2777
+ T++
Sbjct: 351 LGTER 355
Score = 73.3 bits (172), Expect = 1e-11
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 15/213 (7%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKD-GEEVVYDKRRNKYQDEQFHTLE 3226
P FT D ++A RL C +G P P+++W KD G + + R + +
Sbjct: 181 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 240
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLY--KLHEGDE 3284
I ++D GVY TA+N++G++S + L V P F L PL + +G+
Sbjct: 241 IVDVKIEDIGVYSCTAQNSAGSISANATLTV------LETPSF---LRPLLDRTVTKGET 291
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + P + W +D L + R G L + DAG YTC S
Sbjct: 292 AVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA---GNQLLIIVDSDVSDAGKYTCEMS 348
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
N +G + ++ VI T P++ + D
Sbjct: 349 NTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDD 381
Score = 69.7 bits (163), Expect = 2e-10
Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L I AG A L C+ G P P + W K+G A D I D+ I
Sbjct: 187 PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI 246
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
+D G YSC A N+ G S A L V+ P F L D
Sbjct: 247 EDIGVYSCTAQNSAGSISANATLTVLE-----------------------TPSFLRPLLD 283
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
R V L C GSPPPK++W KD +V +R Q L I +++ D G
Sbjct: 284 RTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL--LIIVDSDVSDAG 341
Query: 3237 VYEVTARNNSG 3247
Y N G
Sbjct: 342 KYTCEMSNTLG 352
Score = 60.9 bits (141), Expect = 8e-08
Identities = 84/349 (24%), Positives = 136/349 (38%), Gaps = 50/349 (14%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVT--WYRNGVLL-----DNKLKYRK--- 2642
KP + ++A++GS + CS SSSD +T W ++ LL +N R
Sbjct: 76 KPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGG 135
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIR 2701
++++ L + + +Y C + N G + S A L V + P+FT++
Sbjct: 136 EVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-------NMLPSFTKTPM 188
Query: 2702 DTFHLAENELVLECRIRGQPLPKITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPE 2760
D A LEC G P P+I W KD P+ + + + +D E
Sbjct: 189 DLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKI-E 247
Query: 2761 DSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLT 2820
D G Y+C A+NS +S N LE+ P F L
Sbjct: 248 DIGVYSCTAQNSA---------------GSISANATLT--------VLET--PSFLRPLL 282
Query: 2821 DYQVARGGTIGLQVEIRGC-PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETE 2879
D V +G T LQ G P ++ W ++ + R+ F G L + D ++
Sbjct: 283 DRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERH---FFAAGNQLLIIVDSDVSD 339
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
+G YTC + G N ++V+ P+ P + + D +VG
Sbjct: 340 AGKYTCEMSNTLGTERGNVRLSVI-PTPTCDSPQMTAPSLDDDGWATVG 387
Score = 45.6 bits (103), Expect = 0.003
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GETA L C G P P + W K+ + + N L I D ++ D G+
Sbjct: 286 VTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQL---LIIVDSDVSDAGK 342
Query: 3122 YSCEATNTHGKASTYARLAVVTDRT 3146
Y+CE +NT G RL+V+ T
Sbjct: 343 YTCEMSNTLGTERGNVRLSVIPTPT 367
Score = 43.2 bits (97), Expect = 0.017
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 2813 PHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLA 2871
P F D + G L+ G P ++ W ++G + R R+ V
Sbjct: 181 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 240
Query: 2872 LSDVTETESGLYTCRAWSAHGNVDMNAAITVVQ-PSDLDGKPAVIVGRPEKDILISVGED 2930
+ DV + G+Y+C A ++ G++ NA +TV++ PS L RP D ++ GE
Sbjct: 241 IVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFL---------RPLLDRTVTKGET 291
Query: 2931 INISFRTQGEPKPK 2944
+ G P PK
Sbjct: 292 AVLQCIAGGSPPPK 305
Score = 37.9 bits (84), Expect = 0.64
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK 2639
IS TL+ T P F L DRT +G L C S P + W ++ L +
Sbjct: 263 ISANATLTVLET--PSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--VVT 318
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
R G L ++++ SD+ +Y+C + N G + L V P+
Sbjct: 319 ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPT 365
>X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein.
Length = 1138
Score = 73.7 bits (173), Expect = 1e-11
Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query: 2667 TVENENGAISTSANL---KVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
T+ E+ I+ + VY F+ S P FT+ + + + L C +RG P P
Sbjct: 1015 TMTKESAVIARDGKIYKNPVYEDFDFSEAP-MFTQPLVNRLCHSGYMATLNCSVRGNPKP 1073
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
KITW K+ I D RY+ F GVC L I P+P D GTY CKA N + T +I
Sbjct: 1074 KITWMKNKVAIVDDPRYRMFSNL-GVCTLEIGKPSPYDGGTYCCKAVNDLGTVEI 1127
Score = 60.9 bits (141), Expect = 8e-08
Identities = 33/90 (36%), Positives = 44/90 (48%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L +R + Y L C V G+P PK++W K+ +V D R + + TLEI
Sbjct: 1044 PMFTQPLVNRLCHSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNLGVCTLEI 1103
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ DGG Y A N+ G V C L V
Sbjct: 1104 GKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1133
Score = 56.4 bits (130), Expect = 2e-06
Identities = 60/210 (28%), Positives = 84/210 (40%), Gaps = 25/210 (11%)
Query: 2951 PGEPCVVDGGNNW---VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNS 3007
PG P +V + W V+L W A + Y ++ + R +E I P+
Sbjct: 930 PGPPQIVKIEDVWGRNVALTWTPPKDDGNAAITGYTIQKADKKSMEWLRVIEHIIEPVPH 989
Query: 3008 FDAFNLKQGEEYHFRVTPRNRYGWGE-SSQTSSSIGVGLAG--------------DRPEF 3052
+ L G EY+FRV N G E ++ T S + G + P F
Sbjct: 990 TE---LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1046
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCCLTI 3111
L +L +G A L CSV+G P P + WMKN V++ RM S C L I
Sbjct: 1047 TQPLVNRL-CHSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNLG--VCTLEI 1103
Query: 3112 KDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D G Y C+A N G +L V
Sbjct: 1104 GKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1133
Score = 54.4 bits (125), Expect = 7e-06
Identities = 28/90 (31%), Positives = 42/90 (46%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P+F+ L +R G L CSV + P +TW +N V + + +YR G+ TLE+
Sbjct: 1044 PMFTQPLVNRLCHSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNLGVCTLEI 1103
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
P D Y C N+ G + L+V
Sbjct: 1104 GKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1133
Score = 48.4 bits (110), Expect = 5e-04
Identities = 46/175 (26%), Positives = 73/175 (41%), Gaps = 9/175 (5%)
Query: 2598 TFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAV 2657
T LTD+T G + L C IS + P W +NG+ + + + + L + +A+
Sbjct: 435 TPLTDQTVNLGKEICLKCE-ISENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIDHAL 492
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
D +Y + N + ++ P + T ++ +A N+L LE I
Sbjct: 493 TEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTV-----IAGNKLRLEIPI 547
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
G+P PK W + DK I GR + D L ID +DSG Y +N
Sbjct: 548 SGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERDDSGVYHINLKN 601
Score = 47.2 bits (107), Expect = 0.001
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 15/167 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNG-VLLDNKLKYRKKLVDGLITLEVLNAVP 2658
L D T G RV+L C V S D V W++NG ++ + +YR ++ L + A
Sbjct: 347 LEDTTDYCGERVELECEV-SEDDAQVKWFKNGEEIILVQTRYRIRVEGKKHILIIEGATK 405
Query: 2659 SDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIR 2718
+D+A+YS + S +LK P +P+ T +L + E+ L+C I
Sbjct: 406 ADAADYSVMTTGGQSSAKLSVDLK--PLKILTPLTD-------QTVNLGK-EICLKCEI- 454
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
+ +P W K+ + R + + + +L ID+ ED G Y
Sbjct: 455 SENIPG-KWTKNGLPVQESDRLKVVH-KGRIHKLVIDHALTEDEGDY 499
Score = 44.4 bits (100), Expect = 0.007
Identities = 97/395 (24%), Positives = 154/395 (38%), Gaps = 62/395 (15%)
Query: 2583 KRTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPT--VTWYRNGVLLDNKLK 2639
KR++ R + F+ L V+ G RV+ V+ +DP V W +NG L K
Sbjct: 241 KRSI-REEKKSAAFAKILDPVYQVDKGGRVRF---VVELADPKLEVKWNKNGQELRPSTK 296
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS 2699
Y + L + N +D +EY T +E S L V P P T+
Sbjct: 297 YIFEDTRCQSILNIDNCQMTDDSEYYVTAGDEK----CSTELLV-----REP-PIMVTKQ 346
Query: 2700 IRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTP 2759
+ DT + LEC + + ++ WFK+ ++I + L I+ T
Sbjct: 347 LEDTTDYCGERVELECEV-SEDDAQVKWFKNGEEIILVQTRYRIRVEGKKHILIIEGATK 405
Query: 2760 EDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVL 2819
D+ Y SV T TG +S K + + L+ P L
Sbjct: 406 ADAADY------SVMT---------TGGQSSA--------KLSVDLKPLKILTP-----L 437
Query: 2820 TDYQVARGGTIGLQVEI-RGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTET 2878
TD V G I L+ EI P + W + G V E R +V + ++ L +
Sbjct: 438 TDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDR-LKVVHKGRIHKLVIDHALTE 494
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITVVQPSD--LDGKPAVIVGRPEKDILISVGEDINISFR 2936
+ G Y A A+ NV + A + V+ P LDG A + + + G + +
Sbjct: 495 DEGDYVF-APDAY-NVTLPAKVHVIDPPKIILDGLDA------DNTVTVIAGNKLRLEIP 546
Query: 2937 TQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKS 2971
GEP PKA+ R G+ +++G + ++P S
Sbjct: 547 ISGEPPPKAMWSR--GDKAIMEGSGRIRTESYPDS 579
Score = 40.3 bits (90), Expect = 0.12
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
++AG L + G+P P +W + + E +GR+ ++ L I DD G
Sbjct: 535 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 594
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y N G+A ++ VV
Sbjct: 595 YHINLKNEAGEAHASIKVKVV 615
Score = 39.9 bits (89), Expect = 0.16
Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 21/223 (9%)
Query: 3157 ERSAEVEGDYPP-QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN 3215
+ SA++ D P + L D+ V + L C++ + P K W K+G V R
Sbjct: 419 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLK 476
Query: 3216 KYQDEQFHTLEIAPTNLDDGG--VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCC-G 3272
+ H L I +D G V+ A N + H V+D P+ G
Sbjct: 477 VVHKGRIHKLVIDHALTEDEGDYVFAPDAYNVTLPAKVH---VIDP-------PKIILDG 526
Query: 3273 LEP--LYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAA 3330
L+ + G++LR+ + P W R + I T L +
Sbjct: 527 LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 586
Query: 3331 VTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVV 3373
D+GVY NE G A S KV+V+ +P + P V
Sbjct: 587 AERDDSGVYHINLKNEAGEAHASIKVKVV---DFPDPPVAPTV 626
Score = 35.1 bits (77), Expect = 4.5
Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 3273 LEPLYKLHEGDELRISAVVE-AYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAV 3331
L+P+Y++ +G +R VVE A P + V W ++G LRPS + I D Q L +
Sbjct: 257 LDPVYQVDKGGRVRF--VVELADPKLEVKWNKNGQELRPSTKYIFE-DTRCQSILNIDNC 313
Query: 3332 TTRDAGVYTCTASNE 3346
D Y TA +E
Sbjct: 314 QMTDDSEYYVTAGDE 328
Score = 35.1 bits (77), Expect = 4.5
Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + G L +RG P ++ W++ ++ + R R+F G+
Sbjct: 1041 SEAPMFTQPLVNRLCHSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRY-RMFSNLGVC 1099
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
TL + + + G Y C+A + G V++ + V
Sbjct: 1100 TLEIGKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1133
Score = 34.7 bits (76), Expect = 5.9
Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 1/79 (1%)
Query: 3280 HEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVY 3339
H G ++ V P +TW ++ V + R M G L + + D G Y
Sbjct: 1056 HSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNLGVCTLEIGKPSPYDGGTY 1114
Query: 3340 TCTASNEVGRASTSGKVEV 3358
C A N++G K+EV
Sbjct: 1115 CCKAVNDLGTVEIECKLEV 1133
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 73.3 bits (172), Expect = 1e-11
Identities = 74/293 (25%), Positives = 116/293 (39%), Gaps = 44/293 (15%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE +C G P P + W +NG +EE + G + LT+++I D G Y C
Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLIEENEKYI---LKGSNTELTVRNIINSDGGPYVC 281
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
ATN G+ A L V + +LK E + E G
Sbjct: 282 RATNKAGEDEKQAFLQVFVQPHI----IQLKNETTYE-NGQ------------------- 317
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVY-------DKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V L C G P P+++W + + + D R +L I L G
Sbjct: 318 VTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGR 377
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
Y+ A + G L ++ AP+F + +Y EG+ + IS V++ P
Sbjct: 378 YDCEAASRIGGHQKSMYLDIE------YAPKFISN-QTIYYSWEGNPINISCDVKSNPPA 430
Query: 3298 GVTWYRDGVRLRPSRRA--IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG 3348
+ W RD + L P++ + T ++ L +A + D G Y CTA+N +G
Sbjct: 431 SIHWRRDKLVL-PAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 70.9 bits (166), Expect = 7e-11
Identities = 73/307 (23%), Positives = 117/307 (38%), Gaps = 32/307 (10%)
Query: 3053 VDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIK 3112
V I ++++ GE+ TC+ G+P + W E R+ Q G LTI
Sbjct: 23 VTISLSKVELSVGESKFFTCTAIGEP-RSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIY 81
Query: 3113 DINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM 3172
+ NI+D G Y C+AT+ G+ EA L+ + PQ
Sbjct: 82 NANIEDAGIYRCQATDAKGQTQ--------------EATVVLEIYQKLTFREVVSPQEFK 127
Query: 3173 RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL 3232
+ D V C+V SP P VSW EEV N+ + L+I N
Sbjct: 128 QGEDAEV--------VCRVSSSPAPAVSWLYHNEEVT-TISDNRLAMLANNNLQILNINK 178
Query: 3233 DDGGVYEVTARNNS-GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVV 3291
D G+Y R + G + +V+ A P+ G+E+ S
Sbjct: 179 SDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNA----TAERGEEMTFSCRA 234
Query: 3292 EAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRAS 3351
P ++W+R+G + + + I+ + EL + + D G Y C A+N+ G
Sbjct: 235 SGSPEPAISWFRNGKLIEENEKYIL---KGSNTELTVRNIINSDGGPYVCRATNKAGEDE 291
Query: 3352 TSGKVEV 3358
++V
Sbjct: 292 KQAFLQV 298
Score = 65.3 bits (152), Expect = 4e-09
Identities = 51/189 (26%), Positives = 85/189 (44%), Gaps = 22/189 (11%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLIT-LEVLNAVPSDSA 2662
TA G + +C S +P ++W+RNG L++ KY ++ G T L V N + SD
Sbjct: 221 TAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKY---ILKGSNTELTVRNIINSDGG 277
Query: 2663 EYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C N+ G A L+V+ + P + +T + ++ L C G+P+
Sbjct: 278 PYVCRATNKAGEDEKQAFLQVF-------VQPHIIQLKNETTY-ENGQVTLVCDAEGEPI 329
Query: 2723 PKITW--------FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVW 2774
P+ITW F + + P DGR + G L I + SG Y C+A + +
Sbjct: 330 PEITWKRAVDGFTFTEGDKSP-DGRIEV-KGQHGSSSLHIKDVKLSGSGRYDCEAASRIG 387
Query: 2775 TDQITHFVN 2783
Q + +++
Sbjct: 388 GHQKSMYLD 396
Score = 63.3 bits (147), Expect = 1e-08
Identities = 52/208 (25%), Positives = 84/208 (40%), Gaps = 19/208 (9%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRN---GVLLDN 2636
+++ T+ +K F ++ + +G ++ C V SS P V+W Y N + DN
Sbjct: 102 TQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDN 161
Query: 2637 KLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTF 2696
+L L + L++LN SD Y C G + + +PP
Sbjct: 162 RL---AMLANN--NLQILNINKSDEGIYRC-----EGRVEARGEIDFRDIIVIVNVPPAI 211
Query: 2697 TRSIRDTFHLAE--NELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAI 2754
+ + AE E+ CR G P P I+WF++ K I + +Y L L +
Sbjct: 212 SMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKY---ILKGSNTELTV 268
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFV 2782
N D G Y C+A N D+ F+
Sbjct: 269 RNIINSDGGPYVCRATNKAGEDEKQAFL 296
Score = 59.7 bits (138), Expect = 2e-07
Identities = 88/369 (23%), Positives = 137/369 (37%), Gaps = 69/369 (18%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GE A + C V P P V W+ + EV + + + L I +IN DEG Y C
Sbjct: 129 GEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNN--LQILNINKSDEGIYRC 186
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
E G+ + R V + PP +M + A
Sbjct: 187 E-----GRVEARGEIDF----------------RDIIVIVNVPPAISMPQKSFNATAERG 225
Query: 3185 VRLT--CQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNL--DDGGVYEV 3240
+T C+ GSP P +SW+++G+ + + KY + +T E+ N+ DGG Y
Sbjct: 226 EEMTFSCRASGSPEPAISWFRNGKLI---EENEKYILKGSNT-ELTVRNIINSDGGPYVC 281
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFC-CGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
A N +G L V +V P E Y E ++ + E P +
Sbjct: 282 RATNKAGEDEKQAFLQV------FVQPHIIQLKNETTY---ENGQVTLVCDAEGEPIPEI 332
Query: 3300 TWYR--DGVRLRPSRRA----IMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS 3353
TW R DG ++ I + G L + V +G Y C A++ +G S
Sbjct: 333 TWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIGGHQKS 392
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
+ D+ Y+ P FI + EG+ + I C+V +P
Sbjct: 393 --------------------MYLDIEYA--PKFISNQTIYYSWEGNPINISCDVKSNPPA 430
Query: 3414 DVYWLRDFL 3422
++W RD L
Sbjct: 431 SIHWRRDKL 439
Score = 50.8 bits (116), Expect = 8e-05
Identities = 52/236 (22%), Positives = 93/236 (39%), Gaps = 32/236 (13%)
Query: 3188 TCQVIGSPPPKVSWYK-DGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
TC IG P + WY GE+++ +R + L I N++D G+Y A +
Sbjct: 41 TCTAIGEPR-SIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDAK 99
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW--YRD 3304
G +V++ Y F + P + +G++ + V + P+ V+W + +
Sbjct: 100 GQTQ-EATVVLE----IYQKLTFREVVSP-QEFKQGEDAEVVCRVSSSPAPAVSWLYHNE 153
Query: 3305 GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQT 3364
V R M + + QI + D G+Y C GR G+++ D
Sbjct: 154 EVTTISDNRLAMLANNNLQI----LNINKSDEGIYRCE-----GRVEARGEIDF--RDII 202
Query: 3365 SEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+PP + P +K ++ A G+ + C G P+P + W R+
Sbjct: 203 VIVNVPPAISMP-----------QKSFNATAERGEEMTFSCRASGSPEPAISWFRN 247
Score = 39.5 bits (88), Expect = 0.21
Identities = 40/184 (21%), Positives = 64/184 (34%), Gaps = 15/184 (8%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYR--NGVLLDNKLKYRKKLVD-----GLITLE 2652
L + T E +V L C P +TW R +G K ++ G +L
Sbjct: 307 LKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLH 366
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ + S S Y C + G S L + P F + + N +
Sbjct: 367 IKDVKLSGSGRYDCEAASRIGGHQKSMYLDI-------EYAPKFISNQTIYYSWEGNPIN 419
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPE-DSGTYTCKAEN 2771
+ C ++ P I W +D +P+ + G + PT + D G Y C A N
Sbjct: 420 ISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479
Query: 2772 SVWT 2775
+ T
Sbjct: 480 HIGT 483
Score = 39.1 bits (87), Expect = 0.28
Identities = 28/131 (21%), Positives = 52/131 (39%), Gaps = 9/131 (6%)
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F V++ + +G + + P V WL VT + N + L +
Sbjct: 117 FREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANN--NLQIL 174
Query: 2874 DVTETESGLYTCRAW-SAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDIN 2932
++ +++ G+Y C A G +D I +V PA+ + + + GE++
Sbjct: 175 NINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVP-----PAISMPQKSFNATAERGEEMT 229
Query: 2933 ISFRTQGEPKP 2943
S R G P+P
Sbjct: 230 FSCRASGSPEP 240
>BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein
protein.
Length = 143
Score = 73.3 bits (172), Expect = 1e-11
Identities = 51/151 (33%), Positives = 72/151 (47%), Gaps = 20/151 (13%)
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPP 3168
L I+ + D G Y+C ATN G+ S L V A E PP
Sbjct: 6 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV------------------AAKEAHKPP 47
Query: 3169 QFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ-FHTLE 3226
F +L++ V YPVRL C+V+G PPP++ W K+ E + + R + +QD + L
Sbjct: 48 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 107
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
I +D G Y V+A+N +G VSC L V
Sbjct: 108 IQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138
Score = 56.8 bits (131), Expect = 1e-06
Identities = 43/137 (31%), Positives = 61/137 (44%), Gaps = 3/137 (2%)
Query: 3223 HTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEG 3282
H+L I P D G+Y A N +G S LVV A+ P F L+ + +G
Sbjct: 4 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-AAKEAHKPPVFIEKLQNT-GVADG 61
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
+R+ V P + W ++ L S R M D G I L + T DAG YT
Sbjct: 62 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 121
Query: 3342 TASNEVGRASTSGKVEV 3358
+A NE G S + +++V
Sbjct: 122 SAKNEAGIVSCTARLDV 138
Score = 55.6 bits (128), Expect = 3e-06
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Query: 2646 DGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
+G+ +L + D+ Y+C N G S S L V + EA PP F +++T
Sbjct: 1 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK-PPVFIEKLQNTGV 58
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ LECR+ G P P+I W K+++ + S R G L I T ED+G
Sbjct: 59 ADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 118
Query: 2765 YTCKAEN 2771
YT A+N
Sbjct: 119 YTVSAKN 125
Score = 53.6 bits (123), Expect = 1e-05
Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 17/100 (17%)
Query: 3321 DGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPY 3380
+G L + VT+RDAG+YTC A+N G+ S S ++ V+ + +P
Sbjct: 1 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHKP------------- 46
Query: 3381 SKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P+FI K +++ +G V +EC V+G P P ++W ++
Sbjct: 47 ---PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKE 83
Score = 45.2 bits (102), Expect = 0.004
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
++ + + PVF L + +G V+L C V+ P + W + L + D
Sbjct: 40 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 99
Query: 2647 --GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
G I L + A D+ Y+ + +NE G +S +A L VY S
Sbjct: 100 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 141
Score = 44.0 bits (99), Expect = 0.010
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 2/97 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTS-QFNGFDCC 3108
P F++ L + G L C V G P P + W K + R++ Q N C
Sbjct: 47 PVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 105
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDR 3145
L I+ +D G Y+ A N G S ARL V R
Sbjct: 106 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISR 142
>BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein.
Length = 353
Score = 73.3 bits (172), Expect = 1e-11
Identities = 54/191 (28%), Positives = 78/191 (40%), Gaps = 9/191 (4%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFYLADGVCR--LAIDNPTPEDSGT 2764
+ C G P P+I+WFKD + S+GR + R L I++ D G
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGK 210
Query: 2765 YTCKAENSVWT 2775
Y C A NS T
Sbjct: 211 YECVATNSAGT 221
Score = 71.3 bits (167), Expect = 6e-11
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 33/241 (13%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V D + + +Q
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPV--DPATSNGRIKQ 186
Query: 3222 FHT--------LEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVV---DKGIRAYVAPEF 3269
+ L+I + D G YE A N++G S L V D G ++P+
Sbjct: 187 LRSGGSPIRGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQS 246
Query: 3270 C 3270
C
Sbjct: 247 C 247
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/242 (25%), Positives = 95/242 (39%), Gaps = 12/242 (4%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQ-IELALAAVT 3332
K+ E + P ++W++D + + P S I L G I AL +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIES 202
Query: 3333 TR--DAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
+ D G Y C A+N G R S + V G D S + P + S + + R
Sbjct: 203 SEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSPWCRH 262
Query: 3390 PR 3391
R
Sbjct: 263 AR 264
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 40.3 bits (90), Expect = 0.12
Identities = 59/206 (28%), Positives = 90/206 (43%), Gaps = 27/206 (13%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNG---F 3105
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPI 194
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHG 3131
L I+ D+G+Y C ATN+ G
Sbjct: 195 RGALQIESSEESDQGKYECVATNSAG 220
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
>AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 353
Score = 73.3 bits (172), Expect = 1e-11
Identities = 54/191 (28%), Positives = 78/191 (40%), Gaps = 9/191 (4%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LI 2649
KPVF D+T + G C P +TW + G + ++ + DG ++
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 2650 TLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAEN 2709
++ L V D A Y CT N G I+TSA L V + P P+ +
Sbjct: 92 RIQPLR-VQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKAR 150
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFYLADGVCR--LAIDNPTPEDSGT 2764
+ C G P P+I+WFKD + S+GR + R L I++ D G
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGK 210
Query: 2765 YTCKAENSVWT 2775
Y C A NS T
Sbjct: 211 YECVATNSAGT 221
Score = 71.3 bits (167), Expect = 6e-11
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 33/241 (13%)
Query: 3044 GLAGD-RPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQF 3102
G GD +P F+ + P L+G A+ C G+P P + WMK G +V + +
Sbjct: 26 GAHGDSKPVFIKV-PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3103 NGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAE 3161
+G L I+ + + DE Y C ATN+ G+ +T A+L+V+ + + +
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSI------- 137
Query: 3162 VEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQ 3221
D PQ + V+ + C G+P P++SW+KD V D + + +Q
Sbjct: 138 ---DMGPQLKV------VEKARTATMLCAAGGNPDPEISWFKDFLPV--DPATSNGRIKQ 186
Query: 3222 FHT--------LEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVV---DKGIRAYVAPEF 3269
+ L+I + D G YE A N++G S L V D G ++P+
Sbjct: 187 LRSGGSPIRGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQS 246
Query: 3270 C 3270
C
Sbjct: 247 C 247
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/242 (25%), Positives = 95/242 (39%), Gaps = 12/242 (4%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQ 3218
A GD P F D+ + CQ G P P+++W K G++V + ++
Sbjct: 25 AGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFD 84
Query: 3219 DEQFHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPL 3276
D L I P + D +YE TA N+ G ++ L V + + P F + P
Sbjct: 85 DGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE--EEQLPPGFPSIDMGPQ 142
Query: 3277 YKLHE-GDELRISAVVEAYPSVGVTWYRDGVRLRP--SRRAIMTLDRDGQ-IELALAAVT 3332
K+ E + P ++W++D + + P S I L G I AL +
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIES 202
Query: 3333 TR--DAGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
+ D G Y C A+N G R S + V G D S + P + S + + R
Sbjct: 203 SEESDQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSPWCRH 262
Query: 3390 PR 3391
R
Sbjct: 263 AR 264
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P +TW + G ++ R ++ D L + + RD +Y CTA+N +G +TS
Sbjct: 60 PKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTS 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ E ++PP P + + + K R T + C G+P P
Sbjct: 120 AKLSVL-----EEEQLPPGF--PSIDMGPQLKVVEKAR--------TATMLCAAGGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EISWFKDFLPV 175
Score = 40.3 bits (90), Expect = 0.12
Identities = 59/206 (28%), Positives = 90/206 (43%), Gaps = 27/206 (13%)
Query: 2939 GEPKPKAVPERIPGEPCVVDGG-NNWVSLAWPKSDPQTTAPVLAYKVESW---LIGAEGG 2994
G+ KP + ++P + + GG ++V A + P+ T KV S +I + G
Sbjct: 29 GDSKPVFI--KVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDG 86
Query: 2995 ARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDR--PEF 3052
A V L I PL Q +E + T N G TS+ + V L ++ P F
Sbjct: 87 AGSV-LRIQPLRV-------QRDEAIYECTATNSLG---EINTSAKLSV-LEEEQLPPGF 134
Query: 3053 VDILPG-QLKILA-GETANLTCSVKGKPVPGVVWMKNGHEVEEEA--GRMTSQFNG---F 3105
I G QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 135 PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPI 194
Query: 3106 DCCLTIKDINIDDEGRYSCEATNTHG 3131
L I+ D+G+Y C ATN+ G
Sbjct: 195 RGALQIESSEESDQGKYECVATNSAG 220
Score = 36.3 bits (80), Expect = 1.9
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 3363 QTSEPRIPPVVISPDVPYS---KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+T P +P +V+ V + +P+FI+ P G C+ G+PKP + W++
Sbjct: 9 RTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMK 68
Query: 3420 DFLKV 3424
KV
Sbjct: 69 KGKKV 73
>AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein.
Length = 163
Score = 73.3 bits (172), Expect = 1e-11
Identities = 50/143 (34%), Positives = 64/143 (44%), Gaps = 4/143 (2%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P+F R + V L+CQ++G+P P+VSW KD + V R QD + L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVD-KGIRAYVAPEFCCGLEPL-YKLHEGDEL 3285
L D G Y ARN G GL VD + A AP F L P ++ EG E
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFL--LRPTSIRVREGSEA 127
Query: 3286 RISAVVEAYPSVGVTWYRDGVRL 3308
V P V+W +DG RL
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRL 150
Score = 64.5 bits (150), Expect = 6e-09
Identities = 48/152 (31%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + G+ A L+C + G P P V W K+ V A +Q +G LTI D+ +
Sbjct: 16 PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ-DGDLYRLTILDLAL 74
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
D G+Y C A N G+A L V +A+A + P F +R
Sbjct: 75 GDSGQYVCRARNAIGEAFAAVGLQV-------DAEAAC---------AEQAPHFLLRPTS 118
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
RV+ C+V GSP P VSW KDG +
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRL 150
Score = 54.4 bits (125), Expect = 7e-06
Identities = 29/127 (22%), Positives = 52/127 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G L+C ++ + P V+W ++ + ++R L L +L+ DS +Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N G + L+V + P F +E CR+ G P P ++W
Sbjct: 84 ARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSW 143
Query: 2728 FKDDKQI 2734
KD +++
Sbjct: 144 SKDGRRL 150
Score = 50.4 bits (115), Expect = 1e-04
Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 18/140 (12%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVYT 3340
G + +S + P+ V+W +D + R L +DG + L + + D+G Y
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGAR--FRLAQDGDLYRLTILDLALGDSGQYV 81
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDT 3400
C A N +G A + ++V +E + P F+ +P S REG
Sbjct: 82 CRARNAIGEAFAAVGLQVDAEAACAE---------------QAPHFLLRPTSIRVREGSE 126
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
C V G P+P V W +D
Sbjct: 127 ATFRCRVGGSPRPAVSWSKD 146
Score = 49.2 bits (112), Expect = 3e-04
Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 21/157 (13%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+ L C+I G P P+++W KD + + + R++ D + RL I + DSG Y C+A
Sbjct: 26 DATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLTILDLALGDSGQYVCRA 84
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N++ F QV AE+ PHF T +V G
Sbjct: 85 RNAIGE-------AFAAVGLQVDAEAACAEQA-----------PHFLLRPTSIRVREGSE 126
Query: 2830 IGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQ 2865
+ + G P V W ++GR + E RV VE+
Sbjct: 127 ATFRCRVGGSPRPAVSWSKDGRRLGEP-DGPRVRVEE 162
Score = 39.5 bits (88), Expect = 0.21
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 3/135 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + V+ G L +I G PT +V W ++ + V R R+ + LY
Sbjct: 7 SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGAR-FRLAQDGDLY 65
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVG 2928
L + D+ +SG Y CRA +A G + V + + + RP I + G
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREG 124
Query: 2929 EDINISFRTQGEPKP 2943
+ R G P+P
Sbjct: 125 SEATFRCRVGGSPRP 139
Score = 37.5 bits (83), Expect = 0.84
Identities = 13/41 (31%), Positives = 23/41 (56%)
Query: 3380 YSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
+S P F+ +P++ G + C++VG+P P V W +D
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKD 46
Score = 35.9 bits (79), Expect = 2.6
Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG 3096
A P F+ + P +++ G A C V G P P V W K+G + E G
Sbjct: 106 AEQAPHFL-LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDG 155
>AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein
protein.
Length = 1235
Score = 73.3 bits (172), Expect = 1e-11
Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 17/187 (9%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
+R+TC+ G PPP + W +DG+ V R++ Q + +L I+ ++DGG Y A N
Sbjct: 1018 IRMTCRAEGFPPPAIEWQRDGQPV--SSPRHQLQPD--GSLVISRVAVEDGGFYTCVAFN 1073
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEF-CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
+ ++ V E GL P + EGD R+ VV A SV + W R
Sbjct: 1074 GQDR--------DQRWVQLRVLGELTISGLPPTVTVPEGDTARLLCVV-AGESVNIRWSR 1124
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+G+ ++ + DG L + + RD G YTC+A S S +V+V+
Sbjct: 1125 NGLPVQADGHRVHQ-SPDG--TLLIYNLRARDEGSYTCSAYQGSQAVSRSTEVKVVSPAP 1181
Query: 3364 TSEPRIP 3370
T++PR P
Sbjct: 1182 TAQPRDP 1188
Score = 51.6 bits (118), Expect = 5e-05
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 17/166 (10%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAE 2663
A G R+++TC P + W R+G + + R +L DG +L + D
Sbjct: 1012 ASPGQRIRMTCRAEGFPPPAIEWQRDGQPVSSP---RHQLQPDG--SLVISRVAVEDGGF 1066
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y+C N L+V S +PPT T DT L C + G+ +
Sbjct: 1067 YTCVAFNGQDRDQRWVQLRVLGELTISGLPPTVTVPEGDTARLL-------CVVAGESV- 1118
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
I W ++ + +DG ++ DG L I N D G+YTC A
Sbjct: 1119 NIRWSRNGLPVQADG-HRVHQSPDGT--LLIYNLRARDEGSYTCSA 1161
Score = 44.8 bits (101), Expect = 0.006
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 7/96 (7%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R++ E +P + W RDG + R L DG L ++ V D G YTC
Sbjct: 1015 GQRIRMTCRAEGFPPPAIEWQRDGQPVSSPRH---QLQPDG--SLVISRVAVEDGGFYTC 1069
Query: 3342 TASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPD 3377
A N R ++ V+G + + +PP V P+
Sbjct: 1070 VAFNGQDRDQRWVQLRVLG--ELTISGLPPTVTVPE 1103
Score = 44.4 bits (100), Expect = 0.007
Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 13/105 (12%)
Query: 3038 SSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGR 3097
SSS + LAG P V GQL L+CS P W K+G + + R
Sbjct: 842 SSSYRISLAGVEPSLVQAALGQL-------VRLSCSDDTAPESQAAWQKDGQPISSDRHR 894
Query: 3098 MTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
+ QF+G L I + +D G YSC +T G+ S +L ++
Sbjct: 895 L--QFDG---SLIIHPLQAEDAGTYSCGSTRP-GRDSQKIQLRII 933
Score = 44.4 bits (100), Expect = 0.007
Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
T EG +L C V++ + W RNG+ + + DG TL + N D
Sbjct: 1100 TVPEGDTARLLC-VVAGESVNIRWSRNGLPVQADGHRVHQSPDG--TLLIYNLRARDEGS 1156
Query: 2664 YSCTVENENGAISTSANLKVY-PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
Y+C+ + A+S S +KV P+ A P P R D LA +L+L+ ++ G
Sbjct: 1157 YTCSAYQGSQAVSRSTEVKVVSPAPTAQPRDP--GRDCVDQPELANCDLILQAQLCG 1211
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEE 3093
SS + + L ++P VD PGQ +TC +G P P + W ++G V
Sbjct: 991 SSHPQPANRLRLDQNQPRVVDASPGQ-------RIRMTCRAEGFPPPAIEWQRDGQPVSS 1043
Query: 3094 EAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTV 3147
++ D L I + ++D G Y+C A N + + +L V+ + T+
Sbjct: 1044 PRHQLQP-----DGSLVISRVAVEDGGFYTCVAFNGQDRDQRWVQLRVLGELTI 1092
Score = 42.7 bits (96), Expect = 0.022
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 3056 LPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDIN 3115
LP + + G+TA L C V G+ V + W +NG V+ + R+ +G L I ++
Sbjct: 1095 LPPTVTVPEGDTARLLCVVAGESV-NIRWSRNGLPVQADGHRVHQSPDG---TLLIYNLR 1150
Query: 3116 IDDEGRYSCEATNTHGKASTYARLAVVT 3143
DEG Y+C A S + VV+
Sbjct: 1151 ARDEGSYTCSAYQGSQAVSRSTEVKVVS 1178
Score = 36.7 bits (81), Expect = 1.5
Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
+ CR G P P I W +D + + S R+Q DG L I ED G YTC A N
Sbjct: 1020 MTCRAEGFPPPAIEWQRDGQPVSSP-RHQL--QPDG--SLVISRVAVEDGGFYTCVAFNG 1074
Query: 2773 VWTDQ 2777
DQ
Sbjct: 1075 QDRDQ 1079
Score = 35.9 bits (79), Expect = 2.6
Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 8/105 (7%)
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
P +EW R+G+ V+ + G +L +S V + G YTC A++
Sbjct: 1029 PPAIEWQRDGQPVSSPRHQLQ---PDG--SLVISRVAVEDGGFYTCVAFNGQDRDQRWVQ 1083
Query: 2900 ITVVQPSDLDGKPAVIV---GRPEKDILISVGEDINISFRTQGEP 2941
+ V+ + G P + G + + + GE +NI + G P
Sbjct: 1084 LRVLGELTISGLPPTVTVPEGDTARLLCVVAGESVNIRWSRNGLP 1128
Score = 34.7 bits (76), Expect = 5.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
VRL+C +P + +W KDG+ + D+ R ++ +L I P +D G Y
Sbjct: 865 VRLSCSDDTAPESQAAWQKDGQPISSDRHRLQFDG----SLIIHPLQAEDAGTY 914
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 72.9 bits (171), Expect = 2e-11
Identities = 67/272 (24%), Positives = 110/272 (40%), Gaps = 23/272 (8%)
Query: 3041 IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTS 3100
+G A + P F+ Q+ + +G A+ C G P P V W K G +V +
Sbjct: 24 VGGCAAEEPPRFIKEPKDQIGV-SGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIE 82
Query: 3101 QFNGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
L I+ + DE Y C A N+ G+ + +A+L V+ R
Sbjct: 83 FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL---------------RE 127
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
++ +P M + + V+ T + C G+P P+++W+KD V + +
Sbjct: 128 DQLPSGFP-NIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQ 186
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
+ L+I + D G YE A N++G S L V +R VAP F L ++
Sbjct: 187 LRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYV--RVRR-VAPRFSI-LPMSHE 242
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRP 3310
+ G + I+ V P V W + L P
Sbjct: 243 IMPGGNVNITCVAVGSPMPYVKWMQGAEDLTP 274
Score = 68.1 bits (159), Expect = 5e-10
Identities = 67/260 (25%), Positives = 107/260 (41%), Gaps = 31/260 (11%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTL 3225
PP+F +D+ + CQ G P P+V+W K G++V + ++ + L
Sbjct: 32 PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 91
Query: 3226 EIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
I P D VYE A+N+ G ++ H L V +R P ++ +L +
Sbjct: 92 RIQPLRTPRDENVYECVAQNSVGEITVHAKLTV---LREDQLPSGFPNIDMGPQLKVVER 148
Query: 3285 LRISAVV---EAYPSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
R + ++ P +TW++D + + PS + R G +++ + T D G Y
Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEET--DQGKYE 206
Query: 3341 CTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N G R S+ + V R+ V P F P S E G
Sbjct: 207 CVATNSAGVRYSSPANLYV---------RVRRVA----------PRFSILPMSHEIMPGG 247
Query: 3400 TVIIECEVVGDPKPDVYWLR 3419
V I C VG P P V W++
Sbjct: 248 NVNITCVAVGSPMPYVKWMQ 267
Score = 61.7 bits (143), Expect = 5e-08
Identities = 74/319 (23%), Positives = 121/319 (37%), Gaps = 37/319 (11%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK----LKYRKKLVDGLITLEVLNAV 2657
D+ V G C P VTW + G ++++ +++ + ++ ++ L
Sbjct: 41 DQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDES-AGAVLRIQPLRT- 98
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
P D Y C +N G I+ A L V + P + + C
Sbjct: 99 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 158
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G P P+ITWFKD + PS + L G L I++ D G Y C A NS
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA--LQIESSEETDQGKYECVATNSAG-- 214
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
V ++ SP + R+A P F + +++ GG + +
Sbjct: 215 -----VRYS------SPANLYVRVRRVA--------PRFSILPMSHEIMPGGNVNITCVA 255
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P V+W++ +T + G L L+DV ++ + + C A S+ G ++
Sbjct: 256 VGSPMPYVKWMQGAEDLT-----PEDDMPVGRNVLELTDVKDS-ANYHPCVAMSSLGVIE 309
Query: 2896 MNAAITVVQPSDLDGKPAV 2914
A ITV G P V
Sbjct: 310 AVAQITVKSLPKAPGTPMV 328
Score = 51.2 bits (117), Expect = 6e-05
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P VTW + G ++ R + D L + + T RD VY C A N VG +
Sbjct: 60 PKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ DQ +P P++ + + + R T + C G+P P
Sbjct: 120 AKLTVLREDQ-----LPSGF--PNIDMGPQLKVVERTR--------TATMLCAASGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EITWFKDFLPV 175
Score = 47.6 bits (108), Expect = 8e-04
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 9/125 (7%)
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ PP F + +D ++ C+ G P P++TW K K++ S R++ +
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQ-RFETIEFDES 86
Query: 2749 VCRLAIDNP--TPEDSGTYTCKAENSVWTDQITHFVNFTG-RESQVS---PNVVTAEKTR 2802
+ P TP D Y C A+NSV +IT T RE Q+ PN+ + +
Sbjct: 87 AGAVLRIQPLRTPRDENVYECVAQNSV--GEITVHAKLTVLREDQLPSGFPNIDMGPQLK 144
Query: 2803 IARQS 2807
+ ++
Sbjct: 145 VVERT 149
Score = 37.1 bits (82), Expect = 1.1
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
P F ILP +I+ G N+TC G P+P V WM+ ++ E
Sbjct: 232 PRF-SILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPE 275
Score = 35.1 bits (77), Expect = 4.5
Identities = 15/41 (36%), Positives = 20/41 (48%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
P FI++P+ G C+ GDPKP V W + KV
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKV 73
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 72.9 bits (171), Expect = 2e-11
Identities = 67/272 (24%), Positives = 110/272 (40%), Gaps = 23/272 (8%)
Query: 3041 IGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTS 3100
+G A + P F+ Q+ + +G A+ C G P P V W K G +V +
Sbjct: 24 VGGCAAEEPPRFIKEPKDQIGV-SGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIE 82
Query: 3101 QFNGFDCCLTIKDINID-DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS 3159
L I+ + DE Y C A N+ G+ + +A+L V+ R
Sbjct: 83 FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL---------------RE 127
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
++ +P M + + V+ T + C G+P P+++W+KD V + +
Sbjct: 128 DQLPSGFP-NIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQ 186
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEPLYK 3278
+ L+I + D G YE A N++G S L V +R VAP F L ++
Sbjct: 187 LRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYV--RVRR-VAPRFSI-LPMSHE 242
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRP 3310
+ G + I+ V P V W + L P
Sbjct: 243 IMPGGNVNITCVAVGSPMPYVKWMQGAEDLTP 274
Score = 68.1 bits (159), Expect = 5e-10
Identities = 67/260 (25%), Positives = 107/260 (41%), Gaps = 31/260 (11%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTL 3225
PP+F +D+ + CQ G P P+V+W K G++V + ++ + L
Sbjct: 32 PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 91
Query: 3226 EIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
I P D VYE A+N+ G ++ H L V +R P ++ +L +
Sbjct: 92 RIQPLRTPRDENVYECVAQNSVGEITVHAKLTV---LREDQLPSGFPNIDMGPQLKVVER 148
Query: 3285 LRISAVV---EAYPSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
R + ++ P +TW++D + + PS + R G +++ + T D G Y
Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEET--DQGKYE 206
Query: 3341 CTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
C A+N G R S+ + V R+ V P F P S E G
Sbjct: 207 CVATNSAGVRYSSPANLYV---------RVRRVA----------PRFSILPMSHEIMPGG 247
Query: 3400 TVIIECEVVGDPKPDVYWLR 3419
V I C VG P P V W++
Sbjct: 248 NVNITCVAVGSPMPYVKWMQ 267
Score = 61.7 bits (143), Expect = 5e-08
Identities = 74/319 (23%), Positives = 121/319 (37%), Gaps = 37/319 (11%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNK----LKYRKKLVDGLITLEVLNAV 2657
D+ V G C P VTW + G ++++ +++ + ++ ++ L
Sbjct: 41 DQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDES-AGAVLRIQPLRT- 98
Query: 2658 PSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRI 2717
P D Y C +N G I+ A L V + P + + C
Sbjct: 99 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 158
Query: 2718 RGQPLPKITWFKDDKQI-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTD 2776
G P P+ITWFKD + PS + L G L I++ D G Y C A NS
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA--LQIESSEETDQGKYECVATNSAG-- 214
Query: 2777 QITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEI 2836
V ++ SP + R+A P F + +++ GG + +
Sbjct: 215 -----VRYS------SPANLYVRVRRVA--------PRFSILPMSHEIMPGGNVNITCVA 255
Query: 2837 RGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVD 2895
G P V+W++ +T + G L L+DV ++ + + C A S+ G ++
Sbjct: 256 VGSPMPYVKWMQGAEDLT-----PEDDMPVGRNVLELTDVKDS-ANYHPCVAMSSLGVIE 309
Query: 2896 MNAAITVVQPSDLDGKPAV 2914
A ITV G P V
Sbjct: 310 AVAQITVKSLPKAPGTPMV 328
Score = 51.2 bits (117), Expect = 6e-05
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P VTW + G ++ R + D L + + T RD VY C A N VG +
Sbjct: 60 PKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVH 119
Query: 3354 GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKP 3413
K+ V+ DQ +P P++ + + + R T + C G+P P
Sbjct: 120 AKLTVLREDQ-----LPSGF--PNIDMGPQLKVVERTR--------TATMLCAASGNPDP 164
Query: 3414 DVYWLRDFLKV 3424
++ W +DFL V
Sbjct: 165 EITWFKDFLPV 175
Score = 47.6 bits (108), Expect = 8e-04
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 9/125 (7%)
Query: 2689 ASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADG 2748
A+ PP F + +D ++ C+ G P P++TW K K++ S R++ +
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQ-RFETIEFDES 86
Query: 2749 VCRLAIDNP--TPEDSGTYTCKAENSVWTDQITHFVNFTG-RESQVS---PNVVTAEKTR 2802
+ P TP D Y C A+NSV +IT T RE Q+ PN+ + +
Sbjct: 87 AGAVLRIQPLRTPRDENVYECVAQNSV--GEITVHAKLTVLREDQLPSGFPNIDMGPQLK 144
Query: 2803 IARQS 2807
+ ++
Sbjct: 145 VVERT 149
Score = 37.1 bits (82), Expect = 1.1
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
P F ILP +I+ G N+TC G P+P V WM+ ++ E
Sbjct: 232 PRF-SILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPE 275
Score = 35.1 bits (77), Expect = 4.5
Identities = 15/41 (36%), Positives = 20/41 (48%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
P FI++P+ G C+ GDPKP V W + KV
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKV 73
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 72.9 bits (171), Expect = 2e-11
Identities = 86/327 (26%), Positives = 128/327 (39%), Gaps = 44/327 (13%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAG--RMTSQFNGFDCCLTIKDINIDDEGRY 3122
G+T L C V G+P+P + W KN ++ G R+ +G L I + D G Y
Sbjct: 88 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSG---ALQISRLQPGDIGIY 144
Query: 3123 SCEATN-THGKASTYARLAVVTDRTVWEADAKLKRERSA-EVEGDYPPQFTMRLRDRRVQ 3180
C A N + A + +++D + L+R + +EG +D ++
Sbjct: 145 RCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEG----------KDAVLE 194
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
C V G PPP +W + GEEV+ R KY L I+ DD G+Y
Sbjct: 195 G-------C-VSGYPPPSFTWLR-GEEVI-QLRSKKYSLLGGSNLLISNVTDDDSGMYTC 244
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ +S L V V P F LY +E ++ V P V
Sbjct: 245 VVTYKNENISASAELTV------LVPPWFLNHPSNLYA-YESMDIEFECTVSGKPVPTVN 297
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
W ++G + PS + G L + V D G Y C A NE G A TS ++ V
Sbjct: 298 WMKNGDVVIPSDYFQIV----GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV-- 351
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFI 3387
+P IP + P P P+ +
Sbjct: 352 ----PKPAIPSSSVLPSAPRDVVPVLV 374
Score = 71.7 bits (168), Expect = 4e-11
Identities = 52/174 (29%), Positives = 75/174 (43%), Gaps = 15/174 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEY 2664
A+EG L V P+ TW R ++ +L+ +K + G L + N DS Y
Sbjct: 185 AIEGKDAVLEGCVSGYPPPSFTWLRGEEVI--QLRSKKYSLLGGSNLLISNVTDDDSGMY 242
Query: 2665 SCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPK 2724
+C V +N IS SA L V +PP F + + ++ EC + G+P+P
Sbjct: 243 TCVVTYKNENISASAELTVL-------VPPWFLNHPSNLYAYESMDIEFECTVSGKPVPT 295
Query: 2725 ITWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
+ W K+ D IPSD ++ G L I D G Y C AEN Q
Sbjct: 296 VNWMKNGDVVIPSD-----YFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQ 344
Score = 62.9 bits (146), Expect = 2e-08
Identities = 79/312 (25%), Positives = 134/312 (42%), Gaps = 38/312 (12%)
Query: 2620 SSDPTVTWYRNGVLLDNKLKYRKK-LVDGLITLE-VLNAV--PSDSAEYSCTVE-NENGA 2674
S P + W ++G+ L + RK+ L +G + ++ +L++ D Y C ++G+
Sbjct: 1 SGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGS 60
Query: 2675 I-STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQ 2733
I S +A + V A P+ F + ++L+C + G+P+P I W K+ +
Sbjct: 61 IISRTAKVAV-----AGPL--RFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQD 113
Query: 2734 I-PSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVS 2792
+ P G + L G L I P D G Y C A N + TG E++V
Sbjct: 114 LTPIPGDSRVVVLPSGA--LQISRLQPGDIGIYRCSARNPA--------SSRTGNEAEVR 163
Query: 2793 PNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC-PTRVEWLREGRS 2851
+ RQ +RP NV+ G L+ + G P WLR G
Sbjct: 164 ----ILSDPGLHRQLYFLQRP--SNVV----AIEGKDAVLEGCVSGYPPPSFTWLR-GEE 212
Query: 2852 VTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
V ++ ++ + G L +S+VT+ +SG+YTC + N+ +A +TV+ P
Sbjct: 213 VIQL--RSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNH 270
Query: 2912 PAVIVGRPEKDI 2923
P+ + DI
Sbjct: 271 PSNLYAYESMDI 282
Score = 60.9 bits (141), Expect = 8e-08
Identities = 63/268 (23%), Positives = 112/268 (41%), Gaps = 35/268 (13%)
Query: 3158 RSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKY 3217
R+A+V P +F + V L C+VIG P P + W K+ +++ ++
Sbjct: 64 RTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRV 123
Query: 3218 QDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVS---CHCGLVVDKGIRAYVAPEFCCGLE 3274
L+I+ D G+Y +ARN + + + ++ D G+ + F
Sbjct: 124 VVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQL--YFLQRPS 181
Query: 3275 PLYKLHEGDELRISAVVEAYPSVGVTWYR--DGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
+ + EG + + V YP TW R + ++LR + +++ G L ++ VT
Sbjct: 182 NVVAI-EGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLL-----GGSNLLISNVT 235
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRS 3392
D+G+YTC + + S S ++ V+ VP P F+ P +
Sbjct: 236 DDDSGMYTCVVTYKNENISASAELTVL------------------VP----PWFLNHPSN 273
Query: 3393 SEAREGDTVIIECEVVGDPKPDVYWLRD 3420
A E + EC V G P P V W+++
Sbjct: 274 LYAYESMDIEFECTVSGKPVPTVNWMKN 301
Score = 57.6 bits (133), Expect = 7e-07
Identities = 80/341 (23%), Positives = 128/341 (37%), Gaps = 36/341 (10%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
TA G V L C VI PT+ W +N L + +V L++ P D
Sbjct: 84 TAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGI 143
Query: 2664 YSCTVEN-ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPL 2722
Y C+ N + A +++ S F + + + + VLE + G P
Sbjct: 144 YRCSARNPASSRTGNEAEVRIL-SDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPP 202
Query: 2723 PKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFV 2782
P TW + ++ I R + + L G L I N T +DSG YTC
Sbjct: 203 PSFTWLRGEEVIQL--RSKKYSLLGG-SNLLISNVTDDDSGMYTCVV------------- 246
Query: 2783 NFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT- 2841
T + +S +AE T + P F N ++ I + + G P
Sbjct: 247 --TYKNENIS---ASAELTVLV-------PPWFLNHPSNLYAYESMDIEFECTVSGKPVP 294
Query: 2842 RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
V W++ G +V + F G L + V +++ G Y C A + GN +A +
Sbjct: 295 TVNWMKNG----DVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLI 350
Query: 2902 VVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
V +P+ R +L+S + +S+R E K
Sbjct: 351 VPKPAIPSSSVLPSAPRDVVPVLVS-SRFVRLSWRPPAEAK 390
Score = 56.8 bits (131), Expect = 1e-06
Identities = 63/262 (24%), Positives = 98/262 (37%), Gaps = 37/262 (14%)
Query: 3002 ITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGD----RPEFVDILP 3057
+ P + L+ G+ +R + RN SS+T + V + D R + P
Sbjct: 125 VLPSGALQISRLQPGDIGIYRCSARNP----ASSRTGNEAEVRILSDPGLHRQLYFLQRP 180
Query: 3058 GQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID 3117
+ + G+ A L V G P P W++ G EV + + S G + L I ++ D
Sbjct: 181 SNVVAIEGKDAVLEGCVSGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSN--LLISNVTDD 237
Query: 3118 DEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
D G Y+C T + S A L V+ PP F +
Sbjct: 238 DSGMYTCVVTYKNENISASAELTVLV-----------------------PPWFLNHPSNL 274
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
+ + C V G P P V+W K+G+ V+ + +Q L I D G
Sbjct: 275 YAYESMDIEFECTVSGKPVPTVNWMKNGDVVI---PSDYFQIVGGSNLRILGVVKSDEGF 331
Query: 3238 YEVTARNNSGAVSCHCGLVVDK 3259
Y+ A N +G L+V K
Sbjct: 332 YQCVAENEAGNAQTSAQLIVPK 353
Score = 53.2 bits (122), Expect = 2e-05
Identities = 48/180 (26%), Positives = 73/180 (40%), Gaps = 6/180 (3%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F ++ A E ++ C+V PTV W +NG ++ ++ + G L +
Sbjct: 265 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQ---IVGGSNLRI 321
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV-YPSFEASPIPPTFTRSIRDTFHLAENELV 2712
L V SD Y C ENE G TSA L V P+ +S + P+ R + ++ +
Sbjct: 322 LGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVL-VSSRFVR 380
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD-GVCRLAIDNPTPEDSGTYTCKAEN 2771
L R + I F D R +A G +L + N PE T+ A N
Sbjct: 381 LSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYN 440
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 72.9 bits (171), Expect = 2e-11
Identities = 71/296 (23%), Positives = 119/296 (40%), Gaps = 34/296 (11%)
Query: 3066 ETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
ET ++ C G P+P + W K+ + + R +G L I+ + +D G + C
Sbjct: 402 ETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG---LRIQKLRPEDSGIFQC 458
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
A+N G+ T+ L V + P FT R D V
Sbjct: 459 FASNEGGEIQTHTYLDVT----------------------NIAPVFTQRPVDTTVTDGMT 496
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+V G+P P ++W ++ + R ++ + L+IAP + D G Y A
Sbjct: 497 AILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAA 556
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N G+++ L V PE + + L A + S+ W +
Sbjct: 557 NTEGSLNASATLTVWNRTSIVHPPE-----DHVVIKGTTATLHCGATHDPRVSLRYVWKK 611
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
D V L PS + + +++DG L ++ + D G Y+C +E G S ++EVI
Sbjct: 612 DNVALTPSSTSRIVVEKDG--SLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVI 665
Score = 72.5 bits (170), Expect = 2e-11
Identities = 93/327 (28%), Positives = 129/327 (39%), Gaps = 48/327 (14%)
Query: 3057 PGQLKILAGET-ANLTCSVKGKPVP--GVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKD 3113
PG ++AG + L C +PV V W +NG R+TS + F LTI +
Sbjct: 299 PGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGV-------RITSGLHSFGRHLTISN 351
Query: 3114 INIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMR 3173
D G Y CEA G A AR A A L +E PP FT
Sbjct: 352 PTSADTGPYVCEAA-LPGSAFEPAR-----------ATAFL-----FIIE---PPYFTAE 391
Query: 3174 LRDR-RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTLEIAPTN 3231
R + V + CQ +G P P + WYKD + + +N +Y+ L I
Sbjct: 392 PESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISI--SRLQNPRYKVLASGGLRIQKLR 449
Query: 3232 LDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAV 3290
+D G+++ A N G + H L V +AP F P+ + +G +
Sbjct: 450 PEDSGIFQCFASNEGGEIQTHTYLDVTN-----IAPVFT--QRPVDTTVTDGMTAILRCE 502
Query: 3291 VEAYPSVGVTWYRDGVRLRPSRRAI---MTLDRDGQIELALAAVTTRDAGVYTCTASNEV 3347
V P +TW R+ L I M L+ G L +A V +DAG YTC A+N
Sbjct: 503 VSGAPKPAITWKRENHILASGSVRIPRFMLLESGG---LQIAPVFIQDAGNYTCYAANTE 559
Query: 3348 GRASTSGKVEVIGTDQTSEPRIPPVVI 3374
G + S + V P VVI
Sbjct: 560 GSLNASATLTVWNRTSIVHPPEDHVVI 586
Score = 68.5 bits (160), Expect = 4e-10
Identities = 57/203 (28%), Positives = 85/203 (41%), Gaps = 12/203 (5%)
Query: 2594 PVFSTFLTDRTAVEGSR-VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKK-LVDGLITL 2651
P F+ R + E V + C + PT+ WY++ + + R K L G + +
Sbjct: 386 PYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRI 445
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENEL 2711
+ L P DS + C NE G I T L V + I P FT+ DT
Sbjct: 446 QKLR--PEDSGIFQCFASNEGGEIQTHTYLDV------TNIAPVFTQRPVDTTVTDGMTA 497
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+L C + G P P ITW +++ + S R F L + L I +D+G YTC A
Sbjct: 498 ILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLES-GGLQIAPVFIQDAGNYTCYAA 556
Query: 2771 NSVWTDQITHFVNFTGRESQVSP 2793
N+ + + + R S V P
Sbjct: 557 NTEGSLNASATLTVWNRTSIVHP 579
Score = 58.0 bits (134), Expect = 6e-07
Identities = 55/194 (28%), Positives = 81/194 (41%), Gaps = 22/194 (11%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
LTC GS P + W +D E+ KY L D G Y RN
Sbjct: 124 LTCLAEGSWPLEFKWMRDDSELTTYSSEYKYIIPSLQKL--------DAGFYRCVVRNRM 175
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAV-VEAYPSVGVTWYRDG 3305
GA+ L ++ F + + +G ++ + + +YP VTW+R+G
Sbjct: 176 GAL-----LQRKSEVQVAYMGSFM-DTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREG 229
Query: 3306 VRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEV-GRASTSGKVEV-IGTD- 3362
++ PS R +TL+ +L + A TT DAG Y A NE G TS + + I D
Sbjct: 230 HKIIPSNRIAITLEN----QLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDV 285
Query: 3363 QTSEPRIPPVVISP 3376
T E P +V+ P
Sbjct: 286 GTPETMAPTIVVPP 299
Score = 52.8 bits (121), Expect = 2e-05
Identities = 68/277 (24%), Positives = 106/277 (38%), Gaps = 38/277 (13%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGS-PPPKVSWYKDGEEVVYDKRRN 3215
+R +EV+ Y F + + V L I S P P+V+W+++G +++ R
Sbjct: 180 QRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIA 239
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARN-----NSGAVSCHCGLVVDKGIRAYVAPEFC 3270
+ Q L I T D G Y V A N N + H + D G +AP
Sbjct: 240 ITLENQ---LVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIV 296
Query: 3271 CGLEPLYKLHEGDELRISAVVEAYP--SVGVTWYRDGVRLRPSRRAIMTLDRDGQIELAL 3328
+ E + + A P + VTW R+GVR+ L G+ L +
Sbjct: 297 VPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSG------LHSFGR-HLTI 349
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
+ T+ D G Y C A+ G A + +I P P F
Sbjct: 350 SNPTSADTGPYVCEAALP-GSAFEPARATAF-----------LFIIEP-------PYFTA 390
Query: 3389 KPRSS-EAREGDTVIIECEVVGDPKPDVYWLRDFLKV 3424
+P S A +TV I C+ +G P P + W +D + +
Sbjct: 391 EPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISI 427
Score = 46.4 bits (105), Expect = 0.002
Identities = 44/165 (26%), Positives = 67/165 (40%), Gaps = 34/165 (20%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVG----------VTWYRDGVRLRPSRRAI 3315
A F +EP Y E E RISA VE +G + WY+D + + +
Sbjct: 376 ATAFLFIIEPPYFTAE-PESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPR 434
Query: 3316 MTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVIS 3375
+ G L + + D+G++ C ASNE G T ++V
Sbjct: 435 YKVLASGG--LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNI-------------- 478
Query: 3376 PDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P+F ++P + +G T I+ CEV G PKP + W R+
Sbjct: 479 -------APVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRE 516
Score = 38.3 bits (85), Expect = 0.48
Identities = 46/176 (26%), Positives = 71/176 (40%), Gaps = 20/176 (11%)
Query: 2603 RTAVEGSRVKLTCSVISSSD-PTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
+T +G L I+S P VTW+R G + + L + L+ +L SD+
Sbjct: 200 KTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLV---ILATTTSDA 256
Query: 2662 AEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSI-----RDTFHLAENELVLEC 2715
Y NE NG TS + + + + P T +I + +E LEC
Sbjct: 257 GAYYVQAVNEKNGENKTSPFIHLSIARDVGT-PETMAPTIVVPPGNRSVVAGSSETTLEC 315
Query: 2716 RIRGQPLP--KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+P+ +TW ++ +I S L L I NPT D+G Y C+A
Sbjct: 316 IASARPVEDLSVTWKRNGVRITSG-------LHSFGRHLTISNPTSADTGPYVCEA 364
Score = 35.9 bits (79), Expect = 2.6
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 17/166 (10%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
+EG+R+ LTC S W R+ L K ++ L L D+ Y
Sbjct: 117 LEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYIIPSLQKL--------DAGFYR 168
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C V N GA+ L+ + + + R T ++ I P P++
Sbjct: 169 CVVRNRMGAL-----LQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQV 223
Query: 2726 TWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
TWF++ +I R A L + +L I T D+G Y +A N
Sbjct: 224 TWFREGHKIIPSNRI-AITLEN---QLVILATTTSDAGAYYVQAVN 265
>AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein.
Length = 504
Score = 72.9 bits (171), Expect = 2e-11
Identities = 93/391 (23%), Positives = 148/391 (37%), Gaps = 43/391 (10%)
Query: 3050 PEFVD-ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
P+ D ++P Q+ L G T L C V+G P P +W K+G + R G
Sbjct: 29 PKMADKVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---- 83
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD----RTVWEADAKLKRERSAEVEG 3164
L +K + +D G Y C+ATN G S L V+ D + D+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQ 143
Query: 3165 DYPPQFTMRLRDRRVQATYP----VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
P+FT + RR P VRL C G P P ++W KD + + + + +
Sbjct: 144 WARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKK 203
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH 3280
TL + +D G Y N +GA++ + V + R + G P+
Sbjct: 204 --WTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTR---SKPVLTGTHPVNTTV 258
Query: 3281 E-GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQ--IELALAAVTTR--- 3334
+ G V + + W + V R T+D GQ + L V +R
Sbjct: 259 DFGGTTSFQCKVRSDVKPVIQWLK-RVEYGAEGRHNSTIDVGGQKFVVLPTGDVWSRPDG 317
Query: 3335 --------------DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPY 3380
DAG+Y C +N +G + S + V+ +P+ PPV S
Sbjct: 318 SYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVL---PDPKPQGPPVASSSSATS 374
Query: 3381 SKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
P+ I P + G ++ C+ P
Sbjct: 375 LPWPVVIGIPAGAVFILGTLLLWLCQAQKKP 405
Score = 64.9 bits (151), Expect = 5e-09
Identities = 72/278 (25%), Positives = 110/278 (39%), Gaps = 48/278 (17%)
Query: 3167 PPQFTMRLRDRRV-QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP+ ++ R+V + VRL C V G PPP W KDG + R + + L
Sbjct: 28 PPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQ---GL 84
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI---RAYVAPEFCCG---------- 3272
++ +D GVY A N G++S + LVV I + + P+ G
Sbjct: 85 KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQW 144
Query: 3273 LEPLY----KLHE-------GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
P + K+ G +R+ V +P +TW +D L R R
Sbjct: 145 ARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRK 201
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ L+L + D+G YTC SN G + + KV+VI R PV+
Sbjct: 202 KKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI-----QRTRSKPVLTG------ 250
Query: 3382 KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
P ++ G T +C+V D KP + WL+
Sbjct: 251 ------THPVNTTVDFGGTTSFQCKVRSDVKPVIQWLK 282
Score = 57.2 bits (132), Expect = 1e-06
Identities = 64/273 (23%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 2681 LKVYPSFEASPIPPTFTRSI--RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG 2738
L +P A+ PP + R L + L+C + G P P W KD + I S G
Sbjct: 16 LGAFPPAAAARGPPKMADKVVPRQVARLGRT-VRLQCPVEGDPPPLTMWTKDGRTIHS-G 73
Query: 2739 RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT-----GRESQVSP 2793
+ L G L + ED+G Y CKA N + + + + G+ES + P
Sbjct: 74 WSRFRVLPQG---LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKES-LGP 129
Query: 2794 NVVTAEKTRIARQSLESRRPHFGNVLTDYQVAR--GGTIGLQVEIRGCPTR-VEWLREGR 2850
+ + + A Q R + + +AR G ++ L+ G P + W+++ +
Sbjct: 130 DSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQ 189
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
++T R + +TL+L ++ +SG YTCR + G ++ + V+Q +
Sbjct: 190 ALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--RS 244
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP V+ G + + G + + + + KP
Sbjct: 245 KP-VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Score = 52.8 bits (121), Expect = 2e-05
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNK--LKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V+L C P +TW ++ L + RKK TL + N P DS +Y+
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKW----TLSLKNLRPEDSGKYT 220
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C V N GAI+ + + V + P+ T T + T +C++R P I
Sbjct: 221 CRVSNRAGAINATYKVDVIQRTRSKPV-LTGTHPVNTTVDFG-GTTSFQCKVRSDVKPVI 278
Query: 2726 TWFKDDKQIPSDGRYQA 2742
W K + ++GR+ +
Sbjct: 279 QWLK-RVEYGAEGRHNS 294
Score = 48.4 bits (110), Expect = 5e-04
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R+ VE P W +DG + L + L + V DAGVY C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG----LKVKQVEREDAGVYVC 99
Query: 3342 TASNEVGRASTS-----------GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
A+N G S + GK E +G D +S + P P +P +R+
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGK-ESLGPDSSSGGQEDPASQQWARPRFTQPSKMRR- 157
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R G +V ++C G P+PD+ W++D
Sbjct: 158 RVIARPVGSSVRLKCVASGHPRPDITWMKD 187
Score = 41.1 bits (92), Expect = 0.068
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 3049 RPEFVDILPGQLKILA---GETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNG 3104
RP F + +++A G + L C G P P + WMK+ + EA +
Sbjct: 146 RPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKK--- 202
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L++K++ +D G+Y+C +N G + ++ V+
Sbjct: 203 -KWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239
>AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth factor
receptor 5 protein.
Length = 504
Score = 72.9 bits (171), Expect = 2e-11
Identities = 93/391 (23%), Positives = 148/391 (37%), Gaps = 43/391 (10%)
Query: 3050 PEFVD-ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
P+ D ++P Q+ L G T L C V+G P P +W K+G + R G
Sbjct: 29 PKMADKVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---- 83
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD----RTVWEADAKLKRERSAEVEG 3164
L +K + +D G Y C+ATN G S L V+ D + D+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQ 143
Query: 3165 DYPPQFTMRLRDRRVQATYP----VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
P+FT + RR P VRL C G P P ++W KD + + + + +
Sbjct: 144 WARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKK 203
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLH 3280
TL + +D G Y N +GA++ + V + R + G P+
Sbjct: 204 --WTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTR---SKPVLTGTHPVNTTV 258
Query: 3281 E-GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQ--IELALAAVTTR--- 3334
+ G V + + W + V R T+D GQ + L V +R
Sbjct: 259 DFGGTTSFQCKVRSDVKPVIQWLK-RVEYGAEGRHNSTIDVGGQKFVVLPTGDVWSRPDG 317
Query: 3335 --------------DAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPY 3380
DAG+Y C +N +G + S + V+ +P+ PPV S
Sbjct: 318 SYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVL---PDPKPQGPPVASSSSATS 374
Query: 3381 SKEPMFIRKPRSSEAREGDTVIIECEVVGDP 3411
P+ I P + G ++ C+ P
Sbjct: 375 LPWPVVIGIPAGAVFILGTLLLWLCQAQKKP 405
Score = 64.9 bits (151), Expect = 5e-09
Identities = 72/278 (25%), Positives = 110/278 (39%), Gaps = 48/278 (17%)
Query: 3167 PPQFTMRLRDRRV-QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP+ ++ R+V + VRL C V G PPP W KDG + R + + L
Sbjct: 28 PPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQ---GL 84
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI---RAYVAPEFCCG---------- 3272
++ +D GVY A N G++S + LVV I + + P+ G
Sbjct: 85 KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQW 144
Query: 3273 LEPLY----KLHE-------GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
P + K+ G +R+ V +P +TW +D L R R
Sbjct: 145 ARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRK 201
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ L+L + D+G YTC SN G + + KV+VI R PV+
Sbjct: 202 KKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI-----QRTRSKPVLTG------ 250
Query: 3382 KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
P ++ G T +C+V D KP + WL+
Sbjct: 251 ------THPVNTTVDFGGTTSFQCKVRSDVKPVIQWLK 282
Score = 57.2 bits (132), Expect = 1e-06
Identities = 64/273 (23%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 2681 LKVYPSFEASPIPPTFTRSI--RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG 2738
L +P A+ PP + R L + L+C + G P P W KD + I S G
Sbjct: 16 LGAFPPAAAARGPPKMADKVVPRQVARLGRT-VRLQCPVEGDPPPLTMWTKDGRTIHS-G 73
Query: 2739 RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT-----GRESQVSP 2793
+ L G L + ED+G Y CKA N + + + + G+ES + P
Sbjct: 74 WSRFRVLPQG---LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKES-LGP 129
Query: 2794 NVVTAEKTRIARQSLESRRPHFGNVLTDYQVAR--GGTIGLQVEIRGCPTR-VEWLREGR 2850
+ + + A Q R + + +AR G ++ L+ G P + W+++ +
Sbjct: 130 DSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQ 189
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
++T R + +TL+L ++ +SG YTCR + G ++ + V+Q +
Sbjct: 190 ALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--RS 244
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP V+ G + + G + + + + KP
Sbjct: 245 KP-VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Score = 52.8 bits (121), Expect = 2e-05
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNK--LKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V+L C P +TW ++ L + RKK TL + N P DS +Y+
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKW----TLSLKNLRPEDSGKYT 220
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C V N GAI+ + + V + P+ T T + T +C++R P I
Sbjct: 221 CRVSNRAGAINATYKVDVIQRTRSKPV-LTGTHPVNTTVDFG-GTTSFQCKVRSDVKPVI 278
Query: 2726 TWFKDDKQIPSDGRYQA 2742
W K + ++GR+ +
Sbjct: 279 QWLK-RVEYGAEGRHNS 294
Score = 48.4 bits (110), Expect = 5e-04
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R+ VE P W +DG + L + L + V DAGVY C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG----LKVKQVEREDAGVYVC 99
Query: 3342 TASNEVGRASTS-----------GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
A+N G S + GK E +G D +S + P P +P +R+
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGK-ESLGPDSSSGGQEDPASQQWARPRFTQPSKMRR- 157
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R G +V ++C G P+PD+ W++D
Sbjct: 158 RVIARPVGSSVRLKCVASGHPRPDITWMKD 187
Score = 41.1 bits (92), Expect = 0.068
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 3049 RPEFVDILPGQLKILA---GETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNG 3104
RP F + +++A G + L C G P P + WMK+ + EA +
Sbjct: 146 RPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKK--- 202
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L++K++ +D G+Y+C +N G + ++ V+
Sbjct: 203 -KWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor variant
protein.
Length = 1478
Score = 72.9 bits (171), Expect = 2e-11
Identities = 82/328 (25%), Positives = 119/328 (36%), Gaps = 34/328 (10%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDG---LITLE 2652
F+ D+T V G C P + W + G + N+ + DG ++ ++
Sbjct: 2 FTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQ 61
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
L P D A Y C N G IS S L V + PT +
Sbjct: 62 PLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTAT 120
Query: 2713 LECRIRGQPLPKITWFKDDKQIP---SDGRYQAFYLADGVCR--LAIDNPTPEDSGTYTC 2767
+ C G P P+ITWFKD + ++GR + R L I+ D G Y C
Sbjct: 121 MLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYEC 180
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
A NS G N+ E + R P F T++++ G
Sbjct: 181 VATNS------------AGTRYSAPANLYVRELREVRRVP-----PRFSIPPTNHEIMPG 223
Query: 2828 GTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCR 2886
G++ + G P V+W+ +T + G L L+DV +S YTC
Sbjct: 224 GSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELNDV--RQSANYTCV 276
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
A S G ++ A ITV G P V
Sbjct: 277 AMSTLGVIEAIAQITVKALPKPPGTPVV 304
Score = 66.5 bits (155), Expect = 2e-09
Identities = 76/309 (24%), Positives = 122/309 (39%), Gaps = 41/309 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 12 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 71
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 72 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 115
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT--------LEIAPTNLD 3233
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 116 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSGGTPIRGALQIEQSEES 173
Query: 3234 DGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELRISA 3289
D G YE A N++G S L V + +R V P F + P +++ G + I+
Sbjct: 174 DQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVNITC 230
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGR 3349
V P V W L P M + R+ L R + YTC A + +G
Sbjct: 231 VAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMSTLGV 283
Query: 3350 ASTSGKVEV 3358
++ V
Sbjct: 284 IEAIAQITV 292
Score = 57.2 bits (132), Expect = 1e-06
Identities = 63/240 (26%), Positives = 90/240 (37%), Gaps = 27/240 (11%)
Query: 3189 CQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQFHTLEIAPTNLD-DGGVYEVTARNNS 3246
CQ G P PK+ W K G++V + ++ D L I P D +YE A NN
Sbjct: 21 CQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNV 80
Query: 3247 GAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
G +S L V D+ R + + L+ + + L P +TW++
Sbjct: 81 GEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATML---CAASGNPDPEITWFK 137
Query: 3304 DGVRLRPSRR--AIMTLDRDGQ-IELALAAVTTR--DAGVYTCTASNEVGRASTSGKVEV 3358
D + + S I L G I AL + D G Y C A+N G S +
Sbjct: 138 DFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANL 196
Query: 3359 IGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
+ R+PP P P + E G +V I C VG P P V W+
Sbjct: 197 YVRELREVRRVPPRFSIP-------------PTNHEIMPGGSVNITCVAVGSPMPYVKWM 243
Score = 56.4 bits (130), Expect = 2e-06
Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 22/162 (13%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNG---FD 3106
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ +G
Sbjct: 104 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIR 162
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDY 3166
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 163 GALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVRR-V 207
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 208 PPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 249
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 27 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 86
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 87 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 130
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 131 PEITWFKDFLPV 142
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 209 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 262
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 263 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 292
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 72.5 bits (170), Expect = 2e-11
Identities = 86/366 (23%), Positives = 142/366 (38%), Gaps = 27/366 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 170 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 227
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ PED G Y C A+N + + V T ++ S N E
Sbjct: 228 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 278
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 279 -MKSRRPK-----SSPPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 330
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEK-DILI 2925
VT T+ TC W + V+ S+ K ++ GR E
Sbjct: 331 ESVELFGKVTGTQP--ITC-TWMKFRKQIQESEHMKVENSENGSKLTILAGRQEHCGCYT 387
Query: 2926 SVGEDINISFRTQGEPKPKAVPERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVE 2985
+ E+ + S + Q P+ G PC D ++ ++L+W S + V +Y +E
Sbjct: 388 LLVENKSGSRQAQVNLSVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 447
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 448 IW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 504
Query: 3046 AGDRPE 3051
+ P+
Sbjct: 505 KPEEPK 510
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 880 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 939
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 940 GNCSLIISDVCGDDDAKYTCKAVNSL 965
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 895 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 954
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 955 AKYTCKAVNSLGEATCTAELIVET 978
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 881 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 939
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 940 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 976
Score = 54.8 bits (126), Expect = 5e-06
Identities = 63/275 (22%), Positives = 105/275 (38%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 136 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 194
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ +D G Y C A N
Sbjct: 195 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALPEDRGLYKCVAKND 253
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 254 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSPPPVLGTESDATVKKKPAPKTPPKAA 313
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 314 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 373
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N SG+ L VVDK
Sbjct: 374 TILAGRQEHCGCYTLLVENKSGSRQAQVNLSVVDK 408
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 875 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 934
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 935 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 977
Score = 48.4 bits (110), Expect = 5e-04
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 165 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 222
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+P D Y C +N+ G S + V P+ E + P +R
Sbjct: 223 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 282
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 885 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 944
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 945 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 976
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 885 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 944
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 945 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 985
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 175 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 231
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 232 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 277
Score = 37.1 bits (82), Expect = 1.1
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 168 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 226
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 227 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 286
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+G + + + + + PK PK A+P +I
Sbjct: 287 SPPPVLGTESDATVKKKPAPKTPPKAAMPPQI 318
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 877 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 927
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 72.5 bits (170), Expect = 2e-11
Identities = 84/336 (25%), Positives = 127/336 (37%), Gaps = 37/336 (11%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAFYLADGVCRLAIDNPTP 2759
+ C G P P+ITWFKD + ++GR + ++ + L I+
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQL-RSESIGALQIEQSEE 193
Query: 2760 EDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVL 2819
D G Y C A NS T R S +P + R+ P F
Sbjct: 194 SDQGKYECVATNSAGT-----------RYS--APANLYVRVRRVP--------PRFSIPP 232
Query: 2820 TDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTET 2878
T++++ GG++ + G P V+W+ +T + G L L+DV
Sbjct: 233 TNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELNDV--R 285
Query: 2879 ESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
+S YTC A S G ++ A ITV G P V
Sbjct: 286 QSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 321
Score = 71.3 bits (167), Expect = 6e-11
Identities = 75/302 (24%), Positives = 119/302 (39%), Gaps = 34/302 (11%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK---RRNKYQDEQFHTLEIAPTNLDDGGVY 3238
T + C G+P P+++W+KD V R + + E L+I + D G Y
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKY 199
Query: 3239 EVTARNNSGA-VSCHCGLVVDKGIRAYVAPEFCCGLEPL-YKLHEGDELRISAVVEAYPS 3296
E A N++G S L V +R V P F + P +++ G + I+ V P
Sbjct: 200 ECVATNSAGTRYSAPANLYV--RVRR-VPPRF--SIPPTNHEIMPGGSVNITCVAVGSPM 254
Query: 3297 VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKV 3356
V W L P M + R+ L R + YTC A + +G ++
Sbjct: 255 PYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMSTLGVIEAIAQI 307
Query: 3357 EV 3358
V
Sbjct: 308 TV 309
Score = 62.5 bits (145), Expect = 3e-08
Identities = 67/264 (25%), Positives = 99/264 (37%), Gaps = 30/264 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRN-KYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + + L+ +
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVE 138
Query: 3278 KLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDGQIELALAAVTTRD 3335
+ L P +TW++D + + S I L + L + D
Sbjct: 139 RTRTATML---CAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESD 195
Query: 3336 AGVYTCTASNEVG-RASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSE 3394
G Y C A+N G R S + V R+PP P P + E
Sbjct: 196 QGKYECVATNSAGTRYSAPANLYV------RVRRVPPRFSIP-------------PTNHE 236
Query: 3395 AREGDTVIIECEVVGDPKPDVYWL 3418
G +V I C VG P P V W+
Sbjct: 237 IMPGGSVNITCVAVGSPMPYVKWM 260
Score = 52.8 bits (121), Expect = 2e-05
Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 23/159 (14%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRMTSQFNGFDCCL 3109
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + L
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGAL 186
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I+ D+G+Y C ATN+ G T + A A L R V PP+
Sbjct: 187 QIEQSEESDQGKYECVATNSAG--------------TRYSAPANLY-VRVRRV----PPR 227
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
F++ + + V +TC +GSP P V W E++
Sbjct: 228 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 266
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 226 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 279
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 280 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 309
>BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth factor
receptor-like 1 protein.
Length = 504
Score = 72.5 bits (170), Expect = 2e-11
Identities = 57/210 (27%), Positives = 88/210 (41%), Gaps = 16/210 (7%)
Query: 3050 PEFVD-ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
P+ D ++P Q+ L G T L C V+G P P +W K+G + R G
Sbjct: 29 PKMADKVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---- 83
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD----RTVWEADAKLKRERSAEVEG 3164
L +K + +D G Y C+ATN G S L V+ D + D+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQ 143
Query: 3165 DYPPQFTMRLRDRRVQATYP----VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
P+FT + RR P VRL C G P P ++W KD + + + + +
Sbjct: 144 WARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKK 203
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
TL + +D G Y N +GA++
Sbjct: 204 --WTLSLKNLRPEDSGKYTCRVSNRAGAIN 231
Score = 64.9 bits (151), Expect = 5e-09
Identities = 72/278 (25%), Positives = 110/278 (39%), Gaps = 48/278 (17%)
Query: 3167 PPQFTMRLRDRRV-QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP+ ++ R+V + VRL C V G PPP W KDG + R + + L
Sbjct: 28 PPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQ---GL 84
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI---RAYVAPEFCCG---------- 3272
++ +D GVY A N G++S + LVV I + + P+ G
Sbjct: 85 KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQW 144
Query: 3273 LEPLY----KLHE-------GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
P + K+ G +R+ V +P +TW +D L R R
Sbjct: 145 ARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRK 201
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ L+L + D+G YTC SN G + + KV+VI R PV+
Sbjct: 202 KKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI-----QRTRSKPVLTG------ 250
Query: 3382 KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
P ++ G T +C+V D KP + WL+
Sbjct: 251 ------THPVNTTVDFGGTTSFQCKVRSDVKPVIQWLK 282
Score = 57.2 bits (132), Expect = 1e-06
Identities = 64/273 (23%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 2681 LKVYPSFEASPIPPTFTRSI--RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG 2738
L +P A+ PP + R L + L+C + G P P W KD + I S G
Sbjct: 16 LGAFPPAAAARGPPKMADKVVPRQVARLGRT-VRLQCPVEGDPPPLTMWTKDGRTIHS-G 73
Query: 2739 RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT-----GRESQVSP 2793
+ L G L + ED+G Y CKA N + + + + G+ES + P
Sbjct: 74 WSRFRVLPQG---LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKES-LGP 129
Query: 2794 NVVTAEKTRIARQSLESRRPHFGNVLTDYQVAR--GGTIGLQVEIRGCPTR-VEWLREGR 2850
+ + + A Q R + + +AR G ++ L+ G P + W+++ +
Sbjct: 130 DSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQ 189
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
++T R + +TL+L ++ +SG YTCR + G ++ + V+Q +
Sbjct: 190 ALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--RS 244
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP V+ G + + G + + + + KP
Sbjct: 245 KP-VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Score = 52.8 bits (121), Expect = 2e-05
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNK--LKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V+L C P +TW ++ L + RKK TL + N P DS +Y+
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKW----TLSLKNLRPEDSGKYT 220
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C V N GAI+ + + V + P+ T T + T +C++R P I
Sbjct: 221 CRVSNRAGAINATYKVDVIQRTRSKPV-LTGTHPVNTTVDFG-GTTSFQCKVRSDVKPVI 278
Query: 2726 TWFKDDKQIPSDGRYQA 2742
W K + ++GR+ +
Sbjct: 279 QWLK-RVEYGAEGRHNS 294
Score = 48.4 bits (110), Expect = 5e-04
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R+ VE P W +DG + L + L + V DAGVY C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG----LKVKQVEREDAGVYVC 99
Query: 3342 TASNEVGRASTS-----------GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
A+N G S + GK E +G D +S + P P +P +R+
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGK-ESLGPDSSSGGQEDPASQQWARPRFTQPSKMRR- 157
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R G +V ++C G P+PD+ W++D
Sbjct: 158 RVIARPVGSSVRLKCVASGHPRPDITWMKD 187
Score = 41.1 bits (92), Expect = 0.068
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 3049 RPEFVDILPGQLKILA---GETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNG 3104
RP F + +++A G + L C G P P + WMK+ + EA +
Sbjct: 146 RPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKK--- 202
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L++K++ +D G+Y+C +N G + ++ V+
Sbjct: 203 -KWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239
>AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein.
Length = 1115
Score = 72.5 bits (170), Expect = 2e-11
Identities = 83/314 (26%), Positives = 129/314 (41%), Gaps = 38/314 (12%)
Query: 3060 LKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+++ G TA + C + + P V + +E G +G L I + + +D
Sbjct: 138 IEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPSGN---LQIVNASQED 194
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
EG Y C A N + + + +DR +++R + YPP+ +
Sbjct: 195 EGMYKCAAYNP---VTQEVKTSGSSDRL------RVRRSTAEAARIIYPPEAQTII---- 241
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVV-YDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C G PPP+V+W KDG V Y+K R + L I T+ +D G
Sbjct: 242 VTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN-----LLIDTTSEEDSGT 296
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
Y A N G V+ ++ + PE L L + G +++ V P
Sbjct: 297 YRCMADNGVGQPG---AAVILYNVQVFEPPEVTMELSQLV-IPWGQSAKLTCEVRGNPPP 352
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
V W R+ V L S+R + L R L + ++ D GVY C A NEVG A ++
Sbjct: 353 SVLWLRNAVPLISSQR--LRLSRRA---LRVLSMGPEDEGVYQCMAENEVGSAHAVVQL- 406
Query: 3358 VIGTDQTSEPRIPP 3371
+TS P I P
Sbjct: 407 -----RTSRPSITP 415
Score = 54.4 bits (125), Expect = 7e-06
Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query: 2651 LEVLNAVPSDSAEYSCTVEN----ENGAISTSANLKVYPSF-EASPIPPTFTRSIRDTFH 2705
L+++NA D Y C N E +S L+V S EA+ I + +
Sbjct: 185 LQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARI--IYPPEAQTIIV 242
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L+LEC G P P++TW KD + + + F L++ L ID + EDSGTY
Sbjct: 243 TKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTR-FLLSN----LLIDTTSEEDSGTY 297
Query: 2766 TCKAENSV 2773
C A+N V
Sbjct: 298 RCMADNGV 305
Score = 54.4 bits (125), Expect = 7e-06
Identities = 46/167 (27%), Positives = 63/167 (37%), Gaps = 13/167 (7%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+G + L C P VTW ++G + K R L + LI DS Y C
Sbjct: 244 KGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSNLLID----TTSEEDSGTYRC 299
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
+N G + L FE PP T + L C +RG P P +
Sbjct: 300 MADNGVGQPGAAVILYNVQVFE----PPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVL 355
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
W ++ + S R + A L + + PED G Y C AEN V
Sbjct: 356 WLRNAVPLISSQRLRLSRRA-----LRVLSMGPEDEGVYQCMAENEV 397
Score = 50.0 bits (114), Expect = 1e-04
Identities = 79/344 (22%), Positives = 130/344 (37%), Gaps = 43/344 (12%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLEVLNAVPSDSAEYSC 2666
G V L C V+ VTW NG L+ L+ G + + LN Y C
Sbjct: 50 GGTVILGC-VVEPPRMNVTWRLNGKELNGSDDALGVLITHGTLVITALNN--HTVGRYQC 106
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAE-NELVLECRI-RGQPLPK 2724
GA+++ + + F ++ + E N V+ C + P +
Sbjct: 107 VARMPAGAVASVPATVTLANLQ------DFKLDVQHVIEVDEGNTAVIACHLPESHPKAQ 160
Query: 2725 ITW-FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ + K + S G Y + G L I N + ED G Y C A N V T V
Sbjct: 161 VRYSVKQEWLEASRGNY--LIMPSG--NLQIVNASQEDEGMYKCAAYNPV-----TQEVK 211
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
+G ++++ R+ R + E+ R + V +G ++ L+ G P R
Sbjct: 212 TSG----------SSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPR 261
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V W ++G SVT Y R L L + +E +SG Y C A V A +
Sbjct: 262 VTWAKDGSSVTG-YNKTRFL----LSNLLIDTTSEEDSGTYRC---MADNGVGQPGAAVI 313
Query: 2903 VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
+ + P V + + ++I G+ ++ +G P P +
Sbjct: 314 LYNVQVFEPPEVTMELSQ--LVIPWGQSAKLTCEVRGNPPPSVL 355
Score = 48.4 bits (110), Expect = 5e-04
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 13/110 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCC 3108
P V + QL I G++A LTC V+G P P V+W++N + + R++ +
Sbjct: 322 PPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRR------A 375
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAV----VTDRTVWEADAKL 3154
L + + +DEG Y C A N G A +L +T R +W+ DA+L
Sbjct: 376 LRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRTSRPSITPR-LWQ-DAEL 423
Score = 44.4 bits (100), Expect = 0.007
Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G KLTC V + P+V W RN V L + + R L VL+ P D Y C
Sbjct: 337 GQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRL----SRRALRVLSMGPEDEGVYQCM 392
Query: 2668 VENENGAISTSANLK 2682
ENE G+ L+
Sbjct: 393 AENEVGSAHAVVQLR 407
Score = 39.1 bits (87), Expect = 0.28
Identities = 60/256 (23%), Positives = 108/256 (42%), Gaps = 27/256 (10%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLE 3226
PQ T++ + V L C V+ P V+W +G+E+ + + H TL
Sbjct: 36 PQVTVQPASTVQKPGGTVILGC-VVEPPRMNVTWRLNGKEL--NGSDDALGVLITHGTLV 92
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I N G Y+ AR +GAV+ V ++ +F ++ + ++ EG+
Sbjct: 93 ITALNNHTVGRYQCVARMPAGAVASVPATVTLANLQ-----DFKLDVQHVIEVDEGNTAV 147
Query: 3287 ISA-VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
I+ + E++P V + L SR + + G +++ A+ D G+Y C A N
Sbjct: 148 IACHLPESHPKAQVRYSVKQEWLEASRGNYLIMP-SGNLQIVNAS--QEDEGMYKCAAYN 204
Query: 3346 EVGR-ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
V + TSG + + + S ++ P+ + + + K G ++I+E
Sbjct: 205 PVTQEVKTSGSSDRLRV-RRSTAEAARIIYPPEA----QTIIVTK--------GQSLILE 251
Query: 3405 CEVVGDPKPDVYWLRD 3420
C G P P V W +D
Sbjct: 252 CVASGIPPPRVTWAKD 267
>AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein.
Length = 504
Score = 72.5 bits (170), Expect = 2e-11
Identities = 57/210 (27%), Positives = 88/210 (41%), Gaps = 16/210 (7%)
Query: 3050 PEFVD-ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
P+ D ++P Q+ L G T L C V+G P P +W K+G + R G
Sbjct: 29 PKMADKVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---- 83
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD----RTVWEADAKLKRERSAEVEG 3164
L +K + +D G Y C+ATN G S L V+ D + D+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQ 143
Query: 3165 DYPPQFTMRLRDRRVQATYP----VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
P+FT + RR P VRL C G P P ++W KD + + + + +
Sbjct: 144 WARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKK 203
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
TL + +D G Y N +GA++
Sbjct: 204 --WTLSLKNLRPEDSGKYTCRVSNRAGAIN 231
Score = 64.9 bits (151), Expect = 5e-09
Identities = 72/278 (25%), Positives = 110/278 (39%), Gaps = 48/278 (17%)
Query: 3167 PPQFTMRLRDRRV-QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP+ ++ R+V + VRL C V G PPP W KDG + R + + L
Sbjct: 28 PPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQ---GL 84
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI---RAYVAPEFCCG---------- 3272
++ +D GVY A N G++S + LVV I + + P+ G
Sbjct: 85 KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQW 144
Query: 3273 LEPLY----KLHE-------GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
P + K+ G +R+ V +P +TW +D L R R
Sbjct: 145 ARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRK 201
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ L+L + D+G YTC SN G + + KV+VI R PV+
Sbjct: 202 KKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI-----QRTRSKPVLTG------ 250
Query: 3382 KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
P ++ G T +C+V D KP + WL+
Sbjct: 251 ------THPVNTTVDFGGTTSFQCKVRSDVKPVIQWLK 282
Score = 57.2 bits (132), Expect = 1e-06
Identities = 64/273 (23%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 2681 LKVYPSFEASPIPPTFTRSI--RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG 2738
L +P A+ PP + R L + L+C + G P P W KD + I S G
Sbjct: 16 LGAFPPAAAARGPPKMADKVVPRQVARLGRT-VRLQCPVEGDPPPLTMWTKDGRTIHS-G 73
Query: 2739 RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT-----GRESQVSP 2793
+ L G L + ED+G Y CKA N + + + + G+ES + P
Sbjct: 74 WSRFRVLPQG---LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKES-LGP 129
Query: 2794 NVVTAEKTRIARQSLESRRPHFGNVLTDYQVAR--GGTIGLQVEIRGCPTR-VEWLREGR 2850
+ + + A Q R + + +AR G ++ L+ G P + W+++ +
Sbjct: 130 DSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQ 189
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
++T R + +TL+L ++ +SG YTCR + G ++ + V+Q +
Sbjct: 190 ALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--RS 244
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP V+ G + + G + + + + KP
Sbjct: 245 KP-VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Score = 52.8 bits (121), Expect = 2e-05
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNK--LKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V+L C P +TW ++ L + RKK TL + N P DS +Y+
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKW----TLSLKNLRPEDSGKYT 220
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C V N GAI+ + + V + P+ T T + T +C++R P I
Sbjct: 221 CRVSNRAGAINATYKVDVIQRTRSKPV-LTGTHPVNTTVDFG-GTTSFQCKVRSDVKPVI 278
Query: 2726 TWFKDDKQIPSDGRYQA 2742
W K + ++GR+ +
Sbjct: 279 QWLK-RVEYGAEGRHNS 294
Score = 48.4 bits (110), Expect = 5e-04
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R+ VE P W +DG + L + L + V DAGVY C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG----LKVKQVEREDAGVYVC 99
Query: 3342 TASNEVGRASTS-----------GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
A+N G S + GK E +G D +S + P P +P +R+
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGK-ESLGPDSSSGGQEDPASQQWARPRFTQPSKMRR- 157
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R G +V ++C G P+PD+ W++D
Sbjct: 158 RVIARPVGSSVRLKCVASGHPRPDITWMKD 187
Score = 41.1 bits (92), Expect = 0.068
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 3049 RPEFVDILPGQLKILA---GETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNG 3104
RP F + +++A G + L C G P P + WMK+ + EA +
Sbjct: 146 RPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKK--- 202
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L++K++ +D G+Y+C +N G + ++ V+
Sbjct: 203 -KWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239
>AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein.
Length = 1114
Score = 72.5 bits (170), Expect = 2e-11
Identities = 83/314 (26%), Positives = 129/314 (41%), Gaps = 38/314 (12%)
Query: 3060 LKILAGETANLTCSV-KGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+++ G TA + C + + P V + +E G +G L I + + +D
Sbjct: 138 IEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPSGN---LQIVNASQED 194
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
EG Y C A N + + + +DR +++R + YPP+ +
Sbjct: 195 EGMYKCAAYNP---VTQEVKTSGSSDRL------RVRRSTAEAARIIYPPEAQTII---- 241
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVV-YDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
V + L C G PPP+V+W KDG V Y+K R + L I T+ +D G
Sbjct: 242 VTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN-----LLIDTTSEEDSGT 296
Query: 3238 YEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
Y A N G V+ ++ + PE L L + G +++ V P
Sbjct: 297 YRCMADNGVGQPG---AAVILYNVQVFEPPEVTMELSQLV-IPWGQSAKLTCEVRGNPPP 352
Query: 3298 GVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVE 3357
V W R+ V L S+R + L R L + ++ D GVY C A NEVG A ++
Sbjct: 353 SVLWLRNAVPLISSQR--LRLSRRA---LRVLSMGPEDEGVYQCMAENEVGSAHAVVQL- 406
Query: 3358 VIGTDQTSEPRIPP 3371
+TS P I P
Sbjct: 407 -----RTSRPSITP 415
Score = 54.4 bits (125), Expect = 7e-06
Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query: 2651 LEVLNAVPSDSAEYSCTVEN----ENGAISTSANLKVYPSF-EASPIPPTFTRSIRDTFH 2705
L+++NA D Y C N E +S L+V S EA+ I + +
Sbjct: 185 LQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARI--IYPPEAQTIIV 242
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L+LEC G P P++TW KD + + + F L++ L ID + EDSGTY
Sbjct: 243 TKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTR-FLLSN----LLIDTTSEEDSGTY 297
Query: 2766 TCKAENSV 2773
C A+N V
Sbjct: 298 RCMADNGV 305
Score = 54.4 bits (125), Expect = 7e-06
Identities = 46/167 (27%), Positives = 63/167 (37%), Gaps = 13/167 (7%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSC 2666
+G + L C P VTW ++G + K R L + LI DS Y C
Sbjct: 244 KGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSNLLID----TTSEEDSGTYRC 299
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKIT 2726
+N G + L FE PP T + L C +RG P P +
Sbjct: 300 MADNGVGQPGAAVILYNVQVFE----PPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVL 355
Query: 2727 WFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
W ++ + S R + A L + + PED G Y C AEN V
Sbjct: 356 WLRNAVPLISSQRLRLSRRA-----LRVLSMGPEDEGVYQCMAENEV 397
Score = 50.0 bits (114), Expect = 1e-04
Identities = 79/344 (22%), Positives = 130/344 (37%), Gaps = 43/344 (12%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD-GLITLEVLNAVPSDSAEYSC 2666
G V L C V+ VTW NG L+ L+ G + + LN Y C
Sbjct: 50 GGTVILGC-VVEPPRMNVTWRLNGKELNGSDDALGVLITHGTLVITALNN--HTVGRYQC 106
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAE-NELVLECRI-RGQPLPK 2724
GA+++ + + F ++ + E N V+ C + P +
Sbjct: 107 VARMPAGAVASVPATVTLANLQ------DFKLDVQHVIEVDEGNTAVIACHLPESHPKAQ 160
Query: 2725 ITW-FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
+ + K + S G Y + G L I N + ED G Y C A N V T V
Sbjct: 161 VRYSVKQEWLEASRGNY--LIMPSG--NLQIVNASQEDEGMYKCAAYNPV-----TQEVK 211
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
+G ++++ R+ R + E+ R + V +G ++ L+ G P R
Sbjct: 212 TSG----------SSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPR 261
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V W ++G SVT Y R L L + +E +SG Y C A V A +
Sbjct: 262 VTWAKDGSSVTG-YNKTRFL----LSNLLIDTTSEEDSGTYRC---MADNGVGQPGAAVI 313
Query: 2903 VQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAV 2946
+ + P V + + ++I G+ ++ +G P P +
Sbjct: 314 LYNVQVFEPPEVTMELSQ--LVIPWGQSAKLTCEVRGNPPPSVL 355
Score = 48.4 bits (110), Expect = 5e-04
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 13/110 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHE-VEEEAGRMTSQFNGFDCC 3108
P V + QL I G++A LTC V+G P P V+W++N + + R++ +
Sbjct: 322 PPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRR------A 375
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAV----VTDRTVWEADAKL 3154
L + + +DEG Y C A N G A +L +T R +W+ DA+L
Sbjct: 376 LRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRTSRPSITPR-LWQ-DAEL 423
Score = 44.4 bits (100), Expect = 0.007
Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G KLTC V + P+V W RN V L + + R L VL+ P D Y C
Sbjct: 337 GQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRL----SRRALRVLSMGPEDEGVYQCM 392
Query: 2668 VENENGAISTSANLK 2682
ENE G+ L+
Sbjct: 393 AENEVGSAHAVVQLR 407
Score = 39.1 bits (87), Expect = 0.28
Identities = 60/256 (23%), Positives = 108/256 (42%), Gaps = 27/256 (10%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFH-TLE 3226
PQ T++ + V L C V+ P V+W +G+E+ + + H TL
Sbjct: 36 PQVTVQPASTVQKPGGTVILGC-VVEPPRMNVTWRLNGKEL--NGSDDALGVLITHGTLV 92
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELR 3286
I N G Y+ AR +GAV+ V ++ +F ++ + ++ EG+
Sbjct: 93 ITALNNHTVGRYQCVARMPAGAVASVPATVTLANLQ-----DFKLDVQHVIEVDEGNTAV 147
Query: 3287 ISA-VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASN 3345
I+ + E++P V + L SR + + G +++ A+ D G+Y C A N
Sbjct: 148 IACHLPESHPKAQVRYSVKQEWLEASRGNYLIMP-SGNLQIVNAS--QEDEGMYKCAAYN 204
Query: 3346 EVGR-ASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
V + TSG + + + S ++ P+ + + + K G ++I+E
Sbjct: 205 PVTQEVKTSGSSDRLRV-RRSTAEAARIIYPPEA----QTIIVTK--------GQSLILE 251
Query: 3405 CEVVGDPKPDVYWLRD 3420
C G P P V W +D
Sbjct: 252 CVASGIPPPRVTWAKD 267
>AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfamily,
member 9 protein.
Length = 1179
Score = 72.5 bits (170), Expect = 2e-11
Identities = 93/378 (24%), Positives = 146/378 (38%), Gaps = 67/378 (17%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P+F + P L++ E L C +G P+P V W G ++ + G++ Q NG L
Sbjct: 136 PQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQ-NG---TL 191
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I+ + G Y+C+A++T G A+ +L V+ PP
Sbjct: 192 RIRRVERGSSGVYTCQASSTEGSATHATQLLVLG-----------------------PPV 228
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPP-KVSWYKDGEEVVYDKR-RNKYQDEQFHTLEI 3227
+ ++ V A+ V L C P SW++D V + R + + + +L +
Sbjct: 229 IVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRL 288
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA---PEFCCGLEPLYKLHEGDE 3284
T DD G Y N GL+ AY+ P + P L G
Sbjct: 289 LATQPDDAGCYTCVPSN---------GLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMP 339
Query: 3285 LRISAVVEAYPS-VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA-GVYTCT 3342
I V A P + V+W +DG L+ + + +G + +AL DA G Y+CT
Sbjct: 340 GVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALG---NEDALGEYSCT 396
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE-GDTV 3401
N +G A S V+ P FI +P+ +E G +
Sbjct: 397 PYNSLGTAGPSPVTRVL--------------------LKAPPAFIERPKEEYFQEVGREL 436
Query: 3402 IIECEVVGDPKPDVYWLR 3419
+I C GDP P V W +
Sbjct: 437 LIPCSAQGDPPPVVSWTK 454
Score = 59.3 bits (137), Expect = 2e-07
Identities = 63/222 (28%), Positives = 86/222 (38%), Gaps = 12/222 (5%)
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPK-VSWYKDGEEVVYDKRRNKYQDEQFHT 3224
YP Q T + + P + C V +PP VSW KDG+ + DK Q + +
Sbjct: 321 YPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTE-GS 379
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
L IA N D G Y T N+ G G + P F + Y G E
Sbjct: 380 LIIALGNEDALGEYSCTPYNSLGTA----GPSPVTRVLLKAPPAFIERPKEEYFQEVGRE 435
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
L I + P V+W + G L+ + D L L +T G + C+AS
Sbjct: 436 LLIPCSAQGDPPPVVSWTKVGRGLQGQAQV------DSNSSLILRPLTKEAHGHWECSAS 489
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF 3386
N V R +TS V V+GT + V + S EP F
Sbjct: 490 NAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGF 531
Score = 52.4 bits (120), Expect = 3e-05
Identities = 53/187 (28%), Positives = 81/187 (43%), Gaps = 24/187 (12%)
Query: 3167 PPQFTMRLRD-RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQF VQ PV L C GSP P V+W G+++ + + + Q+ TL
Sbjct: 135 PPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQN---GTL 191
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I GVY A + G+ + H ++ G V P ++ ++
Sbjct: 192 RIRRVERGSSGVYTCQASSTEGSAT-HATQLLVLGPPVIVVP------PKNSTVNASQDV 244
Query: 3286 RISAVVEAYP-SVGVTWYRDGV------RLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
++ EAYP ++ +W++D + RL+P R ++ DG L L A DAG
Sbjct: 245 SLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILV----DG--SLRLLATQPDDAGC 298
Query: 3339 YTCTASN 3345
YTC SN
Sbjct: 299 YTCVPSN 305
Score = 45.2 bits (102), Expect = 0.004
Identities = 72/336 (21%), Positives = 123/336 (36%), Gaps = 44/336 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
V L C S P VTW G L + + ++ +G TL + S Y+C +
Sbjct: 154 VTLRCVARGSPLPHVTWKLRGKDLGQG-QGQVQVQNG--TLRIRRVERGSSGVYTCQASS 210
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP-KITWFK 2729
G+ + + L V PP +++ A ++ L C P +WF+
Sbjct: 211 TEGSATHATQLLVLG-------PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQ 263
Query: 2730 DDKQIPSDGRYQ--AFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
D+ + R Q L DG RL P +D+G YTC N +
Sbjct: 264 DNINVFHISRLQPRVRILVDGSLRLLATQP--DDAGCYTCVPSNGL-------------- 307
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLR 2847
+ P +A T + + + P T + G I V V W +
Sbjct: 308 ---LHPPSASAYLTVLYPAQVTAMPPE-----TPLPIGMPGVIRCPVRANPPLLFVSWTK 359
Query: 2848 EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD 2907
+G+++ +G +AL + E G Y+C +++ G + V+ +
Sbjct: 360 DGKALQLDKFPGWSQGTEGSLIIALGN--EDALGEYSCTPYNSLGTAGPSPVTRVLLKA- 416
Query: 2908 LDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
P + RP+++ VG ++ I QG+P P
Sbjct: 417 ----PPAFIERPKEEYFQEVGRELLIPCSAQGDPPP 448
Score = 41.5 bits (93), Expect = 0.052
Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 15/187 (8%)
Query: 2625 VTWYRNGVLLD-NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
V+W ++G L +K + +G + + + N EYSCT N G S +V
Sbjct: 355 VSWTKDGKALQLDKFPGWSQGTEGSLIIALGNE--DALGEYSCTPYNSLGTAGPSPVTRV 412
Query: 2684 YPSFEASPIPPTFT-RSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA 2742
PP F R + F EL++ C +G P P ++W K + + G+ Q
Sbjct: 413 LLK-----APPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGL--QGQAQ- 464
Query: 2743 FYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
D L + T E G + C A N+V + V G V NV +
Sbjct: 465 ---VDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPK 521
Query: 2803 IARQSLE 2809
A S E
Sbjct: 522 GANVSWE 528
Score = 36.7 bits (81), Expect = 1.5
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + + E E V L C RG PLP +TW K + G+ Q + +G R
Sbjct: 135 PPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDL-GQGQGQV-QVQNGTLR 192
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
I SG YTC+A ++
Sbjct: 193 --IRRVERGSSGVYTCQASST 211
>AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor
receptor protein.
Length = 497
Score = 72.5 bits (170), Expect = 2e-11
Identities = 57/210 (27%), Positives = 88/210 (41%), Gaps = 16/210 (7%)
Query: 3050 PEFVD-ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCC 3108
P+ D ++P Q+ L G T L C V+G P P +W K+G + R G
Sbjct: 29 PKMADKVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---- 83
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTD----RTVWEADAKLKRERSAEVEG 3164
L +K + +D G Y C+ATN G S L V+ D + D+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQ 143
Query: 3165 DYPPQFTMRLRDRRVQATYP----VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
P+FT + RR P VRL C G P P ++W KD + + + + +
Sbjct: 144 WARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKK 203
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVS 3250
TL + +D G Y N +GA++
Sbjct: 204 --WTLSLKNLRPEDSGKYTCRVSNRAGAIN 231
Score = 64.9 bits (151), Expect = 5e-09
Identities = 72/278 (25%), Positives = 110/278 (39%), Gaps = 48/278 (17%)
Query: 3167 PPQFTMRLRDRRV-QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP+ ++ R+V + VRL C V G PPP W KDG + R + + L
Sbjct: 28 PPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQ---GL 84
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGI---RAYVAPEFCCG---------- 3272
++ +D GVY A N G++S + LVV I + + P+ G
Sbjct: 85 KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQW 144
Query: 3273 LEPLY----KLHE-------GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
P + K+ G +R+ V +P +TW +D L R R
Sbjct: 145 ARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRK 201
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYS 3381
+ L+L + D+G YTC SN G + + KV+VI R PV+
Sbjct: 202 KKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI-----QRTRSKPVLTG------ 250
Query: 3382 KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
P ++ G T +C+V D KP + WL+
Sbjct: 251 ------THPVNTTVDFGGTTSFQCKVRSDVKPVIQWLK 282
Score = 57.2 bits (132), Expect = 1e-06
Identities = 64/273 (23%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 2681 LKVYPSFEASPIPPTFTRSI--RDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG 2738
L +P A+ PP + R L + L+C + G P P W KD + I S G
Sbjct: 16 LGAFPPAAAARGPPKMADKVVPRQVARLGRT-VRLQCPVEGDPPPLTMWTKDGRTIHS-G 73
Query: 2739 RYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFT-----GRESQVSP 2793
+ L G L + ED+G Y CKA N + + + + G+ES + P
Sbjct: 74 WSRFRVLPQG---LKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKES-LGP 129
Query: 2794 NVVTAEKTRIARQSLESRRPHFGNVLTDYQVAR--GGTIGLQVEIRGCPTR-VEWLREGR 2850
+ + + A Q R + + +AR G ++ L+ G P + W+++ +
Sbjct: 130 DSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQ 189
Query: 2851 SVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDG 2910
++T R + +TL+L ++ +SG YTCR + G ++ + V+Q +
Sbjct: 190 ALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--RS 244
Query: 2911 KPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
KP V+ G + + G + + + + KP
Sbjct: 245 KP-VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Score = 52.8 bits (121), Expect = 2e-05
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNK--LKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V+L C P +TW ++ L + RKK TL + N P DS +Y+
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKW----TLSLKNLRPEDSGKYT 220
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C V N GAI+ + + V + P+ T T + T +C++R P I
Sbjct: 221 CRVSNRAGAINATYKVDVIQRTRSKPV-LTGTHPVNTTVDFG-GTTSFQCKVRSDVKPVI 278
Query: 2726 TWFKDDKQIPSDGRYQA 2742
W K + ++GR+ +
Sbjct: 279 QWLK-RVEYGAEGRHNS 294
Score = 48.4 bits (110), Expect = 5e-04
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R+ VE P W +DG + L + L + V DAGVY C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG----LKVKQVEREDAGVYVC 99
Query: 3342 TASNEVGRASTS-----------GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
A+N G S + GK E +G D +S + P P +P +R+
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGK-ESLGPDSSSGGQEDPASQQWARPRFTQPSKMRR- 157
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R G +V ++C G P+PD+ W++D
Sbjct: 158 RVIARPVGSSVRLKCVASGHPRPDITWMKD 187
Score = 41.1 bits (92), Expect = 0.068
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 3049 RPEFVDILPGQLKILA---GETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNG 3104
RP F + +++A G + L C G P P + WMK+ + EA +
Sbjct: 146 RPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKK--- 202
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L++K++ +D G+Y+C +N G + ++ V+
Sbjct: 203 -KWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239
>AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein.
Length = 1189
Score = 72.5 bits (170), Expect = 2e-11
Identities = 93/378 (24%), Positives = 146/378 (38%), Gaps = 67/378 (17%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P+F + P L++ E L C +G P+P V W G ++ + G++ Q NG L
Sbjct: 146 PQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQ-NG---TL 201
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
I+ + G Y+C+A++T G A+ +L V+ PP
Sbjct: 202 RIRRVERGSSGVYTCQASSTEGSATHATQLLVLG-----------------------PPV 238
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPP-KVSWYKDGEEVVYDKR-RNKYQDEQFHTLEI 3227
+ ++ V A+ V L C P SW++D V + R + + + +L +
Sbjct: 239 IVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRL 298
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA---PEFCCGLEPLYKLHEGDE 3284
T DD G Y N GL+ AY+ P + P L G
Sbjct: 299 LATQPDDAGCYTCVPSN---------GLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMP 349
Query: 3285 LRISAVVEAYPS-VGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDA-GVYTCT 3342
I V A P + V+W +DG L+ + + +G + +AL DA G Y+CT
Sbjct: 350 GVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALG---NEDALGEYSCT 406
Query: 3343 ASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE-GDTV 3401
N +G A S V+ P FI +P+ +E G +
Sbjct: 407 PYNSLGTAGPSPVTRVL--------------------LKAPPAFIERPKEEYFQEVGREL 446
Query: 3402 IIECEVVGDPKPDVYWLR 3419
+I C GDP P V W +
Sbjct: 447 LIPCSAQGDPPPVVSWTK 464
Score = 59.3 bits (137), Expect = 2e-07
Identities = 63/222 (28%), Positives = 86/222 (38%), Gaps = 12/222 (5%)
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPK-VSWYKDGEEVVYDKRRNKYQDEQFHT 3224
YP Q T + + P + C V +PP VSW KDG+ + DK Q + +
Sbjct: 331 YPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTE-GS 389
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
L IA N D G Y T N+ G G + P F + Y G E
Sbjct: 390 LIIALGNEDALGEYSCTPYNSLGTA----GPSPVTRVLLKAPPAFIERPKEEYFQEVGRE 445
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
L I + P V+W + G L+ + D L L +T G + C+AS
Sbjct: 446 LLIPCSAQGDPPPVVSWTKVGRGLQGQAQV------DSNSSLILRPLTKEAHGHWECSAS 499
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMF 3386
N V R +TS V V+GT + V + S EP F
Sbjct: 500 NAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGF 541
Score = 52.4 bits (120), Expect = 3e-05
Identities = 53/187 (28%), Positives = 81/187 (43%), Gaps = 24/187 (12%)
Query: 3167 PPQFTMRLRD-RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQF VQ PV L C GSP P V+W G+++ + + + Q+ TL
Sbjct: 145 PPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQN---GTL 201
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDEL 3285
I GVY A + G+ + H ++ G V P ++ ++
Sbjct: 202 RIRRVERGSSGVYTCQASSTEGSAT-HATQLLVLGPPVIVVP------PKNSTVNASQDV 254
Query: 3286 RISAVVEAYP-SVGVTWYRDGV------RLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
++ EAYP ++ +W++D + RL+P R ++ DG L L A DAG
Sbjct: 255 SLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILV----DG--SLRLLATQPDDAGC 308
Query: 3339 YTCTASN 3345
YTC SN
Sbjct: 309 YTCVPSN 315
Score = 45.2 bits (102), Expect = 0.004
Identities = 72/336 (21%), Positives = 123/336 (36%), Gaps = 44/336 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVEN 2670
V L C S P VTW G L + + ++ +G TL + S Y+C +
Sbjct: 164 VTLRCVARGSPLPHVTWKLRGKDLGQG-QGQVQVQNG--TLRIRRVERGSSGVYTCQASS 220
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP-KITWFK 2729
G+ + + L V PP +++ A ++ L C P +WF+
Sbjct: 221 TEGSATHATQLLVLG-------PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQ 273
Query: 2730 DDKQIPSDGRYQ--AFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
D+ + R Q L DG RL P +D+G YTC N +
Sbjct: 274 DNINVFHISRLQPRVRILVDGSLRLLATQP--DDAGCYTCVPSNGL-------------- 317
Query: 2788 ESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLR 2847
+ P +A T + + + P T + G I V V W +
Sbjct: 318 ---LHPPSASAYLTVLYPAQVTAMPPE-----TPLPIGMPGVIRCPVRANPPLLFVSWTK 369
Query: 2848 EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSD 2907
+G+++ +G +AL + E G Y+C +++ G + V+ +
Sbjct: 370 DGKALQLDKFPGWSQGTEGSLIIALGN--EDALGEYSCTPYNSLGTAGPSPVTRVLLKA- 426
Query: 2908 LDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
P + RP+++ VG ++ I QG+P P
Sbjct: 427 ----PPAFIERPKEEYFQEVGRELLIPCSAQGDPPP 458
Score = 41.5 bits (93), Expect = 0.052
Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 15/187 (8%)
Query: 2625 VTWYRNGVLLD-NKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
V+W ++G L +K + +G + + + N EYSCT N G S +V
Sbjct: 365 VSWTKDGKALQLDKFPGWSQGTEGSLIIALGNE--DALGEYSCTPYNSLGTAGPSPVTRV 422
Query: 2684 YPSFEASPIPPTFT-RSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQA 2742
PP F R + F EL++ C +G P P ++W K + + G+ Q
Sbjct: 423 LLK-----APPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGL--QGQAQ- 474
Query: 2743 FYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTR 2802
D L + T E G + C A N+V + V G V NV +
Sbjct: 475 ---VDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPK 531
Query: 2803 IARQSLE 2809
A S E
Sbjct: 532 GANVSWE 538
Score = 36.7 bits (81), Expect = 1.5
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCR 2751
PP F + + E E V L C RG PLP +TW K + G+ Q + +G R
Sbjct: 145 PPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDL-GQGQGQV-QVQNGTLR 202
Query: 2752 LAIDNPTPEDSGTYTCKAENS 2772
I SG YTC+A ++
Sbjct: 203 --IRRVERGSSGVYTCQASST 221
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 72.1 bits (169), Expect = 3e-11
Identities = 75/313 (23%), Positives = 115/313 (36%), Gaps = 39/313 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P + W+ NG +E + + +G + ++
Sbjct: 348 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQE 405
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y C A+N +G A + V+ AE P T+
Sbjct: 406 RSSAVYQCNASNEYGYLLANAFVNVL-----------------AEPPRILTPANTLY--- 445
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+V A P L C GSP P + W+K + + + Y + TLEI D G
Sbjct: 446 -QVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIPVAQKDSTG 502
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y ARN G L + PE+ + G + V+ +
Sbjct: 503 TYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAV-------VQRGSMVSFECKVKHDHT 555
Query: 3297 VGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
+ +T W +D L R T+D+D L +A V+ D+G YTC A+ + S S
Sbjct: 556 LSLTVLWLKDNRELPSDER--FTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASA 610
Query: 3355 KVEVIGTDQTSEP 3367
+ V+ T P
Sbjct: 611 VLSVVAPTPTPAP 623
Score = 71.7 bits (168), Expect = 4e-11
Identities = 84/343 (24%), Positives = 137/343 (39%), Gaps = 45/343 (13%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T+S P + T + G L C + P ++W NGV ++ +
Sbjct: 333 TISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 392
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
+DG T+ N SA Y C NE G + +A + V PP +
Sbjct: 393 IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE------PPRILTPANTLY 445
Query: 2705 HLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+ N +L+C G PLP I WFK K ++ Y+ L I + +G
Sbjct: 446 QVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTG 502
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TYTC A N + +++V + A T I +Q P +
Sbjct: 503 TYTCVARNKLGM-----------AKNEVHLEIKDA--TWIVKQ------PEYA------V 537
Query: 2824 VARGGTIGLQVEIRGCPT---RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V RG + + +++ T V WL++ R E+ + R V++ L ++DV++ +S
Sbjct: 538 VQRGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKD--HLVVADVSDDDS 592
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G YTC A + +V +A ++VV P+ P V P D+
Sbjct: 593 GTYTCVANTTLDSVSASAVLSVVAPTPTPA-PVYDVPNPPFDL 634
Score = 68.1 bits (159), Expect = 5e-10
Identities = 92/345 (26%), Positives = 143/345 (41%), Gaps = 47/345 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-----YS 2665
+ + C P+ +W RNG D + G TL ++N + AE Y
Sbjct: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL-IINIMSEGKAETYEGVYQ 122
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
CT NE GA + S N+ V PS P +T+ + L + LVL CR G P P
Sbjct: 123 CTARNERGA-AVSNNIVVRPSRS-----PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPP 176
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAE-NSVWTDQITH 2780
I W + Q +P R D L N PED+ Y C A N T Q
Sbjct: 177 IIFWMDNSFQRLPQSERVSQGLNGD----LYFSNVLPEDTREDYICYARFNHTQTIQ--- 229
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ +S V++A+ +R + + GN ++ + RG + L+ G P
Sbjct: 230 ------QKQPISVKVISAKSSRERPPTFLTPE---GNA-SNKEELRGNVLSLECIAEGLP 279
Query: 2841 TRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W +E + +N V+ + TL + V+E +SG Y C A +A G + +
Sbjct: 280 TPIIYWAKEDGMLP---KNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTIS 335
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V K A +++++S GED + R G PKP+
Sbjct: 336 VRV--------KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 372
Score = 55.6 bits (128), Expect = 3e-06
Identities = 85/369 (23%), Positives = 146/369 (39%), Gaps = 61/369 (16%)
Query: 3060 LKILAGETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + +G++ L C G P P + WM N + ++ R++ NG D + + D
Sbjct: 155 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG-DLYFS-NVLPEDT 212
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM---RLR 3175
Y C A H T + ++ + + AK RER PP F
Sbjct: 213 REDYICYARFNH--TQTIQQKQPISVKVI---SAKSSRER--------PPTFLTPEGNAS 259
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
++ + L C G P P + W K E+ + K R Y++ + TL+I + D
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAK--EDGMLPKNRTVYKNFE-KTLQIIHVSEADS 316
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y+ A+N GA+ H + +R AP + + L L G++ + P
Sbjct: 317 GNYQCIAKNALGAI--HHTI----SVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNP 369
Query: 3296 SVGVTWYRDGVRLR-----PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
++W +GV + PSR+ +D D + + V R + VY C ASNE G
Sbjct: 370 KPRISWLTNGVPIEIAPDDPSRK----IDGD---TIIFSNVQERSSAVYQCNASNEYGYL 422
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V V+ PP +++P + + +P +++C G
Sbjct: 423 LANAFVNVLAE--------PPRILTP--ANTLYQVIANRP----------ALLDCAFFGS 462
Query: 3411 PKPDVYWLR 3419
P P + W +
Sbjct: 463 PLPTIEWFK 471
Score = 50.0 bits (114), Expect = 1e-04
Identities = 80/324 (24%), Positives = 130/324 (40%), Gaps = 55/324 (16%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLT------DRTAVEGSRVKLTCSVISSSDPTVTWY 2628
+ + IS K +++S +P TFLT ++ + G+ + L C P + W
Sbjct: 229 QQKQPISVKVISAKSSRERP--PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA 286
Query: 2629 R-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
+ +G+L N+ Y+ TL++++ +DS Y C +N GAI + +++V
Sbjct: 287 KEDGMLPKNRTVYKNFEK----TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV---- 338
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFY 2744
+A+P T +++ E+ ++ CR G P P+I+W + I P D +
Sbjct: 339 KAAPYWITAPQNL--VLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRK--- 392
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
DG + N S Y C A N FVN V AE RI
Sbjct: 393 -IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVN------------VLAEPPRIL 438
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
+ N L YQV L G P +EW + G + ++ + V
Sbjct: 439 TPA---------NTL--YQVIANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLH 486
Query: 2864 EQGLYTLALSDVTETESGLYTCRA 2887
E G TL + + +G YTC A
Sbjct: 487 ENG--TLEIPVAQKDSTGTYTCVA 508
Score = 48.0 bits (109), Expect = 6e-04
Identities = 79/310 (25%), Positives = 124/310 (40%), Gaps = 44/310 (14%)
Query: 2604 TAVEGSRVKLTCSV-ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVLNAVPSDS 2661
T G + L C I P + W N +L +++ GL L N +P D+
Sbjct: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSF---QRLPQSERVSQGLNGDLYFSNVLPEDT 212
Query: 2662 AE-YSCTVE-NENGAISTSA--NLKVYPSFEASPIPPTFTR---SIRDTFHLAENELVLE 2714
E Y C N I ++KV + + PPTF + + L N L LE
Sbjct: 213 REDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLE 272
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGR-YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C G P P I W K+D +P + Y+ F L I + + DSG Y C A+N++
Sbjct: 273 CIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-----LQIIHVSEADSGNYQCIAKNAL 327
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
I H ++ + +P +TA Q+L VL+ GT+ +
Sbjct: 328 --GAIHHTISV---RVKAAPYWITAP------QNL---------VLSP---GEDGTLICR 364
Query: 2834 VEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
P R+ WL G + + ++ T+ S+V E S +Y C A + +G
Sbjct: 365 ANGNPKP-RISWLTNGVPIEIAPDDPSRKIDGD--TIIFSNVQERSSAVYQCNASNEYGY 421
Query: 2894 VDMNAAITVV 2903
+ NA + V+
Sbjct: 422 LLANAFVNVL 431
Score = 46.8 bits (106), Expect = 0.001
Identities = 67/267 (25%), Positives = 100/267 (37%), Gaps = 36/267 (13%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP T + +D + + + C+ G PPP SW ++G DK TL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 3226 EIAPTNLDDG------GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
I + +G GVY+ TARN GA + +VV E LEP+ L
Sbjct: 105 II--NIMSEGKAETYEGVYQCTARNERGAAVSN-NIVVRPSRSPLWTKE---KLEPI-TL 157
Query: 3280 HEGDELRISAVVEAYPSVG-----VTWYRDGV-RLRPSRRAIMTLDRDGQIELALAAVTT 3333
G L V+ P +G + W + RL S R L+ D L T
Sbjct: 158 QSGQSL----VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTR 213
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
D Y + + V+VI + E PP ++P+ S +
Sbjct: 214 EDYICYARFNHTQTIQQKQPISVKVISAKSSRER--PPTFLTPEGNAS----------NK 261
Query: 3394 EAREGDTVIIECEVVGDPKPDVYWLRD 3420
E G+ + +EC G P P +YW ++
Sbjct: 262 EELRGNVLSLECIAEGLPTPIIYWAKE 288
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 72.1 bits (169), Expect = 3e-11
Identities = 75/313 (23%), Positives = 115/313 (36%), Gaps = 39/313 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P + W+ NG +E + + +G + ++
Sbjct: 348 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQE 405
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y C A+N +G A + V+ AE P T+
Sbjct: 406 RSSAVYQCNASNEYGYLLANAFVNVL-----------------AEPPRILTPANTLY--- 445
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+V A P L C GSP P + W+K + + + Y + TLEI D G
Sbjct: 446 -QVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIPVAQKDSTG 502
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y ARN G L + PE+ + G + V+ +
Sbjct: 503 TYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAV-------VQRGSMVSFECKVKHDHT 555
Query: 3297 VGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
+ +T W +D L R T+D+D L +A V+ D+G YTC A+ + S S
Sbjct: 556 LSLTVLWLKDNRELPSDER--FTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASA 610
Query: 3355 KVEVIGTDQTSEP 3367
+ V+ T P
Sbjct: 611 VLSVVAPTPTPAP 623
Score = 71.7 bits (168), Expect = 4e-11
Identities = 84/343 (24%), Positives = 137/343 (39%), Gaps = 45/343 (13%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T+S P + T + G L C + P ++W NGV ++ +
Sbjct: 333 TISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 392
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
+DG T+ N SA Y C NE G + +A + V PP +
Sbjct: 393 IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE------PPRILTPANTLY 445
Query: 2705 HLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+ N +L+C G PLP I WFK K ++ Y+ L I + +G
Sbjct: 446 QVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTG 502
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TYTC A N + +++V + A T I +Q P +
Sbjct: 503 TYTCVARNKLGM-----------AKNEVHLEIKDA--TWIVKQ------PEYA------V 537
Query: 2824 VARGGTIGLQVEIRGCPT---RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V RG + + +++ T V WL++ R E+ + R V++ L ++DV++ +S
Sbjct: 538 VQRGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKD--HLVVADVSDDDS 592
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G YTC A + +V +A ++VV P+ P V P D+
Sbjct: 593 GTYTCVANTTLDSVSASAVLSVVAPTPTPA-PVYDVPNPPFDL 634
Score = 68.1 bits (159), Expect = 5e-10
Identities = 92/345 (26%), Positives = 143/345 (41%), Gaps = 47/345 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-----YS 2665
+ + C P+ +W RNG D + G TL ++N + AE Y
Sbjct: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL-IINIMSEGKAETYEGVYQ 122
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
CT NE GA + S N+ V PS P +T+ + L + LVL CR G P P
Sbjct: 123 CTARNERGA-AVSNNIVVRPSRS-----PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPP 176
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAE-NSVWTDQITH 2780
I W + Q +P R D L N PED+ Y C A N T Q
Sbjct: 177 IIFWMDNSFQRLPQSERVSQGLNGD----LYFSNVLPEDTREDYICYARFNHTQTIQ--- 229
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ +S V++A+ +R + + GN ++ + RG + L+ G P
Sbjct: 230 ------QKQPISVKVISAKSSRERPPTFLTPE---GNA-SNKEELRGNVLSLECIAEGLP 279
Query: 2841 TRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W +E + +N V+ + TL + V+E +SG Y C A +A G + +
Sbjct: 280 TPIIYWAKEDGMLP---KNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTIS 335
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V K A +++++S GED + R G PKP+
Sbjct: 336 VRV--------KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 372
Score = 55.6 bits (128), Expect = 3e-06
Identities = 85/369 (23%), Positives = 146/369 (39%), Gaps = 61/369 (16%)
Query: 3060 LKILAGETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + +G++ L C G P P + WM N + ++ R++ NG D + + D
Sbjct: 155 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG-DLYFS-NVLPEDT 212
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM---RLR 3175
Y C A H T + ++ + + AK RER PP F
Sbjct: 213 REDYICYARFNH--TQTIQQKQPISVKVI---SAKSSRER--------PPTFLTPEGNAS 259
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
++ + L C G P P + W K E+ + K R Y++ + TL+I + D
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAK--EDGMLPKNRTVYKNFE-KTLQIIHVSEADS 316
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y+ A+N GA+ H + +R AP + + L L G++ + P
Sbjct: 317 GNYQCIAKNALGAI--HHTI----SVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNP 369
Query: 3296 SVGVTWYRDGVRLR-----PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
++W +GV + PSR+ +D D + + V R + VY C ASNE G
Sbjct: 370 KPRISWLTNGVPIEIAPDDPSRK----IDGD---TIIFSNVQERSSAVYQCNASNEYGYL 422
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V V+ PP +++P + + +P +++C G
Sbjct: 423 LANAFVNVLAE--------PPRILTP--ANTLYQVIANRP----------ALLDCAFFGS 462
Query: 3411 PKPDVYWLR 3419
P P + W +
Sbjct: 463 PLPTIEWFK 471
Score = 50.0 bits (114), Expect = 1e-04
Identities = 80/324 (24%), Positives = 130/324 (40%), Gaps = 55/324 (16%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLT------DRTAVEGSRVKLTCSVISSSDPTVTWY 2628
+ + IS K +++S +P TFLT ++ + G+ + L C P + W
Sbjct: 229 QQKQPISVKVISAKSSRERP--PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA 286
Query: 2629 R-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
+ +G+L N+ Y+ TL++++ +DS Y C +N GAI + +++V
Sbjct: 287 KEDGMLPKNRTVYKNFEK----TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV---- 338
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFY 2744
+A+P T +++ E+ ++ CR G P P+I+W + I P D +
Sbjct: 339 KAAPYWITAPQNL--VLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRK--- 392
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
DG + N S Y C A N FVN V AE RI
Sbjct: 393 -IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVN------------VLAEPPRIL 438
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
+ N L YQV L G P +EW + G + ++ + V
Sbjct: 439 TPA---------NTL--YQVIANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLH 486
Query: 2864 EQGLYTLALSDVTETESGLYTCRA 2887
E G TL + + +G YTC A
Sbjct: 487 ENG--TLEIPVAQKDSTGTYTCVA 508
Score = 48.0 bits (109), Expect = 6e-04
Identities = 79/310 (25%), Positives = 124/310 (40%), Gaps = 44/310 (14%)
Query: 2604 TAVEGSRVKLTCSV-ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVLNAVPSDS 2661
T G + L C I P + W N +L +++ GL L N +P D+
Sbjct: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSF---QRLPQSERVSQGLNGDLYFSNVLPEDT 212
Query: 2662 AE-YSCTVE-NENGAISTSA--NLKVYPSFEASPIPPTFTR---SIRDTFHLAENELVLE 2714
E Y C N I ++KV + + PPTF + + L N L LE
Sbjct: 213 REDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLE 272
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGR-YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C G P P I W K+D +P + Y+ F L I + + DSG Y C A+N++
Sbjct: 273 CIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-----LQIIHVSEADSGNYQCIAKNAL 327
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
I H ++ + +P +TA Q+L VL+ GT+ +
Sbjct: 328 --GAIHHTISV---RVKAAPYWITAP------QNL---------VLSP---GEDGTLICR 364
Query: 2834 VEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
P R+ WL G + + ++ T+ S+V E S +Y C A + +G
Sbjct: 365 ANGNPKP-RISWLTNGVPIEIAPDDPSRKIDGD--TIIFSNVQERSSAVYQCNASNEYGY 421
Query: 2894 VDMNAAITVV 2903
+ NA + V+
Sbjct: 422 LLANAFVNVL 431
Score = 46.8 bits (106), Expect = 0.001
Identities = 67/267 (25%), Positives = 100/267 (37%), Gaps = 36/267 (13%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP T + +D + + + C+ G PPP SW ++G DK TL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 3226 EIAPTNLDDG------GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
I + +G GVY+ TARN GA + +VV E LEP+ L
Sbjct: 105 II--NIMSEGKAETYEGVYQCTARNERGAAVSN-NIVVRPSRSPLWTKE---KLEPI-TL 157
Query: 3280 HEGDELRISAVVEAYPSVG-----VTWYRDGV-RLRPSRRAIMTLDRDGQIELALAAVTT 3333
G L V+ P +G + W + RL S R L+ D L T
Sbjct: 158 QSGQSL----VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTR 213
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
D Y + + V+VI + E PP ++P+ S +
Sbjct: 214 EDYICYARFNHTQTIQQKQPISVKVISAKSSRER--PPTFLTPEGNAS----------NK 261
Query: 3394 EAREGDTVIIECEVVGDPKPDVYWLRD 3420
E G+ + +EC G P P +YW ++
Sbjct: 262 EELRGNVLSLECIAEGLPTPIIYWAKE 288
>AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 72.1 bits (169), Expect = 3e-11
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 11/167 (6%)
Query: 2612 KLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-YSCTVEN 2670
+L C+ +P + W ++G + R+ V + + V D A YSCT +N
Sbjct: 7 RLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQN 66
Query: 2671 ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKD 2730
G+IS +A L V + P+ + D + L+C+ G P P+ITWFK
Sbjct: 67 SAGSISANATLTVLET-------PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKG 119
Query: 2731 DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
D+ + R+ +L L + N ED+G YTC+ N++ T++
Sbjct: 120 DRPLSLTERH---HLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTER 163
Score = 69.7 bits (163), Expect = 2e-10
Identities = 53/190 (27%), Positives = 71/190 (37%), Gaps = 25/190 (13%)
Query: 3068 ANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEAT 3127
A L C+ G P P + W K+G A D I D+ IDD G YSC A
Sbjct: 6 ARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQ 65
Query: 3128 NTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRL 3187
N+ G S A L V+ P + L DR V V L
Sbjct: 66 NSAGSISANATLTVLE-----------------------TPSLVVPLEDRVVSVGETVAL 102
Query: 3188 TCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C+ G+PPP+++W+K + +R + D Q L + +D G Y N G
Sbjct: 103 QCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCEMSNTLG 160
Query: 3248 AVSCHCGLVV 3257
H L V
Sbjct: 161 TERAHSQLSV 170
Score = 68.9 bits (161), Expect = 3e-10
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 11/175 (6%)
Query: 3186 RLTCQVIGSPPPKVSWYKDG-EEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
RL C G P P+++W KDG + + R + I +DD GVY TA+N
Sbjct: 7 RLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQN 66
Query: 3245 NSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRD 3304
++G++S + L V P LE + G+ + + P +TW++
Sbjct: 67 SAGSISANATLTV------LETPSLVVPLEDRV-VSVGETVALQCKATGNPPPRITWFKG 119
Query: 3305 GVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
L + R +T D Q+ L + V DAG YTC SN +G ++ V+
Sbjct: 120 DRPLSLTERHHLT--PDNQL-LVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 171
Score = 51.2 bits (117), Expect = 6e-05
Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 9/114 (7%)
Query: 2832 LQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ G P ++ W ++G + R R+ V ++DV ++G+Y+C A ++
Sbjct: 8 LECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNS 67
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
G++ NA +TV++ P+++V P +D ++SVGE + + + G P P+
Sbjct: 68 AGSISANATLTVLE------TPSLVV--PLEDRVVSVGETVALQCKATGNPPPR 113
Score = 48.0 bits (109), Expect = 6e-04
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ GET L C G P P + W K + + N L ++++ +D GR
Sbjct: 94 VSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL---LVVQNVVAEDAGR 150
Query: 3122 YSCEATNTHGKASTYARLAVV 3142
Y+CE +NT G +++L+V+
Sbjct: 151 YTCEMSNTLGTERAHSQLSVL 171
Score = 44.4 bits (100), Expect = 0.007
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 24/135 (17%)
Query: 3286 RISAVVEAYPSVGVTWYRDGVRLRPS-RRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
R+ +P+ + W +DG P+ R M + D + + V DAGVY+CTA
Sbjct: 7 RLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQ 65
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
N G S + + V+ T P +V VP + + G+TV ++
Sbjct: 66 NSAGSISANATLTVLET--------PSLV----VPLEDRVVSV----------GETVALQ 103
Query: 3405 CEVVGDPKPDVYWLR 3419
C+ G+P P + W +
Sbjct: 104 CKATGNPPPRITWFK 118
Score = 43.6 bits (98), Expect = 0.013
Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 4/107 (3%)
Query: 2580 ISEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLK 2639
IS TL+ T P L DR G V L C + P +TW++ L L
Sbjct: 71 ISANATLTVLET--PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPL--SLT 126
Query: 2640 YRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
R L L V N V D+ Y+C + N G + L V P+
Sbjct: 127 ERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPA 173
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 72.1 bits (169), Expect = 3e-11
Identities = 75/313 (23%), Positives = 115/313 (36%), Gaps = 39/313 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P + W+ NG +E + + +G + ++
Sbjct: 355 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQE 412
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y C A+N +G A + V+ AE P T+
Sbjct: 413 RSSAVYQCNASNEYGYLLANAFVNVL-----------------AEPPRILTPANTLY--- 452
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+V A P L C GSP P + W+K + + + Y + TLEI D G
Sbjct: 453 -QVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIPVAQKDSTG 509
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y ARN G L + PE+ + G + V+ +
Sbjct: 510 TYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAV-------VQRGSMVSFECKVKHDHT 562
Query: 3297 VGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
+ +T W +D L R T+D+D L +A V+ D+G YTC A+ + S S
Sbjct: 563 LSLTVLWLKDNRELPSDER--FTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASA 617
Query: 3355 KVEVIGTDQTSEP 3367
+ V+ T P
Sbjct: 618 VLSVVAPTPTPAP 630
Score = 71.7 bits (168), Expect = 4e-11
Identities = 84/343 (24%), Positives = 137/343 (39%), Gaps = 45/343 (13%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T+S P + T + G L C + P ++W NGV ++ +
Sbjct: 340 TISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 399
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
+DG T+ N SA Y C NE G + +A + V PP +
Sbjct: 400 IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE------PPRILTPANTLY 452
Query: 2705 HLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+ N +L+C G PLP I WFK K ++ Y+ L I + +G
Sbjct: 453 QVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTG 509
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TYTC A N + +++V + A T I +Q P +
Sbjct: 510 TYTCVARNKLGM-----------AKNEVHLEIKDA--TWIVKQ------PEYA------V 544
Query: 2824 VARGGTIGLQVEIRGCPT---RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V RG + + +++ T V WL++ R E+ + R V++ L ++DV++ +S
Sbjct: 545 VQRGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKD--HLVVADVSDDDS 599
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G YTC A + +V +A ++VV P+ P V P D+
Sbjct: 600 GTYTCVANTTLDSVSASAVLSVVAPTPTPA-PVYDVPNPPFDL 641
Score = 68.1 bits (159), Expect = 5e-10
Identities = 92/345 (26%), Positives = 143/345 (41%), Gaps = 47/345 (13%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-----YS 2665
+ + C P+ +W RNG D + G TL ++N + AE Y
Sbjct: 71 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL-IINIMSEGKAETYEGVYQ 129
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
CT NE GA + S N+ V PS P +T+ + L + LVL CR G P P
Sbjct: 130 CTARNERGA-AVSNNIVVRPSRS-----PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPP 183
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAE-NSVWTDQITH 2780
I W + Q +P R D L N PED+ Y C A N T Q
Sbjct: 184 IIFWMDNSFQRLPQSERVSQGLNGD----LYFSNVLPEDTREDYICYARFNHTQTIQ--- 236
Query: 2781 FVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP 2840
++ +S V++A+ +R + + GN ++ + RG + L+ G P
Sbjct: 237 ------QKQPISVKVISAKSSRERPPTFLTPE---GNA-SNKEELRGNVLSLECIAEGLP 286
Query: 2841 TRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
T + W +E + +N V+ + TL + V+E +SG Y C A +A G + +
Sbjct: 287 TPIIYWAKEDGMLP---KNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTIS 342
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ V K A +++++S GED + R G PKP+
Sbjct: 343 VRV--------KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 379
Score = 55.6 bits (128), Expect = 3e-06
Identities = 85/369 (23%), Positives = 146/369 (39%), Gaps = 61/369 (16%)
Query: 3060 LKILAGETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + +G++ L C G P P + WM N + ++ R++ NG D + + D
Sbjct: 162 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG-DLYFS-NVLPEDT 219
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTM---RLR 3175
Y C A H T + ++ + + AK RER PP F
Sbjct: 220 REDYICYARFNH--TQTIQQKQPISVKVI---SAKSSRER--------PPTFLTPEGNAS 266
Query: 3176 DRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDG 3235
++ + L C G P P + W K E+ + K R Y++ + TL+I + D
Sbjct: 267 NKEELRGNVLSLECIAEGLPTPIIYWAK--EDGMLPKNRTVYKNFE-KTLQIIHVSEADS 323
Query: 3236 GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
G Y+ A+N GA+ H + +R AP + + L L G++ + P
Sbjct: 324 GNYQCIAKNALGAI--HHTI----SVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNP 376
Query: 3296 SVGVTWYRDGVRLR-----PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRA 3350
++W +GV + PSR+ +D D + + V R + VY C ASNE G
Sbjct: 377 KPRISWLTNGVPIEIAPDDPSRK----IDGD---TIIFSNVQERSSAVYQCNASNEYGYL 429
Query: 3351 STSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGD 3410
+ V V+ PP +++P + + +P +++C G
Sbjct: 430 LANAFVNVLAE--------PPRILTP--ANTLYQVIANRP----------ALLDCAFFGS 469
Query: 3411 PKPDVYWLR 3419
P P + W +
Sbjct: 470 PLPTIEWFK 478
Score = 50.0 bits (114), Expect = 1e-04
Identities = 80/324 (24%), Positives = 130/324 (40%), Gaps = 55/324 (16%)
Query: 2575 EARSVISEKRTLSRNSTRKPVFSTFLT------DRTAVEGSRVKLTCSVISSSDPTVTWY 2628
+ + IS K +++S +P TFLT ++ + G+ + L C P + W
Sbjct: 236 QQKQPISVKVISAKSSRERP--PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA 293
Query: 2629 R-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSF 2687
+ +G+L N+ Y+ TL++++ +DS Y C +N GAI + +++V
Sbjct: 294 KEDGMLPKNRTVYKNFEK----TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV---- 345
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFY 2744
+A+P T +++ E+ ++ CR G P P+I+W + I P D +
Sbjct: 346 KAAPYWITAPQNL--VLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRK--- 399
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIA 2804
DG + N S Y C A N FVN V AE RI
Sbjct: 400 -IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVN------------VLAEPPRIL 445
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
+ N L YQV L G P +EW + G + ++ + V
Sbjct: 446 TPA---------NTL--YQVIANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLH 493
Query: 2864 EQGLYTLALSDVTETESGLYTCRA 2887
E G TL + + +G YTC A
Sbjct: 494 ENG--TLEIPVAQKDSTGTYTCVA 515
Score = 48.0 bits (109), Expect = 6e-04
Identities = 79/310 (25%), Positives = 124/310 (40%), Gaps = 44/310 (14%)
Query: 2604 TAVEGSRVKLTCSV-ISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLI-TLEVLNAVPSDS 2661
T G + L C I P + W N +L +++ GL L N +P D+
Sbjct: 163 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSF---QRLPQSERVSQGLNGDLYFSNVLPEDT 219
Query: 2662 AE-YSCTVE-NENGAISTSA--NLKVYPSFEASPIPPTFTR---SIRDTFHLAENELVLE 2714
E Y C N I ++KV + + PPTF + + L N L LE
Sbjct: 220 REDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLE 279
Query: 2715 CRIRGQPLPKITWFKDDKQIPSDGR-YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
C G P P I W K+D +P + Y+ F L I + + DSG Y C A+N++
Sbjct: 280 CIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-----LQIIHVSEADSGNYQCIAKNAL 334
Query: 2774 WTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQ 2833
I H ++ + +P +TA Q+L VL+ GT+ +
Sbjct: 335 --GAIHHTISV---RVKAAPYWITAP------QNL---------VLSP---GEDGTLICR 371
Query: 2834 VEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGN 2893
P R+ WL G + + ++ T+ S+V E S +Y C A + +G
Sbjct: 372 ANGNPKP-RISWLTNGVPIEIAPDDPSRKIDGD--TIIFSNVQERSSAVYQCNASNEYGY 428
Query: 2894 VDMNAAITVV 2903
+ NA + V+
Sbjct: 429 LLANAFVNVL 438
Score = 46.8 bits (106), Expect = 0.001
Identities = 67/267 (25%), Positives = 100/267 (37%), Gaps = 36/267 (13%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP T + +D + + + C+ G PPP SW ++G DK TL
Sbjct: 52 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 111
Query: 3226 EIAPTNLDDG------GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
I + +G GVY+ TARN GA + +VV E LEP+ L
Sbjct: 112 II--NIMSEGKAETYEGVYQCTARNERGAAVSN-NIVVRPSRSPLWTKE---KLEPI-TL 164
Query: 3280 HEGDELRISAVVEAYPSVG-----VTWYRDGV-RLRPSRRAIMTLDRDGQIELALAAVTT 3333
G L V+ P +G + W + RL S R L+ D L T
Sbjct: 165 QSGQSL----VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTR 220
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSS 3393
D Y + + V+VI + E PP ++P+ S +
Sbjct: 221 EDYICYARFNHTQTIQQKQPISVKVISAKSSRER--PPTFLTPEGNAS----------NK 268
Query: 3394 EAREGDTVIIECEVVGDPKPDVYWLRD 3420
E G+ + +EC G P P +YW ++
Sbjct: 269 EELRGNVLSLECIAEGLPTPIIYWAKE 295
>AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein
protein.
Length = 1232
Score = 71.7 bits (168), Expect = 4e-11
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 10/207 (4%)
Query: 2569 RSKAFSEARSVISEKRTLSRNSTRK----PVFSTFLTDRTAVEGSRVKLTCSVISSSDPT 2624
+S A S +S++ E+ T + ++ + F T + EG R+ L ++ ++D
Sbjct: 819 KSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATD-- 876
Query: 2625 VTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVY 2684
W NGV L N +YR + TL + A D +C + + G + +L +
Sbjct: 877 AKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL- 935
Query: 2685 PSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFY 2744
S E S P ++ + +N L C I G+P P+I WFK++ I S +
Sbjct: 936 -SKELSDAPAFISQPRSQNINEGQNVL-FTCEISGEPSPEIEWFKNNLPI-SISSNVSIS 992
Query: 2745 LADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ V L I N + DSG YT KA+N
Sbjct: 993 RSRNVYSLEIRNASVSDSGKYTIKAKN 1019
Score = 68.1 bits (159), Expect = 5e-10
Identities = 56/238 (23%), Positives = 107/238 (44%), Gaps = 23/238 (9%)
Query: 2693 PPTFTRSIRDTFHLAENELV-LECRIRGQPL--PKITWFKDDKQIPSDGRYQAFYLADGV 2749
PP T+ ++ A E+ L C + L ++TW+KD K++ +G +Q Y ADG
Sbjct: 526 PPKITQFLKAE---ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGT 582
Query: 2750 CRLAIDNPTPEDSGTYTCKAENSVWTDQIT------HFVNFTGRESQVSPNVVTAEKT-- 2801
L I+N T D G + C+ T + F + + S++S + +KT
Sbjct: 583 YELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTE 642
Query: 2802 -RIARQSLE------SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE-WLREGRSVT 2853
+ R++ S +P L D V+ V+ G P W ++G+++T
Sbjct: 643 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 702
Query: 2854 EVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+ + ++ ++G + L + ++SGLYTC ++ G+V + +T+ D + +
Sbjct: 703 QGGK-YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 759
Score = 65.7 bits (153), Expect = 3e-09
Identities = 51/212 (24%), Positives = 88/212 (41%), Gaps = 21/212 (9%)
Query: 3066 ETANLTCSVKGKPVPG--VVWMKNGHEVEEEAGRMTSQFNGFDCC-LTIKDINIDDEGRY 3122
E A LTC V+ + V W K+G +++E G ++ L I ++ D+G +
Sbjct: 540 EIAKLTCVVESSVLRAKEVTWYKDGKKLKEN-GHFQFHYSADGTYELKINNLTESDQGEH 598
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRE-------------RSAEVEGDYP-- 3167
CE + G + T + +++ E +K+ R E + P
Sbjct: 599 VCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPIS 658
Query: 3168 --PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
P L+D V + + + G P P W KDG+ + + +D+ L
Sbjct: 659 SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFL 718
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
EI T+ D G+Y T +N++G+VS C L +
Sbjct: 719 EIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 750
Score = 62.5 bits (145), Expect = 3e-08
Identities = 80/354 (22%), Positives = 135/354 (38%), Gaps = 42/354 (11%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
KPV T L D T S K PT W ++G + KY+ G LE
Sbjct: 660 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 719
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANL--KVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+ SDS Y+CTV+N G++S+S L K EA + T I E
Sbjct: 720 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 779
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+ + +R + + K++ K +++ L + ++ I + + T E
Sbjct: 780 EISQKALRSEEI-KMSEAKSQEKLA---------LKEEASKVLISEEVKKSAAT---SLE 826
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
S+ ++IT + SQ S V T + + T + G +
Sbjct: 827 KSIVHEEIT-------KTSQASEEVRTHAEIKA--------------FSTQMSINEGQRL 865
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
L+ I G T +W+ G +T R V TL + + + G+ TC + +
Sbjct: 866 VLKANIAGA-TDAKWVLNGVELTN-SEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 923
Query: 2891 HGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
G V +T+ +L PA + +P I+ G+++ + GEP P+
Sbjct: 924 EGIVKCQYDLTL--SKELSDAPA-FISQPRSQ-NINEGQNVLFTCEISGEPSPE 973
Score = 61.7 bits (143), Expect = 5e-08
Identities = 75/366 (20%), Positives = 141/366 (38%), Gaps = 53/366 (14%)
Query: 3062 ILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGR 3121
+ + A G+P P +W K+G + + S+ G L I + D G
Sbjct: 672 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG-GFFLEIHKTDTSDSGL 730
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADA-KLKRERSAEVEGDYPPQFTMRLRDRRVQ 3180
Y+C N+ G S+ +L + + + + +A K+ ++++E+ PQ +
Sbjct: 731 YTCTVKNSAGSVSSSCKLTI---KAIKDTEAQKVSTQKTSEIT----PQ---------KK 774
Query: 3181 ATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
A ++ + + S K+S K E++ + +K + + A T+L+ V+E
Sbjct: 775 AVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKKSAATSLEKSIVHEE 833
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
+ + + I+A+ ++EG L + A + +
Sbjct: 834 ITKTSQASEEVR----THAEIKAFSTQ---------MSINEGQRLVLKANIAG--ATDAK 878
Query: 3301 WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
W +GV L S + Q L + + RD G+ TC + + G
Sbjct: 879 WVLNGVELTNSEEYRYGVSGSDQT-LTIKQASHRDEGILTCISKTKEGIVKCQ------- 930
Query: 3361 TDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
D T + S P FI +PRS EG V+ CE+ G+P P++ W ++
Sbjct: 931 YDLTLSKEL-----------SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKN 979
Query: 3421 FLKVRI 3426
L + I
Sbjct: 980 NLPISI 985
Score = 56.4 bits (130), Expect = 2e-06
Identities = 62/312 (19%), Positives = 122/312 (39%), Gaps = 24/312 (7%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDC 3107
D P F+ P I G+ TC + G+P P + W KN + + S+
Sbjct: 941 DAPAFIS-QPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV-Y 998
Query: 3108 CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYP 3167
L I++ ++ D G+Y+ +A N G+ S A L V+ + L+ ++G +
Sbjct: 999 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFS 1058
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
Q ++++ + +A++ S + + + E F +E+
Sbjct: 1059 SQ-SVQMSASKQEASFS--------SFSSSSASSMTEMKFASMSAQSMSSMQESF--VEM 1107
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRI 3287
+ ++ G+ +T +S + G+ +GI P L + EG L +
Sbjct: 1108 SSSSF--MGISNMTQLESSTSKMLKAGI---RGI-----PPKIEALPSDISIDEGKVLTV 1157
Query: 3288 SAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDR-DGQIELALAAVTTRDAGVYTCTASNE 3346
+ P+ VTW G ++ + ++ D L + V +D G+YT + NE
Sbjct: 1158 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 1217
Query: 3347 VGRASTSGKVEV 3358
G S + + +
Sbjct: 1218 FGSDSATVNIHI 1229
Score = 55.2 bits (127), Expect = 4e-06
Identities = 47/199 (23%), Positives = 78/199 (39%), Gaps = 22/199 (11%)
Query: 3059 QLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
Q+ I G+ L ++ G W+ NG E+ +G D LTIK + D
Sbjct: 856 QMSINEGQRLVLKANIAG--ATDAKWVLNGVELTNSE-EYRYGVSGSDQTLTIKQASHRD 912
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRR 3178
EG +C + G + D L +E S P F + R +
Sbjct: 913 EGILTCISKTKEGIVKC-------------QYDLTLSKELSDA------PAFISQPRSQN 953
Query: 3179 VQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVY 3238
+ V TC++ G P P++ W+K+ + + + ++LEI ++ D G Y
Sbjct: 954 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 1013
Query: 3239 EVTARNNSGAVSCHCGLVV 3257
+ A+N G S L+V
Sbjct: 1014 TIKAKNFRGQCSATASLMV 1032
Score = 55.2 bits (127), Expect = 4e-06
Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
TLS+ + P F + + EG V TC + P + W++N + +
Sbjct: 934 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 993
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDT 2703
+ +LE+ NA SDS +Y+ +N G S +A+L V P E P R+ DT
Sbjct: 994 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE-EPSREVVLRTSGDT 1051
Score = 54.4 bits (125), Expect = 7e-06
Identities = 32/128 (25%), Positives = 51/128 (39%), Gaps = 1/128 (0%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P + + GE+A +C G+PVP V W++ G +V + R + I +
Sbjct: 376 PRSMTVYEGESARFSCDTDGEPVPTVTWLRKG-QVLSTSARHQVTTTKYKSTFEISSVQA 434
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DEG YS N+ GK L + R +A R +S E P R
Sbjct: 435 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRV 494
Query: 3177 RRVQATYP 3184
+ + ++P
Sbjct: 495 KSPEPSHP 502
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/96 (30%), Positives = 40/96 (41%)
Query: 3165 DYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT 3224
D+ P+ T+R+R RV R V P +V WY +G E+ + + T
Sbjct: 180 DHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 239
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKG 3260
LEI + DD G Y N G S + L V G
Sbjct: 240 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGG 275
Score = 52.8 bits (121), Expect = 2e-05
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query: 2568 HRSKAFSEARSVISEKRTLSRNSTRKPVFSTF----LT---DRTAVEGSRVKLTCSVISS 2620
+ A +E +S E+++L ST + + +T LT T EG + +C
Sbjct: 337 YEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGE 396
Query: 2621 SDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENG 2673
PTVTW R G +L +++ T E+ + SD YS VEN G
Sbjct: 397 PVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 449
Score = 50.8 bits (116), Expect = 8e-05
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEV-EE 3093
S TS + G+ G P+ ++ LP + I G+ + C+ G+P P V W G ++ +
Sbjct: 1123 SSTSKMLKAGIRGIPPK-IEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 1181
Query: 3094 EAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
E GR + L I D+ D G Y+ N G S + +
Sbjct: 1182 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 1229
Score = 48.0 bits (109), Expect = 6e-04
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 3061 KILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEG 3120
++ G+ +V+ KP V W NG E++E + + +G L I D + DD G
Sbjct: 193 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGV-LTLEILDCHTDDSG 251
Query: 3121 RYSCEATNTHGKASTYARLAV 3141
Y TN G+AS YA L V
Sbjct: 252 TYRAVCTNYKGEASDYATLDV 272
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G R V++ P+ V WY +GV L+ S + T + G + L + T D+G Y
Sbjct: 197 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRA 255
Query: 3342 TASNEVGRASTSGKVEVIGTDQTS 3365
+N G AS ++V G D T+
Sbjct: 256 VCTNYKGEASDYATLDVTGGDYTT 279
Score = 45.2 bits (102), Expect = 0.004
Identities = 25/76 (32%), Positives = 31/76 (40%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G + +V S V WY NGV L K G++TLE+L+ DS Y
Sbjct: 197 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 256
Query: 2668 VENENGAISTSANLKV 2683
N G S A L V
Sbjct: 257 CTNYKGEASDYATLDV 272
Score = 44.8 bits (101), Expect = 0.006
Identities = 38/174 (21%), Positives = 72/174 (41%), Gaps = 8/174 (4%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
L + G+ K W +G E+ + TL I + D G+ ++
Sbjct: 867 LKANIAGATDAK--WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 924
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G V C L + K + AP F ++EG + + + PS + W+++ +
Sbjct: 925 GIVKCQYDLTLSKELSD--APAFISQPRS-QNINEGQNVLFTCEISGEPSPEIEWFKNNL 981
Query: 3307 RLRPSRRAIMTLDRDG-QIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+ S ++ R+ +E+ A+V+ D+G YT A N G+ S + + V+
Sbjct: 982 PISISSNVSISRSRNVYSLEIRNASVS--DSGKYTIKAKNFRGQCSATASLMVL 1033
Score = 44.0 bits (99), Expect = 0.010
Identities = 31/140 (22%), Positives = 54/140 (38%), Gaps = 18/140 (12%)
Query: 3299 VTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTS----- 3353
VTWY+DG +L+ + DG EL + +T D G + C S E G + T+
Sbjct: 558 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMG 617
Query: 3354 -------GKVEVIGTDQTSEPRIPPVVISPDV------PYSKEPMFIRKPRSSEAREGDT 3400
KV I + S+ + ++ P S +P+ + + +
Sbjct: 618 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSV 677
Query: 3401 VIIECEVVGDPKPDVYWLRD 3420
+ G+P+P W +D
Sbjct: 678 AKFAVKATGEPRPTAIWTKD 697
Score = 42.3 bits (95), Expect = 0.030
Identities = 28/136 (20%), Positives = 50/136 (36%), Gaps = 1/136 (0%)
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA-EVEGDYPPQFTMRLRDRRVQATY 3183
+ T T S+Y A ++ + L+ + + +++ + + R V
Sbjct: 326 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGE 385
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
R +C G P P V+W + G+ + R + T EI+ D G Y V
Sbjct: 386 SARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 445
Query: 3244 NNSGAVSCHCGLVVDK 3259
N+ G L + K
Sbjct: 446 NSEGKQEAEFTLTIQK 461
Score = 41.9 bits (94), Expect = 0.039
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 3/120 (2%)
Query: 3279 LHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
++EG+ R S + P VTW R G L S R +T + + +++V D G
Sbjct: 381 VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQASDEGN 439
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEP-RIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
Y+ N G+ + + T + PP V SP+ P K P ++ P+ ++ E
Sbjct: 440 YSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPE-PRVKSPEAVKSPKRVKSPE 498
Score = 39.9 bits (89), Expect = 0.16
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 2612 KLTCSVISS--SDPTVTWYRNGVLLDNKLKYRKKL-VDGLITLEVLNAVPSDSAEYSCTV 2668
KLTC V SS VTWY++G L ++ DG L++ N SD E+ C +
Sbjct: 543 KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEI 602
Query: 2669 ENENGAISTS 2678
E G T+
Sbjct: 603 SGEGGTSKTN 612
Score = 37.1 bits (82), Expect = 1.1
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL--VDGLITL 2651
P +D + EG + + C+ P VTW G + ++ + R + D L TL
Sbjct: 1138 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 1197
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+++ D Y+ ++ NE G+ S + N+ +
Sbjct: 1198 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 1229
Score = 35.9 bits (79), Expect = 2.6
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPS--DGRYQAFYLADGVCRLAIDNPTPEDSGTYTCK 2768
L + C G+P P++TW ++I S GR+ D + L I + +D G YT
Sbjct: 1155 LTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFH-IENTDDLTTLIIMDVQKQDGGLYTLS 1213
Query: 2769 AENSVWTDQIT 2779
N +D T
Sbjct: 1214 LGNEFGSDSAT 1224
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 3387 IRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
+ KPRS EG++ C+ G+P P V WLR
Sbjct: 373 LTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 405
Score = 35.5 bits (78), Expect = 3.4
Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F + + G + EI G P+ +EW + ++ + N + + +Y
Sbjct: 940 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS-ISSNVSISRSRNVY 998
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
+L + + + ++SG YT +A + G A++ V+
Sbjct: 999 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 1033
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 71.7 bits (168), Expect = 4e-11
Identities = 83/343 (24%), Positives = 138/343 (40%), Gaps = 45/343 (13%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T+S P + T + G L C + P ++W NGV ++ +
Sbjct: 347 TISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 406
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
+DG T+ N SA Y C NE G + +A + V PP +
Sbjct: 407 IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE------PPRILTPANTLY 459
Query: 2705 HLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+ N +L+C G PLP I WFK K ++ Y+ L I + +G
Sbjct: 460 QVIANRPALLDCAFFGSPLPTIQWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTG 516
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TYTC A N + +++V ++ + T I +Q P +
Sbjct: 517 TYTCVARNKLGM-----------AKNEV--HLEIKDPTWIVKQ------PEYA------V 551
Query: 2824 VARGGTIGLQVEIRGCPT---RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V RG + + +++ T V WL++ R E+ + R V++ L ++DV++ +S
Sbjct: 552 VQRGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKD--HLVVADVSDDDS 606
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G YTC A + +V +A ++VV P+ P V P D+
Sbjct: 607 GTYTCVANTTLDSVSASAVLSVVAPTPTPA-PVYDVPNPPLDL 648
Score = 71.3 bits (167), Expect = 6e-11
Identities = 75/313 (23%), Positives = 115/313 (36%), Gaps = 39/313 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P + W+ NG +E + + +G + ++
Sbjct: 362 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQE 419
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y C A+N +G A + V+ AE P T+
Sbjct: 420 RSSAVYQCNASNEYGYLLANAFVNVL-----------------AEPPRILTPANTLY--- 459
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+V A P L C GSP P + W+K + + + Y + TLEI D G
Sbjct: 460 -QVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHE--DIYVLHENGTLEIPVAQKDSTG 516
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y ARN G L + PE+ + G + V+ +
Sbjct: 517 TYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV-------VQRGSMVSFECKVKHDHT 569
Query: 3297 VGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
+ +T W +D L R T+D+D L +A V+ D+G YTC A+ + S S
Sbjct: 570 LSLTVLWLKDNRELPSDER--FTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASA 624
Query: 3355 KVEVIGTDQTSEP 3367
+ V+ T P
Sbjct: 625 VLSVVAPTPTPAP 637
Score = 66.1 bits (154), Expect = 2e-09
Identities = 93/352 (26%), Positives = 141/352 (40%), Gaps = 42/352 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-----YS 2665
+ + C P+ +W RNG D + G TL ++N + AE Y
Sbjct: 59 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL-IINIMSEGKAETYEGVYQ 117
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
CT NE GA + S N+ V PS P +T+ + L + LVL CR G P P
Sbjct: 118 CTARNERGA-AVSNNIVVRPSRS-----PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPP 171
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAE-NSVWTDQITH 2780
I W + Q +P R D L N PED+ Y C A N T Q
Sbjct: 172 IIFWMDNSFQRLPQSERVSQGLNGD----LYFSNVLPEDTREDYICYARFNHTQTIQQKQ 227
Query: 2781 FVNFTGRESQVSPNVVTAEKTRI---ARQSLESRRPHF----GNVLTDYQVARGGTIGLQ 2833
++ + + A + +S R P F GN ++ + RG + L+
Sbjct: 228 PISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNA-SNKEELRGNVLSLE 286
Query: 2834 VEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G PT + W +E + +N V+ + TL + V+E +SG Y C A +A G
Sbjct: 287 CIAEGLPTPIIYWAKEDGMLP---KNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKNALG 342
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ ++ V K A +++++S GED + R G PKP+
Sbjct: 343 AIHHTISVRV--------KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 386
Score = 54.8 bits (126), Expect = 5e-06
Identities = 84/375 (22%), Positives = 147/375 (39%), Gaps = 54/375 (14%)
Query: 3060 LKILAGETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + +G++ L C G P P + WM N + ++ R++ NG D + + D
Sbjct: 150 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG-DLYFS-NVLPEDT 207
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS------AEVEGDYPPQFTM 3172
Y C A H + + V +V E + + S A+ + PP F
Sbjct: 208 REDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLT 267
Query: 3173 ---RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
++ + L C G P P + W K E+ + K R Y++ + TL+I
Sbjct: 268 PEGNASNKEELRGNVLSLECIAEGLPTPIIYWAK--EDGMLPKNRTVYKNFE-KTLQIIH 324
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ D G Y+ A+N GA+ H + +R AP + + L L G++ +
Sbjct: 325 VSEADSGNYQCIAKNALGAI--HHTI----SVRVKAAPYWITAPQNLV-LSPGEDGTLIC 377
Query: 3290 VVEAYPSVGVTWYRDGVRLR-----PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
P ++W +GV + PSR+ +D D + + V R + VY C AS
Sbjct: 378 RANGNPKPRISWLTNGVPIEIAPDDPSRK----IDGD---TIIFSNVQERSSAVYQCNAS 430
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
NE G + V V+ PP +++P + + +P +++
Sbjct: 431 NEYGYLLANAFVNVLAE--------PPRILTP--ANTLYQVIANRP----------ALLD 470
Query: 3405 CEVVGDPKPDVYWLR 3419
C G P P + W +
Sbjct: 471 CAFFGSPLPTIQWFK 485
Score = 48.8 bits (111), Expect = 3e-04
Identities = 78/333 (23%), Positives = 130/333 (39%), Gaps = 50/333 (15%)
Query: 2592 RKPVFST---FLTDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDG 2647
R P F T +++ + G+ + L C P + W + +G+L N+ Y+
Sbjct: 261 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-- 318
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
TL++++ +DS Y C +N GAI + +++V +A+P T +++
Sbjct: 319 --TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV----KAAPYWITAPQNL--VLSPG 370
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
E+ ++ CR G P P+I+W + I P D + DG + N S
Sbjct: 371 EDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRK----IDG-DTIIFSNVQERSSAV 424
Query: 2765 YTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Y C A N FVN V AE RI + N L YQV
Sbjct: 425 YQCNASNEYGYLLANAFVN------------VLAEPPRILTPA---------NTL--YQV 461
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
L G P ++W + G + ++ + V E G TL + + +G Y
Sbjct: 462 IANRPALLDCAFFGSPLPTIQWFK-GAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTY 518
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIV 2916
TC A + G + + P+ + +P V
Sbjct: 519 TCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV 551
Score = 44.8 bits (101), Expect = 0.006
Identities = 67/274 (24%), Positives = 105/274 (38%), Gaps = 31/274 (11%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP T + +D + + + C+ G PPP SW ++G DK TL
Sbjct: 40 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 99
Query: 3226 EIAPTNLDDG------GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
I + +G GVY+ TARN GA + +VV E LEP+ L
Sbjct: 100 II--NIMSEGKAETYEGVYQCTARNERGAAVSN-NIVVRPSRSPLWTKE---KLEPI-TL 152
Query: 3280 HEGDELRISAVVEAYPSVG-----VTWYRDGV-RLRPSRRAIMTLDRDGQIELALAAVTT 3333
G L V+ P +G + W + RL S R L+ D L T
Sbjct: 153 QSGQSL----VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTR 208
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISP--DVPYSKE--PMFIRK 3389
D Y + + V+VI D+ ++ + + S+E P F+
Sbjct: 209 EDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTP 268
Query: 3390 PRSSEARE---GDTVIIECEVVGDPKPDVYWLRD 3420
++ +E G+ + +EC G P P +YW ++
Sbjct: 269 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE 302
Score = 35.9 bits (79), Expect = 2.6
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 15/159 (9%)
Query: 2987 WLIGAEGGARWVELGITPLNSFDAFNLKQGEEYH-FRVTPRNRYGWGESSQTSSSIGVGL 3045
W GA+G A ++ + N + Q + + RN+ G ++ V L
Sbjct: 483 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE-------VHL 535
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPG--VVWMKNGHEVEEEAGRMTSQFN 3103
P ++ P + G + C VK V+W+K+ E+ + R T +
Sbjct: 536 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE-RFTVDKD 594
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L + D++ DD G Y+C A T S A L+VV
Sbjct: 595 H----LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV 629
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 71.3 bits (167), Expect = 6e-11
Identities = 78/305 (25%), Positives = 120/305 (39%), Gaps = 56/305 (18%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L G+ L C G PVP + W K + A TS L I +I ++DEG Y
Sbjct: 254 LMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS-----GAVLKIFNIQLEDEGIY 308
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
CEA N G K + A + P++ + D V
Sbjct: 309 ECEAENIRG-----------------------KDKHQARIYVQAFPEWVEHINDTEVDIG 345
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
+ C G P P + W K+G Y K + D F ++ G+Y+ A
Sbjct: 346 SDLYWPCVATGKPIPTIRWLKNG--YAYHKGELRLYDVTF----------ENAGMYQCIA 393
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK---LHEGDELRISAVVEAYPSVGV 3299
N GA+ + L + +AP F + P+ K +G + I +A P
Sbjct: 394 ENTYGAIYANAELKI-----LALAPTF--EMNPMKKKILAAKGGRVIIECKPKAAPKPKF 446
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+W + L S R ++ DG +E+ +T D G+YTC A N G+A+++G + +
Sbjct: 447 SWSKGTEWLVNSSRILIW--EDGSLEIN--NITRNDGGIYTCFAENNRGKANSTGTLVI- 501
Query: 3360 GTDQT 3364
TD T
Sbjct: 502 -TDPT 505
Score = 69.3 bits (162), Expect = 2e-10
Identities = 78/316 (24%), Positives = 128/316 (40%), Gaps = 49/316 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
PE+V+ + ++ G C GKP+P + W+KNG+ + L
Sbjct: 331 PEWVEHI-NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE-------------L 376
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ D+ ++ G Y C A NT+G A L ++ +E + K+ +A+ G
Sbjct: 377 RLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAK--GGR--- 431
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
V + C+ +P PK SW K E +V R ++D +LEI
Sbjct: 432 ---------------VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDG---SLEINN 473
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+DGG+Y A NN G + LV+ R +AP + + E ++ +A
Sbjct: 474 ITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP-----INADITVGENATMQCAA 528
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAI-----MTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + W +G + ++ I LD +G EL + + AG YTCTA
Sbjct: 529 SFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG--ELLIRNAQLKHAGRYTCTAQ 586
Query: 3345 NEVGRASTSGKVEVIG 3360
V +S S + V G
Sbjct: 587 TIVDNSSASADLVVRG 602
Score = 61.7 bits (143), Expect = 5e-08
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 26/182 (14%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + + D GS + C PT+ W +NG K +L D +T E
Sbjct: 331 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH---KGELRLYD--VTFE- 384
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAENE 2710
++ Y C EN GAI +A LK+ P+FE +P+ +
Sbjct: 385 ------NAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAA-------KGGR 431
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+++EC+ + P PK +W K + + + R + DG L I+N T D G YTC AE
Sbjct: 432 VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW--EDG--SLEINNITRNDGGIYTCFAE 487
Query: 2771 NS 2772
N+
Sbjct: 488 NN 489
Score = 56.8 bits (131), Expect = 1e-06
Identities = 73/298 (24%), Positives = 111/298 (37%), Gaps = 52/298 (17%)
Query: 2651 LEVLNAVPSDSAEYSCTVENEN---GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + N SD YSC V + + S L P P P +D + L
Sbjct: 196 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALM 255
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ LEC G P+P I W K + +PS ++ L I N ED G Y C
Sbjct: 256 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAE-----ISTSGAVLKIFNIQLEDEGIYEC 310
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
+AE N G++ + RI Q+ P + + D +V G
Sbjct: 311 EAE------------NIRGKDKH---------QARIYVQAF----PEWVEHINDTEVDIG 345
Query: 2828 GTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCR 2886
+ G P + WL+ G + Y L L DVT +G+Y C
Sbjct: 346 SDLYWPCVATGKPIPTIRWLKNGYA----YHKGE---------LRLYDVTFENAGMYQCI 392
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
A + +G + NA + ++ + P + +K IL + G + I + + PKPK
Sbjct: 393 AENTYGAIYANAELKILALA-----PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPK 445
Score = 50.8 bits (116), Expect = 8e-05
Identities = 65/307 (21%), Positives = 123/307 (40%), Gaps = 53/307 (17%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D A+ G V L C + + P + W + +L+ + G + L++ N D
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRK---VLEPMPSTAEISTSGAV-LKIFNIQLEDE 305
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y C EN G A + V +F P + I DT ++L C G+P
Sbjct: 306 GIYECEAENIRGKDKHQARIYV-QAF------PEWVEHINDTEVDIGSDLYWPCVATGKP 358
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+P I W K+ A++ + L + + T E++G Y C AEN T+
Sbjct: 359 IPTIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAEN-------TYG 398
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP- 2840
+ E ++ T E + ++ L A+GG + ++ + + P
Sbjct: 399 AIYANAELKILALAPTFEMNPMKKKIL---------------AAKGGRVIIECKPKAAPK 443
Query: 2841 TRVEWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W + + ++R+ + E G +L ++++T + G+YTC A + G +
Sbjct: 444 PKFSW---SKGTEWLVNSSRILIWEDG--SLEINNITRNDGGIYTCFAENNRGKANSTGT 498
Query: 2900 ITVVQPS 2906
+ + P+
Sbjct: 499 LVITDPT 505
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 71.3 bits (167), Expect = 6e-11
Identities = 78/305 (25%), Positives = 120/305 (39%), Gaps = 56/305 (18%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L G+ L C G PVP + W K + A TS L I +I ++DEG Y
Sbjct: 243 LMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS-----GAVLKIFNIQLEDEGIY 297
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
CEA N G K + A + P++ + D V
Sbjct: 298 ECEAENIRG-----------------------KDKHQARIYVQAFPEWVEHINDTEVDIG 334
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
+ C G P P + W K+G Y K + D F ++ G+Y+ A
Sbjct: 335 SDLYWPCVATGKPIPTIRWLKNG--YAYHKGELRLYDVTF----------ENAGMYQCIA 382
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK---LHEGDELRISAVVEAYPSVGV 3299
N GA+ + L + +AP F + P+ K +G + I +A P
Sbjct: 383 ENTYGAIYANAELKI-----LALAPTF--EMNPMKKKILAAKGGRVIIECKPKAAPKPKF 435
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+W + L S R ++ DG +E+ +T D G+YTC A N G+A+++G + +
Sbjct: 436 SWSKGTEWLVNSSRILIW--EDGSLEIN--NITRNDGGIYTCFAENNRGKANSTGTLVI- 490
Query: 3360 GTDQT 3364
TD T
Sbjct: 491 -TDPT 494
Score = 69.3 bits (162), Expect = 2e-10
Identities = 78/316 (24%), Positives = 128/316 (40%), Gaps = 49/316 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
PE+V+ + ++ G C GKP+P + W+KNG+ + L
Sbjct: 320 PEWVEHI-NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE-------------L 365
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ D+ ++ G Y C A NT+G A L ++ +E + K+ +A+ G
Sbjct: 366 RLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAK--GGR--- 420
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
V + C+ +P PK SW K E +V R ++D +LEI
Sbjct: 421 ---------------VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDG---SLEINN 462
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+DGG+Y A NN G + LV+ R +AP + + E ++ +A
Sbjct: 463 ITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP-----INADITVGENATMQCAA 517
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAI-----MTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + W +G + ++ I LD +G EL + + AG YTCTA
Sbjct: 518 SFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG--ELLIRNAQLKHAGRYTCTAQ 575
Query: 3345 NEVGRASTSGKVEVIG 3360
V +S S + V G
Sbjct: 576 TIVDNSSASADLVVRG 591
Score = 61.7 bits (143), Expect = 5e-08
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 26/182 (14%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + + D GS + C PT+ W +NG K +L D +T E
Sbjct: 320 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH---KGELRLYD--VTFE- 373
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAENE 2710
++ Y C EN GAI +A LK+ P+FE +P+ +
Sbjct: 374 ------NAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAA-------KGGR 420
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+++EC+ + P PK +W K + + + R + DG L I+N T D G YTC AE
Sbjct: 421 VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW--EDG--SLEINNITRNDGGIYTCFAE 476
Query: 2771 NS 2772
N+
Sbjct: 477 NN 478
Score = 56.8 bits (131), Expect = 1e-06
Identities = 73/298 (24%), Positives = 111/298 (37%), Gaps = 52/298 (17%)
Query: 2651 LEVLNAVPSDSAEYSCTVENEN---GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + N SD YSC V + + S L P P P +D + L
Sbjct: 185 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALM 244
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ LEC G P+P I W K + +PS ++ L I N ED G Y C
Sbjct: 245 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAE-----ISTSGAVLKIFNIQLEDEGIYEC 299
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
+AE N G++ + RI Q+ P + + D +V G
Sbjct: 300 EAE------------NIRGKDKH---------QARIYVQAF----PEWVEHINDTEVDIG 334
Query: 2828 GTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCR 2886
+ G P + WL+ G + Y L L DVT +G+Y C
Sbjct: 335 SDLYWPCVATGKPIPTIRWLKNGYA----YHKGE---------LRLYDVTFENAGMYQCI 381
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
A + +G + NA + ++ + P + +K IL + G + I + + PKPK
Sbjct: 382 AENTYGAIYANAELKILALA-----PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPK 434
Score = 50.8 bits (116), Expect = 8e-05
Identities = 65/307 (21%), Positives = 123/307 (40%), Gaps = 53/307 (17%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D A+ G V L C + + P + W + +L+ + G + L++ N D
Sbjct: 239 DVYALMGQNVTLECFALGNPVPDIRWRK---VLEPMPSTAEISTSGAV-LKIFNIQLEDE 294
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y C EN G A + V +F P + I DT ++L C G+P
Sbjct: 295 GIYECEAENIRGKDKHQARIYV-QAF------PEWVEHINDTEVDIGSDLYWPCVATGKP 347
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+P I W K+ A++ + L + + T E++G Y C AEN T+
Sbjct: 348 IPTIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAEN-------TYG 387
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP- 2840
+ E ++ T E + ++ L A+GG + ++ + + P
Sbjct: 388 AIYANAELKILALAPTFEMNPMKKKIL---------------AAKGGRVIIECKPKAAPK 432
Query: 2841 TRVEWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W + + ++R+ + E G +L ++++T + G+YTC A + G +
Sbjct: 433 PKFSW---SKGTEWLVNSSRILIWEDG--SLEINNITRNDGGIYTCFAENNRGKANSTGT 487
Query: 2900 ITVVQPS 2906
+ + P+
Sbjct: 488 LVITDPT 494
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 71.3 bits (167), Expect = 6e-11
Identities = 78/305 (25%), Positives = 120/305 (39%), Gaps = 56/305 (18%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L G+ L C G PVP + W K + A TS L I +I ++DEG Y
Sbjct: 254 LMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS-----GAVLKIFNIQLEDEGIY 308
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
CEA N G K + A + P++ + D V
Sbjct: 309 ECEAENIRG-----------------------KDKHQARIYVQAFPEWVEHINDTEVDIG 345
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
+ C G P P + W K+G Y K + D F ++ G+Y+ A
Sbjct: 346 SDLYWPCVATGKPIPTIRWLKNG--YAYHKGELRLYDVTF----------ENAGMYQCIA 393
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK---LHEGDELRISAVVEAYPSVGV 3299
N GA+ + L + +AP F + P+ K +G + I +A P
Sbjct: 394 ENTYGAIYANAELKI-----LALAPTF--EMNPMKKKILAAKGGRVIIECKPKAAPKPKF 446
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+W + L S R ++ DG +E+ +T D G+YTC A N G+A+++G + +
Sbjct: 447 SWSKGTEWLVNSSRILIW--EDGSLEIN--NITRNDGGIYTCFAENNRGKANSTGTLVI- 501
Query: 3360 GTDQT 3364
TD T
Sbjct: 502 -TDPT 505
Score = 69.3 bits (162), Expect = 2e-10
Identities = 78/316 (24%), Positives = 128/316 (40%), Gaps = 49/316 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
PE+V+ + ++ G C GKP+P + W+KNG+ + L
Sbjct: 331 PEWVEHI-NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE-------------L 376
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ D+ ++ G Y C A NT+G A L ++ +E + K+ +A+ G
Sbjct: 377 RLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAK--GGR--- 431
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
V + C+ +P PK SW K E +V R ++D +LEI
Sbjct: 432 ---------------VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDG---SLEINN 473
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+DGG+Y A NN G + LV+ R +AP + + E ++ +A
Sbjct: 474 ITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP-----INADITVGENATMQCAA 528
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAI-----MTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + W +G + ++ I LD +G EL + + AG YTCTA
Sbjct: 529 SFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG--ELLIRNAQLKHAGRYTCTAQ 586
Query: 3345 NEVGRASTSGKVEVIG 3360
V +S S + V G
Sbjct: 587 TIVDNSSASADLVVRG 602
Score = 61.7 bits (143), Expect = 5e-08
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 26/182 (14%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + + D GS + C PT+ W +NG K +L D +T E
Sbjct: 331 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH---KGELRLYD--VTFE- 384
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAENE 2710
++ Y C EN GAI +A LK+ P+FE +P+ +
Sbjct: 385 ------NAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAA-------KGGR 431
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+++EC+ + P PK +W K + + + R + DG L I+N T D G YTC AE
Sbjct: 432 VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW--EDG--SLEINNITRNDGGIYTCFAE 487
Query: 2771 NS 2772
N+
Sbjct: 488 NN 489
Score = 56.8 bits (131), Expect = 1e-06
Identities = 73/298 (24%), Positives = 111/298 (37%), Gaps = 52/298 (17%)
Query: 2651 LEVLNAVPSDSAEYSCTVENEN---GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + N SD YSC V + + S L P P P +D + L
Sbjct: 196 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALM 255
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ LEC G P+P I W K + +PS ++ L I N ED G Y C
Sbjct: 256 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAE-----ISTSGAVLKIFNIQLEDEGIYEC 310
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
+AE N G++ + RI Q+ P + + D +V G
Sbjct: 311 EAE------------NIRGKDKH---------QARIYVQAF----PEWVEHINDTEVDIG 345
Query: 2828 GTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCR 2886
+ G P + WL+ G + Y L L DVT +G+Y C
Sbjct: 346 SDLYWPCVATGKPIPTIRWLKNGYA----YHKGE---------LRLYDVTFENAGMYQCI 392
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
A + +G + NA + ++ + P + +K IL + G + I + + PKPK
Sbjct: 393 AENTYGAIYANAELKILALA-----PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPK 445
Score = 50.8 bits (116), Expect = 8e-05
Identities = 65/307 (21%), Positives = 123/307 (40%), Gaps = 53/307 (17%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D A+ G V L C + + P + W + +L+ + G + L++ N D
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRK---VLEPMPSTAEISTSGAV-LKIFNIQLEDE 305
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y C EN G A + V +F P + I DT ++L C G+P
Sbjct: 306 GIYECEAENIRGKDKHQARIYV-QAF------PEWVEHINDTEVDIGSDLYWPCVATGKP 358
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+P I W K+ A++ + L + + T E++G Y C AEN T+
Sbjct: 359 IPTIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAEN-------TYG 398
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP- 2840
+ E ++ T E + ++ L A+GG + ++ + + P
Sbjct: 399 AIYANAELKILALAPTFEMNPMKKKIL---------------AAKGGRVIIECKPKAAPK 443
Query: 2841 TRVEWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W + + ++R+ + E G +L ++++T + G+YTC A + G +
Sbjct: 444 PKFSW---SKGTEWLVNSSRILIWEDG--SLEINNITRNDGGIYTCFAENNRGKANSTGT 498
Query: 2900 ITVVQPS 2906
+ + P+
Sbjct: 499 LVITDPT 505
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 71.3 bits (167), Expect = 6e-11
Identities = 78/305 (25%), Positives = 120/305 (39%), Gaps = 56/305 (18%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L G+ L C G PVP + W K + A TS L I +I ++DEG Y
Sbjct: 254 LMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS-----GAVLKIFNIQLEDEGIY 308
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
CEA N G K + A + P++ + D V
Sbjct: 309 ECEAENIRG-----------------------KDKHQARIYVQAFPEWVEHINDTEVDIG 345
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
+ C G P P + W K+G Y K + D F ++ G+Y+ A
Sbjct: 346 SDLYWPCVATGKPIPTIRWLKNG--YAYHKGELRLYDVTF----------ENAGMYQCIA 393
Query: 3243 RNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYK---LHEGDELRISAVVEAYPSVGV 3299
N GA+ + L + +AP F + P+ K +G + I +A P
Sbjct: 394 ENTYGAIYANAELKI-----LALAPTF--EMNPMKKKILAAKGGRVIIECKPKAAPKPKF 446
Query: 3300 TWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVI 3359
+W + L S R ++ DG +E+ +T D G+YTC A N G+A+++G + +
Sbjct: 447 SWSKGTEWLVNSSRILIW--EDGSLEIN--NITRNDGGIYTCFAENNRGKANSTGTLVI- 501
Query: 3360 GTDQT 3364
TD T
Sbjct: 502 -TDPT 505
Score = 69.7 bits (163), Expect = 2e-10
Identities = 78/319 (24%), Positives = 130/319 (40%), Gaps = 49/319 (15%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
PE+V+ + ++ G C GKP+P + W+KNG+ + L
Sbjct: 331 PEWVEHI-NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE-------------L 376
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQ 3169
+ D+ ++ G Y C A NT+G A L ++ +E + K+ +A+ G
Sbjct: 377 RLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAK--GGR--- 431
Query: 3170 FTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
V + C+ +P PK SW K E +V R ++D +LEI
Sbjct: 432 ---------------VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDG---SLEINN 473
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+DGG+Y A NN G + LV+ R +AP + + E ++ +A
Sbjct: 474 ITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP-----INADITVGENATMQCAA 528
Query: 3290 VVEAYPSVGVTWYRDGVRLRPSRRAI-----MTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + W +G + ++ I LD +G EL + + AG YTCTA
Sbjct: 529 SFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG--ELLIRNAQLKHAGRYTCTAQ 586
Query: 3345 NEVGRASTSGKVEVIGTDQ 3363
V +S S + V G ++
Sbjct: 587 TIVDNSSASADLVVRGKNR 605
Score = 61.7 bits (143), Expect = 5e-08
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 26/182 (14%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P + + D GS + C PT+ W +NG K +L D +T E
Sbjct: 331 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH---KGELRLYD--VTFE- 384
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVY---PSFEASPIPPTFTRSIRDTFHLAENE 2710
++ Y C EN GAI +A LK+ P+FE +P+ +
Sbjct: 385 ------NAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAA-------KGGR 431
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
+++EC+ + P PK +W K + + + R + DG L I+N T D G YTC AE
Sbjct: 432 VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW--EDG--SLEINNITRNDGGIYTCFAE 487
Query: 2771 NS 2772
N+
Sbjct: 488 NN 489
Score = 56.8 bits (131), Expect = 1e-06
Identities = 73/298 (24%), Positives = 111/298 (37%), Gaps = 52/298 (17%)
Query: 2651 LEVLNAVPSDSAEYSCTVENEN---GAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
L + N SD YSC V + + S L P P P +D + L
Sbjct: 196 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALM 255
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTC 2767
+ LEC G P+P I W K + +PS ++ L I N ED G Y C
Sbjct: 256 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAE-----ISTSGAVLKIFNIQLEDEGIYEC 310
Query: 2768 KAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARG 2827
+AE N G++ + RI Q+ P + + D +V G
Sbjct: 311 EAE------------NIRGKDKH---------QARIYVQAF----PEWVEHINDTEVDIG 345
Query: 2828 GTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCR 2886
+ G P + WL+ G + Y L L DVT +G+Y C
Sbjct: 346 SDLYWPCVATGKPIPTIRWLKNGYA----YHKGE---------LRLYDVTFENAGMYQCI 392
Query: 2887 AWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
A + +G + NA + ++ + P + +K IL + G + I + + PKPK
Sbjct: 393 AENTYGAIYANAELKILALA-----PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPK 445
Score = 50.8 bits (116), Expect = 8e-05
Identities = 65/307 (21%), Positives = 123/307 (40%), Gaps = 53/307 (17%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS 2661
D A+ G V L C + + P + W + +L+ + G + L++ N D
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRK---VLEPMPSTAEISTSGAV-LKIFNIQLEDE 305
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
Y C EN G A + V +F P + I DT ++L C G+P
Sbjct: 306 GIYECEAENIRGKDKHQARIYV-QAF------PEWVEHINDTEVDIGSDLYWPCVATGKP 358
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHF 2781
+P I W K+ A++ + L + + T E++G Y C AEN T+
Sbjct: 359 IPTIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAEN-------TYG 398
Query: 2782 VNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP- 2840
+ E ++ T E + ++ L A+GG + ++ + + P
Sbjct: 399 AIYANAELKILALAPTFEMNPMKKKIL---------------AAKGGRVIIECKPKAAPK 443
Query: 2841 TRVEWLREGRSVTEVYRNARVFV-EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
+ W + + ++R+ + E G +L ++++T + G+YTC A + G +
Sbjct: 444 PKFSW---SKGTEWLVNSSRILIWEDG--SLEINNITRNDGGIYTCFAENNRGKANSTGT 498
Query: 2900 ITVVQPS 2906
+ + P+
Sbjct: 499 LVITDPT 505
>AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens cDNA
FLJ23990 fis, clone HRC08053, highly similar to Homo
sapiens fibroblast growth factor receptor-like 1
(FGFRL1). ).
Length = 440
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 15/204 (7%)
Query: 3055 ILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDI 3114
++P Q+ L G T L C V+G P P +W K+G + R G L +K +
Sbjct: 5 VVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG----LKVKQV 59
Query: 3115 NIDDEGRYSCEATNTHGKASTYARLAVVTD----RTVWEADAKLKRERSAEVEGDYPPQF 3170
+D G Y C+ATN G S L V+ D + D+ + + P+F
Sbjct: 60 EREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRF 119
Query: 3171 TMRLRDRRVQATYP----VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLE 3226
T + RR P VRL C G P P ++W KD + + + + + TL
Sbjct: 120 TQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKK--WTLS 177
Query: 3227 IAPTNLDDGGVYEVTARNNSGAVS 3250
+ +D G Y N +GA++
Sbjct: 178 LKNLRPEDSGKYTCRVSNRAGAIN 201
Score = 62.9 bits (146), Expect = 2e-08
Identities = 68/259 (26%), Positives = 101/259 (38%), Gaps = 47/259 (18%)
Query: 3185 VRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARN 3244
VRL C V G PPP W KDG + R + + L++ +D GVY A N
Sbjct: 17 VRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQ---GLKVKQVEREDAGVYVCKATN 73
Query: 3245 NSGAVSCHCGLVVDKGI---RAYVAPEFCCG----------LEPLY----KLHE------ 3281
G++S + LVV I + + P+ G P + K+
Sbjct: 74 GFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARP 133
Query: 3282 -GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYT 3340
G +R+ V +P +TW +D L R R + L+L + D+G YT
Sbjct: 134 VGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDSGKYT 190
Query: 3341 CTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDT 3400
C SN G + + KV+VI R PV+ P ++ G T
Sbjct: 191 CRVSNRAGAINATYKVDVI-----QRTRSKPVLTG------------THPVNTTVDFGGT 233
Query: 3401 VIIECEVVGDPKPDVYWLR 3419
+C+V D KP + WL+
Sbjct: 234 TSFQCKVRSDVKPVIQWLK 252
Score = 56.4 bits (130), Expect = 2e-06
Identities = 57/239 (23%), Positives = 104/239 (43%), Gaps = 19/239 (7%)
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENS 2772
L+C + G P P W KD + I S G + L G L + ED+G Y CKA N
Sbjct: 19 LQCPVEGDPPPLTMWTKDGRTIHS-GWSRFRVLPQG---LKVKQVEREDAGVYVCKATNG 74
Query: 2773 VWTDQITHFVNFT-----GRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVAR- 2826
+ + + + G+ES + P+ + + A Q R + + +AR
Sbjct: 75 FGSLSVNYTLVVLDDISPGKES-LGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARP 133
Query: 2827 -GGTIGLQVEIRGCPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYT 2884
G ++ L+ G P + W+++ +++T R + +TL+L ++ +SG YT
Sbjct: 134 VGSSVRLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYT 190
Query: 2885 CRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
CR + G ++ + V+Q + KP V+ G + + G + + + + KP
Sbjct: 191 CRVSNRAGAINATYKVDVIQRT--RSKP-VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 246
Score = 52.8 bits (121), Expect = 2e-05
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNK--LKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
GS V+L C P +TW ++ L + RKK TL + N P DS +Y+
Sbjct: 135 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKW----TLSLKNLRPEDSGKYT 190
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C V N GAI+ + + V + P+ T T + T +C++R P I
Sbjct: 191 CRVSNRAGAINATYKVDVIQRTRSKPV-LTGTHPVNTTVDFG-GTTSFQCKVRSDVKPVI 248
Query: 2726 TWFKDDKQIPSDGRYQA 2742
W K + ++GR+ +
Sbjct: 249 QWLK-RVEYGAEGRHNS 264
Score = 48.4 bits (110), Expect = 5e-04
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 3282 GDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTC 3341
G +R+ VE P W +DG + L + L + V DAGVY C
Sbjct: 14 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG----LKVKQVEREDAGVYVC 69
Query: 3342 TASNEVGRASTS-----------GKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKP 3390
A+N G S + GK E +G D +S + P P +P +R+
Sbjct: 70 KATNGFGSLSVNYTLVVLDDISPGK-ESLGPDSSSGGQEDPASQQWARPRFTQPSKMRR- 127
Query: 3391 RSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
R G +V ++C G P+PD+ W++D
Sbjct: 128 RVIARPVGSSVRLKCVASGHPRPDITWMKD 157
Score = 41.1 bits (92), Expect = 0.068
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 3049 RPEFVDILPGQLKILA---GETANLTCSVKGKPVPGVVWMKNGHEVEE-EAGRMTSQFNG 3104
RP F + +++A G + L C G P P + WMK+ + EA +
Sbjct: 116 RPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKK--- 172
Query: 3105 FDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L++K++ +D G+Y+C +N G + ++ V+
Sbjct: 173 -KWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 209
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhesion
molecule splice variant protein.
Length = 1746
Score = 71.3 bits (167), Expect = 6e-11
Identities = 56/191 (29%), Positives = 81/191 (42%), Gaps = 20/191 (10%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDP-TVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
P F R ++ G RV + C V+S P T+TW ++G + L +D +L
Sbjct: 349 PFIQPFEFPRFSI-GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLR 407
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV 2712
+ N + Y+C NE A+ + L V +PP F RD + ++
Sbjct: 408 ISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR-------VPPKFVVQPRDQDGIYGKAVI 460
Query: 2713 LECRIRGQPLPKITW-FKDDKQIPS------DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
L C G P+P I W F +P +GR Q L++G L I + EDSG Y
Sbjct: 461 LNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQV--LSNG--SLLIKHVVEEDSGYY 516
Query: 2766 TCKAENSVWTD 2776
CK N V D
Sbjct: 517 LCKVSNDVGAD 527
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/194 (28%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 2584 RTLSRNSTRKPVFSTFLTDRTAVE-GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK 2642
+ + R ++P+ +T + GS+V L+CSV + D ++WYRNG +L+ R
Sbjct: 55 KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 114
Query: 2643 KLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
++ L + + V SD Y C V + +S ++V I F+ +
Sbjct: 115 TGINH-ENLIMDHMVKSDGGAYQCFVRKDK--LSAQDYVQVVLEDGTPKIISAFSEKVVS 171
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDG--RYQAFYLADG--VCRLAIDNPT 2758
AE + L C ++G PLP ITW DD I G R ++G V L I +
Sbjct: 172 P---AE-PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 227
Query: 2759 PEDSGTYTCKAENS 2772
D G Y C A NS
Sbjct: 228 VRDGGVYRCTANNS 241
Score = 62.1 bits (144), Expect = 3e-08
Identities = 66/289 (22%), Positives = 112/289 (38%), Gaps = 39/289 (13%)
Query: 3076 GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKAST 3135
G P P W+K+ +E +GR G L I++I D G Y CE +N +G A
Sbjct: 2 GHPEPDYRWLKDNMPLEL-SGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKV 56
Query: 3136 YARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSP 3195
RL V P + T+ R + V L+C V G+
Sbjct: 57 IGRLYV-----------------------KQPLKATISPRKVKSSVGSQVSLSCSVTGTE 93
Query: 3196 PPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGL 3255
++SWY++GE ++ + + L + DGG Y+ R + + + +
Sbjct: 94 DQELSWYRNGE-ILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQV 152
Query: 3256 VVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDG--VRLRPSRR 3313
V++ G P+ + + + + V+ P +TW D + S R
Sbjct: 153 VLEDG-----TPKIISAFSEKV-VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHR 206
Query: 3314 AIMTLDRDGQIE--LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIG 3360
+ +G + L +++ RD GVY CTA+N G ++ V G
Sbjct: 207 ISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG 255
Score = 59.3 bits (137), Expect = 2e-07
Identities = 83/352 (23%), Positives = 136/352 (38%), Gaps = 47/352 (13%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
N++ + + NRYG T+ IG L +P I P ++K G +L+
Sbjct: 34 NIRPSDSGSYVCEVSNRYG------TAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLS 86
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHG 3131
CSV G + W +NG + + N + L + + D G Y C
Sbjct: 87 CSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQCFVRKDKL 144
Query: 3132 KASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQV 3191
A Y ++ V+ D T P+ ++ V PV L C V
Sbjct: 145 SAQDYVQV-VLEDGT---------------------PKIISAFSEKVVSPAEPVSLMCNV 182
Query: 3192 IGSPPPKVSWYKDGEEVVYDKRRNKYQ-----DEQFHTLEIAPTNLDDGGVYEVTARNNS 3246
G+P P ++W D + ++ Q L I+ + + DGGVY TA N++
Sbjct: 183 KGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSA 242
Query: 3247 GAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGV 3306
G V + V +G A + P ++ + + G + I V YP + WY++
Sbjct: 243 GVVLYQARINV-RG-PASIRP-----MKNITAI-AGRDTYIHCRVIGYPYYSIKWYKNS- 293
Query: 3307 RLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
L P + + +G ++L+ D G YTC + + STS V V
Sbjct: 294 NLLPFNHRQVAFENNGTLKLSDVQKEV-DEGEYTCNVLVQ-PQLSTSQSVHV 343
Score = 54.8 bits (126), Expect = 5e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 24/196 (12%)
Query: 2595 VFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE-- 2652
+ S F +++ V L C+V + PT+TW + D LK + +IT E
Sbjct: 161 IISAF-SEKVVSPAEPVSLMCNVKGTPLPTITWTLDD---DPILKGGSHRISQMITSEGN 216
Query: 2653 ---VLNAVPS---DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
LN S D Y CT N G + A + V P R +++ +
Sbjct: 217 VVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG--------PASIRPMKNITAI 268
Query: 2707 AENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYT 2766
A + + CR+ G P I W+K+ +P + R AF +G +L+ D D G YT
Sbjct: 269 AGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLS-DVQKEVDEGEYT 326
Query: 2767 CK--AENSVWTDQITH 2780
C + + T Q H
Sbjct: 327 CNVLVQPQLSTSQSVH 342
Score = 48.8 bits (111), Expect = 3e-04
Identities = 68/292 (23%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
+AG + C V G P + W KN + + ++ + NG L + D+ + DEG
Sbjct: 268 IAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNG---TLKLSDVQKEVDEGE 324
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y+C +L +S V PP F R
Sbjct: 325 YTCNVL----------------------VQPQLSTSQSVHVTVKVPP-FIQPFEFPRFSI 361
Query: 3182 TYPVRLTCQVI-GSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEV 3240
V + C V+ G P ++W KDG + + +L I+ +L G Y
Sbjct: 362 GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC 421
Query: 3241 TARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVT 3300
ARN + AV L+V + V P G+ G + ++ E YP +
Sbjct: 422 IARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIY-------GKAVILNCSAEGYPVPTIV 474
Query: 3301 W-YRDGVRLRPSRRAIMTLDRDGQIE---LALAAVTTRDAGVYTCTASNEVG 3348
W + G + P + I R + L + V D+G Y C SN+VG
Sbjct: 475 WKFSKGAGV-PQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 525
Score = 48.0 bits (109), Expect = 6e-04
Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 12/187 (6%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
+R + R P + + TA+ G + C VI ++ WY+N LL +R+ +
Sbjct: 249 ARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFE 306
Query: 2647 GLITLEVLNAVPS-DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
TL++ + D EY+C V + +STS ++ V +PP F
Sbjct: 307 NNGTLKLSDVQKEVDEGEYTCNVLVQ-PQLSTSQSVHV-----TVKVPPFIQPFEFPRFS 360
Query: 2706 LAENELVLECRIRGQPLP-KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
+ + + + C + LP ITW KD + IP + D L I N + +G
Sbjct: 361 IGQ-RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI-DFTSSLRISNLSLMHNGN 418
Query: 2765 YTCKAEN 2771
YTC A N
Sbjct: 419 YTCIARN 425
Score = 46.8 bits (106), Expect = 0.001
Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 22/196 (11%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTW-YRNGVLLDNKLKYRKKLVDGLI--- 2649
P F D+ + G V L CS PT+ W + G + +++ ++G I
Sbjct: 442 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVP---QFQPIALNGRIQVL 498
Query: 2650 ---TLEVLNAVPSDSAEYSCTVENENGA-ISTSANLKVYPSFEASPIPPTFTRSIRDTFH 2705
+L + + V DS Y C V N+ GA +S S L V IP T T
Sbjct: 499 SNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV-------KIPAMITSYPNTTLA 551
Query: 2706 LAENELVLECRIRGQPLPKITWFKDDKQI-PSDGRYQAFYLADG---VCRLAIDNPTPED 2761
+ + C G+ + W K+D+ I P RY G + L I ED
Sbjct: 552 TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVRED 611
Query: 2762 SGTYTCKAENSVWTDQ 2777
SG ++C A NS D+
Sbjct: 612 SGFFSCHAINSYGEDR 627
Score = 46.0 bits (104), Expect = 0.002
Identities = 71/325 (21%), Positives = 127/325 (39%), Gaps = 51/325 (15%)
Query: 2622 DPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANL 2681
+P W ++ + L+ +++K V GL+ + N PSDS Y C V N G L
Sbjct: 5 EPDYRWLKDNMPLELSGRFQKT-VTGLL---IENIRPSDSGSYVCEVSNRYGTAKVIGRL 60
Query: 2682 KVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQ 2741
V +A+ P R ++ + +++ L C + G +++W+++ +I + G+
Sbjct: 61 YVKQPLKATISP----RKVKSS---VGSQVSLSCSVTGTEDQELSWYRNG-EILNPGK-N 111
Query: 2742 AFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKT 2801
L +D+ D G Y C FV +Q VV
Sbjct: 112 VRITGINHENLIMDHMVKSDGGAYQC-------------FVRKDKLSAQDYVQVV----- 153
Query: 2802 RIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTE--VYRN 2858
LE P + ++ V+ + L ++G P + W + + + +R
Sbjct: 154 ------LEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 207
Query: 2859 ARVFVEQG--LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIV 2916
+++ +G + L +S + G+Y C A ++ G V A I V P+ +
Sbjct: 208 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI-------- 259
Query: 2917 GRPEKDILISVGEDINISFRTQGEP 2941
RP K+I G D I R G P
Sbjct: 260 -RPMKNITAIAGRDTYIHCRVIGYP 283
Score = 44.8 bits (101), Expect = 0.006
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 8/73 (10%)
Query: 2710 ELVLECRIRGQPLPKITWFKDDKQIPS----DGRYQAFYLADGVCRLAIDNPTPEDSGTY 2765
++VL C+ G P P + W KD PS DGR F + R EDSG Y
Sbjct: 1054 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV----KAEDSGYY 1109
Query: 2766 TCKAENSVWTDQI 2778
+C A N+ +D+I
Sbjct: 1110 SCIANNNWGSDEI 1122
Score = 44.0 bits (99), Expect = 0.010
Identities = 58/248 (23%), Positives = 99/248 (39%), Gaps = 42/248 (16%)
Query: 2719 GQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQI 2778
G P P W KD+ + GR+Q V L I+N P DSG+Y C+ N T ++
Sbjct: 2 GHPEPDYRWLKDNMPLELSGRFQKT-----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 56
Query: 2779 THFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRG 2838
GR P K I+ + ++S + G + L + G
Sbjct: 57 ------IGRLYVKQP-----LKATISPRKVKS--------------SVGSQVSLSCSVTG 91
Query: 2839 CPTR-VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMN 2897
+ + W R G + +N R+ L + + +++ G Y C D
Sbjct: 92 TEDQELSWYRNG-EILNPGKNVRI-TGINHENLIMDHMVKSDGGAYQCFV-----RKDKL 144
Query: 2898 AAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPKAVPERIPGEPCVV 2957
+A VQ DG P +I EK ++S E +++ +G P P + + +P ++
Sbjct: 145 SAQDYVQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPLP-TITWTLDDDP-IL 200
Query: 2958 DGGNNWVS 2965
GG++ +S
Sbjct: 201 KGGSHRIS 208
Score = 38.7 bits (86), Expect = 0.36
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 3012 NLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLT 3071
NL + +Y V G G SS+ I V P + G + + L
Sbjct: 1002 NLSRNRQYSVWVVAVTSAGRGNSSEI---ITVEPLAKAPARILTFSGTVTTPWMKDIVLP 1058
Query: 3072 CSVKGKPVPGVVWMKNGHEVEEEA---GRMTSQFNGFDCCLTIKDINIDDEGRYSCEATN 3128
C G P P V WMK+ + GR + NG I+ + +D G YSC A N
Sbjct: 1059 CKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG---SFIIRTVKAEDSGYYSCIANN 1115
Query: 3129 THGKASTYARLAV 3141
G L V
Sbjct: 1116 NWGSDEIILNLQV 1128
Score = 37.9 bits (84), Expect = 0.64
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVW-MKNGHEVEEEA-----GRMTSQFN 3103
P+FV + P + G+ L CS +G PVP +VW G V + GR+ N
Sbjct: 442 PKFV-VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 500
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHG 3131
G L IK + +D G Y C+ +N G
Sbjct: 501 G---SLLIKHVVEEDSGYYLCKVSNDVG 525
Score = 37.9 bits (84), Expect = 0.64
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 3187 LTCQVIGSPPPKVSWYKDGEE----VVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
L C+ +G P P V W KD V D RR+ + + F I +D G Y A
Sbjct: 1057 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF---IIRTVKAEDSGYYSCIA 1113
Query: 3243 RNNSGA 3248
NN G+
Sbjct: 1114 NNNWGS 1119
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus protein.
Length = 1236
Score = 71.3 bits (167), Expect = 6e-11
Identities = 83/343 (24%), Positives = 138/343 (40%), Gaps = 45/343 (13%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T+S P + T + G L C + P ++W NGV ++ +
Sbjct: 352 TISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 411
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
+DG T+ N SA Y C NE G + +A + V PP +
Sbjct: 412 IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE------PPRILTPANTLY 464
Query: 2705 HLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+ N +L+C G PLP I WFK K ++ Y+ L I + +G
Sbjct: 465 QVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTG 521
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TYTC A N + +++V ++ + T I +Q P +
Sbjct: 522 TYTCVARNKLGM-----------AKNEV--HLEIKDPTWIVKQ------PEYA------V 556
Query: 2824 VARGGTIGLQVEIRGCPT---RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V RG + + +++ T V WL++ R E+ + R V++ L ++DV++ +S
Sbjct: 557 VQRGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKD--HLVVADVSDDDS 611
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G YTC A + +V +A ++VV P+ P V P D+
Sbjct: 612 GTYTCVANTTLDSVSASAVLSVVAPTPTPA-PVYDVPNPPFDL 653
Score = 71.3 bits (167), Expect = 6e-11
Identities = 75/313 (23%), Positives = 115/313 (36%), Gaps = 39/313 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P + W+ NG +E + + +G + ++
Sbjct: 367 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQE 424
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y C A+N +G A + V+ AE P T+
Sbjct: 425 RSSAVYQCNASNEYGYLLANAFVNVL-----------------AEPPRILTPANTLY--- 464
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+V A P L C GSP P + W+K + + + Y + TLEI D G
Sbjct: 465 -QVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIPVAQKDSTG 521
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y ARN G L + PE+ + G + V+ +
Sbjct: 522 TYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV-------VQRGSMVSFECKVKHDHT 574
Query: 3297 VGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
+ +T W +D L R T+D+D L +A V+ D+G YTC A+ + S S
Sbjct: 575 LSLTVLWLKDNRELPSDER--FTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASA 629
Query: 3355 KVEVIGTDQTSEP 3367
+ V+ T P
Sbjct: 630 VLSVVAPTPTPAP 642
Score = 66.1 bits (154), Expect = 2e-09
Identities = 93/352 (26%), Positives = 141/352 (40%), Gaps = 42/352 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-----YS 2665
+ + C P+ +W RNG D + G TL ++N + AE Y
Sbjct: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL-IINIMSEGKAETYEGVYQ 122
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
CT NE GA + S N+ V PS P +T+ + L + LVL CR G P P
Sbjct: 123 CTARNERGA-AVSNNIVVRPSRS-----PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPP 176
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAE-NSVWTDQITH 2780
I W + Q +P R D L N PED+ Y C A N T Q
Sbjct: 177 IIFWMDNSFQRLPQSERVSQGLNGD----LYFSNVLPEDTREDYICYARFNHTQTIQQKQ 232
Query: 2781 FVNFTGRESQVSPNVVTAEKTRI---ARQSLESRRPHF----GNVLTDYQVARGGTIGLQ 2833
++ + + A + +S R P F GN ++ + RG + L+
Sbjct: 233 PISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNA-SNKEELRGNVLSLE 291
Query: 2834 VEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G PT + W +E + +N V+ + TL + V+E +SG Y C A +A G
Sbjct: 292 CIAEGLPTPIIYWAKEDGMLP---KNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKNALG 347
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ ++ V K A +++++S GED + R G PKP+
Sbjct: 348 AIHHTISVRV--------KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 391
Score = 54.4 bits (125), Expect = 7e-06
Identities = 84/375 (22%), Positives = 147/375 (39%), Gaps = 54/375 (14%)
Query: 3060 LKILAGETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + +G++ L C G P P + WM N + ++ R++ NG D + + D
Sbjct: 155 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG-DLYFS-NVLPEDT 212
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS------AEVEGDYPPQFTM 3172
Y C A H + + V +V E + + S A+ + PP F
Sbjct: 213 REDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLT 272
Query: 3173 ---RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
++ + L C G P P + W K E+ + K R Y++ + TL+I
Sbjct: 273 PEGNASNKEELRGNVLSLECIAEGLPTPIIYWAK--EDGMLPKNRTVYKNFE-KTLQIIH 329
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ D G Y+ A+N GA+ H + +R AP + + L L G++ +
Sbjct: 330 VSEADSGNYQCIAKNALGAI--HHTI----SVRVKAAPYWITAPQNLV-LSPGEDGTLIC 382
Query: 3290 VVEAYPSVGVTWYRDGVRLR-----PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
P ++W +GV + PSR+ +D D + + V R + VY C AS
Sbjct: 383 RANGNPKPRISWLTNGVPIEIAPDDPSRK----IDGD---TIIFSNVQERSSAVYQCNAS 435
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
NE G + V V+ PP +++P + + +P +++
Sbjct: 436 NEYGYLLANAFVNVLAE--------PPRILTP--ANTLYQVIANRP----------ALLD 475
Query: 3405 CEVVGDPKPDVYWLR 3419
C G P P + W +
Sbjct: 476 CAFFGSPLPTIEWFK 490
Score = 50.0 bits (114), Expect = 1e-04
Identities = 79/333 (23%), Positives = 130/333 (39%), Gaps = 50/333 (15%)
Query: 2592 RKPVFST---FLTDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDG 2647
R P F T +++ + G+ + L C P + W + +G+L N+ Y+
Sbjct: 266 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-- 323
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
TL++++ +DS Y C +N GAI + +++V +A+P T +++
Sbjct: 324 --TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV----KAAPYWITAPQNL--VLSPG 375
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
E+ ++ CR G P P+I+W + I P D + DG + N S
Sbjct: 376 EDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRK----IDG-DTIIFSNVQERSSAV 429
Query: 2765 YTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Y C A N FVN V AE RI + N L YQV
Sbjct: 430 YQCNASNEYGYLLANAFVN------------VLAEPPRILTPA---------NTL--YQV 466
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
L G P +EW + G + ++ + V E G TL + + +G Y
Sbjct: 467 IANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTY 523
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIV 2916
TC A + G + + P+ + +P V
Sbjct: 524 TCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV 556
Score = 44.8 bits (101), Expect = 0.006
Identities = 67/274 (24%), Positives = 105/274 (38%), Gaps = 31/274 (11%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP T + +D + + + C+ G PPP SW ++G DK TL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 3226 EIAPTNLDDG------GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
I + +G GVY+ TARN GA + +VV E LEP+ L
Sbjct: 105 II--NIMSEGKAETYEGVYQCTARNERGAAVSN-NIVVRPSRSPLWTKE---KLEPI-TL 157
Query: 3280 HEGDELRISAVVEAYPSVG-----VTWYRDGV-RLRPSRRAIMTLDRDGQIELALAAVTT 3333
G L V+ P +G + W + RL S R L+ D L T
Sbjct: 158 QSGQSL----VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTR 213
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISP--DVPYSKE--PMFIRK 3389
D Y + + V+VI D+ ++ + + S+E P F+
Sbjct: 214 EDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTP 273
Query: 3390 PRSSEARE---GDTVIIECEVVGDPKPDVYWLRD 3420
++ +E G+ + +EC G P P +YW ++
Sbjct: 274 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE 307
Score = 35.9 bits (79), Expect = 2.6
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 15/159 (9%)
Query: 2987 WLIGAEGGARWVELGITPLNSFDAFNLKQGEEYH-FRVTPRNRYGWGESSQTSSSIGVGL 3045
W GA+G A ++ + N + Q + + RN+ G ++ V L
Sbjct: 488 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE-------VHL 540
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPG--VVWMKNGHEVEEEAGRMTSQFN 3103
P ++ P + G + C VK V+W+K+ E+ + R T +
Sbjct: 541 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE-RFTVDKD 599
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L + D++ DD G Y+C A T S A L+VV
Sbjct: 600 H----LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV 634
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 71.3 bits (167), Expect = 6e-11
Identities = 83/343 (24%), Positives = 138/343 (40%), Gaps = 45/343 (13%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T+S P + T + G L C + P ++W NGV ++ +
Sbjct: 352 TISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 411
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
+DG T+ N SA Y C NE G + +A + V PP +
Sbjct: 412 IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE------PPRILTPANTLY 464
Query: 2705 HLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+ N +L+C G PLP I WFK K ++ Y+ L I + +G
Sbjct: 465 QVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTG 521
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TYTC A N + +++V ++ + T I +Q P +
Sbjct: 522 TYTCVARNKLGM-----------AKNEV--HLEIKDPTWIVKQ------PEYA------V 556
Query: 2824 VARGGTIGLQVEIRGCPT---RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V RG + + +++ T V WL++ R E+ + R V++ L ++DV++ +S
Sbjct: 557 VQRGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKD--HLVVADVSDDDS 611
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDI 2923
G YTC A + +V +A ++VV P+ P V P D+
Sbjct: 612 GTYTCVANTTLDSVSASAVLSVVAPTPTPA-PVYDVPNPPFDL 653
Score = 71.3 bits (167), Expect = 6e-11
Identities = 75/313 (23%), Positives = 115/313 (36%), Gaps = 39/313 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P + W+ NG +E + + +G + ++
Sbjct: 367 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQE 424
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y C A+N +G A + V+ AE P T+
Sbjct: 425 RSSAVYQCNASNEYGYLLANAFVNVL-----------------AEPPRILTPANTLY--- 464
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+V A P L C GSP P + W+K + + + Y + TLEI D G
Sbjct: 465 -QVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIPVAQKDSTG 521
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y ARN G L + PE+ + G + V+ +
Sbjct: 522 TYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV-------VQRGSMVSFECKVKHDHT 574
Query: 3297 VGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
+ +T W +D L R T+D+D L +A V+ D+G YTC A+ + S S
Sbjct: 575 LSLTVLWLKDNRELPSDER--FTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASA 629
Query: 3355 KVEVIGTDQTSEP 3367
+ V+ T P
Sbjct: 630 VLSVVAPTPTPAP 642
Score = 66.1 bits (154), Expect = 2e-09
Identities = 93/352 (26%), Positives = 141/352 (40%), Gaps = 42/352 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-----YS 2665
+ + C P+ +W RNG D + G TL ++N + AE Y
Sbjct: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL-IINIMSEGKAETYEGVYQ 122
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
CT NE GA + S N+ V PS P +T+ + L + LVL CR G P P
Sbjct: 123 CTARNERGA-AVSNNIVVRPSRS-----PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPP 176
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAE-NSVWTDQITH 2780
I W + Q +P R D L N PED+ Y C A N T Q
Sbjct: 177 IIFWMDNSFQRLPQSERVSQGLNGD----LYFSNVLPEDTREDYICYARFNHTQTIQQKQ 232
Query: 2781 FVNFTGRESQVSPNVVTAEKTRI---ARQSLESRRPHF----GNVLTDYQVARGGTIGLQ 2833
++ + + A + +S R P F GN ++ + RG + L+
Sbjct: 233 PISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNA-SNKEELRGNVLSLE 291
Query: 2834 VEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G PT + W +E + +N V+ + TL + V+E +SG Y C A +A G
Sbjct: 292 CIAEGLPTPIIYWAKEDGMLP---KNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKNALG 347
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ ++ V K A +++++S GED + R G PKP+
Sbjct: 348 AIHHTISVRV--------KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 391
Score = 54.4 bits (125), Expect = 7e-06
Identities = 84/375 (22%), Positives = 147/375 (39%), Gaps = 54/375 (14%)
Query: 3060 LKILAGETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + +G++ L C G P P + WM N + ++ R++ NG D + + D
Sbjct: 155 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG-DLYFS-NVLPEDT 212
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS------AEVEGDYPPQFTM 3172
Y C A H + + V +V E + + S A+ + PP F
Sbjct: 213 REDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLT 272
Query: 3173 ---RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
++ + L C G P P + W K E+ + K R Y++ + TL+I
Sbjct: 273 PEGNASNKEELRGNVLSLECIAEGLPTPIIYWAK--EDGMLPKNRTVYKNFE-KTLQIIH 329
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ D G Y+ A+N GA+ H + +R AP + + L L G++ +
Sbjct: 330 VSEADSGNYQCIAKNALGAI--HHTI----SVRVKAAPYWITAPQNLV-LSPGEDGTLIC 382
Query: 3290 VVEAYPSVGVTWYRDGVRLR-----PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
P ++W +GV + PSR+ +D D + + V R + VY C AS
Sbjct: 383 RANGNPKPRISWLTNGVPIEIAPDDPSRK----IDGD---TIIFSNVQERSSAVYQCNAS 435
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
NE G + V V+ PP +++P + + +P +++
Sbjct: 436 NEYGYLLANAFVNVLAE--------PPRILTP--ANTLYQVIANRP----------ALLD 475
Query: 3405 CEVVGDPKPDVYWLR 3419
C G P P + W +
Sbjct: 476 CAFFGSPLPTIEWFK 490
Score = 50.0 bits (114), Expect = 1e-04
Identities = 79/333 (23%), Positives = 130/333 (39%), Gaps = 50/333 (15%)
Query: 2592 RKPVFST---FLTDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDG 2647
R P F T +++ + G+ + L C P + W + +G+L N+ Y+
Sbjct: 266 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-- 323
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
TL++++ +DS Y C +N GAI + +++V +A+P T +++
Sbjct: 324 --TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV----KAAPYWITAPQNL--VLSPG 375
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
E+ ++ CR G P P+I+W + I P D + DG + N S
Sbjct: 376 EDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRK----IDG-DTIIFSNVQERSSAV 429
Query: 2765 YTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Y C A N FVN V AE RI + N L YQV
Sbjct: 430 YQCNASNEYGYLLANAFVN------------VLAEPPRILTPA---------NTL--YQV 466
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
L G P +EW + G + ++ + V E G TL + + +G Y
Sbjct: 467 IANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTY 523
Query: 2884 TCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIV 2916
TC A + G + + P+ + +P V
Sbjct: 524 TCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV 556
Score = 44.8 bits (101), Expect = 0.006
Identities = 67/274 (24%), Positives = 105/274 (38%), Gaps = 31/274 (11%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP T + +D + + + C+ G PPP SW ++G DK TL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 3226 EIAPTNLDDG------GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
I + +G GVY+ TARN GA + +VV E LEP+ L
Sbjct: 105 II--NIMSEGKAETYEGVYQCTARNERGAAVSN-NIVVRPSRSPLWTKE---KLEPI-TL 157
Query: 3280 HEGDELRISAVVEAYPSVG-----VTWYRDGV-RLRPSRRAIMTLDRDGQIELALAAVTT 3333
G L V+ P +G + W + RL S R L+ D L T
Sbjct: 158 QSGQSL----VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTR 213
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISP--DVPYSKE--PMFIRK 3389
D Y + + V+VI D+ ++ + + S+E P F+
Sbjct: 214 EDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTP 273
Query: 3390 PRSSEARE---GDTVIIECEVVGDPKPDVYWLRD 3420
++ +E G+ + +EC G P P +YW ++
Sbjct: 274 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE 307
Score = 35.9 bits (79), Expect = 2.6
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 15/159 (9%)
Query: 2987 WLIGAEGGARWVELGITPLNSFDAFNLKQGEEYH-FRVTPRNRYGWGESSQTSSSIGVGL 3045
W GA+G A ++ + N + Q + + RN+ G ++ V L
Sbjct: 488 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE-------VHL 540
Query: 3046 AGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPG--VVWMKNGHEVEEEAGRMTSQFN 3103
P ++ P + G + C VK V+W+K+ E+ + R T +
Sbjct: 541 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE-RFTVDKD 599
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
L + D++ DD G Y+C A T S A L+VV
Sbjct: 600 H----LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV 634
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 70.9 bits (166), Expect = 7e-11
Identities = 79/302 (26%), Positives = 124/302 (41%), Gaps = 39/302 (12%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+ PV +T L A+ C+V S P ++W RN +L+ R + + L
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILI-KLFDTRYSIRENGQLL 84
Query: 2652 EVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+L+ SD Y CT N GA+ + L+V + P TR + + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV-------KMKPKITRPPINVKIIEGLK 137
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
VL C G P P ++W K D + + R L G L I N ED+G Y C A+
Sbjct: 138 AVLPCTTMGNPKPSVSWIKGDSPLRENSRIAV--LESG--SLRIHNVQKEDAGQYRCVAK 193
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS+ T + E +V ++ A ES FG+ +T + A G +
Sbjct: 194 NSLG----TAYSKVVKLEVEVFARILRAP---------ESHNVTFGSFVTLHCTATGIPV 240
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
PT + W+ G +V+ + + V+ + L + T+ GLYTC A +
Sbjct: 241 ---------PT-ITWIENGNAVSS--GSIQESVKDRVIDSRL-QLFITKPGLYTCIATNK 287
Query: 2891 HG 2892
HG
Sbjct: 288 HG 289
Score = 58.4 bits (135), Expect = 4e-07
Identities = 75/294 (25%), Positives = 119/294 (40%), Gaps = 38/294 (12%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L E A C+V+ P P + W +N ++ R + + NG LTI + D+G Y
Sbjct: 40 LVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQ--LLTILSVEDSDDGIY 97
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A N G A V + K K R P +++ + ++A
Sbjct: 98 CCTANNGVGGA--------VESCGALQVKMKPKITR---------PPINVKIIEG-LKAV 139
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
P C +G+P P VSW K G+ + + R + +L I +D G Y A
Sbjct: 140 LP----CTTMGNPKPSVSWIK-GDSPLRENSRIAVLES--GSLRIHNVQKEDAGQYRCVA 192
Query: 3243 RNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G A S L V+ R APE + + G + + P +TW
Sbjct: 193 KNSLGTAYSKVVKLEVEVFARILRAPE-------SHNVTFGSFVTLHCTATGIPVPTITW 245
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+G + S +I +D I+ L T+ G+YTC A+N+ G ++ K
Sbjct: 246 IENGNAV--SSGSIQESVKDRVIDSRLQLFITK-PGLYTCIATNKHGEKFSTAK 296
Score = 50.4 bits (115), Expect = 1e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 24/154 (15%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP LE + L E + VE+YP ++W R+ + ++ ++ +GQ+
Sbjct: 27 APVITTPLETVDALVE-EVATFMCAVESYPQPEISWTRNKILIKLFDTRY-SIRENGQL- 83
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +V D G+Y CTA+N VG G VE G Q +P
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVG-----GAVESCGALQV----------------KMKPK 122
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
R P + + EG ++ C +G+PKP V W++
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIK 156
Score = 48.4 bits (110), Expect = 5e-04
Identities = 57/233 (24%), Positives = 91/233 (39%), Gaps = 34/233 (14%)
Query: 3189 CQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C V P P++SW ++ + ++D R + ++ Q T+ ++ + DDG +Y TA N G
Sbjct: 49 CAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTI-LSVEDSDDG-IYCCTANNGVG 106
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
CG + K P K+ EG + + P V+W +
Sbjct: 107 GAVESCGALQVKMKPKITRPPI------NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSP 160
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
LR + R I L+ L + V DAG Y C A N +G A + +V+ +
Sbjct: 161 LRENSR-IAVLESG---SLRIHNVQKEDAGQYRCVAKNSLGTAYS----KVVKLEVEVFA 212
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RI +R P S G V + C G P P + W+ +
Sbjct: 213 RI-----------------LRAPESHNVTFGSFVTLHCTATGIPVPTITWIEN 248
Score = 47.6 bits (108), Expect = 8e-04
Identities = 39/165 (23%), Positives = 64/165 (38%), Gaps = 13/165 (7%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW+ G + + S N+++ + +R +N G S + V
Sbjct: 153 SWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV-- 210
Query: 3046 AGDRPEFVDIL--PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
F IL P + G L C+ G PVP + W++NG+ V + + + +
Sbjct: 211 ------FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDR 264
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVW 3148
D L + I G Y+C ATN HG+ + A+ A W
Sbjct: 265 VIDSRL---QLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEW 306
Score = 44.0 bits (99), Expect = 0.010
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +KI+ G A L C+ G P P V W+K + E + R+ +G L I ++
Sbjct: 127 PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS-RIAVLESG---SLRIHNVQK 182
Query: 3117 DDEGRYSCEATNTHGKA 3133
+D G+Y C A N+ G A
Sbjct: 183 EDAGQYRCVAKNSLGTA 199
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGR 2739
L + E P P T + L E C + P P+I+W ++ I D R
Sbjct: 15 LVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR 74
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
Y + + L I + D G Y C A N V
Sbjct: 75 YS---IRENGQLLTILSVEDSDDGIYCCTANNGV 105
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 70.9 bits (166), Expect = 7e-11
Identities = 79/302 (26%), Positives = 124/302 (41%), Gaps = 39/302 (12%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+ PV +T L A+ C+V S P ++W RN +L+ R + + L
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILI-KLFDTRYSIRENGQLL 84
Query: 2652 EVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+L+ SD Y CT N GA+ + L+V + P TR + + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV-------KMKPKITRPPINVKIIEGLK 137
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
VL C G P P ++W K D + + R L G L I N ED+G Y C A+
Sbjct: 138 AVLPCTTMGNPKPSVSWIKGDSPLRENSRIAV--LESG--SLRIHNVQKEDAGQYRCVAK 193
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS+ T + E +V ++ A ES FG+ +T + A G +
Sbjct: 194 NSLG----TAYSKVVKLEVEVFARILRAP---------ESHNVTFGSFVTLHCTATGIPV 240
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
PT + W+ G +V+ + + V+ + L + T+ GLYTC A +
Sbjct: 241 ---------PT-ITWIENGNAVSS--GSIQESVKDRVIDSRL-QLFITKPGLYTCIATNK 287
Query: 2891 HG 2892
HG
Sbjct: 288 HG 289
Score = 58.4 bits (135), Expect = 4e-07
Identities = 75/294 (25%), Positives = 119/294 (40%), Gaps = 38/294 (12%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L E A C+V+ P P + W +N ++ R + + NG LTI + D+G Y
Sbjct: 40 LVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQ--LLTILSVEDSDDGIY 97
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A N G A V + K K R P +++ + ++A
Sbjct: 98 CCTANNGVGGA--------VESCGALQVKMKPKITR---------PPINVKIIEG-LKAV 139
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
P C +G+P P VSW K G+ + + R + +L I +D G Y A
Sbjct: 140 LP----CTTMGNPKPSVSWIK-GDSPLRENSRIAVLES--GSLRIHNVQKEDAGQYRCVA 192
Query: 3243 RNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G A S L V+ R APE + + G + + P +TW
Sbjct: 193 KNSLGTAYSKVVKLEVEVFARILRAPE-------SHNVTFGSFVTLHCTATGIPVPTITW 245
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+G + S +I +D I+ L T+ G+YTC A+N+ G ++ K
Sbjct: 246 IENGNAV--SSGSIQESVKDRVIDSRLQLFITK-PGLYTCIATNKHGEKFSTAK 296
Score = 50.4 bits (115), Expect = 1e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 24/154 (15%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP LE + L E + VE+YP ++W R+ + ++ ++ +GQ+
Sbjct: 27 APVITTPLETVDALVE-EVATFMCAVESYPQPEISWTRNKILIKLFDTRY-SIRENGQL- 83
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +V D G+Y CTA+N VG G VE G Q +P
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVG-----GAVESCGALQV----------------KMKPK 122
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
R P + + EG ++ C +G+PKP V W++
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIK 156
Score = 48.4 bits (110), Expect = 5e-04
Identities = 57/233 (24%), Positives = 91/233 (39%), Gaps = 34/233 (14%)
Query: 3189 CQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C V P P++SW ++ + ++D R + ++ Q T+ ++ + DDG +Y TA N G
Sbjct: 49 CAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTI-LSVEDSDDG-IYCCTANNGVG 106
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
CG + K P K+ EG + + P V+W +
Sbjct: 107 GAVESCGALQVKMKPKITRPPI------NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSP 160
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
LR + R I L+ L + V DAG Y C A N +G A + +V+ +
Sbjct: 161 LRENSR-IAVLESG---SLRIHNVQKEDAGQYRCVAKNSLGTAYS----KVVKLEVEVFA 212
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RI +R P S G V + C G P P + W+ +
Sbjct: 213 RI-----------------LRAPESHNVTFGSFVTLHCTATGIPVPTITWIEN 248
Score = 45.6 bits (103), Expect = 0.003
Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 13/157 (8%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW+ G + + S N+++ + +R +N G S + V
Sbjct: 153 SWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV-- 210
Query: 3046 AGDRPEFVDIL--PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
F IL P + G L C+ G PVP + W++NG+ V + + + +
Sbjct: 211 ------FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDR 264
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
D L + I G Y+C ATN HG+ + A+ A
Sbjct: 265 VIDSRL---QLFITKPGLYTCIATNKHGEKFSTAKAA 298
Score = 44.0 bits (99), Expect = 0.010
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +KI+ G A L C+ G P P V W+K + E + R+ +G L I ++
Sbjct: 127 PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS-RIAVLESG---SLRIHNVQK 182
Query: 3117 DDEGRYSCEATNTHGKA 3133
+D G+Y C A N+ G A
Sbjct: 183 EDAGQYRCVAKNSLGTA 199
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGR 2739
L + E P P T + L E C + P P+I+W ++ I D R
Sbjct: 15 LVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR 74
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
Y + + L I + D G Y C A N V
Sbjct: 75 YS---IRENGQLLTILSVEDSDDGIYCCTANNGV 105
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 70.9 bits (166), Expect = 7e-11
Identities = 79/302 (26%), Positives = 124/302 (41%), Gaps = 39/302 (12%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+ PV +T L A+ C+V S P ++W RN +L+ R + + L
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILI-KLFDTRYSIRENGQLL 84
Query: 2652 EVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+L+ SD Y CT N GA+ + L+V + P TR + + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV-------KMKPKITRPPINVKIIEGLK 137
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
VL C G P P ++W K D + + R L G L I N ED+G Y C A+
Sbjct: 138 AVLPCTTMGNPKPSVSWIKGDSPLRENSRIAV--LESG--SLRIHNVQKEDAGQYRCVAK 193
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS+ T + E +V ++ A ES FG+ +T + A G +
Sbjct: 194 NSLG----TAYSKVVKLEVEVFARILRAP---------ESHNVTFGSFVTLHCTATGIPV 240
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
PT + W+ G +V+ + + V+ + L + T+ GLYTC A +
Sbjct: 241 ---------PT-ITWIENGNAVSS--GSIQESVKDRVIDSRL-QLFITKPGLYTCIATNK 287
Query: 2891 HG 2892
HG
Sbjct: 288 HG 289
Score = 58.4 bits (135), Expect = 4e-07
Identities = 75/294 (25%), Positives = 119/294 (40%), Gaps = 38/294 (12%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L E A C+V+ P P + W +N ++ R + + NG LTI + D+G Y
Sbjct: 40 LVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQ--LLTILSVEDSDDGIY 97
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A N G A V + K K R P +++ + ++A
Sbjct: 98 CCTANNGVGGA--------VESCGALQVKMKPKITR---------PPINVKIIEG-LKAV 139
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
P C +G+P P VSW K G+ + + R + +L I +D G Y A
Sbjct: 140 LP----CTTMGNPKPSVSWIK-GDSPLRENSRIAVLES--GSLRIHNVQKEDAGQYRCVA 192
Query: 3243 RNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G A S L V+ R APE + + G + + P +TW
Sbjct: 193 KNSLGTAYSKVVKLEVEVFARILRAPE-------SHNVTFGSFVTLHCTATGIPVPTITW 245
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+G + S +I +D I+ L T+ G+YTC A+N+ G ++ K
Sbjct: 246 IENGNAV--SSGSIQESVKDRVIDSRLQLFITK-PGLYTCIATNKHGEKFSTAK 296
Score = 50.4 bits (115), Expect = 1e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 24/154 (15%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP LE + L E + VE+YP ++W R+ + ++ ++ +GQ+
Sbjct: 27 APVITTPLETVDALVE-EVATFMCAVESYPQPEISWTRNKILIKLFDTRY-SIRENGQL- 83
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +V D G+Y CTA+N VG G VE G Q +P
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVG-----GAVESCGALQV----------------KMKPK 122
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
R P + + EG ++ C +G+PKP V W++
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIK 156
Score = 48.4 bits (110), Expect = 5e-04
Identities = 57/233 (24%), Positives = 91/233 (39%), Gaps = 34/233 (14%)
Query: 3189 CQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C V P P++SW ++ + ++D R + ++ Q T+ ++ + DDG +Y TA N G
Sbjct: 49 CAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTI-LSVEDSDDG-IYCCTANNGVG 106
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
CG + K P K+ EG + + P V+W +
Sbjct: 107 GAVESCGALQVKMKPKITRPPI------NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSP 160
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
LR + R I L+ L + V DAG Y C A N +G A + +V+ +
Sbjct: 161 LRENSR-IAVLESG---SLRIHNVQKEDAGQYRCVAKNSLGTAYS----KVVKLEVEVFA 212
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RI +R P S G V + C G P P + W+ +
Sbjct: 213 RI-----------------LRAPESHNVTFGSFVTLHCTATGIPVPTITWIEN 248
Score = 45.6 bits (103), Expect = 0.003
Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 13/157 (8%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW+ G + + S N+++ + +R +N G S + V
Sbjct: 153 SWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV-- 210
Query: 3046 AGDRPEFVDIL--PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
F IL P + G L C+ G PVP + W++NG+ V + + + +
Sbjct: 211 ------FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDR 264
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
D L + I G Y+C ATN HG+ + A+ A
Sbjct: 265 VIDSRL---QLFITKPGLYTCIATNKHGEKFSTAKAA 298
Score = 44.0 bits (99), Expect = 0.010
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +KI+ G A L C+ G P P V W+K + E + R+ +G L I ++
Sbjct: 127 PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS-RIAVLESG---SLRIHNVQK 182
Query: 3117 DDEGRYSCEATNTHGKA 3133
+D G+Y C A N+ G A
Sbjct: 183 EDAGQYRCVAKNSLGTA 199
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGR 2739
L + E P P T + L E C + P P+I+W ++ I D R
Sbjct: 15 LVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR 74
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
Y + + L I + D G Y C A N V
Sbjct: 75 YS---IRENGQLLTILSVEDSDDGIYCCTANNGV 105
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 70.9 bits (166), Expect = 7e-11
Identities = 79/302 (26%), Positives = 124/302 (41%), Gaps = 39/302 (12%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+ PV +T L A+ C+V S P ++W RN +L+ R + + L
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILI-KLFDTRYSIRENGQLL 84
Query: 2652 EVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+L+ SD Y CT N GA+ + L+V + P TR + + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV-------KMKPKITRPPINVKIIEGLK 137
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
VL C G P P ++W K D + + R L G L I N ED+G Y C A+
Sbjct: 138 AVLPCTTMGNPKPSVSWIKGDSPLRENSRIAV--LESG--SLRIHNVQKEDAGQYRCVAK 193
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS+ T + E +V ++ A ES FG+ +T + A G +
Sbjct: 194 NSLG----TAYSKVVKLEVEVFARILRAP---------ESHNVTFGSFVTLHCTATGIPV 240
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
PT + W+ G +V+ + + V+ + L + T+ GLYTC A +
Sbjct: 241 ---------PT-ITWIENGNAVSS--GSIQESVKDRVIDSRL-QLFITKPGLYTCIATNK 287
Query: 2891 HG 2892
HG
Sbjct: 288 HG 289
Score = 58.4 bits (135), Expect = 4e-07
Identities = 75/294 (25%), Positives = 119/294 (40%), Gaps = 38/294 (12%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L E A C+V+ P P + W +N ++ R + + NG LTI + D+G Y
Sbjct: 40 LVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQ--LLTILSVEDSDDGIY 97
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A N G A V + K K R P +++ + ++A
Sbjct: 98 CCTANNGVGGA--------VESCGALQVKMKPKITR---------PPINVKIIEG-LKAV 139
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
P C +G+P P VSW K G+ + + R + +L I +D G Y A
Sbjct: 140 LP----CTTMGNPKPSVSWIK-GDSPLRENSRIAVLES--GSLRIHNVQKEDAGQYRCVA 192
Query: 3243 RNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G A S L V+ R APE + + G + + P +TW
Sbjct: 193 KNSLGTAYSKVVKLEVEVFARILRAPE-------SHNVTFGSFVTLHCTATGIPVPTITW 245
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+G + S +I +D I+ L T+ G+YTC A+N+ G ++ K
Sbjct: 246 IENGNAV--SSGSIQESVKDRVIDSRLQLFITK-PGLYTCIATNKHGEKFSTAK 296
Score = 50.4 bits (115), Expect = 1e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 24/154 (15%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP LE + L E + VE+YP ++W R+ + ++ ++ +GQ+
Sbjct: 27 APVITTPLETVDALVE-EVATFMCAVESYPQPEISWTRNKILIKLFDTRY-SIRENGQL- 83
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +V D G+Y CTA+N VG G VE G Q +P
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVG-----GAVESCGALQV----------------KMKPK 122
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
R P + + EG ++ C +G+PKP V W++
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIK 156
Score = 48.4 bits (110), Expect = 5e-04
Identities = 57/233 (24%), Positives = 91/233 (39%), Gaps = 34/233 (14%)
Query: 3189 CQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C V P P++SW ++ + ++D R + ++ Q T+ ++ + DDG +Y TA N G
Sbjct: 49 CAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTI-LSVEDSDDG-IYCCTANNGVG 106
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
CG + K P K+ EG + + P V+W +
Sbjct: 107 GAVESCGALQVKMKPKITRPPI------NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSP 160
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
LR + R I L+ L + V DAG Y C A N +G A + +V+ +
Sbjct: 161 LRENSR-IAVLESG---SLRIHNVQKEDAGQYRCVAKNSLGTAYS----KVVKLEVEVFA 212
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RI +R P S G V + C G P P + W+ +
Sbjct: 213 RI-----------------LRAPESHNVTFGSFVTLHCTATGIPVPTITWIEN 248
Score = 45.6 bits (103), Expect = 0.003
Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 13/157 (8%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW+ G + + S N+++ + +R +N G S + V
Sbjct: 153 SWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV-- 210
Query: 3046 AGDRPEFVDIL--PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
F IL P + G L C+ G PVP + W++NG+ V + + + +
Sbjct: 211 ------FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDR 264
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
D L + I G Y+C ATN HG+ + A+ A
Sbjct: 265 VIDSRL---QLFITKPGLYTCIATNKHGEKFSTAKAA 298
Score = 44.0 bits (99), Expect = 0.010
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +KI+ G A L C+ G P P V W+K + E + R+ +G L I ++
Sbjct: 127 PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS-RIAVLESG---SLRIHNVQK 182
Query: 3117 DDEGRYSCEATNTHGKA 3133
+D G+Y C A N+ G A
Sbjct: 183 EDAGQYRCVAKNSLGTA 199
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGR 2739
L + E P P T + L E C + P P+I+W ++ I D R
Sbjct: 15 LVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR 74
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
Y + + L I + D G Y C A N V
Sbjct: 75 YS---IRENGQLLTILSVEDSDDGIYCCTANNGV 105
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 70.9 bits (166), Expect = 7e-11
Identities = 79/302 (26%), Positives = 124/302 (41%), Gaps = 39/302 (12%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+ PV +T L A+ C+V S P ++W RN +L+ R + + L
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILI-KLFDTRYSIRENGQLL 84
Query: 2652 EVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+L+ SD Y CT N GA+ + L+V + P TR + + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV-------KMKPKITRPPINVKIIEGLK 137
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
VL C G P P ++W K D + + R L G L I N ED+G Y C A+
Sbjct: 138 AVLPCTTMGNPKPSVSWIKGDSPLRENSRIAV--LESG--SLRIHNVQKEDAGQYRCVAK 193
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS+ T + E +V ++ A ES FG+ +T + A G +
Sbjct: 194 NSLG----TAYSKVVKLEVEVFARILRAP---------ESHNVTFGSFVTLHCTATGIPV 240
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
PT + W+ G +V+ + + V+ + L + T+ GLYTC A +
Sbjct: 241 ---------PT-ITWIENGNAVSS--GSIQESVKDRVIDSRL-QLFITKPGLYTCIATNK 287
Query: 2891 HG 2892
HG
Sbjct: 288 HG 289
Score = 58.4 bits (135), Expect = 4e-07
Identities = 75/294 (25%), Positives = 119/294 (40%), Gaps = 38/294 (12%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L E A C+V+ P P + W +N ++ R + + NG LTI + D+G Y
Sbjct: 40 LVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQ--LLTILSVEDSDDGIY 97
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A N G A V + K K R P +++ + ++A
Sbjct: 98 CCTANNGVGGA--------VESCGALQVKMKPKITR---------PPINVKIIEG-LKAV 139
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
P C +G+P P VSW K G+ + + R + +L I +D G Y A
Sbjct: 140 LP----CTTMGNPKPSVSWIK-GDSPLRENSRIAVLES--GSLRIHNVQKEDAGQYRCVA 192
Query: 3243 RNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G A S L V+ R APE + + G + + P +TW
Sbjct: 193 KNSLGTAYSKVVKLEVEVFARILRAPE-------SHNVTFGSFVTLHCTATGIPVPTITW 245
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGK 3355
+G + S +I +D I+ L T+ G+YTC A+N+ G ++ K
Sbjct: 246 IENGNAV--SSGSIQESVKDRVIDSRLQLFITK-PGLYTCIATNKHGEKFSTAK 296
Score = 50.4 bits (115), Expect = 1e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 24/154 (15%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP LE + L E + VE+YP ++W R+ + ++ ++ +GQ+
Sbjct: 27 APVITTPLETVDALVE-EVATFMCAVESYPQPEISWTRNKILIKLFDTRY-SIRENGQL- 83
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +V D G+Y CTA+N VG G VE G Q +P
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVG-----GAVESCGALQV----------------KMKPK 122
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
R P + + EG ++ C +G+PKP V W++
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIK 156
Score = 48.4 bits (110), Expect = 5e-04
Identities = 57/233 (24%), Positives = 91/233 (39%), Gaps = 34/233 (14%)
Query: 3189 CQVIGSPPPKVSWYKDGEEV-VYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSG 3247
C V P P++SW ++ + ++D R + ++ Q T+ ++ + DDG +Y TA N G
Sbjct: 49 CAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTI-LSVEDSDDG-IYCCTANNGVG 106
Query: 3248 AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVR 3307
CG + K P K+ EG + + P V+W +
Sbjct: 107 GAVESCGALQVKMKPKITRPPI------NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSP 160
Query: 3308 LRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEP 3367
LR + R I L+ L + V DAG Y C A N +G A + +V+ +
Sbjct: 161 LRENSR-IAVLESG---SLRIHNVQKEDAGQYRCVAKNSLGTAYS----KVVKLEVEVFA 212
Query: 3368 RIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
RI +R P S G V + C G P P + W+ +
Sbjct: 213 RI-----------------LRAPESHNVTFGSFVTLHCTATGIPVPTITWIEN 248
Score = 45.6 bits (103), Expect = 0.003
Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 13/157 (8%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW+ G + + S N+++ + +R +N G S + V
Sbjct: 153 SWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV-- 210
Query: 3046 AGDRPEFVDIL--PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
F IL P + G L C+ G PVP + W++NG+ V + + + +
Sbjct: 211 ------FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDR 264
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLA 3140
D L + I G Y+C ATN HG+ + A+ A
Sbjct: 265 VIDSRL---QLFITKPGLYTCIATNKHGEKFSTAKAA 298
Score = 44.0 bits (99), Expect = 0.010
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +KI+ G A L C+ G P P V W+K + E + R+ +G L I ++
Sbjct: 127 PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS-RIAVLESG---SLRIHNVQK 182
Query: 3117 DDEGRYSCEATNTHGKA 3133
+D G+Y C A N+ G A
Sbjct: 183 EDAGQYRCVAKNSLGTA 199
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGR 2739
L + E P P T + L E C + P P+I+W ++ I D R
Sbjct: 15 LVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR 74
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
Y + + L I + D G Y C A N V
Sbjct: 75 YS---IRENGQLLTILSVEDSDDGIYCCTANNGV 105
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 70.9 bits (166), Expect = 7e-11
Identities = 79/302 (26%), Positives = 124/302 (41%), Gaps = 39/302 (12%)
Query: 2592 RKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITL 2651
+ PV +T L A+ C+V S P ++W RN +L+ R + + L
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILI-KLFDTRYSIRENGQLL 84
Query: 2652 EVLNAVPSDSAEYSCTVENE-NGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
+L+ SD Y CT N GA+ + L+V + P TR + + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV-------KMKPKITRPPINVKIIEGLK 137
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAE 2770
VL C G P P ++W K D + + R L G L I N ED+G Y C A+
Sbjct: 138 AVLPCTTMGNPKPSVSWIKGDSPLRENSRIAV--LESG--SLRIHNVQKEDAGQYRCVAK 193
Query: 2771 NSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTI 2830
NS+ T + E +V ++ A ES FG+ +T + A G +
Sbjct: 194 NSLG----TAYSKVVKLEVEVFARILRAP---------ESHNVTFGSFVTLHCTATGIPV 240
Query: 2831 GLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSA 2890
PT + W+ G +V+ + + V+ + L + T+ GLYTC A +
Sbjct: 241 ---------PT-ITWIENGNAVSS--GSIQESVKDRVIDSRL-QLFITKPGLYTCIATNK 287
Query: 2891 HG 2892
HG
Sbjct: 288 HG 289
Score = 60.5 bits (140), Expect = 1e-07
Identities = 79/308 (25%), Positives = 126/308 (40%), Gaps = 39/308 (12%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRY 3122
L E A C+V+ P P + W +N ++ R + + NG LTI + D+G Y
Sbjct: 40 LVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQ--LLTILSVEDSDDGIY 97
Query: 3123 SCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQAT 3182
C A N G A V + K K R P +++ + ++A
Sbjct: 98 CCTANNGVGGA--------VESCGALQVKMKPKITR---------PPINVKIIEG-LKAV 139
Query: 3183 YPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTA 3242
P C +G+P P VSW K G+ + + R + +L I +D G Y A
Sbjct: 140 LP----CTTMGNPKPSVSWIK-GDSPLRENSRIAVLES--GSLRIHNVQKEDAGQYRCVA 192
Query: 3243 RNNSG-AVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTW 3301
+N+ G A S L V+ R APE + + G + + P +TW
Sbjct: 193 KNSLGTAYSKVVKLEVEVFARILRAPE-------SHNVTFGSFVTLHCTATGIPVPTITW 245
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVG-RASTSGKVEVIG 3360
+G + S +I +D I+ L T+ G+YTC A+N+ G + ST+ I
Sbjct: 246 IENGNAV--SSGSIQESVKDRVIDSRLQLFITK-PGLYTCIATNKHGEKFSTAKAAATIS 302
Query: 3361 TDQTSEPR 3368
+ S+P+
Sbjct: 303 IAEWSKPQ 310
Score = 50.8 bits (116), Expect = 8e-05
Identities = 42/182 (23%), Positives = 70/182 (38%), Gaps = 13/182 (7%)
Query: 2986 SWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGL 3045
SW+ G + + S N+++ + +R +N G S + V
Sbjct: 153 SWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV-- 210
Query: 3046 AGDRPEFVDIL--PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFN 3103
F IL P + G L C+ G PVP + W++NG+ V + + + +
Sbjct: 211 ------FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDR 264
Query: 3104 GFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
D L + I G Y+C ATN HG+ + A+ A W K + A+
Sbjct: 265 VIDSRL---QLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYR 321
Query: 3164 GD 3165
G+
Sbjct: 322 GE 323
Score = 50.4 bits (115), Expect = 1e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 24/154 (15%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIE 3325
AP LE + L E + VE+YP ++W R+ + ++ ++ +GQ+
Sbjct: 27 APVITTPLETVDALVE-EVATFMCAVESYPQPEISWTRNKILIKLFDTRY-SIRENGQL- 83
Query: 3326 LALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPM 3385
L + +V D G+Y CTA+N VG G VE G Q +P
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVG-----GAVESCGALQV----------------KMKPK 122
Query: 3386 FIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLR 3419
R P + + EG ++ C +G+PKP V W++
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIK 156
Score = 44.0 bits (99), Expect = 0.010
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P +KI+ G A L C+ G P P V W+K + E + R+ +G L I ++
Sbjct: 127 PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS-RIAVLESG---SLRIHNVQK 182
Query: 3117 DDEGRYSCEATNTHGKA 3133
+D G+Y C A N+ G A
Sbjct: 183 EDAGQYRCVAKNSLGTA 199
Score = 35.1 bits (77), Expect = 4.5
Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query: 2681 LKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGR 2739
L + E P P T + L E C + P P+I+W ++ I D R
Sbjct: 15 LVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR 74
Query: 2740 YQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
Y + + L I + D G Y C A N V
Sbjct: 75 YS---IRENGQLLTILSVEDSDDGIYCCTANNGV 105
>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
delta protein.
Length = 1912
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
Length = 1506
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosphatase
receptor type D protein.
Length = 1912
Score = 70.5 bits (165), Expect = 1e-10
Identities = 84/341 (24%), Positives = 124/341 (36%), Gaps = 37/341 (10%)
Query: 2586 LSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV 2645
L ++ P F+ D+T V G C P + W + G + N+ +
Sbjct: 16 LRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFD 75
Query: 2646 DG---LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRD 2702
DG ++ ++ L P D A Y C N G IS S L V + PT +
Sbjct: 76 DGSGSVLRIQPLRT-PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQL 134
Query: 2703 TFHLAENELVLECRIRGQPLPKITWFKDDKQIP---SDGRYQAF---YLADGVCR--LAI 2754
+ C G P P+ITWFKD + ++GR + + R L I
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 2755 DNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPH 2814
+ D G Y C A NS G N+ E + R P
Sbjct: 195 EQSEESDQGKYECVATNS------------AGTRYSAPANLYVRELREVRRVP-----PR 237
Query: 2815 FGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALS 2873
F T++++ GG++ + G P V+W+ +T + G L L+
Sbjct: 238 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT-----PEDDMPIGRNVLELN 292
Query: 2874 DVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAV 2914
DV +S YTC A S G ++ A ITV G P V
Sbjct: 293 DV--RQSANYTCVAMSTLGVIEAIAQITVKPLPKPPGTPVV 331
Score = 64.1 bits (149), Expect = 8e-09
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 44/312 (14%)
Query: 3063 LAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID-DEGR 3121
++G A+ C G P P +VW K G +V + + +G L I+ + DE
Sbjct: 36 VSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI 95
Query: 3122 YSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQA 3181
Y C A+N G+ S RL V+ + + + D PQ + V+
Sbjct: 96 YECVASNNVGEISVSTRLTVLREDQIPRGFPTI----------DMGPQLKV------VER 139
Query: 3182 TYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHT-----------LEIAPT 3230
T + C G+P P+++W+KD V D N + +Q + L+I +
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPV--DTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 3231 NLDDGGVYEVTARNNSGA-VSCHCGLVVD--KGIRAYVAPEFCCGLEPL-YKLHEGDELR 3286
D G YE A N++G S L V + +R V P F + P +++ G +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRR-VPPRF--SIPPTNHEIMPGGSVN 254
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
I+ V P V W L P M + R+ L R + YTC A +
Sbjct: 255 ITCVAVGSPMPYVKWMLGAEDLTPEDD--MPIGRN-----VLELNDVRQSANYTCVAMST 307
Query: 3347 VGRASTSGKVEV 3358
+G ++ V
Sbjct: 308 LGVIEAIAQITV 319
Score = 58.8 bits (136), Expect = 3e-07
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 32/270 (11%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK-RRNKYQDEQ 3221
+ + PP+FT D+ + CQ G P PK+ W K G++V + ++ D
Sbjct: 19 DAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGS 78
Query: 3222 FHTLEIAPTNLD-DGGVYEVTARNNSGAVSCHCGLVV---DKGIRAYVAPEFCCGLEPLY 3277
L I P D +YE A NN G +S L V D+ R + P G P
Sbjct: 79 GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGF--PTIDMG--PQL 134
Query: 3278 KLHEGDE-LRISAVVEAYPSVGVTWYRDGVRLRPSRR--AIMTLDRDG------QIELAL 3328
K+ E + P +TW++D + + S I L + + L +
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQI 194
Query: 3329 AAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIR 3388
D G Y C A+N G S + + R+P P F
Sbjct: 195 EQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVP-------------PRFSI 240
Query: 3389 KPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
P + E G +V I C VG P P V W+
Sbjct: 241 PPTNHEIMPGGSVNITCVAVGSPMPYVKWM 270
Score = 53.2 bits (122), Expect = 2e-05
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 25/165 (15%)
Query: 3053 VDILPGQLKILAG-ETANLTCSVKGKPVPGVVWMKNGHEVE--EEAGRM----TSQFNGF 3105
+D+ P QLK++ TA + C+ G P P + W K+ V+ GR+ + G
Sbjct: 128 IDMGP-QLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT 186
Query: 3106 DC--CLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVE 3163
L I+ D+G+Y C ATN+ G T + A A L EV
Sbjct: 187 PIRGALQIEQSEESDQGKYECVATNSAG--------------TRYSAPANLYVRELREVR 232
Query: 3164 GDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEV 3208
PP+F++ + + V +TC +GSP P V W E++
Sbjct: 233 R-VPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDL 276
Score = 50.8 bits (116), Expect = 8e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 3295 PSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT-RDAGVYTCTASNEVGRASTS 3353
P + W + G ++ R ++ D L + + T RD +Y C ASN VG S S
Sbjct: 51 PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVS 110
Query: 3354 GKVEVIGTDQTSEPR-IPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPK 3412
++ V+ DQ PR P + + P + + + R T + C G+P
Sbjct: 111 TRLTVLREDQI--PRGFPTIDMGPQLKV------VERTR--------TATMLCAASGNPD 154
Query: 3413 PDVYWLRDFLKV 3424
P++ W +DFL V
Sbjct: 155 PEITWFKDFLPV 166
Score = 36.3 bits (80), Expect = 1.9
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P F I P +I+ G + N+TC G P+P V WM ++ E + L
Sbjct: 236 PRF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVL 289
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
+ D+ Y+C A +T G A++ V
Sbjct: 290 ELNDVR--QSANYTCVAMSTLGVIEAIAQITV 319
Score = 34.3 bits (75), Expect = 7.9
Identities = 33/106 (31%), Positives = 42/106 (39%), Gaps = 7/106 (6%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P FS T+ + G V +TC + S P V W +L L + G LE
Sbjct: 236 PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW----MLGAEDLTPEDDMPIGRNVLE- 290
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRS 2699
LN V SA Y+C + G I A + V P P P T S
Sbjct: 291 LNDV-RQSANYTCVAMSTLGVIEAIAQITVKP-LPKPPGTPVVTES 334
>Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C gene
protein.
Length = 1274
Score = 70.1 bits (164), Expect = 1e-10
Identities = 37/90 (41%), Positives = 46/90 (51%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L +R V A Y L C V GSP PK+SW+K+G ++ D R + + TLEI
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
DGG+Y A N G C C L V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 62.5 bits (145), Expect = 3e-08
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P+FT+ + + +A +L C +RG P PKI+WFK+ + D R++ F GV L
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLE 1239
Query: 2754 IDNPTPEDSGTYTCKAEN 2771
I P P D G Y C+A N
Sbjct: 1240 IRKPCPFDGGIYVCRATN 1257
Score = 57.2 bits (132), Expect = 1e-06
Identities = 27/90 (30%), Positives = 43/90 (47%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L +R+ + G L C+V S P ++W++NG+ L ++R G++TLE+
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
P D Y C N G L+V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 55.2 bits (127), Expect = 4e-06
Identities = 37/95 (38%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFD 3106
+ P F L + ++AG TA L C+V+G P P + W KNG ++ E+A RM S+ G
Sbjct: 1179 EAPSFTQPLVNR-SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK-QGV- 1235
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I+ D G Y C ATN G+A RL V
Sbjct: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 46.8 bits (106), Expect = 0.001
Identities = 47/153 (30%), Positives = 58/153 (37%), Gaps = 14/153 (9%)
Query: 2951 PGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVEL--GITPL 3005
P EP V D + VSL W + + Y VE EG + WV G+T
Sbjct: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC---PEGCSEWVAALQGLTEH 926
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL-- 3063
S +L G FRV N G G T+ + V RP LP L+
Sbjct: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ--LPRHLRQTIQ 984
Query: 3064 --AGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
GE NL +GKP P V W K G + E
Sbjct: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE 1017
Score = 46.8 bits (106), Expect = 0.001
Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + V G T L +RG P ++ W + G + E R R+F +QG+
Sbjct: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR-FRMFSKQGVL 1236
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
TL + + G+Y CRA + G + V P
Sbjct: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
Score = 41.5 bits (93), Expect = 0.052
Identities = 65/258 (25%), Positives = 101/258 (39%), Gaps = 34/258 (13%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD---KRRNKYQDEQFH 3223
P T L D+ V V C+V +V W KDG E+ + K R K +D Q H
Sbjct: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFK-KDGQRH 510
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCGL--EPLYKLH 3280
L I L+D G Y + SG + +V +K + Y + + G + ++K
Sbjct: 511 HLIINEAMLEDAGHYALCT---SGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCE 567
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
DE +V W ++G L P R + + G++ +L + VT D Y
Sbjct: 568 VSDE-----------NVRGVWLKNGKELVPDSR--IKVSHIGRVHKLTIDDVTPADEADY 614
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
+ E + S K+ + PR P I D P R P + G+
Sbjct: 615 SFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPG-------RIPDTIVVVAGN 665
Query: 3400 TVIIECEVVGDPKPDVYW 3417
+ ++ + GDP P V W
Sbjct: 666 KLRLDVPISGDPAPTVIW 683
Score = 37.5 bits (83), Expect = 0.84
Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 13/120 (10%)
Query: 2822 YQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGL-YTLALSDVTETES 2880
YQV++G I L VE+ V+WL+ G+ + ++ + +F G TL +S + +
Sbjct: 373 YQVSKGHKIRLTVELADHDAEVKWLKNGQEI-QMSGSKYIFESIGAKRTLTISQCSLADD 431
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
Y C G + + V + P V++ RP +D L+ VG+ + E
Sbjct: 432 AAYQC----VVGGEKCSTELFVKE-------PPVLITRPLEDQLVMVGQRVEFECEVSEE 480
Score = 37.1 bits (82), Expect = 1.1
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ V P ++W+++G+ L R M + G + L + D G+Y C A+N
Sbjct: 1200 LCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNL 1258
Query: 3347 VGRASTSGKVEV 3358
G A ++EV
Sbjct: 1259 QGEARCECRLEV 1270
>X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding protein
C protein.
Length = 1274
Score = 70.1 bits (164), Expect = 1e-10
Identities = 37/90 (41%), Positives = 46/90 (51%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L +R V A Y L C V GSP PK+SW+K+G ++ D R + + TLEI
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
DGG+Y A N G C C L V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 62.5 bits (145), Expect = 3e-08
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P+FT+ + + +A +L C +RG P PKI+WFK+ + D R++ F GV L
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLE 1239
Query: 2754 IDNPTPEDSGTYTCKAEN 2771
I P P D G Y C+A N
Sbjct: 1240 IRKPCPFDGGIYVCRATN 1257
Score = 57.2 bits (132), Expect = 1e-06
Identities = 27/90 (30%), Positives = 43/90 (47%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L +R+ + G L C+V S P ++W++NG+ L ++R G++TLE+
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
P D Y C N G L+V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 55.2 bits (127), Expect = 4e-06
Identities = 37/95 (38%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFD 3106
+ P F L + ++AG TA L C+V+G P P + W KNG ++ E+A RM S+ G
Sbjct: 1179 EAPSFTQPLVNR-SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK-QGV- 1235
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I+ D G Y C ATN G+A RL V
Sbjct: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 46.8 bits (106), Expect = 0.001
Identities = 47/153 (30%), Positives = 58/153 (37%), Gaps = 14/153 (9%)
Query: 2951 PGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVEL--GITPL 3005
P EP V D + VSL W + + Y VE EG + WV G+T
Sbjct: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC---PEGCSEWVAALQGLTEH 926
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL-- 3063
S +L G FRV N G G T+ + V RP LP L+
Sbjct: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ--LPRHLRQTIQ 984
Query: 3064 --AGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
GE NL +GKP P V W K G + E
Sbjct: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE 1017
Score = 46.8 bits (106), Expect = 0.001
Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + V G T L +RG P ++ W + G + E R R+F +QG+
Sbjct: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR-FRMFSKQGVL 1236
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
TL + + G+Y CRA + G + V P
Sbjct: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
Score = 42.3 bits (95), Expect = 0.030
Identities = 65/258 (25%), Positives = 101/258 (39%), Gaps = 34/258 (13%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD---KRRNKYQDEQFH 3223
P T L D+ V V C+V +V W KDG E+ + K R K +D Q H
Sbjct: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFK-KDGQRH 510
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCGL--EPLYKLH 3280
L I L+D G Y + SG + +V +K + Y + + G + ++K
Sbjct: 511 HLIINEAMLEDAGHYALCT---SGGQALRELIVQEKKLEVYQSIADLMVGAKDQAVFKCE 567
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
DE +V W ++G L P R + + G++ +L + VT D Y
Sbjct: 568 VSDE-----------NVRGVWLKNGKELVPDSR--IKVSHIGRVHKLTIDDVTPADEADY 614
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
+ E + S K+ + PR P I D P R P + G+
Sbjct: 615 SFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPG-------RIPDTIVVVAGN 665
Query: 3400 TVIIECEVVGDPKPDVYW 3417
+ ++ + GDP P V W
Sbjct: 666 KLRLDVPISGDPAPTVIW 683
Score = 37.5 bits (83), Expect = 0.84
Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 13/120 (10%)
Query: 2822 YQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGL-YTLALSDVTETES 2880
YQV++G I L VE+ V+WL+ G+ + ++ + +F G TL +S + +
Sbjct: 373 YQVSKGHKIRLTVELADHDAEVKWLKNGQEI-QMSGSKYIFESIGAKRTLTISQCSLADD 431
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
Y C G + + V + P V++ RP +D L+ VG+ + E
Sbjct: 432 AAYQC----VVGGEKCSTELFVKE-------PPVLITRPLEDQLVMVGQRVEFECEVSEE 480
Score = 37.1 bits (82), Expect = 1.1
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ V P ++W+++G+ L R M + G + L + D G+Y C A+N
Sbjct: 1200 LCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNL 1258
Query: 3347 VGRASTSGKVEV 3358
G A ++EV
Sbjct: 1259 QGEARCECRLEV 1270
>U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding
protein-C protein.
Length = 1274
Score = 70.1 bits (164), Expect = 1e-10
Identities = 37/90 (41%), Positives = 46/90 (51%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L +R V A Y L C V GSP PK+SW+K+G ++ D R + + TLEI
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
DGG+Y A N G C C L V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 62.5 bits (145), Expect = 3e-08
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P+FT+ + + +A +L C +RG P PKI+WFK+ + D R++ F GV L
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLE 1239
Query: 2754 IDNPTPEDSGTYTCKAEN 2771
I P P D G Y C+A N
Sbjct: 1240 IRKPCPFDGGIYVCRATN 1257
Score = 57.2 bits (132), Expect = 1e-06
Identities = 27/90 (30%), Positives = 43/90 (47%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L +R+ + G L C+V S P ++W++NG+ L ++R G++TLE+
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
P D Y C N G L+V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 55.2 bits (127), Expect = 4e-06
Identities = 37/95 (38%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFD 3106
+ P F L + ++AG TA L C+V+G P P + W KNG ++ E+A RM S+ G
Sbjct: 1179 EAPSFTQPLVNR-SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK-QGV- 1235
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I+ D G Y C ATN G+A RL V
Sbjct: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 46.8 bits (106), Expect = 0.001
Identities = 47/153 (30%), Positives = 58/153 (37%), Gaps = 14/153 (9%)
Query: 2951 PGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVEL--GITPL 3005
P EP V D + VSL W + + Y VE EG + WV G+T
Sbjct: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC---PEGCSEWVAALQGLTEH 926
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL-- 3063
S +L G FRV N G G T+ + V RP LP L+
Sbjct: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ--LPRHLRQTIQ 984
Query: 3064 --AGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
GE NL +GKP P V W K G + E
Sbjct: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE 1017
Score = 46.8 bits (106), Expect = 0.001
Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + V G T L +RG P ++ W + G + E R R+F +QG+
Sbjct: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR-FRMFSKQGVL 1236
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
TL + + G+Y CRA + G + V P
Sbjct: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
Score = 41.5 bits (93), Expect = 0.052
Identities = 65/258 (25%), Positives = 101/258 (39%), Gaps = 34/258 (13%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD---KRRNKYQDEQFH 3223
P T L D+ V V C+V +V W KDG E+ + K R K +D Q H
Sbjct: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFK-KDGQRH 510
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCGL--EPLYKLH 3280
L I L+D G Y + SG + +V +K + Y + + G + ++K
Sbjct: 511 HLIINEAMLEDAGHYALCT---SGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCE 567
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
DE +V W ++G L P R + + G++ +L + VT D Y
Sbjct: 568 VSDE-----------NVRGVWLKNGKELVPDSR--IKVSHIGRVHKLTIDDVTPADEADY 614
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
+ E + S K+ + PR P I D P R P + G+
Sbjct: 615 SFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPG-------RIPDTIVVVAGN 665
Query: 3400 TVIIECEVVGDPKPDVYW 3417
+ ++ + GDP P V W
Sbjct: 666 KLRLDVPISGDPAPTVIW 683
Score = 37.5 bits (83), Expect = 0.84
Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 13/120 (10%)
Query: 2822 YQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQGL-YTLALSDVTETES 2880
YQV++G I L VE+ V+WL+ G+ + ++ + +F G TL +S + +
Sbjct: 373 YQVSKGHKIRLTVELADHDAEVKWLKNGQEI-QMSGSKYIFESIGAKRTLTISQCSLADD 431
Query: 2881 GLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGE 2940
Y C G + + V + P V++ RP +D L+ VG+ + E
Sbjct: 432 AAYQC----VVGGEKCSTELFVKE-------PPVLITRPLEDQLVMVGQRVEFECEVSEE 480
Score = 37.1 bits (82), Expect = 1.1
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ V P ++W+++G+ L R M + G + L + D G+Y C A+N
Sbjct: 1200 LCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNL 1258
Query: 3347 VGRASTSGKVEV 3358
G A ++EV
Sbjct: 1259 QGEARCECRLEV 1270
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 70.1 bits (164), Expect = 1e-10
Identities = 86/337 (25%), Positives = 137/337 (40%), Gaps = 52/337 (15%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVPS- 2659
D +V GS V L CS S P + W ++G L+ R++L+ DG +L + N V S
Sbjct: 61 DTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDG--SLFISNVVHSK 118
Query: 2660 ----DSAEYSC--TVENENGAISTSANLKV--YPSFEASPIPPTFTRSIRDTFHLAENEL 2711
D Y C TVE+ IS +A L V P F + P P + A N
Sbjct: 119 HNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSV---------YAGNNA 169
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+L C + +P + W ++ + + D R L G+ L I N T D G Y C E+
Sbjct: 170 ILNCEVNADLVPFVRWEQNRQPLLLDDR--VIKLPSGM--LVISNATEGDGGLYRCVVES 225
Query: 2772 S---VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
++D++ E +V P+ +Q R G
Sbjct: 226 GGPPKYSDEV---------ELKVLPDPEVISDLVFLKQPSPLVR------------VIGQ 264
Query: 2829 TIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
+ L G PT ++W++ ++ V + G +L +SDVTE ++G Y C A
Sbjct: 265 DVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG--SLEISDVTEDDAGTYFCIA 322
Query: 2888 WSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDIL 2924
+ + ++ A +TV + +P I DI+
Sbjct: 323 DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV 359
Score = 69.3 bits (162), Expect = 2e-10
Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 14/173 (8%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
V G V L C PT+ W +N LD + R L+ G +LE+ + D+ Y
Sbjct: 261 VIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYF 319
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C +N N I A L V P F + + + ++V EC + G+P P +
Sbjct: 320 CIADNGNETIEAQAELTVQAQ-------PEFLKQPTNIYAHESMDIVFECEVTGKPTPTV 372
Query: 2726 TWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
W K+ D IPSD ++ L + D G Y C AEN V Q
Sbjct: 373 KWVKNGDMVIPSD-----YFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420
Score = 65.3 bits (152), Expect = 4e-09
Identities = 94/391 (24%), Positives = 146/391 (37%), Gaps = 53/391 (13%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG---HE 3090
S S G + P + + P + G + L CS +P P + W K+G +
Sbjct: 36 SGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNL 95
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V ++ ++ + F + N DEG Y C AT L + RT
Sbjct: 96 VSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVAT--------VESLGTIISRT---- 143
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
AKL V G P+FT + V A L C+V P V W ++ + ++
Sbjct: 144 -AKLI------VAG--LPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLL 194
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYE-VTARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
D R K L I+ DGG+Y V S L V F
Sbjct: 195 DDRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVF 251
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
PL ++ G ++ + V P+ + W ++ L + L G +E ++
Sbjct: 252 LKQPSPLVRV-IGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLE--IS 308
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
VT DAG Y C A N G + + E+ T Q +P F+++
Sbjct: 309 DVTEDDAGTYFCIADN--GNETIEAQAEL--TVQA------------------QPEFLKQ 346
Query: 3390 PRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P + A E ++ ECEV G P P V W+++
Sbjct: 347 PTNIYAHESMDIVFECEVTGKPTPTVKWVKN 377
Score = 60.1 bits (139), Expect = 1e-07
Identities = 51/211 (24%), Positives = 81/211 (38%), Gaps = 28/211 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + G+ L C G P P + WMKN ++ E+ G L I D+
Sbjct: 255 PSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTE 312
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD G Y C A N + T+ E AE+ P+F + +
Sbjct: 313 DDAGTYFCIADNGN--------------ETI---------EAQAELTVQAQPEFLKQPTN 349
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+ + C+V G P P V W K+G+ V+ + ++ + H L++ D G
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI---PSDYFKIVKEHNLQVLGLVKSDEG 406
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAP 3267
Y+ A N+ G L++ + A P
Sbjct: 407 FYQCIAENDVGNAQAGAQLIILEHAPATTGP 437
Score = 57.6 bits (133), Expect = 7e-07
Identities = 81/326 (24%), Positives = 122/326 (37%), Gaps = 39/326 (11%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
S+T+ I GL P F P + AG A L C V VP V W +N + +
Sbjct: 141 SRTAKLIVAGL----PRFTS-QPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLD 195
Query: 3095 AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA-TNTHGKASTYARLAVVTDRTVWEADAK 3153
R+ +G L I + D G Y C + K S L V+ D V
Sbjct: 196 -DRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVF 251
Query: 3154 LKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR 3213
LK+ P +R+ + V L C G P P + W K+ EE + +
Sbjct: 252 LKQ-----------PSPLVRVIGQDVV------LPCVASGLPTPTIKWMKN-EEALDTES 293
Query: 3214 RNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
+ +LEI+ DD G Y A N + + L V PEF
Sbjct: 294 SERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQ------AQPEFLKQP 347
Query: 3274 EPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
+Y HE ++ V P+ V W ++G + PS + + + Q+ +
Sbjct: 348 TNIYA-HESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQV----LGLVK 402
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVI 3359
D G Y C A N+VG A ++ ++
Sbjct: 403 SDEGFYQCIAENDVGNAQAGAQLIIL 428
Score = 44.0 bits (99), Expect = 0.010
Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 18/166 (10%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F T+ A E + C V PTV W +NG ++ Y K + + L+
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPS-DYFKIVKEH--NLQ 396
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP-PTFTRSIRDTFHLAENEL 2711
VL V SD Y C EN+ G A L + A+ P P+ R + L
Sbjct: 397 VLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDV--VASLVSTRF 454
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDN 2756
+ K+TW D Y FY +G+ R ++N
Sbjct: 455 I-----------KLTWRTPASDPHGDNLTYSVFYTKEGIARERVEN 489
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chicken)
protein.
Length = 1461
Score = 70.1 bits (164), Expect = 1e-10
Identities = 86/337 (25%), Positives = 137/337 (40%), Gaps = 52/337 (15%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVPS- 2659
D +V GS V L CS S P + W ++G L+ R++L+ DG +L + N V S
Sbjct: 61 DTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDG--SLFISNVVHSK 118
Query: 2660 ----DSAEYSC--TVENENGAISTSANLKV--YPSFEASPIPPTFTRSIRDTFHLAENEL 2711
D Y C TVE+ IS +A L V P F + P P + A N
Sbjct: 119 HNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSV---------YAGNNA 169
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+L C + +P + W ++ + + D R L G+ L I N T D G Y C E+
Sbjct: 170 ILNCEVNADLVPFVRWEQNRQPLLLDDR--VIKLPSGM--LVISNATEGDGGLYRCVVES 225
Query: 2772 S---VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
++D++ E +V P+ +Q R G
Sbjct: 226 GGPPKYSDEV---------ELKVLPDPEVISDLVFLKQPSPLVR------------VIGQ 264
Query: 2829 TIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
+ L G PT ++W++ ++ V + G +L +SDVTE ++G Y C A
Sbjct: 265 DVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG--SLEISDVTEDDAGTYFCIA 322
Query: 2888 WSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDIL 2924
+ + ++ A +TV + +P I DI+
Sbjct: 323 DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV 359
Score = 69.3 bits (162), Expect = 2e-10
Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 14/173 (8%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
V G V L C PT+ W +N LD + R L+ G +LE+ + D+ Y
Sbjct: 261 VIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYF 319
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C +N N I A L V P F + + + ++V EC + G+P P +
Sbjct: 320 CIADNGNETIEAQAELTVQAQ-------PEFLKQPTNIYAHESMDIVFECEVTGKPTPTV 372
Query: 2726 TWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
W K+ D IPSD ++ L + D G Y C AEN V Q
Sbjct: 373 KWVKNGDMVIPSD-----YFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420
Score = 65.3 bits (152), Expect = 4e-09
Identities = 94/391 (24%), Positives = 146/391 (37%), Gaps = 53/391 (13%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG---HE 3090
S S G + P + + P + G + L CS +P P + W K+G +
Sbjct: 36 SGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNL 95
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V ++ ++ + F + N DEG Y C AT L + RT
Sbjct: 96 VSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVAT--------VESLGTIISRT---- 143
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
AKL V G P+FT + V A L C+V P V W ++ + ++
Sbjct: 144 -AKLI------VAG--LPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLL 194
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYE-VTARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
D R K L I+ DGG+Y V S L V F
Sbjct: 195 DDRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVF 251
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
PL ++ G ++ + V P+ + W ++ L + L G +E ++
Sbjct: 252 LKQPSPLVRV-IGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLE--IS 308
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
VT DAG Y C A N G + + E+ T Q +P F+++
Sbjct: 309 DVTEDDAGTYFCIADN--GNETIEAQAEL--TVQA------------------QPEFLKQ 346
Query: 3390 PRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P + A E ++ ECEV G P P V W+++
Sbjct: 347 PTNIYAHESMDIVFECEVTGKPTPTVKWVKN 377
Score = 60.1 bits (139), Expect = 1e-07
Identities = 51/211 (24%), Positives = 81/211 (38%), Gaps = 28/211 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + G+ L C G P P + WMKN ++ E+ G L I D+
Sbjct: 255 PSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTE 312
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD G Y C A N + T+ E AE+ P+F + +
Sbjct: 313 DDAGTYFCIADNGN--------------ETI---------EAQAELTVQAQPEFLKQPTN 349
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+ + C+V G P P V W K+G+ V+ + ++ + H L++ D G
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI---PSDYFKIVKEHNLQVLGLVKSDEG 406
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAP 3267
Y+ A N+ G L++ + A P
Sbjct: 407 FYQCIAENDVGNAQAGAQLIILEHAPATTGP 437
Score = 57.6 bits (133), Expect = 7e-07
Identities = 81/326 (24%), Positives = 122/326 (37%), Gaps = 39/326 (11%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
S+T+ I GL P F P + AG A L C V VP V W +N + +
Sbjct: 141 SRTAKLIVAGL----PRFTS-QPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLD 195
Query: 3095 AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA-TNTHGKASTYARLAVVTDRTVWEADAK 3153
R+ +G L I + D G Y C + K S L V+ D V
Sbjct: 196 -DRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVF 251
Query: 3154 LKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR 3213
LK+ P +R+ + V L C G P P + W K+ EE + +
Sbjct: 252 LKQ-----------PSPLVRVIGQDVV------LPCVASGLPTPTIKWMKN-EEALDTES 293
Query: 3214 RNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
+ +LEI+ DD G Y A N + + L V PEF
Sbjct: 294 SERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQ------AQPEFLKQP 347
Query: 3274 EPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
+Y HE ++ V P+ V W ++G + PS + + + Q+ +
Sbjct: 348 TNIYA-HESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQV----LGLVK 402
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVI 3359
D G Y C A N+VG A ++ ++
Sbjct: 403 SDEGFYQCIAENDVGNAQAGAQLIIL 428
Score = 44.0 bits (99), Expect = 0.010
Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 18/166 (10%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F T+ A E + C V PTV W +NG ++ Y K + + L+
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPS-DYFKIVKEH--NLQ 396
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP-PTFTRSIRDTFHLAENEL 2711
VL V SD Y C EN+ G A L + A+ P P+ R + L
Sbjct: 397 VLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDV--VASLVSTRF 454
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDN 2756
+ K+TW D Y FY +G+ R ++N
Sbjct: 455 I-----------KLTWRTPASDPHGDNLTYSVFYTKEGIARERVEN 489
>BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1287
Score = 70.1 bits (164), Expect = 1e-10
Identities = 81/313 (25%), Positives = 132/313 (42%), Gaps = 54/313 (17%)
Query: 3109 LTIKDINIDDEGRYSCEATN--THG-KASTYARLAVVTDRTVWEADAKLKRERSAEVEGD 3165
L I +++++D+G Y C A N TH K R +V+ R S +V
Sbjct: 176 LQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVS------------RPSSDDVHIL 223
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RNKYQDEQFHT 3224
+P + V + PV L C V G P P+V W KDG+++ + R Y T
Sbjct: 224 HPTHS----QALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPESNWRRLY--SHLAT 277
Query: 3225 LEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDE 3284
+ P D G Y A N SG V + +V+ A ++ GL+ + G
Sbjct: 278 DSVDPA---DSGNYSCMAGNKSGDVK-YVTYMVNVLEHASISK----GLQDQI-VSLGAT 328
Query: 3285 LRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
+ + V P+ TW+ + + PS R + +G L ++ VT D G+Y C A
Sbjct: 329 VHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTA--GNG---LKISGVTVEDVGMYQCVAD 383
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
N +G ++G++E+ ++ PV+I+ P S++ +GD V +
Sbjct: 384 NGIGFMHSTGRLEI-----ENDGGFKPVIIT-------------APVSAKVADGDFVTLS 425
Query: 3405 CEVVGDPKPDVYW 3417
C G P P + W
Sbjct: 426 CNASGLPVPVIRW 438
Score = 60.9 bits (141), Expect = 8e-08
Identities = 71/302 (23%), Positives = 121/302 (40%), Gaps = 27/302 (8%)
Query: 2609 SRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTV 2668
S V L C V P V W ++G + + +R+ L L T V P+DS YSC
Sbjct: 237 SPVTLECVVSGVPAPQVYWLKDGQDIAPESNWRR-LYSHLATDSV---DPADSGNYSCMA 292
Query: 2669 ENENGAISTSANLKVYPSFEASPIP-PTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
N++G + Y ++ + + + ++ ++D + C + G P P TW
Sbjct: 293 GNKSGDVK-------YVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTW 345
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGR 2787
F + + I R+ +G L I T ED G Y C A+N + T +
Sbjct: 346 FHNAQPIHPSARH--LTAGNG---LKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIE-N 399
Query: 2788 ESQVSPNVVTAE-KTRIAR---QSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRV 2843
+ P ++TA ++A +L + + + G ++ +R
Sbjct: 400 DGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRK 459
Query: 2844 EWLR--EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAIT 2901
L EG ++ VY V + G +L + VT+ +G Y C A + HG A++
Sbjct: 460 SQLSRPEGLNLEPVY---FVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLM 516
Query: 2902 VV 2903
VV
Sbjct: 517 VV 518
Score = 56.4 bits (130), Expect = 2e-06
Identities = 72/324 (22%), Positives = 115/324 (35%), Gaps = 60/324 (18%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L +L+ L C V G P P V W+K+G ++ E S + L ++ D
Sbjct: 231 LAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPE-----SNWRRLYSHLATDSVDPADS 285
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G YSC A N G + V + + L+D+ V
Sbjct: 286 GNYSCMAGNKSGDVKYVTYMVNVLEHA----------------------SISKGLQDQIV 323
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
V TC V G+P P +W+ + + ++ R+ + L+I+ ++D G+Y+
Sbjct: 324 SLGATVHFTCDVHGNPAPNCTWFHNAQP-IHPSARHLTAG---NGLKISGVTVEDVGMYQ 379
Query: 3240 VTARNNSGAVSCHCGLVV--DKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV 3297
A N G + L + D G + + K+ +GD + +S P
Sbjct: 380 CVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSA-----KVADGDFVTLSCNASGLPVP 434
Query: 3298 GVTWY------------------RDGVRLRPS----RRAIMTLDRDGQIELALAAVTTRD 3335
+ WY R RP L + G L + AVT
Sbjct: 435 VIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEH 494
Query: 3336 AGVYTCTASNEVGRASTSGKVEVI 3359
AG Y C A+NE G + V+
Sbjct: 495 AGKYICEAANEHGTTQAEASLMVV 518
Score = 55.6 bits (128), Expect = 3e-06
Identities = 50/188 (26%), Positives = 80/188 (42%), Gaps = 18/188 (9%)
Query: 2604 TAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSA 2662
TA E S + C V S+ Y+ G L++ + L G L++LN D
Sbjct: 130 TAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSG--NLQILNVSLEDKG 187
Query: 2663 EYSCTVEN------ENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECR 2716
Y C N + I + S + + PT ++++ L+ + + LEC
Sbjct: 188 SYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAV---LSRSPVTLECV 244
Query: 2717 IRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN-SVWT 2775
+ G P P++ W KD + I + ++ Y LA D+ P DSG Y+C A N S
Sbjct: 245 VSGVPAPQVYWLKDGQDIAPESNWRRLY-----SHLATDSVDPADSGNYSCMAGNKSGDV 299
Query: 2776 DQITHFVN 2783
+T+ VN
Sbjct: 300 KYVTYMVN 307
Score = 50.8 bits (116), Expect = 8e-05
Identities = 84/361 (23%), Positives = 140/361 (38%), Gaps = 45/361 (12%)
Query: 2587 SRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD 2646
S +S P F++ G V L CS ++W NG LD L++ K +
Sbjct: 22 SVSSDLAPYFTSEPLSAVQKLGGPVVLHCSA-QPVTTRISWLHNGKTLDGNLEHIK-IHQ 79
Query: 2647 GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHL 2706
G +T+ LN+ S Y C N GAI + P+ + + F S +
Sbjct: 80 GTLTILSLNS--SLLGYYQCLANNSIGAIVSG------PATVSVAVLGDFGSSTKHVITA 131
Query: 2707 AENEL-VLECRI-RGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
E + CR+ P ++ + K + YL L I N + ED G+
Sbjct: 132 EEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTEN---YLILPSGNLQILNVSLEDKGS 188
Query: 2765 YTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Y C A N V T Q+ V GR+ VS R + + P L V
Sbjct: 189 YKCAAYNPV-THQLK--VEPIGRKLLVS---------RPSSDDVHILHPTHSQALA---V 233
Query: 2825 ARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
+ L+ + G P +V WL++G+ + R++ LA V +SG Y
Sbjct: 234 LSRSPVTLECVVSGVPAPQVYWLKDGQDIAPESNWRRLYSH-----LATDSVDPADSGNY 288
Query: 2884 TCRAWSAHGNVD-MNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPK 2942
+C A + G+V + + V++ + + + +D ++S+G ++ + G P
Sbjct: 289 SCMAGNKSGDVKYVTYMVNVLEHAS--------ISKGLQDQIVSLGATVHFTCDVHGNPA 340
Query: 2943 P 2943
P
Sbjct: 341 P 341
Score = 43.6 bits (98), Expect = 0.013
Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 2600 LTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
L D+ G+ V TC V + P TW+ N + ++ L G L++
Sbjct: 318 LQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARH---LTAG-NGLKISGVTVE 373
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIR 2718
D Y C +N G + ++ L++ P+ T S + +A+ + V L C
Sbjct: 374 DVGMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSAK----VADGDFVTLSCNAS 429
Query: 2719 GQPLPKITWFKDDKQIPS 2736
G P+P I W+ I S
Sbjct: 430 GLPVPVIRWYDSHGLITS 447
Score = 39.9 bits (89), Expect = 0.16
Identities = 69/265 (26%), Positives = 94/265 (35%), Gaps = 31/265 (11%)
Query: 3160 AEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQD 3219
+ V D P FT + PV L C ++SW +G+ + + K
Sbjct: 21 SSVSSDLAPYFTSEPLSAVQKLGGPVVLHCSA-QPVTTRISWLHNGKTLDGNLEHIKIHQ 79
Query: 3220 EQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
TL I N G Y+ A N+ GA+ V V +F + +
Sbjct: 80 G---TLTILSLNSSLLGYYQCLANNSIGAIVSGPATV-----SVAVLGDFGSSTKHVITA 131
Query: 3280 HEGDELRISA-VVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGV 3338
E I V E+ P V + G L S + L L + V+ D G
Sbjct: 132 EEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGN---LQILNVSLEDKGS 188
Query: 3339 YTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAR-- 3396
Y C A N V KVE IG +V P S + + I P S+A
Sbjct: 189 YKCAAYNPVTHQL---KVEPIGRKL--------LVSRP----SSDDVHILHPTHSQALAV 233
Query: 3397 -EGDTVIIECEVVGDPKPDVYWLRD 3420
V +EC V G P P VYWL+D
Sbjct: 234 LSRSPVTLECVVSGVPAPQVYWLKD 258
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 70.1 bits (164), Expect = 1e-10
Identities = 96/366 (26%), Positives = 140/366 (38%), Gaps = 65/366 (17%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID------D 3118
G+ L C V+G P + W KNG E+ E T NG L I+ ++ D
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPEST-HSTLLANG---SLMIRHFRLEPGGSPSD 111
Query: 3119 EGRYSCEATNTHGKA-STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
EG Y C A N G S AR+ T +D + + + EG
Sbjct: 112 EGDYECVAQNRFGLVVSRKARIQAAT-----MSDFHVHPQATVGEEGGV----------- 155
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
R CQ+ G P P ++W K+ V D +Y L+I +DGG+
Sbjct: 156 -------ARFQCQIHGLPKPLITWEKN--RVPIDTDNERYTLLPKGVLQITGLRAEDGGI 206
Query: 3238 YEVTARNNSGAVSCHCG--LVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
+ A N + H V G AY P G E L L + V P
Sbjct: 207 FHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENL-TLTVHQTAVLECVATGNP 265
Query: 3296 SVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
V+W R DG RP + + G L ++ VT + +GVY C A+ R
Sbjct: 266 RPIVSWSRLDG---RPI--GVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVR--- 317
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+T++ R+ VV +P F++ P+S G T + C+ G+P P
Sbjct: 318 --------RTAQGRL--VVQAP-------AEFVQHPQSISRPAGTTAMFTCQAQGEPPPH 360
Query: 3415 VYWLRD 3420
V WL++
Sbjct: 361 VTWLKN 366
Score = 60.5 bits (140), Expect = 1e-07
Identities = 97/356 (27%), Positives = 140/356 (39%), Gaps = 48/356 (13%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVL- 2654
F+ +D AV G + L C V + +TW +NGV L + L +G + +
Sbjct: 44 FAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPES-THSTLLANGSLMIRHFR 102
Query: 2655 ---NAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
PSD +Y C +N G +S A ++ + P ++ + +A
Sbjct: 103 LEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQA---TVGEEGGVAR-- 157
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+C+I G P P ITW K+ I +D RY L GV L I ED G + C A
Sbjct: 158 --FQCQIHGLPKPLITWEKNRVPIDTDNERYT--LLPKGV--LQITGLRAEDGGIFHCVA 211
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N + + +I+H G VS + A K E+ LT +Q T
Sbjct: 212 SN-IASIRISH-----GARLTVSGSGSGAYKEPAILVGPENL------TLTVHQ-----T 254
Query: 2830 IGLQVEIRGCPTR-VEWLR-EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
L+ G P V W R +GR + +V G L +SDVT SG+Y C A
Sbjct: 255 AVLECVATGNPRPIVSWSRLDGRPIG--VEGIQVL---GTGNLIISDVTVQHSGVYVCAA 309
Query: 2888 WSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V A +V + PA V P+ I G + + QGEP P
Sbjct: 310 NRPGTRVRRTAQGRLVVQA-----PAEFVQHPQ-SISRPAGTTAMFTCQAQGEPPP 359
Score = 58.4 bits (135), Expect = 4e-07
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EFV P + AG TA TC +G+P P V W+KNG +V G + + N + LT
Sbjct: 331 EFVQH-PQSISRPAGTTAMFTCQAQGEPPPHVTWLKNG-QVLGPGGHVRLKNN--NSTLT 386
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I I +DE Y C A N+ G + ARL V+
Sbjct: 387 ISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418
Score = 50.0 bits (114), Expect = 1e-04
Identities = 51/217 (23%), Positives = 80/217 (36%), Gaps = 29/217 (13%)
Query: 3042 GVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTS 3100
G G + + + P L + +TA L C G P P V W + +G + E ++
Sbjct: 229 GSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLG 288
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA 3160
N L I D+ + G Y C A N G +++R
Sbjct: 289 TGN-----LIISDVTVQHSGVYVC-AANRPG--------------------TRVRRTAQG 322
Query: 3161 EVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
+ P +F + A TCQ G PPP V+W K+G+ V +
Sbjct: 323 RLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ--VLGPGGHVRLKN 380
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
TL I+ +D +Y+ A N++G+ L V
Sbjct: 381 NNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417
Score = 48.4 bits (110), Expect = 5e-04
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ TC P VTW +NG +L R K + +T+ + P D A Y C
Sbjct: 344 GTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIG--PEDEAIYQCV 401
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSI 2700
EN G+ SA L V + E P PP R++
Sbjct: 402 AENSAGSSQASARLTVLWA-EGLPGPPRNVRAV 433
Score = 45.2 bits (102), Expect = 0.004
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 21/170 (12%)
Query: 2613 LTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD-----SAEYSCT 2667
L C + P V+W R LD R V+G+ L N + SD S Y C
Sbjct: 257 LECVATGNPRPIVSWSR----LDG----RPIGVEGIQVLGTGNLIISDVTVQHSGVYVCA 308
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
+ +A ++ P F + + A + C+ +G+P P +TW
Sbjct: 309 ANRPGTRVRRTAQGRLVVQ-----APAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTW 363
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K+ + + G + L + L I PED Y C AENS + Q
Sbjct: 364 LKNGQVLGPGGHVR---LKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQ 410
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 70.1 bits (164), Expect = 1e-10
Identities = 96/366 (26%), Positives = 140/366 (38%), Gaps = 65/366 (17%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINID------D 3118
G+ L C V+G P + W KNG E+ E T NG L I+ ++ D
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPEST-HSTLLANG---SLMIRHFRLEPGGSPSD 111
Query: 3119 EGRYSCEATNTHGKA-STYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDR 3177
EG Y C A N G S AR+ T +D + + + EG
Sbjct: 112 EGDYECVAQNRFGLVVSRKARIQAAT-----MSDFHVHPQATVGEEGGV----------- 155
Query: 3178 RVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGV 3237
R CQ+ G P P ++W K+ V D +Y L+I +DGG+
Sbjct: 156 -------ARFQCQIHGLPKPLITWEKN--RVPIDTDNERYTLLPKGVLQITGLRAEDGGI 206
Query: 3238 YEVTARNNSGAVSCHCG--LVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYP 3295
+ A N + H V G AY P G E L L + V P
Sbjct: 207 FHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENL-TLTVHQTAVLECVATGNP 265
Query: 3296 SVGVTWYR-DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
V+W R DG RP + + G L ++ VT + +GVY C A+ R
Sbjct: 266 RPIVSWSRLDG---RPI--GVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVR--- 317
Query: 3355 KVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPD 3414
+T++ R+ VV +P F++ P+S G T + C+ G+P P
Sbjct: 318 --------RTAQGRL--VVQAP-------AEFVQHPQSISRPAGTTAMFTCQAQGEPPPH 360
Query: 3415 VYWLRD 3420
V WL++
Sbjct: 361 VTWLKN 366
Score = 60.5 bits (140), Expect = 1e-07
Identities = 97/356 (27%), Positives = 140/356 (39%), Gaps = 48/356 (13%)
Query: 2596 FSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVL- 2654
F+ +D AV G + L C V + +TW +NGV L + L +G + +
Sbjct: 44 FAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPES-THSTLLANGSLMIRHFR 102
Query: 2655 ---NAVPSDSAEYSCTVENENG-AISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE 2710
PSD +Y C +N G +S A ++ + P ++ + +A
Sbjct: 103 LEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQA---TVGEEGGVAR-- 157
Query: 2711 LVLECRIRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDNPTPEDSGTYTCKA 2769
+C+I G P P ITW K+ I +D RY L GV L I ED G + C A
Sbjct: 158 --FQCQIHGLPKPLITWEKNRVPIDTDNERYT--LLPKGV--LQITGLRAEDGGIFHCVA 211
Query: 2770 ENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGT 2829
N + + +I+H G VS + A K E+ LT +Q T
Sbjct: 212 SN-IASIRISH-----GARLTVSGSGSGAYKEPAILVGPENL------TLTVHQ-----T 254
Query: 2830 IGLQVEIRGCPTR-VEWLR-EGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
L+ G P V W R +GR + +V G L +SDVT SG+Y C A
Sbjct: 255 AVLECVATGNPRPIVSWSRLDGRPIG--VEGIQVL---GTGNLIISDVTVQHSGVYVCAA 309
Query: 2888 WSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKP 2943
V A +V + PA V P+ I G + + QGEP P
Sbjct: 310 NRPGTRVRRTAQGRLVVQA-----PAEFVQHPQ-SISRPAGTTAMFTCQAQGEPPP 359
Score = 58.4 bits (135), Expect = 4e-07
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 3051 EFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLT 3110
EFV P + AG TA TC +G+P P V W+KNG +V G + + N + LT
Sbjct: 331 EFVQH-PQSISRPAGTTAMFTCQAQGEPPPHVTWLKNG-QVLGPGGHVRLKNN--NSTLT 386
Query: 3111 IKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
I I +DE Y C A N+ G + ARL V+
Sbjct: 387 ISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418
Score = 50.0 bits (114), Expect = 1e-04
Identities = 51/217 (23%), Positives = 80/217 (36%), Gaps = 29/217 (13%)
Query: 3042 GVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMK-NGHEVEEEAGRMTS 3100
G G + + + P L + +TA L C G P P V W + +G + E ++
Sbjct: 229 GSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLG 288
Query: 3101 QFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSA 3160
N L I D+ + G Y C A N G +++R
Sbjct: 289 TGN-----LIISDVTVQHSGVYVC-AANRPG--------------------TRVRRTAQG 322
Query: 3161 EVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDE 3220
+ P +F + A TCQ G PPP V+W K+G+ V +
Sbjct: 323 RLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ--VLGPGGHVRLKN 380
Query: 3221 QFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
TL I+ +D +Y+ A N++G+ L V
Sbjct: 381 NNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417
Score = 48.4 bits (110), Expect = 5e-04
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCT 2667
G+ TC P VTW +NG +L R K + +T+ + P D A Y C
Sbjct: 344 GTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIG--PEDEAIYQCV 401
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSI 2700
EN G+ SA L V + E P PP R++
Sbjct: 402 AENSAGSSQASARLTVLWA-EGLPGPPRNVRAV 433
Score = 45.2 bits (102), Expect = 0.004
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 21/170 (12%)
Query: 2613 LTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSD-----SAEYSCT 2667
L C + P V+W R LD R V+G+ L N + SD S Y C
Sbjct: 257 LECVATGNPRPIVSWSR----LDG----RPIGVEGIQVLGTGNLIISDVTVQHSGVYVCA 308
Query: 2668 VENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITW 2727
+ +A ++ P F + + A + C+ +G+P P +TW
Sbjct: 309 ANRPGTRVRRTAQGRLVVQ-----APAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTW 363
Query: 2728 FKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
K+ + + G + L + L I PED Y C AENS + Q
Sbjct: 364 LKNGQVLGPGGHVR---LKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQ 410
>AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein C,
cardiac protein.
Length = 1273
Score = 70.1 bits (164), Expect = 1e-10
Identities = 37/90 (41%), Positives = 46/90 (51%)
Query: 3168 PQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEI 3227
P FT L +R V A Y L C V GSP PK+SW+K+G ++ D R + + TLEI
Sbjct: 1180 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1239
Query: 3228 APTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
DGG+Y A N G C C L V
Sbjct: 1240 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1269
Score = 62.5 bits (145), Expect = 3e-08
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 2694 PTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLA 2753
P+FT+ + + +A +L C +RG P PKI+WFK+ + D R++ F GV L
Sbjct: 1180 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLE 1238
Query: 2754 IDNPTPEDSGTYTCKAEN 2771
I P P D G Y C+A N
Sbjct: 1239 IRKPCPFDGGIYVCRATN 1256
Score = 57.2 bits (132), Expect = 1e-06
Identities = 27/90 (30%), Positives = 43/90 (47%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
P F+ L +R+ + G L C+V S P ++W++NG+ L ++R G++TLE+
Sbjct: 1180 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1239
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKV 2683
P D Y C N G L+V
Sbjct: 1240 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1269
Score = 55.2 bits (127), Expect = 4e-06
Identities = 37/95 (38%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 3048 DRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAG-RMTSQFNGFD 3106
+ P F L + ++AG TA L C+V+G P P + W KNG ++ E+A RM S+ G
Sbjct: 1178 EAPSFTQPLVNR-SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK-QGV- 1234
Query: 3107 CCLTIKDINIDDEGRYSCEATNTHGKASTYARLAV 3141
L I+ D G Y C ATN G+A RL V
Sbjct: 1235 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1269
Score = 48.4 bits (110), Expect = 5e-04
Identities = 43/194 (22%), Positives = 79/194 (40%), Gaps = 14/194 (7%)
Query: 2574 SEARSVISEKRTLSRNSTRKPVFSTFLTDRTAV-EGSRVKLTCSVISSSDPTVTWYRNGV 2632
++ R ++ + + R+ + F L V +G +++LT ++ D V W +NG
Sbjct: 343 TDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVE-LADHDAEVKWLKNGQ 401
Query: 2633 LLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPI 2692
+ +Y + + TL + +D A Y C V E ST F P
Sbjct: 402 EIQMSGRYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK--CSTEL-------FVKEP- 451
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGV-CR 2751
P TR + D + + EC + + ++ W KD ++ + ++ + DG
Sbjct: 452 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 510
Query: 2752 LAIDNPTPEDSGTY 2765
L I+ ED+G Y
Sbjct: 511 LIINEAMLEDAGHY 524
Score = 46.8 bits (106), Expect = 0.001
Identities = 47/153 (30%), Positives = 58/153 (37%), Gaps = 14/153 (9%)
Query: 2951 PGEP---CVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVEL--GITPL 3005
P EP V D + VSL W + + Y VE EG + WV G+T
Sbjct: 869 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC---PEGCSEWVAALQGLTEH 925
Query: 3006 NSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKIL-- 3063
S +L G FRV N G G T+ + V RP LP L+
Sbjct: 926 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ--LPRHLRQTIQ 983
Query: 3064 --AGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
GE NL +GKP P V W K G + E
Sbjct: 984 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE 1016
Score = 46.8 bits (106), Expect = 0.001
Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 2810 SRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLY 2868
S P F L + V G T L +RG P ++ W + G + E R R+F +QG+
Sbjct: 1177 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR-FRMFSKQGVL 1235
Query: 2869 TLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQP 2905
TL + + G+Y CRA + G + V P
Sbjct: 1236 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1272
Score = 41.5 bits (93), Expect = 0.052
Identities = 65/258 (25%), Positives = 101/258 (39%), Gaps = 34/258 (13%)
Query: 3167 PPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYD---KRRNKYQDEQFH 3223
P T L D+ V V C+V +V W KDG E+ + K R K +D Q H
Sbjct: 452 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFK-KDGQRH 509
Query: 3224 TLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVA-PEFCCGL--EPLYKLH 3280
L I L+D G Y + SG + +V +K + Y + + G + ++K
Sbjct: 510 HLIINEAMLEDAGHYALCT---SGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCE 566
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI-ELALAAVTTRDAGVY 3339
DE +V W ++G L P R + + G++ +L + VT D Y
Sbjct: 567 VSDE-----------NVRGVWLKNGKELVPDSR--IKVSHIGRVHKLTIDDVTPADEADY 613
Query: 3340 TCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGD 3399
+ E + S K+ + PR P I D P R P + G+
Sbjct: 614 SFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPG-------RIPDTIVVVAGN 664
Query: 3400 TVIIECEVVGDPKPDVYW 3417
+ ++ + GDP P V W
Sbjct: 665 KLRLDVPISGDPAPTVIW 682
Score = 37.1 bits (82), Expect = 1.1
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 3287 ISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNE 3346
+ V P ++W+++G+ L R M + G + L + D G+Y C A+N
Sbjct: 1199 LCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNL 1257
Query: 3347 VGRASTSGKVEV 3358
G A ++EV
Sbjct: 1258 QGEARCECRLEV 1269
Score = 36.7 bits (81), Expect = 1.5
Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 16/121 (13%)
Query: 2822 YQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQ--GLYTLALSDVTETE 2879
YQV++G I L VE+ V+WL+ G+ E+ + R E TL +S + +
Sbjct: 373 YQVSKGHKIRLTVELADHDAEVKWLKNGQ---EIQMSGRYIFESIGAKRTLTISQCSLAD 429
Query: 2880 SGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQG 2939
Y C G + + V + P V++ RP +D L+ VG+ +
Sbjct: 430 DAAYQC----VVGGEKCSTELFVKE-------PPVLITRPLEDQLVMVGQRVEFECEVSE 478
Query: 2940 E 2940
E
Sbjct: 479 E 479
>AC115538-1|AAY40987.1| 103|Homo sapiens unknown protein.
Length = 103
Score = 70.1 bits (164), Expect = 1e-10
Identities = 37/97 (38%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Query: 3163 EGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRR-NKYQDEQ 3221
E PP F +L++ V YPVRL C+V+G PPP++ W K+ E + + R + +QD
Sbjct: 2 EAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNH 61
Query: 3222 -FHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVV 3257
+ L I +D G Y V+A+N +G VSC L V
Sbjct: 62 GYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 98
Score = 46.8 bits (106), Expect = 0.001
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 2693 PPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIP-SDGRYQAFYLADGVCR 2751
PP F +++T + LECR+ G P P+I W K+++ + S R G
Sbjct: 6 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 65
Query: 2752 LAIDNPTPEDSGTYTCKAEN 2771
L I T ED+G YT A+N
Sbjct: 66 LLIQGATKEDAGWYTVSAKN 85
Score = 44.8 bits (101), Expect = 0.006
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
Query: 2588 RNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVD- 2646
+ + + PVF L + +G V+L C V+ P + W + L + D
Sbjct: 1 KEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDN 60
Query: 2647 -GLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPS 2686
G I L + A D+ Y+ + +NE G +S +A L VY S
Sbjct: 61 HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 101
Score = 44.0 bits (99), Expect = 0.010
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 2/97 (2%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTS-QFNGFDCC 3108
P F++ L + G L C V G P P + W K + R++ Q N C
Sbjct: 7 PVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 65
Query: 3109 LTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDR 3145
L I+ +D G Y+ A N G S ARL V R
Sbjct: 66 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISR 102
Score = 41.5 bits (93), Expect = 0.052
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 3281 EGDELRISAVVEAYPSVGVTWYRDGVRLRPSR-RAIMTLDRDGQIELALAAVTTRDAGVY 3339
+G +R+ V P + W ++ L S R M D G I L + T DAG Y
Sbjct: 20 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 79
Query: 3340 TCTASNEVGRASTSGKVEV 3358
T +A NE G S + +++V
Sbjct: 80 TVSAKNEAGIVSCTARLDV 98
Score = 38.3 bits (85), Expect = 0.48
Identities = 14/39 (35%), Positives = 25/39 (64%)
Query: 3382 KEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
K P+FI K +++ +G V +EC V+G P P ++W ++
Sbjct: 5 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKE 43
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 70.1 bits (164), Expect = 1e-10
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 29/367 (7%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLA 2746
E+ P F + ++D H+AE + L+L+C++ P I W + K + + ++
Sbjct: 170 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQE 227
Query: 2747 DGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQ 2806
+C ++I+ PED G Y C A+N + + V T ++ S N E
Sbjct: 228 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV--TVDDAPASENTKAPE------- 278
Query: 2807 SLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVEWLREGRSVTEVYRNARVFVEQG 2866
++SRRP + G V+ + P + + + +V G
Sbjct: 279 -MKSRRPK-----SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV--RAG 330
Query: 2867 LYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDILIS 2926
VT T+ TC W + V+ S+ K ++ R E +
Sbjct: 331 ESVELFGKVTGTQP--ITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 387
Query: 2927 VGEDINISFRTQGEPKPKAV--PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKV 2984
+ + + R Q + V P+ G PC D ++ ++L+W S + V +Y +
Sbjct: 388 LLVENKLGSR-QAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 446
Query: 2985 ESWLIGAEGGARWVELGITPLNSFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVG 3044
E W W EL SF+ +L EY FRV N YG E SQ S VG
Sbjct: 447 EIW---DSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 503
Query: 3045 LAGDRPE 3051
+ P+
Sbjct: 504 EKPEEPK 510
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 881 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 940
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 941 GNCSLIISDVCGDDDAKYTCKAVNSL 966
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 896 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 955
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 956 AKYTCKAVNSLGEATCTAELIVET 979
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 882 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 940
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 941 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 977
Score = 53.2 bits (122), Expect = 2e-05
Identities = 62/275 (22%), Positives = 104/275 (37%), Gaps = 29/275 (10%)
Query: 3012 NLKQGEEYHFRVTPRNRYGW--GESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETAN 3069
NLK + + +N G + T + G P F L + + G+
Sbjct: 136 NLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLL 194
Query: 3070 LTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNT 3129
L C V P ++W NG ++ + SQ G C ++I+ +D G Y C A N
Sbjct: 195 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ-EGSLCSVSIEKALPEDRGLYKCVAKND 253
Query: 3130 HGKASTYARLAV----VTDRTV------------------WEADAKLKRERSAEV--EGD 3165
G+A ++ V ++ T E+DA +K++ + + +
Sbjct: 254 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 313
Query: 3166 YPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PPQ D++V+A V L +V G+ P +W K +++ + E L
Sbjct: 314 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 373
Query: 3226 EIAPTNLDDGGVYEVTARNNSGAVSCHCGL-VVDK 3259
I + G Y + N G+ L VVDK
Sbjct: 374 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 408
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 876 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 935
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 936 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 978
Score = 48.4 bits (110), Expect = 5e-04
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 2581 SEKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKY 2640
+EKR+ S+ + P F L D EG ++ L C V S T+ W NG L
Sbjct: 165 NEKRSESQGTA--PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 222
Query: 2641 RKKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV--YPSFEASPIPPTFTR 2698
L ++ + A+P D Y C +N+ G S + V P+ E + P +R
Sbjct: 223 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 282
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 886 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 945
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 946 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 977
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 886 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 945
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 946 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 986
Score = 42.3 bits (95), Expect = 0.030
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 3266 APEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQI- 3324
AP F L+ ++ + EG +L + V + P + W +G L+ ++ I L ++G +
Sbjct: 175 APAFKQKLQDVH-VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--LSQEGSLC 231
Query: 3325 ELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIP 3370
+++ D G+Y C A N+ G+A S +V V + + P
Sbjct: 232 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 277
Score = 39.1 bits (87), Expect = 0.28
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 2805 RQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFV 2863
R + P F L D VA G + LQ ++ P + W G+++ + + +
Sbjct: 168 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 226
Query: 2864 EQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV--VQPSDLDGKPAVIVGRPEK 2921
E L ++++ + GLY C A + G + + +TV S+ P + RP+
Sbjct: 227 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 286
Query: 2922 DILISVGEDINISFRTQGEPK--PK-AVPERI 2950
+ +G + + + + + PK PK A+P +I
Sbjct: 287 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 318
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 878 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 928
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 347 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 406
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 407 GNCSLIISDVCGDDDAKYTCKAVNSL 432
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 362 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 421
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 422 AKYTCKAVNSLGEATCTAELIVET 445
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 348 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 406
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 407 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 443
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 342 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 401
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 402 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 444
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 352 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 411
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 412 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 443
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 352 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 411
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 412 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 452
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 344 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 394
>BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein.
Length = 166
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 55 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 114
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 115 GNCSLIISDVCGDDDAKYTCKAVNSL 140
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 70 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 129
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 130 AKYTCKAVNSLGEATCTAELIVET 153
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 56 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 114
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 115 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 151
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 50 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 109
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 110 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 152
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 60 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 119
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 120 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 151
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 60 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 119
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 120 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 160
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 52 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 102
>BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein.
Length = 167
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 56 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 115
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 116 GNCSLIISDVCGDDDAKYTCKAVNSL 141
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 71 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 130
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 131 AKYTCKAVNSLGEATCTAELIVET 154
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 57 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 115
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 116 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 152
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 51 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 110
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 111 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 153
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 61 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 120
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 121 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 152
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 61 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 120
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 121 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 161
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 53 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 103
>BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein.
Length = 227
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 116 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 175
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 176 GNCSLIISDVCGDDDAKYTCKAVNSL 201
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 131 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 190
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 191 AKYTCKAVNSLGEATCTAELIVET 214
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 117 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 175
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 176 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 212
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 111 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 170
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 171 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 213
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 121 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 180
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 181 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 212
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 121 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 180
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 181 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 221
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 113 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 163
>BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSL 127
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 117 AKYTCKAVNSLGEATCTAELIVET 140
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 43 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 39 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 89
>BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSL 128
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 118 AKYTCKAVNSLGEATCTAELIVET 141
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 44 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 40 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 90
>BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSL 128
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 118 AKYTCKAVNSLGEATCTAELIVET 141
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 44 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 40 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 90
>BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSL 127
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 117 AKYTCKAVNSLGEATCTAELIVET 140
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 43 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 39 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 89
>BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein.
Length = 236
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 115 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 174
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 175 GNCSLIISDVCGDDDAKYTCKAVNSL 200
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 130 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 189
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 190 AKYTCKAVNSLGEATCTAELIVET 213
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 116 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 174
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 175 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 211
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 110 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 169
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 170 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 212
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 120 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 179
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 180 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 211
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 120 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 179
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 180 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 220
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 112 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 162
>AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein
isoform 2 protein.
Length = 154
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSL 128
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 118 AKYTCKAVNSLGEATCTAELIVET 141
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 44 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 40 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 90
>AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein
isoform 1 protein.
Length = 153
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSL 127
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 117 AKYTCKAVNSLGEATCTAELIVET 140
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 43 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 39 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 89
>AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein
protein.
Length = 154
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSL 128
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 118 AKYTCKAVNSLGEATCTAELIVET 141
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 44 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 40 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 90
>AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein
protein.
Length = 153
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSL 127
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 117 AKYTCKAVNSLGEATCTAELIVET 140
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 43 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 39 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 89
>AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle
myosin light chain kinase protein.
Length = 300
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 189 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 248
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 249 GNCSLIISDVCGDDDAKYTCKAVNSL 274
Score = 61.7 bits (143), Expect = 5e-08
Identities = 28/84 (33%), Positives = 44/84 (52%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 204 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 263
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A L V T
Sbjct: 264 AKYTCKAVNSLGEATCTAELIVET 287
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 190 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 248
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
G L ++ V D YTC A N +G A+ + ++ V
Sbjct: 249 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 285
Score = 50.0 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 184 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 243
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C L+V+
Sbjct: 244 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 286
Score = 48.0 bits (109), Expect = 6e-04
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 194 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 253
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+ + D A+Y+C N G + +A L V
Sbjct: 254 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 285
Score = 47.6 bits (108), Expect = 8e-04
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 194 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 253
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A + V + +G+
Sbjct: 254 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 294
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 186 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 236
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 47/86 (54%)
Query: 2688 EASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLAD 2747
E + P F+++IRD + + +C+I G P P++ WFKDD+ I +Q Y D
Sbjct: 449 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 508
Query: 2748 GVCRLAIDNPTPEDSGTYTCKAENSV 2773
G C L I + +D YTCKA NS+
Sbjct: 509 GNCSLIISDVCGDDDAKYTCKAVNSL 534
Score = 58.8 bits (136), Expect = 3e-07
Identities = 27/84 (32%), Positives = 43/84 (51%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L+++ G A C ++G P P VVW K+ + E +C L I D+ DD+
Sbjct: 464 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 523
Query: 3120 GRYSCEATNTHGKASTYARLAVVT 3143
+Y+C+A N+ G+A+ A V T
Sbjct: 524 AKYTCKAVNSLGEATCTAEHIVET 547
Score = 56.0 bits (129), Expect = 2e-06
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 3262 RAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRD 3321
+ +V P F + L ++ EG R +E YP V W++D +R SR + D D
Sbjct: 450 KPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 508
Query: 3322 GQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSE 3366
G L ++ V D YTC A N +G A+ + + ++ T + E
Sbjct: 509 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE-HIVETMEEGE 552
Score = 52.4 bits (120), Expect = 3e-05
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 3/105 (2%)
Query: 2947 PERIPGEPCVVDGGNNWVSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLN 3006
P+ G PC D ++ ++L+W S + V +Y +E W W EL
Sbjct: 51 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIW---DSANKTWKELATCRST 107
Query: 3007 SFDAFNLKQGEEYHFRVTPRNRYGWGESSQTSSSIGVGLAGDRPE 3051
SF+ +L EY FRV N YG E SQ S VG + P+
Sbjct: 108 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 152
Score = 47.2 bits (107), Expect = 0.001
Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 1/103 (0%)
Query: 3157 ERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR-RN 3215
E AE + P F+ +RD V R C++ G P P+V W+KD + + + +
Sbjct: 444 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 503
Query: 3216 KYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVD 3258
Y ++ +L I+ DD Y A N+ G +C +V+
Sbjct: 504 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 546
Score = 46.0 bits (104), Expect = 0.002
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL-VDGLITL 2651
KP FS + D VEGS + C + DP V W+++ + ++ DG +L
Sbjct: 454 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 513
Query: 2652 EVLNAVPSDSAEYSCTVENENGAISTSA 2679
+ + D A+Y+C N G + +A
Sbjct: 514 IISDVCGDDDAKYTCKAVNSLGEATCTA 541
Score = 45.6 bits (103), Expect = 0.003
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 2812 RPHFGNVLTDYQVARGGTIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTL 2870
+P+F + D +V G +I G P V W ++ +S+ E + E G +L
Sbjct: 454 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 513
Query: 2871 ALSDVTETESGLYTCRAWSAHGNVDMNAAITVVQPSDLDGK 2911
+SDV + YTC+A ++ G A V + +G+
Sbjct: 514 IISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGE 554
Score = 36.7 bits (81), Expect = 1.5
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 3374 ISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWLRDFLKVR 3425
++ + P+ K P F + R E EG +C++ G P P+V W +D +R
Sbjct: 446 VAEEKPHVK-PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 496
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 69.3 bits (162), Expect = 2e-10
Identities = 86/337 (25%), Positives = 137/337 (40%), Gaps = 52/337 (15%)
Query: 2602 DRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLV-DGLITLEVLNAVPS- 2659
D +V GS V L CS S P + W ++G L+ R++L+ DG +L + N V S
Sbjct: 61 DTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDG--SLFISNVVHSK 118
Query: 2660 ----DSAEYSC--TVENENGAISTSANLKV--YPSFEASPIPPTFTRSIRDTFHLAENEL 2711
D Y C TVE+ IS +A L V P F + P P + A N
Sbjct: 119 HNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSV---------YAGNGA 169
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+L C + +P + W ++ + + D R L G+ L I N T D G Y C E+
Sbjct: 170 ILNCEVNADLVPFVRWEQNRQPLLLDDR--VIKLPSGM--LVISNATEGDGGLYRCVVES 225
Query: 2772 S---VWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGG 2828
++D++ E +V P+ +Q R G
Sbjct: 226 GGPPKYSDEV---------ELKVLPDPEVISDLVFLKQPSPLVR------------VIGQ 264
Query: 2829 TIGLQVEIRGCPT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRA 2887
+ L G PT ++W++ ++ V + G +L +SDVTE ++G Y C A
Sbjct: 265 DVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG--SLEISDVTEDDAGTYFCIA 322
Query: 2888 WSAHGNVDMNAAITVVQPSDLDGKPAVIVGRPEKDIL 2924
+ + ++ A +TV + +P I DI+
Sbjct: 323 DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV 359
Score = 69.3 bits (162), Expect = 2e-10
Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 14/173 (8%)
Query: 2606 VEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAEYS 2665
V G V L C PT+ W +N LD + R L+ G +LE+ + D+ Y
Sbjct: 261 VIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYF 319
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLPKI 2725
C +N N I A L V P F + + + ++V EC + G+P P +
Sbjct: 320 CIADNGNETIEAQAELTVQAQ-------PEFLKQPTNIYAHESMDIVFECEVTGKPTPTV 372
Query: 2726 TWFKD-DKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQ 2777
W K+ D IPSD ++ L + D G Y C AEN V Q
Sbjct: 373 KWVKNGDMVIPSD-----YFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420
Score = 65.3 bits (152), Expect = 4e-09
Identities = 94/391 (24%), Positives = 146/391 (37%), Gaps = 53/391 (13%)
Query: 3034 SSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNG---HE 3090
S S G + P + + P + G + L CS +P P + W K+G +
Sbjct: 36 SGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNL 95
Query: 3091 VEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSCEATNTHGKASTYARLAVVTDRTVWEA 3150
V ++ ++ + F + N DEG Y C AT L + RT
Sbjct: 96 VSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVAT--------VESLGTIISRT---- 143
Query: 3151 DAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVY 3210
AKL V G P+FT + V A L C+V P V W ++ + ++
Sbjct: 144 -AKLI------VAG--LPRFTSQPEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPLLL 194
Query: 3211 DKRRNKYQDEQFHTLEIAPTNLDDGGVYE-VTARNNSGAVSCHCGLVVDKGIRAYVAPEF 3269
D R K L I+ DGG+Y V S L V F
Sbjct: 195 DDRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVF 251
Query: 3270 CCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALA 3329
PL ++ G ++ + V P+ + W ++ L + L G +E ++
Sbjct: 252 LKQPSPLVRV-IGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLE--IS 308
Query: 3330 AVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRK 3389
VT DAG Y C A N G + + E+ T Q +P F+++
Sbjct: 309 DVTEDDAGTYFCIADN--GNETIEAQAEL--TVQA------------------QPEFLKQ 346
Query: 3390 PRSSEAREGDTVIIECEVVGDPKPDVYWLRD 3420
P + A E ++ ECEV G P P V W+++
Sbjct: 347 PTNIYAHESMDIVFECEVTGKPTPTVKWVKN 377
Score = 60.1 bits (139), Expect = 1e-07
Identities = 51/211 (24%), Positives = 81/211 (38%), Gaps = 28/211 (13%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + G+ L C G P P + WMKN ++ E+ G L I D+
Sbjct: 255 PSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTE 312
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
DD G Y C A N + T+ E AE+ P+F + +
Sbjct: 313 DDAGTYFCIADNGN--------------ETI---------EAQAELTVQAQPEFLKQPTN 349
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+ + C+V G P P V W K+G+ V+ + ++ + H L++ D G
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI---PSDYFKIVKEHNLQVLGLVKSDEG 406
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAP 3267
Y+ A N+ G L++ + A P
Sbjct: 407 FYQCIAENDVGNAQAGAQLIILEHAPATTGP 437
Score = 56.8 bits (131), Expect = 1e-06
Identities = 81/326 (24%), Positives = 122/326 (37%), Gaps = 39/326 (11%)
Query: 3035 SQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEE 3094
S+T+ I GL P F P + AG A L C V VP V W +N + +
Sbjct: 141 SRTAKLIVAGL----PRFTS-QPEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPLLLD 195
Query: 3095 AGRMTSQFNGFDCCLTIKDINIDDEGRYSCEA-TNTHGKASTYARLAVVTDRTVWEADAK 3153
R+ +G L I + D G Y C + K S L V+ D V
Sbjct: 196 -DRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVF 251
Query: 3154 LKRERSAEVEGDYPPQFTMRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKR 3213
LK+ P +R+ + V L C G P P + W K+ EE + +
Sbjct: 252 LKQ-----------PSPLVRVIGQDVV------LPCVASGLPTPTIKWMKN-EEALDTES 293
Query: 3214 RNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGL 3273
+ +LEI+ DD G Y A N + + L V PEF
Sbjct: 294 SERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQ------AQPEFLKQP 347
Query: 3274 EPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVTT 3333
+Y HE ++ V P+ V W ++G + PS + + + Q+ +
Sbjct: 348 TNIYA-HESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQV----LGLVK 402
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVI 3359
D G Y C A N+VG A ++ ++
Sbjct: 403 SDEGFYQCIAENDVGNAQAGAQLIIL 428
Score = 44.0 bits (99), Expect = 0.010
Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 18/166 (10%)
Query: 2593 KPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLE 2652
+P F T+ A E + C V PTV W +NG ++ Y K + + L+
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPS-DYFKIVKEH--NLQ 396
Query: 2653 VLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIP-PTFTRSIRDTFHLAENEL 2711
VL V SD Y C EN+ G A L + A+ P P+ R + L
Sbjct: 397 VLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDV--VASLVSTRF 454
Query: 2712 VLECRIRGQPLPKITWFKDDKQIPSDG-RYQAFYLADGVCRLAIDN 2756
+ K+TW D Y FY +G+ R ++N
Sbjct: 455 I-----------KLTWRTPASDPHGDNLTYSVFYTKEGIARERVEN 489
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 69.3 bits (162), Expect = 2e-10
Identities = 73/305 (23%), Positives = 112/305 (36%), Gaps = 39/305 (12%)
Query: 3057 PGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINI 3116
P L + GE L C G P P + W+ NG +E + + +G + ++
Sbjct: 361 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQE 418
Query: 3117 DDEGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRD 3176
Y C A+N +G A + V+ AE P T+
Sbjct: 419 RSSAVYQCNASNEYGYLLANAFVNVL-----------------AEPPRILTPANTLY--- 458
Query: 3177 RRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGG 3236
+V A P L C GSP P + W+K + + Y + TLEI D G
Sbjct: 459 -QVIANRPALLDCAFFGSPLPTIEWFKGAKGSAL--HEDIYVLHENGTLEIPVAQKDSTG 515
Query: 3237 VYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPS 3296
Y ARN G L + PE+ + G + V+ +
Sbjct: 516 TYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAV-------VQRGSMVSFECKVKHDHT 568
Query: 3297 VGVT--WYRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSG 3354
+ +T W +D L R T+D+D L +A V+ D+G YTC A+ + S S
Sbjct: 569 LSLTVLWLKDNRELPSDER--FTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASA 623
Query: 3355 KVEVI 3359
+ V+
Sbjct: 624 VLSVV 628
Score = 68.1 bits (159), Expect = 5e-10
Identities = 79/323 (24%), Positives = 130/323 (40%), Gaps = 44/323 (13%)
Query: 2585 TLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKL 2644
T+S P + T + G L C + P ++W NGV ++ +
Sbjct: 346 TISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 405
Query: 2645 VDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTF 2704
+DG T+ N SA Y C NE G + +A + V PP +
Sbjct: 406 IDG-DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE------PPRILTPANTLY 458
Query: 2705 HLAENE-LVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSG 2763
+ N +L+C G PLP I WFK K ++ Y+ L I + +G
Sbjct: 459 QVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTG 515
Query: 2764 TYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQ 2823
TYTC A N + +++V + A T I +Q P +
Sbjct: 516 TYTCVARNKLGM-----------AKNEVHLEIKDA--TWIVKQ------PEYA------V 550
Query: 2824 VARGGTIGLQVEIRGCPT---RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETES 2880
V RG + + +++ T V WL++ R E+ + R V++ L ++DV++ +S
Sbjct: 551 VQRGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKD--HLVVADVSDDDS 605
Query: 2881 GLYTCRAWSAHGNVDMNAAITVV 2903
G YTC A + +V +A ++VV
Sbjct: 606 GTYTCVANTTLDSVSASAVLSVV 628
Score = 66.1 bits (154), Expect = 2e-09
Identities = 93/352 (26%), Positives = 141/352 (40%), Gaps = 42/352 (11%)
Query: 2611 VKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE-----YS 2665
+ + C P+ +W RNG D + G TL ++N + AE Y
Sbjct: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL-IINIMSEGKAETYEGVYQ 116
Query: 2666 CTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE-LVLECRIR-GQPLP 2723
CT NE GA + S N+ V PS P +T+ + L + LVL CR G P P
Sbjct: 117 CTARNERGA-AVSNNIVVRPSRS-----PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPP 170
Query: 2724 KITWFKDDKQ-IPSDGRYQAFYLADGVCRLAIDNPTPEDSGT-YTCKAE-NSVWTDQITH 2780
I W + Q +P R D L N PED+ Y C A N T Q
Sbjct: 171 IIFWMDNSFQRLPQSERVSQGLNGD----LYFSNVLPEDTREDYICYARFNHTQTIQQKQ 226
Query: 2781 FVNFTGRESQVSPNVVTAEKTRI---ARQSLESRRPHF----GNVLTDYQVARGGTIGLQ 2833
++ + + A + +S R P F GN ++ + RG + L+
Sbjct: 227 PISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNA-SNKEELRGNVLSLE 285
Query: 2834 VEIRGCPTRV-EWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHG 2892
G PT + W +E + +N V+ + TL + V+E +SG Y C A +A G
Sbjct: 286 CIAEGLPTPIIYWAKEDGMLP---KNRTVY-KNFEKTLQIIHVSEADSGNYQCIAKNALG 341
Query: 2893 NVDMNAAITVVQPSDLDGKPAVIVGRPEKDILISVGEDINISFRTQGEPKPK 2944
+ ++ V K A +++++S GED + R G PKP+
Sbjct: 342 AIHHTISVRV--------KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 385
Score = 54.4 bits (125), Expect = 7e-06
Identities = 84/375 (22%), Positives = 147/375 (39%), Gaps = 54/375 (14%)
Query: 3060 LKILAGETANLTCSVK-GKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDD 3118
+ + +G++ L C G P P + WM N + ++ R++ NG D + + D
Sbjct: 149 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG-DLYFS-NVLPEDT 206
Query: 3119 EGRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERS------AEVEGDYPPQFTM 3172
Y C A H + + V +V E + + S A+ + PP F
Sbjct: 207 REDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLT 266
Query: 3173 ---RLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAP 3229
++ + L C G P P + W K E+ + K R Y++ + TL+I
Sbjct: 267 PEGNASNKEELRGNVLSLECIAEGLPTPIIYWAK--EDGMLPKNRTVYKNFE-KTLQIIH 323
Query: 3230 TNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISA 3289
+ D G Y+ A+N GA+ H + +R AP + + L L G++ +
Sbjct: 324 VSEADSGNYQCIAKNALGAI--HHTI----SVRVKAAPYWITAPQNLV-LSPGEDGTLIC 376
Query: 3290 VVEAYPSVGVTWYRDGVRLR-----PSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTAS 3344
P ++W +GV + PSR+ +D D + + V R + VY C AS
Sbjct: 377 RANGNPKPRISWLTNGVPIEIAPDDPSRK----IDGD---TIIFSNVQERSSAVYQCNAS 429
Query: 3345 NEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIE 3404
NE G + V V+ PP +++P + + +P +++
Sbjct: 430 NEYGYLLANAFVNVLAE--------PPRILTP--ANTLYQVIANRP----------ALLD 469
Query: 3405 CEVVGDPKPDVYWLR 3419
C G P P + W +
Sbjct: 470 CAFFGSPLPTIEWFK 484
Score = 48.0 bits (109), Expect = 6e-04
Identities = 75/304 (24%), Positives = 120/304 (39%), Gaps = 50/304 (16%)
Query: 2592 RKPVFST---FLTDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDG 2647
R P F T +++ + G+ + L C P + W + +G+L N+ Y+
Sbjct: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-- 317
Query: 2648 LITLEVLNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLA 2707
TL++++ +DS Y C +N GAI + +++V +A+P T +++
Sbjct: 318 --TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV----KAAPYWITAPQNL--VLSPG 369
Query: 2708 ENELVLECRIRGQPLPKITWFKDDKQI---PSDGRYQAFYLADGVCRLAIDNPTPEDSGT 2764
E+ ++ CR G P P+I+W + I P D + DG + N S
Sbjct: 370 EDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRK----IDG-DTIIFSNVQERSSAV 423
Query: 2765 YTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQV 2824
Y C A N FVN V AE RI + N L YQV
Sbjct: 424 YQCNASNEYGYLLANAFVN------------VLAEPPRILTPA---------NTL--YQV 460
Query: 2825 ARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLY 2883
L G P +EW + G + ++ + V E G TL + + +G Y
Sbjct: 461 IANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTY 517
Query: 2884 TCRA 2887
TC A
Sbjct: 518 TCVA 521
Score = 44.8 bits (101), Expect = 0.006
Identities = 67/274 (24%), Positives = 105/274 (38%), Gaps = 31/274 (11%)
Query: 3167 PPQFTMRL-RDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTL 3225
PP T + +D + + + C+ G PPP SW ++G DK TL
Sbjct: 39 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 98
Query: 3226 EIAPTNLDDG------GVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKL 3279
I + +G GVY+ TARN GA + +VV E LEP+ L
Sbjct: 99 II--NIMSEGKAETYEGVYQCTARNERGAAVSN-NIVVRPSRSPLWTKE---KLEPI-TL 151
Query: 3280 HEGDELRISAVVEAYPSVG-----VTWYRDGV-RLRPSRRAIMTLDRDGQIELALAAVTT 3333
G L V+ P +G + W + RL S R L+ D L T
Sbjct: 152 QSGQSL----VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTR 207
Query: 3334 RDAGVYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISP--DVPYSKE--PMFIRK 3389
D Y + + V+VI D+ ++ + + S+E P F+
Sbjct: 208 EDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTP 267
Query: 3390 PRSSEARE---GDTVIIECEVVGDPKPDVYWLRD 3420
++ +E G+ + +EC G P P +YW ++
Sbjct: 268 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE 301
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion molecule
L1 protein.
Length = 1257
Score = 68.9 bits (161), Expect = 3e-10
Identities = 80/300 (26%), Positives = 122/300 (40%), Gaps = 38/300 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GETA L C V+G+P P V W NG VEE A ++ L + ++ D C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELA--KDQKYRIQRGALILSNVQPSDTMVTQC 404
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
EA N HG A + VV + AK+ + Q M ++ Y
Sbjct: 405 EARNRHGLLLANAYIYVV------QLPAKILTADN---------QTYMAVQG---STAY- 445
Query: 3185 VRLTCQVIGSPPPKVSWY-KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+ G+P P V W +DG V+ D+R Y + TL I +D G Y A
Sbjct: 446 --LLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAA 500
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV--GVTW 3301
N+ V+ L V + P + K +G + + PS+ +TW
Sbjct: 501 NDQNNVTIMANLKVKDATQITQGPR-----STIEK--KGSRVTFTCQASFDPSLQPSITW 553
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
DG L+ + DG+ L + ++ D G Y+C AS E+ + ++ V+G+
Sbjct: 554 RGDGRDLQELGDSDKYFIEDGR--LVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
Score = 62.1 bits (144), Expect = 3e-08
Identities = 72/299 (24%), Positives = 126/299 (42%), Gaps = 39/299 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK-KLVDGLITLEVLNAVPSDSAEYSC 2666
G +L C V P VTW NG+ ++ K +K ++ G + L N PSD+ C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILS--NVQPSDTMVTQC 404
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKI 2725
N +G + AN +Y +P + T+ + L C+ G P+P +
Sbjct: 405 EARNRHGLL--LANAYIY----VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 2726 TWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W +D + D R+ F A+G L I + D+G Y C A N + +T N
Sbjct: 459 QWLDEDGTTVLQDERF--FPYANGT--LGIRDLQANDTGRYFCLAAND--QNNVTIMANL 512
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+++ + T+ R ++E + G+ +T + LQ P+ +
Sbjct: 513 KVKDA--------TQITQGPRSTIEKK----GSRVT-FTCQASFDPSLQ------PS-IT 552
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +GR + E+ + + F+E G L + + ++ G Y+C A + V+ A + VV
Sbjct: 553 WRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVV 609
Score = 60.9 bits (141), Expect = 8e-08
Identities = 71/310 (22%), Positives = 123/310 (39%), Gaps = 41/310 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A++G + L C PT+ W R +G + +++ Y+ TL++L D E
Sbjct: 254 ALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNK----TLQLLKVGEEDDGE 309
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G SA Y + EA+P + + + L+C+++G+P P
Sbjct: 310 YRCLAENSLG----SARHAYYVTVEAAPY---WLHKPQSHLYGPGETARLDCQVQGRPQP 362
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW + + + Q + + G L + N P D+ C+A N ++
Sbjct: 363 EVTWRINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
Q+ ++TA+ Y +G T L + G P
Sbjct: 421 VV----QLPAKILTADN-------------------QTYMAVQGSTAYLLCKAFGAPVPS 457
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+WL E T V ++ R F TL + D+ ++G Y C A + NV + A + V
Sbjct: 458 VQWLDE--DGTTVLQDER-FFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
Query: 2903 VQPSDLDGKP 2912
+ + P
Sbjct: 515 KDATQITQGP 524
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 15/172 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWY-RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
AV+GS L C + P+V W +G + ++ +G + + L A +D+
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP-YANGTLGIRDLQA--NDTGR 494
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP-- 2721
Y C N+ ++ ANLKV +A+ I T+ R T + + C+ P
Sbjct: 495 YFCLAANDQNNVTIMANLKVK---DATQI----TQGPRSTIEKKGSRVTFTCQASFDPSL 547
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P ITW D + + G +++ DG RL I + D G Y+C A +
Sbjct: 548 QPSITWRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTEL 597
Score = 51.2 bits (117), Expect = 6e-05
Identities = 74/306 (24%), Positives = 121/306 (39%), Gaps = 40/306 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS-AEYS 2665
EG V L C+ S++P ++ N +L K R + L N + SD+ ++Y
Sbjct: 150 EGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG-NLYFANVLTSDNHSDYI 208
Query: 2666 CTVENENGAI---STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE---LVLECRIRG 2719
C +L+V + P + HL + LVLEC G
Sbjct: 209 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 268
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W + +P+D + Y L + ED G Y C AENS+ + +
Sbjct: 269 FPTPTIKWLRPSGPMPAD---RVTYQNHNK-TLQLLKVGEEDDGEYRCLAENSLGSARHA 324
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
++ VT E P++ + + G T L +++G
Sbjct: 325 YY--------------VTVEAA-----------PYWLHKPQSHLYGPGETARLDCQVQGR 359
Query: 2840 P-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P V W G V E+ ++ + +++G L LS+V +++ + C A + HG + NA
Sbjct: 360 PQPEVTWRINGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANA 417
Query: 2899 AITVVQ 2904
I VVQ
Sbjct: 418 YIYVVQ 423
Score = 46.8 bits (106), Expect = 0.001
Identities = 72/311 (23%), Positives = 114/311 (36%), Gaps = 39/311 (12%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L L G+ L C +G P P + W++ + A R+T Q + L + + +D+
Sbjct: 252 LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMP--ADRVTYQ--NHNKTLQLLKVGEEDD 307
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C A N+ G A +A V W L + +S Y P T
Sbjct: 308 GEYRCLAENSLGSAR-HAYYVTVEAAPYW-----LHKPQSHL----YGPGET-------- 349
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL CQV G P P+V+W +G V + KY+ ++ L ++ D V +
Sbjct: 350 -----ARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQ 403
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
ARN G + + + V + + Y +G + P V
Sbjct: 404 CEARNRHGLLLANAYIYV-----VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 3300 TWY-RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W DG + R + L + + D G Y C A+N+ + ++V
Sbjct: 459 QWLDEDGTTVLQDERFFPYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
Query: 3359 IGTDQ-TSEPR 3368
Q T PR
Sbjct: 515 KDATQITQGPR 525
Score = 43.2 bits (97), Expect = 0.017
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 32/235 (13%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
P+ L C G P P + W + + D R YQ+ TL++ +D G Y A
Sbjct: 259 PLVLECIAEGFPTPTIKWLRPSGPMPAD--RVTYQNHN-KTLQLLKVGEEDDGEYRCLAE 315
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+ G+ + V+ P+ LY G+ R+ V+ P VTW
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHKPQ-----SHLY--GPGETARLDCQVQGRPQPEVTWRI 368
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+G+ + + + G L L+ V D V C A N G + + V+
Sbjct: 369 NGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---- 422
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
++P +++ D ++ A +G T + C+ G P P V WL
Sbjct: 423 ----QLPAKILTAD------------NQTYMAVQGSTAYLLCKAFGAPVPSVQWL 461
Score = 37.1 bits (82), Expect = 1.1
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 10/122 (8%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA-FNLKQGEEYHFR 3022
V ++W ++ AP+ Y +E + +W LG P N L Y FR
Sbjct: 631 VRVSWSPAEDHN-APIEKYDIE-FEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFR 688
Query: 3023 VTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGV 3082
VT N+YG GE S S ++ A VD+ K ET N+ + KP+ +
Sbjct: 689 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDV-----KGEGNETTNMV--ITWKPLRWM 741
Query: 3083 VW 3084
W
Sbjct: 742 DW 743
Score = 35.5 bits (78), Expect = 3.4
Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 26/142 (18%)
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL---DRDGQIELA--LAAVTTRDAG 3337
D++ + P V W RDGV +P +T+ G + + R G
Sbjct: 51 DDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQG 110
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
+Y C ASN++G A S ++ ++ P+ P + P E E
Sbjct: 111 IYRCFASNKLGTA-MSHEIRLMA---EGAPKWPKETVKP----------------VEVEE 150
Query: 3398 GDTVIIECEVVGDPKP-DVYWL 3418
G++V++ C +P +YW+
Sbjct: 151 GESVVLPCNPPPSAEPLRIYWM 172
>X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion molecule
L1 protein.
Length = 1257
Score = 68.9 bits (161), Expect = 3e-10
Identities = 80/300 (26%), Positives = 122/300 (40%), Gaps = 38/300 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GETA L C V+G+P P V W NG VEE A ++ L + ++ D C
Sbjct: 347 GETARLDCQVEGRPQPEVTWRINGIPVEELA--KDQKYRIQRGALILSNVQPSDTMVTQC 404
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
EA N HG A + VV + AK+ + Q M ++ Y
Sbjct: 405 EARNRHGLLLANAYIYVV------QLPAKILTADN---------QTYMAVQG---STAY- 445
Query: 3185 VRLTCQVIGSPPPKVSWY-KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+ G+P P V W +DG V+ D+R Y + TL I +D G Y A
Sbjct: 446 --LLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAA 500
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV--GVTW 3301
N+ V+ L V + P + K +G + + PS+ +TW
Sbjct: 501 NDQNNVTIMANLKVKDATQITQGPR-----STIEK--KGSRVTFTCQASFDPSLQPSITW 553
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
DG L+ + DG+ L + ++ D G Y+C AS E+ + ++ V+G+
Sbjct: 554 RGDGRDLQELGDSDKYFIEDGR--LVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
Score = 62.1 bits (144), Expect = 3e-08
Identities = 72/299 (24%), Positives = 126/299 (42%), Gaps = 39/299 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK-KLVDGLITLEVLNAVPSDSAEYSC 2666
G +L C V P VTW NG+ ++ K +K ++ G + L N PSD+ C
Sbjct: 347 GETARLDCQVEGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILS--NVQPSDTMVTQC 404
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKI 2725
N +G + AN +Y +P + T+ + L C+ G P+P +
Sbjct: 405 EARNRHGLL--LANAYIY----VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 2726 TWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W +D + D R+ F A+G L I + D+G Y C A N + +T N
Sbjct: 459 QWLDEDGTTVLQDERF--FPYANGT--LGIRDLQANDTGRYFCLAAND--QNNVTIMANL 512
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+++ + T+ R ++E + G+ +T + LQ P+ +
Sbjct: 513 KVKDA--------TQITQGPRSTIEKK----GSRVT-FTCQASFDPSLQ------PS-IT 552
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +GR + E+ + + F+E G L + + ++ G Y+C A + V+ A + VV
Sbjct: 553 WRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVV 609
Score = 55.6 bits (128), Expect = 3e-06
Identities = 71/314 (22%), Positives = 122/314 (38%), Gaps = 41/314 (13%)
Query: 2601 TDRTAVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPS 2659
T A++G + L C PT+ R +G + +++ Y+ TL++L
Sbjct: 250 THLVALQGQPLVLECIAEGFPTPTIKSVRPSGPMPADRVTYQNHNK----TLQLLKVGEE 305
Query: 2660 DSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRG 2719
D EY C EN G SA Y + EA+P + + + L+C++ G
Sbjct: 306 DDGEYRCLAENSLG----SARHAYYVTVEAAPY---WLHKPQSHLYGPGETARLDCQVEG 358
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
+P P++TW + + + Q + + G L + N P D+ C+A N
Sbjct: 359 RPQPEVTWRINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLAN 416
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
++ Q+ ++TA+ Y +G T L + G
Sbjct: 417 AYIYVV----QLPAKILTADN-------------------QTYMAVQGSTAYLLCKAFGA 453
Query: 2840 PT-RVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P V+WL E T V ++ R F TL + D+ ++G Y C A + NV + A
Sbjct: 454 PVPSVQWLDE--DGTTVLQDER-FFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 510
Query: 2899 AITVVQPSDLDGKP 2912
+ V + + P
Sbjct: 511 NLKVKDATQITQGP 524
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 15/172 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWY-RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
AV+GS L C + P+V W +G + ++ +G + + L A +D+
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP-YANGTLGIRDLQA--NDTGR 494
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP-- 2721
Y C N+ ++ ANLKV +A+ I T+ R T + + C+ P
Sbjct: 495 YFCLAANDQNNVTIMANLKVK---DATQI----TQGPRSTIEKKGSRVTFTCQASFDPSL 547
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P ITW D + + G +++ DG RL I + D G Y+C A +
Sbjct: 548 QPSITWRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTEL 597
Score = 40.7 bits (91), Expect = 0.090
Identities = 71/311 (22%), Positives = 113/311 (36%), Gaps = 39/311 (12%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L L G+ L C +G P P + ++ + A R+T Q + L + + +D+
Sbjct: 252 LVALQGQPLVLECIAEGFPTPTIKSVRPSGPMP--ADRVTYQ--NHNKTLQLLKVGEEDD 307
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C A N+ G A +A V W L + +S Y P T
Sbjct: 308 GEYRCLAENSLGSAR-HAYYVTVEAAPYW-----LHKPQSHL----YGPGET-------- 349
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL CQV G P P+V+W +G V + KY+ ++ L ++ D V +
Sbjct: 350 -----ARLDCQVEGRPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQ 403
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
ARN G + + + V + + Y +G + P V
Sbjct: 404 CEARNRHGLLLANAYIYV-----VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 3300 TWY-RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W DG + R + L + + D G Y C A+N+ + ++V
Sbjct: 459 QWLDEDGTTVLQDERFFPYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
Query: 3359 IGTDQ-TSEPR 3368
Q T PR
Sbjct: 515 KDATQITQGPR 525
Score = 37.1 bits (82), Expect = 1.1
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 10/122 (8%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA-FNLKQGEEYHFR 3022
V ++W ++ AP+ Y +E + +W LG P N L Y FR
Sbjct: 631 VRVSWSPAEDHN-APIEKYDIE-FEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFR 688
Query: 3023 VTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGV 3082
VT N+YG GE S S ++ A VD+ K ET N+ + KP+ +
Sbjct: 689 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDV-----KGEGNETTNMV--ITWKPLRWM 741
Query: 3083 VW 3084
W
Sbjct: 742 DW 743
Score = 35.5 bits (78), Expect = 3.4
Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 26/142 (18%)
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL---DRDGQIELA--LAAVTTRDAG 3337
D++ + P V W RDGV +P +T+ G + + R G
Sbjct: 51 DDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQG 110
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
+Y C ASN++G A S ++ ++ P+ P + P E E
Sbjct: 111 IYRCFASNKLGTA-MSHEIRLMA---EGAPKWPKETVKP----------------VEVEE 150
Query: 3398 GDTVIIECEVVGDPKP-DVYWL 3418
G++V++ C +P +YW+
Sbjct: 151 GESVVLPCNPPPSAEPLRIYWM 172
Score = 35.5 bits (78), Expect = 3.4
Identities = 13/34 (38%), Positives = 22/34 (64%)
Query: 3384 PMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYW 3417
P ++ KP+S G+T ++C+V G P+P+V W
Sbjct: 333 PYWLHKPQSHLYGPGETARLDCQVEGRPQPEVTW 366
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 68.9 bits (161), Expect = 3e-10
Identities = 80/300 (26%), Positives = 122/300 (40%), Gaps = 38/300 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GETA L C V+G+P P V W NG VEE A ++ L + ++ D C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELA--KDQKYRIQRGALILSNVQPSDTMVTQC 404
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
EA N HG A + VV + AK+ + Q M ++ Y
Sbjct: 405 EARNRHGLLLANAYIYVV------QLPAKILTADN---------QTYMAVQG---STAY- 445
Query: 3185 VRLTCQVIGSPPPKVSWY-KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+ G+P P V W +DG V+ D+R Y + TL I +D G Y A
Sbjct: 446 --LLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAA 500
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV--GVTW 3301
N+ V+ L V + P + K +G + + PS+ +TW
Sbjct: 501 NDQNNVTIMANLKVKDATQITQGPR-----STIEK--KGSRVTFTCQASFDPSLQPSITW 553
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
DG L+ + DG+ L + ++ D G Y+C AS E+ + ++ V+G+
Sbjct: 554 RGDGRDLQELGDSDKYFIEDGR--LVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
Score = 62.1 bits (144), Expect = 3e-08
Identities = 72/299 (24%), Positives = 126/299 (42%), Gaps = 39/299 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK-KLVDGLITLEVLNAVPSDSAEYSC 2666
G +L C V P VTW NG+ ++ K +K ++ G + L N PSD+ C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILS--NVQPSDTMVTQC 404
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKI 2725
N +G + AN +Y +P + T+ + L C+ G P+P +
Sbjct: 405 EARNRHGLL--LANAYIY----VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 2726 TWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W +D + D R+ F A+G L I + D+G Y C A N + +T N
Sbjct: 459 QWLDEDGTTVLQDERF--FPYANGT--LGIRDLQANDTGRYFCLAAND--QNNVTIMANL 512
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+++ + T+ R ++E + G+ +T + LQ P+ +
Sbjct: 513 KVKDA--------TQITQGPRSTIEKK----GSRVT-FTCQASFDPSLQ------PS-IT 552
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +GR + E+ + + F+E G L + + ++ G Y+C A + V+ A + VV
Sbjct: 553 WRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVV 609
Score = 60.9 bits (141), Expect = 8e-08
Identities = 71/310 (22%), Positives = 123/310 (39%), Gaps = 41/310 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A++G + L C PT+ W R +G + +++ Y+ TL++L D E
Sbjct: 254 ALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNK----TLQLLKVGEEDDGE 309
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G SA Y + EA+P + + + L+C+++G+P P
Sbjct: 310 YRCLAENSLG----SARHAYYVTVEAAPY---WLHKPQSHLYGPGETARLDCQVQGRPQP 362
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW + + + Q + + G L + N P D+ C+A N ++
Sbjct: 363 EVTWRINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
Q+ ++TA+ Y +G T L + G P
Sbjct: 421 VV----QLPAKILTADN-------------------QTYMAVQGSTAYLLCKAFGAPVPS 457
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+WL E T V ++ R F TL + D+ ++G Y C A + NV + A + V
Sbjct: 458 VQWLDE--DGTTVLQDER-FFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
Query: 2903 VQPSDLDGKP 2912
+ + P
Sbjct: 515 KDATQITQGP 524
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 15/172 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWY-RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
AV+GS L C + P+V W +G + ++ +G + + L A +D+
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP-YANGTLGIRDLQA--NDTGR 494
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP-- 2721
Y C N+ ++ ANLKV +A+ I T+ R T + + C+ P
Sbjct: 495 YFCLAANDQNNVTIMANLKVK---DATQI----TQGPRSTIEKKGSRVTFTCQASFDPSL 547
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P ITW D + + G +++ DG RL I + D G Y+C A +
Sbjct: 548 QPSITWRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTEL 597
Score = 51.2 bits (117), Expect = 6e-05
Identities = 74/306 (24%), Positives = 121/306 (39%), Gaps = 40/306 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS-AEYS 2665
EG V L C+ S++P ++ N +L K R + L N + SD+ ++Y
Sbjct: 150 EGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG-NLYFANVLTSDNHSDYI 208
Query: 2666 CTVENENGAI---STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE---LVLECRIRG 2719
C +L+V + P + HL + LVLEC G
Sbjct: 209 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 268
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W + +P+D + Y L + ED G Y C AENS+ + +
Sbjct: 269 FPTPTIKWLRPSGPMPAD---RVTYQNHNK-TLQLLKVGEEDDGEYRCLAENSLGSARHA 324
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
++ VT E P++ + + G T L +++G
Sbjct: 325 YY--------------VTVEAA-----------PYWLHKPQSHLYGPGETARLDCQVQGR 359
Query: 2840 P-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P V W G V E+ ++ + +++G L LS+V +++ + C A + HG + NA
Sbjct: 360 PQPEVTWRINGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANA 417
Query: 2899 AITVVQ 2904
I VVQ
Sbjct: 418 YIYVVQ 423
Score = 46.8 bits (106), Expect = 0.001
Identities = 72/311 (23%), Positives = 114/311 (36%), Gaps = 39/311 (12%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L L G+ L C +G P P + W++ + A R+T Q + L + + +D+
Sbjct: 252 LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMP--ADRVTYQ--NHNKTLQLLKVGEEDD 307
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C A N+ G A +A V W L + +S Y P T
Sbjct: 308 GEYRCLAENSLGSAR-HAYYVTVEAAPYW-----LHKPQSHL----YGPGET-------- 349
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL CQV G P P+V+W +G V + KY+ ++ L ++ D V +
Sbjct: 350 -----ARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQ 403
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
ARN G + + + V + + Y +G + P V
Sbjct: 404 CEARNRHGLLLANAYIYV-----VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 3300 TWY-RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W DG + R + L + + D G Y C A+N+ + ++V
Sbjct: 459 QWLDEDGTTVLQDERFFPYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
Query: 3359 IGTDQ-TSEPR 3368
Q T PR
Sbjct: 515 KDATQITQGPR 525
Score = 43.2 bits (97), Expect = 0.017
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 32/235 (13%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
P+ L C G P P + W + + D R YQ+ TL++ +D G Y A
Sbjct: 259 PLVLECIAEGFPTPTIKWLRPSGPMPAD--RVTYQNHN-KTLQLLKVGEEDDGEYRCLAE 315
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+ G+ + V+ P+ LY G+ R+ V+ P VTW
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHKPQ-----SHLY--GPGETARLDCQVQGRPQPEVTWRI 368
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+G+ + + + G L L+ V D V C A N G + + V+
Sbjct: 369 NGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---- 422
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
++P +++ D ++ A +G T + C+ G P P V WL
Sbjct: 423 ----QLPAKILTAD------------NQTYMAVQGSTAYLLCKAFGAPVPSVQWL 461
Score = 37.1 bits (82), Expect = 1.1
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 10/122 (8%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA-FNLKQGEEYHFR 3022
V ++W ++ AP+ Y +E + +W LG P N L Y FR
Sbjct: 631 VRVSWSPAEDHN-APIEKYDIE-FEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFR 688
Query: 3023 VTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGV 3082
VT N+YG GE S S ++ A VD+ K ET N+ + KP+ +
Sbjct: 689 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDV-----KGEGNETTNMV--ITWKPLRWM 741
Query: 3083 VW 3084
W
Sbjct: 742 DW 743
Score = 35.5 bits (78), Expect = 3.4
Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 26/142 (18%)
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL---DRDGQIELA--LAAVTTRDAG 3337
D++ + P V W RDGV +P +T+ G + + R G
Sbjct: 51 DDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQG 110
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
+Y C ASN++G A S ++ ++ P+ P + P E E
Sbjct: 111 IYRCFASNKLGTA-MSHEIRLMA---EGAPKWPKETVKP----------------VEVEE 150
Query: 3398 GDTVIIECEVVGDPKP-DVYWL 3418
G++V++ C +P +YW+
Sbjct: 151 GESVVLPCNPPPSAEPLRIYWM 172
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 68.9 bits (161), Expect = 3e-10
Identities = 80/300 (26%), Positives = 122/300 (40%), Gaps = 38/300 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GETA L C V+G+P P V W NG VEE A ++ L + ++ D C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELA--KDQKYRIQRGALILSNVQPSDTMVTQC 404
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
EA N HG A + VV + AK+ + Q M ++ Y
Sbjct: 405 EARNRHGLLLANAYIYVV------QLPAKILTADN---------QTYMAVQG---STAY- 445
Query: 3185 VRLTCQVIGSPPPKVSWY-KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+ G+P P V W +DG V+ D+R Y + TL I +D G Y A
Sbjct: 446 --LLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAA 500
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV--GVTW 3301
N+ V+ L V + P + K +G + + PS+ +TW
Sbjct: 501 NDQNNVTIMANLKVKDATQITQGPR-----STIEK--KGSRVTFTCQASFDPSLQPSITW 553
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
DG L+ + DG+ L + ++ D G Y+C AS E+ + ++ V+G+
Sbjct: 554 RGDGRDLQELGDSDKYFIEDGR--LVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
Score = 62.1 bits (144), Expect = 3e-08
Identities = 72/299 (24%), Positives = 126/299 (42%), Gaps = 39/299 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK-KLVDGLITLEVLNAVPSDSAEYSC 2666
G +L C V P VTW NG+ ++ K +K ++ G + L N PSD+ C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILS--NVQPSDTMVTQC 404
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKI 2725
N +G + AN +Y +P + T+ + L C+ G P+P +
Sbjct: 405 EARNRHGLL--LANAYIY----VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 2726 TWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W +D + D R+ F A+G L I + D+G Y C A N + +T N
Sbjct: 459 QWLDEDGTTVLQDERF--FPYANGT--LGIRDLQANDTGRYFCLAAND--QNNVTIMANL 512
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+++ + T+ R ++E + G+ +T + LQ P+ +
Sbjct: 513 KVKDA--------TQITQGPRSTIEKK----GSRVT-FTCQASFDPSLQ------PS-IT 552
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +GR + E+ + + F+E G L + + ++ G Y+C A + V+ A + VV
Sbjct: 553 WRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVV 609
Score = 60.9 bits (141), Expect = 8e-08
Identities = 71/310 (22%), Positives = 123/310 (39%), Gaps = 41/310 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A++G + L C PT+ W R +G + +++ Y+ TL++L D E
Sbjct: 254 ALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNK----TLQLLKVGEEDDGE 309
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G SA Y + EA+P + + + L+C+++G+P P
Sbjct: 310 YRCLAENSLG----SARHAYYVTVEAAPY---WLHKPQSHLYGPGETARLDCQVQGRPQP 362
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW + + + Q + + G L + N P D+ C+A N ++
Sbjct: 363 EVTWRINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
Q+ ++TA+ Y +G T L + G P
Sbjct: 421 VV----QLPAKILTADN-------------------QTYMAVQGSTAYLLCKAFGAPVPS 457
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+WL E T V ++ R F TL + D+ ++G Y C A + NV + A + V
Sbjct: 458 VQWLDE--DGTTVLQDER-FFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
Query: 2903 VQPSDLDGKP 2912
+ + P
Sbjct: 515 KDATQITQGP 524
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 15/172 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWY-RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
AV+GS L C + P+V W +G + ++ +G + + L A +D+
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP-YANGTLGIRDLQA--NDTGR 494
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP-- 2721
Y C N+ ++ ANLKV +A+ I T+ R T + + C+ P
Sbjct: 495 YFCLAANDQNNVTIMANLKVK---DATQI----TQGPRSTIEKKGSRVTFTCQASFDPSL 547
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P ITW D + + G +++ DG RL I + D G Y+C A +
Sbjct: 548 QPSITWRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTEL 597
Score = 51.2 bits (117), Expect = 6e-05
Identities = 74/306 (24%), Positives = 121/306 (39%), Gaps = 40/306 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS-AEYS 2665
EG V L C+ S++P ++ N +L K R + L N + SD+ ++Y
Sbjct: 150 EGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG-NLYFANVLTSDNHSDYI 208
Query: 2666 CTVENENGAI---STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE---LVLECRIRG 2719
C +L+V + P + HL + LVLEC G
Sbjct: 209 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 268
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W + +P+D + Y L + ED G Y C AENS+ + +
Sbjct: 269 FPTPTIKWLRPSGPMPAD---RVTYQNHNK-TLQLLKVGEEDDGEYRCLAENSLGSARHA 324
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
++ VT E P++ + + G T L +++G
Sbjct: 325 YY--------------VTVEAA-----------PYWLHKPQSHLYGPGETARLDCQVQGR 359
Query: 2840 P-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P V W G V E+ ++ + +++G L LS+V +++ + C A + HG + NA
Sbjct: 360 PQPEVTWRINGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANA 417
Query: 2899 AITVVQ 2904
I VVQ
Sbjct: 418 YIYVVQ 423
Score = 46.8 bits (106), Expect = 0.001
Identities = 72/311 (23%), Positives = 114/311 (36%), Gaps = 39/311 (12%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L L G+ L C +G P P + W++ + A R+T Q + L + + +D+
Sbjct: 252 LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMP--ADRVTYQ--NHNKTLQLLKVGEEDD 307
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C A N+ G A +A V W L + +S Y P T
Sbjct: 308 GEYRCLAENSLGSAR-HAYYVTVEAAPYW-----LHKPQSHL----YGPGET-------- 349
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL CQV G P P+V+W +G V + KY+ ++ L ++ D V +
Sbjct: 350 -----ARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQ 403
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
ARN G + + + V + + Y +G + P V
Sbjct: 404 CEARNRHGLLLANAYIYV-----VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 458
Query: 3300 TWY-RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W DG + R + L + + D G Y C A+N+ + ++V
Sbjct: 459 QWLDEDGTTVLQDERFFPYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
Query: 3359 IGTDQ-TSEPR 3368
Q T PR
Sbjct: 515 KDATQITQGPR 525
Score = 43.2 bits (97), Expect = 0.017
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 32/235 (13%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
P+ L C G P P + W + + D R YQ+ TL++ +D G Y A
Sbjct: 259 PLVLECIAEGFPTPTIKWLRPSGPMPAD--RVTYQNHN-KTLQLLKVGEEDDGEYRCLAE 315
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+ G+ + V+ P+ LY G+ R+ V+ P VTW
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHKPQ-----SHLY--GPGETARLDCQVQGRPQPEVTWRI 368
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+G+ + + + G L L+ V D V C A N G + + V+
Sbjct: 369 NGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---- 422
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
++P +++ D ++ A +G T + C+ G P P V WL
Sbjct: 423 ----QLPAKILTAD------------NQTYMAVQGSTAYLLCKAFGAPVPSVQWL 461
Score = 37.1 bits (82), Expect = 1.1
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 10/122 (8%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA-FNLKQGEEYHFR 3022
V ++W ++ AP+ Y +E + +W LG P N L Y FR
Sbjct: 631 VRVSWSPAEDHN-APIEKYDIE-FEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFR 688
Query: 3023 VTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGV 3082
VT N+YG GE S S ++ A VD+ K ET N+ + KP+ +
Sbjct: 689 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDV-----KGEGNETTNMV--ITWKPLRWM 741
Query: 3083 VW 3084
W
Sbjct: 742 DW 743
Score = 35.5 bits (78), Expect = 3.4
Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 26/142 (18%)
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL---DRDGQIELA--LAAVTTRDAG 3337
D++ + P V W RDGV +P +T+ G + + R G
Sbjct: 51 DDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQG 110
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
+Y C ASN++G A S ++ ++ P+ P + P E E
Sbjct: 111 IYRCFASNKLGTA-MSHEIRLMA---EGAPKWPKETVKP----------------VEVEE 150
Query: 3398 GDTVIIECEVVGDPKP-DVYWL 3418
G++V++ C +P +YW+
Sbjct: 151 GESVVLPCNPPPSAEPLRIYWM 172
>M29273-1|AAA59545.1| 626|Homo sapiens MAG protein.
Length = 626
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/179 (31%), Positives = 83/179 (46%), Gaps = 23/179 (12%)
Query: 2594 PVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEV 2653
PV + A+EGS V L C S+ P +TW R+G +L R+ + + L+ LE+
Sbjct: 240 PVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVL------REAVAESLL-LEL 292
Query: 2654 LNAVPSDSAEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV- 2712
P++ Y+C EN G + + L V +P PT + T E E V
Sbjct: 293 EEVTPAEDGVYACLAENAYGQDNRTVGLSVM----YAPWKPT----VNGTMVAVEGETVS 344
Query: 2713 LECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAEN 2771
+ C + P P +T FK +KQI S Y++ +L + +PED G Y C AEN
Sbjct: 345 ILCSTQSNPDPILTIFK-EKQILSTVIYES------ELQLELPAVSPEDDGEYWCVAEN 396
Score = 48.0 bits (109), Expect = 6e-04
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 2582 EKRTLSRNSTRKPVFSTFLTDRTAVEGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYR 2641
+ RT+ + P T AVEG V + CS S+ DP +T ++ +L + Y
Sbjct: 314 DNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVI-YE 372
Query: 2642 KKLVDGLITLEVLNAVPSDSAEYSCTVENENGAISTSANLKV 2683
+L LE+ P D EY C EN+ G +T+ NL V
Sbjct: 373 SEL-----QLELPAVSPEDDGEYWCVAENQYGQRATAFNLSV 409
Score = 46.0 bits (104), Expect = 0.002
Identities = 49/206 (23%), Positives = 89/206 (43%), Gaps = 23/206 (11%)
Query: 3154 LKRERSAEVEGDYPPQFT-MRLRDRRVQATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDK 3212
L+ E A ++ YPP M ++ ++ V L C +PPP ++W +DG +
Sbjct: 226 LQFEGYASMDVKYPPVIVEMNSSVEAIEGSH-VSLLCGADSNPPPLLTWMRDGTVL---- 280
Query: 3213 RRNKYQDEQFHTLEIAPTNLDDGGVYEVTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCG 3272
R + E+ P + GVY A N G + GL V AP +
Sbjct: 281 REAVAESLLLELEEVTPA---EDGVYACLAENAYGQDNRTVGLSV------MYAP-WKPT 330
Query: 3273 LEPLYKLHEGDELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTLDRDGQIELALAAVT 3332
+ EG+ + I ++ P +T +++ ++ + T+ + +++L L AV+
Sbjct: 331 VNGTMVAVEGETVSILCSTQSNPDPILTIFKE-------KQILSTVIYESELQLELPAVS 383
Query: 3333 TRDAGVYTCTASNEVGRASTSGKVEV 3358
D G Y C A N+ G+ +T+ + V
Sbjct: 384 PEDDGEYWCVAENQYGQRATAFNLSV 409
Score = 37.5 bits (83), Expect = 0.84
Identities = 39/178 (21%), Positives = 74/178 (41%), Gaps = 14/178 (7%)
Query: 2606 VEGSRVKLTCSVISSSD---PTVTWYRNGVLLDNKLKYRKKLVDGL-ITLEVLNAVPSDS 2661
V G+ V+++C V + P ++W + L + + R + +G + + +L+ VP+
Sbjct: 150 VAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTRE 209
Query: 2662 AEYSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP 2721
A + + +T+ + Y S + PP + + + L C P
Sbjct: 210 AN-GHRLGCQASFPNTTLQFEGYASMDVK-YPPVIVEMNSSVEAIEGSHVSLLCGADSNP 267
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P +TW +D G +A+ + L ++ TP + G Y C AEN+ D T
Sbjct: 268 PPLLTWMRD-------GTVLREAVAESLL-LELEEVTPAEDGVYACLAENAYGQDNRT 317
Score = 35.1 bits (77), Expect = 4.5
Identities = 19/93 (20%), Positives = 41/93 (44%), Gaps = 8/93 (8%)
Query: 3050 PEFVDILPGQLKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCL 3109
P + + ++ + G +L C P P + WM++G + E L
Sbjct: 239 PPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAE--------SLLL 290
Query: 3110 TIKDINIDDEGRYSCEATNTHGKASTYARLAVV 3142
++++ ++G Y+C A N +G+ + L+V+
Sbjct: 291 ELEEVTPAEDGVYACLAENAYGQDNRTVGLSVM 323
Score = 34.7 bits (76), Expect = 5.9
Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 18/105 (17%)
Query: 2840 PTRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAA 2899
P + W+R+G + E V + L L L +VT E G+Y C A +A+G +
Sbjct: 268 PPLLTWMRDGTVLREA-------VAESLL-LELEEVTPAEDGVYACLAENAYGQDNRTVG 319
Query: 2900 ITVVQPSDLDGKPAVIVGRPEKDILISV-GEDINISFRTQGEPKP 2943
++V+ KP V +++V GE ++I TQ P P
Sbjct: 320 LSVMY---APWKPTV------NGTMVAVEGETVSILCSTQSNPDP 355
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 68.9 bits (161), Expect = 3e-10
Identities = 80/300 (26%), Positives = 122/300 (40%), Gaps = 38/300 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GETA L C V+G+P P V W NG VEE A ++ L + ++ D C
Sbjct: 342 GETARLDCQVQGRPQPEVTWRINGIPVEELA--KDQKYRIQRGALILSNVQPSDTMVTQC 399
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
EA N HG A + VV + AK+ + Q M ++ Y
Sbjct: 400 EARNRHGLLLANAYIYVV------QLPAKILTADN---------QTYMAVQG---STAY- 440
Query: 3185 VRLTCQVIGSPPPKVSWY-KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+ G+P P V W +DG V+ D+R Y + TL I +D G Y A
Sbjct: 441 --LLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAA 495
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV--GVTW 3301
N+ V+ L V + P + K +G + + PS+ +TW
Sbjct: 496 NDQNNVTIMANLKVTDATQITQGPR-----STIEK--KGSRVTFTCQASFDPSLQPSITW 548
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
DG L+ + DG+ L + ++ D G Y+C AS E+ + ++ V+G+
Sbjct: 549 RGDGRDLQELGDSDKYFIEDGR--LVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 606
Score = 60.9 bits (141), Expect = 8e-08
Identities = 71/310 (22%), Positives = 122/310 (39%), Gaps = 41/310 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A++G + L C PT+ W R +G + ++ Y+ TL++L D E
Sbjct: 249 ALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRATYQNHNK----TLQLLKVGEEDDGE 304
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G SA Y + EA+P + + + L+C+++G+P P
Sbjct: 305 YRCLAENSLG----SARHAYYVTVEAAPY---WLHKPQSHLYGPGETARLDCQVQGRPQP 357
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW + + + Q + + G L + N P D+ C+A N ++
Sbjct: 358 EVTWRINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 415
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
Q+ ++TA+ Y +G T L + G P
Sbjct: 416 VV----QLPAKILTADN-------------------QTYMAVQGSTAYLLCKAFGAPVPS 452
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+WL E T V ++ R F TL + D+ ++G Y C A + NV + A + V
Sbjct: 453 VQWLDE--DGTTVLQDER-FFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 509
Query: 2903 VQPSDLDGKP 2912
+ + P
Sbjct: 510 TDATQITQGP 519
Score = 60.9 bits (141), Expect = 8e-08
Identities = 72/299 (24%), Positives = 125/299 (41%), Gaps = 39/299 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK-KLVDGLITLEVLNAVPSDSAEYSC 2666
G +L C V P VTW NG+ ++ K +K ++ G + L N PSD+ C
Sbjct: 342 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILS--NVQPSDTMVTQC 399
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKI 2725
N +G + AN +Y +P + T+ + L C+ G P+P +
Sbjct: 400 EARNRHGLL--LANAYIY----VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 453
Query: 2726 TWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W +D + D R+ F A+G L I + D+G Y C A N + +T N
Sbjct: 454 QWLDEDGTTVLQDERF--FPYANGT--LGIRDLQANDTGRYFCLAAND--QNNVTIMANL 507
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
++ + T+ R ++E + G+ +T + LQ P+ +
Sbjct: 508 KVTDA--------TQITQGPRSTIEKK----GSRVT-FTCQASFDPSLQ------PS-IT 547
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +GR + E+ + + F+E G L + + ++ G Y+C A + V+ A + VV
Sbjct: 548 WRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVV 604
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 15/172 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWY-RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
AV+GS L C + P+V W +G + ++ +G + + L A +D+
Sbjct: 433 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP-YANGTLGIRDLQA--NDTGR 489
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP-- 2721
Y C N+ ++ ANLKV +A+ I T+ R T + + C+ P
Sbjct: 490 YFCLAANDQNNVTIMANLKV---TDATQI----TQGPRSTIEKKGSRVTFTCQASFDPSL 542
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P ITW D + + G +++ DG RL I + D G Y+C A +
Sbjct: 543 QPSITWRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTEL 592
Score = 52.8 bits (121), Expect = 2e-05
Identities = 75/306 (24%), Positives = 122/306 (39%), Gaps = 40/306 (13%)
Query: 2607 EGSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDS-AEYS 2665
EG V L C+ S++P ++ N +L K R + L N + SD+ ++Y
Sbjct: 145 EGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG-NLYFANVLTSDNHSDYI 203
Query: 2666 CTVENENGAI---STSANLKVYPSFEASPIPPTFTRSIRDTFHLAENE---LVLECRIRG 2719
C +L+V + P + HL + LVLEC G
Sbjct: 204 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 263
Query: 2720 QPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQIT 2779
P P I W + +P+D +A Y L + ED G Y C AENS+ + +
Sbjct: 264 FPTPTIKWLRPSGPMPAD---RATYQNHNK-TLQLLKVGEEDDGEYRCLAENSLGSARHA 319
Query: 2780 HFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGC 2839
++ VT E P++ + + G T L +++G
Sbjct: 320 YY--------------VTVEAA-----------PYWLHKPQSHLYGPGETARLDCQVQGR 354
Query: 2840 P-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNA 2898
P V W G V E+ ++ + +++G L LS+V +++ + C A + HG + NA
Sbjct: 355 PQPEVTWRINGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANA 412
Query: 2899 AITVVQ 2904
I VVQ
Sbjct: 413 YIYVVQ 418
Score = 46.8 bits (106), Expect = 0.001
Identities = 72/311 (23%), Positives = 113/311 (36%), Gaps = 39/311 (12%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L L G+ L C +G P P + W++ + A R T Q + L + + +D+
Sbjct: 247 LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMP--ADRATYQ--NHNKTLQLLKVGEEDD 302
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C A N+ G A +A V W L + +S Y P T
Sbjct: 303 GEYRCLAENSLGSAR-HAYYVTVEAAPYW-----LHKPQSHL----YGPGET-------- 344
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL CQV G P P+V+W +G V + KY+ ++ L ++ D V +
Sbjct: 345 -----ARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQ 398
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
ARN G + + + V + + Y +G + P V
Sbjct: 399 CEARNRHGLLLANAYIYV-----VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 453
Query: 3300 TWY-RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W DG + R + L + + D G Y C A+N+ + ++V
Sbjct: 454 QWLDEDGTTVLQDERFFPYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 509
Query: 3359 IGTDQ-TSEPR 3368
Q T PR
Sbjct: 510 TDATQITQGPR 520
Score = 43.6 bits (98), Expect = 0.013
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 32/235 (13%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
P+ L C G P P + W + + D R YQ+ TL++ +D G Y A
Sbjct: 254 PLVLECIAEGFPTPTIKWLRPSGPMPAD--RATYQNHN-KTLQLLKVGEEDDGEYRCLAE 310
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+ G+ + V+ P+ LY G+ R+ V+ P VTW
Sbjct: 311 NSLGSARHAYYVTVEAAPYWLHKPQ-----SHLY--GPGETARLDCQVQGRPQPEVTWRI 363
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+G+ + + + G L L+ V D V C A N G + + V+
Sbjct: 364 NGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---- 417
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
++P +++ D ++ A +G T + C+ G P P V WL
Sbjct: 418 ----QLPAKILTAD------------NQTYMAVQGSTAYLLCKAFGAPVPSVQWL 456
Score = 37.5 bits (83), Expect = 0.84
Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 10/122 (8%)
Query: 2964 VSLAWPKSDPQTTAPVLAYKVESWLIGAEGGARWVELGITPLNSFDA-FNLKQGEEYHFR 3022
V ++W ++ AP+ Y +E G +W LG P N L Y FR
Sbjct: 626 VRVSWSPAEDHN-APIEKYDIEFEDKEMAPG-KWYSLGKVPGNQTSTTLKLSPYVHYTFR 683
Query: 3023 VTPRNRYGWGESSQTSSSIGVGLAGDRPEFVDILPGQLKILAGETANLTCSVKGKPVPGV 3082
VT N+YG GE S S ++ A VD+ K ET N+ + KP+ +
Sbjct: 684 VTAINKYGPGEPSPVSETVVTPEAAPEKNPVDV-----KGEGNETTNMV--ITWKPLRWM 736
Query: 3083 VW 3084
W
Sbjct: 737 DW 738
Score = 35.5 bits (78), Expect = 3.4
Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 26/142 (18%)
Query: 3283 DELRISAVVEAYPSVGVTWYRDGVRLRPSRRAIMTL---DRDGQIELA--LAAVTTRDAG 3337
D++ + P V W RDGV +P +T+ G + + R G
Sbjct: 46 DDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQG 105
Query: 3338 VYTCTASNEVGRASTSGKVEVIGTDQTSEPRIPPVVISPDVPYSKEPMFIRKPRSSEARE 3397
+Y C ASN++G A S ++ ++ P+ P + P E E
Sbjct: 106 IYRCFASNKLGTA-MSHEIRLMA---EGAPKWPKETVKP----------------VEVEE 145
Query: 3398 GDTVIIECEVVGDPKP-DVYWL 3418
G++V++ C +P +YW+
Sbjct: 146 GESVVLPCNPPPSAEPLRIYWM 167
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 68.9 bits (161), Expect = 3e-10
Identities = 80/300 (26%), Positives = 122/300 (40%), Gaps = 38/300 (12%)
Query: 3065 GETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDEGRYSC 3124
GETA L C V+G+P P V W NG VEE A ++ L + ++ D C
Sbjct: 179 GETARLDCQVQGRPQPEVTWRINGIPVEELA--KDQKYRIQRGALILSNVQPSDTMVTQC 236
Query: 3125 EATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRVQATYP 3184
EA N HG A + VV + AK+ + Q M ++ Y
Sbjct: 237 EARNRHGLLLANAYIYVV------QLPAKILTADN---------QTYMAVQG---STAY- 277
Query: 3185 VRLTCQVIGSPPPKVSWY-KDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
L C+ G+P P V W +DG V+ D+R Y + TL I +D G Y A
Sbjct: 278 --LLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAA 332
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSV--GVTW 3301
N+ V+ L V + P + K +G + + PS+ +TW
Sbjct: 333 NDQNNVTIMANLKVKDATQITQGPR-----STIEK--KGSRVTFTCQASFDPSLQPSITW 385
Query: 3302 YRDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGT 3361
DG L+ + DG+ L + ++ D G Y+C AS E+ + ++ V+G+
Sbjct: 386 RGDGRDLQELGDSDKYFIEDGR--LVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 443
Score = 62.1 bits (144), Expect = 3e-08
Identities = 72/299 (24%), Positives = 126/299 (42%), Gaps = 39/299 (13%)
Query: 2608 GSRVKLTCSVISSSDPTVTWYRNGVLLDNKLKYRK-KLVDGLITLEVLNAVPSDSAEYSC 2666
G +L C V P VTW NG+ ++ K +K ++ G + L N PSD+ C
Sbjct: 179 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILS--NVQPSDTMVTQC 236
Query: 2667 TVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELV-LECRIRGQPLPKI 2725
N +G + AN +Y +P + T+ + L C+ G P+P +
Sbjct: 237 EARNRHGLL--LANAYIY----VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 290
Query: 2726 TWFKDD-KQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVNF 2784
W +D + D R+ F A+G L I + D+G Y C A N + +T N
Sbjct: 291 QWLDEDGTTVLQDERF--FPYANGT--LGIRDLQANDTGRYFCLAAND--QNNVTIMANL 344
Query: 2785 TGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPTRVE 2844
+++ + T+ R ++E + G+ +T + LQ P+ +
Sbjct: 345 KVKDA--------TQITQGPRSTIEKK----GSRVT-FTCQASFDPSLQ------PS-IT 384
Query: 2845 WLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITVV 2903
W +GR + E+ + + F+E G L + + ++ G Y+C A + V+ A + VV
Sbjct: 385 WRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVV 441
Score = 60.9 bits (141), Expect = 8e-08
Identities = 71/310 (22%), Positives = 123/310 (39%), Gaps = 41/310 (13%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWYR-NGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
A++G + L C PT+ W R +G + +++ Y+ TL++L D E
Sbjct: 86 ALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNK----TLQLLKVGEEDDGE 141
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQPLP 2723
Y C EN G SA Y + EA+P + + + L+C+++G+P P
Sbjct: 142 YRCLAENSLG----SARHAYYVTVEAAPY---WLHKPQSHLYGPGETARLDCQVQGRPQP 194
Query: 2724 KITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSVWTDQITHFVN 2783
++TW + + + Q + + G L + N P D+ C+A N ++
Sbjct: 195 EVTWRINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252
Query: 2784 FTGRESQVSPNVVTAEKTRIARQSLESRRPHFGNVLTDYQVARGGTIGLQVEIRGCPT-R 2842
Q+ ++TA+ Y +G T L + G P
Sbjct: 253 VV----QLPAKILTADN-------------------QTYMAVQGSTAYLLCKAFGAPVPS 289
Query: 2843 VEWLREGRSVTEVYRNARVFVEQGLYTLALSDVTETESGLYTCRAWSAHGNVDMNAAITV 2902
V+WL E T V ++ R F TL + D+ ++G Y C A + NV + A + V
Sbjct: 290 VQWLDE--DGTTVLQDER-FFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 2903 VQPSDLDGKP 2912
+ + P
Sbjct: 347 KDATQITQGP 356
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 15/172 (8%)
Query: 2605 AVEGSRVKLTCSVISSSDPTVTWY-RNGVLLDNKLKYRKKLVDGLITLEVLNAVPSDSAE 2663
AV+GS L C + P+V W +G + ++ +G + + L A +D+
Sbjct: 270 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP-YANGTLGIRDLQA--NDTGR 326
Query: 2664 YSCTVENENGAISTSANLKVYPSFEASPIPPTFTRSIRDTFHLAENELVLECRIRGQP-- 2721
Y C N+ ++ ANLKV +A+ I T+ R T + + C+ P
Sbjct: 327 YFCLAANDQNNVTIMANLKVK---DATQI----TQGPRSTIEKKGSRVTFTCQASFDPSL 379
Query: 2722 LPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDNPTPEDSGTYTCKAENSV 2773
P ITW D + + G +++ DG RL I + D G Y+C A +
Sbjct: 380 QPSITWRGDGRDLQELGDSDKYFIEDG--RLVIHSLDYSDQGNYSCVASTEL 429
Score = 47.6 bits (108), Expect = 8e-04
Identities = 55/209 (26%), Positives = 86/209 (41%), Gaps = 32/209 (15%)
Query: 2697 TRSIRDTFHLAENELVLECRIRGQPLPKITWFKDDKQIPSDGRYQAFYLADGVCRLAIDN 2756
T S L LVLEC G P P I W + +P+D + Y L +
Sbjct: 78 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNK-TLQLLK 133
Query: 2757 PTPEDSGTYTCKAENSVWTDQITHFVNFTGRESQVSPNVVTAEKTRIARQSLESRRPHFG 2816
ED G Y C AENS+ + + ++ VT E P++
Sbjct: 134 VGEEDDGEYRCLAENSLGSARHAYY--------------VTVEAA-----------PYWL 168
Query: 2817 NVLTDYQVARGGTIGLQVEIRGCP-TRVEWLREGRSVTEVYRNARVFVEQGLYTLALSDV 2875
+ + G T L +++G P V W G V E+ ++ + +++G L LS+V
Sbjct: 169 HKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--ALILSNV 226
Query: 2876 TETESGLYTCRAWSAHGNVDMNAAITVVQ 2904
+++ + C A + HG + NA I VVQ
Sbjct: 227 QPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Score = 46.8 bits (106), Expect = 0.001
Identities = 72/311 (23%), Positives = 114/311 (36%), Gaps = 39/311 (12%)
Query: 3060 LKILAGETANLTCSVKGKPVPGVVWMKNGHEVEEEAGRMTSQFNGFDCCLTIKDINIDDE 3119
L L G+ L C +G P P + W++ + A R+T Q + L + + +D+
Sbjct: 84 LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMP--ADRVTYQ--NHNKTLQLLKVGEEDD 139
Query: 3120 GRYSCEATNTHGKASTYARLAVVTDRTVWEADAKLKRERSAEVEGDYPPQFTMRLRDRRV 3179
G Y C A N+ G A +A V W L + +S Y P T
Sbjct: 140 GEYRCLAENSLGSAR-HAYYVTVEAAPYW-----LHKPQSHL----YGPGET-------- 181
Query: 3180 QATYPVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYE 3239
RL CQV G P P+V+W +G V + KY+ ++ L ++ D V +
Sbjct: 182 -----ARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQ 235
Query: 3240 VTARNNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGV 3299
ARN G + + + V + + Y +G + P V
Sbjct: 236 CEARNRHGLLLANAYIYV-----VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSV 290
Query: 3300 TWY-RDGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEV 3358
W DG + R + L + + D G Y C A+N+ + ++V
Sbjct: 291 QWLDEDGTTVLQDERFFPYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 3359 IGTDQ-TSEPR 3368
Q T PR
Sbjct: 347 KDATQITQGPR 357
Score = 43.2 bits (97), Expect = 0.017
Identities = 54/235 (22%), Positives = 89/235 (37%), Gaps = 32/235 (13%)
Query: 3184 PVRLTCQVIGSPPPKVSWYKDGEEVVYDKRRNKYQDEQFHTLEIAPTNLDDGGVYEVTAR 3243
P+ L C G P P + W + + D R YQ+ TL++ +D G Y A
Sbjct: 91 PLVLECIAEGFPTPTIKWLRPSGPMPAD--RVTYQNHN-KTLQLLKVGEEDDGEYRCLAE 147
Query: 3244 NNSGAVSCHCGLVVDKGIRAYVAPEFCCGLEPLYKLHEGDELRISAVVEAYPSVGVTWYR 3303
N+ G+ + V+ P+ LY G+ R+ V+ P VTW
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHKPQ-----SHLY--GPGETARLDCQVQGRPQPEVTWRI 200
Query: 3304 DGVRLRPSRRAIMTLDRDGQIELALAAVTTRDAGVYTCTASNEVGRASTSGKVEVIGTDQ 3363
+G+ + + + G L L+ V D V C A N G + + V+
Sbjct: 201 NGIPVEELAKDQKYRIQRG--ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---- 254
Query: 3364 TSEPRIPPVVISPDVPYSKEPMFIRKPRSSEAREGDTVIIECEVVGDPKPDVYWL 3418
++P +++ D ++ A +G T + C+ G P P V WL
Sbjct: 255 ----QLPAKILTAD------------NQTYMAVQGSTAYLLCKAFGAPVPSVQWL 293
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.309 0.127 0.345
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 377,490,960
Number of Sequences: 224733
Number of extensions: 15496207
Number of successful extensions: 115791
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 762
Number of HSP's successfully gapped in prelim test: 1859
Number of HSP's that attempted gapping in prelim test: 73850
Number of HSP's gapped (non-prelim): 31342
length of query: 3427
length of database: 73,234,838
effective HSP length: 104
effective length of query: 3323
effective length of database: 49,862,606
effective search space: 165693439738
effective search space used: 165693439738
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.7 bits)
S2: 75 (34.3 bits)
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