Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002033-TA|BGIBMGA002033-PA|IPR007110|Immunoglobulin-
like, IPR003599|Immunoglobulin subtype, IPR013098|Immunoglobulin I-set
(354 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 104 5e-22
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 103 7e-22
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 91 7e-18
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 90 9e-18
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 90 9e-18
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 90 9e-18
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 88 4e-17
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 82 3e-15
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 81 6e-15
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 81 8e-15
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 81 8e-15
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 81 8e-15
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 80 1e-14
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 79 2e-14
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 79 2e-14
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 79 2e-14
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 78 4e-14
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 78 4e-14
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 78 4e-14
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 78 4e-14
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 78 4e-14
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 78 4e-14
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 78 4e-14
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 76 2e-13
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 73 1e-12
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 73 1e-12
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 73 1e-12
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 73 2e-12
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 71 5e-12
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 71 5e-12
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 71 5e-12
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 71 5e-12
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 71 6e-12
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 71 6e-12
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 71 6e-12
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 71 6e-12
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 71 6e-12
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 70 1e-11
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 70 1e-11
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 69 2e-11
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 66 2e-10
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 66 2e-10
BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein pr... 65 4e-10
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 64 5e-10
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 64 5e-10
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 64 5e-10
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 64 5e-10
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 64 9e-10
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 64 9e-10
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 64 9e-10
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 63 2e-09
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 63 2e-09
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 63 2e-09
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 63 2e-09
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 63 2e-09
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 62 2e-09
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 62 3e-09
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 62 3e-09
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 62 3e-09
AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific tit... 62 3e-09
AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein. 62 3e-09
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 62 3e-09
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 62 4e-09
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 62 4e-09
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 61 5e-09
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 61 5e-09
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 61 7e-09
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 61 7e-09
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 61 7e-09
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 61 7e-09
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 60 9e-09
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 60 2e-08
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 60 2e-08
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 60 2e-08
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 60 2e-08
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 60 2e-08
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 60 2e-08
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 59 2e-08
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 59 2e-08
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 59 2e-08
AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein. 59 3e-08
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 58 6e-08
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 58 6e-08
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 58 6e-08
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 58 6e-08
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 57 1e-07
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 57 1e-07
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 57 1e-07
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 57 1e-07
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 57 1e-07
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 57 1e-07
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 57 1e-07
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 57 1e-07
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 57 1e-07
DQ248309-1|ABB55264.1| 851|Homo sapiens rhabdomyosarcoma antige... 56 1e-07
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 56 1e-07
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 56 1e-07
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 56 1e-07
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 56 1e-07
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 56 1e-07
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 56 1e-07
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 56 2e-07
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 56 2e-07
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 56 2e-07
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 56 2e-07
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 56 2e-07
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 56 2e-07
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 56 2e-07
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 56 2e-07
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 56 2e-07
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 56 2e-07
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 56 2e-07
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 56 2e-07
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 56 2e-07
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 56 2e-07
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 56 2e-07
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 56 2e-07
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 55 3e-07
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 55 3e-07
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 55 3e-07
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 55 4e-07
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 54 6e-07
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 54 6e-07
BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein pr... 54 6e-07
AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens ... 54 6e-07
BC043916-1|AAH43916.1| 767|Homo sapiens OBSCN protein protein. 54 8e-07
AL353593-2|CAI19284.1| 416|Homo sapiens obscurin, cytoskeletal ... 54 8e-07
AL353593-1|CAI19283.1| 709|Homo sapiens obscurin, cytoskeletal ... 54 8e-07
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 54 8e-07
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 53 1e-06
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 53 1e-06
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 53 1e-06
BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein. 53 1e-06
BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kin... 53 1e-06
BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kin... 53 1e-06
BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein. 53 1e-06
AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein ... 53 1e-06
AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein ... 53 1e-06
AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle... 53 1e-06
AB046776-1|BAB13382.1| 1596|Homo sapiens KIAA1556 protein protein. 53 1e-06
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 53 2e-06
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 52 2e-06
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 52 2e-06
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 52 3e-06
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 52 3e-06
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 52 3e-06
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 52 3e-06
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 52 3e-06
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 52 3e-06
AY302131-1|AAP59845.1| 593|Homo sapiens NEPH1 protein protein. 52 3e-06
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 52 3e-06
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 52 3e-06
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 52 3e-06
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 52 3e-06
AL139010-2|CAH73882.1| 593|Homo sapiens kin of IRRE like (Droso... 52 3e-06
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 52 3e-06
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 52 3e-06
AJ314905-1|CAC85752.1| 2212|Homo sapiens obscurin protein. 52 3e-06
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 52 3e-06
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 52 4e-06
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 52 4e-06
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 52 4e-06
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 52 4e-06
AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens ... 52 4e-06
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 51 5e-06
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 51 7e-06
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 51 7e-06
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 51 7e-06
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 51 7e-06
BC125103-1|AAI25104.1| 414|Homo sapiens CADM1 protein protein. 50 9e-06
BC125102-1|AAI25103.1| 415|Homo sapiens CADM1 protein protein. 50 9e-06
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 50 9e-06
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 50 9e-06
BC047021-1|AAH47021.1| 387|Homo sapiens CADM1 protein protein. 50 9e-06
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 50 9e-06
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 50 9e-06
X80026-1|CAA56327.1| 588|Homo sapiens B-CAM protein. 50 2e-05
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 50 2e-05
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 50 2e-05
BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein. 50 2e-05
BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein. 50 2e-05
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 50 2e-05
BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kin... 50 2e-05
BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kin... 50 2e-05
AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein. 50 2e-05
AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein ... 50 2e-05
AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein ... 50 2e-05
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 50 2e-05
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 50 2e-05
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 49 2e-05
X83425-1|CAA58449.1| 628|Homo sapiens Lutheran blood group glyc... 49 3e-05
BC050450-1|AAH50450.1| 628|Homo sapiens basal cell adhesion mol... 49 3e-05
AY845133-1|AAV88096.1| 628|Homo sapiens Lutheran blood group (A... 49 3e-05
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 49 3e-05
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 49 3e-05
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 49 3e-05
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 49 3e-05
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 49 3e-05
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 48 4e-05
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 48 4e-05
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 48 4e-05
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 48 5e-05
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 48 5e-05
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 48 5e-05
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 48 5e-05
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 48 5e-05
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 48 5e-05
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 48 5e-05
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 48 5e-05
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 48 5e-05
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 48 5e-05
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 48 5e-05
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 48 5e-05
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 48 7e-05
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 47 9e-05
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 47 9e-05
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 47 9e-05
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 47 9e-05
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 47 9e-05
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 47 1e-04
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 47 1e-04
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 46 2e-04
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 46 2e-04
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 46 2e-04
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 46 2e-04
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 46 2e-04
AK023854-1|BAB14704.1| 442|Homo sapiens .117). protein. 46 2e-04
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 46 2e-04
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 46 2e-04
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 46 2e-04
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 46 2e-04
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 46 2e-04
AB094146-1|BAC66178.1| 333|Homo sapiens secretory isoform of TS... 46 2e-04
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 46 3e-04
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 46 3e-04
AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens ... 46 3e-04
AC115538-1|AAY40987.1| 103|Homo sapiens unknown protein. 46 3e-04
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 45 4e-04
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 45 4e-04
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 45 4e-04
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 45 4e-04
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 45 4e-04
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 45 4e-04
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 45 4e-04
AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 45 4e-04
BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein pr... 45 5e-04
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 45 5e-04
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 45 5e-04
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 45 5e-04
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 45 5e-04
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 45 5e-04
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 45 5e-04
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 45 5e-04
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 45 5e-04
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 45 5e-04
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 45 5e-04
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 45 5e-04
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 45 5e-04
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 45 5e-04
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 45 5e-04
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 45 5e-04
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 45 5e-04
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 44 6e-04
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 44 6e-04
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 44 6e-04
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 44 6e-04
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 44 6e-04
AK075502-1|BAC11657.1| 443|Homo sapiens protein ( Homo sapiens ... 44 6e-04
AJ314903-1|CAC85750.1| 542|Homo sapiens obscurin protein. 44 6e-04
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 44 6e-04
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 44 6e-04
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 44 6e-04
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 44 6e-04
CR457157-1|CAG33438.1| 442|Homo sapiens IGSF4 protein. 44 8e-04
AY358334-1|AAQ88700.1| 440|Homo sapiens IGSF4 protein. 44 8e-04
AF132811-1|AAF69029.1| 442|Homo sapiens nectin-like protein 2 p... 44 8e-04
AB017563-1|BAA75822.1| 442|Homo sapiens IGSF4 protein. 44 8e-04
BC014276-1|AAH14276.2| 417|Homo sapiens LRIG1 protein protein. 44 0.001
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 44 0.001
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 43 0.002
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 43 0.002
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 43 0.002
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 43 0.002
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 43 0.002
AY328482-1|AAP97010.1| 571|Homo sapiens MAM domain containing 1... 42 0.002
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 42 0.003
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 42 0.003
BC109193-1|AAI09194.1| 757|Homo sapiens KIRREL protein protein. 42 0.003
BC109192-1|AAI09193.1| 757|Homo sapiens KIRREL protein protein. 42 0.003
AY017369-1|AAK00529.1| 605|Homo sapiens NEPH1 protein. 42 0.003
AL139010-1|CAH73881.1| 757|Homo sapiens kin of IRRE like (Droso... 42 0.003
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 42 0.003
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 42 0.003
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 42 0.004
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 42 0.004
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 42 0.004
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 42 0.004
BC112138-1|AAI12139.1| 435|Homo sapiens CADM2 protein protein. 42 0.004
BC112136-1|AAI12137.1| 435|Homo sapiens CADM2 protein protein. 42 0.004
BC105999-1|AAI06000.1| 404|Homo sapiens CADM2 protein protein. 42 0.004
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 42 0.004
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 42 0.004
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 42 0.004
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 42 0.004
X68203-1|CAA48290.1| 1304|Homo sapiens FTL4 protein. 41 0.006
U43143-1|AAA85215.1| 1298|Homo sapiens Flt4 protein. 41 0.006
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 41 0.006
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 41 0.006
AC005525-1|AAC32740.1| 381|Homo sapiens F22162_1 protein. 41 0.006
AB209637-1|BAD92874.1| 649|Homo sapiens Vascular endothelial gr... 41 0.006
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 41 0.008
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 41 0.008
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 41 0.008
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 41 0.008
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 41 0.008
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 40 0.010
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 40 0.010
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 40 0.010
BC025310-1|AAH25310.1| 542|Homo sapiens LRFN1 protein protein. 40 0.010
BC014678-1|AAH14678.1| 450|Homo sapiens LRFN1 protein protein. 40 0.010
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 40 0.010
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 40 0.010
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 40 0.010
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 40 0.010
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 40 0.010
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 40 0.010
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 40 0.013
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 40 0.013
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 40 0.013
BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth facto... 40 0.013
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 40 0.013
AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein. 40 0.013
AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens ... 40 0.013
AJ314904-1|CAC85751.1| 658|Homo sapiens obscurin protein. 40 0.013
AJ314901-1|CAC85749.1| 183|Homo sapiens obscurin protein. 40 0.013
AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein. 40 0.013
AJ001054-1|CAA04504.1| 148|Homo sapiens NrCAM protein protein. 40 0.013
AF538973-1|AAN16368.1| 437|Homo sapiens nectin-like protein 3 p... 40 0.013
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 40 0.013
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 40 0.013
AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor r... 40 0.013
AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth facto... 40 0.013
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 40 0.013
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 40 0.013
AB209441-1|BAD92678.1| 879|Homo sapiens fibroblast growth facto... 40 0.013
BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein. 40 0.018
BC101801-1|AAI01802.1| 778|Homo sapiens kin of IRRE like 3 prot... 40 0.018
BC101775-1|AAI01776.1| 778|Homo sapiens kin of IRRE like 3 (Dro... 40 0.018
AY358743-1|AAQ89103.1| 600|Homo sapiens NEPH2 protein. 40 0.018
AF480410-1|AAN73042.1| 778|Homo sapiens NPEH2 protein. 40 0.018
AB058770-1|BAB47496.1| 779|Homo sapiens KIAA1867 protein protein. 40 0.018
U57099-1|AAC50599.1| 113|Homo sapiens APEG-1 protein protein. 39 0.023
CR542201-1|CAG46998.1| 113|Homo sapiens APEG1 protein. 39 0.023
BC006346-1|AAH06346.1| 113|Homo sapiens SPEG protein protein. 39 0.023
AK128689-1|BAC87572.1| 175|Homo sapiens protein ( Homo sapiens ... 39 0.023
AK126500-1|BAC86568.1| 170|Homo sapiens protein ( Homo sapiens ... 39 0.023
AC053503-3|AAY15052.1| 113|Homo sapiens unknown protein. 39 0.023
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 39 0.023
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 39 0.031
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 39 0.031
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 39 0.031
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 39 0.031
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 39 0.031
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 39 0.031
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 39 0.031
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 39 0.031
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 39 0.031
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 39 0.031
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 39 0.031
M34188-1|AAA35839.1| 300|Homo sapiens protein ( Human fibroblas... 39 0.031
M34187-1|AAA35838.1| 302|Homo sapiens protein ( Human fibroblas... 39 0.031
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 39 0.031
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 39 0.031
BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein. 39 0.031
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 39 0.031
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 39 0.031
AY211921-1|AAO65174.1| 294|Homo sapiens sarcoma antigen NY-SAR-... 39 0.031
AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member... 39 0.031
AL049553-2|CAI20461.1| 957|Homo sapiens MAM domain containing g... 39 0.031
AF478693-1|AAM77220.1| 955|Homo sapiens glycosyl-phosphatidyl-i... 39 0.031
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 39 0.031
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 39 0.031
U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H ... 38 0.053
DQ464902-1|ABE97925.1| 675|Homo sapiens nexilin protein. 38 0.053
BC114445-1|AAI14446.1| 567|Homo sapiens NEXN protein protein. 38 0.053
BC114444-1|AAI14445.1| 567|Homo sapiens NEXN protein protein. 38 0.053
BC111395-1|AAI11396.1| 554|Homo sapiens NEXN protein protein. 38 0.053
BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein ... 38 0.053
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 38 0.053
AY358132-1|AAQ88499.1| 352|Homo sapiens DMML2433 protein. 38 0.053
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 38 0.053
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 38 0.053
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 38 0.053
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 38 0.053
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 38 0.053
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 38 0.053
AF114264-1|AAD29607.1| 448|Homo sapiens unknown protein. 38 0.053
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 38 0.053
Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C ... 38 0.071
X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding pr... 38 0.071
X69878-1|CAA49505.1| 1298|Homo sapiens protein ( H.sapiens Flt4 ... 38 0.071
U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding pr... 38 0.071
U89336-3|AAB47491.1| 404|Homo sapiens receptor for advanced gly... 38 0.071
M91211-1|AAA03574.1| 404|Homo sapiens receptor for advanced gly... 38 0.071
L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhes... 38 0.071
D28769-2|BAA05958.1| 404|Homo sapiens receptor of advanced glyc... 38 0.071
DQ104254-1|AAZ32415.1| 303|Homo sapiens receptor for advanced g... 38 0.071
DQ104252-1|AAZ32413.1| 390|Homo sapiens receptor for advanced g... 38 0.071
BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein pr... 38 0.071
BX284686-17|CAM26225.1| 347|Homo sapiens advanced glycosylation... 38 0.071
BX284686-16|CAM26224.1| 404|Homo sapiens advanced glycosylation... 38 0.071
BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding protein/... 38 0.071
BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding protein/... 38 0.071
BC113963-1|AAI13964.1| 262|Homo sapiens CADM4 protein protein. 38 0.071
BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding protein/... 38 0.071
BC046109-1|AAH46109.1| 459|Homo sapiens PTK7 protein protein. 38 0.071
BC020669-1|AAH20669.1| 404|Homo sapiens advanced glycosylation ... 38 0.071
AY755628-1|AAX07281.1| 347|Homo sapiens receptor for advanced g... 38 0.071
AY755624-1|AAX07277.1| 390|Homo sapiens receptor for advanced g... 38 0.071
AY755622-1|AAX07275.1| 363|Homo sapiens receptor for advanced g... 38 0.071
AY755621-1|AAX07274.1| 420|Homo sapiens receptor for advanced g... 38 0.071
AY755620-1|AAX07273.1| 347|Homo sapiens receptor for advanced g... 38 0.071
AY755619-1|AAX07272.1| 404|Homo sapiens receptor for advanced g... 38 0.071
AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein ... 38 0.071
AY233383-1|AAO89505.1| 1363|Homo sapiens VEGFR3 long form protein. 38 0.071
AY233382-1|AAO89504.1| 1298|Homo sapiens VEGFR3 short form protein. 38 0.071
AL845464-17|CAM25716.1| 347|Homo sapiens advanced glycosylation... 38 0.071
AL845464-16|CAI41810.1| 404|Homo sapiens advanced glycosylation... 38 0.071
AL662884-22|CAM25647.1| 347|Homo sapiens advanced glycosylation... 38 0.071
AL662884-20|CAI18354.1| 404|Homo sapiens advanced glycosylation... 38 0.071
AL662830-4|CAM24893.1| 347|Homo sapiens advanced glycosylation ... 38 0.071
AL662830-3|CAI17536.1| 404|Homo sapiens advanced glycosylation ... 38 0.071
AK223126-1|BAD96846.1| 300|Homo sapiens fibroblast growth facto... 38 0.071
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 38 0.071
AF536237-1|AAQ10686.1| 147|Homo sapiens advanced glycosylation ... 38 0.071
AF363368-1|AAM60750.1| 388|Homo sapiens TSLC1-like 2 protein. 38 0.071
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 38 0.071
AC104651-1|AAX93144.1| 432|Homo sapiens unknown protein. 38 0.071
AB061669-1|BAC65466.1| 303|Homo sapiens N-terminal truncated fo... 38 0.071
AB061668-1|BAC65465.1| 347|Homo sapiens soluble form of recepto... 38 0.071
AB036432-1|BAA89369.1| 404|Homo sapiens advanced glycation endp... 38 0.071
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 37 0.093
BC030143-1|AAH30143.1| 813|Homo sapiens mucosa associated lymph... 37 0.093
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 37 0.093
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 37 0.093
AL356276-1|CAH73052.1| 366|Homo sapiens Fc receptor-like 1 prot... 37 0.093
AL139409-1|CAH70232.1| 366|Homo sapiens Fc receptor-like 1 prot... 37 0.093
AK096690-1|BAC04842.1| 366|Homo sapiens protein ( Homo sapiens ... 37 0.093
AF316597-1|AAG38589.1| 824|Homo sapiens paracaspase protein. 37 0.093
AF130356-1|AAD38507.2| 824|Homo sapiens MALT lymphoma associate... 37 0.093
AF123094-1|AAD46161.1| 1140|Homo sapiens API2-MLT fusion protein... 37 0.093
AB026118-1|BAA83099.1| 813|Homo sapiens MALT1 protein. 37 0.093
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 37 0.12
M22734-1|AAA60048.1| 1089|Homo sapiens platelet-derived growth f... 37 0.12
M21574-1|AAA96715.1| 1089|Homo sapiens platelet-derived growth f... 37 0.12
D50017-1|BAA08742.1| 1089|Homo sapiens alpha-platelet-derived gr... 37 0.12
BC082969-1|AAH82969.1| 446|Homo sapiens KIRREL protein protein. 37 0.12
BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding protein/... 37 0.12
BC067097-1|AAH67097.1| 446|Homo sapiens KIRREL protein protein. 37 0.12
BC063414-1|AAH63414.1| 743|Homo sapiens PDGFRA protein protein. 37 0.12
BC051356-1|AAH51356.1| 446|Homo sapiens KIRREL protein protein. 37 0.12
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 37 0.12
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 36 0.16
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 36 0.16
AK057954-1|BAB71622.1| 505|Homo sapiens protein ( Homo sapiens ... 36 0.16
AK027852-1|BAB55411.1| 792|Homo sapiens protein ( Homo sapiens ... 36 0.16
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 36 0.22
X53051-1|CAA37218.1| 739|Homo sapiens precursor peptide protein. 36 0.22
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 36 0.22
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 36 0.22
M73255-1|AAA61270.1| 739|Homo sapiens vascular cell adhesion mo... 36 0.22
M60335-1|AAA61269.1| 739|Homo sapiens vascular cell adhesion mo... 36 0.22
M30257-1|AAA51917.1| 647|Homo sapiens VCAM1 protein. 36 0.22
BC100788-1|AAI00789.1| 467|Homo sapiens C9orf94 protein protein. 36 0.22
BC085003-1|AAH85003.1| 739|Homo sapiens vascular cell adhesion ... 36 0.22
BC068490-1|AAH68490.2| 739|Homo sapiens vascular cell adhesion ... 36 0.22
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 36 0.22
BC017276-1|AAH17276.3| 739|Homo sapiens vascular cell adhesion ... 36 0.22
AL158150-1|CAM14351.1| 275|Homo sapiens chromosome 9 open readi... 36 0.22
AK223266-1|BAD96986.1| 739|Homo sapiens vascular cell adhesion ... 36 0.22
AK222680-1|BAD96400.1| 626|Homo sapiens myelin associated glyco... 36 0.22
AK096821-1|BAC04869.1| 405|Homo sapiens protein ( Homo sapiens ... 36 0.22
AK092602-1|BAC03925.1| 262|Homo sapiens protein ( Homo sapiens ... 36 0.22
AF536818-1|AAM96190.1| 739|Homo sapiens vascular cell adhesion ... 36 0.22
AC023270-2|AAX88845.1| 405|Homo sapiens unknown protein. 36 0.22
M29273-1|AAA59545.1| 626|Homo sapiens MAG protein. 36 0.28
BC132902-1|AAI32903.1| 354|Homo sapiens myosin binding protein ... 36 0.28
BC132900-1|AAI32901.1| 354|Homo sapiens myosin binding protein ... 36 0.28
BC093045-1|AAH93045.1| 582|Homo sapiens myelin associated glyco... 36 0.28
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 104 bits (249), Expect = 5e-22
Identities = 84/288 (29%), Positives = 132/288 (45%), Gaps = 26/288 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ-DLTVKVG 122
LTV GD G YT ASN AG D+ +L V ++PP F+++L+ VK
Sbjct: 3934 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGV--------QEPPRFIKKLEPSRIVKQD 3985
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
TR+ +I S E KV WY++E + E+ + + S G +TC A
Sbjct: 3986 EFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEA 4045
Query: 183 ENVGGRASCSAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
N G AS S L V P + K+P +E L+ V LEC++ G P + W+KD
Sbjct: 4046 HNAAGSASSSTSLKVKEPPIFRKKPHPIETLKG-----ADVHLECELQGTPPFHVSWYKD 4100
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
RE+++G + + + TS+ +A + +G Y + VG + GS
Sbjct: 4101 KRELRSGKKYKIMSE-NFLTSIHILNVDAAD-IGE-YQCKATNDVGSDTCVGS------- 4150
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
++ + PP F ++L D + + L I P SVVW+ +G++
Sbjct: 4151 IALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAE-PISVVWFKDKGEI 4197
Score = 93.9 bits (223), Expect = 8e-19
Identities = 82/280 (29%), Positives = 126/280 (45%), Gaps = 26/280 (9%)
Query: 72 GDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV-KVGTRTRFLVE 130
GD+G YT QA+N G D +L V ++PP F+++L+ V K G + +
Sbjct: 3001 GDSGQYTCQATNDVGKDMCSAQLSV--------KEPPKFVKKLEASKVAKQGESIQLECK 3052
Query: 131 IISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRAS 190
I S E KV+W+RN+ L E+ + ++ S G + C A N G AS
Sbjct: 3053 ISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDAS 3112
Query: 191 CSAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD 249
CS L V P + ++P V L+ V L+C++ G P + W KD ++++
Sbjct: 3113 CSTALTVKAPPVFTQKPSPVGALKG-----SDVILQCEISGTPPFEVVWVKDRKQVRNSK 3167
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
F +T+ D T+L EA + +G Y + VG + S+K + PP
Sbjct: 3168 KFKITSKHFD-TNLHILNLEASD-VGE-YHCKATNEVGSDTCSCSVK-------FKEPPR 3217
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
F ++L D I + L IV P SVVW G+V
Sbjct: 3218 FVKKLSDTSTLIGDAVELRA-IVEGFQPISVVWLKDRGEV 3256
Score = 92.7 bits (220), Expect = 2e-18
Identities = 69/284 (24%), Positives = 127/284 (44%), Gaps = 23/284 (8%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G Y +A+N GSDT + + A PP F+++L D++ VG + I
Sbjct: 4130 DIGEYQCKATNDVGSDTCVGSIALKA--------PPRFVKKLSDISTVVGKEVQLQTTIE 4181
Query: 133 SSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+ V W++++ ++ E++ + I + G++TC +N G C
Sbjct: 4182 GAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQEC 4241
Query: 192 SAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV 250
A L+VL P ++PE ++ +T T +LEC V G P +WFKD +E+ + +
Sbjct: 4242 FATLSVLEPATIVEKPESIK-----VTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNK 4296
Query: 251 FALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
+ ++ + G YS + VG+ S SL+ + + PP F
Sbjct: 4297 YKISFFNK---VSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTV----PPSF 4349
Query: 311 TRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
TR+L++ + C++ P P SV W+++ ++ +G +
Sbjct: 4350 TRKLKETNGLSGSSVVMECKVYGSP-PISVSWFHEGNEISSGRK 4392
Score = 89.8 bits (213), Expect = 1e-17
Identities = 73/284 (25%), Positives = 128/284 (45%), Gaps = 39/284 (13%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
++G Y+ +N AGS + L V ++P TF++RL D +V+ G+
Sbjct: 3565 ESGDYSCLVTNDAGSASCTTHLFV--------KEPATFVKRLADFSVETGSPIVLEATYT 3616
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
+ V+W ++E + ++ER SI +++C EN G+ C
Sbjct: 3617 GTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICE 3676
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG---- 248
A ++VL P + P +E + A++ E T L+CKV G P + W+K+ ++++
Sbjct: 3677 ALVSVLEPPYFIEP--LEHVEAVIGEPAT--LQCKVDGTPEIRISWYKEHTKLRSAPAYK 3732
Query: 249 -----DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
+V +L N D + +G Y+C+A N +G SS+ + + R
Sbjct: 3733 MQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR--------------- 3777
Query: 304 PEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
+ PP F R+L+D + + P C+I P V WY K+G
Sbjct: 3778 -KLPPFFARKLKDVHETLGFPVAFECRINGSE-PLQVSWY-KDG 3818
Score = 88.2 bits (209), Expect = 4e-17
Identities = 77/280 (27%), Positives = 117/280 (41%), Gaps = 40/280 (14%)
Query: 74 TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIIS 133
+G YT SN AG + RL V ++P FL+RL D +V+ G
Sbjct: 2625 SGEYTCVVSNNAGQASCTTRLFV--------KEPAAFLKRLSDHSVEPGKSIILESTYTG 2676
Query: 134 STECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSA 193
+ VTW ++ + +E+ +IV G+++C EN GR C A
Sbjct: 2677 TLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGA 2736
Query: 194 HLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIK------ 246
++ L P P FV EL L G +VSL+C+V G P + W+K +++
Sbjct: 2737 LVSTLEP-----PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR 2791
Query: 247 ---AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
+V L N + G YTC+A N +G A S + + R
Sbjct: 2792 TYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER--------------- 2836
Query: 304 PEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWY 343
+ PP F R+L+D + P TL+C++ P V WY
Sbjct: 2837 -QLPPSFARQLKDIEQTVGLPVTLTCRLNGSA-PIQVCWY 2874
Score = 87.0 bits (206), Expect = 9e-17
Identities = 61/223 (27%), Positives = 99/223 (44%), Gaps = 24/223 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ-DLTVKVG 122
L + + TG YT +N GSD+ L V+ +PP F+++L+ VK G
Sbjct: 2052 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT--------EPPKFVKKLEASKIVKAG 2103
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
+R +I S E +V W+RNE L +++ + S G + C A
Sbjct: 2104 DSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEA 2163
Query: 183 ENVGGRASCSAHLNVLVPKAYKR-PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
+N G SCS + V P + P VE L+ VSLEC++ G P + W+KD
Sbjct: 2164 QNPAGSTSCSTKVIVKEPPVFSSFPPIVETLK-----NAEVSLECELSGTPPFEVVWYKD 2218
Query: 242 SREIKAGDVFALTAN---------AEDPTSLGTYTCEAVNCMG 275
R++++ + + + D + +G Y C+A N +G
Sbjct: 2219 KRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 2261
Score = 85.0 bits (201), Expect = 4e-16
Identities = 77/289 (26%), Positives = 119/289 (41%), Gaps = 29/289 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +++ + D G YT A+N AGSD R L V ++PP+F++ + L V G
Sbjct: 2522 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV--------QEPPSFVKEPEPLEVLPGK 2573
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F I + KV W+R R L++ +R +I + + G +TC
Sbjct: 2574 NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVS 2633
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G+ASC+ L V P A F++ L E G ++ LE G + W KD
Sbjct: 2634 NNAGQASCTTRLFVKEPAA-----FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDG 2688
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE--GSLKPNSS 300
I + + T+ T E +N R + A R+ G+L
Sbjct: 2689 FNITTSEKCNIV------TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGAL----- 2737
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
+S PP F ELE + + +L CQ+ P +V WY + K+
Sbjct: 2738 -VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTP-EITVSWYKGDTKL 2784
Score = 85.0 bits (201), Expect = 4e-16
Identities = 80/308 (25%), Positives = 124/308 (40%), Gaps = 41/308 (13%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
DR + E L + T +G YT SN AG + L + A P F
Sbjct: 4484 DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKA--------PAKF 4535
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
++RL D +++ G + VTW +N + ++R +I
Sbjct: 4536 VKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSS 4595
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
G++ C EN G+ SCSA + +L P P FV++L + G + SL+C++
Sbjct: 4596 TVEDAGQYNCYIENASGKDSCSAQILILEP-----PYFVKQLEPVKVSVGDSASLQCQLA 4650
Query: 230 GVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
G P + W+K +++ +V L N D G Y C+A N +G +S
Sbjct: 4651 GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAS 4710
Query: 281 SKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSV 340
+ + V +E L PP F+R+L D + P C I P SV
Sbjct: 4711 TFLTV-----QEQKL-----------PPSFSRQLRDVQETVGLPVVFDCAISGSE-PISV 4753
Query: 341 VWYNKEGK 348
WY K+GK
Sbjct: 4754 SWY-KDGK 4760
Score = 84.6 bits (200), Expect = 5e-16
Identities = 71/299 (23%), Positives = 133/299 (44%), Gaps = 25/299 (8%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
++ T+ L ++ DTG Y SN GS + R+ + ++PP+F+
Sbjct: 1665 KYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVAL--------KEPPSFI 1716
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+++++ T + + F + S +TW ++++ L E + V I S
Sbjct: 1717 KKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVD 1776
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVG 230
GR+TC A+N G C A L V P + VE+ +++ +TE+ ++LEC V G
Sbjct: 1777 NGHSGRYTCQAKNESGVERCYAFLLVQEPA-----QIVEKAKSVDVTEKDPMTLECVVAG 1831
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV-HVVGRA 289
P ++W KD ++I F+++ ++ ++ ++V + KV + G +
Sbjct: 1832 TPELKVKWLKDGKQIVPSRYFSMSFE----NNVASFRIQSVMKQDSGQYTFKVENDFGSS 1887
Query: 290 SREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
S + L+ L PP FT++L + + C+ V P S W+ K+GK
Sbjct: 1888 SCDAYLRV----LDQNIPPSFTKKLTKMDKVLGSSIHMECK-VSGSLPISAQWF-KDGK 1940
Score = 83.4 bits (197), Expect = 1e-15
Identities = 72/287 (25%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV+ D+G YT A+N AGSD L V +PP+F+++ + V GT
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTV--------REPPSFVQKPDPMDVLTGT 4455
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F + + V+W++ L+ +R ++ + S G +TC
Sbjct: 4456 NVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVS 4515
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G+ASC+ HL + P +FV+ L E+G + LE G P + W K+
Sbjct: 4516 NEAGKASCTTHLYIKAP-----AKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNG 4570
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ +T + P + V G+ Y+ + AS + S S+ +
Sbjct: 4571 INVTPSQRCNITTTEKSP--ILEIPSSTVEDAGQ-YNC----YIENASGKDSC---SAQI 4620
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
PP F ++LE V + + +L CQ+ P V WY + K+
Sbjct: 4621 LILEPPYFVKQLEPVKVSVGDSASLQCQLAGTP-EIGVSWYKGDTKL 4666
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/232 (25%), Positives = 100/232 (43%), Gaps = 17/232 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + D+G YT +A N+ G+ +++ + + P P+F R+L+D+ VG
Sbjct: 2801 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLP-----PSFARQLKDIEQTVGL 2855
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S +V WYR+ L + E + + G+++C+A
Sbjct: 2856 PVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSAS 2915
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G AS SA L PK K P F ++ + + + EC V G + W KD+
Sbjct: 2916 NPLGTASSSARLTAREPK--KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN 2973
Query: 243 REIKAGDVFALTANAEDP---------TSLGTYTCEAVNCMGRAYSSSKVHV 285
+EI+ G + +T P G YTC+A N +G+ S+++ V
Sbjct: 2974 KEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 3025
Score = 82.6 bits (195), Expect = 2e-15
Identities = 77/324 (23%), Positives = 126/324 (38%), Gaps = 41/324 (12%)
Query: 42 KSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
K R +F T + L + D G Y +A+N GSDT ++
Sbjct: 3158 KDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKF----- 3212
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDG 160
++PP F+++L D + +G + V W ++ ++ E+E I
Sbjct: 3213 ---KEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFID 3269
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQ 219
+ G++ C +N G CSA L VL P + ++PE + +T
Sbjct: 3270 NIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMT-----VTTG 3324
Query: 220 GTVSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
+LEC V G P +WFKD RE+ A V +L + + G Y+ E
Sbjct: 3325 NPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEV 3384
Query: 271 VNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQ 330
N +G++ + VHV R PP F R+L+D + L C+
Sbjct: 3385 KNSVGKSNCTVSVHVSDRI----------------VPPSFIRKLKDVNAILGASVVLECR 3428
Query: 331 IVVPPWPRSVVWYNKEGKVEAGER 354
V P SV W+ ++ +G +
Sbjct: 3429 -VSGSAPISVGWFQDGNEIVSGPK 3451
Score = 81.0 bits (191), Expect = 6e-15
Identities = 77/289 (26%), Positives = 114/289 (39%), Gaps = 25/289 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S DTG+YT A+N AGSD L V ++PP+F + + V G
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV--------QEPPSFEQTPDSVEVLPGM 3514
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F I + KV W++ R L+ E +I + G ++C
Sbjct: 3515 SLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVT 3574
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
N G ASC+ HL V P FV+ L E G+ + LE G P + W KD
Sbjct: 3575 NDAGSASCTTHLFVKEPAT-----FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDE 3629
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
I + ++T E T L E + Y+ + A ++ + +
Sbjct: 3630 YLISQSERCSITM-TEKSTIL-----EILESTIEDYAQYSCLIENEAGQDIC----EALV 3679
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEA 351
S PP F LE I EP TL C++ P R + WY + K+ +
Sbjct: 3680 SVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIR-ISWYKEHTKLRS 3727
Score = 79.4 bits (187), Expect = 2e-14
Identities = 64/226 (28%), Positives = 101/226 (44%), Gaps = 17/226 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G Y +A N+ G +A L V ++ P P+F R+L+D+ VG F I
Sbjct: 4692 DSGEYICKAENSVGEVSASTFLTVQEQKLP-----PSFSRQLRDVQETVGLPVVFDCAIS 4746
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V+WY++ + L ++ V + G+++CTA N G AS S
Sbjct: 4747 GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSS 4806
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVF 251
A L ++ + P F L + G + EC V G + W KDSREI++G +
Sbjct: 4807 ARL--ILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKY 4864
Query: 252 A---------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
LT D G YTC AVN +G+ ++++++ R
Sbjct: 4865 QISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 4910
Score = 79.0 bits (186), Expect = 2e-14
Identities = 63/245 (25%), Positives = 111/245 (45%), Gaps = 24/245 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S D GVY+ +ASN G+D + L + D P F++ L+ + +
Sbjct: 273 LELSNLTIQDRGVYSCKASNKFGADICQAELIII--------DKPHFIKELEPVQSAINK 324
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ ++ + VTW ++ ++L + I + G + CTA
Sbjct: 325 KVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTAS 384
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEEL--RALLTEQGTVSLECKVVGVPTPVLRWFKD 241
N G +SCSA + V P P FV+++ L+ + L CK+ G P + WFK+
Sbjct: 385 NEAGSSSCSATVTVREP-----PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKN 439
Query: 242 SREI-KAGDVFALTANAE---DPTSL-----GTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
++E+ ++ V N+E D T + G+Y+CEAVN +G S+++ + S
Sbjct: 440 NKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI 499
Query: 293 GSLKP 297
+L+P
Sbjct: 500 KTLEP 504
Score = 78.6 bits (185), Expect = 3e-14
Identities = 71/293 (24%), Positives = 117/293 (39%), Gaps = 24/293 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y+ + N+ G V + VS P P+F+R+L+D+ +G
Sbjct: 3367 LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVP-----PSFIRKLKDVNAILGA 3421
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S V W+++ ++ + + G +TC A
Sbjct: 3422 SVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAA 3481
Query: 184 NVGGRASCSAHLNVLVPKAYKR-PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
NV G CSA L V P ++++ P+ VE L + +++ + G P ++WFK S
Sbjct: 3482 NVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGM-----SLTFTSVIRGTPPFKVKWFKGS 3536
Query: 243 REIKAGDVFALTANAED-PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
RE+ G+ + + ED T L + + + YS + G AS ++
Sbjct: 3537 RELVPGE--SCNISLEDFVTELELFEVQPLE--SGDYSCLVTNDAGSAS-------CTTH 3585
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
L + P F + L D V P L P P SV W E + ER
Sbjct: 3586 LFVKEPATFVKRLADFSVETGSPIVLEATYTGTP-PISVSWIKDEYLISQSER 3637
Score = 78.6 bits (185), Expect = 3e-14
Identities = 68/234 (29%), Positives = 94/234 (40%), Gaps = 20/234 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV GD+G YT A N G D+ +L + PP+F +RL + TV+
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLI-----PPSFTKRLSE-TVEETE 4928
Query: 124 RTRFLVE--IISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
F +E + S V WY+N + I + G +TC
Sbjct: 4929 GNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCK 4988
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFK 240
N G A C++ + + PK K P F + L + +G V L C V G ++W K
Sbjct: 4989 VSNDAGSALCTSSIVIKEPK--KPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLK 5046
Query: 241 DSREIKAGD----VFAL-TANAE----DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
REIK D FA TA E G Y C+A N G + SKV +
Sbjct: 5047 AGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 5100
Score = 78.2 bits (184), Expect = 4e-14
Identities = 74/295 (25%), Positives = 122/295 (41%), Gaps = 41/295 (13%)
Query: 71 TGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVE 130
T D G Y +A N GSDT +++ ++PP F+ +L LTV G
Sbjct: 2246 TSDIGEYHCKAQNEVGSDTCVCTVKL--------KEPPRFVSKLNSLTVVAGEPAELQAS 2297
Query: 131 IISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRA 189
I + V W + + ++ E+E + I + G++ C +N GG
Sbjct: 2298 IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMR 2357
Query: 190 SCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG 248
A L VL P VE+ + G T +LECKV G P + W+KD + + +
Sbjct: 2358 ENMATLMVLEPAV-----IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSS 2412
Query: 249 D---------VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNS 299
+ +L + + GTYT + N +G++ ++ V V RA
Sbjct: 2413 QKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA---------- 2462
Query: 300 SGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
PP FTR L++ + L C+ V P SV W++++ K+ +G +
Sbjct: 2463 ------VPPSFTRRLKNTGGVLGASCILECK-VAGSSPISVAWFHEKTKIVSGAK 2510
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/220 (25%), Positives = 95/220 (43%), Gaps = 23/220 (10%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+S AR ++G Y +A N AG+ + + L+V ++PPTF+R L+ + V +
Sbjct: 1586 ISGARVENSGTYVCEARNDAGTASCSIELKV--------KEPPTFIRELKPVEVVKYSDV 1637
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
E+ + +VTW +N R + +++ ++ S F G + C N
Sbjct: 1638 ELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNE 1697
Query: 186 GGRASCSAHLNVLVPKAYKRPEFVEELRALLTE-QGTVSLECKVVGVPTPVLRWFKDSRE 244
GG SCS + + P P F++++ T + + + + V G P + W KD +
Sbjct: 1698 GGSCSCSTRVALKEP-----PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQI 1752
Query: 245 IKAGD---------VFALTANAEDPTSLGTYTCEAVNCMG 275
+ D V L + D G YTC+A N G
Sbjct: 1753 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 1792
Score = 77.8 bits (183), Expect = 5e-14
Identities = 58/222 (26%), Positives = 92/222 (41%), Gaps = 21/222 (9%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISS 134
G Y ASN G+ ++ +L +S E P P F + + + +G F + +
Sbjct: 3849 GQYNCSASNPLGTASSSAKLILSEHEVP-----PFFDLKPVSVDLALGESGTFKCHVTGT 3903
Query: 135 TECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAH 194
K+TW ++ R + + + G++TC A N+ G+ SCSA
Sbjct: 3904 APIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQ 3963
Query: 195 LNVLVPKAYKRPEFVEELR--ALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF- 251
L V P P F+++L ++ + ECK+ G P + W+KD EI+ F
Sbjct: 3964 LGVQEP-----PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFR 4018
Query: 252 --------ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L + G YTCEA N G A SS+ + V
Sbjct: 4019 MSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 4060
Score = 77.0 bits (181), Expect = 9e-14
Identities = 68/235 (28%), Positives = 101/235 (42%), Gaps = 24/235 (10%)
Query: 62 VRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKV 121
V L V+ DT YT + SN AG D L V +E PS P + + D TV+
Sbjct: 1957 VSLEVNNLELEDTANYTCKVSNVAGDDACSGILTV--KEPPSFLVKPGRQQAIPDSTVE- 2013
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
F + + K+ W++++ L+ + I +GS G++TC
Sbjct: 2014 -----FKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCH 2068
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVS-LECKVVGVPTPVLRWF 239
N G SC+ L V P P+FV++L A + + G S LECK+ G P + WF
Sbjct: 2069 VTNDVGSDSCTTMLLVTEP-----PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWF 2123
Query: 240 KDSREIKAGDVFALT---------ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
++ E+ A D + +T N G + CEA N G S+KV V
Sbjct: 2124 RNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 2178
Score = 76.2 bits (179), Expect = 2e-13
Identities = 69/265 (26%), Positives = 103/265 (38%), Gaps = 22/265 (8%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
DD T E L +S G Y QA N AG L V ++P T
Sbjct: 1194 DDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV--------KEPAT 1245
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXX 169
+ V G V+ + E W+++ + L + I +
Sbjct: 1246 ITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIIS 1305
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKV 228
G +T +N GR+SC A +NVL P F ++L+ + + +G+ + LEC V
Sbjct: 1306 TEKKDSGEYTFEVQNDVGRSSCKARINVL--DLIIPPSFTKKLKKMDSIKGSFIDLECIV 1363
Query: 229 VGVPTPVLRWFKDSREIKAGDVFAL-----TANAE----DPTSLGTYTCEAVNCMGRAYS 279
G ++WFKD +EI A + + TA E + T GTYTC A N G
Sbjct: 1364 AGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQC 1423
Query: 280 SSKVHVVGRASREGSLKPNSSGLSP 304
S H+ + KP S ++P
Sbjct: 1424 SG--HLTVKEPPYFVEKPQSQDVNP 1446
Score = 74.5 bits (175), Expect = 5e-13
Identities = 69/273 (25%), Positives = 113/273 (41%), Gaps = 26/273 (9%)
Query: 53 FVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAG--SDTARVRLE---------VSAEES 101
F T+ +L ++ A D G YT A+NA G S TA + LE + E
Sbjct: 55 FRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIE 114
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
+ P R+++ L V +G +F EI S+ + W++ R + E+++ SI
Sbjct: 115 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY 174
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG- 220
G +TC A N G SC+A L V +AY P F+ ++L T G
Sbjct: 175 ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT--VTEAYP-PTFLSRPKSLTTFVGK 231
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEA 270
C V G P W KD + + + ++AE+ L G Y+C+A
Sbjct: 232 AAKFICTVTGTPVIETIWQKDGAALSPSPNWRI-SDAENKHILELSNLTIQDRGVYSCKA 290
Query: 271 VNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
N G +++ ++ + L+P S ++
Sbjct: 291 SNKFGADICQAELIIIDKPHFIKELEPVQSAIN 323
Score = 74.1 bits (174), Expect = 7e-13
Identities = 58/232 (25%), Positives = 93/232 (40%), Gaps = 20/232 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G YT Q N G + ++VS P P+F RRL++ +G
Sbjct: 2426 LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVP-----PSFTRRLKNTGGVLGA 2480
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
++ S+ V W+ + +++ + + G +TC A
Sbjct: 2481 SCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAA 2540
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
NV G C A L V P P FV+E L G V+ + G P + WF+ +
Sbjct: 2541 NVAGSDECRAVLTVQEP-----PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 2595
Query: 243 REIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
RE+ GD ++ AE D + G YTC N G+A ++++ V
Sbjct: 2596 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 2647
Score = 73.7 bits (173), Expect = 9e-13
Identities = 65/293 (22%), Positives = 116/293 (39%), Gaps = 20/293 (6%)
Query: 62 VRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKV 121
V L + D G Y + +N GS R+ + +PP+F+++++ +
Sbjct: 1113 VSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL--------REPPSFIKKIESTSSLR 1164
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
G F + S VTW ++ + E + + + + + G++ C
Sbjct: 1165 GGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 1224
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A+N G CSA L+V P E + +T+ +L+ K G +WFKD
Sbjct: 1225 AKNDAGIQRCSALLSVKEPATITE----EAVSIDVTQGDPATLQVKFSGTKEITAKWFKD 1280
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
+E+ G + ++ D S+ G Y+ + VGR+ S K +
Sbjct: 1281 GQELTLGSKYKISVT--DTVSILKIISTEKKDSGE-YTFEVQNDVGRS----SCKARINV 1333
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
L PP FT++L+ L C IV P S+ W+ + ++ A E+
Sbjct: 1334 LDLIIPPSFTKKLKKMDSIKGSFIDLEC-IVAGSHPISIQWFKDDQEISASEK 1385
Score = 72.9 bits (171), Expect = 2e-12
Identities = 69/249 (27%), Positives = 96/249 (38%), Gaps = 30/249 (12%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
DR+ G L + D G +T +A+N+ GS + L V ++PP+F
Sbjct: 822 DRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV--------QEPPSF 873
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ + V G+ ST + W++ + L+ I ++
Sbjct: 874 VTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLV 933
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKV 228
G +TC NV G CSA+L V P FVE+L LL + L CKV
Sbjct: 934 KTSDSGTYTCKVSNVAGGVECSANLFVKEPAT-----FVEKLEPSQLLKKGDATQLACKV 988
Query: 229 VGVPTPVLRWFKDSREIKAGD-----------VFALT-ANAEDPTSLGTYTCEAVNCMGR 276
G P + WF + REIK V LT ED G Y CEA N G
Sbjct: 989 TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDS---GEYMCEAQNEAGS 1045
Query: 277 AYSSSKVHV 285
+ SS V V
Sbjct: 1046 DHCSSIVIV 1054
Score = 72.5 bits (170), Expect = 2e-12
Identities = 58/239 (24%), Positives = 105/239 (43%), Gaps = 24/239 (10%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T+EA L + +T D+G YT + SN AG L V ++P TF+ +L+
Sbjct: 920 TKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV--------KEPATFVEKLE 971
Query: 116 -DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+K G T+ ++ + K+TW+ N+R + E+ + + S
Sbjct: 972 PSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIED 1031
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPT 233
G + C A+N G CS+ +++ K + P F +E + + + ++ V L +V G P
Sbjct: 1032 SGEYMCEAQNEAGSDHCSS---IVIVK--ESPYFTKEFKPIEVLKEYDVMLLAEVAGTPP 1086
Query: 234 PVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ WFKD+ +++G + +L G Y C N +G + S++V
Sbjct: 1087 FEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARV 1145
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/224 (24%), Positives = 97/224 (43%), Gaps = 24/224 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKV-G 122
L + A+ D+G Y ASN AGS + + V +PP+F++++ + + G
Sbjct: 366 LEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV--------REPPSFVKKVDPSYLMLPG 417
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R ++ S +VTW++N + L E+ V + S G ++C A
Sbjct: 418 ESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEA 477
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKD 241
N G SCS + + P P F++ L +GT +L +C+V G + WFKD
Sbjct: 478 VNDVGSDSCSTEIVIKEP-----PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKD 532
Query: 242 SREIKAGDVFALTANAE---------DPTSLGTYTCEAVNCMGR 276
++I++ + L + + +G Y C N +G+
Sbjct: 533 KKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 576
Score = 71.7 bits (168), Expect = 4e-12
Identities = 61/221 (27%), Positives = 91/221 (41%), Gaps = 20/221 (9%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISS 134
G YT A N AGS T+ L V ++P + R + + V G + +
Sbjct: 657 GKYTCLAENEAGSQTSVGELIV--------KEPAKIIERAELIQVTAGDPATLEYTVAGT 708
Query: 135 TECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAH 194
E K WY++ R L+ +++ I + G++T N G +SC
Sbjct: 709 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 768
Query: 195 LNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
VL P F + LR + GT L+CK+ G + WFKD +EI A D + +
Sbjct: 769 FTVLDRDI--APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRI 826
Query: 254 -----TANAE----DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
TA+ E D G +TC A N +G SS + V
Sbjct: 827 AFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 867
Score = 71.7 bits (168), Expect = 4e-12
Identities = 69/292 (23%), Positives = 112/292 (38%), Gaps = 24/292 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S D+G YT A+N AG + L V ++PP F+ + Q V T
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV--------KEPPYFVEKPQSQDVNPNT 1448
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R + + + + W+++ + L S+ +D + G + C
Sbjct: 1449 RVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS 1508
Query: 184 NVGGRASCSAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A+ A L V P + K+P V LR Q T + EC++ G P + W+ D
Sbjct: 1509 NDVGTATSKATLFVKEPPQFIKKPSPVLVLR---NGQST-TFECQITGTPKIRVSWYLDG 1564
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
EI A ++ L T+ G +S +V A + S L
Sbjct: 1565 NEITAIQKHGISFI----DGLATFQIS-----GARVENSGTYVC-EARNDAGTASCSIEL 1614
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ PP F REL+ V L C++ P P V W ++ + ++
Sbjct: 1615 KVKEPPTFIRELKPVEVVKYSDVELECEVTGTP-PFEVTWLKNNREIRSSKK 1665
Score = 71.3 bits (167), Expect = 5e-12
Identities = 73/296 (24%), Positives = 126/296 (42%), Gaps = 26/296 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ D G Y+ +A N+ G+ + L + A + P P F R+L+D+ +G
Sbjct: 3742 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLP-----PFFARKLKDVHETLGF 3796
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F I S +V+WY++ L + + + G++ C+A
Sbjct: 3797 PVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSAS 3856
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVE----ELRALLTEQGTVSLECKVVGVPTPVLRWF 239
N G AS SA L+ ++ P F + + L E GT +C V G + W
Sbjct: 3857 NPLGTASSSAK---LILSEHEVPPFFDLKPVSVDLALGESGT--FKCHVTGTAPIKITWA 3911
Query: 240 KDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNS 299
KD+REI+ G + +T E+ +L T G+ Y+ ++ G+ S S
Sbjct: 3912 KDNREIRPGGNYKMTL-VENTATL-TVLKVGKGDAGQ-YTCYASNIAGKDS-------CS 3961
Query: 300 SGLSPEPPPIFTRELEDQYVRICEPFT-LSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ L + PP F ++LE + + FT C+I P V+WY E +++ +
Sbjct: 3962 AQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSP-EIKVLWYKDETEIQESSK 4016
Score = 71.3 bits (167), Expect = 5e-12
Identities = 56/240 (23%), Positives = 98/240 (40%), Gaps = 21/240 (8%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
++T E + L + ++ D G Y NA+G D+ ++ + +PP F+++
Sbjct: 4581 ITTTEKSPI-LEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL--------EPPYFVKQ 4631
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+ + V VG ++ + E V+WY+ + +L + +
Sbjct: 4632 LEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDIN 4691
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVP 232
G + C AEN G S S L V K P F +LR + G V +C + G
Sbjct: 4692 DSGEYICKAENSVGEVSASTFLTVQEQKL--PPSFSRQLRDVQETVGLPVVFDCAISGSE 4749
Query: 233 TPVLRWFKDSREIK---------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ W+KD + +K + L D + G Y+C A N +G A SS+++
Sbjct: 4750 PISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809
Score = 70.5 bits (165), Expect = 8e-12
Identities = 72/294 (24%), Positives = 118/294 (40%), Gaps = 41/294 (13%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISS 134
G Y+ A+N GS ++ RL ++ G++PP F RL + VG F + +
Sbjct: 4790 GQYSCTATNPIGSASSSARLILT-----EGKNPPFFDIRLAPVDAVVGESADFECHVTGT 4844
Query: 135 TECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAH 194
KV+W ++ R + + I + G++TC A N G+ SC+A
Sbjct: 4845 QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQ 4904
Query: 195 LNV---LVPKAYKR--PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKA-- 247
LN+ L+P ++ + E VEE TE + LE +V G + W+K++ EI+
Sbjct: 4905 LNIKERLIPPSFTKRLSETVEE-----TEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTS 4959
Query: 248 -------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
+ L G YTC+ N G A +S + +
Sbjct: 4960 NCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK-------------- 5005
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
P+ PP+F + L V E LSC V P + W +++ +R
Sbjct: 5006 --EPKKPPVFDQHLTPVTVSEGEYVQLSCH-VQGSEPIRIQWLKAGREIKPSDR 5056
Score = 68.1 bits (159), Expect = 4e-11
Identities = 53/214 (24%), Positives = 90/214 (42%), Gaps = 24/214 (11%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT +A NAAGS ++ L+V ++PP F ++ + G E+
Sbjct: 4037 DSGDYTCEAHNAAGSASSSTSLKV--------KEPPIFRKKPHPIETLKGADVHLECELQ 4088
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
+ V+WY+++R L ++ I+ + G + C A N G +C
Sbjct: 4089 GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCV 4148
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREI------ 245
+ + P P FV++L + T G V L+ + G + WFKD EI
Sbjct: 4149 GSIALKAP-----PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDN 4203
Query: 246 ----KAGDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ ++ L + +P + G YTC+ N G
Sbjct: 4204 IWISYSENIATLQFSRVEPANAGKYTCQIKNDAG 4237
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/251 (23%), Positives = 104/251 (41%), Gaps = 14/251 (5%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFC 164
++PPTF++++ DL G + S VTW + + + E ++ +
Sbjct: 586 KEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 645
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQGTVS 223
G++TC AEN G + L V P K +R E ++ +T +
Sbjct: 646 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ-----VTAGDPAT 700
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
LE V G P +W+KD R + A + ++ + L Y+ E ++ G+ Y+
Sbjct: 701 LEYTVAGTPELKPKWYKDGRPLVASKKYRISFK-NNVAQLKFYSAE-LHDSGQ-YTFEIS 757
Query: 284 HVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWY 343
+ VG +S E + + L + P FT+ L + + L C+I P V W+
Sbjct: 758 NEVGSSSCETTF----TVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKI-AGSLPMRVSWF 812
Query: 344 NKEGKVEAGER 354
++ A +R
Sbjct: 813 KDGKEIAASDR 823
Score = 64.5 bits (150), Expect = 5e-10
Identities = 60/232 (25%), Positives = 94/232 (40%), Gaps = 21/232 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G YT +ASN GS + L V+ PPTFL R + LT VG
Sbjct: 178 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY------PPTFLSRPKSLTTFVGK 231
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+F+ + + + W ++ L + I + G ++C A
Sbjct: 232 AAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKAS 291
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTE-QGTVSLECKVVGVPTPVLRWFKDS 242
N G C A L ++ +P F++EL + + V LEC+V + W KD
Sbjct: 292 NKFGADICQAELIII-----DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDG 346
Query: 243 REIKAGDVFAL-----TANAEDPTS----LGTYTCEAVNCMGRAYSSSKVHV 285
+++ G + + A E P + GTY C A N G + S+ V V
Sbjct: 347 QKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398
Score = 63.7 bits (148), Expect = 9e-10
Identities = 39/184 (21%), Positives = 82/184 (44%), Gaps = 14/184 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ + D+G Y+ +A N GSD+ + + ++PP+F++ L+ + GT
Sbjct: 460 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI--------KEPPSFIKTLEPADIVRGT 511
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E+ + +++W+++++++ +++ + S C G + C
Sbjct: 512 NALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVA 571
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G+ C A + P P FV+++ L+ G TV+L+ V G + W K
Sbjct: 572 NEVGKCGCMATHLLKEP-----PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQ 626
Query: 243 REIK 246
I+
Sbjct: 627 EVIR 630
Score = 62.5 bits (145), Expect = 2e-09
Identities = 56/232 (24%), Positives = 86/232 (37%), Gaps = 20/232 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L S + G YT Q N AG L V +P T + + + + V G
Sbjct: 4215 LQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL--------EPATIVEKPESIKVTTGD 4266
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + E W+++ + L + I G ++ +
Sbjct: 4267 TCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQ 4326
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
N G+ SC+A L V P F +L+ G+ V +ECKV G P + WF +
Sbjct: 4327 NPVGKDSCTASLQV--SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEG 4384
Query: 243 REIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
EI +G + ALT N + + G YTC A N G S+ + V
Sbjct: 4385 NEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 4436
Score = 60.1 bits (139), Expect = 1e-08
Identities = 61/246 (24%), Positives = 98/246 (39%), Gaps = 20/246 (8%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
+L +A D+G YT + SN GS + V + P F + L+++ V
Sbjct: 738 QLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIA-----PFFTKPLRNVDSVVN 792
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R +I S +V+W+++ + + ++R I G +TC A
Sbjct: 793 GTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRA 852
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKD 241
N G S L V P P FV + + G+ V L+ G +RWFK
Sbjct: 853 TNSVGSKDSSGALIVQEP-----PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKG 907
Query: 242 SREIKAGDVFALTANA-EDPTSL--------GTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
++E+ +G +T A E L GTYTC+ N G S+ + V A+
Sbjct: 908 NKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFV 967
Query: 293 GSLKPN 298
L+P+
Sbjct: 968 EKLEPS 973
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/222 (22%), Positives = 90/222 (40%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + G +G YT QA N +G + L V ++P + + + + V
Sbjct: 1770 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLV--------QEPAQIVEKAKSVDVTEKD 1821
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + E KV W ++ ++++ + S+ + + G++T E
Sbjct: 1822 PMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVE 1881
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
N G +SC A+L VL P F ++L + G+ + +ECKV G +WFKD
Sbjct: 1882 NDFGSSSCDAYLRVLDQNI--PPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDG 1939
Query: 243 REIKAGDVF---------ALTANAEDPTSLGTYTCEAVNCMG 275
+EI + +L N + YTC+ N G
Sbjct: 1940 KEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAG 1981
Score = 58.0 bits (134), Expect = 5e-08
Identities = 60/250 (24%), Positives = 95/250 (38%), Gaps = 26/250 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L V A D G+YT + SN AGS + + + P P F + L +TV G
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKP-----PVFDQHLTPVTVSEGE 5026
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + S ++ W + R + ++R S G + C A
Sbjct: 5027 YVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKAS 5086
Query: 184 NVGGRASCSAHLNV-----LVPKAYK-----RPEFVEELRAL-LTEQGTVSLECKVVGVP 232
NV G + + + + + P K R FV E +++ + E+ T + KV G P
Sbjct: 5087 NVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 5146
Query: 233 TPVLRWFKDS-REI---------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK 282
P ++W K R++ + GD L T G Y C A N G S+
Sbjct: 5147 IPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVN 5206
Query: 283 VHVVGRASRE 292
+ V R +E
Sbjct: 5207 LQVDERKKQE 5216
Score = 51.6 bits (118), Expect = 4e-06
Identities = 63/286 (22%), Positives = 106/286 (37%), Gaps = 25/286 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT++ A D+G Y +A N G + L V A PP F ++ + G+
Sbjct: 3087 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKA--------PPVFTQKPSPVGALKGS 3138
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
EI + +V W ++ +++ +++ I G + C A
Sbjct: 3139 DVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKAT 3198
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G +CS + P P FV++L T G V L V G + W KD
Sbjct: 3199 NEVGSDTCSCSVKFKEP-----PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKD- 3252
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
G+V + N T + A +G +S+ + + + ++ S+ L
Sbjct: 3253 ----RGEVIRESEN----TRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVL 3304
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ P + E V PF L C + P S W+ K+G+
Sbjct: 3305 TVLEPARIIEKPEPMTVTTGNPFALECVVTGTP-ELSAKWF-KDGR 3348
Score = 44.0 bits (99), Expect = 8e-04
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 10/174 (5%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVS-------AEESPS 103
DR + +G L + D+G Y +ASN AGSDT + ++ + A + +
Sbjct: 5055 DRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAA 5114
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNE-RRLLEAERVSIVRDGSF 162
+ F+ Q + V T F+ ++ V W + + R+L + RV I + G
Sbjct: 5115 VDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDE 5174
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
G + C A N G +++N+ V + K+ + +LRA+L
Sbjct: 5175 AKLEIRDTTKTDSGLYRCVAFNEHG--EIESNVNLQVDERKKQEKIEGDLRAML 5226
Score = 39.1 bits (87), Expect = 0.023
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 12/98 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
+LT++ R D G YT + + LE SAE E P F +R+Q++ V
Sbjct: 5465 KLTIADVRAEDQGQYTCKYED----------LETSAELRIEAE-PIQFTKRIQNIVVSEH 5513
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
F E+ S + VTWY+ L E+++ + DG
Sbjct: 5514 QSATFECEV-SFDDAIVTWYKGPTELTESQKYNFRNDG 5550
Score = 35.5 bits (78), Expect = 0.28
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 11/145 (7%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRNERRLLEAERVSIVRDGS 161
S +P T ++ +++ TV F ++I I+ E K++WY+ +L +++ I DG
Sbjct: 5316 SQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 5375
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
G + V G SA L V+ P A++R L+ + ++G
Sbjct: 5376 RHTLRVKNCQLKDQGNYRL----VCGPHIASAKLTVIEP-AWER-----HLQDVTLKEGQ 5425
Query: 222 VSLECKVVGVPTPVLRWFKDSREIK 246
VP WF++ R +K
Sbjct: 5426 TCTMTVQFSVPNVKSEWFRNGRILK 5450
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 103 bits (248), Expect = 7e-22
Identities = 84/288 (29%), Positives = 131/288 (45%), Gaps = 26/288 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ-DLTVKVG 122
LTV GD G YT ASN AG D+ L V ++PP F+++L+ VK
Sbjct: 8196 LTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGV--------QEPPRFIKKLEPSRIVKQD 8247
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
TR+ +I S E KV WY++E + E+ + + S G +TC A
Sbjct: 8248 EFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEA 8307
Query: 183 ENVGGRASCSAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
N G AS S L V P + K+P +E L+ V LEC++ G P + W+KD
Sbjct: 8308 HNAAGSASSSTSLKVKEPPIFRKKPHPIETLKG-----ADVHLECELQGTPPFHVSWYKD 8362
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
RE+++G + + + TS+ +A + +G Y + VG + GS
Sbjct: 8363 KRELRSGKKYKIMSE-NFLTSIHILNVDAAD-IGE-YQCKATNDVGSDTCVGS------- 8412
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
++ + PP F ++L D + + L I P SVVW+ +G++
Sbjct: 8413 IALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAE-PISVVWFKDKGEI 8459
Score = 95.1 bits (226), Expect = 3e-19
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 26/280 (9%)
Query: 72 GDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV-KVGTRTRFLVE 130
GD+G YT QA+N G D +L V ++PP F+++L+ V K G + +
Sbjct: 7263 GDSGQYTCQATNDVGKDMCSAQLSV--------KEPPKFVKKLEASKVAKQGESIQLECK 7314
Query: 131 IISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRAS 190
I S E KV+W+RN+ L E+ + ++ S G + C A N G AS
Sbjct: 7315 ISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDAS 7374
Query: 191 CSAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD 249
CS L V P + ++P V L+ V L+C++ G P + W KD ++++
Sbjct: 7375 CSTALTVKAPPVFTQKPSPVGALKG-----SDVILQCEISGTPPFEVVWVKDRKQVRNSK 7429
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
F +T+ D TSL EA + +G Y + VG + S+K + PP
Sbjct: 7430 KFKITSKHFD-TSLHILNLEASD-VGE-YHCKATNEVGSDTCSCSVK-------FKEPPR 7479
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
F ++L D I + L IV P SVVW G+V
Sbjct: 7480 FVKKLSDTSTLIGDAVELRA-IVEGFQPISVVWLKDRGEV 7518
Score = 92.7 bits (220), Expect = 2e-18
Identities = 69/284 (24%), Positives = 127/284 (44%), Gaps = 23/284 (8%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G Y +A+N GSDT + + A PP F+++L D++ VG + I
Sbjct: 8392 DIGEYQCKATNDVGSDTCVGSIALKA--------PPRFVKKLSDISTVVGKEVQLQTTIE 8443
Query: 133 SSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+ V W++++ ++ E++ + I + G++TC +N G C
Sbjct: 8444 GAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQEC 8503
Query: 192 SAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV 250
A L+VL P ++PE ++ +T T +LEC V G P +WFKD +E+ + +
Sbjct: 8504 FATLSVLEPATIVEKPESIK-----VTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNK 8558
Query: 251 FALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
+ ++ + G YS + VG+ S SL+ + + PP F
Sbjct: 8559 YKISFFNK---VSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTV----PPSF 8611
Query: 311 TRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
TR+L++ + C++ P P SV W+++ ++ +G +
Sbjct: 8612 TRKLKETNGLSGSSVVMECKVYGSP-PISVSWFHEGNEISSGRK 8654
Score = 91.5 bits (217), Expect = 4e-18
Identities = 77/284 (27%), Positives = 131/284 (46%), Gaps = 39/284 (13%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
++G Y+ +N AGS + L V ++P TF++RL D +V+ G+
Sbjct: 7827 ESGDYSCLVTNDAGSASCTTHLFV--------KEPATFVKRLADFSVETGSPIVLEATYT 7878
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
+ V+W ++E + ++ER SI +++C EN G+ C
Sbjct: 7879 GTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICE 7938
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKA----- 247
A ++VL P + P +E + A++ E T L+CKV G P + W+K+ ++++
Sbjct: 7939 ALVSVLEPPYFIEP--LEHVEAVIGEPAT--LQCKVDGTPEIRISWYKEHTKLRSAPAYK 7994
Query: 248 ----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
+V +L N D + +G Y+C+A N +G A +SS V V+ +E L
Sbjct: 7995 MQFKNNVASLVINKVDHSDVGEYSCKADNSVG-AVASSAVLVI----KERKL-------- 8041
Query: 304 PEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
PP F R+L+D + + P C+I P V WY K+G
Sbjct: 8042 ---PPFFARKLKDVHETLGFPVAFECRINGSE-PLQVSWY-KDG 8080
Score = 88.2 bits (209), Expect = 4e-17
Identities = 77/280 (27%), Positives = 117/280 (41%), Gaps = 40/280 (14%)
Query: 74 TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIIS 133
+G YT SN AG + RL V ++P FL+RL D +V+ G
Sbjct: 6887 SGEYTCVVSNNAGQASCTTRLFV--------KEPAAFLKRLSDHSVEPGKSIILESTYTG 6938
Query: 134 STECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSA 193
+ VTW ++ + +E+ +IV G+++C EN GR C A
Sbjct: 6939 TLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGA 6998
Query: 194 HLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIK------ 246
++ L P P FV EL L G +VSL+C+V G P + W+K +++
Sbjct: 6999 LVSTLEP-----PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR 7053
Query: 247 ---AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
+V L N + G YTC+A N +G A S + + R
Sbjct: 7054 TYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER--------------- 7098
Query: 304 PEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWY 343
+ PP F R+L+D + P TL+C++ P V WY
Sbjct: 7099 -QLPPSFARQLKDIEQTVGLPVTLTCRLNGSA-PIQVCWY 7136
Score = 87.0 bits (206), Expect = 9e-17
Identities = 61/223 (27%), Positives = 99/223 (44%), Gaps = 24/223 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ-DLTVKVG 122
L + + TG YT +N GSD+ L V+ +PP F+++L+ VK G
Sbjct: 6314 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT--------EPPKFVKKLEASKIVKAG 6365
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
+R +I S E +V W+RNE L +++ + S G + C A
Sbjct: 6366 DSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEA 6425
Query: 183 ENVGGRASCSAHLNVLVPKAYKR-PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
+N G SCS + V P + P VE L+ VSLEC++ G P + W+KD
Sbjct: 6426 QNPAGSTSCSTKVIVKEPPVFSSFPPIVETLK-----NAEVSLECELSGTPPFEVVWYKD 6480
Query: 242 SREIKAGDVFALTAN---------AEDPTSLGTYTCEAVNCMG 275
R++++ + + + D + +G Y C+A N +G
Sbjct: 6481 KRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 6523
Score = 85.8 bits (203), Expect = 2e-16
Identities = 80/308 (25%), Positives = 124/308 (40%), Gaps = 41/308 (13%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
DR + E L + T +G YT SN AG + L + A P F
Sbjct: 8746 DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKA--------PAKF 8797
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
++RL D +++ G + VTW +N + ++R +I
Sbjct: 8798 VKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSS 8857
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
G++ C EN G+ SCSA + +L P P FV++L + G + SL+C++
Sbjct: 8858 TVEDAGQYNCYIENASGKDSCSAQILILEP-----PYFVKQLEPVKVSVGDSASLQCQLA 8912
Query: 230 GVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
G P + W+K +++ +V L N D G Y C+A N +G +S
Sbjct: 8913 GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAS 8972
Query: 281 SKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSV 340
+ + V +E L PP F+R+L D + P C I P SV
Sbjct: 8973 TFLTV-----QEQKL-----------PPSFSRQLRDVQETVGLPVVFDCAISGSE-PISV 9015
Query: 341 VWYNKEGK 348
WY K+GK
Sbjct: 9016 SWY-KDGK 9022
Score = 85.0 bits (201), Expect = 4e-16
Identities = 77/289 (26%), Positives = 119/289 (41%), Gaps = 29/289 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +++ + D G YT A+N AGSD R L V ++PP+F++ + L V G
Sbjct: 6784 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV--------QEPPSFVKEPEPLEVLPGK 6835
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F I + KV W+R R L++ +R +I + + G +TC
Sbjct: 6836 NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVS 6895
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G+ASC+ L V P A F++ L E G ++ LE G + W KD
Sbjct: 6896 NNAGQASCTTRLFVKEPAA-----FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDG 6950
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE--GSLKPNSS 300
I + + T+ T E +N R + A R+ G+L
Sbjct: 6951 FNITTSEKCNIV------TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGAL----- 6999
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
+S PP F ELE + + +L CQ+ P +V WY + K+
Sbjct: 7000 -VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTP-EITVSWYKGDTKL 7046
Score = 84.6 bits (200), Expect = 5e-16
Identities = 71/299 (23%), Positives = 133/299 (44%), Gaps = 25/299 (8%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
++ T+ L ++ DTG Y SN GS + R+ + ++PP+F+
Sbjct: 5927 KYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVAL--------KEPPSFI 5978
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+++++ T + + F + S +TW ++++ L E + V I S
Sbjct: 5979 KKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVD 6038
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVG 230
GR+TC A+N G C A L V P + VE+ +++ +TE+ ++LEC V G
Sbjct: 6039 NGHSGRYTCQAKNESGVERCYAFLLVQEPA-----QIVEKAKSVDVTEKDPMTLECVVAG 6093
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV-HVVGRA 289
P ++W KD ++I F+++ ++ ++ ++V + KV + G +
Sbjct: 6094 TPELKVKWLKDGKQIVPSRYFSMSFE----NNVASFRIQSVMKQDSGQYTFKVENDFGSS 6149
Query: 290 SREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
S + L+ L PP FT++L + + C+ V P S W+ K+GK
Sbjct: 6150 SCDAYLRV----LDQNIPPSFTKKLTKMDKVLGSSIHMECK-VSGSLPISAQWF-KDGK 6202
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/232 (25%), Positives = 100/232 (43%), Gaps = 17/232 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + D+G YT +A N+ G+ +++ + + P P+F R+L+D+ VG
Sbjct: 7063 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLP-----PSFARQLKDIEQTVGL 7117
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S +V WYR+ L + E + + G+++C+A
Sbjct: 7118 PVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSAS 7177
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G AS SA L PK K P F ++ + + + EC V G + W KD+
Sbjct: 7178 NPLGTASSSARLTAREPK--KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN 7235
Query: 243 REIKAGDVFALTANAEDP---------TSLGTYTCEAVNCMGRAYSSSKVHV 285
+EI+ G + +T P G YTC+A N +G+ S+++ V
Sbjct: 7236 KEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 7287
Score = 83.0 bits (196), Expect = 1e-15
Identities = 74/296 (25%), Positives = 120/296 (40%), Gaps = 43/296 (14%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV+ D+G YT A+N AGSD L V +PP+F+++ + V GT
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTV--------REPPSFVQKPDPMDVLTGT 8717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F + + V+W++ L+ +R ++ + S G +TC
Sbjct: 8718 NVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVS 8777
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G+ASC+ HL + P +FV+ L E+G + LE G P + W K+
Sbjct: 8778 NEAGKASCTTHLYIKAP-----AKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNG 8832
Query: 243 REIKAGDVFALT-----ANAEDPTS----LGTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
+ +T A E P+S G Y C N G+ S+++ ++
Sbjct: 8833 INVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL------- 8885
Query: 294 SLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
PP F ++LE V + + +L CQ+ P V WY + K+
Sbjct: 8886 ------------EPPYFVKQLEPVKVSVGDSASLQCQLAGTP-EIGVSWYKGDTKL 8928
Score = 82.2 bits (194), Expect = 3e-15
Identities = 77/324 (23%), Positives = 126/324 (38%), Gaps = 41/324 (12%)
Query: 42 KSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
K R +F T + L + D G Y +A+N GSDT ++
Sbjct: 7420 KDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKF----- 7474
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDG 160
++PP F+++L D + +G + V W ++ ++ E+E I
Sbjct: 7475 ---KEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFID 7531
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQ 219
+ G++ C +N G CSA L VL P + ++PE + +T
Sbjct: 7532 NIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMT-----VTTG 7586
Query: 220 GTVSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
+LEC V G P +WFKD RE+ A V +L + + G Y+ E
Sbjct: 7587 NPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEV 7646
Query: 271 VNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQ 330
N +G++ + VHV R PP F R+L+D + L C+
Sbjct: 7647 KNSVGKSNCTVSVHVSDRI----------------VPPSFIRKLKDVNAILGASVVLECR 7690
Query: 331 IVVPPWPRSVVWYNKEGKVEAGER 354
V P SV W+ ++ +G +
Sbjct: 7691 -VSGSAPISVGWFQDGNEIVSGPK 7713
Score = 81.0 bits (191), Expect = 6e-15
Identities = 77/289 (26%), Positives = 114/289 (39%), Gaps = 25/289 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S DTG+YT A+N AGSD L V ++PP+F + + V G
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV--------QEPPSFEQTPDSVEVLPGM 7776
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F I + KV W++ R L+ E +I + G ++C
Sbjct: 7777 SLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVT 7836
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
N G ASC+ HL V P FV+ L E G+ + LE G P + W KD
Sbjct: 7837 NDAGSASCTTHLFVKEPAT-----FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDE 7891
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
I + ++T E T L E + Y+ + A ++ + +
Sbjct: 7892 YLISQSERCSITM-TEKSTIL-----EILESTIEDYAQYSCLIENEAGQDIC----EALV 7941
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEA 351
S PP F LE I EP TL C++ P R + WY + K+ +
Sbjct: 7942 SVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIR-ISWYKEHTKLRS 7989
Score = 81.0 bits (191), Expect = 6e-15
Identities = 59/222 (26%), Positives = 93/222 (41%), Gaps = 21/222 (9%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISS 134
G Y ASN G+ ++ +L +S E P P F + + + +G F + +
Sbjct: 8111 GQYNCSASNPLGTASSSAKLILSEHEVP-----PFFDLKPVSVDLALGESGTFKCHVTGT 8165
Query: 135 TECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAH 194
K+TW ++ R + + + G++TC A N+ G+ SCSAH
Sbjct: 8166 APIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAH 8225
Query: 195 LNVLVPKAYKRPEFVEELR--ALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF- 251
L V P P F+++L ++ + ECK+ G P + W+KD EI+ F
Sbjct: 8226 LGVQEP-----PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFR 8280
Query: 252 --------ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L + G YTCEA N G A SS+ + V
Sbjct: 8281 MSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 8322
Score = 80.6 bits (190), Expect = 8e-15
Identities = 68/240 (28%), Positives = 104/240 (43%), Gaps = 31/240 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
R+ +S R D G YT AG + + V L V+A E PP L+ LQ +TV+ G
Sbjct: 3204 RMFISETRQSDAGEYTF----VAGRNRSSVTLYVNAPE------PPQVLQELQPVTVQSG 3253
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF I + K++WY+ E+ L + + DG + +TC A
Sbjct: 3254 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3313
Query: 183 ENVGGRASCSAHLNVLVPKAYK--------RPEFVEELRALLTEQG-TVSLECKVVGVPT 233
+N G A+ SA L+V VP+ P + L+ +T +G +C+V G
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3373
Query: 234 PVLRWFKDSREIKAGDVFALTANAED----------PTSLGTYTCEAVNCMGRAYSSSKV 283
V W+ ++IK F +T ED P GTYT A N +G+ S++ +
Sbjct: 3374 KV-SWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3431
Score = 79.4 bits (187), Expect = 2e-14
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+PTPV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 79.4 bits (187), Expect = 2e-14
Identities = 64/226 (28%), Positives = 101/226 (44%), Gaps = 17/226 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G Y +A N+ G +A L V ++ P P+F R+L+D+ VG F I
Sbjct: 8954 DSGEYICKAENSVGEVSASTFLTVQEQKLP-----PSFSRQLRDVQETVGLPVVFDCAIS 9008
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V+WY++ + L ++ V + G+++CTA N G AS S
Sbjct: 9009 GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSS 9068
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVF 251
A L ++ + P F L + G + EC V G + W KDSREI++G +
Sbjct: 9069 ARL--ILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKY 9126
Query: 252 A---------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
LT D G YTC AVN +G+ ++++++ R
Sbjct: 9127 QISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 9172
Score = 79.0 bits (186), Expect = 2e-14
Identities = 63/245 (25%), Positives = 111/245 (45%), Gaps = 24/245 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S D GVY+ +ASN G+D + L + D P F++ L+ + +
Sbjct: 4535 LELSNLTIQDRGVYSCKASNKFGADICQAELIII--------DKPHFIKELEPVQSAINK 4586
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ ++ + VTW ++ ++L + I + G + CTA
Sbjct: 4587 KVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTAS 4646
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEEL--RALLTEQGTVSLECKVVGVPTPVLRWFKD 241
N G +SCSA + V P P FV+++ L+ + L CK+ G P + WFK+
Sbjct: 4647 NEAGSSSCSATVTVREP-----PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKN 4701
Query: 242 SREI-KAGDVFALTANAE---DPTSL-----GTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
++E+ ++ V N+E D T + G+Y+CEAVN +G S+++ + S
Sbjct: 4702 NKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI 4761
Query: 293 GSLKP 297
+L+P
Sbjct: 4762 KTLEP 4766
Score = 78.6 bits (185), Expect = 3e-14
Identities = 71/293 (24%), Positives = 117/293 (39%), Gaps = 24/293 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y+ + N+ G V + VS P P+F+R+L+D+ +G
Sbjct: 7629 LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVP-----PSFIRKLKDVNAILGA 7683
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S V W+++ ++ + + G +TC A
Sbjct: 7684 SVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAA 7743
Query: 184 NVGGRASCSAHLNVLVPKAYKR-PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
NV G CSA L V P ++++ P+ VE L + +++ + G P ++WFK S
Sbjct: 7744 NVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGM-----SLTFTSVIRGTPPFKVKWFKGS 7798
Query: 243 REIKAGDVFALTANAED-PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
RE+ G+ + + ED T L + + + YS + G AS ++
Sbjct: 7799 RELVPGE--SCNISLEDFVTELELFEVQPLE--SGDYSCLVTNDAGSAS-------CTTH 7847
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
L + P F + L D V P L P P SV W E + ER
Sbjct: 7848 LFVKEPATFVKRLADFSVETGSPIVLEATYTGTP-PISVSWIKDEYLISQSER 7899
Score = 78.6 bits (185), Expect = 3e-14
Identities = 68/234 (29%), Positives = 94/234 (40%), Gaps = 20/234 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV GD+G YT A N G D+ +L + PP+F +RL + TV+
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLI-----PPSFTKRLSE-TVEETE 9190
Query: 124 RTRFLVE--IISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
F +E + S V WY+N + I + G +TC
Sbjct: 9191 GNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCK 9250
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFK 240
N G A C++ + + PK K P F + L + +G V L C V G ++W K
Sbjct: 9251 VSNDAGSALCTSSIVIKEPK--KPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLK 9308
Query: 241 DSREIKAGD----VFAL-TANAE----DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
REIK D FA TA E G Y C+A N G + SKV +
Sbjct: 9309 AGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 9362
Score = 78.2 bits (184), Expect = 4e-14
Identities = 74/295 (25%), Positives = 122/295 (41%), Gaps = 41/295 (13%)
Query: 71 TGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVE 130
T D G Y +A N GSDT +++ ++PP F+ +L LTV G
Sbjct: 6508 TSDIGEYHCKAQNEVGSDTCVCTVKL--------KEPPRFVSKLNSLTVVAGEPAELQAS 6559
Query: 131 IISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRA 189
I + V W + + ++ E+E + I + G++ C +N GG
Sbjct: 6560 IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGME 6619
Query: 190 SCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG 248
A L VL P VE+ + G T +LECKV G P + W+KD + + +
Sbjct: 6620 ENMATLMVLEPAV-----IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSS 6674
Query: 249 D---------VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNS 299
+ +L + + GTYT + N +G++ ++ V V RA
Sbjct: 6675 QKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA---------- 6724
Query: 300 SGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
PP FTR L++ + L C+ V P SV W++++ K+ +G +
Sbjct: 6725 ------VPPSFTRRLKNTGGVLGASCILECK-VAGSSPISVAWFHEKTKIVSGAK 6772
Score = 77.8 bits (183), Expect = 5e-14
Identities = 55/220 (25%), Positives = 95/220 (43%), Gaps = 23/220 (10%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+S AR ++G Y +A N AG+ + + L+V ++PPTF+R L+ + V +
Sbjct: 5848 ISGARVENSGTYVCEARNDAGTASCSIELKV--------KEPPTFIRELKPVEVVKYSDV 5899
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
E+ + +VTW +N R + +++ ++ S F G + C N
Sbjct: 5900 ELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNE 5959
Query: 186 GGRASCSAHLNVLVPKAYKRPEFVEELRALLTE-QGTVSLECKVVGVPTPVLRWFKDSRE 244
GG SCS + + P P F++++ T + + + + V G P + W KD +
Sbjct: 5960 GGSCSCSTRVALKEP-----PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQI 6014
Query: 245 IKAGD---------VFALTANAEDPTSLGTYTCEAVNCMG 275
+ D V L + D G YTC+A N G
Sbjct: 6015 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 6054
Score = 77.0 bits (181), Expect = 9e-14
Identities = 68/235 (28%), Positives = 101/235 (42%), Gaps = 24/235 (10%)
Query: 62 VRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKV 121
V L V+ DT YT + SN AG D L V +E PS P + + D TV+
Sbjct: 6219 VSLEVNNLELEDTANYTCKVSNVAGDDACSGILTV--KEPPSFLVKPGRQQAIPDSTVE- 6275
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
F + + K+ W++++ L+ + I +GS G++TC
Sbjct: 6276 -----FKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCH 6330
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVS-LECKVVGVPTPVLRWF 239
N G SC+ L V P P+FV++L A + + G S LECK+ G P + WF
Sbjct: 6331 VTNDVGSDSCTTMLLVTEP-----PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWF 6385
Query: 240 KDSREIKAGDVFALT---------ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
++ E+ A D + +T N G + CEA N G S+KV V
Sbjct: 6386 RNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 6440
Score = 76.2 bits (179), Expect = 2e-13
Identities = 69/265 (26%), Positives = 103/265 (38%), Gaps = 22/265 (8%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
DD T E L +S G Y QA N AG L V ++P T
Sbjct: 5456 DDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV--------KEPAT 5507
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXX 169
+ V G V+ + E W+++ + L + I +
Sbjct: 5508 ITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIIS 5567
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKV 228
G +T +N GR+SC A +NVL P F ++L+ + + +G+ + LEC V
Sbjct: 5568 TEKKDSGEYTFEVQNDVGRSSCKARINVL--DLIIPPSFTKKLKKMDSIKGSFIDLECIV 5625
Query: 229 VGVPTPVLRWFKDSREIKAGDVFAL-----TANAE----DPTSLGTYTCEAVNCMGRAYS 279
G ++WFKD +EI A + + TA E + T GTYTC A N G
Sbjct: 5626 AGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQC 5685
Query: 280 SSKVHVVGRASREGSLKPNSSGLSP 304
S H+ + KP S ++P
Sbjct: 5686 SG--HLTVKEPPYFVEKPQSQDVNP 5708
Score = 74.1 bits (174), Expect = 7e-13
Identities = 58/232 (25%), Positives = 93/232 (40%), Gaps = 20/232 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G YT Q N G + ++VS P P+F RRL++ +G
Sbjct: 6688 LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVP-----PSFTRRLKNTGGVLGA 6742
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
++ S+ V W+ + +++ + + G +TC A
Sbjct: 6743 SCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAA 6802
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
NV G C A L V P P FV+E L G V+ + G P + WF+ +
Sbjct: 6803 NVAGSDECRAVLTVQEP-----PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 6857
Query: 243 REIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
RE+ GD ++ AE D + G YTC N G+A ++++ V
Sbjct: 6858 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 6909
Score = 73.7 bits (173), Expect = 9e-13
Identities = 65/293 (22%), Positives = 116/293 (39%), Gaps = 20/293 (6%)
Query: 62 VRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKV 121
V L + D G Y + +N GS R+ + +PP+F+++++ +
Sbjct: 5375 VSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL--------REPPSFIKKIESTSSLR 5426
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
G F + S VTW ++ + E + + + + + G++ C
Sbjct: 5427 GGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQ 5486
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A+N G CSA L+V P E + +T+ +L+ K G +WFKD
Sbjct: 5487 AKNDAGIQRCSALLSVKEPATITE----EAVSIDVTQGDPATLQVKFSGTKEITAKWFKD 5542
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
+E+ G + ++ D S+ G Y+ + VGR+ S K +
Sbjct: 5543 GQELTLGSKYKISVT--DTVSILKIISTEKKDSGE-YTFEVQNDVGRS----SCKARINV 5595
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
L PP FT++L+ L C IV P S+ W+ + ++ A E+
Sbjct: 5596 LDLIIPPSFTKKLKKMDSIKGSFIDLEC-IVAGSHPISIQWFKDDQEISASEK 5647
Score = 72.9 bits (171), Expect = 2e-12
Identities = 69/249 (27%), Positives = 96/249 (38%), Gaps = 30/249 (12%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
DR+ G L + D G +T +A+N+ GS + L V ++PP+F
Sbjct: 5084 DRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV--------QEPPSF 5135
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ + V G+ ST + W++ + L+ I ++
Sbjct: 5136 VTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLV 5195
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKV 228
G +TC NV G CSA+L V P FVE+L LL + L CKV
Sbjct: 5196 KTSDSGTYTCKVSNVAGGVECSANLFVKEPAT-----FVEKLEPSQLLKKGDATQLACKV 5250
Query: 229 VGVPTPVLRWFKDSREIKAGD-----------VFALT-ANAEDPTSLGTYTCEAVNCMGR 276
G P + WF + REIK V LT ED G Y CEA N G
Sbjct: 5251 TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDS---GEYMCEAQNEAGS 5307
Query: 277 AYSSSKVHV 285
+ SS V V
Sbjct: 5308 DHCSSIVIV 5316
Score = 72.5 bits (170), Expect = 2e-12
Identities = 58/239 (24%), Positives = 105/239 (43%), Gaps = 24/239 (10%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T+EA L + +T D+G YT + SN AG L V ++P TF+ +L+
Sbjct: 5182 TKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV--------KEPATFVEKLE 5233
Query: 116 -DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+K G T+ ++ + K+TW+ N+R + E+ + + S
Sbjct: 5234 PSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIED 5293
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPT 233
G + C A+N G CS+ +++ K + P F +E + + + ++ V L +V G P
Sbjct: 5294 SGEYMCEAQNEAGSDHCSS---IVIVK--ESPYFTKEFKPIEVLKEYDVMLLAEVAGTPP 5348
Query: 234 PVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ WFKD+ +++G + +L G Y C N +G + S++V
Sbjct: 5349 FEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARV 5407
Score = 72.1 bits (169), Expect = 3e-12
Identities = 63/266 (23%), Positives = 109/266 (40%), Gaps = 22/266 (8%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGD-TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
D++F ++ L + T D G Y +A N +G +L V +P
Sbjct: 4330 DEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP------ 4383
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
R+++ L V +G +F EI S+ + W++ R + E+++ SI
Sbjct: 4384 VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEIL 4443
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECK 227
G +TC A N G SC+A L V +AY P F+ ++L T G + C
Sbjct: 4444 RTQVVDCGEYTCKASNEYGSVSCTATLTVT--EAYP-PTFLSRPKSLTTFVGKAAKFICT 4500
Query: 228 VVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAVNCMGRA 277
V G P W KD + + ++ +AE+ L G Y+C+A N G
Sbjct: 4501 VTGTPVIETIWQKDGAALSPSPNWKIS-DAENKHILELSNLTIQDRGVYSCKASNKFGAD 4559
Query: 278 YSSSKVHVVGRASREGSLKPNSSGLS 303
+++ ++ + L+P S ++
Sbjct: 4560 ICQAELIIIDKPHFIKELEPVQSAIN 4585
Score = 72.1 bits (169), Expect = 3e-12
Identities = 55/224 (24%), Positives = 97/224 (43%), Gaps = 24/224 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKV-G 122
L + A+ D+G Y ASN AGS + + V +PP+F++++ + + G
Sbjct: 4628 LEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV--------REPPSFVKKVDPSYLMLPG 4679
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R ++ S +VTW++N + L E+ V + S G ++C A
Sbjct: 4680 ESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEA 4739
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKD 241
N G SCS + + P P F++ L +GT +L +C+V G + WFKD
Sbjct: 4740 VNDVGSDSCSTEIVIKEP-----PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKD 4794
Query: 242 SREIKAGDVFALTANAE---------DPTSLGTYTCEAVNCMGR 276
++I++ + L + + +G Y C N +G+
Sbjct: 4795 KKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 4838
Score = 72.1 bits (169), Expect = 3e-12
Identities = 56/240 (23%), Positives = 98/240 (40%), Gaps = 21/240 (8%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
++T E + L + ++ D G Y NA+G D+ ++ + +PP F+++
Sbjct: 8843 ITTTEKSAI-LEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL--------EPPYFVKQ 8893
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+ + V VG ++ + E V+WY+ + +L + +
Sbjct: 8894 LEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDIN 8953
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVP 232
G + C AEN G S S L V K P F +LR + G V +C + G
Sbjct: 8954 DSGEYICKAENSVGEVSASTFLTVQEQKL--PPSFSRQLRDVQETVGLPVVFDCAISGSE 9011
Query: 233 TPVLRWFKDSREIK---------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ W+KD + +K + L D + G Y+C A N +G A SS+++
Sbjct: 9012 PISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071
Score = 71.7 bits (168), Expect = 4e-12
Identities = 61/221 (27%), Positives = 91/221 (41%), Gaps = 20/221 (9%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISS 134
G YT A N AGS T+ L V ++P + R + + V G + +
Sbjct: 4919 GKYTCLAENEAGSQTSVGELIV--------KEPAKIIERAELIQVTAGDPATLEYTVAGT 4970
Query: 135 TECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAH 194
E K WY++ R L+ +++ I + G++T N G +SC
Sbjct: 4971 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 5030
Query: 195 LNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
VL P F + LR + GT L+CK+ G + WFKD +EI A D + +
Sbjct: 5031 FTVLDRDI--APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRI 5088
Query: 254 -----TANAE----DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
TA+ E D G +TC A N +G SS + V
Sbjct: 5089 AFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 5129
Score = 71.7 bits (168), Expect = 4e-12
Identities = 69/292 (23%), Positives = 112/292 (38%), Gaps = 24/292 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S D+G YT A+N AG + L V ++PP F+ + Q V T
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV--------KEPPYFVEKPQSQDVNPNT 5710
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R + + + + W+++ + L S+ +D + G + C
Sbjct: 5711 RVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS 5770
Query: 184 NVGGRASCSAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A+ A L V P + K+P V LR Q T + EC++ G P + W+ D
Sbjct: 5771 NDVGTATSKATLFVKEPPQFIKKPSPVLVLR---NGQST-TFECQITGTPKIRVSWYLDG 5826
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
EI A ++ L T+ G +S +V A + S L
Sbjct: 5827 NEITAIQKHGISFI----DGLATFQIS-----GARVENSGTYVC-EARNDAGTASCSIEL 5876
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ PP F REL+ V L C++ P P V W ++ + ++
Sbjct: 5877 KVKEPPTFIRELKPVEVVKYSDVELECEVTGTP-PFEVTWLKNNREIRSSKK 5927
Score = 70.5 bits (165), Expect = 8e-12
Identities = 72/294 (24%), Positives = 118/294 (40%), Gaps = 41/294 (13%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISS 134
G Y+ A+N GS ++ RL ++ G++PP F RL + VG F + +
Sbjct: 9052 GQYSCTATNPIGSASSSARLILT-----EGKNPPFFDIRLAPVDAVVGESADFECHVTGT 9106
Query: 135 TECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAH 194
KV+W ++ R + + I + G++TC A N G+ SC+A
Sbjct: 9107 QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQ 9166
Query: 195 LNV---LVPKAYKR--PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKA-- 247
LN+ L+P ++ + E VEE TE + LE +V G + W+K++ EI+
Sbjct: 9167 LNIKERLIPPSFTKRLSETVEE-----TEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTS 9221
Query: 248 -------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
+ L G YTC+ N G A +S + +
Sbjct: 9222 NCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK-------------- 9267
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
P+ PP+F + L V E LSC V P + W +++ +R
Sbjct: 9268 --EPKKPPVFDQHLTPVTVSEGEYVQLSCH-VQGSEPIRIQWLKAGREIKPSDR 9318
Score = 68.1 bits (159), Expect = 4e-11
Identities = 53/214 (24%), Positives = 90/214 (42%), Gaps = 24/214 (11%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT +A NAAGS ++ L+V ++PP F ++ + G E+
Sbjct: 8299 DSGDYTCEAHNAAGSASSSTSLKV--------KEPPIFRKKPHPIETLKGADVHLECELQ 8350
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
+ V+WY+++R L ++ I+ + G + C A N G +C
Sbjct: 8351 GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCV 8410
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREI------ 245
+ + P P FV++L + T G V L+ + G + WFKD EI
Sbjct: 8411 GSIALKAP-----PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDN 8465
Query: 246 ----KAGDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ ++ L + +P + G YTC+ N G
Sbjct: 8466 IWISYSENIATLQFSRVEPANAGKYTCQIKNDAG 8499
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/232 (25%), Positives = 94/232 (40%), Gaps = 21/232 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G YT +ASN GS + L V+ PPTFL R + LT VG
Sbjct: 4440 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY------PPTFLSRPKSLTTFVGK 4493
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+F+ + + + W ++ L + I + G ++C A
Sbjct: 4494 AAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKAS 4553
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTE-QGTVSLECKVVGVPTPVLRWFKDS 242
N G C A L ++ +P F++EL + + V LEC+V + W KD
Sbjct: 4554 NKFGADICQAELIII-----DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDG 4608
Query: 243 REIKAGDVFAL-----TANAEDPTS----LGTYTCEAVNCMGRAYSSSKVHV 285
+++ G + + A E P + GTY C A N G + S+ V V
Sbjct: 4609 QKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/251 (23%), Positives = 104/251 (41%), Gaps = 14/251 (5%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFC 164
++PPTF++++ DL G + S VTW + + + E ++ +
Sbjct: 4848 KEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 4907
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQGTVS 223
G++TC AEN G + L V P K +R E ++ +T +
Sbjct: 4908 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ-----VTAGDPAT 4962
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
LE V G P +W+KD R + A + ++ + L Y+ E ++ G+ Y+
Sbjct: 4963 LEYTVAGTPELKPKWYKDGRPLVASKKYRISFK-NNVAQLKFYSAE-LHDSGQ-YTFEIS 5019
Query: 284 HVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWY 343
+ VG +S E + + L + P FT+ L + + L C+I P V W+
Sbjct: 5020 NEVGSSSCETTF----TVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKI-AGSLPMRVSWF 5074
Query: 344 NKEGKVEAGER 354
++ A +R
Sbjct: 5075 KDGKEIAASDR 5085
Score = 63.7 bits (148), Expect = 9e-10
Identities = 39/184 (21%), Positives = 82/184 (44%), Gaps = 14/184 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ + D+G Y+ +A N GSD+ + + ++PP+F++ L+ + GT
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI--------KEPPSFIKTLEPADIVRGT 4773
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E+ + +++W+++++++ +++ + S C G + C
Sbjct: 4774 NALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVA 4833
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G+ C A + P P FV+++ L+ G TV+L+ V G + W K
Sbjct: 4834 NEVGKCGCMATHLLKEP-----PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQ 4888
Query: 243 REIK 246
I+
Sbjct: 4889 EVIR 4892
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/239 (24%), Positives = 98/239 (41%), Gaps = 24/239 (10%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
TE++ + + ST D Y+ N AG D + V +PP F+ L+
Sbjct: 7905 TEKSTILEILESTIE--DYAQYSCLIENEAGQDICEALVSVL--------EPPYFIEPLE 7954
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+ +G ++ + E +++WY+ +L A + +
Sbjct: 7955 HVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDV 8014
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEF-VEELRALLTEQG-TVSLECKVVGVPT 233
G ++C A+N G + SA VLV K K P F +L+ + G V+ EC++ G
Sbjct: 8015 GEYSCKADNSVGAVASSA---VLVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEP 8071
Query: 234 PVLRWFKDSREIK---------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ W+KD +K +V L D + +G Y C A N +G A SS+K+
Sbjct: 8072 LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130
Score = 62.5 bits (145), Expect = 2e-09
Identities = 56/232 (24%), Positives = 86/232 (37%), Gaps = 20/232 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L S + G YT Q N AG L V +P T + + + + V G
Sbjct: 8477 LQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL--------EPATIVEKPESIKVTTGD 8528
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + E W+++ + L + I G ++ +
Sbjct: 8529 TCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQ 8588
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
N G+ SC+A L V P F +L+ G+ V +ECKV G P + WF +
Sbjct: 8589 NPVGKDSCTASLQV--SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEG 8646
Query: 243 REIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
EI +G + ALT N + + G YTC A N G S+ + V
Sbjct: 8647 NEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 8698
Score = 62.1 bits (144), Expect = 3e-09
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P F++ + + + +G V +I + K+ W+ N L + V DG
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNV--------------LVPKAYKR------PE 207
G +TC A N G+ CSA+L + V K+ ++ P
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622
Query: 208 FVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKDSREIKAGDVFALTAN--------AE 258
F++EL+ + QG ++ E VVG P P + WFK+++++ + + N
Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3682
Query: 259 DP--TSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
DP G Y C+A N +G + ++++ V+ + + P + +PE P F
Sbjct: 3683 DPQREDSGLYICKAENMLGESTCAAELLVL-LEDTDMTDTPCKAKSTPEAPEDF 3735
Score = 60.1 bits (139), Expect = 1e-08
Identities = 61/246 (24%), Positives = 98/246 (39%), Gaps = 20/246 (8%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
+L +A D+G YT + SN GS + V + P F + L+++ V
Sbjct: 5000 QLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIA-----PFFTKPLRNVDSVVN 5054
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R +I S +V+W+++ + + ++R I G +TC A
Sbjct: 5055 GTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRA 5114
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKD 241
N G S L V P P FV + + G+ V L+ G +RWFK
Sbjct: 5115 TNSVGSKDSSGALIVQEP-----PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKG 5169
Query: 242 SREIKAGDVFALTANA-EDPTSL--------GTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
++E+ +G +T A E L GTYTC+ N G S+ + V A+
Sbjct: 5170 NKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFV 5229
Query: 293 GSLKPN 298
L+P+
Sbjct: 5230 EKLEPS 5235
Score = 60.1 bits (139), Expect = 1e-08
Identities = 51/222 (22%), Positives = 90/222 (40%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + G +G YT QA N +G + L V ++P + + + + V
Sbjct: 6032 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLV--------QEPAQIVEKAKSVDVTEKD 6083
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + E KV W ++ ++++ + S+ + + G++T E
Sbjct: 6084 PMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVE 6143
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
N G +SC A+L VL P F ++L + G+ + +ECKV G +WFKD
Sbjct: 6144 NDFGSSSCDAYLRVLDQNI--PPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDG 6201
Query: 243 REIKAGDVF---------ALTANAEDPTSLGTYTCEAVNCMG 275
+EI + +L N + YTC+ N G
Sbjct: 6202 KEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAG 6243
Score = 58.0 bits (134), Expect = 5e-08
Identities = 60/250 (24%), Positives = 95/250 (38%), Gaps = 26/250 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L V A D G+YT + SN AGS + + + P P F + L +TV G
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKP-----PVFDQHLTPVTVSEGE 9288
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + S ++ W + R + ++R S G + C A
Sbjct: 9289 YVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKAS 9348
Query: 184 NVGGRASCSAHLNV-----LVPKAYK-----RPEFVEELRAL-LTEQGTVSLECKVVGVP 232
NV G + + + + + P K R FV E +++ + E+ T + KV G P
Sbjct: 9349 NVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 9408
Query: 233 TPVLRWFKDS-REI---------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK 282
P ++W K R++ + GD L T G Y C A N G S+
Sbjct: 9409 IPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVN 9468
Query: 283 VHVVGRASRE 292
+ V R +E
Sbjct: 9469 LQVDERKKQE 9478
Score = 56.4 bits (130), Expect = 1e-07
Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 15/178 (8%)
Query: 76 VYTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEI 131
V+TL + D V+L ++ + E P F + L+D TV+ G T L
Sbjct: 13176 VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGA-TAVLECE 13234
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+S KV W++N +L++++ IV DG +TC A++ + SC
Sbjct: 13235 VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSC 13292
Query: 192 SAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG 248
+LNV+ P EF+ L L + E+ EC++ V +WFKD EIK G
Sbjct: 13293 --NLNVVPPHV----EFLRPLTDLQVREKEMARFECELSRENAKV-KWFKDGAEIKKG 13343
Score = 55.2 bits (127), Expect = 3e-07
Identities = 75/315 (23%), Positives = 123/315 (39%), Gaps = 41/315 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+ DR +E RL + + R D G YT+ AG + + +L V G D
Sbjct: 3099 ITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV----VAGGNVSTAKLFVE------GRD-- 3146
Query: 109 TFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRN--ERRLLEAERVSIVRDGSFFCX 165
+R ++ V+V + R +VE ++ + WY++ E ER V +
Sbjct: 3147 VRIRSIKK-EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM 3205
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G +T A GR S L V P+ P+ ++EL+ + + G +
Sbjct: 3206 FISETRQSDAGEYTFVA----GRNRSSVTLYVNAPEP---PQVLQELQPVTVQSGKPARF 3258
Query: 226 CKVV-GVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMG 275
C V+ G P P + W+K+ + + G + L P YTCEA N G
Sbjct: 3259 CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 3318
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPP 335
A +S+ + V + P+ P PP L+D +P C+ V
Sbjct: 3319 VATTSASLSV----EVPEVVSPDQE--MPVYPPAIITPLQDTVTSEGQPARFQCR--VSG 3370
Query: 336 WPRSVVWYNKEGKVE 350
V WY+K+ K++
Sbjct: 3371 TDLKVSWYSKDKKIK 3385
Score = 54.4 bits (125), Expect = 6e-07
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 93 RLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE-- 150
RLE + E P F+ + G RF ++++ + W+ + ++++
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 151 AERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVE 210
+V I DG+ G WT A+N GR+S S L V + +P FVE
Sbjct: 1502 THKVVIKEDGTQ-SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 211 ELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
+L+ + ++G+ + ++ + G P P + W K+S
Sbjct: 1561 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNS 1593
Score = 52.4 bits (120), Expect = 2e-06
Identities = 63/286 (22%), Positives = 106/286 (37%), Gaps = 25/286 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT++ A D+G Y +A N G + L V A PP F ++ + G+
Sbjct: 7349 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKA--------PPVFTQKPSPVGALKGS 7400
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
EI + +V W ++ +++ +++ I G + C A
Sbjct: 7401 DVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKAT 7460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
N G +CS + P P FV++L T G V L V G + W KD
Sbjct: 7461 NEVGSDTCSCSVKFKEP-----PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKD- 7514
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
G+V + N T + A +G +S+ + + + ++ S+ L
Sbjct: 7515 ----RGEVIRESEN----TRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVL 7566
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ P + E V PF L C + P S W+ K+G+
Sbjct: 7567 TVLEPARIIEKPEPMTVTTGNPFALECVVTGTP-ELSAKWF-KDGR 7610
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
E SPS E P F R+Q TV G+ F V ++ + + WY+N ++ ++R+
Sbjct: 2070 ELSPSMEAPKIF-ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYW 2128
Query: 159 DGSFFC-XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT 217
C A N+ G S A L V +A + F +EL+ ++
Sbjct: 2129 PEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV---QAKQLITFTQELQDVVA 2185
Query: 218 -EQGTV-SLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
E+ T+ + EC+ P ++W+KD E+ GD + +
Sbjct: 2186 KEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYRM 2222
Score = 50.4 bits (115), Expect = 9e-06
Identities = 62/242 (25%), Positives = 92/242 (38%), Gaps = 32/242 (13%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA 98
N K + A L +E G + L + R TG QA+N S RV+ V
Sbjct: 13065 NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIG 13124
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
LR L+D+TV G F E+ S + V WY ++L +++V
Sbjct: 13125 -----------LLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKVVPRS 13172
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTE 218
+G G TA++ H N+ V + EF + L E
Sbjct: 13173 EGKVHTLTLRDVKLEDAGEVQLTAKDF------KTHANLFVKEP--PVEFTKPLEDQTVE 13224
Query: 219 QG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE---------DPTSLGTYTC 268
+G T LEC+V V +WFK+ EI + + A+ P + TYTC
Sbjct: 13225 EGATAVLECEVSRENAKV-KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 13283
Query: 269 EA 270
+A
Sbjct: 13284 DA 13285
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V +E G L + A D+G +T+ A N AG + V L V A E + P F+ +
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH---QVKPMFVEK 1561
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF-CXXXXXXXX 172
L+++ +K G++ V + + W +N ++ + I +G+
Sbjct: 1562 LKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTV 1621
Query: 173 XXXGRW-TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
W T TA N GR + +NV V A PE R L+ +GT
Sbjct: 1622 SQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE-----RKLIIPRGT 1666
Score = 49.2 bits (112), Expect = 2e-05
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 6/152 (3%)
Query: 51 DRFVST-EEAGGVRLTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPP 108
D++V+ E ++ V+ G Y ++A N G S +R E+ A ++ E P
Sbjct: 14559 DKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQ--EAPE 14616
Query: 109 TFL--RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
FL + L LTVK GT+ + E K+TW + + L + +R++I
Sbjct: 14617 IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVT 14676
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
G + A NV GRA+ +NVL
Sbjct: 14677 IVDSKRSDTGTYIIEAVNVCGRATAVVEVNVL 14708
Score = 48.0 bits (109), Expect = 5e-05
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 7/152 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V ++ GV +T +T R + L A ++TARV V E P PPT +
Sbjct: 896 VEVKKEVGVSITGTTVR--EERFEVLHGREAKVTETARVPAPV---EIPV--TPPTLVSG 948
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+++TV G I VTWYR + ++ + I
Sbjct: 949 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 1008
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKR 205
GR+TC+A N G S S +L V V + +++
Sbjct: 1009 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 1040
Score = 48.0 bits (109), Expect = 5e-05
Identities = 48/205 (23%), Positives = 75/205 (36%), Gaps = 15/205 (7%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
+S + + A V+++ AE ED P L D + G I ++ E V
Sbjct: 4263 SSESGTEEVATVKIQ-EAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE--VN 4319
Query: 141 WYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
WY + + E+ ++D ++ G + C A N G+ + SA L V+
Sbjct: 4320 WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 4379
Query: 200 PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD---------V 250
A +E L L C++ P +WFK REI D +
Sbjct: 4380 RAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4437
Query: 251 FALTANAEDPTSLGTYTCEAVNCMG 275
+L G YTC+A N G
Sbjct: 4438 SSLEILRTQVVDCGEYTCKASNEYG 4462
Score = 47.6 bits (108), Expect = 7e-05
Identities = 46/170 (27%), Positives = 72/170 (42%), Gaps = 20/170 (11%)
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXX 169
FL L+D+T K F VE+ S +V W++N++RL VS+ +G
Sbjct: 12858 FLTPLKDVTAKEKESAVFTVEL-SHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKD 12916
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL-TEQGTVSLECKV 228
+ E +G S A L VL Y F +L+ E+ V L+C++
Sbjct: 12917 LSIDDTSQ--IRVEAMG--MSSEAKLTVLEGDPY----FTGKLQDYTGVEKDEVILQCEI 12968
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAED---------PTSLGTYTCE 269
PV +WFKD +EIK + A+ + + +G YTC+
Sbjct: 12969 SKADAPV-KWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 13017
Score = 44.0 bits (99), Expect = 8e-04
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 10/174 (5%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVS-------AEESPS 103
DR + +G L + D+G Y +ASN AGSDT + ++ + A + +
Sbjct: 9317 DRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAA 9376
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNE-RRLLEAERVSIVRDGSF 162
+ F+ Q + V T F+ ++ V W + + R+L + RV I + G
Sbjct: 9377 VDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDE 9436
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
G + C A N G +++N+ V + K+ + +LRA+L
Sbjct: 9437 AKLEIRDTTKTDSGLYRCVAFNEHG--EIESNVNLQVDERKKQEKIEGDLRAML 9488
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 1/113 (0%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
DT + E G PP FL+ L+ + G F ++ VTW++ ++
Sbjct: 3601 DTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ 3660
Query: 148 LLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
L + +I+ + G + C AEN+ G ++C+A L VL+
Sbjct: 3661 LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3713
Score = 42.3 bits (95), Expect = 0.002
Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 21/193 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ ++ D GVYT + G T+ RL V+ F+ L+D TVK G
Sbjct: 12468 LVINDSQFDDEGVYTAEVE---GKKTS-ARLFVTGIRLK-------FMSPLEDQTVKEGE 12516
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F+ E+ S + V W++N+ +L + V I +G + +
Sbjct: 12517 TATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK 12575
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
+ S +A L VL Y + ++ E+ ++L+C+V PV +WFKD
Sbjct: 12576 EL----SSTAQLKVLEADPYFTVKLHDKTAV---EKDEITLKCEV-SKDVPV-KWFKDGE 12626
Query: 244 EIKAGDVFALTAN 256
EI +++ A+
Sbjct: 12627 EIVPSPKYSIKAD 12639
Score = 41.5 bits (93), Expect = 0.004
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAV 271
V+ CK+ G P P + W+KD + IK G+ + + + SL G YT A
Sbjct: 1308 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1367
Query: 272 NCMGRAYSSSKVHV 285
N G A S K++V
Sbjct: 1368 NIKGNAICSGKLYV 1381
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 15/127 (11%)
Query: 196 NVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-- 252
NV+ +P E ++ +G +S+ VP P + W KD +E+KA D
Sbjct: 15304 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 15363
Query: 253 ---LTANAEDPTSL----GTYTCEAVNCMGRAYSSSKVHVVG-----RASREGSLKPNSS 300
++A+ E P S+ G YT N +G A +S V V+G + + + +S
Sbjct: 15364 NDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSC 15423
Query: 301 GLSPEPP 307
L+ EPP
Sbjct: 15424 KLTWEPP 15430
Score = 41.5 bits (93), Expect = 0.004
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+TV+VG R L + E +TW + + L+ +RV +++D G
Sbjct: 18845 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 18904
Query: 177 RWTCTAENVGGRASCSAHLNVL 198
++ +A+N G A SA +NVL
Sbjct: 18905 KYIISAKNSSGHAQGSAIVNVL 18926
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWF---------KDSREIKAGDVFALTA 255
P F++E+ G V+ L V+G+P P ++WF D + + GD +L
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASR----EGSLKPNSSGLSPEPPPI 309
G YTC A N G+ S+ K++ G + E ++ + L PP
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
F +EL+ P +V P P +V W+ KE K
Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAP-TVTWF-KENK 3659
Score = 39.1 bits (87), Expect = 0.023
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 12/98 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
+LT++ R D G YT + + LE SAE E P F +R+Q++ V
Sbjct: 9727 KLTIADVRAEDQGQYTCKYED----------LETSAELRIEAE-PIQFTKRIQNIVVSEH 9775
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
F E+ S + VTWY+ L E+++ + DG
Sbjct: 9776 QSATFECEV-SFDDAIVTWYKGPTELTESQKYNFRNDG 9812
Score = 38.7 bits (86), Expect = 0.031
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALT---------- 254
P V L+ + +G +V+LEC + G P+P + W+++ +I++ F +T
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 255 --ANAEDPTSLGTYTCEAVNCMGRAYSS 280
A AED G +TC AVN G +S
Sbjct: 1003 REAFAEDS---GRFTCSAVNEAGTVSTS 1027
Score = 38.7 bits (86), Expect = 0.031
Identities = 31/138 (22%), Positives = 55/138 (39%), Gaps = 5/138 (3%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLE-VSAEESPSGEDPPTFLRRLQD-LTVK 120
+ TV + GDT Y + A N G + ++ ++ + PPT +D LT++
Sbjct: 17702 KYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA---PPTLHLDFRDKLTIR 17758
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
VG + KV+W+++E +LE +R I + G++
Sbjct: 17759 VGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCV 17818
Query: 181 TAENVGGRASCSAHLNVL 198
EN G +NV+
Sbjct: 17819 VVENSTGSRKGFCQVNVV 17836
Score = 38.3 bits (85), Expect = 0.040
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 17/124 (13%)
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFK 240
A N G + SA + + P ++ + E+GT V++ K+ GVP P L WFK
Sbjct: 17020 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 17079
Query: 241 ------DSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVH 284
D++E + D L + G YT AVN +G A +++
Sbjct: 17080 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 17139
Query: 285 VVGR 288
V+GR
Sbjct: 17140 VLGR 17143
Score = 37.9 bits (84), Expect = 0.053
Identities = 49/193 (25%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL ++ + D G YT + + + S +L+V A + + L++LTV
Sbjct: 2675 RLIIAATKLDDIGEYTYKVATSKTS----AKLKVEAVK---------IKKTLKNLTVTET 2721
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
F VE+ V W +N L E+ +I G+ + +
Sbjct: 2722 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL 2781
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
GR SA L+V K K+P+ V L E TV+ E V PV +WF +
Sbjct: 2782 ----GRLGASARLHVETVKIIKKPKDVTAL-----ENATVAFEVSVSHDTVPV-KWFHKN 2831
Query: 243 REIKAGDVFALTA 255
EIK D L +
Sbjct: 2832 VEIKPSDKHRLVS 2844
Score = 37.5 bits (83), Expect = 0.071
Identities = 36/145 (24%), Positives = 66/145 (45%), Gaps = 11/145 (7%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRNERRLLEAERVSIVRDGS 161
S +P T ++ +++ TV F ++I I+ E K++WY+ +L +++ I DG
Sbjct: 9578 SQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 9637
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
G + V G SA L V+ P A++R ++++ L E T
Sbjct: 9638 RHTLRVKNCQLKDQGNYRL----VCGPHIASAKLTVIEP-AWER--HLQDV--TLKEGQT 9688
Query: 222 VSLECKVVGVPTPVLRWFKDSREIK 246
++ C+ VP WF++ R +K
Sbjct: 9689 CTMTCQ-FSVPNVKSEWFRNGRILK 9712
Score = 37.5 bits (83), Expect = 0.071
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 16/143 (11%)
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGT-VSLECKVVGVPTPVLRW 238
TA N+ + S + +L R + +++LLT + GT V L+ V G P P + W
Sbjct: 20197 TAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSW 20256
Query: 239 FKDSREIK--AGDVFALTAN-------AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA 289
KD +K G A+ N + + G YT A N G ++ K+ V+ +
Sbjct: 20257 KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 20316
Query: 290 SREGSLKPNS-----SGLSPEPP 307
S+K N + LS EPP
Sbjct: 20317 GPPASVKINKMYSDRAMLSWEPP 20339
Score = 37.5 bits (83), Expect = 0.071
Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 6/146 (4%)
Query: 58 EAGGVR-LTVSTARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRL 114
EAG + LT + R + Y ++A N AG R + P E P L +
Sbjct: 29521 EAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIE-PTADLTGI 29579
Query: 115 --QDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
Q +T K G+ V I KVTW E RL E +RVSI
Sbjct: 29580 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMR 29639
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVL 198
GR+ T EN G + S + V+
Sbjct: 29640 GDSGRYFLTLENTAGVKTFSVTVVVI 29665
Score = 36.7 bits (81), Expect = 0.12
Identities = 40/158 (25%), Positives = 59/158 (37%), Gaps = 3/158 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
E + V+ R G T + + A NAAG SD A V V ++ + +
Sbjct: 18094 ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAR 18153
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+ +KVG R I KVTW + +R R+ + GS
Sbjct: 18154 EQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKL--EIRNAAHEDG 18211
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR 213
G ++ T EN G + S + VL R V E+R
Sbjct: 18212 GIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIR 18249
Score = 35.9 bits (79), Expect = 0.22
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
E P F+ L+D TV F ++ S + V WYRN R + E ++ +DGS
Sbjct: 13747 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYKFEKDGS 13802
Score = 35.9 bits (79), Expect = 0.22
Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 9/82 (10%)
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAV 271
+V L + G P P + W+KD +E++ D+ ++ D + G Y +
Sbjct: 27816 SVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLR 27875
Query: 272 NCMGRAYSSSKVHVVGRASREG 293
N MG A ++ +V ++ + G
Sbjct: 27876 NAMGSASATIRVQILDKPGPPG 27897
Score = 35.9 bits (79), Expect = 0.22
Identities = 42/202 (20%), Positives = 79/202 (39%), Gaps = 12/202 (5%)
Query: 50 DDRFVSTEEAGGVRLT---VSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGE 105
++ + + G VR T VS + G + + A N AG + + V A++
Sbjct: 28137 EEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP 28196
Query: 106 DPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
+ + + K G + L+ VTW ++E+ L R SI S
Sbjct: 28197 EIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLL 28256
Query: 166 XXXXXXXXXXGRWTCTAEN-VGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G++ T EN VG S + + VL P ++L+ +GTV+L
Sbjct: 28257 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVL-----DTPAACQKLQVKHVSRGTVTL 28311
Query: 225 --ECKVVGVPTPVLRWFKDSRE 244
+ ++ +P++ + + R+
Sbjct: 28312 LWDPPLIDGGSPIINYVIEKRD 28333
Score = 35.5 bits (78), Expect = 0.28
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 21/242 (8%)
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+D VK F E+ ++ K W+RNE + ++ + I++ +
Sbjct: 13573 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 13631
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGTVSLECKVVGVP 232
+ + N G SA N++V + R VE L+ + T E+ +V+ CKV +
Sbjct: 13632 DQANYNVSLTNHRGENVKSA-ANLIVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL- 13687
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
L+W K+ E+ + + + + +C + ++V
Sbjct: 13688 NVTLKWTKNGEEVPFDNRVSYRVDKY------KHMLTIKDC---GFPDEGEYIV----TA 13734
Query: 293 GSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAG 352
G K + L E P F LEDQ V + SCQ+ +V WY +++ G
Sbjct: 13735 GQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQL--SREKANVKWYRNGREIKEG 13792
Query: 353 ER 354
++
Sbjct: 13793 KK 13794
Score = 35.5 bits (78), Expect = 0.28
Identities = 37/199 (18%), Positives = 72/199 (36%), Gaps = 5/199 (2%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
V+ + G T + ++A N G + + +E ++ ++ L VK GT
Sbjct: 18396 VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTV 18455
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
RF I W + + E ++ D G + T N
Sbjct: 18456 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA 18515
Query: 186 GGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSRE 244
G + + HL VL VP P + + + E T+S + +PV+ + + ++
Sbjct: 18516 AGSKTVAVHLTVLDVPGPPTGPINILD---VTPEHMTISWQPPKDDGGSPVINYIVEKQD 18572
Query: 245 IKAGDVFALTANAEDPTSL 263
+ D + + ++ T L
Sbjct: 18573 TRK-DTWGVVSSGSSKTKL 18590
Score = 35.5 bits (78), Expect = 0.28
Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 5/149 (3%)
Query: 96 VSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVS 155
+ AE P D ++ L LTVK GT + V+W ++ L AE +
Sbjct: 20213 ILAENVPPRIDLSVAMKSL--LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK 20270
Query: 156 IVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL 215
+ + G +T TAEN G S + L VL P ++ +
Sbjct: 20271 MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG---PPASVKINKM 20327
Query: 216 LTEQGTVSLECKVVGVPTPVLRWFKDSRE 244
+++ +S E + + + + D RE
Sbjct: 20328 YSDRAMLSWEPPLEDGGSEITNYIVDKRE 20356
Score = 33.9 bits (74), Expect = 0.87
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 206 PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREI------KAGDVFALTA-NAE 258
PE+ + L ++ ++ ++ V G P P + WFKD EI + DV T+
Sbjct: 28889 PEYFDGL--IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVR 28946
Query: 259 DPT--SLGTYTCEAVNCMGRAYSSSKVHV 285
D T G YT EA N G A + KV V
Sbjct: 28947 DATRDHRGVYTVEAKNASGSAKAEIKVKV 28975
Score = 33.9 bits (74), Expect = 0.87
Identities = 16/41 (39%), Positives = 24/41 (58%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
T+ G L V A GVYT++A NA+GS A ++++V
Sbjct: 28935 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 28975
Score = 33.5 bits (73), Expect = 1.1
Identities = 39/182 (21%), Positives = 70/182 (38%), Gaps = 21/182 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G Y + ++ +V E++AE F+ + Q+L + G
Sbjct: 13446 LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAE----------FISKPQNLEILEGE 13494
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ F+ I S V W R+++ L ++ ++ DG G +
Sbjct: 13495 KAEFVCSI-SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV- 13552
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G A +AHL V+ P +++ R + EQ V C+ V +WF++
Sbjct: 13553 ---GAARAAAHLTVIEKLRIVVP--LKDTR--VKEQQEVVFNCE-VNTEGAKAKWFRNEE 13604
Query: 244 EI 245
I
Sbjct: 13605 AI 13606
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/43 (44%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
V T+ V LT+ DTG Y + SNAAGS T V L V
Sbjct: 18486 VETDNFSSV-LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 18527
Score = 33.1 bits (72), Expect = 1.5
Identities = 29/139 (20%), Positives = 53/139 (38%), Gaps = 4/139 (2%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ G+ V G+ + + A N+AG R V +E P
Sbjct: 21936 DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTML--PELD 21993
Query: 111 LRRL-QDLTV-KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
LR + Q L + K G + + ++ + VTW + ++ L + +RV+ +
Sbjct: 21994 LRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNIN 22053
Query: 169 XXXXXXXGRWTCTAENVGG 187
G + TA N+ G
Sbjct: 22054 ECVRSDSGPYPLTARNIVG 22072
Score = 32.7 bits (71), Expect = 2.0
Identities = 32/158 (20%), Positives = 57/158 (36%), Gaps = 3/158 (1%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
DR+ + L V+ + G + + A NA G R V E+ PP
Sbjct: 19772 DRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVY--EAKEQLLPPKI 19829
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
L Q +T+K G + R + W + E ++ + +++ + S
Sbjct: 19830 LMPEQ-ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDV 19888
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEF 208
G ++ TAEN G + + V+ +P F
Sbjct: 19889 TRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 19926
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 10/90 (11%)
Query: 209 VEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANAEDP 260
V+ L L + GT + L V G P P + W K +K + T D
Sbjct: 14621 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS 14680
Query: 261 --TSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
+ GTY EAVN GRA + +V+V+ +
Sbjct: 14681 KRSDTGTYIIEAVNVCGRATAVVEVNVLDK 14710
Score = 31.9 bits (69), Expect = 3.5
Identities = 51/223 (22%), Positives = 88/223 (39%), Gaps = 22/223 (9%)
Query: 107 PPTFLRRLQDLTVK----VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
P F++ ++D+ + VG+ F ++S + TW ++ + E+ + + DG
Sbjct: 12041 PLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIADGKD 12099
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV 222
G +TC +G + S V+ + + +EE ++ Q +
Sbjct: 12100 RKLHIIDVQLSDAGEYTCVLR-LGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ-PL 12157
Query: 223 SLECKVVGVPTPVLRWFKDSREI--KAGDVF--------ALTANAEDPTSLGTYTCEAVN 272
L C++ V W KD + + K G + ALT N D T GTYT N
Sbjct: 12158 YLSCELNKERDVV--WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN 12215
Query: 273 CMGRAYSSSKVHVVGRASREGSLKP-NSSGLSPEPPPIFTREL 314
SS V VV R+ +KP + P+ IF ++
Sbjct: 12216 A-NNLECSSCVKVV-EVIRDWLVKPIRDQHVKPKGTAIFACDI 12256
Score = 31.9 bits (69), Expect = 3.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
L + +R DTG+YT+ A N G+ + +RL V P
Sbjct: 17108 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGP 17146
Score = 31.1 bits (67), Expect = 6.1
Identities = 17/49 (34%), Positives = 24/49 (48%)
Query: 53 FVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
F T+ +L ++ A D G YT ASNA G ++ L + A ES
Sbjct: 3390 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3438
Score = 31.1 bits (67), Expect = 6.1
Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 21/190 (11%)
Query: 63 RLTVSTARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD-LTV 119
+L + + D G YT L+ N + TA++ +E E P F++ L++ +TV
Sbjct: 12101 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE---------ELPVRFVKTLEEEVTV 12151
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRW 178
G E+ + E V W ++ + ++E R+ G G +
Sbjct: 12152 VKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 12209
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLR 237
T T EN CS+ + V+ R V+ +R + +GT C + TP ++
Sbjct: 12210 TVTVENANN-LECSSCVKVV---EVIRDWLVKPIRDQHVKPKGTAIFACDIAK-DTPNIK 12264
Query: 238 WFKDSREIKA 247
WFK EI A
Sbjct: 12265 WFKGYDEIPA 12274
Score = 30.7 bits (66), Expect = 8.1
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
VS EA L++ A D G YT+ ASN GS V +EV SP
Sbjct: 16380 VSRSEAK-TELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSP 16427
>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
preferentially expressed protein protein.
Length = 3094
Score = 90.6 bits (215), Expect = 7e-18
Identities = 88/325 (27%), Positives = 132/325 (40%), Gaps = 30/325 (9%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAE-ESPSGEDPPTF 110
RF E G RL + A GD G YT +A N G+ RLEV A ES S
Sbjct: 786 RFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRS----LAV 841
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA-ERVSIVRDGSFFCXXXXX 169
L LQD+ V G F + T+ +V W R L A + + DG
Sbjct: 842 LAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTS 901
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVV 229
G +TC +CSA L V A +E++ L E +CK+
Sbjct: 902 VHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVL--EGRAARFDCKIS 959
Query: 230 GVPTPVLRW------FKDSREIKA---GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
G P PV+ W ++S ++ G + +L G Y AVN G+A+ S
Sbjct: 960 GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCS 1019
Query: 281 SKVHV-VGRASREG-SLKPNSSGLSPEPP----------PIFTRELEDQYVRICEPFTLS 328
++++V R + G S K PE P P F R L+D V + + L
Sbjct: 1020 AQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLE 1079
Query: 329 CQIVVPPWPRSVVWYNKEGKVEAGE 353
CQ+ P+P ++ W++ ++++ +
Sbjct: 1080 CQVTGLPYP-TISWFHNGHRIQSSD 1103
Score = 65.7 bits (153), Expect = 2e-10
Identities = 71/259 (27%), Positives = 101/259 (38%), Gaps = 42/259 (16%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
+L +++ D+GVYT + S A T RL V +P F R L+D+ V G
Sbjct: 896 KLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAP------LFTRLLEDVEVLEG 949
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF +I + VTW + E+E + + +DG G + +A
Sbjct: 950 RAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSA 1009
Query: 183 ENVGGRASCSAHLNVLVP---------KAYKRPEFVEE--------------LRALLT-E 218
N G+A CSA L V P K K P EE LR L E
Sbjct: 1010 VNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLE 1069
Query: 219 QGTVS---LECKVVGVPTPVLRWFKDSREIKAGD---------VFALTANAEDPTSLGTY 266
G LEC+V G+P P + WF + I++ D V L A P G Y
Sbjct: 1070 VGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVY 1129
Query: 267 TCEAVNCMGRAYSSSKVHV 285
N +G+A + ++V
Sbjct: 1130 KSVIANKLGKAACYAHLYV 1148
Score = 60.9 bits (141), Expect = 7e-09
Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 32 HHVRAFILNTKSRAGASLDDRF----VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGS 87
+HV A ++ +S GA L+ R +S + L + D G T A N G+
Sbjct: 1285 NHVEAQVV-WRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGT 1343
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
T V LE++ + P F ++D+ V G RF V + + WY++E
Sbjct: 1344 QTCSVTLELA--------EAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVL 1395
Query: 148 LLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
L E+ VS V + + G +TCTA+N+ G SC A L V
Sbjct: 1396 LTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1445
Score = 43.6 bits (98), Expect = 0.001
Identities = 50/203 (24%), Positives = 75/203 (36%), Gaps = 25/203 (12%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
E P+ E+ P L + D+ V + + + E +V W LLEA R +
Sbjct: 1252 EHGPTLEEAPAMLDK-PDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEA-RAGVYE 1309
Query: 159 ----DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
D +C G TCTA N G +CS L + +A + +E++
Sbjct: 1310 LSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELA--EAPRFESIMEDVEV 1367
Query: 215 LLTEQGTVSLECKVVGVPTPVLRWFKDS------------REIKAGDVFALTANAEDPTS 262
E T V G P P + W+KD E + L+ A+D
Sbjct: 1368 GAGE--TARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDG-- 1423
Query: 263 LGTYTCEAVNCMGRAYSSSKVHV 285
G YTC A N G +++ V
Sbjct: 1424 -GVYTCTAQNLAGEVSCKAELAV 1445
Score = 41.1 bits (92), Expect = 0.006
Identities = 34/131 (25%), Positives = 52/131 (39%), Gaps = 3/131 (2%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCX 165
PPTF L D +V+ G + + + V+W RN + + + R + +G
Sbjct: 739 PPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRL 798
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL- 224
G +TC A N G C A L V + + L+ + G ++L
Sbjct: 799 RILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALF 858
Query: 225 ECKVVGVPTPV 235
EC V G PT V
Sbjct: 859 ECLVAG-PTDV 868
Score = 37.5 bits (83), Expect = 0.071
Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 96 VSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVS 155
VSA E P + P F LQ++ V G I ++ +V+W+++ L R+
Sbjct: 583 VSAGEEPL--EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLL 640
Query: 156 IVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+ +G G + TA N G+A+C+A L V
Sbjct: 641 LRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTV 682
Score = 33.1 bits (72), Expect = 1.5
Identities = 30/110 (27%), Positives = 47/110 (42%), Gaps = 5/110 (4%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLG 264
P F L+ ++ G V L+C + P P + W KD +++ L A E T L
Sbjct: 593 PVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLL- 651
Query: 265 TYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG-LSPEPPPIFTRE 313
EA +Y ++ + +G+A+ SL G SP PI + E
Sbjct: 652 --LREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDE 699
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3071
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3129
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3186
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3187 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 88.6 bits (210), Expect = 3e-17
Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N + P G Y+C+A+N G + + V+ + G+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 1457
Query: 295 LKPN 298
PN
Sbjct: 1458 NFPN 1461
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3633
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3634 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3691
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3747
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3170 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3220
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3221 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3278
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 74.5 bits (175), Expect = 5e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 72.9 bits (171), Expect = 2e-12
Identities = 78/298 (26%), Positives = 125/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2301
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2359
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2414
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P + WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2465
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2466 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2518
Score = 71.7 bits (168), Expect = 4e-12
Identities = 65/243 (26%), Positives = 96/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2923 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2975
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +NE+ + IV G G +
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3033
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3152
Query: 291 REG 293
EG
Sbjct: 3153 IEG 3155
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2586
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2587 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2644
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2645 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2704
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2762
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2763 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2814
Query: 347 G 347
G
Sbjct: 2815 G 2815
Score = 70.1 bits (164), Expect = 1e-11
Identities = 67/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2840
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP K + EE+ L+ + + EC G
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI--ECLSSG 2898
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2899 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2958
Query: 282 KVHV 285
VHV
Sbjct: 2959 NVHV 2962
Score = 69.7 bits (163), Expect = 1e-11
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 21/236 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L W
Sbjct: 2173 TCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIW 2230
Query: 239 FKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4076 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4127
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4128 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4180
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4181 NENSQAILPCVADGIPTPAINWKKDN 4206
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3819
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3880 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3934
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3935 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/292 (23%), Positives = 116/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2402
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E +TW+++ + + V I+ G G++TC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2460
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2461 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2518
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2519 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2569
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2570 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2613
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2490
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2548
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2606
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2665
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2666 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2711
Query: 347 GK 348
G+
Sbjct: 2712 GQ 2713
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 2090
Score = 64.5 bits (150), Expect = 5e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3446
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3504
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3562
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3606
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 20/222 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ DTG YT +A+N AG + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD------ELTQLTVIEGN 2212
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
L E + W + +L RV I+ G ++C
Sbjct: 2213 LISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSCV 2270
Query: 182 AENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W K
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 241 DSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
D IKA V L + G Y C AVN G
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3483 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3536
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3594
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3595 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3652
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3700
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3917
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3918 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3969
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3970 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4025
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4026 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4073
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4074 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4117
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/243 (20%), Positives = 93/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P +++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4284
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 4285 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 4340
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4341 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4397
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4398 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4444
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4485
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4003
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4061
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4062 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4117
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4118 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4177
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4178 YTVNENSQAILP 4189
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3359 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3410
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3468
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3469 WLRDGQPL 3476
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3723
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3724 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3778
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3834
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3835 INWRKN 3840
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/251 (23%), Positives = 96/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 1042 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 1096
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 1157 GNVTQAVKLNV 1167
Score = 39.5 bits (88), Expect = 0.018
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL----- 4363
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4364 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4418
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4475 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 54 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 109
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 110 REGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 167
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 168 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 224
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 225 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 271
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 618 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 671
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 672 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 729
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 730 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 785
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 786 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 840
Score = 79.8 bits (188), Expect = 1e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 148 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 207
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 208 ----TLTCDATGIPPPT---IAWLKNHKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 258
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 259 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 316
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 317 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 364
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 1056 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 1113
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 1114 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 1165
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 1166 LSSGSL---QITFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 1218
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 1219 NENSQAILPCVADGIPTPAINWKKDN 1244
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 806 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 857
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 858 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 917
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 918 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 972
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 973 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 1022
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 431 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 484
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 485 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 542
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 543 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 600
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 601 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 644
Score = 60.9 bits (141), Expect = 7e-09
Identities = 52/196 (26%), Positives = 82/196 (41%), Gaps = 12/196 (6%)
Query: 107 PPTFLR-RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
PP+ + + ++LTV V E+ ++W +NE+ + IV G
Sbjct: 1 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL-- 58
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G +TC A N G + L V VP + K + E L + +GT VSL
Sbjct: 59 QIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSL 117
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA 277
E + VP PV+ W+K+ R I + A+ + + + G Y C A+N GR
Sbjct: 118 EXESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRD 177
Query: 278 YSSSKVHVVGRASREG 293
+ ++V S EG
Sbjct: 178 DKNFHLNVYVPPSIEG 193
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 521 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 574
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 575 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 632
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 633 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 690
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 691 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 738
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 899 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 955
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 956 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 1007
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 1008 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 1063
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 1064 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 1111
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 1112 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 1155
Score = 59.7 bits (138), Expect = 2e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 990 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 1041
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 1042 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 1099
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 1100 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 1155
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 1156 AIVESIRQRVLSSGSLQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 1215
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 1216 YTVNENSQAILP 1227
Score = 59.3 bits (137), Expect = 2e-08
Identities = 70/282 (24%), Positives = 104/282 (36%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 1271 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 1322
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G
Sbjct: 1323 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAI 1378
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 1379 GFVYVKEPPVFKGDYPSHWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 1435
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 1436 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 1482
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 1483 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 1523
Score = 51.6 bits (118), Expect = 4e-06
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L L D
Sbjct: 337 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 396
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 397 SINIECRA------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 448
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 449 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 506
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 507 WLRDGQPL 514
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 710 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 761
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 762 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 816
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 817 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 872
Query: 236 LRWFKD 241
+ W K+
Sbjct: 873 INWRKN 878
Score = 38.7 bits (86), Expect = 0.031
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 1347 GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWIEPL----- 1401
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 1402 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 1456
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 1457 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 1512
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 1513 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 1554
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 90.2 bits (214), Expect = 9e-18
Identities = 68/227 (29%), Positives = 98/227 (43%), Gaps = 18/227 (7%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L + A+ D G YT A N AG + L V S D + L + V
Sbjct: 3017 GGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSES----LSVVNV 3072
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ GT E + +TWY+N R + E+ V I+ DG G++
Sbjct: 3073 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML--HIKKAEVSDTGQYV 3130
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A NV GR + HLNV VP + + PE E+ + T V+L C G+P P + W
Sbjct: 3131 CRAINVAGRDDKNFHLNVYVPPSIEGPE--REV-IVETISNPVTLTCDATGIPPPTIAWL 3187
Query: 240 KDSREIKAGD---VFALTANAE------DPTSLGTYTCEAVNCMGRA 277
K+ + I+ D V L+ ++ + G YTC A N G+A
Sbjct: 3188 KNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3234
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/232 (26%), Positives = 98/232 (42%), Gaps = 17/232 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 1281
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ +G+ G + C
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEGTLL--VIASVTPYDNGEYICV 1339
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 1340 AVNEAGTTERKYNLKVHVPPVIKDKEQVSNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 1397
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ ++ N + P G Y+C+A+N G + + V+
Sbjct: 1398 NVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 80.2 bits (189), Expect = 1e-14
Identities = 65/252 (25%), Positives = 103/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 1496 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 1554
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ +TR L +TWY++ + ++ + + + G +
Sbjct: 1555 TDISVLINSLIKLECKTRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 1606
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LEC
Sbjct: 1607 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECNA 1665
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D F + A + G Y C A + G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNFRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 1726 EVDVLVPPAIEG 1737
Score = 80.2 bits (189), Expect = 1e-14
Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 21/235 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +STA+ DTG YT AS+ AG D + V + +G D P +D+TV
Sbjct: 3581 GGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP------RDITV 3634
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + +TW RN RL RV I+ G + +T
Sbjct: 3635 LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYL--QINNADLGDTANYT 3692
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N+ G+ + L V VP K + +L + TV LEC GVPTP + W
Sbjct: 3693 CVASNIAGKTTREFILTVNVPPNIKGG---PQSLVILLNKSTV-LECIAEGVPTPRITWR 3748
Query: 240 KDSREIKAGDV-FALTAN------AEDPTSLGTYTCEAVNCMG--RAYSSSKVHV 285
KD + +++ N + T G Y C A N G R +VHV
Sbjct: 3749 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3803
Score = 79.0 bits (186), Expect = 2e-14
Identities = 63/228 (27%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G L + A DTG Y +A N AG D L V S G + + + +
Sbjct: 3111 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3170
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXG 176
T T I T + W +N +R+ ++ V I+ GS G
Sbjct: 3171 ----TLTCDATGIPPPT---IAWLKNYKRIENSDSLEVRILSGGSKL--QIARSQHSDSG 3221
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
+TC A N+ G+A L++ VP + E ++ LL E V L C G+PTP++
Sbjct: 3222 NYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLI 3279
Query: 237 RWFKDSREIKAGDVFALTANAEDPT---------SLGTYTCEAVNCMG 275
+W KD + I +G+ + +A T G YTC A N G
Sbjct: 3280 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3327
Score = 75.4 bits (177), Expect = 3e-13
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVSNVSVL 1373
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 1374 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL--KLFRATPEDAGRYSC 1431
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F +E+ +L V+LEC+V G P P + WFK
Sbjct: 1432 KAINIAGTSQKYFNIDVLVPPTIIGTNFPKEVSVVLNRD--VALECQVKGTPFPDIHWFK 1489
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 1490 DGKPLFLGD 1498
Score = 71.7 bits (168), Expect = 4e-12
Identities = 78/298 (26%), Positives = 124/298 (41%), Gaps = 36/298 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES--PSGEDPPTFLRRLQD 116
+GG +L +S A D +Y+ ASN AG+ L+V + SG P +
Sbjct: 2250 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT-------E 2302
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+ V G E+ VTW ++ L++A+ V I+ +G G
Sbjct: 2303 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL--QLKNIHVSDTG 2360
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKA----YKRPEFVEELRALLTEQGTVSLECKVVGVP 232
R+ C A NV G L+V P + ++ PE + + E+ +VSL C+ G+P
Sbjct: 2361 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS-----VVEKNSVSLTCEASGIP 2415
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
P WFKD + + + + + T T E Y+ VV A+ E
Sbjct: 2416 LPSTTWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAG----QYTC----VVRNAAGE 2466
Query: 293 GSLKPNSSGLSPEPPPIFTRE--LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ GLS PP E LED V+ + TL+C++ P P + W+ K+G+
Sbjct: 2467 ---ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP-EITWH-KDGQ 2519
Score = 70.9 bits (166), Expect = 6e-12
Identities = 70/301 (23%), Positives = 119/301 (39%), Gaps = 27/301 (8%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ + TG YT AS+ AG + L V + +G +D+T
Sbjct: 2531 SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDG---NPEDVT 2587
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + + T + E S +TW+++ L + I+ G GR+
Sbjct: 2588 VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTL--QILNAQEDNAGRY 2645
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEF----VEELRALLTEQGTVSLECKVVGVPTP 234
+C A N G + V +P + + + + T++LEC+ +P+
Sbjct: 2646 SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSA 2705
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
L W+KD + +K+ D + AN + G YTC A N G V++
Sbjct: 2706 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNI-- 2763
Query: 288 RASREGSLKPNSSGLSPEPPPIFT-RELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+ P+ L + T R E + V I P +L C+ P P ++ WY K+
Sbjct: 2764 ------QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP-PPTLTWY-KD 2815
Query: 347 G 347
G
Sbjct: 2816 G 2816
Score = 69.7 bits (163), Expect = 1e-11
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 18/243 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+ G L + + D G Y A N AGS L V S G + ++LT
Sbjct: 2924 SNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-------KSENLT 2976
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V V E+ ++W +N + + IV G G +
Sbjct: 2977 VVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTL--QIIRAKVSDGGEY 3034
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLR 237
TC A N G + L V VP + K + E L + +GT VSLEC+ VP PV+
Sbjct: 3035 TCIAINXAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVPPPVIT 3093
Query: 238 WFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W+K+ R I + A+ + + + G Y C A+N GR + ++V S
Sbjct: 3094 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS 3153
Query: 291 REG 293
EG
Sbjct: 3154 IEG 3156
Score = 68.5 bits (160), Expect = 3e-11
Identities = 66/244 (27%), Positives = 98/244 (40%), Gaps = 23/244 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE---DPPTFL---R 112
A G L + A+ DTG YT ASN AG D + +V+ + PS + + L R
Sbjct: 2726 ANGHTLQIKEAQISDTGRYTCVASNIAGED--ELDFDVNIQVPPSFQKLWEIGNMLDTGR 2783
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
+ V + E ++ +TWY++ L +++V I+ G
Sbjct: 2784 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVL--QIPRAKV 2841
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVG 230
GR+TC A N G S + VLVP + + EE+ L+ + + EC G
Sbjct: 2842 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALI--ECLSSG 2899
Query: 231 VPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRA--YSSS 281
P P W KD + + D +N T +G Y C A N G A Y +
Sbjct: 2900 SPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNL 2959
Query: 282 KVHV 285
VHV
Sbjct: 2960 NVHV 2963
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
FI K + R + +GG L +S A D G Y A N AG+ +++L V
Sbjct: 4019 FITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4076
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
PP L++ + V E +TW+++ R ++E+ R +
Sbjct: 4077 QV--------PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV 4128
Query: 157 VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL 216
+ GS G +TC A NV G +S S L V VP + E +
Sbjct: 4129 LSSGSL---QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG----HYTV 4181
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKDS 242
E L C G+PTP + W KD+
Sbjct: 4182 NENSQAILPCVADGIPTPAINWKKDN 4207
Score = 67.7 bits (158), Expect = 6e-11
Identities = 60/230 (26%), Positives = 90/230 (39%), Gaps = 21/230 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + +A DTG Y A+NAAG+D R+ L+V PP+ ++TV V
Sbjct: 3769 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV--------PPSIAPGPTNMTVIVNV 3820
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+T E + + W +N L + + R S + CT
Sbjct: 3821 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3880
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G + L V VP P +E L+T+ + C GVP P + W K+
Sbjct: 3881 NGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNG 3935
Query: 243 -REIKAGDVFALTAN------AEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
R + GD + + ++ A G YTC A N G A+ +HV
Sbjct: 3936 IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3985
Score = 65.3 bits (152), Expect = 3e-10
Identities = 79/302 (26%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L + D G YT NAAG + L V GE+ L+D+
Sbjct: 2438 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN------TLEDVK 2491
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
VK E+ + ++TW+++ + L E E I+ G F GR+
Sbjct: 2492 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL--QITNVQVPHTGRY 2549
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYK---RPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
TC A + G S S LNV V E++ +L SL C+ P
Sbjct: 2550 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVIL--NSPTSLVCEAYSYPPAT 2607
Query: 236 LRWFKD------SREIK--AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV-V 286
+ WFKD +R I+ G NA++ + G Y+C A N G +V V +
Sbjct: 2608 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA-GRYSCVATNEAGEMIKHYEVKVYI 2666
Query: 287 GRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKE 346
+G L GLSP +E++ +++ TL C+ P S+ WY K+
Sbjct: 2667 PPIINKGDLW--GPGLSP-------KEVK---IKVNNTLTLECEAYAIP-SASLSWY-KD 2712
Query: 347 GK 348
G+
Sbjct: 2713 GQ 2714
Score = 64.5 bits (150), Expect = 5e-10
Identities = 70/292 (23%), Positives = 115/292 (39%), Gaps = 34/292 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + DTG Y A N AG + L V A S G R ++++V
Sbjct: 2349 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNH-----RSPENISVVEKN 2403
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E TW+++ + + V I+ G G++TC
Sbjct: 2404 SVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGGRML--RLMQTTMEDAGQYTCVVR 2461
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G L+VLVP +E+++ + E+ +V+L C+V G P P + W KD +
Sbjct: 2462 NAAGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQ 2519
Query: 244 EIK--------AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ +G F N + P + G YTC A + G S ++V +
Sbjct: 2520 PLQEDEAHHIISGGRFLQITNVQVPHT-GRYTCLASSPAGHKSRSFSLNVF--------V 2570
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
P +G+ + P ED V + P +L C+ P P ++ W+ K+G
Sbjct: 2571 SPTIAGVGSDGNP------EDVTVILNSPTSLVCEAYSYP-PATITWF-KDG 2614
Score = 64.1 bits (149), Expect = 7e-10
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 23/238 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+ V L ++ D G Y A ++AG+ A+ +VS +PP ++ +
Sbjct: 477 KESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS--------EPPPVIQVPNN 528
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNER--RLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+TV G R IIS+ + +TW RN+R RL E R+ + + S
Sbjct: 529 VTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSL---ELKSVKFND 585
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G + C + GG ++ S L V P V T VS+ C G P P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVT----VMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 235 VLRWFKDSREIKAGDVFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W + I + +T++ P G Y C A N G +S + +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI 699
Score = 63.7 bits (148), Expect = 9e-10
Identities = 59/237 (24%), Positives = 98/237 (41%), Gaps = 22/237 (9%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++ + DTG YT A NAAG + L V PP + Q+++
Sbjct: 2063 SGGRILALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 2114
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 2115 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 2172
Query: 179 TCTAENVGGRA-SCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
TC A NV G+ + ++N+ VP + + +L + E +SL C+ G+P P L
Sbjct: 2173 TCEATNVAGKTEKKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLI 2230
Query: 238 WFKDSREI---KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W K + G V L+ + + + Y+C A N G A + V
Sbjct: 2231 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2287
Score = 62.9 bits (146), Expect = 2e-09
Identities = 61/227 (26%), Positives = 88/227 (38%), Gaps = 23/227 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
A G + + A+ D VYT ASN AG D L+V A P D +++T
Sbjct: 3394 AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA---PPNMDNS---MGTEEIT 3447
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V G+ T + + W R+ + L +++ G G++
Sbjct: 3448 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKY 3505
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
TC A N G S L VL P E EE+ ++ + L C G+P P + W
Sbjct: 3506 TCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIV--NNPLELTCIASGIPAPKMTW 3563
Query: 239 FKDSREIK---------AGDVFAL-TANAEDPTSLGTYTCEAVNCMG 275
KD R + G+V + TA ED G YTC A + G
Sbjct: 3564 MKDGRPLPQTDQVQTLGGGEVLRISTAQVED---TGRYTCLASSPAG 3607
Score = 62.5 bits (145), Expect = 2e-09
Identities = 59/228 (25%), Positives = 86/228 (37%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1930
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ L + ++ + G G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQII--DIESAQISDAGI 1988
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1989 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 2044
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSTQISDT--GRYTCVAVNAAG 2090
Score = 62.1 bits (144), Expect = 3e-09
Identities = 63/281 (22%), Positives = 111/281 (39%), Gaps = 32/281 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + + D G Y S+ GS A V L V ++PP ++ + G+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV--------QEPPKVTVMPKNQSFTGGS 627
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+ W N+ ++ + R + DG+ F G C A
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYG---CLAS 684
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDS 242
N G ++ L + + P+ + LL G ++ +ECK G+P P ++WFK
Sbjct: 685 NSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSSG 301
E++ + DP LG + + Y+ ++ GRA+ + +L S
Sbjct: 740 LELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-- 791
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
PP+F +E D + I TL C + P P ++ W
Sbjct: 792 -----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 826
Score = 61.7 bits (143), Expect = 4e-09
Identities = 52/243 (21%), Positives = 94/243 (38%), Gaps = 18/243 (7%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + A D G Y+ +A N AG+ ++V + G + P ++++V
Sbjct: 1413 GKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------KEVSVV 1466
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ ++ + + W+++ + L + V ++ G GR+
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQ 1524
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
CT N G+ + L + +P + K ++ L+ + LECK G+P P + W+
Sbjct: 1525 CTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECKTRGLPMPAITWY 1582
Query: 240 KDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
KD + I + + + TYTC N G A S V V E
Sbjct: 1583 KDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIE 1642
Query: 293 GSL 295
G+L
Sbjct: 1643 GNL 1645
Score = 60.5 bits (140), Expect = 9e-09
Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 19/229 (8%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
T G+ L + A T D+G YT ASN AG + L+V +G + +
Sbjct: 3484 TVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE------EHE 3537
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+++V V K+TW ++ R L + ++V + G
Sbjct: 3538 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL--RISTAQVEDT 3595
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC A + G + V VP + ++ L Q V+LECK VP PV
Sbjct: 3596 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPV 3653
Query: 236 LRWFKDSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+ W ++ ++A G + L N D YTC A N G+
Sbjct: 3654 ITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVASNIAGK 3701
Score = 60.5 bits (140), Expect = 9e-09
Identities = 70/282 (24%), Positives = 105/282 (37%), Gaps = 29/282 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G YT A+NAAG DT V L V PTF D+++ G + R +
Sbjct: 4234 DSGFYTCVANNAAGEDTHTVSLTVHV--------LPTFTELPGDVSLNKGEQLRLSCKAT 4285
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
K+TW N ++ A S+ G + CTAEN G +
Sbjct: 4286 GIPLPKLTWTFN-NNIIPAHFDSVNGHSEL---VIERVSKEDSGTYVCTAENSVGFVKAT 4341
Query: 193 AHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA 252
+ V P +K + L G L C+V G PTP ++W + +I+
Sbjct: 4342 GFVYVKEPPVFKGDYPSNWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR 4398
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
N SL Y VN Y+ A+ E + S L+ + PPI T
Sbjct: 4399 QLGNG----SLAIY--GTVNEDAGDYTCV-------ATNEAGVVERSMSLTLQSPPIITL 4445
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E + + L+CQ P P ++ W + + +R
Sbjct: 4446 EPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDR 4486
Score = 60.1 bits (139), Expect = 1e-08
Identities = 60/236 (25%), Positives = 91/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A+N AG+ T V+L V PP R + L V+VG
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 1186
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 1243
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 1244 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 1302
Query: 241 DSREIKAGDV--------FALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ + L + P G Y C AVN G R Y + KVHV
Sbjct: 1303 NGRELTGREPGISILEEGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 1357
Score = 60.1 bits (139), Expect = 1e-08
Identities = 74/286 (25%), Positives = 111/286 (38%), Gaps = 30/286 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + DT Y +N AG D V L V S + E P FL + V T
Sbjct: 3862 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE-PTDFL--VTKHAPAVIT 3918
Query: 124 RTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T V S + W +N RLL + I+ G+ GR+TC A
Sbjct: 3919 CTASGVPFPS-----IHWTKNGIRLLPRGDGYRILSSGAI---EILATQLNHAGRYTCVA 3970
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G A L+V P + P+ EL +L + L C+ G P+P + W K+
Sbjct: 3971 RNAAGSAHRHVTLHVHEPPVIQ-PQ-PSELHVILNNP--ILLPCEATGTPSPFITWQKEG 4026
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGL 302
+ N S G AV Y + G A G +K L
Sbjct: 4027 INVNTSG-----RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL--GKIK-----L 4074
Query: 303 SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ + PP+ + L++ + + +P TLSC+ P P + W+ K+G+
Sbjct: 4075 NVQVPPVISPHLKEYVIAVDKPITLSCEADGLP-PPDITWH-KDGR 4118
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 717
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 718 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 776 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 830
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 886
Score = 59.3 bits (137), Expect = 2e-08
Identities = 59/263 (22%), Positives = 105/263 (39%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 1772 GQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV------- 1824
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 1825 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 1882 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1937
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+ + + + + G Y C A+N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1998 GATELFYSLQVHVAPSISGSNNM 2020
Score = 59.3 bits (137), Expect = 2e-08
Identities = 60/223 (26%), Positives = 86/223 (38%), Gaps = 21/223 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
L + A+ DTG YT +A+N AG ++ + + + G D L LTV G
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKKNYNVNIWVPPNIGGSD------ELTQLTVIEG 2212
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
L E + W + +L RV I+ G ++C
Sbjct: 2213 NLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL--QISIAEKSDAALYSC 2270
Query: 181 TAENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
A NV G A +L V + P E+ ++T ++SLEC+V G+P P + W
Sbjct: 2271 VASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI--IVTRGKSISLECEVQGIPPPTVTWM 2328
Query: 240 KDSRE-IKAGDV------FALTANAEDPTSLGTYTCEAVNCMG 275
KD IKA V L + G Y C AVN G
Sbjct: 2329 KDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2371
Score = 58.8 bits (136), Expect = 3e-08
Identities = 66/252 (26%), Positives = 95/252 (37%), Gaps = 25/252 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ + + G YT A NAAGS V L V +PP + +L V +
Sbjct: 3953 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV--------HEPPVIQPQPSELHVILNN 4004
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
E + +TW + + + R V G + C A+
Sbjct: 4005 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGL--QISRAVREDAGTYMCVAQ 4062
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G A LNV VP P E + A+ ++L C+ G+P P + W KD R
Sbjct: 4063 NPAGTALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGR 4118
Query: 244 EI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSK--VHVVGR-ASREG- 293
I + +L P G YTC A N G + +S+K VHV R S EG
Sbjct: 4119 AIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH 4178
Query: 294 -SLKPNSSGLSP 304
++ NS + P
Sbjct: 4179 YTVNENSQAILP 4190
Score = 58.4 bits (135), Expect = 4e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 1744
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGL 1802
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 1859
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 49.6 bits (113), Expect = 2e-05
Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 11/188 (5%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG-EDPPTFLRRLQDL 117
A G L + A T DTG YT A+N AG + L V + G +D L D
Sbjct: 3300 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDT 3359
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
++ + R + ++ W +N L + + ++ G
Sbjct: 3360 SINIECRX------TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVI--RIVRAQVSDVAV 3411
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+TC A N G + +L V P EE+ L + + S+ C G P P +
Sbjct: 3412 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMA 3469
Query: 238 WFKDSREI 245
W +D + +
Sbjct: 3470 WLRDGQPL 3477
Score = 48.8 bits (111), Expect = 3e-05
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L ++ A GDT YT ASN AG T L V+ PP Q L
Sbjct: 3673 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV--------PPNIKGGPQSLV 3724
Query: 119 VKVGTRTRFLVEIISS--TECKVTWYRNERRLL-EAERVSIVRDGSFFCXXXXXXXXXXX 175
+ + T ++E I+ ++TW ++ L R SI+ +G
Sbjct: 3725 ILLNKST--VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFL---HIQSAHVTDT 3779
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+ C A N G L V VP + + ++ Q T L C+ G+P P
Sbjct: 3780 GRYLCMATNAAGTDRRRIDLQVHVPPSIAPGP--TNMTVIVNVQTT--LACEATGIPKPS 3835
Query: 236 LRWFKD 241
+ W K+
Sbjct: 3836 INWRKN 3841
Score = 46.8 bits (106), Expect = 1e-04
Identities = 56/210 (26%), Positives = 81/210 (38%), Gaps = 28/210 (13%)
Query: 141 WYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
W +N LL+ +++ DGS G +TC A NV G + + + V V
Sbjct: 924 WIKNSAMLLQNPYITVRSDGSLHIERVQLQDG---GEYTCVASNVAGTNNKTTSVVVHV- 979
Query: 201 KAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFK-------DSREIKAGDVFA 252
P + L T +G V+L CK G P P + W K S + AG +
Sbjct: 980 ----LPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS 1035
Query: 253 LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTR 312
L + + G Y C A N G A ++ V R G L+ GLS + P +
Sbjct: 1036 LYVVSPEGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLR----GLSQDKPVEIS- 1090
Query: 313 ELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
V E TL C++ P P + W
Sbjct: 1091 ------VLAGEEVTLPCEVKSLP-PPIITW 1113
Score = 46.0 bits (104), Expect = 2e-04
Identities = 60/254 (23%), Positives = 95/254 (37%), Gaps = 35/254 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 932 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 981
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 1041
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT------ 221
G + CTA N G A L V Y RP +LR L ++
Sbjct: 1042 EGEES---GEYVCTATNTAGYAKRKVQLTV-----YVRPRVFGDLRGLSQDKPVEISVLA 1093
Query: 222 ---VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAV 271
V+L C+V +P P++ W K+++ I F + + E TS G Y C A
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAT 1153
Query: 272 NCMGRAYSSSKVHV 285
N G + K++V
Sbjct: 1154 NIAGNVTQAVKLNV 1167
Score = 40.3 bits (90), Expect = 0.010
Identities = 47/222 (21%), Positives = 74/222 (33%), Gaps = 20/222 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G L + D+G Y A N+ G A + V G+ P ++ L
Sbjct: 4310 GHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPVFKGDYPSNWIEPL----- 4364
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G E+ + W R + + R+ + +GS G +T
Sbjct: 4365 --GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYT 4419
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
C A N G S L + P +E + ++ G + L C+ G P P + W
Sbjct: 4420 CVATNEAGVVERSMSLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWS 4475
Query: 240 KDSREIKAGD-VFALTANA-----EDPTSLGTYTCEAVNCMG 275
+ I D V L+ N+ + C A N MG
Sbjct: 4476 RQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4517
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens
cDNA FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 88.2 bits (209), Expect = 4e-17
Identities = 65/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVG 122
L++ A D G+YT A+N AG+D + L V +E P+ ED P + Q+
Sbjct: 297 LSIDQATPSDAGIYTCVATNIAGTDETEITLHV--QEPPTVEDLEPPYNTTFQERV--AN 352
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
R F + + + W N R L E +SI+ DG+ G + C
Sbjct: 353 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL--VIASVTPYDNGEYICV 410
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
A N G +L V VP K E V + LL + +L C+V G P+P++ W+KD
Sbjct: 411 AVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKD 468
Query: 242 SREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ ++ N P G Y+C+A+N G + + V+ + G+
Sbjct: 469 NVQVTESSTIQTVNNGRILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGT 528
Query: 295 LKPN 298
PN
Sbjct: 529 NFPN 532
Score = 79.0 bits (186), Expect = 2e-14
Identities = 65/252 (25%), Positives = 102/252 (40%), Gaps = 17/252 (6%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D V + G V L + AR D G Y SNAAG ++L + S G +
Sbjct: 567 LGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVT 625
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
T + L + +K+ TR L +TWY++ + ++ + + + G +
Sbjct: 626 TDISVLINSLIKLECETRGL------PMPAITWYKDGQPIMSSSQALYIDKGQYL--HIP 677
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
+TC NV G A S H++V VP + L + +++LECK
Sbjct: 678 RAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEG-NLATPLNKQVVIAHSLTLECKA 736
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSS 281
G P+P+L W KD +KA D + A + G Y C A + G
Sbjct: 737 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 796
Query: 282 KVHVVGRASREG 293
+V V+ + EG
Sbjct: 797 EVDVLVPPAIEG 808
Score = 74.1 bits (174), Expect = 7e-13
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L +++ D G Y A N AG+ + L+V P +D ++ +++V
Sbjct: 391 GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVP--PVIKDK----EQVTNVSVL 444
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+ T E+ + + WY++ ++ E+ + V +G GR++C
Sbjct: 445 LNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGRIL--KLFRATPEDAGRYSC 502
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N+ G + +++VLVP F E+ +L V+LEC+V G P P + WFK
Sbjct: 503 KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFK 560
Query: 241 DSREIKAGD 249
D + + GD
Sbjct: 561 DGKPLFLGD 569
Score = 64.9 bits (151), Expect = 4e-10
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 24/228 (10%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
++ G L ++ D G YT A+NAAG ++L V E PS ED L
Sbjct: 948 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNE---- 1001
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
TV V + + + +TWY++ R L + ++ + G G
Sbjct: 1002 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII--DIESAQISDAGI 1059
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G L V V + + + V LEC+ G+P P L
Sbjct: 1060 YKCVAINSAGATELFYSLQVHVAPSISGSNNM----VAVVVNNPVRLECEARGIPAPSLT 1115
Query: 238 WFKDSREIKA----------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
W KD + + G + ALT+ T G YTC AVN G
Sbjct: 1116 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT--GRYTCVAVNAAG 1161
Score = 62.1 bits (144), Expect = 3e-09
Identities = 60/263 (22%), Positives = 106/263 (40%), Gaps = 27/263 (10%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G +D+R G +L ++ A+ +TG+Y A+N AG + V
Sbjct: 843 GQLVDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKEEFEVTVHV------- 895
Query: 106 DPPTFLRRLQDLTVKVGTRTR-FLVEIISS--TECKVTWYRNERRLLEAE-RVSIVRDGS 161
PPT + L+ +V + + ++ I++ +TW ++++ + A+ + I G
Sbjct: 896 -PPTI--KSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 952
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
GR+TC A N G L+V P + + + + L +
Sbjct: 953 VL--QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLE--DAGKMLNETVLVSNP 1008
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCM 274
V LECK G P PV+ W+KD+R + + + + G Y C A+N
Sbjct: 1009 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1068
Query: 275 G--RAYSSSKVHVVGRASREGSL 295
G + S +VHV S ++
Sbjct: 1069 GATELFYSLQVHVAPSISGSNNM 1091
Score = 60.1 bits (139), Expect = 1e-08
Identities = 61/236 (25%), Positives = 90/236 (38%), Gaps = 27/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
+ ++ RT D+G+Y A N AG+ T V+L V PP R + L V+VG
Sbjct: 206 MKITETRTSDSGMYLCVAINIAGNVTQAVKLNVHV--------PPKIQRGPKHLKVQVGQ 257
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
R + +TW + L++ E DG+ G +TC A
Sbjct: 258 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL---SIDQATPSDAGIYTCVA 314
Query: 183 ENVGGRASCSAHLNVLVPKAYK--RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
N+ G L+V P + P + + + Q + C G P P ++W
Sbjct: 315 TNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLH 373
Query: 241 DSREIKA--------GDVFALTANAEDPTSLGTYTCEAVNCMG---RAYSSSKVHV 285
+ RE+ D L + P G Y C AVN G R Y + KVHV
Sbjct: 374 NGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHV 428
Score = 59.3 bits (137), Expect = 2e-08
Identities = 50/240 (20%), Positives = 92/240 (38%), Gaps = 18/240 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G Y+ +A N AG+ ++V + G + P +++V +
Sbjct: 487 LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPN------EVSVVLNR 540
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
++ + + W+++ + L + V ++ G GR+ CT
Sbjct: 541 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL--HLKNARRNDKGRYQCTV 598
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G+ + L + +P + K ++ L+ + LEC+ G+P P + W+KD
Sbjct: 599 SNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPMPAITWYKDG 656
Query: 243 REIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
+ I + + + TYTC N G A S V V EG+L
Sbjct: 657 QPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNL 716
Score = 57.6 bits (133), Expect = 6e-08
Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
EAGG +L + +A+ D G Y A++ AG + ++V + G D ++
Sbjct: 762 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSY------F 815
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
V V + S + W ++ + + E + I+ +G G
Sbjct: 816 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKL--VIAQAQVSNTGL 873
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G + V VP K E ++ + V+L+C G+P P +
Sbjct: 874 YRCMAANTAGDHKEEFEVTVHVPPTIKSSGLSER---VVVKYKPVALQCIANGIPNPSIT 930
Query: 238 WFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W KD + + +G V + + G YTC A N G ++HV
Sbjct: 931 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQQHIQLHV 986
Score = 56.4 bits (130), Expect = 1e-07
Identities = 55/222 (24%), Positives = 81/222 (36%), Gaps = 20/222 (9%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G + + +A+ D G+Y A N+AG+ L+V S SG + + V
Sbjct: 1044 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSN--------NMVAVV 1095
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
V R E +TW ++ + V G GR+TC
Sbjct: 1096 VNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT-GRYTC 1154
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N G L V VP E + + L+++ V L C+ +P P L W K
Sbjct: 1155 VAVNAAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLK 1210
Query: 241 DSREIKAGDVFALTAN-----AEDP--TSLGTYTCEAVNCMG 275
D + +++ N ED G YTCEA N G
Sbjct: 1211 DGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 47.6 bits (108), Expect = 7e-05
Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 10/129 (7%)
Query: 59 AGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT 118
+GG L +++A+ DTG YT A NAAG + L V PP + Q+++
Sbjct: 1134 SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV--------PPNIMGEEQNVS 1185
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V + L + + +TW ++ LL+ +SI + S GR+
Sbjct: 1186 VLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVL--KIEDAQVQDTGRY 1243
Query: 179 TCTAENVGG 187
TC A NV G
Sbjct: 1244 TCEATNVAG 1252
Score = 46.8 bits (106), Expect = 1e-04
Identities = 59/251 (23%), Positives = 97/251 (38%), Gaps = 29/251 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 3 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 52
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 53 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 112
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 113 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 167
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A+N
Sbjct: 168 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAINIA 227
Query: 275 GRAYSSSKVHV 285
G + K++V
Sbjct: 228 GNVTQAVKLNV 238
>AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform
protein.
Length = 2154
Score = 82.2 bits (194), Expect = 3e-15
Identities = 69/244 (28%), Positives = 106/244 (43%), Gaps = 31/244 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
R+ +S R D G YT AG + + V L V+A E PP L+ LQ +TV+ G
Sbjct: 760 RMFISETRQSDAGEYTF----VAGRNRSSVTLYVNAPE------PPQVLQELQPVTVQSG 809
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF I + K++WY+ E+ L + + DG + +TC A
Sbjct: 810 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 869
Query: 183 ENVGGRASCSAHLNVLVPKAYK--------RPEFVEELRALLTEQG-TVSLECKVVGVPT 233
+N G A+ SA L+V VP+ P + L+ +T +G +C+V G
Sbjct: 870 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 929
Query: 234 PVLRWFKDSREIKAGDVFALTANAED----------PTSLGTYTCEAVNCMGRAYSSSKV 283
V W+ ++IK F +T ED P GTYT A N +G+ S++ +
Sbjct: 930 KV-SWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 987
Query: 284 HVVG 287
+ G
Sbjct: 988 SLEG 991
Score = 62.9 bits (146), Expect = 2e-09
Identities = 64/258 (24%), Positives = 103/258 (39%), Gaps = 43/258 (16%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEE--SPSGEDP---PTFLRRLQDLTVKVGTRTRF 127
D VYT +A N G T L V E SP E P P + LQD G RF
Sbjct: 861 DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF 920
Query: 128 LVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG 187
+ S T+ KV+WY ++++ + + + + G +T A N G
Sbjct: 921 QCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG 979
Query: 188 RASCSAHLN-----------------VLVPKAYKR------PEFVEELRALLTEQG-TVS 223
+ S +A+L+ V + ++K+ P F++ L +L G TV
Sbjct: 980 QVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVR 1039
Query: 224 LECKVVGVPTPVLRWFKDSR------------EIKAGDVFALTANAEDPTSLGTYTCEAV 271
+V G+P P ++WF + + E G L +A + G Y+C+A
Sbjct: 1040 FHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHA-GQYSCKAA 1098
Query: 272 NCMGRAYSSSKVHVVGRA 289
N G A ++ + V +A
Sbjct: 1099 NSAGEATCAATLTVTPKA 1116
Score = 62.1 bits (144), Expect = 3e-09
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P F++ + + + +G V +I + K+ W+ N L + V DG
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNV--------------LVPKAYKR------PE 207
G +TC A N G+ CSA+L + V K+ ++ P
Sbjct: 1244 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 1303
Query: 208 FVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKDSREIKAGDVFALTAN--------AE 258
F++EL+ + QG ++ E VVG P P + WFK+++++ + + N
Sbjct: 1304 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 1363
Query: 259 DP--TSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
DP G Y C+A N +G + ++++ V+ + + P + +PE P F
Sbjct: 1364 DPQREDSGLYICKAENMLGESTCAAELLVL-LEDTDMTDTPCKAKSTPEAPEDF 1416
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 7/149 (4%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGD-TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
D++F ++ L + T D G Y +A N +G +L V +P
Sbjct: 2011 DEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP------ 2064
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
R+++ L V +G +F EI S+ + W++ R + E+++ SI
Sbjct: 2065 VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEIL 2124
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TC A N G SC+A L V
Sbjct: 2125 RTQVVDCGEYTCKASNEYGSVSCTATLTV 2153
Score = 55.2 bits (127), Expect = 3e-07
Identities = 75/315 (23%), Positives = 123/315 (39%), Gaps = 41/315 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+ DR +E RL + + R D G YT+ AG + + +L V G D
Sbjct: 655 ITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV----VAGGNVSTAKLFV------EGRD-- 702
Query: 109 TFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRN--ERRLLEAERVSIVRDGSFFCX 165
+R ++ V+V + R +VE ++ + WY++ E ER V +
Sbjct: 703 VRIRSIKK-EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM 761
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G +T V GR S L V P+ P+ ++EL+ + + G +
Sbjct: 762 FISETRQSDAGEYTF----VAGRNRSSVTLYVNAPEP---PQVLQELQPVTVQSGKPARF 814
Query: 226 CKVV-GVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
C V+ G P P + W+K+ + + G + L P YTCEA N G
Sbjct: 815 CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 874
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPP 335
A +S+ + V + P+ P PP L+D +P C+ V
Sbjct: 875 VATTSASLSV----EVPEVVSPDQE--MPVYPPAIITPLQDTVTSEGQPARFQCR--VSG 926
Query: 336 WPRSVVWYNKEGKVE 350
V WY+K+ K++
Sbjct: 927 TDLKVSWYSKDKKIK 941
Score = 51.6 bits (118), Expect = 4e-06
Identities = 48/173 (27%), Positives = 74/173 (42%), Gaps = 25/173 (14%)
Query: 53 FVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAG--SDTARVRLE--------------- 95
F T+ +L ++ A D G YT ASNA G S TA + LE
Sbjct: 946 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWH 1005
Query: 96 ----VSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA 151
VS ++ P G+ P +F++ L L V G RF + + ++ W+ N++ +L
Sbjct: 1006 VSLSVSFKKEPLGQKP-SFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPT 1064
Query: 152 ERVSIVRDGS--FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKA 202
+ V + S G+++C A N G A+C+A L V PKA
Sbjct: 1065 KDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV-TPKA 1116
Score = 48.0 bits (109), Expect = 5e-05
Identities = 48/205 (23%), Positives = 75/205 (36%), Gaps = 15/205 (7%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
+S + + A V+++ AE ED P L D + G I ++ E V
Sbjct: 1944 SSESGTEEVATVKIQ-EAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE--VN 2000
Query: 141 WYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
WY + + E+ ++D ++ G + C A N G+ + SA L V+
Sbjct: 2001 WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 2060
Query: 200 PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD---------V 250
A +E L L C++ P +WFK REI D +
Sbjct: 2061 RAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 2118
Query: 251 FALTANAEDPTSLGTYTCEAVNCMG 275
+L G YTC+A N G
Sbjct: 2119 SSLEILRTQVVDCGEYTCKASNEYG 2143
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 1/113 (0%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
DT + E G PP FL+ L+ + G F ++ VTW++ ++
Sbjct: 1282 DTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ 1341
Query: 148 LLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
L + +I+ + G + C AEN+ G ++C+A L VL+
Sbjct: 1342 LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 1394
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWF---------KDSREIKAGDVFALTA 255
P F++E+ G V+ L V+G+P P ++WF D + + GD +L
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASR----EGSLKPNSSGLSPEPPPI 309
G YTC A N G+ S+ K++ G + E ++ + L PP
Sbjct: 1244 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 1303
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
F +EL+ P +V P P +V W+ KE K
Sbjct: 1304 FLKELKPIRCAQGLPAIFEYTVVGEPAP-TVTWF-KENK 1340
Score = 37.9 bits (84), Expect = 0.053
Identities = 49/193 (25%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL ++ + D G YT + + + S +L+V A + + L++LTV
Sbjct: 231 RLIIAATKLDDIGEYTYKVATSKTS----AKLKVEAVK---------IKKTLKNLTVTET 277
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
F VE+ V W +N L E+ +I G+ + +
Sbjct: 278 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL 337
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
GR SA L+V K K+P+ V L E TV+ E V PV +WF +
Sbjct: 338 ----GRLGASARLHVETVKIIKKPKDVTAL-----ENATVAFEVSVSHDTVPV-KWFHKN 387
Query: 243 REIKAGDVFALTA 255
EIK D L +
Sbjct: 388 VEIKPSDKHRLVS 400
Score = 30.7 bits (66), Expect = 8.1
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
N ED G Y CEA+N G+ +S+K+ VV RA+
Sbjct: 2031 NTEDHQ--GEYVCEALNDSGKTATSAKLTVVKRAA 2063
>AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform
protein.
Length = 1294
Score = 81.0 bits (191), Expect = 6e-15
Identities = 72/254 (28%), Positives = 110/254 (43%), Gaps = 32/254 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
R+ +S R D G YT AG + + V L V+A E PP L+ LQ +TV+ G
Sbjct: 760 RMFISETRQSDAGEYTF----VAGRNRSSVTLYVNAPE------PPQVLQELQPVTVQSG 809
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF I + K++WY+ E+ L + + DG + +TC A
Sbjct: 810 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 869
Query: 183 ENVGGRASCSAHLNVLVPKAYK--------RPEFVEELRALLTEQG-TVSLECKVVGVPT 233
+N G A+ SA L+V VP+ P + L+ +T +G +C+V G
Sbjct: 870 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 929
Query: 234 PVLRWFKDSREIKAGDVFALTANAED----------PTSLGTYTCEAVNCMGRAYSSSKV 283
V W+ ++IK F +T ED P GTYT A N +G+ S++ +
Sbjct: 930 KV-SWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 987
Query: 284 HV-VGRASREGSLK 296
+ V R+ S K
Sbjct: 988 SLEVQALDRQSSGK 1001
Score = 55.2 bits (127), Expect = 3e-07
Identities = 75/315 (23%), Positives = 123/315 (39%), Gaps = 41/315 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+ DR +E RL + + R D G YT+ AG + + +L V G D
Sbjct: 655 ITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV----VAGGNVSTAKLFV------EGRD-- 702
Query: 109 TFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRN--ERRLLEAERVSIVRDGSFFCX 165
+R ++ V+V + R +VE ++ + WY++ E ER V +
Sbjct: 703 VRIRSIKK-EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM 761
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G +T V GR S L V P+ P+ ++EL+ + + G +
Sbjct: 762 FISETRQSDAGEYTF----VAGRNRSSVTLYVNAPEP---PQVLQELQPVTVQSGKPARF 814
Query: 226 CKVV-GVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
C V+ G P P + W+K+ + + G + L P YTCEA N G
Sbjct: 815 CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 874
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPP 335
A +S+ + V + P+ P PP L+D +P C+ V
Sbjct: 875 VATTSASLSV----EVPEVVSPDQE--MPVYPPAIITPLQDTVTSEGQPARFQCR--VSG 926
Query: 336 WPRSVVWYNKEGKVE 350
V WY+K+ K++
Sbjct: 927 TDLKVSWYSKDKKIK 941
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/203 (26%), Positives = 84/203 (41%), Gaps = 27/203 (13%)
Query: 98 AEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
A+ES +GE P FL LQD+TVK G +FL + + VTW ++ E+ER+
Sbjct: 1083 AKES-TGEAPKIFLH-LQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQS 1140
Query: 158 RDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELR--- 213
++G+ G ++C N G + SA L+V P++ +E+
Sbjct: 1141 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEM 1200
Query: 214 --ALLTEQGTVSLE----------CKVVGVPTPVLRWFKDSREIKAGD---------VFA 252
A + ++ LE C++ P +WFK REI D + +
Sbjct: 1201 KAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 1260
Query: 253 LTANAEDPTSLGTYTCEAVNCMG 275
L G YTC+A N G
Sbjct: 1261 LEILRTQVVDCGEYTCKASNEYG 1283
Score = 52.0 bits (119), Expect = 3e-06
Identities = 45/176 (25%), Positives = 73/176 (41%), Gaps = 14/176 (7%)
Query: 36 AFILNTKSRAGASLDD-RFVSTEEAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVR 93
+FI T + GA +++ + + G ++ LT+ + D G+Y+ N G T
Sbjct: 1118 SFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAV 1177
Query: 94 LEVS-AEESPSGED-----------PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTW 141
L V A ES E P R+++ L V +G +F EI S+ + W
Sbjct: 1178 LSVEGAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 1237
Query: 142 YRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
++ R + E+++ SI G +TC A N G SC+A L V
Sbjct: 1238 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293
Score = 37.9 bits (84), Expect = 0.053
Identities = 49/193 (25%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL ++ + D G YT + + + S +L+V A + + L++LTV
Sbjct: 231 RLIIAATKLDDIGEYTYKVATSKTS----AKLKVEAVK---------IKKTLKNLTVTET 277
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
F VE+ V W +N L E+ +I G+ + +
Sbjct: 278 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL 337
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
GR SA L+V K K+P+ V L E TV+ E V PV +WF +
Sbjct: 338 ----GRLGASARLHVETVKIIKKPKDVTAL-----ENATVAFEVSVSHDTVPV-KWFHKN 387
Query: 243 REIKAGDVFALTA 255
EIK D L +
Sbjct: 388 VEIKPSDKHRLVS 400
Score = 34.7 bits (76), Expect = 0.50
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 53 FVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAG--SDTARVRLEVSA-EESPSGED 106
F T+ +L ++ A D G YT ASNA G S TA + LEV A + SG+D
Sbjct: 946 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKD 1002
>AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform
protein.
Length = 5604
Score = 80.6 bits (190), Expect = 8e-15
Identities = 68/240 (28%), Positives = 104/240 (43%), Gaps = 31/240 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
R+ +S R D G YT AG + + V L V+A E PP L+ LQ +TV+ G
Sbjct: 3204 RMFISETRQSDAGEYTF----VAGRNRSSVTLYVNAPE------PPQVLQELQPVTVQSG 3253
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF I + K++WY+ E+ L + + DG + +TC A
Sbjct: 3254 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3313
Query: 183 ENVGGRASCSAHLNVLVPKAYK--------RPEFVEELRALLTEQG-TVSLECKVVGVPT 233
+N G A+ SA L+V VP+ P + L+ +T +G +C+V G
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3373
Query: 234 PVLRWFKDSREIKAGDVFALTANAED----------PTSLGTYTCEAVNCMGRAYSSSKV 283
V W+ ++IK F +T ED P GTYT A N +G+ S++ +
Sbjct: 3374 KV-SWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3431
Score = 79.4 bits (187), Expect = 2e-14
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+PTPV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 55.2 bits (127), Expect = 3e-07
Identities = 75/315 (23%), Positives = 123/315 (39%), Gaps = 41/315 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+ DR +E RL + + R D G YT+ AG + + +L V G D
Sbjct: 3099 ITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV----VAGGNVSTAKLFVE------GRD-- 3146
Query: 109 TFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRN--ERRLLEAERVSIVRDGSFFCX 165
+R ++ V+V + R +VE ++ + WY++ E ER V +
Sbjct: 3147 VRIRSIKK-EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM 3205
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G +T A GR S L V P+ P+ ++EL+ + + G +
Sbjct: 3206 FISETRQSDAGEYTFVA----GRNRSSVTLYVNAPEP---PQVLQELQPVTVQSGKPARF 3258
Query: 226 CKVV-GVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMG 275
C V+ G P P + W+K+ + + G + L P YTCEA N G
Sbjct: 3259 CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 3318
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPP 335
A +S+ + V + P+ P PP L+D +P C+ V
Sbjct: 3319 VATTSASLSV----EVPEVVSPDQE--MPVYPPAIITPLQDTVTSEGQPARFQCR--VSG 3370
Query: 336 WPRSVVWYNKEGKVE 350
V WY+K+ K++
Sbjct: 3371 TDLKVSWYSKDKKIK 3385
Score = 54.4 bits (125), Expect = 6e-07
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 93 RLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE-- 150
RLE + E P F+ + G RF ++++ + W+ + ++++
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 151 AERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVE 210
+V I DG+ G WT A+N GR+S S L V + +P FVE
Sbjct: 1502 THKVVIKEDGTQ-SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 211 ELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
+L+ + ++G+ + ++ + G P P + W K+S
Sbjct: 1561 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNS 1593
Score = 54.4 bits (125), Expect = 6e-07
Identities = 80/341 (23%), Positives = 129/341 (37%), Gaps = 45/341 (13%)
Query: 51 DRFVSTEEAGGV-RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP- 108
D + E G V L +S + G+ G Y A N G + +++ +E PP
Sbjct: 5226 DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 5285
Query: 109 -TFLRRLQ-DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER-VSIVRDGSFFCX 165
T ++ DL +RT EI+ E +E+ + E E+ V IV F
Sbjct: 5286 VTHQHVMEFDLEHTTSSRTPSPQEIVLEVEL------SEKDVKEFEKQVKIVTVPEFTPD 5339
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSL 224
+ N+ R L + + P F+ + + E
Sbjct: 5340 HKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVF 5399
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAVNCM 274
+C V+G+PTP ++W+K+ I+ ++ + + + +L TY C AVNC+
Sbjct: 5400 KCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCV 5459
Query: 275 GRAY--------SSSKVHVVGRASR--------EGSLKPNSSG-----LSPEPPPIFTRE 313
G A S V+ + S+ E LK N + E PP F +
Sbjct: 5460 GEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKG 5519
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ D Y I C + P P +V WY K+GK+ G R
Sbjct: 5520 ISDCYAPIGTAAYFQCLVRGSPRP-TVYWY-KDGKLVQGRR 5558
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
E SPS E P F R+Q TV G+ F V ++ + + WY+N ++ ++R+
Sbjct: 2070 ELSPSMEAPKIF-ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYW 2128
Query: 159 DGSFFC-XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT 217
C A N+ G S A L V +A + F +EL+ ++
Sbjct: 2129 PEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV---QAKQLITFTQELQDVVA 2185
Query: 218 -EQGTV-SLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
E+ T+ + EC+ P ++W+KD E+ GD + +
Sbjct: 2186 KEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYRM 2222
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V +E G L + A D+G +T+ A N AG + V L V A E + P F+ +
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH---QVKPMFVEK 1561
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF-CXXXXXXXX 172
L+++ +K G++ V + + W +N ++ + I +G+
Sbjct: 1562 LKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTV 1621
Query: 173 XXXGRW-TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
W T TA N GR + +NV V A PE R L+ +GT
Sbjct: 1622 SQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE-----RKLIIPRGT 1666
Score = 48.0 bits (109), Expect = 5e-05
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 7/152 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V ++ GV +T +T R + L A ++TARV V E P PPT +
Sbjct: 896 VEVKKEVGVSITGTTVR--EERFEVLHGREAKVTETARVPAPV---EIPV--TPPTLVSG 948
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+++TV G I VTWYR + ++ + I
Sbjct: 949 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 1008
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKR 205
GR+TC+A N G S S +L V V + +++
Sbjct: 1009 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 1040
Score = 48.0 bits (109), Expect = 5e-05
Identities = 29/101 (28%), Positives = 44/101 (43%)
Query: 98 AEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
A E E PP+F+ L V T F+VE+ V WYRN+ L ER+ +
Sbjct: 5173 AIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKME 5232
Query: 158 RDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
R G+ G + C A N+ G A A+++++
Sbjct: 5233 RVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 41.5 bits (93), Expect = 0.004
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAV 271
V+ CK+ G P P + W+KD + IK G+ + + + SL G YT A
Sbjct: 1308 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1367
Query: 272 NCMGRAYSSSKVHV 285
N G A S K++V
Sbjct: 1368 NIKGNAICSGKLYV 1381
Score = 41.1 bits (92), Expect = 0.006
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 10/102 (9%)
Query: 206 PEFVEEL-RALLTEQGTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P F+E L + + E T+ +V G+P P ++W+++ + + G+V +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEI 5242
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKP 297
+ G Y C AVN +G A S + V ++ + R +L P
Sbjct: 5243 SNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPP 5284
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS-FF 163
E PP F++ + D +GT F + S V WY+ + +L++ R ++ G+ F
Sbjct: 5511 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYK-DGKLVQGRRFTVEESGTGFH 5569
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G + C A N G A A L +
Sbjct: 5570 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 38.7 bits (86), Expect = 0.031
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALT---------- 254
P V L+ + +G +V+LEC + G P+P + W+++ +I++ F +T
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 255 --ANAEDPTSLGTYTCEAVNCMGRAYSS 280
A AED G +TC AVN G +S
Sbjct: 1003 REAFAEDS---GRFTCSAVNEAGTVSTS 1027
Score = 37.9 bits (84), Expect = 0.053
Identities = 49/193 (25%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL ++ + D G YT + + + S +L+V A + + L++LTV
Sbjct: 2675 RLIIAATKLDDIGEYTYKVATSKTS----AKLKVEAVK---------IKKTLKNLTVTET 2721
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
F VE+ V W +N L E+ +I G+ + +
Sbjct: 2722 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL 2781
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
GR SA L+V K K+P+ V L E TV+ E V PV +WF +
Sbjct: 2782 ----GRLGASARLHVETVKIIKKPKDVTAL-----ENATVAFEVSVSHDTVPV-KWFHKN 2831
Query: 243 REIKAGDVFALTA 255
EIK D L +
Sbjct: 2832 VEIKPSDKHRLVS 2844
Score = 35.5 bits (78), Expect = 0.28
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 14/108 (12%)
Query: 203 YKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAG---------DVFA 252
Y +P F ++L +G V C+++ PTP + WF ++R I G D+
Sbjct: 3501 YFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHH 3560
Query: 253 LTANAE----DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLK 296
+++ E G+Y A+N G A S++ + V+ + E L+
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLE 3608
Score = 33.9 bits (74), Expect = 0.87
Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 11/100 (11%)
Query: 206 PEFVEEL--RALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALT 254
P+ ++E+ A E ++ LEC + G P PV+ WF++ +K F L
Sbjct: 4158 PKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLY 4217
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ G Y C A N G S S + V RE S
Sbjct: 4218 IKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENS 4257
Score = 32.7 bits (71), Expect = 2.0
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 277 AYSSSK-VHVVGRASREGSLKPNSSGLSPEP-PPIFTRELEDQYVRICEPFTLSCQIVVP 334
A+S S+ + A++ + + +S+ PE P FT++L +YV EP +C+++
Sbjct: 3471 AFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIAC 3530
Query: 335 PWPRSVVWYNKEGKVEAGER 354
P P + W++ + G R
Sbjct: 3531 PTP-EMTWFHNNRPIPTGLR 3549
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
Score = 31.9 bits (69), Expect = 3.5
Identities = 26/111 (23%), Positives = 41/111 (36%), Gaps = 5/111 (4%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP+FL+ ++ V G F+ + VTWY N+ + + I ++
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILT 4002
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-----KAYKRPEFVEEL 212
G TC N G ++ L V KA+K P F + L
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYL 4053
Score = 31.1 bits (67), Expect = 6.1
Identities = 17/49 (34%), Positives = 24/49 (48%)
Query: 53 FVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
F T+ +L ++ A D G YT ASNA G ++ L + A ES
Sbjct: 3390 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3438
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 80.6 bits (190), Expect = 8e-15
Identities = 68/240 (28%), Positives = 104/240 (43%), Gaps = 31/240 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
R+ +S R D G YT AG + + V L V+A E PP L+ LQ +TV+ G
Sbjct: 3158 RMFISETRQSDAGEYTF----VAGRNRSSVTLYVNAPE------PPQVLQELQPVTVQSG 3207
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF I + K++WY+ E+ L + + DG + +TC A
Sbjct: 3208 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3267
Query: 183 ENVGGRASCSAHLNVLVPKAYK--------RPEFVEELRALLTEQG-TVSLECKVVGVPT 233
+N G A+ SA L+V VP+ P + L+ +T +G +C+V G
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3327
Query: 234 PVLRWFKDSREIKAGDVFALTANAED----------PTSLGTYTCEAVNCMGRAYSSSKV 283
V W+ ++IK F +T ED P GTYT A N +G+ S++ +
Sbjct: 3328 KV-SWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 79.4 bits (187), Expect = 2e-14
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+PTPV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 9/196 (4%)
Query: 15 VRRSATLDIHPQYDRWRHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDT 74
VR T+ +HP+ HV + K + G + D ++ + G +LT+++ T D
Sbjct: 25210 VRFGVTITVHPE-----PHVTWYKSGQKIKPGDN-DKKYTFESDKGLYQLTINSVTTDDD 25263
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIIS 133
YT+ A N G D+ + +L V+ P+ P F R L + + G F + +
Sbjct: 25264 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 25323
Query: 134 STECKVTWYRNERRLLEAERVSIVRDG-SFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
+ W ++ + L + I+ +G ++ G + TA N G SC
Sbjct: 25324 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQ 25383
Query: 193 AHLNVLVPKAYKRPEF 208
AHL V YK+ EF
Sbjct: 25384 AHLQV-ERLRYKKQEF 25398
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 63.7 bits (148), Expect = 9e-10
Identities = 53/199 (26%), Positives = 77/199 (38%), Gaps = 18/199 (9%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGS 161
E PP F L + T VG RF V I E VTWY++ +++ + + + D
Sbjct: 25190 ERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG 25249
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV----PKAYKRPEFVEELRALLT 217
+ +T A N G SC A L V + + RP F L
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAEC 25309
Query: 218 EQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALTANAEDPTSLGTY 266
++G +V E +V G+P P L+W KD + + G D +AL P G Y
Sbjct: 25310 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25369
Query: 267 TCEAVNCMGRAYSSSKVHV 285
A N G + + V
Sbjct: 25370 RVTATNTAGSTSCQAHLQV 25388
Score = 62.1 bits (144), Expect = 3e-09
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P F++ + + + +G V +I + K+ W+ N L + V DG
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNV--------------LVPKAYKR------PE 207
G +TC A N G+ CSA+L + V K+ ++ P
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 208 FVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKDSREIKAGDVFALTAN--------AE 258
F++EL+ + QG ++ E VVG P P + WFK+++++ + + N
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636
Query: 259 DP--TSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
DP G Y C+A N +G + ++++ V+ + + P + +PE P F
Sbjct: 3637 DPQREDSGLYICKAENMLGESTCAAELLVL-LEDTDMTDTPCKAKSTPEAPEDF 3689
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 7/157 (4%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGD-TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
D++F ++ L + T D G Y +A N +G +L V +P
Sbjct: 4284 DEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP------ 4337
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
R+++ L V +G +F EI S+ + W++ R + E+++ SI
Sbjct: 4338 VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEIL 4397
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKR 205
G +TC A N G SC+A L V VP K+
Sbjct: 4398 RTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4434
Score = 56.4 bits (130), Expect = 1e-07
Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 15/178 (8%)
Query: 76 VYTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEI 131
V+TL + D V+L ++ + E P F + L+D TV+ G T L
Sbjct: 5752 VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGA-TAVLECE 5810
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+S KV W++N +L++++ IV DG +TC A++ + SC
Sbjct: 5811 VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSC 5868
Query: 192 SAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG 248
+LNV+ P EF+ L L + E+ EC++ V +WFKD EIK G
Sbjct: 5869 --NLNVVPPHV----EFLRPLTDLQVREKEMARFECELSRENAKV-KWFKDGAEIKKG 5919
Score = 55.2 bits (127), Expect = 3e-07
Identities = 75/315 (23%), Positives = 123/315 (39%), Gaps = 41/315 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+ DR +E RL + + R D G YT+ AG + + +L V G D
Sbjct: 3053 ITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV----VAGGNVSTAKLFVE------GRD-- 3100
Query: 109 TFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRN--ERRLLEAERVSIVRDGSFFCX 165
+R ++ V+V + R +VE ++ + WY++ E ER V +
Sbjct: 3101 VRIRSIKK-EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM 3159
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G +T A GR S L V P+ P+ ++EL+ + + G +
Sbjct: 3160 FISETRQSDAGEYTFVA----GRNRSSVTLYVNAPEP---PQVLQELQPVTVQSGKPARF 3212
Query: 226 CKVV-GVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMG 275
C V+ G P P + W+K+ + + G + L P YTCEA N G
Sbjct: 3213 CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 3272
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPP 335
A +S+ + V + P+ P PP L+D +P C+ V
Sbjct: 3273 VATTSASLSV----EVPEVVSPDQE--MPVYPPAIITPLQDTVTSEGQPARFQCR--VSG 3324
Query: 336 WPRSVVWYNKEGKVE 350
V WY+K+ K++
Sbjct: 3325 TDLKVSWYSKDKKIK 3339
Score = 54.4 bits (125), Expect = 6e-07
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 93 RLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE-- 150
RLE + E P F+ + G RF ++++ + W+ + ++++
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455
Query: 151 AERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVE 210
+V I DG+ G WT A+N GR+S S L V + +P FVE
Sbjct: 1456 THKVVIKEDGTQ-SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514
Query: 211 ELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
+L+ + ++G+ + ++ + G P P + W K+S
Sbjct: 1515 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNS 1547
Score = 53.6 bits (123), Expect = 1e-06
Identities = 39/183 (21%), Positives = 72/183 (39%), Gaps = 3/183 (1%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
A N G R R +S + + + P + ++D+T K+G + +I+ +
Sbjct: 24010 AENETGLSRPR-RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK 24068
Query: 141 WYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
WYR + L+++ + + DG G +TC A N G S+ L +L
Sbjct: 24069 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQA 24127
Query: 201 KAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDP 260
P + + + T+ L +G P P + WF + ++ + + N E
Sbjct: 24128 TPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITI-ENTEHY 24186
Query: 261 TSL 263
T L
Sbjct: 24187 THL 24189
Score = 51.2 bits (117), Expect = 5e-06
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+ A D G+ T + G + L +S E S D P F+ + + + G
Sbjct: 26597 LTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS----DAPAFISQPRSQNINEGQ 26652
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F EI ++ W++N + + VSI R + + G++T A+
Sbjct: 26653 NVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAK 26712
Query: 184 NVGGRASCSAHLNVL 198
N G+ S +A L VL
Sbjct: 26713 NFRGQCSATASLMVL 26727
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
E SPS E P F R+Q TV G+ F V ++ + + WY+N ++ ++R+
Sbjct: 2024 ELSPSMEAPKIF-ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYW 2082
Query: 159 DGSFFC-XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT 217
C A N+ G S A L V +A + F +EL+ ++
Sbjct: 2083 PEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV---QAKQLITFTQELQDVVA 2139
Query: 218 -EQGTV-SLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
E+ T+ + EC+ P ++W+KD E+ GD + +
Sbjct: 2140 KEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYRM 2176
Score = 50.4 bits (115), Expect = 9e-06
Identities = 62/242 (25%), Positives = 92/242 (38%), Gaps = 32/242 (13%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA 98
N K + A L +E G + L + R TG QA+N S RV+ V
Sbjct: 5641 NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIG 5700
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
LR L+D+TV G F E+ S + V WY ++L +++V
Sbjct: 5701 -----------LLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKVVPRS 5748
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTE 218
+G G TA++ H N+ V + EF + L E
Sbjct: 5749 EGKVHTLTLRDVKLEDAGEVQLTAKDF------KTHANLFVKEP--PVEFTKPLEDQTVE 5800
Query: 219 QG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE---------DPTSLGTYTC 268
+G T LEC+V V +WFK+ EI + + A+ P + TYTC
Sbjct: 5801 EGATAVLECEVSRENAKV-KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5859
Query: 269 EA 270
+A
Sbjct: 5860 DA 5861
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
Query: 183 ENVGGRASCSAHLNVLVPKA---YKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRW 238
EN+GG + S + PK+ + P F EELR L + Q +L CKV G P P+++W
Sbjct: 24405 ENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKW 24464
Query: 239 FKDSREIKA 247
++ +EI A
Sbjct: 24465 YRQGKEIIA 24473
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V +E G L + A D+G +T+ A N AG + V L V A E + P F+ +
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH---QVKPMFVEK 1515
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF-CXXXXXXXX 172
L+++ +K G++ V + + W +N ++ + I +G+
Sbjct: 1516 LKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTV 1575
Query: 173 XXXGRW-TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
W T TA N GR + +NV V A PE R L+ +GT
Sbjct: 1576 SQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE-----RKLIIPRGT 1620
Score = 49.2 bits (112), Expect = 2e-05
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 6/152 (3%)
Query: 51 DRFVST-EEAGGVRLTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPP 108
D++V+ E ++ V+ G Y ++A N G S +R E+ A ++ E P
Sbjct: 7135 DKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQ--EAPE 7192
Query: 109 TFL--RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
FL + L LTVK GT+ + E K+TW + + L + +R++I
Sbjct: 7193 IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVT 7252
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
G + A NV GRA+ +NVL
Sbjct: 7253 IVDSKRSDTGTYIIEAVNVCGRATAVVEVNVL 7284
Score = 48.4 bits (110), Expect = 4e-05
Identities = 56/238 (23%), Positives = 86/238 (36%), Gaps = 20/238 (8%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
+S + + A V+++ AE ED P L D + G I ++ E V
Sbjct: 4217 SSESGTEEVATVKIQ-EAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE--VN 4273
Query: 141 WYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
WY + + E+ ++D ++ G + C A N G+ + SA L V+
Sbjct: 4274 WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 4333
Query: 200 PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD---------V 250
A +E L L C++ P +WFK REI D +
Sbjct: 4334 RAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4391
Query: 251 FALTANAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASREGSLKPNSSGLSPEP 306
+L G YTC+A N G ++ V V G + L P PEP
Sbjct: 4392 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER---KPEP 4446
Score = 48.0 bits (109), Expect = 5e-05
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 7/152 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V ++ GV +T +T R + L A ++TARV V E P PPT +
Sbjct: 850 VEVKKEVGVSITGTTVR--EERFEVLHGREAKVTETARVPAPV---EIPV--TPPTLVSG 902
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+++TV G I VTWYR + ++ + I
Sbjct: 903 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 962
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKR 205
GR+TC+A N G S S +L V V + +++
Sbjct: 963 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 994
Score = 47.6 bits (108), Expect = 7e-05
Identities = 46/170 (27%), Positives = 72/170 (42%), Gaps = 20/170 (11%)
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXX 169
FL L+D+T K F VE+ S +V W++N++RL VS+ +G
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVEL-SHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKD 5492
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL-TEQGTVSLECKV 228
+ E +G S A L VL Y F +L+ E+ V L+C++
Sbjct: 5493 LSIDDTSQ--IRVEAMG--MSSEAKLTVLEGDPY----FTGKLQDYTGVEKDEVILQCEI 5544
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAED---------PTSLGTYTCE 269
PV +WFKD +EIK + A+ + + +G YTC+
Sbjct: 5545 SKADAPV-KWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5593
Score = 47.2 bits (107), Expect = 9e-05
Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 9/193 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP---PTF 110
V+TEE +V G + ++ N G E+S +P + P P F
Sbjct: 24377 VTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWS---EISEPITPKSDVPIQAPHF 24433
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD--GSFFCXXXX 168
L++L V+ + + ++ + V WYR + ++ +++ G +
Sbjct: 24434 KEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIA 24493
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECK 227
+ A N GG S +A L V VP P+ +E + A+ +G VS++
Sbjct: 24494 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIP 24553
Query: 228 VVGVPTPVLRWFK 240
G P PV+ W K
Sbjct: 24554 FSGKPDPVITWQK 24566
Score = 46.4 bits (105), Expect = 2e-04
Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 13/180 (7%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+++ G R I +T+ K W N L +E GS G
Sbjct: 26551 MSINEGQRLVLKANIAGATDVK--WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26608
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV 235
TC ++ G C L L + P F+ + R+ +G V C++ G P+P
Sbjct: 26609 ILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667
Query: 236 LRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ WFK++ I ++ +V++L + G YT +A N G+ +++ + V+
Sbjct: 26668 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 45.2 bits (102), Expect = 4e-04
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 10/88 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P +E++ + T+ G + L C++VG P P ++W++ +E+ G LT
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
E+ G YTC A N +G +SSK+
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKL 24123
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 1/113 (0%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
DT + E G PP FL+ L+ + G F ++ VTW++ ++
Sbjct: 3555 DTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ 3614
Query: 148 LLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
L + +I+ + G + C AEN+ G ++C+A L VL+
Sbjct: 3615 LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3667
Score = 42.3 bits (95), Expect = 0.002
Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 21/193 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ ++ D GVYT + G T+ RL V+ F+ L+D TVK G
Sbjct: 5044 LVINDSQFDDEGVYTAEVE---GKKTS-ARLFVTGIRLK-------FMSPLEDQTVKEGE 5092
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F+ E+ S + V W++N+ +L + V I +G + +
Sbjct: 5093 TATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK 5151
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
+ S +A L VL Y + ++ E+ ++L+C+V PV +WFKD
Sbjct: 5152 EL----SSTAQLKVLEADPYFTVKLHDKTAV---EKDEITLKCEV-SKDVPV-KWFKDGE 5202
Query: 244 EIKAGDVFALTAN 256
EI +++ A+
Sbjct: 5203 EIVPSPKYSIKAD 5215
Score = 41.5 bits (93), Expect = 0.004
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAV 271
V+ CK+ G P P + W+KD + IK G+ + + + SL G YT A
Sbjct: 1262 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1321
Query: 272 NCMGRAYSSSKVHV 285
N G A S K++V
Sbjct: 1322 NIKGNAICSGKLYV 1335
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 15/127 (11%)
Query: 196 NVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-- 252
NV+ +P E ++ +G +S+ VP P + W KD +E+KA D
Sbjct: 7880 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 7939
Query: 253 ---LTANAEDPTSL----GTYTCEAVNCMGRAYSSSKVHVVG-----RASREGSLKPNSS 300
++A+ E P S+ G YT N +G A +S V V+G + + + +S
Sbjct: 7940 NDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSC 7999
Query: 301 GLSPEPP 307
L+ EPP
Sbjct: 8000 KLTWEPP 8006
Score = 41.5 bits (93), Expect = 0.004
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+TV+VG R L + E +TW + + L+ +RV +++D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 177 RWTCTAENVGGRASCSAHLNVL 198
++ +A+N G A SA +NVL
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVL 11502
Score = 41.5 bits (93), Expect = 0.004
Identities = 26/120 (21%), Positives = 43/120 (35%), Gaps = 4/120 (3%)
Query: 82 SNAAGSDTARVRLEVSAEESPSGEDP----PTFLRRLQDLTVKVGTRTRFLVEIISSTEC 137
S SD V+ + P +P P + LQD TV + +F V+
Sbjct: 26325 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 26384
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
W ++ + + + + + D F G +TCT +N G S S L +
Sbjct: 26385 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Score = 41.1 bits (92), Expect = 0.006
Identities = 25/109 (22%), Positives = 43/109 (39%)
Query: 89 TARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL 148
T+ + EV +++ + + P R++ V G TRF++ + S +V WY N L
Sbjct: 25858 TSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL 25917
Query: 149 LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
E+ ++ G + N G AS A L+V
Sbjct: 25918 QESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWF---------KDSREIKAGDVFALTA 255
P F++E+ G V+ L V+G+P P ++WF D + + GD +L
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASR----EGSLKPNSSGLSPEPPPI 309
G YTC A N G+ S+ K++ G + E ++ + L PP
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
F +EL+ P +V P P +V W+ KE K
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAP-TVTWF-KENK 3613
Score = 39.1 bits (87), Expect = 0.023
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
TK + ++ +E+ GG L + T D+G+YT N+AGS ++ +L + A +
Sbjct: 26389 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26448
Query: 101 SPSGEDPPTFLRRLQDLT--VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
+ T ++ ++T K + + + S E K++ +++ +L E S V
Sbjct: 26449 DTEAQKVST--QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 26505
Score = 38.7 bits (86), Expect = 0.031
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALT---------- 254
P V L+ + +G +V+LEC + G P+P + W+++ +I++ F +T
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 255 --ANAEDPTSLGTYTCEAVNCMGRAYSS 280
A AED G +TC AVN G +S
Sbjct: 957 REAFAEDS---GRFTCSAVNEAGTVSTS 981
Score = 38.7 bits (86), Expect = 0.031
Identities = 31/138 (22%), Positives = 55/138 (39%), Gaps = 5/138 (3%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLE-VSAEESPSGEDPPTFLRRLQD-LTVK 120
+ TV + GDT Y + A N G + ++ ++ + PPT +D LT++
Sbjct: 10278 KYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA---PPTLHLDFRDKLTIR 10334
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
VG + KV+W+++E +LE +R I + G++
Sbjct: 10335 VGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCV 10394
Query: 181 TAENVGGRASCSAHLNVL 198
EN G +NV+
Sbjct: 10395 VVENSTGSRKGFCQVNVV 10412
Score = 38.3 bits (85), Expect = 0.040
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 17/124 (13%)
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFK 240
A N G + SA + + P ++ + E+GT V++ K+ GVP P L WFK
Sbjct: 9596 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9655
Query: 241 ------DSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVH 284
D++E + D L + G YT AVN +G A +++
Sbjct: 9656 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9715
Query: 285 VVGR 288
V+GR
Sbjct: 9716 VLGR 9719
Score = 38.3 bits (85), Expect = 0.040
Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 3/137 (2%)
Query: 65 TVSTARTGDTGVYTLQASNAAG--SDTARVRLEVSAEESPSGEDPPTFLRRLQDL-TVKV 121
TV+ GDT + + A NAAG S + V+ + + R DL T++
Sbjct: 22505 TVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRA 22564
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
G+ + E K+ W + ++ L E+VS+ G G++T T
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 22624
Query: 182 AENVGGRASCSAHLNVL 198
+N G + S + VL
Sbjct: 22625 VKNASGTKAVSVMVKVL 22641
Score = 37.9 bits (84), Expect = 0.053
Identities = 49/193 (25%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL ++ + D G YT + + + S +L+V A + + L++LTV
Sbjct: 2629 RLIIAATKLDDIGEYTYKVATSKTS----AKLKVEAVK---------IKKTLKNLTVTET 2675
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
F VE+ V W +N L E+ +I G+ + +
Sbjct: 2676 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL 2735
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
GR SA L+V K K+P+ V L E TV+ E V PV +WF +
Sbjct: 2736 ----GRLGASARLHVETVKIIKKPKDVTAL-----ENATVAFEVSVSHDTVPV-KWFHKN 2785
Query: 243 REIKAGDVFALTA 255
EIK D L +
Sbjct: 2786 VEIKPSDKHRLVS 2798
Score = 37.5 bits (83), Expect = 0.071
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 16/143 (11%)
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGT-VSLECKVVGVPTPVLRW 238
TA N+ + S + +L R + +++LLT + GT V L+ V G P P + W
Sbjct: 12773 TAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSW 12832
Query: 239 FKDSREIK--AGDVFALTAN-------AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA 289
KD +K G A+ N + + G YT A N G ++ K+ V+ +
Sbjct: 12833 KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 12892
Query: 290 SREGSLKPNS-----SGLSPEPP 307
S+K N + LS EPP
Sbjct: 12893 GPPASVKINKMYSDRAMLSWEPP 12915
Score = 37.5 bits (83), Expect = 0.071
Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 6/146 (4%)
Query: 58 EAGGVR-LTVSTARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRL 114
EAG + LT + R + Y ++A N AG R + P E P L +
Sbjct: 22097 EAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIE-PTADLTGI 22155
Query: 115 --QDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
Q +T K G+ V I KVTW E RL E +RVSI
Sbjct: 22156 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMR 22215
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVL 198
GR+ T EN G + S + V+
Sbjct: 22216 GDSGRYFLTLENTAGVKTFSVTVVVI 22241
Score = 36.7 bits (81), Expect = 0.12
Identities = 40/158 (25%), Positives = 59/158 (37%), Gaps = 3/158 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
E + V+ R G T + + A NAAG SD A V V ++ + +
Sbjct: 10670 ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAR 10729
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+ +KVG R I KVTW + +R R+ + GS
Sbjct: 10730 EQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKL--EIRNAAHEDG 10787
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR 213
G ++ T EN G + S + VL R V E+R
Sbjct: 10788 GIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIR 10825
Score = 35.9 bits (79), Expect = 0.22
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
E P F+ L+D TV F ++ S + V WYRN R + E ++ +DGS
Sbjct: 6323 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYKFEKDGS 6378
Score = 35.9 bits (79), Expect = 0.22
Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 9/82 (10%)
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAV 271
+V L + G P P + W+KD +E++ D+ ++ D + G Y +
Sbjct: 20392 SVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLR 20451
Query: 272 NCMGRAYSSSKVHVVGRASREG 293
N MG A ++ +V ++ + G
Sbjct: 20452 NAMGSASATIRVQILDKPGPPG 20473
Score = 35.9 bits (79), Expect = 0.22
Identities = 42/202 (20%), Positives = 79/202 (39%), Gaps = 12/202 (5%)
Query: 50 DDRFVSTEEAGGVRLT---VSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGE 105
++ + + G VR T VS + G + + A N AG + + V A++
Sbjct: 20713 EEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP 20772
Query: 106 DPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
+ + + K G + L+ VTW ++E+ L R SI S
Sbjct: 20773 EIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLL 20832
Query: 166 XXXXXXXXXXGRWTCTAEN-VGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G++ T EN VG S + + VL P ++L+ +GTV+L
Sbjct: 20833 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVL-----DTPAACQKLQVKHVSRGTVTL 20887
Query: 225 --ECKVVGVPTPVLRWFKDSRE 244
+ ++ +P++ + + R+
Sbjct: 20888 LWDPPLIDGGSPIINYVIEKRD 20909
Score = 35.5 bits (78), Expect = 0.28
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 21/242 (8%)
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+D VK F E+ ++ K W+RNE + ++ + I++ +
Sbjct: 6149 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGTVSLECKVVGVP 232
+ + N G SA N++V + R VE L+ + T E+ +V+ CKV +
Sbjct: 6208 DQANYNVSLTNHRGENVKSA-ANLIVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL- 6263
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
L+W K+ E+ + + + + +C + ++V
Sbjct: 6264 NVTLKWTKNGEEVPFDNRVSYRVDKY------KHMLTIKDC---GFPDEGEYIV----TA 6310
Query: 293 GSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAG 352
G K + L E P F LEDQ V + SCQ+ +V WY +++ G
Sbjct: 6311 GQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQL--SREKANVKWYRNGREIKEG 6368
Query: 353 ER 354
++
Sbjct: 6369 KK 6370
Score = 35.5 bits (78), Expect = 0.28
Identities = 37/199 (18%), Positives = 72/199 (36%), Gaps = 5/199 (2%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
V+ + G T + ++A N G + + +E ++ ++ L VK GT
Sbjct: 10972 VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTV 11031
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
RF I W + + E ++ D G + T N
Sbjct: 11032 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA 11091
Query: 186 GGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSRE 244
G + + HL VL VP P + + + E T+S + +PV+ + + ++
Sbjct: 11092 AGSKTVAVHLTVLDVPGPPTGPINILD---VTPEHMTISWQPPKDDGGSPVINYIVEKQD 11148
Query: 245 IKAGDVFALTANAEDPTSL 263
+ D + + ++ T L
Sbjct: 11149 TRK-DTWGVVSSGSSKTKL 11166
Score = 35.5 bits (78), Expect = 0.28
Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 5/149 (3%)
Query: 96 VSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVS 155
+ AE P D ++ L LTVK GT + V+W ++ L AE +
Sbjct: 12789 ILAENVPPRIDLSVAMKSL--LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK 12846
Query: 156 IVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL 215
+ + G +T TAEN G S + L VL P ++ +
Sbjct: 12847 MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG---PPASVKINKM 12903
Query: 216 LTEQGTVSLECKVVGVPTPVLRWFKDSRE 244
+++ +S E + + + + D RE
Sbjct: 12904 YSDRAMLSWEPPLEDGGSEITNYIVDKRE 12932
Score = 35.1 bits (77), Expect = 0.38
Identities = 29/128 (22%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 205 RPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANA------ 257
+P V L+ +V+ K G P P W KD + I G + L+ +
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 258 ---EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS--LKPNSSGLSPEPPPIFTR 312
D + G YTC N G SS K+ + E +S ++P+ +
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 26473
Query: 313 ELEDQYVR 320
E+ + +R
Sbjct: 26474 EISQKALR 26481
Score = 34.3 bits (75), Expect = 0.66
Identities = 48/210 (22%), Positives = 80/210 (38%), Gaps = 13/210 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV T D GVYT A+N G +L + A +P P L+ + VG+
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA--TPQFH-PGYPLK--EKYYGAVGS 24147
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF-FCXXXXXXXXXXXGRWTCTA 182
R V I +TW+ ++ L +E ++I + G++
Sbjct: 24148 TLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 24207
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
NV G + A L+V + +P + ALL +S + + + + +
Sbjct: 24208 SNVFG--TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 24265
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVN 272
E K G + L ++A + TC VN
Sbjct: 24266 CEAKEGAEWQLVSSA-----ISVTTCRIVN 24290
Score = 33.9 bits (74), Expect = 0.87
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 206 PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREI------KAGDVFALTA-NAE 258
PE+ + L ++ ++ ++ V G P P + WFKD EI + DV T+
Sbjct: 21465 PEYFDGL--IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVR 21522
Query: 259 DPT--SLGTYTCEAVNCMGRAYSSSKVHV 285
D T G YT EA N G A + KV V
Sbjct: 21523 DATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 33.9 bits (74), Expect = 0.87
Identities = 16/41 (39%), Positives = 24/41 (58%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
T+ G L V A GVYT++A NA+GS A ++++V
Sbjct: 21511 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 33.5 bits (73), Expect = 1.1
Identities = 39/182 (21%), Positives = 70/182 (38%), Gaps = 21/182 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G Y + ++ +V E++AE F+ + Q+L + G
Sbjct: 6022 LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAE----------FISKPQNLEILEGE 6070
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ F+ I S V W R+++ L ++ ++ DG G +
Sbjct: 6071 KAEFVCSI-SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV- 6128
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G A +AHL V+ P +++ R + EQ V C+ V +WF++
Sbjct: 6129 ---GAARAAAHLTVIEKLRIVVP--LKDTR--VKEQQEVVFNCE-VNTEGAKAKWFRNEE 6180
Query: 244 EI 245
I
Sbjct: 6181 AI 6182
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/43 (44%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
V T+ V LT+ DTG Y + SNAAGS T V L V
Sbjct: 11062 VETDNFSSV-LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 33.1 bits (72), Expect = 1.5
Identities = 29/139 (20%), Positives = 53/139 (38%), Gaps = 4/139 (2%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ G+ V G+ + + A N+AG R V +E P
Sbjct: 14512 DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTML--PELD 14569
Query: 111 LRRL-QDLTV-KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
LR + Q L + K G + + ++ + VTW + ++ L + +RV+ +
Sbjct: 14570 LRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNIN 14629
Query: 169 XXXXXXXGRWTCTAENVGG 187
G + TA N+ G
Sbjct: 14630 ECVRSDSGPYPLTARNIVG 14648
Score = 32.7 bits (71), Expect = 2.0
Identities = 32/158 (20%), Positives = 57/158 (36%), Gaps = 3/158 (1%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
DR+ + L V+ + G + + A NA G R V E+ PP
Sbjct: 12348 DRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVY--EAKEQLLPPKI 12405
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
L Q +T+K G + R + W + E ++ + +++ + S
Sbjct: 12406 LMPEQ-ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDV 12464
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEF 208
G ++ TAEN G + + V+ +P F
Sbjct: 12465 TRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502
Score = 32.7 bits (71), Expect = 2.0
Identities = 32/127 (25%), Positives = 47/127 (37%), Gaps = 10/127 (7%)
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPTPVLR 237
C A G A + V Y E E + + + G + L + G P P+ +
Sbjct: 23613 CNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICK 23672
Query: 238 WFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA- 289
W K+ ++I + A L D GTY N G+ KV V+G
Sbjct: 23673 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPN 23732
Query: 290 SREGSLK 296
S EG L+
Sbjct: 23733 SPEGPLE 23739
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 10/90 (11%)
Query: 209 VEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANAEDP 260
V+ L L + GT + L V G P P + W K +K + T D
Sbjct: 7197 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS 7256
Query: 261 --TSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
+ GTY EAVN GRA + +V+V+ +
Sbjct: 7257 KRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286
Score = 31.9 bits (69), Expect = 3.5
Identities = 51/223 (22%), Positives = 88/223 (39%), Gaps = 22/223 (9%)
Query: 107 PPTFLRRLQDLTVK----VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
P F++ ++D+ + VG+ F ++S + TW ++ + E+ + + DG
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIADGKD 4675
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV 222
G +TC +G + S V+ + + +EE ++ Q +
Sbjct: 4676 RKLHIIDVQLSDAGEYTCVLR-LGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ-PL 4733
Query: 223 SLECKVVGVPTPVLRWFKDSREI--KAGDVF--------ALTANAEDPTSLGTYTCEAVN 272
L C++ V W KD + + K G + ALT N D T GTYT N
Sbjct: 4734 YLSCELNKERDVV--WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN 4791
Query: 273 CMGRAYSSSKVHVVGRASREGSLKP-NSSGLSPEPPPIFTREL 314
SS V VV R+ +KP + P+ IF ++
Sbjct: 4792 A-NNLECSSCVKVV-EVIRDWLVKPIRDQHVKPKGTAIFACDI 4832
Score = 31.9 bits (69), Expect = 3.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
L + +R DTG+YT+ A N G+ + +RL V P
Sbjct: 9684 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGP 9722
Score = 31.1 bits (67), Expect = 6.1
Identities = 17/49 (34%), Positives = 24/49 (48%)
Query: 53 FVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
F T+ +L ++ A D G YT ASNA G ++ L + A ES
Sbjct: 3344 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3392
Score = 31.1 bits (67), Expect = 6.1
Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 21/190 (11%)
Query: 63 RLTVSTARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD-LTV 119
+L + + D G YT L+ N + TA++ +E E P F++ L++ +TV
Sbjct: 4677 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE---------ELPVRFVKTLEEEVTV 4727
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRW 178
G E+ + E V W ++ + ++E R+ G G +
Sbjct: 4728 VKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 4785
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLR 237
T T EN CS+ + V+ R V+ +R + +GT C + TP ++
Sbjct: 4786 TVTVENANN-LECSSCVKVV---EVIRDWLVKPIRDQHVKPKGTAIFACDIAK-DTPNIK 4840
Query: 238 WFKDSREIKA 247
WFK EI A
Sbjct: 4841 WFKGYDEIPA 4850
Score = 30.7 bits (66), Expect = 8.1
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
VS EA L++ A D G YT+ ASN GS V +EV SP
Sbjct: 8956 VSRSEAK-TELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSP 9003
>AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.
Length = 5604
Score = 80.6 bits (190), Expect = 8e-15
Identities = 68/240 (28%), Positives = 104/240 (43%), Gaps = 31/240 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
R+ +S R D G YT AG + + V L V+A E PP L+ LQ +TV+ G
Sbjct: 3204 RMFISETRQSDAGEYTF----VAGRNRSSVTLYVNAPE------PPQVLQELQPVTVQSG 3253
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF I + K++WY+ E+ L + + DG + +TC A
Sbjct: 3254 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3313
Query: 183 ENVGGRASCSAHLNVLVPKAYK--------RPEFVEELRALLTEQG-TVSLECKVVGVPT 233
+N G A+ SA L+V VP+ P + L+ +T +G +C+V G
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3373
Query: 234 PVLRWFKDSREIKAGDVFALTANAED----------PTSLGTYTCEAVNCMGRAYSSSKV 283
V W+ ++IK F +T ED P GTYT A N +G+ S++ +
Sbjct: 3374 KV-SWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3431
Score = 79.4 bits (187), Expect = 2e-14
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+PTPV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 55.2 bits (127), Expect = 3e-07
Identities = 75/315 (23%), Positives = 123/315 (39%), Gaps = 41/315 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+ DR +E RL + + R D G YT+ AG + + +L V G D
Sbjct: 3099 ITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV----VAGGNVSTAKLFVE------GRD-- 3146
Query: 109 TFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRN--ERRLLEAERVSIVRDGSFFCX 165
+R ++ V+V + R +VE ++ + WY++ E ER V +
Sbjct: 3147 VRIRSIKK-EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM 3205
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G +T A GR S L V P+ P+ ++EL+ + + G +
Sbjct: 3206 FISETRQSDAGEYTFVA----GRNRSSVTLYVNAPEP---PQVLQELQPVTVQSGKPARF 3258
Query: 226 CKVV-GVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMG 275
C V+ G P P + W+K+ + + G + L P YTCEA N G
Sbjct: 3259 CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 3318
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPP 335
A +S+ + V + P+ P PP L+D +P C+ V
Sbjct: 3319 VATTSASLSV----EVPEVVSPDQE--MPVYPPAIITPLQDTVTSEGQPARFQCR--VSG 3370
Query: 336 WPRSVVWYNKEGKVE 350
V WY+K+ K++
Sbjct: 3371 TDLKVSWYSKDKKIK 3385
Score = 54.4 bits (125), Expect = 6e-07
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 93 RLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE-- 150
RLE + E P F+ + G RF ++++ + W+ + ++++
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 151 AERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVE 210
+V I DG+ G WT A+N GR+S S L V + +P FVE
Sbjct: 1502 THKVVIKEDGTQ-SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 211 ELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
+L+ + ++G+ + ++ + G P P + W K+S
Sbjct: 1561 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNS 1593
Score = 54.4 bits (125), Expect = 6e-07
Identities = 80/341 (23%), Positives = 129/341 (37%), Gaps = 45/341 (13%)
Query: 51 DRFVSTEEAGGV-RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP- 108
D + E G V L +S + G+ G Y A N G + +++ +E PP
Sbjct: 5226 DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 5285
Query: 109 -TFLRRLQ-DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER-VSIVRDGSFFCX 165
T ++ DL +RT EI+ E +E+ + E E+ V IV F
Sbjct: 5286 VTHQHVMEFDLEHTTSSRTPSPQEIVLEVEL------SEKDVKEFEKQVKIVTVPEFTPD 5339
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSL 224
+ N+ R L + + P F+ + + E
Sbjct: 5340 HKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVF 5399
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAVNCM 274
+C V+G+PTP ++W+K+ I+ ++ + + + +L TY C AVNC+
Sbjct: 5400 KCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCV 5459
Query: 275 GRAY--------SSSKVHVVGRASR--------EGSLKPNSSG-----LSPEPPPIFTRE 313
G A S V+ + S+ E LK N + E PP F +
Sbjct: 5460 GEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKG 5519
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ D Y I C + P P +V WY K+GK+ G R
Sbjct: 5520 ISDCYAPIGTAAYFQCLVRGSPRP-TVYWY-KDGKLVQGRR 5558
Score = 50.8 bits (116), Expect = 7e-06
Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V +E G L + A D+G +T+ A N AG + V L V A E + P F+ +
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH---QVKPMFVEK 1561
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF-CXXXXXXXX 172
L+++ +K G+R V + + W +N ++ + I +G+
Sbjct: 1562 LKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTV 1621
Query: 173 XXXGRW-TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
W T TA N GR + +NV V A PE R L+ +GT
Sbjct: 1622 SQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE-----RKLIIPRGT 1666
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
E SPS E P F R+Q TV G+ F V ++ + + WY+N ++ ++R+
Sbjct: 2070 ELSPSMEAPKIF-ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYW 2128
Query: 159 DGSFFC-XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT 217
C A N+ G S A L V +A + F +EL+ ++
Sbjct: 2129 PEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV---QAKQLITFTQELQDVVA 2185
Query: 218 -EQGTV-SLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
E+ T+ + EC+ P ++W+KD E+ GD + +
Sbjct: 2186 KEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYRM 2222
Score = 48.0 bits (109), Expect = 5e-05
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 7/152 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V ++ GV +T +T R + L A ++TARV V E P PPT +
Sbjct: 896 VEVKKEVGVSITGTTVR--EERFEVLHGREAKVTETARVPAPV---EIPV--TPPTLVSG 948
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+++TV G I VTWYR + ++ + I
Sbjct: 949 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 1008
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKR 205
GR+TC+A N G S S +L V V + +++
Sbjct: 1009 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 1040
Score = 48.0 bits (109), Expect = 5e-05
Identities = 29/101 (28%), Positives = 44/101 (43%)
Query: 98 AEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
A E E PP+F+ L V T F+VE+ V WYRN+ L ER+ +
Sbjct: 5173 AIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKME 5232
Query: 158 RDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
R G+ G + C A N+ G A A+++++
Sbjct: 5233 RVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 41.5 bits (93), Expect = 0.004
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAV 271
V+ CK+ G P P + W+KD + IK G+ + + + SL G YT A
Sbjct: 1308 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1367
Query: 272 NCMGRAYSSSKVHV 285
N G A S K++V
Sbjct: 1368 NIKGNAICSGKLYV 1381
Score = 41.1 bits (92), Expect = 0.006
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 10/102 (9%)
Query: 206 PEFVEEL-RALLTEQGTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P F+E L + + E T+ +V G+P P ++W+++ + + G+V +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEI 5242
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKP 297
+ G Y C AVN +G A S + V ++ + R +L P
Sbjct: 5243 SNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPP 5284
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS-FF 163
E PP F++ + D +GT F + S V WY+ + +L++ R ++ G+ F
Sbjct: 5511 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYK-DGKLVQGRRFTVEESGTGFH 5569
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G + C A N G A A L +
Sbjct: 5570 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 39.1 bits (87), Expect = 0.023
Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL ++ + D G YT + + + S +L+V A + + L++LTV
Sbjct: 2675 RLIIAATKLDDIGEYTYKVATSKTS----AKLKVEAVK---------IKKTLKNLTVTET 2721
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
F VE+ V W +N L E+ +I G+ + +
Sbjct: 2722 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL 2781
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
GR SA L+V K K+P+ V L E TV+ E V PV +WF S
Sbjct: 2782 ----GRLGASARLHVETVKIIKKPKDVTAL-----ENATVAFEVSVSHDTVPV-KWFHKS 2831
Query: 243 REIKAGDVFALTA 255
EIK D L +
Sbjct: 2832 VEIKPSDKHRLVS 2844
Score = 38.7 bits (86), Expect = 0.031
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALT---------- 254
P V L+ + +G +V+LEC + G P+P + W+++ +I++ F +T
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 255 --ANAEDPTSLGTYTCEAVNCMGRAYSS 280
A AED G +TC AVN G +S
Sbjct: 1003 REAFAEDS---GRFTCSAVNEAGTVSTS 1027
Score = 35.5 bits (78), Expect = 0.28
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 14/108 (12%)
Query: 203 YKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAG---------DVFA 252
Y +P F ++L +G V C+++ PTP + WF ++R I G D+
Sbjct: 3501 YFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHH 3560
Query: 253 LTANAE----DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLK 296
+++ E G+Y A+N G A S++ + V+ + E L+
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLE 3608
Score = 33.9 bits (74), Expect = 0.87
Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 11/100 (11%)
Query: 206 PEFVEEL--RALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALT 254
P+ ++E+ A E ++ LEC + G P PV+ WF++ +K F L
Sbjct: 4158 PKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLY 4217
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ G Y C A N G S S + V RE S
Sbjct: 4218 IKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENS 4257
Score = 32.7 bits (71), Expect = 2.0
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 277 AYSSSK-VHVVGRASREGSLKPNSSGLSPEP-PPIFTRELEDQYVRICEPFTLSCQIVVP 334
A+S S+ + A++ + + +S+ PE P FT++L +YV EP +C+++
Sbjct: 3471 AFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIAC 3530
Query: 335 PWPRSVVWYNKEGKVEAGER 354
P P + W++ + G R
Sbjct: 3531 PTP-EMTWFHNNRPIPTGLR 3549
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
Score = 31.9 bits (69), Expect = 3.5
Identities = 26/111 (23%), Positives = 41/111 (36%), Gaps = 5/111 (4%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP+FL+ ++ V G F+ + VTWY N+ + + I ++
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILT 4002
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-----KAYKRPEFVEEL 212
G TC N G ++ L V KA+K P F + L
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYL 4053
Score = 31.1 bits (67), Expect = 6.1
Identities = 17/49 (34%), Positives = 24/49 (48%)
Query: 53 FVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
F T+ +L ++ A D G YT ASNA G ++ L + A ES
Sbjct: 3390 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3438
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 80.2 bits (189), Expect = 1e-14
Identities = 68/240 (28%), Positives = 104/240 (43%), Gaps = 31/240 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
R+ +S R D G YT AG + + V L V+A E PP L+ LQ +TV+ G
Sbjct: 3158 RMFISETRQSDAGEYTF----VAGRNRSSVTLYVNAPE------PPQVLQELQPVTVQSG 3207
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF I + K++WY+ E+ L + + DG + +TC A
Sbjct: 3208 KPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3267
Query: 183 ENVGGRASCSAHLNVLVPKAYK--------RPEFVEELRALLTEQG-TVSLECKVVGVPT 233
+N G A+ SA L+V VP+ P + L+ +T +G +C+V G
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3327
Query: 234 PVLRWFKDSREIKAGDVFALTANAED----------PTSLGTYTCEAVNCMGRAYSSSKV 283
V W+ ++IK F +T ED P GTYT A N +G+ S++ +
Sbjct: 3328 KV-SWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANL 3385
Score = 77.4 bits (182), Expect = 7e-14
Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+P PV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 9/196 (4%)
Query: 15 VRRSATLDIHPQYDRWRHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDT 74
VR T+ +HP+ HV + K + G + D ++ + G +LT+++ T D
Sbjct: 25210 VRFGVTITVHPE-----PHVTWYKSGQKIKPGDN-DKKYTFESDKGLYQLTINSVTTDDD 25263
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIIS 133
YT+ A N G D+ + +L V+ P+ P F R L + + G F + +
Sbjct: 25264 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 25323
Query: 134 STECKVTWYRNERRLLEAERVSIVRDG-SFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
+ W ++ + L + I+ +G ++ G + TA N G SC
Sbjct: 25324 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQ 25383
Query: 193 AHLNVLVPKAYKRPEF 208
AHL V YK+ EF
Sbjct: 25384 AHLQV-ERLRYKKQEF 25398
Score = 66.1 bits (154), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 63.7 bits (148), Expect = 9e-10
Identities = 53/199 (26%), Positives = 77/199 (38%), Gaps = 18/199 (9%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGS 161
E PP F L + T VG RF V I E VTWY++ +++ + + + D
Sbjct: 25190 ERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG 25249
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV----PKAYKRPEFVEELRALLT 217
+ +T A N G SC A L V + + RP F L
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAEC 25309
Query: 218 EQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALTANAEDPTSLGTY 266
++G +V E +V G+P P L+W KD + + G D +AL P G Y
Sbjct: 25310 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25369
Query: 267 TCEAVNCMGRAYSSSKVHV 285
A N G + + V
Sbjct: 25370 RVTATNTAGSTSCQAHLQV 25388
Score = 62.1 bits (144), Expect = 3e-09
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P F++ + + + +G V +I + K+ W+ N L + V DG
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNV--------------LVPKAYKR------PE 207
G +TC A N G+ CSA+L + V K+ ++ P
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 208 FVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKDSREIKAGDVFALTAN--------AE 258
F++EL+ + QG ++ E VVG P P + WFK+++++ + + N
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636
Query: 259 DP--TSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
DP G Y C+A N +G + ++++ V+ + + P + +PE P F
Sbjct: 3637 DPQREDSGLYICKAENMLGESTCAAELLVL-LEDTDMTDTPCKAKSTPEAPEDF 3689
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 7/157 (4%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGD-TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
D++F ++ L + T D G Y +A N +G +L V +P
Sbjct: 4284 DEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP------ 4337
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
R+++ L V +G +F EI S+ + W++ R + E+++ SI
Sbjct: 4338 VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEIL 4397
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKR 205
G +TC A N G SC+A L V VP K+
Sbjct: 4398 RTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4434
Score = 56.4 bits (130), Expect = 1e-07
Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 15/178 (8%)
Query: 76 VYTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEI 131
V+TL + D V+L ++ + E P F + L+D TV+ G T L
Sbjct: 5752 VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGA-TAVLECE 5810
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+S KV W++N +L++++ IV DG +TC A++ + SC
Sbjct: 5811 VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSC 5868
Query: 192 SAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG 248
+LNV+ P EF+ L L + E+ EC++ V +WFKD EIK G
Sbjct: 5869 --NLNVVPPHV----EFLRPLTDLQVREKEMARFECELSRENAKV-KWFKDGAEIKKG 5919
Score = 54.8 bits (126), Expect = 4e-07
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 93 RLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE-- 150
RLE + E P F+ + G RF ++++ + W+ + ++++
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDY 1455
Query: 151 AERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVE 210
+V I DG+ G WT A+N GR+S S L V + +P FVE
Sbjct: 1456 THKVVIKEDGTQ-SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514
Query: 211 ELRALLTEQGT-VSLECKVVGVPTPVLRWFKDS 242
+L+ + ++G+ + ++ + G P P + W K+S
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNS 1547
Score = 54.0 bits (124), Expect = 8e-07
Identities = 74/315 (23%), Positives = 123/315 (39%), Gaps = 41/315 (13%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+ DR +E RL + + R D G YT+ AG + + +L V G D
Sbjct: 3053 ITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV----VAGGNVSTAKLFVE------GRD-- 3100
Query: 109 TFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRN--ERRLLEAERVSIVRDGSFFCX 165
+R ++ V+V + R +VE ++ + WY++ E ER V +
Sbjct: 3101 VRIRSIKK-EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM 3159
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G +T A GR S L V P+ P+ ++EL+ + + G +
Sbjct: 3160 FISETRQSDAGEYTFVA----GRNRSSVTLYVNAPEP---PQVLQELQPVTVQSGKPARF 3212
Query: 226 CKVV-GVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAVNCMG 275
C ++ G P P + W+K+ + + G + L P YTCEA N G
Sbjct: 3213 CAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYG 3272
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPP 335
A +S+ + V + P+ P PP L+D +P C+ V
Sbjct: 3273 VATTSASLSV----EVPEVVSPDQE--MPVYPPAIITPLQDTVTSEGQPARFQCR--VSG 3324
Query: 336 WPRSVVWYNKEGKVE 350
V WY+K+ K++
Sbjct: 3325 TDLKVSWYSKDKKIK 3339
Score = 53.6 bits (123), Expect = 1e-06
Identities = 39/183 (21%), Positives = 72/183 (39%), Gaps = 3/183 (1%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
A N G R R +S + + + P + ++D+T K+G + +I+ +
Sbjct: 24010 AENETGLSRPR-RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK 24068
Query: 141 WYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
WYR + L+++ + + DG G +TC A N G S+ L +L
Sbjct: 24069 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQA 24127
Query: 201 KAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDP 260
P + + + T+ L +G P P + WF + ++ + + N E
Sbjct: 24128 TPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITI-ENTEHY 24186
Query: 261 TSL 263
T L
Sbjct: 24187 THL 24189
Score = 51.2 bits (117), Expect = 5e-06
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+ A D G+ T + G + L +S E S D P F+ + + + G
Sbjct: 26597 LTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS----DAPAFISQPRSQNINEGQ 26652
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F EI ++ W++N + + VSI R + + G++T A+
Sbjct: 26653 NVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAK 26712
Query: 184 NVGGRASCSAHLNVL 198
N G+ S +A L VL
Sbjct: 26713 NFRGQCSATASLMVL 26727
Score = 50.8 bits (116), Expect = 7e-06
Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V +E G L + A D+G +T+ A N AG + V L V A E + P F+ +
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH---QVKPMFVEK 1515
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF-CXXXXXXXX 172
L+++ +K G+R V + + W +N ++ + I +G+
Sbjct: 1516 LKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTV 1575
Query: 173 XXXGRW-TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
W T TA N GR + +NV V A PE R L+ +GT
Sbjct: 1576 SQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE-----RKLIIPRGT 1620
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
E SPS E P F R+Q TV G+ F V ++ + + WY+N ++ ++R+
Sbjct: 2024 ELSPSMEAPKIF-ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYW 2082
Query: 159 DGSFFC-XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT 217
C A N+ G S A L V +A + F +EL+ ++
Sbjct: 2083 PEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV---QAKQLITFTQELQDVVA 2139
Query: 218 -EQGTV-SLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
E+ T+ + EC+ P ++W+KD E+ GD + +
Sbjct: 2140 KEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYRM 2176
Score = 50.4 bits (115), Expect = 9e-06
Identities = 62/242 (25%), Positives = 92/242 (38%), Gaps = 32/242 (13%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA 98
N K + A L +E G + L + R TG QA+N S RV+ V
Sbjct: 5641 NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIG 5700
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
LR L+D+TV G F E+ S + V WY ++L +++V
Sbjct: 5701 -----------LLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKVVPRS 5748
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTE 218
+G G TA++ H N+ V + EF + L E
Sbjct: 5749 EGKVHTLTLRDVKLEDAGEVQLTAKDF------KTHANLFVKEP--PVEFTKPLEDQTVE 5800
Query: 219 QG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE---------DPTSLGTYTC 268
+G T LEC+V V +WFK+ EI + + A+ P + TYTC
Sbjct: 5801 EGATAVLECEVSRENAKV-KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5859
Query: 269 EA 270
+A
Sbjct: 5860 DA 5861
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
Query: 183 ENVGGRASCSAHLNVLVPKA---YKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRW 238
EN+GG + S + PK+ + P F EELR L + Q +L CKV G P P+++W
Sbjct: 24405 ENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKW 24464
Query: 239 FKDSREIKA 247
++ +EI A
Sbjct: 24465 YRQGKEIIA 24473
Score = 48.8 bits (111), Expect = 3e-05
Identities = 56/238 (23%), Positives = 86/238 (36%), Gaps = 20/238 (8%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
+S + + A V+++ AE ED P L D + G I ++ E V
Sbjct: 4217 SSESGTEEVATVKIQ-EAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE--VN 4273
Query: 141 WYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
WY + + E+ ++D ++ G + C A N G+ + SA L V+
Sbjct: 4274 WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 4333
Query: 200 PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD---------V 250
A +E L L C++ P +WFK REI D +
Sbjct: 4334 RAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4391
Query: 251 FALTANAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASREGSLKPNSSGLSPEP 306
+L G YTC+A N G ++ V V G + L P PEP
Sbjct: 4392 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER---KPEP 4446
Score = 48.0 bits (109), Expect = 5e-05
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 7/152 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
V ++ GV +T +T R + L A ++TARV V E P PPT +
Sbjct: 850 VEVKKEVGVSITGTTVR--EERFEVLHGREAKVTETARVPAPV---EIPV--TPPTLVSG 902
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+++TV G I VTWYR + ++ + I
Sbjct: 903 LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 962
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKR 205
GR+TC+A N G S S +L V V + +++
Sbjct: 963 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 994
Score = 47.6 bits (108), Expect = 7e-05
Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 6/152 (3%)
Query: 51 DRFVST-EEAGGVRLTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPP 108
D++V+ E ++ V+ G Y ++ N G S +R E+ A ++ E P
Sbjct: 7135 DKWVACGEPVAETKMEVTGLEEGKWYAYRVKTLNRQGASKPSRPTEEIQAVDTQ--EAPE 7192
Query: 109 TFL--RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
FL + L LTVK GT+ + E K+TW + + L + +R++I
Sbjct: 7193 IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVT 7252
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
G + A NV GRA+ +NVL
Sbjct: 7253 IVDSKRSDTGTYIIEAVNVCGRATAVVEVNVL 7284
Score = 47.2 bits (107), Expect = 9e-05
Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 9/193 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP---PTF 110
V+TEE +V G + ++ N G E+S +P + P P F
Sbjct: 24377 VTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWS---EISEPITPKSDVPIQAPHF 24433
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD--GSFFCXXXX 168
L++L V+ + + ++ + V WYR + ++ +++ G +
Sbjct: 24434 KEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIA 24493
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECK 227
+ A N GG S +A L V VP P+ +E + A+ +G VS++
Sbjct: 24494 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIP 24553
Query: 228 VVGVPTPVLRWFK 240
G P PV+ W K
Sbjct: 24554 FSGKPDPVITWQK 24566
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/138 (29%), Positives = 61/138 (44%), Gaps = 11/138 (7%)
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXX 169
FL L+D+T K F VE+ S +V W++N++RL VS+ +G
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVEL-SHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKD 5492
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALL-TEQGTVSLECKV 228
+ E +G S A L VL Y F +L+ E+ V L+C++
Sbjct: 5493 LSIDDTSQ--IRVEAMG--MSSEAKLTVLEGDPY----FTGKLQDYTGVEKDEVILQCEI 5544
Query: 229 VGVPTPVLRWFKDSREIK 246
PV +WFKD +EIK
Sbjct: 5545 SKADAPV-KWFKDGKEIK 5561
Score = 46.4 bits (105), Expect = 2e-04
Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 13/180 (7%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+++ G R I +T+ K W N L +E GS G
Sbjct: 26551 MSINEGQRLVLKANIAGATDVK--WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26608
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV 235
TC ++ G C L L + P F+ + R+ +G V C++ G P+P
Sbjct: 26609 ILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667
Query: 236 LRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ WFK++ I ++ +V++L + G YT +A N G+ +++ + V+
Sbjct: 26668 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 45.2 bits (102), Expect = 4e-04
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 10/88 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P +E++ + T+ G + L C++VG P P ++W++ +E+ G LT
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
E+ G YTC A N +G +SSK+
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKL 24123
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 1/113 (0%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
DT + E G PP FL+ L+ + G F ++ VTW++ ++
Sbjct: 3555 DTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ 3614
Query: 148 LLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
L + +I+ + G + C AEN+ G ++C+A L VL+
Sbjct: 3615 LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3667
Score = 42.3 bits (95), Expect = 0.002
Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 21/193 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ ++ D GVYT + G T+ RL V+ F+ L+D TVK G
Sbjct: 5044 LVINDSQFDDEGVYTAEVE---GKKTS-ARLFVTGIRLK-------FMSPLEDQTVKEGE 5092
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F+ E+ S + V W++N+ +L + V I +G + +
Sbjct: 5093 TATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK 5151
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
+ S +A L VL Y + ++ E+ ++L+C+V PV +WFKD
Sbjct: 5152 EL----SSTAQLKVLEADPYFTVKLHDKTAV---EKDEITLKCEV-SKDVPV-KWFKDGE 5202
Query: 244 EIKAGDVFALTAN 256
EI +++ A+
Sbjct: 5203 EIVPSPKYSIKAD 5215
Score = 41.5 bits (93), Expect = 0.004
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAV 271
V+ CK+ G P P + W+KD + IK G+ + + + SL G YT A
Sbjct: 1262 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1321
Query: 272 NCMGRAYSSSKVHV 285
N G A S K++V
Sbjct: 1322 NIKGNAICSGKLYV 1335
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 15/127 (11%)
Query: 196 NVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-- 252
NV+ +P E ++ +G +S+ VP P + W KD +E+KA D
Sbjct: 7880 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 7939
Query: 253 ---LTANAEDPTSL----GTYTCEAVNCMGRAYSSSKVHVVG-----RASREGSLKPNSS 300
++A+ E P S+ G YT N +G A +S V V+G + + + +S
Sbjct: 7940 NDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSC 7999
Query: 301 GLSPEPP 307
L+ EPP
Sbjct: 8000 KLTWEPP 8006
Score = 41.5 bits (93), Expect = 0.004
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+TV+VG R L + E +TW + + L+ +RV +++D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 177 RWTCTAENVGGRASCSAHLNVL 198
++ +A+N G A SA +NVL
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVL 11502
Score = 41.5 bits (93), Expect = 0.004
Identities = 26/120 (21%), Positives = 43/120 (35%), Gaps = 4/120 (3%)
Query: 82 SNAAGSDTARVRLEVSAEESPSGEDP----PTFLRRLQDLTVKVGTRTRFLVEIISSTEC 137
S SD V+ + P +P P + LQD TV + +F V+
Sbjct: 26325 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 26384
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
W ++ + + + + + D F G +TCT +N G S S L +
Sbjct: 26385 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Score = 41.1 bits (92), Expect = 0.006
Identities = 25/109 (22%), Positives = 43/109 (39%)
Query: 89 TARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL 148
T+ + EV +++ + + P R++ V G TRF++ + S +V WY N L
Sbjct: 25858 TSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL 25917
Query: 149 LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
E+ ++ G + N G AS A L+V
Sbjct: 25918 QESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWF---------KDSREIKAGDVFALTA 255
P F++E+ G V+ L V+G+P P ++WF D + + GD +L
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASR----EGSLKPNSSGLSPEPPPI 309
G YTC A N G+ S+ K++ G + E ++ + L PP
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
F +EL+ P +V P P +V W+ KE K
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAP-TVTWF-KENK 3613
Score = 39.1 bits (87), Expect = 0.023
Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL ++ + D G YT + + + S +L+V A + + L++LTV
Sbjct: 2629 RLIIAATKLDDIGEYTYKVATSKTS----AKLKVEAVK---------IKKTLKNLTVTET 2675
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
F VE+ V W +N L E+ +I G+ + +
Sbjct: 2676 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL 2735
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
GR SA L+V K K+P+ V L E TV+ E V PV +WF S
Sbjct: 2736 ----GRLGASARLHVETVKIIKKPKDVTAL-----ENATVAFEVSVSHDTVPV-KWFHKS 2785
Query: 243 REIKAGDVFALTA 255
EIK D L +
Sbjct: 2786 VEIKPSDKHRLVS 2798
Score = 39.1 bits (87), Expect = 0.023
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
TK + ++ +E+ GG L + T D+G+YT N+AGS ++ +L + A +
Sbjct: 26389 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26448
Query: 101 SPSGEDPPTFLRRLQDLT--VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
+ T ++ ++T K + + + S E K++ +++ +L E S V
Sbjct: 26449 DTEAQKVST--QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 26505
Score = 38.7 bits (86), Expect = 0.031
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALT---------- 254
P V L+ + +G +V+LEC + G P+P + W+++ +I++ F +T
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 255 --ANAEDPTSLGTYTCEAVNCMGRAYSS 280
A AED G +TC AVN G +S
Sbjct: 957 REAFAEDS---GRFTCSAVNEAGTVSTS 981
Score = 38.7 bits (86), Expect = 0.031
Identities = 31/138 (22%), Positives = 55/138 (39%), Gaps = 5/138 (3%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLE-VSAEESPSGEDPPTFLRRLQD-LTVK 120
+ TV + GDT Y + A N G + ++ ++ + PPT +D LT++
Sbjct: 10278 KYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA---PPTLHLDFRDKLTIR 10334
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
VG + KV+W+++E +LE +R I + G++
Sbjct: 10335 VGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCV 10394
Query: 181 TAENVGGRASCSAHLNVL 198
EN G +NV+
Sbjct: 10395 VVENSTGSRKGFCQVNVV 10412
Score = 38.3 bits (85), Expect = 0.040
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 17/124 (13%)
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFK 240
A N G + SA + + P ++ + E+GT V++ K+ GVP P L WFK
Sbjct: 9596 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9655
Query: 241 ------DSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVH 284
D++E + D L + G YT AVN +G A +++
Sbjct: 9656 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9715
Query: 285 VVGR 288
V+GR
Sbjct: 9716 VLGR 9719
Score = 38.3 bits (85), Expect = 0.040
Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 3/137 (2%)
Query: 65 TVSTARTGDTGVYTLQASNAAG--SDTARVRLEVSAEESPSGEDPPTFLRRLQDL-TVKV 121
TV+ GDT + + A NAAG S + V+ + + R DL T++
Sbjct: 22505 TVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRA 22564
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
G+ + E K+ W + ++ L E+VS+ G G++T T
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 22624
Query: 182 AENVGGRASCSAHLNVL 198
+N G + S + VL
Sbjct: 22625 VKNASGTKAVSVMVKVL 22641
Score = 37.5 bits (83), Expect = 0.071
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 16/143 (11%)
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGT-VSLECKVVGVPTPVLRW 238
TA N+ + S + +L R + +++LLT + GT V L+ V G P P + W
Sbjct: 12773 TAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSW 12832
Query: 239 FKDSREIK--AGDVFALTAN-------AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA 289
KD +K G A+ N + + G YT A N G ++ K+ V+ +
Sbjct: 12833 KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 12892
Query: 290 SREGSLKPNS-----SGLSPEPP 307
S+K N + LS EPP
Sbjct: 12893 GPPASVKINKMYSDRAMLSWEPP 12915
Score = 37.5 bits (83), Expect = 0.071
Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 6/146 (4%)
Query: 58 EAGGVR-LTVSTARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRL 114
EAG + LT + R + Y ++A N AG R + P E P L +
Sbjct: 22097 EAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIE-PTADLTGI 22155
Query: 115 --QDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
Q +T K G+ V I KVTW E RL E +RVSI
Sbjct: 22156 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMR 22215
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVL 198
GR+ T EN G + S + V+
Sbjct: 22216 GDSGRYFLTLENTAGVKTFSVTVVVI 22241
Score = 36.7 bits (81), Expect = 0.12
Identities = 40/158 (25%), Positives = 59/158 (37%), Gaps = 3/158 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
E + V+ R G T + + A NAAG SD A V V ++ + +
Sbjct: 10670 ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAR 10729
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
+ +KVG R I KVTW + +R R+ + GS
Sbjct: 10730 EQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKL--EIRNAAHEDG 10787
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR 213
G ++ T EN G + S + VL R V E+R
Sbjct: 10788 GIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIR 10825
Score = 35.9 bits (79), Expect = 0.22
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
E P F+ L+D TV F ++ S + V WYRN R + E ++ +DGS
Sbjct: 6323 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYKFEKDGS 6378
Score = 35.9 bits (79), Expect = 0.22
Identities = 42/202 (20%), Positives = 79/202 (39%), Gaps = 12/202 (5%)
Query: 50 DDRFVSTEEAGGVRLT---VSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGE 105
++ + + G VR T VS + G + + A N AG + + V A++
Sbjct: 20713 EEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAP 20772
Query: 106 DPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
+ + + K G + L+ VTW ++E+ L R SI S
Sbjct: 20773 EIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLL 20832
Query: 166 XXXXXXXXXXGRWTCTAEN-VGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G++ T EN VG S + + VL P ++L+ +GTV+L
Sbjct: 20833 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVL-----DTPAACQKLQVKHVSRGTVTL 20887
Query: 225 --ECKVVGVPTPVLRWFKDSRE 244
+ ++ +P++ + + R+
Sbjct: 20888 LWDPPLIDGGSPIINYVIEKRD 20909
Score = 35.5 bits (78), Expect = 0.28
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 21/242 (8%)
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+D VK F E+ ++ K W+RNE + ++ + I++ +
Sbjct: 6149 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGTVSLECKVVGVP 232
+ + N G SA N++V + R VE L+ + T E+ +V+ CKV +
Sbjct: 6208 DQANYNVSLTNHRGENVKSA-ANLIVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL- 6263
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
L+W K+ E+ + + + + +C + ++V
Sbjct: 6264 NVTLKWTKNGEEVPFDNRVSYRVDKY------KHMLTIKDC---GFPDEGEYIV----TA 6310
Query: 293 GSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAG 352
G K + L E P F LEDQ V + SCQ+ +V WY +++ G
Sbjct: 6311 GQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQL--SREKANVKWYRNGREIKEG 6368
Query: 353 ER 354
++
Sbjct: 6369 KK 6370
Score = 35.5 bits (78), Expect = 0.28
Identities = 37/199 (18%), Positives = 72/199 (36%), Gaps = 5/199 (2%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
V+ + G T + ++A N G + + +E ++ ++ L VK GT
Sbjct: 10972 VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTV 11031
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
RF I W + + E ++ D G + T N
Sbjct: 11032 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA 11091
Query: 186 GGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSRE 244
G + + HL VL VP P + + + E T+S + +PV+ + + ++
Sbjct: 11092 AGSKTVAVHLTVLDVPGPPTGPINILD---VTPEHMTISWQPPKDDGGSPVINYIVEKQD 11148
Query: 245 IKAGDVFALTANAEDPTSL 263
+ D + + ++ T L
Sbjct: 11149 TRK-DTWGVVSSGSSKTKL 11166
Score = 35.5 bits (78), Expect = 0.28
Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 5/149 (3%)
Query: 96 VSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVS 155
+ AE P D ++ L LTVK GT + V+W ++ L AE +
Sbjct: 12789 ILAENVPPRIDLSVAMKSL--LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK 12846
Query: 156 IVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL 215
+ + G +T TAEN G S + L VL P ++ +
Sbjct: 12847 MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG---PPASVKINKM 12903
Query: 216 LTEQGTVSLECKVVGVPTPVLRWFKDSRE 244
+++ +S E + + + + D RE
Sbjct: 12904 YSDRAMLSWEPPLEDGGSEITNYIVDKRE 12932
Score = 35.1 bits (77), Expect = 0.38
Identities = 29/128 (22%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 205 RPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANA------ 257
+P V L+ +V+ K G P P W KD + I G + L+ +
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 258 ---EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS--LKPNSSGLSPEPPPIFTR 312
D + G YTC N G SS K+ + E +S ++P+ +
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 26473
Query: 313 ELEDQYVR 320
E+ + +R
Sbjct: 26474 EISQKALR 26481
Score = 34.3 bits (75), Expect = 0.66
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 13/90 (14%)
Query: 206 PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL-- 263
PE+ + L ++ ++ ++ V G P P + WFKD EI+ +T N TSL
Sbjct: 21465 PEYFDGL--IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-NVLGSTSLFV 21521
Query: 264 --------GTYTCEAVNCMGRAYSSSKVHV 285
G YT EA N G A + KV V
Sbjct: 21522 RDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 34.3 bits (75), Expect = 0.66
Identities = 48/210 (22%), Positives = 80/210 (38%), Gaps = 13/210 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV T D GVYT A+N G +L + A +P P L+ + VG+
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA--TPQFH-PGYPLK--EKYYGAVGS 24147
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF-FCXXXXXXXXXXXGRWTCTA 182
R V I +TW+ ++ L +E ++I + G++
Sbjct: 24148 TLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 24207
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
NV G + A L+V + +P + ALL +S + + + + +
Sbjct: 24208 SNVFG--TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 24265
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVN 272
E K G + L ++A + TC VN
Sbjct: 24266 CEAKEGAEWQLVSSA-----ISVTTCRIVN 24290
Score = 33.5 bits (73), Expect = 1.1
Identities = 39/182 (21%), Positives = 70/182 (38%), Gaps = 21/182 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G Y + ++ +V E++AE F+ + Q+L + G
Sbjct: 6022 LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAE----------FISKPQNLEILEGE 6070
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ F+ I S V W R+++ L ++ ++ DG G +
Sbjct: 6071 KAEFVCSI-SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV- 6128
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G A +AHL V+ P +++ R + EQ V C+ V +WF++
Sbjct: 6129 ---GAARAAAHLTVIEKLRIVVP--LKDTR--VKEQQEVVFNCE-VNTEGAKAKWFRNEE 6180
Query: 244 EI 245
I
Sbjct: 6181 AI 6182
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/43 (44%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
V T+ V LT+ DTG Y + SNAAGS T V L V
Sbjct: 11062 VETDNFSSV-LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 33.5 bits (73), Expect = 1.1
Identities = 18/82 (21%), Positives = 36/82 (43%), Gaps = 9/82 (10%)
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTYTCEAV 271
+V L + G P P + W+KD +E++ D+ ++ D + G Y +
Sbjct: 20392 SVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLR 20451
Query: 272 NCMGRAYSSSKVHVVGRASREG 293
N M A ++ +V ++ + G
Sbjct: 20452 NAMASASATIRVQILDKPGPPG 20473
Score = 33.1 bits (72), Expect = 1.5
Identities = 38/195 (19%), Positives = 71/195 (36%), Gaps = 5/195 (2%)
Query: 14 IVRRSATLDIHPQYDRWRHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGD 73
+ + SATL P + +I++ + + DR+ + L V+ + G
Sbjct: 12313 MTKNSATLAWLPPLRDGGAKIDGYIISYREEEQPA--DRWTEYSVVKDLSLVVTGLKEGK 12370
Query: 74 TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIIS 133
+ + A NA G R V E+ PP L Q +T+K G + R +
Sbjct: 12371 KYKFRVAARNAVGVSLPREAEGVY--EAKEQLLPPKILMPEQ-ITIKAGKKLRIEAHVYG 12427
Query: 134 STECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSA 193
W + E ++ + +++ + S G ++ TAEN G +
Sbjct: 12428 KPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKI 12487
Query: 194 HLNVLVPKAYKRPEF 208
+ V+ +P F
Sbjct: 12488 KVVVMDAPGPPQPPF 12502
Score = 33.1 bits (72), Expect = 1.5
Identities = 29/139 (20%), Positives = 53/139 (38%), Gaps = 4/139 (2%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ G+ V G+ + + A N+AG R V +E P
Sbjct: 14512 DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTML--PELD 14569
Query: 111 LRRL-QDLTV-KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
LR + Q L + K G + + ++ + VTW + ++ L + +RV+ +
Sbjct: 14570 LRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNIN 14629
Query: 169 XXXXXXXGRWTCTAENVGG 187
G + TA N+ G
Sbjct: 14630 ECVRSDSGPYPLTARNIVG 14648
Score = 33.1 bits (72), Expect = 1.5
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
T G L V A GVYT++A NA+GS A ++++V
Sbjct: 21511 TNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 32.7 bits (71), Expect = 2.0
Identities = 32/127 (25%), Positives = 47/127 (37%), Gaps = 10/127 (7%)
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPTPVLR 237
C A G A + V Y E E + + + G + L + G P P+ +
Sbjct: 23613 CNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICK 23672
Query: 238 WFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA- 289
W K+ ++I + A L D GTY N G+ KV V+G
Sbjct: 23673 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPN 23732
Query: 290 SREGSLK 296
S EG L+
Sbjct: 23733 SPEGPLE 23739
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 10/90 (11%)
Query: 209 VEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANAEDP 260
V+ L L + GT + L V G P P + W K +K + T D
Sbjct: 7197 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS 7256
Query: 261 --TSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
+ GTY EAVN GRA + +V+V+ +
Sbjct: 7257 KRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286
Score = 31.9 bits (69), Expect = 3.5
Identities = 51/223 (22%), Positives = 88/223 (39%), Gaps = 22/223 (9%)
Query: 107 PPTFLRRLQDLTVK----VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
P F++ ++D+ + VG+ F ++S + TW ++ + E+ + + DG
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIADGKD 4675
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV 222
G +TC +G + S V+ + + +EE ++ Q +
Sbjct: 4676 RKLHIIDVQLSDAGEYTCVLR-LGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ-PL 4733
Query: 223 SLECKVVGVPTPVLRWFKDSREI--KAGDVF--------ALTANAEDPTSLGTYTCEAVN 272
L C++ V W KD + + K G + ALT N D T GTYT N
Sbjct: 4734 YLSCELNKERDVV--WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN 4791
Query: 273 CMGRAYSSSKVHVVGRASREGSLKP-NSSGLSPEPPPIFTREL 314
SS V VV R+ +KP + P+ IF ++
Sbjct: 4792 A-NNLECSSCVKVV-EVIRDWLVKPIRDQHVKPKGTAIFACDI 4832
Score = 31.9 bits (69), Expect = 3.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
L + +R DTG+YT+ A N G+ + +RL V P
Sbjct: 9684 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGP 9722
Score = 31.5 bits (68), Expect = 4.6
Identities = 25/120 (20%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 65 TVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVK 120
T S + + +++ + + DT+++R+E S + E P F +LQD T
Sbjct: 5474 TRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGV 5533
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
EI S + V W+++ + + ++ I DG G++TC
Sbjct: 5534 EKDEVILQCEI-SKADAPVKWFKDGKEIKPSKNAVIKTDGKKRMLILKKALKSDIGQYTC 5592
Score = 31.1 bits (67), Expect = 6.1
Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 21/190 (11%)
Query: 63 RLTVSTARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD-LTV 119
+L + + D G YT L+ N + TA++ +E E P F++ L++ +TV
Sbjct: 4677 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE---------ELPVRFVKTLEEEVTV 4727
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRW 178
G E+ + E V W ++ + ++E R+ G G +
Sbjct: 4728 VKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 4785
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLR 237
T T EN CS+ + V+ R V+ +R + +GT C + TP ++
Sbjct: 4786 TVTVENANN-LECSSCVKVV---EVIRDWLVKPIRDQHVKPKGTAIFACDIAK-DTPNIK 4840
Query: 238 WFKDSREIKA 247
WFK EI A
Sbjct: 4841 WFKGYDEIPA 4850
Score = 30.7 bits (66), Expect = 8.1
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
VS EA L++ A D G YT+ ASN GS V +EV SP
Sbjct: 8956 VSRSEAK-TELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSP 9003
>BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein.
Length = 637
Score = 79.4 bits (187), Expect = 2e-14
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+PTPV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
>BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein.
Length = 558
Score = 79.4 bits (187), Expect = 2e-14
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+PTPV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
>BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein.
Length = 305
Score = 79.4 bits (187), Expect = 2e-14
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 14/192 (7%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER--VSIVRDGSFFCX 165
PTF + LQ + V G+ F I +V+W+R+ + + + V I
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
GR++ A N G+A+ +A L LV P FV+ L+++ QG+ V L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 225 ECKVVGVPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMG 275
+ +V G+PTPV+++++D EI++ GD+++L P GTY+ A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 276 RAYSSSKVHVVG 287
RA S++++ V G
Sbjct: 184 RATSTAELLVQG 195
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ ++G Y+L+A+N +G T+ L V AE +P P F++RLQ +TV
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAP-----PNFVQRLQSMTV 115
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ G++ R V + V +YR+ + + I ++G + G ++
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 180 CTAENVGGRASCSAHLNV 197
A N GRA+ +A L V
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 32.3 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 47 ASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGED 106
+SLD F ++E L ++ A D+G Y++ A+N+ G T+ L V EE +
Sbjct: 146 SSLD--FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKK 203
Query: 107 PPTFLRRLQ 115
T + Q
Sbjct: 204 TKTIVSTAQ 212
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 78.2 bits (184), Expect = 4e-14
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 22/243 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----------PS 103
ST EAG L + A D G YT A NA G + + V ++S PS
Sbjct: 559 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
P FL+ L DL V G++ V++ + +V W N + E+E + G+
Sbjct: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TV 222
G +TC A N G A L V P +P F+ + R++ G +V
Sbjct: 679 SLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
Query: 223 SLECKVVGVPTPVLRWFKDSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVN 272
+ C + G P P + W +D + ++ DVF L P G Y N
Sbjct: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Query: 273 CMG 275
+G
Sbjct: 799 RVG 801
Score = 71.3 bits (167), Expect = 5e-12
Identities = 63/255 (24%), Positives = 99/255 (38%), Gaps = 10/255 (3%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXX 166
P F + Q VK +F E+ + +V W+ + E + + D
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGT-VSL 224
G ++CTA N G+ SCS L V + P F L+ +G L
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
Query: 225 ECKVVGVPTPVLRWFKDSREIKAG----DVFALTANAED--PTSLGTYTCEAVNCMGRAY 278
+C V G P P + W + + I+ + + +D P GTYTC A N +G+
Sbjct: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
Query: 279 SSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPR 338
S+ V V + S S S PIF + L D V T++ Q+ P P
Sbjct: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP-PP 652
Query: 339 SVVWYNKEGKVEAGE 353
V+W + +++ E
Sbjct: 653 EVIWLHNGNEIQESE 667
Score = 68.1 bits (159), Expect = 4e-11
Identities = 70/253 (27%), Positives = 104/253 (41%), Gaps = 29/253 (11%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E+AG L + ART D+G Y+ ASNA G + L+V E E P+F L+D
Sbjct: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV--ERLAVMEVAPSFSSVLKD 522
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
V G + + ++TW N + + A + G
Sbjct: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHG 579
Query: 177 RWTCTAENVGGRASCSAHLNV-----------LVPKAYKRPE---FVEELRALLTEQGT- 221
+TC AEN G+ SCSA + V L+P A +P F++ L L G+
Sbjct: 580 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALTANAEDPTSLGTYTCEAVN 272
V++ +V G P P + W + EI+ + F +L P GTYTCEA N
Sbjct: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWN 699
Query: 273 CMGRAYSSSKVHV 285
G + + + V
Sbjct: 700 SAGEVRTQAVLTV 712
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/163 (29%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-PS--GEDPPTFL 111
+T +G ++TV G + Q S T R SA E+ PS GE PP F
Sbjct: 108 ATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFA 164
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+L + VK G RF +I + +VTW + L + RVS+
Sbjct: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
G +TC N G+AS SA L++ + R FV E +A
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR-SFVRETKA 266
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 1791 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1848
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 1849 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1907
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 39.1 bits (87), Expect = 0.023
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
P G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 1218 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 1253
Score = 38.7 bits (86), Expect = 0.031
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD------SREIKAGD---VFALTA 255
P+F +L ++ ++G + CK+ G P P + W K S + + + L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL----KPNSSGLSPEPPPIFT 311
+ + +G YTC VN G+A S+++ + G S S K +S + E + +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 312 RE 313
+E
Sbjct: 281 KE 282
Score = 38.3 bits (85), Expect = 0.040
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALT 254
P F+ R L ++G T E +V G P P + W ++ + I +G F+L
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
+A G YTCEA N G + ++ V G +++
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Score = 35.1 bits (77), Expect = 0.38
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 3/116 (2%)
Query: 85 AGSDTARVRLEV--SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWY 142
A S ++ L V S +S + P F+ ++L +K G +F + E +VTW+
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
Query: 143 RNERRLLEAERVSI-VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
RN + + R + F G++TC A N G + L V
Sbjct: 68 RNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 33.5 bits (73), Expect = 1.1
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ AR G YTL N GS A+V L V + P P R LT+
Sbjct: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/109 (17%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
E+E + + + G +T EN G +L V+
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 78.2 bits (184), Expect = 4e-14
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 22/243 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----------PS 103
ST EAG L + A D G YT A NA G + + V ++S PS
Sbjct: 559 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
P FL+ L DL V G++ V++ + +V W N + E+E + G+
Sbjct: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TV 222
G +TC A N G A L V P +P F+ + R++ G +V
Sbjct: 679 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
Query: 223 SLECKVVGVPTPVLRWFKDSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVN 272
+ C + G P P + W +D + ++ DVF L P G Y N
Sbjct: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Query: 273 CMG 275
+G
Sbjct: 799 RVG 801
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/255 (24%), Positives = 99/255 (38%), Gaps = 10/255 (3%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXX 166
P F + Q VK +F E+ + +V W+ + E + + +
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLC 473
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGT-VSL 224
G ++CTA N G+ SCS L V + P F L+ +G L
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
Query: 225 ECKVVGVPTPVLRWFKDSREIKAG----DVFALTANAED--PTSLGTYTCEAVNCMGRAY 278
+C V G P P + W + + I+ + + +D P GTYTC A N +G+
Sbjct: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
Query: 279 SSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPR 338
S+ V V + S S S PIF + L D V T++ Q+ P P
Sbjct: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP-PP 652
Query: 339 SVVWYNKEGKVEAGE 353
V+W + +++ E
Sbjct: 653 EVIWLHNGNEIQESE 667
Score = 67.7 bits (158), Expect = 6e-11
Identities = 70/253 (27%), Positives = 103/253 (40%), Gaps = 29/253 (11%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E AG L + ART D+G Y+ ASNA G + L+V E E P+F L+D
Sbjct: 465 ENAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV--ERLAVMEVAPSFSSVLKD 522
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
V G + + ++TW N + + A + G
Sbjct: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHG 579
Query: 177 RWTCTAENVGGRASCSAHLNV-----------LVPKAYKRPE---FVEELRALLTEQGT- 221
+TC AEN G+ SCSA + V L+P A +P F++ L L G+
Sbjct: 580 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALTANAEDPTSLGTYTCEAVN 272
V++ +V G P P + W + EI+ + F +L P GTYTCEA N
Sbjct: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
Query: 273 CMGRAYSSSKVHV 285
G + + + V
Sbjct: 700 SAGEVRTQAVLTV 712
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/163 (29%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-PS--GEDPPTFL 111
+T +G ++TV G + Q S T R SA E+ PS GE PP F
Sbjct: 108 ATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFA 164
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+L + VK G RF +I + +VTW + L + RVS+
Sbjct: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
G +TC N G+AS SA L++ + R FV E +A
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR-SFVRETKA 266
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 1791 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1848
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 1849 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1907
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 39.1 bits (87), Expect = 0.023
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
P G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 1218 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 1253
Score = 38.7 bits (86), Expect = 0.031
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD------SREIKAGD---VFALTA 255
P+F +L ++ ++G + CK+ G P P + W K S + + + L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL----KPNSSGLSPEPPPIFT 311
+ + +G YTC VN G+A S+++ + G S S K +S + E + +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 312 RE 313
+E
Sbjct: 281 KE 282
Score = 38.3 bits (85), Expect = 0.040
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALT 254
P F+ R L ++G T E +V G P P + W ++ + I +G F+L
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
+A G YTCEA N G + ++ V G +++
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Score = 35.1 bits (77), Expect = 0.38
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 3/116 (2%)
Query: 85 AGSDTARVRLEV--SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWY 142
A S ++ L V S +S + P F+ ++L +K G +F + E +VTW+
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
Query: 143 RNERRLLEAERVSI-VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
RN + + R + F G++TC A N G + L V
Sbjct: 68 RNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 33.5 bits (73), Expect = 1.1
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ AR G YTL N GS A+V L V + P P R LT+
Sbjct: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/109 (17%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
E+E + + + G +T EN G +L V+
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 78.2 bits (184), Expect = 4e-14
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 22/243 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----------PS 103
ST EAG L + A D G YT A NA G + + V ++S PS
Sbjct: 490 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
P FL+ L DL V G++ V++ + +V W N + E+E + G+
Sbjct: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TV 222
G +TC A N G A L V P +P F+ + R++ G +V
Sbjct: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 669
Query: 223 SLECKVVGVPTPVLRWFKDSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVN 272
+ C + G P P + W +D + ++ DVF L P G Y N
Sbjct: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
Query: 273 CMG 275
+G
Sbjct: 730 RVG 732
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/163 (29%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-PS--GEDPPTFL 111
+T +G ++TV G + Q S T R SA E+ PS GE PP F
Sbjct: 108 ATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFA 164
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+L + VK G RF +I + +VTW + L + RVS+
Sbjct: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
G +TC N G+AS SA L++ + R FV E +A
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR-SFVRETKA 266
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 1722 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1779
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 1780 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 48.8 bits (111), Expect = 3e-05
Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 8/155 (5%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAG----DVFALTANAED- 259
P F L+ +G L+C V G P P + W + + I+ + + +D
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA 504
Query: 260 -PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQY 318
P GTYTC A N +G+ S+ V V + S S S PIF + L D
Sbjct: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
Query: 319 VRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
V T++ Q+ P P V+W + +++ E
Sbjct: 565 VMDGSQVTMTVQVSGNP-PPEVIWLHNGNEIQESE 598
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 1735 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1794
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 1795 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1838
Score = 47.6 bits (108), Expect = 7e-05
Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 24/134 (17%)
Query: 176 GRWTCTAENVGGRASCSAHLNV-----------LVPKAYKRPE---FVEELRALLTEQGT 221
G +TC AEN G+ SCSA + V L+P A +P F++ L L G+
Sbjct: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
Query: 222 -VSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALTANAEDPTSLGTYTCEAV 271
V++ +V G P P + W + EI+ + F +L P GTYTCEA
Sbjct: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 629
Query: 272 NCMGRAYSSSKVHV 285
N G + + + V
Sbjct: 630 NSAGEVRTQAVLTV 643
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 1020 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1079
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 39.1 bits (87), Expect = 0.023
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
P G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 1149 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 1184
Score = 38.7 bits (86), Expect = 0.031
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD------SREIKAGD---VFALTA 255
P+F +L ++ ++G + CK+ G P P + W K S + + + L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL----KPNSSGLSPEPPPIFT 311
+ + +G YTC VN G+A S+++ + G S S K +S + E + +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 312 RE 313
+E
Sbjct: 281 KE 282
Score = 38.3 bits (85), Expect = 0.040
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALT 254
P F+ R L ++G T E +V G P P + W ++ + I +G F+L
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
+A G YTCEA N G + ++ V G +++
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Score = 35.1 bits (77), Expect = 0.38
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 3/116 (2%)
Query: 85 AGSDTARVRLEV--SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWY 142
A S ++ L V S +S + P F+ ++L +K G +F + E +VTW+
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
Query: 143 RNERRLLEAERVSI-VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
RN + + R + F G++TC A N G + L V
Sbjct: 68 RNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 33.5 bits (73), Expect = 1.1
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ AR G YTL N GS A+V L V + P P R LT+
Sbjct: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/109 (17%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
E+E + + + G +T EN G +L V+
Sbjct: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 78.2 bits (184), Expect = 4e-14
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 22/243 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----------PS 103
ST EAG L + A D G YT A NA G + + V ++S PS
Sbjct: 559 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
P FL+ L DL V G++ V++ + +V W N + E+E + G+
Sbjct: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TV 222
G +TC A N G A L V P +P F+ + R++ G +V
Sbjct: 679 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
Query: 223 SLECKVVGVPTPVLRWFKDSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVN 272
+ C + G P P + W +D + ++ DVF L P G Y N
Sbjct: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Query: 273 CMG 275
+G
Sbjct: 799 RVG 801
Score = 71.3 bits (167), Expect = 5e-12
Identities = 63/255 (24%), Positives = 99/255 (38%), Gaps = 10/255 (3%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXX 166
P F + Q VK +F E+ + +V W+ + E + + D
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGT-VSL 224
G ++CTA N G+ SCS L V + P F L+ +G L
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
Query: 225 ECKVVGVPTPVLRWFKDSREIKAG----DVFALTANAED--PTSLGTYTCEAVNCMGRAY 278
+C V G P P + W + + I+ + + +D P GTYTC A N +G+
Sbjct: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
Query: 279 SSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPR 338
S+ V V + S S S PIF + L D V T++ Q+ P P
Sbjct: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP-PP 652
Query: 339 SVVWYNKEGKVEAGE 353
V+W + +++ E
Sbjct: 653 EVIWLHNGNEIQESE 667
Score = 68.5 bits (160), Expect = 3e-11
Identities = 70/253 (27%), Positives = 104/253 (41%), Gaps = 29/253 (11%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E+AG L + ART D+G Y+ ASNA G + L+V E E P+F L+D
Sbjct: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV--ERLAVMEVAPSFSSVLKD 522
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
V G + + ++TW N + + A + G
Sbjct: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHG 579
Query: 177 RWTCTAENVGGRASCSAHLNV-----------LVPKAYKRPE---FVEELRALLTEQGT- 221
+TC AEN G+ SCSA + V L+P A +P F++ L L G+
Sbjct: 580 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALTANAEDPTSLGTYTCEAVN 272
V++ +V G P P + W + EI+ + F +L P GTYTCEA N
Sbjct: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
Query: 273 CMGRAYSSSKVHV 285
G + + + V
Sbjct: 700 SAGEVRTQAVLTV 712
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/163 (29%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-PS--GEDPPTFL 111
+T +G ++TV G + Q S T R SA E+ PS GE PP F
Sbjct: 108 ATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFA 164
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+L + VK G RF +I + +VTW + L + RVS+
Sbjct: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
G +TC N G+AS SA L++ + R FV E +A
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR-SFVRETKA 266
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 1791 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1848
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 1849 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1907
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 39.1 bits (87), Expect = 0.023
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
P G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 1218 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 1253
Score = 38.7 bits (86), Expect = 0.031
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD------SREIKAGD---VFALTA 255
P+F +L ++ ++G + CK+ G P P + W K S + + + L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL----KPNSSGLSPEPPPIFT 311
+ + +G YTC VN G+A S+++ + G S S K +S + E + +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 312 RE 313
+E
Sbjct: 281 KE 282
Score = 38.3 bits (85), Expect = 0.040
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALT 254
P F+ R L ++G T E +V G P P + W ++ + I +G F+L
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
+A G YTCEA N G + ++ V G +++
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Score = 35.1 bits (77), Expect = 0.38
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 3/116 (2%)
Query: 85 AGSDTARVRLEV--SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWY 142
A S ++ L V S +S + P F+ ++L +K G +F + E +VTW+
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
Query: 143 RNERRLLEAERVSI-VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
RN + + R + F G++TC A N G + L V
Sbjct: 68 RNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 33.5 bits (73), Expect = 1.1
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ AR G YTL N GS A+V L V + P P R LT+
Sbjct: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/109 (17%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
E+E + + + G +T EN G +L V+
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 78.2 bits (184), Expect = 4e-14
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 22/243 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----------PS 103
ST EAG L + A D G YT A NA G + + V ++S PS
Sbjct: 490 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
P FL+ L DL V G++ V++ + +V W N + E+E + G+
Sbjct: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TV 222
G +TC A N G A L V P +P F+ + R++ G +V
Sbjct: 610 SLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 669
Query: 223 SLECKVVGVPTPVLRWFKDSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVN 272
+ C + G P P + W +D + ++ DVF L P G Y N
Sbjct: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
Query: 273 CMG 275
+G
Sbjct: 730 RVG 732
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/163 (29%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-PS--GEDPPTFL 111
+T +G ++TV G + Q S T R SA E+ PS GE PP F
Sbjct: 108 ATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFA 164
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+L + VK G RF +I + +VTW + L + RVS+
Sbjct: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
G +TC N G+AS SA L++ + R FV E +A
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR-SFVRETKA 266
Score = 48.8 bits (111), Expect = 3e-05
Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 8/155 (5%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAG----DVFALTANAED- 259
P F L+ +G L+C V G P P + W + + I+ + + +D
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA 504
Query: 260 -PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQY 318
P GTYTC A N +G+ S+ V V + S S S PIF + L D
Sbjct: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
Query: 319 VRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
V T++ Q+ P P V+W + +++ E
Sbjct: 565 VMDGSQVTMTVQVSGNP-PPEVIWLHNGNEIQESE 598
Score = 48.0 bits (109), Expect = 5e-05
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 12/97 (12%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 1683 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1742
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVV 286
SL YTC+AVN +G A +++ H+V
Sbjct: 1743 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE-HIV 1778
Score = 47.6 bits (108), Expect = 7e-05
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 1670 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1727
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSA 193
+ E+ I D C ++TC A N G A+C+A
Sbjct: 1728 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1774
Score = 47.2 bits (107), Expect = 9e-05
Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 24/134 (17%)
Query: 176 GRWTCTAENVGGRASCSAHLNV-----------LVPKAYKRPE---FVEELRALLTEQGT 221
G +TC AEN G+ SCSA + V L+P A +P F++ L L G+
Sbjct: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
Query: 222 -VSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALTANAEDPTSLGTYTCEAV 271
V++ +V G P P + W + EI+ + F +L P GTYTCEA
Sbjct: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAW 629
Query: 272 NCMGRAYSSSKVHV 285
N G + + + V
Sbjct: 630 NSAGEVRTQAVLTV 643
Score = 45.2 bits (102), Expect = 4e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 1020 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1079
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 1080 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 38.7 bits (86), Expect = 0.031
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD------SREIKAGD---VFALTA 255
P+F +L ++ ++G + CK+ G P P + W K S + + + L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL----KPNSSGLSPEPPPIFT 311
+ + +G YTC VN G+A S+++ + G S S K +S + E + +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 312 RE 313
+E
Sbjct: 281 KE 282
Score = 38.3 bits (85), Expect = 0.040
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALT 254
P F+ R L ++G T E +V G P P + W ++ + I +G F+L
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
+A G YTCEA N G + ++ V G +++
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Score = 35.1 bits (77), Expect = 0.38
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 3/116 (2%)
Query: 85 AGSDTARVRLEV--SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWY 142
A S ++ L V S +S + P F+ ++L +K G +F + E +VTW+
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
Query: 143 RNERRLLEAERVSI-VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
RN + + R + F G++TC A N G + L V
Sbjct: 68 RNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 35.1 bits (77), Expect = 0.38
Identities = 36/160 (22%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 1089 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 1149 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 1184
Score = 34.7 bits (76), Expect = 0.50
Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Query: 50 DDRFVSTEEA-GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
D + E + G +LT+ AR G YTL N GS A+V L V + P P
Sbjct: 1211 DSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1270
Query: 109 TFLRRLQDLTV 119
R LT+
Sbjct: 1271 ASDIRSSSLTL 1281
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/109 (16%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
++E + + + G +T EN G +L V+
Sbjct: 1211 DSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 78.2 bits (184), Expect = 4e-14
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 22/243 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----------PS 103
ST EAG L + A D G YT A NA G + + V ++S PS
Sbjct: 559 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
P FL+ L DL V G++ V++ + +V W N + E+E + G+
Sbjct: 619 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TV 222
G +TC A N G A L V P +P F+ + R++ G +V
Sbjct: 679 SLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
Query: 223 SLECKVVGVPTPVLRWFKDSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVN 272
+ C + G P P + W +D + ++ DVF L P G Y N
Sbjct: 739 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Query: 273 CMG 275
+G
Sbjct: 799 RVG 801
Score = 71.3 bits (167), Expect = 5e-12
Identities = 63/255 (24%), Positives = 99/255 (38%), Gaps = 10/255 (3%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXX 166
P F + Q VK +F E+ + +V W+ + E + + D
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGT-VSL 224
G ++CTA N G+ SCS L V + P F L+ +G L
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
Query: 225 ECKVVGVPTPVLRWFKDSREIKAG----DVFALTANAED--PTSLGTYTCEAVNCMGRAY 278
+C V G P P + W + + I+ + + +D P GTYTC A N +G+
Sbjct: 534 QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
Query: 279 SSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPR 338
S+ V V + S S S PIF + L D V T++ Q+ P P
Sbjct: 594 CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP-PP 652
Query: 339 SVVWYNKEGKVEAGE 353
V+W + +++ E
Sbjct: 653 EVIWLHNGNEIQESE 667
Score = 68.1 bits (159), Expect = 4e-11
Identities = 70/253 (27%), Positives = 104/253 (41%), Gaps = 29/253 (11%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E+AG L + ART D+G Y+ ASNA G + L+V E E P+F L+D
Sbjct: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV--ERLAVMEVAPSFSSVLKD 522
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
V G + + ++TW N + + A + G
Sbjct: 523 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHG 579
Query: 177 RWTCTAENVGGRASCSAHLNV-----------LVPKAYKRPE---FVEELRALLTEQGT- 221
+TC AEN G+ SCSA + V L+P A +P F++ L L G+
Sbjct: 580 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALTANAEDPTSLGTYTCEAVN 272
V++ +V G P P + W + EI+ + F +L P GTYTCEA N
Sbjct: 640 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWN 699
Query: 273 CMGRAYSSSKVHV 285
G + + + V
Sbjct: 700 SAGEVRTQAVLTV 712
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/163 (29%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-PS--GEDPPTFL 111
+T +G ++TV G + Q S T R SA E+ PS GE PP F
Sbjct: 108 ATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFA 164
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+L + VK G RF +I + +VTW + L + RVS+
Sbjct: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
G +TC N G+AS SA L++ + R FV E +A
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR-SFVRETKA 266
Score = 48.0 bits (109), Expect = 5e-05
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 12/97 (12%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 1752 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1811
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVV 286
SL YTC+AVN +G A +++ H+V
Sbjct: 1812 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE-HIV 1847
Score = 47.6 bits (108), Expect = 7e-05
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 1739 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1796
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSA 193
+ E+ I D C ++TC A N G A+C+A
Sbjct: 1797 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1843
Score = 45.2 bits (102), Expect = 4e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 1149 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 38.7 bits (86), Expect = 0.031
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD------SREIKAGD---VFALTA 255
P+F +L ++ ++G + CK+ G P P + W K S + + + L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL----KPNSSGLSPEPPPIFT 311
+ + +G YTC VN G+A S+++ + G S S K +S + E + +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 312 RE 313
+E
Sbjct: 281 KE 282
Score = 38.3 bits (85), Expect = 0.040
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALT 254
P F+ R L ++G T E +V G P P + W ++ + I +G F+L
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
+A G YTCEA N G + ++ V G +++
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Score = 35.1 bits (77), Expect = 0.38
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 3/116 (2%)
Query: 85 AGSDTARVRLEV--SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWY 142
A S ++ L V S +S + P F+ ++L +K G +F + E +VTW+
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
Query: 143 RNERRLLEAERVSI-VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
RN + + R + F G++TC A N G + L V
Sbjct: 68 RNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 35.1 bits (77), Expect = 0.38
Identities = 36/160 (22%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 1158 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 1218 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 1253
Score = 34.7 bits (76), Expect = 0.50
Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Query: 50 DDRFVSTEEA-GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
D + E + G +LT+ AR G YTL N GS A+V L V + P P
Sbjct: 1280 DSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339
Query: 109 TFLRRLQDLTV 119
R LT+
Sbjct: 1340 ASDIRSSSLTL 1350
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/109 (16%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
++E + + + G +T EN G +L V+
Sbjct: 1280 DSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 78.2 bits (184), Expect = 4e-14
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 22/243 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----------PS 103
ST EAG L + A D G YT A NA G + + V ++S PS
Sbjct: 490 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
P FL+ L DL V G++ V++ + +V W N + E+E + G+
Sbjct: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TV 222
G +TC A N G A L V P +P F+ + R++ G +V
Sbjct: 610 SLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 669
Query: 223 SLECKVVGVPTPVLRWFKDSRE----------IKAGDVFALTANAEDPTSLGTYTCEAVN 272
+ C + G P P + W +D + ++ DVF L P G Y N
Sbjct: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
Query: 273 CMG 275
+G
Sbjct: 730 RVG 732
Score = 55.6 bits (128), Expect = 2e-07
Identities = 48/163 (29%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-PS--GEDPPTFL 111
+T +G ++TV G + Q S T R SA E+ PS GE PP F
Sbjct: 108 ATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFA 164
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
+L + VK G RF +I + +VTW + L + RVS+
Sbjct: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
G +TC N G+AS SA L++ + R FV E +A
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR-SFVRETKA 266
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 1722 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1779
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 1780 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 48.8 bits (111), Expect = 3e-05
Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 8/155 (5%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAG----DVFALTANAED- 259
P F L+ +G L+C V G P P + W + + I+ + + +D
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA 504
Query: 260 -PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQY 318
P GTYTC A N +G+ S+ V V + S S S PIF + L D
Sbjct: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
Query: 319 VRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
V T++ Q+ P P V+W + +++ E
Sbjct: 565 VMDGSQVTMTVQVSGNP-PPEVIWLHNGNEIQESE 598
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 1735 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1794
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 1795 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1838
Score = 47.2 bits (107), Expect = 9e-05
Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 24/134 (17%)
Query: 176 GRWTCTAENVGGRASCSAHLNV-----------LVPKAYKRPE---FVEELRALLTEQGT 221
G +TC AEN G+ SCSA + V L+P A +P F++ L L G+
Sbjct: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
Query: 222 -VSLECKVVGVPTPVLRWFKDSREIKAGDVF---------ALTANAEDPTSLGTYTCEAV 271
V++ +V G P P + W + EI+ + F +L P GTYTCEA
Sbjct: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAW 629
Query: 272 NCMGRAYSSSKVHV 285
N G + + + V
Sbjct: 630 NSAGEVRTQAVLTV 643
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 1020 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1079
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 39.1 bits (87), Expect = 0.023
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
P G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 1149 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 1184
Score = 38.7 bits (86), Expect = 0.031
Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD------SREIKAGD---VFALTA 255
P+F +L ++ ++G + CK+ G P P + W K S + + + L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL----KPNSSGLSPEPPPIFT 311
+ + +G YTC VN G+A S+++ + G S S K +S + E + +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 312 RE 313
+E
Sbjct: 281 KE 282
Score = 38.3 bits (85), Expect = 0.040
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALT 254
P F+ R L ++G T E +V G P P + W ++ + I +G F+L
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
+A G YTCEA N G + ++ V G +++
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Score = 35.1 bits (77), Expect = 0.38
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 3/116 (2%)
Query: 85 AGSDTARVRLEV--SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWY 142
A S ++ L V S +S + P F+ ++L +K G +F + E +VTW+
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
Query: 143 RNERRLLEAERVSI-VRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
RN + + R + F G++TC A N G + L V
Sbjct: 68 RNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 33.5 bits (73), Expect = 1.1
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ AR G YTL N GS A+V L V + P P R LT+
Sbjct: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/109 (17%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
E+E + + + G +T EN G +L V+
Sbjct: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 75.8 bits (178), Expect = 2e-13
Identities = 71/238 (29%), Positives = 98/238 (41%), Gaps = 21/238 (8%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
VST+ G +L ++ A D G Y A N+AGS + RL V PP
Sbjct: 889 VSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQV--------PPVIENG 940
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXX 172
L DL+ G+ + S E +TW ++ + + AE + +I G
Sbjct: 941 LPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDA 1000
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVP 232
G +TCTAEN GRA HL +LV + LR L ++ + L C G P
Sbjct: 1001 ---GTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLR--LGDR--LWLRCAARGSP 1053
Query: 233 TPVLRWFKDSREIKAG-----DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
TP + W + R + G L A GTY C A N +GR + S VHV
Sbjct: 1054 TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHV 1111
Score = 58.0 bits (134), Expect = 5e-08
Identities = 64/243 (26%), Positives = 91/243 (37%), Gaps = 24/243 (9%)
Query: 43 SRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
S+AGA L R + L + A G YT A N+AG V L V A SP
Sbjct: 788 SKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQA--SP 845
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
+ P+ +R + + V + E +TW + + ++ G
Sbjct: 846 VVKPLPSVVRAVAEEEVLLP------CEASGIPRPTITWQKEGLNVATGVSTQVLPGGQL 899
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT- 221
G + C A+N G A L V VP P L L T +G+
Sbjct: 900 ---RIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP-----PVIENGLPDLSTTEGSH 951
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGD-VFALTANAE------DPTSLGTYTCEAVNCM 274
L CK G P P + W KD + + + F + + E + GTYTC A N +
Sbjct: 952 AFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAV 1011
Query: 275 GRA 277
GRA
Sbjct: 1012 GRA 1014
Score = 57.2 bits (132), Expect = 8e-08
Identities = 76/299 (25%), Positives = 109/299 (36%), Gaps = 45/299 (15%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L V D G YT A NA G RV L + P F D ++++G
Sbjct: 990 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVL--------PVFTTLPGDRSLRLGD 1041
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R S ++ W N+R + E VS GS G + C AE
Sbjct: 1042 RLWLRCAARGSPTPRIGWTVNDRPVTEG--VSEQDGGSTL--QRAAVSREDSGTYVCWAE 1097
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQ--GTVSLECKVVGVPTPVLRWFKD 241
N GR + ++V + P E + L E G++ L+C V G P P + W KD
Sbjct: 1098 NRVGRTQAVSFVHVK-----EAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKD 1152
Query: 242 SREIKAGDV------FALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ + +LT + + G Y C A N MG A KV +
Sbjct: 1153 GLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA---KKVVI---------- 1199
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
L + P+F E +D VR + L CQ P P ++ W + A R
Sbjct: 1200 ------LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTP-TIEWLQAGQPLRASRR 1251
Score = 51.6 bits (118), Expect = 4e-06
Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 14/179 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L V + D G+YT A + AG+ R+ V A + G P F+ L + +
Sbjct: 460 LRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLE- 518
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + K+TW+R+ L E G F G ++CTA
Sbjct: 519 -----CSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFL--QLQALSTADSGDYSCTAR 571
Query: 184 NVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
N G S + + + VP P V ++ T L C+ GVP P++ W KD
Sbjct: 572 NAAGSTSVAFRVEIHTVPTIRSGPPAVN-----VSVNQTALLPCQADGVPAPLVSWRKD 625
Score = 51.2 bits (117), Expect = 5e-06
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G ++C NV G A + L V VP ++ P+ E + + V L C V GVP P
Sbjct: 12 GLYSCKVSNVAGEAVRTFTLTVQVPPTFENPK--TETVSQVAGSPLV-LTCDVSGVPAPT 68
Query: 236 LRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ W KD +++ V + + P GTYTC A N A V V+
Sbjct: 69 VTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL 126
Score = 50.0 bits (114), Expect = 1e-05
Identities = 59/263 (22%), Positives = 94/263 (35%), Gaps = 19/263 (7%)
Query: 30 WRHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDT 89
W R S G + +S G L + GD+G Y+ A + AG
Sbjct: 335 WNSRARPGAFPCLSCRGMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGE-- 392
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
AR +++ E P ED + +L++ G L + + + +TW+++ + L
Sbjct: 393 ARRHFQLTVMEPPHIEDS----GQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT 448
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFV 209
E S + G +TC AE+ G S + V P P
Sbjct: 449 RLENNS----RATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGP 504
Query: 210 EELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIK--AGDVFA-----LTANAEDPTS 262
+ L G + LEC V P P + W +D ++ A F L A
Sbjct: 505 RFVVGL--APGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTAD 562
Query: 263 LGTYTCEAVNCMGRAYSSSKVHV 285
G Y+C A N G + +V +
Sbjct: 563 SGDYSCTARNAAGSTSVAFRVEI 585
Score = 48.0 bits (109), Expect = 5e-05
Identities = 46/179 (25%), Positives = 70/179 (39%), Gaps = 13/179 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ D G+Y+ + SN AG L V P+ E+P T + ++ G+
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP--PTFENPKT-----ETVSQVAGS 53
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERV-SIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
++ VTW + +R +E+ V +V G G +TC A
Sbjct: 54 PLVLTCDVSGVPAPTVTWLK-DRMPVESSAVHGVVSRGGRL--QLSRLQPAQAGTYTCVA 110
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
EN A + VLV + E L E V L+C+ G P P + W KD
Sbjct: 111 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVL--EGQEVRLDCEADGQPPPDVAWLKD 167
Score = 46.4 bits (105), Expect = 2e-04
Identities = 60/254 (23%), Positives = 95/254 (37%), Gaps = 25/254 (9%)
Query: 44 RAGASLDDRFVS---TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
R G +++DR V+ +E+ GG L + D+G Y A N G A + V
Sbjct: 1056 RIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 1115
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
GE L VG + + + W ++ L + +++G
Sbjct: 1116 VLQGE-------AFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG 1168
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG 220
S GR+ C AEN G A V++ P F E + + G
Sbjct: 1169 SL---TIHRTERDDAGRYQCLAENEMGVAK-----KVVILVLQSAPVFQVEPQDMTVRSG 1220
Query: 221 T-VSLECKVVGVPTPVLRW------FKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNC 273
V+L C+ G PTP + W + SR ++ +L + GTY C A N
Sbjct: 1221 DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNL 1280
Query: 274 MGRAYSSSKVHVVG 287
+G A + + + V G
Sbjct: 1281 LGSATARAFLVVRG 1294
Score = 45.2 bits (102), Expect = 4e-04
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC+A N G A L V K V +RA+ E+ V L C+ G+P P
Sbjct: 820 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSV--VRAVAEEE--VLLPCEASGIPRPT 875
Query: 236 LRWFKDSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+ W K+ + G + + P G Y C A N G A +++ V
Sbjct: 876 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 931
Score = 36.3 bits (80), Expect = 0.16
Identities = 31/110 (28%), Positives = 45/110 (40%), Gaps = 10/110 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTP 234
G +TC A N G + +NVLVP K + + L++ G V++ C V G P
Sbjct: 199 GAYTCVAHNPAGEDARLHTVNVLVPPTIK--QGADGSGTLVSRPGELVTMVCPVRGSPPI 256
Query: 235 VLRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA 277
+ W KD R + G L + G +TC A + G A
Sbjct: 257 HVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVA 306
Score = 35.9 bits (79), Expect = 0.22
Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 8/135 (5%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G ++C A + G A L V+ P + EL LT + L C G P P
Sbjct: 380 GTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELS--LTPGAPMELLCDAQGTPQPN 437
Query: 236 LRWFKDSR-----EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
+ W KD + E + L G YTC A + G S +V V +
Sbjct: 438 ITWHKDGQALTRLENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPN 497
Query: 291 REGSLKPN-SSGLSP 304
G P GL+P
Sbjct: 498 IVGPRGPRFVVGLAP 512
Score = 33.9 bits (74), Expect = 0.87
Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 11/109 (10%)
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVL 236
++ C N G A + V VP ++ +T V L C G+P P +
Sbjct: 730 QFECVVSNEVGEAHRLYQVTVHVPPTIAD----DQTDFTVTMMAPVVLTCHSTGIPAPTV 785
Query: 237 RWFKDSREIKA-GDVF------ALTANAEDPTSLGTYTCEAVNCMGRAY 278
W K ++ A G + AL P G YTC A N G A+
Sbjct: 786 SWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH 834
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 73.3 bits (172), Expect = 1e-12
Identities = 78/305 (25%), Positives = 129/305 (42%), Gaps = 20/305 (6%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G+ LDD+ GG +L ++ R D G Y +N G + V E++ E PS
Sbjct: 169 GSPLDDKDERITIRGG-KLMITYTRKSDAGKYVCVGTNMVGERESEVA-ELTVLERPS-- 224
Query: 106 DPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
F++R +L V V F E V W +++ L ++ R I D +
Sbjct: 225 ----FVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTL--- 276
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSL 224
G +TC AEN+ G+A SA L V V + P FV + R + G TV+
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPPHFVVKPRDQVVALGRTVTF 334
Query: 225 ECKVVGVPTPVLRWFKD-SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSK 282
+C+ G P P + W ++ S+ + +++ + G T V Y
Sbjct: 335 QCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 394
Query: 283 VHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
++V G + L+ + ++ PPP+ + +Q V + F LSC P P +++W
Sbjct: 395 LNVAGSIITKAYLEV-TDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP-TILW 452
Query: 343 YNKEG 347
K+G
Sbjct: 453 -RKDG 456
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/261 (24%), Positives = 89/261 (34%), Gaps = 25/261 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + GD G YT A N G A L V G +PP F+ + +D V +G
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV-----GSEPPHFVVKPRDQVVALGR 330
Query: 124 RTRFLVEIISSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXX 175
F E + + + W R + LL + R S+ + G
Sbjct: 331 TVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDL---TITNVQRSDV 387
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVPT 233
G + C NV G A+L V A + P + + + + GT L C G P
Sbjct: 388 GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV 447
Query: 234 PVLRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
P + W KD IK + L G YTC A G A S+ + V
Sbjct: 448 PTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
Query: 287 GRASREGSLKPNSSGLSPEPP 307
+P L P P
Sbjct: 508 EFGVPVQPPRPTDPNLIPSAP 528
Score = 33.9 bits (74), Expect = 0.87
Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIK 246
P VE L+ +G +L CK G PTP + W+K ++
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVE 70
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 73.3 bits (172), Expect = 1e-12
Identities = 78/305 (25%), Positives = 129/305 (42%), Gaps = 20/305 (6%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G+ LDD+ GG +L ++ R D G Y +N G + V E++ E PS
Sbjct: 169 GSPLDDKDERITIRGG-KLMITYTRKSDAGKYVCVGTNMVGERESEVA-ELTVLERPS-- 224
Query: 106 DPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
F++R +L V V F E V W +++ L ++ R I D +
Sbjct: 225 ----FVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTL--- 276
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSL 224
G +TC AEN+ G+A SA L V V + P FV + R + G TV+
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPPHFVVKPRDQVVALGRTVTF 334
Query: 225 ECKVVGVPTPVLRWFKD-SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSK 282
+C+ G P P + W ++ S+ + +++ + G T V Y
Sbjct: 335 QCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 394
Query: 283 VHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
++V G + L+ + ++ PPP+ + +Q V + F LSC P P +++W
Sbjct: 395 LNVAGSIITKAYLEV-TDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP-TILW 452
Query: 343 YNKEG 347
K+G
Sbjct: 453 -RKDG 456
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/261 (24%), Positives = 89/261 (34%), Gaps = 25/261 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + GD G YT A N G A L V G +PP F+ + +D V +G
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV-----GSEPPHFVVKPRDQVVALGR 330
Query: 124 RTRFLVEIISSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXX 175
F E + + + W R + LL + R S+ + G
Sbjct: 331 TVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDL---TITNVQRSDV 387
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVPT 233
G + C NV G A+L V A + P + + + + GT L C G P
Sbjct: 388 GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV 447
Query: 234 PVLRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
P + W KD IK + L G YTC A G A S+ + V
Sbjct: 448 PTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
Query: 287 GRASREGSLKPNSSGLSPEPP 307
+P L P P
Sbjct: 508 EFGVPVQPPRPTDPNLIPSAP 528
Score = 33.9 bits (74), Expect = 0.87
Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIK 246
P VE L+ +G +L CK G PTP + W+K ++
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVE 70
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 73.3 bits (172), Expect = 1e-12
Identities = 78/305 (25%), Positives = 129/305 (42%), Gaps = 20/305 (6%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G+ LDD+ GG +L ++ R D G Y +N G + V E++ E PS
Sbjct: 169 GSPLDDKDERITIRGG-KLMITYTRKSDAGKYVCVGTNMVGERESEVA-ELTVLERPS-- 224
Query: 106 DPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
F++R +L V V F E V W +++ L ++ R I D +
Sbjct: 225 ----FVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTL--- 276
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSL 224
G +TC AEN+ G+A SA L V V + P FV + R + G TV+
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPPHFVVKPRDQVVALGRTVTF 334
Query: 225 ECKVVGVPTPVLRWFKD-SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSK 282
+C+ G P P + W ++ S+ + +++ + G T V Y
Sbjct: 335 QCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 394
Query: 283 VHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
++V G + L+ + ++ PPP+ + +Q V + F LSC P P +++W
Sbjct: 395 LNVAGSIITKAYLEV-TDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP-TILW 452
Query: 343 YNKEG 347
K+G
Sbjct: 453 -RKDG 456
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/261 (24%), Positives = 89/261 (34%), Gaps = 25/261 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + GD G YT A N G A L V G +PP F+ + +D V +G
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV-----GSEPPHFVVKPRDQVVALGR 330
Query: 124 RTRFLVEIISSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXX 175
F E + + + W R + LL + R S+ + G
Sbjct: 331 TVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDL---TITNVQRSDV 387
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVPT 233
G + C NV G A+L V A + P + + + + GT L C G P
Sbjct: 388 GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV 447
Query: 234 PVLRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
P + W KD IK + L G YTC A G A S+ + V
Sbjct: 448 PTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
Query: 287 GRASREGSLKPNSSGLSPEPP 307
+P L P P
Sbjct: 508 EFGVPVQPPRPTDPNLIPSAP 528
Score = 33.9 bits (74), Expect = 0.87
Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIK 246
P VE L+ +G +L CK G PTP + W+K ++
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVE 70
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/305 (25%), Positives = 128/305 (41%), Gaps = 23/305 (7%)
Query: 46 GASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGE 105
G+ LDD+ GG +L ++ R D G Y +N G + V E++ E PS
Sbjct: 208 GSPLDDKDERITIRGG-KLMITYTRKSDAGKYVCVGTNMVGERESEVA-ELTVLERPS-- 263
Query: 106 DPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX 165
F++R +L V V F E V W +++ L ++ R I D +
Sbjct: 264 ----FVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTL--- 315
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSL 224
G +TC AEN+ G+A SA L V P P FV + R + G TV+
Sbjct: 316 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP-----PHFVVKPRDQVVALGRTVTF 370
Query: 225 ECKVVGVPTPVLRWFKD-SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSK 282
+C+ G P P + W ++ S+ + +++ + G T V Y
Sbjct: 371 QCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 430
Query: 283 VHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
++V G + L+ + ++ PPP+ + +Q V + F LSC P P +++W
Sbjct: 431 LNVAGSIITKAYLEV-TDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP-TILW 488
Query: 343 YNKEG 347
K+G
Sbjct: 489 -RKDG 492
Score = 55.6 bits (128), Expect = 2e-07
Identities = 63/261 (24%), Positives = 89/261 (34%), Gaps = 28/261 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + GD G YT A N G A L V ++PP F+ + +D V +G
Sbjct: 315 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTV--------QEPPHFVVKPRDQVVALGR 366
Query: 124 RTRFLVEIISSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXX 175
F E + + + W R + LL + R S+ + G
Sbjct: 367 TVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDL---TITNVQRSDV 423
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVPT 233
G + C NV G A+L V A + P + + + + GT L C G P
Sbjct: 424 GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV 483
Query: 234 PVLRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
P + W KD IK + L G YTC A G A S+ + V
Sbjct: 484 PTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 543
Query: 287 GRASREGSLKPNSSGLSPEPP 307
+P L P P
Sbjct: 544 EFGVPVQPPRPTDPNLIPSAP 564
Score = 33.9 bits (74), Expect = 0.87
Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIK 246
P VE L+ +G +L CK G PTP + W+K ++
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVE 109
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 71.3 bits (167), Expect = 5e-12
Identities = 52/215 (24%), Positives = 90/215 (41%), Gaps = 15/215 (6%)
Query: 100 ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD 159
+ P P FL R + V VG +I+ + +V+W ++++ + R + +D
Sbjct: 2 DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK--AYKRPEFVEELRALLT 217
G + G++ C A N G A + L V A + P F+ ++
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121
Query: 218 EQGT-VSLECKVVGVPTPVLRWFKDSREI-----------KAGDVFALTANAEDPTSLGT 265
+G+ + C+V G P P + W KD R + + G+ AL A P GT
Sbjct: 122 REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181
Query: 266 YTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
Y A N +G A S++ VV + + + +P +S
Sbjct: 182 YEVRAENPLGAA-SAAAALVVDSDAADTASRPGTS 215
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 6127
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 6188 LGSARASAELRI 6199
Score = 66.1 bits (154), Expect = 2e-10
Identities = 91/344 (26%), Positives = 131/344 (38%), Gaps = 62/344 (18%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
RF ++ RLT+ GD+G Y +A NA G A V L+V A E+ E P FL
Sbjct: 55 RFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-EAACAEQAPHFL 113
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXX 169
R + V+ G+ F + S V+W ++ RRL E + RV + G
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNV-----------------LVPKAYKRPEFVEEL 212
G + AEN G AS +A L V L+ +R E +
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAE 233
Query: 213 RALLTEQGTVSLECKV------------VGVPTPVLRWFKDSREIKAGDVFALTANAED- 259
A + T + C V G P P W KD + + G + +A++
Sbjct: 234 GAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQEN 293
Query: 260 ---------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
+ G YTC A N +G+ YSS V VV R EP F
Sbjct: 294 FVLKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVR----------------EPAVPF 335
Query: 311 TRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ L+D VR E T C+ VP W+ +E ++ A +
Sbjct: 336 KKRLQDLEVREKESATFLCE--VPQPSTEAAWFKEETRLWASAK 377
Score = 54.4 bits (125), Expect = 6e-07
Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
+RF+ + RL +T D G Y+ + G D+ RL VS + ++
Sbjct: 842 ERFLQEDVGTRHRLVAATVTRQDEGTYSCRV----GEDSVDFRLRVSEPKVVFAKEQLA- 896
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
R+LQ + G E+ + + +VTWY++ ++L + +V + G
Sbjct: 897 RRKLQ---AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQA 952
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVG 230
G ++C A GG+ S HL+V PK + V + +L C+V
Sbjct: 953 GQADAGEYSCEA---GGQR-LSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQ 1008
Query: 231 VPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
T V+ W+KD +++ + G L T G Y+CEA
Sbjct: 1009 AQTEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056
Score = 53.2 bits (122), Expect = 1e-06
Identities = 57/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 2792 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 2850
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 2851 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 2908
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 2909 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 2961
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
G LT +A + TYTC+ +G+A S +++ V GR
Sbjct: 2962 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGR 3003
Score = 52.0 bits (119), Expect = 3e-06
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)
Query: 206 PEFVEELRALLTEQGT--VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTAN------- 256
P+ VEELR L GT + KV G P P L WFKD + + A +T
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 257 --AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTREL 314
+ G Y N MG AYSS+++ V R E KP S PP
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLV--RGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 315 EDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ V+ T S ++ P P +V W +E +
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVP-TVHWLREEAE 5410
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 6000 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 6058
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 6059 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 6110
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ +V E +C I P+P+ + WY + G +
Sbjct: 6111 VNKVRASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 6153
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 16/194 (8%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V D G Y+ +A G +L ++ ++ ++ ++ + G
Sbjct: 1222 RLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVH----NEVRTEAG 1273
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V I G G +TC A
Sbjct: 1274 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV-SLECKVVGVPTPVLRWFKD 241
GG+ S HL+V PKA E + R + E G + +L C+V T V W+KD
Sbjct: 1333 ---GGQ-RLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQAQTEV-TWYKD 1386
Query: 242 SREIKAGDVFALTA 255
+++ + + A
Sbjct: 1387 GKKLSSSSKVRMEA 1400
Score = 49.6 bits (113), Expect = 2e-05
Identities = 61/256 (23%), Positives = 100/256 (39%), Gaps = 19/256 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA----EESPSGED-----PPTFLRRL 114
L + + D+G Y SNA G+ + RL V EE P+ + PP L R
Sbjct: 5318 LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 115 QDLTVKVGTRTRFLVEIISSTECKVTWYRNE--RRLL----EAERVSIVRDGSFFCXXXX 168
VK G+ F V++ V W R E R +L + ++
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLL 5437
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECK 227
G +TC A N G+A CSA L+V +PK ++ + E L + + T ++ +
Sbjct: 5438 DVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQ 5497
Query: 228 VVGVPT-PVLRWFKDSREIKAGDVFALTANAEDPTS--LGTYTCEAVNCMGRAYSSSKVH 284
+ + L + + A + + AE T L T + + + +K+
Sbjct: 5498 GLETASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQ 5557
Query: 285 VVGRASREGSLKPNSS 300
V G S E S P++S
Sbjct: 5558 VPGGDSDEDSKTPSAS 5573
Score = 48.4 bits (110), Expect = 4e-05
Identities = 49/205 (23%), Positives = 75/205 (36%), Gaps = 17/205 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+YT ASN G + V + V P F +RLQDL V+
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVP-------FKKRLQDLEVREKE 348
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
FL E + + W++ E RL + + I +G+ + C
Sbjct: 349 SATFLCE-VPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETP 407
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G R A L V K P R G ++ C + VP + W ++
Sbjct: 408 E-GSRT--VAELAVQGNLLRKLP------RKTAVRVGDTAMFCVELAVPVGPVHWLRNQE 458
Query: 244 EIKAGDVFALTANAEDPTSLGTYTC 268
E+ AG A++A T + C
Sbjct: 459 EVVAGGRVAISAEGTRHTLTISQCC 483
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED----- 259
P F+ EL+ + G VS +C V G P P +RWFKD + ++ D + + + +
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 260 -----PTSLGTYTCEAVNCMGRAYSSSKVHV 285
P +G Y C A N MG + + +++ V
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 46.8 bits (106), Expect = 1e-04
Identities = 60/273 (21%), Positives = 105/273 (38%), Gaps = 26/273 (9%)
Query: 68 TARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG--EDPPTFLRRLQDLTVKVGTRT 125
TA GDT T+ + S R+ ++ P E F R L+ + ++G
Sbjct: 1767 TASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTV 1826
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
E+ S +V W +L +R +V +G G + C + +
Sbjct: 1827 TLACEL-SPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRD- 1884
Query: 186 GGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSRE 244
SA L V VP+ K F+ L ++ E+G + +C VV + WF+D
Sbjct: 1885 ---DHTSAQLTVSVPRVVK---FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGAL 1937
Query: 245 IKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSP 304
++ + FA++ + +++ + + V G AS +L+
Sbjct: 1938 LQPSEKFAISQSG------ASHSLTISDLVLEDAGQITVEAEG-ASSSAALRVR------ 1984
Query: 305 EPPPIFTRELEDQYVRICEPFTLSCQIVVPPWP 337
E P +F ++LE Q V TL ++ PWP
Sbjct: 1985 EAPVLFKKKLEPQTVEERSSVTLEVEL-TRPWP 2016
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 23/199 (11%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
+ E +L ++ A D+G Y +A A S RV P F L+
Sbjct: 3144 SHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHAR-----------PVRFQEALK 3192
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
DL V G ++SS V W L ++ S+ ++G+
Sbjct: 3193 DLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDS 3251
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR-ALLTEQGTVSLECKVVGVPTP 234
GR++C+ G + SA L V A +F+ +LR TE T +L C+ + P
Sbjct: 3252 GRYSCSF----GDQTTSATLTVTALPA----QFIGKLRNKEATEGATATLRCE-LSKAAP 3302
Query: 235 VLRWFKDSREIKAGDVFAL 253
V W K S ++ GD + L
Sbjct: 3303 V-EWRKGSETLRDGDRYCL 3320
Score = 41.9 bits (94), Expect = 0.003
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 12/142 (8%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ +++ + G E+ S V W + L +R S+ +DG+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL--SKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQ 3858
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V P+ P F E L++L E+G T +L+
Sbjct: 3859 IHGLSVADTGEYSC----VCGQERTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQ 3910
Query: 226 CKVVGVPTPVLRWFKDSREIKA 247
C+ + PT + W K +++A
Sbjct: 3911 CE-LSEPTATVVWSKGGLQLQA 3931
Score = 41.1 bits (92), Expect = 0.006
Identities = 48/219 (21%), Positives = 85/219 (38%), Gaps = 27/219 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V A D G Y+ +A S RL ++ + ++ ++ + G
Sbjct: 1038 RLVVQQAGKTDAGDYSCEARGQRVS----FRLHITEPKMMFAKEQSVH----NEVQAEAG 1089
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V + G G ++C A
Sbjct: 1090 ASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Query: 183 ENVGGRASCSAHLNVLVPKAY--KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
GG+ S HL++ PK K E++A E GT ++ V P + W+K
Sbjct: 1149 ---GGQR-VSFHLHITEPKGVFAKEQSVHNEVQA---EAGTTAMLSCEVAQPQTEVTWYK 1201
Query: 241 DSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
D +++ + G L G Y+CEA
Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 13/104 (12%)
Query: 192 SAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV 250
SA L V +P ++ RP ++++ + TE+ V+LEC++ P +RW KD E++AG
Sbjct: 2156 SARLVVTELPVSFSRP--LQDV--VTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKT 2210
Query: 251 FALTANAEDPTSLGTYTCEAVN-----CMGR-AYSSSKVHVVGR 288
A+ A SL Y CE + C A SS+ V V GR
Sbjct: 2211 MAIAAQGA-CRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGR 2253
Score = 38.7 bits (86), Expect = 0.031
Identities = 58/250 (23%), Positives = 98/250 (39%), Gaps = 30/250 (12%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ L++ G E+ S V W + L + +R S+ +DGS
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V A F+E+++ +G T L+
Sbjct: 3771 IRGLAVVDAGEYSC----VCGQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCE-AVNCMGRAYSSSKVH 284
C+ + PV W K S ++ GD ++L +D T CE ++ + A +
Sbjct: 3823 CE-LSKAAPV-EWRKGSETLRGGDRYSL---RQDGT-----RCELQIHGLSVADTGEYSC 3872
Query: 285 VVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYN 344
V G+ +L + P P+F L+ TL C++ P +VVW
Sbjct: 3873 VCGQERTSATLTVRA------PQPVFREPLQSLQAEEGSTATLQCELSEP--TATVVWSK 3924
Query: 345 KEGKVEAGER 354
+++A R
Sbjct: 3925 GGLQLQANGR 3934
Score = 34.7 bits (76), Expect = 0.50
Identities = 65/295 (22%), Positives = 107/295 (36%), Gaps = 39/295 (13%)
Query: 44 RAGASLD--DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
R GA L ++F ++ LT+S D G T++A A+ S RVR
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR-------- 1984
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
E P F ++L+ TV+ + VE+ ++ W RN L + V I +G+
Sbjct: 1985 ---EAPVLFKKKLEPQTVEERSSVTLEVELTRPWP-ELRWTRNATALAPGKNVEIHAEGA 2040
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQG 220
G + C + +A + + ++ V L+A+ EQG
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--------RQVRLVRGLQAVEAREQG 2092
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT-SLGTYTCEAVNCMGRAYS 279
T ++E ++ W +D + G L T +L E M +
Sbjct: 2093 TATMEVQLSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLM--VFK 2149
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVP 334
+ VH R + E P F+R L+D E TL C++ P
Sbjct: 2150 AEGVHTSARL------------VVTELPVSFSRPLQDVVTTEKEKVTLECELSRP 2192
Score = 34.7 bits (76), Expect = 0.50
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
+P S L+ + P+F EL++Q V+ P + C + P P SV W+ K+GK+
Sbjct: 5114 EPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMP-SVRWF-KDGKL 5165
Score = 34.3 bits (75), Expect = 0.66
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 24/204 (11%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ +E + L V R D+G Y S + G T L V+A P F
Sbjct: 3228 DKYSLRQEGAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTAL-------PAQF 3276
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ +L++ G E+ S V W + L + +R + +DG+
Sbjct: 3277 IGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGL 3334
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
++C V G SA L + A+ F+ LR + +G T +L C+ +
Sbjct: 3335 AMVDAAEYSC----VCGEERTSASLTIRPMPAH----FIGRLRHQESIEGATATLRCE-L 3385
Query: 230 GVPTPVLRWFKDSREIKAGDVFAL 253
PV W K ++ GD +L
Sbjct: 3386 SKAAPV-EWRKGRESLRDGDRHSL 3408
Score = 31.1 bits (67), Expect = 6.1
Identities = 61/246 (24%), Positives = 88/246 (35%), Gaps = 33/246 (13%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
++E +RLT+S D+ YT G +R +L V ED L+
Sbjct: 2964 SQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGRRVHIIED-------LE 3012
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI-VRDGSFFCXXXXXXXXXX 174
D+ V+ G+ F I + V W+ ++ L E I + G +
Sbjct: 3013 DVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKD 3072
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G T E RAS + + P + R E A +TE ++L C+ P
Sbjct: 3073 SG--TIYFEAGDQRASAALRVTE-KPSVFSR----ELTDATITEGEDLTLVCETSTCDIP 3125
Query: 235 VLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
V W KD + ++ G L G Y CEA G A SSS V V
Sbjct: 3126 VC-WTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 3180
Query: 286 VGRASR 291
R R
Sbjct: 3181 HARPVR 3186
Score = 30.7 bits (66), Expect = 8.1
Identities = 30/118 (25%), Positives = 43/118 (36%), Gaps = 2/118 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXX 166
P FL LQ+ V+ G F + V W+++ + L E + I D
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGTVS 223
G + C AEN G +S A L V L Y E + + QG +S
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 50 DDRF-VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
DD + ++ ++ GG +L ++ D GVY A N+ G + + L V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 71.3 bits (167), Expect = 5e-12
Identities = 52/215 (24%), Positives = 90/215 (41%), Gaps = 15/215 (6%)
Query: 100 ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD 159
+ P P FL R + V VG +I+ + +V+W ++++ + R + +D
Sbjct: 2 DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK--AYKRPEFVEELRALLT 217
G + G++ C A N G A + L V A + P F+ ++
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121
Query: 218 EQGT-VSLECKVVGVPTPVLRWFKDSREI-----------KAGDVFALTANAEDPTSLGT 265
+G+ + C+V G P P + W KD R + + G+ AL A P GT
Sbjct: 122 REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181
Query: 266 YTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
Y A N +G A S++ VV + + + +P +S
Sbjct: 182 YEVRAENPLGAA-SAAAALVVDSDAADTASRPGTS 215
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 6127
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 6188 LGSARASAELRI 6199
Score = 66.1 bits (154), Expect = 2e-10
Identities = 91/344 (26%), Positives = 131/344 (38%), Gaps = 62/344 (18%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
RF ++ RLT+ GD+G Y +A NA G A V L+V A E+ E P FL
Sbjct: 55 RFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-EAACAEQAPHFL 113
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXX 169
R + V+ G+ F + S V+W ++ RRL E + RV + G
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNV-----------------LVPKAYKRPEFVEEL 212
G + AEN G AS +A L V L+ +R E +
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAE 233
Query: 213 RALLTEQGTVSLECKV------------VGVPTPVLRWFKDSREIKAGDVFALTANAED- 259
A + T + C V G P P W KD + + G + +A++
Sbjct: 234 GAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQEN 293
Query: 260 ---------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
+ G YTC A N +G+ YSS V VV R EP F
Sbjct: 294 FVLKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVR----------------EPAVPF 335
Query: 311 TRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ L+D VR E T C+ VP W+ +E ++ A +
Sbjct: 336 KKRLQDLEVREKESATFLCE--VPQPSTEAAWFKEETRLWASAK 377
Score = 54.4 bits (125), Expect = 6e-07
Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
+RF+ + RL +T D G Y+ + G D+ RL VS + ++
Sbjct: 842 ERFLQEDVGTRHRLVAATVTRQDEGTYSCRV----GEDSVDFRLRVSEPKVVFAKEQLA- 896
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
R+LQ + G E+ + + +VTWY++ ++L + +V + G
Sbjct: 897 RRKLQ---AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQA 952
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVG 230
G ++C A GG+ S HL+V PK + V + +L C+V
Sbjct: 953 GQADAGEYSCEA---GGQR-LSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQ 1008
Query: 231 VPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
T V+ W+KD +++ + G L T G Y+CEA
Sbjct: 1009 AQTEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056
Score = 53.2 bits (122), Expect = 1e-06
Identities = 57/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 2792 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 2850
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 2851 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 2908
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 2909 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 2961
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
G LT +A + TYTC+ +G+A S +++ V GR
Sbjct: 2962 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGR 3003
Score = 52.0 bits (119), Expect = 3e-06
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)
Query: 206 PEFVEELRALLTEQGT--VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTAN------- 256
P+ VEELR L GT + KV G P P L WFKD + + A +T
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 257 --AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTREL 314
+ G Y N MG AYSS+++ V R E KP S PP
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLV--RGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 315 EDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ V+ T S ++ P P +V W +E +
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVP-TVHWLREEAE 5410
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 6000 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 6058
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 6059 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 6110
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ +V E +C I P+P+ + WY + G +
Sbjct: 6111 VNKVRASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 6153
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 16/194 (8%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V D G Y+ +A G +L ++ ++ ++ ++ + G
Sbjct: 1222 RLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVH----NEVRTEAG 1273
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V I G G +TC A
Sbjct: 1274 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV-SLECKVVGVPTPVLRWFKD 241
GG+ S HL+V PKA E + R + E G + +L C+V T V W+KD
Sbjct: 1333 ---GGQ-RLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQAQTEV-TWYKD 1386
Query: 242 SREIKAGDVFALTA 255
+++ + + A
Sbjct: 1387 GKKLSSSSKVRMEA 1400
Score = 49.6 bits (113), Expect = 2e-05
Identities = 61/256 (23%), Positives = 100/256 (39%), Gaps = 19/256 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA----EESPSGED-----PPTFLRRL 114
L + + D+G Y SNA G+ + RL V EE P+ + PP L R
Sbjct: 5318 LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 115 QDLTVKVGTRTRFLVEIISSTECKVTWYRNE--RRLL----EAERVSIVRDGSFFCXXXX 168
VK G+ F V++ V W R E R +L + ++
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLL 5437
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECK 227
G +TC A N G+A CSA L+V +PK ++ + E L + + T ++ +
Sbjct: 5438 DVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQ 5497
Query: 228 VVGVPT-PVLRWFKDSREIKAGDVFALTANAEDPTS--LGTYTCEAVNCMGRAYSSSKVH 284
+ + L + + A + + AE T L T + + + +K+
Sbjct: 5498 GLETASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQ 5557
Query: 285 VVGRASREGSLKPNSS 300
V G S E S P++S
Sbjct: 5558 VPGGDSDEDSKTPSAS 5573
Score = 48.4 bits (110), Expect = 4e-05
Identities = 49/205 (23%), Positives = 75/205 (36%), Gaps = 17/205 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+YT ASN G + V + V P F +RLQDL V+
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVP-------FKKRLQDLEVREKE 348
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
FL E + + W++ E RL + + I +G+ + C
Sbjct: 349 SATFLCE-VPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETP 407
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G R A L V K P R G ++ C + VP + W ++
Sbjct: 408 E-GSRT--VAELAVQGNLLRKLP------RKTAVRVGDTAMFCVELAVPVGPVHWLRNQE 458
Query: 244 EIKAGDVFALTANAEDPTSLGTYTC 268
E+ AG A++A T + C
Sbjct: 459 EVVAGGRVAISAEGTRHTLTISQCC 483
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED----- 259
P F+ EL+ + G VS +C V G P P +RWFKD + ++ D + + + +
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 260 -----PTSLGTYTCEAVNCMGRAYSSSKVHV 285
P +G Y C A N MG + + +++ V
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 46.8 bits (106), Expect = 1e-04
Identities = 60/273 (21%), Positives = 105/273 (38%), Gaps = 26/273 (9%)
Query: 68 TARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG--EDPPTFLRRLQDLTVKVGTRT 125
TA GDT T+ + S R+ ++ P E F R L+ + ++G
Sbjct: 1767 TASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTV 1826
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
E+ S +V W +L +R +V +G G + C + +
Sbjct: 1827 TLACEL-SPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRD- 1884
Query: 186 GGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSRE 244
SA L V VP+ K F+ L ++ E+G + +C VV + WF+D
Sbjct: 1885 ---DHTSAQLTVSVPRVVK---FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGAL 1937
Query: 245 IKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSP 304
++ + FA++ + +++ + + V G AS +L+
Sbjct: 1938 LQPSEKFAISQSG------ASHSLTISDLVLEDAGQITVEAEG-ASSSAALRVR------ 1984
Query: 305 EPPPIFTRELEDQYVRICEPFTLSCQIVVPPWP 337
E P +F ++LE Q V TL ++ PWP
Sbjct: 1985 EAPVLFKKKLEPQTVEERSSVTLEVEL-TRPWP 2016
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 23/199 (11%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
+ E +L ++ A D+G Y +A A S RV P F L+
Sbjct: 3144 SHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHAR-----------PVRFQEALK 3192
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
DL V G ++SS V W L ++ S+ ++G+
Sbjct: 3193 DLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDS 3251
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR-ALLTEQGTVSLECKVVGVPTP 234
GR++C+ G + SA L V A +F+ +LR TE T +L C+ + P
Sbjct: 3252 GRYSCSF----GDQTTSATLTVTALPA----QFIGKLRNKEATEGATATLRCE-LSKAAP 3302
Query: 235 VLRWFKDSREIKAGDVFAL 253
V W K S ++ GD + L
Sbjct: 3303 V-EWRKGSETLRDGDRYCL 3320
Score = 41.9 bits (94), Expect = 0.003
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 12/142 (8%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ +++ + G E+ S V W + L +R S+ +DG+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL--SKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQ 3858
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V P+ P F E L++L E+G T +L+
Sbjct: 3859 IHGLSVADTGEYSC----VCGQERTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQ 3910
Query: 226 CKVVGVPTPVLRWFKDSREIKA 247
C+ + PT + W K +++A
Sbjct: 3911 CE-LSEPTATVVWSKGGLQLQA 3931
Score = 41.1 bits (92), Expect = 0.006
Identities = 48/219 (21%), Positives = 85/219 (38%), Gaps = 27/219 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V A D G Y+ +A S RL ++ + ++ ++ + G
Sbjct: 1038 RLVVQQAGKTDAGDYSCEARGQRVS----FRLHITEPKMMFAKEQSVH----NEVQAEAG 1089
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V + G G ++C A
Sbjct: 1090 ASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Query: 183 ENVGGRASCSAHLNVLVPKAY--KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
GG+ S HL++ PK K E++A E GT ++ V P + W+K
Sbjct: 1149 ---GGQR-VSFHLHITEPKGVFAKEQSVHNEVQA---EAGTTAMLSCEVAQPQTEVTWYK 1201
Query: 241 DSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
D +++ + G L G Y+CEA
Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 13/104 (12%)
Query: 192 SAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV 250
SA L V +P ++ RP ++++ + TE+ V+LEC++ P +RW KD E++AG
Sbjct: 2156 SARLVVTELPVSFSRP--LQDV--VTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKT 2210
Query: 251 FALTANAEDPTSLGTYTCEAVN-----CMGR-AYSSSKVHVVGR 288
A+ A SL Y CE + C A SS+ V V GR
Sbjct: 2211 MAIAAQGA-CRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGR 2253
Score = 38.7 bits (86), Expect = 0.031
Identities = 58/250 (23%), Positives = 98/250 (39%), Gaps = 30/250 (12%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ L++ G E+ S V W + L + +R S+ +DGS
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V A F+E+++ +G T L+
Sbjct: 3771 IRGLAVVDAGEYSC----VCGQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCE-AVNCMGRAYSSSKVH 284
C+ + PV W K S ++ GD ++L +D T CE ++ + A +
Sbjct: 3823 CE-LSKAAPV-EWRKGSETLRGGDRYSL---RQDGT-----RCELQIHGLSVADTGEYSC 3872
Query: 285 VVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYN 344
V G+ +L + P P+F L+ TL C++ P +VVW
Sbjct: 3873 VCGQERTSATLTVRA------PQPVFREPLQSLQAEEGSTATLQCELSEP--TATVVWSK 3924
Query: 345 KEGKVEAGER 354
+++A R
Sbjct: 3925 GGLQLQANGR 3934
Score = 34.7 bits (76), Expect = 0.50
Identities = 65/295 (22%), Positives = 107/295 (36%), Gaps = 39/295 (13%)
Query: 44 RAGASLD--DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
R GA L ++F ++ LT+S D G T++A A+ S RVR
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR-------- 1984
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
E P F ++L+ TV+ + VE+ ++ W RN L + V I +G+
Sbjct: 1985 ---EAPVLFKKKLEPQTVEERSSVTLEVELTRPWP-ELRWTRNATALAPGKNVEIHAEGA 2040
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQG 220
G + C + +A + + ++ V L+A+ EQG
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--------RQVRLVRGLQAVEAREQG 2092
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT-SLGTYTCEAVNCMGRAYS 279
T ++E ++ W +D + G L T +L E M +
Sbjct: 2093 TATMEVQLSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLM--VFK 2149
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVP 334
+ VH R + E P F+R L+D E TL C++ P
Sbjct: 2150 AEGVHTSARL------------VVTELPVSFSRPLQDVVTTEKEKVTLECELSRP 2192
Score = 34.7 bits (76), Expect = 0.50
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
+P S L+ + P+F EL++Q V+ P + C + P P SV W+ K+GK+
Sbjct: 5114 EPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMP-SVRWF-KDGKL 5165
Score = 34.3 bits (75), Expect = 0.66
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 24/204 (11%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ +E + L V R D+G Y S + G T L V+A P F
Sbjct: 3228 DKYSLRQEGAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTAL-------PAQF 3276
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ +L++ G E+ S V W + L + +R + +DG+
Sbjct: 3277 IGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGL 3334
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
++C V G SA L + A+ F+ LR + +G T +L C+ +
Sbjct: 3335 AMVDAAEYSC----VCGEERTSASLTIRPMPAH----FIGRLRHQESIEGATATLRCE-L 3385
Query: 230 GVPTPVLRWFKDSREIKAGDVFAL 253
PV W K ++ GD +L
Sbjct: 3386 SKAAPV-EWRKGRESLRDGDRHSL 3408
Score = 31.1 bits (67), Expect = 6.1
Identities = 61/246 (24%), Positives = 88/246 (35%), Gaps = 33/246 (13%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
++E +RLT+S D+ YT G +R +L V ED L+
Sbjct: 2964 SQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGRRVHIIED-------LE 3012
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI-VRDGSFFCXXXXXXXXXX 174
D+ V+ G+ F I + V W+ ++ L E I + G +
Sbjct: 3013 DVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKD 3072
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G T E RAS + + P + R E A +TE ++L C+ P
Sbjct: 3073 SG--TIYFEAGDQRASAALRVTE-KPSVFSR----ELTDATITEGEDLTLVCETSTCDIP 3125
Query: 235 VLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
V W KD + ++ G L G Y CEA G A SSS V V
Sbjct: 3126 VC-WTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 3180
Query: 286 VGRASR 291
R R
Sbjct: 3181 HARPVR 3186
Score = 30.7 bits (66), Expect = 8.1
Identities = 30/118 (25%), Positives = 43/118 (36%), Gaps = 2/118 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXX 166
P FL LQ+ V+ G F + V W+++ + L E + I D
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGTVS 223
G + C AEN G +S A L V L Y E + + QG +S
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 50 DDRF-VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
DD + ++ ++ GG +L ++ D GVY A N+ G + + L V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 71.3 bits (167), Expect = 5e-12
Identities = 52/215 (24%), Positives = 90/215 (41%), Gaps = 15/215 (6%)
Query: 100 ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD 159
+ P P FL R + V VG +I+ + +V+W ++++ + R + +D
Sbjct: 2 DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK--AYKRPEFVEELRALLT 217
G + G++ C A N G A + L V A + P F+ ++
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121
Query: 218 EQGT-VSLECKVVGVPTPVLRWFKDSREI-----------KAGDVFALTANAEDPTSLGT 265
+G+ + C+V G P P + W KD R + + G+ AL A P GT
Sbjct: 122 REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181
Query: 266 YTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
Y A N +G A S++ VV + + + +P +S
Sbjct: 182 YEVRAENPLGAA-SAAAALVVDSDAADTASRPGTS 215
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 6127
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 6188 LGSARASAELRI 6199
Score = 66.1 bits (154), Expect = 2e-10
Identities = 91/344 (26%), Positives = 131/344 (38%), Gaps = 62/344 (18%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
RF ++ RLT+ GD+G Y +A NA G A V L+V A E+ E P FL
Sbjct: 55 RFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-EAACAEQAPHFL 113
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXX 169
R + V+ G+ F + S V+W ++ RRL E + RV + G
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNV-----------------LVPKAYKRPEFVEEL 212
G + AEN G AS +A L V L+ +R E +
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAE 233
Query: 213 RALLTEQGTVSLECKV------------VGVPTPVLRWFKDSREIKAGDVFALTANAED- 259
A + T + C V G P P W KD + + G + +A++
Sbjct: 234 GAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQEN 293
Query: 260 ---------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
+ G YTC A N +G+ YSS V VV R EP F
Sbjct: 294 FVLKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVR----------------EPAVPF 335
Query: 311 TRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ L+D VR E T C+ VP W+ +E ++ A +
Sbjct: 336 KKRLQDLEVREKESATFLCE--VPQPSTEAAWFKEETRLWASAK 377
Score = 54.4 bits (125), Expect = 6e-07
Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
+RF+ + RL +T D G Y+ + G D+ RL VS + ++
Sbjct: 842 ERFLQEDVGTRHRLVAATVTRQDEGTYSCRV----GEDSVDFRLRVSEPKVVFAKEQLA- 896
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
R+LQ + G E+ + + +VTWY++ ++L + +V + G
Sbjct: 897 RRKLQ---AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQA 952
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVG 230
G ++C A GG+ S HL+V PK + V + +L C+V
Sbjct: 953 GQADAGEYSCEA---GGQR-LSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQ 1008
Query: 231 VPTPVLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
T V+ W+KD +++ + G L T G Y+CEA
Sbjct: 1009 AQTEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056
Score = 53.2 bits (122), Expect = 1e-06
Identities = 57/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 2792 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 2850
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 2851 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 2908
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 2909 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 2961
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
G LT +A + TYTC+ +G+A S +++ V GR
Sbjct: 2962 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGR 3003
Score = 52.0 bits (119), Expect = 3e-06
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)
Query: 206 PEFVEELRALLTEQGT--VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTAN------- 256
P+ VEELR L GT + KV G P P L WFKD + + A +T
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 257 --AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTREL 314
+ G Y N MG AYSS+++ V R E KP S PP
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLV--RGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 315 EDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ V+ T S ++ P P +V W +E +
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVP-TVHWLREEAE 5410
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 6000 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 6058
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 6059 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 6110
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ +V E +C I P+P+ + WY + G +
Sbjct: 6111 VNKVRASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 6153
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 16/194 (8%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V D G Y+ +A G +L ++ ++ ++ ++ + G
Sbjct: 1222 RLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVH----NEVRTEAG 1273
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V I G G +TC A
Sbjct: 1274 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV-SLECKVVGVPTPVLRWFKD 241
GG+ S HL+V PKA E + R + E G + +L C+V T V W+KD
Sbjct: 1333 ---GGQ-RLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQAQTEV-TWYKD 1386
Query: 242 SREIKAGDVFALTA 255
+++ + + A
Sbjct: 1387 GKKLSSSSKVRMEA 1400
Score = 49.6 bits (113), Expect = 2e-05
Identities = 61/256 (23%), Positives = 100/256 (39%), Gaps = 19/256 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA----EESPSGED-----PPTFLRRL 114
L + + D+G Y SNA G+ + RL V EE P+ + PP L R
Sbjct: 5318 LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 115 QDLTVKVGTRTRFLVEIISSTECKVTWYRNE--RRLL----EAERVSIVRDGSFFCXXXX 168
VK G+ F V++ V W R E R +L + ++
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLL 5437
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECK 227
G +TC A N G+A CSA L+V +PK ++ + E L + + T ++ +
Sbjct: 5438 DVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQ 5497
Query: 228 VVGVPT-PVLRWFKDSREIKAGDVFALTANAEDPTS--LGTYTCEAVNCMGRAYSSSKVH 284
+ + L + + A + + AE T L T + + + +K+
Sbjct: 5498 GLETASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQ 5557
Query: 285 VVGRASREGSLKPNSS 300
V G S E S P++S
Sbjct: 5558 VPGGDSDEDSKTPSAS 5573
Score = 48.4 bits (110), Expect = 4e-05
Identities = 49/205 (23%), Positives = 75/205 (36%), Gaps = 17/205 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+YT ASN G + V + V P F +RLQDL V+
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVP-------FKKRLQDLEVREKE 348
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
FL E + + W++ E RL + + I +G+ + C
Sbjct: 349 SATFLCE-VPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETP 407
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G R A L V K P R G ++ C + VP + W ++
Sbjct: 408 E-GSRT--VAELAVQGNLLRKLP------RKTAVRVGDTAMFCVELAVPVGPVHWLRNQE 458
Query: 244 EIKAGDVFALTANAEDPTSLGTYTC 268
E+ AG A++A T + C
Sbjct: 459 EVVAGGRVAISAEGTRHTLTISQCC 483
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED----- 259
P F+ EL+ + G VS +C V G P P +RWFKD + ++ D + + + +
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 260 -----PTSLGTYTCEAVNCMGRAYSSSKVHV 285
P +G Y C A N MG + + +++ V
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 46.8 bits (106), Expect = 1e-04
Identities = 60/273 (21%), Positives = 105/273 (38%), Gaps = 26/273 (9%)
Query: 68 TARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG--EDPPTFLRRLQDLTVKVGTRT 125
TA GDT T+ + S R+ ++ P E F R L+ + ++G
Sbjct: 1767 TASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTV 1826
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
E+ S +V W +L +R +V +G G + C + +
Sbjct: 1827 TLACEL-SPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRD- 1884
Query: 186 GGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSRE 244
SA L V VP+ K F+ L ++ E+G + +C VV + WF+D
Sbjct: 1885 ---DHTSAQLTVSVPRVVK---FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGAL 1937
Query: 245 IKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSP 304
++ + FA++ + +++ + + V G AS +L+
Sbjct: 1938 LQPSEKFAISQSG------ASHSLTISDLVLEDAGQITVEAEG-ASSSAALRVR------ 1984
Query: 305 EPPPIFTRELEDQYVRICEPFTLSCQIVVPPWP 337
E P +F ++LE Q V TL ++ PWP
Sbjct: 1985 EAPVLFKKKLEPQTVEERSSVTLEVEL-TRPWP 2016
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 23/199 (11%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
+ E +L ++ A D+G Y +A A S RV P F L+
Sbjct: 3144 SHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHAR-----------PVRFQEALK 3192
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
DL V G ++SS V W L ++ S+ ++G+
Sbjct: 3193 DLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDS 3251
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR-ALLTEQGTVSLECKVVGVPTP 234
GR++C+ G + SA L V A +F+ +LR TE T +L C+ + P
Sbjct: 3252 GRYSCSF----GDQTTSATLTVTALPA----QFIGKLRNKEATEGATATLRCE-LSKAAP 3302
Query: 235 VLRWFKDSREIKAGDVFAL 253
V W K S ++ GD + L
Sbjct: 3303 V-EWRKGSETLRDGDRYCL 3320
Score = 41.9 bits (94), Expect = 0.003
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 12/142 (8%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ +++ + G E+ S V W + L +R S+ +DG+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL--SKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQ 3858
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V P+ P F E L++L E+G T +L+
Sbjct: 3859 IHGLSVADTGEYSC----VCGQERTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQ 3910
Query: 226 CKVVGVPTPVLRWFKDSREIKA 247
C+ + PT + W K +++A
Sbjct: 3911 CE-LSEPTATVVWSKGGLQLQA 3931
Score = 41.1 bits (92), Expect = 0.006
Identities = 48/219 (21%), Positives = 85/219 (38%), Gaps = 27/219 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V A D G Y+ +A S RL ++ + ++ ++ + G
Sbjct: 1038 RLVVQQAGKTDAGDYSCEARGQRVS----FRLHITEPKMMFAKEQSVH----NEVQAEAG 1089
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V + G G ++C A
Sbjct: 1090 ASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Query: 183 ENVGGRASCSAHLNVLVPKAY--KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
GG+ S HL++ PK K E++A E GT ++ V P + W+K
Sbjct: 1149 ---GGQR-VSFHLHITEPKGVFAKEQSVHNEVQA---EAGTTAMLSCEVAQPQTEVTWYK 1201
Query: 241 DSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
D +++ + G L G Y+CEA
Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 13/104 (12%)
Query: 192 SAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV 250
SA L V +P ++ RP ++++ + TE+ V+LEC++ P +RW KD E++AG
Sbjct: 2156 SARLVVTELPVSFSRP--LQDV--VTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKT 2210
Query: 251 FALTANAEDPTSLGTYTCEAVN-----CMGR-AYSSSKVHVVGR 288
A+ A SL Y CE + C A SS+ V V GR
Sbjct: 2211 MAIAAQGA-CRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGR 2253
Score = 38.7 bits (86), Expect = 0.031
Identities = 58/250 (23%), Positives = 98/250 (39%), Gaps = 30/250 (12%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ L++ G E+ S V W + L + +R S+ +DGS
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V A F+E+++ +G T L+
Sbjct: 3771 IRGLAVVDAGEYSC----VCGQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCE-AVNCMGRAYSSSKVH 284
C+ + PV W K S ++ GD ++L +D T CE ++ + A +
Sbjct: 3823 CE-LSKAAPV-EWRKGSETLRGGDRYSL---RQDGT-----RCELQIHGLSVADTGEYSC 3872
Query: 285 VVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYN 344
V G+ +L + P P+F L+ TL C++ P +VVW
Sbjct: 3873 VCGQERTSATLTVRA------PQPVFREPLQSLQAEEGSTATLQCELSEP--TATVVWSK 3924
Query: 345 KEGKVEAGER 354
+++A R
Sbjct: 3925 GGLQLQANGR 3934
Score = 34.7 bits (76), Expect = 0.50
Identities = 65/295 (22%), Positives = 107/295 (36%), Gaps = 39/295 (13%)
Query: 44 RAGASLD--DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
R GA L ++F ++ LT+S D G T++A A+ S RVR
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR-------- 1984
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
E P F ++L+ TV+ + VE+ ++ W RN L + V I +G+
Sbjct: 1985 ---EAPVLFKKKLEPQTVEERSSVTLEVELTRPWP-ELRWTRNATALAPGKNVEIHAEGA 2040
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQG 220
G + C + +A + + ++ V L+A+ EQG
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--------RQVRLVRGLQAVEAREQG 2092
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT-SLGTYTCEAVNCMGRAYS 279
T ++E ++ W +D + G L T +L E M +
Sbjct: 2093 TATMEVQLSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLM--VFK 2149
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVP 334
+ VH R + E P F+R L+D E TL C++ P
Sbjct: 2150 AEGVHTSARL------------VVTELPVSFSRPLQDVVTTEKEKVTLECELSRP 2192
Score = 34.7 bits (76), Expect = 0.50
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
+P S L+ + P+F EL++Q V+ P + C + P P SV W+ K+GK+
Sbjct: 5114 EPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMP-SVRWF-KDGKL 5165
Score = 34.3 bits (75), Expect = 0.66
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 24/204 (11%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ +E + L V R D+G Y S + G T L V+A P F
Sbjct: 3228 DKYSLRQEGAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTAL-------PAQF 3276
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ +L++ G E+ S V W + L + +R + +DG+
Sbjct: 3277 IGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGL 3334
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
++C V G SA L + A+ F+ LR + +G T +L C+ +
Sbjct: 3335 AMVDAAEYSC----VCGEERTSASLTIRPMPAH----FIGRLRHQESIEGATATLRCE-L 3385
Query: 230 GVPTPVLRWFKDSREIKAGDVFAL 253
PV W K ++ GD +L
Sbjct: 3386 SKAAPV-EWRKGRESLRDGDRHSL 3408
Score = 31.1 bits (67), Expect = 6.1
Identities = 61/246 (24%), Positives = 88/246 (35%), Gaps = 33/246 (13%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
++E +RLT+S D+ YT G +R +L V ED L+
Sbjct: 2964 SQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGRRVHIIED-------LE 3012
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI-VRDGSFFCXXXXXXXXXX 174
D+ V+ G+ F I + V W+ ++ L E I + G +
Sbjct: 3013 DVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKD 3072
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G T E RAS + + P + R E A +TE ++L C+ P
Sbjct: 3073 SG--TIYFEAGDQRASAALRVTE-KPSVFSR----ELTDATITEGEDLTLVCETSTCDIP 3125
Query: 235 VLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
V W KD + ++ G L G Y CEA G A SSS V V
Sbjct: 3126 VC-WTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 3180
Query: 286 VGRASR 291
R R
Sbjct: 3181 HARPVR 3186
Score = 30.7 bits (66), Expect = 8.1
Identities = 30/118 (25%), Positives = 43/118 (36%), Gaps = 2/118 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXX 166
P FL LQ+ V+ G F + V W+++ + L E + I D
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGTVS 223
G + C AEN G +S A L V L Y E + + QG +S
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 50 DDRF-VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
DD + ++ ++ GG +L ++ D GVY A N+ G + + L V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 71.3 bits (167), Expect = 5e-12
Identities = 52/215 (24%), Positives = 90/215 (41%), Gaps = 15/215 (6%)
Query: 100 ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD 159
+ P P FL R + V VG +I+ + +V+W ++++ + R + +D
Sbjct: 2 DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQD 61
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK--AYKRPEFVEELRALLT 217
G + G++ C A N G A + L V A + P F+ ++
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121
Query: 218 EQGT-VSLECKVVGVPTPVLRWFKDSREI-----------KAGDVFALTANAEDPTSLGT 265
+G+ + C+V G P P + W KD R + + G+ AL A P GT
Sbjct: 122 REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181
Query: 266 YTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
Y A N +G A S++ VV + + + +P +S
Sbjct: 182 YEVRAENPLGAA-SAAAALVVDSDAADTASRPGTS 215
Score = 68.1 bits (159), Expect = 4e-11
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++ A +G
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVLASPFVEGEDAQF 6127
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 6188 LGSARASAELRI 6199
Score = 66.1 bits (154), Expect = 2e-10
Identities = 91/344 (26%), Positives = 131/344 (38%), Gaps = 62/344 (18%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
RF ++ RLT+ GD+G Y +A NA G A V L+V A E+ E P FL
Sbjct: 55 RFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-EAACAEQAPHFL 113
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE--RVSIVRDGSFFCXXXXX 169
R + V+ G+ F + S V+W ++ RRL E + RV + G
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNV-----------------LVPKAYKRPEFVEEL 212
G + AEN G AS +A L V L+ +R E +
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAE 233
Query: 213 RALLTEQGTVSLECKV------------VGVPTPVLRWFKDSREIKAGDVFALTANAED- 259
A + T + C V G P P W KD + + G + +A++
Sbjct: 234 GAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQEN 293
Query: 260 ---------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
+ G YTC A N +G+ YSS V VV R EP F
Sbjct: 294 FVLKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVR----------------EPAVPF 335
Query: 311 TRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ L+D VR E T C+ VP W+ +E ++ A +
Sbjct: 336 KKRLQDLEVREKESATFLCE--VPQPSTEAAWFKEETRLWASAK 377
Score = 53.2 bits (122), Expect = 1e-06
Identities = 57/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 2792 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 2850
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 2851 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 2908
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 2909 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 2961
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
G LT +A + TYTC+ +G+A S +++ V GR
Sbjct: 2962 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGR 3003
Score = 52.8 bits (121), Expect = 2e-06
Identities = 42/165 (25%), Positives = 68/165 (41%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 6000 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 6058
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 6059 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 6110
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ L +V E +C I P+P+ + WY + G +
Sbjct: 6111 VNKVLASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 6153
Score = 52.0 bits (119), Expect = 3e-06
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)
Query: 206 PEFVEELRALLTEQGT--VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTAN------- 256
P+ VEELR L GT + KV G P P L WFKD + + A +T
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 257 --AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTREL 314
+ G Y N MG AYSS+++ V R E KP S PP
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLV--RGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 315 EDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ V+ T S ++ P P +V W +E +
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVP-TVHWLREEAE 5410
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 16/194 (8%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V D G Y+ +A G +L ++ ++ ++ ++ + G
Sbjct: 1222 RLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVH----NEVRTEAG 1273
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V I G G +TC A
Sbjct: 1274 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV-SLECKVVGVPTPVLRWFKD 241
GG+ S HL+V PKA E + R + E G + +L C+V T V W+KD
Sbjct: 1333 ---GGQ-RLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQAQTEV-TWYKD 1386
Query: 242 SREIKAGDVFALTA 255
+++ + + A
Sbjct: 1387 GKKLSSSSKVRMEA 1400
Score = 48.8 bits (111), Expect = 3e-05
Identities = 61/256 (23%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA----EESPSGED-----PPTFLRRL 114
L + + D+G Y SNA G+ + RL V EE P+ + PP L R
Sbjct: 5318 LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 115 QDLTVKVGTRTRFLVEIISSTECKVTWYRNE--RRLL----EAERVSIVRDGSFFCXXXX 168
VK G+ F V++ V W R E R +L + ++
Sbjct: 5378 TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLL 5437
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECK 227
G +TC A N G+A CSA L+V +PK ++ + E L + + T ++ +
Sbjct: 5438 DVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQ 5497
Query: 228 VVGVPT-PVLRWFKDSREIKAGDVFALTANAEDPTS--LGTYTCEAVNCMGRAYSSSKVH 284
+ L + + A + + AE T L T + + + +K+
Sbjct: 5498 GFQTASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQ 5557
Query: 285 VVGRASREGSLKPNSS 300
V G S E S P++S
Sbjct: 5558 VPGGDSDEDSKTPSAS 5573
Score = 48.4 bits (110), Expect = 4e-05
Identities = 49/205 (23%), Positives = 75/205 (36%), Gaps = 17/205 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+YT ASN G + V + V P F +RLQDL V+
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVP-------FKKRLQDLEVREKE 348
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
FL E + + W++ E RL + + I +G+ + C
Sbjct: 349 SATFLCE-VPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETP 407
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G R A L V K P R G ++ C + VP + W ++
Sbjct: 408 E-GSRT--VAELAVQGNLLRKLP------RKTAVRVGDTAMFCVELAVPVGPVHWLRNQE 458
Query: 244 EIKAGDVFALTANAEDPTSLGTYTC 268
E+ AG A++A T + C
Sbjct: 459 EVVAGGRVAISAEGTRHTLTISQCC 483
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED----- 259
P F+ EL+ + G VS +C V G P P +RWFKD + ++ D + + + +
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 260 -----PTSLGTYTCEAVNCMGRAYSSSKVHV 285
P +G Y C A N MG + + +++ V
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 44.0 bits (99), Expect = 8e-04
Identities = 59/273 (21%), Positives = 104/273 (38%), Gaps = 26/273 (9%)
Query: 68 TARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG--EDPPTFLRRLQDLTVKVGTRT 125
TA GDT T+ + S R+ ++ P E F R L+ + ++G
Sbjct: 1767 TASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTV 1826
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
E+ S +V W + +R +V +G G + C + +
Sbjct: 1827 TLACEL-SPACAEVVWRCGNTQPRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRD- 1884
Query: 186 GGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSRE 244
SA L V VP+ K F+ L ++ E+G + +C VV + WF+D
Sbjct: 1885 ---DHTSAQLTVSVPRVVK---FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGAL 1937
Query: 245 IKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSP 304
++ + FA++ + +++ + + V G AS +L+
Sbjct: 1938 LQPSEKFAISQSG------ASHSLTISDLVLEDAGQITVEAEG-ASSSAALRVR------ 1984
Query: 305 EPPPIFTRELEDQYVRICEPFTLSCQIVVPPWP 337
E P +F ++LE Q V TL ++ PWP
Sbjct: 1985 EAPVLFKKKLEPQTVEERSSVTLEVEL-TRPWP 2016
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 23/199 (11%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
+ E +L ++ A D+G Y +A A S RV P F L+
Sbjct: 3144 SHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHAR-----------PVRFQEALK 3192
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
DL V G ++SS V W L ++ S+ ++G+
Sbjct: 3193 DLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDS 3251
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR-ALLTEQGTVSLECKVVGVPTP 234
GR++C+ G + SA L V A +F+ +LR TE T +L C++ T
Sbjct: 3252 GRYSCSF----GDQTTSATLTVTALPA----QFIGKLRNKEATEGATATLRCEL--SKTA 3301
Query: 235 VLRWFKDSREIKAGDVFAL 253
+ W K S ++ GD + L
Sbjct: 3302 PVEWRKGSETLRDGDRYCL 3320
Score = 41.9 bits (94), Expect = 0.003
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 12/142 (8%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ +++ + G E+ S V W + L +R S+ +DG+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL--SKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQ 3858
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V P+ P F E L++L E+G T +L+
Sbjct: 3859 IHGLSVADTGEYSC----VCGQERTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQ 3910
Query: 226 CKVVGVPTPVLRWFKDSREIKA 247
C+ + PT + W K +++A
Sbjct: 3911 CE-LSEPTATVVWSKGGLQLQA 3931
Score = 41.1 bits (92), Expect = 0.006
Identities = 48/219 (21%), Positives = 85/219 (38%), Gaps = 27/219 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V A D G Y+ +A S RL ++ + ++ ++ + G
Sbjct: 1038 RLVVQQAGKTDAGDYSCEARGQRVS----FRLHITEPKMMFAKEQSVH----NEVQAEAG 1089
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V + G G ++C A
Sbjct: 1090 ASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Query: 183 ENVGGRASCSAHLNVLVPKAY--KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
GG+ S HL++ PK K E++A E GT ++ V P + W+K
Sbjct: 1149 ---GGQR-VSFHLHITEPKGVFAKEQSVHNEVQA---EAGTTAMLSCEVAQPQTEVTWYK 1201
Query: 241 DSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
D +++ + G L G Y+CEA
Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 13/104 (12%)
Query: 192 SAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV 250
SA L V +P ++ RP ++++ + TE+ V+LEC++ P +RW KD E++AG
Sbjct: 2156 SARLVVTELPVSFSRP--LQDV--VTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKT 2210
Query: 251 FALTANAEDPTSLGTYTCEAVN-----CMGR-AYSSSKVHVVGR 288
A+ A SL Y CE + C A SS+ V V GR
Sbjct: 2211 MAIAAQGA-CRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGR 2253
Score = 38.7 bits (86), Expect = 0.031
Identities = 58/250 (23%), Positives = 98/250 (39%), Gaps = 30/250 (12%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ L++ G E+ S V W + L + +R S+ +DGS
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V A F+E+++ +G T L+
Sbjct: 3771 IRGLAVVDAGEYSC----VCGQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCE-AVNCMGRAYSSSKVH 284
C+ + PV W K S ++ GD ++L +D T CE ++ + A +
Sbjct: 3823 CE-LSKAAPV-EWRKGSETLRGGDRYSL---RQDGT-----RCELQIHGLSVADTGEYSC 3872
Query: 285 VVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYN 344
V G+ +L + P P+F L+ TL C++ P +VVW
Sbjct: 3873 VCGQERTSATLTVRA------PQPVFREPLQSLQAEEGSTATLQCELSEP--TATVVWSK 3924
Query: 345 KEGKVEAGER 354
+++A R
Sbjct: 3925 GGLQLQANGR 3934
Score = 34.7 bits (76), Expect = 0.50
Identities = 65/295 (22%), Positives = 107/295 (36%), Gaps = 39/295 (13%)
Query: 44 RAGASLD--DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
R GA L ++F ++ LT+S D G T++A A+ S RVR
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR-------- 1984
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
E P F ++L+ TV+ + VE+ ++ W RN L + V I +G+
Sbjct: 1985 ---EAPVLFKKKLEPQTVEERSSVTLEVELTRPWP-ELRWTRNATALAPGKNVEIHAEGA 2040
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQG 220
G + C + +A + + ++ V L+A+ EQG
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--------RQVRLVRGLQAVEAREQG 2092
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT-SLGTYTCEAVNCMGRAYS 279
T ++E ++ W +D + G L T +L E M +
Sbjct: 2093 TATMEVQLSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLM--VFK 2149
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVP 334
+ VH R + E P F+R L+D E TL C++ P
Sbjct: 2150 AEGVHTSARL------------VVTELPVSFSRPLQDVVTTEKEKVTLECELSRP 2192
Score = 34.7 bits (76), Expect = 0.50
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
+P S L+ + P+F EL++Q V+ P + C + P P SV W+ K+GK+
Sbjct: 5114 EPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMP-SVRWF-KDGKL 5165
Score = 34.3 bits (75), Expect = 0.66
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 24/204 (11%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ +E + L V R D+G Y S + G T L V+A P F
Sbjct: 3228 DKYSLRQEGAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTAL-------PAQF 3276
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ +L++ G E+ S V W + L + +R + +DG+
Sbjct: 3277 IGKLRNKEATEGATATLRCEL--SKTAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGL 3334
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
++C V G SA L + A+ F+ LR + +G T +L C+ +
Sbjct: 3335 AMVDAAEYSC----VCGEERTSASLTIRPMPAH----FIGRLRHQESIEGATATLRCE-L 3385
Query: 230 GVPTPVLRWFKDSREIKAGDVFAL 253
PV W K ++ GD +L
Sbjct: 3386 SKAAPV-EWRKGRESLRDGDRHSL 3408
Score = 30.7 bits (66), Expect = 8.1
Identities = 30/118 (25%), Positives = 43/118 (36%), Gaps = 2/118 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXX 166
P FL LQ+ V+ G F + V W+++ + L E + I D
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGTVS 223
G + C AEN G +S A L V L Y E + + QG +S
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 50 DDRF-VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
DD + ++ ++ GG +L ++ D GVY A N+ G + + L V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B
protein.
Length = 1960
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 5 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 64
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 65 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 119
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 120 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 179
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 180 LGSARASAELRI 191
Score = 55.6 bits (128), Expect = 2e-07
Identities = 26/92 (28%), Positives = 47/92 (51%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP+ ++D+ + G +F I + VTWY++ +L+++ R+S ++G+ +
Sbjct: 348 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 407
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
G +TC A+N GG+ C A L VL
Sbjct: 408 LRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 439
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 11/153 (7%)
Query: 203 YKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT 261
++ P+F EEL E G TV L C+V G P PV+ W+KD + ++ L EDP
Sbjct: 3 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHIL---IEDPD 59
Query: 262 SLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRI 321
+++ + S ++ AS G+ L PP + +V
Sbjct: 60 GSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVE- 113
Query: 322 CEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
E +C I P+P+ + WY + G +
Sbjct: 114 GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 145
Score = 35.9 bits (79), Expect = 0.22
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 220 GTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEA 270
GT E + G P P + W+KDS ++ + G ++L G YTC A
Sbjct: 364 GTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLA 423
Query: 271 VNCMGRAYSSSKVHVVGRASREGSLK 296
N G+ +++ V+G + S K
Sbjct: 424 QNTGGQVLCKAELLVLGGDNEPDSEK 449
Score = 35.5 bits (78), Expect = 0.28
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GS 161
S + PTFLR L D TV +G ++ + + TW ++ L + RV I +
Sbjct: 1450 SWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKN 1509
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHL 195
F G +TC+ N G + + L
Sbjct: 1510 FQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 1543
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 300 SGL-SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
SGL S + P F REL D+ V + + TL+CQ+ P W +E+ R
Sbjct: 1446 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQP-AAQATWSKDGAPLESSSR 1500
Score = 31.1 bits (67), Expect = 6.1
Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 11/98 (11%)
Query: 204 KRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED--- 259
+ P F+ EL G +V+L C+V P W KD +++ ++A ++
Sbjct: 1453 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 1512
Query: 260 -------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
LG YTC N +G ++ + R S
Sbjct: 1513 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPS 1550
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 743
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 744 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 803
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 804 LGSARASAELRI 815
Score = 55.6 bits (128), Expect = 2e-07
Identities = 26/92 (28%), Positives = 47/92 (51%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP+ ++D+ + G +F I + VTWY++ +L+++ R+S ++G+ +
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
G +TC A+N GG+ C A L VL
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 616 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 674
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 675 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 726
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ +V E +C I P+P+ + WY + G +
Sbjct: 727 VNKVRASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 769
Score = 35.9 bits (79), Expect = 0.22
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 220 GTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEA 270
GT E + G P P + W+KDS ++ + G ++L G YTC A
Sbjct: 988 GTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLA 1047
Query: 271 VNCMGRAYSSSKVHVVGRASREGSLK 296
N G+ +++ V+G + S K
Sbjct: 1048 QNTGGQVLCKAELLVLGGDNEPDSEK 1073
Score = 35.5 bits (78), Expect = 0.28
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GS 161
S + PTFLR L D TV +G ++ + + TW ++ L + RV I +
Sbjct: 2074 SWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKN 2133
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHL 195
F G +TC+ N G + + L
Sbjct: 2134 FQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167
Score = 35.1 bits (77), Expect = 0.38
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 4/129 (3%)
Query: 176 GRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPT- 233
G +TC A N G+A CSA L+V +PK ++ + E L + + T ++ + + +
Sbjct: 60 GTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASF 119
Query: 234 PVLRWFKDSREIKAGDVFALTANAEDPTS--LGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
L + + A + + AE T L T + + + +K+ V G S
Sbjct: 120 ADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQVPGGDSD 179
Query: 292 EGSLKPNSS 300
E S P++S
Sbjct: 180 EDSKTPSAS 188
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 300 SGL-SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
SGL S + P F REL D+ V + + TL+CQ+ P W +E+ R
Sbjct: 2070 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQP-AAQATWSKDGAPLESSSR 2124
Score = 31.1 bits (67), Expect = 6.1
Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 11/98 (11%)
Query: 204 KRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED--- 259
+ P F+ EL G +V+L C+V P W KD +++ ++A ++
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136
Query: 260 -------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
LG YTC N +G ++ + R S
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPS 2174
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 743
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 744 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 803
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 804 LGSARASAELRI 815
Score = 55.6 bits (128), Expect = 2e-07
Identities = 26/92 (28%), Positives = 47/92 (51%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP+ ++D+ + G +F I + VTWY++ +L+++ R+S ++G+ +
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
G +TC A+N GG+ C A L VL
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 616 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 674
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 675 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 726
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ +V E +C I P+P+ + WY + G +
Sbjct: 727 VNKVRASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 769
Score = 35.9 bits (79), Expect = 0.22
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 220 GTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEA 270
GT E + G P P + W+KDS ++ + G ++L G YTC A
Sbjct: 988 GTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLA 1047
Query: 271 VNCMGRAYSSSKVHVVGRASREGSLK 296
N G+ +++ V+G + S K
Sbjct: 1048 QNTGGQVLCKAELLVLGGDNEPDSEK 1073
Score = 35.5 bits (78), Expect = 0.28
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GS 161
S + PTFLR L D TV +G ++ + + TW ++ L + RV I +
Sbjct: 2074 SWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKN 2133
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHL 195
F G +TC+ N G + + L
Sbjct: 2134 FQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167
Score = 35.1 bits (77), Expect = 0.38
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 4/129 (3%)
Query: 176 GRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPT- 233
G +TC A N G+A CSA L+V +PK ++ + E L + + T ++ + + +
Sbjct: 60 GTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASF 119
Query: 234 PVLRWFKDSREIKAGDVFALTANAEDPTS--LGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
L + + A + + AE T L T + + + +K+ V G S
Sbjct: 120 ADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQVPGGDSD 179
Query: 292 EGSLKPNSS 300
E S P++S
Sbjct: 180 EDSKTPSAS 188
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 300 SGL-SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
SGL S + P F REL D+ V + + TL+CQ+ P W +E+ R
Sbjct: 2070 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQP-AAQATWSKDGAPLESSSR 2124
Score = 31.1 bits (67), Expect = 6.1
Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 11/98 (11%)
Query: 204 KRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED--- 259
+ P F+ EL G +V+L C+V P W KD +++ ++A ++
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136
Query: 260 -------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
LG YTC N +G ++ + R S
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPS 2174
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 413 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 472
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 473 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 527
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 528 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 587
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 588 LGSARASAELRI 599
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 400 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 458
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 459 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 510
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ +V E +C I P+P+ + WY + G +
Sbjct: 511 VNKVRASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 553
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 70.9 bits (166), Expect = 6e-12
Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 18/192 (9%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP F L D T ++G + + + + ++WY++ + + ++ D C
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 167 XXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSL 224
G++ C A + G S + V VP P FV ++RA +G
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQF 743
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVF-----------ALTANAEDPTSLGTYTCEAVNC 273
C + G P P +RW+KD + G+ F L A LG Y CE VN
Sbjct: 744 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 803
Query: 274 MGRAYSSSKVHV 285
+G A +S+++ +
Sbjct: 804 LGSARASAELRI 815
Score = 55.6 bits (128), Expect = 2e-07
Identities = 26/92 (28%), Positives = 47/92 (51%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP+ ++D+ + G +F I + VTWY++ +L+++ R+S ++G+ +
Sbjct: 972 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
G +TC A+N GG+ C A L VL
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063
Score = 50.4 bits (115), Expect = 9e-06
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 12/165 (7%)
Query: 191 CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD 249
C + +P ++ P+F EEL E G TV L C+V G P PV+ W+KD + ++
Sbjct: 616 CGIQQRLALP-VWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDP 674
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPI 309
L EDP +++ + S ++ AS G+ L PP
Sbjct: 675 HHIL---IEDPDGSCALILDSLTGV-----DSGQYMCFAASAAGNCSTLGKILVQVPPRF 726
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ +V E +C I P+P+ + WY + G +
Sbjct: 727 VNKVRASPFVE-GEDAQFTCTIEGAPYPQ-IRWYKDGALLTTGNK 769
Score = 35.9 bits (79), Expect = 0.22
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 220 GTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEA 270
GT E + G P P + W+KDS ++ + G ++L G YTC A
Sbjct: 988 GTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLA 1047
Query: 271 VNCMGRAYSSSKVHVVGRASREGSLK 296
N G+ +++ V+G + S K
Sbjct: 1048 QNTGGQVLCKAELLVLGGDNEPDSEK 1073
Score = 35.5 bits (78), Expect = 0.28
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GS 161
S + PTFLR L D TV +G ++ + + TW ++ L + RV I +
Sbjct: 2074 SWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKN 2133
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHL 195
F G +TC+ N G + + L
Sbjct: 2134 FQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167
Score = 35.1 bits (77), Expect = 0.38
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 4/129 (3%)
Query: 176 GRWTCTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPT- 233
G +TC A N G+A CSA L+V +PK ++ + E L + + T ++ + + +
Sbjct: 60 GTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASF 119
Query: 234 PVLRWFKDSREIKAGDVFALTANAEDPTS--LGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
L + + A + + AE T L T + + + +K+ V G S
Sbjct: 120 ADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQVPGGDSD 179
Query: 292 EGSLKPNSS 300
E S P++S
Sbjct: 180 EDSKTPSAS 188
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 300 SGL-SPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
SGL S + P F REL D+ V + + TL+CQ+ P W +E+ R
Sbjct: 2070 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQP-AAQATWSKDGAPLESSSR 2124
Score = 31.1 bits (67), Expect = 6.1
Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 11/98 (11%)
Query: 204 KRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED--- 259
+ P F+ EL G +V+L C+V P W KD +++ ++A ++
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136
Query: 260 -------PTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
LG YTC N +G ++ + R S
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPS 2174
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/297 (27%), Positives = 119/297 (40%), Gaps = 24/297 (8%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G +L +S D G+Y ASN AG + EV E PS FLRR + V
Sbjct: 218 GGKLMMSHTLKSDAGMYVCVASNMAG-ERESAAAEVMVLERPS------FLRRPVNQVVL 270
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
FL E+ ++ W R E L R I D S + G +TC
Sbjct: 271 ADAPVTFLCEVKGDPPPRLRW-RKEDGELPTGRYEIRSDHSLWIGHVSAEDE---GTYTC 326
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWF 239
AEN GRA S L+V VP P+ V + + + G +V+ +C+ G P P + W
Sbjct: 327 VAENSVGRAEASGSLSVHVP-----PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQ 381
Query: 240 KDSREIKAGDVFALTANAEDPTS-LGTYTCEAVNCMGRA--YSSSKVHVVGRASREGSLK 296
K+ ++ +L S G AV G A Y V V G + L+
Sbjct: 382 KEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQ-RGDAGYYMCQAVSVAGSILAKALLE 440
Query: 297 PNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ L PP+ + +Q + + L C++ P P SV W K+G+ G+
Sbjct: 441 IKGASLD-GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQP-SVRW-KKDGQWLQGD 494
Score = 64.9 bits (151), Expect = 4e-10
Identities = 62/221 (28%), Positives = 90/221 (40%), Gaps = 22/221 (9%)
Query: 73 DTGVYTLQASNAAGSDTAR-VRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEI 131
D GVYT A N G+ +R LEV+ + P + + + V R
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPR----- 191
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RAS 190
E V+W ++ RL E E +R G G + C A N+ G R S
Sbjct: 192 -GHPEPSVSWRKDGARLKEEEGRITIRGGKLM---MSHTLKSDAGMYVCVASNMAGERES 247
Query: 191 CSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG- 248
+A + VL +RP F+ + ++ V+ C+V G P P LRW K+ E+ G
Sbjct: 248 AAAEVMVL-----ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGR 302
Query: 249 ----DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+L GTYTC A N +GRA +S + V
Sbjct: 303 YEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV 343
Score = 49.6 bits (113), Expect = 2e-05
Identities = 65/245 (26%), Positives = 89/245 (36%), Gaps = 25/245 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G YT A N+ G R E S S S PP + + QD G F E
Sbjct: 320 DEGTYTCVAENSVG------RAEASG--SLSVHVPPQLVTQPQDQMAAPGESVAFQCETK 371
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCX-----XXXXXXXXXXGRWTCTAENVGG 187
+ + W + ++L S+ G F G + C A +V G
Sbjct: 372 GNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAG 431
Query: 188 RASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPTPVLRWFKDSREI 245
A L + P + + A L +V L C+V G P P +RW KD + +
Sbjct: 432 SILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWL 491
Query: 246 KAGDV-FALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSS-GL 302
+ D+ F AN GT V M YS G A+ G LK G+
Sbjct: 492 QGDDLQFKTMAN-------GTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGV 544
Query: 303 SPEPP 307
SP+PP
Sbjct: 545 SPDPP 549
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 69.7 bits (163), Expect = 1e-11
Identities = 82/297 (27%), Positives = 119/297 (40%), Gaps = 24/297 (8%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G +L +S D G+Y ASN AG + EV E PS FLRR + V
Sbjct: 218 GGKLMMSHTLKSDAGMYVCVASNMAG-ERESAAAEVMVLERPS------FLRRPVNQVVL 270
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
FL E+ ++ W R E L R I D S + G +TC
Sbjct: 271 ADAPVTFLCEVKGDPPPRLRW-RKEDGELPTGRYEIRSDHSLWIGHVSAEDE---GTYTC 326
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWF 239
AEN GRA S L+V VP P+ V + + + G +V+ +C+ G P P + W
Sbjct: 327 VAENSVGRAEASGSLSVHVP-----PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQ 381
Query: 240 KDSREIKAGDVFALTANAEDPTS-LGTYTCEAVNCMGRA--YSSSKVHVVGRASREGSLK 296
K+ ++ +L S G AV G A Y V V G + L+
Sbjct: 382 KEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQ-RGDAGYYVCQAVSVAGSILAKALLE 440
Query: 297 PNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ L PP+ + +Q + + L C++ P P SV W K+G+ G+
Sbjct: 441 IKGASLD-GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQP-SVRW-KKDGQWLQGD 494
Score = 64.9 bits (151), Expect = 4e-10
Identities = 62/221 (28%), Positives = 90/221 (40%), Gaps = 22/221 (9%)
Query: 73 DTGVYTLQASNAAGSDTAR-VRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEI 131
D GVYT A N G+ +R LEV+ + P + + + V R
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPR----- 191
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RAS 190
E V+W ++ RL E E +R G G + C A N+ G R S
Sbjct: 192 -GHPEPSVSWRKDGARLKEEEGRITIRGGKLM---MSHTLKSDAGMYVCVASNMAGERES 247
Query: 191 CSAHLNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG- 248
+A + VL +RP F+ + ++ V+ C+V G P P LRW K+ E+ G
Sbjct: 248 AAAEVMVL-----ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGR 302
Query: 249 ----DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+L GTYTC A N +GRA +S + V
Sbjct: 303 YEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV 343
Score = 50.0 bits (114), Expect = 1e-05
Identities = 65/245 (26%), Positives = 89/245 (36%), Gaps = 25/245 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G YT A N+ G R E S S S PP + + QD G F E
Sbjct: 320 DEGTYTCVAENSVG------RAEASG--SLSVHVPPQLVTQPQDQMAAPGESVAFQCETK 371
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCX-----XXXXXXXXXXGRWTCTAENVGG 187
+ + W + ++L S+ G F G + C A +V G
Sbjct: 372 GNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAG 431
Query: 188 RASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPTPVLRWFKDSREI 245
A L + P + + A L +V L C+V G P P +RW KD + +
Sbjct: 432 SILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWL 491
Query: 246 KAGDV-FALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREGSLKPNSS-GL 302
+ D+ F AN GT V M YS G A+ G LK G+
Sbjct: 492 QGDDLQFKTMAN-------GTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGV 544
Query: 303 SPEPP 307
SP+PP
Sbjct: 545 SPDPP 549
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 9/196 (4%)
Query: 15 VRRSATLDIHPQYDRWRHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDT 74
VR T+ +HP+ HV + K + G + D ++ + G +LT+++ T D
Sbjct: 2934 VRFGVTITVHPE-----PHVTWYKSGQKIKPGDN-DKKYTFESDKGLYQLTINSVTTDDD 2987
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIIS 133
YT+ A N G D+ + +L V+ P+ P F R L + + G F + +
Sbjct: 2988 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 3047
Query: 134 STECKVTWYRNERRLLEAERVSIVRDG-SFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
+ W ++ + L + I+ +G ++ G + TA N G SC
Sbjct: 3048 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQ 3107
Query: 193 AHLNVLVPKAYKRPEF 208
AHL V YK+ EF
Sbjct: 3108 AHLQV-ERLRYKKQEF 3122
Score = 63.7 bits (148), Expect = 9e-10
Identities = 53/199 (26%), Positives = 77/199 (38%), Gaps = 18/199 (9%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGS 161
E PP F L + T VG RF V I E VTWY++ +++ + + + D
Sbjct: 2914 ERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG 2973
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV----PKAYKRPEFVEELRALLT 217
+ +T A N G SC A L V + + RP F L
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAEC 3033
Query: 218 EQG-TVSLECKVVGVPTPVLRWFKDSREIKAG----------DVFALTANAEDPTSLGTY 266
++G +V E +V G+P P L+W KD + + G D +AL P G Y
Sbjct: 3034 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 3093
Query: 267 TCEAVNCMGRAYSSSKVHV 285
A N G + + V
Sbjct: 3094 RVTATNTAGSTSCQAHLQV 3112
Score = 53.6 bits (123), Expect = 1e-06
Identities = 39/183 (21%), Positives = 72/183 (39%), Gaps = 3/183 (1%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
A N G R R +S + + + P + ++D+T K+G + +I+ +
Sbjct: 1734 AENETGLSRPR-RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK 1792
Query: 141 WYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
WYR + L+++ + + DG G +TC A N G S+ L +L
Sbjct: 1793 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQA 1851
Query: 201 KAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDP 260
P + + + T+ L +G P P + WF + ++ + + N E
Sbjct: 1852 TPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITI-ENTEHY 1910
Query: 261 TSL 263
T L
Sbjct: 1911 THL 1913
Score = 50.4 bits (115), Expect = 9e-06
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+ A D G+ T + G + L +S E S D P F+ + + + G
Sbjct: 4321 LTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS----DAPAFISQPRSQNINEGQ 4376
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F EI ++ W++N + + VSI R + + G++T A+
Sbjct: 4377 NVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAK 4436
Query: 184 NVGGRASCSAHLNVL 198
N G+ S +A L VL
Sbjct: 4437 NFRGQCSATASLMVL 4451
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
Query: 183 ENVGGRASCSAHLNVLVPKA---YKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRW 238
EN+GG + S + PK+ + P F EELR L + Q +L CKV G P P+++W
Sbjct: 2129 ENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKW 2188
Query: 239 FKDSREIKA 247
++ +EI A
Sbjct: 2189 YRQGKEIIA 2197
Score = 47.2 bits (107), Expect = 9e-05
Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 9/193 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP---PTF 110
V+TEE +V G + ++ N G E+S +P + P P F
Sbjct: 2101 VTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWS---EISEPITPKSDVPIQAPHF 2157
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD--GSFFCXXXX 168
L++L V+ + + ++ + V WYR + ++ +++ G +
Sbjct: 2158 KEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIA 2217
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECK 227
+ A N GG S +A L V VP P+ +E + A+ +G VS++
Sbjct: 2218 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIP 2277
Query: 228 VVGVPTPVLRWFK 240
G P PV+ W K
Sbjct: 2278 FSGKPDPVITWQK 2290
Score = 45.2 bits (102), Expect = 4e-04
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 10/88 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P +E++ + T+ G + L C++VG P P ++W++ +E+ G LT
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
E+ G YTC A N +G +SSK+
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKL 1847
Score = 41.5 bits (93), Expect = 0.004
Identities = 26/120 (21%), Positives = 43/120 (35%), Gaps = 4/120 (3%)
Query: 82 SNAAGSDTARVRLEVSAEESPSGEDP----PTFLRRLQDLTVKVGTRTRFLVEIISSTEC 137
S SD V+ + P +P P + LQD TV + +F V+
Sbjct: 4049 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 4108
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
W ++ + + + + + D F G +TCT +N G S S L +
Sbjct: 4109 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 4168
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/180 (21%), Positives = 71/180 (39%), Gaps = 13/180 (7%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+++ G R I +T+ K W N L +E GS G
Sbjct: 4275 MSINEGQRLVLKANIAGATDVK--WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 4332
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV 235
TC ++ G C L L + P F+ + R+ +G V ++ G P+P
Sbjct: 4333 ILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRSQNINEGQNVLFTREISGEPSPE 4391
Query: 236 LRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ WFK++ I ++ +V++L + G YT +A N G+ +++ + V+
Sbjct: 4392 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 4451
Score = 39.1 bits (87), Expect = 0.023
Identities = 24/109 (22%), Positives = 42/109 (38%)
Query: 89 TARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL 148
T+ + EV +++ + + P R++ V G TRF++ + S +V WY N L
Sbjct: 3582 TSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL 3641
Query: 149 LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
E+ ++ G + N G S A L+V
Sbjct: 3642 QESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690
Score = 39.1 bits (87), Expect = 0.023
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
TK + ++ +E+ GG L + T D+G+YT N+AGS ++ +L + A +
Sbjct: 4113 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 4172
Query: 101 SPSGEDPPTFLRRLQDLT--VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
+ T ++ ++T K + + + S E K++ +++ +L E S V
Sbjct: 4173 DTEAQKVST--QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 4229
Score = 38.3 bits (85), Expect = 0.040
Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 3/137 (2%)
Query: 65 TVSTARTGDTGVYTLQASNAAG--SDTARVRLEVSAEESPSGEDPPTFLRRLQDL-TVKV 121
TV+ GDT + + A NAAG S + V+ + + R DL T++
Sbjct: 229 TVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRA 288
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
G+ + E K+ W + ++ L E+VS+ G G++T T
Sbjct: 289 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 348
Query: 182 AENVGGRASCSAHLNVL 198
+N G + S + VL
Sbjct: 349 VKNASGTKAVSVMVKVL 365
Score = 35.1 bits (77), Expect = 0.38
Identities = 29/128 (22%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 205 RPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANA------ 257
+P V L+ +V+ K G P P W KD + I G + L+ +
Sbjct: 4078 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 4137
Query: 258 ---EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS--LKPNSSGLSPEPPPIFTR 312
D + G YTC N G SS K+ + E +S ++P+ +
Sbjct: 4138 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 4197
Query: 313 ELEDQYVR 320
E+ + +R
Sbjct: 4198 EISQKALR 4205
Score = 34.3 bits (75), Expect = 0.66
Identities = 48/210 (22%), Positives = 80/210 (38%), Gaps = 13/210 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV T D GVYT A+N G +L + A +P P L+ + VG+
Sbjct: 1817 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA--TPQFH-PGYPLK--EKYYGAVGS 1871
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF-FCXXXXXXXXXXXGRWTCTA 182
R V I +TW+ ++ L +E ++I + G++
Sbjct: 1872 TLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 1931
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
NV G + A L+V + +P + ALL +S + + + + +
Sbjct: 1932 SNVFG--TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 1989
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVN 272
E K G + L ++A + TC VN
Sbjct: 1990 CEAKEGAEWQLVSSA-----ISVTTCRIVN 2014
Score = 32.7 bits (71), Expect = 2.0
Identities = 32/127 (25%), Positives = 47/127 (37%), Gaps = 10/127 (7%)
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPTPVLR 237
C A G A + V Y E E + + + G + L + G P P+ +
Sbjct: 1337 CNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICK 1396
Query: 238 WFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA- 289
W K+ ++I + A L D GTY N G+ KV V+G
Sbjct: 1397 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPN 1456
Query: 290 SREGSLK 296
S EG L+
Sbjct: 1457 SPEGPLE 1463
>AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein.
Length = 1106
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/146 (28%), Positives = 70/146 (47%), Gaps = 5/146 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + + D G+YT A+N AG ++ + L V+A+E+ PP F+ +LQ+
Sbjct: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA---HKPPVFIEKLQNT 1019
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDG-SFFCXXXXXXXXXXX 175
V G R ++ ++ W + NE +RVS+ +D + C
Sbjct: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPK 201
G +T +A+N G SC+A L+V + +
Sbjct: 1080 GWYTVSAKNEAGIVSCTARLDVYISR 1105
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ DLTV+ G R ++ ++W + + + ++ +VR+
Sbjct: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G +TC A N G+ S S L V +A+K P F+E+L+ G V LE
Sbjct: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1030
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+GVP P + W K++ +
Sbjct: 1031 CRVLGVPPPQIFWKKENESL 1050
Score = 54.4 bits (125), Expect = 6e-07
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREI----------KAGDVFALT 254
P F+++LR+ +G+ V LEC+V G PTP +RWF + +E+ + GD+ L
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
G YTC A N G +S++V + G +S +
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD 368
Score = 47.6 bits (108), Expect = 7e-05
Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 27/172 (15%)
Query: 188 RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIK 246
R+ S N + + + RP F++ L ++G + ++CKV G+PTP L W D + ++
Sbjct: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
Query: 247 AGDVFALTANAEDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREGSLK 296
+ SL G YTC A N G+ S ++ V + + +
Sbjct: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---- 1008
Query: 297 PNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
PP+F +L++ V P L C+++ P P+ +++ KE +
Sbjct: 1009 ----------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENE 1048
Score = 44.4 bits (100), Expect = 6e-04
Identities = 43/139 (30%), Positives = 60/139 (43%), Gaps = 25/139 (17%)
Query: 202 AYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL------- 253
AY P F +EL+ +G V LEC+V G P ++WF+ EI+ F +
Sbjct: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496
Query: 254 TANAED----------PTSLGTYTCEAVNCMGRAYSSSKVHVVG----RASREGSLKPNS 299
TA E+ P G +TC A N G A S++++ V S E + N+
Sbjct: 497 TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNN 556
Query: 300 SGLS--PEPPPIF-TRELE 315
P PPPI T LE
Sbjct: 557 DHFQHFPPPPPILETSSLE 575
Score = 38.7 bits (86), Expect = 0.031
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIK-AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
V+ C+V G P P + WFKD ++I D + + + + SL T T ++ G Y+
Sbjct: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT-TASTLDDDGN-YTI 851
Query: 281 SKVHVVGRASREGSL---KPNSSGLSPEPP 307
+ GR S G L N G SP P
Sbjct: 852 MAANPQGRISCTGRLMVQAVNQRGRSPRSP 881
Score = 34.3 bits (75), Expect = 0.66
Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCX- 165
P F +L+ + G F + + + K+ W+++ +++ +++ +I RD C
Sbjct: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +T A N GR SC+ L V
Sbjct: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
Score = 33.5 bits (73), Expect = 1.1
Identities = 20/89 (22%), Positives = 34/89 (38%), Gaps = 1/89 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI-VRDGSFFCXX 166
P F+++L+ V G+R + + +V W+ + L + I G
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHL 195
GR+TC A N G + SA +
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEV 359
Score = 31.1 bits (67), Expect = 6.1
Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 307 PPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVE 350
PP+FT+EL++ V + L C++ P P V W+ + +++
Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAP-PLQVQWFRQGSEIQ 482
>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
Length = 2242
Score = 65.7 bits (153), Expect = 2e-10
Identities = 71/259 (27%), Positives = 101/259 (38%), Gaps = 42/259 (16%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
+L +++ D+GVYT + S A T RL V +P F R L+D+ V G
Sbjct: 44 KLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAP------LFTRLLEDVEVLEG 97
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
RF +I + VTW + E+E + + +DG G + +A
Sbjct: 98 RAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSA 157
Query: 183 ENVGGRASCSAHLNVLVP---------KAYKRPEFVEE--------------LRALL-TE 218
N G+A CSA L V P K K P EE LR L E
Sbjct: 158 VNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLE 217
Query: 219 QGTVS---LECKVVGVPTPVLRWFKDSREIKAG---------DVFALTANAEDPTSLGTY 266
G LEC+V G+P P + WF + I++ DV L A P G Y
Sbjct: 218 VGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVY 277
Query: 267 TCEAVNCMGRAYSSSKVHV 285
N +G+A + ++V
Sbjct: 278 KSVIANKLGKAACYAHLYV 296
Score = 60.9 bits (141), Expect = 7e-09
Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 32 HHVRAFILNTKSRAGASLDDRF----VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGS 87
+HV A ++ +S GA L+ R +S + L + D G T A N G+
Sbjct: 433 NHVEAQVV-WRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGT 491
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
T V LE++ + P F ++D+ V G RF V + + WY++E
Sbjct: 492 QTCSVTLELA--------EAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVL 543
Query: 148 LLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
L E+ VS V + + G +TCTA+N+ G SC A L V
Sbjct: 544 LTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 593
Score = 57.2 bits (132), Expect = 8e-08
Identities = 60/254 (23%), Positives = 100/254 (39%), Gaps = 25/254 (9%)
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
G F + T+ +V W R L A + + DG G +TC
Sbjct: 1 GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 60
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW-- 238
+CSA L V A +E++ L E +CK+ G P PV+ W
Sbjct: 61 KLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVL--EGRAARFDCKISGTPPPVVTWTH 118
Query: 239 ----FKDSREIKA---GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG-RAS 290
++S ++ G + +L G Y AVN G+A+ S++++V R +
Sbjct: 119 FGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTA 178
Query: 291 REG-SLKPNSSGLSPEPP----------PIFTRELEDQYVRICEPFTLSCQIVVPPWPRS 339
G S K PE P P F R L+D V + + L CQ+ P+P +
Sbjct: 179 ASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYP-T 237
Query: 340 VVWYNKEGKVEAGE 353
+ W++ ++++ +
Sbjct: 238 ISWFHNGHRIQSSD 251
Score = 43.6 bits (98), Expect = 0.001
Identities = 50/203 (24%), Positives = 75/203 (36%), Gaps = 25/203 (12%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
E P+ E+ P L + D+ V + + + E +V W LLEA R +
Sbjct: 400 EHGPTLEEAPAMLDK-PDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEA-RAGVYE 457
Query: 159 ----DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
D +C G TCTA N G +CS L + +A + +E++
Sbjct: 458 LSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELA--EAPRFESIMEDVEV 515
Query: 215 LLTEQGTVSLECKVVGVPTPVLRWFKDS------------REIKAGDVFALTANAEDPTS 262
E T V G P P + W+KD E + L+ A+D
Sbjct: 516 GAGE--TARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDG-- 571
Query: 263 LGTYTCEAVNCMGRAYSSSKVHV 285
G YTC A N G +++ V
Sbjct: 572 -GVYTCTAQNLAGEVSCKAELAV 593
>BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein
protein.
Length = 143
Score = 64.9 bits (151), Expect = 4e-10
Identities = 39/140 (27%), Positives = 68/140 (48%), Gaps = 5/140 (3%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+YT A+N AG ++ + L V+A+E+ PP F+ +LQ+ V G
Sbjct: 6 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA---HKPPVFIEKLQNTGVADGY 62
Query: 124 RTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDG-SFFCXXXXXXXXXXXGRWTCT 181
R ++ ++ W + NE +RVS+ +D + C G +T +
Sbjct: 63 PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 122
Query: 182 AENVGGRASCSAHLNVLVPK 201
A+N G SC+A L+V + +
Sbjct: 123 AKNEAGIVSCTARLDVYISR 142
Score = 54.0 bits (124), Expect = 8e-07
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTP 234
G +TC A N G+ S S L V +A+K P F+E+L+ G V LEC+V+GVP P
Sbjct: 17 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP 76
Query: 235 VLRWFKDSREI 245
+ W K++ +
Sbjct: 77 QIFWKKENESL 87
>BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein.
Length = 510
Score = 64.5 bits (150), Expect = 5e-10
Identities = 41/142 (28%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + + D G+YT A+N AG ++ + L V+A+E+ PP F+ +LQ+
Sbjct: 314 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA---HKPPVFIEKLQNT 370
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDG-SFFCXXXXXXXXXXX 175
V G R ++ ++ W + NE +RVS+ +D + C
Sbjct: 371 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 430
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L+V
Sbjct: 431 GWYTVSAKNEAGIVSCTARLDV 452
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ DLTV+ G R ++ ++W + + + ++ +VR+
Sbjct: 262 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 321
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G +TC A N G+ S S L V +A+K P F+E+L+ G V LE
Sbjct: 322 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 381
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+GVP P + W K++ +
Sbjct: 382 CRVLGVPPPQIFWKKENESL 401
Score = 47.6 bits (108), Expect = 7e-05
Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 27/172 (15%)
Query: 188 RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIK 246
R+ S N + + + RP F++ L ++G + ++CKV G+PTP L W D + ++
Sbjct: 244 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 303
Query: 247 AGDVFALTANAEDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREGSLK 296
+ SL G YTC A N G+ S ++ V + + +
Sbjct: 304 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---- 359
Query: 297 PNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
PP+F +L++ V P L C+++ P P+ +++ KE +
Sbjct: 360 ----------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENE 399
Score = 38.7 bits (86), Expect = 0.031
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIK-AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
V+ C+V G P P + WFKD ++I D + + + + SL T T ++ G Y+
Sbjct: 145 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT-TASTLDDDGN-YTI 202
Query: 281 SKVHVVGRASREGSL---KPNSSGLSPEPP 307
+ GR S G L N G SP P
Sbjct: 203 MAANPQGRISCTGRLMVQAVNQRGRSPRSP 232
Score = 34.3 bits (75), Expect = 0.66
Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCX- 165
P F +L+ + G F + + + K+ W+++ +++ +++ +I RD C
Sbjct: 128 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 187
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +T A N GR SC+ L V
Sbjct: 188 HTTASTLDDDGNYTIMAANPQGRISCTGRLMV 219
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 64.5 bits (150), Expect = 5e-10
Identities = 73/292 (25%), Positives = 118/292 (40%), Gaps = 41/292 (14%)
Query: 64 LTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
L + R D GVY A N+AG + T L S+ + P+F+ + QD V +G
Sbjct: 290 LMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPA-----KPSFVIQPQDTEVLIG 344
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
T T +TW R+ L+ R G + GR+TC A
Sbjct: 345 TSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYL----QNITQRDHGRFTCHA 400
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKD 241
N G +A++ V P P+F V ++ E+ V C+ G P PV+ W K
Sbjct: 401 NNSHGTVQAAANIIVQAP-----PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKT 455
Query: 242 SREIKA-GDVFALTA-----NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ G L++ + G Y C+AV+ +G V + S + ++
Sbjct: 456 GGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG----------VKKVSVQLTV 505
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
KP + +FT+ +D V + + +SC P P ++ +NKEG
Sbjct: 506 KPKALA-------VFTQLPQDTSVEVGKNINISCHAQGEPQP--IITWNKEG 548
Score = 42.7 bits (96), Expect = 0.002
Identities = 42/179 (23%), Positives = 73/179 (40%), Gaps = 12/179 (6%)
Query: 115 QDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAE-RVSIVRDGSFFCXXXXXXXX 172
QD+ V G F + + ++ W N L LE + R+++ DG+
Sbjct: 241 QDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQ 300
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGV 231
G + C A N G A + + + +P FV + + GT +LEC G
Sbjct: 301 ---GVYQCMARNSAGEAKTQSAM-LRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGH 356
Query: 232 PTPVLRWFKDSREIKAGDVFALTANA---EDPTSL--GTYTCEAVNCMGRAYSSSKVHV 285
P P++ W +D+ G T++ ++ T G +TC A N G +++ + V
Sbjct: 357 PHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIV 415
Score = 39.9 bits (89), Expect = 0.013
Identities = 61/255 (23%), Positives = 96/255 (37%), Gaps = 26/255 (10%)
Query: 46 GASLD-DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSG 104
G LD R V+T + G+ L T R D G +T A+N+ G+ A + V A
Sbjct: 368 GLELDGSRHVAT--SSGLYLQNITQR--DHGRFTCHANNSHGTVQAAANIIVQA------ 417
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFC 164
PP F +D V +L E + + W + +L + +++ G+
Sbjct: 418 --PPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTL-- 473
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVS 223
G++ C A + G S L V PKA F + + E G ++
Sbjct: 474 -RIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVK-PKALA--VFTQLPQDTSVEVGKNIN 529
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVF------ALTANAEDPTSLGTYTCEAVNCMGRA 277
+ C G P P++ W K+ +I F LT G Y C A N G A
Sbjct: 530 ISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLA 589
Query: 278 YSSSKVHVVGRASRE 292
++ + V R+
Sbjct: 590 VTNMFLTVTAIQGRQ 604
>AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein.
Length = 404
Score = 64.5 bits (150), Expect = 5e-10
Identities = 41/142 (28%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + + D G+YT A+N AG ++ + L V+A+E+ PP F+ +LQ+
Sbjct: 208 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA---HKPPVFIEKLQNT 264
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDG-SFFCXXXXXXXXXXX 175
V G R ++ ++ W + NE +RVS+ +D + C
Sbjct: 265 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 324
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L+V
Sbjct: 325 GWYTVSAKNEAGIVSCTARLDV 346
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ DLTV+ G R ++ ++W + + + ++ +VR+
Sbjct: 156 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 215
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G +TC A N G+ S S L V +A+K P F+E+L+ G V LE
Sbjct: 216 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 275
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+GVP P + W K++ +
Sbjct: 276 CRVLGVPPPQIFWKKENESL 295
Score = 47.6 bits (108), Expect = 7e-05
Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 27/172 (15%)
Query: 188 RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIK 246
R+ S N + + + RP F++ L ++G + ++CKV G+PTP L W D + ++
Sbjct: 138 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 197
Query: 247 AGDVFALTANAEDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREGSLK 296
+ SL G YTC A N G+ S ++ V + + +
Sbjct: 198 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---- 253
Query: 297 PNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
PP+F +L++ V P L C+++ P P+ +++ KE +
Sbjct: 254 ----------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENE 293
Score = 38.7 bits (86), Expect = 0.031
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIK-AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
V+ C+V G P P + WFKD ++I D + + + + SL T T ++ G Y+
Sbjct: 39 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT-TASTLDDDGN-YTI 96
Query: 281 SKVHVVGRASREGSL---KPNSSGLSPEPP 307
+ GR S G L N G SP P
Sbjct: 97 MAANPQGRISCTGRLMVQAVNQRGRSPRSP 126
Score = 34.3 bits (75), Expect = 0.66
Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCX- 165
P F +L+ + G F + + + K+ W+++ +++ +++ +I RD C
Sbjct: 22 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 81
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +T A N GR SC+ L V
Sbjct: 82 HTTASTLDDDGNYTIMAANPQGRISCTGRLMV 113
>AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein.
Length = 772
Score = 64.5 bits (150), Expect = 5e-10
Identities = 41/142 (28%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + + D G+YT A+N AG ++ + L V+A+E+ PP F+ +LQ+
Sbjct: 576 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA---HKPPVFIEKLQNT 632
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDG-SFFCXXXXXXXXXXX 175
V G R ++ ++ W + NE +RVS+ +D + C
Sbjct: 633 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 692
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L+V
Sbjct: 693 GWYTVSAKNEAGIVSCTARLDV 714
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ DLTV+ G R ++ ++W + + + ++ +VR+
Sbjct: 524 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 583
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G +TC A N G+ S S L V +A+K P F+E+L+ G V LE
Sbjct: 584 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 643
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+GVP P + W K++ +
Sbjct: 644 CRVLGVPPPQIFWKKENESL 663
Score = 47.6 bits (108), Expect = 7e-05
Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 27/172 (15%)
Query: 188 RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIK 246
R+ S N + + + RP F++ L ++G + ++CKV G+PTP L W D + ++
Sbjct: 506 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 565
Query: 247 AGDVFALTANAEDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREGSLK 296
+ SL G YTC A N G+ S ++ V + + +
Sbjct: 566 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---- 621
Query: 297 PNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
PP+F +L++ V P L C+++ P P+ +++ KE +
Sbjct: 622 ----------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENE 661
Score = 38.7 bits (86), Expect = 0.031
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIK-AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
V+ C+V G P P + WFKD ++I D + + + + SL T T ++ G Y+
Sbjct: 407 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT-TASTLDDDGN-YTI 464
Query: 281 SKVHVVGRASREGSL---KPNSSGLSPEPP 307
+ GR S G L N G SP P
Sbjct: 465 MAANPQGRISCTGRLMVQAVNQRGRSPRSP 494
Score = 34.3 bits (75), Expect = 0.66
Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCX- 165
P F +L+ + G F + + + K+ W+++ +++ +++ +I RD C
Sbjct: 390 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 449
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +T A N GR SC+ L V
Sbjct: 450 HTTASTLDDDGNYTIMAANPQGRISCTGRLMV 481
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 63.7 bits (148), Expect = 9e-10
Identities = 75/302 (24%), Positives = 114/302 (37%), Gaps = 23/302 (7%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGEDP 107
+DD+ GG +L +S R D G+YT +N G D+ L V +
Sbjct: 174 IDDKEERISIRGG-KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVF--------ER 224
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
PTFLRR + V F ++ + V W +++ L R I D +
Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD---YTLRI 280
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLEC 226
G + C AEN G+ SA L V P P+FV R + QG TV+ C
Sbjct: 281 KKTMSTDEGTYMCIAENRVGKMEASATLTVRAP-----PQFVVRPRDQIVAQGRTVTFPC 335
Query: 227 KVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTS-LGTYTCEAVNCMGRAYSSSKVHV 285
+ G P P + W K+ + N+ S G T + Y +
Sbjct: 336 ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALT 395
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + + + L+ PPPI + +Q + + L C+ P P V+ + K
Sbjct: 396 VAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLP--VISWLK 453
Query: 346 EG 347
EG
Sbjct: 454 EG 455
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 15/157 (9%)
Query: 136 ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAEN-VGGRASCSAH 194
E + W +++ R+ + E +R G G +TC N VG R S A
Sbjct: 162 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDA---GMYTCVGTNMVGERDSDPAE 218
Query: 195 LNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG----- 248
L V ++RP F+ + ++ E+ V C+V G P P +RW KD ++ G
Sbjct: 219 LTV-----FERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIK 273
Query: 249 DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
D + L T GTY C A N +G+ +S+ + V
Sbjct: 274 DDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 310
Score = 48.0 bits (109), Expect = 5e-05
Identities = 61/239 (25%), Positives = 81/239 (33%), Gaps = 28/239 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y A N G A L V A PP F+ R +D V G
Sbjct: 278 LRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA--------PPQFVVRPRDQIVAQGR 329
Query: 124 RTRFLVEIISSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXX 175
F E + + V W + + LL R S+ G
Sbjct: 330 TVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL---TITNIQRSDA 386
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPT 233
G + C A V G A L V + P + + A L GT L+CK G P
Sbjct: 387 GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL 446
Query: 234 PVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
PV+ W K+ D A L + GTYTC A + G S+ + V
Sbjct: 447 PVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505
Score = 35.5 bits (78), Expect = 0.28
Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIK 246
P VE ++ +G +L CK G PTP + W+KD ++
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVE 72
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 63.7 bits (148), Expect = 9e-10
Identities = 75/302 (24%), Positives = 114/302 (37%), Gaps = 23/302 (7%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGEDP 107
+DD+ GG +L +S R D G+YT +N G D+ L V +
Sbjct: 190 IDDKEERISIRGG-KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVF--------ER 240
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
PTFLRR + V F ++ + V W +++ L R I D +
Sbjct: 241 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD---YTLRI 296
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLEC 226
G + C AEN G+ SA L V P P+FV R + QG TV+ C
Sbjct: 297 KKTMSTDEGTYMCIAENRVGKMEASATLTVRAP-----PQFVVRPRDQIVAQGRTVTFPC 351
Query: 227 KVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTS-LGTYTCEAVNCMGRAYSSSKVHV 285
+ G P P + W K+ + N+ S G T + Y +
Sbjct: 352 ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALT 411
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + + + L+ PPPI + +Q + + L C+ P P V+ + K
Sbjct: 412 VAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLP--VISWLK 469
Query: 346 EG 347
EG
Sbjct: 470 EG 471
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 15/157 (9%)
Query: 136 ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAEN-VGGRASCSAH 194
E + W +++ R+ + E +R G G +TC N VG R S A
Sbjct: 178 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDA---GMYTCVGTNMVGERDSDPAE 234
Query: 195 LNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG----- 248
L V ++RP F+ + ++ E+ V C+V G P P +RW KD ++ G
Sbjct: 235 LTV-----FERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIK 289
Query: 249 DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
D + L T GTY C A N +G+ +S+ + V
Sbjct: 290 DDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 326
Score = 48.0 bits (109), Expect = 5e-05
Identities = 61/239 (25%), Positives = 81/239 (33%), Gaps = 28/239 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y A N G A L V A PP F+ R +D V G
Sbjct: 294 LRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA--------PPQFVVRPRDQIVAQGR 345
Query: 124 RTRFLVEIISSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXX 175
F E + + V W + + LL R S+ G
Sbjct: 346 TVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL---TITNIQRSDA 402
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPT 233
G + C A V G A L V + P + + A L GT L+CK G P
Sbjct: 403 GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL 462
Query: 234 PVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
PV+ W K+ D A L + GTYTC A + G S+ + V
Sbjct: 463 PVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 521
Score = 35.5 bits (78), Expect = 0.28
Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIK 246
P VE ++ +G +L CK G PTP + W+KD ++
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVE 88
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 63.7 bits (148), Expect = 9e-10
Identities = 75/302 (24%), Positives = 114/302 (37%), Gaps = 23/302 (7%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGEDP 107
+DD+ GG +L +S R D G+YT +N G D+ L V +
Sbjct: 176 IDDKEERISIRGG-KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVF--------ER 226
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
PTFLRR + V F ++ + V W +++ L R I D +
Sbjct: 227 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD---YTLRI 282
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLEC 226
G + C AEN G+ SA L V P P+FV R + QG TV+ C
Sbjct: 283 KKTMSTDEGTYMCIAENRVGKMEASATLTVRAP-----PQFVVRPRDQIVAQGRTVTFPC 337
Query: 227 KVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTS-LGTYTCEAVNCMGRAYSSSKVHV 285
+ G P P + W K+ + N+ S G T + Y +
Sbjct: 338 ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALT 397
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + + + L+ PPPI + +Q + + L C+ P P V+ + K
Sbjct: 398 VAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLP--VISWLK 455
Query: 346 EG 347
EG
Sbjct: 456 EG 457
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 15/157 (9%)
Query: 136 ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAEN-VGGRASCSAH 194
E + W +++ R+ + E +R G G +TC N VG R S A
Sbjct: 164 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDA---GMYTCVGTNMVGERDSDPAE 220
Query: 195 LNVLVPKAYKRPEFVEE-LRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG----- 248
L V ++RP F+ + ++ E+ V C+V G P P +RW KD ++ G
Sbjct: 221 LTV-----FERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIK 275
Query: 249 DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
D + L T GTY C A N +G+ +S+ + V
Sbjct: 276 DDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 312
Score = 48.0 bits (109), Expect = 5e-05
Identities = 61/239 (25%), Positives = 81/239 (33%), Gaps = 28/239 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y A N G A L V A PP F+ R +D V G
Sbjct: 280 LRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA--------PPQFVVRPRDQIVAQGR 331
Query: 124 RTRFLVEIISSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXX 175
F E + + V W + + LL R S+ G
Sbjct: 332 TVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL---TITNIQRSDA 388
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPT 233
G + C A V G A L V + P + + A L GT L+CK G P
Sbjct: 389 GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL 448
Query: 234 PVLRWFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
PV+ W K+ D A L + GTYTC A + G S+ + V
Sbjct: 449 PVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 507
Score = 35.5 bits (78), Expect = 0.28
Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIK 246
P VE ++ +G +L CK G PTP + W+KD ++
Sbjct: 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVE 74
>AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein
protein.
Length = 1045
Score = 62.9 bits (146), Expect = 2e-09
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ D+ G R ++ ++TW N + +L +A +VR+
Sbjct: 798 PHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 857
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G + C A N G+ S S L+V+ + K P +E+L+ +G V LE
Sbjct: 858 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 917
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+G+P PV W KD+ I
Sbjct: 918 CRVIGMPPPVFYWKKDNETI 937
Score = 49.2 bits (112), Expect = 2e-05
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + D G Y A+N G ++ + L V A+E + P L +LQ+
Sbjct: 850 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNC 906
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGS-FFCXXXXXXXXXXX 175
V G R +I W + NE ER+S+ +D + + C
Sbjct: 907 GVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDA 966
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L++
Sbjct: 967 GWYTLSAKNEAGIVSCTARLDI 988
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Query: 95 EVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA-E 152
E+ +E P+G+ P F +RL+ V G+ F +I+ KV W+++ +++ + E
Sbjct: 656 EIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNE 715
Query: 153 RVSIVRDGSFFCXXXXXXXXXXX-GRWTCTAENVGGRASCSAHLNV 197
+ R+G C G +T A N GR SCS HL V
Sbjct: 716 HCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 41.1 bits (92), Expect = 0.006
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 206 PEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREI-KAGDVFALTANAEDPTSL 263
P F + L+ +TE V+ CK+VG+P P + WFKD ++I K + + + SL
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 264 ----------GTYTCEAVNCMGRAYSSSKVHV 285
G YT A N GR S + V
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 25/128 (19%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANA 257
P F + L+ L +G V EC+V G P+P + W+++ I+ F + A
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 258 EDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGR--ASREGSL-----KPNSS 300
E+ +L G +TC A N G S +++HV G S GSL N +
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLA 279
Query: 301 GLSPEPPP 308
+ P+P P
Sbjct: 280 AIEPQPSP 287
Score = 38.7 bits (86), Expect = 0.031
Identities = 39/183 (21%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPV 235
R T ++ GR+ + + + RP F++ ++ +G + L+CKV G+P P
Sbjct: 769 RLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPE 828
Query: 236 LRWFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L W + + + + V +L + GTY C A N G+ S ++ V
Sbjct: 829 LTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV 888
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + ++ P+ +L++ V P L C+++ P P V ++ K
Sbjct: 889 VAKEVKKA--------------PVILEKLQNCGVPEGHPVRLECRVIGMPPP--VFYWKK 932
Query: 346 EGK 348
+ +
Sbjct: 933 DNE 935
Score = 34.7 bits (76), Expect = 0.50
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 8/98 (8%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRN--------ERRLLEAERVSIVRD 159
P F + LQ+L+ G F + + KV WYR + R+L+ + S+
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TCTA N G S A L+V
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 33.1 bits (72), Expect = 1.5
Identities = 16/63 (25%), Positives = 32/63 (50%)
Query: 241 DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
D ++AG++ +LT G Y+C A N G +S+++++ G +S + PN
Sbjct: 39 DIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKE 98
Query: 301 GLS 303
++
Sbjct: 99 EMN 101
Score = 32.3 bits (70), Expect = 2.7
Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 117 LTVKVGTRTRF-LVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
LTV+V T + L + ++ WY + L + + IV+ G+
Sbjct: 2 LTVQVKTSSAIELPDSLAFLWIIPMWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDT 61
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
GR++C A N+ G S SA + +
Sbjct: 62 GRYSCFASNIYGTDSTSAEIYI 83
Score = 32.3 bits (70), Expect = 2.7
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+ G L + A+ D G YTL A N AG + RL++ A+ PP +R
Sbjct: 949 DTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQ-IPPPMSVRPSGS 1007
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV 154
+ ++ + SS E + + + R ++E++ +
Sbjct: 1008 RYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL 1045
Score = 31.5 bits (68), Expect = 4.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 58 EAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+AG + LT++ A DTG Y+ ASN G+D+ + + S E P
Sbjct: 44 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDP 95
>AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein
protein.
Length = 1320
Score = 62.9 bits (146), Expect = 2e-09
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ D+ G R ++ ++TW N + +L +A +VR+
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G + C A N G+ S S L+V+ + K P +E+L+ +G V LE
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+G+P PV W KD+ I
Sbjct: 1193 CRVIGMPPPVFYWKKDNETI 1212
Score = 58.8 bits (136), Expect = 3e-08
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 10/108 (9%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSRE---------IKAGDVFALTA 255
P F ++LR+ +GT V L+C VVG+P P +RW+ + +E ++AG++ +LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
G Y+C A N G +S+++++ G +S + PN ++
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMN 376
Score = 54.0 bits (124), Expect = 8e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Query: 81 ASNAAGSDTARVRLEVSAE-ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKV 139
AS AAG DT S E P G+ PP F ++L+ V GTR + ++ +V
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPLGQ-PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQV 300
Query: 140 TWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
WY + L + + IV+ G+ GR++C A N+ G S SA + +
Sbjct: 301 RWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 49.2 bits (112), Expect = 2e-05
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + D G Y A+N G ++ + L V A+E + P L +LQ+
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNC 1181
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGS-FFCXXXXXXXXXXX 175
V G R +I W + NE ER+S+ +D + + C
Sbjct: 1182 GVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDA 1241
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L++
Sbjct: 1242 GWYTLSAKNEAGIVSCTARLDI 1263
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Query: 95 EVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA-E 152
E+ +E P+G+ P F +RL+ V G+ F +I+ KV W+++ +++ + E
Sbjct: 931 EIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNE 990
Query: 153 RVSIVRDGSFFCXXXXXXXXXXX-GRWTCTAENVGGRASCSAHLNV 197
+ R+G C G +T A N GR SCS HL V
Sbjct: 991 HCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 41.1 bits (92), Expect = 0.006
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 206 PEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREI-KAGDVFALTANAEDPTSL 263
P F + L+ +TE V+ CK+VG+P P + WFKD ++I K + + + SL
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 264 ----------GTYTCEAVNCMGRAYSSSKVHV 285
G YT A N GR S + V
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 40.7 bits (91), Expect = 0.008
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 25/128 (19%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALT-------ANA 257
P F + L+ L +G V EC+V G P+P + W+++ I+ F ++ A
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEP 494
Query: 258 EDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGR--ASREGSL-----KPNSS 300
E+ +L G +TC A N G S +++HV G S GSL N +
Sbjct: 495 EEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLA 554
Query: 301 GLSPEPPP 308
+ P+P P
Sbjct: 555 AIEPQPSP 562
Score = 38.7 bits (86), Expect = 0.031
Identities = 39/183 (21%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPV 235
R T ++ GR+ + + + RP F++ ++ +G + L+CKV G+P P
Sbjct: 1044 RLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPE 1103
Query: 236 LRWFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L W + + + + V +L + GTY C A N G+ S ++ V
Sbjct: 1104 LTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV 1163
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + ++ P+ +L++ V P L C+++ P P V ++ K
Sbjct: 1164 VAKEVKKA--------------PVILEKLQNCGVPEGHPVRLECRVIGMPPP--VFYWKK 1207
Query: 346 EGK 348
+ +
Sbjct: 1208 DNE 1210
Score = 32.3 bits (70), Expect = 2.7
Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 8/98 (8%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRN--------ERRLLEAERVSIVRD 159
P F + LQ+L+ G F + + KV WYR + R+ + + S+
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEP 494
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TCTA N G S A L+V
Sbjct: 495 EEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHV 532
Score = 32.3 bits (70), Expect = 2.7
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+ G L + A+ D G YTL A N AG + RL++ A+ PP +R
Sbjct: 1224 DTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQ-IPPPMSVRPSGS 1282
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV 154
+ ++ + SS E + + + R ++E++ +
Sbjct: 1283 RYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL 1320
Score = 31.5 bits (68), Expect = 4.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 58 EAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+AG + LT++ A DTG Y+ ASN G+D+ + + S E P
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDP 370
>AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1320
Score = 62.9 bits (146), Expect = 2e-09
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ D+ G R ++ ++TW N + +L +A +VR+
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G + C A N G+ S S L+V+ + K P +E+L+ +G V LE
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+G+P PV W KD+ I
Sbjct: 1193 CRVIGMPPPVFYWKKDNETI 1212
Score = 58.8 bits (136), Expect = 3e-08
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 10/108 (9%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSRE---------IKAGDVFALTA 255
P F ++LR+ +GT V L+C VVG+P P +RW+ + +E ++AG++ +LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
G Y+C A N G +S+++++ G +S + PN ++
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMN 376
Score = 54.0 bits (124), Expect = 8e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Query: 81 ASNAAGSDTARVRLEVSAE-ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKV 139
AS AAG DT S E P G+ PP F ++L+ V GTR + ++ +V
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPLGQ-PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQV 300
Query: 140 TWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
WY + L + + IV+ G+ GR++C A N+ G S SA + +
Sbjct: 301 RWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 49.2 bits (112), Expect = 2e-05
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + D G Y A+N G ++ + L V A+E + P L +LQ+
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNC 1181
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGS-FFCXXXXXXXXXXX 175
V G R +I W + NE ER+S+ +D + + C
Sbjct: 1182 GVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDA 1241
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L++
Sbjct: 1242 GWYTLSAKNEAGIVSCTARLDI 1263
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Query: 95 EVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA-E 152
E+ +E P+G+ P F +RL+ V G+ F +I+ KV W+++ +++ + E
Sbjct: 931 EIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNE 990
Query: 153 RVSIVRDGSFFCXXXXXXXXXXX-GRWTCTAENVGGRASCSAHLNV 197
+ R+G C G +T A N GR SCS HL V
Sbjct: 991 HCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 41.1 bits (92), Expect = 0.006
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 206 PEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREI-KAGDVFALTANAEDPTSL 263
P F + L+ +TE V+ CK+VG+P P + WFKD ++I K + + + SL
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 264 ----------GTYTCEAVNCMGRAYSSSKVHV 285
G YT A N GR S + V
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 25/128 (19%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANA 257
P F + L+ L +G V EC+V G P+P + W+++ I+ F + A
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 258 EDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGR--ASREGSL-----KPNSS 300
E+ +L G +TC A N G S +++HV G S GSL N +
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLA 554
Query: 301 GLSPEPPP 308
+ P+P P
Sbjct: 555 AIEPQPSP 562
Score = 38.7 bits (86), Expect = 0.031
Identities = 39/183 (21%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPV 235
R T ++ GR+ + + + RP F++ ++ +G + L+CKV G+P P
Sbjct: 1044 RLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPE 1103
Query: 236 LRWFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L W + + + + V +L + GTY C A N G+ S ++ V
Sbjct: 1104 LTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV 1163
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + ++ P+ +L++ V P L C+++ P P V ++ K
Sbjct: 1164 VAKEVKKA--------------PVILEKLQNCGVPEGHPVRLECRVIGMPPP--VFYWKK 1207
Query: 346 EGK 348
+ +
Sbjct: 1208 DNE 1210
Score = 34.7 bits (76), Expect = 0.50
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 8/98 (8%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRN--------ERRLLEAERVSIVRD 159
P F + LQ+L+ G F + + KV WYR + R+L+ + S+
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TCTA N G S A L+V
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 32.3 bits (70), Expect = 2.7
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+ G L + A+ D G YTL A N AG + RL++ A+ PP +R
Sbjct: 1224 DTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQ-IPPPMSVRPSGS 1282
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV 154
+ ++ + SS E + + + R ++E++ +
Sbjct: 1283 RYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL 1320
Score = 31.5 bits (68), Expect = 4.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 58 EAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+AG + LT++ A DTG Y+ ASN G+D+ + + S E P
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDP 370
>AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1045
Score = 62.9 bits (146), Expect = 2e-09
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ D+ G R ++ ++TW N + +L +A +VR+
Sbjct: 798 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 857
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G + C A N G+ S S L+V+ + K P +E+L+ +G V LE
Sbjct: 858 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 917
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+G+P PV W KD+ I
Sbjct: 918 CRVIGMPPPVFYWKKDNETI 937
Score = 49.2 bits (112), Expect = 2e-05
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + D G Y A+N G ++ + L V A+E + P L +LQ+
Sbjct: 850 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNC 906
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGS-FFCXXXXXXXXXXX 175
V G R +I W + NE ER+S+ +D + + C
Sbjct: 907 GVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDA 966
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L++
Sbjct: 967 GWYTLSAKNEAGIVSCTARLDI 988
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Query: 95 EVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA-E 152
E+ +E P+G+ P F +RL+ V G+ F +I+ KV W+++ +++ + E
Sbjct: 656 EIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNE 715
Query: 153 RVSIVRDGSFFCXXXXXXXXXXX-GRWTCTAENVGGRASCSAHLNV 197
+ R+G C G +T A N GR SCS HL V
Sbjct: 716 HCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 41.1 bits (92), Expect = 0.006
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 206 PEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREI-KAGDVFALTANAEDPTSL 263
P F + L+ +TE V+ CK+VG+P P + WFKD ++I K + + + SL
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 264 ----------GTYTCEAVNCMGRAYSSSKVHV 285
G YT A N GR S + V
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 25/128 (19%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANA 257
P F + L+ L +G V EC+V G P+P + W+++ I+ F + A
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 258 EDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGR--ASREGSL-----KPNSS 300
E+ +L G +TC A N G S +++HV G S GSL N +
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLA 279
Query: 301 GLSPEPPP 308
+ P+P P
Sbjct: 280 AIEPQPSP 287
Score = 38.7 bits (86), Expect = 0.031
Identities = 39/183 (21%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPV 235
R T ++ GR+ + + + RP F++ ++ +G + L+CKV G+P P
Sbjct: 769 RLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPE 828
Query: 236 LRWFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L W + + + + V +L + GTY C A N G+ S ++ V
Sbjct: 829 LTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV 888
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + ++ P+ +L++ V P L C+++ P P V ++ K
Sbjct: 889 VAKEVKKA--------------PVILEKLQNCGVPEGHPVRLECRVIGMPPP--VFYWKK 932
Query: 346 EGK 348
+ +
Sbjct: 933 DNE 935
Score = 34.7 bits (76), Expect = 0.50
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 8/98 (8%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRN--------ERRLLEAERVSIVRD 159
P F + LQ+L+ G F + + KV WYR + R+L+ + S+
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TCTA N G S A L+V
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 33.1 bits (72), Expect = 1.5
Identities = 16/63 (25%), Positives = 32/63 (50%)
Query: 241 DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
D ++AG++ +LT G Y+C A N G +S+++++ G +S + PN
Sbjct: 39 DIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKE 98
Query: 301 GLS 303
++
Sbjct: 99 EMN 101
Score = 32.3 bits (70), Expect = 2.7
Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 117 LTVKVGTRTRF-LVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
LTV+V T + L + ++ WY + L + + IV+ G+
Sbjct: 2 LTVQVKTSSAIELPDSLAFLWIIPMWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDT 61
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
GR++C A N+ G S SA + +
Sbjct: 62 GRYSCFASNIYGTDSTSAEIYI 83
Score = 32.3 bits (70), Expect = 2.7
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+ G L + A+ D G YTL A N AG + RL++ A+ PP +R
Sbjct: 949 DTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQ-IPPPMSVRPSGS 1007
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV 154
+ ++ + SS E + + + R ++E++ +
Sbjct: 1008 RYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL 1045
Score = 31.5 bits (68), Expect = 4.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 58 EAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+AG + LT++ A DTG Y+ ASN G+D+ + + S E P
Sbjct: 44 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDP 95
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 62.9 bits (146), Expect = 2e-09
Identities = 56/193 (29%), Positives = 81/193 (41%), Gaps = 16/193 (8%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
VST+ G +L ++ A D G Y A N+AGS + RL V PP
Sbjct: 123 VSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQV--------PPVIENG 174
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXX 172
L DL+ G+ + S E +TW ++ + + AE + +I G
Sbjct: 175 LPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDA 234
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVP 232
G +TCTAEN GRA HL +LV + LR L ++ + L C G P
Sbjct: 235 ---GTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLR--LGDR--LWLRCAARGSP 287
Query: 233 TPVLRWFKDSREI 245
TP + W + R +
Sbjct: 288 TPRIGWTVNDRPV 300
Score = 58.0 bits (134), Expect = 5e-08
Identities = 64/243 (26%), Positives = 92/243 (37%), Gaps = 24/243 (9%)
Query: 43 SRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESP 102
S+AGA L R + L + A G YT A N+AG V L V A SP
Sbjct: 22 SKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQA--SP 79
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
+ P+ +R + + V + E +TW + + ++ G
Sbjct: 80 VVKPLPSVVRAVAEEEVLLPC------EASGIPRPTITWQKEGLNVATGVSTQVLPGGQL 133
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV 222
G + C A+N G A L V VP P L L T +G+
Sbjct: 134 ---RIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP-----PVIENGLPDLSTTEGSH 185
Query: 223 S-LECKVVGVPTPVLRWFKDSREIKAGD-VFALTANAE------DPTSLGTYTCEAVNCM 274
+ L CK G P P + W KD + + + F + + E + GTYTC A N +
Sbjct: 186 AFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAV 245
Query: 275 GRA 277
GRA
Sbjct: 246 GRA 248
Score = 45.2 bits (102), Expect = 4e-04
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
GR+TC+A N G A L V K V +RA+ E+ V L C+ G+P P
Sbjct: 54 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSV--VRAVAEEE--VLLPCEASGIPRPT 109
Query: 236 LRWFKDSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+ W K+ + G + + P G Y C A N G A +++ V
Sbjct: 110 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 165
Score = 31.9 bits (69), Expect = 3.5
Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKA-GDVF------ALTANAEDPTSLGTYTCEAVNCM 274
V L C G+P P + W K ++ A G + AL P G YTC A N
Sbjct: 5 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSA 64
Query: 275 GRAY 278
G A+
Sbjct: 65 GVAH 68
>AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.
Length = 1320
Score = 62.9 bits (146), Expect = 2e-09
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ D+ G R ++ ++TW N + +L +A +VR+
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G + C A N G+ S S L+V+ + K P +E+L+ +G V LE
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+G+P PV W KD+ I
Sbjct: 1193 CRVIGMPPPVFYWKKDNETI 1212
Score = 58.8 bits (136), Expect = 3e-08
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 10/108 (9%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSRE---------IKAGDVFALTA 255
P F ++LR+ +GT V L+C VVG+P P +RW+ + +E ++AG++ +LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
G Y+C A N G +S+++++ G +S + PN ++
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMN 376
Score = 54.0 bits (124), Expect = 8e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Query: 81 ASNAAGSDTARVRLEVSAE-ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKV 139
AS AAG DT S E P G+ PP F ++L+ V GTR + ++ +V
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPLGQ-PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQV 300
Query: 140 TWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
WY + L + + IV+ G+ GR++C A N+ G S SA + +
Sbjct: 301 RWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 49.2 bits (112), Expect = 2e-05
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + D G Y A+N G ++ + L V A+E + P L +LQ+
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNC 1181
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGS-FFCXXXXXXXXXXX 175
V G R +I W + NE ER+S+ +D + + C
Sbjct: 1182 GVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDA 1241
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L++
Sbjct: 1242 GWYTLSAKNEAGIVSCTARLDI 1263
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Query: 95 EVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA-E 152
E+ +E P+G+ P F +RL+ V G+ F +I+ KV W+++ +++ + E
Sbjct: 931 EIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNE 990
Query: 153 RVSIVRDGSFFCXXXXXXXXXXX-GRWTCTAENVGGRASCSAHLNV 197
+ R+G C G +T A N GR SCS HL V
Sbjct: 991 HCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 41.1 bits (92), Expect = 0.006
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 206 PEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREI-KAGDVFALTANAEDPTSL 263
P F + L+ +TE V+ CK+VG+P P + WFKD ++I K + + + SL
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 264 ----------GTYTCEAVNCMGRAYSSSKVHV 285
G YT A N GR S + V
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 25/128 (19%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANA 257
P F + L+ L +G V EC+V G P+P + W+++ I+ F + A
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 258 EDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGR--ASREGSL-----KPNSS 300
E+ +L G +TC A N G S +++HV G S GSL N +
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLA 554
Query: 301 GLSPEPPP 308
+ P+P P
Sbjct: 555 AIEPQPSP 562
Score = 38.7 bits (86), Expect = 0.031
Identities = 39/183 (21%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPV 235
R T ++ GR+ + + + RP F++ ++ +G + L+CKV G+P P
Sbjct: 1044 RLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPE 1103
Query: 236 LRWFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L W + + + + V +L + GTY C A N G+ S ++ V
Sbjct: 1104 LTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV 1163
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + ++ P+ +L++ V P L C+++ P P V ++ K
Sbjct: 1164 VAKEVKKA--------------PVILEKLQNCGVPEGHPVRLECRVIGMPPP--VFYWKK 1207
Query: 346 EGK 348
+ +
Sbjct: 1208 DNE 1210
Score = 34.7 bits (76), Expect = 0.50
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 8/98 (8%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRN--------ERRLLEAERVSIVRD 159
P F + LQ+L+ G F + + KV WYR + R+L+ + S+
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TCTA N G S A L+V
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 32.3 bits (70), Expect = 2.7
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+ G L + A+ D G YTL A N AG + RL++ A+ PP +R
Sbjct: 1224 DTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQ-IPPPMSVRPSGS 1282
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV 154
+ ++ + SS E + + + R ++E++ +
Sbjct: 1283 RYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL 1320
Score = 31.5 bits (68), Expect = 4.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 58 EAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+AG + LT++ A DTG Y+ ASN G+D+ + + S E P
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDP 370
>AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein
protein.
Length = 1391
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 2/140 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-EAERVSIVRDGSFFCXX 166
P FL+ D+ G R ++ ++TW N + +L +A +VR+
Sbjct: 1144 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLL 1203
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G + C A N G+ S S L+V+ + K P +E+L+ +G V LE
Sbjct: 1204 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1263
Query: 226 CKVVGVPTPVLRWFKDSREI 245
C+V+G+P PV W KD+ I
Sbjct: 1264 CRVIGMPPPVFYWKKDNETI 1283
Score = 58.8 bits (136), Expect = 3e-08
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 10/108 (9%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSRE---------IKAGDVFALTA 255
P F ++LR+ +GT V L+C VVG+P P +RW+ + +E ++AG++ +LT
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 399
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
G Y+C A N G +S+++++ G +S + PN ++
Sbjct: 400 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMN 447
Score = 54.0 bits (124), Expect = 8e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Query: 81 ASNAAGSDTARVRLEVSAE-ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKV 139
AS AAG DT S E P G+ PP F ++L+ V GTR + ++ +V
Sbjct: 313 ASEAAGGDTTPGSSPSSLYYEEPLGQ-PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQV 371
Query: 140 TWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
WY + L + + IV+ G+ GR++C A N+ G S SA + +
Sbjct: 372 RWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429
Score = 50.8 bits (116), Expect = 7e-06
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 3/106 (2%)
Query: 95 EVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA-E 152
E+ +E P+G+ P F +RL+ V G+ F +I+ KV W+++ +++ + E
Sbjct: 1002 EIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNE 1061
Query: 153 RVSIVRDGSFFCXXXXXXXXXXX-GRWTCTAENVGGRASCSAHLNV 197
R + R+G C G +T A N GR SCS HL V
Sbjct: 1062 RCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1107
Score = 49.2 bits (112), Expect = 2e-05
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 5/142 (3%)
Query: 58 EAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDL 117
E G L + D G Y A+N G ++ + L V A+E + P L +LQ+
Sbjct: 1196 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNC 1252
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDGS-FFCXXXXXXXXXXX 175
V G R +I W + NE ER+S+ +D + + C
Sbjct: 1253 GVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDA 1312
Query: 176 GRWTCTAENVGGRASCSAHLNV 197
G +T +A+N G SC+A L++
Sbjct: 1313 GWYTLSAKNEAGIVSCTARLDI 1334
Score = 41.1 bits (92), Expect = 0.006
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 206 PEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREI-KAGDVFALTANAEDPTSL 263
P F + L+ +TE V+ CK+VG+P P + WFKD ++I K + + + SL
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSL 1075
Query: 264 ----------GTYTCEAVNCMGRAYSSSKVHV 285
G YT A N GR S + V
Sbjct: 1076 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1107
Score = 39.9 bits (89), Expect = 0.013
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 25/128 (19%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL-------TANA 257
P F + L+ L +G V EC+V G P+P + W+++ I+ F + A
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565
Query: 258 EDPTSL----------GTYTCEAVNCMGRAYSSSKVHVVGR--ASREGSL-----KPNSS 300
E+ +L G +TC A N G S +++HV G S GSL N +
Sbjct: 566 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLA 625
Query: 301 GLSPEPPP 308
+ P+P P
Sbjct: 626 AIEPQPSP 633
Score = 38.7 bits (86), Expect = 0.031
Identities = 39/183 (21%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPV 235
R T ++ GR+ + + + RP F++ ++ +G + L+CKV G+P P
Sbjct: 1115 RLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPE 1174
Query: 236 LRWFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
L W + + + + V +L + GTY C A N G+ S ++ V
Sbjct: 1175 LTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV 1234
Query: 286 VGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNK 345
V + ++ P+ +L++ V P L C+++ P P V ++ K
Sbjct: 1235 VAKEVKKA--------------PVILEKLQNCGVPEGHPVRLECRVIGMPPP--VFYWKK 1278
Query: 346 EGK 348
+ +
Sbjct: 1279 DNE 1281
Score = 34.7 bits (76), Expect = 0.50
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 8/98 (8%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRN--------ERRLLEAERVSIVRD 159
P F + LQ+L+ G F + + KV WYR + R+L+ + S+
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TCTA N G S A L+V
Sbjct: 566 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 603
Score = 32.3 bits (70), Expect = 2.7
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+ G L + A+ D G YTL A N AG + RL++ A+ PP +R
Sbjct: 1295 DTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQ-IPPPMSVRPSGS 1353
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV 154
+ ++ + SS E + + + R ++E++ +
Sbjct: 1354 RYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL 1391
Score = 31.5 bits (68), Expect = 4.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 58 EAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+AG + LT++ A DTG Y+ ASN G+D+ + + S E P
Sbjct: 390 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDP 441
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 62.1 bits (144), Expect = 3e-09
Identities = 61/244 (25%), Positives = 91/244 (37%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S + GD G+Y A N A S T EV P FL+R ++ G
Sbjct: 197 LQISRLQPGDIGIYRCSARNPASSRTGN-EAEVRILSDPGLHRQLYFLQRPSNVVAIEGK 255
Query: 124 RTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
+ TW R E + L +++ S++ + G +TC
Sbjct: 256 DAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDS---GMYTCVV 312
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGTVSLECKVVGVPTPVLRWFKD 241
S SA L VLVP P F+ L E + EC V G P P + W K+
Sbjct: 313 TYKNENISASAELTVLVP-----PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKN 367
Query: 242 SREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
+ D F + + + G Y C A N G A +S+++ V A S+
Sbjct: 368 GDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSV 427
Query: 296 KPNS 299
P++
Sbjct: 428 LPSA 431
Score = 40.3 bits (90), Expect = 0.010
Identities = 51/211 (24%), Positives = 86/211 (40%), Gaps = 26/211 (12%)
Query: 73 DTGVYTLQAS-NAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEI 131
D G+Y +AS +GS +R +A+ + +G P FL + + +T +G E+
Sbjct: 111 DEGLYQCEASLGDSGSIISR-----TAKVAVAG--PLRFLSQTESVTAFMGDTVLLKCEV 163
Query: 132 ISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAEN-VGG 187
I + W +N++ L RV ++ G+ G + C+A N
Sbjct: 164 IGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGAL---QISRLQPGDIGIYRCSARNPASS 220
Query: 188 RASCSAHLNVLV-PKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREI 245
R A + +L P +++ F++ ++ +G LEC V G P P W + I
Sbjct: 221 RTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVI 280
Query: 246 K--------AGDVFALTANAEDPTSLGTYTC 268
+ G L +N D S G YTC
Sbjct: 281 QLRSKKYSLLGGSNLLISNVTDDDS-GMYTC 310
Score = 34.7 bits (76), Expect = 0.50
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 11/90 (12%)
Query: 208 FVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIK--AGD--VFALTANA----- 257
F+ + ++ G TV L+C+V+G P P + W K+ +++ GD V L + A
Sbjct: 142 FLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISR 201
Query: 258 EDPTSLGTYTCEAVN-CMGRAYSSSKVHVV 286
P +G Y C A N R + ++V ++
Sbjct: 202 LQPGDIGIYRCSARNPASSRTGNEAEVRIL 231
Score = 34.7 bits (76), Expect = 0.50
Identities = 35/142 (24%), Positives = 51/142 (35%), Gaps = 13/142 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +S D+G+YT + + +A L V PP FL +L
Sbjct: 291 GGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLV--------PPWFLNHPSNLYA 342
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
F + V W +N ++ ++ IV + G +
Sbjct: 343 YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNL---RILGVVKSDEGFYQ 399
Query: 180 CTAENVGGRASCSAHLNVLVPK 201
C AEN G A SA L +VPK
Sbjct: 400 CVAENEAGNAQTSAQL--IVPK 419
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 62.1 bits (144), Expect = 3e-09
Identities = 61/244 (25%), Positives = 91/244 (37%), Gaps = 17/244 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S + GD G+Y A N A S T EV P FL+R ++ G
Sbjct: 197 LQISRLQPGDIGIYRCSARNPASSRTGN-EAEVRILSDPGLHRQLYFLQRPSNVVAIEGK 255
Query: 124 RTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
+ TW R E + L +++ S++ + G +TC
Sbjct: 256 DAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDS---GMYTCVV 312
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGTVSLECKVVGVPTPVLRWFKD 241
S SA L VLVP P F+ L E + EC V G P P + W K+
Sbjct: 313 TYKNENISASAELTVLVP-----PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKN 367
Query: 242 SREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
+ D F + + + G Y C A N G A +S+++ V A S+
Sbjct: 368 GDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSV 427
Query: 296 KPNS 299
P++
Sbjct: 428 LPSA 431
Score = 40.3 bits (90), Expect = 0.010
Identities = 51/211 (24%), Positives = 86/211 (40%), Gaps = 26/211 (12%)
Query: 73 DTGVYTLQAS-NAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEI 131
D G+Y +AS +GS +R +A+ + +G P FL + + +T +G E+
Sbjct: 111 DEGLYQCEASLGDSGSIISR-----TAKVAVAG--PLRFLSQTESVTAFMGDTVLLKCEV 163
Query: 132 ISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAEN-VGG 187
I + W +N++ L RV ++ G+ G + C+A N
Sbjct: 164 IGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGAL---QISRLQPGDIGIYRCSARNPASS 220
Query: 188 RASCSAHLNVLV-PKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREI 245
R A + +L P +++ F++ ++ +G LEC V G P P W + I
Sbjct: 221 RTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVI 280
Query: 246 K--------AGDVFALTANAEDPTSLGTYTC 268
+ G L +N D S G YTC
Sbjct: 281 QLRSKKYSLLGGSNLLISNVTDDDS-GMYTC 310
Score = 34.7 bits (76), Expect = 0.50
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 11/90 (12%)
Query: 208 FVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIK--AGD--VFALTANA----- 257
F+ + ++ G TV L+C+V+G P P + W K+ +++ GD V L + A
Sbjct: 142 FLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISR 201
Query: 258 EDPTSLGTYTCEAVN-CMGRAYSSSKVHVV 286
P +G Y C A N R + ++V ++
Sbjct: 202 LQPGDIGIYRCSARNPASSRTGNEAEVRIL 231
Score = 34.7 bits (76), Expect = 0.50
Identities = 35/142 (24%), Positives = 51/142 (35%), Gaps = 13/142 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +S D+G+YT + + +A L V PP FL +L
Sbjct: 291 GGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLV--------PPWFLNHPSNLYA 342
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
F + V W +N ++ ++ IV + G +
Sbjct: 343 YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNL---RILGVVKSDEGFYQ 399
Query: 180 CTAENVGGRASCSAHLNVLVPK 201
C AEN G A SA L +VPK
Sbjct: 400 CVAENEAGNAQTSAQL--IVPK 419
>AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein.
Length = 163
Score = 62.1 bits (144), Expect = 3e-09
Identities = 36/153 (23%), Positives = 64/153 (41%), Gaps = 3/153 (1%)
Query: 100 ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD 159
+ P P FL R + V VG +I+ + +V+W ++++ + R + +D
Sbjct: 2 DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 160 GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK--AYKRPEFVEELRALLT 217
G + G++ C A N G A + L V A + P F+ ++
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121
Query: 218 EQGT-VSLECKVVGVPTPVLRWFKDSREIKAGD 249
+G+ + C+V G P P + W KD R + D
Sbjct: 122 REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPD 154
Score = 54.8 bits (126), Expect = 4e-07
Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
RF ++ RLT+ GD+G Y +A NA G A V L+V A E+ E P FL
Sbjct: 55 RFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-EAACAEQAPHFL 113
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE 152
R + V+ G+ F + S V+W ++ RRL E +
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPD 154
Score = 45.6 bits (103), Expect = 3e-04
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 10/101 (9%)
Query: 200 PKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GD 249
P+ P F+ +A + G +L C++VG PTP + W KD + + A GD
Sbjct: 4 PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD 63
Query: 250 VFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
++ LT G Y C A N +G A+++ + V A+
Sbjct: 64 LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA 104
>AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific titin
protein.
Length = 926
Score = 62.1 bits (144), Expect = 3e-09
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P F++ + + + +G V +I + K+ W+ N L + V DG
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNV--------------LVPKAYKR------PE 207
G +TC A N G+ CSA+L + V K+ ++ P
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 208 FVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKDSREIKAGDVFALTAN--------AE 258
F++EL+ + QG ++ E VVG P P + WFK+++++ + + N
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228
Query: 259 DP--TSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
DP G Y C+A N +G + ++++ V+ + + P + +PE P F
Sbjct: 229 DPQREDSGLYICKAENMLGESTCAAELLVL-LEDTDMTDTPCKAKSTPEAPEDF 281
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 1/113 (0%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
DT + E G PP FL+ L+ + G F ++ VTW++ ++
Sbjct: 147 DTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ 206
Query: 148 LLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
L + +I+ + G + C AEN+ G ++C+A L VL+
Sbjct: 207 LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 259
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWF---------KDSREIKAGDVFALTA 255
P F++E+ G V+ L V+G+P P ++WF D + + GD +L
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASR----EGSLKPNSSGLSPEPPPI 309
G YTC A N G+ S+ K++ G + E ++ + L PP
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
F +EL+ P +V P P +V W+ KE K
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAP-TVTWF-KENK 205
>AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.
Length = 1019
Score = 62.1 bits (144), Expect = 3e-09
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P F++ + + + +G V +I + K+ W+ N L + V DG
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNV--------------LVPKAYKR------PE 207
G +TC A N G+ CSA+L + V K+ ++ P
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 208 FVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKDSREIKAGDVFALTAN--------AE 258
F++EL+ + QG ++ E VVG P P + WFK+++++ + + N
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228
Query: 259 DP--TSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIF 310
DP G Y C+A N +G + ++++ V+ + + P + +PE P F
Sbjct: 229 DPQREDSGLYICKAENMLGESTCAAELLVL-LEDTDMTDTPCKAKSTPEAPEDF 281
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 7/149 (4%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGD-TGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
D++F ++ L + T D G Y +A N +G +L V +P
Sbjct: 876 DEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAP------ 929
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXX 168
R+++ L V +G +F EI S+ + W++ R + E+++ SI
Sbjct: 930 VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEIL 989
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TC A N G SC+A L V
Sbjct: 990 RTQVVDCGEYTCKASNEYGSVSCTATLTV 1018
Score = 48.4 bits (110), Expect = 4e-05
Identities = 48/205 (23%), Positives = 75/205 (36%), Gaps = 15/205 (7%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
+S + + A V+++ AE ED P L D + G I ++ E V
Sbjct: 809 SSESGTEEVATVKIQ-EAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE--VN 865
Query: 141 WYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
WY + + E+ ++D ++ G + C A N G+ + SA L V+
Sbjct: 866 WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 925
Query: 200 PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD---------V 250
A +E L L C++ P +WFK REI D +
Sbjct: 926 RAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 983
Query: 251 FALTANAEDPTSLGTYTCEAVNCMG 275
+L G YTC+A N G
Sbjct: 984 SSLEILRTQVVDCGEYTCKASNEYG 1008
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 1/113 (0%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
DT + E G PP FL+ L+ + G F ++ VTW++ ++
Sbjct: 147 DTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ 206
Query: 148 LLEAERVSIVRD-GSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV 199
L + +I+ + G + C AEN+ G ++C+A L VL+
Sbjct: 207 LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 259
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWF---------KDSREIKAGDVFALTA 255
P F++E+ G V+ L V+G+P P ++WF D + + GD +L
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSS--KVHVVGRASR----EGSLKPNSSGLSPEPPPI 309
G YTC A N G+ S+ K++ G + E ++ + L PP
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 310 FTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
F +EL+ P +V P P +V W+ KE K
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAP-TVTWF-KENK 205
Score = 30.7 bits (66), Expect = 8.1
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
N ED G Y CEA+N G+ +S+K+ VV RA+
Sbjct: 896 NTEDHQ--GEYVCEALNDSGKTATSAKLTVVKRAA 928
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 62.1 bits (144), Expect = 3e-09
Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + D+T++ T R ++ W ++ A R+ ++ D F
Sbjct: 599 PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVF- 657
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVS 223
G ++CTA+N G S +A L VL + P V L + G TV+
Sbjct: 658 -FITDVKIDDAGVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLEDRVVSVGETVA 711
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGR 276
L+CK G P P + WFK R + + LT + + G YTCE N +G
Sbjct: 712 LQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771
Query: 277 AYSSSKVHVVGRA 289
+ S++ V+ A
Sbjct: 772 ERAHSQLSVLPAA 784
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D GVY+ A N+AGS +A L V E+PS P L+D V VG
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVL--ETPSLVVP------LEDRVVSVGETV 710
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
+ + ++TW++ +R L ER + D GR+TC N
Sbjct: 711 ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLL--VVQNVVAEDAGRYTCEMSNT 768
Query: 186 GGRASCSAHLNVL 198
G + L+VL
Sbjct: 769 LGTERAHSQLSVL 781
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 61.7 bits (143), Expect = 4e-09
Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 8/152 (5%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGS 161
E PP F L + T VG RF V I E VTWY++ +++ + + + D
Sbjct: 2914 ERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG 2973
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV----PKAYKRPEFVEELRALLT 217
+ +T A N G SC A L V + + RP F L
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAEC 3033
Query: 218 EQG-TVSLECKVVGVPTPVLRWFKDSREIKAG 248
++G +V E +V G+P P L+W KD + + G
Sbjct: 3034 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 3065
Score = 53.6 bits (123), Expect = 1e-06
Identities = 39/183 (21%), Positives = 72/183 (39%), Gaps = 3/183 (1%)
Query: 81 ASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVT 140
A N G R R +S + + + P + ++D+T K+G + +I+ +
Sbjct: 1734 AENETGLSRPR-RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK 1792
Query: 141 WYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
WYR + L+++ + + DG G +TC A N G S+ L +L
Sbjct: 1793 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQA 1851
Query: 201 KAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDP 260
P + + + T+ L +G P P + WF + ++ + + N E
Sbjct: 1852 TPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITI-ENTEHY 1910
Query: 261 TSL 263
T L
Sbjct: 1911 THL 1913
Score = 51.2 bits (117), Expect = 5e-06
Identities = 38/172 (22%), Positives = 71/172 (41%), Gaps = 8/172 (4%)
Query: 15 VRRSATLDIHPQYDRWRHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDT 74
VR T+ +HP+ HV + K + G + D ++ + G +LT+++ T D
Sbjct: 2934 VRFGVTITVHPE-----PHVTWYKSGQKIKPGDN-DKKYTFESDKGLYQLTINSVTTDDD 2987
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGED-PPTFLRRLQDLTVKVGTRTRFLVEIIS 133
YT+ A N G D+ + +L V+ P+ P F R L + + G F + +
Sbjct: 2988 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 3047
Query: 134 STECKVTWYRNERRLLEAERVSIVRDG-SFFCXXXXXXXXXXXGRWTCTAEN 184
+ W ++ + L + I+ +G ++ G + TA N
Sbjct: 3048 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
Query: 183 ENVGGRASCSAHLNVLVPKA---YKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRW 238
EN+GG + S + PK+ + P F EELR L + Q +L CKV G P P+++W
Sbjct: 2129 ENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKW 2188
Query: 239 FKDSREIKA 247
++ +EI A
Sbjct: 2189 YRQGKEIIA 2197
Score = 47.2 bits (107), Expect = 9e-05
Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 9/193 (4%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP---PTF 110
V+TEE +V G + ++ N G E+S +P + P P F
Sbjct: 2101 VTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWS---EISEPITPKSDVPIQAPHF 2157
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD--GSFFCXXXX 168
L++L V+ + + ++ + V WYR + ++ +++ G +
Sbjct: 2158 KEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIA 2217
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECK 227
+ A N GG S +A L V VP P+ +E + A+ +G VS++
Sbjct: 2218 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIP 2277
Query: 228 VVGVPTPVLRWFK 240
G P PV+ W K
Sbjct: 2278 FSGKPDPVITWQK 2290
Score = 45.2 bits (102), Expect = 4e-04
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 10/88 (11%)
Query: 206 PEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P +E++ + T+ G + L C++VG P P ++W++ +E+ G LT
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
E+ G YTC A N +G +SSK+
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKL 1847
Score = 38.3 bits (85), Expect = 0.040
Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 3/137 (2%)
Query: 65 TVSTARTGDTGVYTLQASNAAG--SDTARVRLEVSAEESPSGEDPPTFLRRLQDL-TVKV 121
TV+ GDT + + A NAAG S + V+ + + R DL T++
Sbjct: 229 TVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRA 288
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
G+ + E K+ W + ++ L E+VS+ G G++T T
Sbjct: 289 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 348
Query: 182 AENVGGRASCSAHLNVL 198
+N G + S + VL
Sbjct: 349 VKNASGTKAVSVMVKVL 365
Score = 34.3 bits (75), Expect = 0.66
Identities = 48/210 (22%), Positives = 80/210 (38%), Gaps = 13/210 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LTV T D GVYT A+N G +L + A +P P L+ + VG+
Sbjct: 1817 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA--TPQFH-PGYPLK--EKYYGAVGS 1871
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF-FCXXXXXXXXXXXGRWTCTA 182
R V I +TW+ ++ L +E ++I + G++
Sbjct: 1872 TLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 1931
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
NV G + A L+V + +P + ALL +S + + + + +
Sbjct: 1932 SNVFG--TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 1989
Query: 243 REIKAGDVFALTANAEDPTSLGTYTCEAVN 272
E K G + L ++A + TC VN
Sbjct: 1990 CEAKEGAEWQLVSSA-----ISVTTCRIVN 2014
Score = 32.7 bits (71), Expect = 2.0
Identities = 32/127 (25%), Positives = 47/127 (37%), Gaps = 10/127 (7%)
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPTPVLR 237
C A G A + V Y E E + + + G + L + G P P+ +
Sbjct: 1337 CNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICK 1396
Query: 238 WFKDSREIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA- 289
W K+ ++I + A L D GTY N G+ KV V+G
Sbjct: 1397 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPN 1456
Query: 290 SREGSLK 296
S EG L+
Sbjct: 1457 SPEGPLE 1463
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 61.7 bits (143), Expect = 4e-09
Identities = 63/245 (25%), Positives = 95/245 (38%), Gaps = 19/245 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S + GD G+Y A N A S T EV P FL+R ++ V +
Sbjct: 131 LQISRLQPGDIGIYRCSARNPASSRTGN-EAEVRILSDPGLHRQLYFLQRPSNV-VAIEG 188
Query: 124 RTRFLVEIISS-TECKVTWYRNERRL-LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
+ L +S TW R E + L +++ S++ + G +TC
Sbjct: 189 KDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDS---GMYTCV 245
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGTVSLECKVVGVPTPVLRWFK 240
S SA L VLVP P F+ L E + EC V G P P + W K
Sbjct: 246 VTYKNENISASAELTVLVP-----PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 300
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ + D F + + + G Y C A N G A +S+++ V A S
Sbjct: 301 NGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSS 360
Query: 295 LKPNS 299
+ P++
Sbjct: 361 VLPSA 365
Score = 35.5 bits (78), Expect = 0.28
Identities = 50/211 (23%), Positives = 85/211 (40%), Gaps = 26/211 (12%)
Query: 73 DTGVYTLQAS-NAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEI 131
D G+Y +AS +GS +R +A+ + +G P FL + + +T +G E+
Sbjct: 45 DEGLYQCEASLGDSGSIISR-----TAKVAVAG--PLRFLSQTESVTAFMGDTVLLKCEV 97
Query: 132 ISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAEN-VGG 187
I + W +N++ L RV ++ G+ G + C+A N
Sbjct: 98 IGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGAL---QISRLQPGDIGIYRCSARNPASS 154
Query: 188 RASCSAHLNVLV-PKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREI 245
R A + +L P +++ F++ ++ +G LE V G P P W + I
Sbjct: 155 RTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVI 214
Query: 246 K--------AGDVFALTANAEDPTSLGTYTC 268
+ G L +N D S G YTC
Sbjct: 215 QLRSKKYSLLGGSNLLISNVTDDDS-GMYTC 244
Score = 34.7 bits (76), Expect = 0.50
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 11/90 (12%)
Query: 208 FVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIK--AGD--VFALTANA----- 257
F+ + ++ G TV L+C+V+G P P + W K+ +++ GD V L + A
Sbjct: 76 FLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISR 135
Query: 258 EDPTSLGTYTCEAVN-CMGRAYSSSKVHVV 286
P +G Y C A N R + ++V ++
Sbjct: 136 LQPGDIGIYRCSARNPASSRTGNEAEVRIL 165
Score = 34.7 bits (76), Expect = 0.50
Identities = 35/142 (24%), Positives = 51/142 (35%), Gaps = 13/142 (9%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG L +S D+G+YT + + +A L V PP FL +L
Sbjct: 225 GGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLV--------PPWFLNHPSNLYA 276
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
F + V W +N ++ ++ IV + G +
Sbjct: 277 YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNL---RILGVVKSDEGFYQ 333
Query: 180 CTAENVGGRASCSAHLNVLVPK 201
C AEN G A SA L +VPK
Sbjct: 334 CVAENEAGNAQTSAQL--IVPK 353
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 61.3 bits (142), Expect = 5e-09
Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + D+T++ T R ++ W ++ A R+ ++ D F
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVF- 657
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVS 223
G ++CTA+N G S +A L VL + P V L + G TV+
Sbjct: 658 -FITDVKIDDAGVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLEDRVVSVGETVA 711
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGR 276
L+CK G P P + WFK R + + LT + + G YTCE N +G
Sbjct: 712 LQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771
Query: 277 AYSSSKVHVVGRA 289
+ S++ V+ A
Sbjct: 772 ERAHSQLSVLPAA 784
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D GVY+ A N+AGS +A L V E+PS P L+D V VG
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVL--ETPSLVVP------LEDRVVSVGETV 710
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
+ + ++TW++ +R L ER + D GR+TC N
Sbjct: 711 ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLL--VVQNVVAEDAGRYTCEMSNT 768
Query: 186 GGRASCSAHLNVL 198
G + L+VL
Sbjct: 769 LGTERAHSQLSVL 781
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 61.3 bits (142), Expect = 5e-09
Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + D+T++ T R ++ W ++ A R+ ++ D F
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVF- 657
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVS 223
G ++CTA+N G S +A L VL + P V L + G TV+
Sbjct: 658 -FITDVKIDDAGVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLEDRVVSVGETVA 711
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGR 276
L+CK G P P + WFK R + + LT + + G YTCE N +G
Sbjct: 712 LQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771
Query: 277 AYSSSKVHVVGRA 289
+ S++ V+ A
Sbjct: 772 ERAHSQLSVLPAA 784
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D GVY+ A N+AGS +A L V E+PS P L+D V VG
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVL--ETPSLVVP------LEDRVVSVGETV 710
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
+ + ++TW++ +R L ER + D GR+TC N
Sbjct: 711 ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLL--VVQNVVAEDAGRYTCEMSNT 768
Query: 186 GGRASCSAHLNVL 198
G + L+VL
Sbjct: 769 LGTERAHSQLSVL 781
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 60.9 bits (141), Expect = 7e-09
Identities = 61/249 (24%), Positives = 100/249 (40%), Gaps = 27/249 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y +A N+ G DT + R+ V A+ P +L+ + D +G+
Sbjct: 291 LQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQ--------PEWLKVISDTEADIGS 342
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ V W RN L RV ++ F G + C AE
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRF----SKLSLEDSGMYQCVAE 398
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRALL--TEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L V P+F + +R L+ G + + C+ P V+ W K
Sbjct: 399 NKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSK 454
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ + +T + + G YTC A N MG+A S+ + V R + + +
Sbjct: 455 GTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSV--RDATKIT 512
Query: 295 LKPNSSGLS 303
L P+S+ ++
Sbjct: 513 LAPSSADIN 521
Score = 33.5 bits (73), Expect = 1.1
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 205 RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPT 261
+ F E AL+ +Q V+LEC G P P ++W K + A L +
Sbjct: 242 KARFPAETYALVGQQ--VTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFE 299
Query: 262 SLGTYTCEAVNCMGR 276
GTY CEA N GR
Sbjct: 300 DEGTYECEAENSKGR 314
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 60.9 bits (141), Expect = 7e-09
Identities = 61/249 (24%), Positives = 100/249 (40%), Gaps = 27/249 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y +A N+ G DT + R+ V A+ P +L+ + D +G+
Sbjct: 291 LQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQ--------PEWLKVISDTEADIGS 342
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ V W RN L RV ++ F G + C AE
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRF----SKLSLEDSGMYQCVAE 398
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRALL--TEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L V P+F + +R L+ G + + C+ P V+ W K
Sbjct: 399 NKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSK 454
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ + +T + + G YTC A N MG+A S+ + V R + + +
Sbjct: 455 GTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSV--RDATKIT 512
Query: 295 LKPNSSGLS 303
L P+S+ ++
Sbjct: 513 LAPSSADIN 521
Score = 33.5 bits (73), Expect = 1.1
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 205 RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPT 261
+ F E AL+ +Q V+LEC G P P ++W K + A L +
Sbjct: 242 KARFPAETYALVGQQ--VTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFE 299
Query: 262 SLGTYTCEAVNCMGR 276
GTY CEA N GR
Sbjct: 300 DEGTYECEAENSKGR 314
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 60.9 bits (141), Expect = 7e-09
Identities = 61/249 (24%), Positives = 100/249 (40%), Gaps = 27/249 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y +A N+ G DT + R+ V A+ P +L+ + D +G+
Sbjct: 291 LQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQ--------PEWLKVISDTEADIGS 342
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ V W RN L RV ++ F G + C AE
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRF----SKLSLEDSGMYQCVAE 398
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRALL--TEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L V P+F + +R L+ G + + C+ P V+ W K
Sbjct: 399 NKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSK 454
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ + +T + + G YTC A N MG+A S+ + V R + + +
Sbjct: 455 GTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSV--RDATKIT 512
Query: 295 LKPNSSGLS 303
L P+S+ ++
Sbjct: 513 LAPSSADIN 521
Score = 33.5 bits (73), Expect = 1.1
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 205 RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPT 261
+ F E AL+ +Q V+LEC G P P ++W K + A L +
Sbjct: 242 KARFPAETYALVGQQ--VTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFE 299
Query: 262 SLGTYTCEAVNCMGR 276
GTY CEA N GR
Sbjct: 300 DEGTYECEAENSKGR 314
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 60.9 bits (141), Expect = 7e-09
Identities = 61/249 (24%), Positives = 100/249 (40%), Gaps = 27/249 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y +A N+ G DT + R+ V A+ P +L+ + D +G+
Sbjct: 291 LQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQ--------PEWLKVISDTEADIGS 342
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ V W RN L RV ++ F G + C AE
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRF----SKLSLEDSGMYQCVAE 398
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRALL--TEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L V P+F + +R L+ G + + C+ P V+ W K
Sbjct: 399 NKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSK 454
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ + +T + + G YTC A N MG+A S+ + V R + + +
Sbjct: 455 GTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSV--RDATKIT 512
Query: 295 LKPNSSGLS 303
L P+S+ ++
Sbjct: 513 LAPSSADIN 521
Score = 33.5 bits (73), Expect = 1.1
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 205 RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPT 261
+ F E AL+ +Q V+LEC G P P ++W K + A L +
Sbjct: 242 KARFPAETYALVGQQ--VTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFE 299
Query: 262 SLGTYTCEAVNCMGR 276
GTY CEA N GR
Sbjct: 300 DEGTYECEAENSKGR 314
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 60.5 bits (140), Expect = 9e-09
Identities = 65/288 (22%), Positives = 109/288 (37%), Gaps = 22/288 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
+ G YT A N G D RVR++V +P+ T+L + V G E
Sbjct: 2318 EEGDYTCFAENQVGKDEMRVRVKVVT--APATIRNKTYLA----VQVPYGDVVTVACEAK 2371
Query: 133 SSTECKVTWYRNERRLL--EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG--R 188
KVTW +++ +E+ I +DG+ G +TC N G R
Sbjct: 2372 GEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDS---GNYTCLVRNSAGEDR 2428
Query: 189 ASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG 248
+ H+NV PK P + +R + ++CK G+PTP + W +
Sbjct: 2429 KTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPA 2488
Query: 249 DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPP 308
+ SL + + ++ S V + E L + L P P
Sbjct: 2489 PYYGNRITVHGNGSLD------IRSLRKSDSVQLVCMARNEGGEARLIVQLTVLEPMEKP 2542
Query: 309 IFTRELEDQYVRIC-EPFTLSCQIVVPPWPRSVVWYNKEG-KVEAGER 354
IF + ++ + +L+C P P S+VW G +++G++
Sbjct: 2543 IFHDPISEKITAMAGHTISLNCSAAGTPTP-SLVWVLPNGTDLQSGQQ 2589
Score = 55.2 bits (127), Expect = 3e-07
Identities = 59/244 (24%), Positives = 93/244 (38%), Gaps = 25/244 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L++ A D GVY ASNAAG+D+ +RL V+A P +L+++++ G
Sbjct: 2010 LSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALP------PVIHQEKLENISLPPGL 2063
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAER-----VSIVRDGSFFCXXXXXXXXXXXGRW 178
++ V W + + + + + +G+ + GR+
Sbjct: 2064 SIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDS---GRY 2120
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C A N+ G A + LNV A R R + GT+ L+C G P P + W
Sbjct: 2121 ECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILW 2180
Query: 239 -----------FKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F IK L + G Y C A N +G Y KV VV
Sbjct: 2181 RLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVM 2240
Query: 288 RASR 291
+ ++
Sbjct: 2241 KPAK 2244
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/181 (25%), Positives = 74/181 (40%), Gaps = 13/181 (7%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ D+G YT N+AG D V + V+ + P P + ++++ G+
Sbjct: 2403 LLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNV-QPPKINGNPNPITTVREIAAG-GS 2460
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEA----ERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
R + +V W E +L A R+++ +GS +
Sbjct: 2461 RKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSL---DIRSLRKSDSVQLV 2517
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG--TVSLECKVVGVPTPVLR 237
C A N GG A L VL P ++P F + + +T T+SL C G PTP L
Sbjct: 2518 CMARNEGGEARLIVQLTVLEP--MEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLV 2575
Query: 238 W 238
W
Sbjct: 2576 W 2576
Score = 48.0 bits (109), Expect = 5e-05
Identities = 74/326 (22%), Positives = 121/326 (37%), Gaps = 45/326 (13%)
Query: 35 RAFILNTKSRAGASL--DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARV 92
+ F+ TK GA + + R E L + + D G Y ASN G D V
Sbjct: 1882 KPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVV 1941
Query: 93 RLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA- 151
L V+ ++ P QD+TV +G + +++W +RR+ +
Sbjct: 1942 LLSVTVQQ------PQILASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTV 1995
Query: 152 ----ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPE 207
R+++ + + G + C A N G S + L+V E
Sbjct: 1996 SPVESRITLHENRTL---SIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQE 2052
Query: 208 FVEELRALLTEQGTVSLECKVVGVPTPVLRW-FKDSREIKA-----GDVF-----ALTAN 256
+E + L ++ + C P P +RW D +I+ G++F L
Sbjct: 2053 KLENIS--LPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIR 2110
Query: 257 AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELED 316
P G Y C A N +G A + +++ V RA+ + +G SP R +
Sbjct: 2111 NLAPKDSGRYECVAANLVGSARRTVQLN-VQRAAANARI----TGTSP-------RRTD- 2157
Query: 317 QYVRICEPFTLSCQIVVPPWPRSVVW 342
VR L C PWPR ++W
Sbjct: 2158 --VRYGGTLKLDCSASGDPWPR-ILW 2180
Score = 42.3 bits (95), Expect = 0.002
Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 21/198 (10%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL-----EAERVSIVR 158
GE P + Q ++V T T F E + VTW + L +R +++
Sbjct: 1850 GEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLK 1909
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTE 218
+G+ G++ CTA N+ G L+V V + +++ L +
Sbjct: 1910 NGTLVIRKVQVQDR---GQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGD 1966
Query: 219 QGTVSLECKVVGVPTPVLRW-FKDSR----------EIKAGDVFALTANAEDPTSLGTYT 267
T+++EC G P P + W F D R I + L+ + G Y
Sbjct: 1967 --TIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYK 2024
Query: 268 CEAVNCMGRAYSSSKVHV 285
C A N G + ++HV
Sbjct: 2025 CVASNAAGADSLAIRLHV 2042
Score = 31.9 bits (69), Expect = 3.5
Identities = 36/171 (21%), Positives = 65/171 (38%), Gaps = 14/171 (8%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G Y A+N GS V+L V + + T RR V+ G +
Sbjct: 2116 DSGRYECVAANLVGSARRTVQLNVQ-RAAANARITGTSPRRTD---VRYGGTLKLDCSAS 2171
Query: 133 SSTECKVTWYRNERRLLEA-----ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG 187
++ W +R+++A R+ + +G+ G + C A N G
Sbjct: 2172 GDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDA---GDYLCVARNKVG 2228
Query: 188 RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
++V++ A + E EE + G + ++C G+P P + W
Sbjct: 2229 DDYVVLKVDVVMKPA--KIEHKEENDHKVFYGGDLKVDCVATGLPNPEISW 2277
Score = 31.9 bits (69), Expect = 3.5
Identities = 56/240 (23%), Positives = 87/240 (36%), Gaps = 31/240 (12%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S + D G Y A NAAG V L+V G P + +++ G
Sbjct: 2601 LHISGLSSVDAGAYRCVARNAAGHTERLVSLKV-------GLKPEANKQYHNLVSIINGE 2653
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE----RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + + +W LE RVS++ +G+ G +
Sbjct: 2654 TLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTL---TVREASVFDRGTYV 2710
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRW 238
C E G + S + V+ AY E + T G TV L C +G+P + W
Sbjct: 2711 CRMETEYGPSVTSIPVIVI---AYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITW 2767
Query: 239 -FKDSREIKAG-------DVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
D +KAG + F +LT G Y C A N +G ++ +HV
Sbjct: 2768 ELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHV 2827
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + DLT++ G R + ++ W ++ A R+ ++ + F
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF- 661
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G ++CTA+N G S +A L VL ++ RP L +T+ T L
Sbjct: 662 -FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRP----LLDRTVTKGETAVL 716
Query: 225 ECKVVGVPTPVLRWFKDSREI--------KAGDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+C G P P L W KD + AG+ + ++ D + G YTCE N +G
Sbjct: 717 QCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDS-DVSDAGKYTCEMSNTLGT 775
Query: 277 AYSSSKVHVV 286
+ ++ V+
Sbjct: 776 ERGNVRLSVI 785
Score = 40.3 bits (90), Expect = 0.010
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D GVY+ A N+AGS +A L V + P+FLR L D TV G
Sbjct: 670 DIGVYSCTAQNSAGSISANATLTVL--------ETPSFLRPLLDRTVTKGETAVLQCIAG 721
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S K+ W +++ L+ ER G++TC N G +
Sbjct: 722 GSPPPKLNWTKDDSPLVVTERHFFAAGNQLL--IIVDSDVSDAGKYTCEMSNTLGTERGN 779
Query: 193 AHLNVLVPKAYKRPE 207
L+V+ P+
Sbjct: 780 VRLSVIPTPTCDSPQ 794
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + DLT++ G R + ++ W ++ A R+ ++ + F
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF- 661
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G ++CTA+N G S +A L VL ++ RP L +T+ T L
Sbjct: 662 -FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRP----LLDRTVTKGETAVL 716
Query: 225 ECKVVGVPTPVLRWFKDSREI--------KAGDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+C G P P L W KD + AG+ + ++ D + G YTCE N +G
Sbjct: 717 QCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDS-DVSDAGKYTCEMSNTLGT 775
Query: 277 AYSSSKVHVV 286
+ ++ V+
Sbjct: 776 ERGNVRLSVI 785
Score = 40.3 bits (90), Expect = 0.010
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D GVY+ A N+AGS +A L V + P+FLR L D TV G
Sbjct: 670 DIGVYSCTAQNSAGSISANATLTVL--------ETPSFLRPLLDRTVTKGETAVLQCIAG 721
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S K+ W +++ L+ ER G++TC N G +
Sbjct: 722 GSPPPKLNWTKDDSPLVVTERHFFAAGNQLL--IIVDSDVSDAGKYTCEMSNTLGTERGN 779
Query: 193 AHLNVLVPKAYKRPE 207
L+V+ P+
Sbjct: 780 VRLSVIPTPTCDSPQ 794
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + DLT++ G R + ++ W ++ A R+ ++ + F
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF- 661
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G ++CTA+N G S +A L VL ++ RP L +T+ T L
Sbjct: 662 -FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRP----LLDRTVTKGETAVL 716
Query: 225 ECKVVGVPTPVLRWFKDSREI--------KAGDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+C G P P L W KD + AG+ + ++ D + G YTCE N +G
Sbjct: 717 QCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDS-DVSDAGKYTCEMSNTLGT 775
Query: 277 AYSSSKVHVV 286
+ ++ V+
Sbjct: 776 ERGNVRLSVI 785
Score = 40.3 bits (90), Expect = 0.010
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D GVY+ A N+AGS +A L V + P+FLR L D TV G
Sbjct: 670 DIGVYSCTAQNSAGSISANATLTVL--------ETPSFLRPLLDRTVTKGETAVLQCIAG 721
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S K+ W +++ L+ ER G++TC N G +
Sbjct: 722 GSPPPKLNWTKDDSPLVVTERHFFAAGNQLL--IIVDSDVSDAGKYTCEMSNTLGTERGN 779
Query: 193 AHLNVLVPKAYKRPE 207
L+V+ P+
Sbjct: 780 VRLSVIPTPTCDSPQ 794
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + DLT++ G R + ++ W ++ A R+ ++ + F
Sbjct: 543 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF- 601
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G ++CTA+N G S +A L VL ++ RP L +T+ T L
Sbjct: 602 -FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRP----LLDRTVTKGETAVL 656
Query: 225 ECKVVGVPTPVLRWFKDSREI--------KAGDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+C G P P L W KD + AG+ + ++ D + G YTCE N +G
Sbjct: 657 QCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDS-DVSDAGKYTCEMSNTLGT 715
Query: 277 AYSSSKVHVV 286
+ ++ V+
Sbjct: 716 ERGNVRLSVI 725
Score = 40.3 bits (90), Expect = 0.010
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D GVY+ A N+AGS +A L V + P+FLR L D TV G
Sbjct: 610 DIGVYSCTAQNSAGSISANATLTVL--------ETPSFLRPLLDRTVTKGETAVLQCIAG 661
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S K+ W +++ L+ ER G++TC N G +
Sbjct: 662 GSPPPKLNWTKDDSPLVVTERHFFAAGNQLL--IIVDSDVSDAGKYTCEMSNTLGTERGN 719
Query: 193 AHLNVLVPKAYKRPE 207
L+V+ P+
Sbjct: 720 VRLSVIPTPTCDSPQ 734
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + DLT++ G R + ++ W ++ A R+ ++ + F
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF- 661
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G ++CTA+N G S +A L VL ++ RP L +T+ T L
Sbjct: 662 -FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRP----LLDRTVTKGETAVL 716
Query: 225 ECKVVGVPTPVLRWFKDSREI--------KAGDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+C G P P L W KD + AG+ + ++ D + G YTCE N +G
Sbjct: 717 QCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDS-DVSDAGKYTCEMSNTLGT 775
Query: 277 AYSSSKVHVV 286
+ ++ V+
Sbjct: 776 ERGNVRLSVI 785
Score = 40.3 bits (90), Expect = 0.010
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D GVY+ A N+AGS +A L V + P+FLR L D TV G
Sbjct: 670 DIGVYSCTAQNSAGSISANATLTVL--------ETPSFLRPLLDRTVTKGETAVLQCIAG 721
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S K+ W +++ L+ ER G++TC N G +
Sbjct: 722 GSPPPKLNWTKDDSPLVVTERHFFAAGNQLL--IIVDSDVSDAGKYTCEMSNTLGTERGN 779
Query: 193 AHLNVLVPKAYKRPE 207
L+V+ P+
Sbjct: 780 VRLSVIPTPTCDSPQ 794
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens
cDNA FLJ90440 fis, clone NT2RP3000921, weakly similar to
TUMOR SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA---ERVSIVRDGSFFC 164
P+F + DLT++ G R + ++ W ++ A R+ ++ + F
Sbjct: 181 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVF- 239
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL 224
G ++CTA+N G S +A L VL ++ RP L +T+ T L
Sbjct: 240 -FIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRP----LLDRTVTKGETAVL 294
Query: 225 ECKVVGVPTPVLRWFKDSREI--------KAGDVFALTANAEDPTSLGTYTCEAVNCMGR 276
+C G P P L W KD + AG+ + ++ D + G YTCE N +G
Sbjct: 295 QCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDS-DVSDAGKYTCEMSNTLGT 353
Query: 277 AYSSSKVHVV 286
+ ++ V+
Sbjct: 354 ERGNVRLSVI 363
Score = 40.3 bits (90), Expect = 0.010
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D GVY+ A N+AGS +A L V + P+FLR L D TV G
Sbjct: 248 DIGVYSCTAQNSAGSISANATLTVL--------ETPSFLRPLLDRTVTKGETAVLQCIAG 299
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S K+ W +++ L+ ER G++TC N G +
Sbjct: 300 GSPPPKLNWTKDDSPLVVTERHFFAAGNQLL--IIVDSDVSDAGKYTCEMSNTLGTERGN 357
Query: 193 AHLNVLVPKAYKRPE 207
L+V+ P+
Sbjct: 358 VRLSVIPTPTCDSPQ 372
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 59.7 bits (138), Expect = 2e-08
Identities = 64/239 (26%), Positives = 96/239 (40%), Gaps = 33/239 (13%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G+Y ASN+AG+D L + P + +L V +G
Sbjct: 7 LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI--------EAPKLMVVQSELLVALGD 58
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T + +V W++ + L + ++ D G +TC A
Sbjct: 59 ITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDLDAGDYTCVAI 116
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRW---- 238
N GRA+ L+V P P F++E + E G+ V+L C V G P P ++W
Sbjct: 117 NEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 171
Query: 239 --------FKDSR--EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
F S +++ G +F L A D GTY CEA N G+ S + V V G
Sbjct: 172 NMPIFSRPFSVSSISQLRTGALFILNLWASDK---GTYICEAENQFGKIQSETTVTVTG 227
Score = 47.2 bits (107), Expect = 9e-05
Identities = 60/255 (23%), Positives = 98/255 (38%), Gaps = 29/255 (11%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L + +++ G L + + D G YT ASN AG++ + V P
Sbjct: 273 LQNPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL--------P 322
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXX 167
T Q L+ G + + + V W + + + + S DGS +
Sbjct: 323 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 382
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVE-----ELRALLTEQGT 221
G + CTA N G A L V V P+ + + E+ L E+
Sbjct: 383 GGEES---GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE-- 437
Query: 222 VSLECKVVGVPTPVLRWFKDSREI---KAGDVFALTAN---AEDPTS-LGTYTCEAVNCM 274
V+L C+V +P P++ W K+++ I F + + E TS G Y C A N
Sbjct: 438 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 497
Query: 275 GRAYSSSKVHVVGRA 289
G + K++V G +
Sbjct: 498 GNVTQAVKLNVHGES 512
Score = 44.8 bits (101), Expect = 5e-04
Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 21/169 (12%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTP 234
G + C A N G ++ L + + P+ + LL G ++ +ECK G+P P
Sbjct: 18 GIYGCLASNSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVMECKTSGIPPP 72
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRA-YSSSKVHVVGRASREG 293
++WFK E++ + DP LG + + Y+ ++ GRA+ +
Sbjct: 73 QVKWFKGDLELRPSTFLII-----DPL-LGLLKIQETQDLDAGDYTCVAINEAGRATGKI 126
Query: 294 SLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
+L S PP+F +E D + I TL C + P P ++ W
Sbjct: 127 TLDVGS-------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEP-TIKW 167
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 62/246 (25%), Positives = 104/246 (42%), Gaps = 17/246 (6%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSA 98
N K + S + +E+ G L + RT D VY A N+ G T +L V
Sbjct: 67 NKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR 126
Query: 99 EES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE---R 153
E+ PSG P Q L V TRT ++ S + ++TW+++ + + R
Sbjct: 127 EDQLPSGF--PNIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 183
Query: 154 VSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEEL 212
+ +R G+ G++ C A N G R S A+L V V + R +
Sbjct: 184 IKQLRSGAL---QIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMS 240
Query: 213 RALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---GTYTCE 269
++ G V++ C VG P P ++W + + ++ D + N + T + YTC
Sbjct: 241 HEIMPG-GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCV 299
Query: 270 AVNCMG 275
A++ +G
Sbjct: 300 AMSSLG 305
Score = 54.0 bits (124), Expect = 8e-07
Identities = 53/219 (24%), Positives = 89/219 (40%), Gaps = 18/219 (8%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
+ E+PP F++ +D G F+ + + +VTW + +++ +I D S
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 163 FCXXXXXXXXXXXGR--WTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ C A+N G + A L VL +P + + +L+ ++
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
T ++ C G P P + WFKD + IK AL + + T G Y
Sbjct: 147 ERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YSS + ++V V R + S+ P S + P
Sbjct: 207 CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMP 245
>AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein
protein.
Length = 584
Score = 59.3 bits (137), Expect = 2e-08
Identities = 66/290 (22%), Positives = 108/290 (37%), Gaps = 26/290 (8%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKV--GTRTRFLVE 130
+ G YT A N G D RVR++V P +R L V+V G E
Sbjct: 74 EEGDYTCFAENQVGKDEMRVRVKVVTA--------PATIRNKTCLAVQVPYGDVVTVACE 125
Query: 131 IISSTECKVTWYRNERRLL--EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG- 187
KVTW +++ +E+ I +DG+ G +TC N G
Sbjct: 126 AKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDS---GNYTCLVRNSAGE 182
Query: 188 -RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIK 246
R + H+NV PK P + +R + ++CK G+PTP + W +
Sbjct: 183 DRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVL 242
Query: 247 AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP 306
+ SL + + ++ S V + E L + L P
Sbjct: 243 PAPYYGNRITVHGNGSLD------IRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPME 296
Query: 307 PPIFTRELEDQYVRIC-EPFTLSCQIVVPPWPRSVVWYNKEG-KVEAGER 354
PIF + ++ + +L+C P P S+VW G +++G++
Sbjct: 297 KPIFHDPISEKITAMAGHTISLNCSAAGTPTP-SLVWVLPNGTDLQSGQQ 345
Score = 53.2 bits (122), Expect = 1e-06
Identities = 59/248 (23%), Positives = 99/248 (39%), Gaps = 21/248 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A+ D+G YT N+AG D V + V+ + P P + ++++ G+
Sbjct: 159 LLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNV-QPPKINGNPNPITTVREIAAG-GS 216
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEA----ERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
R + +V W E +L A R+++ +GS +
Sbjct: 217 RKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSL---DIRSLRKSDSVQLV 273
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG--TVSLECKVVGVPTPVLR 237
C A N GG A L VL P ++P F + + +T T+SL C G PTP L
Sbjct: 274 CMARNEGGEARLILQLTVLEP--MEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLV 331
Query: 238 W-FKDSREIKAGDVFALTANAEDP----TSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
W + ++++G + D + L + A C+ R ++ H S +
Sbjct: 332 WVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVAR---NAAGHTERLVSLK 388
Query: 293 GSLKPNSS 300
LKP +S
Sbjct: 389 VGLKPEAS 396
Score = 32.3 bits (70), Expect = 2.7
Identities = 56/240 (23%), Positives = 88/240 (36%), Gaps = 31/240 (12%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S + D G Y A NAAG V L+V + S + L +++ G
Sbjct: 357 LHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEASKQ-----YHNL--VSIINGE 409
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE----RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + + +W LE RVS++ +G+ G +
Sbjct: 410 TLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTL---TVREASVFDRGTYV 466
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRW 238
C E G + S + V+ AY E + T G TV L C +G+P + W
Sbjct: 467 CRMETEYGPSVTSIPVIVI---AYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITW 523
Query: 239 -FKDSREIKAG-------DVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
D +KAG + F +LT G Y C A N +G ++ +HV
Sbjct: 524 ELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHV 583
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 59.3 bits (137), Expect = 2e-08
Identities = 62/246 (25%), Positives = 104/246 (42%), Gaps = 17/246 (6%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSA 98
N K + S + +E+ G L + RT D VY A N+ G T +L V
Sbjct: 93 NKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR 152
Query: 99 EES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE---R 153
E+ PSG P Q L V TRT ++ S + ++TW+++ + + R
Sbjct: 153 EDQLPSGF--PNIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 209
Query: 154 VSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEEL 212
+ +R G+ G++ C A N G R S A+L V V + R +
Sbjct: 210 IKQLRSGAL---QIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMS 266
Query: 213 RALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---GTYTCE 269
++ G V++ C VG P P ++W + + ++ D + N + T + YTC
Sbjct: 267 HEIMPG-GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCV 325
Query: 270 AVNCMG 275
A++ +G
Sbjct: 326 AMSSLG 331
Score = 54.0 bits (124), Expect = 8e-07
Identities = 53/219 (24%), Positives = 89/219 (40%), Gaps = 18/219 (8%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
+ E+PP F++ +D G F+ + + +VTW + +++ +I D S
Sbjct: 54 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 113
Query: 163 FCXXXXXXXXXXXGR--WTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ C A+N G + A L VL +P + + +L+ ++
Sbjct: 114 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLK-VV 172
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
T ++ C G P P + WFKD + IK AL + + T G Y
Sbjct: 173 ERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYE 232
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YSS + ++V V R + S+ P S + P
Sbjct: 233 CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMP 271
>AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein.
Length = 507
Score = 58.8 bits (136), Expect = 3e-08
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 10/108 (9%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSRE---------IKAGDVFALTA 255
P F ++LR+ +GT V L+C VVG+P P +RW+ + +E ++AG++ +LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLS 303
G Y+C A N G +S+++++ G +S + PN ++
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMN 376
Score = 54.0 bits (124), Expect = 8e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Query: 81 ASNAAGSDTARVRLEVSAE-ESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKV 139
AS AAG DT S E P G+ PP F ++L+ V GTR + ++ +V
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPLGQ-PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQV 300
Query: 140 TWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
WY + L + + IV+ G+ GR++C A N+ G S SA + +
Sbjct: 301 RWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 32.7 bits (71), Expect = 2.0
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
P F + L+ L +G V EC+V G P+P + W+++ I+ F +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRI 483
Score = 31.5 bits (68), Expect = 4.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 58 EAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
+AG + LT++ A DTG Y+ ASN G+D+ + + S E P
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDP 370
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 57.6 bits (133), Expect = 6e-08
Identities = 61/251 (24%), Positives = 103/251 (41%), Gaps = 16/251 (6%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE-- 152
E+ P G PT Q L V TRT ++ S + ++TW+++ + +
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 153 -RVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKR--PEF 208
R+ +R S G++ C A N G R S A+L V + +R P F
Sbjct: 173 GRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRF 232
Query: 209 -VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---EDPTSLG 264
+ + G+V++ C VG P P ++W + ++ D + N D
Sbjct: 233 SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSA 292
Query: 265 TYTCEAVNCMG 275
YTC A++ +G
Sbjct: 293 NYTCVAMSTLG 303
Score = 51.2 bits (117), Expect = 5e-06
Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 21/195 (10%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + +++ +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSN-QRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKDS------------REIKAGDVFALTANAEDPTSLGT 265
T ++ C G P P + WFKD +++++ + AL + + G
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGK 198
Query: 266 YTCEAVNCMGRAYSS 280
Y C A N G YS+
Sbjct: 199 YECVATNSAGTRYSA 213
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 57.6 bits (133), Expect = 6e-08
Identities = 61/249 (24%), Positives = 102/249 (40%), Gaps = 16/249 (6%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE-- 152
E+ P G PT Q L V TRT ++ S + ++TW+++ + +
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 153 -RVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEF-V 209
R+ +R S G++ C A N G R S A+L V V + P F +
Sbjct: 173 GRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRV--PPRFSI 230
Query: 210 EELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---EDPTSLGTY 266
+ G+V++ C VG P P ++W + ++ D + N D Y
Sbjct: 231 PPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANY 290
Query: 267 TCEAVNCMG 275
TC A++ +G
Sbjct: 291 TCVAMSTLG 299
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/221 (23%), Positives = 88/221 (39%), Gaps = 23/221 (10%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + +++ +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSN-QRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKDS------------REIKAGDVFALTANAEDPTSLGT 265
T ++ C G P P + WFKD +++++ + AL + + G
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGK 198
Query: 266 YTCEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
Y C A N G YS+ + ++V V R S+ P + + P
Sbjct: 199 YECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMP 239
>AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing
glycosylphosphatidylinositol anchor 2 protein.
Length = 956
Score = 57.6 bits (133), Expect = 6e-08
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 10/198 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G LT+ + D G Y+ A+N G+ A+ + G T +D ++
Sbjct: 292 GGTLTIPAITSDDAGTYSCIANNNVGNP-AKKSTNIIVRALKKGRFWITPDPYHKDDNIQ 350
Query: 121 VGTRTRFL--VEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX-----X 173
+G + VE + S E +W++N R L +ER+ I +
Sbjct: 351 IGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFT 410
Query: 174 XXGRWTCTAENVGGRAS-CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGV 231
G +TC A GG S S +N+ +E L+T +G T+ L+C+V G
Sbjct: 411 DFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGK 470
Query: 232 PTPVLRWFKDSREIKAGD 249
P P++ W + +E+ D
Sbjct: 471 PKPIILWSRADKEVAMPD 488
>AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein
protein.
Length = 937
Score = 57.6 bits (133), Expect = 6e-08
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 10/198 (5%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G LT+ + D G Y+ A+N G+ A+ + G T +D ++
Sbjct: 273 GGTLTIPAITSDDAGTYSCIANNNVGNP-AKKSTNIIVRALKKGRFWITPDPYHKDDNIQ 331
Query: 121 VGTRTRFL--VEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX-----X 173
+G + VE + S E +W++N R L +ER+ I +
Sbjct: 332 IGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFT 391
Query: 174 XXGRWTCTAENVGGRAS-CSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGV 231
G +TC A GG S S +N+ +E L+T +G T+ L+C+V G
Sbjct: 392 DFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGK 451
Query: 232 PTPVLRWFKDSREIKAGD 249
P P++ W + +E+ D
Sbjct: 452 PKPIILWSRADKEVAMPD 469
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/240 (22%), Positives = 100/240 (41%), Gaps = 13/240 (5%)
Query: 54 VSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR 112
+ ++ G L + R D +Y A+N+ G +L V EE P +
Sbjct: 71 IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMG 130
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGSFFCXXXXX 169
+ K T T L + + +++W+++ + A R+ +R G+
Sbjct: 131 PQLKVVEKARTAT-MLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGAL---QIES 186
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
G++ C A N G R S A+L V V + R + ++ G+V+L C
Sbjct: 187 SEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPG-GSVNLTCVA 245
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---GTYTCEAVNCMGRAYSSSKVHV 285
VG P P ++W + E+ D + N + +++ YTC A++ +G ++++V V
Sbjct: 246 VGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTV 305
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/219 (23%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + ++ + ++R ++ DG+
Sbjct: 19 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGA 77
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 78 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 136
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 137 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 196
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YS+ + ++V V R + S+ P+S + P
Sbjct: 197 CVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP 235
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/223 (23%), Positives = 85/223 (38%), Gaps = 25/223 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+Y +A N+ G ++ R +L+V P ++ +L D + G+
Sbjct: 354 LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY--------PHWVEKLNDTQLDSGS 405
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ + W +N L RV +V G + C AE
Sbjct: 406 PLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 461
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRA--LLTEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L +L P F + +L+ ++T+ V +ECK G P P + W K
Sbjct: 462 NKYGAIYASAELKILA----SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKK 517
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRA 277
R ++ A+ + + G Y C N G A
Sbjct: 518 GDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/175 (26%), Positives = 72/175 (41%), Gaps = 17/175 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E GV L + D G+Y A N G+ A L++ A PTF
Sbjct: 437 EMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA-------PTFALNQLK 488
Query: 117 LTVKVGTRTRFLVEII--SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXX 174
T+ V ++E S + ++W + +R + E +R++I+ DGS
Sbjct: 489 KTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSL---RILNASKSD 545
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVV 229
G++ C ENV G A A L+V P R E + R LT ++ L CK +
Sbjct: 546 EGKYVCRGENVFGSAEIIASLSVKEP---TRIELTPK-RTELTVGESIVLNCKAI 596
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN G+ S L V Y P +VE+L + G+ + ECK G P P
Sbjct: 365 GIYECRAENSRGKNSFRGQLQV-----YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 419
Query: 235 VLRWFKD-------SR-EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
RW K+ SR E+ G + N D G Y C A N G Y+S+++ ++
Sbjct: 420 TYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDA---GMYQCLAENKYGAIYASAELKIL 476
Query: 287 GRA 289
A
Sbjct: 477 ASA 479
Score = 33.5 bits (73), Expect = 1.1
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 12/86 (13%)
Query: 206 PEFVEELRALL----TEQGTVSLECKVVGVPTPVLRWFKDSREIKAG--------DVFAL 253
P FV+E ++ +++ V+L C+V G P P RW ++ EI D +
Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158
Query: 254 TANAEDPTSLGTYTCEAVNCMGRAYS 279
+N + G Y C A N +G S
Sbjct: 159 ISNPSEAKDSGHYQCLATNTVGSILS 184
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/240 (22%), Positives = 100/240 (41%), Gaps = 13/240 (5%)
Query: 54 VSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR 112
+ ++ G L + R D +Y A+N+ G +L V EE P +
Sbjct: 81 IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMG 140
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGSFFCXXXXX 169
+ K T T L + + +++W+++ + A R+ +R G+
Sbjct: 141 PQLKVVEKARTAT-MLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGAL---QIES 196
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
G++ C A N G R S A+L V V + R + ++ G+V+L C
Sbjct: 197 SEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPG-GSVNLTCVA 255
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---GTYTCEAVNCMGRAYSSSKVHV 285
VG P P ++W + E+ D + N + +++ YTC A++ +G ++++V V
Sbjct: 256 VGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTV 315
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/219 (23%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + ++ + ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YS+ + ++V V R + S+ P+S + P
Sbjct: 207 CVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP 245
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/223 (23%), Positives = 85/223 (38%), Gaps = 25/223 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+Y +A N+ G ++ R +L+V P ++ +L D + G+
Sbjct: 60 LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY--------PHWVEKLNDTQLDSGS 111
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ + W +N L RV +V G + C AE
Sbjct: 112 PLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 167
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRA--LLTEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L +L P F + +L+ ++T+ V +ECK G P P + W K
Sbjct: 168 NKYGAIYASAELKILA----SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKK 223
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRA 277
R ++ A+ + + G Y C N G A
Sbjct: 224 GDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 266
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/175 (26%), Positives = 72/175 (41%), Gaps = 17/175 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E GV L + D G+Y A N G+ A L++ A PTF
Sbjct: 143 EMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA-------PTFALNQLK 194
Query: 117 LTVKVGTRTRFLVEII--SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXX 174
T+ V ++E S + ++W + +R + E +R++I+ DGS
Sbjct: 195 KTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSL---RILNASKSD 251
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVV 229
G++ C ENV G A A L+V P R E + R LT ++ L CK +
Sbjct: 252 EGKYVCRGENVFGSAEIIASLSVKEP---TRIELTPK-RTELTVGESIVLNCKAI 302
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN G+ S L V Y P +VE+L + G+ + ECK G P P
Sbjct: 71 GIYECRAENSRGKNSFRGQLQV-----YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 125
Query: 235 VLRWFKD-------SR-EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
RW K+ SR E+ G + N D G Y C A N G Y+S+++ ++
Sbjct: 126 TYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDA---GMYQCLAENKYGAIYASAELKIL 182
Query: 287 GRA 289
A
Sbjct: 183 ASA 185
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/240 (22%), Positives = 100/240 (41%), Gaps = 13/240 (5%)
Query: 54 VSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR 112
+ ++ G L + R D +Y A+N+ G +L V EE P +
Sbjct: 81 IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMG 140
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGSFFCXXXXX 169
+ K T T L + + +++W+++ + A R+ +R G+
Sbjct: 141 PQLKVVEKARTAT-MLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGAL---QIES 196
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
G++ C A N G R S A+L V V + R + ++ G+V+L C
Sbjct: 197 SEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPG-GSVNLTCVA 255
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---GTYTCEAVNCMGRAYSSSKVHV 285
VG P P ++W + E+ D + N + +++ YTC A++ +G ++++V V
Sbjct: 256 VGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTV 315
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/219 (23%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + ++ + ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YS+ + ++V V R + S+ P+S + P
Sbjct: 207 CVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP 245
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/240 (22%), Positives = 100/240 (41%), Gaps = 13/240 (5%)
Query: 54 VSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR 112
+ ++ G L + R D +Y A+N+ G +L V EE P +
Sbjct: 81 IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMG 140
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGSFFCXXXXX 169
+ K T T L + + +++W+++ + A R+ +R G+
Sbjct: 141 PQLKVVEKARTAT-MLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGAL---QIES 196
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
G++ C A N G R S A+L V V + R + ++ G+V+L C
Sbjct: 197 SEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPG-GSVNLTCVA 255
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---GTYTCEAVNCMGRAYSSSKVHV 285
VG P P ++W + E+ D + N + +++ YTC A++ +G ++++V V
Sbjct: 256 VGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTV 315
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/219 (23%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + ++ + ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YS+ + ++V V R + S+ P+S + P
Sbjct: 207 CVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP 245
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/240 (22%), Positives = 100/240 (41%), Gaps = 13/240 (5%)
Query: 54 VSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR 112
+ ++ G L + R D +Y A+N+ G +L V EE P +
Sbjct: 101 IEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMG 160
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE---RVSIVRDGSFFCXXXXX 169
+ K T T L + + +++W+++ + A R+ +R G+
Sbjct: 161 PQLKVVEKARTAT-MLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGAL---QIES 216
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKV 228
G++ C A N G R S A+L V V + R + ++ G+V+L C
Sbjct: 217 SEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPG-GSVNLTCVA 275
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---GTYTCEAVNCMGRAYSSSKVHV 285
VG P P ++W + E+ D + N + +++ YTC A++ +G ++++V V
Sbjct: 276 VGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTV 335
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/219 (23%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + ++ + ++R ++ DG+
Sbjct: 49 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGA 107
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 108 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 166
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 167 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 226
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YS+ + ++V V R + S+ P+S + P
Sbjct: 227 CVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP 265
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/223 (23%), Positives = 85/223 (38%), Gaps = 25/223 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+Y +A N+ G ++ R +L+V P ++ +L D + G+
Sbjct: 280 LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY--------PHWVEKLNDTQLDSGS 331
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ + W +N L RV +V G + C AE
Sbjct: 332 PLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 387
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRA--LLTEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L +L P F + +L+ ++T+ V +ECK G P P + W K
Sbjct: 388 NKYGAIYASAELKILA----SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKK 443
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRA 277
R ++ A+ + + G Y C N G A
Sbjct: 444 GDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 486
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/175 (26%), Positives = 72/175 (41%), Gaps = 17/175 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E GV L + D G+Y A N G+ A L++ A PTF
Sbjct: 363 EMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA-------PTFALNQLK 414
Query: 117 LTVKVGTRTRFLVEII--SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXX 174
T+ V ++E S + ++W + +R + E +R++I+ DGS
Sbjct: 415 KTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSL---RILNASKSD 471
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVV 229
G++ C ENV G A A L+V P R E + R LT ++ L CK +
Sbjct: 472 EGKYVCRGENVFGSAEIIASLSVKEP---TRIELTPK-RTELTVGESIVLNCKAI 522
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN G+ S L V Y P +VE+L + G+ + ECK G P P
Sbjct: 291 GIYECRAENSRGKNSFRGQLQV-----YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 345
Query: 235 VLRWFKD-------SR-EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
RW K+ SR E+ G + N D G Y C A N G Y+S+++ ++
Sbjct: 346 TYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDA---GMYQCLAENKYGAIYASAELKIL 402
Query: 287 GRA 289
A
Sbjct: 403 ASA 405
Score = 33.5 bits (73), Expect = 1.1
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 12/86 (13%)
Query: 206 PEFVEELRALL----TEQGTVSLECKVVGVPTPVLRWFKDSREIKAG--------DVFAL 253
P FV+E ++ +++ V+L C+V G P P RW ++ EI D +
Sbjct: 25 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 84
Query: 254 TANAEDPTSLGTYTCEAVNCMGRAYS 279
+N + G Y C A N +G S
Sbjct: 85 ISNPSEAKDSGHYQCLATNTVGSILS 110
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/223 (23%), Positives = 85/223 (38%), Gaps = 25/223 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+Y +A N+ G ++ R +L+V P ++ +L D + G+
Sbjct: 354 LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY--------PHWVEKLNDTQLDSGS 405
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R+ + W +N L RV +V G + C AE
Sbjct: 406 PLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 461
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEF-VEELRA--LLTEQGTVSLECKVVGVPTPVLRWFK 240
N G SA L +L P F + +L+ ++T+ V +ECK G P P + W K
Sbjct: 462 NKYGAIYASAELKILA----SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKK 517
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRA 277
R ++ A+ + + G Y C N G A
Sbjct: 518 GDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/175 (26%), Positives = 72/175 (41%), Gaps = 17/175 (9%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
E GV L + D G+Y A N G+ A L++ A PTF
Sbjct: 437 EMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA-------PTFALNQLK 488
Query: 117 LTVKVGTRTRFLVEII--SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXX 174
T+ V ++E S + ++W + +R + E +R++I+ DGS
Sbjct: 489 KTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSL---RILNASKSD 545
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVV 229
G++ C ENV G A A L+V P R E + R LT ++ L CK +
Sbjct: 546 EGKYVCRGENVFGSAEIIASLSVKEP---TRIELTPK-RTELTVGESIVLNCKAI 596
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN G+ S L V Y P +VE+L + G+ + ECK G P P
Sbjct: 365 GIYECRAENSRGKNSFRGQLQV-----YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 419
Query: 235 VLRWFKD-------SR-EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
RW K+ SR E+ G + N D G Y C A N G Y+S+++ ++
Sbjct: 420 TYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDA---GMYQCLAENKYGAIYASAELKIL 476
Query: 287 GRA 289
A
Sbjct: 477 ASA 479
Score = 33.5 bits (73), Expect = 1.1
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 12/86 (13%)
Query: 206 PEFVEELRALL----TEQGTVSLECKVVGVPTPVLRWFKDSREIKAG--------DVFAL 253
P FV+E ++ +++ V+L C+V G P P RW ++ EI D +
Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158
Query: 254 TANAEDPTSLGTYTCEAVNCMGRAYS 279
+N + G Y C A N +G S
Sbjct: 159 ISNPSEAKDSGHYQCLATNTVGSILS 184
>DQ248309-1|ABB55264.1| 851|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.14 protein.
Length = 851
Score = 56.4 bits (130), Expect = 1e-07
Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 15/178 (8%)
Query: 76 VYTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEI 131
V+TL + D V+L ++ + E P F + L+D TV+ G T L
Sbjct: 230 VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGA-TAVLECE 288
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+S KV W++N +L++++ IV DG +TC A++ + SC
Sbjct: 289 VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSC 346
Query: 192 SAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKAG 248
+LNV+ P EF+ L L + E+ EC++ V +WFKD EIK G
Sbjct: 347 --NLNVVPPHV----EFLRPLTDLQVREKEMARFECELSRENAKV-KWFKDGAEIKKG 397
Score = 50.4 bits (115), Expect = 9e-06
Identities = 62/242 (25%), Positives = 92/242 (38%), Gaps = 32/242 (13%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA 98
N K + A L +E G + L + R TG QA+N S RV+ V
Sbjct: 119 NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIG 178
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
LR L+D+TV G F E+ S + V WY ++L +++V
Sbjct: 179 -----------LLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKVVPRS 226
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTE 218
+G G TA++ H N+ V + EF + L E
Sbjct: 227 EGKVHTLTLRDVKLEDAGEVQLTAKDF------KTHANLFVKEP--PVEFTKPLEDQTVE 278
Query: 219 QG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE---------DPTSLGTYTC 268
+G T LEC+V V +WFK+ EI + + A+ P + TYTC
Sbjct: 279 EGATAVLECEVSRENAKV-KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 337
Query: 269 EA 270
+A
Sbjct: 338 DA 339
Score = 35.5 bits (78), Expect = 0.28
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 21/242 (8%)
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXX 173
L+D VK F E+ ++ K W+RNE + ++ + I++ +
Sbjct: 627 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 685
Query: 174 XXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLT-EQGTVSLECKVVGVP 232
+ + N G SA N++V + R VE L+ + T E+ +V+ CKV +
Sbjct: 686 DQANYNVSLTNHRGENVKSA-ANLIVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL- 741
Query: 233 TPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
L+W K+ E+ + + + + +C + ++V
Sbjct: 742 NVTLKWTKNGEEVPFDNRVSYRVDKY------KHMLTIKDC---GFPDEGEYIV----TA 788
Query: 293 GSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAG 352
G K + L E P F LEDQ V + SCQ+ +V WY +++ G
Sbjct: 789 GQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQL--SREKANVKWYRNGREIKEG 846
Query: 353 ER 354
++
Sbjct: 847 KK 848
Score = 33.5 bits (73), Expect = 1.1
Identities = 39/182 (21%), Positives = 70/182 (38%), Gaps = 21/182 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + A D G Y + ++ +V E++AE F+ + Q+L + G
Sbjct: 500 LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAE----------FISKPQNLEILEGE 548
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ F+ I S V W R+++ L ++ ++ DG G +
Sbjct: 549 KAEFVCSI-SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV- 606
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
G A +AHL V+ P +++ R + EQ V C+ V +WF++
Sbjct: 607 ---GAARAAAHLTVIEKLRIVVP--LKDTR--VKEQQEVVFNCE-VNTEGAKAKWFRNEE 658
Query: 244 EI 245
I
Sbjct: 659 AI 660
Score = 32.7 bits (71), Expect = 2.0
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI 156
E P F+ L+D TV F ++ S + V WYRN R + E +++ I
Sbjct: 801 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKIQI 851
Score = 31.5 bits (68), Expect = 4.6
Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 10/61 (16%)
Query: 218 EQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED---------PTSLGTYTC 268
E+ V L+C++ PV +WFKD +EIK + A+ + + +G YTC
Sbjct: 12 EKDEVILQCEISKADAPV-KWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC 70
Query: 269 E 269
+
Sbjct: 71 D 71
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 56.4 bits (130), Expect = 1e-07
Identities = 58/251 (23%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+++ L D S E G + LT+ + D G+Y A+N G + +
Sbjct: 62 TRNKILIKLFDTRYSIRENGQL-LTILSVEDSDDGIYCCTANNGVGGAVESCGA-LQVKM 119
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P PP ++ ++ L + T + + + V+W + + L E R++++ G
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTT------MGNPKPSVSWIKGDSPLRENSRIAVLESG 173
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRA-SCSAHLNVLV-PKAYKRPEFVEELRALLTE 218
S G++ C A+N G A S L V V + + PE +T
Sbjct: 174 SL---RIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN-----VTF 225
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDV-FALTANAEDP------TSLGTYTCEAV 271
V+L C G+P P + W ++ + +G + ++ D T G YTC A
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 272 NCMGRAYSSSK 282
N G +S++K
Sbjct: 286 NKHGEKFSTAK 296
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 56.4 bits (130), Expect = 1e-07
Identities = 58/251 (23%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+++ L D S E G + LT+ + D G+Y A+N G + +
Sbjct: 62 TRNKILIKLFDTRYSIRENGQL-LTILSVEDSDDGIYCCTANNGVGGAVESCGA-LQVKM 119
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P PP ++ ++ L + T + + + V+W + + L E R++++ G
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTT------MGNPKPSVSWIKGDSPLRENSRIAVLESG 173
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRA-SCSAHLNVLV-PKAYKRPEFVEELRALLTE 218
S G++ C A+N G A S L V V + + PE +T
Sbjct: 174 SL---RIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN-----VTF 225
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDV-FALTANAEDP------TSLGTYTCEAV 271
V+L C G+P P + W ++ + +G + ++ D T G YTC A
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 272 NCMGRAYSSSK 282
N G +S++K
Sbjct: 286 NKHGEKFSTAK 296
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 56.4 bits (130), Expect = 1e-07
Identities = 58/251 (23%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+++ L D S E G + LT+ + D G+Y A+N G + +
Sbjct: 62 TRNKILIKLFDTRYSIRENGQL-LTILSVEDSDDGIYCCTANNGVGGAVESCGA-LQVKM 119
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P PP ++ ++ L + T + + + V+W + + L E R++++ G
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTT------MGNPKPSVSWIKGDSPLRENSRIAVLESG 173
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRA-SCSAHLNVLV-PKAYKRPEFVEELRALLTE 218
S G++ C A+N G A S L V V + + PE +T
Sbjct: 174 SL---RIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN-----VTF 225
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDV-FALTANAEDP------TSLGTYTCEAV 271
V+L C G+P P + W ++ + +G + ++ D T G YTC A
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 272 NCMGRAYSSSK 282
N G +S++K
Sbjct: 286 NKHGEKFSTAK 296
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 56.4 bits (130), Expect = 1e-07
Identities = 58/251 (23%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+++ L D S E G + LT+ + D G+Y A+N G + +
Sbjct: 62 TRNKILIKLFDTRYSIRENGQL-LTILSVEDSDDGIYCCTANNGVGGAVESCGA-LQVKM 119
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P PP ++ ++ L + T + + + V+W + + L E R++++ G
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTT------MGNPKPSVSWIKGDSPLRENSRIAVLESG 173
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRA-SCSAHLNVLV-PKAYKRPEFVEELRALLTE 218
S G++ C A+N G A S L V V + + PE +T
Sbjct: 174 SL---RIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN-----VTF 225
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDV-FALTANAEDP------TSLGTYTCEAV 271
V+L C G+P P + W ++ + +G + ++ D T G YTC A
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 272 NCMGRAYSSSK 282
N G +S++K
Sbjct: 286 NKHGEKFSTAK 296
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 56.4 bits (130), Expect = 1e-07
Identities = 58/251 (23%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+++ L D S E G + LT+ + D G+Y A+N G + +
Sbjct: 62 TRNKILIKLFDTRYSIRENGQL-LTILSVEDSDDGIYCCTANNGVGGAVESCGA-LQVKM 119
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P PP ++ ++ L + T + + + V+W + + L E R++++ G
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTT------MGNPKPSVSWIKGDSPLRENSRIAVLESG 173
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRA-SCSAHLNVLV-PKAYKRPEFVEELRALLTE 218
S G++ C A+N G A S L V V + + PE +T
Sbjct: 174 SL---RIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN-----VTF 225
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDV-FALTANAEDP------TSLGTYTCEAV 271
V+L C G+P P + W ++ + +G + ++ D T G YTC A
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 272 NCMGRAYSSSK 282
N G +S++K
Sbjct: 286 NKHGEKFSTAK 296
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 56.4 bits (130), Expect = 1e-07
Identities = 58/251 (23%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+++ L D S E G + LT+ + D G+Y A+N G + +
Sbjct: 62 TRNKILIKLFDTRYSIRENGQL-LTILSVEDSDDGIYCCTANNGVGGAVESCGA-LQVKM 119
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P PP ++ ++ L + T + + + V+W + + L E R++++ G
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTT------MGNPKPSVSWIKGDSPLRENSRIAVLESG 173
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRA-SCSAHLNVLV-PKAYKRPEFVEELRALLTE 218
S G++ C A+N G A S L V V + + PE +T
Sbjct: 174 SL---RIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN-----VTF 225
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDV-FALTANAEDP------TSLGTYTCEAV 271
V+L C G+P P + W ++ + +G + ++ D T G YTC A
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 272 NCMGRAYSSSK 282
N G +S++K
Sbjct: 286 NKHGEKFSTAK 296
>EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform A
protein.
Length = 1896
Score = 56.0 bits (129), Expect = 2e-07
Identities = 65/243 (26%), Positives = 95/243 (39%), Gaps = 27/243 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEV-SAEESPSG---EDPPTFLRRL----Q 115
L + AR D+GVY A NA G A L+V ESP E P + L +
Sbjct: 194 LRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPK 253
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXX 174
V G +F ++ E ++ W+ R LL R + RD F
Sbjct: 254 TFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKD 313
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPK-AYKRPEFVEELRALLTEQGTVSLECKVVGVPT 233
G + C A N G+ + L+V P+ + RP ++++ E G LECKV
Sbjct: 314 RGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP--LQDVEG--REHGIAVLECKVPNSRI 369
Query: 234 PVLRWFKDSR---------EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVH 284
P WF++ + +I+ G V L + G Y CE GR + + V
Sbjct: 370 PT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE---MRGRVRTVANVT 425
Query: 285 VVG 287
V G
Sbjct: 426 VKG 428
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 15/137 (10%)
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED---------PTSLGTYTCEAVNCM 274
L+C V+G P PV+ W K +++ A + + A+ + PT G Y C A N
Sbjct: 31 LKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAA 90
Query: 275 GRAYSSSKVHVVGRASREGSLKPNSSGL----SPEPPPIFTRELEDQYVRICEPFTLSCQ 330
G AY+++ V V+ + + L+P L S E P+F Q+V L+C+
Sbjct: 91 GEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCR 150
Query: 331 IVVPPWPRSVVWYNKEG 347
P P +++ K+G
Sbjct: 151 AGGLPEP--TLYWEKDG 165
Score = 48.0 bits (109), Expect = 5e-05
Identities = 57/217 (26%), Positives = 79/217 (36%), Gaps = 39/217 (17%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP FLR + + V G ++ V W + ++L +ER+S DG+
Sbjct: 11 PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYK------------------RPEF 208
G + C A N G A +A + VL P A P F
Sbjct: 71 LTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVF 130
Query: 209 VEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSR---EIKAGDVFAL-TANAED---- 259
+ R+ +G V L C+ G+P P L W KD E+ FAL AED
Sbjct: 131 LTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGA 190
Query: 260 -----------PTSLGTYTCEAVNCMGRAYSSSKVHV 285
P S G Y C A N G A + + + V
Sbjct: 191 SLALRILAARLPDS-GVYVCHARNAHGHAQAGALLQV 226
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/130 (27%), Positives = 51/130 (39%), Gaps = 7/130 (5%)
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+S + V WY++ + E+E + + RDG G + C A G S
Sbjct: 1013 LSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA----GDDSA 1068
Query: 192 SAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF 251
+ V P L G V L C+V + V RW+KD E++A D
Sbjct: 1069 FFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQV-RWYKDGLEVEASD-- 1125
Query: 252 ALTANAEDPT 261
AL AE PT
Sbjct: 1126 ALQLGAEGPT 1135
Score = 41.1 bits (92), Expect = 0.006
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 17/194 (8%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
R + + GG L V + D G+Y A N+AG + V+L V E F
Sbjct: 292 RLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVK-------EPRLRFT 344
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
R LQD+ + L + ++ W+R ++RLL + + +G+
Sbjct: 345 RPLQDVEGR-EHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLK 403
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGV 231
G + C + GR A++ V P + P +L L E + +E GV
Sbjct: 404 ADDDGIYLC---EMRGRVRTVANVTVKGPILKRLP---RKLDVLEGENAVLLVETLEAGV 457
Query: 232 PTPVLRWFKDSREI 245
RW +D E+
Sbjct: 458 EG---RWSRDGEEL 468
Score = 37.9 bits (84), Expect = 0.053
Identities = 40/155 (25%), Positives = 62/155 (40%), Gaps = 16/155 (10%)
Query: 105 EDPPTFLRRLQD---LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
++ P + QD LT R E+ S + TWY++ +++ E+E + + DG
Sbjct: 711 QESPVHILSPQDRVSLTFTTSERVVLTCEL-SRVDFPATWYKDGQKVEESELLVVKMDGR 769
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV---PKAYKRPEFVEELRALLTE 218
G + C E V SA V V P P + A+ +E
Sbjct: 770 KHRLILPEAKVQDSGEFECRTEGV------SAFFGVTVQDPPVHIVDPREHVFVHAITSE 823
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
V L C+V PV RW+KD +E++ D L
Sbjct: 824 --CVMLACEVDREDAPV-RWYKDGQEVEESDFVVL 855
Score = 36.7 bits (81), Expect = 0.12
Identities = 64/229 (27%), Positives = 91/229 (39%), Gaps = 31/229 (13%)
Query: 54 VSTEEAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR 112
V E+AG + L V AR+GD G Y A +R+ L VS EE + +
Sbjct: 1315 VQLEQAGARQVLRVQGARSGDAGEYLCDAPQ-----DSRIFL-VSVEEPLLVK----LVS 1364
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
L LTV G F E+ S + VTW RN + +V + ++GS
Sbjct: 1365 ELTPLTVHEGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQL 1423
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGV 231
G T A G + SA L+V + F+ L+ + E+G V LE + V
Sbjct: 1424 GDAGTVTLRA----GSTATSARLHVRETELL----FLRRLQDVRAEEGQDVCLEVETGRV 1475
Query: 232 -PTPVLRWFK-------DSREIKA--GDVFALTANAEDPTSLGTYTCEA 270
+RW + DSR A G + L + GTY CE+
Sbjct: 1476 GAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCES 1524
>EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform C
protein.
Length = 1544
Score = 56.0 bits (129), Expect = 2e-07
Identities = 65/243 (26%), Positives = 95/243 (39%), Gaps = 27/243 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEV-SAEESPSG---EDPPTFLRRL----Q 115
L + AR D+GVY A NA G A L+V ESP E P + L +
Sbjct: 194 LRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPK 253
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXX 174
V G +F ++ E ++ W+ R LL R + RD F
Sbjct: 254 TFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKD 313
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPK-AYKRPEFVEELRALLTEQGTVSLECKVVGVPT 233
G + C A N G+ + L+V P+ + RP ++++ E G LECKV
Sbjct: 314 RGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP--LQDVEG--REHGIAVLECKVPNSRI 369
Query: 234 PVLRWFKDSR---------EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVH 284
P WF++ + +I+ G V L + G Y CE GR + + V
Sbjct: 370 PT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE---MRGRVRTVANVT 425
Query: 285 VVG 287
V G
Sbjct: 426 VKG 428
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 15/137 (10%)
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED---------PTSLGTYTCEAVNCM 274
L+C V+G P PV+ W K +++ A + + A+ + PT G Y C A N
Sbjct: 31 LKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAA 90
Query: 275 GRAYSSSKVHVVGRASREGSLKPNSSGL----SPEPPPIFTRELEDQYVRICEPFTLSCQ 330
G AY+++ V V+ + + L+P L S E P+F Q+V L+C+
Sbjct: 91 GEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCR 150
Query: 331 IVVPPWPRSVVWYNKEG 347
P P +++ K+G
Sbjct: 151 AGGLPEP--TLYWEKDG 165
Score = 48.0 bits (109), Expect = 5e-05
Identities = 57/217 (26%), Positives = 79/217 (36%), Gaps = 39/217 (17%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
PP FLR + + V G ++ V W + ++L +ER+S DG+
Sbjct: 11 PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYK------------------RPEF 208
G + C A N G A +A + VL P A P F
Sbjct: 71 LTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVF 130
Query: 209 VEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSR---EIKAGDVFAL-TANAED---- 259
+ R+ +G V L C+ G+P P L W KD E+ FAL AED
Sbjct: 131 LTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGA 190
Query: 260 -----------PTSLGTYTCEAVNCMGRAYSSSKVHV 285
P S G Y C A N G A + + + V
Sbjct: 191 SLALRILAARLPDS-GVYVCHARNAHGHAQAGALLQV 226
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/130 (27%), Positives = 51/130 (39%), Gaps = 7/130 (5%)
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+S + V WY++ + E+E + + RDG G + C A G S
Sbjct: 1014 LSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA----GDDSA 1069
Query: 192 SAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF 251
+ V P L G V L C+V + V RW+KD E++A D
Sbjct: 1070 FFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQV-RWYKDGLEVEASD-- 1126
Query: 252 ALTANAEDPT 261
AL AE PT
Sbjct: 1127 ALQLGAEGPT 1136
Score = 41.1 bits (92), Expect = 0.006
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 17/194 (8%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
R + + GG L V + D G+Y A N+AG + V+L V E F
Sbjct: 292 RLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVK-------EPRLRFT 344
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
R LQD+ + L + ++ W+R ++RLL + + +G+
Sbjct: 345 RPLQDVEGR-EHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLK 403
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGV 231
G + C + GR A++ V P + P +L L E + +E GV
Sbjct: 404 ADDDGIYLC---EMRGRVRTVANVTVKGPILKRLP---RKLDVLEGENAVLLVETLEAGV 457
Query: 232 PTPVLRWFKDSREI 245
RW +D E+
Sbjct: 458 EG---RWSRDGEEL 468
Score = 37.9 bits (84), Expect = 0.053
Identities = 40/155 (25%), Positives = 62/155 (40%), Gaps = 16/155 (10%)
Query: 105 EDPPTFLRRLQD---LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
++ P + QD LT R E+ S + TWY++ +++ E+E + + DG
Sbjct: 712 QESPVHILSPQDRVSLTFTTSERVVLTCEL-SRVDFPATWYKDGQKVEESELLVVKMDGR 770
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV---PKAYKRPEFVEELRALLTE 218
G + C E V SA V V P P + A+ +E
Sbjct: 771 KHRLILPEAKVQDSGEFECRTEGV------SAFFGVTVQDPPVHIVDPREHVFVHAITSE 824
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
V L C+V PV RW+KD +E++ D L
Sbjct: 825 --CVMLACEVDREDAPV-RWYKDGQEVEESDFVVL 856
Score = 36.7 bits (81), Expect = 0.12
Identities = 64/229 (27%), Positives = 91/229 (39%), Gaps = 31/229 (13%)
Query: 54 VSTEEAGGVR-LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR 112
V E+AG + L V AR+GD G Y A +R+ L VS EE + +
Sbjct: 1316 VQLEQAGARQVLRVQGARSGDAGEYLCDAPQ-----DSRIFL-VSVEEPLLVK----LVS 1365
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
L LTV G F E+ S + VTW RN + +V + ++GS
Sbjct: 1366 ELTPLTVHEGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQL 1424
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGV 231
G T A G + SA L+V + F+ L+ + E+G V LE + V
Sbjct: 1425 GDAGTVTLRA----GSTATSARLHVRETELL----FLRRLQDVRAEEGQDVCLEVETGRV 1476
Query: 232 -PTPVLRWFK-------DSREIKA--GDVFALTANAEDPTSLGTYTCEA 270
+RW + DSR A G + L + GTY CE+
Sbjct: 1477 GAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCES 1525
>BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein.
Length = 1044
Score = 56.0 bits (129), Expect = 2e-07
Identities = 65/243 (26%), Positives = 95/243 (39%), Gaps = 27/243 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEV-SAEESPSG---EDPPTFLRRL----Q 115
L + AR D+GVY A NA G A L+V ESP E P + L +
Sbjct: 213 LRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPK 272
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXX 174
V G +F ++ E ++ W+ R LL R + RD F
Sbjct: 273 TFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKD 332
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPK-AYKRPEFVEELRALLTEQGTVSLECKVVGVPT 233
G + C A N G+ + L+V P+ + RP ++++ E G LECKV
Sbjct: 333 RGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP--LQDVEG--REHGIAVLECKVPNSRI 388
Query: 234 PVLRWFKDSR---------EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVH 284
P WF++ + +I+ G V L + G Y CE GR + + V
Sbjct: 389 PT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE---MRGRVRTVANVT 444
Query: 285 VVG 287
V G
Sbjct: 445 VKG 447
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 15/137 (10%)
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED---------PTSLGTYTCEAVNCM 274
L+C V+G P PV+ W K +++ A + + A+ + PT G Y C A N
Sbjct: 50 LKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAA 109
Query: 275 GRAYSSSKVHVVGRASREGSLKPNSSGL----SPEPPPIFTRELEDQYVRICEPFTLSCQ 330
G AY+++ V V+ + + L+P L S E P+F Q+V L+C+
Sbjct: 110 GEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCR 169
Query: 331 IVVPPWPRSVVWYNKEG 347
P P +++ K+G
Sbjct: 170 AGGLPEP--TLYWEKDG 184
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/235 (26%), Positives = 88/235 (37%), Gaps = 41/235 (17%)
Query: 91 RVRLEVSAEESPSGED--PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL 148
R R +A ++ SG+ PP FLR + + V G ++ V W + ++L
Sbjct: 12 RCRRSAAAMKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQL 71
Query: 149 LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYK---- 204
+ER+S DG+ G + C A N G A +A + VL P A
Sbjct: 72 AASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQ 131
Query: 205 --------------RPEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSR---EIK 246
P F+ R+ +G V L C+ G+P P L W KD E+
Sbjct: 132 PAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVW 191
Query: 247 AGDVFAL-TANAED---------------PTSLGTYTCEAVNCMGRAYSSSKVHV 285
FAL AED P S G Y C A N G A + + + V
Sbjct: 192 DSSHFALQPGRAEDGPGASLALRILAARLPDS-GVYVCHARNAHGHAQAGALLQV 245
Score = 41.1 bits (92), Expect = 0.006
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 17/194 (8%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
R + + GG L V + D G+Y A N+AG + V+L V E F
Sbjct: 311 RLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVK-------EPRLRFT 363
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
R LQD+ + L + ++ W+R ++RLL + + +G+
Sbjct: 364 RPLQDVEGR-EHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLK 422
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGV 231
G + C + GR A++ V P + P +L L E + +E GV
Sbjct: 423 ADDDGIYLC---EMRGRVRTVANVTVKGPILKRLP---RKLDVLEGENAVLLVETLEAGV 476
Query: 232 PTPVLRWFKDSREI 245
RW +D E+
Sbjct: 477 EG---RWSRDGEEL 487
Score = 37.9 bits (84), Expect = 0.053
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 13/153 (8%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
E P L +++ T R ++ +S + TWY++ +++ E+E + + DG
Sbjct: 731 ESPVHILSPQDKVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKH 790
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV---PKAYKRPEFVEELRALLTEQG 220
G + C E V SA V V P P + A+ +E
Sbjct: 791 RLILPEAKVQDSGEFECRTEGV------SAFFGVTVQDPPVHIVDPREHVFVHAITSE-- 842
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
V L C+V PV RW+KD +E++ D L
Sbjct: 843 CVMLACEVDREDAPV-RWYKDGQEVEESDFVVL 874
>BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/198 (22%), Positives = 87/198 (43%), Gaps = 13/198 (6%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCX 165
PP F++ +++++ G R ++ V+WY N R + + IV +
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSL 224
G + C A+N G A+ + L+VL + + P F+ + ++ +G +V L
Sbjct: 309 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368
Query: 225 ECKVVGVPTPVLRWFKDSREIKAG-DVFALTANAEDPTSL----------GTYTCEAVNC 273
EC++ +P P L W +++ ++ D +L + +L G YT AVN
Sbjct: 369 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428
Query: 274 MGRAYSSSKVHVVGRASR 291
G ++++ V R ++
Sbjct: 429 AGVTTCNTRLDVTARPNQ 446
Score = 33.1 bits (72), Expect = 1.5
Identities = 16/42 (38%), Positives = 21/42 (50%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA 98
+ G V L + D G YT+ A N AG T RL+V+A
Sbjct: 401 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 442
>AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/198 (22%), Positives = 87/198 (43%), Gaps = 13/198 (6%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCX 165
PP F++ +++++ G R ++ V+WY N R + + IV +
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSL 224
G + C A+N G A+ + L+VL + + P F+ + ++ +G +V L
Sbjct: 309 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368
Query: 225 ECKVVGVPTPVLRWFKDSREIKAG-DVFALTANAEDPTSL----------GTYTCEAVNC 273
EC++ +P P L W +++ ++ D +L + +L G YT AVN
Sbjct: 369 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428
Query: 274 MGRAYSSSKVHVVGRASR 291
G ++++ V R ++
Sbjct: 429 AGVTTCNTRLDVTARPNQ 446
Score = 33.1 bits (72), Expect = 1.5
Identities = 16/42 (38%), Positives = 21/42 (50%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA 98
+ G V L + D G YT+ A N AG T RL+V+A
Sbjct: 401 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 442
>AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein
protein.
Length = 498
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/198 (22%), Positives = 87/198 (43%), Gaps = 13/198 (6%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCX 165
PP F++ +++++ G R ++ V+WY N R + + IV +
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSL 224
G + C A+N G A+ + L+VL + + P F+ + ++ +G +V L
Sbjct: 309 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368
Query: 225 ECKVVGVPTPVLRWFKDSREIKAG-DVFALTANAEDPTSL----------GTYTCEAVNC 273
EC++ +P P L W +++ ++ D +L + +L G YT AVN
Sbjct: 369 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428
Query: 274 MGRAYSSSKVHVVGRASR 291
G ++++ V R ++
Sbjct: 429 AGVTTCNTRLDVTARPNQ 446
Score = 33.1 bits (72), Expect = 1.5
Identities = 16/42 (38%), Positives = 21/42 (50%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA 98
+ G V L + D G YT+ A N AG T RL+V+A
Sbjct: 401 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 442
>AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein.
Length = 1237
Score = 56.0 bits (129), Expect = 2e-07
Identities = 65/243 (26%), Positives = 95/243 (39%), Gaps = 27/243 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEV-SAEESPSG---EDPPTFLRRL----Q 115
L + AR D+GVY A NA G A L+V ESP E P + L +
Sbjct: 30 LRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPK 89
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXXXXXXXXXX 174
V G +F ++ E ++ W+ R LL R + RD F
Sbjct: 90 TFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKD 149
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPK-AYKRPEFVEELRALLTEQGTVSLECKVVGVPT 233
G + C A N G+ + L+V P+ + RP ++++ E G LECKV
Sbjct: 150 RGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP--LQDVEG--REHGIAVLECKVPNSRI 205
Query: 234 PVLRWFKDSR---------EIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVH 284
P WF++ + +I+ G V L + G Y CE GR + + V
Sbjct: 206 PT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE---MRGRVRTVANVT 261
Query: 285 VVG 287
V G
Sbjct: 262 VKG 264
Score = 41.1 bits (92), Expect = 0.006
Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 17/194 (8%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
R + + GG L V + D G+Y A N+AG + V+L V E F
Sbjct: 128 RLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVK-------EPRLRFT 180
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
R LQD+ + L + ++ W+R ++RLL + + +G+
Sbjct: 181 RPLQDVEGR-EHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLK 239
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGV 231
G + C + GR A++ V P + P +L L E + +E GV
Sbjct: 240 ADDDGIYLC---EMRGRVRTVANVTVKGPILKRLP---RKLDVLEGENAVLLVETLEAGV 293
Query: 232 PTPVLRWFKDSREI 245
RW +D E+
Sbjct: 294 EG---RWSRDGEEL 304
Score = 37.9 bits (84), Expect = 0.053
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 13/153 (8%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEI-ISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
E P L +++ T R ++ +S + TWY++ +++ E+E + + DG
Sbjct: 548 ESPVHILSPQDKVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKH 607
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLV---PKAYKRPEFVEELRALLTEQG 220
G + C E V SA V V P P + A+ +E
Sbjct: 608 RLILPEAKVQDSGEFECRTEGV------SAFFGVTVQDPPVHIVDPREHVFVHAITSE-- 659
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
V L C+V PV RW+KD +E++ D L
Sbjct: 660 CVMLACEVDREDAPV-RWYKDGQEVEESDFVVL 691
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/251 (27%), Positives = 90/251 (35%), Gaps = 24/251 (9%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D V+ +GG L + GD+G Y A+N S A + V A P F
Sbjct: 403 DPRVNITPSGG--LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL--------PQF 452
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
QD V G F E + + W + +L R ++ G+
Sbjct: 453 TVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTL---RISGV 509
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVV 229
G++ C A N+ G AHL V P+ P F E G V L C
Sbjct: 510 ALHDQGQYECQAVNIIGSQKVVAHLTVQ-PRV--TPVFASIPSDTTVEVGANVQLPCSSQ 566
Query: 230 GVPTPVLRWFKDSREIKAGDVF------ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
G P P + W KD ++ F LT N P G Y C A N +G A S +
Sbjct: 567 GEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 626
Query: 284 HV-VGRASREG 293
V V SR G
Sbjct: 627 SVNVPDVSRNG 637
Score = 52.8 bits (121), Expect = 2e-06
Identities = 69/287 (24%), Positives = 109/287 (37%), Gaps = 29/287 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
L + + D G+Y A N AG T V L SP+ PTF+ + Q+ V VG
Sbjct: 319 LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFG--SPAR---PTFVIQPQNTEVLVG 373
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
+++W R +R L + RV+I G + G + C+
Sbjct: 374 ESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDS---GEYACS 430
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N +A + V P+F V ++ E TV +C+ G P PV+ W K
Sbjct: 431 ATNNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK 485
Query: 241 DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
++ D L ++ G A++ G+ Y V+++G L
Sbjct: 486 GGSQLSV-DRRHLVLSSGTLRISGV----ALHDQGQ-YECQAVNIIGSQKVVAHLT---- 535
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
+ P P+F D V + L C P P ++ W NK+G
Sbjct: 536 -VQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEP-AITW-NKDG 579
Score = 45.2 bits (102), Expect = 4e-04
Identities = 43/160 (26%), Positives = 61/160 (38%), Gaps = 12/160 (7%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
TK + S+D R + L +S D G Y QA N GS L V
Sbjct: 484 TKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRV 540
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
+P P+ D TV+VG + E +TW ++ ++ E+ + I +G
Sbjct: 541 TPVFASIPS------DTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG 594
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
GR+ C A N G AS S L+V VP
Sbjct: 595 FL---TINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/251 (27%), Positives = 90/251 (35%), Gaps = 24/251 (9%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D V+ +GG L + GD+G Y A+N S A + V A P F
Sbjct: 381 DPRVNITPSGG--LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL--------PQF 430
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
QD V G F E + + W + +L R ++ G+
Sbjct: 431 TVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTL---RISGV 487
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVV 229
G++ C A N+ G AHL V P+ P F E G V L C
Sbjct: 488 ALHDQGQYECQAVNIIGSQKVVAHLTVQ-PRV--TPVFASIPSDTTVEVGANVQLPCSSQ 544
Query: 230 GVPTPVLRWFKDSREIKAGDVF------ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
G P P + W KD ++ F LT N P G Y C A N +G A S +
Sbjct: 545 GEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 604
Query: 284 HV-VGRASREG 293
V V SR G
Sbjct: 605 SVNVPDVSRNG 615
Score = 52.8 bits (121), Expect = 2e-06
Identities = 69/287 (24%), Positives = 109/287 (37%), Gaps = 29/287 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
L + + D G+Y A N AG T V L SP+ PTF+ + Q+ V VG
Sbjct: 297 LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFG--SPAR---PTFVIQPQNTEVLVG 351
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
+++W R +R L + RV+I G + G + C+
Sbjct: 352 ESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDS---GEYACS 408
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N +A + V P+F V ++ E TV +C+ G P PV+ W K
Sbjct: 409 ATNNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK 463
Query: 241 DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
++ D L ++ G A++ G+ Y V+++G L
Sbjct: 464 GGSQLSV-DRRHLVLSSGTLRISGV----ALHDQGQ-YECQAVNIIGSQKVVAHLT---- 513
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
+ P P+F D V + L C P P ++ W NK+G
Sbjct: 514 -VQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEP-AITW-NKDG 557
Score = 45.2 bits (102), Expect = 4e-04
Identities = 43/160 (26%), Positives = 61/160 (38%), Gaps = 12/160 (7%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
TK + S+D R + L +S D G Y QA N GS L V
Sbjct: 462 TKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRV 518
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
+P P+ D TV+VG + E +TW ++ ++ E+ + I +G
Sbjct: 519 TPVFASIPS------DTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG 572
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
GR+ C A N G AS S L+V VP
Sbjct: 573 FL---TINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 609
>BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein.
Length = 347
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 24/226 (10%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + +++ ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV-SSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHVVGRASREG-SLKPNS----SGLSPEPP 307
C A N G YS+ + ++V G+ S L P S +GLS + P
Sbjct: 207 CVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSP 252
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 25/231 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+Y A N+ G + AR +L A+ P +++++ D+ V +
Sbjct: 280 LEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQ--------PNWIQKINDIHVAMEE 331
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + + W +N LL +R+ I G+ G + C AE
Sbjct: 332 NVFWECKANGRPKPTYKWLKNGEPLLTRDRIQI-EQGTL---NITIVNLSDAGMYQCLAE 387
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELR---ALLTEQGTVSLECKVVGVPTPVLRWFK 240
N G +A L+V+ P+F L L+ G V +ECK P PV W K
Sbjct: 388 NKHGVIFSNAELSVIAVG----PDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKK 443
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+K + ++ + + G+YTC A N G A S+ + V
Sbjct: 444 GRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV 494
Score = 40.7 bits (91), Expect = 0.008
Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 11/117 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTP 234
G + C AEN G+ L Y +P +++++ + + + V ECK G P P
Sbjct: 291 GLYECVAENSRGKNVARGQLTF-----YAQPNWIQKINDIHVAMEENVFWECKANGRPKP 345
Query: 235 VLRWFKDSREIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+W K+ + D L + + G Y C A N G +S++++ V+
Sbjct: 346 TYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI 402
Score = 35.9 bits (79), Expect = 0.22
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 12/86 (13%)
Query: 206 PEFVEELRALL----TEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF--------AL 253
P F++E ++ +E+ V L C+V G P P +RW + ++ G F L
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLL 85
Query: 254 TANAEDPTSLGTYTCEAVNCMGRAYS 279
N GTY C A N G S
Sbjct: 86 INNPNKTQDAGTYQCTATNSFGTIVS 111
>AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 347
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 24/226 (10%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + +++ ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV-SSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHVVGRASREG-SLKPNS----SGLSPEPP 307
C A N G YS+ + ++V G+ S L P S +GLS + P
Sbjct: 207 CVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSP 252
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 55.6 bits (128), Expect = 2e-07
Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 24/227 (10%)
Query: 57 EEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQD 116
+E+G + A + G Y A + AG+ A+ ++ V+ DPP L +
Sbjct: 437 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVT--------DPPPQLVPAPN 488
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXXXXXXXXXX 175
+TV G ++ +TW R+ R L RV+ + D S
Sbjct: 489 VTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSL---EISGIIPTDG 545
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
GR+ C A N G S L LV +A P+ + QG V + C G PTP
Sbjct: 546 GRYQCVASNANGVTRASVWL--LVREA---PQVSIHTSSQHFSQGVEVKVSCSASGYPTP 600
Query: 235 VLRWFKDSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMG 275
+ W ++S+ ++ + A P G Y+C+A N +G
Sbjct: 601 HISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG 647
Score = 43.2 bits (97), Expect = 0.001
Identities = 56/226 (24%), Positives = 81/226 (35%), Gaps = 19/226 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S D G Y ASNA G A V L V E+P + Q + VKV
Sbjct: 535 LEISGIIPTDGGRYQCVASNANGVTRASVWLLV--REAPQVSIHTSSQHFSQGVEVKVSC 592
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
++W R + L E R+ + G+ G ++C A
Sbjct: 593 SAS------GYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDA---GNYSCQAT 643
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR 243
N G + L P + V L+ L C+ GVP P + W++
Sbjct: 644 NEVGTDQETVTLYYTDPPSVSAVNAV----VLVAVGEEAVLVCEASGVPPPRVIWYRGGL 699
Query: 244 EI----KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
E+ + L A GTYTC AVN +G A + ++ V
Sbjct: 700 EMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745
>AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 55.6 bits (128), Expect = 2e-07
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 13/122 (10%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTP 234
G ++CTA+N G S +A L VL + P V L + G TV+L+CK G P P
Sbjct: 58 GVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLEDRVVSVGETVALQCKATGNPPP 112
Query: 235 VLRWFKDSREIKAGDVFALTANAE-------DPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
+ WFK R + + LT + + G YTCE N +G + S++ V+
Sbjct: 113 RITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 172
Query: 288 RA 289
A
Sbjct: 173 AA 174
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D GVY+ A N+AGS +A L V E+PS P L+D V VG
Sbjct: 49 ITDVKIDDAGVYSCTAQNSAGSISANATLTVL--ETPSLVVP------LEDRVVSVGETV 100
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
+ + ++TW++ +R L ER + D GR+TC N
Sbjct: 101 ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLL--VVQNVVAEDAGRYTCEMSNT 158
Query: 186 GGRASCSAHLNVL 198
G + L+VL
Sbjct: 159 LGTERAHSQLSVL 171
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 55.6 bits (128), Expect = 2e-07
Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 25/231 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G+Y A N+ G + AR +L A+ P +++++ D+ V +
Sbjct: 280 LEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQ--------PNWIQKINDIHVAMEE 331
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + + W +N LL +R+ I G+ G + C AE
Sbjct: 332 NVFWECKANGRPKPTYKWLKNGEPLLTRDRIQI-EQGTL---NITIVNLSDAGMYQCLAE 387
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELR---ALLTEQGTVSLECKVVGVPTPVLRWFK 240
N G +A L+V+ P+F L L+ G V +ECK P PV W K
Sbjct: 388 NKHGVIFSNAELSVIAVG----PDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKK 443
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+K + ++ + + G+YTC A N G A S+ + V
Sbjct: 444 GRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV 494
Score = 40.7 bits (91), Expect = 0.008
Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 11/117 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTP 234
G + C AEN G+ L Y +P +++++ + + + V ECK G P P
Sbjct: 291 GLYECVAENSRGKNVARGQLTF-----YAQPNWIQKINDIHVAMEENVFWECKANGRPKP 345
Query: 235 VLRWFKDSREIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+W K+ + D L + + G Y C A N G +S++++ V+
Sbjct: 346 TYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI 402
Score = 35.9 bits (79), Expect = 0.22
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 12/86 (13%)
Query: 206 PEFVEELRALL----TEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF--------AL 253
P F++E ++ +E+ V L C+V G P P +RW + ++ G F L
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLL 85
Query: 254 TANAEDPTSLGTYTCEAVNCMGRAYS 279
N GTY C A N G S
Sbjct: 86 INNPNKTQDAGTYQCTATNSFGTIVS 111
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/251 (27%), Positives = 90/251 (35%), Gaps = 24/251 (9%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D V+ +GG L + GD+G Y A+N S A + V A P F
Sbjct: 403 DPRVNITPSGG--LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL--------PQF 452
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
QD V G F E + + W + +L R ++ G+
Sbjct: 453 TVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTL---RISGV 509
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVV 229
G++ C A N+ G AHL V P+ P F E G V L C
Sbjct: 510 ALHDQGQYECQAVNIIGSQKVVAHLTVQ-PRV--TPVFASIPSDTTVEVGANVQLPCSSQ 566
Query: 230 GVPTPVLRWFKDSREIKAGDVF------ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
G P P + W KD ++ F LT N P G Y C A N +G A S +
Sbjct: 567 GEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 626
Query: 284 HV-VGRASREG 293
V V SR G
Sbjct: 627 SVNVPDVSRNG 637
Score = 52.8 bits (121), Expect = 2e-06
Identities = 69/287 (24%), Positives = 109/287 (37%), Gaps = 29/287 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
L + + D G+Y A N AG T V L SP+ PTF+ + Q+ V VG
Sbjct: 319 LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFG--SPAR---PTFVIQPQNTEVLVG 373
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCT 181
+++W R +R L + RV+I G + G + C+
Sbjct: 374 ESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDS---GEYACS 430
Query: 182 AENVGGRASCSAHLNVLVPKAYKRPEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
A N +A + V P+F V ++ E TV +C+ G P PV+ W K
Sbjct: 431 ATNNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK 485
Query: 241 DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSS 300
++ D L ++ G A++ G+ Y V+++G L
Sbjct: 486 GGSQLSV-DRRHLVLSSGTLRISGV----ALHDQGQ-YECQAVNIIGSQKVVAHLT---- 535
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
+ P P+F D V + L C P P ++ W NK+G
Sbjct: 536 -VQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEP-AITW-NKDG 579
Score = 45.2 bits (102), Expect = 4e-04
Identities = 43/160 (26%), Positives = 61/160 (38%), Gaps = 12/160 (7%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
TK + S+D R + L +S D G Y QA N GS L V
Sbjct: 484 TKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRV 540
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
+P P+ D TV+VG + E +TW ++ ++ E+ + I +G
Sbjct: 541 TPVFASIPS------DTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG 594
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
GR+ C A N G AS S L+V VP
Sbjct: 595 FL---TINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 55.2 bits (127), Expect = 3e-07
Identities = 57/262 (21%), Positives = 98/262 (37%), Gaps = 21/262 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
F+ ++R LDDR + L +S A GD G+Y + G +E+
Sbjct: 182 FVRWEQNRQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCVVESG-GPPKYSDEVEL 237
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL--LEAERV 154
P FL++ L +G + W +NE L +ER+
Sbjct: 238 KVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERL 297
Query: 155 SIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
++ GS G + C A+N A L V +PEF+++
Sbjct: 298 VLLAGGSL---EISDVTEDDAGTYFCIADNGNETIEAQAELTVQA-----QPEFLKQPTN 349
Query: 215 LLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE------DPTSLGTYT 267
+ + + EC+V G PTP ++W K+ + D F + + G Y
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQ 409
Query: 268 CEAVNCMGRAYSSSKVHVVGRA 289
C A N +G A + +++ ++ A
Sbjct: 410 CIAENDVGNAQAGAQLIILEHA 431
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 55.2 bits (127), Expect = 3e-07
Identities = 57/262 (21%), Positives = 98/262 (37%), Gaps = 21/262 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
F+ ++R LDDR + L +S A GD G+Y + G +E+
Sbjct: 182 FVRWEQNRQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCVVESG-GPPKYSDEVEL 237
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL--LEAERV 154
P FL++ L +G + W +NE L +ER+
Sbjct: 238 KVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERL 297
Query: 155 SIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
++ GS G + C A+N A L V +PEF+++
Sbjct: 298 VLLAGGSL---EISDVTEDDAGTYFCIADNGNETIEAQAELTVQA-----QPEFLKQPTN 349
Query: 215 LLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE------DPTSLGTYT 267
+ + + EC+V G PTP ++W K+ + D F + + G Y
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQ 409
Query: 268 CEAVNCMGRAYSSSKVHVVGRA 289
C A N +G A + +++ ++ A
Sbjct: 410 CIAENDVGNAQAGAQLIILEHA 431
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 55.2 bits (127), Expect = 3e-07
Identities = 57/262 (21%), Positives = 98/262 (37%), Gaps = 21/262 (8%)
Query: 37 FILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
F+ ++R LDDR + L +S A GD G+Y + G +E+
Sbjct: 182 FVRWEQNRQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCVVESG-GPPKYSDEVEL 237
Query: 97 SAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL--LEAERV 154
P FL++ L +G + W +NE L +ER+
Sbjct: 238 KVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERL 297
Query: 155 SIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA 214
++ GS G + C A+N A L V +PEF+++
Sbjct: 298 VLLAGGSL---EISDVTEDDAGTYFCIADNGNETIEAQAELTVQA-----QPEFLKQPTN 349
Query: 215 LLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAE------DPTSLGTYT 267
+ + + EC+V G PTP ++W K+ + D F + + G Y
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQ 409
Query: 268 CEAVNCMGRAYSSSKVHVVGRA 289
C A N +G A + +++ ++ A
Sbjct: 410 CIAENDVGNAQAGAQLIILEHA 431
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 54.8 bits (126), Expect = 4e-07
Identities = 59/258 (22%), Positives = 104/258 (40%), Gaps = 29/258 (11%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+++ L D S E G + LT+ + D G+Y A+N G + +
Sbjct: 62 TRNKILIKLFDTRYSIRENGQL-LTILSVEDSDDGIYCCTANNGVGGAVESCGA-LQVKM 119
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P PP ++ ++ L + T + + + V+W + + L E R++++ G
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTT------MGNPKPSVSWIKGDSPLRENSRIAVLESG 173
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPE-----FVEELRAL 215
S G++ C A+N G A + + L + PE F LRA
Sbjct: 174 SL---RIHNVQKEDAGQYRCVAKNSLGTAY--SKVVKLEVEEESEPEQDTKVFARILRAP 228
Query: 216 LTEQGT----VSLECKVVGVPTPVLRWFKDSREIKAGDV-FALTANAEDP------TSLG 264
+ T V+L C G+P P + W ++ + +G + ++ D T G
Sbjct: 229 ESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPG 288
Query: 265 TYTCEAVNCMGRAYSSSK 282
YTC A N G +S++K
Sbjct: 289 LYTCIATNKHGEKFSTAK 306
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 54.4 bits (125), Expect = 6e-07
Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 18/219 (8%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL--LEAERVSIVRDG 160
+ E+PP F++ +D G F+ + + +VTW + +++ E +
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ C A+N G + A L VL +P + + +L+ ++
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
T ++ C G P P + WFKD + IK AL + + T G Y
Sbjct: 147 ERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YSS + ++V V R + S+ P S + P
Sbjct: 207 CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMP 245
Score = 54.0 bits (124), Expect = 8e-07
Identities = 61/247 (24%), Positives = 103/247 (41%), Gaps = 18/247 (7%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSA 98
N K + S + +E+ G L + RT D VY A N+ G T +L V
Sbjct: 67 NKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR 126
Query: 99 EES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE---R 153
E+ PSG P Q L V TRT ++ S + ++TW+++ + + R
Sbjct: 127 EDQLPSGF--PNIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 183
Query: 154 VSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEEL 212
+ +R G+ G++ C A N G R S A+L V V + R +
Sbjct: 184 IKQLRSGAL---QIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMS 240
Query: 213 RALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT----SLGTYTC 268
++ G V++ C VG P P ++W + + ++ D + N + T S + C
Sbjct: 241 HEIMPG-GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYHPC 299
Query: 269 EAVNCMG 275
A++ +G
Sbjct: 300 VAMSSLG 306
Score = 30.7 bits (66), Expect = 8.1
Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
G + E PP F +E +DQ + CQ P PR V W NK+GK +R
Sbjct: 26 GCAAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPR-VTW-NKKGKKVNSQR 77
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 54.4 bits (125), Expect = 6e-07
Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 18/219 (8%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL--LEAERVSIVRDG 160
+ E+PP F++ +D G F+ + + +VTW + +++ E +
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ C A+N G + A L VL +P + + +L+ ++
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
T ++ C G P P + WFKD + IK AL + + T G Y
Sbjct: 147 ERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPNSSGLSP 304
C A N G YSS + ++V V R + S+ P S + P
Sbjct: 207 CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMP 245
Score = 54.0 bits (124), Expect = 8e-07
Identities = 61/247 (24%), Positives = 103/247 (41%), Gaps = 18/247 (7%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSA 98
N K + S + +E+ G L + RT D VY A N+ G T +L V
Sbjct: 67 NKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR 126
Query: 99 EES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE---R 153
E+ PSG P Q L V TRT ++ S + ++TW+++ + + R
Sbjct: 127 EDQLPSGF--PNIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 183
Query: 154 VSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVEEL 212
+ +R G+ G++ C A N G R S A+L V V + R +
Sbjct: 184 IKQLRSGAL---QIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMS 240
Query: 213 RALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT----SLGTYTC 268
++ G V++ C VG P P ++W + + ++ D + N + T S + C
Sbjct: 241 HEIMPG-GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYHPC 299
Query: 269 EAVNCMG 275
A++ +G
Sbjct: 300 VAMSSLG 306
Score = 30.7 bits (66), Expect = 8.1
Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 301 GLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
G + E PP F +E +DQ + CQ P PR V W NK+GK +R
Sbjct: 26 GCAAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPR-VTW-NKKGKKVNSQR 77
>BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein
protein.
Length = 1263
Score = 54.4 bits (125), Expect = 6e-07
Identities = 80/341 (23%), Positives = 129/341 (37%), Gaps = 45/341 (13%)
Query: 51 DRFVSTEEAGGV-RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP- 108
D + E G V L +S + G+ G Y A N G + +++ +E PP
Sbjct: 885 DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 944
Query: 109 -TFLRRLQ-DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER-VSIVRDGSFFCX 165
T ++ DL +RT EI+ E +E+ + E E+ V IV F
Sbjct: 945 VTHQHVMEFDLEHTTSSRTPSPQEIVLEVEL------SEKDVKEFEKQVKIVTVPEFTPD 998
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSL 224
+ N+ R L + + P F+ + + E
Sbjct: 999 HKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVF 1058
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAVNCM 274
+C V+G+PTP ++W+K+ I+ ++ + + + +L TY C AVNC+
Sbjct: 1059 KCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCV 1118
Query: 275 GRAY--------SSSKVHVVGRASR--------EGSLKPNSSG-----LSPEPPPIFTRE 313
G A S V+ + S+ E LK N + E PP F +
Sbjct: 1119 GEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKG 1178
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ D Y I C + P P +V WY K+GK+ G R
Sbjct: 1179 ISDCYAPIGTAAYFQCLVRGSPRP-TVYWY-KDGKLVQGRR 1217
Score = 48.0 bits (109), Expect = 5e-05
Identities = 29/101 (28%), Positives = 44/101 (43%)
Query: 98 AEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
A E E PP+F+ L V T F+VE+ V WYRN+ L ER+ +
Sbjct: 832 AIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKME 891
Query: 158 RDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
R G+ G + C A N+ G A A+++++
Sbjct: 892 RVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 932
Score = 41.1 bits (92), Expect = 0.006
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 10/102 (9%)
Query: 206 PEFVEEL-RALLTEQGTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P F+E L + + E T+ +V G+P P ++W+++ + + G+V +L
Sbjct: 842 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEI 901
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKP 297
+ G Y C AVN +G A S + V ++ + R +L P
Sbjct: 902 SNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPP 943
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS-FF 163
E PP F++ + D +GT F + S V WY+ + +L++ R ++ G+ F
Sbjct: 1170 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYK-DGKLVQGRRFTVEESGTGFH 1228
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G + C A N G A A L +
Sbjct: 1229 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 1262
>AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens
cDNA FLJ34965 fis, clone NTONG2004308. ).
Length = 885
Score = 54.4 bits (125), Expect = 6e-07
Identities = 80/341 (23%), Positives = 129/341 (37%), Gaps = 45/341 (13%)
Query: 51 DRFVSTEEAGGV-RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP- 108
D + E G V L +S + G+ G Y A N G + +++ +E PP
Sbjct: 507 DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 566
Query: 109 -TFLRRLQ-DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAER-VSIVRDGSFFCX 165
T ++ DL +RT EI+ E +E+ + E E+ V IV F
Sbjct: 567 VTHQHVMEFDLEHTTSSRTPSPQEIVLEVEL------SEKDVKEFEKQVKIVTVPDFTPD 620
Query: 166 XXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSL 224
+ N+ R L + + P F+ + + E
Sbjct: 621 HKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVF 680
Query: 225 ECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL----------GTYTCEAVNCM 274
+C V+G+PTP ++W+K+ I+ ++ + + + +L TY C AVNC+
Sbjct: 681 KCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCV 740
Query: 275 GRAY--------SSSKVHVVGRASR--------EGSLKPNSSG-----LSPEPPPIFTRE 313
G A S V+ + S+ E LK N + E PP F +
Sbjct: 741 GEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKG 800
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGER 354
+ D Y I C + P P +V WY K+GK+ G R
Sbjct: 801 ISDCYAPIGTAAYFQCLVRGSPRP-TVYWY-KDGKLVQGRR 839
Score = 48.0 bits (109), Expect = 5e-05
Identities = 29/101 (28%), Positives = 44/101 (43%)
Query: 98 AEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
A E E PP+F+ L V T F+VE+ V WYRN+ L ER+ +
Sbjct: 454 AIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKME 513
Query: 158 RDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
R G+ G + C A N+ G A A+++++
Sbjct: 514 RVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 554
Score = 41.1 bits (92), Expect = 0.006
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 10/102 (9%)
Query: 206 PEFVEEL-RALLTEQGTVSLECKVVGVPTPVLRWFKDSREI---------KAGDVFALTA 255
P F+E L + + E T+ +V G+P P ++W+++ + + G+V +L
Sbjct: 464 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEI 523
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKP 297
+ G Y C AVN +G A S + V ++ + R +L P
Sbjct: 524 SNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPP 565
Score = 40.7 bits (91), Expect = 0.008
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS-FF 163
E PP F++ + D +GT F + S V WY+ + +L++ R ++ G+ F
Sbjct: 792 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYK-DGKLVQGRRFTVEESGTGFH 850
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G + C A N G A A L +
Sbjct: 851 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 884
>BC043916-1|AAH43916.1| 767|Homo sapiens OBSCN protein protein.
Length = 767
Score = 54.0 bits (124), Expect = 8e-07
Identities = 57/229 (24%), Positives = 93/229 (40%), Gaps = 28/229 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 549 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 607
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 608 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 665
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 666 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 718
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
G LT +A + TYTC+ +G+A S +++ V G A++
Sbjct: 719 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGEAAK 763
>AL353593-2|CAI19284.1| 416|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 416
Score = 54.0 bits (124), Expect = 8e-07
Identities = 57/229 (24%), Positives = 93/229 (40%), Gaps = 28/229 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 198 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 256
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 257 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 314
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 315 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 367
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
G LT +A + TYTC+ +G+A S +++ V G A++
Sbjct: 368 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGEAAK 412
>AL353593-1|CAI19283.1| 709|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 709
Score = 54.0 bits (124), Expect = 8e-07
Identities = 57/229 (24%), Positives = 93/229 (40%), Gaps = 28/229 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 491 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 549
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 550 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 607
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 608 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 660
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
G LT +A + TYTC+ +G+A S +++ V G A++
Sbjct: 661 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGEAAK 705
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 54.0 bits (124), Expect = 8e-07
Identities = 58/234 (24%), Positives = 89/234 (38%), Gaps = 23/234 (9%)
Query: 54 VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRR 113
++ E + +L + A+ D G YT +A N G +A ++L V +P + P
Sbjct: 3 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVG--HAPQLTELP----- 55
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR----LLEAERVSIVRDGSFFCXXXXX 169
+D+TV++G VTW R + + L A R S R
Sbjct: 56 -RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFES 114
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKV 228
+ C A NV G+ A L+ + P+ + +G VSL C V
Sbjct: 115 VAPEDQAPYVCEARNVFGKVQAEAR---LIVTGHAPPQIASSAPTVRVLEGQPVSLPCIV 171
Query: 229 V-GVPTPVLRWFKDSREIKAGDVFALTANAE---D---PTSLGTYTCEAVNCMG 275
+ G P P W KD R + G ++ A+ D G Y+C A N G
Sbjct: 172 LAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG 225
Score = 51.2 bits (117), Expect = 5e-06
Identities = 65/253 (25%), Positives = 92/253 (36%), Gaps = 32/253 (12%)
Query: 44 RAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPS 103
R GA R S + GV S A D Y +A N G A RL V+ P
Sbjct: 93 RLGAGRGSR--SRQPDSGVLFFESVAPE-DQAPYVCEARNVFGKVQAEARLIVTGHAPPQ 149
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFF 163
+R L+ V + + + + W ++ R L R SI DGS
Sbjct: 150 IASSAPTVRVLEGQPVSLPC-----IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLH 204
Query: 164 CXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-V 222
GR++C A N G L V VP P +T +G
Sbjct: 205 LDRALQEHA---GRYSCVATNTAGSQHRDVELVVQVP-----PRIHPTATHHITNEGVPA 256
Query: 223 SLECKVVGVPTPVLRWFKDSREI----------KAGDVFALTANAEDPTSLGTYTCEAVN 272
SL C GVP P + W K++ + K G + +A+D G Y C A N
Sbjct: 257 SLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQD---AGAYVCTATN 313
Query: 273 CMGRAYSSSKVHV 285
+G +SS ++ +
Sbjct: 314 TVG--FSSQEMRL 324
Score = 38.3 bits (85), Expect = 0.040
Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 10/125 (8%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQG--TVSLECKVVGVP 232
G + CTA N G +S L+V P+ + ++ +T + V+L+C+ G P
Sbjct: 305 GAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSP 364
Query: 233 TPVLRWFKDSREI-KAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHV 285
P++ W KDSR + + + L + G Y C A N G A + V
Sbjct: 365 PPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGV 424
Query: 286 VGRAS 290
GR S
Sbjct: 425 QGRTS 429
Score = 34.7 bits (76), Expect = 0.50
Identities = 32/128 (25%), Positives = 46/128 (35%), Gaps = 5/128 (3%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ D G Y A+N G + +RL V+ + LQ +T K G
Sbjct: 294 LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQ-VTAKAGE 352
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLE-AERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E S VTW ++ R + R ++ GS G + CTA
Sbjct: 353 EVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSL---RLAQVQVGDSGHYECTA 409
Query: 183 ENVGGRAS 190
N G AS
Sbjct: 410 SNPAGSAS 417
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 313 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 370
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 371 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 430
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 431 SLGEATCTAELIV 443
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 348 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 407
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 408 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 451
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 846 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 903
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 904 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 963
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 964 SLGEATCTAELIV 976
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 881 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 940
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 941 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 984
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 167 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 226
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 227 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 265
Score = 42.3 bits (95), Expect = 0.002
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 176 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 235
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPE--PPPIFTRE 313
P G Y C A N G+A S +V V + E + P P+ PPP+ E
Sbjct: 236 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSPPPVLGTE 295
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 296 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 331
Score = 33.1 bits (72), Expect = 1.5
Identities = 19/109 (17%), Positives = 42/109 (38%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 298 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 357
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
E+E + + + G +T EN G +L+V+
Sbjct: 358 ESEHMKVENSENGSKLTILAGRQEHCGCYTLLVENKSGSRQAQVNLSVV 406
Score = 33.1 bits (72), Expect = 1.5
Identities = 20/59 (33%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ R G YTL N +GS A+V L V + P P R LT+
Sbjct: 370 GSKLTILAGRQEHCGCYTLLVENKSGSRQAQVNLSVVDKPDPPAGTPCASDIRSSSLTL 428
>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
sigma protein.
Length = 1948
Score = 53.2 bits (122), Expect = 1e-06
Identities = 63/255 (24%), Positives = 106/255 (41%), Gaps = 22/255 (8%)
Query: 40 NTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEVSA 98
N K + S + +E+ G L + RT D VY A N+ G T +L V
Sbjct: 67 NKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR 126
Query: 99 EES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE---R 153
E+ PSG P Q L V TRT ++ S + ++TW+++ + + R
Sbjct: 127 EDQLPSGF--PNIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 183
Query: 154 VSIVRDGSFFCX------XXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKR- 205
+ +R +F G++ C A N G R S A+L V + +R
Sbjct: 184 IKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRV 243
Query: 206 -PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL 263
P F + + + G V++ C VG P P ++W + + ++ D + N + T +
Sbjct: 244 APRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDV 303
Query: 264 ---GTYTCEAVNCMG 275
YTC A++ +G
Sbjct: 304 KDSANYTCVAMSSLG 318
Score = 44.4 bits (100), Expect = 6e-04
Identities = 47/202 (23%), Positives = 78/202 (38%), Gaps = 25/202 (12%)
Query: 103 SGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSF 162
+ E+PP F++ +D G F+ + + +VTW + +++ +I D S
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 163 FCXXXXXXXXXXXGR--WTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ C A+N G + A L VL +P + + +L+ ++
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIK--AGDVF-------ALTANAE 258
T ++ C G P P + WFKD + IK + F AL +
Sbjct: 147 ERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESS 206
Query: 259 DPTSLGTYTCEAVNCMGRAYSS 280
+ T G Y C A N G YSS
Sbjct: 207 EETDQGKYECVATNSAGVRYSS 228
>BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein.
Length = 227
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 82 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 139
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 140 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 199
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 200 SLGEATCTAELIV 212
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 117 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 176
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 177 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 220
>BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 8 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 65
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 66 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 125
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 126 SLGEATCTAELIV 138
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 146
>BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 8 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 65
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 66 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 125
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 126 SLGEATCTAELIV 138
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 146
>BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein.
Length = 236
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 81 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 138
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 139 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 198
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 199 SLGEATCTAELIV 211
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 116 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 175
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 176 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 219
>AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein
isoform 1 protein.
Length = 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 8 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 65
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 66 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 125
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 126 SLGEATCTAELIV 138
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 146
>AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein
protein.
Length = 153
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 8 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 65
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 66 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 125
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 126 SLGEATCTAELIV 138
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 146
>AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle
myosin light chain kinase protein.
Length = 300
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 68 TARTGDTGVYT--LQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
+ R TG T L A D ++ LE AEE P + P F + ++DL V G+
Sbjct: 155 SGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAA 212
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAEN 184
RF +I + +V W+++++ + E+ I D C ++TC A N
Sbjct: 213 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 272
Query: 185 VGGRASCSAHLNV 197
G A+C+A L V
Sbjct: 273 SLGEATCTAELIV 285
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 190 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 249
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 250 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 293
>AB046776-1|BAB13382.1| 1596|Homo sapiens KIAA1556 protein protein.
Length = 1596
Score = 53.2 bits (122), Expect = 1e-06
Identities = 57/226 (25%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 67 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 125
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 126 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 183
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 184 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 236
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
G LT +A + TYTC+ +G+A S +++ V GR
Sbjct: 237 QPSQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGR 278
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 23/199 (11%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
+ E +L ++ A D+G Y +A A S RV P F L+
Sbjct: 419 SHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHAR-----------PVRFQEALK 467
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
DL V G ++SS V W L ++ S+ ++G+
Sbjct: 468 DLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDS 526
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR-ALLTEQGTVSLECKVVGVPTP 234
GR++C+ G + SA L V A +F+ +LR TE T +L C+ + P
Sbjct: 527 GRYSCSF----GDQTTSATLTVTALPA----QFIGKLRNKEATEGATATLRCE-LSKAAP 577
Query: 235 VLRWFKDSREIKAGDVFAL 253
V W K S ++ GD + L
Sbjct: 578 V-EWRKGSETLRDGDRYCL 595
Score = 36.3 bits (80), Expect = 0.16
Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 13/148 (8%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ L++ G E+ S V W + L + +R S+ +DGS
Sbjct: 988 PSKFIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 1045
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V A F+E+++ +G T L+
Sbjct: 1046 IRGLAVVDAGEYSC----VCGQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 1097
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDVFAL 253
C+ + PV W K S ++ GD ++L
Sbjct: 1098 CE-LSKAAPV-EWRKGSETLRGGDRYSL 1123
Score = 34.3 bits (75), Expect = 0.66
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 24/204 (11%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ +E + L V R D+G Y S + G T L V+A P F
Sbjct: 503 DKYSLRQEGAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTAL-------PAQF 551
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ +L++ G E+ S V W + L + +R + +DG+
Sbjct: 552 IGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGL 609
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
++C V G SA L + A+ F+ LR + +G T +L C+ +
Sbjct: 610 AMVDAAEYSC----VCGEERTSASLTIRPMPAH----FIGRLRHQESIEGATATLRCE-L 660
Query: 230 GVPTPVLRWFKDSREIKAGDVFAL 253
PV W K ++ GD +L
Sbjct: 661 SKAAPV-EWRKGRESLRDGDRHSL 683
Score = 31.1 bits (67), Expect = 6.1
Identities = 61/246 (24%), Positives = 88/246 (35%), Gaps = 33/246 (13%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
++E +RLT+S D+ YT G +R +L V ED L+
Sbjct: 239 SQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGRRVHIIED-------LE 287
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI-VRDGSFFCXXXXXXXXXX 174
D+ V+ G+ F I + V W+ ++ L E I + G +
Sbjct: 288 DVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKD 347
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G T E RAS + + P + R E A +TE ++L C+ P
Sbjct: 348 SG--TIYFEAGDQRASAALRVTE-KPSVFSR----ELTDATITEGEDLTLVCETSTCDIP 400
Query: 235 VLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
V W KD + ++ G L G Y CEA G A SSS V V
Sbjct: 401 VC-WTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 455
Query: 286 VGRASR 291
R R
Sbjct: 456 HARPVR 461
>AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 262
Score = 52.8 bits (121), Expect = 2e-06
Identities = 48/204 (23%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + +++ ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV-SSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHVVGRAS 290
C A N G YS+ + ++V G A+
Sbjct: 207 CVATNSAGTRYSAPANLYVRGLAA 230
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor
variant protein.
Length = 1478
Score = 52.4 bits (120), Expect = 2e-06
Identities = 61/254 (24%), Positives = 103/254 (40%), Gaps = 19/254 (7%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 32 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 91
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYRNERRLLEAE-- 152
E+ P G PT Q L V TRT ++ S + ++TW+++ + +
Sbjct: 92 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 148
Query: 153 -RVSIVRDGSF---FCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKR-- 205
R+ +R G G++ C A N G R S A+L V + +R
Sbjct: 149 GRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVP 208
Query: 206 PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---EDPT 261
P F + + G+V++ C VG P P ++W + ++ D + N D
Sbjct: 209 PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVR 268
Query: 262 SLGTYTCEAVNCMG 275
YTC A++ +G
Sbjct: 269 QSANYTCVAMSTLG 282
>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
protein.
Length = 1484
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/213 (23%), Positives = 93/213 (43%), Gaps = 20/213 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + +++ ++R ++ DG+
Sbjct: 49 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV-SSQRFEVIEFDDGA 107
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 108 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 166
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 167 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 226
Query: 268 CEAVNCMGRAYSS-SKVHV-VGRASREGSLKPN 298
C A N G YS+ + ++V V R + S+ P+
Sbjct: 227 CVATNSAGTRYSAPANLYVRVRRVAPRFSIPPS 259
>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
delta protein.
Length = 1912
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine
phosphatase receptor type F protein.
Length = 262
Score = 52.0 bits (119), Expect = 3e-06
Identities = 48/204 (23%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + +++ ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV-SSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGGINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD---------SREIKAGDVFALTANAEDPTSLGTYT 267
+ T ++ C G P P + WFKD + IK AL + + + G Y
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYE 206
Query: 268 CEAVNCMGRAYSS-SKVHVVGRAS 290
C A N G YS+ + ++V G A+
Sbjct: 207 CVATNSAGTRYSAPANLYVRGLAA 230
>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
Length = 1506
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 52.0 bits (119), Expect = 3e-06
Identities = 57/264 (21%), Positives = 106/264 (40%), Gaps = 19/264 (7%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
D++++ ++++ +LT+ D Y A N AG A + L+V A+ + + T
Sbjct: 260 DEKYIFSDDSS--QLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQT 317
Query: 110 FLRRLQDLTVKV--------GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
+ + +T+ R ISS E K +W R E++ + +
Sbjct: 318 AMELEEQVTLTCEASGDPIPSITWRTSTRNISSEE-KASWTRPEKQETLDGHMVVRSHAR 376
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
G + CTA N G+ S S +L V + P A+ T +G
Sbjct: 377 VSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV------AVYTWEGN 430
Query: 222 -VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
V++ C+V P+ + WF+D + + + + + S T ++ N G Y+
Sbjct: 431 QVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN-YNC 489
Query: 281 SKVHVVGRASREGSLKPNSSGLSP 304
+ V+ +G+ S E L + SP
Sbjct: 490 TAVNRIGQESLEFILVQADTPSSP 513
Score = 35.5 bits (78), Expect = 0.28
Identities = 34/152 (22%), Positives = 57/152 (37%), Gaps = 11/152 (7%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+ +LD V A LT+ + + D G Y ASN G D+ + LEV +
Sbjct: 357 TRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV--QY 414
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA--ERVSIVR 158
+P + P + G + E+ + ++W+R+ + L + + I
Sbjct: 415 APKLQGPVA-------VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYN 467
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRAS 190
S G + CTA N G+ S
Sbjct: 468 TPSASYLEVTPDSENDFGNYNCTAVNRIGQES 499
Score = 31.5 bits (68), Expect = 4.6
Identities = 37/187 (19%), Positives = 71/187 (37%), Gaps = 16/187 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDT-ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
LT+ A D G+Y + GS++ A V +++ + P R +D +
Sbjct: 81 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI--- 137
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVS-IVRDGSFFCXXXXXXXXXXXGRWTCT 181
+ +++SS + W R ++ + V IV ++ G + C
Sbjct: 138 -----VCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYL--QIRGIKKTDEGTYRCE 190
Query: 182 AENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
+ + V+V P + + + A L + +V+L C G P P + W
Sbjct: 191 GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQ--SVTLVCDAEGFPEPTMSWT 248
Query: 240 KDSREIK 246
KD +I+
Sbjct: 249 KDGEQIE 255
>BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein.
Length = 601
Score = 52.0 bits (119), Expect = 3e-06
Identities = 57/264 (21%), Positives = 106/264 (40%), Gaps = 19/264 (7%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
D++++ ++++ +LT+ D Y A N AG A + L+V A+ + + T
Sbjct: 3 DEKYIFSDDSS--QLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQT 60
Query: 110 FLRRLQDLTVKV--------GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
+ + +T+ R ISS E K +W R E++ + +
Sbjct: 61 AMELEEQVTLTCEASGDPIPSITWRTSTRNISSEE-KASWTRPEKQETLDGHMVVRSHAR 119
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT 221
G + CTA N G+ S S +L V + P A+ T +G
Sbjct: 120 VSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV------AVYTWEGN 173
Query: 222 -VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
V++ C+V P+ + WF+D + + + + + S T ++ N G Y+
Sbjct: 174 QVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN-YNC 232
Query: 281 SKVHVVGRASREGSLKPNSSGLSP 304
+ V+ +G+ S E L + SP
Sbjct: 233 TAVNRIGQESLEFILVQADTPSSP 256
Score = 35.5 bits (78), Expect = 0.28
Identities = 34/152 (22%), Positives = 57/152 (37%), Gaps = 11/152 (7%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T+ +LD V A LT+ + + D G Y ASN G D+ + LEV +
Sbjct: 100 TRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV--QY 157
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA--ERVSIVR 158
+P + P + G + E+ + ++W+R+ + L + + I
Sbjct: 158 APKLQGPVA-------VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYN 210
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRAS 190
S G + CTA N G+ S
Sbjct: 211 TPSASYLEVTPDSENDFGNYNCTAVNRIGQES 242
>AY302131-1|AAP59845.1| 593|Homo sapiens NEPH1 protein protein.
Length = 593
Score = 52.0 bits (119), Expect = 3e-06
Identities = 79/305 (25%), Positives = 115/305 (37%), Gaps = 48/305 (15%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
R V + +AG L ++ A D Y QA+ AA + R +L V +PPT
Sbjct: 12 RVVGSADAGQYNLEITDAELSDDASYECQATEAA-LRSRRAKLTVL--------NPPTVT 62
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECK-VTWYRNERRLLEAE--RVSIVRDGSFFCXXXX 168
++ TV+ G R F + ++ E W + + +A R D SFF
Sbjct: 63 LSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPV- 121
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECK 227
+C N G + S +NV + P V + + T+ G+ V+L C
Sbjct: 122 ----------SCEVHNKVGSTNVSTLVNV-----HFAPRIVVDPKPTTTDIGSDVTLTCV 166
Query: 228 VVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
VG P L W K + + L + GTYTC A+ V +G
Sbjct: 167 WVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAI-----------VPRIG 215
Query: 288 RASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
A RE L N PPI + E QY + + C I P P + W KE
Sbjct: 216 VAEREVPLYVNG-------PPIISSEAV-QYAVRGDGGKVECFIGSTPPPDRIAWAWKEN 267
Query: 348 KVEAG 352
+E G
Sbjct: 268 FLEVG 272
>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>AL139010-2|CAH73882.1| 593|Homo sapiens kin of IRRE like
(Drosophila) protein.
Length = 593
Score = 52.0 bits (119), Expect = 3e-06
Identities = 79/305 (25%), Positives = 115/305 (37%), Gaps = 48/305 (15%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFL 111
R V + +AG L ++ A D Y QA+ AA + R +L V +PPT
Sbjct: 12 RVVGSADAGQYNLEITDAELSDDASYECQATEAA-LRSRRAKLTVL--------NPPTVT 62
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECK-VTWYRNERRLLEAE--RVSIVRDGSFFCXXXX 168
++ TV+ G R F + ++ E W + + +A R D SFF
Sbjct: 63 LSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPV- 121
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECK 227
+C N G + S +NV + P V + + T+ G+ V+L C
Sbjct: 122 ----------SCEVHNKVGSTNVSTLVNV-----HFAPRIVVDPKPTTTDIGSDVTLTCV 166
Query: 228 VVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVG 287
VG P L W K + + L + GTYTC A+ V +G
Sbjct: 167 WVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAI-----------VPRIG 215
Query: 288 RASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
A RE L N PPI + E QY + + C I P P + W KE
Sbjct: 216 VAEREVPLYVNG-------PPIISSEAV-QYAVRGDGGKVECFIGSTPPPDRIAWAWKEN 267
Query: 348 KVEAG 352
+E G
Sbjct: 268 FLEVG 272
>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
Length = 1040
Score = 52.0 bits (119), Expect = 3e-06
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)
Query: 206 PEFVEELRALLTEQGT--VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTAN------- 256
P+ VEELR L GT + KV G P P L WFKD + + A +T
Sbjct: 832 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 891
Query: 257 --AEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTREL 314
+ G Y N MG AYSS+++ V R E KP S PP
Sbjct: 892 IISVTREDSGQYAAYISNAMGAAYSSARLLV--RGPDEPEEKPASDVHEQLVPPRMLERF 949
Query: 315 EDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+ V+ T S ++ P P +V W +E +
Sbjct: 950 TPKKVKKGSSITFSVKVEGRPVP-TVHWLREEAE 982
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED----- 259
P F+ EL+ + G VS +C V G P P +RWFKD + ++ D + + + +
Sbjct: 697 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 756
Query: 260 -----PTSLGTYTCEAVNCMGRAYSSSKVHV 285
P +G Y C A N MG + + +++ V
Sbjct: 757 ITAVVPADMGVYRCLAENSMGVSSTKAELRV 787
Score = 44.4 bits (100), Expect = 6e-04
Identities = 41/149 (27%), Positives = 58/149 (38%), Gaps = 15/149 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSA----EESPSGED-----PPTFLRRL 114
L + + D+G Y SNA G+ + RL V EE P+ + PP L R
Sbjct: 890 LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERF 949
Query: 115 QDLTVKVGTRTRFLVEIISSTECKVTWYRNE--RRLL----EAERVSIVRDGSFFCXXXX 168
VK G+ F V++ V W R E R +L + ++
Sbjct: 950 TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLL 1009
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAHLNV 197
G +TC A N G+A CSA L+V
Sbjct: 1010 DVGRQHQGTYTCIASNAAGQALCSASLHV 1038
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/223 (22%), Positives = 83/223 (37%), Gaps = 30/223 (13%)
Query: 95 EVSAEESPSGEDP-PTFLRRLQDLTVKVGTR-TRFLVEIISSTECKVTWYRNERRLLEAE 152
E ES + E P + L+DL V GTR +F +++ ++ W+++ + L +
Sbjct: 818 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 877
Query: 153 RVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKR------- 205
+ + G++ N G A SA L V P +
Sbjct: 878 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVH 937
Query: 206 -----PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA--------GDVF 251
P +E ++G+ ++ KV G P P + W ++ E G
Sbjct: 938 EQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 997
Query: 252 ALTANAEDPTSL-------GTYTCEAVNCMGRAYSSSKVHVVG 287
A +A L GTYTC A N G+A S+ +HV G
Sbjct: 998 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSG 1040
Score = 34.7 bits (76), Expect = 0.50
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKV 349
+P S L+ + P+F EL++Q V+ P + C + P P SV W+ K+GK+
Sbjct: 685 EPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMP-SVRWF-KDGKL 736
Score = 30.7 bits (66), Expect = 8.1
Identities = 30/118 (25%), Positives = 43/118 (36%), Gaps = 2/118 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRD-GSFFCXX 166
P FL LQ+ V+ G F + V W+++ + L E + I D
Sbjct: 697 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 756
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQGTVS 223
G + C AEN G +S A L V L Y E + + QG +S
Sbjct: 757 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 814
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 50 DDRF-VSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV 96
DD + ++ ++ GG +L ++ D GVY A N+ G + + L V
Sbjct: 740 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 787
>AJ314905-1|CAC85752.1| 2212|Homo sapiens obscurin protein.
Length = 2212
Score = 52.0 bits (119), Expect = 3e-06
Identities = 55/228 (24%), Positives = 88/228 (38%), Gaps = 28/228 (12%)
Query: 77 YTLQASNAAGSDTARVRLEVSAEESPSG----EDPPTFLRRLQDLTVKVGTRTRFLVEII 132
Y L AA SD V V S + E P ++ L+D V G E+
Sbjct: 59 YILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL- 117
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
S V W ++ + + ++++ +V +G+ G +TC E +++ S
Sbjct: 118 SRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTAS 175
Query: 193 AHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVLRWFKDSREIKA---- 247
H+ K F EEL L + E+GT CK P + W K E++A
Sbjct: 176 LHVE------EKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTWRKGLLELRASGKH 228
Query: 248 -----GDVFALTANAEDPTSLGTYTCEAVNCMGRA----YSSSKVHVV 286
G LT +A + TYTC+ RA + +VH++
Sbjct: 229 QPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQAGRRVHII 276
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 23/199 (11%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
+ E +L ++ A D+G Y +A A S RV P F L+
Sbjct: 412 SHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHAR-----------PVRFQEALK 460
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
DL V G ++SS V W L ++ S+ ++G+
Sbjct: 461 DLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDS 519
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELR-ALLTEQGTVSLECKVVGVPTP 234
GR++C+ G + SA L V A +F+ +LR TE T +L C+ + P
Sbjct: 520 GRYSCSF----GDQTTSATLTVTALPA----QFIGKLRNKEATEGATATLRCE-LSKAAP 570
Query: 235 VLRWFKDSREIKAGDVFAL 253
V W K S ++ GD + L
Sbjct: 571 V-EWRKGSETLRDGDRYCL 588
Score = 41.1 bits (92), Expect = 0.006
Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 11/133 (8%)
Query: 117 LTVKVGTR-TRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXX 175
LT++ T +++ S V W + L + +R ++ +DG+
Sbjct: 1591 LTIREATEGATAMLQCELSKVAPVEWRKGPETLRDGDRYNLRQDGTRCELQIHGLSVADT 1650
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTP 234
G ++C V G+ SA L V P+ P F E L++L E+G T +L+C+ + PT
Sbjct: 1651 GEYSC----VCGQEKTSATLTVKAPQ----PVFREPLQSLQAEEGSTATLQCE-LSEPTA 1701
Query: 235 VLRWFKDSREIKA 247
+ W K +++A
Sbjct: 1702 TVVWSKGGLQLQA 1714
Score = 36.3 bits (80), Expect = 0.16
Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 13/148 (8%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXX 166
P F+ L++ G E+ S V W + L + +R S+ +DGS
Sbjct: 981 PSKFIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 1038
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLE 225
G ++C V G+ SA L V A F+E+++ +G T L+
Sbjct: 1039 IRGLAVVDAGEYSC----VCGQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 1090
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDVFAL 253
C+ + PV W K S ++ GD ++L
Sbjct: 1091 CE-LSKAAPV-EWRKGSETLRGGDRYSL 1116
Score = 34.3 bits (75), Expect = 0.66
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 24/204 (11%)
Query: 51 DRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTF 110
D++ +E + L V R D+G Y S + G T L V+A P F
Sbjct: 496 DKYSLRQEGAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTAL-------PAQF 544
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
+ +L++ G E+ S V W + L + +R + +DG+
Sbjct: 545 IGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGL 602
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVV 229
++C V G SA L + A+ F+ LR + +G T +L C+ +
Sbjct: 603 AMVDAAEYSC----VCGEERTSASLTIRPMPAH----FIGRLRHQESIEGATATLRCE-L 653
Query: 230 GVPTPVLRWFKDSREIKAGDVFAL 253
PV W K ++ GD +L
Sbjct: 654 SKAAPV-EWRKGRESLRDGDRHSL 676
Score = 30.7 bits (66), Expect = 8.1
Identities = 60/246 (24%), Positives = 88/246 (35%), Gaps = 32/246 (13%)
Query: 56 TEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQ 115
++E +RLT+S D+ YT G +R +L V A + L+
Sbjct: 231 SQEGLTLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQAGRRVH------IIEDLE 280
Query: 116 DLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI-VRDGSFFCXXXXXXXXXX 174
D+ V+ G+ F I + V W+ ++ L E I + G +
Sbjct: 281 DVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKD 340
Query: 175 XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTP 234
G T E RAS + + P + R E A +TE ++L C+ P
Sbjct: 341 SG--TIYFEAGDQRASAALRVTE-KPSVFSR----ELTDATITEGEDLTLVCETSTCDIP 393
Query: 235 VLRWFKDSREIKA---------GDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
V W KD + ++ G L G Y CEA G A SSS V V
Sbjct: 394 VC-WTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 448
Query: 286 VGRASR 291
R R
Sbjct: 449 HARPVR 454
>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine
phosphatase receptor type D protein.
Length = 1912
Score = 52.0 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 101/257 (39%), Gaps = 22/257 (8%)
Query: 38 ILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTG-DTGVYTLQASNAAGSDTARVRLEV 96
+ N K + ++ + ++ G L + RT D +Y ASN G + RL V
Sbjct: 56 VWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 115
Query: 97 SAEES-PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISST-ECKVTWYR---------NE 145
E+ P G PT Q L V TRT ++ S + ++TW++ N
Sbjct: 116 LREDQIPRGF--PTIDMGPQ-LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNN 172
Query: 146 RRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYK 204
R+ + SI G++ C A N G R S A+L V + +
Sbjct: 173 GRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVR 232
Query: 205 R--PEF-VEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANA---E 258
R P F + + G+V++ C VG P P ++W + ++ D + N
Sbjct: 233 RVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELN 292
Query: 259 DPTSLGTYTCEAVNCMG 275
D YTC A++ +G
Sbjct: 293 DVRQSANYTCVAMSTLG 309
Score = 43.6 bits (98), Expect = 0.001
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 9/144 (6%)
Query: 105 EDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS- 161
E PP F R D T G F+ + K+ W + ++ + +R ++ DGS
Sbjct: 21 ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEVIEFDDGSG 79
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALLT 217
+ C A N G S S L VL +P+ + + +L+ ++
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLK-VVE 138
Query: 218 EQGTVSLECKVVGVPTPVLRWFKD 241
T ++ C G P P + WFKD
Sbjct: 139 RTRTATMLCAASGNPDPEITWFKD 162
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 16/232 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTAR-VRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
L ++ R D G++ ASN A + RL VS S + ++P L ++LT+ V
Sbjct: 194 LQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEP-AILVGPENLTLTVH 252
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
+ V+W R + R + E + ++ G+ G + C A
Sbjct: 253 QTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHS---GVYVCAA 309
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKD 241
G R +A ++V EFV+ +++ GT ++ C+ G P P + W K+
Sbjct: 310 NRPGTRVRRTAQGRLVVQAP---AEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKN 366
Query: 242 SREIKAG-------DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ + G + LT + P Y C A N G + +S+++ V+
Sbjct: 367 GQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418
Score = 39.5 bits (88), Expect = 0.018
Identities = 54/207 (26%), Positives = 79/207 (38%), Gaps = 14/207 (6%)
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
G RF +I + +TW +N + + ER +++ G G + C
Sbjct: 153 GGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVL---QITGLRAEDGGIFHC 209
Query: 181 TAENVGG-RASCSAHLNVLVPK--AYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVL 236
A N+ R S A L V AYK P + L LT T LEC G P P++
Sbjct: 210 VASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIV 269
Query: 237 RWFK-DSREIKAGDVFAL-TAN--AEDPT--SLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W + D R I + L T N D T G Y C A R +++ +V +A
Sbjct: 270 SWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAP 329
Query: 291 REGSLKPNSSGLSPEPPPIFTRELEDQ 317
E P S +FT + + +
Sbjct: 330 AEFVQHPQSISRPAGTTAMFTCQAQGE 356
Score = 32.7 bits (71), Expect = 2.0
Identities = 25/108 (23%), Positives = 49/108 (45%), Gaps = 8/108 (7%)
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX---XXXXXGRWTCTAENVGGRASCSAH 194
++TW +N L E+ +++ +GS G + C A+N G S
Sbjct: 72 RITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLV-VSRK 130
Query: 195 LNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD 241
+ +A +F +A + E+G V+ +C++ G+P P++ W K+
Sbjct: 131 ARI---QAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKN 175
>BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein.
Length = 353
Score = 51.6 bits (118), Expect = 4e-06
Identities = 54/232 (23%), Positives = 101/232 (43%), Gaps = 30/232 (12%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + +++ ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV-SSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD------------SREIKAGDV---FALTANAEDPT 261
+ T ++ C G P P + WFKD +++++G AL + + +
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEES 206
Query: 262 SLGTYTCEAVNCMGRAYSS-SKVHVVGRASREG-SLKPNS----SGLSPEPP 307
G Y C A N G YS+ + ++V G+ S L P S +GLS + P
Sbjct: 207 DQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSP 258
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 16/232 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTAR-VRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
L ++ R D G++ ASN A + RL VS S + ++P L ++LT+ V
Sbjct: 194 LQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEP-AILVGPENLTLTVH 252
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
+ V+W R + R + E + ++ G+ G + C A
Sbjct: 253 QTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHS---GVYVCAA 309
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSL-ECKVVGVPTPVLRWFKD 241
G R +A ++V EFV+ +++ GT ++ C+ G P P + W K+
Sbjct: 310 NRPGTRVRRTAQGRLVVQAP---AEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKN 366
Query: 242 SREIKAG-------DVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ + G + LT + P Y C A N G + +S+++ V+
Sbjct: 367 GQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418
Score = 39.5 bits (88), Expect = 0.018
Identities = 54/207 (26%), Positives = 79/207 (38%), Gaps = 14/207 (6%)
Query: 122 GTRTRFLVEIISSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
G RF +I + +TW +N + + ER +++ G G + C
Sbjct: 153 GGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVL---QITGLRAEDGGIFHC 209
Query: 181 TAENVGG-RASCSAHLNVLVPK--AYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTPVL 236
A N+ R S A L V AYK P + L LT T LEC G P P++
Sbjct: 210 VASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIV 269
Query: 237 RWFK-DSREIKAGDVFAL-TAN--AEDPT--SLGTYTCEAVNCMGRAYSSSKVHVVGRAS 290
W + D R I + L T N D T G Y C A R +++ +V +A
Sbjct: 270 SWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAP 329
Query: 291 REGSLKPNSSGLSPEPPPIFTRELEDQ 317
E P S +FT + + +
Sbjct: 330 AEFVQHPQSISRPAGTTAMFTCQAQGE 356
Score = 32.7 bits (71), Expect = 2.0
Identities = 25/108 (23%), Positives = 49/108 (45%), Gaps = 8/108 (7%)
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX---XXXXXGRWTCTAENVGGRASCSAH 194
++TW +N L E+ +++ +GS G + C A+N G S
Sbjct: 72 RITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLV-VSRK 130
Query: 195 LNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKD 241
+ +A +F +A + E+G V+ +C++ G+P P++ W K+
Sbjct: 131 ARI---QAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKN 175
>AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 353
Score = 51.6 bits (118), Expect = 4e-06
Identities = 54/232 (23%), Positives = 101/232 (43%), Gaps = 30/232 (12%)
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR--DGS 161
G+ P F++ +D T G F+ + + ++TW + +++ ++R ++ DG+
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV-SSQRFEVIEFDDGA 87
Query: 162 -FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL----VPKAYKRPEFVEELRALL 216
+ CTA N G + SA L+VL +P + + +L+ ++
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLK-VV 146
Query: 217 TEQGTVSLECKVVGVPTPVLRWFKD------------SREIKAGDV---FALTANAEDPT 261
+ T ++ C G P P + WFKD +++++G AL + + +
Sbjct: 147 EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEES 206
Query: 262 SLGTYTCEAVNCMGRAYSS-SKVHVVGRASREG-SLKPNS----SGLSPEPP 307
G Y C A N G YS+ + ++V G+ S L P S +GLS + P
Sbjct: 207 DQGKYECVATNSAGTRYSAPANLYVRGKDSGSAWPLSPQSCAAPAGLSAQSP 258
>AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens
cDNA FLJ39139 fis, clone NTONG2009229. ).
Length = 410
Score = 51.6 bits (118), Expect = 4e-06
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREI----------KAGDVFALT 254
P F+++ R+ +G+ V LEC+V G PTP +RWF + +E+ + GD+ L
Sbjct: 148 PRFIQKPRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 207
Query: 255 ANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASRE 292
G YTC A N G +S++V + G +S +
Sbjct: 208 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD 245
Score = 34.7 bits (76), Expect = 0.50
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 202 AYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVFAL 253
AY P F +EL+ +G V LEC+V G P +WF+ EI+ F +
Sbjct: 314 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQDQWFRQGSEIQDSPDFRI 366
Score = 30.7 bits (66), Expect = 8.1
Identities = 19/89 (21%), Positives = 33/89 (37%), Gaps = 1/89 (1%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSI-VRDGSFFCXX 166
P F+++ + V G+R + + +V W+ + L + I G
Sbjct: 148 PRFIQKPRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 207
Query: 167 XXXXXXXXXGRWTCTAENVGGRASCSAHL 195
GR+TC A N G + SA +
Sbjct: 208 IAEAFEDDTGRYTCLATNPSGSDTTSAEV 236
>AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein
protein.
Length = 1232
Score = 51.2 bits (117), Expect = 5e-06
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+ A D G+ T + G + L +S E S D P F+ + + + G
Sbjct: 903 LTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS----DAPAFISQPRSQNINEGQ 958
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F EI ++ W++N + + VSI R + + G++T A+
Sbjct: 959 NVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAK 1018
Query: 184 NVGGRASCSAHLNVL 198
N G+ S +A L VL
Sbjct: 1019 NFRGQCSATASLMVL 1033
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 13/180 (7%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+++ G R I +T+ K W N L +E GS G
Sbjct: 857 MSINEGQRLVLKANIAGATDAK--WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 914
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV 235
TC ++ G C L L + P F+ + R+ +G V C++ G P+P
Sbjct: 915 ILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE 973
Query: 236 LRWFKDSREI---------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ WFK++ I ++ +V++L + G YT +A N G+ +++ + V+
Sbjct: 974 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 1033
Score = 41.5 bits (93), Expect = 0.004
Identities = 26/120 (21%), Positives = 43/120 (35%), Gaps = 4/120 (3%)
Query: 82 SNAAGSDTARVRLEVSAEESPSGEDP----PTFLRRLQDLTVKVGTRTRFLVEIISSTEC 137
S SD V+ + P +P P + LQD TV + +F V+
Sbjct: 631 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 690
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
W ++ + + + + + D F G +TCT +N G S S L +
Sbjct: 691 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 750
Score = 41.1 bits (92), Expect = 0.006
Identities = 25/109 (22%), Positives = 43/109 (39%)
Query: 89 TARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL 148
T+ + EV +++ + + P R++ V G TRF++ + S +V WY N L
Sbjct: 164 TSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL 223
Query: 149 LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
E+ ++ G + N G AS A L+V
Sbjct: 224 QESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272
Score = 39.1 bits (87), Expect = 0.023
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
TK + ++ +E+ GG L + T D+G+YT N+AGS ++ +L + A +
Sbjct: 695 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 754
Query: 101 SPSGEDPPTFLRRLQDLT--VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIV 157
+ T ++ ++T K + + + S E K++ +++ +L E S V
Sbjct: 755 DTEAQKVST--QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 811
Score = 35.1 bits (77), Expect = 0.38
Identities = 29/128 (22%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 205 RPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANA------ 257
+P V L+ +V+ K G P P W KD + I G + L+ +
Sbjct: 660 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 719
Query: 258 ---EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS--LKPNSSGLSPEPPPIFTR 312
D + G YTC N G SS K+ + E +S ++P+ +
Sbjct: 720 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 779
Query: 313 ELEDQYVR 320
E+ + +R
Sbjct: 780 EISQKALR 787
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 50.8 bits (116), Expect = 7e-06
Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 23/232 (9%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G Y +N GS+ ++ + +++ E PS FL+ DLT++ G R
Sbjct: 574 DEGKYQCIVTNHFGSNYSQ-KAKLTVNEMPS------FLKTPMDLTIRTGAMARLECAAE 626
Query: 133 SSTECKVTWYRNERRLLEA---ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRA 189
+++W ++ A R+ ++ + F G ++C A+N G
Sbjct: 627 GHPAPQISWQKDGGTDFPAARERRMHVMPEDDVF--FIANVKIEDMGIYSCMAQNTAGGL 684
Query: 190 SCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD 249
S +A L VL ++ RP +E+ +T T L+C G P P L W KD + +
Sbjct: 685 SANASLTVLETPSFIRP--LED--KTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTE 740
Query: 250 -VFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
F AN G YTC N +G ++V+ + + S
Sbjct: 741 RHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSS 792
Score = 39.5 bits (88), Expect = 0.018
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D G+Y+ A N AG +A L V + P+F+R L+D TV G
Sbjct: 662 IANVKIEDMGIYSCMAQNTAGGLSANASLTVL--------ETPSFIRPLEDKTVTRGETA 713
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
S ++ W +++ LL ER G++TC N
Sbjct: 714 VLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLL--IIVDAGLEDAGKYTCIMSNT 771
Query: 186 GGRASCSAHLNVL 198
G +LNV+
Sbjct: 772 LGTERGHIYLNVI 784
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 50.8 bits (116), Expect = 7e-06
Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 23/232 (9%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G Y +N GS+ ++ + +++ E PS FL+ DLT++ G R
Sbjct: 574 DEGKYQCIVTNHFGSNYSQ-KAKLTVNEMPS------FLKTPMDLTIRTGAMARLECAAE 626
Query: 133 SSTECKVTWYRNERRLLEA---ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRA 189
+++W ++ A R+ ++ + F G ++C A+N G
Sbjct: 627 GHPAPQISWQKDGGTDFPAARERRMHVMPEDDVF--FIANVKIEDMGIYSCMAQNTAGGL 684
Query: 190 SCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD 249
S +A L VL ++ RP +E+ +T T L+C G P P L W KD + +
Sbjct: 685 SANASLTVLETPSFIRP--LED--KTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTE 740
Query: 250 -VFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
F AN G YTC N +G ++V+ + + S
Sbjct: 741 RHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSS 792
Score = 39.5 bits (88), Expect = 0.018
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D G+Y+ A N AG +A L V + P+F+R L+D TV G
Sbjct: 662 IANVKIEDMGIYSCMAQNTAGGLSANASLTVL--------ETPSFIRPLEDKTVTRGETA 713
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
S ++ W +++ LL ER G++TC N
Sbjct: 714 VLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLL--IIVDAGLEDAGKYTCIMSNT 771
Query: 186 GGRASCSAHLNVL 198
G +LNV+
Sbjct: 772 LGTERGHIYLNVI 784
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 50.8 bits (116), Expect = 7e-06
Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 23/232 (9%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G Y +N GS+ ++ + +++ E PS FL+ DLT++ G R
Sbjct: 574 DEGKYQCIVTNHFGSNYSQ-KAKLTVNEMPS------FLKTPMDLTIRTGAMARLECAAE 626
Query: 133 SSTECKVTWYRNERRLLEA---ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRA 189
+++W ++ A R+ ++ + F G ++C A+N G
Sbjct: 627 GHPAPQISWQKDGGTDFPAARERRMHVMPEDDVF--FIANVKIEDMGIYSCMAQNTAGGL 684
Query: 190 SCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD 249
S +A L VL ++ RP +E+ +T T L+C G P P L W KD + +
Sbjct: 685 SANASLTVLETPSFIRP--LED--KTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTE 740
Query: 250 -VFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
F AN G YTC N +G ++V+ + + S
Sbjct: 741 RHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSS 792
Score = 39.5 bits (88), Expect = 0.018
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D G+Y+ A N AG +A L V + P+F+R L+D TV G
Sbjct: 662 IANVKIEDMGIYSCMAQNTAGGLSANASLTVL--------ETPSFIRPLEDKTVTRGETA 713
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
S ++ W +++ LL ER G++TC N
Sbjct: 714 VLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLL--IIVDAGLEDAGKYTCIMSNT 771
Query: 186 GGRASCSAHLNVL 198
G +LNV+
Sbjct: 772 LGTERGHIYLNVI 784
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 50.8 bits (116), Expect = 7e-06
Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 23/232 (9%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G Y +N GS+ ++ + +++ E PS FL+ DLT++ G R
Sbjct: 582 DEGKYQCIVTNHFGSNYSQ-KAKLTVNEMPS------FLKTPMDLTIRTGAMARLECAAE 634
Query: 133 SSTECKVTWYRNERRLLEA---ERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRA 189
+++W ++ A R+ ++ + F G ++C A+N G
Sbjct: 635 GHPAPQISWQKDGGTDFPAARERRMHVMPEDDVF--FIANVKIEDMGIYSCMAQNTAGGL 692
Query: 190 SCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD 249
S +A L VL ++ RP +E+ +T T L+C G P P L W KD + +
Sbjct: 693 SANASLTVLETPSFIRP--LED--KTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTE 748
Query: 250 -VFALTANA------EDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
F AN G YTC N +G ++V+ + + S
Sbjct: 749 RHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSS 800
Score = 39.5 bits (88), Expect = 0.018
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 10/133 (7%)
Query: 66 VSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRT 125
++ + D G+Y+ A N AG +A L V + P+F+R L+D TV G
Sbjct: 670 IANVKIEDMGIYSCMAQNTAGGLSANASLTVL--------ETPSFIRPLEDKTVTRGETA 721
Query: 126 RFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENV 185
S ++ W +++ LL ER G++TC N
Sbjct: 722 VLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLL--IIVDAGLEDAGKYTCIMSNT 779
Query: 186 GGRASCSAHLNVL 198
G +LNV+
Sbjct: 780 LGTERGHIYLNVI 792
>BC125103-1|AAI25104.1| 414|Homo sapiens CADM1 protein protein.
Length = 414
Score = 50.4 bits (115), Expect = 9e-06
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 212 LRALLTEQGTVSLECKVVGVPTPVL-RWFKDSREIKAGDVFA---LTANAEDPTSLGTYT 267
L+ L E + L C+ +G P PV+ W + E+ V + L N + T GTY
Sbjct: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 312
Query: 268 CEAVNCMGRAYSSSKVHVV-GRASREGSLK 296
CEA N +G+A+S ++V RA EGS++
Sbjct: 313 CEASNIVGKAHSDYMLYVYDSRAGEEGSIR 342
>BC125102-1|AAI25103.1| 415|Homo sapiens CADM1 protein protein.
Length = 415
Score = 50.4 bits (115), Expect = 9e-06
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 212 LRALLTEQGTVSLECKVVGVPTPVL-RWFKDSREIKAGDVFA---LTANAEDPTSLGTYT 267
L+ L E + L C+ +G P PV+ W + E+ V + L N + T GTY
Sbjct: 254 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 313
Query: 268 CEAVNCMGRAYSSSKVHVV-GRASREGSLK 296
CEA N +G+A+S ++V RA EGS++
Sbjct: 314 CEASNIVGKAHSDYMLYVYDSRAGEEGSIR 343
>BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1264
Score = 50.4 bits (115), Expect = 9e-06
Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 11/176 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + D+G Y+ A N +G D V V+ E S + LQD V +G
Sbjct: 275 LATDSVDPADSGNYSCMAGNKSG-DVKYVTYMVNVLEHAS------ISKGLQDQIVSLGA 327
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F ++ + TW+ N + + + R +G G + C A+
Sbjct: 328 TVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG----LKISGVTVEDVGMYQCVAD 383
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
N G + L + +K + A + + V+L C G+P PV+RW+
Sbjct: 384 NGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWY 439
Score = 46.8 bits (106), Expect = 1e-04
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-----LTANAEDPTSLGTYTCEAVNCMGR 276
V+LEC V GVP P + W KD ++I G + L ++ DP G Y+C A N G
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGD 298
Query: 277 A-YSSSKVHVVGRAS 290
Y + V+V+ AS
Sbjct: 299 VKYVTYMVNVLEHAS 313
Score = 33.9 bits (74), Expect = 0.87
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 28/181 (15%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G ++C A N G ++ ++ A +++ +L TV C V G P P
Sbjct: 286 GNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSL---GATVHFTCDVHGNPAPN 342
Query: 236 LRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
WF + +R + AG+ L + +G Y C A N +G +S+ ++ +
Sbjct: 343 CTWFHNAQPIHPSARHLTAGN--GLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEI--- 397
Query: 289 ASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+G KP P+ + + +V TLSC P P + WY+ G
Sbjct: 398 -ENDGGFKPVII-----TAPVSAKVADGDFV------TLSCNASGLPVP-VIRWYDSHGL 444
Query: 349 V 349
+
Sbjct: 445 I 445
>BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1287
Score = 50.4 bits (115), Expect = 9e-06
Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 11/176 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + D+G Y+ A N +G D V V+ E S + LQD V +G
Sbjct: 275 LATDSVDPADSGNYSCMAGNKSG-DVKYVTYMVNVLEHAS------ISKGLQDQIVSLGA 327
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F ++ + TW+ N + + + R +G G + C A+
Sbjct: 328 TVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG----LKISGVTVEDVGMYQCVAD 383
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
N G + L + +K + A + + V+L C G+P PV+RW+
Sbjct: 384 NGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWY 439
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-----LTANAEDPTSLGTYTCEAVNCMGR 276
V+LEC V GVP P + W KD ++I + L ++ DP G Y+C A N G
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPESNWRRLYSHLATDSVDPADSGNYSCMAGNKSGD 298
Query: 277 A-YSSSKVHVVGRAS 290
Y + V+V+ AS
Sbjct: 299 VKYVTYMVNVLEHAS 313
Score = 33.9 bits (74), Expect = 0.87
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 28/181 (15%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G ++C A N G ++ ++ A +++ +L TV C V G P P
Sbjct: 286 GNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSL---GATVHFTCDVHGNPAPN 342
Query: 236 LRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
WF + +R + AG+ L + +G Y C A N +G +S+ ++ +
Sbjct: 343 CTWFHNAQPIHPSARHLTAGN--GLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEI--- 397
Query: 289 ASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+G KP P+ + + +V TLSC P P + WY+ G
Sbjct: 398 -ENDGGFKPVII-----TAPVSAKVADGDFV------TLSCNASGLPVP-VIRWYDSHGL 444
Query: 349 V 349
+
Sbjct: 445 I 445
>BC047021-1|AAH47021.1| 387|Homo sapiens CADM1 protein protein.
Length = 387
Score = 50.4 bits (115), Expect = 9e-06
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 212 LRALLTEQGTVSLECKVVGVPTPVL-RWFKDSREIKAGDVFA---LTANAEDPTSLGTYT 267
L+ L E + L C+ +G P PV+ W + E+ V + L N + T GTY
Sbjct: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 312
Query: 268 CEAVNCMGRAYSSSKVHVV-GRASREGSLK 296
CEA N +G+A+S ++V RA EGS++
Sbjct: 313 CEASNIVGKAHSDYMLYVYDSRAGEEGSIR 342
>AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein.
Length = 1264
Score = 50.4 bits (115), Expect = 9e-06
Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 11/176 (6%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + D+G Y+ A N +G D V V+ E S + LQD V +G
Sbjct: 275 LATDSVDPADSGNYSCMAGNKSG-DVEYVTYMVNVLEHAS------ISKGLQDQIVSLGA 327
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F ++ + TW+ N + + + R +G G + C A+
Sbjct: 328 TVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG----LKISGVTVEDVGMYQCVAD 383
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
N G + L + +K + A + + V+L C G+P PV+RW+
Sbjct: 384 NGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWY 439
Score = 46.8 bits (106), Expect = 1e-04
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVFA-----LTANAEDPTSLGTYTCEAVNCMGR 276
V+LEC V GVP P + W KD ++I G + L ++ DP G Y+C A N G
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGD 298
Query: 277 A-YSSSKVHVVGRAS 290
Y + V+V+ AS
Sbjct: 299 VEYVTYMVNVLEHAS 313
Score = 33.9 bits (74), Expect = 0.87
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 28/181 (15%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G ++C A N G ++ ++ A +++ +L TV C V G P P
Sbjct: 286 GNYSCMAGNKSGDVEYVTYMVNVLEHASISKGLQDQIVSL---GATVHFTCDVHGNPAPN 342
Query: 236 LRWFKD-------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
WF + +R + AG+ L + +G Y C A N +G +S+ ++ +
Sbjct: 343 CTWFHNAQPIHPSARHLTAGN--GLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEI--- 397
Query: 289 ASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGK 348
+G KP P+ + + +V TLSC P P + WY+ G
Sbjct: 398 -ENDGGFKPVII-----TAPVSAKVADGDFV------TLSCNASGLPVP-VIRWYDSHGL 444
Query: 349 V 349
+
Sbjct: 445 I 445
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 50.4 bits (115), Expect = 9e-06
Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 27/249 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L + + D G Y A N+ G + AR RL A+ P +++ ++D+ + V
Sbjct: 174 LEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAK--------PHWVQLIKDVEIAVED 225
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ + W +N L+ ER I +G+ G + C AE
Sbjct: 226 SLYWECRASGKPKPSYRWLKNGAALVLEERTQI-ENGAL---TISNLSVTDSGMFQCIAE 281
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEE-LRALLTEQ--GTVSLECKVVGVPTPVLRWFK 240
N G SA L V+ P+F + ++ L+ Q VSL+CK P + W K
Sbjct: 282 NKHGLVYSSAELKVVA----SAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKK 337
Query: 241 DSREIKAGDVFALTANAE------DPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
++ + +L + GTYTC A N G+A + H+V +
Sbjct: 338 GDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKA--NGTTHLVVTEPTRIT 395
Query: 295 LKPNSSGLS 303
L P++ +S
Sbjct: 396 LAPSNMDVS 404
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/159 (26%), Positives = 73/159 (45%), Gaps = 12/159 (7%)
Query: 42 KSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES 101
K+ A L++R T+ G LT+S D+G++ A N G + L+V A
Sbjct: 245 KNGAALVLEER---TQIENGA-LTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAP 300
Query: 102 PSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGS 161
++P +++L + V+VG+ + +S +W + + + E ER+S++ DG
Sbjct: 301 DFSKNP---MKKL--VQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGG 355
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP 200
G +TC AEN G+A+ + HL V P
Sbjct: 356 L---KIANVTKADAGTYTCMAENQFGKANGTTHLVVTEP 391
>X80026-1|CAA56327.1| 588|Homo sapiens B-CAM protein.
Length = 588
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTP 234
G + C E+ + V AY P + E + L L + + C V G+PTP
Sbjct: 333 GTYGCRVEDYDAADDVQLSKTLDVRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTP 392
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEA 270
LRW KDS + G + +L++ D S GTY CEA
Sbjct: 393 ALRWTKDSTPLGDGPMLSLSSITFD--SNGTYVCEA 426
Score = 31.5 bits (68), Expect = 4.6
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 63 RLTVSTARTGDTGVYT-LQASNAAGSDTARVRLEVSAEESPSGEDPPT-FLRRLQDLTVK 120
RL ++ A+ GD Y + + AAG+ A RL V A+ + P L ++D +
Sbjct: 109 RLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQE 168
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRL 148
+ T + K+TWYRN +RL
Sbjct: 169 IATCN----SRNGNPAPKITWYRNGQRL 192
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 49.6 bits (113), Expect = 2e-05
Identities = 55/261 (21%), Positives = 105/261 (40%), Gaps = 23/261 (8%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
D++++ ++++ +LT+ D Y A N AG A + L+V A+ + + T
Sbjct: 260 DEKYIFSDDSS--QLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQT 317
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV----SIVRDGSFFCX 165
+ + +T+ E +TW + R + E+ +VR +
Sbjct: 318 AMELEEQVTLTC--------EASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 369
Query: 166 XXXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VS 223
G + CTA N G+ S S +L V + P A+ T +G V+
Sbjct: 370 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV------AVYTWEGNQVN 423
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ C+V P+ + WF+D + + + + + S T ++ N G Y+ + V
Sbjct: 424 ITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN-YNCTAV 482
Query: 284 HVVGRASREGSLKPNSSGLSP 304
+ +G+ S E L + SP
Sbjct: 483 NRIGQESLEFILVQADTPSSP 503
Score = 34.7 bits (76), Expect = 0.50
Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 11/145 (7%)
Query: 48 SLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP 107
+LD V A LT+ + + D G Y ASN G D+ + LEV + +P + P
Sbjct: 354 TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV--QYAPKLQGP 411
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA--ERVSIVRDGSFFCX 165
+ G + E+ + ++W+R+ + L + + I S
Sbjct: 412 VA-------VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYL 464
Query: 166 XXXXXXXXXXGRWTCTAENVGGRAS 190
G + CTA N G+ S
Sbjct: 465 EVTPDSENDFGNYNCTAVNRIGQES 489
Score = 31.5 bits (68), Expect = 4.6
Identities = 37/187 (19%), Positives = 71/187 (37%), Gaps = 16/187 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDT-ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
LT+ A D G+Y + GS++ A V +++ + P R +D +
Sbjct: 81 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI--- 137
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVS-IVRDGSFFCXXXXXXXXXXXGRWTCT 181
+ +++SS + W R ++ + V IV ++ G + C
Sbjct: 138 -----VCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYL--QIRGIKKTDEGTYRCE 190
Query: 182 AENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
+ + V+V P + + + A L + +V+L C G P P + W
Sbjct: 191 GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQ--SVTLVCDAEGFPEPTMSWT 248
Query: 240 KDSREIK 246
KD +I+
Sbjct: 249 KDGEQIE 255
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 49.6 bits (113), Expect = 2e-05
Identities = 55/261 (21%), Positives = 105/261 (40%), Gaps = 23/261 (8%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
D++++ ++++ +LT+ D Y A N AG A + L+V A+ + + T
Sbjct: 260 DEKYIFSDDSS--QLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQT 317
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV----SIVRDGSFFCX 165
+ + +T+ E +TW + R + E+ +VR +
Sbjct: 318 AMELEEQVTLTC--------EASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 369
Query: 166 XXXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VS 223
G + CTA N G+ S S +L V + P A+ T +G V+
Sbjct: 370 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV------AVYTWEGNQVN 423
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ C+V P+ + WF+D + + + + + S T ++ N G Y+ + V
Sbjct: 424 ITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN-YNCTAV 482
Query: 284 HVVGRASREGSLKPNSSGLSP 304
+ +G+ S E L + SP
Sbjct: 483 NRIGQESLEFILVQADTPSSP 503
Score = 34.7 bits (76), Expect = 0.50
Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 11/145 (7%)
Query: 48 SLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP 107
+LD V A LT+ + + D G Y ASN G D+ + LEV + +P + P
Sbjct: 354 TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV--QYAPKLQGP 411
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA--ERVSIVRDGSFFCX 165
+ G + E+ + ++W+R+ + L + + I S
Sbjct: 412 VA-------VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYL 464
Query: 166 XXXXXXXXXXGRWTCTAENVGGRAS 190
G + CTA N G+ S
Sbjct: 465 EVTPDSENDFGNYNCTAVNRIGQES 489
Score = 31.5 bits (68), Expect = 4.6
Identities = 37/187 (19%), Positives = 71/187 (37%), Gaps = 16/187 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDT-ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
LT+ A D G+Y + GS++ A V +++ + P R +D +
Sbjct: 81 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI--- 137
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVS-IVRDGSFFCXXXXXXXXXXXGRWTCT 181
+ +++SS + W R ++ + V IV ++ G + C
Sbjct: 138 -----VCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYL--QIRGIKKTDEGTYRCE 190
Query: 182 AENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
+ + V+V P + + + A L + +V+L C G P P + W
Sbjct: 191 GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQ--SVTLVCDAEGFPEPTMSWT 248
Query: 240 KDSREIK 246
KD +I+
Sbjct: 249 KDGEQIE 255
>BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein.
Length = 166
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 43 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 100
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 101 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 151
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 56 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 115
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 116 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 159
>BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein.
Length = 167
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 44 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 101
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 102 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 152
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 57 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 116
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 117 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 160
>BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein.
Length = 179
Score = 49.6 bits (113), Expect = 2e-05
Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 8/148 (5%)
Query: 119 VKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
+ G F EI ++ W++N + + VSI R + + G++
Sbjct: 2 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 61
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA-LLTEQGTV-SLECKVVGVPTPVL 236
T A+N G+ S +A L VL + P +E L + + ++G V ++ C G PTP +
Sbjct: 62 TIKAKNFRGQCSATASLMVL-----RIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEV 116
Query: 237 RWFKDSREIKAGDVFAL-TANAEDPTSL 263
W R+I + + N +D T+L
Sbjct: 117 TWSCGGRKIHSQEQGRFHIENTDDLTTL 144
>BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 31 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 147
>BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 31 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 147
>AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein.
Length = 551
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 16/194 (8%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V D G Y+ +A G +L ++ ++ ++ ++ + G
Sbjct: 245 RLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVH----NEVRTEAG 296
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V I G G +TC A
Sbjct: 297 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 355
Query: 183 ENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV-SLECKVVGVPTPVLRWFKD 241
GG+ S HL+V PKA E + R + E G + +L C+V T V W+KD
Sbjct: 356 ---GGQ-RLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQAQTEV-TWYKD 409
Query: 242 SREIKAGDVFALTA 255
+++ + + A
Sbjct: 410 GKKLSSSSKVRMEA 423
Score = 41.1 bits (92), Expect = 0.006
Identities = 48/219 (21%), Positives = 85/219 (38%), Gaps = 27/219 (12%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
RL V A D G Y+ +A S RL ++ + ++ ++ + G
Sbjct: 61 RLVVQQAGKTDAGDYSCEARGQRVS----FRLHITEPKMMFAKEQSVH----NEVQAEAG 112
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
E+ + + +VTWY++ ++L + +V + G G ++C A
Sbjct: 113 ASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 171
Query: 183 ENVGGRASCSAHLNVLVPKAY--KRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
GG+ S HL++ PK K E++A E GT ++ V P + W+K
Sbjct: 172 ---GGQR-VSFHLHITEPKGVFAKEQSVHNEVQA---EAGTTAMLSCEVAQPQTEVTWYK 224
Query: 241 DSREIKA---------GDVFALTANAEDPTSLGTYTCEA 270
D +++ + G L G Y+CEA
Sbjct: 225 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 263
>AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein
isoform 2 protein.
Length = 154
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 31 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 147
>AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein
protein.
Length = 154
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 31 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 147
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 49.6 bits (113), Expect = 2e-05
Identities = 55/261 (21%), Positives = 105/261 (40%), Gaps = 23/261 (8%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
D++++ ++++ +LT+ D Y A N AG A + L+V A+ + + T
Sbjct: 341 DEKYIFSDDSS--QLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQT 398
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV----SIVRDGSFFCX 165
+ + +T+ E +TW + R + E+ +VR +
Sbjct: 399 AMELEEQVTLTC--------EASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 450
Query: 166 XXXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VS 223
G + CTA N G+ S S +L V + P A+ T +G V+
Sbjct: 451 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV------AVYTWEGNQVN 504
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ C+V P+ + WF+D + + + + + S T ++ N G Y+ + V
Sbjct: 505 ITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN-YNCTAV 563
Query: 284 HVVGRASREGSLKPNSSGLSP 304
+ +G+ S E L + SP
Sbjct: 564 NRIGQESLEFILVQADTPSSP 584
Score = 34.7 bits (76), Expect = 0.50
Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 11/145 (7%)
Query: 48 SLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP 107
+LD V A LT+ + + D G Y ASN G D+ + LEV + +P + P
Sbjct: 435 TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV--QYAPKLQGP 492
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA--ERVSIVRDGSFFCX 165
+ G + E+ + ++W+R+ + L + + I S
Sbjct: 493 VA-------VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYL 545
Query: 166 XXXXXXXXXXGRWTCTAENVGGRAS 190
G + CTA N G+ S
Sbjct: 546 EVTPDSENDFGNYNCTAVNRIGQES 570
Score = 31.5 bits (68), Expect = 4.6
Identities = 37/187 (19%), Positives = 71/187 (37%), Gaps = 16/187 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDT-ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVG 122
LT+ A D G+Y + GS++ A V +++ + P R +D +
Sbjct: 162 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI--- 218
Query: 123 TRTRFLVEIISSTECKVTWYRNERRLLEAERVS-IVRDGSFFCXXXXXXXXXXXGRWTCT 181
+ +++SS + W R ++ + V IV ++ G + C
Sbjct: 219 -----VCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYL--QIRGIKKTDEGTYRCE 271
Query: 182 AENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWF 239
+ + V+V P + + + A L + +V+L C G P P + W
Sbjct: 272 GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQ--SVTLVCDAEGFPEPTMSWT 329
Query: 240 KDSREIK 246
KD +I+
Sbjct: 330 KDGEQIE 336
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 869 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 926
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSAHLNV 197
+ E+ I D C ++TC A N G A+C+A L V
Sbjct: 927 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 977
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 882 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 941
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
SL YTC+AVN +G A ++++ V EG
Sbjct: 942 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 985
Score = 44.8 bits (101), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%)
Query: 99 EESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVR 158
+ S S P F ++LQD+ V G + ++ S + W N + L + + + +
Sbjct: 167 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 226
Query: 159 DGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
+GS G + C A+N G+A CS + V
Sbjct: 227 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 265
Score = 39.1 bits (87), Expect = 0.023
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 16/160 (10%)
Query: 206 PEFVEELRALLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKA---------GDVFALTA 255
P F ++L+ + +G + L+C+V P + W + + +K G + +++
Sbjct: 176 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 235
Query: 256 NAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEP--PPIFTRE 313
P G Y C A N G+A S +V V + E + P P+ PP+ E
Sbjct: 236 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 295
Query: 314 LEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
+ + P T + +PP ++ + ++ KV AGE
Sbjct: 296 SDATVKKKPAPKT-PPKAAMPP---QIIQFPEDQKVRAGE 331
Score = 33.5 bits (73), Expect = 1.1
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ AR G YTL N GS A+V L V + P P R LT+
Sbjct: 370 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 428
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/109 (17%), Positives = 41/109 (37%)
Query: 90 ARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLL 149
A V+ + + + P PP ++ +D V+ G ++ + TW + +++
Sbjct: 298 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 357
Query: 150 EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL 198
E+E + + + G +T EN G +L V+
Sbjct: 358 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 406
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 49.2 bits (112), Expect = 2e-05
Identities = 55/261 (21%), Positives = 105/261 (40%), Gaps = 23/261 (8%)
Query: 50 DDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPT 109
D++++ ++++ +LT+ D Y A N AG A + L+V A+ + + T
Sbjct: 260 DEKYIFSDDSS--QLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQT 317
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERV----SIVRDGSFFCX 165
+ + +T+ E +TW + R + E+ +VR +
Sbjct: 318 AMELEEQVTLTC--------EASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 369
Query: 166 XXXXXXXXX-XGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VS 223
G + CTA N G+ S S +L V + P A+ T +G V+
Sbjct: 370 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV------AVYTWEGNQVN 423
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
+ C+V P+ + WF+D + + + + + S T ++ N G Y+ + V
Sbjct: 424 ITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN-YNCTAV 482
Query: 284 HVVGRASREGSLKPNSSGLSP 304
+ +G+ S E L + SP
Sbjct: 483 NRIGQESFEFILVQADTPSSP 503
Score = 34.7 bits (76), Expect = 0.50
Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 11/145 (7%)
Query: 48 SLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP 107
+LD V A LT+ + + D G Y ASN G D+ + LEV + +P + P
Sbjct: 354 TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV--QYAPKLQGP 411
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEA--ERVSIVRDGSFFCX 165
+ G + E+ + ++W+R+ + L + + I S
Sbjct: 412 VA-------VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYL 464
Query: 166 XXXXXXXXXXGRWTCTAENVGGRAS 190
G + CTA N G+ S
Sbjct: 465 EVTPDSENDFGNYNCTAVNRIGQES 489
>X83425-1|CAA58449.1| 628|Homo sapiens Lutheran blood group
glycoprotein protein.
Length = 628
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTP 234
G + C E+ + + AY P + E + L L + + C V G+PTP
Sbjct: 333 GTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTP 392
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEA 270
LRW KDS + G + +L++ D S GTY CEA
Sbjct: 393 ALRWTKDSTPLGDGPMLSLSSITFD--SNGTYVCEA 426
Score = 31.5 bits (68), Expect = 4.6
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 63 RLTVSTARTGDTGVYT-LQASNAAGSDTARVRLEVSAEESPSGEDPPT-FLRRLQDLTVK 120
RL ++ A+ GD Y + + AAG+ A RL V A+ + P L ++D +
Sbjct: 109 RLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQE 168
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRL 148
+ T + K+TWYRN +RL
Sbjct: 169 IATCN----SRNGNPAPKITWYRNGQRL 192
>BC050450-1|AAH50450.1| 628|Homo sapiens basal cell adhesion
molecule (Lutheran blood group) protein.
Length = 628
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTP 234
G + C E+ + + AY P + E + L L + + C V G+PTP
Sbjct: 333 GTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTP 392
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEA 270
LRW KDS + G + +L++ D S GTY CEA
Sbjct: 393 ALRWTKDSTPLGDGPMLSLSSITFD--SNGTYVCEA 426
Score = 31.5 bits (68), Expect = 4.6
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 63 RLTVSTARTGDTGVYT-LQASNAAGSDTARVRLEVSAEESPSGEDPPT-FLRRLQDLTVK 120
RL ++ A+ GD Y + + AAG+ A RL V A+ + P L ++D +
Sbjct: 109 RLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQE 168
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRL 148
+ T + K+TWYRN +RL
Sbjct: 169 IATCN----SRNGNPAPKITWYRNGQRL 192
>AY845133-1|AAV88096.1| 628|Homo sapiens Lutheran blood group
(Auberger b antigen included) protein.
Length = 628
Score = 48.8 bits (111), Expect = 3e-05
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRAL-LTEQGTVSLECKVVGVPTP 234
G + C E+ + + AY P + E + L L + + C V G+PTP
Sbjct: 333 GTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTP 392
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEA 270
LRW KDS + G + +L++ D S GTY CEA
Sbjct: 393 ALRWTKDSTPLGDGPMLSLSSITFD--SNGTYVCEA 426
Score = 31.5 bits (68), Expect = 4.6
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 63 RLTVSTARTGDTGVYT-LQASNAAGSDTARVRLEVSAEESPSGEDPPT-FLRRLQDLTVK 120
RL ++ A+ GD Y + + AAG+ A RL V A+ + P L ++D +
Sbjct: 109 RLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQE 168
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRL 148
+ T + K+TWYRN +RL
Sbjct: 169 IATCN----SRNGNPAPKITWYRNGQRL 192
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell
adhesion molecule 2 protein.
Length = 2113
Score = 48.8 bits (111), Expect = 3e-05
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 28/242 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+S RT D+G Y + +N GS A L V DP + L +G+
Sbjct: 339 LTISDLRTEDSGTYICEVTNTFGSAEATGILMVI--------DPLHVTLTPKKLKTGIGS 390
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S E + WYRN +L E +SI R S G + C A
Sbjct: 391 TVILSCALTGSPEFTIRWYRNTELVLPDEAISI-RGLSNETLLITSAQKSHSGAYQCFAT 449
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
R + +A ++ P V + G SL C G P P + W D
Sbjct: 450 ----RKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 505
Query: 243 REI-KAGDVFALTANAEDPTSL-------------GTYTCEAVNCMGRAYSSSKVHVVGR 288
I + G D T++ G Y C A N +G A ++++V G
Sbjct: 506 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 565
Query: 289 AS 290
S
Sbjct: 566 PS 567
Score = 47.2 bits (107), Expect = 9e-05
Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 8/155 (5%)
Query: 139 VTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNV 197
V+W ++ ++ R I G + R + G R S A L+V
Sbjct: 219 VSWEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSV 278
Query: 198 LVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD-----VF 251
P A P ++ + G TV L C G P P +RW KD R + A +
Sbjct: 279 TDP-AESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRIT 337
Query: 252 ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
LT + GTY CE N G A ++ + V+
Sbjct: 338 GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 372
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/200 (21%), Positives = 80/200 (40%), Gaps = 19/200 (9%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D +S L +++A+ +G Y A+ A TA+ ++ E+ P
Sbjct: 416 LPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKA--QTAQDFAIIALEDGT-----P 468
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE--AERVS--IVRDGSFFC 164
+ + V G + + + VTW ++ ++ + R + + DG+
Sbjct: 469 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 528
Query: 165 XXXXXXXXXXXGR-WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS 223
G + CTA N+ G A A +NV + P + +R + G +
Sbjct: 529 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV------RGPPSIRAMRNITAVAGRDT 582
Query: 224 L-ECKVVGVPTPVLRWFKDS 242
L C+V+G P ++W+KD+
Sbjct: 583 LINCRVIGYPYYSIKWYKDA 602
Score = 32.3 bits (70), Expect = 2.7
Identities = 25/102 (24%), Positives = 36/102 (35%), Gaps = 6/102 (5%)
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
++TW ++ + ++ V+I G +TC A N S L V
Sbjct: 687 RITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIV 746
Query: 198 LVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRW 238
VP P FV + G L C V G P P + W
Sbjct: 747 RVP-----PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMW 783
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule DSCAML1 protein.
Length = 2053
Score = 48.8 bits (111), Expect = 3e-05
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 28/242 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+S RT D+G Y + +N GS A L V DP + L +G+
Sbjct: 279 LTISDLRTEDSGTYICEVTNTFGSAEATGILMVI--------DPLHVTLTPKKLKTGIGS 330
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S E + WYRN +L E +SI R S G + C A
Sbjct: 331 TVILSCALTGSPEFTIRWYRNTELVLPDEAISI-RGLSNETLLITSAQKSHSGAYQCFAT 389
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
R + +A ++ P V + G SL C G P P + W D
Sbjct: 390 ----RKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 445
Query: 243 REI-KAGDVFALTANAEDPTSL-------------GTYTCEAVNCMGRAYSSSKVHVVGR 288
I + G D T++ G Y C A N +G A ++++V G
Sbjct: 446 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 505
Query: 289 AS 290
S
Sbjct: 506 PS 507
Score = 47.2 bits (107), Expect = 9e-05
Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 8/155 (5%)
Query: 139 VTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNV 197
V+W ++ ++ R I G + R + G R S A L+V
Sbjct: 159 VSWEKDTVSIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSV 218
Query: 198 LVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD-----VF 251
P A P ++ + G TV L C G P P +RW KD R + A +
Sbjct: 219 TDP-AESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRIT 277
Query: 252 ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
LT + GTY CE N G A ++ + V+
Sbjct: 278 GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 312
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/200 (21%), Positives = 80/200 (40%), Gaps = 19/200 (9%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D +S L +++A+ +G Y A+ A TA+ ++ E+ P
Sbjct: 356 LPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKA--QTAQDFAIIALEDGT-----P 408
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE--AERVS--IVRDGSFFC 164
+ + V G + + + VTW ++ ++ + R + + DG+
Sbjct: 409 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 468
Query: 165 XXXXXXXXXXXGR-WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS 223
G + CTA N+ G A A +NV + P + +R + G +
Sbjct: 469 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV------RGPPSIRAMRNITAVAGRDT 522
Query: 224 L-ECKVVGVPTPVLRWFKDS 242
L C+V+G P ++W+KD+
Sbjct: 523 LINCRVIGYPYYSIKWYKDA 542
Score = 32.3 bits (70), Expect = 2.7
Identities = 25/102 (24%), Positives = 36/102 (35%), Gaps = 6/102 (5%)
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
++TW ++ + ++ V+I G +TC A N S L V
Sbjct: 627 RITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIV 686
Query: 198 LVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRW 238
VP P FV + G L C V G P P + W
Sbjct: 687 RVP-----PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMW 723
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1b protein.
Length = 1842
Score = 48.8 bits (111), Expect = 3e-05
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 28/242 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+S RT D+G Y + +N GS A L V DP + L +G+
Sbjct: 68 LTISDLRTEDSGTYICEVTNTFGSAEATGILMVI--------DPLHVTLTPKKLKTGIGS 119
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S E + WYRN +L E +SI R S G + C A
Sbjct: 120 TVILSCALTGSPEFTIRWYRNTELVLPDEAISI-RGLSNETLLITSAQKSHSGAYQCFAT 178
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
R + +A ++ P V + G SL C G P P + W D
Sbjct: 179 ----RKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 234
Query: 243 REI-KAGDVFALTANAEDPTSL-------------GTYTCEAVNCMGRAYSSSKVHVVGR 288
I + G D T++ G Y C A N +G A ++++V G
Sbjct: 235 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 294
Query: 289 AS 290
S
Sbjct: 295 PS 296
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 7/87 (8%)
Query: 205 RPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGD-----VFALTANAED 259
RPE V +L ++ L C G P P +RW KD R + A + LT +
Sbjct: 17 RPEDVGT--SLYFVNDSLQLPCTAPGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLR 74
Query: 260 PTSLGTYTCEAVNCMGRAYSSSKVHVV 286
GTY CE N G A ++ + V+
Sbjct: 75 TEDSGTYICEVTNTFGSAEATGILMVI 101
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/200 (21%), Positives = 80/200 (40%), Gaps = 19/200 (9%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D +S L +++A+ +G Y A+ A TA+ ++ E+ P
Sbjct: 145 LPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKA--QTAQDFAIIALEDGT-----P 197
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE--AERVS--IVRDGSFFC 164
+ + V G + + + VTW ++ ++ + R + + DG+
Sbjct: 198 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 257
Query: 165 XXXXXXXXXXXGR-WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS 223
G + CTA N+ G A A +NV + P + +R + G +
Sbjct: 258 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV------RGPPSIRAMRNITAVAGRDT 311
Query: 224 L-ECKVVGVPTPVLRWFKDS 242
L C+V+G P ++W+KD+
Sbjct: 312 LINCRVIGYPYYSIKWYKDA 331
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1a protein.
Length = 2053
Score = 48.8 bits (111), Expect = 3e-05
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 28/242 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+S RT D+G Y + +N GS A L V DP + L +G+
Sbjct: 279 LTISDLRTEDSGTYICEVTNTFGSAEATGILMVI--------DPLHVTLTPKKLKTGIGS 330
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S E + WYRN +L E +SI R S G + C A
Sbjct: 331 TVILSCALTGSPEFTIRWYRNTELVLPDEAISI-RGLSNETLLITSAQKSHSGAYQCFAT 389
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
R + +A ++ P V + G SL C G P P + W D
Sbjct: 390 ----RKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 445
Query: 243 REI-KAGDVFALTANAEDPTSL-------------GTYTCEAVNCMGRAYSSSKVHVVGR 288
I + G D T++ G Y C A N +G A ++++V G
Sbjct: 446 EPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 505
Query: 289 AS 290
S
Sbjct: 506 PS 507
Score = 47.2 bits (107), Expect = 9e-05
Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 8/155 (5%)
Query: 139 VTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNV 197
V+W ++ ++ R I G + R + G R S A L+V
Sbjct: 159 VSWEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSV 218
Query: 198 LVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD-----VF 251
P A P ++ + G TV L C G P P +RW KD R + A +
Sbjct: 219 TDP-AESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRIT 277
Query: 252 ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
LT + GTY CE N G A ++ + V+
Sbjct: 278 GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 312
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/200 (21%), Positives = 80/200 (40%), Gaps = 19/200 (9%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D +S L +++A+ +G Y A+ A TA+ ++ E+ P
Sbjct: 356 LPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKA--QTAQDFAIIALEDGT-----P 408
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE--AERVS--IVRDGSFFC 164
+ + V G + + + VTW ++ ++ + R + + DG+
Sbjct: 409 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 468
Query: 165 XXXXXXXXXXXGR-WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS 223
G + CTA N+ G A A +NV + P + +R + G +
Sbjct: 469 YMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV------RGPPSIRAMRNITAVAGRDT 522
Query: 224 L-ECKVVGVPTPVLRWFKDS 242
L C+V+G P ++W+KD+
Sbjct: 523 LINCRVIGYPYYSIKWYKDA 542
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 48.8 bits (111), Expect = 3e-05
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 28/242 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+S RT D+G Y + +N GS A L V DP + L +G+
Sbjct: 318 LTISDLRTEDSGTYICEVTNTFGSAEATGILMVI--------DPLHVTLTPKKLKTGIGS 369
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
+ S E + WYRN +L E +SI R S G + C A
Sbjct: 370 TVILSCALTGSPEFTIRWYRNTELVLPDEAISI-RGLSNETLLITSAQKSHSGAYQCFAT 428
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDS 242
R + +A ++ P V + G SL C G P P + W D
Sbjct: 429 ----RKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 484
Query: 243 REI-KAGDVFALTANAEDPTSL-------------GTYTCEAVNCMGRAYSSSKVHVVGR 288
I + G D T++ G Y C A N +G A ++++V G
Sbjct: 485 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 544
Query: 289 AS 290
S
Sbjct: 545 PS 546
Score = 47.2 bits (107), Expect = 9e-05
Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 8/155 (5%)
Query: 139 VTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGG-RASCSAHLNV 197
V+W ++ ++ R I G + R + G R S A L+V
Sbjct: 198 VSWEKDTVSIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSV 257
Query: 198 LVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGD-----VF 251
P A P ++ + G TV L C G P P +RW KD R + A +
Sbjct: 258 TDP-AESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRIT 316
Query: 252 ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
LT + GTY CE N G A ++ + V+
Sbjct: 317 GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 351
Score = 39.5 bits (88), Expect = 0.018
Identities = 42/200 (21%), Positives = 80/200 (40%), Gaps = 19/200 (9%)
Query: 49 LDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPP 108
L D +S L +++A+ +G Y A+ A TA+ ++ E+ P
Sbjct: 395 LPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKA--QTAQDFAIIALEDGT-----P 447
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLE--AERVS--IVRDGSFFC 164
+ + V G + + + VTW ++ ++ + R + + DG+
Sbjct: 448 RIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTIS 507
Query: 165 XXXXXXXXXXXGR-WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS 223
G + CTA N+ G A A +NV + P + +R + G +
Sbjct: 508 HMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV------RGPPSIRAMRNITAVAGRDT 561
Query: 224 L-ECKVVGVPTPVLRWFKDS 242
L C+V+G P ++W+KD+
Sbjct: 562 LINCRVIGYPYYSIKWYKDA 581
Score = 32.3 bits (70), Expect = 2.7
Identities = 25/102 (24%), Positives = 36/102 (35%), Gaps = 6/102 (5%)
Query: 138 KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV 197
++TW ++ + ++ V+I G +TC A N S L V
Sbjct: 666 RITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIV 725
Query: 198 LVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRW 238
VP P FV + G L C V G P P + W
Sbjct: 726 RVP-----PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMW 762
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 48.4 bits (110), Expect = 4e-05
Identities = 73/299 (24%), Positives = 99/299 (33%), Gaps = 26/299 (8%)
Query: 60 GGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
GG+ L + D Y +A ++AG AR L V P + P R Q V
Sbjct: 1917 GGI-LRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSP---ERTQ---V 1969
Query: 120 KVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G R +TW R E L + S D G +
Sbjct: 1970 HAGRTVRLYCRAAGVPSATITW-RKEGGSLPPQARSERTD--IATLLIPAITTADAGFYL 2026
Query: 180 CTAENVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C A + G A + VL A + P +E +TE T+ L C V G + W
Sbjct: 2027 CVATSPAGTAQARIQVVVLSASDASQPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTW 2086
Query: 239 FKDSREIKAGDVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
++ + L P G Y C N G +S V V L
Sbjct: 2087 YRRGGSLPHHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSV---------L 2137
Query: 296 KPNSSGLSPEPPPIFTR--ELEDQYVRICEPFTLSCQIVVPPWPRS-VVWYNKEGKVEA 351
SG S P P TR +E + E TL VVP + V W+ + G + A
Sbjct: 2138 HGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA 2196
Score = 43.6 bits (98), Expect = 0.001
Identities = 56/246 (22%), Positives = 85/246 (34%), Gaps = 20/246 (8%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + + D GVY N S+T+R L V+ E+PS T + + +V+
Sbjct: 1730 GSELHFPSVQPSDAGVYICTCRNLHRSNTSRAELLVT--EAPSKPITVT-VEEQRSQSVR 1786
Query: 121 VGTRTRFLVEIIS-STECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G F+ S S + W R L + +G G +
Sbjct: 1787 PGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDF--NG---ILTIRNVQLSDAGTYV 1841
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRW 238
CT N+ +A L+V P L + G ++ C G PTP L W
Sbjct: 1842 CTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1901
Query: 239 -------FKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
+I G L A +PT Y C A + G+ + + +HV G
Sbjct: 1902 TGGPGGQLPAKAQIHGG---ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGP 1958
Query: 292 EGSLKP 297
+ P
Sbjct: 1959 RVQVSP 1964
Score = 41.9 bits (94), Expect = 0.003
Identities = 72/310 (23%), Positives = 105/310 (33%), Gaps = 29/310 (9%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDP---PTFL 111
S + G RL + D+G Y SN AGS L V+ + S S P P
Sbjct: 2578 SRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGS--RETSLIVTIQGSGSSHVPRVSPPIR 2635
Query: 112 RRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXX 171
TV G + + +TWY+ L + GS
Sbjct: 2636 IESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQT----HGSHL--RLHQMS 2689
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVL----VPKA--YKRPEFVEELRALLTEQGTVSLE 225
G + C A N S ++V P A P +E + + E T+ L
Sbjct: 2690 VADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLN 2749
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDV---FALTANAEDPTSLGTYTCEAVNCMGRAYSSSK 282
C V G + W K + + L + P G Y C + G +S
Sbjct: 2750 CVVPGQAHAQVTWHKRGGSLPSYHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEAS-- 2807
Query: 283 VHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRS-VV 341
V V AS ++ + G PPI +E R+ E TL + VVP + V
Sbjct: 2808 VLVTIEASGSSAVHVPAPG---GAPPI---RIEPSSSRVAEGQTLDLKCVVPGQAHAQVT 2861
Query: 342 WYNKEGKVEA 351
W+ + G + A
Sbjct: 2862 WHKRGGNLPA 2871
Score = 41.5 bits (93), Expect = 0.004
Identities = 60/250 (24%), Positives = 88/250 (35%), Gaps = 29/250 (11%)
Query: 43 SRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVS----- 97
SR G+SL R + E L A D+G Y + +N GS A +L V
Sbjct: 3335 SRVGSSLPGRATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGS 3390
Query: 98 --AEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVS 155
A P+G P T Q T +G F + S ++ W++ +L V
Sbjct: 3391 LPATSIPAGSTP-TVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSV- 3448
Query: 156 IVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA- 214
+DG G + C A G+A SA L + P + +R
Sbjct: 3449 --QDGVL---RIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQA-----LPSVLINIRTS 3498
Query: 215 --LLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPTSLGTYTCE 269
+ V EC +G P P + W K ++ G V + + + G Y C
Sbjct: 3499 VQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCT 3558
Query: 270 AVNCMGRAYS 279
A N G S
Sbjct: 3559 ATNAAGTTQS 3568
Score = 41.5 bits (93), Expect = 0.004
Identities = 53/218 (24%), Positives = 79/218 (36%), Gaps = 22/218 (10%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR-RLQDLTVKVGTRTRFLVEIIS 133
G Y QA G A +L + A P + R TV VG F +
Sbjct: 3464 GTYICQAHGPWGKAQASAQLVIQAL-------PSVLINIRTSVQTVVVGHAVEFECLALG 3516
Query: 134 STECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSA 193
+ +VTW + L R IV+ G G++ CTA N G + +
Sbjct: 3517 DPKPQVTWSKVGGHL----RPGIVQSGGVV--RIAHVELADAGQYRCTATNAAG--TTQS 3568
Query: 194 HLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA- 252
H+ +LV +A + +E+R + C G PTP + W K +
Sbjct: 3569 HVLLLV-QALPQISMPQEVR--VPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLEN 3625
Query: 253 --LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
L + P GTY C A N G+ + + + V R
Sbjct: 3626 NMLMLPSVQPQDAGTYVCTATNRQGKVKAFAHLQVPER 3663
Score = 41.1 bits (92), Expect = 0.006
Identities = 57/234 (24%), Positives = 83/234 (35%), Gaps = 20/234 (8%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G +T+ R + G Y ASNA G + V L V PPT + L + V
Sbjct: 3075 GSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSV--------HGPPT-VSVLPEGPVW 3125
Query: 121 VGTRTRFLVEIISSTE--CKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V +E +S+ E W R + E+ + S G +
Sbjct: 3126 VKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHTVLQISSAKPSDAGTY 3185
Query: 179 TCTAENVGGRASCSAHLNV-LVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVL 236
C A+N G A + V A P+ E L E G T +L C G P +
Sbjct: 3186 VCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPARTI 3245
Query: 237 RWFKDSREIK-----AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W K + GD + A+ + G Y C A + G A ++ +HV
Sbjct: 3246 HWSKLRSPLPWQHRLEGDTLIIPRVAQQDS--GQYICNATSPAGHAEATIILHV 3297
Score = 39.9 bits (89), Expect = 0.013
Identities = 55/243 (22%), Positives = 84/243 (34%), Gaps = 24/243 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+ + D G Y SN D L V A + S P LTV+ G
Sbjct: 1827 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSA---PVVSIHPPQLTVQPGQ 1883
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F S + W L A+ + + G ++ C A
Sbjct: 1884 LAEFRCSATGSPTPTLEWTGGPGGQLPAK--AQIHGGIL---RLPAVEPTDQAQYLCRAH 1938
Query: 184 NVGGRASCSAHLNVLV---PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
+ G+ A L+V P+ PE R + TV L C+ GVP+ + W K
Sbjct: 1939 SSAGQQVARAVLHVHGGGGPRVQVSPE-----RTQVHAGRTVRLYCRAAGVPSATITWRK 1993
Query: 241 DSREI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGS 294
+ + + D+ L A G Y C A + G A +++ VV ++ + S
Sbjct: 1994 EGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA--QARIQVVVLSASDAS 2051
Query: 295 LKP 297
P
Sbjct: 2052 QPP 2054
Score = 39.9 bits (89), Expect = 0.013
Identities = 70/313 (22%), Positives = 106/313 (33%), Gaps = 33/313 (10%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE-SPSGEDPPTFLR- 112
S + G L + D+G Y +A+N + A + + VS SPS +R
Sbjct: 2674 SRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRI 2733
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL----------LEAERVSIVRDGSF 162
V G + +VTW++ L L VS G +
Sbjct: 2734 ESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSYHQTRGSRLRLHHVSPADSGEY 2793
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV 222
C T E AS S+ ++V P P +E + + E T+
Sbjct: 2794 VCRVMGSSGPLEASVLV-TIE-----ASGSSAVHVPAPGGAP-PIRIEPSSSRVAEGQTL 2846
Query: 223 SLECKVVGVPTPVLRWFKDSREIKAGDVF---ALTANAEDPTSLGTYTCEAVNCMGRAYS 279
L+C V G + W K + A L N P G Y+C+ G +
Sbjct: 2847 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2906
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRS 339
S V +++P+S G P P +E + E TL VVP +
Sbjct: 2907 SVLV----------TIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHA 2956
Query: 340 -VVWYNKEGKVEA 351
V WY + G + A
Sbjct: 2957 QVTWYKRGGSLPA 2969
Score = 35.5 bits (78), Expect = 0.28
Identities = 65/299 (21%), Positives = 102/299 (34%), Gaps = 31/299 (10%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEV--SAEESPSGEDPPTFLR--RLQD 116
G RL + D+G Y + N +G A + + V PS P R R++
Sbjct: 2101 GSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEP 2160
Query: 117 LTVKV--GTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXX 174
+ V G + +VTW++ L + GS
Sbjct: 2161 SSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTH----GSLL--RLHQVTPAD 2214
Query: 175 XGRWTCTAENVGGRASCSAHLNV---LVPKAYKRPEFVEELRALLTEQGTVSLECKVVGV 231
G + C G S + + ++P P +E + + E T+ L C V G
Sbjct: 2215 SGEYVCHVVGTSGPLEASVLVTIEASVIPGPIP-PVRIESSSSTVAEGQTLDLSCVVAGQ 2273
Query: 232 PTPVLRWFKDSREIKAGDVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
+ W+K + A L P G Y C A N M +S V V G
Sbjct: 2274 AHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGM---EASITVTVTG- 2329
Query: 289 ASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
+G+ +G S +P +E ++ E TL VVP + V ++K G
Sbjct: 2330 --TQGANLAYPAG-STQP-----IRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG 2380
Score = 35.1 bits (77), Expect = 0.38
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 15/122 (12%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVG----- 230
GR+ C N G A A L V P P + T Q T LE K +G
Sbjct: 3363 GRYRCRVTNKVGSAEAFAQLLVQGPPG-SLPATSIPAGSTPTVQVTPQLETKSIGASVEF 3421
Query: 231 ---VPTP---VLRWFKDSREIKAGDVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSS 281
VP+ LRWFK+ ++ G L D + GTY C+A G+A +S+
Sbjct: 3422 HCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASA 3481
Query: 282 KV 283
++
Sbjct: 3482 QL 3483
Score = 34.7 bits (76), Expect = 0.50
Identities = 37/148 (25%), Positives = 53/148 (35%), Gaps = 16/148 (10%)
Query: 206 PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPTS 262
P +E A L T+ L C V + W+K + + L P
Sbjct: 2537 PVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPAD 2596
Query: 263 LGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRIC 322
G Y C N G +S V + G S S P S PPI +E +
Sbjct: 2597 SGEYVCHVSNGAGSRETSLIVTIQGSGS---SHVPRVS------PPI---RIESSSPTVV 2644
Query: 323 EPFTLSCQIVVPPWPRSVV-WYNKEGKV 349
E TL VV P++++ WY + G +
Sbjct: 2645 EGQTLDLNCVVARQPQAIITWYKRGGSL 2672
Score = 34.7 bits (76), Expect = 0.50
Identities = 54/277 (19%), Positives = 90/277 (32%), Gaps = 22/277 (7%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----PSGEDPPT 109
S + G RL + D+G Y + ++G A V + + A S P+ P
Sbjct: 2771 SYHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPP 2830
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXX 169
V G + +VTW++ L +V G
Sbjct: 2831 IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVH----GPLL--RLNQ 2884
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNV-------LVPKAYKRPEFVEELRALLTEQGTV 222
G ++C G S + + + +P ++E + +TE T+
Sbjct: 2885 VSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTL 2944
Query: 223 SLECKVVGVPTPVLRWFKDSREIKAGDV---FALTANAEDPTSLGTYTCEAVNCMGRAYS 279
L C V G + W+K + A L + P G Y C A G
Sbjct: 2945 DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHHVSPADSGEYVCRAAGGPGPEQE 3004
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELED 316
+S V S S + S +S +PP ++ +D
Sbjct: 3005 AS-FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 3040
>U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4
protein.
Length = 1070
Score = 48.4 bits (110), Expect = 4e-05
Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A L VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQAVLQVLEKLKFTPPPQPQQCMGFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 41.1 bits (92), Expect = 0.006
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 623 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 682
Query: 287 GRASREGSLKPNS 299
+ E S P S
Sbjct: 683 DKPVPEESEGPGS 695
Score = 34.7 bits (76), Expect = 0.50
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVKLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + +A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFSQACSS 212
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 48.4 bits (110), Expect = 4e-05
Identities = 60/230 (26%), Positives = 78/230 (33%), Gaps = 24/230 (10%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D G Y A N G A L V A PP F+ R +D V G F E
Sbjct: 4 DEGTYMCIAENRVGKMEASATLTVRARPVA----PPQFVVRPRDQIVAQGRTVTFPCETK 59
Query: 133 SSTECKVTWYRN-ERRLL-------EAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAEN 184
+ + V W + + LL R S+ G G + C A
Sbjct: 60 GNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL---TITNIQRSDAGYYICQALT 116
Query: 185 VGGRASCSAHLNVLVPKAYKRPEFVEELRA--LLTEQGTVSLECKVVGVPTPVLRWFKDS 242
V G A L V + P + + A L GT L+CK G P PV+ W K+
Sbjct: 117 VAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEG 176
Query: 243 REIKAGDVFA-------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
D A L + GTYTC A + G S+ + V
Sbjct: 177 FTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 226
Score = 45.2 bits (102), Expect = 4e-04
Identities = 44/174 (25%), Positives = 68/174 (39%), Gaps = 5/174 (2%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTP 234
G + C AEN G+ SA L V + P+FV R + QG TV+ C+ G P P
Sbjct: 6 GTYMCIAENRVGKMEASATLTVRA-RPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQP 64
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTS-LGTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
+ W K+ + N+ S G T + Y + V +
Sbjct: 65 AVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK 124
Query: 294 SLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
+ + L+ PPPI + +Q + + L C+ P P V+ + KEG
Sbjct: 125 AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLP--VISWLKEG 176
Score = 37.1 bits (82), Expect = 0.093
Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 6/135 (4%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT++ + D G Y QA AGS A+ +LEV+ + + PP L+ + T+ V
Sbjct: 97 LTITNIQRSDAGYYICQALTVAGSILAKAQLEVT--DVLTDRPPPIILQGPANQTLAVDG 154
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAE-RVSIVRDGSFFCXXXXXXXXXXXGRWTCTA 182
+ ++W + + R +I G+ G +TC A
Sbjct: 155 TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTL---QIKNLRISDTGTYTCVA 211
Query: 183 ENVGGRASCSAHLNV 197
+ G S SA L+V
Sbjct: 212 TSSSGETSWSAVLDV 226
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 41.1 bits (92), Expect = 0.006
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 623 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 682
Query: 287 GRASREGSLKPNS 299
+ E S P S
Sbjct: 683 DKPVPEESEGPGS 695
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 48.0 bits (109), Expect = 5e-05
Identities = 79/326 (24%), Positives = 112/326 (34%), Gaps = 41/326 (12%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T + G SL + +E L + T D G Y A++ AG+ AR+++ V
Sbjct: 1988 TWRKEGGSLPPQ-ARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARMQVVVL--- 2043
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
S S PP +V G + S +VTWYR L +V R
Sbjct: 2044 SASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR-- 2101
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVL-----------VPKAYKRPEFV 209
G + C EN G S ++VL VP + RP +
Sbjct: 2102 ----LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGS-TRPIRI 2156
Query: 210 EELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV---FALTANAEDPTSLGTY 266
E + + E T+ L C V G + W K + A L + P G Y
Sbjct: 2157 EPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEY 2216
Query: 267 TCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFT 326
C V G +S V + E S+ P P PP +E + E T
Sbjct: 2217 VCHVVGTSGPLEASVLVTI------EASVIP-----GPIPPV----RIESSSSTVAEGQT 2261
Query: 327 LSCQIVVPPWPRS-VVWYNKEGKVEA 351
L VV + V WY + G + A
Sbjct: 2262 LDLSCVVAGQAHAQVTWYKRGGSLPA 2287
Score = 44.8 bits (101), Expect = 5e-04
Identities = 58/234 (24%), Positives = 86/234 (36%), Gaps = 20/234 (8%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G +T+ R + G Y ASNA G + V L V PPT + L + V
Sbjct: 3073 GSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG--------PPT-VSVLPEGPVW 3123
Query: 121 VGTRTRFLVEIISSTECKVT--WYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW 178
V +E +S+ E + + W R + E+ + S G +
Sbjct: 3124 VKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTY 3183
Query: 179 TCTAENVGGRASCSAHLNVLV-PKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVL 236
C A+N G A + V A P+ E L E G T +L C G P P +
Sbjct: 3184 VCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTI 3243
Query: 237 RWFKDSREIK-----AGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
W K + GD + A+ + G Y C A + G A ++ +HV
Sbjct: 3244 HWSKLRSPLPWQHRLEGDTLIIPRVAQQDS--GQYICNATSPAGHAEATIILHV 3295
Score = 43.6 bits (98), Expect = 0.001
Identities = 55/246 (22%), Positives = 85/246 (34%), Gaps = 20/246 (8%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + + D GVY N S+T+R L V+ E+PS T + + +V+
Sbjct: 1728 GSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVT--EAPSKPITVT-VEEQRSQSVR 1784
Query: 121 VGTRTRFLVEIISSTEC-KVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
G F+ S + + W R L + +G G +
Sbjct: 1785 PGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDF--NGIL---TIRNVQLSDAGTYV 1839
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRW 238
CT N+ +A L+V P L + G ++ C G PTP L W
Sbjct: 1840 CTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899
Query: 239 -------FKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASR 291
+I G L A +PT Y C A + G+ + + +HV G
Sbjct: 1900 TGGPGGQLPAKAQIHGG---ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGP 1956
Query: 292 EGSLKP 297
+ P
Sbjct: 1957 RVQVSP 1962
Score = 43.2 bits (97), Expect = 0.001
Identities = 71/309 (22%), Positives = 107/309 (34%), Gaps = 27/309 (8%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGS-DTAR-VRLEVSAEESPSGEDPPTFLR 112
S + G RL + D+G Y SN AGS +T+ V ++ S PP +
Sbjct: 2576 SRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIE 2635
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXX 172
TV G + + +TWY+ L + GS
Sbjct: 2636 S-SSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQT----HGSHL--RLHQMSV 2688
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVL----VPKA--YKRPEFVEELRALLTEQGTVSLEC 226
G + C A N S ++V P A P +E + + E T+ L C
Sbjct: 2689 ADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC 2748
Query: 227 KVVGVPTPVLRWFKDSREIKAGDV---FALTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
V G + W K + + L + P G Y C + G +S V
Sbjct: 2749 VVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEAS--V 2806
Query: 284 HVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRS-VVW 342
V AS ++ + G PPI +E R+ E TL + VVP + V W
Sbjct: 2807 LVTIEASGSSAVHVPAPG---GAPPI---RIEPSSSRVAEGQTLDLKCVVPGQAHAQVTW 2860
Query: 343 YNKEGKVEA 351
+ + G + A
Sbjct: 2861 HKRGGNLPA 2869
Score = 41.5 bits (93), Expect = 0.004
Identities = 60/250 (24%), Positives = 88/250 (35%), Gaps = 29/250 (11%)
Query: 43 SRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVS----- 97
SR G+SL R + E L A D+G Y + +N GS A +L V
Sbjct: 3333 SRVGSSLPGRATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGS 3388
Query: 98 --AEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVS 155
A P+G P T Q T +G F + S ++ W++ +L V
Sbjct: 3389 LPATSIPAGSTP-TVQVTPQLETKSIGASVEFHCAVPSDQGTQLRWFKEGGQLPPGHSV- 3446
Query: 156 IVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRA- 214
+DG G + C A G+A SA L + P + +R
Sbjct: 3447 --QDGVL---RIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQA-----LPSVLINIRTS 3496
Query: 215 --LLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPTSLGTYTCE 269
+ V EC +G P P + W K ++ G V + + + G Y C
Sbjct: 3497 VQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCT 3556
Query: 270 AVNCMGRAYS 279
A N G S
Sbjct: 3557 ATNAAGTTQS 3566
Score = 40.7 bits (91), Expect = 0.008
Identities = 53/218 (24%), Positives = 79/218 (36%), Gaps = 22/218 (10%)
Query: 75 GVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLR-RLQDLTVKVGTRTRFLVEIIS 133
G Y QA G A +L + A P + R TV VG F +
Sbjct: 3462 GTYICQAHGPWGKAQASAQLVIQAL-------PSVLINIRTSVQTVVVGHAVEFECLALG 3514
Query: 134 STECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSA 193
+ +VTW + L R IV+ G G++ CTA N G + +
Sbjct: 3515 DPKPQVTWSKVGGHL----RPGIVQSGGVV--RIAHVELADAGQYRCTATNAAG--TTQS 3566
Query: 194 HLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA- 252
H+ +LV +A + +E+R + C G PTP + W K +
Sbjct: 3567 HVLLLV-QALPQISMPQEVR--VPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLEN 3623
Query: 253 --LTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGR 288
L + P GTY C A N G+ + + + V R
Sbjct: 3624 NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661
Score = 39.9 bits (89), Expect = 0.013
Identities = 70/313 (22%), Positives = 106/313 (33%), Gaps = 33/313 (10%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE-SPSGEDPPTFLR- 112
S + G L + D+G Y +A+N + A + + VS SPS +R
Sbjct: 2672 SRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRI 2731
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL----------LEAERVSIVRDGSF 162
V G + +VTW++ L L VS G +
Sbjct: 2732 ESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEY 2791
Query: 163 FCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTV 222
C T E AS S+ ++V P P +E + + E T+
Sbjct: 2792 VCRVMGSSGPLEASVLV-TIE-----ASGSSAVHVPAPGGAP-PIRIEPSSSRVAEGQTL 2844
Query: 223 SLECKVVGVPTPVLRWFKDSREIKAGDVF---ALTANAEDPTSLGTYTCEAVNCMGRAYS 279
L+C V G + W K + A L N P G Y+C+ G +
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRS 339
S V +++P+S G P P +E + E TL VVP +
Sbjct: 2905 SVLV----------TIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHA 2954
Query: 340 -VVWYNKEGKVEA 351
V WY + G + A
Sbjct: 2955 QVTWYKRGGSLPA 2967
Score = 39.1 bits (87), Expect = 0.023
Identities = 53/232 (22%), Positives = 79/232 (34%), Gaps = 22/232 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
LT+ + D G Y SN D L V A + S P LTV+ G
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSA---PVVSIHPPQLTVQPGQ 1881
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
F S + W L A+ + + G ++ C A
Sbjct: 1882 LAEFRCSATGSPTPTLEWTGGPGGQLPAK--AQIHGGIL---RLPAVEPTDQAQYLCRAH 1936
Query: 184 NVGGRASCSAHLNVLV---PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFK 240
+ G+ A L+V P+ PE R + TV L C+ GVP+ + W K
Sbjct: 1937 SSAGQQVARAVLHVHGGGGPRVQVSPE-----RTQVHAGRTVRLYCRAAGVPSATITWRK 1991
Query: 241 DSREI------KAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
+ + + D+ L A G Y C A + G A + +V V+
Sbjct: 1992 EGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARMQVVVL 2043
Score = 36.7 bits (81), Expect = 0.12
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 9/67 (13%)
Query: 221 TVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSL---------GTYTCEAV 271
TV+ C +GVPTP++ W + I + +T+ T + G YTCEA+
Sbjct: 423 TVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAM 482
Query: 272 NCMGRAY 278
N G +
Sbjct: 483 NARGMVF 489
Score = 35.9 bits (79), Expect = 0.22
Identities = 48/206 (23%), Positives = 71/206 (34%), Gaps = 19/206 (9%)
Query: 41 TKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEE 100
T + G SL R + G L + D+G Y +G A V + + A
Sbjct: 2184 TWHKRGGSLPAR----HQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASV 2239
Query: 101 SPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDG 160
P G PP + TV G + +VTWY+ L +V R
Sbjct: 2240 IP-GPIPPVRIESSSS-TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLY 2297
Query: 161 SFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHL------NVLVPKAYKRPEFVEELRA 214
F G++ C A N G AS + + N+ P +P +E +
Sbjct: 2298 IF------QASPADAGQYVCRASN-GMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSS 2350
Query: 215 LLTEQGTVSLECKVVGVPTPVLRWFK 240
+ E T+ L C V G + W K
Sbjct: 2351 QVAEGQTLDLNCVVPGQSHAQVTWHK 2376
Score = 35.5 bits (78), Expect = 0.28
Identities = 54/277 (19%), Positives = 91/277 (32%), Gaps = 22/277 (7%)
Query: 55 STEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEES-----PSGEDPPT 109
S + G RL + D+G Y + ++G A V + + A S P+ P
Sbjct: 2769 SHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPP 2828
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXX 169
V G + +VTW++ L +V G
Sbjct: 2829 IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVH----GPLL--RLNQ 2882
Query: 170 XXXXXXGRWTCTAENVGGRASCSAHLNV-------LVPKAYKRPEFVEELRALLTEQGTV 222
G ++C G S + + + +P ++E + +TE T+
Sbjct: 2883 VSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTL 2942
Query: 223 SLECKVVGVPTPVLRWFKDSREIKAGDV---FALTANAEDPTSLGTYTCEAVNCMGRAYS 279
L C V G + W+K + A L + P G Y C A + G
Sbjct: 2943 DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQE 3002
Query: 280 SSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELED 316
+S V S S + S +S +PP ++ +D
Sbjct: 3003 AS-FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 3038
Score = 35.1 bits (77), Expect = 0.38
Identities = 37/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)
Query: 206 PEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFA---LTANAEDPTS 262
P +E A L T+ L C V + W+K + + L P
Sbjct: 2535 PVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPAD 2594
Query: 263 LGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRIC 322
G Y C N G +S V + G S S P+ S PPI +E +
Sbjct: 2595 SGEYVCHVSNGAGSRETSLIVTIQGSGS---SHVPSVS------PPI---RIESSSPTVV 2642
Query: 323 EPFTLSCQIVVPPWPRSVV-WYNKEGKV 349
E TL VV P++++ WY + G +
Sbjct: 2643 EGQTLDLNCVVARQPQAIITWYKRGGSL 2670
Score = 35.1 bits (77), Expect = 0.38
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 15/122 (12%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVG----- 230
GR+ C N G A A L V P P + T Q T LE K +G
Sbjct: 3361 GRYRCRVTNKVGSAEAFAQLLVQGPPG-SLPATSIPAGSTPTVQVTPQLETKSIGASVEF 3419
Query: 231 ---VPTPV---LRWFKDSREIKAGDVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSS 281
VP+ LRWFK+ ++ G L D + GTY C+A G+A +S+
Sbjct: 3420 HCAVPSDQGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASA 3479
Query: 282 KV 283
++
Sbjct: 3480 QL 3481
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 41.1 bits (92), Expect = 0.006
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 623 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 682
Query: 287 GRASREGSLKPNS 299
+ E S P S
Sbjct: 683 DKPVPEESEGPGS 695
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 48.0 bits (109), Expect = 5e-05
Identities = 48/199 (24%), Positives = 80/199 (40%), Gaps = 17/199 (8%)
Query: 96 VSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVS 155
+ A+ES S P T + Q++T + + + ++W R + + ++
Sbjct: 224 IPAKESKSFHTP-TIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTR 282
Query: 156 IVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGR--ASCSAHLNVLVPKAYKRPEFVEELR 213
++ +G+ G + C A G R A L VL P P FVE
Sbjct: 283 VLGNGNLMISDVRLQHA---GVYVCRATTPGTRNFTVAMATLTVLAP-----PSFVEWPE 334
Query: 214 ALLTEQ-GTVSLECKVVGVPTPVLRWFKDSREIKA-GDV----FALTANAEDPTSLGTYT 267
+L + GT C+ G+P+P + W K+ R+I + G + L N P Y
Sbjct: 335 SLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNSKLVINQIIPEDDAIYQ 394
Query: 268 CEAVNCMGRAYSSSKVHVV 286
C A N G S +++ VV
Sbjct: 395 CMAENSQGSILSRARLTVV 413
Score = 43.6 bits (98), Expect = 0.001
Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 7/133 (5%)
Query: 109 TFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCX--X 166
+F++ QD+TV + KVTW +N ++ E +R+ ++ +GS +
Sbjct: 40 SFVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEVE 99
Query: 167 XXXXXXXXXGRWTCTAEN-VGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G + C A N G S AHL + A++ V+ + + E G
Sbjct: 100 GRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFE----VQPISTEVHEGGVARFA 155
Query: 226 CKVVGVPTPVLRW 238
CK+ P V+ W
Sbjct: 156 CKISSHPPAVITW 168
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 48.0 bits (109), Expect = 5e-05
Identities = 61/255 (23%), Positives = 104/255 (40%), Gaps = 30/255 (11%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGS-DTARVRLEVSAEESPS-GEDPPT 109
R S + G LT+S + DTG Y +A+ + + AR + E P +P +
Sbjct: 335 RITSGLHSFGRHLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPES 394
Query: 110 FLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRL--LEAERVSIVRDGSFFCXXX 167
+ + TV +G + + + T + WY++ + L+ R ++ G
Sbjct: 395 RISAEVEETVDIGCQA---MGVPLPT---LQWYKDAISISRLQNPRYKVLASGGL---RI 445
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNV--LVPKAYKRPEFVEELRALLTEQGTVSLE 225
G + C A N GG +L+V + P +RP + +T+ T L
Sbjct: 446 QKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRP-----VDTTVTDGMTAILR 500
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDV----FALTANAE---DPTSL---GTYTCEAVNCMG 275
C+V G P P + W +++ + +G V F L + P + G YTC A N G
Sbjct: 501 CEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEG 560
Query: 276 RAYSSSKVHVVGRAS 290
+S+ + V R S
Sbjct: 561 SLNASATLTVWNRTS 575
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/192 (25%), Positives = 75/192 (39%), Gaps = 18/192 (9%)
Query: 63 RLTVSTARTGDTGVYTLQASNAAGSDTAR---VRLEVSAEESPSGEDPPTFLRRLQDLTV 119
+L + T D G Y +QA N + + L ++ + PT + + +V
Sbjct: 245 QLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSV 304
Query: 120 KVGTRTRFLVEIISST---ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
G+ L I S+ + VTW RN R+ S R G
Sbjct: 305 VAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLH-SFGRH-----LTISNPTSADTG 358
Query: 177 RWTCTAENVGGR---ASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPT 233
+ C A G A +A L ++ P Y E + A + E TV + C+ +GVP
Sbjct: 359 PYVCEAALPGSAFEPARATAFLFIIEPP-YFTAEPESRISAEVEE--TVDIGCQAMGVPL 415
Query: 234 PVLRWFKDSREI 245
P L+W+KD+ I
Sbjct: 416 PTLQWYKDAISI 427
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 41.1 bits (92), Expect = 0.006
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 623 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 682
Query: 287 GRASREGSLKPNS 299
+ E S P S
Sbjct: 683 DKPVPEESEGPGS 695
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
>AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor
precursor PTK7-5 protein.
Length = 816
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 41.1 bits (92), Expect = 0.006
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 623 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 682
Query: 287 GRASREGSLKPNS 299
+ E S P S
Sbjct: 683 DKPVPEESEGPGS 695
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
>AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor
precursor PTK7-4 protein.
Length = 1014
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
Score = 32.7 bits (71), Expect = 2.0
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRW 238
++W
Sbjct: 623 IQW 625
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 41.1 bits (92), Expect = 0.006
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 623 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 682
Query: 287 GRASREGSLKPNS 299
+ E S P S
Sbjct: 683 DKPVPEESEGPGS 695
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 373 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 424
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 425 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 479
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 480 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 536
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 537 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 574
Score = 41.1 bits (92), Expect = 0.006
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 566 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 622
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 623 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 682
Query: 287 GRASREGSLKPNS 299
+ E S P S
Sbjct: 683 DKPVPEESEGPGS 695
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 97 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 156
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 157 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 48.0 bits (109), Expect = 5e-05
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 12/97 (12%)
Query: 201 KAYKRPEFVEELRALLTEQGTVS-LECKVVGVPTPVLRWFKDSREIKAGDVFALTANAED 259
K + +P F + +R L +G+ + +CK+ G P P + WFKD + I+ F + + +
Sbjct: 450 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 509
Query: 260 PTSL----------GTYTCEAVNCMGRAYSSSKVHVV 286
SL YTC+AVN +G A +++ H+V
Sbjct: 510 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE-HIV 545
Score = 47.6 bits (108), Expect = 7e-05
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Query: 88 DTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERR 147
D ++ LE AEE P + P F + ++DL V G+ RF +I + +V W+++++
Sbjct: 437 DVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 494
Query: 148 LLEAERVSIVRDGSFFCXXXXXXX-XXXXGRWTCTAENVGGRASCSA 193
+ E+ I D C ++TC A N G A+C+A
Sbjct: 495 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 541
Score = 33.5 bits (73), Expect = 1.1
Identities = 21/59 (35%), Positives = 26/59 (44%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTV 119
G +LT+ AR G YTL N GS A+V L V + P P R LT+
Sbjct: 12 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 70
>AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine
kinase 7 isoform a precursor variant protein.
Length = 773
Score = 48.0 bits (109), Expect = 5e-05
Identities = 51/221 (23%), Positives = 86/221 (38%), Gaps = 28/221 (12%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L ++ D GVYT A+N AG V + V+ P++L++ QD ++
Sbjct: 413 GHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVAT--------VPSWLKKPQDSQLE 464
Query: 121 VGTRTRFLVEIISST-ECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRW- 178
G + +L + +T + V WYRN+ + E R + ++G+ G W
Sbjct: 465 EG-KPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTL----RINSVEVYDGTWY 519
Query: 179 TCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
C + G A + VL + P ++ E ++ C G P ++W
Sbjct: 520 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKE---ATVPCSATGREKPTIKW 576
Query: 239 FK-DSREI------KAGDVFALTANAEDPTSLGTYTCEAVN 272
+ D + AG + +D G YTC A N
Sbjct: 577 ERADGSSLPEWVTDNAGTLHFARVTRDD---AGNYTCIASN 614
Score = 40.3 bits (90), Expect = 0.010
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 18/149 (12%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
G +TC A N G + AH+ + V A VE R + + T L+C+ G P P+
Sbjct: 606 GNYTCIASN-GPQGQIRAHVQLTV--AVFITFKVEPERTTVYQGHTALLQCEAQGDPKPL 662
Query: 236 LRWFKDSREI---KAG---DVF---ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVV 286
++W R + K G +F +L + P G YTC A N ++ + ++VV
Sbjct: 663 IQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVV 722
Query: 287 GRASREGSLKPNSSG----LSPEPPPIFT 311
G G L SG LSP P+ T
Sbjct: 723 GMG--WGGLCCTGSGGPRRLSPCTQPLCT 749
Score = 37.5 bits (83), Expect = 0.071
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 176 GRWTCTA-ENVGGRASCSAHLNVLVPKAYKRPEFVEE--LRALLTEQGTVSLECKVVGVP 232
G + C A ++V G + SA+ + + P ++ A + Q V+L C + G P
Sbjct: 137 GTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP 196
Query: 233 TPVLRWFKDSREIKAGD----VFA----LTANAEDPTSLGTYTCEAVNCMGRAYSS 280
P +WF+D + G V + LT P G Y+C A + G+A SS
Sbjct: 197 RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 252
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 47.6 bits (108), Expect = 7e-05
Identities = 56/229 (24%), Positives = 80/229 (34%), Gaps = 19/229 (8%)
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
T + G F S E ++W+RN + + E E+ + GS G
Sbjct: 221 TAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKY--ILKGSNTELTVRNIINSDGGP 278
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G A L V V +P ++ E G V+L C G P P +
Sbjct: 279 YVCRATNKAGEDEKQAFLQVFV-----QPHIIQLKNETTYENGQVTLVCDAEGEPIPEIT 333
Query: 238 WFKDSREIKAGDVFALTANAEDPTS----LGTYTCEAVNCMGRAYSSSKVHVVGRASREG 293
W +A D F T + P G + +++ S S + ASR G
Sbjct: 334 W------KRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIG 387
Query: 294 SLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
S L E P F Y P +SC + P P S+ W
Sbjct: 388 G-HQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNP-PASIHW 434
Score = 44.8 bits (101), Expect = 5e-04
Identities = 57/244 (23%), Positives = 96/244 (39%), Gaps = 33/244 (13%)
Query: 51 DRFVSTE----EAGGVR--LTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPS 103
++ +ST+ + GGVR LT+ A D G+Y QA++A G + A V LE+ +
Sbjct: 59 EKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQK---- 114
Query: 104 GEDPPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTW-YRNER-RLLEAERVSIVRDGS 161
TF + K G + + SS V+W Y NE + R++++ + +
Sbjct: 115 ----LTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNN 170
Query: 162 FFCXXXXXXXXXXXGRWTCTAENVGGRASCSAH---LNVLVPKAYKRPEFVEELRALLTE 218
G + C V R + V VP A P+ + A
Sbjct: 171 L---QILNINKSDEGIYRCEG-RVEARGEIDFRDIIVIVNVPPAISMPQ--KSFNATAER 224
Query: 219 QGTVSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT-------SLGTYTCEAV 271
++ C+ G P P + WF++ + I+ + + L + + T G Y C A
Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRAT 284
Query: 272 NCMG 275
N G
Sbjct: 285 NKAG 288
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 47.2 bits (107), Expect = 9e-05
Identities = 53/200 (26%), Positives = 80/200 (40%), Gaps = 18/200 (9%)
Query: 107 PPTFLR-RLQDLTVKVGTRTRFLVEIISSTECKVTWYRN-ERRLLEAERVSIVRDGSFFC 164
PP L R Q + V + RTR S + W++N + L+ + +GS
Sbjct: 423 PPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL-- 480
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQGTVS 223
G +TC A N+ G+A L V P + Y+ PE R TV
Sbjct: 481 -EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGT-----TVQ 534
Query: 224 LECKVVGVPTPVL--RWFKDSREIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGR 276
LEC+V P+ L W KD + G+ +LT G+YTC A + +
Sbjct: 535 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 594
Query: 277 AYSSSKVHVVGRASREGSLK 296
+ + + V+GR R L+
Sbjct: 595 DLAKAYLTVLGRPDRPRDLE 614
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/230 (23%), Positives = 89/230 (38%), Gaps = 20/230 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ D+G Y ASN GS R + V + +P D P ++L + G
Sbjct: 295 LRITNVSEEDSGEYFCLASNKMGS--IRHTISVRVKAAPYWLDEP------KNLILAPGE 346
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R + + + V W N L A + R+ + + C
Sbjct: 347 DGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAGDTIIFRDTQISSRAVYQCNTS 405
Query: 184 NVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G +A ++VL VP P + +R +L + L+C G P P LRWFK+
Sbjct: 406 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 462
Query: 243 R--EIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+ + G+ +L G YTC A N +G+A + ++ V
Sbjct: 463 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 512
Score = 31.5 bits (68), Expect = 4.6
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVV-GVPT 233
G + C A N G A S + + V K+ P+ E L ++ ++G ++L+C G+P+
Sbjct: 108 GEYQCFARNKFGTA-LSNRIRLQVSKSPLWPK--ENLDPVVVQEGAPLTLQCNPPPGLPS 164
Query: 234 PVLRWFKDSRE 244
PV+ W S E
Sbjct: 165 PVIFWMSSSME 175
Score = 30.7 bits (66), Expect = 8.1
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 6/68 (8%)
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDV------FALTANAEDPTSLGTYTCEAVNCMGRA 277
LEC GVPTP + W+K ++ + AL G Y C A N MG
Sbjct: 260 LECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 319
Query: 278 YSSSKVHV 285
+ V V
Sbjct: 320 RHTISVRV 327
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 47.2 bits (107), Expect = 9e-05
Identities = 53/200 (26%), Positives = 80/200 (40%), Gaps = 18/200 (9%)
Query: 107 PPTFLR-RLQDLTVKVGTRTRFLVEIISSTECKVTWYRN-ERRLLEAERVSIVRDGSFFC 164
PP L R Q + V + RTR S + W++N + L+ + +GS
Sbjct: 440 PPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL-- 497
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQGTVS 223
G +TC A N+ G+A L V P + Y+ PE R TV
Sbjct: 498 -EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGT-----TVQ 551
Query: 224 LECKVVGVPTPVL--RWFKDSREIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGR 276
LEC+V P+ L W KD + G+ +LT G+YTC A + +
Sbjct: 552 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 611
Query: 277 AYSSSKVHVVGRASREGSLK 296
+ + + V+GR R L+
Sbjct: 612 DLAKAYLTVLGRPDRPRDLE 631
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/230 (23%), Positives = 89/230 (38%), Gaps = 20/230 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ D+G Y ASN GS R + V + +P D P ++L + G
Sbjct: 312 LRITNVSEEDSGEYFCLASNKMGS--IRHTISVRVKAAPYWLDEP------KNLILAPGE 363
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R + + + V W N L A + R+ + + C
Sbjct: 364 DGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAGDTIIFRDTQISSRAVYQCNTS 422
Query: 184 NVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G +A ++VL VP P + +R +L + L+C G P P LRWFK+
Sbjct: 423 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 479
Query: 243 R--EIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+ + G+ +L G YTC A N +G+A + ++ V
Sbjct: 480 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 529
Score = 31.5 bits (68), Expect = 4.6
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVV-GVPT 233
G + C A N G A S + + V K+ P+ E L ++ ++G ++L+C G+P+
Sbjct: 108 GEYQCFARNKFGTA-LSNRIRLQVSKSPLWPK--ENLDPVVVQEGAPLTLQCNPPPGLPS 164
Query: 234 PVLRWFKDSRE 244
PV+ W S E
Sbjct: 165 PVIFWMSSSME 175
Score = 30.7 bits (66), Expect = 8.1
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 6/68 (8%)
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDV------FALTANAEDPTSLGTYTCEAVNCMGRA 277
LEC GVPTP + W+K ++ + AL G Y C A N MG
Sbjct: 277 LECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 336
Query: 278 YSSSKVHV 285
+ V V
Sbjct: 337 RHTISVRV 344
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell
adhesion molecule isoform CHD2-42 precursor variant
protein.
Length = 2023
Score = 47.2 bits (107), Expect = 9e-05
Identities = 51/184 (27%), Positives = 72/184 (39%), Gaps = 13/184 (7%)
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVT---WYRNERRLLEAERVSIVRDGSFFCXXXXX 169
R++D G F I SS E +T W ++ L+ R I G+ +
Sbjct: 140 RVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQN 199
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVE--ELRALLTEQGTVSLEC 226
R G R S SA L V P A P ++ E R + Q V L C
Sbjct: 200 EDGLYNYRCITRHRYTGETRQSNSARLFVSDP-ANSAPSILDGFEHRKAMAGQ-RVELPC 257
Query: 227 KVVGVPTPVLRWFKDSREIKAGDVFALTANA---ED--PTSLGTYTCEAVNCMGRAYSSS 281
K +G P P RW KD+ ++ F T E+ P+ G+Y CE N G A
Sbjct: 258 KALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIG 317
Query: 282 KVHV 285
+++V
Sbjct: 318 RLYV 321
Score = 46.4 bits (105), Expect = 2e-04
Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 28/286 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S+++ D GVY A+N+AG + R+ V P +R ++++T G
Sbjct: 480 LNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---------PASIRPMKNITAIAGR 530
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T +I + WY+N LL + + + G +TC
Sbjct: 531 DTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNV- 588
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV-LRWFKD 241
V + S S ++V V K P F++ G V + C VV P+ + W KD
Sbjct: 589 LVQPQLSTSQSVHVTV----KVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 644
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
R I G + N + +SL ++ + ++ + + A E + + S
Sbjct: 645 GRPI-PGSLGVTIDNIDFTSSL------RISNLSLMHNGNYTCI---ARNEAAAVEHQSQ 694
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
L PP F + DQ + L+C P P ++VW +G
Sbjct: 695 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVP-TIVWKFSKG 739
Score = 31.9 bits (69), Expect = 3.5
Identities = 11/21 (52%), Positives = 15/21 (71%)
Query: 222 VSLECKVVGVPTPVLRWFKDS 242
+ L CK VG P+P ++W KDS
Sbjct: 1314 IVLPCKAVGDPSPAVKWMKDS 1334
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 47.2 bits (107), Expect = 9e-05
Identities = 53/200 (26%), Positives = 80/200 (40%), Gaps = 18/200 (9%)
Query: 107 PPTFLR-RLQDLTVKVGTRTRFLVEIISSTECKVTWYRN-ERRLLEAERVSIVRDGSFFC 164
PP L R Q + V + RTR S + W++N + L+ + +GS
Sbjct: 237 PPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL-- 294
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQGTVS 223
G +TC A N+ G+A L V P + Y+ PE R TV
Sbjct: 295 -EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGT-----TVQ 348
Query: 224 LECKVVGVPTPVL--RWFKDSREIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGR 276
LEC+V P+ L W KD + G+ +LT G+YTC A + +
Sbjct: 349 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 408
Query: 277 AYSSSKVHVVGRASREGSLK 296
+ + + V+GR R L+
Sbjct: 409 DLAKAYLTVLGRPDRPRDLE 428
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/230 (23%), Positives = 89/230 (38%), Gaps = 20/230 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ D+G Y ASN GS R + V + +P D P ++L + G
Sbjct: 109 LRITNVSEEDSGEYFCLASNKMGS--IRHTISVRVKAAPYWLDEP------KNLILAPGE 160
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R + + + V W N L A + R+ + + C
Sbjct: 161 DGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAGDTIIFRDTQISSRAVYQCNTS 219
Query: 184 NVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G +A ++VL VP P + +R +L + L+C G P P LRWFK+
Sbjct: 220 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 276
Query: 243 R--EIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+ + G+ +L G YTC A N +G+A + ++ V
Sbjct: 277 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 326
Score = 30.7 bits (66), Expect = 8.1
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 6/68 (8%)
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDV------FALTANAEDPTSLGTYTCEAVNCMGRA 277
LEC GVPTP + W+K ++ + AL G Y C A N MG
Sbjct: 74 LECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 133
Query: 278 YSSSKVHV 285
+ V V
Sbjct: 134 RHTISVRV 141
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 47.2 bits (107), Expect = 9e-05
Identities = 53/200 (26%), Positives = 80/200 (40%), Gaps = 18/200 (9%)
Query: 107 PPTFLR-RLQDLTVKVGTRTRFLVEIISSTECKVTWYRN-ERRLLEAERVSIVRDGSFFC 164
PP L R Q + V + RTR S + W++N + L+ + +GS
Sbjct: 493 PPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL-- 550
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVP-KAYKRPEFVEELRALLTEQGTVS 223
G +TC A N+ G+A L V P + Y+ PE R TV
Sbjct: 551 -EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGT-----TVQ 604
Query: 224 LECKVVGVPTPVL--RWFKDSREIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGR 276
LEC+V P+ L W KD + G+ +LT G+YTC A + +
Sbjct: 605 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 664
Query: 277 AYSSSKVHVVGRASREGSLK 296
+ + + V+GR R L+
Sbjct: 665 DLAKAYLTVLGRPDRPRDLE 684
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/230 (23%), Positives = 89/230 (38%), Gaps = 20/230 (8%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L ++ D+G Y ASN GS R + V + +P D P ++L + G
Sbjct: 365 LRITNVSEEDSGEYFCLASNKMGS--IRHTISVRVKAAPYWLDEP------KNLILAPGE 416
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
R + + + V W N L A + R+ + + C
Sbjct: 417 DGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAGDTIIFRDTQISSRAVYQCNTS 475
Query: 184 NVGGRASCSAHLNVL-VPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDS 242
N G +A ++VL VP P + +R +L + L+C G P P LRWFK+
Sbjct: 476 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 532
Query: 243 R--EIKAGDVF-----ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHV 285
+ + G+ +L G YTC A N +G+A + ++ V
Sbjct: 533 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 582
Score = 31.5 bits (68), Expect = 4.6
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVV-GVPT 233
G + C A N G A S + + V K+ P+ E L ++ ++G ++L+C G+P+
Sbjct: 161 GEYQCFARNKFGTA-LSNRIRLQVSKSPLWPK--ENLDPVVVQEGAPLTLQCNPPPGLPS 217
Query: 234 PVLRWFKDSRE 244
PV+ W S E
Sbjct: 218 PVIFWMSSSME 228
Score = 30.7 bits (66), Expect = 8.1
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 6/68 (8%)
Query: 224 LECKVVGVPTPVLRWFKDSREIKAGDV------FALTANAEDPTSLGTYTCEAVNCMGRA 277
LEC GVPTP + W+K ++ + AL G Y C A N MG
Sbjct: 330 LECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 389
Query: 278 YSSSKVHV 285
+ V V
Sbjct: 390 RHTISVRV 397
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 46.8 bits (106), Expect = 1e-04
Identities = 68/274 (24%), Positives = 100/274 (36%), Gaps = 46/274 (16%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G + S + + VY ASN G A + V AE PP L L
Sbjct: 409 GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE-------PPRILTPANTLYQV 461
Query: 121 VGTRTRFL-VEIISSTECKVTWYRNERRLLEAERVSI--------VRDGSFFCXXXXXXX 171
+ R L S + W++ + E + + ++D ++
Sbjct: 462 IANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIKDATWIVKEIPVAQ 521
Query: 172 XXXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGV 231
G +TC A N G A HL +PE+ A++ VS ECKV
Sbjct: 522 KDSTGTYTCVARNKLGMAKNEVHL---------QPEY-----AVVQRGSMVSFECKVKHD 567
Query: 232 PTPVLR--WFKDSREIKAGDVFA------LTANAEDPTSLGTYTCEAVNCMGRAYSSSKV 283
T L W KD+RE+ + + F + A+ D S GTYTC A + +S+ +
Sbjct: 568 HTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDS-GTYTCVANTTLDSVSASAVL 626
Query: 284 HVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQ 317
VV P + + P P F EL DQ
Sbjct: 627 SVVAPT-------PTPAPVYDVPNPPFDLELTDQ 653
Score = 37.1 bits (82), Expect = 0.093
Identities = 54/232 (23%), Positives = 89/232 (38%), Gaps = 34/232 (14%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
D+G Y A NA G+ + + V A P ++ Q+L + G +
Sbjct: 329 DSGNYQCIAKNALGAIHHTISVRVKAA--------PYWITAPQNLVLSPGEDGTLICRAN 380
Query: 133 SSTECKVTWYRNERRL-LEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+ + +++W N + + + S DG + C A N G
Sbjct: 381 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAV--YQCNASNEYGYLLA 438
Query: 192 SAHLNVLV-PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSR-EIKAGD 249
+A +NVL P P L ++ + + L+C G P P + WFK ++ D
Sbjct: 439 NAFVNVLAEPPRILTP--ANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 495
Query: 250 VFAL----TANAEDPT------------SLGTYTCEAVNCMGRAYSSSKVHV 285
++ L T +D T S GTYTC A N +G A ++VH+
Sbjct: 496 IYVLHENGTLEIKDATWIVKEIPVAQKDSTGTYTCVARNKLGMA--KNEVHL 545
Score = 33.5 bits (73), Expect = 1.1
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 222 VSLECKVVGVPTPVLRWFKD------SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMG 275
+SLEC G+PTP++ W K+ +R + L G Y C A N +G
Sbjct: 283 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 342
Query: 276 RAYSSSKVHVVGRASREGSLKPNSSGLSP 304
+ + V V +A+ P + LSP
Sbjct: 343 AIHHTISVRV--KAAPYWITAPQNLVLSP 369
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 18/162 (11%)
Query: 139 VTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCSAHLNV- 197
+TWY+ + ++E E+++ R + G + C A N G S +L V
Sbjct: 17 ITWYK-DAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT 75
Query: 198 -LVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDV----FA 252
+ P + P L + + + +V L C+ G P P + W K R + +G V F
Sbjct: 76 SIAPNITRGP-----LDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFT 130
Query: 253 LTANAE---DPTSL---GTYTCEAVNCMGRAYSSSKVHVVGR 288
+ PT + GTYTC A N G +S+ + V R
Sbjct: 131 PLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR 172
Score = 39.5 bits (88), Expect = 0.018
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 16/148 (10%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S D G YT A+N+ G D A L V A + PP QD +V GT
Sbjct: 137 LLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRIT--KPP------QDQSVIKGT 188
Query: 124 RTRFLVEIISSTECKVTW-YRNERRLLEAE---RVSIVRDGSFFCXXXXXXXXXXXGRWT 179
+ + + + + + + L E R+ + R+GS G +T
Sbjct: 189 QASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSL---HISQTWSGDIGTYT 245
Query: 180 CTAENVGGRASCSAHLNV-LVPKAYKRP 206
C + GG S SAHL V +P A + P
Sbjct: 246 CRVISAGGNDSRSAHLRVRQLPHAPEHP 273
Score = 37.9 bits (84), Expect = 0.053
Identities = 58/236 (24%), Positives = 85/236 (36%), Gaps = 28/236 (11%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S DTG++ A NAAG L V++ P R D TV G
Sbjct: 42 LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA-------PNITRGPLDSTVIDGM 94
Query: 124 RTRFLVEIISSTECKVTWYRNERRL----LEAERVSIVRDGSFFCXXXXXXXXXXXGRWT 179
E + +TW + ER L ++ R + + GS G +T
Sbjct: 95 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDA---GTYT 151
Query: 180 CTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR-- 237
C A N G SA L V +P ++ + Q S+ C V P +R
Sbjct: 152 CLATNSRGVDEASADLVVWARTRITKPP--QDQSVIKGTQA--SMVCGVTHDPRVTIRYI 207
Query: 238 WFKDSREI--KAGDVFALTANAEDPTS------LGTYTCEAVNCMGRAYSSSKVHV 285
W KD + ++ L N S +GTYTC ++ G S+ + V
Sbjct: 208 WEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 263
Score = 31.1 bits (67), Expect = 6.1
Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 222 VSLECKVVGVPTPVLRWFKDSREIKAGDVF--------ALTANAEDPTSLGTYTCEAVNC 273
V + C+ GVP P + W+KD+ ++ + L + P G + C A N
Sbjct: 3 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNA 62
Query: 274 MGRAYSSSKVHVVGRA 289
G +S+ + V A
Sbjct: 63 AGEVQTSTYLAVTSIA 78
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN+ G+ A + V +A+ PE+VE + + G+ + C G P P
Sbjct: 306 GIYECEAENIRGKDKHQARIYV---QAF--PEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA 289
+RW K+ G++ E + G Y C A N G Y+++++ ++ A
Sbjct: 361 TIRWLKNGYAYHKGELRLYDVTFE---NAGMYQCIAENTYGAIYANAELKILALA 412
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/228 (24%), Positives = 84/228 (36%), Gaps = 31/228 (13%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + + D G+Y +A N G D + R+ V A P ++ + D V
Sbjct: 292 GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF--------PEWVEHINDTEVD 343
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+G+ + + W +N + E + D +F G + C
Sbjct: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHKGELR--LYDVTF----------ENAGMYQC 391
Query: 181 TAENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
AEN G +A L +L P P + + L + G V +ECK P P W
Sbjct: 392 IAENTYGAIYANAELKILALAPTFEMNPM---KKKILAAKGGRVIIECKPKAAPKPKFSW 448
Query: 239 FK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
K +S I + +L N G YTC A N G+A S+
Sbjct: 449 SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
Score = 32.7 bits (71), Expect = 2.0
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 7/70 (10%)
Query: 222 VSLECKVVGVPTPVLRWFK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMG 275
V+LEC +G P P +RW K + EI N + G Y CEA N G
Sbjct: 259 VTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE-GIYECEAENIRG 317
Query: 276 RAYSSSKVHV 285
+ ++++V
Sbjct: 318 KDKHQARIYV 327
Score = 32.7 bits (71), Expect = 2.0
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
+ G+Y A N G+ A L++ A +P+ E P + + L K G R +
Sbjct: 385 NAGMYQCIAENTYGAIYANAELKILAL-APTFEMNPM---KKKILAAK-GGRVIIECKPK 439
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
++ + K +W + L+ + R+ I DGS G +TC AEN G+A+ +
Sbjct: 440 AAPKPKFSWSKGTEWLVNSSRILIWEDGSL---EINNITRNDGGIYTCFAENNRGKANST 496
Query: 193 AHLNVLVP 200
L + P
Sbjct: 497 GTLVITDP 504
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN+ G+ A + V +A+ PE+VE + + G+ + C G P P
Sbjct: 295 GIYECEAENIRGKDKHQARIYV---QAF--PEWVEHINDTEVDIGSDLYWPCVATGKPIP 349
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA 289
+RW K+ G++ E + G Y C A N G Y+++++ ++ A
Sbjct: 350 TIRWLKNGYAYHKGELRLYDVTFE---NAGMYQCIAENTYGAIYANAELKILALA 401
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/228 (24%), Positives = 84/228 (36%), Gaps = 31/228 (13%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + + D G+Y +A N G D + R+ V A P ++ + D V
Sbjct: 281 GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF--------PEWVEHINDTEVD 332
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+G+ + + W +N + E + D +F G + C
Sbjct: 333 IGSDLYWPCVATGKPIPTIRWLKNGYAYHKGELR--LYDVTF----------ENAGMYQC 380
Query: 181 TAENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
AEN G +A L +L P P + + L + G V +ECK P P W
Sbjct: 381 IAENTYGAIYANAELKILALAPTFEMNPM---KKKILAAKGGRVIIECKPKAAPKPKFSW 437
Query: 239 FK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
K +S I + +L N G YTC A N G+A S+
Sbjct: 438 SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 485
Score = 32.7 bits (71), Expect = 2.0
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 7/70 (10%)
Query: 222 VSLECKVVGVPTPVLRWFK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMG 275
V+LEC +G P P +RW K + EI N + G Y CEA N G
Sbjct: 248 VTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE-GIYECEAENIRG 306
Query: 276 RAYSSSKVHV 285
+ ++++V
Sbjct: 307 KDKHQARIYV 316
Score = 32.7 bits (71), Expect = 2.0
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
+ G+Y A N G+ A L++ A +P+ E P + + L K G R +
Sbjct: 374 NAGMYQCIAENTYGAIYANAELKILAL-APTFEMNPM---KKKILAAK-GGRVIIECKPK 428
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
++ + K +W + L+ + R+ I DGS G +TC AEN G+A+ +
Sbjct: 429 AAPKPKFSWSKGTEWLVNSSRILIWEDGSL---EINNITRNDGGIYTCFAENNRGKANST 485
Query: 193 AHLNVLVP 200
L + P
Sbjct: 486 GTLVITDP 493
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN+ G+ A + V +A+ PE+VE + + G+ + C G P P
Sbjct: 306 GIYECEAENIRGKDKHQARIYV---QAF--PEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA 289
+RW K+ G++ E + G Y C A N G Y+++++ ++ A
Sbjct: 361 TIRWLKNGYAYHKGELRLYDVTFE---NAGMYQCIAENTYGAIYANAELKILALA 412
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/228 (24%), Positives = 84/228 (36%), Gaps = 31/228 (13%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + + D G+Y +A N G D + R+ V A P ++ + D V
Sbjct: 292 GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF--------PEWVEHINDTEVD 343
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+G+ + + W +N + E + D +F G + C
Sbjct: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHKGELR--LYDVTF----------ENAGMYQC 391
Query: 181 TAENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
AEN G +A L +L P P + + L + G V +ECK P P W
Sbjct: 392 IAENTYGAIYANAELKILALAPTFEMNPM---KKKILAAKGGRVIIECKPKAAPKPKFSW 448
Query: 239 FK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
K +S I + +L N G YTC A N G+A S+
Sbjct: 449 SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
Score = 32.7 bits (71), Expect = 2.0
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 7/70 (10%)
Query: 222 VSLECKVVGVPTPVLRWFK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMG 275
V+LEC +G P P +RW K + EI N + G Y CEA N G
Sbjct: 259 VTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE-GIYECEAENIRG 317
Query: 276 RAYSSSKVHV 285
+ ++++V
Sbjct: 318 KDKHQARIYV 327
Score = 32.7 bits (71), Expect = 2.0
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
+ G+Y A N G+ A L++ A +P+ E P + + L K G R +
Sbjct: 385 NAGMYQCIAENTYGAIYANAELKILAL-APTFEMNPM---KKKILAAK-GGRVIIECKPK 439
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
++ + K +W + L+ + R+ I DGS G +TC AEN G+A+ +
Sbjct: 440 AAPKPKFSWSKGTEWLVNSSRILIWEDGSL---EINNITRNDGGIYTCFAENNRGKANST 496
Query: 193 AHLNVLVP 200
L + P
Sbjct: 497 GTLVITDP 504
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 176 GRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGVPTP 234
G + C AEN+ G+ A + V +A+ PE+VE + + G+ + C G P P
Sbjct: 306 GIYECEAENIRGKDKHQARIYV---QAF--PEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
Query: 235 VLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRA 289
+RW K+ G++ E + G Y C A N G Y+++++ ++ A
Sbjct: 361 TIRWLKNGYAYHKGELRLYDVTFE---NAGMYQCIAENTYGAIYANAELKILALA 412
Score = 44.8 bits (101), Expect = 5e-04
Identities = 55/228 (24%), Positives = 84/228 (36%), Gaps = 31/228 (13%)
Query: 61 GVRLTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVK 120
G L + + D G+Y +A N G D + R+ V A P ++ + D V
Sbjct: 292 GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF--------PEWVEHINDTEVD 343
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
+G+ + + W +N + E + D +F G + C
Sbjct: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHKGELR--LYDVTF----------ENAGMYQC 391
Query: 181 TAENVGGRASCSAHLNVLV--PKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRW 238
AEN G +A L +L P P + + L + G V +ECK P P W
Sbjct: 392 IAENTYGAIYANAELKILALAPTFEMNPM---KKKILAAKGGRVIIECKPKAAPKPKFSW 448
Query: 239 FK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSS 280
K +S I + +L N G YTC A N G+A S+
Sbjct: 449 SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
Score = 32.7 bits (71), Expect = 2.0
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 7/70 (10%)
Query: 222 VSLECKVVGVPTPVLRWFK------DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMG 275
V+LEC +G P P +RW K + EI N + G Y CEA N G
Sbjct: 259 VTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE-GIYECEAENIRG 317
Query: 276 RAYSSSKVHV 285
+ ++++V
Sbjct: 318 KDKHQARIYV 327
Score = 32.7 bits (71), Expect = 2.0
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 73 DTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGTRTRFLVEII 132
+ G+Y A N G+ A L++ A +P+ E P + + L K G R +
Sbjct: 385 NAGMYQCIAENTYGAIYANAELKILAL-APTFEMNPM---KKKILAAK-GGRVIIECKPK 439
Query: 133 SSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASCS 192
++ + K +W + L+ + R+ I DGS G +TC AEN G+A+ +
Sbjct: 440 AAPKPKFSWSKGTEWLVNSSRILIWEDGSL---EINNITRNDGGIYTCFAENNRGKANST 496
Query: 193 AHLNVLVP 200
L + P
Sbjct: 497 GTLVITDP 504
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 46.4 bits (105), Expect = 2e-04
Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 28/286 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S+++ D GVY A+N+AG + R+ V P +R ++++T G
Sbjct: 299 LNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---------PASIRPMKNITAIAGR 349
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T +I + WY+N LL + + + G +TC
Sbjct: 350 DTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNV- 407
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV-LRWFKD 241
V + S S ++V V K P F++ G V + C VV P+ + W KD
Sbjct: 408 LVQPQLSTSQSVHVTV----KVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 463
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
R I G + N + +SL ++ + ++ + + A E + + S
Sbjct: 464 GRPI-PGSLGVTIDNIDFTSSL------RISNLSLMHNGNYTCI---ARNEAAAVEHQSQ 513
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
L PP F + DQ + L+C P P ++VW +G
Sbjct: 514 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVP-TIVWKFSKG 558
Score = 41.1 bits (92), Expect = 0.006
Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 188 RASCSAHLNVLVPKAYKRPEFVE--ELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREI 245
R S SA L V P A P ++ + R + Q V L CK +G P P RW KD+ +
Sbjct: 38 RQSNSARLFVSDP-ANSAPSILDGFDHRKAMAGQ-RVELPCKALGHPEPDYRWLKDNMPL 95
Query: 246 KAGDVFALTANA---ED--PTSLGTYTCEAVNCMGRAYSSSKVHV 285
+ F T E+ P+ G+Y CE N G A +++V
Sbjct: 96 ELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 140
>AK023854-1|BAB14704.1| 442|Homo sapiens .117). protein.
Length = 442
Score = 46.4 bits (105), Expect = 2e-04
Identities = 58/226 (25%), Positives = 83/226 (36%), Gaps = 25/226 (11%)
Query: 132 ISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAENVGGRASC 191
+S + V WY++ + E+E + + RDG G + C A G S
Sbjct: 4 LSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA----GDDSA 59
Query: 192 SAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLRWFKDSREIKAGDVF 251
+ V P L G V L C+V + V RW+KD E++A D
Sbjct: 60 FFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQV-RWYKDGLEVEASD-- 116
Query: 252 ALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFT 311
AL AE PT T G ++ + + + EPP F
Sbjct: 117 ALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAI-----------TFNVILAEPPVQFL 165
Query: 312 RELEDQYVRIC----EPFTLSCQIVVPPWPRSVVWYNKEGKVEAGE 353
LE +C EP LSC++ P VVW + G V+ GE
Sbjct: 166 -ALETTPSPLCVAPGEPVVLSCELSRAGAP--VVWSHNGGPVQEGE 208
Score = 33.9 bits (74), Expect = 0.87
Identities = 55/221 (24%), Positives = 86/221 (38%), Gaps = 32/221 (14%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLT---VK 120
L + A G+YT Q+ A G+ + ++V+ P ++ + DLT V
Sbjct: 221 LCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAE---------PLLVKLVSDLTPLTVH 271
Query: 121 VGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTC 180
G F E+ S + VTW RN + +V + ++GS G T
Sbjct: 272 EGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTL 330
Query: 181 TAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGV-PTPVLRW 238
A G + SA L+V + F+ L+ + E+G V LE + V +RW
Sbjct: 331 RA----GSTATSARLHVRETELL----FLRRLQDVRAEEGQDVCLEMETGRVGAAGAVRW 382
Query: 239 FK-------DSREIKA--GDVFALTANAEDPTSLGTYTCEA 270
+ DSR A G + L + GTY CE+
Sbjct: 383 VRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCES 423
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell
adhesion molecule splice variant protein.
Length = 1746
Score = 46.4 bits (105), Expect = 2e-04
Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 28/286 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S+++ D GVY A+N+AG + R+ V P +R ++++T G
Sbjct: 221 LNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---------PASIRPMKNITAIAGR 271
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T +I + WY+N LL + + + G +TC
Sbjct: 272 DTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNV- 329
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV-LRWFKD 241
V + S S ++V V K P F++ G V + C VV P+ + W KD
Sbjct: 330 LVQPQLSTSQSVHVTV----KVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 385
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
R I G + N + +SL ++ + ++ + + A E + + S
Sbjct: 386 GRPI-PGSLGVTIDNIDFTSSL------RISNLSLMHNGNYTCI---ARNEAAAVEHQSQ 435
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
L PP F + DQ + L+C P P ++VW +G
Sbjct: 436 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVP-TIVWKFSKG 480
Score = 31.9 bits (69), Expect = 3.5
Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 5/62 (8%)
Query: 229 VGVPTPVLRWFKDSREIKAGDVFALTANA---ED--PTSLGTYTCEAVNCMGRAYSSSKV 283
+G P P RW KD+ ++ F T E+ P+ G+Y CE N G A ++
Sbjct: 1 LGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRL 60
Query: 284 HV 285
+V
Sbjct: 61 YV 62
Score = 31.9 bits (69), Expect = 3.5
Identities = 11/21 (52%), Positives = 15/21 (71%)
Query: 222 VSLECKVVGVPTPVLRWFKDS 242
+ L CK VG P+P ++W KDS
Sbjct: 1055 IVLPCKAVGDPSPAVKWMKDS 1075
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 2012
Score = 46.4 bits (105), Expect = 2e-04
Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 28/286 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S+++ D GVY A+N+AG + R+ V P +R ++++T G
Sbjct: 469 LNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---------PASIRPMKNITAIAGR 519
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T +I + WY+N LL + + + G +TC
Sbjct: 520 DTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNV- 577
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV-LRWFKD 241
V + S S ++V V K P F++ G V + C VV P+ + W KD
Sbjct: 578 LVQPQLSTSQSVHVTV----KVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 633
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
R I G + N + +SL ++ + ++ + + A E + + S
Sbjct: 634 GRPI-PGSLGVTIDNIDFTSSL------RISNLSLMHNGNYTCI---ARNEAAAVEHQSQ 683
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
L PP F + DQ + L+C P P ++VW +G
Sbjct: 684 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVP-TIVWKFSKG 728
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/184 (27%), Positives = 72/184 (39%), Gaps = 13/184 (7%)
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVT---WYRNERRLLEAERVSIVRDGSFFCXXXXX 169
R++D G F I SS E +T W ++ L+ R I G+ +
Sbjct: 129 RVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQN 188
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVE--ELRALLTEQGTVSLEC 226
R G R S SA L V P A P ++ + R + Q V L C
Sbjct: 189 EDGLYNYRCITRHRYTGETRQSNSARLFVSDP-ANSAPSILDGFDHRKAMAGQ-RVELPC 246
Query: 227 KVVGVPTPVLRWFKDSREIKAGDVFALTANA---ED--PTSLGTYTCEAVNCMGRAYSSS 281
K +G P P RW KD+ ++ F T E+ P+ G+Y CE N G A
Sbjct: 247 KALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIG 306
Query: 282 KVHV 285
+++V
Sbjct: 307 RLYV 310
Score = 31.9 bits (69), Expect = 3.5
Identities = 11/21 (52%), Positives = 15/21 (71%)
Query: 222 VSLECKVVGVPTPVLRWFKDS 242
+ L CK VG P+P ++W KDS
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDS 1323
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1571
Score = 46.4 bits (105), Expect = 2e-04
Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 28/286 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S+++ D GVY A+N+AG + R+ V P +R ++++T G
Sbjct: 469 LNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---------PASIRPMKNITAIAGR 519
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T +I + WY+N LL + + + G +TC
Sbjct: 520 DTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNV- 577
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV-LRWFKD 241
V + S S ++V V K P F++ G V + C VV P+ + W KD
Sbjct: 578 LVQPQLSTSQSVHVTV----KVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 633
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
R I G + N + +SL ++ + ++ + + A E + + S
Sbjct: 634 GRPI-PGSLGVTIDNIDFTSSL------RISNLSLMHNGNYTCI---ARNEAAAVEHQSQ 683
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
L PP F + DQ + L+C P P ++VW +G
Sbjct: 684 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVP-TIVWKFSKG 728
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/184 (27%), Positives = 72/184 (39%), Gaps = 13/184 (7%)
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVT---WYRNERRLLEAERVSIVRDGSFFCXXXXX 169
R++D G F I SS E +T W ++ L+ R I G+ +
Sbjct: 129 RVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQN 188
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVE--ELRALLTEQGTVSLEC 226
R G R S SA L V P A P ++ + R + Q V L C
Sbjct: 189 EDGLYNYRCITRHRYTGETRQSNSARLFVSDP-ANSAPSILDGFDHRKAMAGQ-RVELPC 246
Query: 227 KVVGVPTPVLRWFKDSREIKAGDVFALTANA---ED--PTSLGTYTCEAVNCMGRAYSSS 281
K +G P P RW KD+ ++ F T E+ P+ G+Y CE N G A
Sbjct: 247 KALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIG 306
Query: 282 KVHV 285
+++V
Sbjct: 307 RLYV 310
Score = 31.9 bits (69), Expect = 3.5
Identities = 11/21 (52%), Positives = 15/21 (71%)
Query: 222 VSLECKVVGVPTPVLRWFKDS 242
+ L CK VG P+P ++W KDS
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDS 1323
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1896
Score = 46.4 bits (105), Expect = 2e-04
Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 28/286 (9%)
Query: 64 LTVSTARTGDTGVYTLQASNAAGSDTARVRLEVSAEESPSGEDPPTFLRRLQDLTVKVGT 123
L +S+++ D GVY A+N+AG + R+ V P +R ++++T G
Sbjct: 455 LNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG---------PASIRPMKNITAIAGR 505
Query: 124 RTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGRWTCTAE 183
T +I + WY+N LL + + + G +TC
Sbjct: 506 DTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNV- 563
Query: 184 NVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPV-LRWFKD 241
V + S S ++V V K P F++ G V + C VV P+ + W KD
Sbjct: 564 LVQPQLSTSQSVHVTV----KVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 619
Query: 242 SREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSLKPNSSG 301
R I G + N + +SL ++ + ++ + + A E + + S
Sbjct: 620 GRPI-PGSLGVTIDNIDFTSSL------RISNLSLMHNGNYTCI---ARNEAAAVEHQSQ 669
Query: 302 LSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVWYNKEG 347
L PP F + DQ + L+C P P ++VW +G
Sbjct: 670 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVP-TIVWKFSKG 714
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/184 (27%), Positives = 72/184 (39%), Gaps = 13/184 (7%)
Query: 113 RLQDLTVKVGTRTRFLVEIISSTECKVT---WYRNERRLLEAERVSIVRDGSFFCXXXXX 169
R++D G F I SS E +T W ++ L+ R I G+ +
Sbjct: 115 RVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQN 174
Query: 170 XXXXXXGRWTCTAENVGG-RASCSAHLNVLVPKAYKRPEFVE--ELRALLTEQGTVSLEC 226
R G R S SA L V P A P ++ + R + Q V L C
Sbjct: 175 EDGLYNYRCITRHRYTGETRQSNSARLFVSDP-ANSAPSILDGFDHRKAMAGQ-RVELPC 232
Query: 227 KVVGVPTPVLRWFKDSREIKAGDVFALTANA---ED--PTSLGTYTCEAVNCMGRAYSSS 281
K +G P P RW KD+ ++ F T E+ P+ G+Y CE N G A
Sbjct: 233 KALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIG 292
Query: 282 KVHV 285
+++V
Sbjct: 293 RLYV 296
Score = 31.9 bits (69), Expect = 3.5
Identities = 11/21 (52%), Positives = 15/21 (71%)
Query: 222 VSLECKVVGVPTPVLRWFKDS 242
+ L CK VG P+P ++W KDS
Sbjct: 1289 IVLPCKAVGDPSPAVKWMKDS 1309
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 46.0 bits (104), Expect = 2e-04
Identities = 56/227 (24%), Positives = 80/227 (35%), Gaps = 15/227 (6%)
Query: 118 TVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXGR 177
T + G F S E ++W+RN + + E E+ + GS G
Sbjct: 221 TAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKY--ILKGSNTELTVRNIINSDGGP 278
Query: 178 WTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGTVSLECKVVGVPTPVLR 237
+ C A N G A L V V +P ++ E G V+L C G P P +
Sbjct: 279 YVCRATNKAGEDEKQAFLQVFV-----QPHIIQLKNETTYENGQVTLVCDAEGEPIPEIT 333
Query: 238 WFK--DSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
W + D GD +L E G + +++ S S + ASR G
Sbjct: 334 WKRAVDGFTFTEGDK-SLDGRIE---VKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGG- 388
Query: 296 KPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVVPPWPRSVVW 342
S L E P F Y P +SC + P P S+ W
Sbjct: 389 HQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNP-PASIHW 434
Score = 43.6 bits (98), Expect = 0.001
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 27/237 (11%)
Query: 52 RFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAG-SDTARVRLEVSAEESPSGEDPPTF 110
R V +E RLT+ A D G+Y QA++A G + A V LE+ + TF
Sbjct: 66 RVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKL--------TF 117
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTW-YRNER-RLLEAERVSIVRDGSFFCXXXX 168
+ K G + + SS V+W Y NE + R +++ + +
Sbjct: 118 REVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNL---QIL 174
Query: 169 XXXXXXXGRWTCTAENVGGRASCSAH---LNVLVPKAYKRPEFVEELRALLTEQGTVSLE 225
G + C V R + V VP A P+ A E+ T S
Sbjct: 175 NINKSDEGIYRCEGR-VEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFS-- 231
Query: 226 CKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPT-------SLGTYTCEAVNCMG 275
C+ G P P + WF++ + I+ + + L + + T G Y C A N G
Sbjct: 232 CRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAG 288
Score = 35.1 bits (77), Expect = 0.38
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 9/147 (6%)
Query: 114 LQDLTVKVGTRTRFLVEIISSTECKVTWYRNE-RRLLEAERVSIVRDGSFFCXXXXXXXX 172
L + + VG F I E + WY + +++ +RV + ++G
Sbjct: 27 LSKVELSVGESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANI 85
Query: 173 XXXGRWTCTAENVGGRASCSAHLNVLVPKAYKRPEFVEELRALLTEQGT-VSLECKVVGV 231
G + C A + G+ + +V + Y++ F E + +QG + C+V
Sbjct: 86 EDAGIYRCQATDAKGQTQEAT----VVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSS 141
Query: 232 PTPVLRWFKDSREIK--AGDVFALTAN 256
P P + W + E+ + + FA+ AN
Sbjct: 142 PAPAVSWLYHNEEVTTISDNRFAMLAN 168
>AB094146-1|BAC66178.1| 333|Homo sapiens secretory isoform of
TSLC-1 protein.
Length = 333
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 212 LRALLTEQGTVSLECKVVGVPTPVL-RWFKDSREIKAGDVFA---LTANAEDPTSLGTYT 267
L+ L E + L C+ +G P PV+ W + E+ V + L N + T GTY
Sbjct: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 312
Query: 268 CEAVNCMGRAYSSSKVHVVG 287
CEA N +G+A+S ++V G
Sbjct: 313 CEASNIVGKAHSDYMLYVYG 332
>X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein.
Length = 1142
Score = 45.6 bits (103), Expect = 3e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVF-------ALTANA 257
P+F+ L + G + +L C V G P P + W K+ EI+ F LT N
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1108
Query: 258 EDPTSL--GTYTCEAVNCMGRAYSSSKVHV 285
P+ GTYTC AVN +G A + K+ V
Sbjct: 1109 RRPSPFDAGTYTCRAVNELGEALAECKLEV 1138
Score = 34.7 bits (76), Expect = 0.50
Identities = 48/199 (24%), Positives = 74/199 (37%), Gaps = 26/199 (13%)
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
L+ + DLTVK + F E+ S + WY+N + ++R++I G F
Sbjct: 442 LQDIADLTVKASEQAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVL------VPKAYKRPEFVEELRALLTEQGTV-- 222
G +T + S SA LN L VPK + P+ + +E V
Sbjct: 501 RPEDEGDYTFVPDGYA-LGSLSAKLNFLEIKVEYVPKQ-EPPKIHLDCSGKTSENAIVVV 558
Query: 223 -----SLECKVVGVPTPVLRWFKD----------SREIKAGDVFALTANAEDPTSLGTYT 267
L+ + G P PV W K +R K D + + G YT
Sbjct: 559 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 618
Query: 268 CEAVNCMGRAYSSSKVHVV 286
+ N +G +S + VV
Sbjct: 619 IKVTNPVGEDVASIFLQVV 637
Score = 33.9 bits (74), Expect = 0.87
Identities = 24/94 (25%), Positives = 32/94 (34%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P FL L D V G + + KV W +N+ + E + I
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1108
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK 201
G +TC A N G A L V VP+
Sbjct: 1109 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1142
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/66 (28%), Positives = 30/66 (45%)
Query: 31 RHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTA 90
R H + ++ K++ D +F+ T G + L + D G YT +A N G A
Sbjct: 1073 RGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALA 1132
Query: 91 RVRLEV 96
+LEV
Sbjct: 1133 ECKLEV 1138
>BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein C,
fast type protein.
Length = 1141
Score = 45.6 bits (103), Expect = 3e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 206 PEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREIKAGDVF-------ALTANA 257
P+F+ L + G + +L C V G P P + W K+ EI+ F LT N
Sbjct: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
Query: 258 EDPTSL--GTYTCEAVNCMGRAYSSSKVHV 285
P+ GTYTC AVN +G A + K+ V
Sbjct: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
Score = 35.5 bits (78), Expect = 0.28
Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 27/199 (13%)
Query: 111 LRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXX 170
L+ + DLTVK + F E+ S + WY+N + ++R++I G F
Sbjct: 442 LQDIADLTVKASEQAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
Query: 171 XXXXXGRWTCTAENVGGRASCSAHLNVL------VPKAYKRPEFVEELRALLTEQGTV-- 222
G +T + G S SA LN L VPK + P+ + +E V
Sbjct: 501 RPEDEGDYTFVPD--GYALSLSAKLNFLEIKVEYVPKQ-EPPKIHLDCSGKTSENAIVVV 557
Query: 223 -----SLECKVVGVPTPVLRWFKD----------SREIKAGDVFALTANAEDPTSLGTYT 267
L+ + G P PV W K +R K D + + G YT
Sbjct: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
Query: 268 CEAVNCMGRAYSSSKVHVV 286
+ N +G +S + VV
Sbjct: 618 IKVTNPVGEDVASIFLQVV 636
Score = 33.9 bits (74), Expect = 0.87
Identities = 24/94 (25%), Positives = 32/94 (34%)
Query: 108 PTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXX 167
P FL L D V G + + KV W +N+ + E + I
Sbjct: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
Query: 168 XXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK 201
G +TC A N G A L V VP+
Sbjct: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/66 (28%), Positives = 30/66 (45%)
Query: 31 RHHVRAFILNTKSRAGASLDDRFVSTEEAGGVRLTVSTARTGDTGVYTLQASNAAGSDTA 90
R H + ++ K++ D +F+ T G + L + D G YT +A N G A
Sbjct: 1072 RGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALA 1131
Query: 91 RVRLEV 96
+LEV
Sbjct: 1132 ECKLEV 1137
>AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens
cDNA FLJ37794 fis, clone BRHIP3000488. ).
Length = 903
Score = 45.6 bits (103), Expect = 3e-04
Identities = 51/201 (25%), Positives = 80/201 (39%), Gaps = 12/201 (5%)
Query: 117 LTVKVGTRTRFLVEIISSTECKVTWYRNERRLLEAERVSIVRDGSFFCXXXXXXXXXXXG 176
+TVKVG V KVTWY++ + E ERVS+ R G
Sbjct: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
Query: 177 RWTCTAENVGGRASCSAHLNVLVPKAY-KRPEFVEELRALLTEQGTVSLECKVVGVPTPV 235
+N G A+ + HL+VL P + +P+ + + E T++ PV
Sbjct: 677 LILLKLKNDHGSATATLHLSVLEPPGFASQPQVTD----VTKEAVTITWNAPTQDGGAPV 732
Query: 236 LRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNCMGRAYSSSKVHVVGRASREGSL 295
L + + R K G + N +DP GT C + +V V +A
Sbjct: 733 LGYIVERR--KKGSNLWVPVN-KDPIQ-GT-KCTVDGLLEDTEYEFRVIAVNKAGPGQPS 787
Query: 296 KPNSSGLSPEP--PPIFTREL 314
P+SS ++ +P PP ++L
Sbjct: 788 VPSSSVVAKDPVKPPGLVQDL 808
>AC115538-1|AAY40987.1| 103|Homo sapiens unknown protein.
Length = 103
Score = 45.6 bits (103), Expect = 3e-04
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
Query: 107 PPTFLRRLQDLTVKVGTRTRFLVEIISSTECKVTWYR-NERRLLEAERVSIVRDG-SFFC 164
PP F+ +LQ+ V G R ++ ++ W + NE +RVS+ +D + C
Sbjct: 6 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 65
Query: 165 XXXXXXXXXXXGRWTCTAENVGGRASCSAHLNVLVPK 201
G +T +A+N G SC+A L+V + +
Sbjct: 66 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISR 102
Score = 39.1 bits (87), Expect = 0.023
Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 201 KAYKRPEFVEELRALLTEQG-TVSLECKVVGVPTPVLRWFKDSREI 245
+A+K P F+E+L+ G V LEC+V+GVP P + W K++ +
Sbjct: 2 EAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL 47
>U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase
protein.
Length = 882
Score = 45.2 bits (102), Expect = 4e-04
Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 8/136 (5%)
Query: 215 LLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNC 273
L QG V L C V G+ P ++W KD ++ D + + + +G + ++V
Sbjct: 44 LTVSQGQPVKLNCSVEGMEEPDIQWVKDGAVVQNLDQLYIPVSEQH--WIGFLSLKSVER 101
Query: 274 MGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVV 333
+V G + L+ E P FT E +D V PF LSC+ V
Sbjct: 102 SDAGRYWCQVEDGGETEISQPV-----WLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVG 156
Query: 334 PPWPRSVVWYNKEGKV 349
PP P ++VW+ K+
Sbjct: 157 PPEPVTIVWWRGTTKI 172
>U05682-1|AAA19236.1| 890|Homo sapiens Rse protein.
Length = 890
Score = 45.2 bits (102), Expect = 4e-04
Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 8/136 (5%)
Query: 215 LLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNC 273
L QG V L C V G+ P ++W KD ++ D + + + +G + ++V
Sbjct: 52 LTVSQGQPVKLNCSVEGMEEPDIQWVKDGAVVQNLDQLYIPVSEQH--WIGFLSLKSVER 109
Query: 274 MGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVV 333
+V G + L+ E P FT E +D V PF LSC+ V
Sbjct: 110 SDAGRYWCQVEDGGETEISQPV-----WLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVG 164
Query: 334 PPWPRSVVWYNKEGKV 349
PP P ++VW+ K+
Sbjct: 165 PPEPVTIVWWRGTTKI 180
>D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase
protein.
Length = 884
Score = 45.2 bits (102), Expect = 4e-04
Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 8/136 (5%)
Query: 215 LLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNC 273
L QG V L C V G+ P ++W KD ++ D + + + +G + ++V
Sbjct: 46 LTVSQGQPVKLNCSVEGMEEPDIQWVKDGAVVQNLDQLYIPVSEQH--WIGFLSLKSVER 103
Query: 274 MGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVV 333
+V G + L+ E P FT E +D V PF LSC+ V
Sbjct: 104 SDAGRYWCQVEDGGETEISQPV-----WLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVG 158
Query: 334 PPWPRSVVWYNKEGKV 349
PP P ++VW+ K+
Sbjct: 159 PPEPVTIVWWRGTTKI 174
>D17517-1|BAA04467.1| 890|Homo sapiens Sky protein.
Length = 890
Score = 45.2 bits (102), Expect = 4e-04
Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 8/136 (5%)
Query: 215 LLTEQGT-VSLECKVVGVPTPVLRWFKDSREIKAGDVFALTANAEDPTSLGTYTCEAVNC 273
L QG V L C V G+ P ++W KD ++ D + + + +G + ++V
Sbjct: 52 LTVSQGQPVKLNCSVEGMEEPDIQWVKDGAVVQNLDQLYIPVSEQH--WIGFLSLKSVER 109
Query: 274 MGRAYSSSKVHVVGRASREGSLKPNSSGLSPEPPPIFTRELEDQYVRICEPFTLSCQIVV 333
+V G + L+ E P FT E +D V PF LSC+ V
Sbjct: 110 SDAGRYWCQVEDGGETEISQPV-----WLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVG 164
Query: 334 PPWPRSVVWYNKEGKV 349
PP P ++VW+ K+
Sbjct: 165 PPEPVTIVWWRGTTKI 180
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.133 0.404
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 51,925,612
Number of Sequences: 224733
Number of extensions: 2106361
Number of successful extensions: 20395
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 385
Number of HSP's successfully gapped in prelim test: 388
Number of HSP's that attempted gapping in prelim test: 13737
Number of HSP's gapped (non-prelim): 4299
length of query: 354
length of database: 73,234,838
effective HSP length: 91
effective length of query: 263
effective length of database: 52,784,135
effective search space: 13882227505
effective search space used: 13882227505
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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