Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002018-TA|BGIBMGA002018-PA|IPR013032|EGF-like region,
IPR000034|Laminin B, IPR002049|EGF-like, laminin, IPR001791|Laminin G,
IPR008211|Laminin, N-terminal, IPR002016|Haem peroxidase,
plant/fungal/bacterial, IPR000276|Rhodopsin-like GPCR superfamily,
IPR008985|Concanavalin A-like lectin/glucanase,
IPR008979|Galactose-binding like, IPR008972|Cupredoxin, IPR006210|EGF,
IPR010307|Laminin II, IPR012680|Laminin G, subdomain 2
(3668 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain pr... 1702 0.0
AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein. 1697 0.0
AB067494-1|BAB67800.1| 1737|Homo sapiens KIAA1907 protein protein. 1268 0.0
AY327116-1|AAQ72571.1| 3277|Homo sapiens laminin alpha 3 splice ... 867 0.0
AY327115-1|AAQ72570.1| 3333|Homo sapiens laminin alpha 3 splice ... 867 0.0
AB107369-1|BAD13428.1| 3333|Homo sapiens laminin alpha 3b chain ... 867 0.0
AF005258-1|AAC51867.1| 1486|Homo sapiens laminin alpha 3b chain ... 608 e-172
X58531-1|CAA41418.1| 2628|Homo sapiens laminin A chain protein. 540 e-152
U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain pro... 517 e-145
Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)... 516 e-145
AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (meros... 516 e-145
AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (meros... 516 e-145
AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (meros... 516 e-145
AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (meros... 516 e-145
AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (meros... 516 e-145
AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (meros... 516 e-145
BC093406-1|AAH93406.1| 581|Homo sapiens LAMA3 protein protein. 505 e-141
BC085017-1|AAH85017.1| 561|Homo sapiens LAMA5 protein protein. 497 e-139
AL354836-6|CAI12295.1| 500|Homo sapiens laminin, alpha 5 protein. 497 e-139
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 442 e-123
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 442 e-123
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme... 441 e-122
AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (forme... 441 e-122
AY481573-1|AAS47698.1| 5202|Homo sapiens Usher syndrome 2A isofo... 414 e-114
AL513305-1|CAH73621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 414 e-114
AL445650-4|CAH70621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 414 e-114
AL445650-3|CAH70620.1| 1546|Homo sapiens Usher syndrome 2A (auto... 414 e-114
AL358858-2|CAH71588.1| 5202|Homo sapiens Usher syndrome 2A (auto... 414 e-114
AL358858-1|CAH71587.1| 1546|Homo sapiens Usher syndrome 2A (auto... 414 e-114
AL358452-1|CAI19189.1| 5202|Homo sapiens Usher syndrome 2A (auto... 414 e-114
AL139259-1|CAI23041.1| 5202|Homo sapiens Usher syndrome 2A (auto... 414 e-114
AF091889-1|AAF75819.1| 1546|Homo sapiens Usher syndrome type IIa... 414 e-114
AF055580-1|AAC23748.2| 1546|Homo sapiens Usher syndrome type IIa... 413 e-114
AB208887-1|BAD92124.1| 1379|Homo sapiens laminin, gamma 3 precur... 411 e-113
AL583807-2|CAH69983.1| 1587|Homo sapiens laminin, gamma 3 protein. 411 e-113
AL583807-1|CAH69984.2| 1619|Homo sapiens laminin, gamma 3 protein. 411 e-113
AL355872-3|CAI39529.1| 1587|Homo sapiens laminin, gamma 3 protein. 411 e-113
AL355872-2|CAI39530.2| 1619|Homo sapiens laminin, gamma 3 protein. 411 e-113
AF041835-1|AAD36991.1| 1587|Homo sapiens laminin gamma 3 chain p... 399 e-110
BC033663-1|AAH33663.1| 401|Homo sapiens Unknown (protein for IM... 383 e-105
BC113455-1|AAI13456.1| 1786|Homo sapiens laminin, beta 1 protein. 334 3e-90
BC026018-1|AAH26018.2| 1083|Homo sapiens LAMB1 protein protein. 334 3e-90
M61951-1|AAA59486.1| 1786|Homo sapiens laminin B1 protein. 334 5e-90
M61916-1|AAA59482.1| 1786|Homo sapiens laminin B1 protein. 334 5e-90
M55370-1|AAA59485.1| 1786|Homo sapiens laminin B1 protein. 334 5e-90
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 320 8e-86
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 320 8e-86
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 319 1e-85
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 319 1e-85
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 319 1e-85
S77512-1|AAB34682.2| 1798|Homo sapiens laminin beta 2 chain prot... 304 4e-81
Z68155-1|CAA92279.1| 1798|Homo sapiens laminin beta 2 chain prot... 300 5e-80
Z15009-1|CAA78729.1| 1111|Homo sapiens Laminin protein. 293 6e-78
Z15008-1|CAA78728.1| 1193|Homo sapiens Laminin protein. 293 6e-78
X73902-1|CAA52108.1| 1193|Homo sapiens nicein protein. 293 6e-78
U31201-1|AAC50457.1| 1193|Homo sapiens laminin gamma2 chain prot... 293 6e-78
U31200-1|AAC50456.1| 1111|Homo sapiens alternatively spliced lam... 293 6e-78
BC113378-1|AAI13379.1| 1111|Homo sapiens laminin, gamma 2 protein. 293 6e-78
AL354953-2|CAH70980.1| 1193|Homo sapiens laminin, gamma 2 protein. 293 6e-78
BC112286-1|AAI12287.1| 1111|Homo sapiens laminin, gamma 2 protein. 293 8e-78
AF028816-1|AAC95123.1| 1761|Homo sapiens laminin beta-4 chain pr... 290 6e-77
X79683-1|CAA56130.1| 1798|Homo sapiens beta2/S laminin chain pro... 288 3e-76
AK075536-1|BAC11679.1| 529|Homo sapiens protein ( Homo sapiens ... 275 2e-72
S76436-1|AAB21121.2| 507|Homo sapiens heparan sulfate proteogly... 270 6e-71
L25541-1|AAA61834.1| 1170|Homo sapiens laminin S B3 chain protein. 267 4e-70
Z99289-2|CAI42325.1| 1823|Homo sapiens laminin, alpha 4 protein. 263 1e-68
U17760-1|AAC51352.1| 1172|Homo sapiens laminin S B3 chain protein. 263 1e-68
BC075838-1|AAH75838.1| 1172|Homo sapiens laminin, beta 3 protein. 263 1e-68
AY035783-1|AAK61364.1| 1172|Homo sapiens laminin 5 beta 3 subuni... 263 1e-68
AL590106-3|CAI12950.1| 1823|Homo sapiens laminin, alpha 4 protein. 263 1e-68
AL031316-2|CAI20062.1| 1172|Homo sapiens laminin, beta 3 protein. 263 1e-68
AL023754-1|CAI19989.1| 1172|Homo sapiens laminin, beta 3 protein. 263 1e-68
AB210027-1|BAE06109.1| 1852|Homo sapiens LAMA4 variant protein p... 262 1e-68
X91171-1|CAA62596.1| 1816|Homo sapiens laminin alpha 4 protein. 260 9e-68
BC066552-1|AAH66552.1| 1816|Homo sapiens LAMA4 protein protein. 260 9e-68
S78569-1|AAB34635.1| 1816|Homo sapiens laminin alpha 4 chain pro... 258 3e-67
U75586-1|AAD09221.1| 604|Homo sapiens netrin-1 protein. 246 9e-64
D37766-1|BAA22263.1| 1172|Homo sapiens Laminin-5 beta3 chain pro... 245 2e-63
AF172277-3|AAF22284.1| 761|Homo sapiens laminin beta 1 related ... 232 2e-59
BC026237-1|AAH26237.1| 324|Homo sapiens Unknown (protein for IM... 210 9e-53
AB208922-1|BAD92159.1| 1853|Homo sapiens laminin alpha 2 subunit... 206 9e-52
M64283-1|AAA52699.1| 453|Homo sapiens heparan sulfate proteogly... 206 1e-51
X84900-1|CAA59325.1| 1806|Homo sapiens alpha 3B chain of laminin... 204 4e-51
X85108-1|CAA59429.1| 1331|Homo sapiens alpha3b subunit of lamini... 202 2e-50
AF278532-1|AAG30822.1| 628|Homo sapiens beta-netrin protein. 202 3e-50
AF297711-1|AAG53651.1| 628|Homo sapiens netrin 4 precursor prot... 201 4e-50
L34155-1|AAA59483.1| 1713|Homo sapiens epiligrin alpha 3 subunit... 198 2e-49
AY330211-1|AAP92113.1| 605|Homo sapiens netrin 4 protein. 198 2e-49
X85107-1|CAA59428.1| 1238|Homo sapiens alpha3a subunit of lamini... 186 1e-45
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 184 7e-45
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 184 7e-45
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 184 7e-45
X76939-1|CAA54258.1| 1581|Homo sapiens laminin A3 protein. 181 5e-44
U86759-1|AAC51247.1| 580|Homo sapiens netrin-2 like protein pro... 177 6e-43
U86758-1|AAC51246.1| 580|Homo sapiens netrin-2 like protein pro... 177 6e-43
AL353631-1|CAI16126.1| 522|Homo sapiens netrin G2 protein. 177 8e-43
AL159997-4|CAI40855.1| 522|Homo sapiens netrin G2 protein. 177 8e-43
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 176 1e-42
BC045172-1|AAH45172.2| 749|Homo sapiens LAMB4 protein protein. 173 1e-41
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 173 1e-41
AB011105-1|BAA25459.1| 1645|Homo sapiens KIAA0533 protein protein. 172 2e-41
BC013770-1|AAH13770.1| 530|Homo sapiens netrin G2 protein. 171 5e-41
AL353631-2|CAI16125.1| 530|Homo sapiens netrin G2 protein. 171 5e-41
AL159997-3|CAI40856.1| 530|Homo sapiens netrin G2 protein. 171 5e-41
AB058760-1|BAB47486.2| 549|Homo sapiens KIAA1857 protein protein. 171 5e-41
AL590427-6|CAH73381.1| 539|Homo sapiens netrin G1 protein. 169 2e-40
AL513187-3|CAH73830.1| 539|Homo sapiens netrin G1 protein. 169 2e-40
AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein pr... 167 9e-40
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 165 4e-39
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 163 1e-38
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 163 1e-38
AL138836-3|CAC22313.2| 602|Homo sapiens multiple EGF-like-domai... 153 9e-36
BC013591-1|AAH13591.2| 469|Homo sapiens NTN4 protein protein. 151 5e-35
AY327114-1|AAQ72569.1| 1668|Homo sapiens laminin alpha 3 splice ... 148 3e-34
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 146 1e-33
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 146 2e-33
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 146 2e-33
X70904-1|CAA50261.1| 414|Homo sapiens Laminin Ah protein. 144 7e-33
AL590427-5|CAH73382.1| 494|Homo sapiens netrin G1 protein. 140 9e-32
AL513187-4|CAH73831.1| 494|Homo sapiens netrin G1 protein. 140 9e-32
AB011542-1|BAA32470.1| 375|Homo sapiens MEGF9 protein. 137 8e-31
M59832-1|AAA63215.1| 1130|Homo sapiens merosin protein. 132 2e-29
X84392-1|CAA59114.1| 158|Homo sapiens alpha3A protein. 129 2e-28
BC062318-1|AAH62318.1| 559|Homo sapiens LAMA1 protein protein. 124 6e-27
BC039051-1|AAH39051.1| 747|Homo sapiens LAMA1 protein protein. 124 6e-27
AF131842-1|AAD20057.1| 260|Homo sapiens Unknown protein. 124 6e-27
AB208853-1|BAD92090.1| 1408|Homo sapiens Laminin alpha 3b chain ... 124 6e-27
AL590103-9|CAI12132.1| 196|Homo sapiens heparan sulfate proteog... 116 2e-24
AY358365-1|AAQ88731.1| 438|Homo sapiens YLSR571 protein. 115 4e-24
BX538348-1|CAD98143.1| 365|Homo sapiens hypothetical protein pr... 114 5e-24
BC030220-1|AAH30220.1| 438|Homo sapiens netrin G1 protein. 114 5e-24
AL590427-4|CAH73385.1| 480|Homo sapiens netrin G1 protein. 114 5e-24
AL590427-3|CAH73384.1| 460|Homo sapiens netrin G1 protein. 114 5e-24
AL590427-2|CAH73383.1| 438|Homo sapiens netrin G1 protein. 114 5e-24
AL590427-1|CAH73380.1| 364|Homo sapiens netrin G1 protein. 114 5e-24
AL513187-6|CAH73833.1| 460|Homo sapiens netrin G1 protein. 114 5e-24
AL513187-5|CAH73832.1| 438|Homo sapiens netrin G1 protein. 114 5e-24
AL513187-2|CAH73829.1| 480|Homo sapiens netrin G1 protein. 114 5e-24
AL513187-1|CAH73828.1| 364|Homo sapiens netrin G1 protein. 114 5e-24
AB023193-1|BAA76820.2| 386|Homo sapiens KIAA0976 protein protein. 114 5e-24
AY358165-1|AAQ88532.1| 422|Homo sapiens LHLL9381 protein. 114 7e-24
BC033207-1|AAH33207.1| 489|Homo sapiens hypothetical protein BC... 113 2e-23
BC021210-1|AAH21210.2| 350|Homo sapiens LOC126147 protein protein. 113 2e-23
BC018697-1|AAH18697.2| 489|Homo sapiens hypothetical protein BC... 113 2e-23
BC018654-1|AAH18654.2| 489|Homo sapiens hypothetical protein BC... 113 2e-23
AK024691-1|BAB14964.1| 341|Homo sapiens protein ( Homo sapiens ... 110 8e-23
AB052951-1|BAC53753.1| 866|Homo sapiens SRECRP-1 protein. 110 8e-23
Z99289-8|CAI42333.1| 117|Homo sapiens laminin, alpha 4 protein. 109 1e-22
AF522196-1|AAN45861.1| 870|Homo sapiens scavenger receptor type... 109 1e-22
AB024433-1|BAD93345.1| 866|Homo sapiens NSR1 protein. 109 1e-22
D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein. 107 1e-21
D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein. 107 1e-21
BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor clas... 107 1e-21
AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein. 107 1e-21
AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein. 107 1e-21
AB010099-1|BAA31347.1| 94|Homo sapiens laminin alpha 5 chain p... 101 5e-20
BC084578-1|AAH84578.1| 719|Homo sapiens AGRN protein protein. 95 3e-18
AL645608-12|CAI15575.2| 2045|Homo sapiens agrin protein. 95 3e-18
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 95 3e-18
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 95 3e-18
AK098809-1|BAC05419.1| 320|Homo sapiens protein ( Homo sapiens ... 95 4e-18
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 94 7e-18
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 94 7e-18
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 94 7e-18
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro... 94 7e-18
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 94 1e-17
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 94 1e-17
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 94 1e-17
AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein. 93 1e-17
AB052949-1|BAC02695.1| 337|Homo sapiens SREC-4 protein. 93 1e-17
AB052947-1|BAC02693.1| 342|Homo sapiens SREC-2 protein. 93 1e-17
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 92 4e-17
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 92 4e-17
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 91 7e-17
AB011536-1|BAA32464.1| 1364|Homo sapiens MEGF2 protein. 91 7e-17
BC067813-1|AAH67813.1| 248|Homo sapiens LAMC1 protein protein. 91 9e-17
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 90 1e-16
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 90 1e-16
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 90 1e-16
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 90 1e-16
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 90 1e-16
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 90 1e-16
AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein. 89 4e-16
X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 85 3e-15
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 85 3e-15
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 85 3e-15
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 85 3e-15
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 85 3e-15
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 85 3e-15
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 85 3e-15
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 85 3e-15
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 85 3e-15
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 85 3e-15
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 85 3e-15
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 84 1e-14
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 84 1e-14
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 84 1e-14
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 84 1e-14
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 84 1e-14
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 84 1e-14
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 84 1e-14
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 83 1e-14
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 83 2e-14
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 82 4e-14
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 80 1e-13
AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens ... 79 2e-13
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 79 3e-13
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 78 5e-13
AY764265-1|AAW47412.1| 209|Homo sapiens netrin G1 isoform G1m p... 78 5e-13
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 78 5e-13
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 78 5e-13
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 78 5e-13
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 78 5e-13
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 78 5e-13
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 78 5e-13
AY764260-1|AAW47407.1| 167|Homo sapiens netrin G1 isoform G1a p... 78 7e-13
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 78 7e-13
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 78 7e-13
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 77 2e-12
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 77 2e-12
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 77 2e-12
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 77 2e-12
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 77 2e-12
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 77 2e-12
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 77 2e-12
BC009326-1|AAH09326.2| 595|Homo sapiens SCARF2 protein protein. 77 2e-12
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 77 2e-12
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 77 2e-12
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 77 2e-12
AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein. 77 2e-12
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 75 4e-12
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 75 4e-12
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 75 4e-12
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 75 4e-12
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 75 4e-12
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 75 6e-12
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 75 6e-12
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 75 6e-12
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 75 6e-12
AJ316284-1|CAC87720.2| 1392|Homo sapiens neurexin 3-alpha protein. 75 6e-12
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 75 6e-12
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 75 6e-12
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 75 6e-12
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 75 6e-12
AB018286-1|BAA34463.2| 1205|Homo sapiens KIAA0743 protein protein. 75 6e-12
BC131820-1|AAI31821.1| 1976|Homo sapiens FRAS1 protein protein. 74 9e-12
AJ512501-1|CAD54734.1| 4007|Homo sapiens extracellular matrix pr... 74 9e-12
Z99289-7|CAI42332.1| 177|Homo sapiens laminin, alpha 4 protein. 74 1e-11
AK057327-1|BAB71429.1| 721|Homo sapiens protein ( Homo sapiens ... 73 2e-11
AF463518-1|AAL68839.1| 1311|Homo sapiens cell recognition protei... 73 2e-11
AB100094-1|BAC55272.1| 1308|Homo sapiens hypothetical protein pr... 73 2e-11
AB051550-1|BAB21854.2| 1322|Homo sapiens KIAA1763 protein protein. 73 2e-11
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 73 3e-11
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 73 3e-11
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 73 3e-11
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 73 3e-11
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 73 3e-11
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 73 3e-11
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 73 3e-11
M24630-1|AAA52703.1| 1625|Homo sapiens hexabrachion protein. 72 3e-11
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 71 6e-11
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 71 6e-11
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 71 1e-10
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 71 1e-10
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 71 1e-10
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 71 1e-10
Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 70 1e-10
Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 70 1e-10
Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 70 1e-10
AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 70 1e-10
AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 70 1e-10
AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 70 1e-10
AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein. 70 1e-10
BC113373-1|AAI13374.1| 1331|Homo sapiens contactin associated pr... 70 2e-10
BC093780-1|AAH93780.1| 1331|Homo sapiens contactin associated pr... 70 2e-10
AF319045-1|AAK34932.1| 1331|Homo sapiens contactin-associated pr... 70 2e-10
AF193613-1|AAF25199.1| 1331|Homo sapiens cell recognition molecu... 70 2e-10
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 70 2e-10
AB020675-1|BAA74891.1| 1339|Homo sapiens KIAA0868 protein protein. 70 2e-10
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 69 2e-10
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 69 2e-10
AL589653-1|CAI40809.1| 1560|Homo sapiens proprotein convertase s... 69 2e-10
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 69 2e-10
AL391868-1|CAI40675.1| 1560|Homo sapiens proprotein convertase s... 69 2e-10
AL353607-3|CAI41234.1| 1560|Homo sapiens proprotein convertase s... 69 2e-10
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 69 2e-10
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 69 2e-10
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 69 2e-10
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 69 4e-10
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 69 4e-10
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 69 4e-10
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 69 4e-10
AY280362-1|AAP35084.1| 2386|Homo sapiens EGF domain-containing p... 69 4e-10
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 69 4e-10
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 69 4e-10
AB011541-1|BAA32469.2| 2785|Homo sapiens MEGF8 protein. 69 4e-10
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 67 1e-09
AB052957-1|BAC15607.1| 803|Homo sapiens soluble form FELE-1 pro... 67 1e-09
L34156-1|AAA59484.1| 145|Homo sapiens epiligrin alpha 3 subunit... 66 2e-09
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 66 2e-09
AB011150-1|BAA25504.2| 1542|Homo sapiens KIAA0578 protein protein. 66 2e-09
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 65 4e-09
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 65 4e-09
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 65 4e-09
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 65 4e-09
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 64 7e-09
BC101705-1|AAI01706.1| 1272|Homo sapiens attractin protein. 64 7e-09
AL353193-3|CAH70472.1| 1429|Homo sapiens attractin protein. 64 7e-09
AL353193-2|CAH70471.1| 1272|Homo sapiens attractin protein. 64 7e-09
AL132773-2|CAI22616.1| 1429|Homo sapiens attractin protein. 64 7e-09
AL132773-1|CAI22614.1| 1272|Homo sapiens attractin protein. 64 7e-09
AL109805-3|CAI21878.1| 1429|Homo sapiens attractin protein. 64 7e-09
AL109805-2|CAI21876.1| 1272|Homo sapiens attractin protein. 64 7e-09
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 64 7e-09
AF218915-1|AAF72881.1| 1429|Homo sapiens membrane attractin prec... 64 7e-09
AF218910-1|AAF72882.1| 1272|Homo sapiens secreted attractin prec... 64 7e-09
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 64 7e-09
AF106861-1|AAD03057.1| 1272|Homo sapiens attractin-2 protein. 64 7e-09
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 64 7e-09
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 64 7e-09
AB011120-1|BAA25474.1| 452|Homo sapiens KIAA0548 protein protein. 64 7e-09
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 64 9e-09
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 64 9e-09
AB077881-1|BAB83897.1| 1306|Homo sapiens caspr5 protein. 64 9e-09
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 64 1e-08
AY442317-1|AAR14297.1| 1379|Homo sapiens attractin-like protein ... 64 1e-08
AL512304-1|CAH74015.2| 1379|Homo sapiens attractin-like 1 protein. 64 1e-08
AL392087-1|CAI40794.2| 1379|Homo sapiens attractin-like 1 protein. 64 1e-08
AL357059-1|CAH70625.2| 1379|Homo sapiens attractin-like 1 protein. 64 1e-08
AL356100-1|CAI40417.2| 1379|Homo sapiens attractin-like 1 protein. 64 1e-08
AL355530-1|CAI13483.2| 1379|Homo sapiens attractin-like 1 protein. 64 1e-08
AK127277-1|BAC86914.1| 1233|Homo sapiens protein ( Homo sapiens ... 64 1e-08
AB011106-1|BAA25460.2| 1028|Homo sapiens KIAA0534 protein protein. 64 1e-08
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 63 2e-08
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 63 2e-08
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 63 2e-08
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 63 2e-08
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 63 2e-08
AK056528-1|BAB71205.1| 963|Homo sapiens protein ( Homo sapiens ... 63 2e-08
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 63 2e-08
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 63 2e-08
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 63 2e-08
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 63 2e-08
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 63 2e-08
BC064487-1|AAH64487.1| 651|Homo sapiens FRAS1 protein protein. 62 3e-08
BC052281-1|AAH52281.1| 651|Homo sapiens FRAS1 protein protein. 62 3e-08
AY764267-1|AAW47414.1| 153|Homo sapiens netrin G1 isoform G1o p... 62 5e-08
Z95636-1|CAB09137.1| 953|Homo sapiens laminin alpha 5 chain pro... 61 6e-08
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 61 8e-08
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 60 1e-07
AY781194-1|AAW47415.1| 111|Homo sapiens netrin G1 isoform G1b p... 60 1e-07
AY764266-1|AAW47413.1| 133|Homo sapiens netrin G1 isoform G1n p... 60 1e-07
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 60 1e-07
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 60 2e-07
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 60 2e-07
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 59 3e-07
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 59 3e-07
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 59 3e-07
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 59 3e-07
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 59 3e-07
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 59 3e-07
BC036788-1|AAH36788.2| 494|Homo sapiens integrin, beta-like 1 (... 59 3e-07
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 59 3e-07
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 59 3e-07
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 59 3e-07
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 59 3e-07
AL355807-1|CAI14550.1| 494|Homo sapiens integrin, beta-like 1 (... 59 3e-07
AL160153-1|CAH73400.1| 494|Homo sapiens integrin, beta-like 1 (... 59 3e-07
AL139800-1|CAH71455.1| 494|Homo sapiens integrin, beta-like 1 (... 59 3e-07
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 59 3e-07
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 59 3e-07
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 59 3e-07
AK097549-1|BAC05096.1| 775|Homo sapiens protein ( Homo sapiens ... 59 3e-07
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 59 3e-07
AF072752-1|AAD17666.1| 494|Homo sapiens ten integrin EGF-like r... 59 3e-07
AE014302-1|AAN16024.1| 494|Homo sapiens ITGBL1 protein. 59 3e-07
BC105690-1|AAI05691.1| 195|Homo sapiens Unknown (protein for MG... 58 6e-07
AY358370-1|AAQ88736.1| 258|Homo sapiens EGFL5 protein. 58 6e-07
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 58 6e-07
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 57 1e-06
AB035356-1|BAA87821.1| 1477|Homo sapiens neurexin I-alpha protei... 57 1e-06
Z94057-1|CAI21650.1| 1358|Homo sapiens tenascin R (restrictin, j... 57 1e-06
Z94055-1|CAI19943.1| 1358|Homo sapiens tenascin R (restrictin, j... 57 1e-06
Z67996-1|CAA91947.1| 1358|Homo sapiens tenascin-R (restrictin) p... 57 1e-06
X98085-1|CAA66709.1| 1358|Homo sapiens tenascin-R protein. 57 1e-06
BC129830-1|AAI29831.1| 1257|Homo sapiens TNR protein protein. 57 1e-06
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 57 1e-06
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 57 1e-06
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 57 1e-06
BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein. 56 2e-06
BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin t... 56 2e-06
BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1... 56 2e-06
AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein. 56 2e-06
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 56 2e-06
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 56 2e-06
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 56 2e-06
AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1... 56 2e-06
AC007462-1|AAF03536.1| 681|Homo sapiens unknown protein. 56 2e-06
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 56 2e-06
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 56 2e-06
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 56 2e-06
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 56 2e-06
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 56 2e-06
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 56 2e-06
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 56 2e-06
AB177862-1|BAD66840.1| 1434|Homo sapiens KIAA0921 splice variant... 56 2e-06
AB023138-1|BAA76765.2| 1658|Homo sapiens KIAA0921 protein protein. 56 2e-06
BC131613-1|AAI31614.1| 292|Homo sapiens keratin associated prot... 56 3e-06
X07979-1|CAA30790.1| 798|Homo sapiens protein ( Human mRNA for ... 55 6e-06
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 55 6e-06
DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 55 6e-06
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 55 6e-06
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 55 6e-06
BX537407-1|CAD97649.1| 823|Homo sapiens hypothetical protein pr... 55 6e-06
BC020057-1|AAH20057.1| 798|Homo sapiens integrin, beta 1 (fibro... 55 6e-06
AY205235-1|AAO47606.1| 673|Homo sapiens URG11 protein. 55 6e-06
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 55 6e-06
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 55 6e-06
AL365203-2|CAI14426.1| 798|Homo sapiens integrin, beta 1 (fibro... 55 6e-06
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 55 6e-06
AC026888-1|AAF87841.1| 328|Homo sapiens NRXNIII protein. 55 6e-06
AC011440-1|AAF61277.1| 288|Homo sapiens NRXN3 protein. 55 6e-06
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 54 7e-06
AB126070-1|BAD20197.1| 278|Homo sapiens keratin associated prot... 54 7e-06
M35198-1|AAA36122.2| 788|Homo sapiens integrin beta-subunit pro... 54 1e-05
BC121178-1|AAI21179.1| 788|Homo sapiens integrin, beta 6 protein. 54 1e-05
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 54 1e-05
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 54 1e-05
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 54 1e-05
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 54 1e-05
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 54 1e-05
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 54 1e-05
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 54 1e-05
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 54 1e-05
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 54 1e-05
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 54 1e-05
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 54 1e-05
AC080166-2|AAY24053.1| 449|Homo sapiens unknown protein. 54 1e-05
AC044790-1|AAK68154.1| 1712|Homo sapiens NRXN2 protein. 54 1e-05
AC008045-1|AAF28465.1| 154|Homo sapiens neurexin III protein. 54 1e-05
AC004891-1|AAC36298.1| 208|Homo sapiens unknown protein. 54 1e-05
AB035266-1|BAA94075.1| 1712|Homo sapiens neurexin II protein. 54 1e-05
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 54 1e-05
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 54 1e-05
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 54 1e-05
S80335-1|AAB21332.1| 798|Homo sapiens integrin beta 7 subunit p... 54 1e-05
S49378-1|AAB23688.1| 798|Homo sapiens integrin beta 7 subunit p... 54 1e-05
M68892-1|AAA59184.1| 798|Homo sapiens integrin beta-7 subunit p... 54 1e-05
M62880-1|AAA59185.1| 798|Homo sapiens integrin beta-7 subunit p... 54 1e-05
L23823-1|AAA36118.1| 798|Homo sapiens integrin beta 7 subunit p... 54 1e-05
BC015916-1|AAH15916.1| 798|Homo sapiens ITGB7 protein protein. 54 1e-05
AK027833-1|BAB55399.1| 441|Homo sapiens protein ( Homo sapiens ... 54 1e-05
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 53 2e-05
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 53 2e-05
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 53 2e-05
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 53 2e-05
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 53 2e-05
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 53 2e-05
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 53 2e-05
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 53 2e-05
AK092479-1|BAC03900.1| 463|Homo sapiens protein ( Homo sapiens ... 53 2e-05
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 53 2e-05
AB008375-1|BAA22994.1| 403|Homo sapiens osteoblast specific cys... 53 2e-05
U95204-1|AAB71380.1| 784|Homo sapiens platelet membrane glycopr... 53 2e-05
M57494-1|AAA52600.1| 761|Homo sapiens platelet glycoprotein III... 53 2e-05
M35999-1|AAA35927.1| 788|Homo sapiens protein ( Human platelet ... 53 2e-05
M32686-1|AAA67537.1| 762|Homo sapiens glycoprotein IIIa protein. 53 2e-05
M20311-1|AAA60122.1| 788|Homo sapiens glycoprotein IIIa protein. 53 2e-05
J02703-1|AAA52589.1| 788|Homo sapiens ITGB3 protein. 53 2e-05
CR788268-5|CAI95050.1| 1288|Homo sapiens contactin associated pr... 53 2e-05
CR788268-4|CAI95048.1| 746|Homo sapiens contactin associated pr... 53 2e-05
CR788268-2|CAI95046.1| 1175|Homo sapiens contactin associated pr... 53 2e-05
BX664735-4|CAI16326.1| 1288|Homo sapiens contactin associated pr... 53 2e-05
BX664735-3|CAI95321.1| 746|Homo sapiens contactin associated pr... 53 2e-05
BX664735-1|CAI16324.1| 1175|Homo sapiens contactin associated pr... 53 2e-05
BX649569-4|CAI12628.1| 1288|Homo sapiens contactin associated pr... 53 2e-05
BX649569-3|CAI94998.1| 746|Homo sapiens contactin associated pr... 53 2e-05
BX649569-1|CAI12626.1| 1175|Homo sapiens contactin associated pr... 53 2e-05
BC127667-1|AAI27668.1| 788|Homo sapiens integrin, beta 3 (plate... 53 2e-05
BC127666-1|AAI27667.1| 788|Homo sapiens integrin, beta 3 (plate... 53 2e-05
AJ968414-1|CAI91316.1| 284|Homo sapiens Cysteine-rich with EGF-... 53 2e-05
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 53 2e-05
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 53 2e-05
AB032953-1|BAA86441.2| 2144|Homo sapiens KIAA1127 protein protein. 53 2e-05
Y00057-1|CAA68266.1| 761|Homo sapiens protein ( Human mRNA for ... 52 3e-05
X64072-1|CAA45427.1| 769|Homo sapiens integrin beta-2 subunit p... 52 3e-05
M15395-1|AAA59490.1| 769|Homo sapiens LYAM1 protein. 52 3e-05
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 52 3e-05
DQ470677-1|ABF06669.1| 325|Homo sapiens CRELD2-gamma protein. 52 3e-05
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 52 3e-05
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 52 3e-05
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 52 3e-05
BC021077-1|AAH21077.1| 758|Homo sapiens ITGB2 protein protein. 52 3e-05
BC005861-1|AAH05861.1| 769|Homo sapiens ITGB2 protein protein. 52 3e-05
AL163300-3|CAB90553.1| 769|Homo sapiens cell surface adhesion g... 52 3e-05
AK222505-1|BAD96225.1| 769|Homo sapiens integrin beta chain, be... 52 3e-05
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 52 3e-05
AB100093-1|BAC55271.1| 1235|Homo sapiens hypothetical protein pr... 52 3e-05
AB100092-1|BAC55270.1| 1260|Homo sapiens hypothetical protein pr... 52 3e-05
AF283412-1|AAL38110.1| 172|Homo sapiens candidate tumor suppres... 52 4e-05
>AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain
precursor protein.
Length = 3695
Score = 1702 bits (4220), Expect = 0.0
Identities = 989/3000 (32%), Positives = 1464/3000 (48%), Gaps = 218/3000 (7%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CDIC A N K HP A+D WWQSPPLSRG++YNEVN+T+DLGQ FHVAYV +K
Sbjct: 103 CDICTAANSNKAHPASNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFA 162
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G+T++PWQ+F+ S +DC FG ++L+ IT+DD+ IC+TEYS+I
Sbjct: 163 NSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRI 222
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GEI +SL+N RP + + S +L+E+T+ATNVRLR LRT LLGHLM A +DPT
Sbjct: 223 VPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT 282
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGGRC+C+GHAD C+ DP L C CQHNTCG C++CC GF
Sbjct: 283 VTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFR-LQCTCQHNTCGGTCDRCCPGFN 341
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q+ W+ + C+ CNC+ H T+C YDPE+D +R S ++G Y+GGG C++CQH+T
Sbjct: 342 QQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTA 401
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C P +YR D VC+ C C+ F+ G CE+ +GRC CRP F C C
Sbjct: 402 GVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVC 461
Query: 394 AYGYFDYPNCKP--------------------CTCNLNGTEGEHCT--PTDGLCPCKYNY 431
A G+ +P+C P C C+ GT+G C P G C CK N+
Sbjct: 462 AEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNF 521
Query: 432 AGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
G CE+C G+Y P C+ C+C++ G CD TG C C+ + G TC++C GY+++
Sbjct: 522 QGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF 581
Query: 492 PTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
P C+ C C +GT P CD+ +G+C+C+ F GP CD+C GY+ C C CD
Sbjct: 582 PLCQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDRCRPGYH-----GFPNCQACTCD 635
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGL 610
P G+ C A G C C + G C +CSPG++ +P C+ C+C GS+ + CD +G
Sbjct: 636 PRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQ 695
Query: 611 CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGEL-CQCKDRVQG 669
C C+ G +CDTC YN+P CE +C P G+ ++P ++ C C+ V+G
Sbjct: 696 CSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDP---ALPEAQVPCMCRAHVEG 752
Query: 670 RICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL 729
C+ CKP +W L NP GC +C+C+L GTL + C +GQC CK HV + C C
Sbjct: 753 PSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCK 812
Query: 730 DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLH 789
DGF+ L D FGC C CDIGG++ +C+ TG C C +G C +P R HY P LH
Sbjct: 813 DGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLH 872
Query: 790 QFQYEVEDGVTQSG-PVRYRNSEEVFPEYSWKGYVVFSLLQNEVINIIQITKSSLYRMVL 848
+ E+E+ T G VR+ + F +SW+GY + +Q ++ + +T L+ +V
Sbjct: 873 HLRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAQMAPVQPRIVARLNLTSPDLFWLVF 932
Query: 849 KYANPLRDPVVANIVITPES-----VVDIQQKFNVYLRPTVLPQLVTVAGDKGVTPAPFV 903
+Y N V + + E Q V P+ P +TV +G PFV
Sbjct: 933 RYVNRGAMSVSGRVSVREEGRSAACANCTAQSQPVAFPPSTEPAFITVP-QRGFGE-PFV 990
Query: 904 MNPGNWTVTIKTNKEIMIDYFVLIPEAYYEATILTKMVDKPCIV-------GDKKLCRQF 956
+NPG W + ++ + +++DY VL+P AYYEA +L V + C GD C +
Sbjct: 991 LNPGTWALRVEA-EGVLLDYVVLLPSAYYEAALLQLRVTEACTYRPSAQQSGDN--CLLY 1047
Query: 957 AYPSLSGKSTADVTSLVTSVDSFIDDPVQLSELKVEPNTIPILRTT-----LQYNMRIEK 1011
+ L G +A + D+ + P +L P+ P++ T +Q + + +
Sbjct: 1048 THLPLDGFPSAAGLEALCRQDNSLPRPCPTEQLS--PSHPPLITCTGSDVDVQLQVAVPQ 1105
Query: 1012 PGQYVLLVEYVTPAARNQDLNTGNSTYSSVVKTPVTIKFQSGPDDQHLVETDGIINFNDC 1071
PG+Y L+VEY AR + V TP Q P G+++ + C
Sbjct: 1106 PGRYALVVEYANEDARQE--------VGVAVHTP-----QRAPQQ-------GLLSLHPC 1145
Query: 1072 PYTAPCRQVMVDDYSRIQFVTVTDPNNVVFLLDQPDTEAAIKSVVAIPQAEWHLDYLTPR 1131
Y+ CR D + + +V +Q + V +P E+ +++ PR
Sbjct: 1146 LYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQ--ARFFLHGVTLVPIEEFSPEFVEPR 1203
Query: 1132 PYCLRRNGR-------CDPAVF----NAVV--DAKKVEFESGT--------------GGD 1164
C+ +G C P+ F ++ D + + G G
Sbjct: 1204 VSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPATSPAGP 1263
Query: 1165 RETRPQILNNSTTVVYLPTQSEPVILEGKVSAPGEYLFMVHYYQPDHPESTMEVTVNTDG 1224
R P ++ L V+ V G Y F++H YQP HP +EV +N G
Sbjct: 1264 RPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLINA-G 1322
Query: 1225 QKQETNLPIQHCPSNSGCRALLRKPDTSTSFLVNENFTLVFKGNTSKGVWLDYVLVIEAS 1284
+ + + CP GCR L+ + + + T+ + + +WLDYVLV+ +
Sbjct: 1323 RVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPEGRWLWLDYVLVVPEN 1382
Query: 1285 DFTDAVLTEANILDYTREFIEQCASYNYYISPNETGL-CREAMFSITSEYNSGARPCLCD 1343
++ L E LD + +FI CA+ Y+ISP+ + L CR A S++ YN+GARPC C
Sbjct: 1383 VYSFGYLREEP-LDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCH 1441
Query: 1344 FMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD-NGMCIC 1402
+G+T C FGGQCPC +VIGR CS C TGY+GFPNCRPC C +CD+ G CIC
Sbjct: 1442 EVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDC-GARLCDELTGQCIC 1500
Query: 1403 PKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG-NQLQCEADSGKCACRENVRGRV 1461
P +C C+P TF GC++CNC+ G+ C+ DSG+C CR NV GR
Sbjct: 1501 PPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRR 1560
Query: 1462 CDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDD 1521
CD C PG + +P C C C+ GT VCD T QCYCK NV+G CD C F+L
Sbjct: 1561 CDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAA 1620
Query: 1522 NPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELTNVTV 1581
NP GCT+CFCFG T RC SS YT +M W VL++ ++ PHE P +
Sbjct: 1621 NPKGCTRCFCFGATERCRSSSYTRQEFVDMEGW----VLLSTDRQVVPHERQPGTEMLRA 1676
Query: 1582 LTVGLNDGVTNG-KVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT-RGDG--DAVAAPDVI 1637
+ + V Y+ AP YLG R++SYGG L Y +H T RGD + PDV+
Sbjct: 1677 DLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVV 1736
Query: 1638 IAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFS-TLDGAPVTRDQFMHALVNISGLYIR 1696
+ G + P G ++L E F T V+R++ M L ++ L IR
Sbjct: 1737 LQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIR 1796
Query: 1697 ASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR 1756
A + + S SL V LE+ G A++VE C CP +YRG SC++CA G YR
Sbjct: 1797 ALFSQISSAVSLRRVALEVASPAGQG-----ALASNVELCLCPASYRGDSCQECAPGFYR 1851
Query: 1757 ----LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDC 1812
L G CVPCQC+GHSD+C +G+C++C NT G HCE C +G+ C
Sbjct: 1852 DVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFMSSRD-DPSAPC 1910
Query: 1813 LICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGD 1872
+ C CP+ PSNNFA C L G C C+PGY GA CE CA G++G P L G
Sbjct: 1911 VSCPCPLSVPSNNFAEGCVL--RGGRTQCLCKPGYAGASCERCAPGFFGNP----LVLGS 1964
Query: 1873 YCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACI 1931
C+PC+CSGN +P S CD + G C C+ +T G C +CAPGFYG+A+ NCT C
Sbjct: 1965 SCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCD 2024
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
C G CD +G C+C+ GV G +CDRC H+G N GC PC CG A+E ++C
Sbjct: 2025 CTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFNGCGGCRPCACGPAAEGSECHPQ 2084
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIG 2050
+GQC C G G QC +CA G+W + GC C C G C+ TG+C C PG+ G
Sbjct: 2085 SGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGG-----RCDPHTGRCNCPPGLSG 2139
Query: 2051 EKCDRCPERWVLIPQEG--------CLECDSCTDALIFSVEDLSALLA---NETMDFKDK 2099
E+CD C ++ +P G C CD C L+ +E ALL +
Sbjct: 2140 ERCDTCSQQH-QVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINAS 2198
Query: 2100 ADSFFTTQRLN--YISNQTELLRPKVAQLKTVDIGEVTSSIKT-LETSAKNLLRSAEFAA 2156
+ ++ RLN Q++L P + +T EV T L A+ L A
Sbjct: 2199 SMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTR 2258
Query: 2157 TDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPKVDS---AL 2213
+ + ++ A+ LAA+R R +E++ L GL + P + L
Sbjct: 2259 DQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHL--GLANASAPSGEQLLRTL 2316
Query: 2214 TEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFES 2273
E ++ ++ +DL + AEA + R+ + + E+ +A + + +
Sbjct: 2317 AEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQ 2376
Query: 2274 LVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKLNTAAMGD 2331
+L++ L+ ++ T A+ELN++N RL + + +++ N A +
Sbjct: 2377 HEAGLMDLREALNRAVDAT-------REAQELNSRNQERLEEALQRKQELSRDN-ATLQA 2428
Query: 2332 LIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEA 2391
+ AA D + + + L A
Sbjct: 2429 TLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAA 2488
Query: 2392 THHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXN 2451
HA L + A +L + N + TQ Q + +
Sbjct: 2489 EAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADH 2548
Query: 2452 VTKLNRILDERVRPARERSSSLLADATKAQHAV---DQKLLPNLTATEEVLRKIRDHLSR 2508
T + V +R+ LLA++T + A+ Q+L A + ++RD ++
Sbjct: 2549 -TWATVVRQGLV----DRAQQLLANSTALEEAMLQEQQRLGLVWAALQGARTQLRDVRAK 2603
Query: 2509 ADDDDNAIQXXXXXXXXXXXXXXXN--KADRVNATI-GTTFSVMSHLGPELATSKDWAQT 2565
D + IQ A V A T V S L + W
Sbjct: 2604 KDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQ 2663
Query: 2566 LPKLADEGQKMTSNVESHLKNINDMEPQISSSYHTVK-MXXXXXXXXXXXXXXKLQKLKD 2624
L GQ + V +++ +E + + + + ++++
Sbjct: 2664 YEGL--RGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLALSASIGRVRE 2721
Query: 2625 LVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFRTKE-------KDGF 2677
L+ QAR A++++V + F+ S +Q R P + +++ T + Y + E +D F
Sbjct: 2722 LIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPGQGTEDRF 2781
Query: 2678 ILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRW 2737
++Y+G+ R + DYM + +++ + V +G++ PA +SID+ + + ++
Sbjct: 2782 VMYMGS-------RQATGDYMGVSLRDKKVHWVYQLGEAG-----PAVLSIDEDIGE-QF 2828
Query: 2738 YQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-A 2796
V +DR + +S+ +T + PG + NL + YVGG PS
Sbjct: 2829 AAVSLDRTLQFGHMSVTVERQMIQET--KGDTVAPGAEGLLNLRPDDFVFYVGGYPSTFT 2886
Query: 2797 KLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSG----PQEYRF 2852
+ FP + G IE + + V L+NF +L A R S +G
Sbjct: 2887 PPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGSYL 2946
Query: 2853 DGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLG 2912
DG G+A ++ ++ + + R + +G+++ + + F L +Q+G + L G
Sbjct: 2947 DGTGFARISFDSQIS-TTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLYDFG 3005
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 18/218 (8%)
Query: 3456 FMGCLKGLLMNGQQVTRIGNAVNALRCV-DNIEDGVYFEASNNTHSNYLKLLENFKVGDE 3514
F GC+K L ++G+ + C+ +E G++F S + L +
Sbjct: 3487 FSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGV----ITLDLPGATLPD 3542
Query: 3515 VSISMEVRPRNTTGLLLSVHGKKD--YMVLELLDSEVVANVENGNGPFRATYKLSNKHYL 3572
V + +EVRP TGL+ + + Y+ L++ + +V+ ++G G F + ++ L
Sbjct: 3543 VGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTS--VTRPSVL 3600
Query: 3573 CDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAY--TSTDTHSALYIGGHERPIHKVRGVH 3630
CDG WH++ D S +G + + LY+GG P+ V+
Sbjct: 3601 CDGQWHRLAVMKSGNVLRLEVDAQ-SNHTVGPLLAAAAGAPAPLYLGGLPEPM-AVQPWP 3658
Query: 3631 SRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGV--CP 3666
+ GC+R + V +PV + S GA VG CP
Sbjct: 3659 P--AYCGCMRRLAVNRSPVAMTRSVEVHGA-VGASGCP 3693
Score = 40.7 bits (91), Expect = 0.097
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 15/178 (8%)
Query: 3488 DGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLL---SVHGKKDYMVLEL 3544
D F S ++H ++ +L + + S+SM V PR++ GLLL + + L L
Sbjct: 3339 DSYQFGGSLSSHLEFVGILARHR--NWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFL 3396
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDG--HFSKPGI 3602
+ VA +E RA + ++ G WHK+ DG +S+ G
Sbjct: 3397 SNGHFVAQMEGLGTRLRAQSRQRSR----PGRWHKVSVRWEKNRILLVTDGARAWSQEGP 3452
Query: 3603 GAYTSTDTH---SALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVG 3657
H L++GG H + + GF+GCV+ + + P+ P G
Sbjct: 3453 HRQHQGAEHPQPHTLFVGGLPASSHSSK-LPVTVGFSGCVKRLRLHGRPLGAPTRMAG 3509
>AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein.
Length = 3690
Score = 1697 bits (4208), Expect = 0.0
Identities = 987/3000 (32%), Positives = 1463/3000 (48%), Gaps = 218/3000 (7%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CDIC A N K HP A+D WWQSPPLSRG++YNEVN+T+DLGQ FHVAYV +K
Sbjct: 103 CDICTAANSNKAHPASNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFA 162
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G+T++PWQ+F+ S +DC FG ++L+ IT+DD+ IC+TEYS+I
Sbjct: 163 NSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRI 222
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GEI +SL+N RP + + S +L+E+T+ATNVRLR LRT LLGHLM A +DPT
Sbjct: 223 VPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT 282
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGGRC+C+GHAD C+ DP L C CQHNTCG C++CC GF
Sbjct: 283 VTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFR-LQCTCQHNTCGGTCDRCCPGFN 341
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q+ W+ + C+ CNC+ H T+C YDPE+D +R S ++G Y+GGG C++CQH+T
Sbjct: 342 QQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTT 401
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C P +YR D VC+ C C+ F+ G CE+ +GRC CRP F C C
Sbjct: 402 GVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVC 461
Query: 394 AYGYFDYPNCKP--------------------CTCNLNGTEGEHCT--PTDGLCPCKYNY 431
A G+ +P+C P C C+ GT+G C P G C CK N+
Sbjct: 462 AEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNF 521
Query: 432 AGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
G CE+C G+Y P C+ C+C++ G CD TG C C+ + G TC++C GY+++
Sbjct: 522 QGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF 581
Query: 492 PTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
P C+ C C +GT P CD+ +G+C+C+ F GP CD+C GY+ C C CD
Sbjct: 582 PLCQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDRCRPGYH-----GFPNCQACTCD 635
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGL 610
P G+ C A G C C + G C +CSPG++ +P C+ C+C GS+ + CD +G
Sbjct: 636 PRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQ 695
Query: 611 CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGEL-CQCKDRVQG 669
C C+ G +CDTC YN+P CE +C P G+ ++P ++ C C+ V+G
Sbjct: 696 CSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDP---ALPEAQVPCMCRAHVEG 752
Query: 670 RICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL 729
C+ CKP +W L NP GC +C+C+L GTL + C +GQC CK HV + C C
Sbjct: 753 PSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCK 812
Query: 730 DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLH 789
DGF+ L D FGC C CDIGG++ +C+ TG C C +G C +P R HY P LH
Sbjct: 813 DGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLH 872
Query: 790 QFQYEVEDGVTQSG-PVRYRNSEEVFPEYSWKGYVVFSLLQNEVINIIQITKSSLYRMVL 848
+ E+E+ T G VR+ + F +SW+GY + +Q ++ + +T L+ +V
Sbjct: 873 HLRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAQMAPVQPRIVARLNLTSPDLFWLVF 932
Query: 849 KYANPLRDPVVANIVITPES-----VVDIQQKFNVYLRPTVLPQLVTVAGDKGVTPAPFV 903
+Y N V + + E Q V P+ P +TV +G PFV
Sbjct: 933 RYVNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAFPPSTEPAFITVP-QRGFGE-PFV 990
Query: 904 MNPGNWTVTIKTNKEIMIDYFVLIPEAYYEATILTKMVDKPCIV-------GDKKLCRQF 956
+NPG W + ++ + +++DY VL+P AYYEA +L V + C GD C +
Sbjct: 991 LNPGTWALRVEA-EGVLLDYVVLLPSAYYEAALLQLRVTEACTYRPSAQQSGDN--CLLY 1047
Query: 957 AYPSLSGKSTADVTSLVTSVDSFIDDPVQLSELKVEPNTIPILRTT-----LQYNMRIEK 1011
+ L G +A + D+ + P +L P+ P++ T +Q + + +
Sbjct: 1048 THLPLDGFPSAAGLEALCRQDNSLPRPCPTEQLS--PSHPPLITCTGSDVDVQLQVAVPQ 1105
Query: 1012 PGQYVLLVEYVTPAARNQDLNTGNSTYSSVVKTPVTIKFQSGPDDQHLVETDGIINFNDC 1071
PG+Y L+VEY AR + V TP Q P G+++ + C
Sbjct: 1106 PGRYALVVEYANEDARQE--------VGVAVHTP-----QRAPQQ-------GLLSLHPC 1145
Query: 1072 PYTAPCRQVMVDDYSRIQFVTVTDPNNVVFLLDQPDTEAAIKSVVAIPQAEWHLDYLTPR 1131
Y+ CR D + + +V +Q + V +P E+ +++ PR
Sbjct: 1146 LYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQ--ARFFLHGVTLVPIEEFSPEFVEPR 1203
Query: 1132 PYCLRRNGR-------CDPAVF----NAVV--DAKKVEFESGT--------------GGD 1164
C+ +G C P+ F ++ D + + G G
Sbjct: 1204 VSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSPAGP 1263
Query: 1165 RETRPQILNNSTTVVYLPTQSEPVILEGKVSAPGEYLFMVHYYQPDHPESTMEVTVNTDG 1224
R P ++ L V+ V G Y F++H YQP HP +EV +N G
Sbjct: 1264 RPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLINA-G 1322
Query: 1225 QKQETNLPIQHCPSNSGCRALLRKPDTSTSFLVNENFTLVFKGNTSKGVWLDYVLVIEAS 1284
+ + + CP GCR L+ + + + T+ + + +WLDYVLV+ +
Sbjct: 1323 RVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVPEN 1382
Query: 1285 DFTDAVLTEANILDYTREFIEQCASYNYYISPNETGL-CREAMFSITSEYNSGARPCLCD 1343
++ L E LD + +FI CA+ Y+ISP+ + L CR A S++ YN+GARPC C
Sbjct: 1383 VYSFGYLREEP-LDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCH 1441
Query: 1344 FMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD-NGMCIC 1402
+G+T C FGGQCPC +VIGR CS C TGY+GFPNCRPC C +CD+ G CIC
Sbjct: 1442 EVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDC-GARLCDELTGQCIC 1500
Query: 1403 PKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG-NQLQCEADSGKCACRENVRGRV 1461
P +C C+P TF GC++CNC+ G+ C+ DSG+C CR NV GR
Sbjct: 1501 PPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRR 1560
Query: 1462 CDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDD 1521
CD C PG + +P C C C+ GT VCD T QCYCK NV+G CD C F+L
Sbjct: 1561 CDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAA 1620
Query: 1522 NPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELTNVTV 1581
NP GCT+CFCFG T RC SS YT +M W VL++ ++ PHE P +
Sbjct: 1621 NPKGCTRCFCFGATERCRSSSYTRQEFVDMEGW----VLLSTDRQVVPHERQPGTEMLRA 1676
Query: 1582 LTVGLNDGVTNG-KVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT-RGDG--DAVAAPDVI 1637
+ + V Y+ AP YLG R++SYGG L Y +H T RGD + PDV+
Sbjct: 1677 DLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVV 1736
Query: 1638 IAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFS-TLDGAPVTRDQFMHALVNISGLYIR 1696
+ G + P G ++L E F T V+R++ M L ++ L IR
Sbjct: 1737 LQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIR 1796
Query: 1697 ASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR 1756
A + + S L V LE+ G A++VE C CP +YRG SC++CA G YR
Sbjct: 1797 ALFSQISSAVFLRRVALEVASPAGQG-----ALASNVELCLCPASYRGDSCQECAPGFYR 1851
Query: 1757 ----LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDC 1812
L G CVPCQC+GHSD+C +G+C++C NT G HCE C +G+ C
Sbjct: 1852 DVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRD-DPSAPC 1910
Query: 1813 LICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGD 1872
+ C CP+ PSNNFA C L G C C+PGY GA CE CA G++G P L G
Sbjct: 1911 VSCPCPLSVPSNNFAEGCVL--RGGRTQCLCKPGYAGASCERCAPGFFGNP----LVLGS 1964
Query: 1873 YCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACI 1931
C+PC+CSGN +P S CD + G C C+ +T G C +CAPGFYG+A+ NCT C
Sbjct: 1965 SCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCD 2024
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
C G CD +G C+C+ GV G +CDRC H+G + GC PC CG A+E ++C
Sbjct: 2025 CTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQ 2084
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIG 2050
+GQC C G G QC +CA G+W + GC C C G C+ TG+C C PG+ G
Sbjct: 2085 SGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGG-----RCDPHTGRCNCPPGLSG 2139
Query: 2051 EKCDRCPERWVLIPQEG--------CLECDSCTDALIFSVEDLSALLA---NETMDFKDK 2099
E+CD C ++ +P G C CD C L+ +E ALL +
Sbjct: 2140 ERCDTCSQQH-QVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINAS 2198
Query: 2100 ADSFFTTQRLN--YISNQTELLRPKVAQLKTVDIGEVTSSIKT-LETSAKNLLRSAEFAA 2156
+ ++ RLN Q++L P + +T EV T L A+ L A
Sbjct: 2199 SMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTR 2258
Query: 2157 TDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPKVDS---AL 2213
+ + ++ A+ LAA+R R +E++ L GL + P + L
Sbjct: 2259 DQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHL--GLANASAPSGEQLLRTL 2316
Query: 2214 TEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFES 2273
E ++ ++ +DL + AEA + R+ + + E+ +A + + +
Sbjct: 2317 AEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQ 2376
Query: 2274 LVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKLNTAAMGD 2331
+L++ L+ ++ T A+ELN++N RL + + +++ N A +
Sbjct: 2377 HEAGLMDLREALNRAVDAT-------REAQELNSRNQERLEEALQRKQELSRDN-ATLQA 2428
Query: 2332 LIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEA 2391
+ AA D + + + L A
Sbjct: 2429 TLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAA 2488
Query: 2392 THHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXN 2451
HA L + A +L + N + TQ Q + +
Sbjct: 2489 EAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADH 2548
Query: 2452 VTKLNRILDERVRPARERSSSLLADATKAQHAV---DQKLLPNLTATEEVLRKIRDHLSR 2508
T + V +R+ LLA++T + A+ Q+L A + ++RD ++
Sbjct: 2549 -TWATVVRQGLV----DRAQQLLANSTALEEAMLQEQQRLGLVWAALQGARTQLRDVRAK 2603
Query: 2509 ADDDDNAIQXXXXXXXXXXXXXXXN--KADRVNATI-GTTFSVMSHLGPELATSKDWAQT 2565
D + IQ A V A T V S L + W
Sbjct: 2604 KDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQ 2663
Query: 2566 LPKLADEGQKMTSNVESHLKNINDMEPQISSSYHTVK-MXXXXXXXXXXXXXXKLQKLKD 2624
L GQ + V +++ +E + + + + ++++
Sbjct: 2664 YEGL--RGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLALSASIGRVRE 2721
Query: 2625 LVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFRTKE-------KDGF 2677
L+ QAR A++++V + F+ S +Q R P + +++ T + Y + E +D F
Sbjct: 2722 LIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPGQGTEDRF 2781
Query: 2678 ILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRW 2737
++Y+G+ R + DYM + +++ + V +G++ PA +SID+ + + ++
Sbjct: 2782 VMYMGS-------RQATGDYMGVSLRDKKVHWVYQLGEAG-----PAVLSIDEDIGE-QF 2828
Query: 2738 YQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-A 2796
V +DR + +S+ +T + PG + NL + YVGG PS
Sbjct: 2829 AAVSLDRTLQFGHMSVTVERQMIQET--KGDTVAPGAEGLLNLRPDDFVFYVGGYPSTFT 2886
Query: 2797 KLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSG----PQEYRF 2852
+ FP + G IE + + V L+NF +L A R S +G
Sbjct: 2887 PPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGSYL 2946
Query: 2853 DGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLG 2912
DG G+A ++ ++ + + R + +G+++ + + F L +Q+G + L G
Sbjct: 2947 DGTGFARISFDSQIS-TTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLYDFG 3005
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 18/218 (8%)
Query: 3456 FMGCLKGLLMNGQQVTRIGNAVNALRCV-DNIEDGVYFEASNNTHSNYLKLLENFKVGDE 3514
F GC+K L ++G+ + C+ +E G++F S + L +
Sbjct: 3482 FSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGV----ITLDLPGATLPD 3537
Query: 3515 VSISMEVRPRNTTGLLLSVHGKKD--YMVLELLDSEVVANVENGNGPFRATYKLSNKHYL 3572
V + +EVRP TGL+ + + Y+ L++ + +V+ ++G G F + ++ L
Sbjct: 3538 VGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTS--VTRPSVL 3595
Query: 3573 CDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAY--TSTDTHSALYIGGHERPIHKVRGVH 3630
CDG WH++ D S +G + + LY+GG P+ V+
Sbjct: 3596 CDGQWHRLAVMKSGNVLRLEVDAQ-SNHTVGPLLAAAAGAPAPLYLGGLPEPM-AVQPWP 3653
Query: 3631 SRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGV--CP 3666
+ GC+R + V +PV + S GA VG CP
Sbjct: 3654 P--AYCGCMRRLAVNRSPVAMTRSVEVHGA-VGASGCP 3688
Score = 40.7 bits (91), Expect = 0.097
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 15/178 (8%)
Query: 3488 DGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLL---SVHGKKDYMVLEL 3544
D F S ++H ++ +L + + S+SM V PR++ GLLL + + L L
Sbjct: 3334 DSYQFGGSLSSHLEFVGILARHR--NWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFL 3391
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDG--HFSKPGI 3602
+ VA +E RA + ++ G WHK+ DG +S+ G
Sbjct: 3392 SNGHFVAQMEGLGTRLRAQSRQRSR----PGRWHKVSVRWEKNRILLVTDGARAWSQEGP 3447
Query: 3603 GAYTSTDTH---SALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVG 3657
H L++GG H + + GF+GCV+ + + P+ P G
Sbjct: 3448 HRQHQGAEHPQPHTLFVGGLPASSHSSK-LPVTVGFSGCVKRLRLHGRPLGAPTRMAG 3504
>AB067494-1|BAB67800.1| 1737|Homo sapiens KIAA1907 protein protein.
Length = 1737
Score = 1268 bits (3142), Expect = 0.0
Identities = 657/1784 (36%), Positives = 931/1784 (52%), Gaps = 133/1784 (7%)
Query: 130 FGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATN 189
FG ++L+ IT+DD+ IC+TEYS+IVPLE+GEI +SL+N RP + + S +L+E+T+ATN
Sbjct: 2 FGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATN 61
Query: 190 VRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNL 249
VRLR LRT LLGHLM A +DPTVTRRY+YSIKDISIGGRC+C+GHAD C+ DP
Sbjct: 62 VRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPF 121
Query: 250 NILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
L C CQHNTCG C++CC GF Q+ W+ + C+ CNC+ H T+C YDPE+D +
Sbjct: 122 R-LQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRR 180
Query: 310 RLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST 369
R S ++G Y+GGG C++CQH+T G+NC +C P +YR D VC+ C C+ F+
Sbjct: 181 RASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTD 240
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKP--------------------CTCN 409
G CE+ +GRC CRP F C CA G+ +P+C P C C+
Sbjct: 241 GTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCS 300
Query: 410 LNGTEGEHCT--PTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLT 467
GT+G C P G C CK N+ G CE+C G+Y P C+ C+C++ G CD T
Sbjct: 301 AAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDT 360
Query: 468 GDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC 527
G C C+ + G TC++C GY+++P C+ C C +GT P CD+ +G+C+C+ F GP C
Sbjct: 361 GQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHC 419
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
D+C GY+ C C CDP G+ C A G C C + G C +CSPG++ +
Sbjct: 420 DRCRPGYH-----GFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGF 474
Query: 588 PDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVT 646
P C+ C+C GS+ + CD +G C C+ G +CDTC YN+P CE +C P G+
Sbjct: 475 PSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLA 534
Query: 647 ASFAGCGSVPAGEL-CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
++P ++ C C+ V+G C+ CKP +W L NP GC +C+C+L GTL +
Sbjct: 535 PVDP---ALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVA 591
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
C +GQC CK HV + C C DGF+ L D FGC C CDIGG++ +C+ TG C
Sbjct: 592 ECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVC 651
Query: 766 HCHSRVEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSG-PVRYRNSEEVFPEYSWKGYVV 824
C +G C +P R HY P LH + E+E+ T G +R+ + F +SW+GY
Sbjct: 652 RCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAMRFGFNPLEFENFSWRGYAQ 711
Query: 825 FSLLQNEVINIIQITKSSLYRMVLKYANPLRDPVVANIVITPES-----VVDIQQKFNVY 879
+ +Q ++ + +T L+ +V +Y N V + + E Q V
Sbjct: 712 MAPVQPRIVARLNLTSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANCTAQSQPVA 771
Query: 880 LRPTVLPQLVTVAGDKGVTPAPFVMNPGNWTVTIKTNKEIMIDYFVLIPEAYYEATILTK 939
P+ P +TV +G PFV+NPG W + ++ + +++DY VL+P AYYEA +L
Sbjct: 772 FPPSTEPAFITVP-QRGFGE-PFVLNPGTWALRVEA-EGVLLDYVVLLPSAYYEAALLQL 828
Query: 940 MVDKPCIV-------GDKKLCRQFAYPSLSGKSTADVTSLVTSVDSFIDDPVQLSELKVE 992
V + C GD C + + L G +A + D+ + P +L
Sbjct: 829 RVTEACTYRPSAQQSGDN--CLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQLS-- 884
Query: 993 PNTIPILRTT-----LQYNMRIEKPGQYVLLVEYVTPAARNQDLNTGNSTYSSVVKTPVT 1047
P+ P++ T +Q + + +PG+Y L+VEY AR + V TP
Sbjct: 885 PSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANEDARQE--------VGVAVHTP-- 934
Query: 1048 IKFQSGPDDQHLVETDGIINFNDCPYTAPCRQVMVDDYSRIQFVTVTDPNNVVFLLDQPD 1107
Q P G+++ + C Y+ CR D + + +V +Q
Sbjct: 935 ---QRAPQQ-------GLLSLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQ-- 982
Query: 1108 TEAAIKSVVAIPQAEWHLDYLTPRPYCLRRNGR-------CDPAVF----NAVV--DAKK 1154
+ V +P E+ +++ PR C+ +G C P+ F ++ D +
Sbjct: 983 ARFFLHGVTLVPIEEFSPEFVEPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQV 1042
Query: 1155 VEFESGT--------------GGDRETRPQILNNSTTVVYLPTQSEPVILEGKVSAPGEY 1200
+ G G R P ++ L V+ V G Y
Sbjct: 1043 IPLPPGLPLTHAQDLTPAMSPAGPRPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRY 1102
Query: 1201 LFMVHYYQPDHPESTMEVTVNTDGQKQETNLPIQHCPSNSGCRALLRKPDTSTSFLVNEN 1260
F++H YQP HP +EV +N G+ + + CP GCR L+ + + +
Sbjct: 1103 AFLLHGYQPAHPTFPVEVLINA-GRVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSE 1161
Query: 1261 FTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNETG 1320
T+ + + +WLDYVLV+ + ++ L E LD + +FI CA+ Y+ISP+ +
Sbjct: 1162 LTVTVRVPEGRWLWLDYVLVVPENVYSFGYLREEP-LDKSYDFISHCAAQGYHISPSSSS 1220
Query: 1321 L-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
L CR A S++ YN+GARPC C +G+T C FGGQCPC +VIGR CS C TGY+G
Sbjct: 1221 LFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWG 1280
Query: 1380 FPNCRPCHCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVV 1438
FPNCRPC C +CD+ G CICP +C C+P TF GC++CNC+ G+
Sbjct: 1281 FPNCRPCDC-GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQ 1339
Query: 1439 G-NQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ DSG+C CR NV GR CD C PG + +P C C C+ GT VCD T QC
Sbjct: 1340 ELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQC 1399
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPV 1557
YCK NV+G CD C F+L NP GCT+CFCFG T RC SS YT +M W
Sbjct: 1400 YCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGW--- 1456
Query: 1558 DVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNG-KVAYFGAPEYYLGKRLTSYGGYL 1616
VL++ ++ PHE P + + + V Y+ AP YLG R++SYGG L
Sbjct: 1457 -VLLSTDRQVVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTL 1515
Query: 1617 TYTVH-YTTRGD--GDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEF-ST 1672
Y +H T RGD + PDV++ G + P G ++L E F T
Sbjct: 1516 RYELHSETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHT 1575
Query: 1673 LDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATS 1732
V+R++ M L ++ L IRA + + S SL V LE+ G A++
Sbjct: 1576 ETRNTVSREELMMVLASLEQLQIRALFSQISSAVSLRRVALEVASPAGQG-----ALASN 1630
Query: 1733 VEECQCPRAYRGLSCEQCAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGICLNCADNT 1788
VE C CP +YRG SC++CA G YR L G CVPCQC+GHSD+C +G+C++C NT
Sbjct: 1631 VELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNT 1690
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDL 1832
G HCE C +G+ C+ C CP+ PSNNFA C L
Sbjct: 1691 EGAHCERCQAGFMSSRD-DPSAPCVSCPCPLSVPSNNFAEGCVL 1733
Score = 175 bits (427), Expect = 2e-42
Identities = 112/346 (32%), Positives = 146/346 (42%), Gaps = 51/346 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHS---DQCDVNTGICLNCADNTIGD 1791
+C+C + G +C++CA G++ P C C C+ + CD G CL C G
Sbjct: 362 QCRCRVGFEGATCDRCAPGYFHFP--LCQLCGCSPAGTLPEGCD-EAGRCL-CQPEFAGP 417
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
HC+ C GYHG +C C C P C G L C C+PGY G
Sbjct: 418 HCDRCRPGYHGFP------NCQACTCD---PRGALDQLCGA---GGL--CRCRPGYTGTA 463
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
C+ C+ G++G P C PC+CS + +CD +G C C G C+
Sbjct: 464 CQECSPGFHGFPS---------CVPCHCSAEGSLH--AACDPRSGQC-SCRPRVTGLRCD 511
Query: 1912 LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGT----CVCRPGVIGEKCDRCAPDHWG 1967
C PG Y C A C G+A D C+CR V G CDRC P WG
Sbjct: 512 TCVPGAYNFPY----CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWG 567
Query: 1968 LNTGL--GCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD--- 2019
L+ GCT C+C G +C GQC C V G+ C C GF+ +
Sbjct: 568 LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYF 627
Query: 2020 GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP 2064
GC C C+ G ++G C TG C C P G C P R +P
Sbjct: 628 GCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE-PARDHYLP 672
Score = 172 bits (419), Expect = 2e-41
Identities = 116/363 (31%), Positives = 152/363 (41%), Gaps = 56/363 (15%)
Query: 1728 RRATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHS---DQCDVNTGICLNC 1784
R+ V C C ++G CE CA G Y P C PCQC+ D+CD +TG C C
Sbjct: 310 RKDPRVGRCLCKPNFQGTHCELCAPGFYG-PG--CQPCQCSSPGVADDRCDPDTGQC-RC 365
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
G C+ C GY C +C C P+ CD E G C CQ
Sbjct: 366 RVGFEGATCDRCAPGYFHFPL------CQLCGCS---PAGTLPEGCD--EAGR---CLCQ 411
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP-GSCDSI--NGDCLKC 1901
P + G C+ C GY+G P C+ C C DP G+ D + G +C
Sbjct: 412 PEFAGPHCDRCRPGYHGFPN---------CQACTC-------DPRGALDQLCGAGGLCRC 455
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCD 1959
G AC C+PGF+G +C C C G A CD +G C CRP V G +CD
Sbjct: 456 RPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCD 511
Query: 1960 RCAPDHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
C P + C P G+A + C C V G CD+C GFW +
Sbjct: 512 TCVPGAYNFPYCEAGSCHPA--GLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLS 569
Query: 2018 K---DGCDHCNCNTGYSVGFMCNA---TGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
+GC C+C+ ++G + TGQC C P V G+ C C + + + Q C
Sbjct: 570 PSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGC 629
Query: 2072 DSC 2074
SC
Sbjct: 630 RSC 632
Score = 169 bits (410), Expect = 2e-40
Identities = 112/391 (28%), Positives = 159/391 (40%), Gaps = 62/391 (15%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC----DVNT---- 1778
+C C G +C++C G + P + C C C GH+ C +V+
Sbjct: 124 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 183
Query: 1779 ----------GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNF 1826
G+C++C +T G +CE C+ G++ + +P C C C +
Sbjct: 184 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTC 243
Query: 1827 ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE-----DTDLHTGDYCKP----- 1876
DL+ C C+P + G RC+ CA G+ G P + T + P
Sbjct: 244 E---DLTGR-----CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIV 295
Query: 1877 -CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF 1935
C+CS + D G CL C N G C LCAPGFYG C C C
Sbjct: 296 NCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG-----PGCQPCQCSSP 349
Query: 1936 GMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG 1993
G+AD CD TG C CR G G CDRCAP ++ C C C A + D+ G
Sbjct: 350 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDEAG 406
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+C C G CD+C G+ + C C C+ ++ +C A G C C PG G C
Sbjct: 407 RCLCQPEFAGPHCDRCRPGYHGF--PNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTAC 464
Query: 2054 DRCPERWVLIPQEGCLECDSCTDALIFSVED 2084
C + P C+ C + + + D
Sbjct: 465 QECSPGFHGFP--SCVPCHCSAEGSLHAACD 493
Score = 166 bits (403), Expect = 2e-39
Identities = 118/334 (35%), Positives = 151/334 (45%), Gaps = 57/334 (17%)
Query: 1757 LPSGFCVPCQCN-----GHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRD 1811
LP+G V C C+ G++ + D G CL C N G HCE C G++G
Sbjct: 289 LPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG------- 340
Query: 1812 CLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTG 1871
C C C P +++ CD + G C C+ G+ GA C+ CA GY+ P
Sbjct: 341 CQPCQCSSPGVADD---RCD-PDTGQ---CRCRVGFEGATCDRCAPGYFHFP-------- 385
Query: 1872 DYCKPCNCS--GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA 1929
C+ C CS G + P CD G CL C AG C+ C PG++G NC A
Sbjct: 386 -LCQLCGCSPAGTL----PEGCDEA-GRCL-CQPEFAGPHCDRCRPGYHG----FPNCQA 434
Query: 1930 CICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASEST 1986
C CD G D C + G C CRPG G C C+P G + C PC+C S
Sbjct: 435 CTCDPRGALDQLCGAG-GLCRCRPGYTGTACQECSPGFHGFPS---CVPCHCSAEGSLHA 490
Query: 1987 QCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN-TGYSV--GFMCNATGQCE 2043
CD +GQC C VTG +CD C G +N+ C+ +C+ G + + A C
Sbjct: 491 ACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPY--CEAGSCHPAGLAPVDPALPEAQVPCM 548
Query: 2044 CLPGVIGEKCDRC-PERWVLIPQ--EGCLECDSC 2074
C V G CDRC P W L P EGC C SC
Sbjct: 549 CRAHVEGPSCDRCKPGFWGLSPSNPEGCTRC-SC 581
Score = 160 bits (388), Expect = 1e-37
Identities = 104/340 (30%), Positives = 139/340 (40%), Gaps = 46/340 (13%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCNGH--SDQCDVNTGICLNCADNTI 1789
C G++CE+C G YR P+ C C C C+ TG C C N
Sbjct: 199 CQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY-CRPNFS 257
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGS----------LI 1839
G+ C+ C G+ G + P+ ++CD S G+ +
Sbjct: 258 GERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQI-VNCDCSAAGTQGNACRKDPRVG 316
Query: 1840 SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
C C+P + G CE CA G+Y G C+PC CS D CD G C
Sbjct: 317 RCLCKPNFQGTHCELCAPGFY----------GPGCQPCQCSSPGVADD--RCDPDTGQC- 363
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEK 1957
+C GA C+ CAPG++ + C C C G CD G C+C+P G
Sbjct: 364 RCRVGFEGATCDRCAPGYFHFPL----CQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPH 418
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
CDRC P + G C C C Q G CRC G TG C +C+ GF +
Sbjct: 419 CDRCRPGYHGFP---NCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGF- 474
Query: 2018 KDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C C+C+ S+ C+ +GQC C P V G +CD C
Sbjct: 475 -PSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTC 513
Score = 159 bits (386), Expect = 2e-37
Identities = 105/349 (30%), Positives = 145/349 (41%), Gaps = 54/349 (15%)
Query: 1765 CQCNGHSDQCDVNTG-----ICLNCADNTIGDHCEFCMSGYHGD----ATVGTPRDCLIC 1815
C C+GH+D CD + C NT G C+ C G++ AT + +C C
Sbjct: 103 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 162
Query: 1816 AC---------PMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDT 1866
C + S D + G + +CQ G CE C G+Y P
Sbjct: 163 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 222
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-----DA 1921
L + C+ CNC + G+C+ + G C C N +G C++CA GF G
Sbjct: 223 -LDSPHVCRRCNCESDFTD---GTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPT 277
Query: 1922 IFSKNCTA-----------CICDEFGMAD--C--DSTTGTCVCRPGVIGEKCDRCAPDHW 1966
S N T C C G C D G C+C+P G C+ CAP +
Sbjct: 278 PSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY 337
Query: 1967 GLNTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH 2023
G GC PC C G+A + +CD D GQCRC G G CD+CA G++++ C
Sbjct: 338 GP----GCQPCQCSSPGVADD--RCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL--CQL 389
Query: 2024 CNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECD 2072
C C+ ++ C+ G+C C P G CDRC + P CD
Sbjct: 390 CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCD 438
Score = 134 bits (323), Expect = 8e-30
Identities = 69/187 (36%), Positives = 93/187 (49%), Gaps = 17/187 (9%)
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDE 1934
+PC C + P +C+ G C C + G C+ CA G++G NC C C
Sbjct: 1239 RPCGCH-EVGATGP-TCEPFGGQC-PCHAHVIGRDCSRCATGYWG----FPNCRPCDC-- 1289
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC---GIAS-ESTQCDD 1990
G CD TG C+C P I C C P +G + +GC CNC GI CD
Sbjct: 1290 -GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1348
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVI 2049
D+GQC+C VTG++CD C+ GF Y + C C+C+ + +C+ TGQC C V
Sbjct: 1349 DSGQCKCRPNVTGRRCDTCSPGFHGYPR--CRPCDCHEAGTAPGVCDPLTGQCYCKENVQ 1406
Query: 2050 GEKCDRC 2056
G KCD+C
Sbjct: 1407 GPKCDQC 1413
Score = 114 bits (274), Expect = 7e-24
Identities = 65/195 (33%), Positives = 85/195 (43%), Gaps = 30/195 (15%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C G C CA GY+G P C+PC+C + CD + G C+
Sbjct: 1260 CPCHAHVIGRDCSRCATGYWGFPN---------CRPCDCGARL-------CDELTGQCI- 1302
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD-----CDSTTGTCVCRPGVIG 1955
C T C LC P +G C C C G+ + CD+ +G C CRP V G
Sbjct: 1303 CPPRTIPPDCLLCQPQTFGCHPLV-GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTG 1361
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
+CD C+P G C PC+C A + CD GQC C + V G +CDQC+ G +
Sbjct: 1362 RRCDTCSPGFHGYPR---CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTF 1418
Query: 2015 NY---TKDGCDHCNC 2026
+ GC C C
Sbjct: 1419 SLDAANPKGCTRCFC 1433
Score = 57.2 bits (132), Expect = 1e-06
Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 9/93 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C Y G C+ CA G+Y + L G C PC C G+ + PGS G C+
Sbjct: 1634 CLCPASYRGDSCQECAPGFYR--DVKGLFLGR-CVPCQCHGHSDRCLPGS-----GVCVD 1685
Query: 1901 CVNNTAGAACNLCAPGFYGDAIF-SKNCTACIC 1932
C +NT GA C C GF S C +C C
Sbjct: 1686 CQHNTEGAHCERCQAGFMSSRDDPSAPCVSCPC 1718
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/108 (31%), Positives = 46/108 (42%), Gaps = 9/108 (8%)
Query: 1884 NPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGD--AIFSKNCTACICDEFGMAD-C 1940
+P G+ S CL C + G +C CAPGFY D +F C C C G +D C
Sbjct: 1620 SPAGQGALASNVELCL-CPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC--HGHSDRC 1676
Query: 1941 DSTTGTCV-CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCGIASES 1985
+G CV C+ G C+RC + C C C ++ S
Sbjct: 1677 LPGSGVCVDCQHNTEGAHCERCQAGFMSSRDDPSAPCVSCPCPLSVPS 1724
Score = 42.7 bits (96), Expect = 0.024
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 16/109 (14%)
Query: 424 LCPCKYNYAGKSCEICEDGYYSP-------ECKNCECNTVGSVSYVCDKLTGDCT-CKSK 475
LC C +Y G SC+ C G+Y C C+C+ S C +G C C+
Sbjct: 1633 LCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCH---GHSDRCLPGSGVCVDCQHN 1689
Query: 476 YSGRTCNQCQAGYYNY---PTCKPCNCDTSGTEPSICDDVSGQCICKAG 521
G C +CQAG+ + P+ +C + PS ++ + C+ + G
Sbjct: 1690 TEGAHCERCQAGFMSSRDDPSAPCVSCPCPLSVPS--NNFAEGCVLRGG 1736
Score = 38.7 bits (86), Expect = 0.39
Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 14/103 (13%)
Query: 1777 NTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENG 1836
N +CL C + GD C+ C G++ D C+ C C + ++ L G
Sbjct: 1630 NVELCL-CPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC---HGHSDRCLP------G 1679
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC 1879
S + +CQ GA CE C AG+ +D C C C
Sbjct: 1680 SGVCVDCQHNTEGAHCERCQAGFMSSRDDPSAP----CVSCPC 1718
Score = 38.7 bits (86), Expect = 0.39
Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 7/85 (8%)
Query: 1995 CRCAKGVTGKQCDQCAAGFWNYTK----DGCDHCNCNTGYSVGFMCNATGQC-ECLPGVI 2049
C C G C +CA GF+ K C C C+ G+S + +G C +C
Sbjct: 1634 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCH-GHSDRCL-PGSGVCVDCQHNTE 1691
Query: 2050 GEKCDRCPERWVLIPQEGCLECDSC 2074
G C+RC ++ + C SC
Sbjct: 1692 GAHCERCQAGFMSSRDDPSAPCVSC 1716
Score = 35.9 bits (79), Expect = 2.8
Identities = 25/115 (21%), Positives = 44/115 (38%), Gaps = 5/115 (4%)
Query: 602 GSTCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G+ + LC C +++ G C C FY + C P C +P +
Sbjct: 1625 GALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRC--LPGSGV 1682
Query: 661 C-QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKSGQ 713
C C+ +G C C+ + + ++ C C C L+ N+ C + G+
Sbjct: 1683 CVDCQHNTEGAHCERCQAGFMSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGR 1737
>AY327116-1|AAQ72571.1| 3277|Homo sapiens laminin alpha 3 splice
variant b2 protein.
Length = 3277
Score = 867 bits (2145), Expect = 0.0
Identities = 529/1618 (32%), Positives = 766/1618 (47%), Gaps = 151/1618 (9%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE--EESGRCECRPEFQPPDCSSCAYGYFD 399
PT R Y ++ + C C+ H N E+ RCEC+ C C GY +
Sbjct: 280 PTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY-N 338
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSV 459
+P + C C C + +A +C YY P+ + + +
Sbjct: 339 QRRWRPAAWE----QSHECEA----CNC-HGHAS-NC------YYDPDVERQQASLNTQG 382
Query: 460 SYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYN---YPT-----CKPCNCDTSGTEPSICD 510
Y G C C+ +G C QC GYY P C PC+CD + C+
Sbjct: 383 IYAGG---GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CE 437
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP----------------CNCDPTG 554
SG+C CK F G C++C GYY P C+C+ G
Sbjct: 438 QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEG 497
Query: 555 STSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHC 613
C A G+C C G +CD C G+Y +P C +C C GS C G C C
Sbjct: 498 VLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCEC 557
Query: 614 KSNFDGAKCDTCREQFYNYPACEECN--CDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
+ G +CD C Y++P C+ + CDP G S G CQCK V+G
Sbjct: 558 RPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLG--------YCQCKLHVEGPT 609
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG 731
C+ CK LYWNL + NP GC +C C+ AGT++ G C G C CK HVG CD C DG
Sbjct: 610 CSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDG 669
Query: 732 FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQF 791
++ L+ ++ FGC C CDIGG++ + C +G C C V G+ C +P +YFP LH
Sbjct: 670 YFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHM 729
Query: 792 QYEVEDGVTQSG-PVRYRNSEEVFPEYSWKGYVVFSLLQNEVINIIQITKSS--LYRMVL 848
+YE+EDG T +G +R+ FPE+SW+GY + +QN+V + + KSS L+R++L
Sbjct: 730 KYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVIL 789
Query: 849 KYANPLRDPVVANIVITPESVVDIQQKFNVYLRPTVLPQLVTVAGDKGVTPAPFVMNPGN 908
+Y NP + V +I I P S Q K ++L P+ P VTV G+ G PF + PG
Sbjct: 790 RYVNPGTEAVSGHITIYP-SWGAAQSKEIIFL-PSKEPAFVTVPGN-GFAD-PFSITPGI 845
Query: 909 WTVTIKTNKEIMIDYFVLIPEAYYEATILTKMVDKPCIVGDKKLCRQFAYPSLSGKSTAD 968
W IK + +++DY VL+P YYEA++L V +PC Y L T
Sbjct: 846 WVACIKA-EGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLP--VTRF 902
Query: 969 VTSLVTSVDSFIDD----PVQLSE-LKVEPNTIPILRTTLQYNMRIEKP--GQYVLLVEY 1021
+L F+ D PV + + P + + ++ ++R+ P G YV++VEY
Sbjct: 903 PCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEY 962
Query: 1022 VTPAARNQDLNTGNSTYSSVVKTPVTIKFQSGPDDQHLVETDGIINFNDCPYTAPCRQVM 1081
T AA+ ++ + SV+ G +N C Y+ CR +
Sbjct: 963 STEAAQLFVVDVNVKSSGSVLA--------------------GQVNIYSCNYSVLCRSAV 1002
Query: 1082 VDDYSRIQFVTVTDPNNVVFLLDQPDTEAAIKSVVAIPQAEWHLDYLTPRPYCLRRNGRC 1141
+D SRI + ++ L + V IP E+ +Y+ P+ +C+ GR
Sbjct: 1003 IDHMSRIAMYELLADADIQ--LKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRF 1060
Query: 1142 DPAVFNAVVDAKKVE-----FESGTGGDRETRPQILNNSTTV---VYLPTQSEPVILEGK 1193
V A + + +G PQ + S V V L V L G+
Sbjct: 1061 VNQSATCVSLAHETPPTALILDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGR 1120
Query: 1194 VSAPGEYLFMVHYYQPDHPESTMEVTVNTDGQKQETNLPIQHCPSNSGCRALLRKPDTST 1253
V G Y+F++H+YQ HP +V+V+ G + + CP GCR +
Sbjct: 1121 VPHLGRYVFVIHFYQAAHPTFPAQVSVD-GGWPRAGSFHASFCPHVLGCRDQVIAEGQIE 1179
Query: 1254 SFLVNENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYY 1313
+ K K + L VLV+ A ++ +L + + +D + EFI C ++Y
Sbjct: 1180 FDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKS-MDKSLEFITNCGKNSFY 1238
Query: 1314 ISPNETG-LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+ P C+ + S+ + Y+ GA PC C G+T C+ GGQCPC+PNVIGR C+
Sbjct: 1239 LDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTR 1298
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
C TG+YGFP C+PC C +C++ G C CP C+ C+ ++F+F GC+ CN
Sbjct: 1299 CATGHYGFPRCKPCSC-GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCN 1357
Query: 1432 CNPLGVVGNQL-QCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVC 1490
C+ G + + +C+ DSG+C C+ + GR CD C G Y FP+C C CNR GT VC
Sbjct: 1358 CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVC 1417
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDE 1550
D T C CK NV G C+ C+E F+L N GCT CFCFG +C SS+ +
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVD 1477
Query: 1551 MVDWYPVDVLINNTIELYPHEDVPELTN--VTVLTVGLNDGVTNGKVAYFGAPEYYLGKR 1608
M+ W+ +E D+P N + L + A + AP YLG +
Sbjct: 1478 MLGWH---------LETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDK 1528
Query: 1609 LTSYGGYLTYTV-HYTTRGDGDAV-AAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLS 1666
++SYGGYLTY + GD + PDV + G + +++ P V +
Sbjct: 1529 VSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVV 1588
Query: 1667 EEEFSTLDG-APVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDEL 1725
E F APV+R++ M L ++ + I+ Y+ + +LS V LE D G
Sbjct: 1589 EGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSG--- 1645
Query: 1726 VVRRATSVEECQCPRAYRGLSCEQCAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGIC 1781
R A +VE C CP AY G SC+ C+ G+YR L +G CVPC CNGHS+QC +GIC
Sbjct: 1646 --RIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGIC 1703
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
+NC NT G+HCE C GY+G+A G+ R ACP P+ +N+FA C + NG + C
Sbjct: 1704 VNCQHNTAGEHCERCQEGYYGNAVHGSCR-----ACPCPH-TNSFATGCVV--NGGDVRC 1755
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
+C+ GY G +CE CA GY+G P+ G C+PC+C+ N GSC + GDC+
Sbjct: 1756 SCKAGYTGTQCERCAPGYFGNPQ----KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 1806
Score = 626 bits (1547), Expect = e-178
Identities = 278/630 (44%), Positives = 377/630 (59%), Gaps = 42/630 (6%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CD C++ + K HP A+D WWQSPPLS G +YN VNLT+DLGQ FHVAY+ +K
Sbjct: 102 CDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFA 161
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G T+ PWQYF+ S DC + FG+E+ +T+DD V+C TEYS+I
Sbjct: 162 NSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRI 221
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GE+ +SL+N RP + + S L+E+T+ATN+RLR LRT LLGHL+S A++DPT
Sbjct: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGG+C+CNGHA+ C +P + C CQH+TCG C++CC+G+
Sbjct: 282 VTRRYYYSIKDISIGGQCVCNGHAEVCNINNPE---KLFRCECQHHTCGETCDRCCTGYN 338
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q++WR + CE CNCH H + C YDP+++ ++ SL+ G Y GGG C+NCQHNT
Sbjct: 339 QRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTA 398
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C YYRPYG D D C PC CDP + G CE+ SGRC C+P F +C C
Sbjct: 399 GVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRCHCKPNFHGDNCEKC 457
Query: 394 AYGYFDYPNC---------------------KPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
A GY+++P C K C CNL G E C G C C+
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVE 516
Query: 433 GKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
G C+ C G+YS P C+ C C+ +GS C +TG C C+ +G+ C++C +G Y++
Sbjct: 517 GPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDF 576
Query: 492 PTCKPCN--CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
P C+ + CD +GT + G C CK GP C +C Y+ C C
Sbjct: 577 PHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECK 632
Query: 550 CDPTGSTSTS--C-SADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI 601
C G+ S + C DG C+C ++ GG CD C GY+ Y C C CD+ G++
Sbjct: 633 CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGAL 692
Query: 602 GSTCD-DNGLCHCKSNFDGAKCDTCREQFY 630
S C +G+C C+ + G C +Y
Sbjct: 693 SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 171 bits (416), Expect = 4e-41
Identities = 115/356 (32%), Positives = 161/356 (45%), Gaps = 53/356 (14%)
Query: 1738 CPRAYRGLSCEQCAEGHYR-------LPSGFCVPCQCNG-HSDQCDVNTGICLNCADNTI 1789
C G++CEQCA+G+YR P G C+PC C+ H+D C+ +G C +C N
Sbjct: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-CIPCSCDPEHADGCEQGSGRC-HCKPNFH 450
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS-----CDLSENGSLIS---- 1840
GD+CE C GY+ P I P+ PS+ ++ CD + G L
Sbjct: 451 GDNCEKCAIGYYN-----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 505
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD 1897
C C+PG G RC+ C +G+Y P C+ C CS + Q P C S+ G
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP---------ICQACWCSALGSYQMP--CSSVTGQ 554
Query: 1898 CLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
C +C G C+ C G Y + +AC D G + S G C C+ V G
Sbjct: 555 C-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC--DPAGTIN--SNLGYCQCKLHVEGPT 609
Query: 1958 CDRCAPDHWGLN--TGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAG 2012
C RC +W L+ GC+ C C G S + +C +G C C V G CD C G
Sbjct: 610 CSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDG 669
Query: 2013 FWNYTKD---GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIP 2064
++ K GC C C+ G ++ MC+ +G C+C V+G+ C R PE P
Sbjct: 670 YFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR-PENNYYFP 724
Score = 169 bits (410), Expect = 2e-40
Identities = 118/388 (30%), Positives = 161/388 (41%), Gaps = 71/388 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRL---PSGF-----CVPCQCNGHSDQC-----------DV 1776
C+C G +C++C G+ + P+ + C C C+GH+ C +
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 1777 NT-------GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICACPMPYPSNNFA 1827
NT G+C+NC NT G +CE C GY+ V P C+ C+C +
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH------ 432
Query: 1828 LSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-------------EDTDLHTGDYC 1874
D E GS C+C+P + G CE CA GYY P D GD
Sbjct: 433 --ADGCEQGSG-RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI- 488
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDE 1934
K C+C N+ P CD+ +G CL C G C+ C GFY I C AC C
Sbjct: 489 KGCDC--NLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSA 540
Query: 1935 FG--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDN 1992
G C S TG C CRPGV G++CDRC + G + C A + +
Sbjct: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAG---TINSNL 596
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV---GFMCNATGQCECLP 2046
G C+C V G C +C +WN K+ GC C C+ +V G G C C
Sbjct: 597 GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKS 656
Query: 2047 GVIGEKCDRCPERWVLIPQEGCLECDSC 2074
V G+ CD C + + + + C C
Sbjct: 657 HVGGDSCDTCEDGYFALEKSNYFGCQGC 684
Score = 139 bits (337), Expect = 2e-31
Identities = 97/341 (28%), Positives = 144/341 (42%), Gaps = 42/341 (12%)
Query: 231 CMCNG-HADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C C+ HAD CE +G C C+ N G C KC G+ + + R
Sbjct: 426 CSCDPEHADGCEQG--SGR-----CHCKPNFHGDNCEKCAIGYYNFPFCL-----RIPIF 473
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
P + + D + + L + + G+CL C+ EG C+ CR +Y
Sbjct: 474 PVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFY---- 528
Query: 350 KRWDELDVCQPCQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCT- 407
+CQ C C S C +G+CECRP C C G +D+P+C+ +
Sbjct: 529 ----SFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSS 584
Query: 408 -CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE------CKNCECNTVGSVS 460
C+ GT + G C CK + G +C C+ Y++ + C C+C+ G+VS
Sbjct: 585 ACDPAGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVS 640
Query: 461 YV--CDKLTGDCTCKSKYSGRTCNQCQAGYY-----NYPTCKPCNCDTSGTEPSICDDVS 513
C + GDC CKS G +C+ C+ GY+ NY C+ C CD G S+C S
Sbjct: 641 GTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPS 700
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
G C C+ G C + + YY L + + P G
Sbjct: 701 GVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
Score = 136 bits (330), Expect = 1e-30
Identities = 102/347 (29%), Positives = 147/347 (42%), Gaps = 54/347 (15%)
Query: 1765 CQCNGHSDQCDVNTGICL---NCADNTIGDHCEFCMSGYH----GDATVGTPRDCLICAC 1817
C CNGH++ C++N L C +T G+ C+ C +GY+ A +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1818 PMPYPSNNF----------ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTD 1867
+ SN + +L+ G + NCQ G CE CA GYY P
Sbjct: 359 -HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVP 416
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG------DA 1921
+ D C PC+C +P+ C+ +G C C N G C CA G+Y
Sbjct: 417 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIP 471
Query: 1922 IF-----------SKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
IF + + C C+ G+ CD+ G C+CRPGV G +CD C +
Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGPRCDTCRSGFYSF 530
Query: 1969 NTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN 2027
C C C + S C GQC C GVTG++CD+C +G +++ C+
Sbjct: 531 PI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587
Query: 2028 TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQE---GCLEC 2071
G + + G C+C V G C RC + + +E GC EC
Sbjct: 588 ---PAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSEC 631
Score = 127 bits (307), Expect = 7e-28
Identities = 72/206 (34%), Positives = 93/206 (45%), Gaps = 21/206 (10%)
Query: 1876 PCNC--SGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICD 1933
PC C +G P C G C C N G C CA G YG F + C C C
Sbjct: 1265 PCECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYG---FPR-CKPCSC- 1314
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG----IASESTQCD 1989
G C+ TG C C P + +C+ C + + GC CNC I + +CD
Sbjct: 1315 --GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECD 1372
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN-TGYSVGFMCNATGQCECLPGV 2048
D+GQCRC +TG+QCD+CA+GF+ + + C CNCN G G TG C C V
Sbjct: 1373 RDSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
Query: 2049 IGEKCDRCPERWVLIPQEGCLECDSC 2074
G +C+ C E + C SC
Sbjct: 1431 EGTECNVCREGSFHLDPANLKGCTSC 1456
Score = 125 bits (301), Expect = 3e-27
Identities = 153/764 (20%), Positives = 312/764 (40%), Gaps = 66/764 (8%)
Query: 2387 LTSEATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXX 2446
L EA HA L+ A L E+ + + + I
Sbjct: 2082 LVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAA 2141
Query: 2447 XXXXNV--TKLNRILDERVRPARERSSSLLADATKAQHAVDQKLLPNLTATEEVLRKIRD 2504
+ T + L + + S LL +A Q + Q++ P L ++ L +
Sbjct: 2142 SASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTV 2201
Query: 2505 HLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRVNATIGTTFSVMSHLGPELATSKDWA 2563
D + ++ + A V T V+ L P +
Sbjct: 2202 QKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIK 2261
Query: 2564 QTLPKLADEG-QKMTSNVESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKL 2622
T + +E +K ++ ++ + + + P + ++ + ++
Sbjct: 2262 DTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISD----NMDRI 2317
Query: 2623 KDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR---TKEKDG--- 2676
++L++QAR A+++ V + F+ S ++ RLP+ ++++ T +S + + ++E G
Sbjct: 2318 RELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTEN 2377
Query: 2677 -FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADN 2735
F++YLGN + S DY+ + + +G V ++GD A + +D+++ +
Sbjct: 2378 MFVMYLGN-------KDASRDYIGMAVVDGQLTCVYNLGDRE------AELQVDQILTKS 2424
Query: 2736 RWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA---DLPGH--HTIFNLDKEKSKLYV 2789
+ ++DR+ +R+ R + G + + D+ G +T+ NLD E YV
Sbjct: 2425 ETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYV 2484
Query: 2790 GGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGPQ 2848
GG P D KL +SFP ++G IE + + + L+NF L + +
Sbjct: 2485 GGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDK 2544
Query: 2849 EYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYL 2907
Y F+G GYA + + + P Q + +T GL++ G F SL ++DG++ +
Sbjct: 2545 NY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVDRGLLFFAENGDRFISLNIEDGKLMV 2600
Query: 2908 QVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLD 2967
+ L N+E G A N+G+ H + + + + ++ +V ++ ++
Sbjct: 2601 RYKL-NSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDV---QNTIIDGEVFDFS 2656
Query: 2968 TMNFGGNNKGI---LQVPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC----QFASL 3020
T GG I + F GCM+ + + L+ +++G+ C +
Sbjct: 2657 TYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLN---DTVGVTKKCSEDWKLVRS 2713
Query: 3021 VSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVN 3077
SF+ L F D+ +++ Q + F+T +P+G+L + + T+ ++ ++L +
Sbjct: 2714 ASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTR------NLQVTLED 2766
Query: 3078 G--KLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD 3119
G +L + TY D H ++V + S L+L++DD
Sbjct: 2767 GYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDD 2810
Score = 118 bits (283), Expect = 5e-25
Identities = 66/202 (32%), Positives = 85/202 (42%), Gaps = 25/202 (12%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCEC 381
GG+C CQ N G C +C +Y C+PC C CEE +G+C C
Sbjct: 1282 GGQC-PCQPNVIGRQCTRCATGHY--------GFPRCKPCSCGRRL----CEEMTGQCRC 1328
Query: 382 RPEFQPPDCSSC---AYGYFDYPNCKPCTCNLNGT---EGEHCTPTDGLCPCKYNYAGKS 435
P P C C ++ + C+ C C+ GT C G C CK G+
Sbjct: 1329 PPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQ 1388
Query: 436 CEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC 494
C+ C G+Y PEC C CN G+ VCD TG C CK G CN C+ G ++
Sbjct: 1389 CDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFH---L 1445
Query: 495 KPCNCDTSGTEPSICDDVSGQC 516
P N G C V+ QC
Sbjct: 1446 DPAN--LKGCTSCFCFGVNNQC 1465
Score = 114 bits (275), Expect = 5e-24
Identities = 61/178 (34%), Positives = 83/178 (46%), Gaps = 18/178 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C P Y G C+ C+ GYY + L+TG C PCNC+G+ N C +G C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVN 1705
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTG--TCVCRPGVIGE 1956
C +NTAG C C G+YG+A+ +C AC C C G C C+ G G
Sbjct: 1706 CQHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 1957 KCDRCAPDHWG--LNTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
+C+RCAP ++G G C PC+C + C G C ++CD C
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 110 bits (265), Expect = 8e-23
Identities = 63/208 (30%), Positives = 89/208 (42%), Gaps = 33/208 (15%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C CQP G +C CA G+YG P CKPC+C + C+ + G C +
Sbjct: 1285 CPCQPNVIGRQCTRCATGHYGFPR---------CKPCSCGRRL-------CEEMTGQC-R 1327
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG-----MADCDSTTGTCVCRPGVIG 1955
C T C +C + + C C C G M +CD +G C C+P + G
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMA-GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITG 1386
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
+CDRCA + C PCNC +E CD G C C + V G +C+ C G +
Sbjct: 1387 RQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSF 1443
Query: 2015 NY---TKDGCDHCNCNTGYSVGFMCNAT 2039
+ GC C C + V C+++
Sbjct: 1444 HLDPANLKGCTSCFC---FGVNNQCHSS 1468
Score = 108 bits (260), Expect = 3e-22
Identities = 99/404 (24%), Positives = 164/404 (40%), Gaps = 27/404 (6%)
Query: 1901 CVNNTAGAACNLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEK 1957
C AG +C C+PG+Y D +++ C C C+ C +G CV C+ GE
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEH 1714
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNG--QCRCAKGVTGKQCDQCAAG-F 2013
C+RC ++G C C C + +T C + G +C C G TG QC++CA G F
Sbjct: 1715 CERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF 1774
Query: 2014 WNYTKDG--CDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
N K G C C+CN+ +G TG C + E D P E C +C
Sbjct: 1775 GNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC-----INQEPKDSS-------PAEECDDC 1822
Query: 2072 DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDI 2131
DSC L+ + + L + + S +++ ++ Q + LR ++ ++ I
Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-I 1881
Query: 2132 GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVV 2191
S I+ LE +L + E + +A L + R + +E + V+
Sbjct: 1882 SNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVI 1941
Query: 2192 KHVADLATGLELSQQPKVDSALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNF 2251
++V + + Q+ A IRD + + + K A Q ++ N
Sbjct: 1942 RNV-HMLNRIRTWQKTHQGENNGLANSIRDSLNEYE--AKLSDLRARLQEAAAQAKQANG 1998
Query: 2252 FVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLA 2295
Q NE+A + R + SL + + D L T++A
Sbjct: 1999 LNQE-NERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIA 2041
Score = 107 bits (257), Expect = 7e-22
Identities = 57/174 (32%), Positives = 81/174 (46%), Gaps = 23/174 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C C Y+G +C C GYY Y C PCNC+ + C D SG C+ C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQ 579
G C++C GYY + C C C T S +T C +G +C+C + G QC++
Sbjct: 1711 AGEHCERCQEGYYGNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 1768
Query: 580 CSPGYYKYP-----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C+PGY+ P C C+C+ +G +GS G C K + +CD C
Sbjct: 1769 CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 104 bits (249), Expect = 7e-21
Identities = 57/173 (32%), Positives = 84/173 (48%), Gaps = 25/173 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNY 431
C C P + C C+ GY+ D+ C PC CN + + C G+C C++N
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
Query: 432 AGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQ 485
AG+ CE C++GYY C+ C C S + C GD C+CK+ Y+G C +C
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 486 AGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
GY+ P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 104 bits (249), Expect = 7e-21
Identities = 89/363 (24%), Positives = 160/363 (44%), Gaps = 24/363 (6%)
Query: 3309 RFGSRNVSRIEYAKLPGRQLEG-FDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
+FG S + + KLP L+ + +T +G ++F+ + KN F+A ++
Sbjct: 2932 QFGDIPTSHLLF-KLPQELLKPRSQFAVDMQTTSSRG-LVFHTGT---KN--SFMALYLS 2984
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPL 3427
+L + G+ I S ND WHTV +G G+L VD E S+ N+ +
Sbjct: 2985 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 3044
Query: 3428 SLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN-I 3486
S+ P Y G + + + N F+GCLK ++ + + ++ C+ +
Sbjct: 3045 SIRAPVYLGS--PPSGKPKSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 3099
Query: 3487 EDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK-DYMVLELL 3545
E G+YF + ++ L + +G E + +RPR+ TG+L+ + + ++ + L
Sbjct: 3100 EKGIYF----SEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 3155
Query: 3546 DSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFS-KPGIGA 3604
+V A++++G G + ++ K LCDG WH + D S G
Sbjct: 3156 AGKVTASMDSGAG--GTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIP 3213
Query: 3605 YTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRG-AHVG 3663
+ T L++GG + +R + + F GC+RNI V PV V + +G +
Sbjct: 3214 FPPASTQEPLHLGGAPANLTTLR-IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 3272
Query: 3664 VCP 3666
CP
Sbjct: 3273 GCP 3275
Score = 97.9 bits (233), Expect = 6e-19
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 40/203 (19%)
Query: 249 LNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDE 308
L + +C C G C C G+ +R + C PCNC+ H+ +C
Sbjct: 1649 LAVEICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------- 1697
Query: 309 KRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPH-- 366
+G G C+NCQHNT G +C +C+ Y YG C+ C C PH
Sbjct: 1698 -----------DGSGICVNCQHNTAGEHCERCQEGY---YGNAVH--GSCRACPC-PHTN 1740
Query: 367 -FSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHC 418
F+TG C G RC C+ + C CA GYF P +C+PC+CN NG G C
Sbjct: 1741 SFATG-CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-C 1798
Query: 419 TPTDGLCPCKYNYAGKSCEICED 441
P G C + E C+D
Sbjct: 1799 HPLTGDCINQEPKDSSPAEECDD 1821
Score = 95.5 bits (227), Expect = 3e-18
Identities = 56/174 (32%), Positives = 81/174 (46%), Gaps = 15/174 (8%)
Query: 566 CNCLTNFGGAQCDQCSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFD 618
C C + G C CSPGYY+ Y C+ CNC+ G D +G+C +C+ N
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTA 1711
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFA-GCGSVPAGEL-CQCKDRVQGRICNDCK 676
G C+ C+E +Y C P T SFA GC V G++ C CK G C C
Sbjct: 1712 GEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC-VVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
P Y+ + C+ C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 1821
Score = 93.5 bits (222), Expect = 1e-17
Identities = 74/261 (28%), Positives = 110/261 (42%), Gaps = 26/261 (9%)
Query: 1947 CVCRPGVIGEKCDRCAP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
C C P G+ C C+P DH GL TG C PCNC S QC D +G C C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN--GHSNQCQDGSGICVNCQHNT 1710
Query: 2002 TGKQCDQCAAGFW-NYTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCDRCP 2057
G+ C++C G++ N C C C S C G +C C G G +C+RC
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 2058 ERWVLIPQE---GCLECDSCTDALIFSVEDLSALLAN-ETMDFK-----DKADSFFTTQR 2108
+ PQ+ C C ++ + S L+ N E D D DS T
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMT-L 1829
Query: 2109 LNYISNQTELLRPKVAQLKTVDIGE-VTSSIKTLETSAKNL---LRSAEFAATDSDKQIS 2164
LN ++ E LR +QL+ + + ++ +ET AK+L L + A ++ +I
Sbjct: 1830 LNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIE 1889
Query: 2165 RAAKLAEDAERTLAAVRESAR 2185
+ D + ++E A+
Sbjct: 1890 GLERELTDLNQEFETLQEKAQ 1910
Score = 91.9 bits (218), Expect = 4e-17
Identities = 52/173 (30%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 424 LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
+C C YAG SC+ C GY Y+ C C CN S C +G C C+
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHN 1709
Query: 476 YSGRTCNQCQAGYYN---YPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQC 530
+G C +CQ GYY + +C+ C C + + + C G +C CKAG+ G +C++C
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC---NCLTNFGGAQCDQC 580
GY+ C PC+C+ G + G C + +CD C
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 84.2 bits (199), Expect = 8e-15
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 37/235 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNG---HSDQCDVNTGICLNCADNTIGDH 1792
C C G C+ C G Y P C C C+ + C TG C C G
Sbjct: 509 CLCRPGVEGPRCDTCRSGFYSFP--ICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQR 565
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSE--NGSLISCNCQPGYGGA 1850
C+ C+SG A P+ + + +CD + N +L C C+ G
Sbjct: 566 CDRCLSG----------------AYDFPHCQGSSS-ACDPAGTINSNLGYCQCKLHVEGP 608
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C C Y+ + D + +G C C C G C +GDC C ++ G +C
Sbjct: 609 TCSRCKLLYWNL--DKENPSG--CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSC 663
Query: 1911 NLCAPGFYGDAIFSKN---CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDR 1960
+ C G++ A+ N C C CD G C +G C CR V+G+ C R
Sbjct: 664 DTCEDGYF--ALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716
Score = 65.7 bits (153), Expect = 3e-09
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 1687 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 1733
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + +NG G +C +C+ G C +C P Y +G
Sbjct: 1734 CPC----------PHTNSFATGCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 1776
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 1777 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 1825
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/157 (28%), Positives = 57/157 (36%), Gaps = 31/157 (19%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC T PQC C E + CE CNC T PE D
Sbjct: 1326 CRCPPRTVRPQCEVC----ETHSFSFH---PMAGCEGCNCSRRGTIEAAMPECD------ 1372
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD-PHFSTGNC 372
G+C C+ G C++C +YR C PC C+ G C
Sbjct: 1373 ------RDSGQC-RCKPRITGRQCDRCASGFYR--------FPECVPCNCNRDGTEPGVC 1417
Query: 373 EEESGRCECRPEFQPPDCSSCAYGYF--DYPNCKPCT 407
+ +G C C+ + +C+ C G F D N K CT
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCT 1454
Score = 54.4 bits (125), Expect = 7e-06
Identities = 45/190 (23%), Positives = 70/190 (36%), Gaps = 27/190 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD------VNTGICLNCADNT 1788
+C+C G C++C G Y P C G S CD N G C C +
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFP-------HCQGSSSACDPAGTINSNLGYC-QCKLHV 605
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C Y + P C C C + + + + + + C+C+ G
Sbjct: 606 EGPTCSRCKLLY-WNLDKENPSGCSECKC---HKAGTVSGTGECRQGDG--DCHCKSHVG 659
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
G C+ C GY+ + + + G C+ C C +I C +G C +C + G
Sbjct: 660 GDSCDTCEDGYFALEKSN--YFG--CQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGK 712
Query: 1909 ACNLCAPGFY 1918
C +Y
Sbjct: 713 VCQRPENNYY 722
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCN--GHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P F C PC CN G C TG C+N D++
Sbjct: 1755 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 1814
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 1815 PAEECDDCDS 1824
Score = 50.8 bits (116), Expect = 9e-05
Identities = 60/292 (20%), Positives = 118/292 (40%), Gaps = 30/292 (10%)
Query: 2725 RVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEK 2784
R+ + D +W+ V+ G + +L + D + ++E LPG+ TI +
Sbjct: 3000 RIKSKEKCNDGKWHTVVFGHDGEKGRLVV--------DGLRAREGSLPGNSTI----SIR 3047
Query: 2785 SKLYVGGVPSDAKLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQ 2844
+ +Y+G PS K + + +F G ++ + P+ + ++ + S
Sbjct: 3048 APVYLGSPPS-GKPKSLPTNSFVGCLKNFQLDSKPL----YTPSSSFG-------VSSCL 3095
Query: 2845 SGPQE---YRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
GP E Y + G+ +A L P+ V LI++ + G + ++
Sbjct: 3096 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 3155
Query: 2902 DGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSA 2961
G+V + G V ++ DG+WH + L +D + P
Sbjct: 3156 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 3215
Query: 2962 DIPSLDTMNFGG--NNKGILQVPD-RGFDGCMRQISINGVNLDLSENLESIG 3010
+ + ++ GG N L++P + F GC+R I +N + + ++E LE G
Sbjct: 3216 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 3267
Score = 50.0 bits (114), Expect = 2e-04
Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 9/309 (2%)
Query: 2866 LTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
L P+S Q + +T + GL++ G F +L + GR L +LG + + +
Sbjct: 2950 LKPRS-QFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGR--LVFALGTDGKKLRIKSKEK 3006
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKG-ILQVPDR 2984
NDGKWH + K L VD + S ++ I + G G +P
Sbjct: 3007 CNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTN 3066
Query: 2985 GFDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTL 3044
F GC++ ++ L + + G + F+ ++ P+ L
Sbjct: 3067 SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKL 3126
Query: 3045 KFKTAKPNGL--LFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-TGLNTYNDSQW 3101
F + +P L + +++ + + V + + T + D QW
Sbjct: 3127 VF-SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQW 3185
Query: 3102 HVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFT 3161
H + VT L L +D ++ P P L +GG P + + + F
Sbjct: 3186 HSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGA-PANLTTLRIPVWKSFF 3244
Query: 3162 GCIGDATIN 3170
GC+ + +N
Sbjct: 3245 GCLRNIHVN 3253
Score = 49.2 bits (112), Expect = 3e-04
Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 27/111 (24%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C+ T E A P + + CRC+ G QC++C SGF +R + C P
Sbjct: 1356 CNCSRRG-TIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE------CVP 1404
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
CNC+ TE P + + G G CL C+ N EG CN CR
Sbjct: 1405 CNCNRDGTE----PGVCD-----------PGTGACL-CKENVEGTECNVCR 1439
>AY327115-1|AAQ72570.1| 3333|Homo sapiens laminin alpha 3 splice
variant b1 protein.
Length = 3333
Score = 867 bits (2145), Expect = 0.0
Identities = 529/1618 (32%), Positives = 766/1618 (47%), Gaps = 151/1618 (9%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE--EESGRCECRPEFQPPDCSSCAYGYFD 399
PT R Y ++ + C C+ H N E+ RCEC+ C C GY +
Sbjct: 280 PTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY-N 338
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSV 459
+P + C C C + +A +C YY P+ + + +
Sbjct: 339 QRRWRPAAWE----QSHECEA----CNC-HGHAS-NC------YYDPDVERQQASLNTQG 382
Query: 460 SYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYN---YPT-----CKPCNCDTSGTEPSICD 510
Y G C C+ +G C QC GYY P C PC+CD + C+
Sbjct: 383 IYAGG---GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CE 437
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP----------------CNCDPTG 554
SG+C CK F G C++C GYY P C+C+ G
Sbjct: 438 QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEG 497
Query: 555 STSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHC 613
C A G+C C G +CD C G+Y +P C +C C GS C G C C
Sbjct: 498 VLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCEC 557
Query: 614 KSNFDGAKCDTCREQFYNYPACEECN--CDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
+ G +CD C Y++P C+ + CDP G S G CQCK V+G
Sbjct: 558 RPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLG--------YCQCKLHVEGPT 609
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG 731
C+ CK LYWNL + NP GC +C C+ AGT++ G C G C CK HVG CD C DG
Sbjct: 610 CSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDG 669
Query: 732 FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQF 791
++ L+ ++ FGC C CDIGG++ + C +G C C V G+ C +P +YFP LH
Sbjct: 670 YFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHM 729
Query: 792 QYEVEDGVTQSG-PVRYRNSEEVFPEYSWKGYVVFSLLQNEVINIIQITKSS--LYRMVL 848
+YE+EDG T +G +R+ FPE+SW+GY + +QN+V + + KSS L+R++L
Sbjct: 730 KYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVIL 789
Query: 849 KYANPLRDPVVANIVITPESVVDIQQKFNVYLRPTVLPQLVTVAGDKGVTPAPFVMNPGN 908
+Y NP + V +I I P S Q K ++L P+ P VTV G+ G PF + PG
Sbjct: 790 RYVNPGTEAVSGHITIYP-SWGAAQSKEIIFL-PSKEPAFVTVPGN-GFAD-PFSITPGI 845
Query: 909 WTVTIKTNKEIMIDYFVLIPEAYYEATILTKMVDKPCIVGDKKLCRQFAYPSLSGKSTAD 968
W IK + +++DY VL+P YYEA++L V +PC Y L T
Sbjct: 846 WVACIKA-EGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLP--VTRF 902
Query: 969 VTSLVTSVDSFIDD----PVQLSE-LKVEPNTIPILRTTLQYNMRIEKP--GQYVLLVEY 1021
+L F+ D PV + + P + + ++ ++R+ P G YV++VEY
Sbjct: 903 PCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEY 962
Query: 1022 VTPAARNQDLNTGNSTYSSVVKTPVTIKFQSGPDDQHLVETDGIINFNDCPYTAPCRQVM 1081
T AA+ ++ + SV+ G +N C Y+ CR +
Sbjct: 963 STEAAQLFVVDVNVKSSGSVLA--------------------GQVNIYSCNYSVLCRSAV 1002
Query: 1082 VDDYSRIQFVTVTDPNNVVFLLDQPDTEAAIKSVVAIPQAEWHLDYLTPRPYCLRRNGRC 1141
+D SRI + ++ L + V IP E+ +Y+ P+ +C+ GR
Sbjct: 1003 IDHMSRIAMYELLADADIQ--LKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRF 1060
Query: 1142 DPAVFNAVVDAKKVE-----FESGTGGDRETRPQILNNSTTV---VYLPTQSEPVILEGK 1193
V A + + +G PQ + S V V L V L G+
Sbjct: 1061 VNQSATCVSLAHETPPTALILDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGR 1120
Query: 1194 VSAPGEYLFMVHYYQPDHPESTMEVTVNTDGQKQETNLPIQHCPSNSGCRALLRKPDTST 1253
V G Y+F++H+YQ HP +V+V+ G + + CP GCR +
Sbjct: 1121 VPHLGRYVFVIHFYQAAHPTFPAQVSVD-GGWPRAGSFHASFCPHVLGCRDQVIAEGQIE 1179
Query: 1254 SFLVNENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYY 1313
+ K K + L VLV+ A ++ +L + + +D + EFI C ++Y
Sbjct: 1180 FDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKS-MDKSLEFITNCGKNSFY 1238
Query: 1314 ISPNETG-LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+ P C+ + S+ + Y+ GA PC C G+T C+ GGQCPC+PNVIGR C+
Sbjct: 1239 LDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTR 1298
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
C TG+YGFP C+PC C +C++ G C CP C+ C+ ++F+F GC+ CN
Sbjct: 1299 CATGHYGFPRCKPCSC-GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCN 1357
Query: 1432 CNPLGVVGNQL-QCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVC 1490
C+ G + + +C+ DSG+C C+ + GR CD C G Y FP+C C CNR GT VC
Sbjct: 1358 CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVC 1417
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDE 1550
D T C CK NV G C+ C+E F+L N GCT CFCFG +C SS+ +
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVD 1477
Query: 1551 MVDWYPVDVLINNTIELYPHEDVPELTN--VTVLTVGLNDGVTNGKVAYFGAPEYYLGKR 1608
M+ W+ +E D+P N + L + A + AP YLG +
Sbjct: 1478 MLGWH---------LETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDK 1528
Query: 1609 LTSYGGYLTYTV-HYTTRGDGDAV-AAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLS 1666
++SYGGYLTY + GD + PDV + G + +++ P V +
Sbjct: 1529 VSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVV 1588
Query: 1667 EEEFSTLDG-APVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDEL 1725
E F APV+R++ M L ++ + I+ Y+ + +LS V LE D G
Sbjct: 1589 EGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSG--- 1645
Query: 1726 VVRRATSVEECQCPRAYRGLSCEQCAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGIC 1781
R A +VE C CP AY G SC+ C+ G+YR L +G CVPC CNGHS+QC +GIC
Sbjct: 1646 --RIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGIC 1703
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
+NC NT G+HCE C GY+G+A G+ R ACP P+ +N+FA C + NG + C
Sbjct: 1704 VNCQHNTAGEHCERCQEGYYGNAVHGSCR-----ACPCPH-TNSFATGCVV--NGGDVRC 1755
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
+C+ GY G +CE CA GY+G P+ G C+PC+C+ N GSC + GDC+
Sbjct: 1756 SCKAGYTGTQCERCAPGYFGNPQ----KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 1806
Score = 626 bits (1547), Expect = e-178
Identities = 278/630 (44%), Positives = 377/630 (59%), Gaps = 42/630 (6%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CD C++ + K HP A+D WWQSPPLS G +YN VNLT+DLGQ FHVAY+ +K
Sbjct: 102 CDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFA 161
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G T+ PWQYF+ S DC + FG+E+ +T+DD V+C TEYS+I
Sbjct: 162 NSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRI 221
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GE+ +SL+N RP + + S L+E+T+ATN+RLR LRT LLGHL+S A++DPT
Sbjct: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGG+C+CNGHA+ C +P + C CQH+TCG C++CC+G+
Sbjct: 282 VTRRYYYSIKDISIGGQCVCNGHAEVCNINNPE---KLFRCECQHHTCGETCDRCCTGYN 338
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q++WR + CE CNCH H + C YDP+++ ++ SL+ G Y GGG C+NCQHNT
Sbjct: 339 QRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTA 398
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C YYRPYG D D C PC CDP + G CE+ SGRC C+P F +C C
Sbjct: 399 GVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRCHCKPNFHGDNCEKC 457
Query: 394 AYGYFDYPNC---------------------KPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
A GY+++P C K C CNL G E C G C C+
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVE 516
Query: 433 GKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
G C+ C G+YS P C+ C C+ +GS C +TG C C+ +G+ C++C +G Y++
Sbjct: 517 GPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDF 576
Query: 492 PTCKPCN--CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
P C+ + CD +GT + G C CK GP C +C Y+ C C
Sbjct: 577 PHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECK 632
Query: 550 CDPTGSTSTS--C-SADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI 601
C G+ S + C DG C+C ++ GG CD C GY+ Y C C CD+ G++
Sbjct: 633 CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGAL 692
Query: 602 GSTCD-DNGLCHCKSNFDGAKCDTCREQFY 630
S C +G+C C+ + G C +Y
Sbjct: 693 SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 205 bits (501), Expect = 2e-51
Identities = 260/1269 (20%), Positives = 504/1269 (39%), Gaps = 108/1269 (8%)
Query: 1901 CVNNTAGAACNLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEK 1957
C AG +C C+PG+Y D +++ C C C+ C +G CV C+ GE
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEH 1714
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNG--QCRCAKGVTGKQCDQCAAGFW 2014
C+RC ++G C C C + +T C + G +C C G TG QC++CA G++
Sbjct: 1715 CERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF 1774
Query: 2015 -NYTKDG--CDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
N K G C C+CN+ +G TG C + E D P E C +C
Sbjct: 1775 GNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC-----INQEPKDSSPA-------EECDDC 1822
Query: 2072 DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDI 2131
DSC L+ + + L + + S +++ ++ Q + LR ++ ++ I
Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-I 1881
Query: 2132 GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVV 2191
S I+ LE +L + E + +A L + R + +E + V+
Sbjct: 1882 SNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVI 1941
Query: 2192 KHVADL-----ATGLELSQQPKVDSAL--TEARQIRDDIADKDLVPKKQQAEAVFLNTTT 2244
++V L T E + P D + EA+++ ++ +++ ++AEA +
Sbjct: 1942 RNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQL 2001
Query: 2245 QIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEE 2304
+ R+ + + + ++ S+ ++ E + KL D+ A A A
Sbjct: 2002 LLNRIRTWQKTHQGENNGLAN-------SIRDSLNEYEAKLSDLRARLQEAAAQAKQANG 2054
Query: 2305 LNTKNRLSKFGNKVNSVTKLNTAAMGDLIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXX 2364
LN +N + G V ++N+ D ++
Sbjct: 2055 LNQENERA-LGAIQRQVKEINSL-QSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 2112
Query: 2365 XXXXXXXXXXXXXTGELPQFEHLTS---EATHHATMLRRRADSLRELAERENNNSRTQHX 2421
EL + TS EA HA L+ A L E+ + + +
Sbjct: 2113 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 2172
Query: 2422 XXXXXXXXXXXQEINXXXXXXXXXXXXXXNV--TKLNRILDERVRPARERSSSLLADATK 2479
I + T + L + + S LL +A
Sbjct: 2173 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 2232
Query: 2480 AQHAVDQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRV 2538
Q + Q++ P L ++ L + D + ++ + A V
Sbjct: 2233 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 2292
Query: 2539 NATIGTTFSVMSHLGPELATSKDWAQTLPKLADEG-QKMTSNVESHLKNINDMEPQISSS 2597
T V+ L P + T + +E +K ++ ++ + + + P +
Sbjct: 2293 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 2352
Query: 2598 YHTVKMXXXXXXXXXXXXXXKLQKLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVD 2657
++ + ++++L++QAR A+++ V + F+ S ++ RLP+ ++
Sbjct: 2353 IESINQQLLPLGNISD----NMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLE 2408
Query: 2658 EMSTSTHVSAYFR---TKEKDG----FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVV 2710
++ T +S + + ++E G F++YLGN + S DY+ + + +G V
Sbjct: 2409 DLKGYTSLSLFLQRPNSRENGGTENMFVMYLGN-------KDASRDYIGMAVVDGQLTCV 2461
Query: 2711 MDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA 2769
++GD A + +D+++ + + ++DR+ +R+ R + G + +
Sbjct: 2462 YNLGDRE------AELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETP 2515
Query: 2770 ---DLPGH--HTIFNLDKEKSKLYVGGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLW 2823
D+ G +T+ NLD E YVGG P D KL +SFP ++G IE + + + L+
Sbjct: 2516 GVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLY 2575
Query: 2824 NFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAP 2882
NF L + + Y F+G GYA + + + P Q + +T
Sbjct: 2576 NFKKTFNLNTTEVEPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVD 2631
Query: 2883 NGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAK 2942
GL++ G F SL ++DG++ ++ L N+E G A N+G+ H + + +
Sbjct: 2632 RGLLFFAENGDRFISLNIEDGKLMVRYKL-NSELPKERGVGDAINNGRDHSIQIKIGKLQ 2690
Query: 2943 CSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGI---LQVPDRGFDGCMRQISINGVN 2999
+ ++ +V ++ ++ T GG I + F GCM+ +
Sbjct: 2691 KRMWINVDV---QNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGV 2747
Query: 3000 LDLSENLESIGMAYGC----QFASLVSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPN 3052
+ L+ +++G+ C + SF+ L F D+ +++ Q + F+T +P+
Sbjct: 2748 VRLN---DTVGVTKKCSEDWKLVRSASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPS 2803
Query: 3053 GLLFVYVSRTQTAIMPDSISLSLVNG--KLVVVSQREQLDTGLNTYNDSQWHVLTVTHNT 3110
G+L + + T+ ++ ++L +G +L + TY D H ++V +
Sbjct: 2804 GILLDHQTWTR------NLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDN 2857
Query: 3111 SALKLVVDD 3119
S L+L++DD
Sbjct: 2858 SGLRLLIDD 2866
Score = 171 bits (416), Expect = 4e-41
Identities = 115/356 (32%), Positives = 161/356 (45%), Gaps = 53/356 (14%)
Query: 1738 CPRAYRGLSCEQCAEGHYR-------LPSGFCVPCQCNG-HSDQCDVNTGICLNCADNTI 1789
C G++CEQCA+G+YR P G C+PC C+ H+D C+ +G C +C N
Sbjct: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-CIPCSCDPEHADGCEQGSGRC-HCKPNFH 450
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS-----CDLSENGSLIS---- 1840
GD+CE C GY+ P I P+ PS+ ++ CD + G L
Sbjct: 451 GDNCEKCAIGYYN-----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 505
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD 1897
C C+PG G RC+ C +G+Y P C+ C CS + Q P C S+ G
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP---------ICQACWCSALGSYQMP--CSSVTGQ 554
Query: 1898 CLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
C +C G C+ C G Y + +AC D G + S G C C+ V G
Sbjct: 555 C-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC--DPAGTIN--SNLGYCQCKLHVEGPT 609
Query: 1958 CDRCAPDHWGLN--TGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAG 2012
C RC +W L+ GC+ C C G S + +C +G C C V G CD C G
Sbjct: 610 CSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDG 669
Query: 2013 FWNYTKD---GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIP 2064
++ K GC C C+ G ++ MC+ +G C+C V+G+ C R PE P
Sbjct: 670 YFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR-PENNYYFP 724
Score = 169 bits (410), Expect = 2e-40
Identities = 118/388 (30%), Positives = 161/388 (41%), Gaps = 71/388 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRL---PSGF-----CVPCQCNGHSDQC-----------DV 1776
C+C G +C++C G+ + P+ + C C C+GH+ C +
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 1777 NT-------GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICACPMPYPSNNFA 1827
NT G+C+NC NT G +CE C GY+ V P C+ C+C +
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH------ 432
Query: 1828 LSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-------------EDTDLHTGDYC 1874
D E GS C+C+P + G CE CA GYY P D GD
Sbjct: 433 --ADGCEQGSG-RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI- 488
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDE 1934
K C+C N+ P CD+ +G CL C G C+ C GFY I C AC C
Sbjct: 489 KGCDC--NLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSA 540
Query: 1935 FG--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDN 1992
G C S TG C CRPGV G++CDRC + G + C A + +
Sbjct: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAG---TINSNL 596
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV---GFMCNATGQCECLP 2046
G C+C V G C +C +WN K+ GC C C+ +V G G C C
Sbjct: 597 GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKS 656
Query: 2047 GVIGEKCDRCPERWVLIPQEGCLECDSC 2074
V G+ CD C + + + + C C
Sbjct: 657 HVGGDSCDTCEDGYFALEKSNYFGCQGC 684
Score = 139 bits (337), Expect = 2e-31
Identities = 97/341 (28%), Positives = 144/341 (42%), Gaps = 42/341 (12%)
Query: 231 CMCNG-HADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C C+ HAD CE +G C C+ N G C KC G+ + + R
Sbjct: 426 CSCDPEHADGCEQG--SGR-----CHCKPNFHGDNCEKCAIGYYNFPFCL-----RIPIF 473
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
P + + D + + L + + G+CL C+ EG C+ CR +Y
Sbjct: 474 PVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFY---- 528
Query: 350 KRWDELDVCQPCQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCT- 407
+CQ C C S C +G+CECRP C C G +D+P+C+ +
Sbjct: 529 ----SFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSS 584
Query: 408 -CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE------CKNCECNTVGSVS 460
C+ GT + G C CK + G +C C+ Y++ + C C+C+ G+VS
Sbjct: 585 ACDPAGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVS 640
Query: 461 YV--CDKLTGDCTCKSKYSGRTCNQCQAGYY-----NYPTCKPCNCDTSGTEPSICDDVS 513
C + GDC CKS G +C+ C+ GY+ NY C+ C CD G S+C S
Sbjct: 641 GTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPS 700
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
G C C+ G C + + YY L + + P G
Sbjct: 701 GVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
Score = 136 bits (330), Expect = 1e-30
Identities = 102/347 (29%), Positives = 147/347 (42%), Gaps = 54/347 (15%)
Query: 1765 CQCNGHSDQCDVNTGICL---NCADNTIGDHCEFCMSGYH----GDATVGTPRDCLICAC 1817
C CNGH++ C++N L C +T G+ C+ C +GY+ A +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1818 PMPYPSNNF----------ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTD 1867
+ SN + +L+ G + NCQ G CE CA GYY P
Sbjct: 359 -HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVP 416
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG------DA 1921
+ D C PC+C +P+ C+ +G C C N G C CA G+Y
Sbjct: 417 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIP 471
Query: 1922 IF-----------SKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
IF + + C C+ G+ CD+ G C+CRPGV G +CD C +
Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGPRCDTCRSGFYSF 530
Query: 1969 NTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN 2027
C C C + S C GQC C GVTG++CD+C +G +++ C+
Sbjct: 531 PI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587
Query: 2028 TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQE---GCLEC 2071
G + + G C+C V G C RC + + +E GC EC
Sbjct: 588 ---PAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSEC 631
Score = 127 bits (307), Expect = 7e-28
Identities = 72/206 (34%), Positives = 93/206 (45%), Gaps = 21/206 (10%)
Query: 1876 PCNC--SGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICD 1933
PC C +G P C G C C N G C CA G YG F + C C C
Sbjct: 1265 PCECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYG---FPR-CKPCSC- 1314
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG----IASESTQCD 1989
G C+ TG C C P + +C+ C + + GC CNC I + +CD
Sbjct: 1315 --GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECD 1372
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN-TGYSVGFMCNATGQCECLPGV 2048
D+GQCRC +TG+QCD+CA+GF+ + + C CNCN G G TG C C V
Sbjct: 1373 RDSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
Query: 2049 IGEKCDRCPERWVLIPQEGCLECDSC 2074
G +C+ C E + C SC
Sbjct: 1431 EGTECNVCREGSFHLDPANLKGCTSC 1456
Score = 118 bits (283), Expect = 5e-25
Identities = 66/202 (32%), Positives = 85/202 (42%), Gaps = 25/202 (12%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCEC 381
GG+C CQ N G C +C +Y C+PC C CEE +G+C C
Sbjct: 1282 GGQC-PCQPNVIGRQCTRCATGHY--------GFPRCKPCSCGRRL----CEEMTGQCRC 1328
Query: 382 RPEFQPPDCSSC---AYGYFDYPNCKPCTCNLNGT---EGEHCTPTDGLCPCKYNYAGKS 435
P P C C ++ + C+ C C+ GT C G C CK G+
Sbjct: 1329 PPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQ 1388
Query: 436 CEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC 494
C+ C G+Y PEC C CN G+ VCD TG C CK G CN C+ G ++
Sbjct: 1389 CDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFH---L 1445
Query: 495 KPCNCDTSGTEPSICDDVSGQC 516
P N G C V+ QC
Sbjct: 1446 DPAN--LKGCTSCFCFGVNNQC 1465
Score = 114 bits (275), Expect = 5e-24
Identities = 61/178 (34%), Positives = 83/178 (46%), Gaps = 18/178 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C P Y G C+ C+ GYY + L+TG C PCNC+G+ N C +G C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVN 1705
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTG--TCVCRPGVIGE 1956
C +NTAG C C G+YG+A+ +C AC C C G C C+ G G
Sbjct: 1706 CQHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 1957 KCDRCAPDHWG--LNTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
+C+RCAP ++G G C PC+C + C G C ++CD C
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 110 bits (265), Expect = 8e-23
Identities = 63/208 (30%), Positives = 89/208 (42%), Gaps = 33/208 (15%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C CQP G +C CA G+YG P CKPC+C + C+ + G C +
Sbjct: 1285 CPCQPNVIGRQCTRCATGHYGFPR---------CKPCSCGRRL-------CEEMTGQC-R 1327
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG-----MADCDSTTGTCVCRPGVIG 1955
C T C +C + + C C C G M +CD +G C C+P + G
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMA-GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITG 1386
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
+CDRCA + C PCNC +E CD G C C + V G +C+ C G +
Sbjct: 1387 RQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSF 1443
Query: 2015 NY---TKDGCDHCNCNTGYSVGFMCNAT 2039
+ GC C C + V C+++
Sbjct: 1444 HLDPANLKGCTSCFC---FGVNNQCHSS 1468
Score = 107 bits (257), Expect = 7e-22
Identities = 57/174 (32%), Positives = 81/174 (46%), Gaps = 23/174 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C C Y+G +C C GYY Y C PCNC+ + C D SG C+ C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQ 579
G C++C GYY + C C C T S +T C +G +C+C + G QC++
Sbjct: 1711 AGEHCERCQEGYYGNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 1768
Query: 580 CSPGYYKYP-----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C+PGY+ P C C+C+ +G +GS G C K + +CD C
Sbjct: 1769 CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 104 bits (249), Expect = 7e-21
Identities = 57/173 (32%), Positives = 84/173 (48%), Gaps = 25/173 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNY 431
C C P + C C+ GY+ D+ C PC CN + + C G+C C++N
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
Query: 432 AGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQ 485
AG+ CE C++GYY C+ C C S + C GD C+CK+ Y+G C +C
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 486 AGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
GY+ P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 104 bits (249), Expect = 7e-21
Identities = 89/363 (24%), Positives = 160/363 (44%), Gaps = 24/363 (6%)
Query: 3309 RFGSRNVSRIEYAKLPGRQLEG-FDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
+FG S + + KLP L+ + +T +G ++F+ + KN F+A ++
Sbjct: 2988 QFGDIPTSHLLF-KLPQELLKPRSQFAVDMQTTSSRG-LVFHTGT---KN--SFMALYLS 3040
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPL 3427
+L + G+ I S ND WHTV +G G+L VD E S+ N+ +
Sbjct: 3041 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 3100
Query: 3428 SLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN-I 3486
S+ P Y G + + + N F+GCLK ++ + + ++ C+ +
Sbjct: 3101 SIRAPVYLGS--PPSGKPKSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 3155
Query: 3487 EDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK-DYMVLELL 3545
E G+YF + ++ L + +G E + +RPR+ TG+L+ + + ++ + L
Sbjct: 3156 EKGIYF----SEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 3211
Query: 3546 DSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFS-KPGIGA 3604
+V A++++G G + ++ K LCDG WH + D S G
Sbjct: 3212 AGKVTASMDSGAG--GTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIP 3269
Query: 3605 YTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRG-AHVG 3663
+ T L++GG + +R + + F GC+RNI V PV V + +G +
Sbjct: 3270 FPPASTQEPLHLGGAPANLTTLR-IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 3328
Query: 3664 VCP 3666
CP
Sbjct: 3329 GCP 3331
Score = 97.9 bits (233), Expect = 6e-19
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 40/203 (19%)
Query: 249 LNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDE 308
L + +C C G C C G+ +R + C PCNC+ H+ +C
Sbjct: 1649 LAVEICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------- 1697
Query: 309 KRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPH-- 366
+G G C+NCQHNT G +C +C+ Y YG C+ C C PH
Sbjct: 1698 -----------DGSGICVNCQHNTAGEHCERCQEGY---YGNAVH--GSCRACPC-PHTN 1740
Query: 367 -FSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHC 418
F+TG C G RC C+ + C CA GYF P +C+PC+CN NG G C
Sbjct: 1741 SFATG-CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-C 1798
Query: 419 TPTDGLCPCKYNYAGKSCEICED 441
P G C + E C+D
Sbjct: 1799 HPLTGDCINQEPKDSSPAEECDD 1821
Score = 95.5 bits (227), Expect = 3e-18
Identities = 56/174 (32%), Positives = 81/174 (46%), Gaps = 15/174 (8%)
Query: 566 CNCLTNFGGAQCDQCSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFD 618
C C + G C CSPGYY+ Y C+ CNC+ G D +G+C +C+ N
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTA 1711
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFA-GCGSVPAGEL-CQCKDRVQGRICNDCK 676
G C+ C+E +Y C P T SFA GC V G++ C CK G C C
Sbjct: 1712 GEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC-VVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
P Y+ + C+ C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 1821
Score = 93.5 bits (222), Expect = 1e-17
Identities = 74/261 (28%), Positives = 110/261 (42%), Gaps = 26/261 (9%)
Query: 1947 CVCRPGVIGEKCDRCAP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
C C P G+ C C+P DH GL TG C PCNC S QC D +G C C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN--GHSNQCQDGSGICVNCQHNT 1710
Query: 2002 TGKQCDQCAAGFW-NYTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCDRCP 2057
G+ C++C G++ N C C C S C G +C C G G +C+RC
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 2058 ERWVLIPQE---GCLECDSCTDALIFSVEDLSALLAN-ETMDFK-----DKADSFFTTQR 2108
+ PQ+ C C ++ + S L+ N E D D DS T
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMT-L 1829
Query: 2109 LNYISNQTELLRPKVAQLKTVDIGE-VTSSIKTLETSAKNL---LRSAEFAATDSDKQIS 2164
LN ++ E LR +QL+ + + ++ +ET AK+L L + A ++ +I
Sbjct: 1830 LNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIE 1889
Query: 2165 RAAKLAEDAERTLAAVRESAR 2185
+ D + ++E A+
Sbjct: 1890 GLERELTDLNQEFETLQEKAQ 1910
Score = 91.9 bits (218), Expect = 4e-17
Identities = 52/173 (30%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 424 LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
+C C YAG SC+ C GY Y+ C C CN S C +G C C+
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHN 1709
Query: 476 YSGRTCNQCQAGYYN---YPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQC 530
+G C +CQ GYY + +C+ C C + + + C G +C CKAG+ G +C++C
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC---NCLTNFGGAQCDQC 580
GY+ C PC+C+ G + G C + +CD C
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 84.2 bits (199), Expect = 8e-15
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 37/235 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNG---HSDQCDVNTGICLNCADNTIGDH 1792
C C G C+ C G Y P C C C+ + C TG C C G
Sbjct: 509 CLCRPGVEGPRCDTCRSGFYSFP--ICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQR 565
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSE--NGSLISCNCQPGYGGA 1850
C+ C+SG A P+ + + +CD + N +L C C+ G
Sbjct: 566 CDRCLSG----------------AYDFPHCQGSSS-ACDPAGTINSNLGYCQCKLHVEGP 608
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C C Y+ + D + +G C C C G C +GDC C ++ G +C
Sbjct: 609 TCSRCKLLYWNL--DKENPSG--CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSC 663
Query: 1911 NLCAPGFYGDAIFSKN---CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDR 1960
+ C G++ A+ N C C CD G C +G C CR V+G+ C R
Sbjct: 664 DTCEDGYF--ALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716
Score = 65.7 bits (153), Expect = 3e-09
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 1687 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 1733
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + +NG G +C +C+ G C +C P Y +G
Sbjct: 1734 CPC----------PHTNSFATGCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 1776
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 1777 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 1825
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/157 (28%), Positives = 57/157 (36%), Gaps = 31/157 (19%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC T PQC C E + CE CNC T PE D
Sbjct: 1326 CRCPPRTVRPQCEVC----ETHSFSFH---PMAGCEGCNCSRRGTIEAAMPECD------ 1372
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD-PHFSTGNC 372
G+C C+ G C++C +YR C PC C+ G C
Sbjct: 1373 ------RDSGQC-RCKPRITGRQCDRCASGFYR--------FPECVPCNCNRDGTEPGVC 1417
Query: 373 EEESGRCECRPEFQPPDCSSCAYGYF--DYPNCKPCT 407
+ +G C C+ + +C+ C G F D N K CT
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCT 1454
Score = 54.4 bits (125), Expect = 7e-06
Identities = 45/190 (23%), Positives = 70/190 (36%), Gaps = 27/190 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD------VNTGICLNCADNT 1788
+C+C G C++C G Y P C G S CD N G C C +
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFP-------HCQGSSSACDPAGTINSNLGYC-QCKLHV 605
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C Y + P C C C + + + + + + C+C+ G
Sbjct: 606 EGPTCSRCKLLY-WNLDKENPSGCSECKC---HKAGTVSGTGECRQGDG--DCHCKSHVG 659
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
G C+ C GY+ + + + G C+ C C +I C +G C +C + G
Sbjct: 660 GDSCDTCEDGYFALEKSN--YFG--CQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGK 712
Query: 1909 ACNLCAPGFY 1918
C +Y
Sbjct: 713 VCQRPENNYY 722
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCN--GHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P F C PC CN G C TG C+N D++
Sbjct: 1755 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 1814
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 1815 PAEECDDCDS 1824
Score = 50.8 bits (116), Expect = 9e-05
Identities = 60/292 (20%), Positives = 118/292 (40%), Gaps = 30/292 (10%)
Query: 2725 RVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEK 2784
R+ + D +W+ V+ G + +L + D + ++E LPG+ TI +
Sbjct: 3056 RIKSKEKCNDGKWHTVVFGHDGEKGRLVV--------DGLRAREGSLPGNSTI----SIR 3103
Query: 2785 SKLYVGGVPSDAKLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQ 2844
+ +Y+G PS K + + +F G ++ + P+ + ++ + S
Sbjct: 3104 APVYLGSPPS-GKPKSLPTNSFVGCLKNFQLDSKPL----YTPSSSFG-------VSSCL 3151
Query: 2845 SGPQE---YRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
GP E Y + G+ +A L P+ V LI++ + G + ++
Sbjct: 3152 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 3211
Query: 2902 DGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSA 2961
G+V + G V ++ DG+WH + L +D + P
Sbjct: 3212 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 3271
Query: 2962 DIPSLDTMNFGG--NNKGILQVPD-RGFDGCMRQISINGVNLDLSENLESIG 3010
+ + ++ GG N L++P + F GC+R I +N + + ++E LE G
Sbjct: 3272 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 3323
Score = 50.0 bits (114), Expect = 2e-04
Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 9/309 (2%)
Query: 2866 LTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
L P+S Q + +T + GL++ G F +L + GR L +LG + + +
Sbjct: 3006 LKPRS-QFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGR--LVFALGTDGKKLRIKSKEK 3062
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKG-ILQVPDR 2984
NDGKWH + K L VD + S ++ I + G G +P
Sbjct: 3063 CNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTN 3122
Query: 2985 GFDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTL 3044
F GC++ ++ L + + G + F+ ++ P+ L
Sbjct: 3123 SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKL 3182
Query: 3045 KFKTAKPNGL--LFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-TGLNTYNDSQW 3101
F + +P L + +++ + + V + + T + D QW
Sbjct: 3183 VF-SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQW 3241
Query: 3102 HVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFT 3161
H + VT L L +D ++ P P L +GG P + + + F
Sbjct: 3242 HSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGA-PANLTTLRIPVWKSFF 3300
Query: 3162 GCIGDATIN 3170
GC+ + +N
Sbjct: 3301 GCLRNIHVN 3309
Score = 49.2 bits (112), Expect = 3e-04
Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 27/111 (24%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C+ T E A P + + CRC+ G QC++C SGF +R + C P
Sbjct: 1356 CNCSRRG-TIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE------CVP 1404
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
CNC+ TE P + + G G CL C+ N EG CN CR
Sbjct: 1405 CNCNRDGTE----PGVCD-----------PGTGACL-CKENVEGTECNVCR 1439
>AB107369-1|BAD13428.1| 3333|Homo sapiens laminin alpha 3b chain
protein.
Length = 3333
Score = 867 bits (2145), Expect = 0.0
Identities = 529/1618 (32%), Positives = 766/1618 (47%), Gaps = 151/1618 (9%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE--EESGRCECRPEFQPPDCSSCAYGYFD 399
PT R Y ++ + C C+ H N E+ RCEC+ C C GY +
Sbjct: 280 PTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY-N 338
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSV 459
+P + C C C + +A +C YY P+ + + +
Sbjct: 339 QRRWRPAAWE----QSHECEA----CNC-HGHAS-NC------YYDPDVERQQASLNTQG 382
Query: 460 SYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYN---YPT-----CKPCNCDTSGTEPSICD 510
Y G C C+ +G C QC GYY P C PC+CD + C+
Sbjct: 383 IYAGG---GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CE 437
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP----------------CNCDPTG 554
SG+C CK F G C++C GYY P C+C+ G
Sbjct: 438 QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEG 497
Query: 555 STSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHC 613
C A G+C C G +CD C G+Y +P C +C C GS C G C C
Sbjct: 498 VLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCEC 557
Query: 614 KSNFDGAKCDTCREQFYNYPACEECN--CDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
+ G +CD C Y++P C+ + CDP G S G CQCK V+G
Sbjct: 558 RPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLG--------YCQCKLHVEGPT 609
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG 731
C+ CK LYWNL + NP GC +C C+ AGT++ G C G C CK HVG CD C DG
Sbjct: 610 CSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDG 669
Query: 732 FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQF 791
++ L+ ++ FGC C CDIGG++ + C +G C C V G+ C +P +YFP LH
Sbjct: 670 YFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHM 729
Query: 792 QYEVEDGVTQSG-PVRYRNSEEVFPEYSWKGYVVFSLLQNEVINIIQITKSS--LYRMVL 848
+YE+EDG T +G +R+ FPE+SW+GY + +QN+V + + KSS L+R++L
Sbjct: 730 KYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVIL 789
Query: 849 KYANPLRDPVVANIVITPESVVDIQQKFNVYLRPTVLPQLVTVAGDKGVTPAPFVMNPGN 908
+Y NP + V +I I P S Q K ++L P+ P VTV G+ G PF + PG
Sbjct: 790 RYVNPGTEAVSGHITIYP-SWGAAQSKEIIFL-PSKEPAFVTVPGN-GFAD-PFSITPGI 845
Query: 909 WTVTIKTNKEIMIDYFVLIPEAYYEATILTKMVDKPCIVGDKKLCRQFAYPSLSGKSTAD 968
W IK + +++DY VL+P YYEA++L V +PC Y L T
Sbjct: 846 WVACIKA-EGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLP--VTRF 902
Query: 969 VTSLVTSVDSFIDD----PVQLSE-LKVEPNTIPILRTTLQYNMRIEKP--GQYVLLVEY 1021
+L F+ D PV + + P + + ++ ++R+ P G YV++VEY
Sbjct: 903 PCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEY 962
Query: 1022 VTPAARNQDLNTGNSTYSSVVKTPVTIKFQSGPDDQHLVETDGIINFNDCPYTAPCRQVM 1081
T AA+ ++ + SV+ G +N C Y+ CR +
Sbjct: 963 STEAAQLFVVDVNVKSSGSVLA--------------------GQVNIYSCNYSVLCRSAV 1002
Query: 1082 VDDYSRIQFVTVTDPNNVVFLLDQPDTEAAIKSVVAIPQAEWHLDYLTPRPYCLRRNGRC 1141
+D SRI + ++ L + V IP E+ +Y+ P+ +C+ GR
Sbjct: 1003 IDHMSRIAMYELLADADIQ--LKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRF 1060
Query: 1142 DPAVFNAVVDAKKVE-----FESGTGGDRETRPQILNNSTTV---VYLPTQSEPVILEGK 1193
V A + + +G PQ + S V V L V L G+
Sbjct: 1061 VNQSATCVSLAHETPPTALILDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGR 1120
Query: 1194 VSAPGEYLFMVHYYQPDHPESTMEVTVNTDGQKQETNLPIQHCPSNSGCRALLRKPDTST 1253
V G Y+F++H+YQ HP +V+V+ G + + CP GCR +
Sbjct: 1121 VPHLGRYVFVIHFYQAAHPTFPAQVSVD-GGWPRAGSFHASFCPHVLGCRDQVIAEGQIE 1179
Query: 1254 SFLVNENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYY 1313
+ K K + L VLV+ A ++ +L + + +D + EFI C ++Y
Sbjct: 1180 FDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKS-MDKSLEFITNCGKNSFY 1238
Query: 1314 ISPNETG-LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+ P C+ + S+ + Y+ GA PC C G+T C+ GGQCPC+PNVIGR C+
Sbjct: 1239 LDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTR 1298
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
C TG+YGFP C+PC C +C++ G C CP C+ C+ ++F+F GC+ CN
Sbjct: 1299 CATGHYGFPRCKPCSC-GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCN 1357
Query: 1432 CNPLGVVGNQL-QCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVC 1490
C+ G + + +C+ DSG+C C+ + GR CD C G Y FP+C C CNR GT VC
Sbjct: 1358 CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVC 1417
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDE 1550
D T C CK NV G C+ C+E F+L N GCT CFCFG +C SS+ +
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVD 1477
Query: 1551 MVDWYPVDVLINNTIELYPHEDVPELTN--VTVLTVGLNDGVTNGKVAYFGAPEYYLGKR 1608
M+ W+ +E D+P N + L + A + AP YLG +
Sbjct: 1478 MLGWH---------LETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDK 1528
Query: 1609 LTSYGGYLTYTV-HYTTRGDGDAV-AAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLS 1666
++SYGGYLTY + GD + PDV + G + +++ P V +
Sbjct: 1529 VSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVV 1588
Query: 1667 EEEFSTLDG-APVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDEL 1725
E F APV+R++ M L ++ + I+ Y+ + +LS V LE D G
Sbjct: 1589 EGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSG--- 1645
Query: 1726 VVRRATSVEECQCPRAYRGLSCEQCAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGIC 1781
R A +VE C CP AY G SC+ C+ G+YR L +G CVPC CNGHS+QC +GIC
Sbjct: 1646 --RIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGIC 1703
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
+NC NT G+HCE C GY+G+A G+ R ACP P+ +N+FA C + NG + C
Sbjct: 1704 VNCQHNTAGEHCERCQEGYYGNAVHGSCR-----ACPCPH-TNSFATGCVV--NGGDVRC 1755
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
+C+ GY G +CE CA GY+G P+ G C+PC+C+ N GSC + GDC+
Sbjct: 1756 SCKAGYTGTQCERCAPGYFGNPQ----KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 1806
Score = 626 bits (1547), Expect = e-178
Identities = 278/630 (44%), Positives = 377/630 (59%), Gaps = 42/630 (6%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CD C++ + K HP A+D WWQSPPLS G +YN VNLT+DLGQ FHVAY+ +K
Sbjct: 102 CDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFA 161
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G T+ PWQYF+ S DC + FG+E+ +T+DD V+C TEYS+I
Sbjct: 162 NSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRI 221
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GE+ +SL+N RP + + S L+E+T+ATN+RLR LRT LLGHL+S A++DPT
Sbjct: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGG+C+CNGHA+ C +P + C CQH+TCG C++CC+G+
Sbjct: 282 VTRRYYYSIKDISIGGQCVCNGHAEVCNINNPE---KLFRCECQHHTCGETCDRCCTGYN 338
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q++WR + CE CNCH H + C YDP+++ ++ SL+ G Y GGG C+NCQHNT
Sbjct: 339 QRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTA 398
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C YYRPYG D D C PC CDP + G CE+ SGRC C+P F +C C
Sbjct: 399 GVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRCHCKPNFHGDNCEKC 457
Query: 394 AYGYFDYPNC---------------------KPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
A GY+++P C K C CNL G E C G C C+
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVE 516
Query: 433 GKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
G C+ C G+YS P C+ C C+ +GS C +TG C C+ +G+ C++C +G Y++
Sbjct: 517 GPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDF 576
Query: 492 PTCKPCN--CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
P C+ + CD +GT + G C CK GP C +C Y+ C C
Sbjct: 577 PHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECK 632
Query: 550 CDPTGSTSTS--C-SADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI 601
C G+ S + C DG C+C ++ GG CD C GY+ Y C C CD+ G++
Sbjct: 633 CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGAL 692
Query: 602 GSTCD-DNGLCHCKSNFDGAKCDTCREQFY 630
S C +G+C C+ + G C +Y
Sbjct: 693 SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 204 bits (499), Expect = 4e-51
Identities = 260/1269 (20%), Positives = 504/1269 (39%), Gaps = 108/1269 (8%)
Query: 1901 CVNNTAGAACNLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEK 1957
C AG +C C+PG+Y D +++ C C C+ C +G CV C+ GE
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEH 1714
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNG--QCRCAKGVTGKQCDQCAAGFW 2014
C+RC ++G C C C + +T C + G +C C G TG QC++CA G++
Sbjct: 1715 CERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF 1774
Query: 2015 -NYTKDG--CDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
N K G C C+CN+ +G TG C + E D P E C +C
Sbjct: 1775 GNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC-----INQEPKDSSPA-------EECDDC 1822
Query: 2072 DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDI 2131
DSC L+ + + L + + S +++ ++ Q + LR ++ ++ I
Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-I 1881
Query: 2132 GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVV 2191
S I+ LE +L + E + +A L + R + +E + V+
Sbjct: 1882 SNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVI 1941
Query: 2192 KHVADL-----ATGLELSQQPKVDSAL--TEARQIRDDIADKDLVPKKQQAEAVFLNTTT 2244
++V L T E + P D + EA+++ ++ +++ ++AEA +
Sbjct: 1942 RNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQL 2001
Query: 2245 QIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEE 2304
+ R+ + + + ++ S+ ++ E + KL D+ A A A
Sbjct: 2002 LLNRIRTWQKTHQGENNGLAN-------SIRDSLNEYEAKLSDLRARLQEAAAQAKQANG 2054
Query: 2305 LNTKNRLSKFGNKVNSVTKLNTAAMGDLIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXX 2364
LN +N + G V ++N+ D ++
Sbjct: 2055 LNQENERA-LGAIQRQVKEINSL-QSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 2112
Query: 2365 XXXXXXXXXXXXXTGELPQFEHLTS---EATHHATMLRRRADSLRELAERENNNSRTQHX 2421
EL + TS EA HA L+ A L E+ + + +
Sbjct: 2113 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 2172
Query: 2422 XXXXXXXXXXXQEINXXXXXXXXXXXXXXNV--TKLNRILDERVRPARERSSSLLADATK 2479
I + T + L + + S LL +A
Sbjct: 2173 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 2232
Query: 2480 AQHAVDQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRV 2538
Q + Q++ P L ++ L + D + ++ + A V
Sbjct: 2233 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 2292
Query: 2539 NATIGTTFSVMSHLGPELATSKDWAQTLPKLADEG-QKMTSNVESHLKNINDMEPQISSS 2597
T V+ L P + T + +E +K ++ ++ + + + P +
Sbjct: 2293 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 2352
Query: 2598 YHTVKMXXXXXXXXXXXXXXKLQKLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVD 2657
++ + ++++L++QAR A+++ V + F+ S ++ RLP+ ++
Sbjct: 2353 IESINQQLLPLGNISD----NMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLE 2408
Query: 2658 EMSTSTHVSAYFR---TKEKDG----FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVV 2710
++ T +S + + ++E G F++YLGN + S DY+ + + +G V
Sbjct: 2409 DLKGYTSLSLFLQRPNSRENGGTENMFVMYLGN-------KDASRDYIGMAVVDGQLTCV 2461
Query: 2711 MDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA 2769
++GD A + +D+++ + + ++DR+ +R+ R + G + +
Sbjct: 2462 YNLGDRE------AELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETP 2515
Query: 2770 ---DLPGH--HTIFNLDKEKSKLYVGGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLW 2823
D+ G +T+ NLD E YVGG P D KL +SFP ++G IE + + + L+
Sbjct: 2516 GVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLY 2575
Query: 2824 NFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAP 2882
NF L + + Y F+G GYA + + + P Q + +T
Sbjct: 2576 NFKKTFNLNTTEVEPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVD 2631
Query: 2883 NGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAK 2942
GL++ G F SL ++DG++ ++ L N+E G A N+G+ H + + +
Sbjct: 2632 RGLLFFAENGDRFISLNIEDGKLMVRYKL-NSELPKERGVGDAINNGRDHSIQIKIGKLQ 2690
Query: 2943 CSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGI---LQVPDRGFDGCMRQISINGVN 2999
+ ++ +V ++ ++ T GG I + F GCM+ +
Sbjct: 2691 KRMWINVDV---QNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGV 2747
Query: 3000 LDLSENLESIGMAYGC----QFASLVSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPN 3052
+ L+ +++G+ C + SF+ L F D+ +++ Q + F+T +P+
Sbjct: 2748 VRLN---DTVGVTKKCSEDWKLVRSASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPS 2803
Query: 3053 GLLFVYVSRTQTAIMPDSISLSLVNG--KLVVVSQREQLDTGLNTYNDSQWHVLTVTHNT 3110
G+L + + T+ ++ ++L +G +L + TY D H ++V +
Sbjct: 2804 GILLDHQTWTR------NLQVTLEDGYIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDN 2857
Query: 3111 SALKLVVDD 3119
S L+L++DD
Sbjct: 2858 SGLRLLIDD 2866
Score = 171 bits (416), Expect = 4e-41
Identities = 115/356 (32%), Positives = 161/356 (45%), Gaps = 53/356 (14%)
Query: 1738 CPRAYRGLSCEQCAEGHYR-------LPSGFCVPCQCNG-HSDQCDVNTGICLNCADNTI 1789
C G++CEQCA+G+YR P G C+PC C+ H+D C+ +G C +C N
Sbjct: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-CIPCSCDPEHADGCEQGSGRC-HCKPNFH 450
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS-----CDLSENGSLIS---- 1840
GD+CE C GY+ P I P+ PS+ ++ CD + G L
Sbjct: 451 GDNCEKCAIGYYN-----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 505
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD 1897
C C+PG G RC+ C +G+Y P C+ C CS + Q P C S+ G
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP---------ICQACWCSALGSYQMP--CSSVTGQ 554
Query: 1898 CLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
C +C G C+ C G Y + +AC D G + S G C C+ V G
Sbjct: 555 C-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC--DPAGTIN--SNLGYCQCKLHVEGPT 609
Query: 1958 CDRCAPDHWGLN--TGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAG 2012
C RC +W L+ GC+ C C G S + +C +G C C V G CD C G
Sbjct: 610 CSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDG 669
Query: 2013 FWNYTKD---GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIP 2064
++ K GC C C+ G ++ MC+ +G C+C V+G+ C R PE P
Sbjct: 670 YFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR-PENNYYFP 724
Score = 169 bits (410), Expect = 2e-40
Identities = 118/388 (30%), Positives = 161/388 (41%), Gaps = 71/388 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRL---PSGF-----CVPCQCNGHSDQC-----------DV 1776
C+C G +C++C G+ + P+ + C C C+GH+ C +
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 1777 NT-------GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICACPMPYPSNNFA 1827
NT G+C+NC NT G +CE C GY+ V P C+ C+C +
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH------ 432
Query: 1828 LSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-------------EDTDLHTGDYC 1874
D E GS C+C+P + G CE CA GYY P D GD
Sbjct: 433 --ADGCEQGSG-RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDI- 488
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDE 1934
K C+C N+ P CD+ +G CL C G C+ C GFY I C AC C
Sbjct: 489 KGCDC--NLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSA 540
Query: 1935 FG--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDN 1992
G C S TG C CRPGV G++CDRC + G + C A + +
Sbjct: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAG---TINSNL 596
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV---GFMCNATGQCECLP 2046
G C+C V G C +C +WN K+ GC C C+ +V G G C C
Sbjct: 597 GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKS 656
Query: 2047 GVIGEKCDRCPERWVLIPQEGCLECDSC 2074
V G+ CD C + + + + C C
Sbjct: 657 HVGGDSCDTCEDGYFALEKSNYFGCQGC 684
Score = 139 bits (337), Expect = 2e-31
Identities = 97/341 (28%), Positives = 144/341 (42%), Gaps = 42/341 (12%)
Query: 231 CMCNG-HADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C C+ HAD CE +G C C+ N G C KC G+ + + R
Sbjct: 426 CSCDPEHADGCEQG--SGR-----CHCKPNFHGDNCEKCAIGYYNFPFCL-----RIPIF 473
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
P + + D + + L + + G+CL C+ EG C+ CR +Y
Sbjct: 474 PVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFY---- 528
Query: 350 KRWDELDVCQPCQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCT- 407
+CQ C C S C +G+CECRP C C G +D+P+C+ +
Sbjct: 529 ----SFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSS 584
Query: 408 -CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE------CKNCECNTVGSVS 460
C+ GT + G C CK + G +C C+ Y++ + C C+C+ G+VS
Sbjct: 585 ACDPAGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVS 640
Query: 461 YV--CDKLTGDCTCKSKYSGRTCNQCQAGYY-----NYPTCKPCNCDTSGTEPSICDDVS 513
C + GDC CKS G +C+ C+ GY+ NY C+ C CD G S+C S
Sbjct: 641 GTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPS 700
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
G C C+ G C + + YY L + + P G
Sbjct: 701 GVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
Score = 136 bits (330), Expect = 1e-30
Identities = 102/347 (29%), Positives = 147/347 (42%), Gaps = 54/347 (15%)
Query: 1765 CQCNGHSDQCDVNTGICL---NCADNTIGDHCEFCMSGYH----GDATVGTPRDCLICAC 1817
C CNGH++ C++N L C +T G+ C+ C +GY+ A +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1818 PMPYPSNNF----------ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTD 1867
+ SN + +L+ G + NCQ G CE CA GYY P
Sbjct: 359 -HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVP 416
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG------DA 1921
+ D C PC+C +P+ C+ +G C C N G C CA G+Y
Sbjct: 417 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIP 471
Query: 1922 IF-----------SKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
IF + + C C+ G+ CD+ G C+CRPGV G +CD C +
Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGPRCDTCRSGFYSF 530
Query: 1969 NTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN 2027
C C C + S C GQC C GVTG++CD+C +G +++ C+
Sbjct: 531 PI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587
Query: 2028 TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQE---GCLEC 2071
G + + G C+C V G C RC + + +E GC EC
Sbjct: 588 ---PAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSEC 631
Score = 127 bits (307), Expect = 7e-28
Identities = 72/206 (34%), Positives = 93/206 (45%), Gaps = 21/206 (10%)
Query: 1876 PCNC--SGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICD 1933
PC C +G P C G C C N G C CA G YG F + C C C
Sbjct: 1265 PCECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYG---FPR-CKPCSC- 1314
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG----IASESTQCD 1989
G C+ TG C C P + +C+ C + + GC CNC I + +CD
Sbjct: 1315 --GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECD 1372
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN-TGYSVGFMCNATGQCECLPGV 2048
D+GQCRC +TG+QCD+CA+GF+ + + C CNCN G G TG C C V
Sbjct: 1373 RDSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
Query: 2049 IGEKCDRCPERWVLIPQEGCLECDSC 2074
G +C+ C E + C SC
Sbjct: 1431 EGTECNVCREGSFHLDPANLKGCTSC 1456
Score = 118 bits (283), Expect = 5e-25
Identities = 66/202 (32%), Positives = 85/202 (42%), Gaps = 25/202 (12%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCEC 381
GG+C CQ N G C +C +Y C+PC C CEE +G+C C
Sbjct: 1282 GGQC-PCQPNVIGRQCTRCATGHY--------GFPRCKPCSCGRRL----CEEMTGQCRC 1328
Query: 382 RPEFQPPDCSSC---AYGYFDYPNCKPCTCNLNGT---EGEHCTPTDGLCPCKYNYAGKS 435
P P C C ++ + C+ C C+ GT C G C CK G+
Sbjct: 1329 PPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQ 1388
Query: 436 CEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC 494
C+ C G+Y PEC C CN G+ VCD TG C CK G CN C+ G ++
Sbjct: 1389 CDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFH---L 1445
Query: 495 KPCNCDTSGTEPSICDDVSGQC 516
P N G C V+ QC
Sbjct: 1446 DPAN--LKGCTSCFCFGVNNQC 1465
Score = 114 bits (275), Expect = 5e-24
Identities = 61/178 (34%), Positives = 83/178 (46%), Gaps = 18/178 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C P Y G C+ C+ GYY + L+TG C PCNC+G+ N C +G C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVN 1705
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTG--TCVCRPGVIGE 1956
C +NTAG C C G+YG+A+ +C AC C C G C C+ G G
Sbjct: 1706 CQHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 1957 KCDRCAPDHWG--LNTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
+C+RCAP ++G G C PC+C + C G C ++CD C
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 110 bits (265), Expect = 8e-23
Identities = 63/208 (30%), Positives = 89/208 (42%), Gaps = 33/208 (15%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C CQP G +C CA G+YG P CKPC+C + C+ + G C +
Sbjct: 1285 CPCQPNVIGRQCTRCATGHYGFPR---------CKPCSCGRRL-------CEEMTGQC-R 1327
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG-----MADCDSTTGTCVCRPGVIG 1955
C T C +C + + C C C G M +CD +G C C+P + G
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMA-GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITG 1386
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
+CDRCA + C PCNC +E CD G C C + V G +C+ C G +
Sbjct: 1387 RQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSF 1443
Query: 2015 NY---TKDGCDHCNCNTGYSVGFMCNAT 2039
+ GC C C + V C+++
Sbjct: 1444 HLDPANLKGCTSCFC---FGVNNQCHSS 1468
Score = 107 bits (257), Expect = 7e-22
Identities = 57/174 (32%), Positives = 81/174 (46%), Gaps = 23/174 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C C Y+G +C C GYY Y C PCNC+ + C D SG C+ C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQ 579
G C++C GYY + C C C T S +T C +G +C+C + G QC++
Sbjct: 1711 AGEHCERCQEGYYGNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 1768
Query: 580 CSPGYYKYP-----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C+PGY+ P C C+C+ +G +GS G C K + +CD C
Sbjct: 1769 CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 104 bits (249), Expect = 7e-21
Identities = 57/173 (32%), Positives = 84/173 (48%), Gaps = 25/173 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNY 431
C C P + C C+ GY+ D+ C PC CN + + C G+C C++N
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710
Query: 432 AGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQ 485
AG+ CE C++GYY C+ C C S + C GD C+CK+ Y+G C +C
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 486 AGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
GY+ P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 104 bits (249), Expect = 7e-21
Identities = 89/363 (24%), Positives = 160/363 (44%), Gaps = 24/363 (6%)
Query: 3309 RFGSRNVSRIEYAKLPGRQLEG-FDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
+FG S + + KLP L+ + +T +G ++F+ + KN F+A ++
Sbjct: 2988 QFGDIPTSHLLF-KLPQELLKPRSQFAVDMQTTSSRG-LVFHTGT---KN--SFMALYLS 3040
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPL 3427
+L + G+ I S ND WHTV +G G+L VD E S+ N+ +
Sbjct: 3041 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 3100
Query: 3428 SLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN-I 3486
S+ P Y G + + + N F+GCLK ++ + + ++ C+ +
Sbjct: 3101 SIRAPVYLGS--PPSGKPKSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 3155
Query: 3487 EDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK-DYMVLELL 3545
E G+YF + ++ L + +G E + +RPR+ TG+L+ + + ++ + L
Sbjct: 3156 EKGIYF----SEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 3211
Query: 3546 DSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFS-KPGIGA 3604
+V A++++G G + ++ K LCDG WH + D S G
Sbjct: 3212 AGKVTASMDSGAG--GTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIP 3269
Query: 3605 YTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRG-AHVG 3663
+ T L++GG + +R + + F GC+RNI V PV V + +G +
Sbjct: 3270 FPPASTQEPLHLGGAPANLTTLR-IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 3328
Query: 3664 VCP 3666
CP
Sbjct: 3329 GCP 3331
Score = 97.9 bits (233), Expect = 6e-19
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 40/203 (19%)
Query: 249 LNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDE 308
L + +C C G C C G+ +R + C PCNC+ H+ +C
Sbjct: 1649 LAVEICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------- 1697
Query: 309 KRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPH-- 366
+G G C+NCQHNT G +C +C+ Y YG C+ C C PH
Sbjct: 1698 -----------DGSGICVNCQHNTAGEHCERCQEGY---YGNAVH--GSCRACPC-PHTN 1740
Query: 367 -FSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHC 418
F+TG C G RC C+ + C CA GYF P +C+PC+CN NG G C
Sbjct: 1741 SFATG-CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-C 1798
Query: 419 TPTDGLCPCKYNYAGKSCEICED 441
P G C + E C+D
Sbjct: 1799 HPLTGDCINQEPKDSSPAEECDD 1821
Score = 95.5 bits (227), Expect = 3e-18
Identities = 56/174 (32%), Positives = 81/174 (46%), Gaps = 15/174 (8%)
Query: 566 CNCLTNFGGAQCDQCSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFD 618
C C + G C CSPGYY+ Y C+ CNC+ G D +G+C +C+ N
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTA 1711
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFA-GCGSVPAGEL-CQCKDRVQGRICNDCK 676
G C+ C+E +Y C P T SFA GC V G++ C CK G C C
Sbjct: 1712 GEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC-VVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
P Y+ + C+ C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 1821
Score = 93.5 bits (222), Expect = 1e-17
Identities = 74/261 (28%), Positives = 110/261 (42%), Gaps = 26/261 (9%)
Query: 1947 CVCRPGVIGEKCDRCAP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
C C P G+ C C+P DH GL TG C PCNC S QC D +G C C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN--GHSNQCQDGSGICVNCQHNT 1710
Query: 2002 TGKQCDQCAAGFW-NYTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCDRCP 2057
G+ C++C G++ N C C C S C G +C C G G +C+RC
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 2058 ERWVLIPQE---GCLECDSCTDALIFSVEDLSALLAN-ETMDFK-----DKADSFFTTQR 2108
+ PQ+ C C ++ + S L+ N E D D DS T
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMT-L 1829
Query: 2109 LNYISNQTELLRPKVAQLKTVDIGE-VTSSIKTLETSAKNL---LRSAEFAATDSDKQIS 2164
LN ++ E LR +QL+ + + ++ +ET AK+L L + A ++ +I
Sbjct: 1830 LNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIE 1889
Query: 2165 RAAKLAEDAERTLAAVRESAR 2185
+ D + ++E A+
Sbjct: 1890 GLERELTDLNQEFETLQEKAQ 1910
Score = 91.9 bits (218), Expect = 4e-17
Identities = 52/173 (30%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 424 LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
+C C YAG SC+ C GY Y+ C C CN S C +G C C+
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHN 1709
Query: 476 YSGRTCNQCQAGYYN---YPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQC 530
+G C +CQ GYY + +C+ C C + + + C G +C CKAG+ G +C++C
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC---NCLTNFGGAQCDQC 580
GY+ C PC+C+ G + G C + +CD C
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 84.2 bits (199), Expect = 8e-15
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 37/235 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNG---HSDQCDVNTGICLNCADNTIGDH 1792
C C G C+ C G Y P C C C+ + C TG C C G
Sbjct: 509 CLCRPGVEGPRCDTCRSGFYSFP--ICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQR 565
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSE--NGSLISCNCQPGYGGA 1850
C+ C+SG A P+ + + +CD + N +L C C+ G
Sbjct: 566 CDRCLSG----------------AYDFPHCQGSSS-ACDPAGTINSNLGYCQCKLHVEGP 608
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C C Y+ + D + +G C C C G C +GDC C ++ G +C
Sbjct: 609 TCSRCKLLYWNL--DKENPSG--CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSC 663
Query: 1911 NLCAPGFYGDAIFSKN---CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDR 1960
+ C G++ A+ N C C CD G C +G C CR V+G+ C R
Sbjct: 664 DTCEDGYF--ALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716
Score = 65.7 bits (153), Expect = 3e-09
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 1687 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 1733
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + +NG G +C +C+ G C +C P Y +G
Sbjct: 1734 CPC----------PHTNSFATGCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 1776
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 1777 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 1825
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/157 (28%), Positives = 57/157 (36%), Gaps = 31/157 (19%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC T PQC C E + CE CNC T PE D
Sbjct: 1326 CRCPPRTVRPQCEVC----ETHSFSFH---PMAGCEGCNCSRRGTIEAAMPECD------ 1372
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD-PHFSTGNC 372
G+C C+ G C++C +YR C PC C+ G C
Sbjct: 1373 ------RDSGQC-RCKPRITGRQCDRCASGFYR--------FPECVPCNCNRDGTEPGVC 1417
Query: 373 EEESGRCECRPEFQPPDCSSCAYGYF--DYPNCKPCT 407
+ +G C C+ + +C+ C G F D N K CT
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCT 1454
Score = 54.4 bits (125), Expect = 7e-06
Identities = 45/190 (23%), Positives = 70/190 (36%), Gaps = 27/190 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD------VNTGICLNCADNT 1788
+C+C G C++C G Y P C G S CD N G C C +
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFP-------HCQGSSSACDPAGTINSNLGYC-QCKLHV 605
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C Y + P C C C + + + + + + C+C+ G
Sbjct: 606 EGPTCSRCKLLY-WNLDKENPSGCSECKC---HKAGTVSGTGECRQGDG--DCHCKSHVG 659
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
G C+ C GY+ + + + G C+ C C +I C +G C +C + G
Sbjct: 660 GDSCDTCEDGYFALEKSN--YFG--CQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGK 712
Query: 1909 ACNLCAPGFY 1918
C +Y
Sbjct: 713 VCQRPENNYY 722
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCN--GHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P F C PC CN G C TG C+N D++
Sbjct: 1755 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 1814
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 1815 PAEECDDCDS 1824
Score = 50.8 bits (116), Expect = 9e-05
Identities = 60/292 (20%), Positives = 118/292 (40%), Gaps = 30/292 (10%)
Query: 2725 RVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEK 2784
R+ + D +W+ V+ G + +L + D + ++E LPG+ TI +
Sbjct: 3056 RIKSKEKCNDGKWHTVVFGHDGEKGRLVV--------DGLRAREGSLPGNSTI----SIR 3103
Query: 2785 SKLYVGGVPSDAKLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQ 2844
+ +Y+G PS K + + +F G ++ + P+ + ++ + S
Sbjct: 3104 APVYLGSPPS-GKPKSLPTNSFVGCLKNFQLDSKPL----YTPSSSFG-------VSSCL 3151
Query: 2845 SGPQE---YRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
GP E Y + G+ +A L P+ V LI++ + G + ++
Sbjct: 3152 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 3211
Query: 2902 DGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSA 2961
G+V + G V ++ DG+WH + L +D + P
Sbjct: 3212 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 3271
Query: 2962 DIPSLDTMNFGG--NNKGILQVPD-RGFDGCMRQISINGVNLDLSENLESIG 3010
+ + ++ GG N L++P + F GC+R I +N + + ++E LE G
Sbjct: 3272 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 3323
Score = 50.0 bits (114), Expect = 2e-04
Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 9/309 (2%)
Query: 2866 LTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
L P+S Q + +T + GL++ G F +L + GR L +LG + + +
Sbjct: 3006 LKPRS-QFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGR--LVFALGTDGKKLRIKSKEK 3062
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKG-ILQVPDR 2984
NDGKWH + K L VD + S ++ I + G G +P
Sbjct: 3063 CNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTN 3122
Query: 2985 GFDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTL 3044
F GC++ ++ L + + G + F+ ++ P+ L
Sbjct: 3123 SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKL 3182
Query: 3045 KFKTAKPNGL--LFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-TGLNTYNDSQW 3101
F + +P L + +++ + + V + + T + D QW
Sbjct: 3183 VF-SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQW 3241
Query: 3102 HVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFT 3161
H + VT L L +D ++ P P L +GG P + + + F
Sbjct: 3242 HSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGA-PANLTTLRIPVWKSFF 3300
Query: 3162 GCIGDATIN 3170
GC+ + +N
Sbjct: 3301 GCLRNIHVN 3309
Score = 49.2 bits (112), Expect = 3e-04
Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 27/111 (24%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C+ T E A P + + CRC+ G QC++C SGF +R + C P
Sbjct: 1356 CNCSRRG-TIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE------CVP 1404
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
CNC+ TE P + + G G CL C+ N EG CN CR
Sbjct: 1405 CNCNRDGTE----PGVCD-----------PGTGACL-CKENVEGTECNVCR 1439
>AF005258-1|AAC51867.1| 1486|Homo sapiens laminin alpha 3b chain
protein.
Length = 1486
Score = 608 bits (1501), Expect = e-172
Identities = 389/1268 (30%), Positives = 572/1268 (45%), Gaps = 118/1268 (9%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE--EESGRCECRPEFQPPDCSSCAYGYFD 399
PT R Y ++ + C C+ H N E+ RCEC+ C C GY +
Sbjct: 244 PTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY-N 302
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSV 459
P + C C C + +A +C YY P+ + E +
Sbjct: 303 QRRLGPAAWE----QSHECEA----CNC-HGHAS-NC------YYDPDVERHEASLNTQG 346
Query: 460 SYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYN---YPT-----CKPCNCDTSGTEPSICD 510
Y G C C+ +G C QC GYY P C PC+CD + C+
Sbjct: 347 IYAGG---GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CE 401
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGR---------------ERQCVPCNCDPTGS 555
SG+C CK F G C++C GY R C+C+ G
Sbjct: 402 QGSGRCHCKPNFHGDNCEKCAIGYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGV 461
Query: 556 TSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHCK 614
C A G+C C G +CD C G+Y +P C +C C GS C G C C+
Sbjct: 462 LPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECR 521
Query: 615 SNFDGAKCDTCREQFYNYPACEECN--CDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
G +CD C Y++P C+ + CDP G G CQCK V+G C
Sbjct: 522 PGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINWNLG--------YCQCKLHVEGPTC 573
Query: 673 NDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGF 732
+ CK LYWNL + NP GC +C C+ GT++ G C G C CK HVG CD C DG+
Sbjct: 574 SRCKLLYWNLDKENPSGCSECKCHKGGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGY 633
Query: 733 YRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQFQ 792
+ L+ ++ FGC C CDIGG++ + C +G C C V G+ C +P +YFP LH +
Sbjct: 634 FALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMK 693
Query: 793 YEVEDGVTQSG-PVRYRNSEEVFPEYSWKGYVVFSLLQNEVINIIQITKS--SLYRMVLK 849
YE+EDG T +G +R+ FPE+SW+GY + +QN+V + + KS SL+R++L+
Sbjct: 694 YEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMASVQNDVRITLNVGKSSGSLFRVILR 753
Query: 850 YANPLRDPVVANIVITPESVVDIQQKFNVYLRPTVLPQLVTVAGDKGVTPAPFVMNPGNW 909
Y NP + V +I I P S Q K ++L P+ P VT+ G+ G PF + PG W
Sbjct: 754 YVNPGTEAVSGHITIYP-SWGAAQSKEIIFL-PSKEPAFVTLPGN-GFAD-PFSITPGMW 809
Query: 910 TVTIKTNKEIMIDYFVLIPEAYYEATILTKMVDKPCIVG--DKKLCRQFAY-PSLSGKST 966
IK + +++DY VL+P YYEA+ L V +PC ++ C + + P T
Sbjct: 810 VACIKA-EGVLLDYLVLLPRDYYEASDLQLPVTEPCAYAGPPQENCLLYQHLPVTRFPCT 868
Query: 967 ADVTSLVTSVDSFIDDPVQLSELKVEPNTIPILRTTLQYNMRIEKP--GQYVLLVEYVTP 1024
+ +D P + + ++ ++R+ P G YV++VEY T
Sbjct: 869 RSCEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRVRIPQVGPYVVVVEYSTE 928
Query: 1025 AARNQDLNTGNSTYSSVVKTPVTIKFQSGPDDQHLVETDGIINFNDCPYTAPCRQVMVDD 1084
AA+ ++ + SV+ G +N C Y+ CR ++D
Sbjct: 929 AAQLFVVDANVKSSGSVLA--------------------GQVNIYSCNYSVLCRSAVIDH 968
Query: 1085 YSRI-QFVTVTDPNNVVFLLDQPDTEAAIKSVVAIPQAEWHLDYLTPRPYCLRRNGRCDP 1143
SRI + +TD + L + V IP E+ +Y+ P+ +C+ GR
Sbjct: 969 MSRIAMYELLTDAD---IQLKGHMARFLLHQVCIIPIEEYSAEYVRPQVHCIASYGRFVN 1025
Query: 1144 AVFNAVVDAKKVE-----FESGTGGDRETRPQILNNSTTV---VYLPTQSEPVILEGKVS 1195
V A + + +G PQ + S V V L V L G+V
Sbjct: 1026 QSATCVSLAHETPPTALILDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVP 1085
Query: 1196 APGEYLFMVHYYQPDHPESTMEVTVNTDGQKQETNLPIQHCPSNSGCRALLRKPDTSTSF 1255
G Y+F++H+YQ HP +V+V+ G + + CP GCR + F
Sbjct: 1086 HLGRYVFVIHFYQAAHPTFPAQVSVD-GGWPRAGSFHASFCPHVLGCRDQVIA--EQIEF 1142
Query: 1256 LVNE-NFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQ-CASYN-Y 1312
++E K K + L VLV+ A ++ +L + + +D + EFI + C N +
Sbjct: 1143 DISEPEVAATVKVPEGKSLVLVRVLVVPAENYDSQILHKKS-MDKSLEFITKFCGEKNSF 1201
Query: 1313 YISPNETG-LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS 1371
Y+ P C+ + S+ + Y+ GA PC C G T C+ GG P G +
Sbjct: 1202 YLDPQTASRFCKNSARSLVAFYHKGALPCECHPTG-TGPHCSPEGGSAHASPTSSGGSAP 1260
Query: 1372 ACRTGYYGFPNC--RPCHCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCD 1428
A + YGFP C +PC C +C++ G C CP C+ C+ ++F+ GC+
Sbjct: 1261 AVQQATYGFPRCKPKPCSC-GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSLHPMAGCE 1319
Query: 1429 DCNCNPLGVVGNQL-QCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTY 1487
CNC+ G + + +C+ DSG+C C+ + GR CD C G Y FP+C C CNR GT
Sbjct: 1320 GCNCSRRGTIEAAMPRCDRDSGQCGCKPRITGRQCDRCASGFYGFPECVPCNCNRDGTEP 1379
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAA 1547
VCD T C CK NV G C+ C+E F+L N GCT CFCFG +C SS+
Sbjct: 1380 GVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTK 1439
Query: 1548 IDEMVDWY 1555
+M+ W+
Sbjct: 1440 FVDMLGWH 1447
Score = 589 bits (1454), Expect = e-167
Identities = 270/630 (42%), Positives = 363/630 (57%), Gaps = 43/630 (6%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CD C++ + K HP A+D WWQSPPLS G +YN VNLT+DLGQ FHVAY+ +K
Sbjct: 66 CDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFA 125
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRPELWVLE+S D+G T+ PWQYF+ S DC + FG+E+ +T+DD V+C TEYS+I
Sbjct: 126 NSPRPELWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRI 185
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GE+ +SL+N RP + + S L+ + L LRT LLGHL+S A++DPT
Sbjct: 186 VPLENGEVVVSLINGRPGAKNFTFSHTLRGVYQGNKHPLAFLRTNTLLGHLISKAQRDPT 245
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGG+C+CNGHA+ C +P + C CQH+TCG C++CC+G+
Sbjct: 246 VTRRYYYSIKDISIGGQCVCNGHAEVCNINNPE---KLFRCECQHHTCGETCDRCCTGYN 302
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q++ + CE CNCH H + C YDP+++ SL+ G Y GGG C+NCQHNT
Sbjct: 303 QRRLGPAAWEQSHECEACNCHGHASNCYYDPDVERHEASLNTQGIYAGGGVCINCQHNTA 362
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C YYRPYG D D C PC CDP + G CE+ SGRC C+P F +C C
Sbjct: 363 GVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRCHCKPNFHGDNCEKC 421
Query: 394 AYGYFDYPNC---------------------KPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
A GY ++P C K C CNL G E C G C C+
Sbjct: 422 AIGY-NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVE 479
Query: 433 GKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
G C+ C G+YS P C+ C C+ +GS C +TG C C+ +G+ C++C +G Y++
Sbjct: 480 GPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDF 539
Query: 492 PTCKPCN--CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
P C+ + CD +GT + G C CK GP C +C Y+ C C
Sbjct: 540 PHCQGSSSACDPAGT----INWNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECK 595
Query: 550 CDPTGSTSTS--C-SADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI 601
C G+ S + C DG C+C ++ GG CD C GY+ Y C C CD+ G++
Sbjct: 596 CHKGGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGAL 655
Query: 602 GSTCD-DNGLCHCKSNFDGAKCDTCREQFY 630
S C +G+C C+ + G C +Y
Sbjct: 656 SSMCSGPSGVCQCREHVVGKVCQRPENNYY 685
Score = 168 bits (409), Expect = 3e-40
Identities = 113/356 (31%), Positives = 161/356 (45%), Gaps = 54/356 (15%)
Query: 1738 CPRAYRGLSCEQCAEGHYR-------LPSGFCVPCQCN-GHSDQCDVNTGICLNCADNTI 1789
C G++CEQCA+G+YR P G C+PC C+ H+D C+ +G C +C N
Sbjct: 357 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-CIPCSCDPEHADGCEQGSGRC-HCKPNFH 414
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS-----CDLSENGSLIS---- 1840
GD+CE C GY+ + P P+ PS+ ++ CD + G L
Sbjct: 415 GDNCEKCAIGYNFPFCLRIP------IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 468
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD 1897
C C+PG G RC+ C +G+Y P C+ C CS + Q P C S+ G
Sbjct: 469 HGRCLCRPGVEGPRCDTCRSGFYSFP---------ICQACWCSALGSYQMP--CSSVTGQ 517
Query: 1898 CLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
C +C G C+ C G Y + +A CD G + + G C C+ V G
Sbjct: 518 C-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSA--CDPAGTINWN--LGYCQCKLHVEGPT 572
Query: 1958 CDRCAPDHWGLN--TGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAG 2012
C RC +W L+ GC+ C C G S + +C +G C C V G CD C G
Sbjct: 573 CSRCKLLYWNLDKENPSGCSECKCHKGGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDG 632
Query: 2013 FWNYTKD---GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIP 2064
++ K GC C C+ G ++ MC+ +G C+C V+G+ C R PE P
Sbjct: 633 YFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR-PENNYYFP 687
Score = 167 bits (406), Expect = 7e-40
Identities = 120/387 (31%), Positives = 162/387 (41%), Gaps = 70/387 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHY--RL-PSGF-----CVPCQCNGHSDQC-----------DV 1776
C+C G +C++C G+ RL P+ + C C C+GH+ C +
Sbjct: 283 CECQHHTCGETCDRCCTGYNQRRLGPAAWEQSHECEACNCHGHASNCYYDPDVERHEASL 342
Query: 1777 NT-------GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICACPMPYPSNNFA 1827
NT G+C+NC NT G +CE C GY+ V P C+ C+C +
Sbjct: 343 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH------ 396
Query: 1828 LSCDLSENGSLISCNCQPGYGGARCEYCAAGY------------YGIPEDTDLHTGDYCK 1875
D E GS C+C+P + G CE CA GY P D GD K
Sbjct: 397 --ADGCEQGSG-RCHCKPNFHGDNCEKCAIGYNFPFCLRIPIFPVSTPSSEDPVAGDI-K 452
Query: 1876 PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF 1935
C+C N+ P CD+ +G CL C G C+ C GFY I C AC C
Sbjct: 453 GCDC--NLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSAL 504
Query: 1936 G--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG 1993
G C S TG C CRPGV G++CDRC + G + C A + + G
Sbjct: 505 GSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAG---TINWNLG 560
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV---GFMCNATGQCECLPG 2047
C+C V G C +C +WN K+ GC C C+ G +V G G C C
Sbjct: 561 YCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKGGTVSGTGECRQGDGDCHCKSH 620
Query: 2048 VIGEKCDRCPERWVLIPQEGCLECDSC 2074
V G+ CD C + + + + C C
Sbjct: 621 VGGDSCDTCEDGYFALEKSNYFGCQGC 647
Score = 136 bits (329), Expect = 1e-30
Identities = 99/346 (28%), Positives = 146/346 (42%), Gaps = 53/346 (15%)
Query: 1765 CQCNGHSDQCDVNTGICL---NCADNTIGDHCEFCMSGYH----GDATVGTPRDCLICAC 1817
C CNGH++ C++N L C +T G+ C+ C +GY+ G A +C C C
Sbjct: 263 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRLGPAAWEQSHECEACNC 322
Query: 1818 PMPYPSNNF----------ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTD 1867
+ SN + +L+ G + NCQ G CE CA GYY P
Sbjct: 323 -HGHASNCYYDPDVERHEASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVP 380
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF---------- 1917
+ D C PC+C +P+ C+ +G C C N G C CA G+
Sbjct: 381 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYNFPFCLRIPI 435
Query: 1918 ------YGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
+ + + C C+ G+ CD+ G C+CRPGV G +CD C +
Sbjct: 436 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGPRCDTCRSGFYSFP 494
Query: 1970 TGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
C C C + S C GQC C GVTG++CD+C +G +++ C+
Sbjct: 495 I---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDP 551
Query: 2029 GYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQE---GCLEC 2071
++ + G C+C V G C RC + + +E GC EC
Sbjct: 552 AGTINW---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSEC 594
Score = 134 bits (325), Expect = 4e-30
Identities = 101/346 (29%), Positives = 146/346 (42%), Gaps = 53/346 (15%)
Query: 231 CMCNG-HADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C C+ HAD CE +G C C+ N G C KC G+ N+ C
Sbjct: 390 CSCDPEHADGCEQG--SGR-----CHCKPNFHGDNCEKCAIGY---------NFP--FCL 431
Query: 290 PCNCHNHTTECTYDPEI-DEKRLSLDINGRY----EGGGKCLNCQHNTEGINCNKCRPTY 344
+T + DP D K ++ G + G+CL C+ EG C+ CR +
Sbjct: 432 RIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGF 490
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
Y +CQ C C S C +G+CECRP C C G +D+P+C
Sbjct: 491 Y--------SFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 542
Query: 404 KPCT--CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE------CKNCECNT 455
+ + C+ GT + G C CK + G +C C+ Y++ + C C+C+
Sbjct: 543 QGSSSACDPAGTINWNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHK 598
Query: 456 VGSVSYV--CDKLTGDCTCKSKYSGRTCNQCQAGYY-----NYPTCKPCNCDTSGTEPSI 508
G+VS C + GDC CKS G +C+ C+ GY+ NY C+ C CD G S+
Sbjct: 599 GGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSM 658
Query: 509 CDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
C SG C C+ G C + + YY L + + P G
Sbjct: 659 CSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 704
Score = 105 bits (252), Expect = 3e-21
Identities = 64/204 (31%), Positives = 88/204 (43%), Gaps = 16/204 (7%)
Query: 1876 PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF 1935
PC C +P G S G ++G + YG F + C C
Sbjct: 1229 PCEC----HPTGTGPHCSPEGGSAHASPTSSGGSAPAVQQATYG---FPR-CKPKPCS-C 1279
Query: 1936 GMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG----IASESTQCDDD 1991
G C+ TG C C P + +C+ C + L+ GC CNC I + +CD D
Sbjct: 1280 GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSLHPMAGCEGCNCSRRGTIEAAMPRCDRD 1339
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN-TGYSVGFMCNATGQCECLPGVIG 2050
+GQC C +TG+QCD+CA+GF+ + + C CNCN G G TG C C V G
Sbjct: 1340 SGQCGCKPRITGRQCDRCASGFYGFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENVEG 1397
Query: 2051 EKCDRCPERWVLIPQEGCLECDSC 2074
+C+ C E + C SC
Sbjct: 1398 TECNVCREGSFHLDPANLKGCTSC 1421
Score = 98.7 bits (235), Expect = 3e-19
Identities = 80/302 (26%), Positives = 118/302 (39%), Gaps = 58/302 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGH-----YRLP-------------SGFCVPCQCNGHS---DQC 1774
C C + G +CE+CA G+ R+P +G C CN + C
Sbjct: 407 CHCKPNFHGDNCEKCAIGYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC 466
Query: 1775 DVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
D + G CL C G C+ C SG++ C C C ++ + C S
Sbjct: 467 DAH-GRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWCS---ALGSYQMPCS-SV 514
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI 1894
G C C+PG G RC+ C +G Y P +C G+ + DP +
Sbjct: 515 TG---QCECRPGVTGQRCDRCLSGAYDFP--------------HCQGSSSACDPAGTINW 557
Query: 1895 NGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTACICDE----FGMADCDSTTGTCVC 1949
N +C + G C+ C ++ D C+ C C + G +C G C C
Sbjct: 558 NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKGGTVSGTGECRQGDGDCHC 617
Query: 1950 RPGVIGEKCDRCAPDHWGLNTG--LGCTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQC 2006
+ V G+ CD C ++ L GC C C I S+ C +G C+C + V GK C
Sbjct: 618 KSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVC 677
Query: 2007 DQ 2008
+
Sbjct: 678 QR 679
Score = 91.9 bits (218), Expect = 4e-17
Identities = 62/184 (33%), Positives = 83/184 (45%), Gaps = 24/184 (13%)
Query: 1762 CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPY 1821
C P C+ C+ TG C C T+ CE C + H ++ C C C
Sbjct: 1272 CKPKPCSCGRRLCEEMTGQC-RCPPRTVRPQCEVCET--HS-FSLHPMAGCEGCNCSRRG 1327
Query: 1822 PSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSG 1881
CD ++G C C+P G +C+ CA+G+YG PE C PCNC
Sbjct: 1328 TIEAAMPRCD-RDSGQ---CGCKPRITGRQCDRCASGFYGFPE---------CVPCNC-- 1372
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD- 1939
N + +PG CD G CL C N G CN+C G F+ D K CT+C C FG+ +
Sbjct: 1373 NRDGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFC--FGVNNQ 1429
Query: 1940 CDST 1943
C S+
Sbjct: 1430 CHSS 1433
Score = 91.5 bits (217), Expect = 5e-17
Identities = 61/224 (27%), Positives = 90/224 (40%), Gaps = 28/224 (12%)
Query: 1827 ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP--CNCSGNIN 1884
AL C+ G+ +C P G A ++G + CKP C+C +
Sbjct: 1227 ALPCECHPTGT--GPHCSPEGGSAHASPTSSGGSAPAVQQATYGFPRCKPKPCSCGRRL- 1283
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG-----MAD 1939
C+ + G C +C T C +C + + C C C G M
Sbjct: 1284 ------CEEMTGQC-RCPPRTVRPQCEVCETHSFSLHPMA-GCEGCNCSRRGTIEAAMPR 1335
Query: 1940 CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCA 1998
CD +G C C+P + G +CDRCA +G C PCNC +E CD G C C
Sbjct: 1336 CDRDSGQCGCKPRITGRQCDRCASGFYGFPE---CVPCNCNRDGTEPGVCDPGTGACLCK 1392
Query: 1999 KGVTGKQCDQCAAGFWNY---TKDGCDHCNCNTGYSVGFMCNAT 2039
+ V G +C+ C G ++ GC C C + V C+++
Sbjct: 1393 ENVEGTECNVCREGSFHLDPANLKGCTSCFC---FGVNNQCHSS 1433
Score = 62.5 bits (145), Expect = 3e-08
Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQ---CDVNTGICLNCADNTIGD 1791
+C C G C++CA G Y P CVPC CN + CD TG CL C +N G
Sbjct: 1342 QCGCKPRITGRQCDRCASGFYGFPE--CVPCNCNRDGTEPGVCDPGTGACL-CKENVEGT 1398
Query: 1792 HCEFCMSG-YHGDATVGTPRDCLICAC 1817
C C G +H D + C C C
Sbjct: 1399 ECNVCREGSFHLDP--ANLKGCTSCFC 1423
Score = 54.0 bits (124), Expect = 1e-05
Identities = 45/190 (23%), Positives = 69/190 (36%), Gaps = 27/190 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDV------NTGICLNCADNT 1788
+C+C G C++C G Y P C G S CD N G C C +
Sbjct: 517 QCECRPGVTGQRCDRCLSGAYDFP-------HCQGSSSACDPAGTINWNLGYC-QCKLHV 568
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C Y + P C C C + + + + + C+C+ G
Sbjct: 569 EGPTCSRCKLLY-WNLDKENPSGCSECKC---HKGGTVSGTGECRQGDG--DCHCKSHVG 622
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
G C+ C GY+ + + + G C+ C C +I C +G C +C + G
Sbjct: 623 GDSCDTCEDGYFALEKSN--YFG--CQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGK 675
Query: 1909 ACNLCAPGFY 1918
C +Y
Sbjct: 676 VCQRPENNYY 685
Score = 51.2 bits (117), Expect = 7e-05
Identities = 42/157 (26%), Positives = 56/157 (35%), Gaps = 31/157 (19%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC T PQC C E + + CE CNC T P D
Sbjct: 1291 CRCPPRTVRPQCEVC----ETHSFSLH---PMAGCEGCNCSRRGTIEAAMPRCD------ 1337
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD-PHFSTGNC 372
G+C C+ G C++C +Y C PC C+ G C
Sbjct: 1338 ------RDSGQC-GCKPRITGRQCDRCASGFY--------GFPECVPCNCNRDGTEPGVC 1382
Query: 373 EEESGRCECRPEFQPPDCSSCAYGYF--DYPNCKPCT 407
+ +G C C+ + +C+ C G F D N K CT
Sbjct: 1383 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCT 1419
Score = 44.4 bits (100), Expect = 0.008
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 27/111 (24%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C+ T E A P + + C C+ G QC++C SGF + C P
Sbjct: 1321 CNCSRRG-TIEAAMPRCDRDSGQCGCKPRITGRQCDRCASGF----------YGFPECVP 1369
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
CNC+ TE P + + G G CL C+ N EG CN CR
Sbjct: 1370 CNCNRDGTE----PGVCD-----------PGTGACL-CKENVEGTECNVCR 1404
>X58531-1|CAA41418.1| 2628|Homo sapiens laminin A chain protein.
Length = 2628
Score = 540 bits (1333), Expect = e-152
Identities = 290/777 (37%), Positives = 412/777 (53%), Gaps = 82/777 (10%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-C--DDN------- 1397
QC C+ N G +C+ C GY+ P C C+C + A C D++
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 1398 ----------GMCI-CPKNVEGENCDRC-----KPYTFNFDVQRGCDDCNCNPLG----- 1436
G+CI C +N G NC+ C +P+ + C CNC+P+G
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 1437 VVGNQLQCEADSGK----CACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQ 1492
+ + L + ++GK C C+E G CD C G+ +P C C CN G+ D +
Sbjct: 409 CIKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD--EP 466
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMV 1552
T C CK NV G+ACD CK ++NL++ NP GC++CFCFG + CSS + ++ M
Sbjct: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPLGQVNSMS 526
Query: 1553 DWYPVDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVA---YFGAPEYYLGKRL 1609
W D++ I +D + V +N+ ++A Y+ APE YLG +L
Sbjct: 527 GWLVTDLISPRKIP--SQQDALGGRH----QVSINNTAVMQRLAPKYYWAAPEAYLGNKL 580
Query: 1610 TSYGGYLTYTVHY---TTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGM--PWTHSVK 1664
T++GG+L YTV Y D + ++ DVII G NG + E + + + V+
Sbjct: 581 TAFGGFLKYTVSYDIPVETVDSNLMSHADVIIKG-NGLTLSTQAEGLSLQPYEEYLNVVR 639
Query: 1665 LSEEEFSTLDGA-PVTRDQFMHALVNISGLYIRASYWEYSIET-SLSNVVLEIGVDYYMG 1722
L E F + RDQ M L N++ L IRA+Y + L +V L+I +
Sbjct: 640 LVPENFQDFHSKRQIDRDQLMTVLANVTHLLIRATYNSAKMALYRLESVSLDIASSNAI- 698
Query: 1723 DELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----GFCVPCQCNGHSDQCDVNT 1778
+LVV A VE C+CP+ Y G SCE C G+YR+ G C PC+C+GH+ +C+V+
Sbjct: 699 -DLVV--AADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH- 754
Query: 1779 GICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSL 1838
G+C+ CA NT G HCE C+ G++G+ + GTP DC CACP+ SNNF+ +C L++ +
Sbjct: 755 GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEV 814
Query: 1839 ISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
+ C PGY GA CE CA GYYG P G+ C PC+CSGN++P + G CDS+ G+C
Sbjct: 815 VCDWCAPGYSGAWCERCADGYYGNP----TVPGESCVPCDCSGNVDPSEAGHCDSVTGEC 870
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRPGVIGE 1956
LKC+ NT GA C CA GFYGDA+ +KNC AC C G A C TG C C+P V G+
Sbjct: 871 LKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQ 930
Query: 1957 KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
+CD+C ++GL++G GC PCNC +A + D GQC C GV GK+CD+CA GF+ Y
Sbjct: 931 QCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAY 990
Query: 2017 TKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE-RWVLIPQEGCLECD 2072
C C+C ++ TG+C C P G KC+ C + W + GC C+
Sbjct: 991 QDGSCTPCDC--PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACN 1045
Score = 384 bits (945), Expect = e-105
Identities = 197/460 (42%), Positives = 265/460 (57%), Gaps = 35/460 (7%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C ICD N N ++HP +A+D WWQSP + G +Y+ V +T+DL Q F VAYV +K
Sbjct: 66 CRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIK 125
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDC-ERYFGKESLQPIT--KDDSVICST 148
N+PRP W+LE+S D G TF PWQY++ S +C RY P T DD VIC++
Sbjct: 126 AANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTS 184
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YS++VPLE GEI SL+N RPS++ S L E+T A +RLR R + L LM+++
Sbjct: 185 YYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRFERIRTLNADLMTLS 242
Query: 209 RQ-----DPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+ DP + RRY+YSIKDIS+GG C+C GHA +C P D L C+C+HNTCG
Sbjct: 243 HREPKELDPMLPRRYYYSIKDISVGGMCICYGHASSC-PWDETTKK--LQCQCEHNTCGE 299
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
CN+CC G+ Q+ WR +CE CNCHN +C YD + +++ SL+ G++ GGG
Sbjct: 300 SCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGG 359
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-C---------- 372
C+NC NT GINC C YYRP+ E + C+PC CDP S + C
Sbjct: 360 VCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLE 419
Query: 373 -EEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
++ G+C C+ + C C GY DYP C C CN G+ + P G C CK N
Sbjct: 420 NGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDE--PCTGPCVCKENV 477
Query: 432 AGKSCEICEDGYYSPECKN---C-ECNTVGSVSYVCDKLT 467
GK+C+ C+ G+Y+ + KN C EC G VS VC L+
Sbjct: 478 EGKACDRCKPGFYNLKEKNPRGCSECFCFG-VSDVCSSLS 516
Score = 373 bits (918), Expect = e-102
Identities = 220/653 (33%), Positives = 321/653 (49%), Gaps = 59/653 (9%)
Query: 1316 PNETGL----CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS 1371
PN TG C + + S + G RPC C GS C T GQC C P V G+ C
Sbjct: 925 PNVTGQQCDQCLHGYYGLDSGH--GCRPCNCSVAGSVSDGC-TDEGQCHCVPGVAGKRCD 981
Query: 1372 ACRTGYYGFPN--CRPCHCPSTA-ICD-DNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+Y + + C PC CP T CD + G C+CP + +G C+ C+ + +D + GC
Sbjct: 982 RCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGC 1041
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTY 1487
CNC+ +G ++ C+ +G C C+ GR C C G+ FPDC C C+ GT+
Sbjct: 1042 QACNCSLVGSTHHR--CDVVTGHCQCKSKFGGRACVQCSLGYRDFPDCVPCDCDLRGTSG 1099
Query: 1488 DVCD---------QNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRC 1538
D C+ + T C CK NV G C+ C+E F L+ DNP GC+ CFC G + C
Sbjct: 1100 DACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLC 1159
Query: 1539 SS-SYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAY 1597
S Y + D P+ +++ + E V +L + Y
Sbjct: 1160 SELEDYVRTPVTLGSD-QPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFY 1218
Query: 1598 FGAPEYYLGKRLTSYGGYLTYTV-HYTTRGDGDAVAAPDVIIAGPN--GYLVHNSVEQPP 1654
+ P+ + G +L +YGG L Y+V Y+ G G + P V+I G +++ P
Sbjct: 1219 WRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPE 1278
Query: 1655 VGMPWTHSVKLSE---EEFSTLDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNV 1711
G+ V + E + F+++ PVTR+ FM L +I + I+ASY + ++ +S++
Sbjct: 1279 NGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDI 1338
Query: 1712 VLEIG--VDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR--LPSGF------ 1761
+E+G + +E V A+ +E C CP G SC+ CA G++R LP+G
Sbjct: 1339 SMEVGRKAEKLHPEEEV---ASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRP 1395
Query: 1762 ----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
CVPC CN HSD CD NTG CLNC DNT GDHC+ C SGY+G T G+ DC +CAC
Sbjct: 1396 LVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVT-GSASDCALCAC 1454
Query: 1818 PMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPC 1877
P P+ +F+ +C L + C GY G CE C++ YYG P+ G C+ C
Sbjct: 1455 PHSPPA-SFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQT----PGGSCQKC 1509
Query: 1878 NCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTAC 1930
+C N + G CD +G C+ C +G C+ C P + +C +C
Sbjct: 1510 DC--NPHGSVHGDCDRTSGQCV-CRLGASGLRCDECEP---RHILMETDCVSC 1556
Score = 290 bits (712), Expect = 6e-77
Identities = 163/477 (34%), Positives = 219/477 (45%), Gaps = 66/477 (13%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C G C C SG+ +R+ C+PC CH H EC
Sbjct: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-- 371
G C+ C HNT G++C +C P +Y R D CQPC C ++ N
Sbjct: 755 ---------GVCIACAHNTTGVHCEQCLPGFYGE-PSRGTPGD-CQPCACPLTIASNNFS 803
Query: 372 --CEEESGR---CE-CRPEFQPPDCSSCAYGYFDYP-----NCKPCTC--NLNGTEGEHC 418
C G C+ C P + C CA GY+ P +C PC C N++ +E HC
Sbjct: 804 PTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHC 863
Query: 419 TPTDGLC-PCKYNYAGKSCEICEDGYY-----SPECKNCECNTVGSVSYVCDKLTGDCTC 472
G C C N G CE C DG+Y + C+ CEC+ GS S VC TG C C
Sbjct: 864 DSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDC 923
Query: 473 KSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ 529
K +G+ C+QC GYY + C+PCNC +G+ C D GQC C G G RCD+
Sbjct: 924 KPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDR 982
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYP 588
C G+Y ++ C PC+C T +T C + G+C C + G +C++C G++ Y
Sbjct: 983 CAHGFYAY---QDGSCTPCDCPHTQNT---CDPETGECVCPPHTQGVKCEECEDGHWGYD 1036
Query: 589 ---DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRG 644
C +CNC + GS CD G C CKS F G C C + ++P C C+CD RG
Sbjct: 1037 AEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACVQCSLGYRDFPDCVPCDCDLRG 1096
Query: 645 VTASFAG-----CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
+ CG V C CK+ V G CN+C+ + L+ NP GC C C+
Sbjct: 1097 TSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCS 1153
Score = 256 bits (626), Expect = 1e-66
Identities = 149/460 (32%), Positives = 205/460 (44%), Gaps = 57/460 (12%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C G +C C YYR G + +CQPC+C H C C
Sbjct: 711 CPQGYTGTSCESCLSGYYRVDGILFG--GICQPCECHGH--AAECNVHGVCIACAHNTTG 766
Query: 388 PDCSSCAYGYFDYPN------CKPCTCNLNGTEGEH---CTPTDG---LCP-CKYNYAGK 434
C C G++ P+ C+PC C L C DG +C C Y+G
Sbjct: 767 VHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGA 826
Query: 435 SCEICEDGYYS------PECKNCEC--NTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQ 485
CE C DGYY C C+C N S + CD +TG+C C G C +C
Sbjct: 827 WCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCA 886
Query: 486 AGYYN----YPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR 541
G+Y C+ C C G+ ++C +G C CK G +CDQCL GYY L
Sbjct: 887 DGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYG--LDS 944
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPD--CLSCNCDVSG 599
C PCNC GS S C+ +G+C+C+ G +CD+C+ G+Y Y D C C+C
Sbjct: 945 GHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCP--- 1001
Query: 600 SIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSV 655
+TCD + G C C + G KC+ C + + Y A C+ CNC G T C V
Sbjct: 1002 HTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGST--HHRC-DV 1058
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL-------NSLGACN 708
G CQCK + GR C C Y + + C C+C+L GT L C
Sbjct: 1059 VTGH-CQCKSKFGGRACVQCSLGYRDFPD-----CVPCDCDLRGTSGDACNLEQGLCGCV 1112
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
++G C CK++V QC++C +G + L+ ++ GC+ C C
Sbjct: 1113 EETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFC 1152
Score = 243 bits (594), Expect = 1e-62
Identities = 142/437 (32%), Positives = 190/437 (43%), Gaps = 56/437 (12%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
CEC + C SC GY+ C+PC C+ + E C G+C C +N
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE---CN-VHGVCIACAHNT 764
Query: 432 AGKSCEICEDGYYSP-------ECKNCECN-TVGSVSY--VCDKLTGD---CT-CKSKYS 477
G CE C G+Y +C+ C C T+ S ++ C GD C C YS
Sbjct: 765 TGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQ 529
G C +C GYY PT C PC+C + +E CD V+G+C+ C G C++
Sbjct: 825 GAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER 884
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYP 588
C G+Y + + C C C GS S C + G C+C N G QCDQC GYY
Sbjct: 885 CADGFYGDAV-TAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLD 943
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C CNC V+GS+ C D G CHC G +CD C FY Y +C C+C
Sbjct: 944 SGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHT 1003
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
T P C C QG C +C+ +W GC+ CNC+L G+ +
Sbjct: 1004 QNTCD-------PETGECVCPPHTQGVKCEECEDGHWGYDA--EVGCQACNCSLVGSTHH 1054
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
C+ +G C CK G R C QC G+ D C CDCD+ G+ + C+ G
Sbjct: 1055 --RCDVVTGHCQCKSKFGGRACVQCSLGY-----RDFPDCVPCDCDLRGTSGDACNLEQG 1107
Query: 764 QCHCHSRVEGRRCDQPI 780
C C C + +
Sbjct: 1108 LCGCVEETGACPCKENV 1124
Score = 241 bits (589), Expect = 4e-62
Identities = 142/453 (31%), Positives = 200/453 (44%), Gaps = 59/453 (13%)
Query: 219 FYSIKDISIGGRCM---CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQK 275
+Y + I GG C C+GHA C N++ + C HNT G C +C GF +
Sbjct: 727 YYRVDGILFGGICQPCECHGHAAEC-------NVHGVCIACAHNTTGVHCEQCLPGFYGE 779
Query: 276 KWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGI 335
R + C+PC C + P + +N E C C G
Sbjct: 780 PSRGTPG----DCQPCACPLTIASNNFSP-------TCHLNDGDE--VVCDWCAPGYSGA 826
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDC 390
C +C Y YG + C PC C DP G+C+ +G C +C C
Sbjct: 827 WCERCADGY---YGNPTVPGESCVPCDCSGNVDPS-EAGHCDSVTGECLKCLGNTDGAHC 882
Query: 391 SSCAYGYF----DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
CA G++ NC+ C C++ G+ C GLC CK N G+ C+ C GYY
Sbjct: 883 ERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL 942
Query: 447 E----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP--TCKPCNCD 500
+ C+ C C+ GSVS C G C C +G+ C++C G+Y Y +C PC+C
Sbjct: 943 DSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCP 1001
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSC 560
+ + CD +G+C+C G +C++C G++ E C CNC GST C
Sbjct: 1002 HT---QNTCDPETGECVCPPHTQGVKCEECEDGHW--GYDAEVGCQACNCSLVGSTHHRC 1056
Query: 561 S-ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNG 609
G C C + FGG C QCS GY +PDC+ C+CD+ G+ G C ++ G
Sbjct: 1057 DVVTGHCQCKSKFGGRACVQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETG 1116
Query: 610 LCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
C CK N G +C+ CRE + A C P
Sbjct: 1117 ACPCKENVFGPQCNECREGTFALRADNPLGCSP 1149
Score = 231 bits (565), Expect = 4e-59
Identities = 130/356 (36%), Positives = 170/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHY---RLPSGFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
C Y G CE+CA+G+Y +P CVPC C+G+ D CD TG CL C NT
Sbjct: 819 CAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTD 878
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G HCE C G++GDA T ++C C C + + + C L E G C+C+P G
Sbjct: 879 GAHCERCADGFYGDAV--TAKNCRACEC---HVKGSHSAVCHL-ETGL---CDCKPNVTG 929
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
+C+ C GYYG L +G C+PCNCS + D G D G C CV AG
Sbjct: 930 QQCDQCLHGYYG------LDSGHGCRPCNCSVAGSVSD-GCTDE--GQC-HCVPGVAGKR 979
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA GFY A +CT C C CD TG CVC P G KC+ C HWG +
Sbjct: 980 CDRCAHGFY--AYQDGSCTPCDCPHT-QNTCDPETGECVCPPHTQGVKCEECEDGHWGYD 1036
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
+GC CNC + S +CD G C+C G+ C QC+ G+ ++ C C+C+
Sbjct: 1037 AEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACVQCSLGYRDF--PDCVPCDCDL 1094
Query: 2029 GYSVGFMCN----------ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ G CN TG C C V G +C+ C E + + L C C
Sbjct: 1095 RGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPC 1150
Score = 185 bits (450), Expect = 3e-45
Identities = 117/344 (34%), Positives = 158/344 (45%), Gaps = 48/344 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C C Y+G +C C +GYY C+PC C E C+ V G CI C
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE---CN-VHGVCIACAHNT 764
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNCDPT---GSTSTSCSA-DGK---CN-CLTNFG 573
G C+QCL G+Y + G C PC C T + S +C DG C+ C +
Sbjct: 765 TGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
Query: 574 GAQCDQCSPGYYKYP-----DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCDT 624
GA C++C+ GYY P C+ C+C +V S CD G C C N DGA C+
Sbjct: 825 GAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER 884
Query: 625 CREQFYNYPA----CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYW 680
C + FY C C C +G S + + G LC CK V G+ C+ C Y+
Sbjct: 885 CADGFYGDAVTAKNCRACECHVKG---SHSAVCHLETG-LCDCKPNVTGQQCDQCLHGYY 940
Query: 681 NLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDV 740
L + GC CNC++AG+++ C T GQC C V ++CD+C GFY Q
Sbjct: 941 GLDSGH--GCRPCNCSVAGSVSD--GC-TDEGQCHCVPGVAGKRCDRCAHGFYAYQDGS- 994
Query: 741 FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
CT CDC N CD TG+C C +G +C++ H+
Sbjct: 995 --CTPCDCP---HTQNTCDPETGECVCPPHTQGVKCEECEDGHW 1033
Score = 138 bits (334), Expect = 3e-31
Identities = 68/199 (34%), Positives = 91/199 (45%), Gaps = 16/199 (8%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPN---CRPCHCPSTAI- 1393
R C C GS C+ G C CKPNV G+ C C GYYG + CRPC+C
Sbjct: 900 RACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSV 959
Query: 1394 ---CDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGK 1450
C D G C C V G+ CDRC + + D +C P Q C+ ++G+
Sbjct: 960 SDGCTDEGQCHCVPGVAGKRCDRCAHGFYAY------QDGSCTPCDCPHTQNTCDPETGE 1013
Query: 1451 CACRENVRGRVCDHCVPGHYAFP---DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
C C + +G C+ C GH+ + C C C+ G+T+ CD T C CK+ G+A
Sbjct: 1014 CVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRA 1073
Query: 1508 CDTCKEEYFNLQDDNPDGC 1526
C C Y + D P C
Sbjct: 1074 CVQCSLGYRDFPDCVPCDC 1092
Score = 126 bits (303), Expect = 2e-27
Identities = 112/414 (27%), Positives = 193/414 (46%), Gaps = 48/414 (11%)
Query: 2619 LQKLKDLVEQARTVANRIQVGVTFDR--WSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDG 2676
L ++K L+ QAR A I+V V+ DR QP++ T +T T +T+E D
Sbjct: 2099 LSEIKLLISQARKQAASIKVAVSADRDCIRAYQPQISST--NYNTLT---LNVKTQEPDN 2153
Query: 2677 FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNR 2736
+ YLG+ + + D++ + ++ G + D+G S + P D + DNR
Sbjct: 2154 LLFYLGS--------STASDFLAVEMRRGRVAFLWDLGSGSTRLEFP-----DFPIDDNR 2200
Query: 2737 WYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVPSDA 2796
W+ + V R G LS++E N +K + PG + +++ + ++VGG+
Sbjct: 2201 WHSIHVARFGNIGSLSVKEMSSNQKSP--TKTSKSPGTANVLDVN-NSTLMFVGGLGGQI 2257
Query: 2797 KLQ-GISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGPQEYRFDGR 2855
K + F+G + E + +GLWN++ + + R SSQ+ + FDG
Sbjct: 2258 KKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIE----REGKCRGCFGSSQNEDPSFHFDGS 2313
Query: 2856 GYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGN 2913
GY+ + L Q+++ F T++PNGL+ +G G F S+ + GRV + LG+
Sbjct: 2314 GYSVV--EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGS 2371
Query: 2914 TEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTV-------DNEVLKAESNSPSADIPSL 2966
I + T R YN+G W+K+ +R + L V + E + E+ S+D+ L
Sbjct: 2372 GP--ITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRL 2429
Query: 2967 --DTMNFGGNNKGIL---QVPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC 3015
D + GG + + V + F GC++ + I+ DL N S G+ GC
Sbjct: 2430 DKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISRSTFDLLRN--SYGVRKGC 2481
Score = 124 bits (299), Expect = 6e-27
Identities = 83/248 (33%), Positives = 112/248 (45%), Gaps = 53/248 (21%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNCDPTG--------------- 554
QC C+ G C++C GY+ Q + C CNC
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 555 -STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYK------YPD--CLSCNCDVSGSIGST 604
+T+ G C NCL N G C+ C GYY+ Y D C CNCD GS+ S
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 605 C--DD----------NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC 652
C DD G C CK + G KCD C+ + +YP C C C+P G +AS C
Sbjct: 409 CIKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVG-SASDEPC 467
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC----NLAGTLN-SLGAC 707
C CK+ V+G+ C+ CKP ++NL+E NP GC +C C ++ +L+ LG
Sbjct: 468 TGP-----CVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPLGQV 522
Query: 708 NTKSGQCV 715
N+ SG V
Sbjct: 523 NSMSGWLV 530
Score = 118 bits (285), Expect = 3e-25
Identities = 91/292 (31%), Positives = 124/292 (42%), Gaps = 66/292 (22%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ H + C +D K+L +C C+HNT G +CN+C P Y++
Sbjct: 270 CICYGHASSCPWDETT--KKL------------QC-QCEHNTCGESCNRCCPGYHQ---- 310
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNL 410
QP + S CE C C + + DC Y+D K +L
Sbjct: 311 --------QPWRPGTVSSGNTCEA----CNCHNKAK--DC------YYDESVAKQKK-SL 349
Query: 411 NGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE---------CKNCECNTVGSVS 460
N T G+ G+C C N G +CE C DGYY P C+ C C+ VGS+S
Sbjct: 350 N-TAGQF--RGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLS 406
Query: 461 YVC-----------DKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
VC K G C CK Y+G C++CQ GY +YPTC C C+ G+
Sbjct: 407 SVCIKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD-- 464
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
+ +G C+CK G CD+C G+Y R C C C +S S
Sbjct: 465 EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLS 516
Score = 117 bits (281), Expect = 9e-25
Identities = 73/219 (33%), Positives = 96/219 (43%), Gaps = 51/219 (23%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +CN+C GY+ P TC+ CNC + + V+
Sbjct: 290 CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSL 349
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYM--QVLGRERQ-CVPCNCDPTGSTSTSC 560
G CI C G C+ C+ GYY +V E + C PCNCDP GS S+ C
Sbjct: 350 NTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVC 409
Query: 561 SAD------------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD- 607
D G+C C + G +CD+C GY YP C+SC C+ +GS D+
Sbjct: 410 IKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCN---PVGSASDEP 466
Query: 608 -NGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNC 640
G C CK N +G CD C+ FYN C EC C
Sbjct: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 117 bits (281), Expect = 9e-25
Identities = 86/273 (31%), Positives = 117/273 (42%), Gaps = 47/273 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCN---GHSDQCDVNTGICLNCADNTIGD 1791
C C G C+QC G+Y L SG C PC C+ SD C + G C +C G
Sbjct: 921 CDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGC-TDEGQC-HCVPGVAGK 978
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C+ C G++ C C CP + N +CD E G C C P G +
Sbjct: 979 RCDRCAHGFYAYQD----GSCTPCDCP--HTQN----TCD-PETGE---CVCPPHTQGVK 1024
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
CE C G++G D G C+ CNCS + CD + G C +C + G AC
Sbjct: 1025 CEECEDGHWGY----DAEVG--CQACNCS--LVGSTHHRCDVVTGHC-QCKSKFGGRACV 1075
Query: 1912 LCAPGFYGDAIFSKNCTACICD-----------EFGMADCDSTTGTCVCRPGVIGEKCDR 1960
C+ G Y D +C C CD E G+ C TG C C+ V G +C+
Sbjct: 1076 QCSLG-YRDF---PDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNE 1131
Query: 1961 CAPDHWGLNTG--LGCTPCNC-GIASESTQCDD 1990
C + L LGC+PC C G++ ++ +D
Sbjct: 1132 CREGTFALRADNPLGCSPCFCSGLSHLCSELED 1164
Score = 103 bits (248), Expect = 9e-21
Identities = 115/483 (23%), Positives = 189/483 (39%), Gaps = 40/483 (8%)
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFY----------GDAIFSKNCTACICDEFGMADCDS 1942
S+ +C+ C T G +C CAPG++ G C C C+ CD
Sbjct: 1357 SLLENCV-CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT-CDP 1414
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWGLNTGLG--CTPCNCGI---ASESTQC---DDDNG 1993
TG C+ C G+ CD C ++G TG C C C AS S C D +
Sbjct: 1415 NTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDF 1474
Query: 1994 QC-RCAKGVTGKQCDQCAAGFWN--YTKDG-CDHCNCNTGYSVGFMCNAT-GQCECLPGV 2048
+C C G GK C++C++ ++ T G C C+CN SV C+ T GQC C G
Sbjct: 1475 RCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGA 1534
Query: 2049 IGEKCDRCPERWVLIPQEGCLEC-DSCTDALIFSVEDL-SALLANETMDFKDKADSFFTT 2106
G +CD C R +L+ + C+ C D C L+ ++++ A+L+ +
Sbjct: 1535 SGLRCDECEPRHILM-ETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSN 1593
Query: 2107 QRLNYISNQTELLRPKVAQ-LKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISR 2165
Q LL+ + + L + + V L+ +L S + +++
Sbjct: 1594 LENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKE 1653
Query: 2166 AAKLAEDAERTLAAVRESAREATEVVKHVAD-LATGLELSQQPKVDSALTEARQIRD-DI 2223
+ LA ER ++ E + T D L L + ++L E QIRD
Sbjct: 1654 SQDLAVAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQ 1713
Query: 2224 ADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAK--ASSHRPDLK-FESLVNATRE 2280
++ + + AE + ++ ++ + E A S H +LK E+LV
Sbjct: 1714 LHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEA 1773
Query: 2281 LKDKLDDML-----EYTDLAQHTAHTAEELNTKNRLSKFGNKVNSVTKLNTAAMGDLIDA 2335
+ + +L + + H EE N + L G + T A+ D ++
Sbjct: 1774 KMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEH 1833
Query: 2336 AYD 2338
D
Sbjct: 1834 LED 1836
Score = 103 bits (246), Expect = 2e-20
Identities = 63/209 (30%), Positives = 88/209 (42%), Gaps = 32/209 (15%)
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYN--------------YPTCKPCNCDTSGTEPSICDD 511
L +C C G +C C GY+ C PC+C+ CD
Sbjct: 1358 LLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN---NHSDTCDP 1414
Query: 512 VSGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC--DPTGSTSTSCSADG---- 564
+G+C+ C G CD C SGYY +V G C C C P S S +C +G
Sbjct: 1415 NTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDF 1474
Query: 565 KCN-CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCD-DNGLCHCKSNF 617
+C+ CL + G C++CS YY P C C+C+ GS+ CD +G C C+
Sbjct: 1475 RCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGA 1534
Query: 618 DGAKCDTCREQFYNYPA-CEECNCDPRGV 645
G +CD C + C C+ + GV
Sbjct: 1535 SGLRCDECEPRHILMETDCVSCDDECVGV 1563
Score = 101 bits (243), Expect = 4e-20
Identities = 69/219 (31%), Positives = 89/219 (40%), Gaps = 30/219 (13%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP------NCRPCHCPST 1391
+PC C + ECN G C N G C C G+YG P +C+PC CP T
Sbjct: 740 QPCECHGHAA---ECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLT 796
Query: 1392 AICD-----------DNGMC-ICPKNVEGENCDRCKP-YTFNFDVQ-RGCDDCNCNPLGV 1437
+ D +C C G C+RC Y N V C C+C+
Sbjct: 797 IASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVD 856
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHY----AFPDCYQCTCNRHGTTYDVCDQ 1492
C++ +G+C C N G C+ C G Y +C C C+ G+ VC
Sbjct: 857 PSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHL 916
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T C CK NV GQ CD C Y+ L D+ GC C C
Sbjct: 917 ETGLCDCKPNVTGQQCDQCLHGYYGL--DSGHGCRPCNC 953
Score = 100 bits (240), Expect = 9e-20
Identities = 58/171 (33%), Positives = 80/171 (46%), Gaps = 27/171 (15%)
Query: 403 CKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYY------SPECKNCEC-- 453
C PC+CN + C P G C C N AG C++C GYY + +C C C
Sbjct: 1400 CVPCSCN---NHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPH 1456
Query: 454 NTVGSVSYVCDKLTGD----C-TCKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSG 503
+ S S C L GD C C Y G+ C +C + YY P +C+ C+C+ G
Sbjct: 1457 SPPASFSPTC-VLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHG 1515
Query: 504 TEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+ CD SGQC+C+ G G RCD+C + + E CV C+ + G
Sbjct: 1516 SVHGDCDRTSGQCVCRLGASGLRCDECEPRHILM----ETDCVSCDDECVG 1562
Score = 100 bits (239), Expect = 1e-19
Identities = 77/264 (29%), Positives = 103/264 (39%), Gaps = 34/264 (12%)
Query: 1765 CQCNGHSDQC---DVNTGICLNCADNTIGDHCEFCMSGYHGD----ATVGTPRDCLICAC 1817
C C GH+ C + + C NT G+ C C GYH TV + C C C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 1818 PMP----YPSNNFA-----LSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDL 1868
Y + A L+ G + NC G CE C GYY P
Sbjct: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYR-PHKVSP 388
Query: 1869 HTGDYCKPCNCS--GNINP---QDPGSCDSIN----GDCLKCVNNTAGAACNLCAPGFYG 1919
+ + C+PCNC G+++ +D D N G C C G C+ C G Y
Sbjct: 389 YEDEPCRPCNCDPVGSLSSVCIKDDLHSDLENGKQPGQC-PCKEGYTGEKCDRCQLG-YK 446
Query: 1920 DAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGL--NTGLGCTPC 1977
D C +C C+ G A + TG CVC+ V G+ CDRC P + L GC+ C
Sbjct: 447 D---YPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC 503
Query: 1978 NC-GIASESTQCDDDNGQCRCAKG 2000
C G++ + GQ G
Sbjct: 504 FCFGVSDVCSSLSWPLGQVNSMSG 527
Score = 97.5 bits (232), Expect = 8e-19
Identities = 64/205 (31%), Positives = 88/205 (42%), Gaps = 21/205 (10%)
Query: 1784 CADNTIGDHCEFCMSGYH-GDATVGTPRDC--LICACPMPYPSNNFALSCDLSENGSLIS 1840
C T+G C+ C GYH G G+ R L+ C +P NN + +CD + L
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPC-VPCSCNNHSDTCDPNTGKCL-- 1420
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--- 1897
NC G C+ C +GYYG + C C C + +C + GD
Sbjct: 1421 -NCGDNTAGDHCDVCTSGYYGKVTGS----ASDCALCACPHSPPASFSPTC-VLEGDHDF 1474
Query: 1898 -CLKCVNNTAGAACNLCAPGFYGDAIF-SKNCTACICDEFGMA--DCDSTTGTCVCRPGV 1953
C C+ G C C+ +YG+ +C C C+ G DCD T+G CVCR G
Sbjct: 1475 RCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGA 1534
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCN 1978
G +CD C P H + T C C+
Sbjct: 1535 SGLRCDECEPRHILMET--DCVSCD 1557
Score = 93.5 bits (222), Expect = 1e-17
Identities = 63/213 (29%), Positives = 91/213 (42%), Gaps = 33/213 (15%)
Query: 328 CQHNTEGINCNKCRPTYYR---PYGKRWDELDV---CQPCQCDPHFSTGNCEEESGRC-E 380
C T G +C C P Y+R P G + C PC C+ H T C+ +G+C
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT--CDPNTGKCLN 1421
Query: 381 CRPEFQPPDCSSCAYGYF-----DYPNCKPCTC------NLNGT---EGEHCTPTDGLCP 426
C C C GY+ +C C C + + T EG+H D
Sbjct: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA--- 1478
Query: 427 CKYNYAGKSCEICEDGYY-SPE-----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRT 480
C Y GK CE C YY +P+ C+ C+CN GSV CD+ +G C C+ SG
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
Query: 481 CNQCQAGYYNYPT-CKPCNCDTSGTEPSICDDV 512
C++C+ + T C C+ + G + D++
Sbjct: 1539 CDECEPRHILMETDCVSCDDECVGVLLNDLDEI 1571
Score = 91.5 bits (217), Expect = 5e-17
Identities = 72/260 (27%), Positives = 104/260 (40%), Gaps = 41/260 (15%)
Query: 237 ADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRI-SQNWDR---FSCEPCN 292
A+ P + +L + C C T G C C G+ + K S R C PC+
Sbjct: 1346 AEKLHPEEEVASL-LENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCS 1404
Query: 293 CHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRW 352
C+NH+ C DP GKCLNC NT G +C+ C YY GK
Sbjct: 1405 CNNHSDTC--DPNT----------------GKCLNCGDNTAGDHCDVCTSGYY---GKVT 1443
Query: 353 DELDVCQPCQCD---PHFSTGNCEEESG---RCE-CRPEFQPPDCSSCAYGYFDYP---- 401
C C C P + C E RC+ C ++ C C+ Y+ P
Sbjct: 1444 GSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPG 1503
Query: 402 -NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY--YSPECKNCECNTVGS 458
+C+ C CN +G+ C T G C C+ +G C+ CE + +C +C+ VG
Sbjct: 1504 GSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDECVGV 1563
Query: 459 VSYVCDKLTGDCTCKSKYSG 478
+ D++ GD +G
Sbjct: 1564 LLNDLDEI-GDAVLSLNLTG 1582
Score = 90.6 bits (215), Expect = 9e-17
Identities = 65/224 (29%), Positives = 89/224 (39%), Gaps = 32/224 (14%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPE---------------CKNCECNTVGSVSYVCDKLTGD 469
C C G SC+ C GY+ + C C CN + S CD TG
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN---NHSDTCDPNTGK 1418
Query: 470 C-TCKSKYSGRTCNQCQAGYYNYPT-----CKPCNCDTS---GTEPSIC--DDVSGQC-I 517
C C +G C+ C +GYY T C C C S P+ D +C
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 518 CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQ 576
C G+ G C++C S YY C C+C+P GS C G+C C G +
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
Query: 577 CDQCSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDG 619
CD+C P + DC+SC+ + G + + D+ G N G
Sbjct: 1539 CDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTG 1582
Score = 90.6 bits (215), Expect = 9e-17
Identities = 68/219 (31%), Positives = 99/219 (45%), Gaps = 37/219 (16%)
Query: 516 CICKAGFGGPRCDQCLSGYYMQVL--GRER-------QCVPCNCDPTGSTSTSCSAD-GK 565
C+C G G C C GY+ L G +R CVPC+C+ + S +C + GK
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN---NHSDTCDPNTGK 1418
Query: 566 C-NCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVS--GSIGSTC----DDNGLCH- 612
C NC N G CD C+ GYY DC C C S S TC D + C
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 613 CKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
C ++G C+ C +Y P +C++C+C+P G S G +G+ C C+
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHG---SVHGDCDRTSGQ-CVCRLGA 1534
Query: 668 QGRICNDCKPLYWNLQEYNPFGC-EQCNCNLAGTLNSLG 705
G C++C+P + L E + C ++C L L+ +G
Sbjct: 1535 SGLRCDECEPRH-ILMETDCVSCDDECVGVLLNDLDEIG 1572
Score = 89.0 bits (211), Expect = 3e-16
Identities = 44/111 (39%), Positives = 55/111 (49%), Gaps = 16/111 (14%)
Query: 1338 RPCLCDFMGS-----------TELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPC 1386
RPC CD +GS ++LE GQCPCK G C C+ GY +P C C
Sbjct: 395 RPCNCDPVGSLSSVCIKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSC 454
Query: 1387 HCPSTAICDD---NGMCICPKNVEGENCDRCKPYTFNFDVQ--RGCDDCNC 1432
C D G C+C +NVEG+ CDRCKP +N + RGC +C C
Sbjct: 455 GCNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 86.2 bits (204), Expect = 2e-15
Identities = 66/226 (29%), Positives = 97/226 (42%), Gaps = 51/226 (22%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD----------------VS 598
+C C N G C++C PGY++ P C +CNC S
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFYN------YP--ACEECNCDPRGVTASF 649
+ G+C +C N G C+TC + +Y Y C CNCDP G +S
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 650 AGCGSVPA----GEL---CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
+ + G+ C CK+ G C+ C+ Y ++Y C C CN G+ +
Sbjct: 409 CIKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGY---KDYPT--CVSCGCNPVGSAS 463
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C +G CVCK++V + CD+C GFY L+ + GC+EC C
Sbjct: 464 D-EPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 85.0 bits (201), Expect = 5e-15
Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 34/219 (15%)
Query: 566 CNCLTNFGGAQCDQCSPGYY--KYP------------DCLSCNCDVSGSIGSTCDDN-GL 610
C C G C C+PGY+ K P C+ C+C+ + TCD N G
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN---NHSDTCDPNTGK 1418
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C +C N G CD C +Y C C C P ASF+ + +C
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCAC-PHSPPASFSPTCVLEGDHDFRCD 1477
Query: 665 DRV---QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVG 721
+ +G+ C C Y+ + C++C+CN G+++ G C+ SGQCVC+
Sbjct: 1478 ACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVH--GDCDRTSGQCVCRLGAS 1535
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDK 760
+CD+C ++T+ C CD + G + N+ D+
Sbjct: 1536 GLRCDECEPRHILMETD----CVSCDDECVGVLLNDLDE 1570
Score = 83.0 bits (196), Expect = 2e-14
Identities = 66/234 (28%), Positives = 96/234 (41%), Gaps = 51/234 (21%)
Query: 1900 KCVNNTAGAACNLCAPGFY------GDAIFSKNCTACICDEFGMADC--DSTT------- 1944
+C +NT G +CN C PG++ G C AC C DC D +
Sbjct: 291 QCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAK-DCYYDESVAKQKKSL 349
Query: 1945 ---------GTCV-CRPGVIGEKCDRCAPDHWGLNT-----GLGCTPCNCG-IASESTQC 1988
G C+ C +G C+ C ++ + C PCNC + S S+ C
Sbjct: 350 NTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVC 409
Query: 1989 DDDN-----------GQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN-TGYSVGFMC 2036
D+ GQC C +G TG++CD+C G+ +Y C C CN G + C
Sbjct: 410 IKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT--CVSCGCNPVGSASDEPC 467
Query: 2037 NATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLA 2090
TG C C V G+ CDRC + + ++ C C F V D+ + L+
Sbjct: 468 --TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC---FCFGVSDVCSSLS 516
Score = 74.1 bits (174), Expect = 9e-12
Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 25/164 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H+DTC+P + LN C NT G C+ C SG+ K + + C
Sbjct: 1403 CSCNNHSDTCDP-NTGKCLN-----CGDNTAGDHCDVCTSGYYGKVTGSASD-----CAL 1451
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C H+ ++ P + + G ++ +C C EG +C +C +Y YG
Sbjct: 1452 CAC-PHSPPASFSP-------TCVLEGDHD--FRCDACLLGYEGKHCERCSSSY---YGN 1498
Query: 351 RWDELDVCQPCQCDPHFST-GNCEEESGRCECRPEFQPPDCSSC 393
CQ C C+PH S G+C+ SG+C CR C C
Sbjct: 1499 PQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDEC 1542
Score = 67.7 bits (158), Expect = 7e-10
Identities = 42/180 (23%), Positives = 65/180 (36%), Gaps = 12/180 (6%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQ-------- 662
C C G C C ++ + PR + A C + C
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG---QC-VCKQ 718
C D G C+ C Y+ + C C C + + C + +C C
Sbjct: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLL 1481
Query: 719 HVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
+ C++C +Y C +CDC+ GS+ +CD+T+GQC C G RCD+
Sbjct: 1482 GYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE 1541
Score = 65.3 bits (152), Expect = 4e-09
Identities = 83/338 (24%), Positives = 143/338 (42%), Gaps = 37/338 (10%)
Query: 2871 NQVLLFFRTYAPNGLIYLVGEG--GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
N + L +T P+ L++ +G F ++ M+ GRV LG+ + +D
Sbjct: 2140 NTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDF-PIDD 2198
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPS----LDTMN--------FGGNNK 2976
+WH + RF SL+V +S + ++ P LD N GG K
Sbjct: 2199 NRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIK 2258
Query: 2977 GILQVPDRGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL-----VSFNGTDSYLR 3031
V F GC+ + +NG ++ L +E G GC +S F+G+ +
Sbjct: 2259 KSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVV 2318
Query: 3032 FVDVTSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLDT 3091
+ + Q+ + F T PNGLL +Y+ T D +S+ L G++ V++
Sbjct: 2319 EKSLPATVTQIIMLFNTFSPNGLL-LYLGSYGT---KDFLSIELFRGRVKVMTDLGSGPI 2374
Query: 3092 GLNT---YNDSQWHVLTVTHN-TSALKLVVDDFDYFSTDT-------APPPLHILD-GVL 3139
L T YN+ W+ + N + V+D ++ + +T A L+ LD +
Sbjct: 2375 TLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPI 2434
Query: 3140 FIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLL 3177
++GG+ VV + +K F GCI + I+ +LL
Sbjct: 2435 YVGGLPRSRVVRRGVTTK-SFVGCIKNLEISRSTFDLL 2471
Score = 53.6 bits (123), Expect = 1e-05
Identities = 76/347 (21%), Positives = 140/347 (40%), Gaps = 34/347 (9%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYN 3391
LT++ +T + ++FY S+ + FLA MR ++ ++++ G G T + +
Sbjct: 2142 LTLNVKT-QEPDNLLFYLGSSTASD---FLAVEMRRGRVAFLWDLGSGSTRLEFPDFPID 2197
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSVT--CNTP-------LSLAPPYYYGGLRYVN 3442
D WH++ + R G G L+V + S T +P ++ + + GGL
Sbjct: 2198 DNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGL---G 2254
Query: 3443 ERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNY 3502
+I K F GCL +NG+ + +C + S + +
Sbjct: 2255 GQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSG 2314
Query: 3503 LKLLENFKVGDEVSISMEVRPRNTTGLLLSV--HGKKDYMVLELLDSEVVANVENGNGPF 3560
++E I M + GLLL + +G KD++ +EL V + G+GP
Sbjct: 2315 YSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPI 2374
Query: 3561 RATYKLSNKHYLCDGNWHKI------HXXXXXXXXXXXXDGHFSKPGIGAYTSTDTH--- 3611
L+++ Y +G W+KI +K G S+D +
Sbjct: 2375 TL---LTDRRY-NNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLD 2430
Query: 3612 -SALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVG 3657
+Y+GG R RGV + + F GC++N+ + + + ++ G
Sbjct: 2431 KDPIYVGGLPRSRVVRRGV-TTKSFVGCIKNLEISRSTFDLLRNSYG 2476
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/100 (29%), Positives = 37/100 (37%), Gaps = 15/100 (15%)
Query: 659 ELCQCKDRVQGRICNDCKPLY--WNLQEYNPFG-------CEQCNCNLAGTLNSLGACNT 709
E C C G C DC P Y L + G C C+CN N C+
Sbjct: 1360 ENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN-----NHSDTCDP 1414
Query: 710 KSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
+G+C+ C + CD C G+Y T C C C
Sbjct: 1415 NTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCAC 1454
>U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain protein.
Length = 3110
Score = 517 bits (1275), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPRPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 207 bits (505), Expect = 7e-52
Identities = 312/1412 (22%), Positives = 536/1412 (37%), Gaps = 139/1412 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++ + +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANIYIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD 3090
V + ++ L F T +G+ + + T P V++ R +L+
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGI--ILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLE 2596
Query: 3091 TGLNT----------------YNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLH 3133
L+T ++D + H + V + VD+ Y T P+
Sbjct: 2597 VHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIE 2656
Query: 3134 ILDGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG-- 3191
+ LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2657 VKK--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQ 2713
Query: 3192 --TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2714 KLREDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 110 bits (264), Expect = 1e-22
Identities = 92/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
+ N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 AAI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFATTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 55.2 bits (127), Expect = 4e-06
Identities = 69/309 (22%), Positives = 125/309 (40%), Gaps = 36/309 (11%)
Query: 2696 DYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRE 2755
D+ + ++NG PY D+G P +++ D +W+++ + R + L +
Sbjct: 2812 DFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN------DGQWHKIKIMRSKQEGILYVDG 2865
Query: 2756 SLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVPSDAKLQGISFPAF--EGQIEEL 2813
+ + TI K+AD+ LD LYVGG+P + + I + +G + L
Sbjct: 2866 ASNR---TISPKKADI--------LDVV-GMLYVGGLPINYTTRRIGPVTYSIDGCVRNL 2913
Query: 2814 MIGDTPVGLWNFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQV 2873
+ + P L S+ + ++Q G FDG G+A G G+ V
Sbjct: 2914 HMAEAPADLEQPTSSFHVGTC-----FANAQRGTY---FDGTGFAKAVG-GFKVGLDLLV 2964
Query: 2874 LLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGK 2930
F T G++ + G ++ + ++ G + G DG+
Sbjct: 2965 EFEFATTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQ 3024
Query: 2931 WHKLDARRFLAKCSLTVDNEVLKAESNSP-SADIPSLDTMNFGGNNKGILQ---VPDRGF 2986
WHK+ A + + LTVD ++A+S +P S + D + GG + Q F
Sbjct: 3025 WHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPF 3084
Query: 2987 DGCMRQISI 2995
GC+R + +
Sbjct: 3085 RGCIRSLKL 3093
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 48.4 bits (110), Expect = 5e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMAAINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKFK 3047
R + + DL + S + G FA+ F+GT + + V L ++F+
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3048 --TAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FATTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.7 bits (91), Expect = 0.097
Identities = 42/177 (23%), Positives = 66/177 (37%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLL--LSVHGKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL ++ D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMAAINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)
protein.
Length = 3110
Score = 516 bits (1274), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 208 bits (508), Expect = 3e-52
Identities = 312/1412 (22%), Positives = 537/1412 (38%), Gaps = 139/1412 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++++ +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD 3090
V + ++ L F T +G+ + + T P V++ R +L+
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGI--ILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLE 2596
Query: 3091 TGLNT----------------YNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLH 3133
L+T ++D + H + V + VD+ Y T P+
Sbjct: 2597 VHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIE 2656
Query: 3134 ILDGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG-- 3191
+ LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2657 VKK--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQ 2713
Query: 3192 --TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2714 KLREDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 110 bits (264), Expect = 1e-22
Identities = 92/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
+ N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 AAI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFATTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 55.2 bits (127), Expect = 4e-06
Identities = 69/309 (22%), Positives = 125/309 (40%), Gaps = 36/309 (11%)
Query: 2696 DYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRE 2755
D+ + ++NG PY D+G P +++ D +W+++ + R + L +
Sbjct: 2812 DFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN------DGQWHKIKIMRSKQEGILYVDG 2865
Query: 2756 SLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVPSDAKLQGISFPAF--EGQIEEL 2813
+ + TI K+AD+ LD LYVGG+P + + I + +G + L
Sbjct: 2866 ASNR---TISPKKADI--------LDVV-GMLYVGGLPINYTTRRIGPVTYSIDGCVRNL 2913
Query: 2814 MIGDTPVGLWNFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQV 2873
+ + P L S+ + ++Q G FDG G+A G G+ V
Sbjct: 2914 HMAEAPADLEQPTSSFHVGTC-----FANAQRGTY---FDGTGFAKAVG-GFKVGLDLLV 2964
Query: 2874 LLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGK 2930
F T G++ + G ++ + ++ G + G DG+
Sbjct: 2965 EFEFATTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQ 3024
Query: 2931 WHKLDARRFLAKCSLTVDNEVLKAESNSP-SADIPSLDTMNFGGNNKGILQ---VPDRGF 2986
WHK+ A + + LTVD ++A+S +P S + D + GG + Q F
Sbjct: 3025 WHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPF 3084
Query: 2987 DGCMRQISI 2995
GC+R + +
Sbjct: 3085 RGCIRSLKL 3093
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 48.4 bits (110), Expect = 5e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMAAINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKFK 3047
R + + DL + S + G FA+ F+GT + + V L ++F+
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3048 --TAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FATTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.7 bits (91), Expect = 0.097
Identities = 42/177 (23%), Positives = 66/177 (37%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLL--LSVHGKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL ++ D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMAAINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 516 bits (1274), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 207 bits (505), Expect = 7e-52
Identities = 311/1410 (22%), Positives = 538/1410 (38%), Gaps = 135/1410 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++++ +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVS-------RTQTAIMPDSISLSLVNGKLVV- 3082
V + ++ L F T +G++ + R + ++ L G+L V
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVH 2598
Query: 3083 ------VSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLHIL 3135
++ + N ++D + H + V + VD+ Y T P+ +
Sbjct: 2599 LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK 2658
Query: 3136 DGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG---- 3191
LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2659 K--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKL 2715
Query: 3192 TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2716 REDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 2794 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 2843
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 2844 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 2887
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 2888 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 2942
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 2943 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 2998
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 2999 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 3058
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 3059 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 3093
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 516 bits (1274), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 207 bits (505), Expect = 7e-52
Identities = 311/1410 (22%), Positives = 538/1410 (38%), Gaps = 135/1410 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++++ +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVS-------RTQTAIMPDSISLSLVNGKLVV- 3082
V + ++ L F T +G++ + R + ++ L G+L V
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVH 2598
Query: 3083 ------VSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLHIL 3135
++ + N ++D + H + V + VD+ Y T P+ +
Sbjct: 2599 LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK 2658
Query: 3136 DGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG---- 3191
LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2659 K--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKL 2715
Query: 3192 TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2716 REDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 2794 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 2843
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 2844 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 2887
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 2888 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 2942
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 2943 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 2998
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 2999 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 3058
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 3059 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 3093
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 516 bits (1274), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 207 bits (505), Expect = 7e-52
Identities = 311/1410 (22%), Positives = 538/1410 (38%), Gaps = 135/1410 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++++ +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVS-------RTQTAIMPDSISLSLVNGKLVV- 3082
V + ++ L F T +G++ + R + ++ L G+L V
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVH 2598
Query: 3083 ------VSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLHIL 3135
++ + N ++D + H + V + VD+ Y T P+ +
Sbjct: 2599 LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK 2658
Query: 3136 DGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG---- 3191
LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2659 K--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKL 2715
Query: 3192 TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2716 REDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 2794 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 2843
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 2844 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 2887
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 2888 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 2942
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 2943 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 2998
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 2999 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 3058
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 3059 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 3093
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 516 bits (1274), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 207 bits (505), Expect = 7e-52
Identities = 311/1410 (22%), Positives = 538/1410 (38%), Gaps = 135/1410 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++++ +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVS-------RTQTAIMPDSISLSLVNGKLVV- 3082
V + ++ L F T +G++ + R + ++ L G+L V
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVH 2598
Query: 3083 ------VSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLHIL 3135
++ + N ++D + H + V + VD+ Y T P+ +
Sbjct: 2599 LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK 2658
Query: 3136 DGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG---- 3191
LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2659 K--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKL 2715
Query: 3192 TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2716 REDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 2794 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 2843
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 2844 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 2887
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 2888 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 2942
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 2943 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 2998
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 2999 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 3058
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 3059 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 3093
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 516 bits (1274), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 207 bits (505), Expect = 7e-52
Identities = 311/1410 (22%), Positives = 538/1410 (38%), Gaps = 135/1410 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++++ +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVS-------RTQTAIMPDSISLSLVNGKLVV- 3082
V + ++ L F T +G++ + R + ++ L G+L V
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVH 2598
Query: 3083 ------VSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLHIL 3135
++ + N ++D + H + V + VD+ Y T P+ +
Sbjct: 2599 LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK 2658
Query: 3136 DGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG---- 3191
LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2659 K--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKL 2715
Query: 3192 TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2716 REDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 2794 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 2843
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 2844 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 2887
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 2888 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 2942
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 2943 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 2998
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 2999 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 3058
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 3059 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 3093
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 516 bits (1274), Expect = e-145
Identities = 290/800 (36%), Positives = 409/800 (51%), Gaps = 86/800 (10%)
Query: 1340 CLC-DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC 1388
C+C + L+ T +C C+ N G +C C G++ P C C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 1389 PSTAI-C--DDN-----------------GMCI-CPKNVEGENCDRC-----KPYTFNFD 1422
A C D+N G+CI C +N G NC+ C +P + +
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADS---------GKCACRENVRGRVCDHCVPGHYAFP 1473
R C C+C+P+G + N++ C D G C C+ G CD C G+ +P
Sbjct: 407 YPRPCQPCHCDPIGSL-NEV-CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
DC C C+ G+ + D C CK NV G C CK +FNLQ+DN GC +CFC G
Sbjct: 465 DCKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Query: 1534 KTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED-VPELTNVTVLTVGLNDGVTN 1592
+ RC SSY+T+ I +M WY D + I + P +D + +++ + +
Sbjct: 523 VSNRCQSSYWTYGKIQDMSGWYLTD--LPGRIRVAPQQDDLDSPQQISISNAEARQALPH 580
Query: 1593 GKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRG---DGDAVAAPDVIIAGPNGYLVHNS 1649
Y+ AP YLG +L + GG LT+T+ Y D + V +I+ G N + +
Sbjct: 581 SY--YWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEG-NDLSISTA 637
Query: 1650 VEQPPVGMPWTHS-VKLSEEEFSTLDGA--PVTRDQFMHALVNISGLYIRASYWEYSIET 1706
++ + H+ V L +EE T+ G PV R +FM L N+ + ++ +Y + ++
Sbjct: 638 QDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY-SFGMDA 696
Query: 1707 --SLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS----G 1760
LS+V LE V Y + A +VE CQCP Y G SCE C H R+ G
Sbjct: 697 IFRLSSVNLESAVSYPTDGSI----AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGG 752
Query: 1761 FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C PCQC GH++ CD TG CLNC D+T G +C+ C+ G++G+ T GT DC CACP+
Sbjct: 753 ICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS 1880
PSNNF+ +C L + LI C GY G RCE CA GY+G P G C+PC C+
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS----VPGGSCQPCQCN 868
Query: 1881 GNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD- 1939
N++ PGSCDS++G CL C T G C LCA G++GDA+ +KNC C C+ G
Sbjct: 869 DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSE 928
Query: 1940 -CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRC 1997
C S TG C CR V G++CD+C +GL + GC PCNC S+S C +++GQC C
Sbjct: 929 VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDC-EESGQCWC 987
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
GVTGK+CD+CA G++N+ + GC C C+ +G C+ TG+C C P IGEKC +C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECS---HLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Query: 2057 -PERWVLIPQEGCLECDSCT 2075
P W GC C+ T
Sbjct: 1045 APNTWGHSITTGCKACNCST 1064
Score = 388 bits (954), Expect = e-106
Identities = 204/478 (42%), Positives = 267/478 (55%), Gaps = 46/478 (9%)
Query: 34 CDICDAN--NEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVK 91
C IC+ N N ++HP A+D + TWWQSP + G++Y+ V +T+DL Q F +AYV VK
Sbjct: 83 CRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVK 142
Query: 92 MGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFG---KESLQPITKDDSVICST 148
NSPRP W+LE+S D +KPWQY + + +C + + KDD VIC++
Sbjct: 143 AANSPRPGNWILERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTS 201
Query: 149 EYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YSKI PLE+GEI ISL+N RPS++ S L E+T A +RLR R + L LM A
Sbjct: 202 FYSKIHPLENGEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFA 259
Query: 209 RQDPT-----VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGP 263
+DP VTRRY+YS+KDIS+GG C+C GHA C P DPA N + C C+HNTCG
Sbjct: 260 HKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARAC-PLDPATNKSR--CECEHNTCGD 316
Query: 264 QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG 323
C++CC GF QK WR + CE CNCH EC YD + + LSL+I G+Y GGG
Sbjct: 317 SCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGG 376
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEES------ 376
C+NC NT GINC C ++RP G + CQPC CDP S C ++
Sbjct: 377 VCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRG 436
Query: 377 ---GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
G C C+ F C CA GY YP+CK C C+ G++ E P G C CK N G
Sbjct: 437 LAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--DPCFGPCICKENVEG 494
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C C+ G+++ + E N G CD +C C SG N+CQ+ Y+ Y
Sbjct: 495 GDCSRCKSGFFNLQ----EDNWKG-----CD----ECFC----SG-VSNRCQSSYWTY 534
Score = 374 bits (921), Expect = e-102
Identities = 220/632 (34%), Positives = 299/632 (47%), Gaps = 62/632 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+ F + S G PC C+ GS +C GQC C+P V G+ C C GY+ F
Sbjct: 951 CKAGTFGLQSA--RGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 1382 N--CRPCHCPSTAI-CDDN-GMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
C C C CD G CICP N GE C +C P T+ + GC CNC+ +G
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS 1067
Query: 1438 VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNT--- 1494
+ QC ++G+C C G C C GH+ +P C C C GT CD T
Sbjct: 1068 L--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKC 1125
Query: 1495 ------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSS---YYTW 1545
QC CK NV G CD C+ F L NP GC+ C+CFG TT+CS + TW
Sbjct: 1126 SCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTW 1185
Query: 1546 AAIDEMVDWYP-VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYY 1604
+ P VD + +T PE+ V + L + + Y+ PE +
Sbjct: 1186 VTLKAEQTILPLVDEALQHTTTKGIVFQHPEI----VAHMDLMREDLHLEPFYWKLPEQF 1241
Query: 1605 LGKRLTSYGGYLTYTVHYTTRGD-GDAVAAPDVIIAG---PNGYLVHNSVEQPPVGMPWT 1660
GK+L +YGG L Y +++ R + G + P VII G + ++ + P +G
Sbjct: 1242 EGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTR 1301
Query: 1661 HSVKLSEEEFSTLDGAP-----VTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEI 1715
H ++++E+E+ P VTR+ F+ L +I + I+A+Y + ++ +S + +E+
Sbjct: 1302 HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPS-----------GFCVP 1764
+ G + A +E+C CP Y GLSCE C G YRL S G CVP
Sbjct: 1362 A-EQGRGTTMTPP-ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP 1419
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN 1824
CQCNGHS CD T IC NC +T GD CE C GY+G G P DC CACP+ SN
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSN 1478
Query: 1825 NFALSCDLSENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--G 1881
NF+ SC ++E C C GY G CE CA GY G P + G C+ C C G
Sbjct: 1479 NFSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG----NPGGSCQECECDPYG 1533
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
++ P CD + G C C G C+ C
Sbjct: 1534 SL----PVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 258 bits (633), Expect = 2e-67
Identities = 151/481 (31%), Positives = 217/481 (45%), Gaps = 58/481 (12%)
Query: 308 EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHF 367
E +S +G + C G +C C P + R G + +C+PCQC H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQCFGHA 763
Query: 368 STGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE---- 416
+ C++ +G C C+ P C C G++ P +C+PC C LN
Sbjct: 764 ES--CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 417 -HCTPTDGL-CP-CKYNYAGKSCEICEDGYYSP------ECKNCECNTV--GSVSYVCDK 465
H + GL C C Y G CE C +GY+ C+ C+CN S+ CD
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 466 LTGDCT-CKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
L+G C CK +GR C C GY+ + C+PC C+ G+ +C +GQC C+A
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G RCD+C +G + L R CVPCNC+ GS S C G+C C G +CD+C
Sbjct: 942 NVQGQRCDKCKAGTFG--LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRC 999
Query: 581 SPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNY---PA 634
+ GY+ + + C +C C +G+ CD G C C N G KC C + +
Sbjct: 1000 AHGYFNFQEGGCTACEC---SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C+ CNC G + F C +V G+ C C + G C +C +WN C C+
Sbjct: 1057 CKACNCSTVG-SLDFQ-C-NVNTGQ-CNCHPKFSGAKCTECSRGHWNYPR-----CNLCD 1107
Query: 695 CNLAGT-------LNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
C L GT +C+ ++GQC CK +V CD+C G + L + GC+ C
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Query: 748 C 748
C
Sbjct: 1168 C 1168
Score = 244 bits (596), Expect = 6e-63
Identities = 143/440 (32%), Positives = 202/440 (45%), Gaps = 58/440 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C GHA++C+ D G C+ +T GP C+KC GF + + + C+P
Sbjct: 757 CQCFGHAESCD--DVTGEC----LNCKDHTGGPYCDKCLPGFYGEPTKGTSE----DCQP 806
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + + P R SL G C C G C +C Y +G+
Sbjct: 807 CACPLNIPSNNFSPTCHLDR-SL--------GLICDGCPVGYTGPRCERCAEGY---FGQ 854
Query: 351 RWDELDVCQPCQCDPH--FS-TGNCEEESGRC-ECRPEFQPPDCSSCAYGYF----DYPN 402
CQPCQC+ + FS G+C+ SG C C+P C CA GYF D N
Sbjct: 855 PSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN 914
Query: 403 CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGS 458
C+PC CN G+ E C G C C+ N G+ C+ C+ G + + C C CN+ GS
Sbjct: 915 CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGS 974
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
S+ C++ +G C C+ +G+ C++C GY+N+ C C C G CD +G+C
Sbjct: 975 KSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN---CDPKTGRC 1030
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGA 575
IC G +C +C + + C CNC GS C+ + G+CNC F GA
Sbjct: 1031 ICPPNTIGEKCSKCAPNTWGHSI--TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTC----------DDNGLCHCKSNFDGAKCDTC 625
+C +CS G++ YP C C+C + G+ +TC D G C CK N +G CD C
Sbjct: 1089 KCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Query: 626 REQFYNYPA-----CEECNC 640
R + A C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
Score = 229 bits (559), Expect = 2e-58
Identities = 129/356 (36%), Positives = 169/356 (47%), Gaps = 43/356 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS---GFCVPCQCNGHSD-----QCDVNTGICLNCADNTI 1789
CP Y G CE+CAEG++ PS G C PCQCN + D CD +G CL C T
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G +CE C GY GDA ++C C C +F+ C S+ G C C+ G
Sbjct: 895 GRYCELCADGYFGDAV--DAKNCQPCRCNA---GGSFSEVCH-SQTGQ---CECRANVQG 945
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
RC+ C AG +G L + C PCNC N C+ +G C C G
Sbjct: 946 QRCDKCKAGTFG------LQSARGCVPCNC--NSFGSKSFDCEE-SGQCW-CQPGVTGKK 995
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C+ CA G++ CTAC C G +CD TG C+C P IGEKC +CAP+ WG +
Sbjct: 996 CDRCAHGYFN--FQEGGCTACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC CNC + S QC+ + GQC C +G +C +C+ G WNY + C+ C+C
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--CNLCDCFL 1110
Query: 2029 GYSVGFMCNA----------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ C++ TGQC C V G CDRC + + L C SC
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 217 bits (531), Expect = 5e-55
Identities = 136/444 (30%), Positives = 185/444 (41%), Gaps = 64/444 (14%)
Query: 379 CECRPEFQPPDCSSC------AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C+C P + C SC G C+PC C E C G C CK +
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCF---GHAESCDDVTGECLNCKDHT 780
Query: 432 AGKSCEICEDGYY-------SPECKNCEC------NTVGSVSYVCDKLTGDCT-CKSKYS 477
G C+ C G+Y S +C+ C C N ++ L C C Y+
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 478 GRTCNQCQAGYYNYPT-----CKPCNCDTS--GTEPSICDDVSGQC-ICKAGFGGPRCDQ 529
G C +C GY+ P+ C+PC C+ + + P CD +SG C ICK G G C+
Sbjct: 841 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYYKYP 588
C GY+ + + C PC C+ GS S C S G+C C N G +CD+C G +
Sbjct: 901 CADGYFGDAVDA-KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Query: 589 D---CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPR 643
C+ CNC+ GS C+++G C C+ G KCD C ++N+ C C C
Sbjct: 960 SARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC--- 1016
Query: 644 GVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S G P C C G C+ C P W GC+ CNC+ G+L+
Sbjct: 1017 ----SHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF 1070
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT- 762
CN +GQC C +C +C G + C CDC + G+ CD T
Sbjct: 1071 --QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETK 1123
Query: 763 --------GQCHCHSRVEGRRCDQ 778
GQC C VEG CD+
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 207 bits (505), Expect = 7e-52
Identities = 311/1410 (22%), Positives = 538/1410 (38%), Gaps = 135/1410 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 1441
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 1442 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 1501
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 1502 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 1560
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 1561 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 1620
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 1621 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 1738
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 1739 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 1794
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 1795 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 1852
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 1909
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 1910 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 1967
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 1968 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 2027
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 2028 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 2084
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 2085 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 2145 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 2191
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 2192 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 2246
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 2247 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 2304
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 2305 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 2361
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 2362 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 2419
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG----NNK 2976
GKW R + ++++ +N + N+ D+ + D + FGG N
Sbjct: 2420 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Query: 2977 GILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLR 3031
+ P+ + + GC++ I I+ ++ + + +G+ GC ++ VSF ++
Sbjct: 2480 SMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVE 2538
Query: 3032 FVDVTSE-NPQLTLKFKTAKPNGLLFVYVS-------RTQTAIMPDSISLSLVNGKLVV- 3082
V + ++ L F T +G++ + R + ++ L G+L V
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVH 2598
Query: 3083 ------VSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLHIL 3135
++ + N ++D + H + V + VD+ Y T P+ +
Sbjct: 2599 LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK 2658
Query: 3136 DGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG---- 3191
LF+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 2659 K--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKL 2715
Query: 3192 TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 2716 REDEDGAAPAEIVIQPEPVPTPAFPTPTPV 2745
Score = 201 bits (490), Expect = 4e-50
Identities = 127/405 (31%), Positives = 182/405 (44%), Gaps = 58/405 (14%)
Query: 420 PTDG-------LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDK 465
PTDG +C C Y G SCE C + + C+ C+C G CD
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAES-CDD 768
Query: 466 LTGDC-TCKSKYSGRTCNQCQAGYYNYPT------CKPCNCD----TSGTEPSICDDVSG 514
+TG+C CK G C++C G+Y PT C+PC C ++ P+ D S
Sbjct: 769 VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSL 828
Query: 515 QCICKA---GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST--SC-SADGKCN- 567
IC G+ GPRC++C GY+ Q C PC C+ S SC S G C
Sbjct: 829 GLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI 888
Query: 568 CLTNFGGAQCDQCSPGYY----KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKC 622
C G C+ C+ GY+ +C C C+ GS C G C C++N G +C
Sbjct: 889 CKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 623 DTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
D C+ + + C CNC+ G + SF C +G+ C C+ V G+ C+ C Y
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFG-SKSF-DCEE--SGQ-CWCQPGVTGKKCDRCAHGY 1003
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
+N QE GC C C+ G C+ K+G+C+C + +C +C +
Sbjct: 1004 FNFQEG---GCTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
GC C+C GS+D C+ TGQC+CH + G +C + R H+
Sbjct: 1056 --GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 173 bits (420), Expect = 1e-41
Identities = 105/346 (30%), Positives = 147/346 (42%), Gaps = 49/346 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN + D P +L+ C+ T G C C G+ D +C+P
Sbjct: 865 CQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ + E+ + G+C C+ N +G C+KC+ +
Sbjct: 918 CRCNAGGSFS----EVCHSQT-----------GQC-ECRANVQGQRCDKCKAGTFGLQSA 961
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
R C PC C+ S EESG+C C+P C CA+GYF++ C C C
Sbjct: 962 RG-----CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCECNTVGSVSYVCD 464
+ G +C P G C C N G+ C C + CK C C+TVGS+ + C+
Sbjct: 1017 S---HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICD---------DVSGQ 515
TG C C K+SG C +C G++NYP C C+C GT+ + CD D +GQ
Sbjct: 1074 VNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
C CK G CD+C G + C C C T+T CS
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCS 1176
Score = 147 bits (355), Expect = 1e-33
Identities = 77/224 (34%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCD--FMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY 1378
C E F S +PC C+ S C++ G C CKP GR C C GY+
Sbjct: 847 CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF 906
Query: 1379 G----FPNCRPCHCPS----TAIC-DDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
G NC+PC C + + +C G C C NV+G+ CD+CK TF RGC
Sbjct: 907 GDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 1430 CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTY 1487
CNCN G CE +SG+C C+ V G+ CD C G++ F + C C C+ G
Sbjct: 967 CNCNSFG--SKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNN- 1022
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T +C C N G+ C C + GC C C
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNC 1062
Score = 140 bits (338), Expect = 1e-31
Identities = 78/239 (32%), Positives = 108/239 (45%), Gaps = 22/239 (9%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
LC + F + + +PC C+ GS C++ GQC C+ NV G+ C C+ G +G
Sbjct: 900 LCADGYFGDAVDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 1381 PN---CRPCHCPS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCN 1433
+ C PC+C S + C+++G C C V G+ CDRC FNF + GC C C+
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQ-EGGCTACECS 1017
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP---GHYAFPDCYQCTCNRHGTTYDVC 1490
LG C+ +G+C C N G C C P GH C C C+ G+ C
Sbjct: 1018 HLG-----NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYF-----NLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
+ NT QC C G C C ++ NL D G C +T +CS S T
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQT 1131
Score = 118 bits (284), Expect = 4e-25
Identities = 78/236 (33%), Positives = 101/236 (42%), Gaps = 34/236 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYGFP------NCRPCHCP-- 1389
PC C G E C+ G+C CK + G C C G+YG P +C+PC CP
Sbjct: 756 PCQC--FGHAE-SCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLN 812
Query: 1390 -----STAICD-DNGMCI----CPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGV 1437
+ C D + + CP G C+RC F G C C CN
Sbjct: 813 IPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 1438 VGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQ 1492
C++ SG C C+ GR C+ C G++ +C C CN G+ +VC
Sbjct: 873 FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC--FG-KTTRCSSSYYTW 1545
T QC C+ NV+GQ CD CK F LQ + GC C C FG K+ C S W
Sbjct: 933 QTGQCECRANVQGQRCDKCKAGTFGLQ--SARGCVPCNCNSFGSKSFDCEESGQCW 986
Score = 114 bits (275), Expect = 5e-24
Identities = 71/217 (32%), Positives = 96/217 (44%), Gaps = 49/217 (22%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
C C+ G +C+QC G++ P C+ CNC E ++V+
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C G C+ C G++ R C PC+CDP GS + C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 561 SAD----------GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-- 608
D G C+C T FGG CD+C+ GY YPDC +CNC SG +GS +D
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC--SG-LGSKNEDPCF 483
Query: 609 GLCHCKSNFDGAKCDTCREQFY-----NYPACEECNC 640
G C CK N +G C C+ F+ N+ C+EC C
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 112 bits (269), Expect = 3e-23
Identities = 87/275 (31%), Positives = 113/275 (41%), Gaps = 40/275 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF-CVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+C+C +G C++C G + L S CVPC CN + C+ +G C C G
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW-CQPGVTG 993
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY G C C C + NN CD + G C C P G
Sbjct: 994 KKCDRCAHGYFNFQEGG----CTACECS--HLGNN----CD-PKTGR---CICPPNTIGE 1039
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
+C CA +G + TG CK CNCS + D C+ G C C +GA C
Sbjct: 1040 KCSKCAPNTWG----HSITTG--CKACNCS-TVGSLD-FQCNVNTGQC-NCHPKFSGAKC 1090
Query: 1911 NLCAPGFYGDA------IFSKNCTACICD-EFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C+ G + F A CD E C TG C C+ V G CDRC P
Sbjct: 1091 TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRP 1150
Query: 1964 DHWGLN--TGLGCTPCNCGIASESTQCDDDNGQCR 1996
+GL+ LGC+ C C +TQC + G R
Sbjct: 1151 GKFGLDAKNPLGCSSCYC--FGTTTQCSEAKGLIR 1183
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 2751 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 2805
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 2806 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 2861
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 2862 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 2919
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 2920 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 2974
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 2975 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 3034
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 3035 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 3091
Score = 108 bits (259), Expect = 4e-22
Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC----------DPTGSTSTS 559
+C C+ G CDQC G++ + + +C CNC + + S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 560 CSADGK------C-NCLTNFGGAQCDQCSPGYYK-------YP-DCLSCNCDVSGSIGST 604
+ GK C NC N G C+ C+ G+++ YP C C+CD GS+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 605 C--DDN--------GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C D+ G CHCK+ F G CD C + YP C+ CNC G
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLG------SKNE 479
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
P C CK+ V+G C+ CK ++NLQE N GC++C C+
Sbjct: 480 DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 1434
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 1492
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 1553 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 1609
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 1610 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 1669
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 1670 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 1728
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 1729 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 1788
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 1789 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 1847
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 1848 EINSIIDYVEDIQTKLPPMSEELNDK 1873
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 1379 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 1435
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 1556 KCDGCK 1561
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 1436
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 622 CDTCR 626
CD C+
Sbjct: 1557 CDGCK 1561
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 1434
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 1435 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 1486
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 1547 TCRPGATGRKCDGC--KHWHAREGWECVFC 1574
Score = 94.7 bits (225), Expect = 6e-18
Identities = 70/239 (29%), Positives = 100/239 (41%), Gaps = 56/239 (23%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC----------------DVS 598
+C C N G CDQC PG+++ P +C +CNC ++S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 599 GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYPA-CEECNCDPRGVT--- 646
+I G+C +C N G C+TC + F+ NYP C+ C+CDP G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 647 ----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
A G P C CK G C+ C Y + C+ CNC+ G+ N
Sbjct: 426 CVKDEKHARRGLAPGS--CHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGSKN 478
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
C G C+CK++V C +C GF+ LQ ++ GC EC C + N C +
Sbjct: 479 E-DPC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRCQSS 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 1556 KCDGCKHWHARE--GWE--CVFCGDECTG 1580
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 1367 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 1424
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 1425 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 1484
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 1540
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 1582
Score = 85.0 bits (201), Expect = 5e-15
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 1322 CREAMF---SITSEYNSGARPCLCDFMGSTELEC---------NTFGGQCPCKPNVIGRT 1369
C + F ++ Y +PC CD +GS C G C CK G +
Sbjct: 393 CTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVS 452
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAICDDN---GMCICPKNVEGENCDRCKPYTFNF--DVQ 1424
C C GY G+P+C+ C+C +++ G CIC +NVEG +C RCK FN D
Sbjct: 453 CDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNW 512
Query: 1425 RGCDDCNCN 1433
+GCD+C C+
Sbjct: 513 KGCDECFCS 521
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 1437
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 777 D 777
D
Sbjct: 1558 D 1558
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1510 TCK 1512
CK
Sbjct: 1559 GCK 1561
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 1419 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 1476 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 1535
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 1536 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 1564
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 1420 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 1467
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 1515
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 1516 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 1562
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 1552
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 1553 TGRKCDGCKHWHAREGWECVFCGDEC 1578
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 2794 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 2843
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 2844 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 2887
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 2888 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 2942
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 2943 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 2998
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 2999 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 3058
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 3059 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 3093
Score = 58.8 bits (136), Expect = 3e-07
Identities = 53/200 (26%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTA-----------SF 649
C C+ N G CD C F+ P CE CNC + S
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLG 705
G G +C C G C C ++ + +P C+ C+C+ G+LN +
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 706 ACNTKS-------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
+ K G C CK G CD+C G+ C C+C GS N
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSGLGS--KNE 479
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D G C C VEG C +
Sbjct: 480 DPCFGPCICKENVEGGDCSR 499
Score = 51.2 bits (117), Expect = 7e-05
Identities = 43/154 (27%), Positives = 59/154 (38%), Gaps = 31/154 (20%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEY-NPFGCEQCNC-----------NLAGTLNSL 704
C+C+ G C+ C P + W + CE CNC N+A SL
Sbjct: 307 CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSL 366
Query: 705 GACNTK--SGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNC 758
G C+ C Q+ C+ C DGF+R + N C C CD GS++ C
Sbjct: 367 NIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVC 426
Query: 759 DK---------TTGQCHCHSRVEGRRCDQPIRAH 783
K G CHC + G CD+ R +
Sbjct: 427 VKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 2794 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 2851
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 2852 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 2910
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 2911 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 2967
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 2968 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 3022
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 3023 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 3081
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 3082 IPFRGCI 3088
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 1497
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Query: 1412 DRCK 1415
D CK
Sbjct: 1558 DGCK 1561
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 2182 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 2238
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 2239 RNGTISVRALDGPKASIVPSTHHSTSPPGY 2268
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 2766 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2823
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 2824 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 2934
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 1435
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
>BC093406-1|AAH93406.1| 581|Homo sapiens LAMA3 protein protein.
Length = 581
Score = 505 bits (1246), Expect = e-141
Identities = 218/438 (49%), Positives = 286/438 (65%), Gaps = 27/438 (6%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CD C++ + K HP A+D WWQSPPLS G +YN VNLT+DLGQ FHVAY+ +K
Sbjct: 102 CDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFA 161
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G T+ PWQYF+ S DC + FG+E+ +T+DD V+C TEYS+I
Sbjct: 162 NSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRI 221
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GE+ +SL+N RP + + S L+E+T+ATN+RLR LRT LLGHL+S A++DPT
Sbjct: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGG+C+CNGHA+ C +P + C CQH+TCG C++CC+G+
Sbjct: 282 VTRRYYYSIKDISIGGQCVCNGHAEVCNINNPE---KLFRCECQHHTCGETCDRCCTGYN 338
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q++WR + CE CNCH H + C YDP+++ ++ SL+ G Y GGG C+NCQHNT
Sbjct: 339 QRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTA 398
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C YYRPYG D D C PC CDP + G CE+ SGRC C+P F +C C
Sbjct: 399 GVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRCHCKPNFHGDNCEKC 457
Query: 394 AYGYFDYPNC---------------------KPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
A GY+++P C K C CNL G E C G C C+
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVE 516
Query: 433 GKSCEICEDGYYS-PECK 449
G C+ C G+YS P C+
Sbjct: 517 GPRCDTCRSGFYSFPICQ 534
Score = 109 bits (261), Expect = 2e-22
Identities = 68/237 (28%), Positives = 99/237 (41%), Gaps = 52/237 (21%)
Query: 451 CECNTVGSVSYVCD-KLTGDCTCKSKYSGRTCNQCQAGYYNY---PT-------CKPCNC 499
C CN V + + + C C+ G TC++C GY P C+ CNC
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 500 DTSGTEPSICDDVS---------------GQCI-CKAGFGGPRCDQCLSGYYMQV---LG 540
+ DV G CI C+ G C+QC GYY +
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 541 RERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL--------- 591
C+PC+CDP + G+C+C NF G C++C+ GYY +P CL
Sbjct: 419 APDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVST 477
Query: 592 ------------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE 636
C+C++ G + CD +G C C+ +G +CDTCR FY++P C+
Sbjct: 478 PSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQ 534
Score = 103 bits (247), Expect = 1e-20
Identities = 76/243 (31%), Positives = 107/243 (44%), Gaps = 70/243 (28%)
Query: 328 CQHNTEGINCNKCRPTY----YRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
CQH+T G C++C Y +RP W++ C+ C C H S NC
Sbjct: 321 CQHHTCGETCDRCCTGYNQRRWRPAA--WEQSHECEACNCHGHAS--NC----------- 365
Query: 384 EFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDG 442
Y+D P+ + +LN T+G + G+C C++N AG +CE C G
Sbjct: 366 -------------YYD-PDVERQQASLN-TQGIYAG--GGVCINCQHNTAGVNCEQCAKG 408
Query: 443 YYSPE---------CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT 493
YY P C C C+ + C++ +G C CK + G C +C GYYN+P
Sbjct: 409 YYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPF 466
Query: 494 C---------------------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
C K C+C+ G P IC D G+C+C+ G GPRCD C S
Sbjct: 467 CLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVEGPRCDTCRS 525
Query: 533 GYY 535
G+Y
Sbjct: 526 GFY 528
Score = 95.5 bits (227), Expect = 3e-18
Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 36/229 (15%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGN 1882
N A C+++ L C CQ G C+ C GY C+ CNC G+
Sbjct: 302 NGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGH 361
Query: 1883 IN-----PQDPGSCDSIN--------GDCLKCVNNTAGAACNLCAPGFY---GDAIFSKN 1926
+ P S+N G C+ C +NTAG C CA G+Y G + + +
Sbjct: 362 ASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPD 421
Query: 1927 -CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLG------CTP--- 1976
C C CD C+ +G C C+P G+ C++CA ++ L TP
Sbjct: 422 GCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 481
Query: 1977 ---------CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
C+C + + D +G+C C GV G +CD C +GF+++
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSF 530
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/233 (30%), Positives = 99/233 (42%), Gaps = 44/233 (18%)
Query: 1765 CQCNGHSDQCDVNTGICL---NCADNTIGDHCEFCMSGYH----GDATVGTPRDCLICAC 1817
C CNGH++ C++N L C +T G+ C+ C +GY+ A +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1818 PMPYPSNNF----------ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTD 1867
+ SN + +L+ G + NCQ G CE CA GYY P
Sbjct: 359 -HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVP 416
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG------DA 1921
+ D C PC+C +P+ C+ +G C C N G C CA G+Y
Sbjct: 417 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIP 471
Query: 1922 IF-----------SKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRC 1961
IF + + C C+ G+ CD+ G C+CRPGV G +CD C
Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGPRCDTC 523
Score = 87.4 bits (207), Expect = 9e-16
Identities = 68/224 (30%), Positives = 94/224 (41%), Gaps = 55/224 (24%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRL---PSGF-----CVPCQCNGHSDQC-----------DV 1776
C+C G +C++C G+ + P+ + C C C+GH+ C +
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 1777 NT-------GICLNCADNTIGDHCEFCMSGYHG--DATVGTPRDCLICACPMPYPSNNFA 1827
NT G+C+NC NT G +CE C GY+ V P C+ C+C +
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH------ 432
Query: 1828 LSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGI-------------PEDTDLHTGDYC 1874
D E GS C+C+P + G CE CA GYY P D GD
Sbjct: 433 --ADGCEQGS-GRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD-I 488
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFY 1918
K C+C N+ P CD+ +G CL C G C+ C GFY
Sbjct: 489 KGCDC--NLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFY 528
Score = 86.2 bits (204), Expect = 2e-15
Identities = 47/147 (31%), Positives = 67/147 (45%), Gaps = 32/147 (21%)
Query: 1398 GMCI-CPKNVEGENCDRC-----KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
G+CI C N G NC++C +PY D GC C+C+P G CE SG+C
Sbjct: 388 GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG----CEQGSGRC 443
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQ---------------------CTCNRHGTTYDVC 1490
C+ N G C+ C G+Y FP C + C CN G ++C
Sbjct: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC 503
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYFN 1517
D + +C C+ V G CDTC+ +++
Sbjct: 504 DAH-GRCLCRPGVEGPRCDTCRSGFYS 529
Score = 80.6 bits (190), Expect = 1e-13
Identities = 63/214 (29%), Positives = 92/214 (42%), Gaps = 49/214 (22%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC---------DPT-----GS 555
+C C+ G CD+C +GY + + +C CNC DP S
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 556 TSTS--CSADGKC-NCLTNFGGAQCDQCSPGYYK-------YPD-CLSCNCDVSGSIGST 604
+T + G C NC N G C+QC+ GYY+ PD C+ C+CD + G
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-- 435
Query: 605 CDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTAS-------FAGC---- 652
C+ +G CHCK NF G C+ C +YN+P C P +S GC
Sbjct: 436 CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNL 495
Query: 653 -GSVP----AGELCQCKDRVQGRICNDCKPLYWN 681
G +P A C C+ V+G C+ C+ +++
Sbjct: 496 EGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYS 529
Score = 79.4 bits (187), Expect = 2e-13
Identities = 50/146 (34%), Positives = 71/146 (48%), Gaps = 27/146 (18%)
Query: 1738 CPRAYRGLSCEQCAEGHYR-------LPSGFCVPCQCNG-HSDQCDVNTGICLNCADNTI 1789
C G++CEQCA+G+YR P G C+PC C+ H+D C+ +G C +C N
Sbjct: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-CIPCSCDPEHADGCEQGSGRC-HCKPNFH 450
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS-----CDLSENGSLIS---- 1840
GD+CE C GY+ P I P+ PS+ ++ CD + G L
Sbjct: 451 GDNCEKCAIGYYN-----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 505
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIP 1863
C C+PG G RC+ C +G+Y P
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP 531
Score = 70.5 bits (165), Expect = 1e-10
Identities = 52/150 (34%), Positives = 64/150 (42%), Gaps = 33/150 (22%)
Query: 1356 GGQC-PCKPNVIGRTCSACRTGYY---GFP-----NCRPCHC-PSTAI-CDD-NGMCICP 1403
GG C C+ N G C C GYY G P C PC C P A C+ +G C C
Sbjct: 387 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCK 446
Query: 1404 KNVEGENCDRCKPYTFNF------------------DVQRGCDDCNCNPLGVVGNQLQCE 1445
N G+NC++C +NF V C+CN GV+ C+
Sbjct: 447 PNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPE--ICD 504
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDC 1475
A G+C CR V G CD C G Y+FP C
Sbjct: 505 A-HGRCLCRPGVEGPRCDTCRSGFYSFPIC 533
Score = 70.1 bits (164), Expect = 1e-10
Identities = 40/145 (27%), Positives = 65/145 (44%), Gaps = 26/145 (17%)
Query: 1945 GTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCGIASESTQCDDDNGQCRCA 1998
G C+ C+ G C++CA ++ ++ GC PC+C + C+ +G+C C
Sbjct: 388 GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCD-PEHADGCEQGSGRCHCK 446
Query: 1999 KGVTGKQCDQCAAGFWNY------------TKDGCD-------HCNCNTGYSVGFMCNAT 2039
G C++CA G++N+ T D C+CN + +C+A
Sbjct: 447 PNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH 506
Query: 2040 GQCECLPGVIGEKCDRCPERWVLIP 2064
G+C C PGV G +CD C + P
Sbjct: 507 GRCLCRPGVEGPRCDTCRSGFYSFP 531
Score = 62.9 bits (146), Expect = 2e-08
Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 32/169 (18%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPY 1417
+C C+ + G TC C TGY RP + C+ C C + NC
Sbjct: 318 RCECQHHTCGETCDRCCTGY-NQRRWRPAAWEQSHECE---ACNC--HGHASNC------ 365
Query: 1418 TFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYA----- 1471
++ DV+R + N G+ A G C C+ N G C+ C G+Y
Sbjct: 366 YYDPDVER--QQASLNTQGIY-------AGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP 416
Query: 1472 --FPD-CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFN 1517
PD C C+C+ D C+Q + +C+CK N G C+ C Y+N
Sbjct: 417 VDAPDGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYN 463
Score = 62.1 bits (144), Expect = 4e-08
Identities = 38/125 (30%), Positives = 51/125 (40%), Gaps = 27/125 (21%)
Query: 1327 FSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCR-- 1384
+ + + G PC CD + C G+C CKPN G C C GYY FP C
Sbjct: 413 YGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRI 470
Query: 1385 ---PCHCPST--------------------AICDDNGMCICPKNVEGENCDRCKPYTFNF 1421
P PS+ ICD +G C+C VEG CD C+ ++F
Sbjct: 471 PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSF 530
Query: 1422 DVQRG 1426
+ +G
Sbjct: 531 PICQG 535
Score = 58.4 bits (135), Expect = 5e-07
Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 46/208 (22%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY---PA-------CEECNC-----------DPRGVTASF 649
C C+ + G CD C + PA CE CNC D AS
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWN---LQEYNPFGCEQCNCNLAGTLNSLG 705
G G +C C+ G C C Y+ + P GC C+C+
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDP----EHAD 434
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRL---------------QTNDVFGCTE-CDCD 749
C SG+C CK + C++C G+Y + V G + CDC+
Sbjct: 435 GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN 494
Query: 750 IGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G + CD G+C C VEG RCD
Sbjct: 495 LEGVLPEICD-AHGRCLCRPGVEGPRCD 521
Score = 56.4 bits (130), Expect = 2e-06
Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 29/151 (19%)
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFG------CEQCNCN--------------LAGT 700
C+C+ G C+ C Y N + + P CE CNC+ +
Sbjct: 319 CECQHHTCGETCDRCCTGY-NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 701 LNSLGACNTKSGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDN 756
LN+ G G C+ C+ + C+QC G+YR + + GC C CD + +
Sbjct: 378 LNTQGIY-AGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHA--D 434
Query: 757 NCDKTTGQCHCHSRVEGRRCDQPIRAHY-FP 786
C++ +G+CHC G C++ +Y FP
Sbjct: 435 GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFP 465
>BC085017-1|AAH85017.1| 561|Homo sapiens LAMA5 protein protein.
Length = 561
Score = 497 bits (1226), Expect = e-139
Identities = 206/380 (54%), Positives = 270/380 (71%), Gaps = 1/380 (0%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CDIC A N K HP A+D WWQSPPLSRG++YNEVN+T+DLGQ FHVAYV +K
Sbjct: 103 CDICTAANSNKAHPASNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFA 162
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G+T++PWQ+F+ S +DC FG ++L+ IT+DD+ IC+TEYS+I
Sbjct: 163 NSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRI 222
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GEI +SL+N RP + + S +L+E+T+ATNVRLR LRT LLGHLM A +DPT
Sbjct: 223 VPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT 282
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGGRC+C+GHAD C+ DP L C CQHNTCG C++CC GF
Sbjct: 283 VTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFR-LQCTCQHNTCGGTCDRCCPGFN 341
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q+ W+ + C+ CNC+ H T+C YDPE+D +R S ++G Y+GGG C++CQH+T
Sbjct: 342 QQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTA 401
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C P +YR D VC+ C C+ F+ G CE+ +GRC CRP F C C
Sbjct: 402 GVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVC 461
Query: 394 AYGYFDYPNCKPCTCNLNGT 413
A G+ +P+C P + N T
Sbjct: 462 AEGFTGFPSCYPTPSSSNDT 481
Score = 81.8 bits (193), Expect = 4e-14
Identities = 55/207 (26%), Positives = 85/207 (41%), Gaps = 24/207 (11%)
Query: 1765 CQCNGHSDQCDVNTG-----ICLNCADNTIGDHCEFCMSGYHGD----ATVGTPRDCLIC 1815
C C+GH+D CD + C NT G C+ C G++ AT + +C C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
Query: 1816 AC---------PMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDT 1866
C + S D + G + +CQ G CE C G+Y P +
Sbjct: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSP-NH 418
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSK 1925
L + C+ CNC + G+C+ + G C C N +G C++CA GF G + +
Sbjct: 419 PLDSPHVCRRCNCESDFT---DGTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPT 474
Query: 1926 NCTACICDEFGMADCDSTTGTCVCRPG 1952
++ E + +G +CRPG
Sbjct: 475 PSSSNDTREQVLPAGQIVSGVSLCRPG 501
Score = 80.6 bits (190), Expect = 1e-13
Identities = 51/180 (28%), Positives = 74/180 (41%), Gaps = 33/180 (18%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC---------DP-------T 553
QC C+ G CD+C G+ Q +C CNC DP +
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 554 GSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGST 604
S + G C +C + G C++C PG+Y+ P+ C CNC+ S T
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE-SDFTDGT 439
Query: 605 CDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG-ELCQ 662
C+D G C+C+ NF G +CD C E F +P+C G + +G LC+
Sbjct: 440 CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVSGVSLCR 499
Score = 74.1 bits (174), Expect = 9e-12
Identities = 68/246 (27%), Positives = 102/246 (41%), Gaps = 57/246 (23%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C CH H C D RL +C CQHNT G C++C P + +
Sbjct: 300 CVCHGHADACDAKDPTDPFRL------------QC-TCQHNTCGGTCDRCCPGFNQ---- 342
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP-NCKPCTCN 409
QP + P +T N E C C DC Y+D + + + +
Sbjct: 343 --------QPWK--P--ATANSANECQSCNCYGH--ATDC------YYDPEVDRRRASQS 382
Query: 410 LNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYY--------SPE-CKNCECNTVGSV 459
L+GT G+C C+++ AG +CE C G+Y SP C+ C C +
Sbjct: 383 LDGTY-----QGGGVCIDCQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCES-DFT 436
Query: 460 SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC---DDVSGQC 516
C+ LTG C C+ +SG C+ C G+ +P+C P ++ T + VSG
Sbjct: 437 DGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVSGVS 496
Query: 517 ICKAGF 522
+C+ G+
Sbjct: 497 LCRPGW 502
Score = 70.9 bits (166), Expect = 8e-11
Identities = 54/205 (26%), Positives = 84/205 (40%), Gaps = 32/205 (15%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG----RCECRPEFQPPDCSSCAYGY 397
PT R Y ++ + C C H + ++ + +C C+ C C G+
Sbjct: 281 PTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGF 340
Query: 398 FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVG 457
P KP T N C C C Y +A D YY PE +
Sbjct: 341 NQQP-WKPATAN----SANECQS----CNC-YGHA-------TDCYYDPEVDRRRASQSL 383
Query: 458 SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY---NYP-----TCKPCNCDTSGTEPSIC 509
+Y + DC + +G C +C G+Y N+P C+ CNC++ T+ + C
Sbjct: 384 DGTYQGGGVCIDC--QHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT-C 440
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGY 534
+D++G+C C+ F G RCD C G+
Sbjct: 441 EDLTGRCYCRPNFSGERCDVCAEGF 465
Score = 69.3 bits (162), Expect = 2e-10
Identities = 43/150 (28%), Positives = 61/150 (40%), Gaps = 29/150 (19%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
CTC+ G TC++C G+ P C+ CNC T+ +V
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C+ G C++CL G+Y L C CNC+ + T
Sbjct: 382 SLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCE 441
Query: 561 SADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
G+C C NF G +CD C+ G+ +P C
Sbjct: 442 DLTGRCYCRPNFSGERCDVCAEGFTGFPSC 471
Score = 64.5 bits (150), Expect = 7e-09
Identities = 53/172 (30%), Positives = 70/172 (40%), Gaps = 39/172 (22%)
Query: 1930 CICDEFGMAD-CDSTTGT------CVCRPGVIGEKCDRCAPDH----WG---LNTGLGCT 1975
C+C G AD CD+ T C C+ G CDRC P W N+ C
Sbjct: 300 CVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357
Query: 1976 PCNC-GIASE------------STQCD---DDNGQC-RCAKGVTGKQCDQCAAGFW---N 2015
CNC G A++ S D G C C G C++C GF+ N
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSPN 417
Query: 2016 YTKDG---CDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP 2064
+ D C CNC + ++ G + TG+C C P GE+CD C E + P
Sbjct: 418 HPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469
Score = 62.9 bits (146), Expect = 2e-08
Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 35/172 (20%)
Query: 1877 CNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFY------GDAIFSKNCTA 1929
C C G+ + D D C C +NT G C+ C PGF A + C +
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 1930 CICDEFGMA-DC---------------DSTT---GTCV-CRPGVIGEKCDRCAPDHWG-- 1967
C C +G A DC D T G C+ C+ G C+RC P +
Sbjct: 359 CNC--YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSP 416
Query: 1968 ---LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
L++ C CNC C+D G+C C +G++CD CA GF +
Sbjct: 417 NHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGF 468
Score = 62.9 bits (146), Expect = 2e-08
Identities = 49/168 (29%), Positives = 61/168 (36%), Gaps = 39/168 (23%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-C------------ 1394
QC C+ N G TC C G+ P C+ C+C A C
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 1395 -------DDNGMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQ 1441
G+CI C + G NC+RC P + D C CNC G
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT- 439
Query: 1442 LQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDV 1489
CE +G+C CR N G CD C G FP CY + + T V
Sbjct: 440 --CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQV 485
Score = 62.5 bits (145), Expect = 3e-08
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 25/140 (17%)
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFG------CEQCNCNLAGT-------------L 701
C C+ G C+ C P + N Q + P C+ CNC T
Sbjct: 322 CTCQHNTCGGTCDRCCPGF-NQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 702 NSLGACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG---CTECDCDIGGSIDNN 757
SL G C+ C+ H C++CL GFYR + + C C+C+ D
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE-SDFTDGT 439
Query: 758 CDKTTGQCHCHSRVEGRRCD 777
C+ TG+C+C G RCD
Sbjct: 440 CEDLTGRCYCRPNFSGERCD 459
Score = 57.2 bits (132), Expect = 1e-06
Identities = 42/147 (28%), Positives = 57/147 (38%), Gaps = 34/147 (23%)
Query: 1400 CICPKNVEGENCDRC---------KPYTFNFDVQRGCDDCNCNPLGV-------VGNQLQ 1443
C C N G CDRC KP T N + C CNC V +
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANE--CQSCNCYGHATDCYYDPEVDRRRA 379
Query: 1444 CEA------DSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYD 1488
++ G C C+ + G C+ C+PG Y P+ C +C C T
Sbjct: 380 SQSLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTD-G 438
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C+ T +CYC+ N G+ CD C E +
Sbjct: 439 TCEDLTGRCYCRPNFSGERCDVCAEGF 465
Score = 56.8 bits (131), Expect = 1e-06
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 28/147 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNC---------DPR--GVTASF 649
C C+ N G CD C F P C+ CNC DP AS
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEY---NPFGCEQCNCNLAGTLNSLG 705
+ G+ G +C C+ G C C P ++ + +P C +CNC T G
Sbjct: 382 SLDGTYQGGGVCIDCQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTD---G 438
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGF 732
C +G+C C+ + +CD C +GF
Sbjct: 439 TCEDLTGRCYCRPNFSGERCDVCAEGF 465
Score = 48.4 bits (110), Expect = 5e-04
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
R C C+ T+ C G+C C+PN G C C G+ GFP+C P PS++ +D
Sbjct: 427 RRCNCE-SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYP--TPSSS--NDT 481
Query: 1398 GMCICPKNVEGENCDRCKP 1416
+ P C+P
Sbjct: 482 REQVLPAGQIVSGVSLCRP 500
Score = 42.7 bits (96), Expect = 0.024
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCNGH--SDQCDVNTGICLNCADNTI 1789
C G++CE+C G YR P+ C C C C+ TG C C N
Sbjct: 396 CQHHTAGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY-CRPNFS 454
Query: 1790 GDHCEFCMSGYHG 1802
G+ C+ C G+ G
Sbjct: 455 GERCDVCAEGFTG 467
Score = 38.3 bits (85), Expect = 0.52
Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 10/71 (14%)
Query: 1477 QCTCNRHGTTYDVCDQNTA---QCYCKTNVRGQACDTCKEEYFNLQDDNP------DGCT 1527
+C C+ H D D QC C+ N G CD C FN Q P + C
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPG-FNQQPWKPATANSANECQ 357
Query: 1528 KCFCFGKTTRC 1538
C C+G T C
Sbjct: 358 SCNCYGHATDC 368
>AL354836-6|CAI12295.1| 500|Homo sapiens laminin, alpha 5 protein.
Length = 500
Score = 497 bits (1226), Expect = e-139
Identities = 206/380 (54%), Positives = 270/380 (71%), Gaps = 1/380 (0%)
Query: 34 CDICDANNEAKKHPPEYAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMG 93
CDIC A N K HP A+D WWQSPPLSRG++YNEVN+T+DLGQ FHVAYV +K
Sbjct: 103 CDICTAANSNKAHPASNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFA 162
Query: 94 NSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKI 153
NSPRP+LWVLE+S D+G+T++PWQ+F+ S +DC FG ++L+ IT+DD+ IC+TEYS+I
Sbjct: 163 NSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRI 222
Query: 154 VPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPT 213
VPLE+GEI +SL+N RP + + S +L+E+T+ATNVRLR LRT LLGHLM A +DPT
Sbjct: 223 VPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT 282
Query: 214 VTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFE 273
VTRRY+YSIKDISIGGRC+C+GHAD C+ DP L C CQHNTCG C++CC GF
Sbjct: 283 VTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFR-LQCTCQHNTCGGTCDRCCPGFN 341
Query: 274 QKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTE 333
Q+ W+ + C+ CNC+ H T+C YDPE+D +R S ++G Y+GGG C++CQH+T
Sbjct: 342 QQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTT 401
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC 393
G+NC +C P +YR D VC+ C C+ F+ G CE+ +GRC CRP F C C
Sbjct: 402 GVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVC 461
Query: 394 AYGYFDYPNCKPCTCNLNGT 413
A G+ +P+C P + N T
Sbjct: 462 AEGFTGFPSCYPTPSSSNDT 481
Score = 79.0 bits (186), Expect = 3e-13
Identities = 47/152 (30%), Positives = 67/152 (44%), Gaps = 32/152 (21%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC---------DP-------T 553
QC C+ G CD+C G+ Q +C CNC DP +
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 554 GSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGST 604
S + G C +C + G C++C PG+Y+ P+ C CNC+ S T
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE-SDFTDGT 439
Query: 605 CDD-NGLCHCKSNFDGAKCDTCREQFYNYPAC 635
C+D G C+C+ NF G +CD C E F +P+C
Sbjct: 440 CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSC 471
Score = 78.6 bits (185), Expect = 4e-13
Identities = 49/173 (28%), Positives = 72/173 (41%), Gaps = 23/173 (13%)
Query: 1765 CQCNGHSDQCDVNTG-----ICLNCADNTIGDHCEFCMSGYHGD----ATVGTPRDCLIC 1815
C C+GH+D CD + C NT G C+ C G++ AT + +C C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
Query: 1816 AC---------PMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDT 1866
C + S D + G + +CQ G CE C G+Y P +
Sbjct: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSP-NH 418
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG 1919
L + C+ CNC + G+C+ + G C C N +G C++CA GF G
Sbjct: 419 PLDSPHVCRRCNCESDFT---DGTCEDLTGRCY-CRPNFSGERCDVCAEGFTG 467
Score = 70.9 bits (166), Expect = 8e-11
Identities = 54/205 (26%), Positives = 84/205 (40%), Gaps = 32/205 (15%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG----RCECRPEFQPPDCSSCAYGY 397
PT R Y ++ + C C H + ++ + +C C+ C C G+
Sbjct: 281 PTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGF 340
Query: 398 FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVG 457
P KP T N C C C Y +A D YY PE +
Sbjct: 341 NQQP-WKPATAN----SANECQS----CNC-YGHA-------TDCYYDPEVDRRRASQSL 383
Query: 458 SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY---NYP-----TCKPCNCDTSGTEPSIC 509
+Y + DC + +G C +C G+Y N+P C+ CNC++ T+ + C
Sbjct: 384 DGTYQGGGVCIDC--QHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT-C 440
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGY 534
+D++G+C C+ F G RCD C G+
Sbjct: 441 EDLTGRCYCRPNFSGERCDVCAEGF 465
Score = 68.5 bits (160), Expect = 4e-10
Identities = 43/150 (28%), Positives = 61/150 (40%), Gaps = 29/150 (19%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDVS------ 513
CTC+ G TC++C G+ P C+ CNC T+ +V
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
Query: 514 ---------GQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSC 560
G CI C+ G C++CL G+Y L C CNC+ + T
Sbjct: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCE 441
Query: 561 SADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
G+C C NF G +CD C+ G+ +P C
Sbjct: 442 DLTGRCYCRPNFSGERCDVCAEGFTGFPSC 471
Score = 68.1 bits (159), Expect = 6e-10
Identities = 62/229 (27%), Positives = 93/229 (40%), Gaps = 54/229 (23%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C CH H C D RL +C CQHNT G C++C P + +
Sbjct: 300 CVCHGHADACDAKDPTDPFRL------------QC-TCQHNTCGGTCDRCCPGFNQ---- 342
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP-NCKPCTCN 409
QP + P +T N E C C DC Y+D + + + +
Sbjct: 343 --------QPWK--P--ATANSANECQSCNCYGH--ATDC------YYDPEVDRRRASQS 382
Query: 410 LNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYY--------SPE-CKNCECNTVGSV 459
L+GT G+C C+++ G +CE C G+Y SP C+ C C +
Sbjct: 383 LDGTY-----QGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCES-DFT 436
Query: 460 SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSI 508
C+ LTG C C+ +SG C+ C G+ +P+C P ++ T +
Sbjct: 437 DGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQV 485
Score = 66.5 bits (155), Expect = 2e-09
Identities = 54/172 (31%), Positives = 71/172 (41%), Gaps = 39/172 (22%)
Query: 1930 CICDEFGMAD-CDSTTGT------CVCRPGVIGEKCDRCAPDH----WG---LNTGLGCT 1975
C+C G AD CD+ T C C+ G CDRC P W N+ C
Sbjct: 300 CVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357
Query: 1976 PCNC-GIASE------------STQCD---DDNGQC-RCAKGVTGKQCDQCAAGFW---N 2015
CNC G A++ S D G C C TG C++C GF+ N
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
Query: 2016 YTKDG---CDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP 2064
+ D C CNC + ++ G + TG+C C P GE+CD C E + P
Sbjct: 418 HPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469
Score = 62.9 bits (146), Expect = 2e-08
Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 35/172 (20%)
Query: 1877 CNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFY------GDAIFSKNCTA 1929
C C G+ + D D C C +NT G C+ C PGF A + C +
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 1930 CICDEFGMA-DC---------------DST---TGTCV-CRPGVIGEKCDRCAPDHW--- 1966
C C +G A DC D T G C+ C+ G C+RC P +
Sbjct: 359 CNC--YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSP 416
Query: 1967 --GLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
L++ C CNC C+D G+C C +G++CD CA GF +
Sbjct: 417 NHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGF 468
Score = 62.9 bits (146), Expect = 2e-08
Identities = 49/168 (29%), Positives = 61/168 (36%), Gaps = 39/168 (23%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-C------------ 1394
QC C+ N G TC C G+ P C+ C+C A C
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 1395 -------DDNGMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQ 1441
G+CI C + G NC+RC P + D C CNC G
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT- 439
Query: 1442 LQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDV 1489
CE +G+C CR N G CD C G FP CY + + T V
Sbjct: 440 --CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQV 485
Score = 61.7 bits (143), Expect = 5e-08
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 25/140 (17%)
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFG------CEQCNCNLAGT-------------L 701
C C+ G C+ C P + N Q + P C+ CNC T
Sbjct: 322 CTCQHNTCGGTCDRCCPGF-NQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 702 NSLGACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG---CTECDCDIGGSIDNN 757
SL G C+ C+ H C++CL GFYR + + C C+C+ D
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE-SDFTDGT 439
Query: 758 CDKTTGQCHCHSRVEGRRCD 777
C+ TG+C+C G RCD
Sbjct: 440 CEDLTGRCYCRPNFSGERCD 459
Score = 60.9 bits (141), Expect = 8e-08
Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 36/157 (22%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC----DVNT---- 1778
+C C G +C++C G + P + C C C GH+ C +V+
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 1779 ----------GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNF 1826
G+C++C +T G +CE C+ G++ + +P C C C +
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTC 440
Query: 1827 ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP 1863
DL+ C C+P + G RC+ CA G+ G P
Sbjct: 441 E---DLTGR-----CYCRPNFSGERCDVCAEGFTGFP 469
Score = 57.2 bits (132), Expect = 1e-06
Identities = 42/147 (28%), Positives = 57/147 (38%), Gaps = 34/147 (23%)
Query: 1400 CICPKNVEGENCDRC---------KPYTFNFDVQRGCDDCNCNPLGV-------VGNQLQ 1443
C C N G CDRC KP T N + C CNC V +
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANE--CQSCNCYGHATDCYYDPEVDRRRA 379
Query: 1444 CEA------DSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYD 1488
++ G C C+ + G C+ C+PG Y P+ C +C C T
Sbjct: 380 SQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTD-G 438
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C+ T +CYC+ N G+ CD C E +
Sbjct: 439 TCEDLTGRCYCRPNFSGERCDVCAEGF 465
Score = 56.8 bits (131), Expect = 1e-06
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 28/147 (19%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNC---------DPR--GVTASF 649
C C+ N G CD C F P C+ CNC DP AS
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWNLQEY---NPFGCEQCNCNLAGTLNSLG 705
+ G+ G +C C+ G C C P ++ + +P C +CNC T G
Sbjct: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTD---G 438
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGF 732
C +G+C C+ + +CD C +GF
Sbjct: 439 TCEDLTGRCYCRPNFSGERCDVCAEGF 465
Score = 48.8 bits (111), Expect = 4e-04
Identities = 27/72 (37%), Positives = 32/72 (44%), Gaps = 13/72 (18%)
Query: 1356 GGQC-PCKPNVIGRTCSACRTGYYGFPN--------CRPCHCPST---AICDD-NGMCIC 1402
GG C C+ + G C C G+Y PN CR C+C S C+D G C C
Sbjct: 390 GGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYC 449
Query: 1403 PKNVEGENCDRC 1414
N GE CD C
Sbjct: 450 RPNFSGERCDVC 461
Score = 48.0 bits (109), Expect = 6e-04
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP 1385
R C C+ T+ C G+C C+PN G C C G+ GFP+C P
Sbjct: 427 RRCNCE-SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYP 473
Score = 38.3 bits (85), Expect = 0.52
Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 10/71 (14%)
Query: 1477 QCTCNRHGTTYDVCDQNTA---QCYCKTNVRGQACDTCKEEYFNLQDDNP------DGCT 1527
+C C+ H D D QC C+ N G CD C FN Q P + C
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPG-FNQQPWKPATANSANECQ 357
Query: 1528 KCFCFGKTTRC 1538
C C+G T C
Sbjct: 358 SCNCYGHATDC 368
>M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.
Length = 1609
Score = 442 bits (1090), Expect = e-123
Identities = 290/949 (30%), Positives = 439/949 (46%), Gaps = 85/949 (8%)
Query: 1317 NETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQ-CPCKPNVIGRTCSACRT 1375
N+ + + ++I S++ G R C C+ S E N F C CK N G C C
Sbjct: 265 NDPKVLKSYYYAI-SDFAVGGR-CKCNGHAS-ECMKNEFDKLVCNCKHNTYGVDCEKCLP 321
Query: 1376 GYYGFP----------NCRPCHCPSTAI-C----------DDNGMCI-CPKNVEGENCDR 1413
+ P C PC C + C G C C N +G +C+R
Sbjct: 322 FFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCER 381
Query: 1414 CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP 1473
C+ F C C+C+P+G + Q C++ G+C+C+ V G CD C PG ++
Sbjct: 382 CRENFFRLGNNEACSSCHCSPVGSLSTQ--CDS-YGRCSCKPGVMGDKCDRCQPGFHSLT 438
Query: 1474 D--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ C C+C+ G+ D C+ T +C CK NV G C+ CK +FNL+ NP GCT CFC
Sbjct: 439 EAGCRPCSCDPSGSI-DECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Query: 1532 FGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVT 1591
FG ++ C+++ ++ + + +D + E E ++ ++D
Sbjct: 498 FGHSSVCTNA--VGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYF 555
Query: 1592 NGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVE 1651
YF AP +LGK++ SYG L+++ R ++A D+++ G G V +
Sbjct: 556 P---RYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDT--RLSAEDLVLEGA-GLRVSVPLI 609
Query: 1652 QPPVGMPWTHSVK--LSEEEFSTLDGAP-VTRDQFMHALVNISGLYIRASYWEYSIETSL 1708
P +VK E + P +T +F L N++ + IR +Y E S L
Sbjct: 610 AQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGY-L 668
Query: 1709 SNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRL-----PSGFCV 1763
+V L G + AT VE C CP Y G CE C G+ R P CV
Sbjct: 669 DDVTL---ASARPGPGVP---ATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCV 722
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
C CNGHS+ CD TG+C NC DNT G HCE C GY+GD+T GT DC C CP
Sbjct: 723 LCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPG---- 777
Query: 1824 NNFALSCDLSENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN 1882
SC + + C NC G G RCE C GY+G P + C+ C CS N
Sbjct: 778 ---GSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVR-LCRLCQCSDN 833
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIF---SKNCTACICDEFG--- 1936
I+P G+C+ + G+CLKC+ NTAG C+ C GF+G+ + + C AC C+ +G
Sbjct: 834 IDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNPYGTMK 893
Query: 1937 -MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQ 1994
+ C+ TG C C P V G+ C C P + L +G GC C+C + S + QCD GQ
Sbjct: 894 QQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQ 953
Query: 1995 CRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C C G+TG+ C++C + + +GC C+C+ S+ C G+CEC G +G +CD
Sbjct: 954 CECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCD 1013
Query: 2055 RCPERWVLIPQ-EGCLECDSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYIS 2113
+C E + GC EC +C + V D L + + + T + ++
Sbjct: 1014 QCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKL----QELESLIANLGTGDEM--VT 1067
Query: 2114 NQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDA 2173
+Q R K A+ + +D+ +K ++ +NL+ + QISR +
Sbjct: 1068 DQAFEDRLKEAEREVMDLLREAQDVKDVD---QNLMDRLQRVNNTLSSQISRLQNIRNTI 1124
Query: 2174 ERTLAAVRESAREATEVVKHVADLAT-GLELSQQPKVDSALTEARQIRD 2221
E T + E AR E + + ++A+ LE ++ + ++T+ D
Sbjct: 1125 EET-GNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGD 1172
Score = 274 bits (673), Expect = 3e-72
Identities = 145/427 (33%), Positives = 210/427 (49%), Gaps = 31/427 (7%)
Query: 31 TSVCDICDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKY-NEVNLTIDLGQEFHV 85
T C +CDA +H + D TWWQS + G++Y + +NLT+ LG+ F +
Sbjct: 86 TKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDI 145
Query: 86 AYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVI 145
YV +K S RPE + + K T + P+QY+S S ++ + ++ + +
Sbjct: 146 TYVRLKFHTS-RPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQAL 204
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C+ E+S PL G + S L RPS+ + NS VLQEW AT++R+ T N L
Sbjct: 205 CTDEFSDFSPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRV----TLNRLNTFG 260
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
DP V + Y+Y+I D ++GGRC CNGHA C + LVC C+HNT G C
Sbjct: 261 DEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASEC----MKNEFDKLVCNCKHNTYGVDC 316
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
KC F + WR + C PC+C+ + EC +DPE+ G GG C
Sbjct: 317 EKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS------TGH---GGHC 367
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
NCQ NT+G +C +CR ++R G + C C C P S + GRC C+P
Sbjct: 368 TNCQDNTDGAHCERCRENFFR-LGNN----EACSSCHCSPVGSLSTQCDSYGRCSCKPGV 422
Query: 386 QPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PC+C+ +G+ E C G C CK N G +CE C+ G+
Sbjct: 423 MGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNVETGRCVCKDNVEGFNCERCKPGF 481
Query: 444 YSPECKN 450
++ E N
Sbjct: 482 FNLESSN 488
Score = 185 bits (451), Expect = 2e-45
Identities = 108/345 (31%), Positives = 156/345 (45%), Gaps = 39/345 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C G C C Y R C C C+ H T C+ E+G C CR
Sbjct: 692 CPVGYGGQFCEMCLSGYRRET-PNLGPYSPCVLCACNGHSET--CDPETGVCNCRDNTAG 748
Query: 388 PDCSSCAYGYFD------YPNCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICE 440
P C C+ GY+ +C+PC C + + +C C GK CE+C+
Sbjct: 749 PHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 441 DGYYSPE---------CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQAGY 488
DGY+ C+ C+C+ + V C++LTG+C C +G C++C+ G+
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 489 YNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
+ P CK CNC+ GT + S C+ V+GQC C G C C G+Y
Sbjct: 869 FGNPLAPNPADKCKACNCNPYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQS 928
Query: 540 GRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKY-PD-CLSCNCD 596
G+ C C+C GST+ C G+C C G C++C ++ + P+ C C+C
Sbjct: 929 GQG--CERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCH 986
Query: 597 VSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQ-FYN--YPACEEC 638
GS+ C D+G C C+ F G +CD C E FYN +P C+EC
Sbjct: 987 PEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 185 bits (451), Expect = 2e-45
Identities = 105/326 (32%), Positives = 150/326 (46%), Gaps = 50/326 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++TC+P VC C+ NT GP C KC G+ + S C+P
Sbjct: 724 CACNGHSETCDPETG-------VCNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQP 772
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C ++ C P+ E C NC T G C C Y+ P G
Sbjct: 773 CPCPGGSS-CAVVPKTKEV--------------VCTNCPTGTTGKRCELCDDGYFGDPLG 817
Query: 350 KRWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP--- 401
+ + +C+ CQC DP+ + GNC +G C +C C C G+F P
Sbjct: 818 RN-GPVRLCRLCQCSDNIDPN-AVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAP 875
Query: 402 ----NCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNC 451
CK C CN GT + C P G C C + G+ C C+ G+Y+ + C+ C
Sbjct: 876 NPADKCKACNCNPYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERC 935
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--PTCKPCNCDTSGTEPSIC 509
+C+ +GS + CD TG C C+ +G+ C +C+ ++ + CKPC+C G+ C
Sbjct: 936 DCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQC 995
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYY 535
D G+C C+ GF G RCDQC Y+
Sbjct: 996 KD-DGRCECREGFVGNRCDQCEENYF 1020
Score = 180 bits (439), Expect = 7e-44
Identities = 109/343 (31%), Positives = 152/343 (44%), Gaps = 39/343 (11%)
Query: 470 CTCKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
CTC Y G+ C C +GY N PC CD +G C C+ GP
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGP 749
Query: 526 RCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTSTSC--SADGKC-NCLTNFGGAQCDQCS 581
C++C GYY G C PC C P GS+ + + C NC T G +C+ C
Sbjct: 750 HCEKCSDGYYGDSTAGTSSDCQPCPC-PGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 582 PGYYKYPD--------CLSCNCDVS---GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQF 629
GY+ P C C C + ++G+ G C C N G CD C++ F
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 630 YNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL 682
+ P C+ CNC+P G + C V G+ C+C V G+ C C P ++NL
Sbjct: 869 FGNPLAPNPADKCKACNCNPYGTMKQQSSCNPV-TGQ-CECLPHVTGQDCGACDPGFYNL 926
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFG 742
Q GCE+C+C+ G+ N G C+ ++GQC C+ + + C++C + G
Sbjct: 927 QSGQ--GCERCDCHALGSTN--GQCDIRTGQCECQPGITGQHCERCEVNHFGFGPE---G 979
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
C CDC GS+ C K G+C C G RCDQ +YF
Sbjct: 980 CKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQ-CEENYF 1020
Score = 175 bits (426), Expect = 2e-42
Identities = 116/370 (31%), Positives = 158/370 (42%), Gaps = 58/370 (15%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS-CEPCNCHNHTTECTYDPEIDEKRLS 312
C C G C C SG+ ++ + N +S C C C+ H+ C DPE
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRE----TPNLGPYSPCVLCACNGHSETC--DPET------ 737
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
G C NC+ NT G +C KC YY D CQPC C S
Sbjct: 738 ----------GVC-NCRDNTAGPHCEKCSDGYYGD-STAGTSSD-CQPCPCPGGSSCAVV 784
Query: 373 EE--ESGRCECRPEFQPPDCSSCAYGYFDYPN--------CKPCTC--NLNGTEGEHCTP 420
+ E C C C GYF P C+ C C N++ +C
Sbjct: 785 PKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNR 844
Query: 421 TDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVSYV--CDKLTGD 469
G C C YN AG C+ C+DG++ + +CK C CN G++ C+ +TG
Sbjct: 845 LTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNPYGTMKQQSSCNPVTGQ 904
Query: 470 CTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPR 526
C C +G+ C C G+YN + C+ C+C G+ CD +GQC C+ G G
Sbjct: 905 CECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQH 964
Query: 527 CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY- 585
C++C ++ G E C PC+C P GS S C DG+C C F G +CDQC Y+
Sbjct: 965 CERCEVNHFG--FGPEG-CKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFY 1021
Query: 586 --KYPDCLSC 593
+P C C
Sbjct: 1022 NRSWPGCQEC 1031
Score = 166 bits (403), Expect = 2e-39
Identities = 109/358 (30%), Positives = 158/358 (44%), Gaps = 52/358 (14%)
Query: 425 CPCKYNYAGKSCEICEDGY---------YSPECKNCECNTVGSVSYVCDKLTGDCTCKSK 475
C C Y G+ CE+C GY YSP C C CN S CD TG C C+
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP-CVLCACN---GHSETCDPETGVCNCRDN 745
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
+G C +C GYY T C+PC C + + C C G G RC+
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 529 QCLSGYYMQVLGRE---RQCVPCNCDPTGSTST--SCS-ADGKC-NCLTNFGGAQCDQCS 581
C GY+ LGR R C C C + +C+ G+C C+ N G CD+C
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCK 865
Query: 582 PGYYKYP-------DCLSCNCDVSGSI--GSTCDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G++ P C +CNC+ G++ S+C+ G C C + G C C FYN
Sbjct: 866 DGFFGNPLAPNPADKCKACNCNPYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYN 925
Query: 632 YPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
+ CE C+C G T G + G+ C+C+ + G+ C C+ ++ + P
Sbjct: 926 LQSGQGCERCDCHALGST---NGQCDIRTGQ-CECQPGITGQHCERCEVNHFG---FGPE 978
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC+ C+C+ G+L+ C G+C C++ +CDQC + ++ GC EC
Sbjct: 979 GCKPCDCHPEGSLSL--QCK-DDGRCECREGFVGNRCDQCEENYF--YNRSWPGCQEC 1031
Score = 122 bits (295), Expect = 2e-26
Identities = 73/232 (31%), Positives = 111/232 (47%), Gaps = 33/232 (14%)
Query: 548 CNCDPTGSTSTSCSADGK-CNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S D CNC N G C++C P + P +CL C+C+
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 597 -------VSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY---NYPACEECNCDPRGV 645
+ + G C +C+ N DGA C+ CRE F+ N AC C+C P G
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
++ C S C CK V G C+ C+P + +L E GC C+C+ +G+++
Sbjct: 406 LST--QCDSYGR---CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-- 455
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNN 757
CN ++G+CVCK +V C++C GF+ L++++ GCT C C S+ N
Sbjct: 456 -CNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 121 bits (291), Expect = 6e-26
Identities = 66/213 (30%), Positives = 95/213 (44%), Gaps = 25/213 (11%)
Query: 451 CECNTVGS--VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP----------TCKPCN 498
C+CN S + DKL C CK G C +C + + P C PC+
Sbjct: 286 CKCNGHASECMKNEFDKLV--CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCD 343
Query: 499 CDTSGTE----PSICDDVS--GQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
C+ E P + G C C+ G C++C ++ LG C C+C
Sbjct: 344 CNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR--LGNNEACSSCHCS 401
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPD--CLSCNCDVSGSIGSTCDDNG 609
P GS ST C + G+C+C G +CD+C PG++ + C C+CD SGSI + G
Sbjct: 402 PVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNVETG 461
Query: 610 LCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
C CK N +G C+ C+ F+N + C P
Sbjct: 462 RCVCKDNVEGFNCERCKPGFFNLESSNPRGCTP 494
Score = 114 bits (274), Expect = 7e-24
Identities = 68/223 (30%), Positives = 99/223 (44%), Gaps = 26/223 (11%)
Query: 361 CQCDPHFSTGNCEE-ESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCN 409
C+C+ H S E + C C+ DC C + D P C PC CN
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 410 LNGTEGE------HCTPTDGLCP-CKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
E T G C C+ N G CE C + ++ + C +C C+ VGS
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
+S CD G C+CK G C++CQ G+++ C+PC+CD SG+ C+ +G+C
Sbjct: 406 LSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNVETGRC 463
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
+CK G C++C G++ R C PC C S T+
Sbjct: 464 VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 94.3 bits (224), Expect = 7e-18
Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 22/185 (11%)
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG---CG 653
D +C+CK N G C+ C F + P C C+C+ R F
Sbjct: 301 DKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS 360
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
+ G C+D G C C+ ++ L N C C+C+ G+L++ C++ G+
Sbjct: 361 TGHGGHCTNCQDNTDGAHCERCRENFFRLG--NNEACSSCHCSPVGSLST--QCDSY-GR 415
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
C CK V +CD+C GF+ L GC C CD GSID C+ TG+C C VEG
Sbjct: 416 CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-CNVETGRCVCKDNVEG 471
Query: 774 RRCDQ 778
C++
Sbjct: 472 FNCER 476
Score = 85.8 bits (203), Expect = 3e-15
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + G C +++ S G C C +GST +C+ GQC C+P + G+ C
Sbjct: 910 HVTGQDCGACDPGFYNLQS--GQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCER 967
Query: 1373 CRTGYYGF--PNCRPCHC-PSTAI---CDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C ++GF C+PC C P ++ C D+G C C + G CD+C+ F G
Sbjct: 968 CEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPG 1027
Query: 1427 CDDC 1430
C +C
Sbjct: 1028 CQEC 1031
Score = 67.3 bits (157), Expect = 1e-09
Identities = 56/227 (24%), Positives = 92/227 (40%), Gaps = 34/227 (14%)
Query: 231 CMCNGHADTC--EPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS 287
C CNG + C +P + C CQ NT G C +C F +R+ N S
Sbjct: 342 CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENF----FRLGNNEACSS 397
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C + +T+C + G+C +C+ G C++C+P ++
Sbjct: 398 CHCSPVGSLSTQC-------------------DSYGRC-SCKPGVMGDKCDRCQPGFHS- 436
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCT 407
E C+PC CDP S C E+GRC C+ + +C C G+F+ + P
Sbjct: 437 ----LTEAG-CRPCSCDPSGSIDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRG 491
Query: 408 CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
C G T+ + Y+ + + +I EDG+ + + E +
Sbjct: 492 CTPCFCFGHSSVCTNAVGYSVYSIS-STFQIDEDGWRAEQRDGSEAS 537
Score = 65.3 bits (152), Expect = 4e-09
Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 29/296 (9%)
Query: 1259 ENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNE 1318
E+F ++K G W+ Y + + T + I E C SP
Sbjct: 158 ESFA-IYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDFSPLT 216
Query: 1319 TG-LCREAMFSITSEYNSGARPCLCDFMGSTELEC-----NTFGGQCPCKPNVIGRTCSA 1372
G + + S YN P L +++ +T++ NTFG + P V+ A
Sbjct: 217 GGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYA 276
Query: 1373 CRTGYYGFPNCRPCHCPSTAICD--DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD- 1429
G C+ S + + D +C C N G +C++C P+ + +R +
Sbjct: 277 ISDFAVG-GRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAES 335
Query: 1430 -CNCNPLGVVGNQLQCEAD---------SGKCA-CRENVRGRVCDHCVPGHYAFPD---C 1475
C P G +C D G C C++N G C+ C + + C
Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEAC 395
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C+ G+ CD + +C CK V G CD C+ + +L + GC C C
Sbjct: 396 SSCHCSPVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTE---AGCRPCSC 447
Score = 42.7 bits (96), Expect = 0.024
Identities = 65/267 (24%), Positives = 106/267 (39%), Gaps = 29/267 (10%)
Query: 2101 DSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSD 2160
DS N I + E L + Q K D ++ ++ E KNLL + +D
Sbjct: 1278 DSETLENEANNIKMEAENLEQLIDQ-KLKDYEDLREDMRGKELEVKNLLEKGKTEQQTAD 1336
Query: 2161 KQISRAAKLAEDAERTLAAVRESAREATEVVKHVADL-------ATGLE--LSQQPKVDS 2211
+ ++RA AE R++ +EA +++ ++ D T E L + P ++
Sbjct: 1337 QLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQ 1396
Query: 2212 ALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRP---- 2267
+TEA + + A + L A N + ER+ VQ KA + R
Sbjct: 1397 TITEANEKTRE-AQQALGSAAADATEA-KNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 2268 -DLKFE------SLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNS 2320
DL E L A +ELK K DD + +A + A+E R +K NS
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAK-----NS 1509
Query: 2321 VTKLNTAAMGDLIDAAYDIGNATYNNM 2347
VT L + + DL++ + N +
Sbjct: 1510 VTSL-LSIINDLLEQLGQLDTVDLNKL 1535
>J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.
Length = 1609
Score = 442 bits (1090), Expect = e-123
Identities = 290/949 (30%), Positives = 439/949 (46%), Gaps = 85/949 (8%)
Query: 1317 NETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQ-CPCKPNVIGRTCSACRT 1375
N+ + + ++I S++ G R C C+ S E N F C CK N G C C
Sbjct: 265 NDPKVLKSYYYAI-SDFAVGGR-CKCNGHAS-ECMKNEFDKLVCNCKHNTYGVDCEKCLP 321
Query: 1376 GYYGFP----------NCRPCHCPSTAI-C----------DDNGMCI-CPKNVEGENCDR 1413
+ P C PC C + C G C C N +G +C+R
Sbjct: 322 FFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCER 381
Query: 1414 CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP 1473
C+ F C C+C+P+G + Q C++ G+C+C+ V G CD C PG ++
Sbjct: 382 CRENFFRLGNNEACSSCHCSPVGSLSTQ--CDS-YGRCSCKPGVMGDKCDRCQPGFHSLT 438
Query: 1474 D--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ C C+C+ G+ D C+ T +C CK NV G C+ CK +FNL+ NP GCT CFC
Sbjct: 439 EAGCRPCSCDPSGSI-DECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Query: 1532 FGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVT 1591
FG ++ C+++ ++ + + +D + E E ++ ++D
Sbjct: 498 FGHSSVCTNA--VGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYF 555
Query: 1592 NGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVE 1651
YF AP +LGK++ SYG L+++ R ++A D+++ G G V +
Sbjct: 556 P---RYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDT--RLSAEDLVLEGA-GLRVSVPLI 609
Query: 1652 QPPVGMPWTHSVK--LSEEEFSTLDGAP-VTRDQFMHALVNISGLYIRASYWEYSIETSL 1708
P +VK E + P +T +F L N++ + IR +Y E S L
Sbjct: 610 AQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGY-L 668
Query: 1709 SNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRL-----PSGFCV 1763
+V L G + AT VE C CP Y G CE C G+ R P CV
Sbjct: 669 DDVTL---ASARPGPGVP---ATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCV 722
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
C CNGHS+ CD TG+C NC DNT G HCE C GY+GD+T GT DC C CP
Sbjct: 723 LCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPG---- 777
Query: 1824 NNFALSCDLSENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN 1882
SC + + C NC G G RCE C GY+G P + C+ C CS N
Sbjct: 778 ---GSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVR-LCRLCQCSDN 833
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIF---SKNCTACICDEFG--- 1936
I+P G+C+ + G+CLKC+ NTAG C+ C GF+G+ + + C AC C+ +G
Sbjct: 834 IDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNPYGTMK 893
Query: 1937 -MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQ 1994
+ C+ TG C C P V G+ C C P + L +G GC C+C + S + QCD GQ
Sbjct: 894 QQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQ 953
Query: 1995 CRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C C G+TG+ C++C + + +GC C+C+ S+ C G+CEC G +G +CD
Sbjct: 954 CECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCD 1013
Query: 2055 RCPERWVLIPQ-EGCLECDSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYIS 2113
+C E + GC EC +C + V D L + + + T + ++
Sbjct: 1014 QCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKL----QELESLIANLGTGDEM--VT 1067
Query: 2114 NQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDA 2173
+Q R K A+ + +D+ +K ++ +NL+ + QISR +
Sbjct: 1068 DQAFEDRLKEAEREVMDLLREAQDVKDVD---QNLMDRLQRVNNTLSSQISRLQNIRNTI 1124
Query: 2174 ERTLAAVRESAREATEVVKHVADLAT-GLELSQQPKVDSALTEARQIRD 2221
E T + E AR E + + ++A+ LE ++ + ++T+ D
Sbjct: 1125 EET-GNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGD 1172
Score = 276 bits (677), Expect = 1e-72
Identities = 146/427 (34%), Positives = 211/427 (49%), Gaps = 31/427 (7%)
Query: 31 TSVCDICDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKY-NEVNLTIDLGQEFHV 85
T C +CDA +H + D TWWQS + G++Y + +NLT+ LG+ F +
Sbjct: 86 TKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDI 145
Query: 86 AYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVI 145
YV +K S RPE + + K T + P+QY+S S ++ + ++ + +
Sbjct: 146 TYVRLKFHTS-RPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQAL 204
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C+ E+S I PL G + S L RPS+ + NS VLQEW AT++R+ T N L
Sbjct: 205 CTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRV----TLNRLNTFG 260
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
DP V + Y+Y+I D ++GGRC CNGHA C + LVC C+HNT G C
Sbjct: 261 DEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASEC----MKNEFDKLVCNCKHNTYGVDC 316
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
KC F + WR + C PC+C+ + EC +DPE+ G GG C
Sbjct: 317 EKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS------TGH---GGHC 367
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
NCQ NT+G +C +CR ++R G + C C C P S + GRC C+P
Sbjct: 368 TNCQDNTDGAHCERCRENFFR-LGNN----EACSSCHCSPVGSLSTQCDSYGRCSCKPGV 422
Query: 386 QPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PC+C+ +G+ E C G C CK N G +CE C+ G+
Sbjct: 423 MGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNVETGRCVCKDNVEGFNCERCKPGF 481
Query: 444 YSPECKN 450
++ E N
Sbjct: 482 FNLESSN 488
Score = 185 bits (451), Expect = 2e-45
Identities = 108/345 (31%), Positives = 156/345 (45%), Gaps = 39/345 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C G C C Y R C C C+ H T C+ E+G C CR
Sbjct: 692 CPVGYGGQFCEMCLSGYRRET-PNLGPYSPCVLCACNGHSET--CDPETGVCNCRDNTAG 748
Query: 388 PDCSSCAYGYFD------YPNCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICE 440
P C C+ GY+ +C+PC C + + +C C GK CE+C+
Sbjct: 749 PHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 441 DGYYSPE---------CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQAGY 488
DGY+ C+ C+C+ + V C++LTG+C C +G C++C+ G+
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 489 YNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
+ P CK CNC+ GT + S C+ V+GQC C G C C G+Y
Sbjct: 869 FGNPLAPNPADKCKACNCNPYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQS 928
Query: 540 GRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKY-PD-CLSCNCD 596
G+ C C+C GST+ C G+C C G C++C ++ + P+ C C+C
Sbjct: 929 GQG--CERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCH 986
Query: 597 VSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQ-FYN--YPACEEC 638
GS+ C D+G C C+ F G +CD C E FYN +P C+EC
Sbjct: 987 PEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 185 bits (451), Expect = 2e-45
Identities = 105/326 (32%), Positives = 150/326 (46%), Gaps = 50/326 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++TC+P VC C+ NT GP C KC G+ + S C+P
Sbjct: 724 CACNGHSETCDPETG-------VCNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQP 772
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C ++ C P+ E C NC T G C C Y+ P G
Sbjct: 773 CPCPGGSS-CAVVPKTKEV--------------VCTNCPTGTTGKRCELCDDGYFGDPLG 817
Query: 350 KRWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP--- 401
+ + +C+ CQC DP+ + GNC +G C +C C C G+F P
Sbjct: 818 RN-GPVRLCRLCQCSDNIDPN-AVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAP 875
Query: 402 ----NCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNC 451
CK C CN GT + C P G C C + G+ C C+ G+Y+ + C+ C
Sbjct: 876 NPADKCKACNCNPYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERC 935
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--PTCKPCNCDTSGTEPSIC 509
+C+ +GS + CD TG C C+ +G+ C +C+ ++ + CKPC+C G+ C
Sbjct: 936 DCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQC 995
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYY 535
D G+C C+ GF G RCDQC Y+
Sbjct: 996 KD-DGRCECREGFVGNRCDQCEENYF 1020
Score = 180 bits (439), Expect = 7e-44
Identities = 109/343 (31%), Positives = 152/343 (44%), Gaps = 39/343 (11%)
Query: 470 CTCKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
CTC Y G+ C C +GY N PC CD +G C C+ GP
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGP 749
Query: 526 RCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTSTSC--SADGKC-NCLTNFGGAQCDQCS 581
C++C GYY G C PC C P GS+ + + C NC T G +C+ C
Sbjct: 750 HCEKCSDGYYGDSTAGTSSDCQPCPC-PGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 582 PGYYKYPD--------CLSCNCDVS---GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQF 629
GY+ P C C C + ++G+ G C C N G CD C++ F
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 630 YNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL 682
+ P C+ CNC+P G + C V G+ C+C V G+ C C P ++NL
Sbjct: 869 FGNPLAPNPADKCKACNCNPYGTMKQQSSCNPV-TGQ-CECLPHVTGQDCGACDPGFYNL 926
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFG 742
Q GCE+C+C+ G+ N G C+ ++GQC C+ + + C++C + G
Sbjct: 927 QSGQ--GCERCDCHALGSTN--GQCDIRTGQCECQPGITGQHCERCEVNHFGFGPE---G 979
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
C CDC GS+ C K G+C C G RCDQ +YF
Sbjct: 980 CKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQ-CEENYF 1020
Score = 175 bits (426), Expect = 2e-42
Identities = 116/370 (31%), Positives = 158/370 (42%), Gaps = 58/370 (15%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS-CEPCNCHNHTTECTYDPEIDEKRLS 312
C C G C C SG+ ++ + N +S C C C+ H+ C DPE
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRE----TPNLGPYSPCVLCACNGHSETC--DPET------ 737
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
G C NC+ NT G +C KC YY D CQPC C S
Sbjct: 738 ----------GVC-NCRDNTAGPHCEKCSDGYYGD-STAGTSSD-CQPCPCPGGSSCAVV 784
Query: 373 EE--ESGRCECRPEFQPPDCSSCAYGYFDYPN--------CKPCTC--NLNGTEGEHCTP 420
+ E C C C GYF P C+ C C N++ +C
Sbjct: 785 PKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNR 844
Query: 421 TDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVSYV--CDKLTGD 469
G C C YN AG C+ C+DG++ + +CK C CN G++ C+ +TG
Sbjct: 845 LTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNPYGTMKQQSSCNPVTGQ 904
Query: 470 CTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPR 526
C C +G+ C C G+YN + C+ C+C G+ CD +GQC C+ G G
Sbjct: 905 CECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQH 964
Query: 527 CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY- 585
C++C ++ G E C PC+C P GS S C DG+C C F G +CDQC Y+
Sbjct: 965 CERCEVNHFG--FGPEG-CKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFY 1021
Query: 586 --KYPDCLSC 593
+P C C
Sbjct: 1022 NRSWPGCQEC 1031
Score = 166 bits (403), Expect = 2e-39
Identities = 109/358 (30%), Positives = 158/358 (44%), Gaps = 52/358 (14%)
Query: 425 CPCKYNYAGKSCEICEDGY---------YSPECKNCECNTVGSVSYVCDKLTGDCTCKSK 475
C C Y G+ CE+C GY YSP C C CN S CD TG C C+
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP-CVLCACN---GHSETCDPETGVCNCRDN 745
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
+G C +C GYY T C+PC C + + C C G G RC+
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 529 QCLSGYYMQVLGRE---RQCVPCNCDPTGSTST--SCS-ADGKC-NCLTNFGGAQCDQCS 581
C GY+ LGR R C C C + +C+ G+C C+ N G CD+C
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCK 865
Query: 582 PGYYKYP-------DCLSCNCDVSGSI--GSTCDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G++ P C +CNC+ G++ S+C+ G C C + G C C FYN
Sbjct: 866 DGFFGNPLAPNPADKCKACNCNPYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYN 925
Query: 632 YPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
+ CE C+C G T G + G+ C+C+ + G+ C C+ ++ + P
Sbjct: 926 LQSGQGCERCDCHALGST---NGQCDIRTGQ-CECQPGITGQHCERCEVNHFG---FGPE 978
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC+ C+C+ G+L+ C G+C C++ +CDQC + ++ GC EC
Sbjct: 979 GCKPCDCHPEGSLSL--QCK-DDGRCECREGFVGNRCDQCEENYF--YNRSWPGCQEC 1031
Score = 122 bits (295), Expect = 2e-26
Identities = 73/232 (31%), Positives = 111/232 (47%), Gaps = 33/232 (14%)
Query: 548 CNCDPTGSTSTSCSADGK-CNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S D CNC N G C++C P + P +CL C+C+
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 597 -------VSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY---NYPACEECNCDPRGV 645
+ + G C +C+ N DGA C+ CRE F+ N AC C+C P G
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
++ C S C CK V G C+ C+P + +L E GC C+C+ +G+++
Sbjct: 406 LST--QCDSYGR---CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-- 455
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNN 757
CN ++G+CVCK +V C++C GF+ L++++ GCT C C S+ N
Sbjct: 456 -CNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 121 bits (291), Expect = 6e-26
Identities = 66/213 (30%), Positives = 95/213 (44%), Gaps = 25/213 (11%)
Query: 451 CECNTVGS--VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP----------TCKPCN 498
C+CN S + DKL C CK G C +C + + P C PC+
Sbjct: 286 CKCNGHASECMKNEFDKLV--CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCD 343
Query: 499 CDTSGTE----PSICDDVS--GQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
C+ E P + G C C+ G C++C ++ LG C C+C
Sbjct: 344 CNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR--LGNNEACSSCHCS 401
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPD--CLSCNCDVSGSIGSTCDDNG 609
P GS ST C + G+C+C G +CD+C PG++ + C C+CD SGSI + G
Sbjct: 402 PVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNVETG 461
Query: 610 LCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
C CK N +G C+ C+ F+N + C P
Sbjct: 462 RCVCKDNVEGFNCERCKPGFFNLESSNPRGCTP 494
Score = 114 bits (274), Expect = 7e-24
Identities = 68/223 (30%), Positives = 99/223 (44%), Gaps = 26/223 (11%)
Query: 361 CQCDPHFSTGNCEE-ESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCN 409
C+C+ H S E + C C+ DC C + D P C PC CN
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 410 LNGTEGE------HCTPTDGLCP-CKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
E T G C C+ N G CE C + ++ + C +C C+ VGS
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
+S CD G C+CK G C++CQ G+++ C+PC+CD SG+ C+ +G+C
Sbjct: 406 LSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNVETGRC 463
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
+CK G C++C G++ R C PC C S T+
Sbjct: 464 VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 94.3 bits (224), Expect = 7e-18
Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 22/185 (11%)
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG---CG 653
D +C+CK N G C+ C F + P C C+C+ R F
Sbjct: 301 DKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS 360
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
+ G C+D G C C+ ++ L N C C+C+ G+L++ C++ G+
Sbjct: 361 TGHGGHCTNCQDNTDGAHCERCRENFFRLG--NNEACSSCHCSPVGSLST--QCDSY-GR 415
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
C CK V +CD+C GF+ L GC C CD GSID C+ TG+C C VEG
Sbjct: 416 CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-CNVETGRCVCKDNVEG 471
Query: 774 RRCDQ 778
C++
Sbjct: 472 FNCER 476
Score = 85.8 bits (203), Expect = 3e-15
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + G C +++ S G C C +GST +C+ GQC C+P + G+ C
Sbjct: 910 HVTGQDCGACDPGFYNLQS--GQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCER 967
Query: 1373 CRTGYYGF--PNCRPCHC-PSTAI---CDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C ++GF C+PC C P ++ C D+G C C + G CD+C+ F G
Sbjct: 968 CEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPG 1027
Query: 1427 CDDC 1430
C +C
Sbjct: 1028 CQEC 1031
Score = 67.3 bits (157), Expect = 1e-09
Identities = 56/227 (24%), Positives = 92/227 (40%), Gaps = 34/227 (14%)
Query: 231 CMCNGHADTC--EPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS 287
C CNG + C +P + C CQ NT G C +C F +R+ N S
Sbjct: 342 CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENF----FRLGNNEACSS 397
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C + +T+C + G+C +C+ G C++C+P ++
Sbjct: 398 CHCSPVGSLSTQC-------------------DSYGRC-SCKPGVMGDKCDRCQPGFHS- 436
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCT 407
E C+PC CDP S C E+GRC C+ + +C C G+F+ + P
Sbjct: 437 ----LTEAG-CRPCSCDPSGSIDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRG 491
Query: 408 CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
C G T+ + Y+ + + +I EDG+ + + E +
Sbjct: 492 CTPCFCFGHSSVCTNAVGYSVYSIS-STFQIDEDGWRAEQRDGSEAS 537
Score = 66.9 bits (156), Expect = 1e-09
Identities = 70/296 (23%), Positives = 112/296 (37%), Gaps = 29/296 (9%)
Query: 1259 ENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNE 1318
E+F ++K G W+ Y + + T + I E C ISP
Sbjct: 158 ESFA-IYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLT 216
Query: 1319 TG-LCREAMFSITSEYNSGARPCLCDFMGSTELEC-----NTFGGQCPCKPNVIGRTCSA 1372
G + + S YN P L +++ +T++ NTFG + P V+ A
Sbjct: 217 GGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYA 276
Query: 1373 CRTGYYGFPNCRPCHCPSTAICD--DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD- 1429
G C+ S + + D +C C N G +C++C P+ + +R +
Sbjct: 277 ISDFAVG-GRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAES 335
Query: 1430 -CNCNPLGVVGNQLQCEAD---------SGKCA-CRENVRGRVCDHCVPGHYAFPD---C 1475
C P G +C D G C C++N G C+ C + + C
Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEAC 395
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C+ G+ CD + +C CK V G CD C+ + +L + GC C C
Sbjct: 396 SSCHCSPVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTE---AGCRPCSC 447
Score = 42.7 bits (96), Expect = 0.024
Identities = 65/267 (24%), Positives = 106/267 (39%), Gaps = 29/267 (10%)
Query: 2101 DSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSD 2160
DS N I + E L + Q K D ++ ++ E KNLL + +D
Sbjct: 1278 DSETLENEANNIKMEAENLEQLIDQ-KLKDYEDLREDMRGKELEVKNLLEKGKTEQQTAD 1336
Query: 2161 KQISRAAKLAEDAERTLAAVRESAREATEVVKHVADL-------ATGLE--LSQQPKVDS 2211
+ ++RA AE R++ +EA +++ ++ D T E L + P ++
Sbjct: 1337 QLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQ 1396
Query: 2212 ALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRP---- 2267
+TEA + + A + L A N + ER+ VQ KA + R
Sbjct: 1397 TITEANEKTRE-AQQALGSAAADATEA-KNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 2268 -DLKFE------SLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNS 2320
DL E L A +ELK K DD + +A + A+E R +K NS
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAK-----NS 1509
Query: 2321 VTKLNTAAMGDLIDAAYDIGNATYNNM 2347
VT L + + DL++ + N +
Sbjct: 1510 VTSL-LSIINDLLEQLGQLDTVDLNKL 1535
>AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 441 bits (1087), Expect = e-122
Identities = 290/949 (30%), Positives = 439/949 (46%), Gaps = 85/949 (8%)
Query: 1317 NETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQ-CPCKPNVIGRTCSACRT 1375
N+ + + ++I S++ G R C C+ S E N F C CK N G C C
Sbjct: 265 NDPKVLKSYYYAI-SDFAVGGR-CKCNGHAS-ECMKNEFDKLVCNCKHNTYGVDCEKCLP 321
Query: 1376 GYYGFP----------NCRPCHCPSTAI-C----------DDNGMCI-CPKNVEGENCDR 1413
+ P C PC C + C G C C N +G +C+R
Sbjct: 322 FFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCER 381
Query: 1414 CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP 1473
C+ F C C+C+P+G + Q C++ G+C+C+ V G CD C PG ++
Sbjct: 382 CRENFFRLGNNEACSSCHCSPVGSLSTQ--CDS-YGRCSCKPGVMGDKCDRCQPGFHSLT 438
Query: 1474 D--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ C C+C+ G+ D C+ T +C CK NV G C+ CK +FNL+ NP GCT CFC
Sbjct: 439 EAGCRPCSCDPSGSI-DECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Query: 1532 FGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVT 1591
FG ++ C+++ ++ + + +D + E E ++ ++D
Sbjct: 498 FGHSSVCTNA--VGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYF 555
Query: 1592 NGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVE 1651
YF AP +LGK++ SYG L+++ R ++A D+++ G G V +
Sbjct: 556 P---RYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDT--RLSAEDLVLEGA-GLRVSVPLI 609
Query: 1652 QPPVGMPWTHSVK--LSEEEFSTLDGAP-VTRDQFMHALVNISGLYIRASYWEYSIETSL 1708
P +VK E + P +T +F L N++ + IR +Y E S L
Sbjct: 610 AQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGY-L 668
Query: 1709 SNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRL-----PSGFCV 1763
+V L G + AT VE C CP Y G CE C G+ R P CV
Sbjct: 669 DDVTL---ASARPGPGVP---ATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCV 722
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
C CNGHS+ CD TG+C NC DNT G HCE C GY+GD+T GT DC C CP
Sbjct: 723 LCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPG---- 777
Query: 1824 NNFALSCDLSENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN 1882
SC + + C NC G G RCE C GY+G P + C+ C CS N
Sbjct: 778 ---GSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVR-LCRLCQCSDN 833
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIF---SKNCTACICDEFG--- 1936
I+P G+C+ + G+CLKC+ NTAG C+ C GF+G+ + + C AC C+ +G
Sbjct: 834 IDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMK 893
Query: 1937 -MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQ 1994
+ C+ TG C C P V G+ C C P + L +G GC C+C + S + QCD GQ
Sbjct: 894 QQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQ 953
Query: 1995 CRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C C G+TG+ C++C + + +GC C+C+ S+ C G+CEC G +G +CD
Sbjct: 954 CECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCD 1013
Query: 2055 RCPERWVLIPQ-EGCLECDSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYIS 2113
+C E + GC EC +C + V D L + + + T + ++
Sbjct: 1014 QCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKL----QELESLIANLGTGDEM--VT 1067
Query: 2114 NQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDA 2173
+Q R K A+ + +D+ +K ++ +NL+ + QISR +
Sbjct: 1068 DQAFEDRLKEAEREVMDLLREAQDVKDVD---QNLMDRLQRVNNTLSSQISRLQNIRNTI 1124
Query: 2174 ERTLAAVRESAREATEVVKHVADLAT-GLELSQQPKVDSALTEARQIRD 2221
E T + E AR E + + ++A+ LE ++ + ++T+ D
Sbjct: 1125 EET-GNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGD 1172
Score = 276 bits (676), Expect = 1e-72
Identities = 146/427 (34%), Positives = 211/427 (49%), Gaps = 31/427 (7%)
Query: 31 TSVCDICDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKY-NEVNLTIDLGQEFHV 85
T C +CDA +H + D TWWQS + G++Y + +NLT+ LG+ F +
Sbjct: 86 TKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDI 145
Query: 86 AYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVI 145
YV +K S RPE + + K T + P+QY+S S ++ + ++ + +
Sbjct: 146 TYVRLKFHTS-RPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQAL 204
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C+ E+S I PL G + S L RPS+ + NS VLQEW AT++R+ T N L
Sbjct: 205 CTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRV----TLNRLNTFG 260
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
DP V + Y+Y+I D ++GGRC CNGHA C + LVC C+HNT G C
Sbjct: 261 DEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASEC----MKNEFDKLVCNCKHNTYGVDC 316
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
KC F + WR + C PC+C+ + EC +DPE+ G GG C
Sbjct: 317 EKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS------TGH---GGHC 367
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
NCQ NT+G +C +CR ++R G + C C C P S + GRC C+P
Sbjct: 368 TNCQDNTDGAHCERCRENFFR-LGNN----EACSSCHCSPVGSLSTQCDSYGRCSCKPGV 422
Query: 386 QPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PC+C+ +G+ E C G C CK N G +CE C+ G+
Sbjct: 423 MGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETGRCVCKDNVEGFNCERCKPGF 481
Query: 444 YSPECKN 450
++ E N
Sbjct: 482 FNLESSN 488
Score = 188 bits (458), Expect = 3e-46
Identities = 106/326 (32%), Positives = 151/326 (46%), Gaps = 50/326 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++TC+P VC C+ NT GP C KC G+ + S C+P
Sbjct: 724 CACNGHSETCDPETG-------VCNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQP 772
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C ++ C P+ E C NC T G C C Y+ P G
Sbjct: 773 CPCPGGSS-CAVVPKTKEV--------------VCTNCPTGTTGKRCELCDDGYFGDPLG 817
Query: 350 KRWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP--- 401
+ + +C+ CQC DP+ + GNC +G C +C C C G+F P
Sbjct: 818 RN-GPVRLCRLCQCSDNIDPN-AVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAP 875
Query: 402 ----NCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNC 451
CK C CNL GT + C P G C C + G+ C C+ G+Y+ + C+ C
Sbjct: 876 NPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERC 935
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--PTCKPCNCDTSGTEPSIC 509
+C+ +GS + CD TG C C+ +G+ C +C+ ++ + CKPC+C G+ C
Sbjct: 936 DCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQC 995
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYY 535
D G+C C+ GF G RCDQC Y+
Sbjct: 996 KD-DGRCECREGFVGNRCDQCEENYF 1020
Score = 185 bits (451), Expect = 2e-45
Identities = 108/345 (31%), Positives = 156/345 (45%), Gaps = 39/345 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C G C C Y R C C C+ H T C+ E+G C CR
Sbjct: 692 CPVGYGGQFCEMCLSGYRRET-PNLGPYSPCVLCACNGHSET--CDPETGVCNCRDNTAG 748
Query: 388 PDCSSCAYGYFD------YPNCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICE 440
P C C+ GY+ +C+PC C + + +C C GK CE+C+
Sbjct: 749 PHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 441 DGYYSPE---------CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQAGY 488
DGY+ C+ C+C+ + V C++LTG+C C +G C++C+ G+
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 489 YNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
+ P CK CNC+ GT + S C+ V+GQC C G C C G+Y
Sbjct: 869 FGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQS 928
Query: 540 GRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKY-PD-CLSCNCD 596
G+ C C+C GST+ C G+C C G C++C ++ + P+ C C+C
Sbjct: 929 GQG--CERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCH 986
Query: 597 VSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQ-FYN--YPACEEC 638
GS+ C D+G C C+ F G +CD C E FYN +P C+EC
Sbjct: 987 PEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 176 bits (429), Expect = 1e-42
Identities = 108/343 (31%), Positives = 151/343 (44%), Gaps = 39/343 (11%)
Query: 470 CTCKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
CTC Y G+ C C +GY N PC CD +G C C+ GP
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGP 749
Query: 526 RCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTSTSC--SADGKC-NCLTNFGGAQCDQCS 581
C++C GYY G C PC C P GS+ + + C NC T G +C+ C
Sbjct: 750 HCEKCSDGYYGDSTAGTSSDCQPCPC-PGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 582 PGYYKYPD--------CLSCNCDVS---GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQF 629
GY+ P C C C + ++G+ G C C N G CD C++ F
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 630 YNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL 682
+ P C+ CNC+ G + C V G+ C+C V G+ C C P ++NL
Sbjct: 869 FGNPLAPNPADKCKACNCNLYGTMKQQSSCNPV-TGQ-CECLPHVTGQDCGACDPGFYNL 926
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFG 742
Q GCE+C+C+ G+ N G C+ ++GQC C+ + + C++C + G
Sbjct: 927 QSGQ--GCERCDCHALGSTN--GQCDIRTGQCECQPGITGQHCERCEVNHFGFGPE---G 979
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
C CDC GS+ C K G+C C G RCDQ +YF
Sbjct: 980 CKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQ-CEENYF 1020
Score = 175 bits (426), Expect = 2e-42
Identities = 116/370 (31%), Positives = 158/370 (42%), Gaps = 58/370 (15%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS-CEPCNCHNHTTECTYDPEIDEKRLS 312
C C G C C SG+ ++ + N +S C C C+ H+ C DPE
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRE----TPNLGPYSPCVLCACNGHSETC--DPET------ 737
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
G C NC+ NT G +C KC YY D CQPC C S
Sbjct: 738 ----------GVC-NCRDNTAGPHCEKCSDGYYGD-STAGTSSD-CQPCPCPGGSSCAVV 784
Query: 373 EE--ESGRCECRPEFQPPDCSSCAYGYFDYPN--------CKPCTC--NLNGTEGEHCTP 420
+ E C C C GYF P C+ C C N++ +C
Sbjct: 785 PKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNR 844
Query: 421 TDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVSYV--CDKLTGD 469
G C C YN AG C+ C+DG++ + +CK C CN G++ C+ +TG
Sbjct: 845 LTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQ 904
Query: 470 CTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPR 526
C C +G+ C C G+YN + C+ C+C G+ CD +GQC C+ G G
Sbjct: 905 CECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQH 964
Query: 527 CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY- 585
C++C ++ G E C PC+C P GS S C DG+C C F G +CDQC Y+
Sbjct: 965 CERCEVNHFG--FGPEG-CKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFY 1021
Query: 586 --KYPDCLSC 593
+P C C
Sbjct: 1022 NRSWPGCQEC 1031
Score = 167 bits (406), Expect = 7e-40
Identities = 109/358 (30%), Positives = 159/358 (44%), Gaps = 52/358 (14%)
Query: 425 CPCKYNYAGKSCEICEDGY---------YSPECKNCECNTVGSVSYVCDKLTGDCTCKSK 475
C C Y G+ CE+C GY YSP C C CN S CD TG C C+
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP-CVLCACN---GHSETCDPETGVCNCRDN 745
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
+G C +C GYY T C+PC C + + C C G G RC+
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 529 QCLSGYYMQVLGRE---RQCVPCNCDPTGSTST--SCS-ADGKC-NCLTNFGGAQCDQCS 581
C GY+ LGR R C C C + +C+ G+C C+ N G CD+C
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCK 865
Query: 582 PGYYKYP-------DCLSCNCDVSGSI--GSTCDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G++ P C +CNC++ G++ S+C+ G C C + G C C FYN
Sbjct: 866 DGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYN 925
Query: 632 YPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
+ CE C+C G T G + G+ C+C+ + G+ C C+ ++ + P
Sbjct: 926 LQSGQGCERCDCHALGST---NGQCDIRTGQ-CECQPGITGQHCERCEVNHFG---FGPE 978
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC+ C+C+ G+L+ C G+C C++ +CDQC + ++ GC EC
Sbjct: 979 GCKPCDCHPEGSLSL--QCK-DDGRCECREGFVGNRCDQCEENYF--YNRSWPGCQEC 1031
Score = 122 bits (294), Expect = 2e-26
Identities = 73/232 (31%), Positives = 111/232 (47%), Gaps = 33/232 (14%)
Query: 548 CNCDPTGSTSTSCSADGK-CNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S D CNC N G C++C P + P +CL C+C+
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 597 -------VSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY---NYPACEECNCDPRGV 645
+ + G C +C+ N DGA C+ CRE F+ N AC C+C P G
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
++ C S C CK V G C+ C+P + +L E GC C+C+ +G+++
Sbjct: 406 LST--QCDSYGR---CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-- 455
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNN 757
CN ++G+CVCK +V C++C GF+ L++++ GCT C C S+ N
Sbjct: 456 -CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 121 bits (291), Expect = 6e-26
Identities = 66/213 (30%), Positives = 95/213 (44%), Gaps = 25/213 (11%)
Query: 451 CECNTVGS--VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP----------TCKPCN 498
C+CN S + DKL C CK G C +C + + P C PC+
Sbjct: 286 CKCNGHASECMKNEFDKLV--CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCD 343
Query: 499 CDTSGTE----PSICDDVS--GQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
C+ E P + G C C+ G C++C ++ LG C C+C
Sbjct: 344 CNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR--LGNNEACSSCHCS 401
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPD--CLSCNCDVSGSIGSTCDDNG 609
P GS ST C + G+C+C G +CD+C PG++ + C C+CD SGSI + G
Sbjct: 402 PVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETG 461
Query: 610 LCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
C CK N +G C+ C+ F+N + C P
Sbjct: 462 RCVCKDNVEGFNCERCKPGFFNLESSNPRGCTP 494
Score = 114 bits (274), Expect = 7e-24
Identities = 68/223 (30%), Positives = 99/223 (44%), Gaps = 26/223 (11%)
Query: 361 CQCDPHFSTGNCEE-ESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCN 409
C+C+ H S E + C C+ DC C + D P C PC CN
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 410 LNGTEGE------HCTPTDGLCP-CKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
E T G C C+ N G CE C + ++ + C +C C+ VGS
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
+S CD G C+CK G C++CQ G+++ C+PC+CD SG+ C+ +G+C
Sbjct: 406 LSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETGRC 463
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
+CK G C++C G++ R C PC C S T+
Sbjct: 464 VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 93.9 bits (223), Expect = 1e-17
Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 22/185 (11%)
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG---CG 653
D +C+CK N G C+ C F + P C C+C+ R F
Sbjct: 301 DKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS 360
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
+ G C+D G C C+ ++ L N C C+C+ G+L++ C++ G+
Sbjct: 361 TGHGGHCTNCQDNTDGAHCERCRENFFRLG--NNEACSSCHCSPVGSLST--QCDSY-GR 415
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
C CK V +CD+C GF+ L GC C CD GSID C+ TG+C C VEG
Sbjct: 416 CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-CNIETGRCVCKDNVEG 471
Query: 774 RRCDQ 778
C++
Sbjct: 472 FNCER 476
Score = 85.8 bits (203), Expect = 3e-15
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + G C +++ S G C C +GST +C+ GQC C+P + G+ C
Sbjct: 910 HVTGQDCGACDPGFYNLQS--GQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCER 967
Query: 1373 CRTGYYGF--PNCRPCHC-PSTAI---CDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C ++GF C+PC C P ++ C D+G C C + G CD+C+ F G
Sbjct: 968 CEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPG 1027
Query: 1427 CDDC 1430
C +C
Sbjct: 1028 CQEC 1031
Score = 66.9 bits (156), Expect = 1e-09
Identities = 70/296 (23%), Positives = 112/296 (37%), Gaps = 29/296 (9%)
Query: 1259 ENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNE 1318
E+F ++K G W+ Y + + T + I E C ISP
Sbjct: 158 ESFA-IYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLT 216
Query: 1319 TG-LCREAMFSITSEYNSGARPCLCDFMGSTELEC-----NTFGGQCPCKPNVIGRTCSA 1372
G + + S YN P L +++ +T++ NTFG + P V+ A
Sbjct: 217 GGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYA 276
Query: 1373 CRTGYYGFPNCRPCHCPSTAICD--DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD- 1429
G C+ S + + D +C C N G +C++C P+ + +R +
Sbjct: 277 ISDFAVG-GRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAES 335
Query: 1430 -CNCNPLGVVGNQLQCEAD---------SGKCA-CRENVRGRVCDHCVPGHYAFPD---C 1475
C P G +C D G C C++N G C+ C + + C
Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEAC 395
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C+ G+ CD + +C CK V G CD C+ + +L + GC C C
Sbjct: 396 SSCHCSPVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTE---AGCRPCSC 447
Score = 66.9 bits (156), Expect = 1e-09
Identities = 56/227 (24%), Positives = 92/227 (40%), Gaps = 34/227 (14%)
Query: 231 CMCNGHADTC--EPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS 287
C CNG + C +P + C CQ NT G C +C F +R+ N S
Sbjct: 342 CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENF----FRLGNNEACSS 397
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C + +T+C + G+C +C+ G C++C+P ++
Sbjct: 398 CHCSPVGSLSTQC-------------------DSYGRC-SCKPGVMGDKCDRCQPGFHS- 436
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCT 407
E C+PC CDP S C E+GRC C+ + +C C G+F+ + P
Sbjct: 437 ----LTEAG-CRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRG 491
Query: 408 CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
C G T+ + Y+ + + +I EDG+ + + E +
Sbjct: 492 CTPCFCFGHSSVCTNAVGYSVYSIS-STFQIDEDGWRAEQRDGSEAS 537
Score = 42.7 bits (96), Expect = 0.024
Identities = 65/267 (24%), Positives = 106/267 (39%), Gaps = 29/267 (10%)
Query: 2101 DSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSD 2160
DS N I + E L + Q K D ++ ++ E KNLL + +D
Sbjct: 1278 DSETLENEANNIKMEAENLEQLIDQ-KLKDYEDLREDMRGKELEVKNLLEKGKTEQQTAD 1336
Query: 2161 KQISRAAKLAEDAERTLAAVRESAREATEVVKHVADL-------ATGLE--LSQQPKVDS 2211
+ ++RA AE R++ +EA +++ ++ D T E L + P ++
Sbjct: 1337 QLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQ 1396
Query: 2212 ALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRP---- 2267
+TEA + + A + L A N + ER+ VQ KA + R
Sbjct: 1397 TITEANEKTRE-AQQALGSAAADATEA-KNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 2268 -DLKFE------SLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNS 2320
DL E L A +ELK K DD + +A + A+E R +K NS
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAK-----NS 1509
Query: 2321 VTKLNTAAMGDLIDAAYDIGNATYNNM 2347
VT L + + DL++ + N +
Sbjct: 1510 VTSL-LSIINDLLEQLGQLDTVDLNKL 1535
>AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 441 bits (1087), Expect = e-122
Identities = 290/949 (30%), Positives = 439/949 (46%), Gaps = 85/949 (8%)
Query: 1317 NETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQ-CPCKPNVIGRTCSACRT 1375
N+ + + ++I S++ G R C C+ S E N F C CK N G C C
Sbjct: 265 NDPKVLKSYYYAI-SDFAVGGR-CKCNGHAS-ECMKNEFDKLVCNCKHNTYGVDCEKCLP 321
Query: 1376 GYYGFP----------NCRPCHCPSTAI-C----------DDNGMCI-CPKNVEGENCDR 1413
+ P C PC C + C G C C N +G +C+R
Sbjct: 322 FFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCER 381
Query: 1414 CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP 1473
C+ F C C+C+P+G + Q C++ G+C+C+ V G CD C PG ++
Sbjct: 382 CRENFFRLGNNEACSSCHCSPVGSLSTQ--CDS-YGRCSCKPGVMGDKCDRCQPGFHSLT 438
Query: 1474 D--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ C C+C+ G+ D C+ T +C CK NV G C+ CK +FNL+ NP GCT CFC
Sbjct: 439 EAGCRPCSCDPSGSI-DECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Query: 1532 FGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVT 1591
FG ++ C+++ ++ + + +D + E E ++ ++D
Sbjct: 498 FGHSSVCTNA--VGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYF 555
Query: 1592 NGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVE 1651
YF AP +LGK++ SYG L+++ R ++A D+++ G G V +
Sbjct: 556 P---RYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDT--RLSAEDLVLEGA-GLRVSVPLI 609
Query: 1652 QPPVGMPWTHSVK--LSEEEFSTLDGAP-VTRDQFMHALVNISGLYIRASYWEYSIETSL 1708
P +VK E + P +T +F L N++ + IR +Y E S L
Sbjct: 610 AQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGY-L 668
Query: 1709 SNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRL-----PSGFCV 1763
+V L G + AT VE C CP Y G CE C G+ R P CV
Sbjct: 669 DDVTL---ASARPGPGVP---ATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCV 722
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
C CNGHS+ CD TG+C NC DNT G HCE C GY+GD+T GT DC C CP
Sbjct: 723 LCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPG---- 777
Query: 1824 NNFALSCDLSENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN 1882
SC + + C NC G G RCE C GY+G P + C+ C CS N
Sbjct: 778 ---GSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVR-LCRLCQCSDN 833
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIF---SKNCTACICDEFG--- 1936
I+P G+C+ + G+CLKC+ NTAG C+ C GF+G+ + + C AC C+ +G
Sbjct: 834 IDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMK 893
Query: 1937 -MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQ 1994
+ C+ TG C C P V G+ C C P + L +G GC C+C + S + QCD GQ
Sbjct: 894 QQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQ 953
Query: 1995 CRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C C G+TG+ C++C + + +GC C+C+ S+ C G+CEC G +G +CD
Sbjct: 954 CECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCD 1013
Query: 2055 RCPERWVLIPQ-EGCLECDSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYIS 2113
+C E + GC EC +C + V D L + + + T + ++
Sbjct: 1014 QCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKL----QELESLIANLGTGDEM--VT 1067
Query: 2114 NQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDA 2173
+Q R K A+ + +D+ +K ++ +NL+ + QISR +
Sbjct: 1068 DQAFEDRLKEAEREVMDLLREAQDVKDVD---QNLMDRLQRVNNTLSSQISRLQNIRNTI 1124
Query: 2174 ERTLAAVRESAREATEVVKHVADLAT-GLELSQQPKVDSALTEARQIRD 2221
E T + E AR E + + ++A+ LE ++ + ++T+ D
Sbjct: 1125 EET-GNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGD 1172
Score = 276 bits (676), Expect = 1e-72
Identities = 146/427 (34%), Positives = 211/427 (49%), Gaps = 31/427 (7%)
Query: 31 TSVCDICDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKY-NEVNLTIDLGQEFHV 85
T C +CDA +H + D TWWQS + G++Y + +NLT+ LG+ F +
Sbjct: 86 TKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDI 145
Query: 86 AYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVI 145
YV +K S RPE + + K T + P+QY+S S ++ + ++ + +
Sbjct: 146 TYVRLKFHTS-RPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQAL 204
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C+ E+S I PL G + S L RPS+ + NS VLQEW AT++R+ T N L
Sbjct: 205 CTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRV----TLNRLNTFG 260
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
DP V + Y+Y+I D ++GGRC CNGHA C + LVC C+HNT G C
Sbjct: 261 DEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASEC----MKNEFDKLVCNCKHNTYGVDC 316
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
KC F + WR + C PC+C+ + EC +DPE+ G GG C
Sbjct: 317 EKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS------TGH---GGHC 367
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
NCQ NT+G +C +CR ++R G + C C C P S + GRC C+P
Sbjct: 368 TNCQDNTDGAHCERCRENFFR-LGNN----EACSSCHCSPVGSLSTQCDSYGRCSCKPGV 422
Query: 386 QPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PC+C+ +G+ E C G C CK N G +CE C+ G+
Sbjct: 423 MGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETGRCVCKDNVEGFNCERCKPGF 481
Query: 444 YSPECKN 450
++ E N
Sbjct: 482 FNLESSN 488
Score = 188 bits (458), Expect = 3e-46
Identities = 106/326 (32%), Positives = 151/326 (46%), Gaps = 50/326 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++TC+P VC C+ NT GP C KC G+ + S C+P
Sbjct: 724 CACNGHSETCDPETG-------VCNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQP 772
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C ++ C P+ E C NC T G C C Y+ P G
Sbjct: 773 CPCPGGSS-CAVVPKTKEV--------------VCTNCPTGTTGKRCELCDDGYFGDPLG 817
Query: 350 KRWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP--- 401
+ + +C+ CQC DP+ + GNC +G C +C C C G+F P
Sbjct: 818 RN-GPVRLCRLCQCSDNIDPN-AVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAP 875
Query: 402 ----NCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNC 451
CK C CNL GT + C P G C C + G+ C C+ G+Y+ + C+ C
Sbjct: 876 NPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERC 935
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--PTCKPCNCDTSGTEPSIC 509
+C+ +GS + CD TG C C+ +G+ C +C+ ++ + CKPC+C G+ C
Sbjct: 936 DCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQC 995
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYY 535
D G+C C+ GF G RCDQC Y+
Sbjct: 996 KD-DGRCECREGFVGNRCDQCEENYF 1020
Score = 185 bits (451), Expect = 2e-45
Identities = 108/345 (31%), Positives = 156/345 (45%), Gaps = 39/345 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C G C C Y R C C C+ H T C+ E+G C CR
Sbjct: 692 CPVGYGGQFCEMCLSGYRRET-PNLGPYSPCVLCACNGHSET--CDPETGVCNCRDNTAG 748
Query: 388 PDCSSCAYGYFD------YPNCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICE 440
P C C+ GY+ +C+PC C + + +C C GK CE+C+
Sbjct: 749 PHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 441 DGYYSPE---------CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQAGY 488
DGY+ C+ C+C+ + V C++LTG+C C +G C++C+ G+
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 489 YNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
+ P CK CNC+ GT + S C+ V+GQC C G C C G+Y
Sbjct: 869 FGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQS 928
Query: 540 GRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKY-PD-CLSCNCD 596
G+ C C+C GST+ C G+C C G C++C ++ + P+ C C+C
Sbjct: 929 GQG--CERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCH 986
Query: 597 VSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQ-FYN--YPACEEC 638
GS+ C D+G C C+ F G +CD C E FYN +P C+EC
Sbjct: 987 PEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 176 bits (429), Expect = 1e-42
Identities = 108/343 (31%), Positives = 151/343 (44%), Gaps = 39/343 (11%)
Query: 470 CTCKSKYSGRTCNQCQAGYY----NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
CTC Y G+ C C +GY N PC CD +G C C+ GP
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGP 749
Query: 526 RCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTSTSC--SADGKC-NCLTNFGGAQCDQCS 581
C++C GYY G C PC C P GS+ + + C NC T G +C+ C
Sbjct: 750 HCEKCSDGYYGDSTAGTSSDCQPCPC-PGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808
Query: 582 PGYYKYPD--------CLSCNCDVS---GSIGSTCDDNGLC-HCKSNFDGAKCDTCREQF 629
GY+ P C C C + ++G+ G C C N G CD C++ F
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
Query: 630 YNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL 682
+ P C+ CNC+ G + C V G+ C+C V G+ C C P ++NL
Sbjct: 869 FGNPLAPNPADKCKACNCNLYGTMKQQSSCNPV-TGQ-CECLPHVTGQDCGACDPGFYNL 926
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFG 742
Q GCE+C+C+ G+ N G C+ ++GQC C+ + + C++C + G
Sbjct: 927 QSGQ--GCERCDCHALGSTN--GQCDIRTGQCECQPGITGQHCERCEVNHFGFGPE---G 979
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
C CDC GS+ C K G+C C G RCDQ +YF
Sbjct: 980 CKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQ-CEENYF 1020
Score = 175 bits (426), Expect = 2e-42
Identities = 116/370 (31%), Positives = 158/370 (42%), Gaps = 58/370 (15%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS-CEPCNCHNHTTECTYDPEIDEKRLS 312
C C G C C SG+ ++ + N +S C C C+ H+ C DPE
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRE----TPNLGPYSPCVLCACNGHSETC--DPET------ 737
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
G C NC+ NT G +C KC YY D CQPC C S
Sbjct: 738 ----------GVC-NCRDNTAGPHCEKCSDGYYGD-STAGTSSD-CQPCPCPGGSSCAVV 784
Query: 373 EE--ESGRCECRPEFQPPDCSSCAYGYFDYPN--------CKPCTC--NLNGTEGEHCTP 420
+ E C C C GYF P C+ C C N++ +C
Sbjct: 785 PKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNR 844
Query: 421 TDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVSYV--CDKLTGD 469
G C C YN AG C+ C+DG++ + +CK C CN G++ C+ +TG
Sbjct: 845 LTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQ 904
Query: 470 CTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPR 526
C C +G+ C C G+YN + C+ C+C G+ CD +GQC C+ G G
Sbjct: 905 CECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQH 964
Query: 527 CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY- 585
C++C ++ G E C PC+C P GS S C DG+C C F G +CDQC Y+
Sbjct: 965 CERCEVNHFG--FGPEG-CKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFY 1021
Query: 586 --KYPDCLSC 593
+P C C
Sbjct: 1022 NRSWPGCQEC 1031
Score = 167 bits (406), Expect = 7e-40
Identities = 109/358 (30%), Positives = 159/358 (44%), Gaps = 52/358 (14%)
Query: 425 CPCKYNYAGKSCEICEDGY---------YSPECKNCECNTVGSVSYVCDKLTGDCTCKSK 475
C C Y G+ CE+C GY YSP C C CN S CD TG C C+
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP-CVLCACN---GHSETCDPETGVCNCRDN 745
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
+G C +C GYY T C+PC C + + C C G G RC+
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 529 QCLSGYYMQVLGRE---RQCVPCNCDPTGSTST--SCS-ADGKC-NCLTNFGGAQCDQCS 581
C GY+ LGR R C C C + +C+ G+C C+ N G CD+C
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCK 865
Query: 582 PGYYKYP-------DCLSCNCDVSGSI--GSTCDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G++ P C +CNC++ G++ S+C+ G C C + G C C FYN
Sbjct: 866 DGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYN 925
Query: 632 YPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
+ CE C+C G T G + G+ C+C+ + G+ C C+ ++ + P
Sbjct: 926 LQSGQGCERCDCHALGST---NGQCDIRTGQ-CECQPGITGQHCERCEVNHFG---FGPE 978
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC+ C+C+ G+L+ C G+C C++ +CDQC + ++ GC EC
Sbjct: 979 GCKPCDCHPEGSLSL--QCK-DDGRCECREGFVGNRCDQCEENYF--YNRSWPGCQEC 1031
Score = 122 bits (294), Expect = 2e-26
Identities = 73/232 (31%), Positives = 111/232 (47%), Gaps = 33/232 (14%)
Query: 548 CNCDPTGSTSTSCSADGK-CNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S D CNC N G C++C P + P +CL C+C+
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 597 -------VSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY---NYPACEECNCDPRGV 645
+ + G C +C+ N DGA C+ CRE F+ N AC C+C P G
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
++ C S C CK V G C+ C+P + +L E GC C+C+ +G+++
Sbjct: 406 LST--QCDSYGR---CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-- 455
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNN 757
CN ++G+CVCK +V C++C GF+ L++++ GCT C C S+ N
Sbjct: 456 -CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 121 bits (291), Expect = 6e-26
Identities = 66/213 (30%), Positives = 95/213 (44%), Gaps = 25/213 (11%)
Query: 451 CECNTVGS--VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP----------TCKPCN 498
C+CN S + DKL C CK G C +C + + P C PC+
Sbjct: 286 CKCNGHASECMKNEFDKLV--CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCD 343
Query: 499 CDTSGTE----PSICDDVS--GQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
C+ E P + G C C+ G C++C ++ LG C C+C
Sbjct: 344 CNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR--LGNNEACSSCHCS 401
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPD--CLSCNCDVSGSIGSTCDDNG 609
P GS ST C + G+C+C G +CD+C PG++ + C C+CD SGSI + G
Sbjct: 402 PVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETG 461
Query: 610 LCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
C CK N +G C+ C+ F+N + C P
Sbjct: 462 RCVCKDNVEGFNCERCKPGFFNLESSNPRGCTP 494
Score = 114 bits (274), Expect = 7e-24
Identities = 68/223 (30%), Positives = 99/223 (44%), Gaps = 26/223 (11%)
Query: 361 CQCDPHFSTGNCEE-ESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCN 409
C+C+ H S E + C C+ DC C + D P C PC CN
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 410 LNGTEGE------HCTPTDGLCP-CKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
E T G C C+ N G CE C + ++ + C +C C+ VGS
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS 405
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQC 516
+S CD G C+CK G C++CQ G+++ C+PC+CD SG+ C+ +G+C
Sbjct: 406 LSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETGRC 463
Query: 517 ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
+CK G C++C G++ R C PC C S T+
Sbjct: 464 VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Score = 93.9 bits (223), Expect = 1e-17
Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 22/185 (11%)
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG---CG 653
D +C+CK N G C+ C F + P C C+C+ R F
Sbjct: 301 DKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS 360
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
+ G C+D G C C+ ++ L N C C+C+ G+L++ C++ G+
Sbjct: 361 TGHGGHCTNCQDNTDGAHCERCRENFFRLG--NNEACSSCHCSPVGSLST--QCDSY-GR 415
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
C CK V +CD+C GF+ L GC C CD GSID C+ TG+C C VEG
Sbjct: 416 CSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE-CNIETGRCVCKDNVEG 471
Query: 774 RRCDQ 778
C++
Sbjct: 472 FNCER 476
Score = 85.8 bits (203), Expect = 3e-15
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + G C +++ S G C C +GST +C+ GQC C+P + G+ C
Sbjct: 910 HVTGQDCGACDPGFYNLQS--GQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCER 967
Query: 1373 CRTGYYGF--PNCRPCHC-PSTAI---CDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C ++GF C+PC C P ++ C D+G C C + G CD+C+ F G
Sbjct: 968 CEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPG 1027
Query: 1427 CDDC 1430
C +C
Sbjct: 1028 CQEC 1031
Score = 66.9 bits (156), Expect = 1e-09
Identities = 70/296 (23%), Positives = 112/296 (37%), Gaps = 29/296 (9%)
Query: 1259 ENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNE 1318
E+F ++K G W+ Y + + T + I E C ISP
Sbjct: 158 ESFA-IYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLT 216
Query: 1319 TG-LCREAMFSITSEYNSGARPCLCDFMGSTELEC-----NTFGGQCPCKPNVIGRTCSA 1372
G + + S YN P L +++ +T++ NTFG + P V+ A
Sbjct: 217 GGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYA 276
Query: 1373 CRTGYYGFPNCRPCHCPSTAICD--DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDD- 1429
G C+ S + + D +C C N G +C++C P+ + +R +
Sbjct: 277 ISDFAVG-GRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAES 335
Query: 1430 -CNCNPLGVVGNQLQCEAD---------SGKCA-CRENVRGRVCDHCVPGHYAFPD---C 1475
C P G +C D G C C++N G C+ C + + C
Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEAC 395
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C+ G+ CD + +C CK V G CD C+ + +L + GC C C
Sbjct: 396 SSCHCSPVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTE---AGCRPCSC 447
Score = 66.9 bits (156), Expect = 1e-09
Identities = 56/227 (24%), Positives = 92/227 (40%), Gaps = 34/227 (14%)
Query: 231 CMCNGHADTC--EPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFS 287
C CNG + C +P + C CQ NT G C +C F +R+ N S
Sbjct: 342 CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENF----FRLGNNEACSS 397
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C + +T+C + G+C +C+ G C++C+P ++
Sbjct: 398 CHCSPVGSLSTQC-------------------DSYGRC-SCKPGVMGDKCDRCQPGFHS- 436
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCT 407
E C+PC CDP S C E+GRC C+ + +C C G+F+ + P
Sbjct: 437 ----LTEAG-CRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRG 491
Query: 408 CNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
C G T+ + Y+ + + +I EDG+ + + E +
Sbjct: 492 CTPCFCFGHSSVCTNAVGYSVYSIS-STFQIDEDGWRAEQRDGSEAS 537
Score = 42.7 bits (96), Expect = 0.024
Identities = 65/267 (24%), Positives = 106/267 (39%), Gaps = 29/267 (10%)
Query: 2101 DSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSD 2160
DS N I + E L + Q K D ++ ++ E KNLL + +D
Sbjct: 1278 DSETLENEANNIKMEAENLEQLIDQ-KLKDYEDLREDMRGKELEVKNLLEKGKTEQQTAD 1336
Query: 2161 KQISRAAKLAEDAERTLAAVRESAREATEVVKHVADL-------ATGLE--LSQQPKVDS 2211
+ ++RA AE R++ +EA +++ ++ D T E L + P ++
Sbjct: 1337 QLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQ 1396
Query: 2212 ALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRP---- 2267
+TEA + + A + L A N + ER+ VQ KA + R
Sbjct: 1397 TITEANEKTRE-AQQALGSAAADATEA-KNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 2268 -DLKFE------SLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNS 2320
DL E L A +ELK K DD + +A + A+E R +K NS
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAK-----NS 1509
Query: 2321 VTKLNTAAMGDLIDAAYDIGNATYNNM 2347
VT L + + DL++ + N +
Sbjct: 1510 VTSL-LSIINDLLEQLGQLDTVDLNKL 1535
>AY481573-1|AAS47698.1| 5202|Homo sapiens Usher syndrome 2A isoform B
protein.
Length = 5202
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 64.5 bits (150), Expect = 7e-09
Identities = 73/325 (22%), Positives = 138/325 (42%), Gaps = 23/325 (7%)
Query: 3336 SFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT----YN 3391
SFRT +G ++F A N ++ A ++ +L+++F+ G +++T+ Y+
Sbjct: 1547 SFRTKVPEGLIVFAASPG---NQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYS 1603
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
D WH + R+ G++ +D G +++ +T + + GGL + K +
Sbjct: 1604 DGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPE 1663
Query: 3451 NFYQPFMGCLKGL-LMNGQQVTRIGNAVNALRCVDNIEDGVYFE---ASNNTHSNYL--K 3504
+ F+GCLK + M + I ++ + I +E AS N + +L
Sbjct: 1664 IIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAG 1723
Query: 3505 LLE----NFKVGDEVSISMEVRPRNTTGLLLSVHGK--KDYMVLELLDSEVVANVENGNG 3558
LE F G IS + R GLLL V+ K D++ +E L S ++ N +
Sbjct: 1724 FLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAME-LKSGILTFRLNTSL 1782
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTHSALYIGG 3618
F L Y C+G W+K+ +G +S +Y+GG
Sbjct: 1783 AFTQVDLLLGLSY-CNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVVNSPVYVGG 1841
Query: 3619 -HERPIHKVRGVHSRRGFTGCVRNI 3642
+ ++ + + +GF GC++++
Sbjct: 1842 IPQELLNSYQHLCLEQGFGGCMKDV 1866
Score = 59.7 bits (138), Expect = 2e-07
Identities = 86/382 (22%), Positives = 160/382 (41%), Gaps = 35/382 (9%)
Query: 2851 RFDGRGYATMAGRGY-LTPQSNQVLLFFRTYAPNGLIYLVGEGGY---FFSLLMQDGRVY 2906
RF G GY + + + FRT P GLI G +F+L ++ GR+Y
Sbjct: 1521 RFIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 2907 LQVS-LGNTEDLIIVGTT-RAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIP 2964
G+ ++ + Y+DGKWH++ A R A +T+D + + + +
Sbjct: 1581 FLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVI 1640
Query: 2965 SLDTMNF-GG--NNKGIL----QVPDRGFDGCMRQIS-INGVN-------LDLSENLESI 3009
+T F GG + IL ++ +GF GC++ + + N LD + E I
Sbjct: 1641 GDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQI 1700
Query: 3010 GMAYGCQFASLVSFNGTDSYL--RFVDV------TSENPQLTLKFKTAKPNGLLFVYVSR 3061
+ Y S N +L F+++ N +++ KF+T + NGLL ++
Sbjct: 1701 NV-YNSWEGCPASLNEGAQFLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNK 1759
Query: 3062 TQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN-TYNDSQWHVLTVTHNTSALKLVVDDF 3120
+ + ++ +L Q+D L +Y + +W+ + + S + V+
Sbjct: 1760 DGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGL 1819
Query: 3121 DYFSTDTAPPPLHILDGVLFIGGVQPGYVVS-GSLGSKVPFTGCIGDATI-NGQVLNLLE 3178
++++ PL +++ +++GG+ + S L + F GC+ D G V+NL
Sbjct: 1820 MKHASESGDQPL-VVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTRGAVVNLAS 1878
Query: 3179 PFSNNSVTFGRCGTTITTGGVN 3200
S+ +V G T VN
Sbjct: 1879 -VSSGAVRVNLDGCLSTDSAVN 1899
>AL513305-1|CAH73621.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 64.5 bits (150), Expect = 7e-09
Identities = 73/325 (22%), Positives = 138/325 (42%), Gaps = 23/325 (7%)
Query: 3336 SFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT----YN 3391
SFRT +G ++F A N ++ A ++ +L+++F+ G +++T+ Y+
Sbjct: 1547 SFRTKVPEGLIVFAASPG---NQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYS 1603
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
D WH + R+ G++ +D G +++ +T + + GGL + K +
Sbjct: 1604 DGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPE 1663
Query: 3451 NFYQPFMGCLKGL-LMNGQQVTRIGNAVNALRCVDNIEDGVYFE---ASNNTHSNYL--K 3504
+ F+GCLK + M + I ++ + I +E AS N + +L
Sbjct: 1664 IIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAG 1723
Query: 3505 LLE----NFKVGDEVSISMEVRPRNTTGLLLSVHGK--KDYMVLELLDSEVVANVENGNG 3558
LE F G IS + R GLLL V+ K D++ +E L S ++ N +
Sbjct: 1724 FLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAME-LKSGILTFRLNTSL 1782
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTHSALYIGG 3618
F L Y C+G W+K+ +G +S +Y+GG
Sbjct: 1783 AFTQVDLLLGLSY-CNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVVNSPVYVGG 1841
Query: 3619 -HERPIHKVRGVHSRRGFTGCVRNI 3642
+ ++ + + +GF GC++++
Sbjct: 1842 IPQELLNSYQHLCLEQGFGGCMKDV 1866
Score = 59.7 bits (138), Expect = 2e-07
Identities = 86/382 (22%), Positives = 160/382 (41%), Gaps = 35/382 (9%)
Query: 2851 RFDGRGYATMAGRGY-LTPQSNQVLLFFRTYAPNGLIYLVGEGGY---FFSLLMQDGRVY 2906
RF G GY + + + FRT P GLI G +F+L ++ GR+Y
Sbjct: 1521 RFIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 2907 LQVS-LGNTEDLIIVGTT-RAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIP 2964
G+ ++ + Y+DGKWH++ A R A +T+D + + + +
Sbjct: 1581 FLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVI 1640
Query: 2965 SLDTMNF-GG--NNKGIL----QVPDRGFDGCMRQIS-INGVN-------LDLSENLESI 3009
+T F GG + IL ++ +GF GC++ + + N LD + E I
Sbjct: 1641 GDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQI 1700
Query: 3010 GMAYGCQFASLVSFNGTDSYL--RFVDV------TSENPQLTLKFKTAKPNGLLFVYVSR 3061
+ Y S N +L F+++ N +++ KF+T + NGLL ++
Sbjct: 1701 NV-YNSWEGCPASLNEGAQFLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNK 1759
Query: 3062 TQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN-TYNDSQWHVLTVTHNTSALKLVVDDF 3120
+ + ++ +L Q+D L +Y + +W+ + + S + V+
Sbjct: 1760 DGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGL 1819
Query: 3121 DYFSTDTAPPPLHILDGVLFIGGVQPGYVVS-GSLGSKVPFTGCIGDATI-NGQVLNLLE 3178
++++ PL +++ +++GG+ + S L + F GC+ D G V+NL
Sbjct: 1820 MKHASESGDQPL-VVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTRGAVVNLAS 1878
Query: 3179 PFSNNSVTFGRCGTTITTGGVN 3200
S+ +V G T VN
Sbjct: 1879 -VSSGAVRVNLDGCLSTDSAVN 1899
>AL445650-4|CAH70621.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 64.5 bits (150), Expect = 7e-09
Identities = 73/325 (22%), Positives = 138/325 (42%), Gaps = 23/325 (7%)
Query: 3336 SFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT----YN 3391
SFRT +G ++F A N ++ A ++ +L+++F+ G +++T+ Y+
Sbjct: 1547 SFRTKVPEGLIVFAASPG---NQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYS 1603
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
D WH + R+ G++ +D G +++ +T + + GGL + K +
Sbjct: 1604 DGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPE 1663
Query: 3451 NFYQPFMGCLKGL-LMNGQQVTRIGNAVNALRCVDNIEDGVYFE---ASNNTHSNYL--K 3504
+ F+GCLK + M + I ++ + I +E AS N + +L
Sbjct: 1664 IIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAG 1723
Query: 3505 LLE----NFKVGDEVSISMEVRPRNTTGLLLSVHGK--KDYMVLELLDSEVVANVENGNG 3558
LE F G IS + R GLLL V+ K D++ +E L S ++ N +
Sbjct: 1724 FLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAME-LKSGILTFRLNTSL 1782
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTHSALYIGG 3618
F L Y C+G W+K+ +G +S +Y+GG
Sbjct: 1783 AFTQVDLLLGLSY-CNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVVNSPVYVGG 1841
Query: 3619 -HERPIHKVRGVHSRRGFTGCVRNI 3642
+ ++ + + +GF GC++++
Sbjct: 1842 IPQELLNSYQHLCLEQGFGGCMKDV 1866
Score = 59.7 bits (138), Expect = 2e-07
Identities = 86/382 (22%), Positives = 160/382 (41%), Gaps = 35/382 (9%)
Query: 2851 RFDGRGYATMAGRGY-LTPQSNQVLLFFRTYAPNGLIYLVGEGGY---FFSLLMQDGRVY 2906
RF G GY + + + FRT P GLI G +F+L ++ GR+Y
Sbjct: 1521 RFIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 2907 LQVS-LGNTEDLIIVGTT-RAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIP 2964
G+ ++ + Y+DGKWH++ A R A +T+D + + + +
Sbjct: 1581 FLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVI 1640
Query: 2965 SLDTMNF-GG--NNKGIL----QVPDRGFDGCMRQIS-INGVN-------LDLSENLESI 3009
+T F GG + IL ++ +GF GC++ + + N LD + E I
Sbjct: 1641 GDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQI 1700
Query: 3010 GMAYGCQFASLVSFNGTDSYL--RFVDV------TSENPQLTLKFKTAKPNGLLFVYVSR 3061
+ Y S N +L F+++ N +++ KF+T + NGLL ++
Sbjct: 1701 NV-YNSWEGCPASLNEGAQFLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNK 1759
Query: 3062 TQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN-TYNDSQWHVLTVTHNTSALKLVVDDF 3120
+ + ++ +L Q+D L +Y + +W+ + + S + V+
Sbjct: 1760 DGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGL 1819
Query: 3121 DYFSTDTAPPPLHILDGVLFIGGVQPGYVVS-GSLGSKVPFTGCIGDATI-NGQVLNLLE 3178
++++ PL +++ +++GG+ + S L + F GC+ D G V+NL
Sbjct: 1820 MKHASESGDQPL-VVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTRGAVVNLAS 1878
Query: 3179 PFSNNSVTFGRCGTTITTGGVN 3200
S+ +V G T VN
Sbjct: 1879 -VSSGAVRVNLDGCLSTDSAVN 1899
>AL445650-3|CAH70620.1| 1546|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 1546
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
>AL358858-2|CAH71588.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 64.5 bits (150), Expect = 7e-09
Identities = 73/325 (22%), Positives = 138/325 (42%), Gaps = 23/325 (7%)
Query: 3336 SFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT----YN 3391
SFRT +G ++F A N ++ A ++ +L+++F+ G +++T+ Y+
Sbjct: 1547 SFRTKVPEGLIVFAASPG---NQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYS 1603
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
D WH + R+ G++ +D G +++ +T + + GGL + K +
Sbjct: 1604 DGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPE 1663
Query: 3451 NFYQPFMGCLKGL-LMNGQQVTRIGNAVNALRCVDNIEDGVYFE---ASNNTHSNYL--K 3504
+ F+GCLK + M + I ++ + I +E AS N + +L
Sbjct: 1664 IIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAG 1723
Query: 3505 LLE----NFKVGDEVSISMEVRPRNTTGLLLSVHGK--KDYMVLELLDSEVVANVENGNG 3558
LE F G IS + R GLLL V+ K D++ +E L S ++ N +
Sbjct: 1724 FLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAME-LKSGILTFRLNTSL 1782
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTHSALYIGG 3618
F L Y C+G W+K+ +G +S +Y+GG
Sbjct: 1783 AFTQVDLLLGLSY-CNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVVNSPVYVGG 1841
Query: 3619 -HERPIHKVRGVHSRRGFTGCVRNI 3642
+ ++ + + +GF GC++++
Sbjct: 1842 IPQELLNSYQHLCLEQGFGGCMKDV 1866
Score = 59.7 bits (138), Expect = 2e-07
Identities = 86/382 (22%), Positives = 160/382 (41%), Gaps = 35/382 (9%)
Query: 2851 RFDGRGYATMAGRGY-LTPQSNQVLLFFRTYAPNGLIYLVGEGGY---FFSLLMQDGRVY 2906
RF G GY + + + FRT P GLI G +F+L ++ GR+Y
Sbjct: 1521 RFIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 2907 LQVS-LGNTEDLIIVGTT-RAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIP 2964
G+ ++ + Y+DGKWH++ A R A +T+D + + + +
Sbjct: 1581 FLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVI 1640
Query: 2965 SLDTMNF-GG--NNKGIL----QVPDRGFDGCMRQIS-INGVN-------LDLSENLESI 3009
+T F GG + IL ++ +GF GC++ + + N LD + E I
Sbjct: 1641 GDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQI 1700
Query: 3010 GMAYGCQFASLVSFNGTDSYL--RFVDV------TSENPQLTLKFKTAKPNGLLFVYVSR 3061
+ Y S N +L F+++ N +++ KF+T + NGLL ++
Sbjct: 1701 NV-YNSWEGCPASLNEGAQFLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNK 1759
Query: 3062 TQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN-TYNDSQWHVLTVTHNTSALKLVVDDF 3120
+ + ++ +L Q+D L +Y + +W+ + + S + V+
Sbjct: 1760 DGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGL 1819
Query: 3121 DYFSTDTAPPPLHILDGVLFIGGVQPGYVVS-GSLGSKVPFTGCIGDATI-NGQVLNLLE 3178
++++ PL +++ +++GG+ + S L + F GC+ D G V+NL
Sbjct: 1820 MKHASESGDQPL-VVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTRGAVVNLAS 1878
Query: 3179 PFSNNSVTFGRCGTTITTGGVN 3200
S+ +V G T VN
Sbjct: 1879 -VSSGAVRVNLDGCLSTDSAVN 1899
>AL358858-1|CAH71587.1| 1546|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 1546
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
>AL358452-1|CAI19189.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 64.5 bits (150), Expect = 7e-09
Identities = 73/325 (22%), Positives = 138/325 (42%), Gaps = 23/325 (7%)
Query: 3336 SFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT----YN 3391
SFRT +G ++F A N ++ A ++ +L+++F+ G +++T+ Y+
Sbjct: 1547 SFRTKVPEGLIVFAASPG---NQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYS 1603
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
D WH + R+ G++ +D G +++ +T + + GGL + K +
Sbjct: 1604 DGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPE 1663
Query: 3451 NFYQPFMGCLKGL-LMNGQQVTRIGNAVNALRCVDNIEDGVYFE---ASNNTHSNYL--K 3504
+ F+GCLK + M + I ++ + I +E AS N + +L
Sbjct: 1664 IIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAG 1723
Query: 3505 LLE----NFKVGDEVSISMEVRPRNTTGLLLSVHGK--KDYMVLELLDSEVVANVENGNG 3558
LE F G IS + R GLLL V+ K D++ +E L S ++ N +
Sbjct: 1724 FLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAME-LKSGILTFRLNTSL 1782
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTHSALYIGG 3618
F L Y C+G W+K+ +G +S +Y+GG
Sbjct: 1783 AFTQVDLLLGLSY-CNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVVNSPVYVGG 1841
Query: 3619 -HERPIHKVRGVHSRRGFTGCVRNI 3642
+ ++ + + +GF GC++++
Sbjct: 1842 IPQELLNSYQHLCLEQGFGGCMKDV 1866
Score = 59.7 bits (138), Expect = 2e-07
Identities = 86/382 (22%), Positives = 160/382 (41%), Gaps = 35/382 (9%)
Query: 2851 RFDGRGYATMAGRGY-LTPQSNQVLLFFRTYAPNGLIYLVGEGGY---FFSLLMQDGRVY 2906
RF G GY + + + FRT P GLI G +F+L ++ GR+Y
Sbjct: 1521 RFIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 2907 LQVS-LGNTEDLIIVGTT-RAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIP 2964
G+ ++ + Y+DGKWH++ A R A +T+D + + + +
Sbjct: 1581 FLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVI 1640
Query: 2965 SLDTMNF-GG--NNKGIL----QVPDRGFDGCMRQIS-INGVN-------LDLSENLESI 3009
+T F GG + IL ++ +GF GC++ + + N LD + E I
Sbjct: 1641 GDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQI 1700
Query: 3010 GMAYGCQFASLVSFNGTDSYL--RFVDV------TSENPQLTLKFKTAKPNGLLFVYVSR 3061
+ Y S N +L F+++ N +++ KF+T + NGLL ++
Sbjct: 1701 NV-YNSWEGCPASLNEGAQFLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNK 1759
Query: 3062 TQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN-TYNDSQWHVLTVTHNTSALKLVVDDF 3120
+ + ++ +L Q+D L +Y + +W+ + + S + V+
Sbjct: 1760 DGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGL 1819
Query: 3121 DYFSTDTAPPPLHILDGVLFIGGVQPGYVVS-GSLGSKVPFTGCIGDATI-NGQVLNLLE 3178
++++ PL +++ +++GG+ + S L + F GC+ D G V+NL
Sbjct: 1820 MKHASESGDQPL-VVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTRGAVVNLAS 1878
Query: 3179 PFSNNSVTFGRCGTTITTGGVN 3200
S+ +V G T VN
Sbjct: 1879 -VSSGAVRVNLDGCLSTDSAVN 1899
>AL139259-1|CAI23041.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 64.5 bits (150), Expect = 7e-09
Identities = 73/325 (22%), Positives = 138/325 (42%), Gaps = 23/325 (7%)
Query: 3336 SFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT----YN 3391
SFRT +G ++F A N ++ A ++ +L+++F+ G +++T+ Y+
Sbjct: 1547 SFRTKVPEGLIVFAASPG---NQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYS 1603
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
D WH + R+ G++ +D G +++ +T + + GGL + K +
Sbjct: 1604 DGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPE 1663
Query: 3451 NFYQPFMGCLKGL-LMNGQQVTRIGNAVNALRCVDNIEDGVYFE---ASNNTHSNYL--K 3504
+ F+GCLK + M + I ++ + I +E AS N + +L
Sbjct: 1664 IIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAG 1723
Query: 3505 LLE----NFKVGDEVSISMEVRPRNTTGLLLSVHGK--KDYMVLELLDSEVVANVENGNG 3558
LE F G IS + R GLLL V+ K D++ +E L S ++ N +
Sbjct: 1724 FLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAME-LKSGILTFRLNTSL 1782
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTHSALYIGG 3618
F L Y C+G W+K+ +G +S +Y+GG
Sbjct: 1783 AFTQVDLLLGLSY-CNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVVNSPVYVGG 1841
Query: 3619 -HERPIHKVRGVHSRRGFTGCVRNI 3642
+ ++ + + +GF GC++++
Sbjct: 1842 IPQELLNSYQHLCLEQGFGGCMKDV 1866
Score = 59.7 bits (138), Expect = 2e-07
Identities = 86/382 (22%), Positives = 160/382 (41%), Gaps = 35/382 (9%)
Query: 2851 RFDGRGYATMAGRGY-LTPQSNQVLLFFRTYAPNGLIYLVGEGGY---FFSLLMQDGRVY 2906
RF G GY + + + FRT P GLI G +F+L ++ GR+Y
Sbjct: 1521 RFIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 2907 LQVS-LGNTEDLIIVGTT-RAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIP 2964
G+ ++ + Y+DGKWH++ A R A +T+D + + + +
Sbjct: 1581 FLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVI 1640
Query: 2965 SLDTMNF-GG--NNKGIL----QVPDRGFDGCMRQIS-INGVN-------LDLSENLESI 3009
+T F GG + IL ++ +GF GC++ + + N LD + E I
Sbjct: 1641 GDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQI 1700
Query: 3010 GMAYGCQFASLVSFNGTDSYL--RFVDV------TSENPQLTLKFKTAKPNGLLFVYVSR 3061
+ Y S N +L F+++ N +++ KF+T + NGLL ++
Sbjct: 1701 NV-YNSWEGCPASLNEGAQFLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNK 1759
Query: 3062 TQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN-TYNDSQWHVLTVTHNTSALKLVVDDF 3120
+ + ++ +L Q+D L +Y + +W+ + + S + V+
Sbjct: 1760 DGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGL 1819
Query: 3121 DYFSTDTAPPPLHILDGVLFIGGVQPGYVVS-GSLGSKVPFTGCIGDATI-NGQVLNLLE 3178
++++ PL +++ +++GG+ + S L + F GC+ D G V+NL
Sbjct: 1820 MKHASESGDQPL-VVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTRGAVVNLAS 1878
Query: 3179 PFSNNSVTFGRCGTTITTGGVN 3200
S+ +V G T VN
Sbjct: 1879 -VSSGAVRVNLDGCLSTDSAVN 1899
>AF091889-1|AAF75819.1| 1546|Homo sapiens Usher syndrome type IIa
protein protein.
Length = 1546
Score = 414 bits (1020), Expect = e-114
Identities = 236/742 (31%), Positives = 365/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE+ +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
>AF055580-1|AAC23748.2| 1546|Homo sapiens Usher syndrome type IIa
protein protein.
Length = 1546
Score = 413 bits (1016), Expect = e-114
Identities = 236/742 (31%), Positives = 364/742 (49%), Gaps = 71/742 (9%)
Query: 46 HPPEYAVD-DRRTWWQSPPLSRGMKYNE-VNLTIDLGQ-EFHVAYVFVKMGNSPRPELWV 102
HP + D D T W S + + N+ V +++DL ++ V Y+ ++ SP+P
Sbjct: 340 HPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQPTEIR 398
Query: 103 LEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIP 162
+++ + ++ WQYF+ ++C FG ++ + K DSV C + S P G +
Sbjct: 399 IQRKKENSLDWEDWQYFA---RNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSRGNVT 453
Query: 163 ISLL----NDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRY 218
S+L N RP N ++N+ LQE +AT +R H + R
Sbjct: 454 FSILTPGPNYRPGYNNFYNTPSLQESVKATQIRFHF--------HGQYYTTETAVNLRHR 505
Query: 219 FYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWR 278
+Y++ +I+I GRC C+GHAD C D +C + T G C++C + K +R
Sbjct: 506 YYAVDEITISGRCQCHGHADNC---DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 279 ISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
F+C+PC C++H+ C Y+ +D G GGG C +C+HNT G NC
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDCEHNTTGRNCE 618
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN----CEEESGRCECRPEFQPPDCSSCA 394
C+ ++R G +DVC+PC CD T N C++ G+C C+ C+ C
Sbjct: 619 LCKDYFFRQVGADPSAIDVCKPCDCDT-VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQ 677
Query: 395 YGYF-----DYPNCKPCTCNLNGT-EGE-HCTPTDGLCPCKYNYAGKSCEICEDG----- 442
G++ D C PC CN +GT +G+ C G C CK N G C+ C G
Sbjct: 678 NGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLR 737
Query: 443 -YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNC 499
+ C+ C+CN GSV+ C+ +G C CK + G C+ C+ +Y + CK C+C
Sbjct: 738 SFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDC 797
Query: 500 DTSGTEP-SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
DT+G+ P ++C+ +GQCICK G +C++CL G + C+PCNCD TG+ +
Sbjct: 798 DTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTING 857
Query: 559 S--CS-ADGKCNCLTNFGGAQCDQCSPGYY-----KYPDCLSCNCDVSGSI-GSTCDD-N 608
S C+ + G+C C G +C+QC P Y + C C CD G++ G+ CD +
Sbjct: 858 SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 609 GLCHCKSNFDGAKCDTCREQFY----NYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
G C C N G +C+ C+ FY N C C+C G C S+ G+ C C+
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHI--CNSL-TGQ-CVCQ 973
Query: 665 D-RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
D + G+ C+ CK Y+ C+ CNC+L+G LN C+ +GQC CKQ V
Sbjct: 974 DASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNE--TCHLVTGQCFCKQFVTGS 1030
Query: 724 QCDQCLDGFYRLQTNDVFGCTE 745
+CD C+ L N++ GC++
Sbjct: 1031 KCDACVPSASHLDVNNLLGCSK 1052
Score = 303 bits (744), Expect = 7e-81
Identities = 176/486 (36%), Positives = 237/486 (48%), Gaps = 58/486 (11%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEF--QPPDCSSCAYGYFDYP--------- 401
DE+ + CQC H + + RC C E + C C Y D P
Sbjct: 510 DEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 402 -NCKPCTCNLNGTEG-----------EHCTPTDGLCP-CKYNYAGKSCEICEDGYY---- 444
NCKPC CN + EH G+C C++N G++CE+C+D ++
Sbjct: 570 FNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVG 629
Query: 445 -SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---- 493
P CK C+C+TVG+ S +CD++ G C CK SGR CNQCQ G+YN
Sbjct: 630 ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 494 -CKPCNCDTSGTEPS--ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
C PCNC+TSGT C SGQC CKA G RCD C G+ + C PC C
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 551 DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYY--KYPDCLSCNCDVSGSI-GSTCD 606
+ GS + C+ G+C C G QCD C +Y +C +C+CD +GS+ G+ C+
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809
Query: 607 -DNGLCHCKSNFDGAKCDTCRE-QFY----NYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G C CK N +G +C+ C E FY N C CNCD G C G+
Sbjct: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK-STGQ- 867
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C CK V G CN C+P +NL N C+ C C+ GTL C+ SGQC+C +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT-ICDPISGQCLCVPNR 926
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH-SRVEGRRCDQP 779
R+C+QC GFY + + GC C C G++++ C+ TGQC C + + G+RCDQ
Sbjct: 927 QGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ- 984
Query: 780 IRAHYF 785
+ HYF
Sbjct: 985 CKDHYF 990
Score = 276 bits (677), Expect = 1e-72
Identities = 163/509 (32%), Positives = 242/509 (47%), Gaps = 65/509 (12%)
Query: 324 KCLNCQHN-TEGINCNKCRPTYYRPYGKRWDELDV--CQPCQCDPH------------FS 368
+CL Q + TEG++C++C P Y ++ D++ C+PCQC+ H F
Sbjct: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594
Query: 369 TGNCEEESGRCE-CRPEFQPPDCSSCAYGYFDY----PN----CKPCTCNLNGTEGEH-- 417
+ G C+ C +C C +F P+ CKPC C+ GT
Sbjct: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-----PE-CKNCECNTVGSVS--YVCDKLTGD 469
C G C CK + +G+ C C++G+Y+ P+ C C CNT G+V C + +G
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 470 CTCKSKYSGRTCNQCQAGY-----YNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
C CK+ G C+ C G+ +N C+PC C+ G+ C+ SGQC CK G
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKG 774
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNFGGAQCDQCSP 582
+CD C +Y + C C+CD GS T C+A G+C C N G QC++C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 583 G--YYKYPD---CLSCNCDVSGSIGST--CDDN-GLCHCKSNFDGAKCDTCREQFYN--- 631
G Y + + CL CNCD +G+I + C+ + G C CK G +C+ C YN
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 632 --YPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ C+ C CD G + G P C C QGR CN C+P ++ + N G
Sbjct: 892 DNFQHCQMCECDSLG---TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C C+C+ G +N + CN+ +GQCVC+ + ++CDQC D ++ C C+C
Sbjct: 948 CLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ-TGRCQPCNC 1004
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G+++ C TGQC C V G +CD
Sbjct: 1005 HLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 204 bits (499), Expect = 4e-51
Identities = 124/368 (33%), Positives = 180/368 (48%), Gaps = 53/368 (14%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSG--------TEPSICDD 511
C+ +S G C++C Y + P CKPC C++ +P +
Sbjct: 538 CSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEH 597
Query: 512 V---SGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQ----CVPCNCDPTGSTSTSCSAD 563
G C C+ G C+ C ++ QV G + C PC+CD G+ + S D
Sbjct: 598 FRGGGGVCDDCEHNTTGRNCELCKDYFFRQV-GADPSAIDVCKPCDCDTVGTRNGSILCD 656
Query: 564 ---GKCNCLTNFGGAQCDQCSPGYYKY----PD-CLSCNCDVSGSIGS--TCDDN-GLCH 612
G+CNC + G QC+QC G+Y PD C CNC+ SG++ TC N G C
Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 613 CKSNFDGAKCDTCREQF-----YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
CK+N G +CD C F +N CE C C+ G F P C+CK
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN----PHSGQCECKKEA 772
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+G C+ C+ ++ L N C+ C+C+ AG+L CN K+GQC+CK +V RQC++
Sbjct: 773 KGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGT-VCNAKTGQCICKPNVEGRQCNK 828
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNN--CDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
CL+G + L+ N+ F C C+CD G+I+ + C+K+TGQC C V G RC+Q Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 786 PTLHQFQY 793
T+ FQ+
Sbjct: 889 LTIDNFQH 896
Score = 177 bits (432), Expect = 5e-43
Identities = 113/363 (31%), Positives = 168/363 (46%), Gaps = 43/363 (11%)
Query: 1738 CPRAYRGLSCEQCAEGHYRL----PSGF--CVPCQCN-----GHSDQCDVNTGICLNCAD 1786
C G +CE C + +R PS C PC C+ S CD G C NC
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKR 666
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
+ G C C +G++ + P C C C + + + D++ + + C C+
Sbjct: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNC-----NTSGTVDGDITCHQNSGQCKCKAN 720
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTA 1906
G RC++C G+ + D+ C+PC C N++ C+ +G C +C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG----CEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCDRCAP 1963
G C+ C FYG + NC AC CD G C++ TG C+C+P V G +C++C
Sbjct: 774 GLQCDTCRENFYGLDV--TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831
Query: 1964 DHWGL--NTGLGCTPCNC---GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
++ L N C PCNC G + S C+ GQC C GVTG +C+QC +N T
Sbjct: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891
Query: 2019 DG---CDHCNCNT-GYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP--QEGCLEC 2071
D C C C++ G G +C+ +GQC C+P G +C++C + + P GCL C
Sbjct: 892 DNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Query: 2072 DSC 2074
SC
Sbjct: 952 -SC 953
Score = 177 bits (430), Expect = 8e-43
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 28/334 (8%)
Query: 1765 CQCNGHSDQCDVNTG--ICLNCADN-TIGDHCEFCMSGYH------GDATVGTPRDCLIC 1815
CQC+GH+D CD + CL ++ T G HC+ C+ Y+ GD +C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF--NCKPC 575
Query: 1816 ACPMPYPSNNFALSCD-----LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
C S ++ +S D G + +C+ G CE C Y+ D
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC-KDYFFRQVGADPSA 634
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTA 1929
D CKPC+C CD I G C C + +G CN C GFY + C+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSP 693
Query: 1930 CICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNCGI-A 1982
C C+ G D C +G C C+ VIG +CD C L + +GC PC C +
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-GFMCNA-TG 2040
S + C+ +GQC C K G QCD C F+ C C+C+T S+ G +CNA TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 2041 QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
QC C P V G +C++C E + Q C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 174 bits (424), Expect = 4e-42
Identities = 119/365 (32%), Positives = 167/365 (45%), Gaps = 49/365 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCN--GHSD---QCDVNTGICLNCA 1785
+C C R G C QC G Y L P G C PC CN G D C N+G C C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQC-KCK 718
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N IG C+ C G+ + C C C + N F C+ +G C C+
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV-GCEPCQCNLHGSVNKF---CN-PHSG---QCECKK 770
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS-CDSINGDCLKCV 1902
G +C+ C +YG+ CK C+C +G++ PG+ C++ G C+ C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGSL----PGTVCNAKTGQCI-CK 818
Query: 1903 NNTAGAACNLCAPG-FYGDAIFSKNCTACICDEFGMAD----CDSTTGTCVCRPGVIGEK 1957
N G CN C G FY S C C CD+ G + C+ +TG C C+ GV G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 1958 CDRCAPDHWGL--NTGLGCTPCNCGIAS--ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C++C P + L + C C C T CD +GQC C G++C+QC GF
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 2014 W--NYTKDGCDHCNCNTGYSVGFMCNA-TGQCECL-PGVIGEKCDRCPERWV-LIPQEG- 2067
+ GC C+C+T +V +CN+ TGQC C + G++CD+C + + PQ G
Sbjct: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998
Query: 2068 CLECD 2072
C C+
Sbjct: 999 CQPCN 1003
Score = 163 bits (397), Expect = 8e-39
Identities = 111/344 (32%), Positives = 154/344 (44%), Gaps = 43/344 (12%)
Query: 1762 CVPCQCNGHSDQCDVNT--------------GICLNCADNTIGDHCEFCMSGYHGD--AT 1805
C PCQCN HS C N G+C +C NT G +CE C + A
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
C C C + N ++ CD + G CNC+ G +C C G+Y + E
Sbjct: 632 PSAIDVCKPCDCD-TVGTRNGSILCD--QIGG--QCNCKRHVSGRQCNQCQNGFYNLQE- 685
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
D C PCNC+ + +C +G C KC N G C+ C GF F+
Sbjct: 686 ---LDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND 741
Query: 1926 -NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIA 1982
C C C+ G + C+ +G C C+ G +CD C + +GL+ C C+C A
Sbjct: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTA 800
Query: 1983 SE--STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG---CDHCNCN-TGYSVG-FM 2035
T C+ GQC C V G+QC++C G + ++ C CNC+ TG G +
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 2036 CN-ATGQCECLPGVIGEKCDRC-PERWVLIPQ--EGC--LECDS 2073
CN +TGQC C GV G +C++C P R+ L + C ECDS
Sbjct: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Score = 161 bits (390), Expect = 6e-38
Identities = 94/284 (33%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSD----QCDVNTGICLNCADNTIG 1790
+C+C + +GL C+ C E Y L C C C+ C+ TG C+ C N G
Sbjct: 765 QCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEG 823
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ G + CL C C N +L C N S C C+ G G
Sbjct: 824 RQCNKCLEG-NFYLRQNNSFLCLPCNCDKTGTING-SLLC----NKSTGQCPCKLGVTGL 877
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
RC C Y + D H C+ C C ++ CD I+G CL CV N G C
Sbjct: 878 RCNQCEPHRYNLTIDNFQH----CQMCECD-SLGTLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCR-PGVIGEKCDRCAPDHWG 1967
N C PGFY + C C C G + C+S TG CVC+ + G++CD+C ++G
Sbjct: 932 NQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 1968 LNTGLG-CTPCNCGIASESTQ-CDDDNGQCRCAKGVTGKQCDQC 2009
+ G C PCNC ++ + C GQC C + VTG +CD C
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 158 bits (383), Expect = 4e-37
Identities = 105/343 (30%), Positives = 145/343 (42%), Gaps = 42/343 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCNGHSDQ---CDVNTGICLNCADNT 1788
+C+C GL C+ C G L S C PCQCN H C+ ++G C C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1789 IGDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
G C+ C ++G D T +C C C + C N C C+P
Sbjct: 773 KGLQCDTCRENFYGLDVT-----NCKACDCDTA--GSLPGTVC----NAKTGQCICKPNV 821
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGS--CDSINGDCLKCVN 1903
G +C C G + + ++ C PCNC +G IN GS C+ G C C
Sbjct: 822 EGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTIN----GSLLCNKSTGQC-PCKL 872
Query: 1904 NTAGAACNLCAPGFYGDAIFS-KNCTACICDEFGMAD---CDSTTGTCVCRPGVIGEKCD 1959
G CN C P Y I + ++C C CD G CD +G C+C P G +C+
Sbjct: 873 GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 1960 RCAPDHW-GLNTGLGCTPCNCGIASESTQ-CDDDNGQCRCAKG-VTGKQCDQCAAGFWNY 2016
+C P + GC PC+C C+ GQC C + G++CDQC ++ +
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 2017 TKDG--CDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRC 2056
C CNC+ ++ C+ TGQC C V G KCD C
Sbjct: 993 DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 149 bits (361), Expect = 2e-34
Identities = 74/222 (33%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 1327 FSITSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNC 1383
F +N G PC C+ GS CN GQC CK G C CR +YG NC
Sbjct: 733 FKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC 792
Query: 1384 RPCHC------PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPL 1435
+ C C P T G CIC NVEG C++C F C CNC+
Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY-----AFPDCYQCTCNRHGT-TYDV 1489
G + L C +G+C C+ V G C+ C P Y F C C C+ GT +
Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD + QC C N +G+ C+ C+ ++ + N GC C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSC 953
Score = 146 bits (353), Expect = 2e-33
Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 21/238 (8%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTC 1370
++S + C+ +++ G PC C+ G+ ++ C+ GQC CK NVIG C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 1371 SACRTGY-----YGFPNCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRCKPYTFN 1420
C G+ + C PC C C+ +G C C K +G CD C+ +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-----C 1475
DV C C+C+ G + + C A +G+C C+ NV GR C+ C+ G++ C
Sbjct: 787 LDV-TNCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 1476 YQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C++ GT +C+++T QC CK V G C+ C+ +NL DN C C C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 141 bits (342), Expect = 4e-32
Identities = 78/216 (36%), Positives = 107/216 (49%), Gaps = 27/216 (12%)
Query: 1338 RPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYGF-----PNCRPCHCPS 1390
+PC CD +G+ + C+ GGQC CK +V GR C+ C+ G+Y C PC+C +
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1391 TAICD-------DNGMCICPKNVEGENCDRCKPYTFNF-----DVQRGCDDCNCNPLGVV 1438
+ D ++G C C NV G CD C + F F DV GC+ C CN G V
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN-FGFKFLRSFNDV--GCEPCQCNLHGSV 755
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--PDCYQCTCNRHGT-TYDVCDQNTA 1495
N+ C SG+C C++ +G CD C Y +C C C+ G+ VC+ T
Sbjct: 756 -NKF-CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 1496 QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
QC CK NV G+ C+ C E F L+ +N C C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 134 bits (324), Expect = 6e-30
Identities = 84/275 (30%), Positives = 125/275 (45%), Gaps = 26/275 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE--LECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
C E F + + PC CD G+ L CN GQCPCK V G C+ C Y
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN 888
Query: 1380 -----FPNCRPCHCPSTA-----ICDD-NGMCICPKNVEGENCDRCKP-YTFNFDVQRGC 1427
F +C+ C C S ICD +G C+C N +G C++C+P + + GC
Sbjct: 889 LTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRE-NVRGRVCDHCVPGHYAFPD----CYQCTCNR 1482
C+C+ G V N + C + +G+C C++ ++ G+ CD C ++ F C C C+
Sbjct: 949 LPCSCHTTGAV-NHI-CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-F----CFGKTTR 1537
G + C T QC+CK V G CD C +L +N GC+K F G+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQS 1066
Query: 1538 CSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHED 1572
S+ +W+ D + L+ + E+Y ED
Sbjct: 1067 SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTED 1101
Score = 134 bits (323), Expect = 8e-30
Identities = 68/199 (34%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 1356 GGQCP-CKPNVIGRTCSACRTGYY--------GFPNCRPCHCPSTA------ICDD-NGM 1399
GG C C+ N GR C C+ ++ C+PC C + +CD G
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1400 CICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV 1457
C C ++V G C++C+ +N GC CNCN G V + C +SG+C C+ NV
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721
Query: 1458 RGRVCDHCVPGHY---AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
G CDHC G +F D C C CN HG+ C+ ++ QC CK +G CDTC+
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCR 781
Query: 1513 EEYFNLQDDNPDGCTKCFC 1531
E ++ L N C C C
Sbjct: 782 ENFYGLDVTN---CKACDC 797
Score = 132 bits (319), Expect = 2e-29
Identities = 84/274 (30%), Positives = 112/274 (40%), Gaps = 27/274 (9%)
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGNINP-- 1885
+CD + C+ + G C+ C Y P D CKPC C+ +
Sbjct: 526 NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCH 585
Query: 1886 ----QDPGSCDSINGD---CLKCVNNTAGAACNLCAPGFY----GDAIFSKNCTACICDE 1934
DP + G C C +NT G C LC F+ D C C CD
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 1935 FGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT--GLGCTPCNC---GIASES 1985
G + CD G C C+ V G +C++C + L GC+PCNC G
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNA-TGQ 2041
C ++GQC+C V G +CD C GF ++ GC+ C CN SV CN +GQ
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
CEC G +CD C E + + C CD T
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Score = 105 bits (252), Expect = 3e-21
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 31/255 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C C G C +C EG++ L S C+PC C+ S C+ +TG C C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKL 872
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C C + + T+ + C +C C CD C C P
Sbjct: 873 GVTGLRCNQC-EPHRYNLTIDNFQHCQMCECDSL--GTLPGTICDPISG----QCLCVPN 925
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNN 1904
G RC C G+Y P + TG C PC+C +G +N C+S+ G C+ +
Sbjct: 926 RQGRRCNQCQPGFYISPGNA---TG--CLPCSCHTTGAVNH----ICNSLTGQCVCQDAS 976
Query: 1905 TAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCA 1962
AG C+ C ++G + C C C G + C TG C C+ V G KCD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 1963 P--DHWGLNTGLGCT 1975
P H +N LGC+
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/194 (30%), Positives = 77/194 (39%), Gaps = 30/194 (15%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLP-SGF--CVPCQCNG----HSDQCDVNTGICLNC 1784
S +C C GL C QC Y L F C C+C+ CD +G CL C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-C 922
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
N G C C G++ + G CL C+C N+ N C CQ
Sbjct: 923 VPNRQGRRCNQCQPGFY--ISPGNATGCLPCSCHTTGAVNHIC-------NSLTGQCVCQ 973
Query: 1845 -PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKC 1901
G RC+ C Y+G D TG C+PCNC SG +N +C + G C C
Sbjct: 974 DASIAGQRCDQCKDHYFGF----DPQTG-RCQPCNCHLSGALNE----TCHLVTGQCF-C 1023
Query: 1902 VNNTAGAACNLCAP 1915
G+ C+ C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
>AB208887-1|BAD92124.1| 1379|Homo sapiens laminin, gamma 3 precursor
variant protein.
Length = 1379
Score = 411 bits (1013), Expect = e-113
Identities = 257/794 (32%), Positives = 361/794 (45%), Gaps = 76/794 (9%)
Query: 1324 EAMFSITSEYNSGARPCLCDFMGSTELECNT-FGGQ--CPCKPNVIGRTCSACRTGYYGF 1380
++ + S+++ G R C C+ S EC GQ C C+ N G C C +
Sbjct: 60 QSYYYAVSDFSVGGR-CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 115
Query: 1381 P----------NCRPCHCPSTAI-CD----------DNGMCI-CPKNVEGENCDRCKPYT 1418
P C PC+C + C G C C + G +C+RC+
Sbjct: 116 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 175
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CY 1476
+++D + C C+C G + LQC+ D+G CAC+ V G CD C+PG ++ + C
Sbjct: 176 YHWDPRMPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 232
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTT 1536
CTCN G+ D CD + +C CK NV G CD C+ FNLQ NP GC+ CFC+G +
Sbjct: 233 PCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 291
Query: 1537 RCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELT-NVTVLTVGLNDGVTNGKV 1595
C+S+ + ++ + + E P+ + N +L+ + +T
Sbjct: 292 VCAST--AQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEELT---- 345
Query: 1596 AYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPP- 1654
AP +LG + SYG L T GD + G L H+S+ P
Sbjct: 346 ----APGKFLGDQRFSYGQPLILTFRVPP-GDSPLPVQLRLEGTGLALSLRHSSLSGPQD 400
Query: 1655 VGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLE 1714
G P ++ +E S P+ F L N++ L +R S S + V
Sbjct: 401 AGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGP-----SPAGPVFL 455
Query: 1715 IGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR-LPSG----FCVPCQCNG 1769
V + A+ VE C CP Y G CE CA G+ R +P G CVPC CN
Sbjct: 456 TEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ 515
Query: 1770 HSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS 1829
H CD NTGIC+ C+ +T G CE C+ G++G+ G DC C CP +
Sbjct: 516 HGT-CDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSAC 567
Query: 1830 CDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPG 1889
+ E+G ++ +C PG G RCE C G++G P H C C CSGN++P G
Sbjct: 568 TTIPESGEVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCSGNVDPNAVG 626
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK---NCTACICDEFGMAD----CDS 1942
+CD ++G CL+C++NT G C C GFYG A+ + C C C G CD
Sbjct: 627 NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDP 686
Query: 1943 TTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
TG C C P V C RC P + L G GC C C + S+ QC GQC C GV
Sbjct: 687 VTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGV 746
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV 2061
TG+ CD+C GF+ ++ GC C C+ + C+ G C C PG G KCDRC + +
Sbjct: 747 TGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 806
Query: 2062 LIPQ-EGCLECDSC 2074
L C +C SC
Sbjct: 807 LTADGTHCQQCPSC 820
Score = 206 bits (504), Expect = 9e-52
Identities = 108/309 (34%), Positives = 148/309 (47%), Gaps = 31/309 (10%)
Query: 153 IVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDP 212
I PL G + S L RPS+ + S LQEW +T + + L R + +DP
Sbjct: 1 ISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF----KDP 56
Query: 213 TVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGF 272
V + Y+Y++ D S+GGRC CNGHA C P D AG L CRCQHNT G C +C F
Sbjct: 57 KVLQSYYYAVSDFSVGGRCKCNGHASECGP-DVAGQL---ACRCQHNTTGTDCERCLPFF 112
Query: 273 EQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNT 332
+ + W C PCNC + ECT+D E+ G GG+C +C+ +T
Sbjct: 113 QDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS------TGH---GGRCHHCRDHT 163
Query: 333 EGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS 392
G +C +C+ +Y WD CQPC C S +++G C C+P C
Sbjct: 164 AGPHCERCQENFY-----HWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDR 218
Query: 393 CAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE--- 447
C G+ C+PCTCN G+ + C P G CPCK N G C+ C G ++ +
Sbjct: 219 CLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHN 277
Query: 448 ---CKNCEC 453
C +C C
Sbjct: 278 PAGCSSCFC 286
Score = 184 bits (449), Expect = 4e-45
Identities = 113/369 (30%), Positives = 164/369 (44%), Gaps = 58/369 (15%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+C C G C C G++++ + Q SC PC C+ H T C DP
Sbjct: 476 ICSCPTGYTGQFCESCAPGYKRE---MPQGGPYASCVPCTCNQHGT-C--DPNT------ 523
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFSTGN 371
G C+ C H+TEG +C +C P +Y P+ + D+ CQPC C P S
Sbjct: 524 ----------GICV-CSHHTEGPSCERCLPGFYGNPFAGQADD---CQPCPC-PGQSACT 568
Query: 372 CEEESGR--C-ECRPEFQPPDCSSCAYGYFDYP--------NCKPCTC--NLNGTEGEHC 418
ESG C C P + C C G+F P C C C N++ +C
Sbjct: 569 TIPESGEVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNC 628
Query: 419 TPTDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVS--YVCDKLT 467
P G C C +N G CE C++G+Y + +C C C+ GSVS CD +T
Sbjct: 629 DPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVT 688
Query: 468 GDCTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
G C+C + R C++C G+++ C+ C C G++ C +GQC C+ G G
Sbjct: 689 GQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTG 748
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
CD+C G++ + + C C C P G+ S C +G C C F G +CD+C +
Sbjct: 749 QACDRCQLGFFGFSI---KGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNF 805
Query: 585 YKYPDCLSC 593
+ D C
Sbjct: 806 FLTADGTHC 814
Score = 182 bits (444), Expect = 2e-44
Identities = 107/350 (30%), Positives = 152/350 (43%), Gaps = 48/350 (13%)
Query: 327 NCQHNTEGINCNKCRPTYYR--PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPE 384
+C G C C P Y R P G + C PC C+ H G C+ +G C C
Sbjct: 478 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCNQH---GTCDPNTGICVCSHH 531
Query: 385 FQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGEHCTPTDG--LCP-CKYNYAGKS 435
+ P C C G++ P +C+PC C G P G +C C G+
Sbjct: 532 TEGPSCERCLPGFYGNPFAGQADDCQPCPCP--GQSACTTIPESGEVVCTHCPPGQRGRR 589
Query: 436 CEICEDGYYS--------PE-CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQ 483
CE+C+DG++ P+ C C+C+ + V CD L+G C C +G C
Sbjct: 590 CEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 649
Query: 484 CQAGYYNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGY 534
CQ G+Y C PC+C G+ E CD V+GQC C C +C G+
Sbjct: 650 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 709
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYP--DCL 591
+ GR C C C P GS C G+C C G CD+C G++ + C
Sbjct: 710 FDLQPGRG--CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCR 767
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY---NYPACEEC 638
+C C G+ + C +NG C C+ F+G KCD C + F+ + C++C
Sbjct: 768 ACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 817
Score = 171 bits (417), Expect = 3e-41
Identities = 108/339 (31%), Positives = 153/339 (45%), Gaps = 45/339 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C+C + Y+G+ C C GY Y +C PC C+ GT CD +G C+C
Sbjct: 477 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 532
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNCDPTGSTSTSCSADGK--C-NCLTNFGGAQCD 578
GP C++CL G+Y G+ C PC C P S T+ G+ C +C G +C+
Sbjct: 533 EGPSCERCLPGFYGNPFAGQADDCQPCPC-PGQSACTTIPESGEVVCTHCPPGQRGRRCE 591
Query: 579 QCSPGYYKYP--------DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCR 626
C G++ P C C C +V + CD +G C C N G C+ C+
Sbjct: 592 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 651
Query: 627 EQFYNY-----PA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
E FY PA C C+C P+G + C V G+ C C V R C+ C P +
Sbjct: 652 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV-TGQ-CSCLPHVTARDCSRCYPGF 709
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
++LQ GC C C+ G+ C+ K+GQC C+ V + CD+C GF+
Sbjct: 710 FDLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFFGF---S 762
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
+ GC C C G+ C + G C C EG +CD+
Sbjct: 763 IKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDR 800
Score = 170 bits (414), Expect = 7e-41
Identities = 107/352 (30%), Positives = 152/352 (43%), Gaps = 48/352 (13%)
Query: 379 CECRPEFQPPDCSSCAYGY-------FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
C C + C SCA GY Y +C PCTCN +GT C P G+C C ++
Sbjct: 477 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 532
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQ 483
G SCE C G+Y + +C+ C C + + + + CT C GR C
Sbjct: 533 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESGEVVCTHCPPGQRGRRCEV 592
Query: 484 CQAGYYNYPT-----CKPCN-CDTSG-TEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
C G++ P +PC+ C SG +P+ CD +SG C+ C G C+ C
Sbjct: 593 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 652
Query: 533 GYYMQVLGRE--RQCVPCNCDPTGSTSTSCSAD---GKCNCLTNFGGAQCDQCSPGYYKY 587
G+Y L +C+PC+C P GS S D G+C+CL + C +C PG++
Sbjct: 653 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDL 712
Query: 588 P---DCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQFYNY--PACEECNCD 641
C SC C GS C G C C+ G CD C+ F+ + C C C
Sbjct: 713 QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCS 772
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
P G A+ A C C C+ +G C+ C ++ + C+QC
Sbjct: 773 PLG--AASAQCHE---NGTCVCRPGFEGYKCDRCHDNFFLTADGT--HCQQC 817
Score = 167 bits (406), Expect = 7e-40
Identities = 96/339 (28%), Positives = 146/339 (43%), Gaps = 50/339 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H TC+P N +C C H+T GP C +C GF + + C+P
Sbjct: 511 CTCNQHG-TCDP-------NTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQP 558
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + CT PE G C +C G C C ++
Sbjct: 559 CPCPGQSA-CTTIPE--------------SGEVVCTHCPPGQRGRRCEVCDDGFFGDPLG 603
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP---- 401
+ C CQC DP+ + GNC+ SG C C C C G++
Sbjct: 604 LFGHPQPCHQCQCSGNVDPN-AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR 662
Query: 402 ---NCKPCTCNLNGTEGEH--CTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCE 452
C PC+C+ G+ E C P G C C + + C C G++ + C++C+
Sbjct: 663 PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCK 722
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICD 510
C+ +GS C TG CTC+ +G+ C++CQ G++ + C+ C C G + C
Sbjct: 723 CHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH 782
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRE-RQCVPC 548
+ +G C+C+ GF G +CD+C +++ G +QC C
Sbjct: 783 E-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 820
Score = 145 bits (352), Expect = 2e-33
Identities = 100/358 (27%), Positives = 145/358 (40%), Gaps = 51/358 (14%)
Query: 424 LCPCKYNYAGKSCEICEDGYYS--PE------CKNCECNTVGSVSYVCDKLTGDCTCKSK 475
+C C Y G+ CE C GY P+ C C CN G+ CD TG C C
Sbjct: 476 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHH 531
Query: 476 YSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
G +C +C G+Y P C+PC C +I + C C G G RC+
Sbjct: 532 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESGEVVCTHCPPGQRGRRCE 591
Query: 529 QCLSGYY---MQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCS 581
C G++ + + G + C C C + + D G C CL N G C+ C
Sbjct: 592 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 651
Query: 582 PGYY-------KYPDCLSCNCDVSGSIGST--CDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G+Y C+ C+C GS+ CD G C C + C C F++
Sbjct: 652 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 711
Query: 632 YP---ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
C C C P G C P C C+ V G+ C+ C+ ++ ++
Sbjct: 712 LQPGRGCRSCKCHPLGSQED--QCH--PKTGQCTCRPGVTGQACDRCQLGFFG---FSIK 764
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC C C+ G ++ C+ ++G CVC+ +CD+C D F+ T D C +C
Sbjct: 765 GCRACRCSPLGAASA--QCH-ENGTCVCRPGFEGYKCDRCHDNFF--LTADGTHCQQC 817
Score = 129 bits (312), Expect = 2e-28
Identities = 70/217 (32%), Positives = 99/217 (45%), Gaps = 25/217 (11%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGR-----ERQCVPCNCD 551
C +G DV+GQ C C+ G C++CL + + R +C+PCNC
Sbjct: 75 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 134
Query: 552 PTGSTST-------SCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGS 600
T S G+C+ C + G C++C +Y + C C+C +GS
Sbjct: 135 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGS 194
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRGVTASFAGCGSVPAG 658
+ CDD G C CK G KCD C F++ C C C+P G S C P
Sbjct: 195 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG---SLDTCD--PRS 249
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C CK+ V+G +C+ C+P +NLQ +NP GC C C
Sbjct: 250 GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 286
Score = 121 bits (291), Expect = 6e-26
Identities = 65/201 (32%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSACRTGYYGFP-------NCRPCHC-PSTAI-----CDD- 1396
C+ G C C N G C C+ G+YG C PC C P ++ CD
Sbjct: 628 CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV 687
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
G C C +V +C RC P F+ RGC C C+PLG + QC +G+C CR
Sbjct: 688 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG--SQEDQCHPKTGQCTCRPG 745
Query: 1457 VRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
V G+ CD C G + F C C C+ G C +N C C+ G CD C +
Sbjct: 746 VTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-GTCVCRPGFEGYKCDRCHDN 804
Query: 1515 YFNLQD-DNPDGCTKCFCFGK 1534
+F D + C C+ K
Sbjct: 805 FFLTADGTHCQQCPSCYALVK 825
Score = 113 bits (273), Expect = 9e-24
Identities = 68/227 (29%), Positives = 94/227 (41%), Gaps = 34/227 (14%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P++ G CQHNT G +C +C P + RP+
Sbjct: 75 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERCLPFFQDRPWA 118
Query: 350 KRWDEL-DVCQPCQCDPHFSTGNCEEE-------SGRCE-CRPEFQPPDCSSCAYGYFDY 400
+ E C PC C + E GRC CR P C C ++ +
Sbjct: 119 RGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW 178
Query: 401 -PN--CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE---CKNCECN 454
P C+PC C G+ C T G C CK G C+ C G++S C+ C CN
Sbjct: 179 DPRMPCQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN 237
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
GS+ CD +G C CK G C++C+ G +N P C +
Sbjct: 238 PAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 283
Score = 110 bits (264), Expect = 1e-22
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 33/223 (14%)
Query: 548 CNCDPTGST-STSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S + C C N G C++C P + P +CL CNC
Sbjct: 75 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 134
Query: 597 -------VSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGV 645
+ + G CH C+ + G C+ C+E FY++ C+ C+C G
Sbjct: 135 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAG- 193
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
+ C C CK V G C+ C P + +L E GC C CN AG+L++
Sbjct: 194 -SLHLQCDDTGT---CACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-- 244
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C+ +SG+C CK++V CD+C G + LQ ++ GC+ C C
Sbjct: 245 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 286
Score = 108 bits (259), Expect = 4e-22
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 30/257 (11%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC----EDG 442
P S Y D+ C CN + +E C C++N G CE C +D
Sbjct: 56 PKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 115
Query: 443 YYSP-------ECKNCECN------TVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGY 488
++ EC C C+ T + G C C+ +G C +CQ +
Sbjct: 116 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 175
Query: 489 YNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
Y++ C+PC+C ++G+ CDD +G C CK G +CD+CL G++ E C
Sbjct: 176 YHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSL---SEGGC 231
Query: 546 VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDVSGS 600
PC C+P GS T G+C C N G CD+C PG + C SC C
Sbjct: 232 RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 291
Query: 601 IGSTCDDNGLCHCKSNF 617
+ ++ + H S+F
Sbjct: 292 VCASTAQFQVHHILSDF 308
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 593 CNCDVSGS-IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C C+ S G C C+ N G C+ C F + P C CNC
Sbjct: 75 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 134
Query: 642 PRGVTASFAG--CGSVPAGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA 698
R +F S G C C+D G C C+ +++ P C+ C+C A
Sbjct: 135 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSA 192
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
G+L+ C+ +G C CK V +CD+CL GF+ L GC C C+ GS+D C
Sbjct: 193 GSLHL--QCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-C 245
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D +G+C C VEG CD+
Sbjct: 246 DPRSGRCPCKENVEGNLCDR 265
Score = 89.0 bits (211), Expect = 3e-16
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + C F + + G R C C +GS E +C+ GQC C+P V G+ C
Sbjct: 696 HVTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 753
Query: 1373 CRTGYYGF--PNCRPCHC----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C+ G++GF CR C C ++A C +NG C+C EG CDRC F
Sbjct: 754 CQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTH 813
Query: 1427 CDDC 1430
C C
Sbjct: 814 CQQC 817
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLY-WNLQEYNPF-GCEQCNCNLAGTLNSLGACNTKSGQCVC 716
E+C C G+ C C P Y + + P+ C C CN GT C+ +G CVC
Sbjct: 475 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 528
Query: 717 KQHVGERQCDQCLDGFY-RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGR 774
H C++CL GFY C C C + + C HC GR
Sbjct: 529 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESGEVVCTHCPPGQRGR 588
Query: 775 RCD 777
RC+
Sbjct: 589 RCE 591
Score = 56.0 bits (129), Expect = 2e-06
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 1316 PNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
P TG C + S G RPC C+ GS + C+ G+CPCK NV G C CR
Sbjct: 209 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 267
Query: 1375 TGYYGFPNCRPCHCPSTAICDDNGMC 1400
G + P C S + +C
Sbjct: 268 PGTFNLQPHNPAGCSSCFCYGHSKVC 293
Score = 39.1 bits (87), Expect = 0.30
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Query: 714 CVCKQHVGERQCDQCLDGFYRL--QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRV 771
C C + C+ C G+ R Q C C C+ G+ CD TG C C
Sbjct: 477 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 532
Query: 772 EGRRCDQPIRAHY 784
EG C++ + Y
Sbjct: 533 EGPSCERCLPGFY 545
>AL583807-2|CAH69983.1| 1587|Homo sapiens laminin, gamma 3 protein.
Length = 1587
Score = 411 bits (1012), Expect = e-113
Identities = 257/794 (32%), Positives = 361/794 (45%), Gaps = 76/794 (9%)
Query: 1324 EAMFSITSEYNSGARPCLCDFMGSTELECNT-FGGQ--CPCKPNVIGRTCSACRTGYYGF 1380
++ + S+++ G R C C+ S EC GQ C C+ N G C C +
Sbjct: 256 QSYYYAVSDFSVGGR-CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 1381 P----------NCRPCHCPSTAI-CD----------DNGMCI-CPKNVEGENCDRCKPYT 1418
P C PC+C + C G C C + G +C+RC+
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CY 1476
+++D + C C+C G + LQC+ D+G CAC+ V G CD C+PG ++ + C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 428
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTT 1536
CTCN G+ D CD + +C CK NV G CD C+ FNLQ NP GC+ CFC+G +
Sbjct: 429 PCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 487
Query: 1537 RCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELT-NVTVLTVGLNDGVTNGKV 1595
C+S+ + ++ + + E P+ + N +L+ + +T
Sbjct: 488 VCAST--AQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEELT---- 541
Query: 1596 AYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPP- 1654
APE +LG + SYG L T GD + G L H+S+ P
Sbjct: 542 ----APEKFLGDQRFSYGQPLILTFRVPP-GDSPLPVQLRLEGTGLALSLRHSSLSGPQD 596
Query: 1655 VGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLE 1714
G P ++ +E S P+ F L N++ L +R S S + V
Sbjct: 597 AGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGP-----SPAGPVFL 651
Query: 1715 IGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR-LPSG----FCVPCQCNG 1769
V + A+ VE C CP Y G CE CA G+ R +P G CVPC CN
Sbjct: 652 TEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ 711
Query: 1770 HSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS 1829
H CD NTGIC+ C+ +T G CE C+ G++G+ G DC C CP +
Sbjct: 712 HGT-CDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSAC 763
Query: 1830 CDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPG 1889
+ E+ ++ +C PG G RCE C G++G P H C C CSGN++P G
Sbjct: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCSGNVDPNAVG 822
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK---NCTACICDEFGMAD----CDS 1942
+CD ++G CL+C++NT G C C GFYG A+ + C C C G CD
Sbjct: 823 NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDP 882
Query: 1943 TTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
TG C C P V C RC P + L G GC C C + S+ QC GQC C GV
Sbjct: 883 VTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGV 942
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV 2061
TG+ CD+C GF+ ++ GC C C+ + C+ G C C PG G KCDRC + +
Sbjct: 943 TGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1002
Query: 2062 LIPQ-EGCLECDSC 2074
L C +C SC
Sbjct: 1003 LTADGTHCQQCPSC 1016
Score = 275 bits (675), Expect = 2e-72
Identities = 148/436 (33%), Positives = 218/436 (50%), Gaps = 43/436 (9%)
Query: 34 CDICDANNEAKKHPPEYAVD----DRRTWWQSPPLSRGMKY-NEVNLTIDLGQEFHVAYV 88
C CDA + + H Y D D TWWQSP ++ G++Y VN+T+ LG+ + + YV
Sbjct: 74 CQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYV 133
Query: 89 FVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVI 145
+K S RPE + + K + ++P+Q++S S C++ +G+ + L+P +
Sbjct: 134 RLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQKTYGRPEGQYLRPGEDERVAF 189
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C++E+S I PL G + S L RPS+ + S LQEW +T + + L R +
Sbjct: 190 CTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF 249
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
+DP V + Y+Y++ D S+GGRC CNGHA C P D AG L CRCQHNT G C
Sbjct: 250 ----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGP-DVAGQL---ACRCQHNTTGTDC 301
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
+C F+ + W C PCNC + ECT+D E+ G GG+C
Sbjct: 302 ERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS------TGH---GGRC 352
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
+C+ +T G +C +C+ +Y WD CQPC C S +++G C C+P
Sbjct: 353 HHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTV 407
Query: 386 QPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PCTCN G+ + C P G CPCK N G C+ C G
Sbjct: 408 TGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGT 466
Query: 444 YSPE------CKNCEC 453
++ + C +C C
Sbjct: 467 FNLQPHNPAGCSSCFC 482
Score = 181 bits (441), Expect = 4e-44
Identities = 109/368 (29%), Positives = 161/368 (43%), Gaps = 56/368 (15%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+C C G C C G++++ + Q SC PC C+ H T C DP
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKRE---MPQGGPYASCVPCTCNQHGT-C--DPNT------ 719
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFSTGN 371
G C+ C H+TEG +C +C P +Y P+ + D+ CQPC C +
Sbjct: 720 ----------GICV-CSHHTEGPSCERCLPGFYGNPFAGQADD---CQPCPCPGQSACTT 765
Query: 372 CEE--ESGRCECRPEFQPPDCSSCAYGYFDYP--------NCKPCTC--NLNGTEGEHCT 419
E E C P + C C G+F P C C C N++ +C
Sbjct: 766 IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCD 825
Query: 420 PTDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVS--YVCDKLTG 468
P G C C +N G CE C++G+Y + +C C C+ GSVS CD +TG
Sbjct: 826 PLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 885
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C+C + R C++C G+++ C+ C C G++ C +GQC C+ G G
Sbjct: 886 QCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQ 945
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
CD+C G++ + + C C C P G+ S C +G C C F G +CD+C ++
Sbjct: 946 ACDRCQLGFFGFSI---KGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1002
Query: 586 KYPDCLSC 593
D C
Sbjct: 1003 LTADGTHC 1010
Score = 181 bits (440), Expect = 5e-44
Identities = 104/348 (29%), Positives = 150/348 (43%), Gaps = 44/348 (12%)
Query: 327 NCQHNTEGINCNKCRPTYYR--PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPE 384
+C G C C P Y R P G + C PC C+ H G C+ +G C C
Sbjct: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCNQH---GTCDPNTGICVCSHH 727
Query: 385 FQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCE 437
+ P C C G++ P +C+PC C + +C C G+ CE
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 438 ICEDGYYS--------PE-CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQ 485
+C+DG++ P+ C C+C+ + V CD L+G C C +G C CQ
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Query: 486 AGYYNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYM 536
G+Y C PC+C G+ E CD V+GQC C C +C G++
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYP--DCLSC 593
GR C C C P GS C G+C C G CD+C G++ + C +C
Sbjct: 908 LQPGRG--CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRAC 965
Query: 594 NCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY---NYPACEEC 638
C G+ + C +NG C C+ F+G KCD C + F+ + C++C
Sbjct: 966 RCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 171 bits (416), Expect = 4e-41
Identities = 107/352 (30%), Positives = 152/352 (43%), Gaps = 48/352 (13%)
Query: 379 CECRPEFQPPDCSSCAYGY-------FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
C C + C SCA GY Y +C PCTCN +GT C P G+C C ++
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQ 483
G SCE C G+Y + +C+ C C + + + + CT C GR C
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
Query: 484 CQAGYYNYPT-----CKPCN-CDTSG-TEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
C G++ P +PC+ C SG +P+ CD +SG C+ C G C+ C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 848
Query: 533 GYYMQVLGRE--RQCVPCNCDPTGSTSTSCSAD---GKCNCLTNFGGAQCDQCSPGYYKY 587
G+Y L +C+PC+C P GS S D G+C+CL + C +C PG++
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDL 908
Query: 588 P---DCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQFYNY--PACEECNCD 641
C SC C GS C G C C+ G CD C+ F+ + C C C
Sbjct: 909 QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCS 968
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
P G A+ A C C C+ +G C+ C ++ + C+QC
Sbjct: 969 PLG--AASAQCHE---NGTCVCRPGFEGYKCDRCHDNFFLTADGT--HCQQC 1013
Score = 169 bits (412), Expect = 1e-40
Identities = 106/338 (31%), Positives = 152/338 (44%), Gaps = 43/338 (12%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C+C + Y+G+ C C GY Y +C PC C+ GT CD +G C+C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNCD-PTGSTSTSCSADGKC-NCLTNFGGAQCDQ 579
GP C++CL G+Y G+ C PC C + T+ S + C +C G +C+
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
Query: 580 CSPGYYKYP--------DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCRE 627
C G++ P C C C +V + CD +G C C N G C+ C+E
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 848
Query: 628 QFYNY-----PA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYW 680
FY PA C C+C P+G + C V G+ C C V R C+ C P ++
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV-TGQ-CSCLPHVTARDCSRCYPGFF 906
Query: 681 NLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDV 740
+LQ GC C C+ G+ C+ K+GQC C+ V + CD+C GF+ +
Sbjct: 907 DLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFFGF---SI 959
Query: 741 FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
GC C C G+ C + G C C EG +CD+
Sbjct: 960 KGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDR 996
Score = 166 bits (404), Expect = 1e-39
Identities = 96/339 (28%), Positives = 146/339 (43%), Gaps = 50/339 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H TC+P N +C C H+T GP C +C GF + + C+P
Sbjct: 707 CTCNQHG-TCDP-------NTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQP 754
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + CT PE E C +C G C C ++
Sbjct: 755 CPCPGQSA-CTTIPESREV--------------VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP---- 401
+ C CQC DP+ + GNC+ SG C C C C G++
Sbjct: 800 LFGHPQPCHQCQCSGNVDPN-AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR 858
Query: 402 ---NCKPCTCNLNGTEGEH--CTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCE 452
C PC+C+ G+ E C P G C C + + C C G++ + C++C+
Sbjct: 859 PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCK 918
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICD 510
C+ +GS C TG CTC+ +G+ C++CQ G++ + C+ C C G + C
Sbjct: 919 CHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH 978
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRE-RQCVPC 548
+ +G C+C+ GF G +CD+C +++ G +QC C
Sbjct: 979 E-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 1016
Score = 145 bits (352), Expect = 2e-33
Identities = 100/358 (27%), Positives = 145/358 (40%), Gaps = 51/358 (14%)
Query: 424 LCPCKYNYAGKSCEICEDGYYS--PE------CKNCECNTVGSVSYVCDKLTGDCTCKSK 475
+C C Y G+ CE C GY P+ C C CN G+ CD TG C C
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHH 727
Query: 476 YSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
G +C +C G+Y P C+PC C +I + C C G G RC+
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 529 QCLSGYY---MQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCS 581
C G++ + + G + C C C + + D G C CL N G C+ C
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Query: 582 PGYY-------KYPDCLSCNCDVSGSIGST--CDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G+Y C+ C+C GS+ CD G C C + C C F++
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
Query: 632 YP---ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
C C C P G C P C C+ V G+ C+ C+ ++ ++
Sbjct: 908 LQPGRGCRSCKCHPLGSQED--QCH--PKTGQCTCRPGVTGQACDRCQLGFFG---FSIK 960
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC C C+ G ++ C+ ++G CVC+ +CD+C D F+ T D C +C
Sbjct: 961 GCRACRCSPLGAASA--QCH-ENGTCVCRPGFEGYKCDRCHDNFF--LTADGTHCQQC 1013
Score = 129 bits (312), Expect = 2e-28
Identities = 70/217 (32%), Positives = 99/217 (45%), Gaps = 25/217 (11%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGR-----ERQCVPCNCD 551
C +G DV+GQ C C+ G C++CL + + R +C+PCNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 552 PTGSTST-------SCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGS 600
T S G+C+ C + G C++C +Y + C C+C +GS
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGS 390
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRGVTASFAGCGSVPAG 658
+ CDD G C CK G KCD C F++ C C C+P G S C P
Sbjct: 391 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG---SLDTCD--PRS 445
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C CK+ V+G +C+ C+P +NLQ +NP GC C C
Sbjct: 446 GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 121 bits (291), Expect = 6e-26
Identities = 65/201 (32%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSACRTGYYGFP-------NCRPCHC-PSTAI-----CDD- 1396
C+ G C C N G C C+ G+YG C PC C P ++ CD
Sbjct: 824 CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV 883
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
G C C +V +C RC P F+ RGC C C+PLG + QC +G+C CR
Sbjct: 884 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG--SQEDQCHPKTGQCTCRPG 941
Query: 1457 VRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
V G+ CD C G + F C C C+ G C +N C C+ G CD C +
Sbjct: 942 VTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-GTCVCRPGFEGYKCDRCHDN 1000
Query: 1515 YFNLQD-DNPDGCTKCFCFGK 1534
+F D + C C+ K
Sbjct: 1001 FFLTADGTHCQQCPSCYALVK 1021
Score = 113 bits (273), Expect = 9e-24
Identities = 68/227 (29%), Positives = 94/227 (41%), Gaps = 34/227 (14%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P++ G CQHNT G +C +C P + RP+
Sbjct: 271 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERCLPFFQDRPWA 314
Query: 350 KRWDEL-DVCQPCQCDPHFSTGNCEEE-------SGRCE-CRPEFQPPDCSSCAYGYFDY 400
+ E C PC C + E GRC CR P C C ++ +
Sbjct: 315 RGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW 374
Query: 401 -PN--CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE---CKNCECN 454
P C+PC C G+ C T G C CK G C+ C G++S C+ C CN
Sbjct: 375 DPRMPCQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN 433
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
GS+ CD +G C CK G C++C+ G +N P C +
Sbjct: 434 PAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
Score = 110 bits (264), Expect = 1e-22
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 33/223 (14%)
Query: 548 CNCDPTGST-STSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S + C C N G C++C P + P +CL CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 597 -------VSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGV 645
+ + G CH C+ + G C+ C+E FY++ C+ C+C G
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAG- 389
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
+ C C CK V G C+ C P + +L E GC C CN AG+L++
Sbjct: 390 -SLHLQCDDTGT---CACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-- 440
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C+ +SG+C CK++V CD+C G + LQ ++ GC+ C C
Sbjct: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 108 bits (259), Expect = 4e-22
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 30/257 (11%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC----EDG 442
P S Y D+ C CN + +E C C++N G CE C +D
Sbjct: 252 PKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 443 YYSP-------ECKNCECN------TVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGY 488
++ EC C C+ T + G C C+ +G C +CQ +
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 489 YNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
Y++ C+PC+C ++G+ CDD +G C CK G +CD+CL G++ E C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSL---SEGGC 427
Query: 546 VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDVSGS 600
PC C+P GS T G+C C N G CD+C PG + C SC C
Sbjct: 428 RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 487
Query: 601 IGSTCDDNGLCHCKSNF 617
+ ++ + H S+F
Sbjct: 488 VCASTAQFQVHHILSDF 504
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 593 CNCDVSGS-IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C C+ S G C C+ N G C+ C F + P C CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 642 PRGVTASFAG--CGSVPAGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA 698
R +F S G C C+D G C C+ +++ P C+ C+C A
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSA 388
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
G+L+ C+ +G C CK V +CD+CL GF+ L GC C C+ GS+D C
Sbjct: 389 GSLHL--QCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-C 441
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D +G+C C VEG CD+
Sbjct: 442 DPRSGRCPCKENVEGNLCDR 461
Score = 89.0 bits (211), Expect = 3e-16
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + C F + + G R C C +GS E +C+ GQC C+P V G+ C
Sbjct: 892 HVTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 949
Query: 1373 CRTGYYGF--PNCRPCHC----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C+ G++GF CR C C ++A C +NG C+C EG CDRC F
Sbjct: 950 CQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTH 1009
Query: 1427 CDDC 1430
C C
Sbjct: 1010 CQQC 1013
Score = 65.7 bits (153), Expect = 3e-09
Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLY-WNLQEYNPF-GCEQCNCNLAGTLNSLGACNTKSGQCVC 716
E+C C G+ C C P Y + + P+ C C CN GT C+ +G CVC
Sbjct: 671 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 724
Query: 717 KQHVGERQCDQCLDGFY-RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGR 774
H C++CL GFY C C C + + C HC GR
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 784
Query: 775 RCD 777
RC+
Sbjct: 785 RCE 787
Score = 56.0 bits (129), Expect = 2e-06
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 1316 PNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
P TG C + S G RPC C+ GS + C+ G+CPCK NV G C CR
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
Query: 1375 TGYYGFPNCRPCHCPSTAICDDNGMC 1400
G + P C S + +C
Sbjct: 464 PGTFNLQPHNPAGCSSCFCYGHSKVC 489
Score = 39.1 bits (87), Expect = 0.30
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Query: 714 CVCKQHVGERQCDQCLDGFYRL--QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRV 771
C C + C+ C G+ R Q C C C+ G+ CD TG C C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 772 EGRRCDQPIRAHY 784
EG C++ + Y
Sbjct: 729 EGPSCERCLPGFY 741
>AL583807-1|CAH69984.2| 1619|Homo sapiens laminin, gamma 3 protein.
Length = 1619
Score = 411 bits (1012), Expect = e-113
Identities = 257/794 (32%), Positives = 361/794 (45%), Gaps = 76/794 (9%)
Query: 1324 EAMFSITSEYNSGARPCLCDFMGSTELECNT-FGGQ--CPCKPNVIGRTCSACRTGYYGF 1380
++ + S+++ G R C C+ S EC GQ C C+ N G C C +
Sbjct: 300 QSYYYAVSDFSVGGR-CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 355
Query: 1381 P----------NCRPCHCPSTAI-CD----------DNGMCI-CPKNVEGENCDRCKPYT 1418
P C PC+C + C G C C + G +C+RC+
Sbjct: 356 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 415
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CY 1476
+++D + C C+C G + LQC+ D+G CAC+ V G CD C+PG ++ + C
Sbjct: 416 YHWDPRMPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 472
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTT 1536
CTCN G+ D CD + +C CK NV G CD C+ FNLQ NP GC+ CFC+G +
Sbjct: 473 PCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 531
Query: 1537 RCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELT-NVTVLTVGLNDGVTNGKV 1595
C+S+ + ++ + + E P+ + N +L+ + +T
Sbjct: 532 VCAST--AQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEELT---- 585
Query: 1596 AYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPP- 1654
APE +LG + SYG L T GD + G L H+S+ P
Sbjct: 586 ----APEKFLGDQRFSYGQPLILTFRVPP-GDSPLPVQLRLEGTGLALSLRHSSLSGPQD 640
Query: 1655 VGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLE 1714
G P ++ +E S P+ F L N++ L +R S S + V
Sbjct: 641 AGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGP-----SPAGPVFL 695
Query: 1715 IGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR-LPSG----FCVPCQCNG 1769
V + A+ VE C CP Y G CE CA G+ R +P G CVPC CN
Sbjct: 696 TEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ 755
Query: 1770 HSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS 1829
H CD NTGIC+ C+ +T G CE C+ G++G+ G DC C CP +
Sbjct: 756 HGT-CDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSAC 807
Query: 1830 CDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPG 1889
+ E+ ++ +C PG G RCE C G++G P H C C CSGN++P G
Sbjct: 808 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCSGNVDPNAVG 866
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK---NCTACICDEFGMAD----CDS 1942
+CD ++G CL+C++NT G C C GFYG A+ + C C C G CD
Sbjct: 867 NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDP 926
Query: 1943 TTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
TG C C P V C RC P + L G GC C C + S+ QC GQC C GV
Sbjct: 927 VTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGV 986
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV 2061
TG+ CD+C GF+ ++ GC C C+ + C+ G C C PG G KCDRC + +
Sbjct: 987 TGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1046
Query: 2062 LIPQ-EGCLECDSC 2074
L C +C SC
Sbjct: 1047 LTADGTHCQQCPSC 1060
Score = 275 bits (675), Expect = 2e-72
Identities = 148/436 (33%), Positives = 218/436 (50%), Gaps = 43/436 (9%)
Query: 34 CDICDANNEAKKHPPEYAVD----DRRTWWQSPPLSRGMKY-NEVNLTIDLGQEFHVAYV 88
C CDA + + H Y D D TWWQSP ++ G++Y VN+T+ LG+ + + YV
Sbjct: 118 CQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYV 177
Query: 89 FVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVI 145
+K S RPE + + K + ++P+Q++S S C++ +G+ + L+P +
Sbjct: 178 RLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQKTYGRPEGQYLRPGEDERVAF 233
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C++E+S I PL G + S L RPS+ + S LQEW +T + + L R +
Sbjct: 234 CTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF 293
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
+DP V + Y+Y++ D S+GGRC CNGHA C P D AG L CRCQHNT G C
Sbjct: 294 ----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGP-DVAGQL---ACRCQHNTTGTDC 345
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
+C F+ + W C PCNC + ECT+D E+ G GG+C
Sbjct: 346 ERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS------TGH---GGRC 396
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
+C+ +T G +C +C+ +Y WD CQPC C S +++G C C+P
Sbjct: 397 HHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTV 451
Query: 386 QPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PCTCN G+ + C P G CPCK N G C+ C G
Sbjct: 452 TGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGT 510
Query: 444 YSPE------CKNCEC 453
++ + C +C C
Sbjct: 511 FNLQPHNPAGCSSCFC 526
Score = 181 bits (441), Expect = 4e-44
Identities = 109/368 (29%), Positives = 161/368 (43%), Gaps = 56/368 (15%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+C C G C C G++++ + Q SC PC C+ H T C DP
Sbjct: 716 ICSCPTGYTGQFCESCAPGYKRE---MPQGGPYASCVPCTCNQHGT-C--DPNT------ 763
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFSTGN 371
G C+ C H+TEG +C +C P +Y P+ + D+ CQPC C +
Sbjct: 764 ----------GICV-CSHHTEGPSCERCLPGFYGNPFAGQADD---CQPCPCPGQSACTT 809
Query: 372 CEE--ESGRCECRPEFQPPDCSSCAYGYFDYP--------NCKPCTC--NLNGTEGEHCT 419
E E C P + C C G+F P C C C N++ +C
Sbjct: 810 IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCD 869
Query: 420 PTDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVS--YVCDKLTG 468
P G C C +N G CE C++G+Y + +C C C+ GSVS CD +TG
Sbjct: 870 PLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 929
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C+C + R C++C G+++ C+ C C G++ C +GQC C+ G G
Sbjct: 930 QCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQ 989
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
CD+C G++ + + C C C P G+ S C +G C C F G +CD+C ++
Sbjct: 990 ACDRCQLGFFGFSI---KGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1046
Query: 586 KYPDCLSC 593
D C
Sbjct: 1047 LTADGTHC 1054
Score = 181 bits (440), Expect = 5e-44
Identities = 104/348 (29%), Positives = 150/348 (43%), Gaps = 44/348 (12%)
Query: 327 NCQHNTEGINCNKCRPTYYR--PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPE 384
+C G C C P Y R P G + C PC C+ H G C+ +G C C
Sbjct: 718 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCNQH---GTCDPNTGICVCSHH 771
Query: 385 FQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCE 437
+ P C C G++ P +C+PC C + +C C G+ CE
Sbjct: 772 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 831
Query: 438 ICEDGYYS--------PE-CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQ 485
+C+DG++ P+ C C+C+ + V CD L+G C C +G C CQ
Sbjct: 832 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 891
Query: 486 AGYYNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYM 536
G+Y C PC+C G+ E CD V+GQC C C +C G++
Sbjct: 892 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 951
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYP--DCLSC 593
GR C C C P GS C G+C C G CD+C G++ + C +C
Sbjct: 952 LQPGRG--CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRAC 1009
Query: 594 NCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY---NYPACEEC 638
C G+ + C +NG C C+ F+G KCD C + F+ + C++C
Sbjct: 1010 RCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1057
Score = 171 bits (416), Expect = 4e-41
Identities = 107/352 (30%), Positives = 152/352 (43%), Gaps = 48/352 (13%)
Query: 379 CECRPEFQPPDCSSCAYGY-------FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
C C + C SCA GY Y +C PCTCN +GT C P G+C C ++
Sbjct: 717 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 772
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQ 483
G SCE C G+Y + +C+ C C + + + + CT C GR C
Sbjct: 773 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 832
Query: 484 CQAGYYNYPT-----CKPCN-CDTSG-TEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
C G++ P +PC+ C SG +P+ CD +SG C+ C G C+ C
Sbjct: 833 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 892
Query: 533 GYYMQVLGRE--RQCVPCNCDPTGSTSTSCSAD---GKCNCLTNFGGAQCDQCSPGYYKY 587
G+Y L +C+PC+C P GS S D G+C+CL + C +C PG++
Sbjct: 893 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDL 952
Query: 588 P---DCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQFYNY--PACEECNCD 641
C SC C GS C G C C+ G CD C+ F+ + C C C
Sbjct: 953 QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCS 1012
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
P G A+ A C C C+ +G C+ C ++ + C+QC
Sbjct: 1013 PLG--AASAQCHE---NGTCVCRPGFEGYKCDRCHDNFFLTADGT--HCQQC 1057
Score = 169 bits (412), Expect = 1e-40
Identities = 106/338 (31%), Positives = 152/338 (44%), Gaps = 43/338 (12%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C+C + Y+G+ C C GY Y +C PC C+ GT CD +G C+C
Sbjct: 717 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 772
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNCD-PTGSTSTSCSADGKC-NCLTNFGGAQCDQ 579
GP C++CL G+Y G+ C PC C + T+ S + C +C G +C+
Sbjct: 773 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 832
Query: 580 CSPGYYKYP--------DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCRE 627
C G++ P C C C +V + CD +G C C N G C+ C+E
Sbjct: 833 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 892
Query: 628 QFYNY-----PA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYW 680
FY PA C C+C P+G + C V G+ C C V R C+ C P ++
Sbjct: 893 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV-TGQ-CSCLPHVTARDCSRCYPGFF 950
Query: 681 NLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDV 740
+LQ GC C C+ G+ C+ K+GQC C+ V + CD+C GF+ +
Sbjct: 951 DLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFFGF---SI 1003
Query: 741 FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
GC C C G+ C + G C C EG +CD+
Sbjct: 1004 KGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDR 1040
Score = 166 bits (404), Expect = 1e-39
Identities = 96/339 (28%), Positives = 146/339 (43%), Gaps = 50/339 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H TC+P N +C C H+T GP C +C GF + + C+P
Sbjct: 751 CTCNQHG-TCDP-------NTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQP 798
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + CT PE E C +C G C C ++
Sbjct: 799 CPCPGQSA-CTTIPESREV--------------VCTHCPPGQRGRRCEVCDDGFFGDPLG 843
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP---- 401
+ C CQC DP+ + GNC+ SG C C C C G++
Sbjct: 844 LFGHPQPCHQCQCSGNVDPN-AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR 902
Query: 402 ---NCKPCTCNLNGTEGEH--CTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCE 452
C PC+C+ G+ E C P G C C + + C C G++ + C++C+
Sbjct: 903 PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCK 962
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICD 510
C+ +GS C TG CTC+ +G+ C++CQ G++ + C+ C C G + C
Sbjct: 963 CHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH 1022
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRE-RQCVPC 548
+ +G C+C+ GF G +CD+C +++ G +QC C
Sbjct: 1023 E-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 1060
Score = 145 bits (352), Expect = 2e-33
Identities = 100/358 (27%), Positives = 145/358 (40%), Gaps = 51/358 (14%)
Query: 424 LCPCKYNYAGKSCEICEDGYYS--PE------CKNCECNTVGSVSYVCDKLTGDCTCKSK 475
+C C Y G+ CE C GY P+ C C CN G+ CD TG C C
Sbjct: 716 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHH 771
Query: 476 YSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
G +C +C G+Y P C+PC C +I + C C G G RC+
Sbjct: 772 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 831
Query: 529 QCLSGYY---MQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCS 581
C G++ + + G + C C C + + D G C CL N G C+ C
Sbjct: 832 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 891
Query: 582 PGYY-------KYPDCLSCNCDVSGSIGST--CDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G+Y C+ C+C GS+ CD G C C + C C F++
Sbjct: 892 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 951
Query: 632 YP---ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
C C C P G C P C C+ V G+ C+ C+ ++ ++
Sbjct: 952 LQPGRGCRSCKCHPLGSQED--QCH--PKTGQCTCRPGVTGQACDRCQLGFFG---FSIK 1004
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC C C+ G ++ C+ ++G CVC+ +CD+C D F+ T D C +C
Sbjct: 1005 GCRACRCSPLGAASA--QCH-ENGTCVCRPGFEGYKCDRCHDNFF--LTADGTHCQQC 1057
Score = 129 bits (312), Expect = 2e-28
Identities = 70/217 (32%), Positives = 99/217 (45%), Gaps = 25/217 (11%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGR-----ERQCVPCNCD 551
C +G DV+GQ C C+ G C++CL + + R +C+PCNC
Sbjct: 315 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 374
Query: 552 PTGSTST-------SCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGS 600
T S G+C+ C + G C++C +Y + C C+C +GS
Sbjct: 375 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGS 434
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRGVTASFAGCGSVPAG 658
+ CDD G C CK G KCD C F++ C C C+P G S C P
Sbjct: 435 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG---SLDTCD--PRS 489
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C CK+ V+G +C+ C+P +NLQ +NP GC C C
Sbjct: 490 GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 526
Score = 121 bits (291), Expect = 6e-26
Identities = 65/201 (32%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSACRTGYYGFP-------NCRPCHC-PSTAI-----CDD- 1396
C+ G C C N G C C+ G+YG C PC C P ++ CD
Sbjct: 868 CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV 927
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
G C C +V +C RC P F+ RGC C C+PLG + QC +G+C CR
Sbjct: 928 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG--SQEDQCHPKTGQCTCRPG 985
Query: 1457 VRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
V G+ CD C G + F C C C+ G C +N C C+ G CD C +
Sbjct: 986 VTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-GTCVCRPGFEGYKCDRCHDN 1044
Query: 1515 YFNLQD-DNPDGCTKCFCFGK 1534
+F D + C C+ K
Sbjct: 1045 FFLTADGTHCQQCPSCYALVK 1065
Score = 113 bits (273), Expect = 9e-24
Identities = 68/227 (29%), Positives = 94/227 (41%), Gaps = 34/227 (14%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P++ G CQHNT G +C +C P + RP+
Sbjct: 315 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERCLPFFQDRPWA 358
Query: 350 KRWDEL-DVCQPCQCDPHFSTGNCEEE-------SGRCE-CRPEFQPPDCSSCAYGYFDY 400
+ E C PC C + E GRC CR P C C ++ +
Sbjct: 359 RGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW 418
Query: 401 -PN--CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE---CKNCECN 454
P C+PC C G+ C T G C CK G C+ C G++S C+ C CN
Sbjct: 419 DPRMPCQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN 477
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
GS+ CD +G C CK G C++C+ G +N P C +
Sbjct: 478 PAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 523
Score = 110 bits (264), Expect = 1e-22
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 33/223 (14%)
Query: 548 CNCDPTGST-STSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S + C C N G C++C P + P +CL CNC
Sbjct: 315 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 374
Query: 597 -------VSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGV 645
+ + G CH C+ + G C+ C+E FY++ C+ C+C G
Sbjct: 375 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAG- 433
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
+ C C CK V G C+ C P + +L E GC C CN AG+L++
Sbjct: 434 -SLHLQCDDTGT---CACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-- 484
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C+ +SG+C CK++V CD+C G + LQ ++ GC+ C C
Sbjct: 485 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 526
Score = 108 bits (259), Expect = 4e-22
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 30/257 (11%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC----EDG 442
P S Y D+ C CN + +E C C++N G CE C +D
Sbjct: 296 PKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 355
Query: 443 YYSP-------ECKNCECN------TVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGY 488
++ EC C C+ T + G C C+ +G C +CQ +
Sbjct: 356 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 415
Query: 489 YNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
Y++ C+PC+C ++G+ CDD +G C CK G +CD+CL G++ E C
Sbjct: 416 YHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSL---SEGGC 471
Query: 546 VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDVSGS 600
PC C+P GS T G+C C N G CD+C PG + C SC C
Sbjct: 472 RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 531
Query: 601 IGSTCDDNGLCHCKSNF 617
+ ++ + H S+F
Sbjct: 532 VCASTAQFQVHHILSDF 548
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 593 CNCDVSGS-IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C C+ S G C C+ N G C+ C F + P C CNC
Sbjct: 315 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 374
Query: 642 PRGVTASFAG--CGSVPAGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA 698
R +F S G C C+D G C C+ +++ P C+ C+C A
Sbjct: 375 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSA 432
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
G+L+ C+ +G C CK V +CD+CL GF+ L GC C C+ GS+D C
Sbjct: 433 GSLHL--QCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-C 485
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D +G+C C VEG CD+
Sbjct: 486 DPRSGRCPCKENVEGNLCDR 505
Score = 89.0 bits (211), Expect = 3e-16
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + C F + + G R C C +GS E +C+ GQC C+P V G+ C
Sbjct: 936 HVTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 993
Query: 1373 CRTGYYGF--PNCRPCHC----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C+ G++GF CR C C ++A C +NG C+C EG CDRC F
Sbjct: 994 CQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTH 1053
Query: 1427 CDDC 1430
C C
Sbjct: 1054 CQQC 1057
Score = 65.7 bits (153), Expect = 3e-09
Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLY-WNLQEYNPF-GCEQCNCNLAGTLNSLGACNTKSGQCVC 716
E+C C G+ C C P Y + + P+ C C CN GT C+ +G CVC
Sbjct: 715 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 768
Query: 717 KQHVGERQCDQCLDGFY-RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGR 774
H C++CL GFY C C C + + C HC GR
Sbjct: 769 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 828
Query: 775 RCD 777
RC+
Sbjct: 829 RCE 831
Score = 56.0 bits (129), Expect = 2e-06
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 1316 PNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
P TG C + S G RPC C+ GS + C+ G+CPCK NV G C CR
Sbjct: 449 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 507
Query: 1375 TGYYGFPNCRPCHCPSTAICDDNGMC 1400
G + P C S + +C
Sbjct: 508 PGTFNLQPHNPAGCSSCFCYGHSKVC 533
Score = 39.1 bits (87), Expect = 0.30
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Query: 714 CVCKQHVGERQCDQCLDGFYRL--QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRV 771
C C + C+ C G+ R Q C C C+ G+ CD TG C C
Sbjct: 717 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 772
Query: 772 EGRRCDQPIRAHY 784
EG C++ + Y
Sbjct: 773 EGPSCERCLPGFY 785
>AL355872-3|CAI39529.1| 1587|Homo sapiens laminin, gamma 3 protein.
Length = 1587
Score = 411 bits (1012), Expect = e-113
Identities = 257/794 (32%), Positives = 361/794 (45%), Gaps = 76/794 (9%)
Query: 1324 EAMFSITSEYNSGARPCLCDFMGSTELECNT-FGGQ--CPCKPNVIGRTCSACRTGYYGF 1380
++ + S+++ G R C C+ S EC GQ C C+ N G C C +
Sbjct: 256 QSYYYAVSDFSVGGR-CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 1381 P----------NCRPCHCPSTAI-CD----------DNGMCI-CPKNVEGENCDRCKPYT 1418
P C PC+C + C G C C + G +C+RC+
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CY 1476
+++D + C C+C G + LQC+ D+G CAC+ V G CD C+PG ++ + C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 428
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTT 1536
CTCN G+ D CD + +C CK NV G CD C+ FNLQ NP GC+ CFC+G +
Sbjct: 429 PCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 487
Query: 1537 RCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELT-NVTVLTVGLNDGVTNGKV 1595
C+S+ + ++ + + E P+ + N +L+ + +T
Sbjct: 488 VCAST--AQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEELT---- 541
Query: 1596 AYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPP- 1654
APE +LG + SYG L T GD + G L H+S+ P
Sbjct: 542 ----APEKFLGDQRFSYGQPLILTFRVPP-GDSPLPVQLRLEGTGLALSLRHSSLSGPQD 596
Query: 1655 VGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLE 1714
G P ++ +E S P+ F L N++ L +R S S + V
Sbjct: 597 AGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGP-----SPAGPVFL 651
Query: 1715 IGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR-LPSG----FCVPCQCNG 1769
V + A+ VE C CP Y G CE CA G+ R +P G CVPC CN
Sbjct: 652 TEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ 711
Query: 1770 HSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS 1829
H CD NTGIC+ C+ +T G CE C+ G++G+ G DC C CP +
Sbjct: 712 HGT-CDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSAC 763
Query: 1830 CDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPG 1889
+ E+ ++ +C PG G RCE C G++G P H C C CSGN++P G
Sbjct: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCSGNVDPNAVG 822
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK---NCTACICDEFGMAD----CDS 1942
+CD ++G CL+C++NT G C C GFYG A+ + C C C G CD
Sbjct: 823 NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDP 882
Query: 1943 TTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
TG C C P V C RC P + L G GC C C + S+ QC GQC C GV
Sbjct: 883 VTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGV 942
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV 2061
TG+ CD+C GF+ ++ GC C C+ + C+ G C C PG G KCDRC + +
Sbjct: 943 TGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1002
Query: 2062 LIPQ-EGCLECDSC 2074
L C +C SC
Sbjct: 1003 LTADGTHCQQCPSC 1016
Score = 275 bits (675), Expect = 2e-72
Identities = 148/436 (33%), Positives = 218/436 (50%), Gaps = 43/436 (9%)
Query: 34 CDICDANNEAKKHPPEYAVD----DRRTWWQSPPLSRGMKY-NEVNLTIDLGQEFHVAYV 88
C CDA + + H Y D D TWWQSP ++ G++Y VN+T+ LG+ + + YV
Sbjct: 74 CQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYV 133
Query: 89 FVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVI 145
+K S RPE + + K + ++P+Q++S S C++ +G+ + L+P +
Sbjct: 134 RLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQKTYGRPEGQYLRPGEDERVAF 189
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C++E+S I PL G + S L RPS+ + S LQEW +T + + L R +
Sbjct: 190 CTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF 249
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
+DP V + Y+Y++ D S+GGRC CNGHA C P D AG L CRCQHNT G C
Sbjct: 250 ----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGP-DVAGQL---ACRCQHNTTGTDC 301
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
+C F+ + W C PCNC + ECT+D E+ G GG+C
Sbjct: 302 ERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS------TGH---GGRC 352
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
+C+ +T G +C +C+ +Y WD CQPC C S +++G C C+P
Sbjct: 353 HHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTV 407
Query: 386 QPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PCTCN G+ + C P G CPCK N G C+ C G
Sbjct: 408 TGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGT 466
Query: 444 YSPE------CKNCEC 453
++ + C +C C
Sbjct: 467 FNLQPHNPAGCSSCFC 482
Score = 181 bits (441), Expect = 4e-44
Identities = 109/368 (29%), Positives = 161/368 (43%), Gaps = 56/368 (15%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+C C G C C G++++ + Q SC PC C+ H T C DP
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKRE---MPQGGPYASCVPCTCNQHGT-C--DPNT------ 719
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFSTGN 371
G C+ C H+TEG +C +C P +Y P+ + D+ CQPC C +
Sbjct: 720 ----------GICV-CSHHTEGPSCERCLPGFYGNPFAGQADD---CQPCPCPGQSACTT 765
Query: 372 CEE--ESGRCECRPEFQPPDCSSCAYGYFDYP--------NCKPCTC--NLNGTEGEHCT 419
E E C P + C C G+F P C C C N++ +C
Sbjct: 766 IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCD 825
Query: 420 PTDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVS--YVCDKLTG 468
P G C C +N G CE C++G+Y + +C C C+ GSVS CD +TG
Sbjct: 826 PLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 885
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C+C + R C++C G+++ C+ C C G++ C +GQC C+ G G
Sbjct: 886 QCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQ 945
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
CD+C G++ + + C C C P G+ S C +G C C F G +CD+C ++
Sbjct: 946 ACDRCQLGFFGFSI---KGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1002
Query: 586 KYPDCLSC 593
D C
Sbjct: 1003 LTADGTHC 1010
Score = 181 bits (440), Expect = 5e-44
Identities = 104/348 (29%), Positives = 150/348 (43%), Gaps = 44/348 (12%)
Query: 327 NCQHNTEGINCNKCRPTYYR--PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPE 384
+C G C C P Y R P G + C PC C+ H G C+ +G C C
Sbjct: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCNQH---GTCDPNTGICVCSHH 727
Query: 385 FQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCE 437
+ P C C G++ P +C+PC C + +C C G+ CE
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 438 ICEDGYYS--------PE-CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQ 485
+C+DG++ P+ C C+C+ + V CD L+G C C +G C CQ
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Query: 486 AGYYNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYM 536
G+Y C PC+C G+ E CD V+GQC C C +C G++
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYP--DCLSC 593
GR C C C P GS C G+C C G CD+C G++ + C +C
Sbjct: 908 LQPGRG--CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRAC 965
Query: 594 NCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY---NYPACEEC 638
C G+ + C +NG C C+ F+G KCD C + F+ + C++C
Sbjct: 966 RCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 171 bits (416), Expect = 4e-41
Identities = 107/352 (30%), Positives = 152/352 (43%), Gaps = 48/352 (13%)
Query: 379 CECRPEFQPPDCSSCAYGY-------FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
C C + C SCA GY Y +C PCTCN +GT C P G+C C ++
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQ 483
G SCE C G+Y + +C+ C C + + + + CT C GR C
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
Query: 484 CQAGYYNYPT-----CKPCN-CDTSG-TEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
C G++ P +PC+ C SG +P+ CD +SG C+ C G C+ C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 848
Query: 533 GYYMQVLGRE--RQCVPCNCDPTGSTSTSCSAD---GKCNCLTNFGGAQCDQCSPGYYKY 587
G+Y L +C+PC+C P GS S D G+C+CL + C +C PG++
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDL 908
Query: 588 P---DCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQFYNY--PACEECNCD 641
C SC C GS C G C C+ G CD C+ F+ + C C C
Sbjct: 909 QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCS 968
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
P G A+ A C C C+ +G C+ C ++ + C+QC
Sbjct: 969 PLG--AASAQCHE---NGTCVCRPGFEGYKCDRCHDNFFLTADGT--HCQQC 1013
Score = 169 bits (412), Expect = 1e-40
Identities = 106/338 (31%), Positives = 152/338 (44%), Gaps = 43/338 (12%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C+C + Y+G+ C C GY Y +C PC C+ GT CD +G C+C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNCD-PTGSTSTSCSADGKC-NCLTNFGGAQCDQ 579
GP C++CL G+Y G+ C PC C + T+ S + C +C G +C+
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
Query: 580 CSPGYYKYP--------DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCRE 627
C G++ P C C C +V + CD +G C C N G C+ C+E
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 848
Query: 628 QFYNY-----PA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYW 680
FY PA C C+C P+G + C V G+ C C V R C+ C P ++
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV-TGQ-CSCLPHVTARDCSRCYPGFF 906
Query: 681 NLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDV 740
+LQ GC C C+ G+ C+ K+GQC C+ V + CD+C GF+ +
Sbjct: 907 DLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFFGF---SI 959
Query: 741 FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
GC C C G+ C + G C C EG +CD+
Sbjct: 960 KGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDR 996
Score = 166 bits (404), Expect = 1e-39
Identities = 96/339 (28%), Positives = 146/339 (43%), Gaps = 50/339 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H TC+P N +C C H+T GP C +C GF + + C+P
Sbjct: 707 CTCNQHG-TCDP-------NTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQP 754
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + CT PE E C +C G C C ++
Sbjct: 755 CPCPGQSA-CTTIPESREV--------------VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP---- 401
+ C CQC DP+ + GNC+ SG C C C C G++
Sbjct: 800 LFGHPQPCHQCQCSGNVDPN-AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR 858
Query: 402 ---NCKPCTCNLNGTEGEH--CTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCE 452
C PC+C+ G+ E C P G C C + + C C G++ + C++C+
Sbjct: 859 PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCK 918
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICD 510
C+ +GS C TG CTC+ +G+ C++CQ G++ + C+ C C G + C
Sbjct: 919 CHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH 978
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRE-RQCVPC 548
+ +G C+C+ GF G +CD+C +++ G +QC C
Sbjct: 979 E-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 1016
Score = 145 bits (352), Expect = 2e-33
Identities = 100/358 (27%), Positives = 145/358 (40%), Gaps = 51/358 (14%)
Query: 424 LCPCKYNYAGKSCEICEDGYYS--PE------CKNCECNTVGSVSYVCDKLTGDCTCKSK 475
+C C Y G+ CE C GY P+ C C CN G+ CD TG C C
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHH 727
Query: 476 YSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
G +C +C G+Y P C+PC C +I + C C G G RC+
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 529 QCLSGYY---MQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCS 581
C G++ + + G + C C C + + D G C CL N G C+ C
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Query: 582 PGYY-------KYPDCLSCNCDVSGSIGST--CDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G+Y C+ C+C GS+ CD G C C + C C F++
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
Query: 632 YP---ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
C C C P G C P C C+ V G+ C+ C+ ++ ++
Sbjct: 908 LQPGRGCRSCKCHPLGSQED--QCH--PKTGQCTCRPGVTGQACDRCQLGFFG---FSIK 960
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC C C+ G ++ C+ ++G CVC+ +CD+C D F+ T D C +C
Sbjct: 961 GCRACRCSPLGAASA--QCH-ENGTCVCRPGFEGYKCDRCHDNFF--LTADGTHCQQC 1013
Score = 129 bits (312), Expect = 2e-28
Identities = 70/217 (32%), Positives = 99/217 (45%), Gaps = 25/217 (11%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGR-----ERQCVPCNCD 551
C +G DV+GQ C C+ G C++CL + + R +C+PCNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 552 PTGSTST-------SCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGS 600
T S G+C+ C + G C++C +Y + C C+C +GS
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGS 390
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRGVTASFAGCGSVPAG 658
+ CDD G C CK G KCD C F++ C C C+P G S C P
Sbjct: 391 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG---SLDTCD--PRS 445
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C CK+ V+G +C+ C+P +NLQ +NP GC C C
Sbjct: 446 GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 121 bits (291), Expect = 6e-26
Identities = 65/201 (32%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSACRTGYYGFP-------NCRPCHC-PSTAI-----CDD- 1396
C+ G C C N G C C+ G+YG C PC C P ++ CD
Sbjct: 824 CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV 883
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
G C C +V +C RC P F+ RGC C C+PLG + QC +G+C CR
Sbjct: 884 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG--SQEDQCHPKTGQCTCRPG 941
Query: 1457 VRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
V G+ CD C G + F C C C+ G C +N C C+ G CD C +
Sbjct: 942 VTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-GTCVCRPGFEGYKCDRCHDN 1000
Query: 1515 YFNLQD-DNPDGCTKCFCFGK 1534
+F D + C C+ K
Sbjct: 1001 FFLTADGTHCQQCPSCYALVK 1021
Score = 113 bits (273), Expect = 9e-24
Identities = 68/227 (29%), Positives = 94/227 (41%), Gaps = 34/227 (14%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P++ G CQHNT G +C +C P + RP+
Sbjct: 271 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERCLPFFQDRPWA 314
Query: 350 KRWDEL-DVCQPCQCDPHFSTGNCEEE-------SGRCE-CRPEFQPPDCSSCAYGYFDY 400
+ E C PC C + E GRC CR P C C ++ +
Sbjct: 315 RGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW 374
Query: 401 -PN--CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE---CKNCECN 454
P C+PC C G+ C T G C CK G C+ C G++S C+ C CN
Sbjct: 375 DPRMPCQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN 433
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
GS+ CD +G C CK G C++C+ G +N P C +
Sbjct: 434 PAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
Score = 110 bits (264), Expect = 1e-22
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 33/223 (14%)
Query: 548 CNCDPTGST-STSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S + C C N G C++C P + P +CL CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 597 -------VSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGV 645
+ + G CH C+ + G C+ C+E FY++ C+ C+C G
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAG- 389
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
+ C C CK V G C+ C P + +L E GC C CN AG+L++
Sbjct: 390 -SLHLQCDDTGT---CACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-- 440
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C+ +SG+C CK++V CD+C G + LQ ++ GC+ C C
Sbjct: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 108 bits (259), Expect = 4e-22
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 30/257 (11%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC----EDG 442
P S Y D+ C CN + +E C C++N G CE C +D
Sbjct: 252 PKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 443 YYSP-------ECKNCECN------TVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGY 488
++ EC C C+ T + G C C+ +G C +CQ +
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 489 YNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
Y++ C+PC+C ++G+ CDD +G C CK G +CD+CL G++ E C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSL---SEGGC 427
Query: 546 VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDVSGS 600
PC C+P GS T G+C C N G CD+C PG + C SC C
Sbjct: 428 RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 487
Query: 601 IGSTCDDNGLCHCKSNF 617
+ ++ + H S+F
Sbjct: 488 VCASTAQFQVHHILSDF 504
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 593 CNCDVSGS-IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C C+ S G C C+ N G C+ C F + P C CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 642 PRGVTASFAG--CGSVPAGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA 698
R +F S G C C+D G C C+ +++ P C+ C+C A
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSA 388
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
G+L+ C+ +G C CK V +CD+CL GF+ L GC C C+ GS+D C
Sbjct: 389 GSLHL--QCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-C 441
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D +G+C C VEG CD+
Sbjct: 442 DPRSGRCPCKENVEGNLCDR 461
Score = 89.0 bits (211), Expect = 3e-16
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + C F + + G R C C +GS E +C+ GQC C+P V G+ C
Sbjct: 892 HVTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 949
Query: 1373 CRTGYYGF--PNCRPCHC----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C+ G++GF CR C C ++A C +NG C+C EG CDRC F
Sbjct: 950 CQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTH 1009
Query: 1427 CDDC 1430
C C
Sbjct: 1010 CQQC 1013
Score = 65.7 bits (153), Expect = 3e-09
Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLY-WNLQEYNPF-GCEQCNCNLAGTLNSLGACNTKSGQCVC 716
E+C C G+ C C P Y + + P+ C C CN GT C+ +G CVC
Sbjct: 671 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 724
Query: 717 KQHVGERQCDQCLDGFY-RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGR 774
H C++CL GFY C C C + + C HC GR
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 784
Query: 775 RCD 777
RC+
Sbjct: 785 RCE 787
Score = 56.0 bits (129), Expect = 2e-06
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 1316 PNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
P TG C + S G RPC C+ GS + C+ G+CPCK NV G C CR
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
Query: 1375 TGYYGFPNCRPCHCPSTAICDDNGMC 1400
G + P C S + +C
Sbjct: 464 PGTFNLQPHNPAGCSSCFCYGHSKVC 489
Score = 39.1 bits (87), Expect = 0.30
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Query: 714 CVCKQHVGERQCDQCLDGFYRL--QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRV 771
C C + C+ C G+ R Q C C C+ G+ CD TG C C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 772 EGRRCDQPIRAHY 784
EG C++ + Y
Sbjct: 729 EGPSCERCLPGFY 741
>AL355872-2|CAI39530.2| 1619|Homo sapiens laminin, gamma 3 protein.
Length = 1619
Score = 411 bits (1012), Expect = e-113
Identities = 257/794 (32%), Positives = 361/794 (45%), Gaps = 76/794 (9%)
Query: 1324 EAMFSITSEYNSGARPCLCDFMGSTELECNT-FGGQ--CPCKPNVIGRTCSACRTGYYGF 1380
++ + S+++ G R C C+ S EC GQ C C+ N G C C +
Sbjct: 300 QSYYYAVSDFSVGGR-CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 355
Query: 1381 P----------NCRPCHCPSTAI-CD----------DNGMCI-CPKNVEGENCDRCKPYT 1418
P C PC+C + C G C C + G +C+RC+
Sbjct: 356 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 415
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CY 1476
+++D + C C+C G + LQC+ D+G CAC+ V G CD C+PG ++ + C
Sbjct: 416 YHWDPRMPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 472
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTT 1536
CTCN G+ D CD + +C CK NV G CD C+ FNLQ NP GC+ CFC+G +
Sbjct: 473 PCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 531
Query: 1537 RCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVPELT-NVTVLTVGLNDGVTNGKV 1595
C+S+ + ++ + + E P+ + N +L+ + +T
Sbjct: 532 VCAST--AQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEELT---- 585
Query: 1596 AYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPP- 1654
APE +LG + SYG L T GD + G L H+S+ P
Sbjct: 586 ----APEKFLGDQRFSYGQPLILTFRVPP-GDSPLPVQLRLEGTGLALSLRHSSLSGPQD 640
Query: 1655 VGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLE 1714
G P ++ +E S P+ F L N++ L +R S S + V
Sbjct: 641 AGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGP-----SPAGPVFL 695
Query: 1715 IGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR-LPSG----FCVPCQCNG 1769
V + A+ VE C CP Y G CE CA G+ R +P G CVPC CN
Sbjct: 696 TEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ 755
Query: 1770 HSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS 1829
H CD NTGIC+ C+ +T G CE C+ G++G+ G DC C CP +
Sbjct: 756 HGT-CDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSAC 807
Query: 1830 CDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPG 1889
+ E+ ++ +C PG G RCE C G++G P H C C CSGN++P G
Sbjct: 808 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCSGNVDPNAVG 866
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK---NCTACICDEFGMAD----CDS 1942
+CD ++G CL+C++NT G C C GFYG A+ + C C C G CD
Sbjct: 867 NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDP 926
Query: 1943 TTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
TG C C P V C RC P + L G GC C C + S+ QC GQC C GV
Sbjct: 927 VTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGV 986
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV 2061
TG+ CD+C GF+ ++ GC C C+ + C+ G C C PG G KCDRC + +
Sbjct: 987 TGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1046
Query: 2062 LIPQ-EGCLECDSC 2074
L C +C SC
Sbjct: 1047 LTADGTHCQQCPSC 1060
Score = 275 bits (675), Expect = 2e-72
Identities = 148/436 (33%), Positives = 218/436 (50%), Gaps = 43/436 (9%)
Query: 34 CDICDANNEAKKHPPEYAVD----DRRTWWQSPPLSRGMKY-NEVNLTIDLGQEFHVAYV 88
C CDA + + H Y D D TWWQSP ++ G++Y VN+T+ LG+ + + YV
Sbjct: 118 CQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYV 177
Query: 89 FVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVI 145
+K S RPE + + K + ++P+Q++S S C++ +G+ + L+P +
Sbjct: 178 RLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQKTYGRPEGQYLRPGEDERVAF 233
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C++E+S I PL G + S L RPS+ + S LQEW +T + + L R +
Sbjct: 234 CTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF 293
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
+DP V + Y+Y++ D S+GGRC CNGHA C P D AG L CRCQHNT G C
Sbjct: 294 ----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGP-DVAGQL---ACRCQHNTTGTDC 345
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
+C F+ + W C PCNC + ECT+D E+ G GG+C
Sbjct: 346 ERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS------TGH---GGRC 396
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
+C+ +T G +C +C+ +Y WD CQPC C S +++G C C+P
Sbjct: 397 HHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTV 451
Query: 386 QPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PCTCN G+ + C P G CPCK N G C+ C G
Sbjct: 452 TGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGT 510
Query: 444 YSPE------CKNCEC 453
++ + C +C C
Sbjct: 511 FNLQPHNPAGCSSCFC 526
Score = 181 bits (441), Expect = 4e-44
Identities = 109/368 (29%), Positives = 161/368 (43%), Gaps = 56/368 (15%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+C C G C C G++++ + Q SC PC C+ H T C DP
Sbjct: 716 ICSCPTGYTGQFCESCAPGYKRE---MPQGGPYASCVPCTCNQHGT-C--DPNT------ 763
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFSTGN 371
G C+ C H+TEG +C +C P +Y P+ + D+ CQPC C +
Sbjct: 764 ----------GICV-CSHHTEGPSCERCLPGFYGNPFAGQADD---CQPCPCPGQSACTT 809
Query: 372 CEE--ESGRCECRPEFQPPDCSSCAYGYFDYP--------NCKPCTC--NLNGTEGEHCT 419
E E C P + C C G+F P C C C N++ +C
Sbjct: 810 IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCD 869
Query: 420 PTDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVS--YVCDKLTG 468
P G C C +N G CE C++G+Y + +C C C+ GSVS CD +TG
Sbjct: 870 PLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 929
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C+C + R C++C G+++ C+ C C G++ C +GQC C+ G G
Sbjct: 930 QCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQ 989
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
CD+C G++ + + C C C P G+ S C +G C C F G +CD+C ++
Sbjct: 990 ACDRCQLGFFGFSI---KGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFF 1046
Query: 586 KYPDCLSC 593
D C
Sbjct: 1047 LTADGTHC 1054
Score = 181 bits (440), Expect = 5e-44
Identities = 104/348 (29%), Positives = 150/348 (43%), Gaps = 44/348 (12%)
Query: 327 NCQHNTEGINCNKCRPTYYR--PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPE 384
+C G C C P Y R P G + C PC C+ H G C+ +G C C
Sbjct: 718 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCNQH---GTCDPNTGICVCSHH 771
Query: 385 FQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCE 437
+ P C C G++ P +C+PC C + +C C G+ CE
Sbjct: 772 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 831
Query: 438 ICEDGYYS--------PE-CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQCQ 485
+C+DG++ P+ C C+C+ + V CD L+G C C +G C CQ
Sbjct: 832 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 891
Query: 486 AGYYNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGYYM 536
G+Y C PC+C G+ E CD V+GQC C C +C G++
Sbjct: 892 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 951
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYP--DCLSC 593
GR C C C P GS C G+C C G CD+C G++ + C +C
Sbjct: 952 LQPGRG--CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRAC 1009
Query: 594 NCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY---NYPACEEC 638
C G+ + C +NG C C+ F+G KCD C + F+ + C++C
Sbjct: 1010 RCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1057
Score = 171 bits (416), Expect = 4e-41
Identities = 107/352 (30%), Positives = 152/352 (43%), Gaps = 48/352 (13%)
Query: 379 CECRPEFQPPDCSSCAYGY-------FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
C C + C SCA GY Y +C PCTCN +GT C P G+C C ++
Sbjct: 717 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 772
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQ 483
G SCE C G+Y + +C+ C C + + + + CT C GR C
Sbjct: 773 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 832
Query: 484 CQAGYYNYPT-----CKPCN-CDTSG-TEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
C G++ P +PC+ C SG +P+ CD +SG C+ C G C+ C
Sbjct: 833 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 892
Query: 533 GYYMQVLGRE--RQCVPCNCDPTGSTSTSCSAD---GKCNCLTNFGGAQCDQCSPGYYKY 587
G+Y L +C+PC+C P GS S D G+C+CL + C +C PG++
Sbjct: 893 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDL 952
Query: 588 P---DCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQFYNY--PACEECNCD 641
C SC C GS C G C C+ G CD C+ F+ + C C C
Sbjct: 953 QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCS 1012
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
P G A+ A C C C+ +G C+ C ++ + C+QC
Sbjct: 1013 PLG--AASAQCHE---NGTCVCRPGFEGYKCDRCHDNFFLTADGT--HCQQC 1057
Score = 169 bits (412), Expect = 1e-40
Identities = 106/338 (31%), Positives = 152/338 (44%), Gaps = 43/338 (12%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C+C + Y+G+ C C GY Y +C PC C+ GT CD +G C+C
Sbjct: 717 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 772
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNCD-PTGSTSTSCSADGKC-NCLTNFGGAQCDQ 579
GP C++CL G+Y G+ C PC C + T+ S + C +C G +C+
Sbjct: 773 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 832
Query: 580 CSPGYYKYP--------DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCRE 627
C G++ P C C C +V + CD +G C C N G C+ C+E
Sbjct: 833 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 892
Query: 628 QFYNY-----PA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYW 680
FY PA C C+C P+G + C V G+ C C V R C+ C P ++
Sbjct: 893 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV-TGQ-CSCLPHVTARDCSRCYPGFF 950
Query: 681 NLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDV 740
+LQ GC C C+ G+ C+ K+GQC C+ V + CD+C GF+ +
Sbjct: 951 DLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFFGF---SI 1003
Query: 741 FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
GC C C G+ C + G C C EG +CD+
Sbjct: 1004 KGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDR 1040
Score = 166 bits (404), Expect = 1e-39
Identities = 96/339 (28%), Positives = 146/339 (43%), Gaps = 50/339 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H TC+P N +C C H+T GP C +C GF + + C+P
Sbjct: 751 CTCNQHG-TCDP-------NTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQP 798
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + CT PE E C +C G C C ++
Sbjct: 799 CPCPGQSA-CTTIPESREV--------------VCTHCPPGQRGRRCEVCDDGFFGDPLG 843
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP---- 401
+ C CQC DP+ + GNC+ SG C C C C G++
Sbjct: 844 LFGHPQPCHQCQCSGNVDPN-AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR 902
Query: 402 ---NCKPCTCNLNGTEGEH--CTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCE 452
C PC+C+ G+ E C P G C C + + C C G++ + C++C+
Sbjct: 903 PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCK 962
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICD 510
C+ +GS C TG CTC+ +G+ C++CQ G++ + C+ C C G + C
Sbjct: 963 CHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH 1022
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRE-RQCVPC 548
+ +G C+C+ GF G +CD+C +++ G +QC C
Sbjct: 1023 E-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 1060
Score = 145 bits (352), Expect = 2e-33
Identities = 100/358 (27%), Positives = 145/358 (40%), Gaps = 51/358 (14%)
Query: 424 LCPCKYNYAGKSCEICEDGYYS--PE------CKNCECNTVGSVSYVCDKLTGDCTCKSK 475
+C C Y G+ CE C GY P+ C C CN G+ CD TG C C
Sbjct: 716 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHH 771
Query: 476 YSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
G +C +C G+Y P C+PC C +I + C C G G RC+
Sbjct: 772 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 831
Query: 529 QCLSGYY---MQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCS 581
C G++ + + G + C C C + + D G C CL N G C+ C
Sbjct: 832 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 891
Query: 582 PGYY-------KYPDCLSCNCDVSGSIGST--CDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G+Y C+ C+C GS+ CD G C C + C C F++
Sbjct: 892 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 951
Query: 632 YP---ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
C C C P G C P C C+ V G+ C+ C+ ++ ++
Sbjct: 952 LQPGRGCRSCKCHPLGSQED--QCH--PKTGQCTCRPGVTGQACDRCQLGFFG---FSIK 1004
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC C C+ G ++ C+ ++G CVC+ +CD+C D F+ T D C +C
Sbjct: 1005 GCRACRCSPLGAASA--QCH-ENGTCVCRPGFEGYKCDRCHDNFF--LTADGTHCQQC 1057
Score = 129 bits (312), Expect = 2e-28
Identities = 70/217 (32%), Positives = 99/217 (45%), Gaps = 25/217 (11%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGR-----ERQCVPCNCD 551
C +G DV+GQ C C+ G C++CL + + R +C+PCNC
Sbjct: 315 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 374
Query: 552 PTGSTST-------SCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGS 600
T S G+C+ C + G C++C +Y + C C+C +GS
Sbjct: 375 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGS 434
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRGVTASFAGCGSVPAG 658
+ CDD G C CK G KCD C F++ C C C+P G S C P
Sbjct: 435 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG---SLDTCD--PRS 489
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C CK+ V+G +C+ C+P +NLQ +NP GC C C
Sbjct: 490 GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 526
Score = 121 bits (291), Expect = 6e-26
Identities = 65/201 (32%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSACRTGYYGFP-------NCRPCHC-PSTAI-----CDD- 1396
C+ G C C N G C C+ G+YG C PC C P ++ CD
Sbjct: 868 CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV 927
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
G C C +V +C RC P F+ RGC C C+PLG + QC +G+C CR
Sbjct: 928 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG--SQEDQCHPKTGQCTCRPG 985
Query: 1457 VRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
V G+ CD C G + F C C C+ G C +N C C+ G CD C +
Sbjct: 986 VTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-GTCVCRPGFEGYKCDRCHDN 1044
Query: 1515 YFNLQD-DNPDGCTKCFCFGK 1534
+F D + C C+ K
Sbjct: 1045 FFLTADGTHCQQCPSCYALVK 1065
Score = 113 bits (273), Expect = 9e-24
Identities = 68/227 (29%), Positives = 94/227 (41%), Gaps = 34/227 (14%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P++ G CQHNT G +C +C P + RP+
Sbjct: 315 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERCLPFFQDRPWA 358
Query: 350 KRWDEL-DVCQPCQCDPHFSTGNCEEE-------SGRCE-CRPEFQPPDCSSCAYGYFDY 400
+ E C PC C + E GRC CR P C C ++ +
Sbjct: 359 RGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW 418
Query: 401 -PN--CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE---CKNCECN 454
P C+PC C G+ C T G C CK G C+ C G++S C+ C CN
Sbjct: 419 DPRMPCQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN 477
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
GS+ CD +G C CK G C++C+ G +N P C +
Sbjct: 478 PAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 523
Score = 110 bits (264), Expect = 1e-22
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 33/223 (14%)
Query: 548 CNCDPTGST-STSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S + C C N G C++C P + P +CL CNC
Sbjct: 315 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 374
Query: 597 -------VSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGV 645
+ + G CH C+ + G C+ C+E FY++ C+ C+C G
Sbjct: 375 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAG- 433
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
+ C C CK V G C+ C P + +L E GC C CN AG+L++
Sbjct: 434 -SLHLQCDDTGT---CACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-- 484
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C+ +SG+C CK++V CD+C G + LQ ++ GC+ C C
Sbjct: 485 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 526
Score = 108 bits (259), Expect = 4e-22
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 30/257 (11%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC----EDG 442
P S Y D+ C CN + +E C C++N G CE C +D
Sbjct: 296 PKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 355
Query: 443 YYSP-------ECKNCECN------TVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGY 488
++ EC C C+ T + G C C+ +G C +CQ +
Sbjct: 356 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 415
Query: 489 YNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
Y++ C+PC+C ++G+ CDD +G C CK G +CD+CL G++ E C
Sbjct: 416 YHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSL---SEGGC 471
Query: 546 VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDVSGS 600
PC C+P GS T G+C C N G CD+C PG + C SC C
Sbjct: 472 RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 531
Query: 601 IGSTCDDNGLCHCKSNF 617
+ ++ + H S+F
Sbjct: 532 VCASTAQFQVHHILSDF 548
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 593 CNCDVSGS-IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C C+ S G C C+ N G C+ C F + P C CNC
Sbjct: 315 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 374
Query: 642 PRGVTASFAG--CGSVPAGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA 698
R +F S G C C+D G C C+ +++ P C+ C+C A
Sbjct: 375 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSA 432
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
G+L+ C+ +G C CK V +CD+CL GF+ L GC C C+ GS+D C
Sbjct: 433 GSLHL--QCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-C 485
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D +G+C C VEG CD+
Sbjct: 486 DPRSGRCPCKENVEGNLCDR 505
Score = 89.0 bits (211), Expect = 3e-16
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 8/124 (6%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + C F + + G R C C +GS E +C+ GQC C+P V G+ C
Sbjct: 936 HVTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 993
Query: 1373 CRTGYYGF--PNCRPCHC----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
C+ G++GF CR C C ++A C +NG C+C EG CDRC F
Sbjct: 994 CQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTH 1053
Query: 1427 CDDC 1430
C C
Sbjct: 1054 CQQC 1057
Score = 65.7 bits (153), Expect = 3e-09
Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLY-WNLQEYNPF-GCEQCNCNLAGTLNSLGACNTKSGQCVC 716
E+C C G+ C C P Y + + P+ C C CN GT C+ +G CVC
Sbjct: 715 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 768
Query: 717 KQHVGERQCDQCLDGFY-RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGR 774
H C++CL GFY C C C + + C HC GR
Sbjct: 769 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 828
Query: 775 RCD 777
RC+
Sbjct: 829 RCE 831
Score = 56.0 bits (129), Expect = 2e-06
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 1316 PNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
P TG C + S G RPC C+ GS + C+ G+CPCK NV G C CR
Sbjct: 449 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 507
Query: 1375 TGYYGFPNCRPCHCPSTAICDDNGMC 1400
G + P C S + +C
Sbjct: 508 PGTFNLQPHNPAGCSSCFCYGHSKVC 533
Score = 39.1 bits (87), Expect = 0.30
Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Query: 714 CVCKQHVGERQCDQCLDGFYRL--QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRV 771
C C + C+ C G+ R Q C C C+ G+ CD TG C C
Sbjct: 717 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 772
Query: 772 EGRRCDQPIRAHY 784
EG C++ + Y
Sbjct: 773 EGPSCERCLPGFY 785
>AF041835-1|AAD36991.1| 1587|Homo sapiens laminin gamma 3 chain
precursor protein.
Length = 1587
Score = 399 bits (983), Expect = e-110
Identities = 256/795 (32%), Positives = 359/795 (45%), Gaps = 78/795 (9%)
Query: 1324 EAMFSITSEYNSGARPCLCDFMGSTELECNT-FGGQ--CPCKPNVIGRTCSACRTGYYGF 1380
++ + S+++ G R C C+ S EC GQ C C+ N G C C +
Sbjct: 256 QSYYYAVSDFSVGGR-CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 1381 P----------NCRPCHCPSTAI-CD----------DNGMCI-CPKNVEGENCDRCKPYT 1418
P C PC+C + C G C C + G +C+RC+
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CY 1476
+++D + C C+C G + LQC+ D+G CAC+ V G CD C+PG ++ + C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 428
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTT 1536
CTCN G+ D CD + +C CK NV G CD C+ FNLQ NP GC+ CFC+G +
Sbjct: 429 PCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 487
Query: 1537 RCSSSYYTWAAIDEMVDWYP-VDVLINNTIELYPHEDVPELT-NVTVLTVGLNDGVTNGK 1594
C +S + + D++ + ++ H P+ + N +L+ + +T
Sbjct: 488 VC-ASTAQFQVHHILSDFHQGAEGWWARSVGGSEHS--PQWSPNGVLLSPEDEEELT--- 541
Query: 1595 VAYFGAPEYYLGKRLTSYGGYLTYTVHYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPP 1654
AP +LG + SYG L T GD + G L H+S+ P
Sbjct: 542 -----APGKFLGDQRFSYGQPLILTFRVPP-GDSPLPVQLRLEGTGLALSLRHSSLSGPQ 595
Query: 1655 VGMPWTHS-VKLSEEEFSTLDGAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVL 1713
++ +E S P+ F L N++ L +R S S + V
Sbjct: 596 DARASQGGRAQVPLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGP-----SPAGPVF 650
Query: 1714 EIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYR-LPSG----FCVPCQCN 1768
V + A+ VE C CP Y G CE CA G+ R +P G CVPC CN
Sbjct: 651 LTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN 710
Query: 1769 GHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFAL 1828
H CD NTGIC+ C+ +T G CE C+ G++G+ G DC C CP +
Sbjct: 711 QHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSA 762
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP 1888
+ E+G ++ +C PG G RCE C G++G P H C C CSGN++P
Sbjct: 763 CTTIPESGEVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCSGNVDPNAV 821
Query: 1889 GSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK---NCTACICDEFGMAD----CD 1941
G+CD ++G CL+C++NT G C C GFYG A+ + C C C G CD
Sbjct: 822 GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCD 881
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKG 2000
TG C C P V C RC P + L G GC C C + S+ QC GQC C G
Sbjct: 882 PVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPG 941
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERW 2060
VTG+ CD+C GF+ + GC C C+ + C+ G C C PG G KCDRC +
Sbjct: 942 VTGQACDRCQLGFFGSSIKGCRACRCSPLGAASAQCHYNGTCVCRPGFEGYKCDRCHYNF 1001
Query: 2061 VLIPQ-EGCLECDSC 2074
L C +C SC
Sbjct: 1002 FLTADGTHCQQCPSC 1016
Score = 275 bits (675), Expect = 2e-72
Identities = 148/436 (33%), Positives = 218/436 (50%), Gaps = 43/436 (9%)
Query: 34 CDICDANNEAKKHPPEYAVD----DRRTWWQSPPLSRGMKY-NEVNLTIDLGQEFHVAYV 88
C CDA + + H Y D D TWWQSP ++ G++Y VN+T+ LG+ + + YV
Sbjct: 74 CQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYV 133
Query: 89 FVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVI 145
+K S RPE + + K + ++P+Q++S S C++ +G+ + L+P +
Sbjct: 134 RLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQKTYGRPEGQYLRPGEDERVAF 189
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C++E+S I PL G + S L RPS+ + S LQEW +T + + L R +
Sbjct: 190 CTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF 249
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
+DP V + Y+Y++ D S+GGRC CNGHA C P D AG L CRCQHNT G C
Sbjct: 250 ----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGP-DVAGQL---ACRCQHNTTGTDC 301
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
+C F+ + W C PCNC + ECT+D E+ G GG+C
Sbjct: 302 ERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS------TGH---GGRC 352
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
+C+ +T G +C +C+ +Y WD CQPC C S +++G C C+P
Sbjct: 353 HHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTV 407
Query: 386 QPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PCTCN G+ + C P G CPCK N G C+ C G
Sbjct: 408 TGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGT 466
Query: 444 YSPE------CKNCEC 453
++ + C +C C
Sbjct: 467 FNLQPHNPAGCSSCFC 482
Score = 184 bits (449), Expect = 4e-45
Identities = 113/369 (30%), Positives = 164/369 (44%), Gaps = 58/369 (15%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+C C G C C G++++ + Q SC PC C+ H T C DP
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKRE---MPQGGPYASCVPCTCNQHGT-C--DPNT------ 719
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFSTGN 371
G C+ C H+TEG +C +C P +Y P+ + D+ CQPC C P S
Sbjct: 720 ----------GICV-CSHHTEGPSCERCLPGFYGNPFAGQADD---CQPCPC-PGQSACT 764
Query: 372 CEEESGR--C-ECRPEFQPPDCSSCAYGYFDYP--------NCKPCTC--NLNGTEGEHC 418
ESG C C P + C C G+F P C C C N++ +C
Sbjct: 765 TIPESGEVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNC 824
Query: 419 TPTDGLC-PCKYNYAGKSCEICEDGYY--------SPECKNCECNTVGSVS--YVCDKLT 467
P G C C +N G CE C++G+Y + +C C C+ GSVS CD +T
Sbjct: 825 DPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVT 884
Query: 468 GDCTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
G C+C + R C++C G+++ C+ C C G++ C +GQC C+ G G
Sbjct: 885 GQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTG 944
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
CD+C G++ + + C C C P G+ S C +G C C F G +CD+C +
Sbjct: 945 QACDRCQLGFFGSSI---KGCRACRCSPLGAASAQCHYNGTCVCRPGFEGYKCDRCHYNF 1001
Query: 585 YKYPDCLSC 593
+ D C
Sbjct: 1002 FLTADGTHC 1010
Score = 178 bits (433), Expect = 4e-43
Identities = 107/350 (30%), Positives = 149/350 (42%), Gaps = 48/350 (13%)
Query: 327 NCQHNTEGINCNKCRPTYYR--PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPE 384
+C G C C P Y R P G + C PC C+ H G C+ +G C C
Sbjct: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCNQH---GTCDPNTGICVCSHH 727
Query: 385 FQPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGEHCTPTDG--LCP-CKYNYAGKS 435
+ P C C G++ P +C+PC C G P G +C C G+
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCP--GQSACTTIPESGEVVCTHCPPGQRGRR 785
Query: 436 CEICEDGYYS--------PE-CKNCECNTVGSVSYV--CDKLTGDCT-CKSKYSGRTCNQ 483
CE+C+DG++ P+ C C+C+ + V CD L+G C C +G C
Sbjct: 786 CEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
Query: 484 CQAGYYNYPT-------CKPCNCDTSGT--EPSICDDVSGQCICKAGFGGPRCDQCLSGY 534
CQ G+Y C PC+C G+ E CD V+GQC C C +C G+
Sbjct: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY--KYPDCL 591
+ GR C C C P GS C G+C C G CD+C G++ C
Sbjct: 906 FDLQPGRG--CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGSSIKGCR 963
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY---NYPACEEC 638
+C C G+ + C NG C C+ F+G KCD C F+ + C++C
Sbjct: 964 ACRCSPLGAASAQCHYNGTCVCRPGFEGYKCDRCHYNFFLTADGTHCQQC 1013
Score = 172 bits (419), Expect = 2e-41
Identities = 111/345 (32%), Positives = 155/345 (44%), Gaps = 48/345 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C+C + Y+G+ C C GY Y +C PC C+ GT CD +G C+C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNCDPTGSTSTSCSADGK--C-NCLTNFGGAQCD 578
GP C++CL G+Y G+ C PC C P S T+ G+ C +C G +C+
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPC-PGQSACTTIPESGEVVCTHCPPGQRGRRCE 787
Query: 579 QCSPGYYKYP--------DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCR 626
C G++ P C C C +V + CD +G C C N G C+ C+
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Query: 627 EQFYNY-----PA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
E FY PA C C+C P+G + C V G+ C C V R C+ C P +
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV-TGQ-CSCLPHVTARDCSRCYPGF 905
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
++LQ GC C C+ G+ C+ K+GQC C+ V + CD+C GF+ +
Sbjct: 906 FDLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFF---GSS 958
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
+ GC C C G+ C G C C EG +CD R HY
Sbjct: 959 IKGCRACRCSPLGAASAQC-HYNGTCVCRPGFEGYKCD---RCHY 999
Score = 167 bits (407), Expect = 5e-40
Identities = 108/352 (30%), Positives = 151/352 (42%), Gaps = 48/352 (13%)
Query: 379 CECRPEFQPPDCSSCAYGY-------FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
C C + C SCA GY Y +C PCTCN +GT C P G+C C ++
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQ 483
G SCE C G+Y + +C+ C C + + + + CT C GR C
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESGEVVCTHCPPGQRGRRCEV 788
Query: 484 CQAGYYNYPT-----CKPCN-CDTSG-TEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
C G++ P +PC+ C SG +P+ CD +SG C+ C G C+ C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 848
Query: 533 GYYMQVLGRE--RQCVPCNCDPTGSTSTSCSAD---GKCNCLTNFGGAQCDQCSPGYYKY 587
G+Y L +C+PC+C P GS S D G+C+CL + C +C PG++
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDL 908
Query: 588 P---DCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQFY--NYPACEECNCD 641
C SC C GS C G C C+ G CD C+ F+ + C C C
Sbjct: 909 QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGSSIKGCRACRCS 968
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
P G A+ A C C C+ +G C+ C Y + C+QC
Sbjct: 969 PLG--AASAQC---HYNGTCVCRPGFEGYKCDRCH--YNFFLTADGTHCQQC 1013
Score = 163 bits (397), Expect = 8e-39
Identities = 96/339 (28%), Positives = 145/339 (42%), Gaps = 50/339 (14%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H TC+P N +C C H+T GP C +C GF + + C+P
Sbjct: 707 CTCNQHG-TCDP-------NTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQP 754
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + CT PE G C +C G C C ++
Sbjct: 755 CPCPGQSA-CTTIPE--------------SGEVVCTHCPPGQRGRRCEVCDDGFFGDPLG 799
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP---- 401
+ C CQC DP+ + GNC+ SG C C C C G++
Sbjct: 800 LFGHPQPCHQCQCSGNVDPN-AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR 858
Query: 402 ---NCKPCTCNLNGTEGEH--CTPTDGLCPCKYNYAGKSCEICEDGYYSPE----CKNCE 452
C PC+C+ G+ E C P G C C + + C C G++ + C++C+
Sbjct: 859 PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCK 918
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY--NYPTCKPCNCDTSGTEPSICD 510
C+ +GS C TG CTC+ +G+ C++CQ G++ + C+ C C G + C
Sbjct: 919 CHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGSSIKGCRACRCSPLGAASAQC- 977
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRE-RQCVPC 548
+G C+C+ GF G +CD+C +++ G +QC C
Sbjct: 978 HYNGTCVCRPGFEGYKCDRCHYNFFLTADGTHCQQCPSC 1016
Score = 138 bits (335), Expect = 3e-31
Identities = 99/358 (27%), Positives = 143/358 (39%), Gaps = 51/358 (14%)
Query: 424 LCPCKYNYAGKSCEICEDGY--YSPE------CKNCECNTVGSVSYVCDKLTGDCTCKSK 475
+C C Y G+ CE C GY P+ C C CN G+ CD TG C C
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHH 727
Query: 476 YSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD 528
G +C +C G+Y P C+PC C +I + C C G G RC+
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESGEVVCTHCPPGQRGRRCE 787
Query: 529 QCLSGYY---MQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCS 581
C G++ + + G + C C C + + D G C CL N G C+ C
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Query: 582 PGYY-------KYPDCLSCNCDVSGSIGS--TCDD-NGLCHCKSNFDGAKCDTCREQFYN 631
G+Y C+ C+C GS+ CD G C C + C C F++
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
Query: 632 YP---ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
C C C P G + C P C C+ V G+ C+ C+ ++ +
Sbjct: 908 LQPGRGCRSCKCHPLG--SQEDQCH--PKTGQCTCRPGVTGQACDRCQLGFFG---SSIK 960
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
GC C C+ G ++ C+ +G CVC+ +CD+C F+ T D C +C
Sbjct: 961 GCRACRCSPLGAASA--QCH-YNGTCVCRPGFEGYKCDRCHYNFF--LTADGTHCQQC 1013
Score = 129 bits (312), Expect = 2e-28
Identities = 70/217 (32%), Positives = 99/217 (45%), Gaps = 25/217 (11%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGR-----ERQCVPCNCD 551
C +G DV+GQ C C+ G C++CL + + R +C+PCNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 552 PTGSTST-------SCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGS 600
T S G+C+ C + G C++C +Y + C C+C +GS
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGS 390
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRGVTASFAGCGSVPAG 658
+ CDD G C CK G KCD C F++ C C C+P G S C P
Sbjct: 391 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG---SLDTCD--PRS 445
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C CK+ V+G +C+ C+P +NLQ +NP GC C C
Sbjct: 446 GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 116 bits (279), Expect = 2e-24
Identities = 64/201 (31%), Positives = 84/201 (41%), Gaps = 21/201 (10%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSACRTGYYGFP-------NCRPCHC-PSTAI-----CDD- 1396
C+ G C C N G C C+ G+YG C PC C P ++ CD
Sbjct: 824 CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV 883
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
G C C +V +C RC P F+ RGC C C+PLG + QC +G+C CR
Sbjct: 884 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG--SQEDQCHPKTGQCTCRPG 941
Query: 1457 VRGRVCDHCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
V G+ CD C G + + C C C+ G C N C C+ G CD C
Sbjct: 942 VTGQACDRCQLGFFGSSIKGCRACRCSPLGAASAQCHYN-GTCVCRPGFEGYKCDRCHYN 1000
Query: 1515 YFNLQD-DNPDGCTKCFCFGK 1534
+F D + C C+ K
Sbjct: 1001 FFLTADGTHCQQCPSCYALVK 1021
Score = 113 bits (273), Expect = 9e-24
Identities = 68/227 (29%), Positives = 94/227 (41%), Gaps = 34/227 (14%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P++ G CQHNT G +C +C P + RP+
Sbjct: 271 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERCLPFFQDRPWA 314
Query: 350 KRWDEL-DVCQPCQCDPHFSTGNCEEE-------SGRCE-CRPEFQPPDCSSCAYGYFDY 400
+ E C PC C + E GRC CR P C C ++ +
Sbjct: 315 RGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW 374
Query: 401 -PN--CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE---CKNCECN 454
P C+PC C G+ C T G C CK G C+ C G++S C+ C CN
Sbjct: 375 DPRMPCQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN 433
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
GS+ CD +G C CK G C++C+ G +N P C +
Sbjct: 434 PAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
Score = 110 bits (264), Expect = 1e-22
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 33/223 (14%)
Query: 548 CNCDPTGST-STSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S + C C N G C++C P + P +CL CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 597 -------VSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGV 645
+ + G CH C+ + G C+ C+E FY++ C+ C+C G
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAG- 389
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
+ C C CK V G C+ C P + +L E GC C CN AG+L++
Sbjct: 390 -SLHLQCDDTGT---CACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-- 440
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C+ +SG+C CK++V CD+C G + LQ ++ GC+ C C
Sbjct: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 108 bits (259), Expect = 4e-22
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 30/257 (11%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC----EDG 442
P S Y D+ C CN + +E C C++N G CE C +D
Sbjct: 252 PKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 443 YYSP-------ECKNCECN------TVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGY 488
++ EC C C+ T + G C C+ +G C +CQ +
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 489 YNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
Y++ C+PC+C ++G+ CDD +G C CK G +CD+CL G++ E C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSL---SEGGC 427
Query: 546 VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDVSGS 600
PC C+P GS T G+C C N G CD+C PG + C SC C
Sbjct: 428 RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSK 487
Query: 601 IGSTCDDNGLCHCKSNF 617
+ ++ + H S+F
Sbjct: 488 VCASTAQFQVHHILSDF 504
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 593 CNCDVSGS-IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C C+ S G C C+ N G C+ C F + P C CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 642 PRGVTASFAG--CGSVPAGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA 698
R +F S G C C+D G C C+ +++ P C+ C+C A
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSA 388
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
G+L+ C+ +G C CK V +CD+CL GF+ L GC C C+ GS+D C
Sbjct: 389 GSLHL--QCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-C 441
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D +G+C C VEG CD+
Sbjct: 442 DPRSGRCPCKENVEGNLCDR 461
Score = 83.8 bits (198), Expect = 1e-14
Identities = 39/113 (34%), Positives = 56/113 (49%), Gaps = 9/113 (7%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
+++ + C F + + G R C C +GS E +C+ GQC C+P V G+ C
Sbjct: 892 HVTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 949
Query: 1373 CRTGYYG--FPNCRPCHC----PSTAICDDNGMCICPKNVEGENCDRCKPYTF 1419
C+ G++G CR C C ++A C NG C+C EG CDRC Y F
Sbjct: 950 CQLGFFGSSIKGCRACRCSPLGAASAQCHYNGTCVCRPGFEGYKCDRCH-YNF 1001
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLY-WNLQEYNPF-GCEQCNCNLAGTLNSLGACNTKSGQCVC 716
E+C C G+ C C P Y + + P+ C C CN GT C+ +G CVC
Sbjct: 671 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 724
Query: 717 KQHVGERQCDQCLDGFY-RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGR 774
H C++CL GFY C C C + + C HC GR
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESGEVVCTHCPPGQRGR 784
Query: 775 RCD 777
RC+
Sbjct: 785 RCE 787
Score = 56.0 bits (129), Expect = 2e-06
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 1316 PNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
P TG C + S G RPC C+ GS + C+ G+CPCK NV G C CR
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
Query: 1375 TGYYGFPNCRPCHCPSTAICDDNGMC 1400
G + P C S + +C
Sbjct: 464 PGTFNLQPHNPAGCSSCFCYGHSKVC 489
>BC033663-1|AAH33663.1| 401|Homo sapiens Unknown (protein for
IMAGE:4449486) protein.
Length = 401
Score = 383 bits (942), Expect = e-105
Identities = 169/355 (47%), Positives = 225/355 (63%), Gaps = 27/355 (7%)
Query: 117 QYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
QYF+ S DC + FG+E+ +T+DD V+C TEYS+IVPLE+GE+ +SL+N RP + +
Sbjct: 4 QYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFT 63
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S L+E+T+ATN+RLR LRT LLGHL+S A++DPTVTRRY+YSIKDISIGG+C+CNGH
Sbjct: 64 FSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGH 123
Query: 237 ADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH 296
A+ C +P + C CQH+TCG C++CC+G+ Q++WR + CE CNCH H
Sbjct: 124 AEVCNINNPE---KLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGH 180
Query: 297 TTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELD 356
+ C YDP+++ ++ SL+ G Y GGG C+NCQHNT G+NC +C YYRPYG D D
Sbjct: 181 ASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPD 240
Query: 357 VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC------------- 403
C PC CDP + G CE+ SGRC C+P F +C CA GY+++P C
Sbjct: 241 GCIPCSCDPEHADG-CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSS 299
Query: 404 --------KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS-PECK 449
K C CNL G E C G C C+ G C+ C G+YS P C+
Sbjct: 300 EDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVEGPRCDTCRSGFYSFPICQ 353
Score = 109 bits (261), Expect = 2e-22
Identities = 68/237 (28%), Positives = 99/237 (41%), Gaps = 52/237 (21%)
Query: 451 CECNTVGSVSYVCD-KLTGDCTCKSKYSGRTCNQCQAGYYNY---PT-------CKPCNC 499
C CN V + + + C C+ G TC++C GY P C+ CNC
Sbjct: 118 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 177
Query: 500 DTSGTEPSICDDVS---------------GQCI-CKAGFGGPRCDQCLSGYYMQV---LG 540
+ DV G CI C+ G C+QC GYY +
Sbjct: 178 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 237
Query: 541 RERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL--------- 591
C+PC+CDP + G+C+C NF G C++C+ GYY +P CL
Sbjct: 238 APDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVST 296
Query: 592 ------------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE 636
C+C++ G + CD +G C C+ +G +CDTCR FY++P C+
Sbjct: 297 PSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQ 353
Score = 103 bits (247), Expect = 1e-20
Identities = 76/243 (31%), Positives = 107/243 (44%), Gaps = 70/243 (28%)
Query: 328 CQHNTEGINCNKCRPTY----YRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
CQH+T G C++C Y +RP W++ C+ C C H S NC
Sbjct: 140 CQHHTCGETCDRCCTGYNQRRWRPAA--WEQSHECEACNCHGHAS--NC----------- 184
Query: 384 EFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDG 442
Y+D P+ + +LN T+G + G+C C++N AG +CE C G
Sbjct: 185 -------------YYD-PDVERQQASLN-TQGIYAG--GGVCINCQHNTAGVNCEQCAKG 227
Query: 443 YYSPE---------CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT 493
YY P C C C+ + C++ +G C CK + G C +C GYYN+P
Sbjct: 228 YYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPF 285
Query: 494 C---------------------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
C K C+C+ G P IC D G+C+C+ G GPRCD C S
Sbjct: 286 CLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC-DAHGRCLCRPGVEGPRCDTCRS 344
Query: 533 GYY 535
G+Y
Sbjct: 345 GFY 347
Score = 95.5 bits (227), Expect = 3e-18
Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 36/229 (15%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGN 1882
N A C+++ L C CQ G C+ C GY C+ CNC G+
Sbjct: 121 NGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGH 180
Query: 1883 IN-----PQDPGSCDSIN--------GDCLKCVNNTAGAACNLCAPGFY---GDAIFSKN 1926
+ P S+N G C+ C +NTAG C CA G+Y G + + +
Sbjct: 181 ASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPD 240
Query: 1927 -CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLG------CTP--- 1976
C C CD C+ +G C C+P G+ C++CA ++ L TP
Sbjct: 241 GCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 300
Query: 1977 ---------CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
C+C + + D +G+C C GV G +CD C +GF+++
Sbjct: 301 DPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSF 349
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/233 (30%), Positives = 99/233 (42%), Gaps = 44/233 (18%)
Query: 1765 CQCNGHSDQCDVNTGICL---NCADNTIGDHCEFCMSGYH----GDATVGTPRDCLICAC 1817
C CNGH++ C++N L C +T G+ C+ C +GY+ A +C C C
Sbjct: 118 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 177
Query: 1818 PMPYPSNNF----------ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTD 1867
+ SN + +L+ G + NCQ G CE CA GYY P
Sbjct: 178 -HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVP 235
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG------DA 1921
+ D C PC+C +P+ C+ +G C C N G C CA G+Y
Sbjct: 236 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIP 290
Query: 1922 IF-----------SKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRC 1961
IF + + C C+ G+ CD+ G C+CRPGV G +CD C
Sbjct: 291 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGPRCDTC 342
Score = 87.4 bits (207), Expect = 9e-16
Identities = 68/224 (30%), Positives = 94/224 (41%), Gaps = 55/224 (24%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRL---PSGF-----CVPCQCNGHSDQC-----------DV 1776
C+C G +C++C G+ + P+ + C C C+GH+ C +
Sbjct: 138 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 197
Query: 1777 NT-------GICLNCADNTIGDHCEFCMSGYHG--DATVGTPRDCLICACPMPYPSNNFA 1827
NT G+C+NC NT G +CE C GY+ V P C+ C+C +
Sbjct: 198 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH------ 251
Query: 1828 LSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGI-------------PEDTDLHTGDYC 1874
D E GS C+C+P + G CE CA GYY P D GD
Sbjct: 252 --ADGCEQGS-GRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD-I 307
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFY 1918
K C+C N+ P CD+ +G CL C G C+ C GFY
Sbjct: 308 KGCDC--NLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFY 347
Score = 86.2 bits (204), Expect = 2e-15
Identities = 47/147 (31%), Positives = 67/147 (45%), Gaps = 32/147 (21%)
Query: 1398 GMCI-CPKNVEGENCDRC-----KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
G+CI C N G NC++C +PY D GC C+C+P G CE SG+C
Sbjct: 207 GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG----CEQGSGRC 262
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQ---------------------CTCNRHGTTYDVC 1490
C+ N G C+ C G+Y FP C + C CN G ++C
Sbjct: 263 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC 322
Query: 1491 DQNTAQCYCKTNVRGQACDTCKEEYFN 1517
D + +C C+ V G CDTC+ +++
Sbjct: 323 DAH-GRCLCRPGVEGPRCDTCRSGFYS 348
Score = 80.6 bits (190), Expect = 1e-13
Identities = 63/214 (29%), Positives = 92/214 (42%), Gaps = 49/214 (22%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQ-----VLGRERQCVPCNC---------DPT-----GS 555
+C C+ G CD+C +GY + + +C CNC DP S
Sbjct: 137 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 196
Query: 556 TSTS--CSADGKC-NCLTNFGGAQCDQCSPGYYK-------YPD-CLSCNCDVSGSIGST 604
+T + G C NC N G C+QC+ GYY+ PD C+ C+CD + G
Sbjct: 197 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-- 254
Query: 605 CDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTAS-------FAGC---- 652
C+ +G CHCK NF G C+ C +YN+P C P +S GC
Sbjct: 255 CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNL 314
Query: 653 -GSVP----AGELCQCKDRVQGRICNDCKPLYWN 681
G +P A C C+ V+G C+ C+ +++
Sbjct: 315 EGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYS 348
Score = 79.4 bits (187), Expect = 2e-13
Identities = 50/146 (34%), Positives = 71/146 (48%), Gaps = 27/146 (18%)
Query: 1738 CPRAYRGLSCEQCAEGHYR-------LPSGFCVPCQCNG-HSDQCDVNTGICLNCADNTI 1789
C G++CEQCA+G+YR P G C+PC C+ H+D C+ +G C +C N
Sbjct: 212 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDG-CIPCSCDPEHADGCEQGSGRC-HCKPNFH 269
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS-----CDLSENGSLIS---- 1840
GD+CE C GY+ P I P+ PS+ ++ CD + G L
Sbjct: 270 GDNCEKCAIGYYN-----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 324
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIP 1863
C C+PG G RC+ C +G+Y P
Sbjct: 325 HGRCLCRPGVEGPRCDTCRSGFYSFP 350
Score = 70.5 bits (165), Expect = 1e-10
Identities = 52/150 (34%), Positives = 64/150 (42%), Gaps = 33/150 (22%)
Query: 1356 GGQC-PCKPNVIGRTCSACRTGYY---GFP-----NCRPCHC-PSTAI-CDD-NGMCICP 1403
GG C C+ N G C C GYY G P C PC C P A C+ +G C C
Sbjct: 206 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCK 265
Query: 1404 KNVEGENCDRCKPYTFNF------------------DVQRGCDDCNCNPLGVVGNQLQCE 1445
N G+NC++C +NF V C+CN GV+ C+
Sbjct: 266 PNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPE--ICD 323
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDC 1475
A G+C CR V G CD C G Y+FP C
Sbjct: 324 A-HGRCLCRPGVEGPRCDTCRSGFYSFPIC 352
Score = 70.1 bits (164), Expect = 1e-10
Identities = 40/145 (27%), Positives = 65/145 (44%), Gaps = 26/145 (17%)
Query: 1945 GTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCGIASESTQCDDDNGQCRCA 1998
G C+ C+ G C++CA ++ ++ GC PC+C + C+ +G+C C
Sbjct: 207 GVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCD-PEHADGCEQGSGRCHCK 265
Query: 1999 KGVTGKQCDQCAAGFWNY------------TKDGCD-------HCNCNTGYSVGFMCNAT 2039
G C++CA G++N+ T D C+CN + +C+A
Sbjct: 266 PNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH 325
Query: 2040 GQCECLPGVIGEKCDRCPERWVLIP 2064
G+C C PGV G +CD C + P
Sbjct: 326 GRCLCRPGVEGPRCDTCRSGFYSFP 350
Score = 62.9 bits (146), Expect = 2e-08
Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 32/169 (18%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPY 1417
+C C+ + G TC C TGY RP + C+ C C + NC
Sbjct: 137 RCECQHHTCGETCDRCCTGY-NQRRWRPAAWEQSHECE---ACNC--HGHASNC------ 184
Query: 1418 TFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYA----- 1471
++ DV+R + N G+ A G C C+ N G C+ C G+Y
Sbjct: 185 YYDPDVER--QQASLNTQGIY-------AGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP 235
Query: 1472 --FPD-CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFN 1517
PD C C+C+ D C+Q + +C+CK N G C+ C Y+N
Sbjct: 236 VDAPDGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYN 282
Score = 62.1 bits (144), Expect = 4e-08
Identities = 38/125 (30%), Positives = 51/125 (40%), Gaps = 27/125 (21%)
Query: 1327 FSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCR-- 1384
+ + + G PC CD + C G+C CKPN G C C GYY FP C
Sbjct: 232 YGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRI 289
Query: 1385 ---PCHCPST--------------------AICDDNGMCICPKNVEGENCDRCKPYTFNF 1421
P PS+ ICD +G C+C VEG CD C+ ++F
Sbjct: 290 PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSF 349
Query: 1422 DVQRG 1426
+ +G
Sbjct: 350 PICQG 354
Score = 58.4 bits (135), Expect = 5e-07
Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 46/208 (22%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY---PA-------CEECNC-----------DPRGVTASF 649
C C+ + G CD C + PA CE CNC D AS
Sbjct: 138 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 197
Query: 650 AGCGSVPAGELC-QCKDRVQGRICNDCKPLYWN---LQEYNPFGCEQCNCNLAGTLNSLG 705
G G +C C+ G C C Y+ + P GC C+C+
Sbjct: 198 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDP----EHAD 253
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRL---------------QTNDVFGCTE-CDCD 749
C SG+C CK + C++C G+Y + V G + CDC+
Sbjct: 254 GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN 313
Query: 750 IGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ G + CD G+C C VEG RCD
Sbjct: 314 LEGVLPEICD-AHGRCLCRPGVEGPRCD 340
Score = 56.4 bits (130), Expect = 2e-06
Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 29/151 (19%)
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFG------CEQCNCN--------------LAGT 700
C+C+ G C+ C Y N + + P CE CNC+ +
Sbjct: 138 CECQHHTCGETCDRCCTGY-NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 196
Query: 701 LNSLGACNTKSGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDN 756
LN+ G G C+ C+ + C+QC G+YR + + GC C CD + +
Sbjct: 197 LNTQGIY-AGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHA--D 253
Query: 757 NCDKTTGQCHCHSRVEGRRCDQPIRAHY-FP 786
C++ +G+CHC G C++ +Y FP
Sbjct: 254 GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFP 284
>BC113455-1|AAI13456.1| 1786|Homo sapiens laminin, beta 1 protein.
Length = 1786
Score = 334 bits (821), Expect = 3e-90
Identities = 167/479 (34%), Positives = 243/479 (50%), Gaps = 30/479 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C + C++C GH+ PS C PCQCNGH+D CD TG CLNC D T+G +CE
Sbjct: 839 QCHCFQGVYARQCDRCLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 1795 FCMSGYHGDATVGTPRDCLICACP-MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++GY+GD +G+ C C CP P FA SC ++C C PGY G+RC+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA+GY+G P + G C+PC C NI+ DP +CD G CLKC+ +T G C C
Sbjct: 957 DCASGYFGNPSE----VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
Query: 1914 APGFYGDAIFSKNCTACICDEFGM---------ADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
G+YGDA+ ++C C+C+ G CD TG C+C P VIG+ CDRCAP+
Sbjct: 1013 RFGYYGDAL-QQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 1965 HWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH 2023
W L +G GC PCNC A S C++ GQC+C G G+ C +C FW C
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRA 1131
Query: 2024 CNCN-TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSV 2082
C+C+ G +TGQC C+ GV G +CD+C + + + C C C F++
Sbjct: 1132 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD-CTPCHQC-----FAL 1185
Query: 2083 ED-LSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTV----DIGEVTSS 2137
D + A L N T F +KA + + + + + KV+++K + E +
Sbjct: 1186 WDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKN 1245
Query: 2138 IKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVAD 2196
I L A+ L++ + ++S + + L +++ A VK +A+
Sbjct: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAE 1304
Score = 241 bits (591), Expect = 3e-62
Identities = 137/466 (29%), Positives = 230/466 (49%), Gaps = 46/466 (9%)
Query: 50 YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDY 109
+A + + WWQS G++ V + +DL EFH ++ + + RP ++E+S+D+
Sbjct: 103 FAPNRLKIWWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTF-KTFRPAAMLIERSSDF 156
Query: 110 GKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR 169
GKT+ ++YF+ DCE F S P+ K D +IC + YS I P +GE+ L+
Sbjct: 157 GKTWGVYRYFA---YDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPA 213
Query: 170 PSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGG 229
++ + Q + TN+R++ ++ L +L+ +R + + +Y+Y++ D+ + G
Sbjct: 214 FKIEDPYSPRI-QNLLKITNLRIKFVKLHTLGDNLLD-SRME--IREKYYYAVYDMVVRG 269
Query: 230 RCMCNGHADTCEPADPAGN-LNILV---CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
C C GHA C P D + +V C C+HNT G C C + WR ++ +
Sbjct: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
+C+ CNC+ H+ C +D +++ + GG C +CQHNT G NC +C+P YY
Sbjct: 330 NACKKCNCNEHSISCHFD-------MAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYY 382
Query: 346 RPYGKRWDELDVCQPCQCDPHFS--TGNCEEE--------SGRCECRPEFQPPDCSSCAY 395
+ + + + C+ C CDP S G C+ +G+C C+ + C C
Sbjct: 383 QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKE 442
Query: 396 GYFDYPN-----CKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--- 445
G++D + CK C CN GT G C G C CK G+ C+ C ++
Sbjct: 443 GFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSN 502
Query: 446 --PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
C+ C+C+ G+++ C +G C+C+ GR CN+ + GYY
Sbjct: 503 DLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 239 bits (585), Expect = 1e-61
Identities = 137/408 (33%), Positives = 195/408 (47%), Gaps = 41/408 (10%)
Query: 406 CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--PE-CKNCECNTVGSVSYV 462
C C+ G+ C P G C C+ N G++C C G + P CK CEC+ GSV+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 463 CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
C+ +TG C C R C++C G++ +P+C+PC C+ + CD V+G+C+ C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADD---CDPVTGECLNCQDY 889
Query: 522 FGGPRCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTS-----TSCSADG-----KCNCLT 570
G C++CL+GYY ++G C PC C P G S SC D C C
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDP 948
Query: 571 NFGGAQCDQCSPGYYKYP-----DCLSCNC--DVSGSIGSTCD-DNGLC-HCKSNFDGAK 621
+ G++CD C+ GY+ P C C C ++ + CD + G C C + +G
Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 622 CDTCREQFYN---YPACEECNCDPRGVT---ASFAGCGSVPAGELCQCKDRVQGRICNDC 675
C CR +Y C +C C+ G + + C A C C V G+ C+ C
Sbjct: 1009 CQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRC 1068
Query: 676 KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRL 735
P W L + GC+ CNCN A + +CN +GQC C G R C +C + F+
Sbjct: 1069 APNTWQLA--SGTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFW-- 1122
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
DV C CDCD G CD++TGQC C VEG RCD+ R +
Sbjct: 1123 GDPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY 1169
Score = 227 bits (555), Expect = 6e-58
Identities = 140/424 (33%), Positives = 191/424 (45%), Gaps = 55/424 (12%)
Query: 361 CQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEH 417
C+CDP S + C+ G+C+CRP C+ CA G F + CKPC C+L G+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
C P G C C + C+ C G++ P C+ C+CN G CD +TG+C C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN--GHAD-DCDPVTGECLNCQDY 889
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNC----DTSGTEPSIC--DDVSGQ--CICKAG 521
G C +C AGYY P C+PC C D+ C D V+ Q C+C G
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 949
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQC 577
+ G RCD C SGY+ C PC C T+ + D G+C CL + G C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 578 DQCSPGYY---KYPDCLSCNCDVSGSI-----GSTCD---DNGLCHCKSNFDGAKCDTCR 626
C GYY DC C C+ G++ GS C G C C N G CD C
Sbjct: 1010 QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 627 E---QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
Q + C+ CNC+ SF + G+ CQC GR C++C+ L+W
Sbjct: 1070 PNTWQLASGTGCDPCNCN---AAHSFGPSCNEFTGQ-CQCMPGFGGRTCSECQELFWGDP 1125
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVF-G 742
+ C C+C+ G C+ +GQCVC + V +CD+C G+ + VF
Sbjct: 1126 DVE---CRACDCDPRGI--ETPQCDQSTGQCVCVEGVEGPRCDKCTRGY-----SGVFPD 1175
Query: 743 CTEC 746
CT C
Sbjct: 1176 CTPC 1179
Score = 202 bits (494), Expect = 1e-50
Identities = 129/414 (31%), Positives = 186/414 (44%), Gaps = 62/414 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRP-TY-YRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGR 378
GG+C C+ N G CN+C P T+ + P G C+PC+C S C +G+
Sbjct: 789 GGQC-QCRPNVVGRTCNRCAPGTFGFGPSG--------CKPCECHLQGSVNAFCNPVTGQ 839
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCE 437
C C C C G++ +P+C+PC CN + C P G C C+ G +CE
Sbjct: 840 CHCFQGVYARQCDRCLPGHWGFPSCQPCQCN---GHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 438 ICEDGYY-------SPECKNCEC----NTVGSVSYVC--DKLTGD--CTCKSKYSGRTCN 482
C GYY C+ C C ++ + C D +T C C Y G C+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 483 QCQAGYYNYP-----TCKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGY 534
C +GY+ P +C+PC C + T+P CD +G+C+ C G C C GY
Sbjct: 957 DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCS--------ADGKCNCLTNFGGAQCDQCSPGYYK 586
Y L ++ C C C+ G+ C+ A G+C CL N G CD+C+P ++
Sbjct: 1017 YGDAL--QQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ 1074
Query: 587 YPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
C CNC+ + S G +C++ G C C F G C C+E F+ P C C+C
Sbjct: 1075 LASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDC 1134
Query: 641 DPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL-QEYNPFGCEQC 693
DPRG+ C G+ C C + V+G C+ C Y + + P C QC
Sbjct: 1135 DPRGIET--PQCDQ-STGQ-CVCVEGVEGPRCDKCTRGYSGVFPDCTP--CHQC 1182
Score = 180 bits (439), Expect = 7e-44
Identities = 124/364 (34%), Positives = 159/364 (43%), Gaps = 47/364 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL-PSGFCVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+CQC G +C +CA G + PSG C PC+C+ C+ TG C +C
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQC-HCFQGVYA 848
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C+ G+ G + C C C N A CD L NCQ G
Sbjct: 849 RQCDRCLPGHWGFPS------CQPCQC------NGHADDCDPVTGECL---NCQDYTMGH 893
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSC--DSINGDCLKCVNNTA 1906
CE C AGYYG D + +GD+C+PC C + Q SC D + L CV +
Sbjct: 894 NCERCLAGYYG---DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ-LACVCDPG 949
Query: 1907 --GAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKC 1958
G+ C+ CA G++G+ + +C C C D CD TG C+ C GE C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 1959 DRCAPDHWGLNTGLGCTPCNC---GIASE-----STQCDDDNGQCRCAKGVTGKQCDQCA 2010
C ++G C C C G E QCD GQC C V G+ CD+CA
Sbjct: 1010 QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 2011 AGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC 2068
W GCD CNCN +S G CN TGQC+C+PG G C C E + P C
Sbjct: 1070 PNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVEC 1129
Query: 2069 LECD 2072
CD
Sbjct: 1130 RACD 1133
Score = 180 bits (438), Expect = 9e-44
Identities = 131/472 (27%), Positives = 194/472 (41%), Gaps = 83/472 (17%)
Query: 188 TNVRLRLLRTKNLLGHLMSVARQDPT-VTRRYFYSIKDI--SIGGRCMCNGHADTCEPAD 244
TN + L + SV + T V R +SI + G C C+ D
Sbjct: 727 TNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCD 786
Query: 245 PAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH-------- 296
P G C+C+ N G CN+C G + + C+PC CH
Sbjct: 787 PNGGQ----CQCRPNVVGRTCNRCAPG--------TFGFGPSGCKPCECHLQGSVNAFCN 834
Query: 297 --TTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHN-------------------TEGI 335
T +C + ++ + G + G C CQ N T G
Sbjct: 835 PVTGQCHCFQGVYARQCDRCLPGHW-GFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-----NCEEE----SGRCECRPEFQ 386
NC +C YY D C+PC C +G +C ++ C C P +
Sbjct: 894 NCERCLAGYYG--DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYI 951
Query: 387 PPDCSSCAYGYFDYP-----NCKPCTC--NLNGTEGEHCTPTDGLC-PCKYNYAGKSCEI 438
C CA GYF P +C+PC C N++ T+ E C G C C Y+ G+ C+
Sbjct: 952 GSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 1011
Query: 439 CEDGYY----SPECKNCECNTVGSV-------SYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
C GYY +C+ C CN +G+V CDK TG C C G+ C++C
Sbjct: 1012 CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 488 YYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
+ + C PCNC+ + + C++ +GQC C GFGG C +C ++ + +
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD---PDVE 1128
Query: 545 CVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN 594
C C+CDP G + C + G+C C+ G +CD+C+ GY +PDC C+
Sbjct: 1129 CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCH 1180
Score = 172 bits (419), Expect = 2e-41
Identities = 99/328 (30%), Positives = 155/328 (47%), Gaps = 36/328 (10%)
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC---------DVSGSIGST 604
G C C N G C+ C Y+ P C CNC D++ + +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 605 CDDNGLCH-CKSNFDGAKCDTCREQFYNYPA--------CEECNCDP-----RGVTASFA 650
G+C C+ N G C+ C+ +Y +P CE C CDP G+ S+
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
+ C+CK V+G C+ CK +++L +PFGC+ C CN GT+ C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 711 SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSR 770
+G C CK+ V + CDQCL + L +ND+ GC CDCD+GG+++N+C +GQC C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
Query: 771 VEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSGP--VRYRNSEEVFPEYSWKGYVVFSLL 828
+ GR+C++ +YF TL + YE E+ G V + ++ P ++ G+V
Sbjct: 535 MIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEG 594
Query: 829 QNEVINIIQITKSSLYRMVLKYANPLRD 856
I I S Y ++++Y L D
Sbjct: 595 AYLEFFIDNIPYSMEYDILIRYEPQLPD 622
Score = 147 bits (355), Expect = 1e-33
Identities = 95/287 (33%), Positives = 131/287 (45%), Gaps = 36/287 (12%)
Query: 1765 CQCNGHSDQCDVNTGI-----------CLNCADNTIGDHCEFCMSGYHG----DATVGTP 1809
C C GH+ +C G C+ C NT G +CE CM YH A
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 1810 RDCLICACPMPYPSNNFALSCDLSE-NGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTD 1867
C C C S +F ++ L+ N S C+ CQ G CE C YY PE D
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE-RD 388
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDS--------INGDCLKCVNNTAGAACNLCAPGFYG 1919
+ ++C+ C C Q+ G CDS I G C +C N G C++C GFY
Sbjct: 389 IRDPNFCERCTCDP-AGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYD 446
Query: 1920 DAIFSK-NCTACICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL-G 1973
+ C +C C+ G CDS TG C C+ V G+ CD+C P+HWGL+ L G
Sbjct: 447 LSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDG 506
Query: 1974 CTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD 2019
C PC+C + + C ++GQC C + G+QC++ G++ T D
Sbjct: 507 CRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLD 553
Score = 138 bits (334), Expect = 3e-31
Identities = 91/294 (30%), Positives = 136/294 (46%), Gaps = 57/294 (19%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY----R 346
C C+ H +EC +E ++ G G C+ C+HNT+G+NC C Y+ R
Sbjct: 271 CFCYGHASECAPVDGFNE-----EVEGMVHG--HCM-CRHNTKGLNCELCMDFYHDLPWR 322
Query: 347 PYGKRWDELDVCQPCQCDPH-----------FSTGNCEEESGRCE-CRPEFQPPDCSSCA 394
P R + C+ C C+ H +TGN G C+ C+ +C C
Sbjct: 323 PAEGR--NSNACKKCNCNEHSISCHFDMAVYLATGNVS--GGVCDDCQHNTMGRNCEQCK 378
Query: 395 YGYFDYPN--------CKPCTCNLNGTEGEH-CTP-TD-------GLCPCKYNYAGKSCE 437
Y+ +P C+ CTC+ G++ E C TD G C CK N G+ C+
Sbjct: 379 PFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCD 438
Query: 438 ICEDGYY--SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
+C++G+Y S E CK+C CN +G++ CD TG C CK +G+ C+QC ++
Sbjct: 439 VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHW 498
Query: 490 NYPT----CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
C+PC+CD G + C SGQC C+ G +C++ GYY L
Sbjct: 499 GLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATL 552
Score = 138 bits (333), Expect = 5e-31
Identities = 86/260 (33%), Positives = 119/260 (45%), Gaps = 43/260 (16%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYY----MQVLGRERQ-CVPCNC---------DPTGSTS 557
V G C+C+ G C+ C+ Y+ GR C CNC D +
Sbjct: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
Query: 558 TSCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIG-STCDD 607
T + G C+ C N G C+QC P YY++P+ C C CD +GS CD
Sbjct: 354 TGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
Query: 608 ---------NGLCHCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFAGCG 653
G C CK N +G CD C+E FY+ + C+ C C+P G C
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
S G C CK V G+ C+ C P +W L + GC C+C+L G LN+ +C +SGQ
Sbjct: 474 S-ETGH-CYCKRLVTGQHCDQCLPEHWGLSN-DLDGCRPCDCDLGGALNN--SCFAESGQ 528
Query: 714 CVCKQHVGERQCDQCLDGFY 733
C C+ H+ RQC++ G+Y
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 137 bits (332), Expect = 6e-31
Identities = 83/232 (35%), Positives = 101/232 (43%), Gaps = 27/232 (11%)
Query: 1322 CREAMFSITSEYNSGARPCLC-DFMGSTELE-CNTFGGQC-PCKPNVIGRTCSACRTGYY 1378
C F SE +PC C + + +T+ E C+ G+C C + G C CR GYY
Sbjct: 958 CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
Query: 1379 GFP---NCRPC----------HCP-STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDV 1423
G +CR C HC S CD G C+C NV G+NCDRC P T+
Sbjct: 1018 GDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 1077
Query: 1424 QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCN 1481
GCD CNCN G C +G+C C GR C C + PD C C C+
Sbjct: 1078 GTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCD 1135
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCF-CF 1532
G CDQ+T QC C V G CD C Y + D CT C CF
Sbjct: 1136 PRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD----CTPCHQCF 1183
Score = 132 bits (319), Expect = 2e-29
Identities = 70/205 (34%), Positives = 101/205 (49%), Gaps = 29/205 (14%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASF-----AGC 652
+G C C+ N G C+ C + +++ P AC++CNC+ ++ F
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQE---YNPFGCEQCNCNLAGTLNSLGACNT 709
G+V G C+ GR C CKP Y+ E +P CE+C C+ AG+ N G C++
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE-GICDS 413
Query: 710 K--------SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSI--DNNCD 759
+GQC CK +V CD C +GFY L + D FGC C C+ G+I N CD
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 760 KTTGQCHCHSRVEGRRCDQPIRAHY 784
TG C+C V G+ CDQ + H+
Sbjct: 474 SETGHCYCKRLVTGQHCDQCLPEHW 498
Score = 131 bits (317), Expect = 4e-29
Identities = 77/235 (32%), Positives = 101/235 (42%), Gaps = 30/235 (12%)
Query: 1319 TGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY 1378
T +CR +FSI++ + C CD GS C+ GGQC C+PNV+GRTC+ C G +
Sbjct: 752 TDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTF 811
Query: 1379 GF--PNCRPCHC----PSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
GF C+PC C A C+ G C C + V CDRC P + F C C
Sbjct: 812 GFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP---SCQPCQ 868
Query: 1432 CNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYAFP------DCYQCTC---- 1480
CN G+ C+ +G+C C++ G C+ C+ G+Y P C C C
Sbjct: 869 CN-----GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
Query: 1481 --NRHGTTYDVCDQNTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
R D T Q C C G CD C YF + C C C
Sbjct: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
Score = 126 bits (305), Expect = 1e-27
Identities = 82/255 (32%), Positives = 116/255 (45%), Gaps = 48/255 (18%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTP------ 420
G C CR + +C C Y D P CK C CN +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 421 --TDGLCP-CKYNYAGKSCEICEDGYYS-PE--------CKNCECNTVGSVSY-VCDKLT 467
+ G+C C++N G++CE C+ YY PE C+ C C+ GS + +CD T
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 468 --------GDCTCKSKYSGRTCNQCQAGYYNYPT-----CKPCNCDTSGTEP--SICDDV 512
G C CK G C+ C+ G+Y+ + CK C C+ GT P + CD
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 513 SGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ-CVPCNCDPTGSTSTSCSAD-GKCNCLT 570
+G C CK G CDQCL ++ L + C PC+CD G+ + SC A+ G+C+C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWG--LSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRP 533
Query: 571 NFGGAQCDQCSPGYY 585
+ G QC++ PGYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 125 bits (302), Expect = 3e-27
Identities = 79/244 (32%), Positives = 109/244 (44%), Gaps = 30/244 (12%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNC-----SGNINPQDPGSCDSI 1894
C C+ G CE C Y+ +P + + CK CNC S + + + ++
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1895 NGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD---CDSTT-- 1944
+G C C +NT G C C P +Y I N C C CD G + CDS T
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
Query: 1945 ------GTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC---GIASESTQCDDDNG 1993
G C C+ V GE CD C + L++ GC C C G CD + G
Sbjct: 418 STGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETG 477
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIG 2050
C C + VTG+ CDQC W + D GC C+C+ G ++ C A +GQC C P +IG
Sbjct: 478 HCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
Query: 2051 EKCD 2054
+C+
Sbjct: 538 RQCN 541
Score = 119 bits (287), Expect = 2e-25
Identities = 81/260 (31%), Positives = 115/260 (44%), Gaps = 38/260 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC-----------DV 1776
C C +GL+CE C + ++ LP S C C CN HS C +V
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1777 NTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ G+C +C NT+G +CE C Y H + + P C C C P S N + CD
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCD-PAGSQNEGI-CDSYT 415
Query: 1835 NGS--LIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDP 1888
+ S LI+ C C+ G C+ C G+Y + + CK C C+ G I +P
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG----CKSCACNPLGTIPGGNP 471
Query: 1889 GSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CDS G C C G C+ C P +G + C C CD G + C + +G
Sbjct: 472 --CDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQ 528
Query: 1947 CVCRPGVIGEKCDRCAPDHW 1966
C CRP +IG +C+ P ++
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 116 bits (279), Expect = 2e-24
Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 29/193 (15%)
Query: 1353 NTFGGQCP-CKPNVIGRTCSACRTGYYGFPN--------CRPCHCP-----STAICDDN- 1397
N GG C C+ N +GR C C+ YY P C C C + ICD
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 1398 --------GMCICPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
G C C NVEGE+CD CK Y + + GC C CNPLG + C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPD----CYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+G C C+ V G+ CD C+P H+ + C C C+ G + C + QC C+ ++
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
Query: 1504 RGQACDTCKEEYF 1516
G+ C+ + Y+
Sbjct: 536 IGRQCNEVEPGYY 548
Score = 116 bits (278), Expect = 2e-24
Identities = 75/224 (33%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 1868 LH-TGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
LH TG C+ C+ G+++ CD G C +C N G CN CAPG +G
Sbjct: 766 LHQTGLACE-CDPQGSLS----SVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFG--PSG 817
Query: 1927 CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C G + C+ TG C C GV +CDRC P HWG + C PC C
Sbjct: 818 CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCN--GH 872
Query: 1985 STQCDDDNGQC-RCAKGVTGKQCDQCAAGFWN----YTKDGCDHCNCNTGYSVG------ 2033
+ CD G+C C G C++C AG++ + D C C C G G
Sbjct: 873 ADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARS 932
Query: 2034 -FMCNATGQ--CECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ T Q C C PG IG +CD C + P E C C
Sbjct: 933 CYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Score = 104 bits (250), Expect = 5e-21
Identities = 70/219 (31%), Positives = 94/219 (42%), Gaps = 46/219 (21%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CD---------- 1395
G C C+ N G C C Y+ P C+ C+C +I C
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNF---DVQ--RGCDDCNCNPLGVVGNQLQCEAD 1447
G+C C N G NC++CKP+ + D++ C+ C C+P G N+ C++
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQ-NEGICDSY 414
Query: 1448 S--------GKCACRENVRGRVCDHCVPGHYAFPD-----CYQCTCNRHGTTY--DVCDQ 1492
+ G+C C+ NV G CD C G Y C C CN GT + CD
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T CYCK V GQ CD C E++ L +D DGC C C
Sbjct: 475 ETGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPCDC 512
Score = 96.7 bits (230), Expect = 1e-18
Identities = 58/183 (31%), Positives = 82/183 (44%), Gaps = 26/183 (14%)
Query: 1305 EQCASYNYYISPN----ETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCP 1360
EQC + YY P + C N G +CD T+ GQC
Sbjct: 375 EQCKPF-YYQHPERDIRDPNFCERCTCDPAGSQNEG----ICD--SYTDFSTGLIAGQCR 427
Query: 1361 CKPNVIGRTCSACRTGYYGFPN-----CRPCHC------PSTAICD-DNGMCICPKNVEG 1408
CK NV G C C+ G+Y + C+ C C P CD + G C C + V G
Sbjct: 428 CKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTG 487
Query: 1409 ENCDRCKPYTFNFDVQ-RGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
++CD+C P + GC C+C+ G + N C A+SG+C+CR ++ GR C+ P
Sbjct: 488 QHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNN--SCFAESGQCSCRPHMIGRQCNEVEP 545
Query: 1468 GHY 1470
G+Y
Sbjct: 546 GYY 548
Score = 91.9 bits (218), Expect = 4e-17
Identities = 62/202 (30%), Positives = 87/202 (43%), Gaps = 31/202 (15%)
Query: 591 LSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNY--PACEECNCDPRGVTA 647
L+C CD GS+ S CD N G C C+ N G C+ C + + C+ C C +G
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
+F C V G+ C C V R C+ C P +W C+ C CN C
Sbjct: 831 AF--CNPV-TGQ-CHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCN-----GHADDC 876
Query: 708 NTKSGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDC----DIGGSIDNNC- 758
+ +G+C+ C+ + C++CL G+Y + + D C C C D G +C
Sbjct: 877 DPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGD--HCRPCPCPDGPDSGRQFARSCY 934
Query: 759 -DKTTGQ--CHCHSRVEGRRCD 777
D T Q C C G RCD
Sbjct: 935 QDPVTLQLACVCDPGYIGSRCD 956
Score = 88.6 bits (210), Expect = 4e-16
Identities = 70/220 (31%), Positives = 97/220 (44%), Gaps = 43/220 (19%)
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIF-------SKNCTACICDE------FGMADC 1940
++G C+ C +NT G C LC FY D + S C C C+E F MA
Sbjct: 294 VHGHCM-CRHNTKGLNCELCMD-FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVY 351
Query: 1941 DSTT----GTCV-CRPGVIGEKCDRCAPDHW-----GLNTGLGCTPCNCGIASESTQ--C 1988
+T G C C+ +G C++C P ++ + C C C A + C
Sbjct: 352 LATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
Query: 1989 DDDN--------GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV--GFM 2035
D GQCRC V G+ CD C GF++ + + GC C CN ++ G
Sbjct: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP 471
Query: 2036 CNA-TGQCECLPGVIGEKCDRC-PERWVLIPQ-EGCLECD 2072
C++ TG C C V G+ CD+C PE W L +GC CD
Sbjct: 472 CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCD 511
Score = 88.2 bits (209), Expect = 5e-16
Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 31/166 (18%)
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQ-------RGCDDCNCNPLGV-----VGNQLQC 1444
+G C+C N +G NC+ C + + + C CNCN + + L
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 1445 -EADSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYD-VCDQN 1493
G C C+ N GR C+ C P +Y P+ C +CTC+ G+ + +CD
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
Query: 1494 T--------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T QC CK NV G+ CD CKE +++L ++P GC C C
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCAC 460
Score = 87.4 bits (207), Expect = 9e-16
Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTG 2029
TGL C C+ S S+ CD + GQC+C V G+ C++CA G + + GC C C+
Sbjct: 769 TGLACE-CDPQ-GSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 826
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCDRC-PERWVLIPQEGCLECDSCTD 2076
SV CN TGQC C GV +CDRC P W + C +C+ D
Sbjct: 827 GSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPC-QCNGHAD 874
Score = 80.6 bits (190), Expect = 1e-13
Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
C C+ G+L+S+ C+ GQC C+ +V R C++C G + + GC C+C + G
Sbjct: 773 CECDPQGSLSSV--CDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS---GCKPCECHLQG 827
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPTLHQFQ 792
S++ C+ TGQCHC V R+CD+ + H+ FP+ Q
Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQ 868
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 20/135 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSG---FCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C+C G C+ C EG Y L S C C CN + CD TG C C
Sbjct: 425 QCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKR 483
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRD-CLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
G HC+ C+ + G + D C C C + NN SC +E+G C+C+P
Sbjct: 484 LVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN---SC-FAESG---QCSCRP 533
Query: 1846 GYGGARCEYCAAGYY 1860
G +C GYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 40.3 bits (90), Expect = 0.13
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 8/206 (3%)
Query: 2112 ISNQTELLRPKVAQLKTVDI--GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKL 2169
+ N TE +R +V L V++ + I E + R+++ +ATD +
Sbjct: 1540 LQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASK-SATDVKVTADMVKEA 1598
Query: 2170 AEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIADKDLV 2229
E+AE+ A ++ ++A E ++ +L T +E S+ + L A Q R ++++
Sbjct: 1599 LEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIE-SETAASEETLFNASQ-RISELERNVE 1656
Query: 2230 PKKQQAEAVFLNTTTQIERMNFFV-QPVNEQAKASSHRPDLKFESLVNATRELKDKLDDM 2288
K++A A IE++ + V Q + K D K++ + N + ++ D
Sbjct: 1657 ELKRKA-AQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADA 1715
Query: 2289 LEYTDLAQHTAHT-AEELNTKNRLSK 2313
++ Q+ A T + N+K +L K
Sbjct: 1716 RRKAEMLQNEAKTLLAQANSKLQLLK 1741
>BC026018-1|AAH26018.2| 1083|Homo sapiens LAMB1 protein protein.
Length = 1083
Score = 334 bits (821), Expect = 3e-90
Identities = 167/479 (34%), Positives = 243/479 (50%), Gaps = 30/479 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C + C++C GH+ PS C PCQCNGH+D CD TG CLNC D T+G +CE
Sbjct: 136 QCHCFQGVYARQCDRCLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCE 193
Query: 1795 FCMSGYHGDATVGTPRDCLICACP-MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++GY+GD +G+ C C CP P FA SC ++C C PGY G+RC+
Sbjct: 194 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 253
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA+GY+G P + G C+PC C NI+ DP +CD G CLKC+ +T G C C
Sbjct: 254 DCASGYFGNPSE----VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 309
Query: 1914 APGFYGDAIFSKNCTACICDEFGM---------ADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
G+YGDA+ ++C C+C+ G CD TG C+C P VIG+ CDRCAP+
Sbjct: 310 RFGYYGDAL-QQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 368
Query: 1965 HWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH 2023
W L +G GC PCNC A S C++ GQC+C G G+ C +C FW C
Sbjct: 369 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRA 428
Query: 2024 CNCN-TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSV 2082
C+C+ G +TGQC C+ GV G +CD+C + + + C C C F++
Sbjct: 429 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD-CTPCHQC-----FAL 482
Query: 2083 ED-LSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTV----DIGEVTSS 2137
D + A L N T F +KA + + + + + KV+++K + E +
Sbjct: 483 WDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKN 542
Query: 2138 IKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVAD 2196
I L A+ L++ + ++S + + L +++ A VK +A+
Sbjct: 543 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAE 601
Score = 239 bits (585), Expect = 1e-61
Identities = 137/408 (33%), Positives = 195/408 (47%), Gaps = 41/408 (10%)
Query: 406 CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--PE-CKNCECNTVGSVSYV 462
C C+ G+ C P G C C+ N G++C C G + P CK CEC+ GSV+
Sbjct: 70 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 129
Query: 463 CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
C+ +TG C C R C++C G++ +P+C+PC C+ + CD V+G+C+ C+
Sbjct: 130 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADD---CDPVTGECLNCQDY 186
Query: 522 FGGPRCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTS-----TSCSADG-----KCNCLT 570
G C++CL+GYY ++G C PC C P G S SC D C C
Sbjct: 187 TMGHNCERCLAGYYGDPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDP 245
Query: 571 NFGGAQCDQCSPGYYKYP-----DCLSCNC--DVSGSIGSTCD-DNGLC-HCKSNFDGAK 621
+ G++CD C+ GY+ P C C C ++ + CD + G C C + +G
Sbjct: 246 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 305
Query: 622 CDTCREQFYN---YPACEECNCDPRGVT---ASFAGCGSVPAGELCQCKDRVQGRICNDC 675
C CR +Y C +C C+ G + + C A C C V G+ C+ C
Sbjct: 306 CQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRC 365
Query: 676 KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRL 735
P W L + GC+ CNCN A + +CN +GQC C G R C +C + F+
Sbjct: 366 APNTWQLA--SGTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFW-- 419
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
DV C CDCD G CD++TGQC C VEG RCD+ R +
Sbjct: 420 GDPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY 466
Score = 227 bits (555), Expect = 6e-58
Identities = 140/424 (33%), Positives = 191/424 (45%), Gaps = 55/424 (12%)
Query: 361 CQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEH 417
C+CDP S + C+ G+C+CRP C+ CA G F + CKPC C+L G+
Sbjct: 70 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 129
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
C P G C C + C+ C G++ P C+ C+CN G CD +TG+C C+
Sbjct: 130 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN--GHAD-DCDPVTGECLNCQDY 186
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNC----DTSGTEPSIC--DDVSGQ--CICKAG 521
G C +C AGYY P C+PC C D+ C D V+ Q C+C G
Sbjct: 187 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 246
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQC 577
+ G RCD C SGY+ C PC C T+ + D G+C CL + G C
Sbjct: 247 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 306
Query: 578 DQCSPGYY---KYPDCLSCNCDVSGSI-----GSTCD---DNGLCHCKSNFDGAKCDTCR 626
C GYY DC C C+ G++ GS C G C C N G CD C
Sbjct: 307 QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 366
Query: 627 E---QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
Q + C+ CNC+ SF + G+ CQC GR C++C+ L+W
Sbjct: 367 PNTWQLASGTGCDPCNCN---AAHSFGPSCNEFTGQ-CQCMPGFGGRTCSECQELFWGDP 422
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVF-G 742
+ C C+C+ G C+ +GQCVC + V +CD+C G+ + VF
Sbjct: 423 DVE---CRACDCDPRGI--ETPQCDQSTGQCVCVEGVEGPRCDKCTRGY-----SGVFPD 472
Query: 743 CTEC 746
CT C
Sbjct: 473 CTPC 476
Score = 202 bits (494), Expect = 1e-50
Identities = 129/414 (31%), Positives = 186/414 (44%), Gaps = 62/414 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRP-TY-YRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGR 378
GG+C C+ N G CN+C P T+ + P G C+PC+C S C +G+
Sbjct: 86 GGQC-QCRPNVVGRTCNRCAPGTFGFGPSG--------CKPCECHLQGSVNAFCNPVTGQ 136
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCE 437
C C C C G++ +P+C+PC CN + C P G C C+ G +CE
Sbjct: 137 CHCFQGVYARQCDRCLPGHWGFPSCQPCQCN---GHADDCDPVTGECLNCQDYTMGHNCE 193
Query: 438 ICEDGYY-------SPECKNCEC----NTVGSVSYVC--DKLTGD--CTCKSKYSGRTCN 482
C GYY C+ C C ++ + C D +T C C Y G C+
Sbjct: 194 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 253
Query: 483 QCQAGYYNYP-----TCKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGY 534
C +GY+ P +C+PC C + T+P CD +G+C+ C G C C GY
Sbjct: 254 DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGY 313
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCS--------ADGKCNCLTNFGGAQCDQCSPGYYK 586
Y L ++ C C C+ G+ C+ A G+C CL N G CD+C+P ++
Sbjct: 314 YGDAL--QQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ 371
Query: 587 YPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
C CNC+ + S G +C++ G C C F G C C+E F+ P C C+C
Sbjct: 372 LASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDC 431
Query: 641 DPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL-QEYNPFGCEQC 693
DPRG+ C G+ C C + V+G C+ C Y + + P C QC
Sbjct: 432 DPRGIET--PQCDQ-STGQ-CVCVEGVEGPRCDKCTRGYSGVFPDCTP--CHQC 479
Score = 180 bits (439), Expect = 7e-44
Identities = 124/364 (34%), Positives = 159/364 (43%), Gaps = 47/364 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL-PSGFCVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+CQC G +C +CA G + PSG C PC+C+ C+ TG C +C
Sbjct: 88 QCQCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQC-HCFQGVYA 145
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C+ G+ G + C C C N A CD L NCQ G
Sbjct: 146 RQCDRCLPGHWGFPS------CQPCQC------NGHADDCDPVTGECL---NCQDYTMGH 190
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSC--DSINGDCLKCVNNTA 1906
CE C AGYYG D + +GD+C+PC C + Q SC D + L CV +
Sbjct: 191 NCERCLAGYYG---DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ-LACVCDPG 246
Query: 1907 --GAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKC 1958
G+ C+ CA G++G+ + +C C C D CD TG C+ C GE C
Sbjct: 247 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 306
Query: 1959 DRCAPDHWGLNTGLGCTPCNC---GIASE-----STQCDDDNGQCRCAKGVTGKQCDQCA 2010
C ++G C C C G E QCD GQC C V G+ CD+CA
Sbjct: 307 QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 366
Query: 2011 AGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC 2068
W GCD CNCN +S G CN TGQC+C+PG G C C E + P C
Sbjct: 367 PNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVEC 426
Query: 2069 LECD 2072
CD
Sbjct: 427 RACD 430
Score = 180 bits (438), Expect = 9e-44
Identities = 131/472 (27%), Positives = 194/472 (41%), Gaps = 83/472 (17%)
Query: 188 TNVRLRLLRTKNLLGHLMSVARQDPT-VTRRYFYSIKDI--SIGGRCMCNGHADTCEPAD 244
TN + L + SV + T V R +SI + G C C+ D
Sbjct: 24 TNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCD 83
Query: 245 PAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH-------- 296
P G C+C+ N G CN+C G + + C+PC CH
Sbjct: 84 PNGGQ----CQCRPNVVGRTCNRCAPG--------TFGFGPSGCKPCECHLQGSVNAFCN 131
Query: 297 --TTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHN-------------------TEGI 335
T +C + ++ + G + G C CQ N T G
Sbjct: 132 PVTGQCHCFQGVYARQCDRCLPGHW-GFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGH 190
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-----NCEEE----SGRCECRPEFQ 386
NC +C YY D C+PC C +G +C ++ C C P +
Sbjct: 191 NCERCLAGYYG--DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYI 248
Query: 387 PPDCSSCAYGYFDYP-----NCKPCTC--NLNGTEGEHCTPTDGLC-PCKYNYAGKSCEI 438
C CA GYF P +C+PC C N++ T+ E C G C C Y+ G+ C+
Sbjct: 249 GSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 308
Query: 439 CEDGYY----SPECKNCECNTVGSV-------SYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
C GYY +C+ C CN +G+V CDK TG C C G+ C++C
Sbjct: 309 CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 368
Query: 488 YYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
+ + C PCNC+ + + C++ +GQC C GFGG C +C ++ + +
Sbjct: 369 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD---PDVE 425
Query: 545 CVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN 594
C C+CDP G + C + G+C C+ G +CD+C+ GY +PDC C+
Sbjct: 426 CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCH 477
Score = 137 bits (332), Expect = 6e-31
Identities = 83/232 (35%), Positives = 101/232 (43%), Gaps = 27/232 (11%)
Query: 1322 CREAMFSITSEYNSGARPCLC-DFMGSTELE-CNTFGGQC-PCKPNVIGRTCSACRTGYY 1378
C F SE +PC C + + +T+ E C+ G+C C + G C CR GYY
Sbjct: 255 CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYY 314
Query: 1379 GFP---NCRPC----------HCP-STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDV 1423
G +CR C HC S CD G C+C NV G+NCDRC P T+
Sbjct: 315 GDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 374
Query: 1424 QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCN 1481
GCD CNCN G C +G+C C GR C C + PD C C C+
Sbjct: 375 GTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCD 432
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCF-CF 1532
G CDQ+T QC C V G CD C Y + D CT C CF
Sbjct: 433 PRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD----CTPCHQCF 480
Score = 131 bits (317), Expect = 4e-29
Identities = 77/235 (32%), Positives = 101/235 (42%), Gaps = 30/235 (12%)
Query: 1319 TGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY 1378
T +CR +FSI++ + C CD GS C+ GGQC C+PNV+GRTC+ C G +
Sbjct: 49 TDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTF 108
Query: 1379 GF--PNCRPCHC----PSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
GF C+PC C A C+ G C C + V CDRC P + F C C
Sbjct: 109 GFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP---SCQPCQ 165
Query: 1432 CNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYAFP------DCYQCTC---- 1480
CN G+ C+ +G+C C++ G C+ C+ G+Y P C C C
Sbjct: 166 CN-----GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 220
Query: 1481 --NRHGTTYDVCDQNTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
R D T Q C C G CD C YF + C C C
Sbjct: 221 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 275
Score = 116 bits (278), Expect = 2e-24
Identities = 75/224 (33%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 1868 LH-TGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
LH TG C+ C+ G+++ CD G C +C N G CN CAPG +G
Sbjct: 63 LHQTGLACE-CDPQGSLS----SVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFG--PSG 114
Query: 1927 CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C G + C+ TG C C GV +CDRC P HWG + C PC C
Sbjct: 115 CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCN--GH 169
Query: 1985 STQCDDDNGQC-RCAKGVTGKQCDQCAAGFWN----YTKDGCDHCNCNTGYSVG------ 2033
+ CD G+C C G C++C AG++ + D C C C G G
Sbjct: 170 ADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARS 229
Query: 2034 -FMCNATGQ--CECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ T Q C C PG IG +CD C + P E C C
Sbjct: 230 CYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 273
Score = 91.9 bits (218), Expect = 4e-17
Identities = 62/202 (30%), Positives = 87/202 (43%), Gaps = 31/202 (15%)
Query: 591 LSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNY--PACEECNCDPRGVTA 647
L+C CD GS+ S CD N G C C+ N G C+ C + + C+ C C +G
Sbjct: 68 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 127
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
+F C V G+ C C V R C+ C P +W C+ C CN C
Sbjct: 128 AF--CNPV-TGQ-CHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCN-----GHADDC 173
Query: 708 NTKSGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDC----DIGGSIDNNC- 758
+ +G+C+ C+ + C++CL G+Y + + D C C C D G +C
Sbjct: 174 DPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGD--HCRPCPCPDGPDSGRQFARSCY 231
Query: 759 -DKTTGQ--CHCHSRVEGRRCD 777
D T Q C C G RCD
Sbjct: 232 QDPVTLQLACVCDPGYIGSRCD 253
Score = 87.4 bits (207), Expect = 9e-16
Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTG 2029
TGL C C+ S S+ CD + GQC+C V G+ C++CA G + + GC C C+
Sbjct: 66 TGLACE-CDPQ-GSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 123
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCDRC-PERWVLIPQEGCLECDSCTD 2076
SV CN TGQC C GV +CDRC P W + C +C+ D
Sbjct: 124 GSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPC-QCNGHAD 171
Score = 80.6 bits (190), Expect = 1e-13
Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
C C+ G+L+S+ C+ GQC C+ +V R C++C G + + GC C+C + G
Sbjct: 70 CECDPQGSLSSV--CDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS---GCKPCECHLQG 124
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPTLHQFQ 792
S++ C+ TGQCHC V R+CD+ + H+ FP+ Q
Sbjct: 125 SVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQ 165
Score = 40.3 bits (90), Expect = 0.13
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 8/206 (3%)
Query: 2112 ISNQTELLRPKVAQLKTVDI--GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKL 2169
+ N TE +R +V L V++ + I E + R+++ +ATD +
Sbjct: 837 LQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASK-SATDVKVTADMVKEA 895
Query: 2170 AEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIADKDLV 2229
E+AE+ A ++ ++A E ++ +L T +E S+ + L A Q R ++++
Sbjct: 896 LEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIE-SETAASEETLFNASQ-RISELERNVE 953
Query: 2230 PKKQQAEAVFLNTTTQIERMNFFV-QPVNEQAKASSHRPDLKFESLVNATRELKDKLDDM 2288
K++A A IE++ + V Q + K D K++ + N + ++ D
Sbjct: 954 ELKRKA-AQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADA 1012
Query: 2289 LEYTDLAQHTAHT-AEELNTKNRLSK 2313
++ Q+ A T + N+K +L K
Sbjct: 1013 RRKAEMLQNEAKTLLAQANSKLQLLK 1038
>M61951-1|AAA59486.1| 1786|Homo sapiens laminin B1 protein.
Length = 1786
Score = 334 bits (820), Expect = 5e-90
Identities = 167/479 (34%), Positives = 243/479 (50%), Gaps = 30/479 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C + C++C GH+ PS C PCQCNGH+D CD TG CLNC D T+G +CE
Sbjct: 839 QCHCFQGVYARQCDRCLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 1795 FCMSGYHGDATVGTPRDCLICACP-MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++GY+GD +G+ C C CP P FA SC ++C C PGY G+RC+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA+GY+G P + G C+PC C NI+ DP +CD G CLKC+ +T G C C
Sbjct: 957 DCASGYFGNPSE----VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
Query: 1914 APGFYGDAIFSKNCTACICDEFGM---------ADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
G+YGDA+ ++C C+C+ G CD TG C+C P VIG+ CDRCAP+
Sbjct: 1013 RFGYYGDAL-RQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 1965 HWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH 2023
W L +G GC PCNC A S C++ GQC+C G G+ C +C FW C
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRA 1131
Query: 2024 CNCN-TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSV 2082
C+C+ G +TGQC C+ GV G +CD+C + + + C C C F++
Sbjct: 1132 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD-CTPCHQC-----FAL 1185
Query: 2083 ED-LSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTV----DIGEVTSS 2137
D + A L N T F +KA + + + + + KV+++K + E +
Sbjct: 1186 WDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKN 1245
Query: 2138 IKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVAD 2196
I L A+ L++ + ++S + + L +++ A VK +A+
Sbjct: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAE 1304
Score = 241 bits (591), Expect = 3e-62
Identities = 137/466 (29%), Positives = 230/466 (49%), Gaps = 46/466 (9%)
Query: 50 YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDY 109
+A + + WWQS G++ V + +DL EFH ++ + + RP ++E+S+D+
Sbjct: 103 FAPNRLKIWWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTF-KTFRPAAMLIERSSDF 156
Query: 110 GKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR 169
GKT+ ++YF+ DCE F S P+ K D +IC + YS I P +GE+ L+
Sbjct: 157 GKTWGVYRYFA---YDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPA 213
Query: 170 PSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGG 229
++ + Q + TN+R++ ++ L +L+ +R + + +Y+Y++ D+ + G
Sbjct: 214 FKIEDPYSPRI-QNLLKITNLRIKFVKLHTLGDNLLD-SRME--IREKYYYAVYDMVVRG 269
Query: 230 RCMCNGHADTCEPADPAGN-LNILV---CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
C C GHA C P D + +V C C+HNT G C C + WR ++ +
Sbjct: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
+C+ CNC+ H+ C +D +++ + GG C +CQHNT G NC +C+P YY
Sbjct: 330 NACKKCNCNEHSISCHFD-------MAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYY 382
Query: 346 RPYGKRWDELDVCQPCQCDPHFS--TGNCEEE--------SGRCECRPEFQPPDCSSCAY 395
+ + + + C+ C CDP S G C+ +G+C C+ + C C
Sbjct: 383 QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKE 442
Query: 396 GYFDYPN-----CKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--- 445
G++D + CK C CN GT G C G C CK G+ C+ C ++
Sbjct: 443 GFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSN 502
Query: 446 --PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
C+ C+C+ G+++ C +G C+C+ GR CN+ + GYY
Sbjct: 503 DLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 239 bits (584), Expect = 2e-61
Identities = 137/408 (33%), Positives = 195/408 (47%), Gaps = 41/408 (10%)
Query: 406 CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--PE-CKNCECNTVGSVSYV 462
C C+ G+ C P G C C+ N G++C C G + P CK CEC+ GSV+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 463 CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
C+ +TG C C R C++C G++ +P+C+PC C+ + CD V+G+C+ C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADD---CDPVTGECLNCQDY 889
Query: 522 FGGPRCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTS-----TSCSADG-----KCNCLT 570
G C++CL+GYY ++G C PC C P G S SC D C C
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDP 948
Query: 571 NFGGAQCDQCSPGYYKYP-----DCLSCNC--DVSGSIGSTCD-DNGLC-HCKSNFDGAK 621
+ G++CD C+ GY+ P C C C ++ + CD + G C C + +G
Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 622 CDTCREQFYN---YPACEECNCDPRGVT---ASFAGCGSVPAGELCQCKDRVQGRICNDC 675
C CR +Y C +C C+ G + + C A C C V G+ C+ C
Sbjct: 1009 CQFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRC 1068
Query: 676 KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRL 735
P W L + GC+ CNCN A + +CN +GQC C G R C +C + F+
Sbjct: 1069 APNTWQLA--SGTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFW-- 1122
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
DV C CDCD G CD++TGQC C VEG RCD+ R +
Sbjct: 1123 GDPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY 1169
Score = 227 bits (554), Expect = 8e-58
Identities = 140/424 (33%), Positives = 191/424 (45%), Gaps = 55/424 (12%)
Query: 361 CQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEH 417
C+CDP S + C+ G+C+CRP C+ CA G F + CKPC C+L G+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
C P G C C + C+ C G++ P C+ C+CN G CD +TG+C C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN--GHAD-DCDPVTGECLNCQDY 889
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNC----DTSGTEPSIC--DDVSGQ--CICKAG 521
G C +C AGYY P C+PC C D+ C D V+ Q C+C G
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 949
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQC 577
+ G RCD C SGY+ C PC C T+ + D G+C CL + G C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 578 DQCSPGYY---KYPDCLSCNCDVSGSI-----GSTCD---DNGLCHCKSNFDGAKCDTCR 626
C GYY DC C C+ G++ GS C G C C N G CD C
Sbjct: 1010 QFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 627 E---QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
Q + C+ CNC+ SF + G+ CQC GR C++C+ L+W
Sbjct: 1070 PNTWQLASGTGCDPCNCN---AAHSFGPSCNEFTGQ-CQCMPGFGGRTCSECQELFWGDP 1125
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVF-G 742
+ C C+C+ G C+ +GQCVC + V +CD+C G+ + VF
Sbjct: 1126 DVE---CRACDCDPRGI--ETPQCDQSTGQCVCVEGVEGPRCDKCTRGY-----SGVFPD 1175
Query: 743 CTEC 746
CT C
Sbjct: 1176 CTPC 1179
Score = 202 bits (492), Expect = 3e-50
Identities = 129/414 (31%), Positives = 185/414 (44%), Gaps = 62/414 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRP-TY-YRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGR 378
GG+C C+ N G CN+C P T+ + P G C+PC+C S C +G+
Sbjct: 789 GGQC-QCRPNVVGRTCNRCAPGTFGFGPSG--------CKPCECHLQGSVNAFCNPVTGQ 839
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCE 437
C C C C G++ +P+C+PC CN + C P G C C+ G +CE
Sbjct: 840 CHCFQGVYARQCDRCLPGHWGFPSCQPCQCN---GHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 438 ICEDGYY-------SPECKNCEC----NTVGSVSYVC--DKLTGD--CTCKSKYSGRTCN 482
C GYY C+ C C ++ + C D +T C C Y G C+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 483 QCQAGYYNYP-----TCKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGY 534
C +GY+ P +C+PC C + T+P CD +G+C+ C G C C GY
Sbjct: 957 DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCS--------ADGKCNCLTNFGGAQCDQCSPGYYK 586
Y L + C C C+ G+ C+ A G+C CL N G CD+C+P ++
Sbjct: 1017 YGDAL--RQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ 1074
Query: 587 YPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
C CNC+ + S G +C++ G C C F G C C+E F+ P C C+C
Sbjct: 1075 LASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDC 1134
Query: 641 DPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL-QEYNPFGCEQC 693
DPRG+ C G+ C C + V+G C+ C Y + + P C QC
Sbjct: 1135 DPRGIET--PQCDQ-STGQ-CVCVEGVEGPRCDKCTRGYSGVFPDCTP--CHQC 1182
Score = 180 bits (439), Expect = 7e-44
Identities = 124/364 (34%), Positives = 159/364 (43%), Gaps = 47/364 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL-PSGFCVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+CQC G +C +CA G + PSG C PC+C+ C+ TG C +C
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQC-HCFQGVYA 848
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C+ G+ G + C C C N A CD L NCQ G
Sbjct: 849 RQCDRCLPGHWGFPS------CQPCQC------NGHADDCDPVTGECL---NCQDYTMGH 893
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSC--DSINGDCLKCVNNTA 1906
CE C AGYYG D + +GD+C+PC C + Q SC D + L CV +
Sbjct: 894 NCERCLAGYYG---DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ-LACVCDPG 949
Query: 1907 --GAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKC 1958
G+ C+ CA G++G+ + +C C C D CD TG C+ C GE C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 1959 DRCAPDHWGLNTGLGCTPCNC---GIASE-----STQCDDDNGQCRCAKGVTGKQCDQCA 2010
C ++G C C C G E QCD GQC C V G+ CD+CA
Sbjct: 1010 QFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 2011 AGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC 2068
W GCD CNCN +S G CN TGQC+C+PG G C C E + P C
Sbjct: 1070 PNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVEC 1129
Query: 2069 LECD 2072
CD
Sbjct: 1130 RACD 1133
Score = 180 bits (438), Expect = 9e-44
Identities = 131/472 (27%), Positives = 194/472 (41%), Gaps = 83/472 (17%)
Query: 188 TNVRLRLLRTKNLLGHLMSVARQDPT-VTRRYFYSIKDI--SIGGRCMCNGHADTCEPAD 244
TN + L + SV + T V R +SI + G C C+ D
Sbjct: 727 TNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCD 786
Query: 245 PAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH-------- 296
P G C+C+ N G CN+C G + + C+PC CH
Sbjct: 787 PNGGQ----CQCRPNVVGRTCNRCAPG--------TFGFGPSGCKPCECHLQGSVNAFCN 834
Query: 297 --TTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHN-------------------TEGI 335
T +C + ++ + G + G C CQ N T G
Sbjct: 835 PVTGQCHCFQGVYARQCDRCLPGHW-GFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-----NCEEE----SGRCECRPEFQ 386
NC +C YY D C+PC C +G +C ++ C C P +
Sbjct: 894 NCERCLAGYYG--DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYI 951
Query: 387 PPDCSSCAYGYFDYP-----NCKPCTC--NLNGTEGEHCTPTDGLC-PCKYNYAGKSCEI 438
C CA GYF P +C+PC C N++ T+ E C G C C Y+ G+ C+
Sbjct: 952 GSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 1011
Query: 439 CEDGYYS----PECKNCECNTVGSV-------SYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
C GYY +C+ C CN +G+V CDK TG C C G+ C++C
Sbjct: 1012 CRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 488 YYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
+ + C PCNC+ + + C++ +GQC C GFGG C +C ++ + +
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD---PDVE 1128
Query: 545 CVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN 594
C C+CDP G + C + G+C C+ G +CD+C+ GY +PDC C+
Sbjct: 1129 CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCH 1180
Score = 172 bits (419), Expect = 2e-41
Identities = 99/328 (30%), Positives = 155/328 (47%), Gaps = 36/328 (10%)
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC---------DVSGSIGST 604
G C C N G C+ C Y+ P C CNC D++ + +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 605 CDDNGLCH-CKSNFDGAKCDTCREQFYNYPA--------CEECNCDP-----RGVTASFA 650
G+C C+ N G C+ C+ +Y +P CE C CDP G+ S+
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
+ C+CK V+G C+ CK +++L +PFGC+ C CN GT+ C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 711 SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSR 770
+G C CK+ V + CDQCL + L +ND+ GC CDCD+GG+++N+C +GQC C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
Query: 771 VEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSGP--VRYRNSEEVFPEYSWKGYVVFSLL 828
+ GR+C++ +YF TL + YE E+ G V + ++ P ++ G+V
Sbjct: 535 MIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEG 594
Query: 829 QNEVINIIQITKSSLYRMVLKYANPLRD 856
I I S Y ++++Y L D
Sbjct: 595 AYLEFFIDNIPYSMEYDILIRYEPQLPD 622
Score = 147 bits (355), Expect = 1e-33
Identities = 95/287 (33%), Positives = 131/287 (45%), Gaps = 36/287 (12%)
Query: 1765 CQCNGHSDQCDVNTGI-----------CLNCADNTIGDHCEFCMSGYHG----DATVGTP 1809
C C GH+ +C G C+ C NT G +CE CM YH A
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 1810 RDCLICACPMPYPSNNFALSCDLSE-NGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTD 1867
C C C S +F ++ L+ N S C+ CQ G CE C YY PE D
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE-RD 388
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDS--------INGDCLKCVNNTAGAACNLCAPGFYG 1919
+ ++C+ C C Q+ G CDS I G C +C N G C++C GFY
Sbjct: 389 IRDPNFCERCTCDP-AGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYD 446
Query: 1920 DAIFSK-NCTACICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL-G 1973
+ C +C C+ G CDS TG C C+ V G+ CD+C P+HWGL+ L G
Sbjct: 447 LSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDG 506
Query: 1974 CTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD 2019
C PC+C + + C ++GQC C + G+QC++ G++ T D
Sbjct: 507 CRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLD 553
Score = 138 bits (334), Expect = 3e-31
Identities = 91/294 (30%), Positives = 136/294 (46%), Gaps = 57/294 (19%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY----R 346
C C+ H +EC +E ++ G G C+ C+HNT+G+NC C Y+ R
Sbjct: 271 CFCYGHASECAPVDGFNE-----EVEGMVHG--HCM-CRHNTKGLNCELCMDFYHDLPWR 322
Query: 347 PYGKRWDELDVCQPCQCDPH-----------FSTGNCEEESGRCE-CRPEFQPPDCSSCA 394
P R + C+ C C+ H +TGN G C+ C+ +C C
Sbjct: 323 PAEGR--NSNACKKCNCNEHSISCHFDMAVYLATGNVS--GGVCDDCQHNTMGRNCEQCK 378
Query: 395 YGYFDYPN--------CKPCTCNLNGTEGEH-CTP-TD-------GLCPCKYNYAGKSCE 437
Y+ +P C+ CTC+ G++ E C TD G C CK N G+ C+
Sbjct: 379 PFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCD 438
Query: 438 ICEDGYY--SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
+C++G+Y S E CK+C CN +G++ CD TG C CK +G+ C+QC ++
Sbjct: 439 VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHW 498
Query: 490 NYPT----CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
C+PC+CD G + C SGQC C+ G +C++ GYY L
Sbjct: 499 GLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATL 552
Score = 138 bits (333), Expect = 5e-31
Identities = 86/260 (33%), Positives = 119/260 (45%), Gaps = 43/260 (16%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYY----MQVLGRERQ-CVPCNC---------DPTGSTS 557
V G C+C+ G C+ C+ Y+ GR C CNC D +
Sbjct: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
Query: 558 TSCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIG-STCDD 607
T + G C+ C N G C+QC P YY++P+ C C CD +GS CD
Sbjct: 354 TGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
Query: 608 ---------NGLCHCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFAGCG 653
G C CK N +G CD C+E FY+ + C+ C C+P G C
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
S G C CK V G+ C+ C P +W L + GC C+C+L G LN+ +C +SGQ
Sbjct: 474 S-ETGH-CYCKRLVTGQHCDQCLPEHWGLSN-DLDGCRPCDCDLGGALNN--SCFAESGQ 528
Query: 714 CVCKQHVGERQCDQCLDGFY 733
C C+ H+ RQC++ G+Y
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 137 bits (332), Expect = 6e-31
Identities = 83/232 (35%), Positives = 101/232 (43%), Gaps = 27/232 (11%)
Query: 1322 CREAMFSITSEYNSGARPCLC-DFMGSTELE-CNTFGGQC-PCKPNVIGRTCSACRTGYY 1378
C F SE +PC C + + +T+ E C+ G+C C + G C CR GYY
Sbjct: 958 CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
Query: 1379 GFP---NCRPC----------HCP-STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDV 1423
G +CR C HC S CD G C+C NV G+NCDRC P T+
Sbjct: 1018 GDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 1077
Query: 1424 QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCN 1481
GCD CNCN G C +G+C C GR C C + PD C C C+
Sbjct: 1078 GTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCD 1135
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCF-CF 1532
G CDQ+T QC C V G CD C Y + D CT C CF
Sbjct: 1136 PRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD----CTPCHQCF 1183
Score = 132 bits (319), Expect = 2e-29
Identities = 70/205 (34%), Positives = 101/205 (49%), Gaps = 29/205 (14%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASF-----AGC 652
+G C C+ N G C+ C + +++ P AC++CNC+ ++ F
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQE---YNPFGCEQCNCNLAGTLNSLGACNT 709
G+V G C+ GR C CKP Y+ E +P CE+C C+ AG+ N G C++
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE-GICDS 413
Query: 710 K--------SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSI--DNNCD 759
+GQC CK +V CD C +GFY L + D FGC C C+ G+I N CD
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 760 KTTGQCHCHSRVEGRRCDQPIRAHY 784
TG C+C V G+ CDQ + H+
Sbjct: 474 SETGHCYCKRLVTGQHCDQCLPEHW 498
Score = 131 bits (317), Expect = 4e-29
Identities = 77/235 (32%), Positives = 101/235 (42%), Gaps = 30/235 (12%)
Query: 1319 TGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY 1378
T +CR +FSI++ + C CD GS C+ GGQC C+PNV+GRTC+ C G +
Sbjct: 752 TDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTF 811
Query: 1379 GF--PNCRPCHC----PSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
GF C+PC C A C+ G C C + V CDRC P + F C C
Sbjct: 812 GFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP---SCQPCQ 868
Query: 1432 CNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYAFP------DCYQCTC---- 1480
CN G+ C+ +G+C C++ G C+ C+ G+Y P C C C
Sbjct: 869 CN-----GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
Query: 1481 --NRHGTTYDVCDQNTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
R D T Q C C G CD C YF + C C C
Sbjct: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
Score = 126 bits (305), Expect = 1e-27
Identities = 82/255 (32%), Positives = 116/255 (45%), Gaps = 48/255 (18%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTP------ 420
G C CR + +C C Y D P CK C CN +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 421 --TDGLCP-CKYNYAGKSCEICEDGYYS-PE--------CKNCECNTVGSVSY-VCDKLT 467
+ G+C C++N G++CE C+ YY PE C+ C C+ GS + +CD T
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 468 --------GDCTCKSKYSGRTCNQCQAGYYNYPT-----CKPCNCDTSGTEP--SICDDV 512
G C CK G C+ C+ G+Y+ + CK C C+ GT P + CD
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 513 SGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ-CVPCNCDPTGSTSTSCSAD-GKCNCLT 570
+G C CK G CDQCL ++ L + C PC+CD G+ + SC A+ G+C+C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWG--LSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRP 533
Query: 571 NFGGAQCDQCSPGYY 585
+ G QC++ PGYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 125 bits (302), Expect = 3e-27
Identities = 79/244 (32%), Positives = 109/244 (44%), Gaps = 30/244 (12%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNC-----SGNINPQDPGSCDSI 1894
C C+ G CE C Y+ +P + + CK CNC S + + + ++
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1895 NGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD---CDSTT-- 1944
+G C C +NT G C C P +Y I N C C CD G + CDS T
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
Query: 1945 ------GTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC---GIASESTQCDDDNG 1993
G C C+ V GE CD C + L++ GC C C G CD + G
Sbjct: 418 STGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETG 477
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIG 2050
C C + VTG+ CDQC W + D GC C+C+ G ++ C A +GQC C P +IG
Sbjct: 478 HCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
Query: 2051 EKCD 2054
+C+
Sbjct: 538 RQCN 541
Score = 119 bits (287), Expect = 2e-25
Identities = 81/260 (31%), Positives = 115/260 (44%), Gaps = 38/260 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC-----------DV 1776
C C +GL+CE C + ++ LP S C C CN HS C +V
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1777 NTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ G+C +C NT+G +CE C Y H + + P C C C P S N + CD
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCD-PAGSQNEGI-CDSYT 415
Query: 1835 NGS--LIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDP 1888
+ S LI+ C C+ G C+ C G+Y + + CK C C+ G I +P
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG----CKSCACNPLGTIPGGNP 471
Query: 1889 GSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CDS G C C G C+ C P +G + C C CD G + C + +G
Sbjct: 472 --CDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQ 528
Query: 1947 CVCRPGVIGEKCDRCAPDHW 1966
C CRP +IG +C+ P ++
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 116 bits (279), Expect = 2e-24
Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 29/193 (15%)
Query: 1353 NTFGGQCP-CKPNVIGRTCSACRTGYYGFPN--------CRPCHCP-----STAICDDN- 1397
N GG C C+ N +GR C C+ YY P C C C + ICD
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 1398 --------GMCICPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
G C C NVEGE+CD CK Y + + GC C CNPLG + C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPD----CYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+G C C+ V G+ CD C+P H+ + C C C+ G + C + QC C+ ++
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
Query: 1504 RGQACDTCKEEYF 1516
G+ C+ + Y+
Sbjct: 536 IGRQCNEVEPGYY 548
Score = 116 bits (278), Expect = 2e-24
Identities = 75/224 (33%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 1868 LH-TGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
LH TG C+ C+ G+++ CD G C +C N G CN CAPG +G
Sbjct: 766 LHQTGLACE-CDPQGSLS----SVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFG--PSG 817
Query: 1927 CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C G + C+ TG C C GV +CDRC P HWG + C PC C
Sbjct: 818 CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCN--GH 872
Query: 1985 STQCDDDNGQC-RCAKGVTGKQCDQCAAGFWN----YTKDGCDHCNCNTGYSVG------ 2033
+ CD G+C C G C++C AG++ + D C C C G G
Sbjct: 873 ADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARS 932
Query: 2034 -FMCNATGQ--CECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ T Q C C PG IG +CD C + P E C C
Sbjct: 933 CYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Score = 104 bits (250), Expect = 5e-21
Identities = 70/219 (31%), Positives = 94/219 (42%), Gaps = 46/219 (21%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CD---------- 1395
G C C+ N G C C Y+ P C+ C+C +I C
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNF---DVQ--RGCDDCNCNPLGVVGNQLQCEAD 1447
G+C C N G NC++CKP+ + D++ C+ C C+P G N+ C++
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQ-NEGICDSY 414
Query: 1448 S--------GKCACRENVRGRVCDHCVPGHYAFPD-----CYQCTCNRHGTTY--DVCDQ 1492
+ G+C C+ NV G CD C G Y C C CN GT + CD
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T CYCK V GQ CD C E++ L +D DGC C C
Sbjct: 475 ETGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPCDC 512
Score = 96.7 bits (230), Expect = 1e-18
Identities = 58/183 (31%), Positives = 82/183 (44%), Gaps = 26/183 (14%)
Query: 1305 EQCASYNYYISPN----ETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCP 1360
EQC + YY P + C N G +CD T+ GQC
Sbjct: 375 EQCKPF-YYQHPERDIRDPNFCERCTCDPAGSQNEG----ICD--SYTDFSTGLIAGQCR 427
Query: 1361 CKPNVIGRTCSACRTGYYGFPN-----CRPCHC------PSTAICD-DNGMCICPKNVEG 1408
CK NV G C C+ G+Y + C+ C C P CD + G C C + V G
Sbjct: 428 CKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTG 487
Query: 1409 ENCDRCKPYTFNFDVQ-RGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
++CD+C P + GC C+C+ G + N C A+SG+C+CR ++ GR C+ P
Sbjct: 488 QHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNN--SCFAESGQCSCRPHMIGRQCNEVEP 545
Query: 1468 GHY 1470
G+Y
Sbjct: 546 GYY 548
Score = 91.9 bits (218), Expect = 4e-17
Identities = 62/202 (30%), Positives = 87/202 (43%), Gaps = 31/202 (15%)
Query: 591 LSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNY--PACEECNCDPRGVTA 647
L+C CD GS+ S CD N G C C+ N G C+ C + + C+ C C +G
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
+F C V G+ C C V R C+ C P +W C+ C CN C
Sbjct: 831 AF--CNPV-TGQ-CHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCN-----GHADDC 876
Query: 708 NTKSGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDC----DIGGSIDNNC- 758
+ +G+C+ C+ + C++CL G+Y + + D C C C D G +C
Sbjct: 877 DPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGD--HCRPCPCPDGPDSGRQFARSCY 934
Query: 759 -DKTTGQ--CHCHSRVEGRRCD 777
D T Q C C G RCD
Sbjct: 935 QDPVTLQLACVCDPGYIGSRCD 956
Score = 88.6 bits (210), Expect = 4e-16
Identities = 70/220 (31%), Positives = 97/220 (44%), Gaps = 43/220 (19%)
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIF-------SKNCTACICDE------FGMADC 1940
++G C+ C +NT G C LC FY D + S C C C+E F MA
Sbjct: 294 VHGHCM-CRHNTKGLNCELCMD-FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVY 351
Query: 1941 DSTT----GTCV-CRPGVIGEKCDRCAPDHW-----GLNTGLGCTPCNCGIASESTQ--C 1988
+T G C C+ +G C++C P ++ + C C C A + C
Sbjct: 352 LATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
Query: 1989 DDDN--------GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV--GFM 2035
D GQCRC V G+ CD C GF++ + + GC C CN ++ G
Sbjct: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP 471
Query: 2036 CNA-TGQCECLPGVIGEKCDRC-PERWVLIPQ-EGCLECD 2072
C++ TG C C V G+ CD+C PE W L +GC CD
Sbjct: 472 CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCD 511
Score = 88.2 bits (209), Expect = 5e-16
Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 31/166 (18%)
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQ-------RGCDDCNCNPLGV-----VGNQLQC 1444
+G C+C N +G NC+ C + + + C CNCN + + L
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 1445 -EADSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYD-VCDQN 1493
G C C+ N GR C+ C P +Y P+ C +CTC+ G+ + +CD
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
Query: 1494 T--------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T QC CK NV G+ CD CKE +++L ++P GC C C
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCAC 460
Score = 87.4 bits (207), Expect = 9e-16
Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTG 2029
TGL C C+ S S+ CD + GQC+C V G+ C++CA G + + GC C C+
Sbjct: 769 TGLACE-CDPQ-GSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 826
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCDRC-PERWVLIPQEGCLECDSCTD 2076
SV CN TGQC C GV +CDRC P W + C +C+ D
Sbjct: 827 GSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPC-QCNGHAD 874
Score = 80.6 bits (190), Expect = 1e-13
Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
C C+ G+L+S+ C+ GQC C+ +V R C++C G + + GC C+C + G
Sbjct: 773 CECDPQGSLSSV--CDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS---GCKPCECHLQG 827
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPTLHQFQ 792
S++ C+ TGQCHC V R+CD+ + H+ FP+ Q
Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQ 868
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 20/135 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSG---FCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C+C G C+ C EG Y L S C C CN + CD TG C C
Sbjct: 425 QCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKR 483
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRD-CLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
G HC+ C+ + G + D C C C + NN SC +E+G C+C+P
Sbjct: 484 LVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN---SC-FAESG---QCSCRP 533
Query: 1846 GYGGARCEYCAAGYY 1860
G +C GYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 40.3 bits (90), Expect = 0.13
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 8/206 (3%)
Query: 2112 ISNQTELLRPKVAQLKTVDI--GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKL 2169
+ N TE +R +V L V++ + I E + R+++ +ATD +
Sbjct: 1540 LQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASK-SATDVKVTADMVKEA 1598
Query: 2170 AEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIADKDLV 2229
E+AE+ A ++ ++A E ++ +L T +E S+ + L A Q R ++++
Sbjct: 1599 LEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIE-SETAASEETLFNASQ-RISELERNVE 1656
Query: 2230 PKKQQAEAVFLNTTTQIERMNFFV-QPVNEQAKASSHRPDLKFESLVNATRELKDKLDDM 2288
K++A A IE++ + V Q + K D K++ + N + ++ D
Sbjct: 1657 ELKRKA-AQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADA 1715
Query: 2289 LEYTDLAQHTAHT-AEELNTKNRLSK 2313
++ Q+ A T + N+K +L K
Sbjct: 1716 RRKAEMLQNEAKTLLAQANSKLQLLK 1741
>M61916-1|AAA59482.1| 1786|Homo sapiens laminin B1 protein.
Length = 1786
Score = 334 bits (820), Expect = 5e-90
Identities = 167/479 (34%), Positives = 243/479 (50%), Gaps = 30/479 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C + C++C GH+ PS C PCQCNGH+D CD TG CLNC D T+G +CE
Sbjct: 839 QCHCFQGVYARQCDRCLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 1795 FCMSGYHGDATVGTPRDCLICACP-MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++GY+GD +G+ C C CP P FA SC ++C C PGY G+RC+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA+GY+G P + G C+PC C NI+ DP +CD G CLKC+ +T G C C
Sbjct: 957 DCASGYFGNPSE----VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
Query: 1914 APGFYGDAIFSKNCTACICDEFGM---------ADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
G+YGDA+ ++C C+C+ G CD TG C+C P VIG+ CDRCAP+
Sbjct: 1013 RFGYYGDAL-RQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 1965 HWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH 2023
W L +G GC PCNC A S C++ GQC+C G G+ C +C FW C
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRA 1131
Query: 2024 CNCN-TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSV 2082
C+C+ G +TGQC C+ GV G +CD+C + + + C C C F++
Sbjct: 1132 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD-CTPCHQC-----FAL 1185
Query: 2083 ED-LSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTV----DIGEVTSS 2137
D + A L N T F +KA + + + + + KV+++K + E +
Sbjct: 1186 WDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKN 1245
Query: 2138 IKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVAD 2196
I L A+ L++ + ++S + + L +++ A VK +A+
Sbjct: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAE 1304
Score = 241 bits (591), Expect = 3e-62
Identities = 137/466 (29%), Positives = 230/466 (49%), Gaps = 46/466 (9%)
Query: 50 YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDY 109
+A + + WWQS G++ V + +DL EFH ++ + + RP ++E+S+D+
Sbjct: 103 FAPNRLKIWWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTF-KTFRPAAMLIERSSDF 156
Query: 110 GKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR 169
GKT+ ++YF+ DCE F S P+ K D +IC + YS I P +GE+ L+
Sbjct: 157 GKTWGVYRYFA---YDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPA 213
Query: 170 PSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGG 229
++ + Q + TN+R++ ++ L +L+ +R + + +Y+Y++ D+ + G
Sbjct: 214 FKIEDPYSPRI-QNLLKITNLRIKFVKLHTLGDNLLD-SRME--IREKYYYAVYDMVVRG 269
Query: 230 RCMCNGHADTCEPADPAGN-LNILV---CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
C C GHA C P D + +V C C+HNT G C C + WR ++ +
Sbjct: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
+C+ CNC+ H+ C +D +++ + GG C +CQHNT G NC +C+P YY
Sbjct: 330 NACKKCNCNEHSISCHFD-------MAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYY 382
Query: 346 RPYGKRWDELDVCQPCQCDPHFS--TGNCEEE--------SGRCECRPEFQPPDCSSCAY 395
+ + + + C+ C CDP S G C+ +G+C C+ + C C
Sbjct: 383 QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKE 442
Query: 396 GYFDYPN-----CKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--- 445
G++D + CK C CN GT G C G C CK G+ C+ C ++
Sbjct: 443 GFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSN 502
Query: 446 --PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
C+ C+C+ G+++ C +G C+C+ GR CN+ + GYY
Sbjct: 503 DLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 239 bits (584), Expect = 2e-61
Identities = 137/408 (33%), Positives = 195/408 (47%), Gaps = 41/408 (10%)
Query: 406 CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--PE-CKNCECNTVGSVSYV 462
C C+ G+ C P G C C+ N G++C C G + P CK CEC+ GSV+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 463 CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
C+ +TG C C R C++C G++ +P+C+PC C+ + CD V+G+C+ C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADD---CDPVTGECLNCQDY 889
Query: 522 FGGPRCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTS-----TSCSADG-----KCNCLT 570
G C++CL+GYY ++G C PC C P G S SC D C C
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDP 948
Query: 571 NFGGAQCDQCSPGYYKYP-----DCLSCNC--DVSGSIGSTCD-DNGLC-HCKSNFDGAK 621
+ G++CD C+ GY+ P C C C ++ + CD + G C C + +G
Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 622 CDTCREQFYN---YPACEECNCDPRGVT---ASFAGCGSVPAGELCQCKDRVQGRICNDC 675
C CR +Y C +C C+ G + + C A C C V G+ C+ C
Sbjct: 1009 CQFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRC 1068
Query: 676 KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRL 735
P W L + GC+ CNCN A + +CN +GQC C G R C +C + F+
Sbjct: 1069 APNTWQLA--SGTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFW-- 1122
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
DV C CDCD G CD++TGQC C VEG RCD+ R +
Sbjct: 1123 GDPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY 1169
Score = 227 bits (554), Expect = 8e-58
Identities = 140/424 (33%), Positives = 191/424 (45%), Gaps = 55/424 (12%)
Query: 361 CQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEH 417
C+CDP S + C+ G+C+CRP C+ CA G F + CKPC C+L G+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
C P G C C + C+ C G++ P C+ C+CN G CD +TG+C C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN--GHAD-DCDPVTGECLNCQDY 889
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNC----DTSGTEPSIC--DDVSGQ--CICKAG 521
G C +C AGYY P C+PC C D+ C D V+ Q C+C G
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 949
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQC 577
+ G RCD C SGY+ C PC C T+ + D G+C CL + G C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 578 DQCSPGYY---KYPDCLSCNCDVSGSI-----GSTCD---DNGLCHCKSNFDGAKCDTCR 626
C GYY DC C C+ G++ GS C G C C N G CD C
Sbjct: 1010 QFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 627 E---QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
Q + C+ CNC+ SF + G+ CQC GR C++C+ L+W
Sbjct: 1070 PNTWQLASGTGCDPCNCN---AAHSFGPSCNEFTGQ-CQCMPGFGGRTCSECQELFWGDP 1125
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVF-G 742
+ C C+C+ G C+ +GQCVC + V +CD+C G+ + VF
Sbjct: 1126 DVE---CRACDCDPRGI--ETPQCDQSTGQCVCVEGVEGPRCDKCTRGY-----SGVFPD 1175
Query: 743 CTEC 746
CT C
Sbjct: 1176 CTPC 1179
Score = 202 bits (492), Expect = 3e-50
Identities = 129/414 (31%), Positives = 185/414 (44%), Gaps = 62/414 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRP-TY-YRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGR 378
GG+C C+ N G CN+C P T+ + P G C+PC+C S C +G+
Sbjct: 789 GGQC-QCRPNVVGRTCNRCAPGTFGFGPSG--------CKPCECHLQGSVNAFCNPVTGQ 839
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCE 437
C C C C G++ +P+C+PC CN + C P G C C+ G +CE
Sbjct: 840 CHCFQGVYARQCDRCLPGHWGFPSCQPCQCN---GHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 438 ICEDGYY-------SPECKNCEC----NTVGSVSYVC--DKLTGD--CTCKSKYSGRTCN 482
C GYY C+ C C ++ + C D +T C C Y G C+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 483 QCQAGYYNYP-----TCKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGY 534
C +GY+ P +C+PC C + T+P CD +G+C+ C G C C GY
Sbjct: 957 DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCS--------ADGKCNCLTNFGGAQCDQCSPGYYK 586
Y L + C C C+ G+ C+ A G+C CL N G CD+C+P ++
Sbjct: 1017 YGDAL--RQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ 1074
Query: 587 YPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
C CNC+ + S G +C++ G C C F G C C+E F+ P C C+C
Sbjct: 1075 LASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDC 1134
Query: 641 DPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL-QEYNPFGCEQC 693
DPRG+ C G+ C C + V+G C+ C Y + + P C QC
Sbjct: 1135 DPRGIET--PQCDQ-STGQ-CVCVEGVEGPRCDKCTRGYSGVFPDCTP--CHQC 1182
Score = 180 bits (439), Expect = 7e-44
Identities = 124/364 (34%), Positives = 159/364 (43%), Gaps = 47/364 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL-PSGFCVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+CQC G +C +CA G + PSG C PC+C+ C+ TG C +C
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQC-HCFQGVYA 848
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C+ G+ G + C C C N A CD L NCQ G
Sbjct: 849 RQCDRCLPGHWGFPS------CQPCQC------NGHADDCDPVTGECL---NCQDYTMGH 893
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSC--DSINGDCLKCVNNTA 1906
CE C AGYYG D + +GD+C+PC C + Q SC D + L CV +
Sbjct: 894 NCERCLAGYYG---DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ-LACVCDPG 949
Query: 1907 --GAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKC 1958
G+ C+ CA G++G+ + +C C C D CD TG C+ C GE C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 1959 DRCAPDHWGLNTGLGCTPCNC---GIASE-----STQCDDDNGQCRCAKGVTGKQCDQCA 2010
C ++G C C C G E QCD GQC C V G+ CD+CA
Sbjct: 1010 QFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 2011 AGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC 2068
W GCD CNCN +S G CN TGQC+C+PG G C C E + P C
Sbjct: 1070 PNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVEC 1129
Query: 2069 LECD 2072
CD
Sbjct: 1130 RACD 1133
Score = 180 bits (438), Expect = 9e-44
Identities = 131/472 (27%), Positives = 194/472 (41%), Gaps = 83/472 (17%)
Query: 188 TNVRLRLLRTKNLLGHLMSVARQDPT-VTRRYFYSIKDI--SIGGRCMCNGHADTCEPAD 244
TN + L + SV + T V R +SI + G C C+ D
Sbjct: 727 TNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCD 786
Query: 245 PAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH-------- 296
P G C+C+ N G CN+C G + + C+PC CH
Sbjct: 787 PNGGQ----CQCRPNVVGRTCNRCAPG--------TFGFGPSGCKPCECHLQGSVNAFCN 834
Query: 297 --TTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHN-------------------TEGI 335
T +C + ++ + G + G C CQ N T G
Sbjct: 835 PVTGQCHCFQGVYARQCDRCLPGHW-GFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-----NCEEE----SGRCECRPEFQ 386
NC +C YY D C+PC C +G +C ++ C C P +
Sbjct: 894 NCERCLAGYYG--DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYI 951
Query: 387 PPDCSSCAYGYFDYP-----NCKPCTC--NLNGTEGEHCTPTDGLC-PCKYNYAGKSCEI 438
C CA GYF P +C+PC C N++ T+ E C G C C Y+ G+ C+
Sbjct: 952 GSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 1011
Query: 439 CEDGYYS----PECKNCECNTVGSV-------SYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
C GYY +C+ C CN +G+V CDK TG C C G+ C++C
Sbjct: 1012 CRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 488 YYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
+ + C PCNC+ + + C++ +GQC C GFGG C +C ++ + +
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD---PDVE 1128
Query: 545 CVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN 594
C C+CDP G + C + G+C C+ G +CD+C+ GY +PDC C+
Sbjct: 1129 CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCH 1180
Score = 172 bits (419), Expect = 2e-41
Identities = 99/328 (30%), Positives = 155/328 (47%), Gaps = 36/328 (10%)
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC---------DVSGSIGST 604
G C C N G C+ C Y+ P C CNC D++ + +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 605 CDDNGLCH-CKSNFDGAKCDTCREQFYNYPA--------CEECNCDP-----RGVTASFA 650
G+C C+ N G C+ C+ +Y +P CE C CDP G+ S+
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
+ C+CK V+G C+ CK +++L +PFGC+ C CN GT+ C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 711 SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSR 770
+G C CK+ V + CDQCL + L +ND+ GC CDCD+GG+++N+C +GQC C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
Query: 771 VEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSGP--VRYRNSEEVFPEYSWKGYVVFSLL 828
+ GR+C++ +YF TL + YE E+ G V + ++ P ++ G+V
Sbjct: 535 MIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEG 594
Query: 829 QNEVINIIQITKSSLYRMVLKYANPLRD 856
I I S Y ++++Y L D
Sbjct: 595 AYLEFFIDNIPYSMEYDILIRYEPQLPD 622
Score = 147 bits (355), Expect = 1e-33
Identities = 95/287 (33%), Positives = 131/287 (45%), Gaps = 36/287 (12%)
Query: 1765 CQCNGHSDQCDVNTGI-----------CLNCADNTIGDHCEFCMSGYHG----DATVGTP 1809
C C GH+ +C G C+ C NT G +CE CM YH A
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 1810 RDCLICACPMPYPSNNFALSCDLSE-NGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTD 1867
C C C S +F ++ L+ N S C+ CQ G CE C YY PE D
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE-RD 388
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDS--------INGDCLKCVNNTAGAACNLCAPGFYG 1919
+ ++C+ C C Q+ G CDS I G C +C N G C++C GFY
Sbjct: 389 IRDPNFCERCTCDP-AGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYD 446
Query: 1920 DAIFSK-NCTACICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL-G 1973
+ C +C C+ G CDS TG C C+ V G+ CD+C P+HWGL+ L G
Sbjct: 447 LSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDG 506
Query: 1974 CTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD 2019
C PC+C + + C ++GQC C + G+QC++ G++ T D
Sbjct: 507 CRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLD 553
Score = 138 bits (334), Expect = 3e-31
Identities = 91/294 (30%), Positives = 136/294 (46%), Gaps = 57/294 (19%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY----R 346
C C+ H +EC +E ++ G G C+ C+HNT+G+NC C Y+ R
Sbjct: 271 CFCYGHASECAPVDGFNE-----EVEGMVHG--HCM-CRHNTKGLNCELCMDFYHDLPWR 322
Query: 347 PYGKRWDELDVCQPCQCDPH-----------FSTGNCEEESGRCE-CRPEFQPPDCSSCA 394
P R + C+ C C+ H +TGN G C+ C+ +C C
Sbjct: 323 PAEGR--NSNACKKCNCNEHSISCHFDMAVYLATGNVS--GGVCDDCQHNTMGRNCEQCK 378
Query: 395 YGYFDYPN--------CKPCTCNLNGTEGEH-CTP-TD-------GLCPCKYNYAGKSCE 437
Y+ +P C+ CTC+ G++ E C TD G C CK N G+ C+
Sbjct: 379 PFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCD 438
Query: 438 ICEDGYY--SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
+C++G+Y S E CK+C CN +G++ CD TG C CK +G+ C+QC ++
Sbjct: 439 VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHW 498
Query: 490 NYPT----CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
C+PC+CD G + C SGQC C+ G +C++ GYY L
Sbjct: 499 GLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATL 552
Score = 138 bits (333), Expect = 5e-31
Identities = 86/260 (33%), Positives = 119/260 (45%), Gaps = 43/260 (16%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYY----MQVLGRERQ-CVPCNC---------DPTGSTS 557
V G C+C+ G C+ C+ Y+ GR C CNC D +
Sbjct: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
Query: 558 TSCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIG-STCDD 607
T + G C+ C N G C+QC P YY++P+ C C CD +GS CD
Sbjct: 354 TGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
Query: 608 ---------NGLCHCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFAGCG 653
G C CK N +G CD C+E FY+ + C+ C C+P G C
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
S G C CK V G+ C+ C P +W L + GC C+C+L G LN+ +C +SGQ
Sbjct: 474 S-ETGH-CYCKRLVTGQHCDQCLPEHWGLSN-DLDGCRPCDCDLGGALNN--SCFAESGQ 528
Query: 714 CVCKQHVGERQCDQCLDGFY 733
C C+ H+ RQC++ G+Y
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 137 bits (332), Expect = 6e-31
Identities = 83/232 (35%), Positives = 101/232 (43%), Gaps = 27/232 (11%)
Query: 1322 CREAMFSITSEYNSGARPCLC-DFMGSTELE-CNTFGGQC-PCKPNVIGRTCSACRTGYY 1378
C F SE +PC C + + +T+ E C+ G+C C + G C CR GYY
Sbjct: 958 CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
Query: 1379 GFP---NCRPC----------HCP-STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDV 1423
G +CR C HC S CD G C+C NV G+NCDRC P T+
Sbjct: 1018 GDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 1077
Query: 1424 QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCN 1481
GCD CNCN G C +G+C C GR C C + PD C C C+
Sbjct: 1078 GTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCD 1135
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCF-CF 1532
G CDQ+T QC C V G CD C Y + D CT C CF
Sbjct: 1136 PRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD----CTPCHQCF 1183
Score = 132 bits (319), Expect = 2e-29
Identities = 70/205 (34%), Positives = 101/205 (49%), Gaps = 29/205 (14%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASF-----AGC 652
+G C C+ N G C+ C + +++ P AC++CNC+ ++ F
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQE---YNPFGCEQCNCNLAGTLNSLGACNT 709
G+V G C+ GR C CKP Y+ E +P CE+C C+ AG+ N G C++
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE-GICDS 413
Query: 710 K--------SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSI--DNNCD 759
+GQC CK +V CD C +GFY L + D FGC C C+ G+I N CD
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 760 KTTGQCHCHSRVEGRRCDQPIRAHY 784
TG C+C V G+ CDQ + H+
Sbjct: 474 SETGHCYCKRLVTGQHCDQCLPEHW 498
Score = 131 bits (317), Expect = 4e-29
Identities = 77/235 (32%), Positives = 101/235 (42%), Gaps = 30/235 (12%)
Query: 1319 TGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY 1378
T +CR +FSI++ + C CD GS C+ GGQC C+PNV+GRTC+ C G +
Sbjct: 752 TDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTF 811
Query: 1379 GF--PNCRPCHC----PSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
GF C+PC C A C+ G C C + V CDRC P + F C C
Sbjct: 812 GFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP---SCQPCQ 868
Query: 1432 CNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYAFP------DCYQCTC---- 1480
CN G+ C+ +G+C C++ G C+ C+ G+Y P C C C
Sbjct: 869 CN-----GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
Query: 1481 --NRHGTTYDVCDQNTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
R D T Q C C G CD C YF + C C C
Sbjct: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
Score = 126 bits (305), Expect = 1e-27
Identities = 82/255 (32%), Positives = 116/255 (45%), Gaps = 48/255 (18%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTP------ 420
G C CR + +C C Y D P CK C CN +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 421 --TDGLCP-CKYNYAGKSCEICEDGYYS-PE--------CKNCECNTVGSVSY-VCDKLT 467
+ G+C C++N G++CE C+ YY PE C+ C C+ GS + +CD T
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 468 --------GDCTCKSKYSGRTCNQCQAGYYNYPT-----CKPCNCDTSGTEP--SICDDV 512
G C CK G C+ C+ G+Y+ + CK C C+ GT P + CD
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 513 SGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ-CVPCNCDPTGSTSTSCSAD-GKCNCLT 570
+G C CK G CDQCL ++ L + C PC+CD G+ + SC A+ G+C+C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWG--LSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRP 533
Query: 571 NFGGAQCDQCSPGYY 585
+ G QC++ PGYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 125 bits (302), Expect = 3e-27
Identities = 79/244 (32%), Positives = 109/244 (44%), Gaps = 30/244 (12%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNC-----SGNINPQDPGSCDSI 1894
C C+ G CE C Y+ +P + + CK CNC S + + + ++
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1895 NGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD---CDSTT-- 1944
+G C C +NT G C C P +Y I N C C CD G + CDS T
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
Query: 1945 ------GTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC---GIASESTQCDDDNG 1993
G C C+ V GE CD C + L++ GC C C G CD + G
Sbjct: 418 STGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETG 477
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIG 2050
C C + VTG+ CDQC W + D GC C+C+ G ++ C A +GQC C P +IG
Sbjct: 478 HCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
Query: 2051 EKCD 2054
+C+
Sbjct: 538 RQCN 541
Score = 119 bits (287), Expect = 2e-25
Identities = 81/260 (31%), Positives = 115/260 (44%), Gaps = 38/260 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC-----------DV 1776
C C +GL+CE C + ++ LP S C C CN HS C +V
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1777 NTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ G+C +C NT+G +CE C Y H + + P C C C P S N + CD
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCD-PAGSQNEGI-CDSYT 415
Query: 1835 NGS--LIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDP 1888
+ S LI+ C C+ G C+ C G+Y + + CK C C+ G I +P
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG----CKSCACNPLGTIPGGNP 471
Query: 1889 GSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CDS G C C G C+ C P +G + C C CD G + C + +G
Sbjct: 472 --CDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQ 528
Query: 1947 CVCRPGVIGEKCDRCAPDHW 1966
C CRP +IG +C+ P ++
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 116 bits (279), Expect = 2e-24
Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 29/193 (15%)
Query: 1353 NTFGGQCP-CKPNVIGRTCSACRTGYYGFPN--------CRPCHCP-----STAICDDN- 1397
N GG C C+ N +GR C C+ YY P C C C + ICD
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 1398 --------GMCICPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
G C C NVEGE+CD CK Y + + GC C CNPLG + C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPD----CYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+G C C+ V G+ CD C+P H+ + C C C+ G + C + QC C+ ++
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
Query: 1504 RGQACDTCKEEYF 1516
G+ C+ + Y+
Sbjct: 536 IGRQCNEVEPGYY 548
Score = 116 bits (278), Expect = 2e-24
Identities = 75/224 (33%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 1868 LH-TGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
LH TG C+ C+ G+++ CD G C +C N G CN CAPG +G
Sbjct: 766 LHQTGLACE-CDPQGSLS----SVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFG--PSG 817
Query: 1927 CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C G + C+ TG C C GV +CDRC P HWG + C PC C
Sbjct: 818 CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCN--GH 872
Query: 1985 STQCDDDNGQC-RCAKGVTGKQCDQCAAGFWN----YTKDGCDHCNCNTGYSVG------ 2033
+ CD G+C C G C++C AG++ + D C C C G G
Sbjct: 873 ADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARS 932
Query: 2034 -FMCNATGQ--CECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ T Q C C PG IG +CD C + P E C C
Sbjct: 933 CYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Score = 104 bits (250), Expect = 5e-21
Identities = 70/219 (31%), Positives = 94/219 (42%), Gaps = 46/219 (21%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CD---------- 1395
G C C+ N G C C Y+ P C+ C+C +I C
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNF---DVQ--RGCDDCNCNPLGVVGNQLQCEAD 1447
G+C C N G NC++CKP+ + D++ C+ C C+P G N+ C++
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQ-NEGICDSY 414
Query: 1448 S--------GKCACRENVRGRVCDHCVPGHYAFPD-----CYQCTCNRHGTTY--DVCDQ 1492
+ G+C C+ NV G CD C G Y C C CN GT + CD
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T CYCK V GQ CD C E++ L +D DGC C C
Sbjct: 475 ETGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPCDC 512
Score = 96.7 bits (230), Expect = 1e-18
Identities = 58/183 (31%), Positives = 82/183 (44%), Gaps = 26/183 (14%)
Query: 1305 EQCASYNYYISPN----ETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCP 1360
EQC + YY P + C N G +CD T+ GQC
Sbjct: 375 EQCKPF-YYQHPERDIRDPNFCERCTCDPAGSQNEG----ICD--SYTDFSTGLIAGQCR 427
Query: 1361 CKPNVIGRTCSACRTGYYGFPN-----CRPCHC------PSTAICD-DNGMCICPKNVEG 1408
CK NV G C C+ G+Y + C+ C C P CD + G C C + V G
Sbjct: 428 CKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTG 487
Query: 1409 ENCDRCKPYTFNFDVQ-RGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
++CD+C P + GC C+C+ G + N C A+SG+C+CR ++ GR C+ P
Sbjct: 488 QHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNN--SCFAESGQCSCRPHMIGRQCNEVEP 545
Query: 1468 GHY 1470
G+Y
Sbjct: 546 GYY 548
Score = 91.9 bits (218), Expect = 4e-17
Identities = 62/202 (30%), Positives = 87/202 (43%), Gaps = 31/202 (15%)
Query: 591 LSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNY--PACEECNCDPRGVTA 647
L+C CD GS+ S CD N G C C+ N G C+ C + + C+ C C +G
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
+F C V G+ C C V R C+ C P +W C+ C CN C
Sbjct: 831 AF--CNPV-TGQ-CHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCN-----GHADDC 876
Query: 708 NTKSGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDC----DIGGSIDNNC- 758
+ +G+C+ C+ + C++CL G+Y + + D C C C D G +C
Sbjct: 877 DPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGD--HCRPCPCPDGPDSGRQFARSCY 934
Query: 759 -DKTTGQ--CHCHSRVEGRRCD 777
D T Q C C G RCD
Sbjct: 935 QDPVTLQLACVCDPGYIGSRCD 956
Score = 88.6 bits (210), Expect = 4e-16
Identities = 70/220 (31%), Positives = 97/220 (44%), Gaps = 43/220 (19%)
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIF-------SKNCTACICDE------FGMADC 1940
++G C+ C +NT G C LC FY D + S C C C+E F MA
Sbjct: 294 VHGHCM-CRHNTKGLNCELCMD-FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVY 351
Query: 1941 DSTT----GTCV-CRPGVIGEKCDRCAPDHW-----GLNTGLGCTPCNCGIASESTQ--C 1988
+T G C C+ +G C++C P ++ + C C C A + C
Sbjct: 352 LATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
Query: 1989 DDDN--------GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV--GFM 2035
D GQCRC V G+ CD C GF++ + + GC C CN ++ G
Sbjct: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP 471
Query: 2036 CNA-TGQCECLPGVIGEKCDRC-PERWVLIPQ-EGCLECD 2072
C++ TG C C V G+ CD+C PE W L +GC CD
Sbjct: 472 CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCD 511
Score = 88.2 bits (209), Expect = 5e-16
Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 31/166 (18%)
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQ-------RGCDDCNCNPLGV-----VGNQLQC 1444
+G C+C N +G NC+ C + + + C CNCN + + L
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 1445 -EADSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYD-VCDQN 1493
G C C+ N GR C+ C P +Y P+ C +CTC+ G+ + +CD
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
Query: 1494 T--------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T QC CK NV G+ CD CKE +++L ++P GC C C
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCAC 460
Score = 87.4 bits (207), Expect = 9e-16
Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTG 2029
TGL C C+ S S+ CD + GQC+C V G+ C++CA G + + GC C C+
Sbjct: 769 TGLACE-CDPQ-GSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 826
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCDRC-PERWVLIPQEGCLECDSCTD 2076
SV CN TGQC C GV +CDRC P W + C +C+ D
Sbjct: 827 GSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPC-QCNGHAD 874
Score = 80.6 bits (190), Expect = 1e-13
Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
C C+ G+L+S+ C+ GQC C+ +V R C++C G + + GC C+C + G
Sbjct: 773 CECDPQGSLSSV--CDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS---GCKPCECHLQG 827
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPTLHQFQ 792
S++ C+ TGQCHC V R+CD+ + H+ FP+ Q
Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQ 868
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 20/135 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSG---FCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C+C G C+ C EG Y L S C C CN + CD TG C C
Sbjct: 425 QCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKR 483
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRD-CLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
G HC+ C+ + G + D C C C + NN SC +E+G C+C+P
Sbjct: 484 LVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN---SC-FAESG---QCSCRP 533
Query: 1846 GYGGARCEYCAAGYY 1860
G +C GYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 40.3 bits (90), Expect = 0.13
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 8/206 (3%)
Query: 2112 ISNQTELLRPKVAQLKTVDI--GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKL 2169
+ N TE +R +V L V++ + I E + R+++ +ATD +
Sbjct: 1540 LQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASK-SATDVKVTADMVKEA 1598
Query: 2170 AEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIADKDLV 2229
E+AE+ A ++ ++A E ++ +L T +E S+ + L A Q R ++++
Sbjct: 1599 LEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIE-SETAASEETLFNASQ-RISELERNVE 1656
Query: 2230 PKKQQAEAVFLNTTTQIERMNFFV-QPVNEQAKASSHRPDLKFESLVNATRELKDKLDDM 2288
K++A A IE++ + V Q + K D K++ + N + ++ D
Sbjct: 1657 ELKRKA-AQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADA 1715
Query: 2289 LEYTDLAQHTAHT-AEELNTKNRLSK 2313
++ Q+ A T + N+K +L K
Sbjct: 1716 RRKAEMLQNEAKTLLAQANSKLQLLK 1741
>M55370-1|AAA59485.1| 1786|Homo sapiens laminin B1 protein.
Length = 1786
Score = 334 bits (820), Expect = 5e-90
Identities = 167/479 (34%), Positives = 243/479 (50%), Gaps = 30/479 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C + C++C GH+ PS C PCQCNGH+D CD TG CLNC D T+G +CE
Sbjct: 839 QCHCFQGVYARQCDRCLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 1795 FCMSGYHGDATVGTPRDCLICACP-MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++GY+GD +G+ C C CP P FA SC ++C C PGY G+RC+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA+GY+G P + G C+PC C NI+ DP +CD G CLKC+ +T G C C
Sbjct: 957 DCASGYFGNPSE----VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
Query: 1914 APGFYGDAIFSKNCTACICDEFGM---------ADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
G+YGDA+ ++C C+C+ G CD TG C+C P VIG+ CDRCAP+
Sbjct: 1013 RFGYYGDAL-RQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 1965 HWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH 2023
W L +G GC PCNC A S C++ GQC+C G G+ C +C FW C
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRA 1131
Query: 2024 CNCN-TGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSV 2082
C+C+ G +TGQC C+ GV G +CD+C + + + C C C F++
Sbjct: 1132 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD-CTPCHQC-----FAL 1185
Query: 2083 ED-LSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTV----DIGEVTSS 2137
D + A L N T F +KA + + + + + KV+++K + E +
Sbjct: 1186 WDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKN 1245
Query: 2138 IKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVAD 2196
I L A+ L++ + ++S + + L +++ A VK +A+
Sbjct: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAE 1304
Score = 241 bits (591), Expect = 3e-62
Identities = 137/466 (29%), Positives = 230/466 (49%), Gaps = 46/466 (9%)
Query: 50 YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDY 109
+A + + WWQS G++ V + +DL EFH ++ + + RP ++E+S+D+
Sbjct: 103 FAPNRLKIWWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTF-KTFRPAAMLIERSSDF 156
Query: 110 GKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR 169
GKT+ ++YF+ DCE F S P+ K D +IC + YS I P +GE+ L+
Sbjct: 157 GKTWGVYRYFA---YDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPA 213
Query: 170 PSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGG 229
++ + Q + TN+R++ ++ L +L+ +R + + +Y+Y++ D+ + G
Sbjct: 214 FKIEDPYSPRI-QNLLKITNLRIKFVKLHTLGDNLLD-SRME--IREKYYYAVYDMVVRG 269
Query: 230 RCMCNGHADTCEPADPAGN-LNILV---CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
C C GHA C P D + +V C C+HNT G C C + WR ++ +
Sbjct: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
+C+ CNC+ H+ C +D +++ + GG C +CQHNT G NC +C+P YY
Sbjct: 330 NACKKCNCNEHSISCHFD-------MAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYY 382
Query: 346 RPYGKRWDELDVCQPCQCDPHFS--TGNCEEE--------SGRCECRPEFQPPDCSSCAY 395
+ + + + C+ C CDP S G C+ +G+C C+ + C C
Sbjct: 383 QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKE 442
Query: 396 GYFDYPN-----CKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--- 445
G++D + CK C CN GT G C G C CK G+ C+ C ++
Sbjct: 443 GFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSN 502
Query: 446 --PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
C+ C+C+ G+++ C +G C+C+ GR CN+ + GYY
Sbjct: 503 DLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 239 bits (584), Expect = 2e-61
Identities = 137/408 (33%), Positives = 195/408 (47%), Gaps = 41/408 (10%)
Query: 406 CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--PE-CKNCECNTVGSVSYV 462
C C+ G+ C P G C C+ N G++C C G + P CK CEC+ GSV+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 463 CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
C+ +TG C C R C++C G++ +P+C+PC C+ + CD V+G+C+ C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADD---CDPVTGECLNCQDY 889
Query: 522 FGGPRCDQCLSGYYMQ-VLGRERQCVPCNCDPTGSTS-----TSCSADG-----KCNCLT 570
G C++CL+GYY ++G C PC C P G S SC D C C
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDP 948
Query: 571 NFGGAQCDQCSPGYYKYP-----DCLSCNC--DVSGSIGSTCD-DNGLC-HCKSNFDGAK 621
+ G++CD C+ GY+ P C C C ++ + CD + G C C + +G
Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 622 CDTCREQFYN---YPACEECNCDPRGVT---ASFAGCGSVPAGELCQCKDRVQGRICNDC 675
C CR +Y C +C C+ G + + C A C C V G+ C+ C
Sbjct: 1009 CQFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRC 1068
Query: 676 KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRL 735
P W L + GC+ CNCN A + +CN +GQC C G R C +C + F+
Sbjct: 1069 APNTWQLA--SGTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFW-- 1122
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
DV C CDCD G CD++TGQC C VEG RCD+ R +
Sbjct: 1123 GDPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY 1169
Score = 227 bits (554), Expect = 8e-58
Identities = 140/424 (33%), Positives = 191/424 (45%), Gaps = 55/424 (12%)
Query: 361 CQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGEH 417
C+CDP S + C+ G+C+CRP C+ CA G F + CKPC C+L G+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
C P G C C + C+ C G++ P C+ C+CN G CD +TG+C C+
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN--GHAD-DCDPVTGECLNCQDY 889
Query: 476 YSGRTCNQCQAGYYNYPT------CKPCNC----DTSGTEPSIC--DDVSGQ--CICKAG 521
G C +C AGYY P C+PC C D+ C D V+ Q C+C G
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 949
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQC 577
+ G RCD C SGY+ C PC C T+ + D G+C CL + G C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 578 DQCSPGYY---KYPDCLSCNCDVSGSI-----GSTCD---DNGLCHCKSNFDGAKCDTCR 626
C GYY DC C C+ G++ GS C G C C N G CD C
Sbjct: 1010 QFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 627 E---QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
Q + C+ CNC+ SF + G+ CQC GR C++C+ L+W
Sbjct: 1070 PNTWQLASGTGCDPCNCN---AAHSFGPSCNEFTGQ-CQCMPGFGGRTCSECQELFWGDP 1125
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVF-G 742
+ C C+C+ G C+ +GQCVC + V +CD+C G+ + VF
Sbjct: 1126 DVE---CRACDCDPRGI--ETPQCDQSTGQCVCVEGVEGPRCDKCTRGY-----SGVFPD 1175
Query: 743 CTEC 746
CT C
Sbjct: 1176 CTPC 1179
Score = 202 bits (492), Expect = 3e-50
Identities = 129/414 (31%), Positives = 185/414 (44%), Gaps = 62/414 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRP-TY-YRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGR 378
GG+C C+ N G CN+C P T+ + P G C+PC+C S C +G+
Sbjct: 789 GGQC-QCRPNVVGRTCNRCAPGTFGFGPSG--------CKPCECHLQGSVNAFCNPVTGQ 839
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCE 437
C C C C G++ +P+C+PC CN + C P G C C+ G +CE
Sbjct: 840 CHCFQGVYARQCDRCLPGHWGFPSCQPCQCN---GHADDCDPVTGECLNCQDYTMGHNCE 896
Query: 438 ICEDGYY-------SPECKNCEC----NTVGSVSYVC--DKLTGD--CTCKSKYSGRTCN 482
C GYY C+ C C ++ + C D +T C C Y G C+
Sbjct: 897 RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Query: 483 QCQAGYYNYP-----TCKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGY 534
C +GY+ P +C+PC C + T+P CD +G+C+ C G C C GY
Sbjct: 957 DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCS--------ADGKCNCLTNFGGAQCDQCSPGYYK 586
Y L + C C C+ G+ C+ A G+C CL N G CD+C+P ++
Sbjct: 1017 YGDAL--RQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQ 1074
Query: 587 YPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
C CNC+ + S G +C++ G C C F G C C+E F+ P C C+C
Sbjct: 1075 LASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDC 1134
Query: 641 DPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL-QEYNPFGCEQC 693
DPRG+ C G+ C C + V+G C+ C Y + + P C QC
Sbjct: 1135 DPRGIET--PQCDQ-STGQ-CVCVEGVEGPRCDKCTRGYSGVFPDCTP--CHQC 1182
Score = 180 bits (439), Expect = 7e-44
Identities = 124/364 (34%), Positives = 159/364 (43%), Gaps = 47/364 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL-PSGFCVPCQCNGHSDQ---CDVNTGICLNCADNTIG 1790
+CQC G +C +CA G + PSG C PC+C+ C+ TG C +C
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQC-HCFQGVYA 848
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C+ G+ G + C C C N A CD L NCQ G
Sbjct: 849 RQCDRCLPGHWGFPS------CQPCQC------NGHADDCDPVTGECL---NCQDYTMGH 893
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNC--SGNINPQDPGSC--DSINGDCLKCVNNTA 1906
CE C AGYYG D + +GD+C+PC C + Q SC D + L CV +
Sbjct: 894 NCERCLAGYYG---DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ-LACVCDPG 949
Query: 1907 --GAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKC 1958
G+ C+ CA G++G+ + +C C C D CD TG C+ C GE C
Sbjct: 950 YIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 1959 DRCAPDHWGLNTGLGCTPCNC---GIASE-----STQCDDDNGQCRCAKGVTGKQCDQCA 2010
C ++G C C C G E QCD GQC C V G+ CD+CA
Sbjct: 1010 QFCRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Query: 2011 AGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC 2068
W GCD CNCN +S G CN TGQC+C+PG G C C E + P C
Sbjct: 1070 PNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVEC 1129
Query: 2069 LECD 2072
CD
Sbjct: 1130 RACD 1133
Score = 180 bits (438), Expect = 9e-44
Identities = 131/472 (27%), Positives = 194/472 (41%), Gaps = 83/472 (17%)
Query: 188 TNVRLRLLRTKNLLGHLMSVARQDPT-VTRRYFYSIKDI--SIGGRCMCNGHADTCEPAD 244
TN + L + SV + T V R +SI + G C C+ D
Sbjct: 727 TNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCD 786
Query: 245 PAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH-------- 296
P G C+C+ N G CN+C G + + C+PC CH
Sbjct: 787 PNGGQ----CQCRPNVVGRTCNRCAPG--------TFGFGPSGCKPCECHLQGSVNAFCN 834
Query: 297 --TTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHN-------------------TEGI 335
T +C + ++ + G + G C CQ N T G
Sbjct: 835 PVTGQCHCFQGVYARQCDRCLPGHW-GFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-----NCEEE----SGRCECRPEFQ 386
NC +C YY D C+PC C +G +C ++ C C P +
Sbjct: 894 NCERCLAGYYG--DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYI 951
Query: 387 PPDCSSCAYGYFDYP-----NCKPCTC--NLNGTEGEHCTPTDGLC-PCKYNYAGKSCEI 438
C CA GYF P +C+PC C N++ T+ E C G C C Y+ G+ C+
Sbjct: 952 GSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF 1011
Query: 439 CEDGYYS----PECKNCECNTVGSV-------SYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
C GYY +C+ C CN +G+V CDK TG C C G+ C++C
Sbjct: 1012 CRFGYYGDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN 1071
Query: 488 YYNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
+ + C PCNC+ + + C++ +GQC C GFGG C +C ++ + +
Sbjct: 1072 TWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD---PDVE 1128
Query: 545 CVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN 594
C C+CDP G + C + G+C C+ G +CD+C+ GY +PDC C+
Sbjct: 1129 CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCH 1180
Score = 172 bits (419), Expect = 2e-41
Identities = 99/328 (30%), Positives = 155/328 (47%), Gaps = 36/328 (10%)
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC---------DVSGSIGST 604
G C C N G C+ C Y+ P C CNC D++ + +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 605 CDDNGLCH-CKSNFDGAKCDTCREQFYNYPA--------CEECNCDP-----RGVTASFA 650
G+C C+ N G C+ C+ +Y +P CE C CDP G+ S+
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
+ C+CK V+G C+ CK +++L +PFGC+ C CN GT+ C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 711 SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSR 770
+G C CK+ V + CDQCL + L +ND+ GC CDCD+GG+++N+C +GQC C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
Query: 771 VEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSGP--VRYRNSEEVFPEYSWKGYVVFSLL 828
+ GR+C++ +YF TL + YE E+ G V + ++ P ++ G+V
Sbjct: 535 MIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEG 594
Query: 829 QNEVINIIQITKSSLYRMVLKYANPLRD 856
I I S Y ++++Y L D
Sbjct: 595 AYLEFFIDNIPYSMEYDILIRYEPQLPD 622
Score = 147 bits (355), Expect = 1e-33
Identities = 95/287 (33%), Positives = 131/287 (45%), Gaps = 36/287 (12%)
Query: 1765 CQCNGHSDQCDVNTGI-----------CLNCADNTIGDHCEFCMSGYHG----DATVGTP 1809
C C GH+ +C G C+ C NT G +CE CM YH A
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 1810 RDCLICACPMPYPSNNFALSCDLSE-NGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTD 1867
C C C S +F ++ L+ N S C+ CQ G CE C YY PE D
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE-RD 388
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDS--------INGDCLKCVNNTAGAACNLCAPGFYG 1919
+ ++C+ C C Q+ G CDS I G C +C N G C++C GFY
Sbjct: 389 IRDPNFCERCTCDP-AGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYD 446
Query: 1920 DAIFSK-NCTACICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL-G 1973
+ C +C C+ G CDS TG C C+ V G+ CD+C P+HWGL+ L G
Sbjct: 447 LSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDG 506
Query: 1974 CTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD 2019
C PC+C + + C ++GQC C + G+QC++ G++ T D
Sbjct: 507 CRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLD 553
Score = 138 bits (334), Expect = 3e-31
Identities = 91/294 (30%), Positives = 136/294 (46%), Gaps = 57/294 (19%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY----R 346
C C+ H +EC +E ++ G G C+ C+HNT+G+NC C Y+ R
Sbjct: 271 CFCYGHASECAPVDGFNE-----EVEGMVHG--HCM-CRHNTKGLNCELCMDFYHDLPWR 322
Query: 347 PYGKRWDELDVCQPCQCDPH-----------FSTGNCEEESGRCE-CRPEFQPPDCSSCA 394
P R + C+ C C+ H +TGN G C+ C+ +C C
Sbjct: 323 PAEGR--NSNACKKCNCNEHSISCHFDMAVYLATGNVS--GGVCDDCQHNTMGRNCEQCK 378
Query: 395 YGYFDYPN--------CKPCTCNLNGTEGEH-CTP-TD-------GLCPCKYNYAGKSCE 437
Y+ +P C+ CTC+ G++ E C TD G C CK N G+ C+
Sbjct: 379 PFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCD 438
Query: 438 ICEDGYY--SPE----CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
+C++G+Y S E CK+C CN +G++ CD TG C CK +G+ C+QC ++
Sbjct: 439 VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHW 498
Query: 490 NYPT----CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
C+PC+CD G + C SGQC C+ G +C++ GYY L
Sbjct: 499 GLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATL 552
Score = 138 bits (333), Expect = 5e-31
Identities = 86/260 (33%), Positives = 119/260 (45%), Gaps = 43/260 (16%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYY----MQVLGRERQ-CVPCNC---------DPTGSTS 557
V G C+C+ G C+ C+ Y+ GR C CNC D +
Sbjct: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353
Query: 558 TSCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIG-STCDD 607
T + G C+ C N G C+QC P YY++P+ C C CD +GS CD
Sbjct: 354 TGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
Query: 608 ---------NGLCHCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFAGCG 653
G C CK N +G CD C+E FY+ + C+ C C+P G C
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
S G C CK V G+ C+ C P +W L + GC C+C+L G LN+ +C +SGQ
Sbjct: 474 S-ETGH-CYCKRLVTGQHCDQCLPEHWGLSN-DLDGCRPCDCDLGGALNN--SCFAESGQ 528
Query: 714 CVCKQHVGERQCDQCLDGFY 733
C C+ H+ RQC++ G+Y
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 137 bits (332), Expect = 6e-31
Identities = 83/232 (35%), Positives = 101/232 (43%), Gaps = 27/232 (11%)
Query: 1322 CREAMFSITSEYNSGARPCLC-DFMGSTELE-CNTFGGQC-PCKPNVIGRTCSACRTGYY 1378
C F SE +PC C + + +T+ E C+ G+C C + G C CR GYY
Sbjct: 958 CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
Query: 1379 GFP---NCRPC----------HCP-STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDV 1423
G +CR C HC S CD G C+C NV G+NCDRC P T+
Sbjct: 1018 GDALRQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 1077
Query: 1424 QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTCN 1481
GCD CNCN G C +G+C C GR C C + PD C C C+
Sbjct: 1078 GTGCDPCNCNAAHSFGP--SCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCD 1135
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCF-CF 1532
G CDQ+T QC C V G CD C Y + D CT C CF
Sbjct: 1136 PRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD----CTPCHQCF 1183
Score = 132 bits (319), Expect = 2e-29
Identities = 70/205 (34%), Positives = 101/205 (49%), Gaps = 29/205 (14%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASF-----AGC 652
+G C C+ N G C+ C + +++ P AC++CNC+ ++ F
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQE---YNPFGCEQCNCNLAGTLNSLGACNT 709
G+V G C+ GR C CKP Y+ E +P CE+C C+ AG+ N G C++
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE-GICDS 413
Query: 710 K--------SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSI--DNNCD 759
+GQC CK +V CD C +GFY L + D FGC C C+ G+I N CD
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 760 KTTGQCHCHSRVEGRRCDQPIRAHY 784
TG C+C V G+ CDQ + H+
Sbjct: 474 SETGHCYCKRLVTGQHCDQCLPEHW 498
Score = 131 bits (317), Expect = 4e-29
Identities = 77/235 (32%), Positives = 101/235 (42%), Gaps = 30/235 (12%)
Query: 1319 TGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY 1378
T +CR +FSI++ + C CD GS C+ GGQC C+PNV+GRTC+ C G +
Sbjct: 752 TDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTF 811
Query: 1379 GF--PNCRPCHC----PSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN 1431
GF C+PC C A C+ G C C + V CDRC P + F C C
Sbjct: 812 GFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP---SCQPCQ 868
Query: 1432 CNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYAFP------DCYQCTC---- 1480
CN G+ C+ +G+C C++ G C+ C+ G+Y P C C C
Sbjct: 869 CN-----GHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
Query: 1481 --NRHGTTYDVCDQNTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
R D T Q C C G CD C YF + C C C
Sbjct: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
Score = 126 bits (305), Expect = 1e-27
Identities = 82/255 (32%), Positives = 116/255 (45%), Gaps = 48/255 (18%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTP------ 420
G C CR + +C C Y D P CK C CN +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 421 --TDGLCP-CKYNYAGKSCEICEDGYYS-PE--------CKNCECNTVGSVSY-VCDKLT 467
+ G+C C++N G++CE C+ YY PE C+ C C+ GS + +CD T
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 468 --------GDCTCKSKYSGRTCNQCQAGYYNYPT-----CKPCNCDTSGTEP--SICDDV 512
G C CK G C+ C+ G+Y+ + CK C C+ GT P + CD
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 513 SGQCICKAGFGGPRCDQCLSGYYMQVLGRERQ-CVPCNCDPTGSTSTSCSAD-GKCNCLT 570
+G C CK G CDQCL ++ L + C PC+CD G+ + SC A+ G+C+C
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWG--LSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRP 533
Query: 571 NFGGAQCDQCSPGYY 585
+ G QC++ PGYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 125 bits (302), Expect = 3e-27
Identities = 79/244 (32%), Positives = 109/244 (44%), Gaps = 30/244 (12%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNC-----SGNINPQDPGSCDSI 1894
C C+ G CE C Y+ +P + + CK CNC S + + + ++
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1895 NGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD---CDSTT-- 1944
+G C C +NT G C C P +Y I N C C CD G + CDS T
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDF 417
Query: 1945 ------GTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC---GIASESTQCDDDNG 1993
G C C+ V GE CD C + L++ GC C C G CD + G
Sbjct: 418 STGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETG 477
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNA-TGQCECLPGVIG 2050
C C + VTG+ CDQC W + D GC C+C+ G ++ C A +GQC C P +IG
Sbjct: 478 HCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
Query: 2051 EKCD 2054
+C+
Sbjct: 538 RQCN 541
Score = 119 bits (287), Expect = 2e-25
Identities = 81/260 (31%), Positives = 115/260 (44%), Gaps = 38/260 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC-----------DV 1776
C C +GL+CE C + ++ LP S C C CN HS C +V
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 1777 NTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ G+C +C NT+G +CE C Y H + + P C C C P S N + CD
Sbjct: 358 SGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCD-PAGSQNEGI-CDSYT 415
Query: 1835 NGS--LIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDP 1888
+ S LI+ C C+ G C+ C G+Y + + CK C C+ G I +P
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG----CKSCACNPLGTIPGGNP 471
Query: 1889 GSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CDS G C C G C+ C P +G + C C CD G + C + +G
Sbjct: 472 --CDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQ 528
Query: 1947 CVCRPGVIGEKCDRCAPDHW 1966
C CRP +IG +C+ P ++
Sbjct: 529 CSCRPHMIGRQCNEVEPGYY 548
Score = 116 bits (279), Expect = 2e-24
Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 29/193 (15%)
Query: 1353 NTFGGQCP-CKPNVIGRTCSACRTGYYGFPN--------CRPCHCP-----STAICDDN- 1397
N GG C C+ N +GR C C+ YY P C C C + ICD
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415
Query: 1398 --------GMCICPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
G C C NVEGE+CD CK Y + + GC C CNPLG + C+++
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPD----CYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+G C C+ V G+ CD C+P H+ + C C C+ G + C + QC C+ ++
Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHM 535
Query: 1504 RGQACDTCKEEYF 1516
G+ C+ + Y+
Sbjct: 536 IGRQCNEVEPGYY 548
Score = 116 bits (278), Expect = 2e-24
Identities = 75/224 (33%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 1868 LH-TGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
LH TG C+ C+ G+++ CD G C +C N G CN CAPG +G
Sbjct: 766 LHQTGLACE-CDPQGSLS----SVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFG--PSG 817
Query: 1927 CTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C G + C+ TG C C GV +CDRC P HWG + C PC C
Sbjct: 818 CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCN--GH 872
Query: 1985 STQCDDDNGQC-RCAKGVTGKQCDQCAAGFWN----YTKDGCDHCNCNTGYSVG------ 2033
+ CD G+C C G C++C AG++ + D C C C G G
Sbjct: 873 ADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARS 932
Query: 2034 -FMCNATGQ--CECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+ T Q C C PG IG +CD C + P E C C
Sbjct: 933 CYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Score = 104 bits (250), Expect = 5e-21
Identities = 70/219 (31%), Positives = 94/219 (42%), Gaps = 46/219 (21%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CD---------- 1395
G C C+ N G C C Y+ P C+ C+C +I C
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNF---DVQ--RGCDDCNCNPLGVVGNQLQCEAD 1447
G+C C N G NC++CKP+ + D++ C+ C C+P G N+ C++
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQ-NEGICDSY 414
Query: 1448 S--------GKCACRENVRGRVCDHCVPGHYAFPD-----CYQCTCNRHGTTY--DVCDQ 1492
+ G+C C+ NV G CD C G Y C C CN GT + CD
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T CYCK V GQ CD C E++ L +D DGC C C
Sbjct: 475 ETGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPCDC 512
Score = 96.7 bits (230), Expect = 1e-18
Identities = 58/183 (31%), Positives = 82/183 (44%), Gaps = 26/183 (14%)
Query: 1305 EQCASYNYYISPN----ETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCP 1360
EQC + YY P + C N G +CD T+ GQC
Sbjct: 375 EQCKPF-YYQHPERDIRDPNFCERCTCDPAGSQNEG----ICD--SYTDFSTGLIAGQCR 427
Query: 1361 CKPNVIGRTCSACRTGYYGFPN-----CRPCHC------PSTAICD-DNGMCICPKNVEG 1408
CK NV G C C+ G+Y + C+ C C P CD + G C C + V G
Sbjct: 428 CKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTG 487
Query: 1409 ENCDRCKPYTFNFDVQ-RGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
++CD+C P + GC C+C+ G + N C A+SG+C+CR ++ GR C+ P
Sbjct: 488 QHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNN--SCFAESGQCSCRPHMIGRQCNEVEP 545
Query: 1468 GHY 1470
G+Y
Sbjct: 546 GYY 548
Score = 91.9 bits (218), Expect = 4e-17
Identities = 62/202 (30%), Positives = 87/202 (43%), Gaps = 31/202 (15%)
Query: 591 LSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNY--PACEECNCDPRGVTA 647
L+C CD GS+ S CD N G C C+ N G C+ C + + C+ C C +G
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
+F C V G+ C C V R C+ C P +W C+ C CN C
Sbjct: 831 AF--CNPV-TGQ-CHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCN-----GHADDC 876
Query: 708 NTKSGQCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDC----DIGGSIDNNC- 758
+ +G+C+ C+ + C++CL G+Y + + D C C C D G +C
Sbjct: 877 DPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGD--HCRPCPCPDGPDSGRQFARSCY 934
Query: 759 -DKTTGQ--CHCHSRVEGRRCD 777
D T Q C C G RCD
Sbjct: 935 QDPVTLQLACVCDPGYIGSRCD 956
Score = 88.6 bits (210), Expect = 4e-16
Identities = 70/220 (31%), Positives = 97/220 (44%), Gaps = 43/220 (19%)
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIF-------SKNCTACICDE------FGMADC 1940
++G C+ C +NT G C LC FY D + S C C C+E F MA
Sbjct: 294 VHGHCM-CRHNTKGLNCELCMD-FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVY 351
Query: 1941 DSTT----GTCV-CRPGVIGEKCDRCAPDHW-----GLNTGLGCTPCNCGIASESTQ--C 1988
+T G C C+ +G C++C P ++ + C C C A + C
Sbjct: 352 LATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
Query: 1989 DDDN--------GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSV--GFM 2035
D GQCRC V G+ CD C GF++ + + GC C CN ++ G
Sbjct: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNP 471
Query: 2036 CNA-TGQCECLPGVIGEKCDRC-PERWVLIPQ-EGCLECD 2072
C++ TG C C V G+ CD+C PE W L +GC CD
Sbjct: 472 CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCD 511
Score = 88.2 bits (209), Expect = 5e-16
Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 31/166 (18%)
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQ-------RGCDDCNCNPLGV-----VGNQLQC 1444
+G C+C N +G NC+ C + + + C CNCN + + L
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 1445 -EADSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYD-VCDQN 1493
G C C+ N GR C+ C P +Y P+ C +CTC+ G+ + +CD
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
Query: 1494 T--------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T QC CK NV G+ CD CKE +++L ++P GC C C
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCAC 460
Score = 87.4 bits (207), Expect = 9e-16
Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTG 2029
TGL C C+ S S+ CD + GQC+C V G+ C++CA G + + GC C C+
Sbjct: 769 TGLACE-CDPQ-GSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 826
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCDRC-PERWVLIPQEGCLECDSCTD 2076
SV CN TGQC C GV +CDRC P W + C +C+ D
Sbjct: 827 GSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPC-QCNGHAD 874
Score = 80.6 bits (190), Expect = 1e-13
Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
C C+ G+L+S+ C+ GQC C+ +V R C++C G + + GC C+C + G
Sbjct: 773 CECDPQGSLSSV--CDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS---GCKPCECHLQG 827
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPTLHQFQ 792
S++ C+ TGQCHC V R+CD+ + H+ FP+ Q
Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQ 868
Score = 58.8 bits (136), Expect = 3e-07
Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 20/135 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSG---FCVPCQCN-----GHSDQCDVNTGICLNCAD 1786
+C+C G C+ C EG Y L S C C CN + CD TG C C
Sbjct: 425 QCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKR 483
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRD-CLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
G HC+ C+ + G + D C C C + NN SC +E+G C+C+P
Sbjct: 484 LVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN---SC-FAESG---QCSCRP 533
Query: 1846 GYGGARCEYCAAGYY 1860
G +C GYY
Sbjct: 534 HMIGRQCNEVEPGYY 548
Score = 40.3 bits (90), Expect = 0.13
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 8/206 (3%)
Query: 2112 ISNQTELLRPKVAQLKTVDI--GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKL 2169
+ N TE +R +V L V++ + I E + R+++ +ATD +
Sbjct: 1540 LQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASK-SATDVKVTADMVKEA 1598
Query: 2170 AEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIADKDLV 2229
E+AE+ A ++ ++A E ++ +L T +E S+ + L A Q R ++++
Sbjct: 1599 LEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIE-SETAASEETLFNASQ-RISELERNVE 1656
Query: 2230 PKKQQAEAVFLNTTTQIERMNFFV-QPVNEQAKASSHRPDLKFESLVNATRELKDKLDDM 2288
K++A A IE++ + V Q + K D K++ + N + ++ D
Sbjct: 1657 ELKRKA-AQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADA 1715
Query: 2289 LEYTDLAQHTAHT-AEELNTKNRLSK 2313
++ Q+ A T + N+K +L K
Sbjct: 1716 RRKAEMLQNEAKTLLAQANSKLQLLK 1741
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 320 bits (785), Expect = 8e-86
Identities = 197/549 (35%), Positives = 255/549 (46%), Gaps = 55/549 (10%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPS-TAICD-DNGMCI-CPKNVEG 1408
QC C P G +C C TGY P+ C C C + C+ + G C C + EG
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQLQ-CEADSG---KC-ACRENVRG 1459
C++C+P + D QRG C C C G C D+ C AC G
Sbjct: 1185 PRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSG 1243
Query: 1460 RVCDHCVPGHYAFPD----CYQ---------CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
R C+ C PG+Y P C + C C+ G+ CD QC CK V G
Sbjct: 1244 RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGL 1302
Query: 1507 ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVD----VLIN 1562
C C+ +F+L NPDGC CFC G T +C+SS YT I + P D L+N
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLIS--THFAPGDFQGFALVN 1360
Query: 1563 --NTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTV 1620
L V + L+ G N + Y+ PE Y G ++ +YGG L YT+
Sbjct: 1361 PQRNSRLTGEFTVEPVPEGAQLSFG-NFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTL 1419
Query: 1621 HYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMP--WTHSVKLSEEEFSTLDGAPV 1678
YT G ++ PDV I G N LV QP + P ++ + EE + DG P
Sbjct: 1420 SYTAGPQGSPLSDPDVQITGNNIMLV---ASQPALQGPERRSYEIMFREEFWRRPDGQPA 1476
Query: 1679 TRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQC 1738
TR+ + AL ++ L IRA++ + S+S V LE+ RA VEEC+C
Sbjct: 1477 TREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRP----RALEVEECRC 1532
Query: 1739 PRAYRGLSCEQCAEGHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
P Y GLSC+ CA G+ R SG C C+CNGHSD C TG C C N G+ CE
Sbjct: 1533 PPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCE 1592
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
C GY+GDAT GTP DC CACP+ P N F+ +C+ G C+PGY G CE
Sbjct: 1593 LCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQ 1652
Query: 1855 CAAGYYGIP 1863
C GY G P
Sbjct: 1653 CGPGYVGNP 1661
Score = 302 bits (741), Expect = 2e-80
Identities = 194/607 (31%), Positives = 268/607 (44%), Gaps = 41/607 (6%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPSTAI-CDD-NGMCI-CPKNVEG 1408
+C C G +C +C + P C C+C A CD G C+ C N EG
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEG 789
Query: 1409 ENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ----CEADS---GKC-ACRENVRGR 1460
C++CK F ++ C P + + C D+ C AC GR
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 849
Query: 1461 VCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ------CYCKTNVRGQACDTCKEE 1514
C+ C PG+ P C CD+ + C CK NV G+ C+ C +
Sbjct: 850 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Query: 1515 YFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVP 1574
F+L NPDGC KCFC G + C+SS ++ A + + P + N H
Sbjct: 910 SFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASE-EPGHFSLTNAAS--THTTNE 966
Query: 1575 ELTNVTVLTVGLNDGVTNGKVAYF-GAPEYYLGKRLTSYGGYLTYTVHYTTR-GDGDAVA 1632
+ + T +G + YF P +LG ++TSYGG L +TV ++ G
Sbjct: 967 GIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHG 1026
Query: 1633 APDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISG 1692
P V++ G N L H+ ++P G P T V E+ + DG P TR+ + AL I
Sbjct: 1027 QPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDT 1086
Query: 1693 LYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAE 1752
L IRASY + E+ +S + +++ V G + A VE+C CP YRG SC+ C
Sbjct: 1087 LLIRASYAQQPAESRVSGISMDVAVPEETGQD----PALEVEQCSCPPGYRGPSCQDCDT 1142
Query: 1753 GHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGT 1808
G+ R PSG C C C+GHS+ C+ TG C C +T G CE C GY+GDA GT
Sbjct: 1143 GYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGT 1202
Query: 1809 PRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDL 1868
P+DC +C C + A +C L +G C PG+ G CE CA GYYG P
Sbjct: 1203 PQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQP 1262
Query: 1869 HTGDYCKPCNCSGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCAP-GFYGDAIFSK 1925
D P N +PQ S CD+ G C +C G C+ C P F+ A
Sbjct: 1263 CQRDSQVPGPIGCNCDPQGSVSSQCDAA-GQC-QCKAQVEGLTCSHCRPHHFHLSASNPD 1320
Query: 1926 NCTACIC 1932
C C C
Sbjct: 1321 GCLPCFC 1327
Score = 217 bits (529), Expect = 8e-55
Identities = 141/434 (32%), Positives = 194/434 (44%), Gaps = 24/434 (5%)
Query: 1511 CKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI----DEMVDWYPVDVLINNTIE 1566
C + +F L+ + C CFCFG T+ C S+ I D+ D+ V+V +
Sbjct: 505 CPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPG 562
Query: 1567 LYPHEDVPELTNVTVLTVGLNDGVTNGKV--AYFGAPEYYLGKRLTSYGGYLTYTVHYT- 1623
P + ++ L D V +++ PE +LG ++ SYGG L Y V Y
Sbjct: 563 TPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYEL 622
Query: 1624 TRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQF 1683
RG + V PDV++ G L+ G V+ SEE + G PV R +
Sbjct: 623 ARGMLEPVQRPDVVLMGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPVQRAEL 682
Query: 1684 MHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYR 1743
+ L ++ + I+ Y LS++ ++ V + RA SVEEC+CP Y
Sbjct: 683 LQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHG----RAHSVEECRCPIGYS 738
Query: 1744 GLSCEQCAEGHYRLPSG----FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSG 1799
GLSCE C R+P G C C CNGH+ CD G CLNC NT G C C +G
Sbjct: 739 GLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAG 798
Query: 1800 YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGY 1859
+ GDA T C C CP S F+ +C L +G C PGY G RCE CA GY
Sbjct: 799 FFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY 858
Query: 1860 YGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG-FY 1918
G P + G C+P N + + GS + +G+ +C NN G CN CA G F+
Sbjct: 859 EGNP----IQPGGKCRPVN-QEIVRCDERGSMGT-SGEACRCKNNVVGRLCNECADGSFH 912
Query: 1919 GDAIFSKNCTACIC 1932
C C C
Sbjct: 913 LSTRNPDGCLKCFC 926
Score = 120 bits (288), Expect = 1e-25
Identities = 72/208 (34%), Positives = 95/208 (45%), Gaps = 26/208 (12%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S+ C C GY G CE C A + +P L T C CNC+G+ + SCD + G
Sbjct: 727 SVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGT---CSGCNCNGHAS-----SCDPVYG 778
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTT--------GT 1946
CL C +NT G CN C GF+GDA+ + +C C C + S T T
Sbjct: 779 HCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 838
Query: 1947 C-VCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIA--SESTQCDDDNGQCRCAKGV 2001
C C PG G +C+ CAP + G + G C P N I E CRC V
Sbjct: 839 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNV 898
Query: 2002 TGKQCDQCAAGFWNYT---KDGCDHCNC 2026
G+ C++CA G ++ + DGC C C
Sbjct: 899 VGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 111 bits (268), Expect = 3e-23
Identities = 67/202 (33%), Positives = 88/202 (43%), Gaps = 32/202 (15%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C+C Y G +C C GY P TC+ C+C C+ +G C C+
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHS---EACEPETGACQGCQHHT 1182
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNC--DPT-GSTSTSC--SADGK--CN-CLTNFG 573
GPRC+QC GYY G + C C C DP G + +C DG C+ C
Sbjct: 1183 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 574 GAQCDQCSPGYYKYPD----C---------LSCNCDVSGSIGSTCDDNGLCHCKSNFDGA 620
G C++C+PGYY P C + CNCD GS+ S CD G C CK+ +G
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 1302
Query: 621 KCDTCREQFYNYPACEECNCDP 642
C CR ++ A C P
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLP 1324
Score = 102 bits (245), Expect = 2e-20
Identities = 72/226 (31%), Positives = 103/226 (45%), Gaps = 41/226 (18%)
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTST 558
+ +G +P++ +V QC C G+ GP C C +GY G C C+C S
Sbjct: 1113 EETGQDPAL--EVE-QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSE 1166
Query: 559 SCSAD-GKCN-CLTNFGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC-- 605
+C + G C C + G +C+QC PGYY DC C C +G TC
Sbjct: 1167 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFL 1226
Query: 606 --DDNGLCH-CKSNFDGAKCDTCREQFYNYPA----CEE---------CNCDPRGVTASF 649
D + C C G C+ C +Y P+ C+ CNCDP+G +S
Sbjct: 1227 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS- 1285
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C + AG+ CQCK +V+G C+ C+P +++L NP GC C C
Sbjct: 1286 -QCDA--AGQ-CQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 101 bits (242), Expect = 5e-20
Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 38/210 (18%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLCP-C 427
E +C C P ++ P C C GY P+ C+ C+C+ E C P G C C
Sbjct: 1122 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGC 1178
Query: 428 KYNYAGKSCEICEDGYYS-------PECKNCEC---NTVGSVSYVCDKLT-GDCTCKS-- 474
+++ G CE C+ GYY +C+ C C G ++ C T G TC +
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 475 -KYSGRTCNQCQAGYYNYPT----CK---------PCNCDTSGTEPSICDDVSGQCICKA 520
+SGR C +C GYY P+ C+ CNCD G+ S C D +GQC CKA
Sbjct: 1239 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAAGQCQCKA 1297
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
G C C ++ C+PC C
Sbjct: 1298 QVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 94.7 bits (225), Expect = 6e-18
Identities = 62/202 (30%), Positives = 88/202 (43%), Gaps = 26/202 (12%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKC-NCLTN 571
+C C G+ G C+ C ++ +V G C CNC+ G S+ G C NC N
Sbjct: 730 ECRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCNCN--GHASSCDPVYGHCLNCQHN 786
Query: 572 FGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC----DDNGLCH-CKSNF 617
G QC++C G++ C C C D S TC D C C +
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 618 DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC---GSV-PAGELCQCKDRVQGRICN 673
G +C++C + P C P V C GS+ +GE C+CK+ V GR+CN
Sbjct: 847 TGRRCESCAPGYEGNPIQPGGKCRP--VNQEIVRCDERGSMGTSGEACRCKNNVVGRLCN 904
Query: 674 DCKPLYWNLQEYNPFGCEQCNC 695
+C ++L NP GC +C C
Sbjct: 905 ECADGSFHLSTRNPDGCLKCFC 926
Score = 87.0 bits (206), Expect = 1e-15
Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C PGY G C+ CA GY + L+ G +C+ C C+G+ + C G C +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGY--TRTGSGLYLG-HCELCECNGHSD-----LCHPETGACSQ 1581
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFS--KNCTACIC-----DEFGMADCDSTTG---TC-VC 1949
C +N AG C LCAPG+YGDA ++C C C + C+S C C
Sbjct: 1582 CQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTAC 1641
Query: 1950 RPGVIGEKCDRCAPDHWG 1967
PG G+ C++C P + G
Sbjct: 1642 EPGYTGQYCEQCGPGYVG 1659
Score = 86.2 bits (204), Expect = 2e-15
Identities = 65/222 (29%), Positives = 93/222 (41%), Gaps = 38/222 (17%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCE-CRPEF 385
+C G +C C Y R + L C+ C C H CE E+G C+ C+
Sbjct: 1127 SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGHSEA--CEPETGACQGCQHHT 1182
Query: 386 QPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE--H-C-TPTDG--LCP-CKYNYA 432
+ P C C GY+ +C+ C C + G+ H C TDG C C ++
Sbjct: 1183 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 433 GKSCEICEDGYY-SPE----CKN---------CECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G+ CE C GYY +P C+ C C+ GSVS CD G C CK++ G
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEG 1301
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
TC+ C+ +++ P C P C ++ QC A
Sbjct: 1302 LTCSHCRPHHFHLSASNPDGC-----LPCFCMGITQQCASSA 1338
Score = 85.0 bits (201), Expect = 5e-15
Identities = 60/215 (27%), Positives = 91/215 (42%), Gaps = 29/215 (13%)
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDS 1942
P++ G ++ + C G +C C G+ ++ C C C A C+
Sbjct: 1112 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA-CEP 1170
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC------GIASESTQCDDD- 1991
TG C C+ G +C++C P ++G T C C C G A+ + D D
Sbjct: 1171 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDG 1230
Query: 1992 NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---------CNCNTGYSVGFMCNAT 2039
+ C C+ G +G+ C++CA G++ G C CNC+ SV C+A
Sbjct: 1231 HPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA 1290
Query: 2040 GQCECLPGVIGEKCDRC-PERWVLIPQ--EGCLEC 2071
GQC+C V G C C P + L +GCL C
Sbjct: 1291 GQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 1325
Score = 84.6 bits (200), Expect = 6e-15
Identities = 68/235 (28%), Positives = 91/235 (38%), Gaps = 42/235 (17%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC G C C + F R+ +C CNC+ H + C DP
Sbjct: 731 CRCPIGYSGLSCESCDAHFT----RVPGGPYLGTCSGCNCNGHASSC--DPVY------- 777
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC-----DPHFS 368
G CLNCQHNTEG CNKC+ ++ K C+PC C FS
Sbjct: 778 ---------GHCLNCQHNTEGPQCNKCKAGFFGDAMKA--TATSCRPCPCPYIDASRRFS 826
Query: 369 TGNCEEESGR--CE-CRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHCTP 420
+ G+ C+ C P + C SCA GY P C+P + +
Sbjct: 827 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMG 886
Query: 421 TDG-LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKS 474
T G C CK N G+ C C DG + +N + G + C ++ CT S
Sbjct: 887 TSGEACRCKNNVVGRLCNECADGSFHLSTRNPD----GCLKCFCMGVSRHCTSSS 937
Score = 83.0 bits (196), Expect = 2e-14
Identities = 58/205 (28%), Positives = 86/205 (41%), Gaps = 26/205 (12%)
Query: 316 NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE 375
+GR +C C G++C C + R G + L C C C+ H S+ C+
Sbjct: 722 HGRAHSVEEC-RCPIGYSGLSCESCDAHFTRVPGGPY--LGTCSGCNCNGHASS--CDPV 776
Query: 376 SGRC-ECRPEFQPPDCSSCAYGYFD------YPNCKPCTC---NLNGTEGEHC-TPTDGL 424
G C C+ + P C+ C G+F +C+PC C + + + C TDG
Sbjct: 777 YGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQ 836
Query: 425 CPCKY---NYAGKSCEICEDGYY-SPECKNCECNTVGSVSYVCDK-----LTGD-CTCKS 474
C Y G+ CE C GY +P +C V CD+ +G+ C CK+
Sbjct: 837 ATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKN 896
Query: 475 KYSGRTCNQCQAGYYNYPTCKPCNC 499
GR CN+C G ++ T P C
Sbjct: 897 NVVGRLCNECADGSFHLSTRNPDGC 921
Score = 81.8 bits (193), Expect = 4e-14
Identities = 56/202 (27%), Positives = 83/202 (41%), Gaps = 23/202 (11%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD------CLSCNCDVSGSIGSTCDD-NGLC-HCKSN 616
+C C + G C+ C + + P C CNC+ S+CD G C +C+ N
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCN---GHASSCDPVYGHCLNCQHN 786
Query: 617 FDGAKCDTCREQFYN------YPACEECNCDPRGVTASFAG-CGSVPAGEL-CQ-CKDRV 667
+G +C+ C+ F+ +C C C + F+ C G+ C C
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 668 QGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
GR C C P Y P G C N + + G+ T C CK +V R C+
Sbjct: 847 TGRRCESCAPGYEG-NPIQPGGKCRPVNQEIV-RCDERGSMGTSGEACRCKNNVVGRLCN 904
Query: 727 QCLDGFYRLQTNDVFGCTECDC 748
+C DG + L T + GC +C C
Sbjct: 905 ECADGSFHLSTRNPDGCLKCFC 926
Score = 78.2 bits (184), Expect = 5e-13
Identities = 69/248 (27%), Positives = 94/248 (37%), Gaps = 52/248 (20%)
Query: 244 DPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYD 303
DPA L + C C GP C C +G+ R +CE C+CH H+ C +
Sbjct: 1118 DPA--LEVEQCSCPPGYRGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--E 1169
Query: 304 PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC 363
PE G C CQH+TEG C +C+P YY +R D CQ C C
Sbjct: 1170 PET----------------GACQGCQHHTEGPRCEQCQPGYYGD-AQRGTPQD-CQLCPC 1211
Query: 364 --DPHF--STGNC---EEESGRCE-CRPEFQPPDCSSCAYGYFDYPN----CK------- 404
DP + C + C+ C P C CA GY+ P+ C+
Sbjct: 1212 YGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 1271
Query: 405 --PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
C C+ G+ C G C CK G +C C ++ N + G +
Sbjct: 1272 PIGCNCDPQGSVSSQCDAA-GQCQCKAQVEGLTCSHCRPHHFHLSASNPD----GCLPCF 1326
Query: 463 CDKLTGDC 470
C +T C
Sbjct: 1327 CMGITQQC 1334
Score = 77.4 bits (182), Expect = 9e-13
Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 1158 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 1206
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + + ++ +G C C G +C +C P YY P
Sbjct: 1207 QLCPCYG-------DPAAGQAAHTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNP 1257
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----- 398
+ + D P C CDP S + + +G+C+C+ + + CS C +F
Sbjct: 1258 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSAS 1317
Query: 399 DYPNCKPCTC 408
+ C PC C
Sbjct: 1318 NPDGCLPCFC 1327
Score = 74.9 bits (176), Expect = 5e-12
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPDCL---SCN-CDVSGSIGSTCDDNGLCH-CKSNFDG 619
+C+C + G C C GY + P L +C C G + + G C C+ + +G
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 620 AKCDTCREQFYNYPA------CEECNC--DPRGVTASFAGCGSVPAGELCQ-CKDRVQGR 670
+C+ C+ +Y C+ C C DP A+ C C GR
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1244
Query: 671 ICNDCKPLYW-NLQEYNPF-------GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C C P Y+ N + P G CNC+ G+++S C+ +GQC CK V
Sbjct: 1245 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS--QCDA-AGQCQCKAQVEG 1301
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDC 748
C C + L ++ GC C C
Sbjct: 1302 LTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 73.7 bits (173), Expect = 1e-11
Identities = 48/146 (32%), Positives = 64/146 (43%), Gaps = 24/146 (16%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGY------FDYPNCKPCTCNLNGTEGEHCTPTDGLCP-C 427
E C C P + C CA GY +C+ C CN + C P G C C
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQC 1582
Query: 428 KYNYAGKSCEICEDGYY------SPE-CKNCEC---NTVGSVSYVCDKLTGD---CT-CK 473
++N AG+ CE+C GYY +PE C+ C C N S C+ L CT C+
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACE 1642
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNC 499
Y+G+ C QC GY P+ + C
Sbjct: 1643 PGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/196 (27%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQ-C 663
C C + G C C + P+ CE C+C P CQ C
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE-------PETGACQGC 1178
Query: 664 KDRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCN---LAGTLNSLGACNTKSGQ-C-VCK 717
+ +G C C+P Y+ + Q P C+ C C AG +T C C
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 718 QHVGERQCDQCLDGFYR--------LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHS 769
R C++C G+Y + + V G C+CD GS+ + CD GQC C +
Sbjct: 1239 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKA 1297
Query: 770 RVEGRRCDQPIRAHYF 785
+VEG C R H+F
Sbjct: 1298 QVEGLTCSH-CRPHHF 1312
Score = 70.5 bits (165), Expect = 1e-10
Identities = 62/197 (31%), Positives = 74/197 (37%), Gaps = 34/197 (17%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGHA +C+P G+ CQHNT GPQCNKC +GF + + SC P
Sbjct: 764 CNCNGHASSCDPV--YGHC----LNCQHNTEGPQCNKCKAGFFGDAMKATAT----SCRP 813
Query: 291 CNCHNHTTECTYDPEID-EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C P ID +R S +G C C G C C P Y G
Sbjct: 814 CPC----------PYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY---EG 860
Query: 350 KRWDELDVCQP-----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
C+P +CD S G E C C+ C+ CA G F
Sbjct: 861 NPIQPGGKCRPVNQEIVRCDERGSMGTSGE---ACRCKNNVVGRLCNECADGSFHLSTRN 917
Query: 405 PCTCNLNGTEG--EHCT 419
P C G HCT
Sbjct: 918 PDGCLKCFCMGVSRHCT 934
Score = 70.5 bits (165), Expect = 1e-10
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 24/144 (16%)
Query: 425 CPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDCT-CKSKY 476
C C Y G SC+ C GY Y C+ CECN S +C TG C+ C+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQCQHNA 1586
Query: 477 SGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSI---CDDVSG---QCI-CKAGFG 523
+G C C GYY T C+PC C + E C+ + +C C+ G+
Sbjct: 1587 AGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYT 1646
Query: 524 GPRCDQCLSGYYMQVLGRERQCVP 547
G C+QC GY + QC+P
Sbjct: 1647 GQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 68.5 bits (160), Expect = 4e-10
Identities = 55/208 (26%), Positives = 75/208 (36%), Gaps = 26/208 (12%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPN---CKPCT-CNLNGTEGEHCTPTDGLC-PCKYNYAG 433
C C + C SC + P C+ CN NG C P G C C++N G
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNG-HASSCDPVYGHCLNCQHNTEG 789
Query: 434 KSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKL----TGDCTCKS---KYSGR 479
C C+ G++ + C+ C C + + D G TC + Y+GR
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 849
Query: 480 TCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD-----VSGQ-CICKAGFGGPRCDQCLSG 533
C C GY P C E CD+ SG+ C CK G C++C G
Sbjct: 850 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Query: 534 YYMQVLGRERQCVPCNCDPTGSTSTSCS 561
+ C+ C C TS S
Sbjct: 910 SFHLSTRNPDGCLKCFCMGVSRHCTSSS 937
Score = 66.9 bits (156), Expect = 1e-09
Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 19/143 (13%)
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
+C C Y G +C C GY + C+ C C+ +C +G C C+
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHS---DLCHPETGACSQCQHN 1585
Query: 522 FGGPRCDQCLSGYYMQVL-GRERQCVPCNC---DPTGSTSTSCSADG----KCN-CLTNF 572
G C+ C GYY G C PC C +P S +C + G +C C +
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 573 GGAQCDQCSPGYYKYPDCLSCNC 595
G C+QC PGY P C
Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 64.9 bits (151), Expect = 5e-09
Identities = 53/197 (26%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 1900 KCVNNTAGAACNLCAPGF--YGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGE 1956
+C +G +C C F + C+ C C+ + CD G C+ C+ G
Sbjct: 732 RCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHA-SSCDPVYGHCLNCQHNTEGP 790
Query: 1957 KCDRCAPDHWG---LNTGLGCTPCNCGIASESTQCDDD-----NGQCRC---AKGVTGKQ 2005
+C++C +G T C PC C S + D +GQ C A G TG++
Sbjct: 791 QCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRR 850
Query: 2006 CDQCAAGF-WNYTKDG--CDHCN-----CNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
C+ CA G+ N + G C N C+ S+G A C C V+G C+ C
Sbjct: 851 CESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEA---CRCKNNVVGRLCNECA 907
Query: 2058 ERWVLIP---QEGCLEC 2071
+ + +GCL+C
Sbjct: 908 DGSFHLSTRNPDGCLKC 924
Score = 62.9 bits (146), Expect = 2e-08
Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN-CGIASESTQCDDDNGQC-RCAKGVTGK 2004
C C PG IG C CAP + +GL C C S C + G C +C G+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGE 1589
Query: 2005 QCDQCAAGFWN----YTKDGCDHCNC---NTGYSVGFMCNATG----QC-ECLPGVIGEK 2052
C+ CA G++ T + C C C N C + G +C C PG G+
Sbjct: 1590 FCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQY 1649
Query: 2053 CDRCPERWV 2061
C++C +V
Sbjct: 1650 CEQCGPGYV 1658
Score = 61.3 bits (142), Expect = 6e-08
Identities = 50/175 (28%), Positives = 72/175 (41%), Gaps = 31/175 (17%)
Query: 1340 CLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYG------FPNCRPCHCP--- 1389
C C+ S+ C+ G C C+ N G C+ C+ G++G +CRPC CP
Sbjct: 764 CNCNGHASS---CDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYID 820
Query: 1390 ------STAICDDNGMC---ICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGN 1440
T D +G C G C+ C P +Q G N V +
Sbjct: 821 ASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCD 880
Query: 1441 QLQCEADSGK-CACRENVRGRVCDHCVPGHYAF----PD-CYQCTC---NRHGTT 1486
+ SG+ C C+ NV GR+C+ C G + PD C +C C +RH T+
Sbjct: 881 ERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTS 935
Score = 61.3 bits (142), Expect = 6e-08
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 16/140 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC-ECRPEFQ 386
C G++C C P Y R + L C+ C+C+ H + C E+G C +C+
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLY--LGHCELCECNGH--SDLCHPETGACSQCQHNAA 1587
Query: 387 PPDCSSCAYGYF------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C CA GY+ +C+PC C L E + L G C CE
Sbjct: 1588 GEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESL-----GAGGYRCTACE 1642
Query: 441 DGYYSPECKNCECNTVGSVS 460
GY C+ C VG+ S
Sbjct: 1643 PGYTGQYCEQCGPGYVGNPS 1662
Score = 58.0 bits (134), Expect = 6e-07
Identities = 49/175 (28%), Positives = 61/175 (34%), Gaps = 32/175 (18%)
Query: 242 PADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECT 301
P++ L + CRC G C C G+ R CE C C+ H+ C
Sbjct: 1518 PSNRPRALEVEECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLC- 1572
Query: 302 YDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
PE G C CQHN G C C P YY E CQPC
Sbjct: 1573 -HPET----------------GACSQCQHNAAGEFCELCAPGYYGDATAGTPE--DCQPC 1613
Query: 362 QC---DP-HFSTGNCEEESG---RC-ECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
C +P + + CE RC C P + C C GY P+ + C
Sbjct: 1614 ACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 56.4 bits (130), Expect = 2e-06
Identities = 51/180 (28%), Positives = 84/180 (46%), Gaps = 19/180 (10%)
Query: 3022 SFNGTDSYLRFVDVTSENPQLTL--KFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGK 3079
S +G SYL +T+ + +L L +FK P+G+L S ++ + D +SL++V G
Sbjct: 3931 SLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLF--SGGKSGPVEDFVSLAMVGGH 3988
Query: 3080 LVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDG-- 3137
L R +L +GL ++ L H SA +L D + P L G
Sbjct: 3989 LEF---RYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGS--LRVNGGRPVLRSSPGKS 4043
Query: 3138 -------VLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
+L++GGV+P +S + F GC+G+ ++NG+ L+L F S G+C
Sbjct: 4044 QGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL-GSQGIGQC 4102
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 19/141 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTA-ICD-DNGMCI-CPKNVEG 1408
+C C P IG +C C GY +C C C + +C + G C C N G
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAG 1588
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNC---NPLGVVGNQLQCEADSG-KC-ACRENVRG 1459
E C+ C P + D G C C C NP + + G +C AC G
Sbjct: 1589 EFCELCAPGYYG-DATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTG 1647
Query: 1460 RVCDHCVPGHYAFPDCYQCTC 1480
+ C+ C PG+ P C
Sbjct: 1648 QYCEQCGPGYVGNPSVQGGQC 1668
Score = 53.2 bits (122), Expect = 2e-05
Identities = 42/182 (23%), Positives = 65/182 (35%), Gaps = 21/182 (11%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C++C F P C CNC+ + C V G C+
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHA-----SSCDPV-YGHCLNCQ 784
Query: 665 DRVQGRICNDCKP-LYWNLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKS-GQCVCKQ--- 718
+G CN CK + + + C C C C + GQ C
Sbjct: 785 HNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 844
Query: 719 -HVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ-CHCHSRVEGRRC 776
+ G R+C+ C G+ C + +I + T+G+ C C + V GR C
Sbjct: 845 GYTG-RRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 903
Query: 777 DQ 778
++
Sbjct: 904 NE 905
Score = 49.2 bits (112), Expect = 3e-04
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 19/114 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH+D C P A +CQHN G C C G+ + + C+P
Sbjct: 1563 CECNGHSDLCHPETGA------CSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQP 1612
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C C +P E S GG +C C+ G C +C P Y
Sbjct: 1613 CACP------LTNP---ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGY 1657
Score = 48.0 bits (109), Expect = 6e-04
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK
Sbjct: 1247 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQ 1298
Query: 1365 VIGRTCSACRTGYYGF-----PNCRPCHC 1388
V G TCS CR ++ C PC C
Sbjct: 1299 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 47.6 bits (108), Expect = 8e-04
Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 21/106 (19%)
Query: 1341 LCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF------PNCRPCHCPST-- 1391
LC+ G ++L C+ G C C+ N G C C GYYG +C+PC CP T
Sbjct: 1562 LCECNGHSDL-CHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNP 1620
Query: 1392 -----AICDDNG----MC-ICPKNVEGENCDRCKP-YTFNFDVQRG 1426
C+ G C C G+ C++C P Y N VQ G
Sbjct: 1621 ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGG 1666
Score = 47.2 bits (107), Expect = 0.001
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 14/138 (10%)
Query: 3516 SISMEVRPRNTTGLLL-------SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSN 3568
+I +EVR +GLLL KD++ L L D +V + G+G R L +
Sbjct: 4229 TIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEAR----LVS 4284
Query: 3569 KHYLCDGNWHKIHXXXXXXXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKV 3626
+ + DG WH++ DG S G + + ++YIGG + +
Sbjct: 4285 EDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAP-DVATL 4343
Query: 3627 RGVHSRRGFTGCVRNIVV 3644
G G TGCV+N+V+
Sbjct: 4344 TGGRFSSGITGCVKNLVL 4361
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 2890 GEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD- 2948
G+G F SL +QDG + + LG+ E ++ + NDG+WH++ A R + S+ VD
Sbjct: 4254 GQGKDFISLGLQDGHLVFRYQLGSGEARLV--SEDPINDGEWHRVTALREGRRGSIQVDG 4311
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDR---GFDGCMRQISIN 2996
E++ S P+ + + ++ GG R G GC++ + ++
Sbjct: 4312 EELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4362
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 2877 FRTYAPNG-LIYLVGEGGY---FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWH 2932
F+ AP+G L++ G+ G F SL M G + + LG+ L ++ + G+WH
Sbjct: 3957 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGS--GLAVLRSAEPLALGRWH 4014
Query: 2933 KLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNF-GGNNKGILQVPDRG----FD 2987
++ A R SL V+ S+ + +L T+ + GG + P F
Sbjct: 4015 RVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFR 4074
Query: 2988 GCMRQISINGVNLDLSENL---ESIGMAY 3013
GC+ ++S+NG LDL+ + + IG Y
Sbjct: 4075 GCVGEVSVNGKRLDLTYSFLGSQGIGQCY 4103
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 3361 FLAFFMRDAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVD-SEMVGET 3419
F++ ++D L + + G + S ND +WH VT R G G + VD E+V
Sbjct: 4259 FISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGR 4318
Query: 3420 SVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMN 3466
S N ++ Y GG V + F GC+K L+++
Sbjct: 4319 SPGPNVAVNAKGSVYIGGAPDV---ATLTGGRFSSGITGCVKNLVLH 4362
Score = 43.2 bits (97), Expect = 0.018
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 8/95 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQC-VC 716
E C+C G C DC P Y G CE C CN L C+ ++G C C
Sbjct: 1528 EECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL-----CHPETGACSQC 1582
Query: 717 KQHVGERQCDQCLDGFYRLQT-NDVFGCTECDCDI 750
+ + C+ C G+Y T C C C +
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPL 1617
Score = 42.7 bits (96), Expect = 0.024
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 15/72 (20%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKDG-------CDHCNCNTGYSVGFMCN-ATGQC-EC 2044
+CRC G G C CA G YT+ G C+ C CN G+S +C+ TG C +C
Sbjct: 1529 ECRCPPGYIGLSCQDCAPG---YTRTGSGLYLGHCELCECN-GHS--DLCHPETGACSQC 1582
Query: 2045 LPGVIGEKCDRC 2056
GE C+ C
Sbjct: 1583 QHNAAGEFCELC 1594
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 16/195 (8%)
Query: 3478 NALRCVDNIEDGVYFEA-SNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGK 3536
+ LRC E+GV S + +YL L E+ + +E +P G+LL GK
Sbjct: 3917 SGLRC----EEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGK 3972
Query: 3537 ----KDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXX 3592
+D++ L ++ + E G+G L + L G WH++
Sbjct: 3973 SGPVEDFVSLAMVGGHLEFRYELGSG----LAVLRSAEPLALGRWHRVSAERLNKDGSLR 4028
Query: 3593 XDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVK 3650
+G + G + H+ LY+GG E + + F GCV + V +
Sbjct: 4029 VNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLD 4088
Query: 3651 VPNSAVGRGAHVGVC 3665
+ S +G +G C
Sbjct: 4089 LTYSFLG-SQGIGQC 4102
Score = 39.1 bits (87), Expect = 0.30
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 21/147 (14%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT G +L+ G G + D++ +G+Q+G+ +G AR+ +
Sbjct: 4235 RTSTASGLLLWQGVEVG---EAGQGKDFISLGLQDGHLVFRYQLGSGE------ARLVSE 4285
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
+ D W++V R GRR + + +G + + + PG + N K +Y+
Sbjct: 4286 DPINDGEWHRVTALREGRRGSIQV-----DGEELVSGRS---PGPNVAVN---AKGSVYI 4334
Query: 2790 GGVPSDAKLQGISFPA-FEGQIEELMI 2815
GG P A L G F + G ++ L++
Sbjct: 4335 GGAPDVATLTGGRFSSGITGCVKNLVL 4361
Score = 38.7 bits (86), Expect = 0.39
Identities = 30/134 (22%), Positives = 45/134 (33%), Gaps = 18/134 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C C + + CE C C+ + G QC+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN------GHSDLCHPETGACSQCQ 1583
Query: 665 DRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKSG---QC-VCKQ 718
G C C P Y+ + P C+ C C L N C + +C C+
Sbjct: 1584 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1643
Query: 719 HVGERQCDQCLDGF 732
+ C+QC G+
Sbjct: 1644 GYTGQYCEQCGPGY 1657
Score = 37.5 bits (83), Expect = 0.90
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 1932 CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
C G D +S++ CVC G G +C+ + L C P CG + D
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEH--------SQALHCHPEACGPDATCVNRPD 3904
Query: 1991 DNG-QCRCAKGVTGKQCDQ 2008
G CRC G +G +C++
Sbjct: 3905 GRGYTCRCHLGRSGLRCEE 3923
Score = 37.1 bits (82), Expect = 1.2
Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 9/118 (7%)
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQCRCAKGVTGKQCDQCAA 2011
V G D P+ G + L C+C C D D G R G+ C++C+
Sbjct: 1102 VSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSC 1161
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATG-QCE-CLPGVIGEKCDRCPERWVLIPQEG 2067
+ C TG G + G +CE C PG G+ P+ L P G
Sbjct: 1162 ------HGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG 1213
Score = 37.1 bits (82), Expect = 1.2
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 13/83 (15%)
Query: 1737 QCPRAYRGLSCEQCAEGHYR-LPSGF---CVPCQC------NGHSDQCD-VNTG--ICLN 1783
QC G CE CA G+Y +G C PC C N S C+ + G C
Sbjct: 1581 QCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTA 1640
Query: 1784 CADNTIGDHCEFCMSGYHGDATV 1806
C G +CE C GY G+ +V
Sbjct: 1641 CEPGYTGQYCEQCGPGYVGNPSV 1663
Score = 36.3 bits (80), Expect = 2.1
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 12/94 (12%)
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCV 546
G + PTC+ C G + + S C+C AGF G RC+ + Q L C
Sbjct: 3841 GISHCPTCRDRPCQNGG-QCHDSESSSYVCVCPAGFTGSRCE------HSQAL----HCH 3889
Query: 547 PCNCDPTGSTSTSCSADG-KCNCLTNFGGAQCDQ 579
P C P + G C C G +C++
Sbjct: 3890 PEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEE 3923
Score = 34.7 bits (76), Expect = 6.4
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 15/130 (11%)
Query: 1269 TSKGVWLDYVLVIEASDFTDAVLTEANILDYTR-----EFIEQCASYNYYISPNETGL-C 1322
T G++L + + E + +D E + EF E CA Y + T C
Sbjct: 1551 TGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDC 1610
Query: 1323 REAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPN 1382
+ +T+ N +R C + +G+ C C+P G+ C C GY G P+
Sbjct: 1611 QPCACPLTNPENMFSRTC--ESLGAGGYRCTA------CEPGYTGQYCEQCGPGYVGNPS 1662
Query: 1383 CRPCHC-PST 1391
+ C P T
Sbjct: 1663 VQGGQCLPET 1672
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 320 bits (785), Expect = 8e-86
Identities = 197/549 (35%), Positives = 255/549 (46%), Gaps = 55/549 (10%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPS-TAICD-DNGMCI-CPKNVEG 1408
QC C P G +C C TGY P+ C C C + C+ + G C C + EG
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQLQ-CEADSG---KC-ACRENVRG 1459
C++C+P + D QRG C C C G C D+ C AC G
Sbjct: 1185 PRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSG 1243
Query: 1460 RVCDHCVPGHYAFPD----CYQ---------CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
R C+ C PG+Y P C + C C+ G+ CD QC CK V G
Sbjct: 1244 RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGL 1302
Query: 1507 ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVD----VLIN 1562
C C+ +F+L NPDGC CFC G T +C+SS YT I + P D L+N
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLIS--THFAPGDFQGFALVN 1360
Query: 1563 --NTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTV 1620
L V + L+ G N + Y+ PE Y G ++ +YGG L YT+
Sbjct: 1361 PQRNSRLTGEFTVEPVPEGAQLSFG-NFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTL 1419
Query: 1621 HYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMP--WTHSVKLSEEEFSTLDGAPV 1678
YT G ++ PDV I G N LV QP + P ++ + EE + DG P
Sbjct: 1420 SYTAGPQGSPLSDPDVQITGNNIMLV---ASQPALQGPERRSYEIMFREEFWRRPDGQPA 1476
Query: 1679 TRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQC 1738
TR+ + AL ++ L IRA++ + S+S V LE+ RA VEEC+C
Sbjct: 1477 TREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRP----RALEVEECRC 1532
Query: 1739 PRAYRGLSCEQCAEGHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
P Y GLSC+ CA G+ R SG C C+CNGHSD C TG C C N G+ CE
Sbjct: 1533 PPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCE 1592
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
C GY+GDAT GTP DC CACP+ P N F+ +C+ G C+PGY G CE
Sbjct: 1593 LCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQ 1652
Query: 1855 CAAGYYGIP 1863
C GY G P
Sbjct: 1653 CGPGYVGNP 1661
Score = 302 bits (741), Expect = 2e-80
Identities = 194/607 (31%), Positives = 268/607 (44%), Gaps = 41/607 (6%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPSTAI-CDD-NGMCI-CPKNVEG 1408
+C C G +C +C + P C C+C A CD G C+ C N EG
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEG 789
Query: 1409 ENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ----CEADS---GKC-ACRENVRGR 1460
C++CK F ++ C P + + C D+ C AC GR
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 849
Query: 1461 VCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ------CYCKTNVRGQACDTCKEE 1514
C+ C PG+ P C CD+ + C CK NV G+ C+ C +
Sbjct: 850 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Query: 1515 YFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVP 1574
F+L NPDGC KCFC G + C+SS ++ A + + P + N H
Sbjct: 910 SFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASE-EPGHFSLTNAAS--THTTNE 966
Query: 1575 ELTNVTVLTVGLNDGVTNGKVAYF-GAPEYYLGKRLTSYGGYLTYTVHYTTR-GDGDAVA 1632
+ + T +G + YF P +LG ++TSYGG L +TV ++ G
Sbjct: 967 GIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHG 1026
Query: 1633 APDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISG 1692
P V++ G N L H+ ++P G P T V E+ + DG P TR+ + AL I
Sbjct: 1027 QPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDT 1086
Query: 1693 LYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAE 1752
L IRASY + E+ +S + +++ V G + A VE+C CP YRG SC+ C
Sbjct: 1087 LLIRASYAQQPAESRVSGISMDVAVPEETGQD----PALEVEQCSCPPGYRGPSCQDCDT 1142
Query: 1753 GHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGT 1808
G+ R PSG C C C+GHS+ C+ TG C C +T G CE C GY+GDA GT
Sbjct: 1143 GYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGT 1202
Query: 1809 PRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDL 1868
P+DC +C C + A +C L +G C PG+ G CE CA GYYG P
Sbjct: 1203 PQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQP 1262
Query: 1869 HTGDYCKPCNCSGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCAP-GFYGDAIFSK 1925
D P N +PQ S CD+ G C +C G C+ C P F+ A
Sbjct: 1263 CQRDSQVPGPIGCNCDPQGSVSSQCDAA-GQC-QCKAQVEGLTCSHCRPHHFHLSASNPD 1320
Query: 1926 NCTACIC 1932
C C C
Sbjct: 1321 GCLPCFC 1327
Score = 217 bits (529), Expect = 8e-55
Identities = 141/434 (32%), Positives = 194/434 (44%), Gaps = 24/434 (5%)
Query: 1511 CKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI----DEMVDWYPVDVLINNTIE 1566
C + +F L+ + C CFCFG T+ C S+ I D+ D+ V+V +
Sbjct: 505 CPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPG 562
Query: 1567 LYPHEDVPELTNVTVLTVGLNDGVTNGKV--AYFGAPEYYLGKRLTSYGGYLTYTVHYT- 1623
P + ++ L D V +++ PE +LG ++ SYGG L Y V Y
Sbjct: 563 TPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYEL 622
Query: 1624 TRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQF 1683
RG + V PDV++ G L+ G V+ SEE + G PV R +
Sbjct: 623 ARGMLEPVQRPDVVLMGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPVQRAEL 682
Query: 1684 MHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYR 1743
+ L ++ + I+ Y LS++ ++ V + RA SVEEC+CP Y
Sbjct: 683 LQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHG----RAHSVEECRCPIGYS 738
Query: 1744 GLSCEQCAEGHYRLPSG----FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSG 1799
GLSCE C R+P G C C CNGH+ CD G CLNC NT G C C +G
Sbjct: 739 GLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAG 798
Query: 1800 YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGY 1859
+ GDA T C C CP S F+ +C L +G C PGY G RCE CA GY
Sbjct: 799 FFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY 858
Query: 1860 YGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG-FY 1918
G P + G C+P N + + GS + +G+ +C NN G CN CA G F+
Sbjct: 859 EGNP----IQPGGKCRPVN-QEIVRCDERGSMGT-SGEACRCKNNVVGRLCNECADGSFH 912
Query: 1919 GDAIFSKNCTACIC 1932
C C C
Sbjct: 913 LSTRNPDGCLKCFC 926
Score = 120 bits (288), Expect = 1e-25
Identities = 72/208 (34%), Positives = 95/208 (45%), Gaps = 26/208 (12%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S+ C C GY G CE C A + +P L T C CNC+G+ + SCD + G
Sbjct: 727 SVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGT---CSGCNCNGHAS-----SCDPVYG 778
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTT--------GT 1946
CL C +NT G CN C GF+GDA+ + +C C C + S T T
Sbjct: 779 HCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 838
Query: 1947 C-VCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIA--SESTQCDDDNGQCRCAKGV 2001
C C PG G +C+ CAP + G + G C P N I E CRC V
Sbjct: 839 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNV 898
Query: 2002 TGKQCDQCAAGFWNYT---KDGCDHCNC 2026
G+ C++CA G ++ + DGC C C
Sbjct: 899 VGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 111 bits (268), Expect = 3e-23
Identities = 67/202 (33%), Positives = 88/202 (43%), Gaps = 32/202 (15%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C+C Y G +C C GY P TC+ C+C C+ +G C C+
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHS---EACEPETGACQGCQHHT 1182
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNC--DPT-GSTSTSC--SADGK--CN-CLTNFG 573
GPRC+QC GYY G + C C C DP G + +C DG C+ C
Sbjct: 1183 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 574 GAQCDQCSPGYYKYPD----C---------LSCNCDVSGSIGSTCDDNGLCHCKSNFDGA 620
G C++C+PGYY P C + CNCD GS+ S CD G C CK+ +G
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 1302
Query: 621 KCDTCREQFYNYPACEECNCDP 642
C CR ++ A C P
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLP 1324
Score = 102 bits (245), Expect = 2e-20
Identities = 72/226 (31%), Positives = 103/226 (45%), Gaps = 41/226 (18%)
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTST 558
+ +G +P++ +V QC C G+ GP C C +GY G C C+C S
Sbjct: 1113 EETGQDPAL--EVE-QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSE 1166
Query: 559 SCSAD-GKCN-CLTNFGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC-- 605
+C + G C C + G +C+QC PGYY DC C C +G TC
Sbjct: 1167 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFL 1226
Query: 606 --DDNGLCH-CKSNFDGAKCDTCREQFYNYPA----CEE---------CNCDPRGVTASF 649
D + C C G C+ C +Y P+ C+ CNCDP+G +S
Sbjct: 1227 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS- 1285
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C + AG+ CQCK +V+G C+ C+P +++L NP GC C C
Sbjct: 1286 -QCDA--AGQ-CQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 101 bits (242), Expect = 5e-20
Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 38/210 (18%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLCP-C 427
E +C C P ++ P C C GY P+ C+ C+C+ E C P G C C
Sbjct: 1122 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGC 1178
Query: 428 KYNYAGKSCEICEDGYYS-------PECKNCEC---NTVGSVSYVCDKLT-GDCTCKS-- 474
+++ G CE C+ GYY +C+ C C G ++ C T G TC +
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 475 -KYSGRTCNQCQAGYYNYPT----CK---------PCNCDTSGTEPSICDDVSGQCICKA 520
+SGR C +C GYY P+ C+ CNCD G+ S C D +GQC CKA
Sbjct: 1239 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAAGQCQCKA 1297
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
G C C ++ C+PC C
Sbjct: 1298 QVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 94.7 bits (225), Expect = 6e-18
Identities = 62/202 (30%), Positives = 88/202 (43%), Gaps = 26/202 (12%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKC-NCLTN 571
+C C G+ G C+ C ++ +V G C CNC+ G S+ G C NC N
Sbjct: 730 ECRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCNCN--GHASSCDPVYGHCLNCQHN 786
Query: 572 FGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC----DDNGLCH-CKSNF 617
G QC++C G++ C C C D S TC D C C +
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 618 DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC---GSV-PAGELCQCKDRVQGRICN 673
G +C++C + P C P V C GS+ +GE C+CK+ V GR+CN
Sbjct: 847 TGRRCESCAPGYEGNPIQPGGKCRP--VNQEIVRCDERGSMGTSGEACRCKNNVVGRLCN 904
Query: 674 DCKPLYWNLQEYNPFGCEQCNC 695
+C ++L NP GC +C C
Sbjct: 905 ECADGSFHLSTRNPDGCLKCFC 926
Score = 87.0 bits (206), Expect = 1e-15
Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C PGY G C+ CA GY + L+ G +C+ C C+G+ + C G C +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGY--TRTGSGLYLG-HCELCECNGHSD-----LCHPETGACSQ 1581
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFS--KNCTACIC-----DEFGMADCDSTTG---TC-VC 1949
C +N AG C LCAPG+YGDA ++C C C + C+S C C
Sbjct: 1582 CQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTAC 1641
Query: 1950 RPGVIGEKCDRCAPDHWG 1967
PG G+ C++C P + G
Sbjct: 1642 EPGYTGQYCEQCGPGYVG 1659
Score = 86.2 bits (204), Expect = 2e-15
Identities = 65/222 (29%), Positives = 93/222 (41%), Gaps = 38/222 (17%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCE-CRPEF 385
+C G +C C Y R + L C+ C C H CE E+G C+ C+
Sbjct: 1127 SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGHSEA--CEPETGACQGCQHHT 1182
Query: 386 QPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE--H-C-TPTDG--LCP-CKYNYA 432
+ P C C GY+ +C+ C C + G+ H C TDG C C ++
Sbjct: 1183 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 433 GKSCEICEDGYY-SPE----CKN---------CECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G+ CE C GYY +P C+ C C+ GSVS CD G C CK++ G
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEG 1301
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
TC+ C+ +++ P C P C ++ QC A
Sbjct: 1302 LTCSHCRPHHFHLSASNPDGC-----LPCFCMGITQQCASSA 1338
Score = 85.0 bits (201), Expect = 5e-15
Identities = 60/215 (27%), Positives = 91/215 (42%), Gaps = 29/215 (13%)
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDS 1942
P++ G ++ + C G +C C G+ ++ C C C A C+
Sbjct: 1112 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA-CEP 1170
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC------GIASESTQCDDD- 1991
TG C C+ G +C++C P ++G T C C C G A+ + D D
Sbjct: 1171 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDG 1230
Query: 1992 NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---------CNCNTGYSVGFMCNAT 2039
+ C C+ G +G+ C++CA G++ G C CNC+ SV C+A
Sbjct: 1231 HPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA 1290
Query: 2040 GQCECLPGVIGEKCDRC-PERWVLIPQ--EGCLEC 2071
GQC+C V G C C P + L +GCL C
Sbjct: 1291 GQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 1325
Score = 84.6 bits (200), Expect = 6e-15
Identities = 68/235 (28%), Positives = 91/235 (38%), Gaps = 42/235 (17%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC G C C + F R+ +C CNC+ H + C DP
Sbjct: 731 CRCPIGYSGLSCESCDAHFT----RVPGGPYLGTCSGCNCNGHASSC--DPVY------- 777
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC-----DPHFS 368
G CLNCQHNTEG CNKC+ ++ K C+PC C FS
Sbjct: 778 ---------GHCLNCQHNTEGPQCNKCKAGFFGDAMKA--TATSCRPCPCPYIDASRRFS 826
Query: 369 TGNCEEESGR--CE-CRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHCTP 420
+ G+ C+ C P + C SCA GY P C+P + +
Sbjct: 827 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMG 886
Query: 421 TDG-LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKS 474
T G C CK N G+ C C DG + +N + G + C ++ CT S
Sbjct: 887 TSGEACRCKNNVVGRLCNECADGSFHLSTRNPD----GCLKCFCMGVSRHCTSSS 937
Score = 83.0 bits (196), Expect = 2e-14
Identities = 58/205 (28%), Positives = 86/205 (41%), Gaps = 26/205 (12%)
Query: 316 NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE 375
+GR +C C G++C C + R G + L C C C+ H S+ C+
Sbjct: 722 HGRAHSVEEC-RCPIGYSGLSCESCDAHFTRVPGGPY--LGTCSGCNCNGHASS--CDPV 776
Query: 376 SGRC-ECRPEFQPPDCSSCAYGYFD------YPNCKPCTC---NLNGTEGEHC-TPTDGL 424
G C C+ + P C+ C G+F +C+PC C + + + C TDG
Sbjct: 777 YGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQ 836
Query: 425 CPCKY---NYAGKSCEICEDGYY-SPECKNCECNTVGSVSYVCDK-----LTGD-CTCKS 474
C Y G+ CE C GY +P +C V CD+ +G+ C CK+
Sbjct: 837 ATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKN 896
Query: 475 KYSGRTCNQCQAGYYNYPTCKPCNC 499
GR CN+C G ++ T P C
Sbjct: 897 NVVGRLCNECADGSFHLSTRNPDGC 921
Score = 81.8 bits (193), Expect = 4e-14
Identities = 56/202 (27%), Positives = 83/202 (41%), Gaps = 23/202 (11%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD------CLSCNCDVSGSIGSTCDD-NGLC-HCKSN 616
+C C + G C+ C + + P C CNC+ S+CD G C +C+ N
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCN---GHASSCDPVYGHCLNCQHN 786
Query: 617 FDGAKCDTCREQFYN------YPACEECNCDPRGVTASFAG-CGSVPAGEL-CQ-CKDRV 667
+G +C+ C+ F+ +C C C + F+ C G+ C C
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 668 QGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
GR C C P Y P G C N + + G+ T C CK +V R C+
Sbjct: 847 TGRRCESCAPGYEG-NPIQPGGKCRPVNQEIV-RCDERGSMGTSGEACRCKNNVVGRLCN 904
Query: 727 QCLDGFYRLQTNDVFGCTECDC 748
+C DG + L T + GC +C C
Sbjct: 905 ECADGSFHLSTRNPDGCLKCFC 926
Score = 78.2 bits (184), Expect = 5e-13
Identities = 69/248 (27%), Positives = 94/248 (37%), Gaps = 52/248 (20%)
Query: 244 DPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYD 303
DPA L + C C GP C C +G+ R +CE C+CH H+ C +
Sbjct: 1118 DPA--LEVEQCSCPPGYRGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--E 1169
Query: 304 PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC 363
PE G C CQH+TEG C +C+P YY +R D CQ C C
Sbjct: 1170 PET----------------GACQGCQHHTEGPRCEQCQPGYYGD-AQRGTPQD-CQLCPC 1211
Query: 364 --DPHF--STGNC---EEESGRCE-CRPEFQPPDCSSCAYGYFDYPN----CK------- 404
DP + C + C+ C P C CA GY+ P+ C+
Sbjct: 1212 YGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 1271
Query: 405 --PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
C C+ G+ C G C CK G +C C ++ N + G +
Sbjct: 1272 PIGCNCDPQGSVSSQCDAA-GQCQCKAQVEGLTCSHCRPHHFHLSASNPD----GCLPCF 1326
Query: 463 CDKLTGDC 470
C +T C
Sbjct: 1327 CMGITQQC 1334
Score = 77.4 bits (182), Expect = 9e-13
Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 1158 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 1206
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + + ++ +G C C G +C +C P YY P
Sbjct: 1207 QLCPCYG-------DPAAGQAAHTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNP 1257
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----- 398
+ + D P C CDP S + + +G+C+C+ + + CS C +F
Sbjct: 1258 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSAS 1317
Query: 399 DYPNCKPCTC 408
+ C PC C
Sbjct: 1318 NPDGCLPCFC 1327
Score = 74.9 bits (176), Expect = 5e-12
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPDCL---SCN-CDVSGSIGSTCDDNGLCH-CKSNFDG 619
+C+C + G C C GY + P L +C C G + + G C C+ + +G
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 620 AKCDTCREQFYNYPA------CEECNC--DPRGVTASFAGCGSVPAGELCQ-CKDRVQGR 670
+C+ C+ +Y C+ C C DP A+ C C GR
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1244
Query: 671 ICNDCKPLYW-NLQEYNPF-------GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C C P Y+ N + P G CNC+ G+++S C+ +GQC CK V
Sbjct: 1245 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS--QCDA-AGQCQCKAQVEG 1301
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDC 748
C C + L ++ GC C C
Sbjct: 1302 LTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 73.7 bits (173), Expect = 1e-11
Identities = 48/146 (32%), Positives = 64/146 (43%), Gaps = 24/146 (16%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGY------FDYPNCKPCTCNLNGTEGEHCTPTDGLCP-C 427
E C C P + C CA GY +C+ C CN + C P G C C
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQC 1582
Query: 428 KYNYAGKSCEICEDGYY------SPE-CKNCEC---NTVGSVSYVCDKLTGD---CT-CK 473
++N AG+ CE+C GYY +PE C+ C C N S C+ L CT C+
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACE 1642
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNC 499
Y+G+ C QC GY P+ + C
Sbjct: 1643 PGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/196 (27%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQ-C 663
C C + G C C + P+ CE C+C P CQ C
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE-------PETGACQGC 1178
Query: 664 KDRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCN---LAGTLNSLGACNTKSGQ-C-VCK 717
+ +G C C+P Y+ + Q P C+ C C AG +T C C
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 718 QHVGERQCDQCLDGFYR--------LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHS 769
R C++C G+Y + + V G C+CD GS+ + CD GQC C +
Sbjct: 1239 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKA 1297
Query: 770 RVEGRRCDQPIRAHYF 785
+VEG C R H+F
Sbjct: 1298 QVEGLTCSH-CRPHHF 1312
Score = 70.5 bits (165), Expect = 1e-10
Identities = 62/197 (31%), Positives = 74/197 (37%), Gaps = 34/197 (17%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGHA +C+P G+ CQHNT GPQCNKC +GF + + SC P
Sbjct: 764 CNCNGHASSCDPV--YGHC----LNCQHNTEGPQCNKCKAGFFGDAMKATAT----SCRP 813
Query: 291 CNCHNHTTECTYDPEID-EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C P ID +R S +G C C G C C P Y G
Sbjct: 814 CPC----------PYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY---EG 860
Query: 350 KRWDELDVCQP-----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
C+P +CD S G E C C+ C+ CA G F
Sbjct: 861 NPIQPGGKCRPVNQEIVRCDERGSMGTSGE---ACRCKNNVVGRLCNECADGSFHLSTRN 917
Query: 405 PCTCNLNGTEG--EHCT 419
P C G HCT
Sbjct: 918 PDGCLKCFCMGVSRHCT 934
Score = 70.5 bits (165), Expect = 1e-10
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 24/144 (16%)
Query: 425 CPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDCT-CKSKY 476
C C Y G SC+ C GY Y C+ CECN S +C TG C+ C+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQCQHNA 1586
Query: 477 SGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSI---CDDVSG---QCI-CKAGFG 523
+G C C GYY T C+PC C + E C+ + +C C+ G+
Sbjct: 1587 AGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYT 1646
Query: 524 GPRCDQCLSGYYMQVLGRERQCVP 547
G C+QC GY + QC+P
Sbjct: 1647 GQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 68.5 bits (160), Expect = 4e-10
Identities = 55/208 (26%), Positives = 75/208 (36%), Gaps = 26/208 (12%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPN---CKPCT-CNLNGTEGEHCTPTDGLC-PCKYNYAG 433
C C + C SC + P C+ CN NG C P G C C++N G
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNG-HASSCDPVYGHCLNCQHNTEG 789
Query: 434 KSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKL----TGDCTCKS---KYSGR 479
C C+ G++ + C+ C C + + D G TC + Y+GR
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 849
Query: 480 TCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD-----VSGQ-CICKAGFGGPRCDQCLSG 533
C C GY P C E CD+ SG+ C CK G C++C G
Sbjct: 850 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Query: 534 YYMQVLGRERQCVPCNCDPTGSTSTSCS 561
+ C+ C C TS S
Sbjct: 910 SFHLSTRNPDGCLKCFCMGVSRHCTSSS 937
Score = 66.9 bits (156), Expect = 1e-09
Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 19/143 (13%)
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
+C C Y G +C C GY + C+ C C+ +C +G C C+
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHS---DLCHPETGACSQCQHN 1585
Query: 522 FGGPRCDQCLSGYYMQVL-GRERQCVPCNC---DPTGSTSTSCSADG----KCN-CLTNF 572
G C+ C GYY G C PC C +P S +C + G +C C +
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 573 GGAQCDQCSPGYYKYPDCLSCNC 595
G C+QC PGY P C
Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 64.9 bits (151), Expect = 5e-09
Identities = 53/197 (26%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 1900 KCVNNTAGAACNLCAPGF--YGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGE 1956
+C +G +C C F + C+ C C+ + CD G C+ C+ G
Sbjct: 732 RCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHA-SSCDPVYGHCLNCQHNTEGP 790
Query: 1957 KCDRCAPDHWG---LNTGLGCTPCNCGIASESTQCDDD-----NGQCRC---AKGVTGKQ 2005
+C++C +G T C PC C S + D +GQ C A G TG++
Sbjct: 791 QCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRR 850
Query: 2006 CDQCAAGF-WNYTKDG--CDHCN-----CNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
C+ CA G+ N + G C N C+ S+G A C C V+G C+ C
Sbjct: 851 CESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEA---CRCKNNVVGRLCNECA 907
Query: 2058 ERWVLIP---QEGCLEC 2071
+ + +GCL+C
Sbjct: 908 DGSFHLSTRNPDGCLKC 924
Score = 62.9 bits (146), Expect = 2e-08
Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN-CGIASESTQCDDDNGQC-RCAKGVTGK 2004
C C PG IG C CAP + +GL C C S C + G C +C G+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGE 1589
Query: 2005 QCDQCAAGFWN----YTKDGCDHCNC---NTGYSVGFMCNATG----QC-ECLPGVIGEK 2052
C+ CA G++ T + C C C N C + G +C C PG G+
Sbjct: 1590 FCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQY 1649
Query: 2053 CDRCPERWV 2061
C++C +V
Sbjct: 1650 CEQCGPGYV 1658
Score = 61.3 bits (142), Expect = 6e-08
Identities = 50/175 (28%), Positives = 72/175 (41%), Gaps = 31/175 (17%)
Query: 1340 CLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYG------FPNCRPCHCP--- 1389
C C+ S+ C+ G C C+ N G C+ C+ G++G +CRPC CP
Sbjct: 764 CNCNGHASS---CDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYID 820
Query: 1390 ------STAICDDNGMC---ICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGN 1440
T D +G C G C+ C P +Q G N V +
Sbjct: 821 ASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCD 880
Query: 1441 QLQCEADSGK-CACRENVRGRVCDHCVPGHYAF----PD-CYQCTC---NRHGTT 1486
+ SG+ C C+ NV GR+C+ C G + PD C +C C +RH T+
Sbjct: 881 ERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTS 935
Score = 61.3 bits (142), Expect = 6e-08
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 16/140 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC-ECRPEFQ 386
C G++C C P Y R + L C+ C+C+ H + C E+G C +C+
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLY--LGHCELCECNGH--SDLCHPETGACSQCQHNAA 1587
Query: 387 PPDCSSCAYGYF------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C CA GY+ +C+PC C L E + L G C CE
Sbjct: 1588 GEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESL-----GAGGYRCTACE 1642
Query: 441 DGYYSPECKNCECNTVGSVS 460
GY C+ C VG+ S
Sbjct: 1643 PGYTGQYCEQCGPGYVGNPS 1662
Score = 58.0 bits (134), Expect = 6e-07
Identities = 49/175 (28%), Positives = 61/175 (34%), Gaps = 32/175 (18%)
Query: 242 PADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECT 301
P++ L + CRC G C C G+ R CE C C+ H+ C
Sbjct: 1518 PSNRPRALEVEECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLC- 1572
Query: 302 YDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
PE G C CQHN G C C P YY E CQPC
Sbjct: 1573 -HPET----------------GACSQCQHNAAGEFCELCAPGYYGDATAGTPE--DCQPC 1613
Query: 362 QC---DP-HFSTGNCEEESG---RC-ECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
C +P + + CE RC C P + C C GY P+ + C
Sbjct: 1614 ACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 56.4 bits (130), Expect = 2e-06
Identities = 51/180 (28%), Positives = 84/180 (46%), Gaps = 19/180 (10%)
Query: 3022 SFNGTDSYLRFVDVTSENPQLTL--KFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGK 3079
S +G SYL +T+ + +L L +FK P+G+L S ++ + D +SL++V G
Sbjct: 3931 SLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLF--SGGKSGPVEDFVSLAMVGGH 3988
Query: 3080 LVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDG-- 3137
L R +L +GL ++ L H SA +L D + P L G
Sbjct: 3989 LEF---RYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGS--LRVNGGRPVLRSSPGKS 4043
Query: 3138 -------VLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
+L++GGV+P +S + F GC+G+ ++NG+ L+L F S G+C
Sbjct: 4044 QGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL-GSQGIGQC 4102
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 19/141 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTA-ICD-DNGMCI-CPKNVEG 1408
+C C P IG +C C GY +C C C + +C + G C C N G
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAG 1588
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNC---NPLGVVGNQLQCEADSG-KC-ACRENVRG 1459
E C+ C P + D G C C C NP + + G +C AC G
Sbjct: 1589 EFCELCAPGYYG-DATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTG 1647
Query: 1460 RVCDHCVPGHYAFPDCYQCTC 1480
+ C+ C PG+ P C
Sbjct: 1648 QYCEQCGPGYVGNPSVQGGQC 1668
Score = 53.2 bits (122), Expect = 2e-05
Identities = 42/182 (23%), Positives = 65/182 (35%), Gaps = 21/182 (11%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C++C F P C CNC+ + C V G C+
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHA-----SSCDPV-YGHCLNCQ 784
Query: 665 DRVQGRICNDCKP-LYWNLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKS-GQCVCKQ--- 718
+G CN CK + + + C C C C + GQ C
Sbjct: 785 HNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 844
Query: 719 -HVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ-CHCHSRVEGRRC 776
+ G R+C+ C G+ C + +I + T+G+ C C + V GR C
Sbjct: 845 GYTG-RRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 903
Query: 777 DQ 778
++
Sbjct: 904 NE 905
Score = 49.2 bits (112), Expect = 3e-04
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 19/114 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH+D C P A +CQHN G C C G+ + + C+P
Sbjct: 1563 CECNGHSDLCHPETGA------CSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQP 1612
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C C +P E S GG +C C+ G C +C P Y
Sbjct: 1613 CACP------LTNP---ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGY 1657
Score = 48.0 bits (109), Expect = 6e-04
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK
Sbjct: 1247 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQ 1298
Query: 1365 VIGRTCSACRTGYYGF-----PNCRPCHC 1388
V G TCS CR ++ C PC C
Sbjct: 1299 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 47.6 bits (108), Expect = 8e-04
Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 21/106 (19%)
Query: 1341 LCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF------PNCRPCHCPST-- 1391
LC+ G ++L C+ G C C+ N G C C GYYG +C+PC CP T
Sbjct: 1562 LCECNGHSDL-CHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNP 1620
Query: 1392 -----AICDDNG----MC-ICPKNVEGENCDRCKP-YTFNFDVQRG 1426
C+ G C C G+ C++C P Y N VQ G
Sbjct: 1621 ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGG 1666
Score = 47.2 bits (107), Expect = 0.001
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 14/138 (10%)
Query: 3516 SISMEVRPRNTTGLLL-------SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSN 3568
+I +EVR +GLLL KD++ L L D +V + G+G R L +
Sbjct: 4229 TIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEAR----LVS 4284
Query: 3569 KHYLCDGNWHKIHXXXXXXXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKV 3626
+ + DG WH++ DG S G + + ++YIGG + +
Sbjct: 4285 EDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAP-DVATL 4343
Query: 3627 RGVHSRRGFTGCVRNIVV 3644
G G TGCV+N+V+
Sbjct: 4344 TGGRFSSGITGCVKNLVL 4361
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 2890 GEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD- 2948
G+G F SL +QDG + + LG+ E ++ + NDG+WH++ A R + S+ VD
Sbjct: 4254 GQGKDFISLGLQDGHLVFRYQLGSGEARLV--SEDPINDGEWHRVTALREGRRGSIQVDG 4311
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDR---GFDGCMRQISIN 2996
E++ S P+ + + ++ GG R G GC++ + ++
Sbjct: 4312 EELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4362
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 2877 FRTYAPNG-LIYLVGEGGY---FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWH 2932
F+ AP+G L++ G+ G F SL M G + + LG+ L ++ + G+WH
Sbjct: 3957 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGS--GLAVLRSAEPLALGRWH 4014
Query: 2933 KLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNF-GGNNKGILQVPDRG----FD 2987
++ A R SL V+ S+ + +L T+ + GG + P F
Sbjct: 4015 RVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFR 4074
Query: 2988 GCMRQISINGVNLDLSENL---ESIGMAY 3013
GC+ ++S+NG LDL+ + + IG Y
Sbjct: 4075 GCVGEVSVNGKRLDLTYSFLGSQGIGQCY 4103
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 3361 FLAFFMRDAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVD-SEMVGET 3419
F++ ++D L + + G + S ND +WH VT R G G + VD E+V
Sbjct: 4259 FISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGR 4318
Query: 3420 SVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMN 3466
S N ++ Y GG V + F GC+K L+++
Sbjct: 4319 SPGPNVAVNAKGSVYIGGAPDV---ATLTGGRFSSGITGCVKNLVLH 4362
Score = 43.2 bits (97), Expect = 0.018
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 8/95 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQC-VC 716
E C+C G C DC P Y G CE C CN L C+ ++G C C
Sbjct: 1528 EECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL-----CHPETGACSQC 1582
Query: 717 KQHVGERQCDQCLDGFYRLQT-NDVFGCTECDCDI 750
+ + C+ C G+Y T C C C +
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPL 1617
Score = 42.7 bits (96), Expect = 0.024
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 15/72 (20%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKDG-------CDHCNCNTGYSVGFMCN-ATGQC-EC 2044
+CRC G G C CA G YT+ G C+ C CN G+S +C+ TG C +C
Sbjct: 1529 ECRCPPGYIGLSCQDCAPG---YTRTGSGLYLGHCELCECN-GHS--DLCHPETGACSQC 1582
Query: 2045 LPGVIGEKCDRC 2056
GE C+ C
Sbjct: 1583 QHNAAGEFCELC 1594
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 16/195 (8%)
Query: 3478 NALRCVDNIEDGVYFEA-SNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGK 3536
+ LRC E+GV S + +YL L E+ + +E +P G+LL GK
Sbjct: 3917 SGLRC----EEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGK 3972
Query: 3537 ----KDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXX 3592
+D++ L ++ + E G+G L + L G WH++
Sbjct: 3973 SGPVEDFVSLAMVGGHLEFRYELGSG----LAVLRSAEPLALGRWHRVSAERLNKDGSLR 4028
Query: 3593 XDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVK 3650
+G + G + H+ LY+GG E + + F GCV + V +
Sbjct: 4029 VNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLD 4088
Query: 3651 VPNSAVGRGAHVGVC 3665
+ S +G +G C
Sbjct: 4089 LTYSFLG-SQGIGQC 4102
Score = 39.1 bits (87), Expect = 0.30
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 21/147 (14%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT G +L+ G G + D++ +G+Q+G+ +G AR+ +
Sbjct: 4235 RTSTASGLLLWQGVEVG---EAGQGKDFISLGLQDGHLVFRYQLGSGE------ARLVSE 4285
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
+ D W++V R GRR + + +G + + + PG + N K +Y+
Sbjct: 4286 DPINDGEWHRVTALREGRRGSIQV-----DGEELVSGRS---PGPNVAVN---AKGSVYI 4334
Query: 2790 GGVPSDAKLQGISFPA-FEGQIEELMI 2815
GG P A L G F + G ++ L++
Sbjct: 4335 GGAPDVATLTGGRFSSGITGCVKNLVL 4361
Score = 38.7 bits (86), Expect = 0.39
Identities = 30/134 (22%), Positives = 45/134 (33%), Gaps = 18/134 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C C + + CE C C+ + G QC+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN------GHSDLCHPETGACSQCQ 1583
Query: 665 DRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKSG---QC-VCKQ 718
G C C P Y+ + P C+ C C L N C + +C C+
Sbjct: 1584 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1643
Query: 719 HVGERQCDQCLDGF 732
+ C+QC G+
Sbjct: 1644 GYTGQYCEQCGPGY 1657
Score = 37.5 bits (83), Expect = 0.90
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 1932 CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
C G D +S++ CVC G G +C+ + L C P CG + D
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEH--------SQALHCHPEACGPDATCVNRPD 3904
Query: 1991 DNG-QCRCAKGVTGKQCDQ 2008
G CRC G +G +C++
Sbjct: 3905 GRGYTCRCHLGRSGLRCEE 3923
Score = 37.1 bits (82), Expect = 1.2
Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 9/118 (7%)
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQCRCAKGVTGKQCDQCAA 2011
V G D P+ G + L C+C C D D G R G+ C++C+
Sbjct: 1102 VSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSC 1161
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATG-QCE-CLPGVIGEKCDRCPERWVLIPQEG 2067
+ C TG G + G +CE C PG G+ P+ L P G
Sbjct: 1162 ------HGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG 1213
Score = 37.1 bits (82), Expect = 1.2
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 13/83 (15%)
Query: 1737 QCPRAYRGLSCEQCAEGHYR-LPSGF---CVPCQC------NGHSDQCD-VNTG--ICLN 1783
QC G CE CA G+Y +G C PC C N S C+ + G C
Sbjct: 1581 QCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTA 1640
Query: 1784 CADNTIGDHCEFCMSGYHGDATV 1806
C G +CE C GY G+ +V
Sbjct: 1641 CEPGYTGQYCEQCGPGYVGNPSV 1663
Score = 36.3 bits (80), Expect = 2.1
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 12/94 (12%)
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCV 546
G + PTC+ C G + + S C+C AGF G RC+ + Q L C
Sbjct: 3841 GISHCPTCRDRPCQNGG-QCHDSESSSYVCVCPAGFTGSRCE------HSQAL----HCH 3889
Query: 547 PCNCDPTGSTSTSCSADG-KCNCLTNFGGAQCDQ 579
P C P + G C C G +C++
Sbjct: 3890 PEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEE 3923
Score = 34.7 bits (76), Expect = 6.4
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 15/130 (11%)
Query: 1269 TSKGVWLDYVLVIEASDFTDAVLTEANILDYTR-----EFIEQCASYNYYISPNETGL-C 1322
T G++L + + E + +D E + EF E CA Y + T C
Sbjct: 1551 TGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDC 1610
Query: 1323 REAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPN 1382
+ +T+ N +R C + +G+ C C+P G+ C C GY G P+
Sbjct: 1611 QPCACPLTNPENMFSRTC--ESLGAGGYRCTA------CEPGYTGQYCEQCGPGYVGNPS 1662
Query: 1383 CRPCHC-PST 1391
+ C P T
Sbjct: 1663 VQGGQCLPET 1672
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 319 bits (784), Expect = 1e-85
Identities = 197/549 (35%), Positives = 255/549 (46%), Gaps = 55/549 (10%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPS-TAICD-DNGMCI-CPKNVEG 1408
QC C P G +C C TGY P+ C C C + C+ + G C C + EG
Sbjct: 1127 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1186
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQLQ-CEADSG---KC-ACRENVRG 1459
C++C+P + D QRG C C C G C D+ C AC G
Sbjct: 1187 PRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSG 1245
Query: 1460 RVCDHCVPGHYAFPD----CYQ---------CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
R C+ C PG+Y P C + C C+ G+ CD QC CK V G
Sbjct: 1246 RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGL 1304
Query: 1507 ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVD----VLIN 1562
C C+ +F+L NPDGC CFC G T +C+SS YT I + P D L+N
Sbjct: 1305 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLIS--THFAPGDFQGFALVN 1362
Query: 1563 --NTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTV 1620
L V + L+ G N + Y+ PE Y G ++ +YGG L YT+
Sbjct: 1363 PQRNSRLTGEFTVEPVPEGAQLSFG-NFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTL 1421
Query: 1621 HYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMP--WTHSVKLSEEEFSTLDGAPV 1678
YT G ++ PDV I G N LV QP + P ++ + EE + DG P
Sbjct: 1422 SYTAGPQGSPLSDPDVQITGNNIMLV---ASQPALQGPERRSYEIMFREEFWRRPDGQPA 1478
Query: 1679 TRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQC 1738
TR+ + AL ++ L IRA++ + S+S V LE+ RA VEEC+C
Sbjct: 1479 TREHLLMALADLDELLIRATFSSVPLVASISAVSLEVAQPGPSNRP----RALEVEECRC 1534
Query: 1739 PRAYRGLSCEQCAEGHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
P Y GLSC+ CA G+ R SG C C+CNGHSD C TG C C N G+ CE
Sbjct: 1535 PPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCE 1594
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
C GY+GDAT GTP DC CACP+ P N F+ +C+ G C+PGY G CE
Sbjct: 1595 LCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQ 1654
Query: 1855 CAAGYYGIP 1863
C GY G P
Sbjct: 1655 CGPGYVGNP 1663
Score = 301 bits (739), Expect = 3e-80
Identities = 194/607 (31%), Positives = 266/607 (43%), Gaps = 41/607 (6%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPSTAI-CDD-NGMCI-CPKNVEG 1408
+C C G +C +C + P C C C A CD G C+ C N EG
Sbjct: 732 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDPVYGHCLNCQHNTEG 791
Query: 1409 ENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ----CEADS---GKC-ACRENVRGR 1460
C +CK F ++ C P + + C D+ C AC GR
Sbjct: 792 PQCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 851
Query: 1461 VCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ------CYCKTNVRGQACDTCKEE 1514
C+ C PG+ P C CD+ + C CK NV G+ C+ C +
Sbjct: 852 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADR 911
Query: 1515 YFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVP 1574
F+L NPDGC KCFC G + C+SS ++ A + + P + N H
Sbjct: 912 SFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASE-EPGHFSLTNAAS--THTTNE 968
Query: 1575 ELTNVTVLTVGLNDGVTNGKVAYF-GAPEYYLGKRLTSYGGYLTYTVHYTTR-GDGDAVA 1632
+ + T +G + YF P +LG ++TSYGG L +TV ++ G
Sbjct: 969 GIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHG 1028
Query: 1633 APDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISG 1692
P V++ G N L H+ ++P G P T V E+ + DG P TR+ + AL I
Sbjct: 1029 QPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDT 1088
Query: 1693 LYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAE 1752
L IRASY + E+ +S + +++ V G + A VE+C CP YRG SC+ C
Sbjct: 1089 LLIRASYAQQPAESRVSGISMDVAVPEETGQD----PALEVEQCSCPPGYRGPSCQDCDT 1144
Query: 1753 GHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGT 1808
G+ R PSG C C C+GHS+ C+ TG C C +T G CE C GY+GDA GT
Sbjct: 1145 GYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGT 1204
Query: 1809 PRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDL 1868
P+DC +C C + A +C L +G C PG+ G CE CA GYYG P
Sbjct: 1205 PQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQP 1264
Query: 1869 HTGDYCKPCNCSGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCAP-GFYGDAIFSK 1925
D P N +PQ S CD+ G C +C G C+ C P F+ A
Sbjct: 1265 CQRDSQVPGPIGCNCDPQGSVSSQCDAA-GQC-QCKAQVEGLTCSHCRPHHFHLSASNPD 1322
Query: 1926 NCTACIC 1932
C C C
Sbjct: 1323 GCLPCFC 1329
Score = 216 bits (527), Expect = 1e-54
Identities = 141/439 (32%), Positives = 195/439 (44%), Gaps = 24/439 (5%)
Query: 1506 QACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI----DEMVDWYPVDVLI 1561
Q C + +F L+ + C CFCFG T+ C S+ I D+ D+ V+V +
Sbjct: 502 QRAGPCPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTM 559
Query: 1562 NNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKV--AYFGAPEYYLGKRLTSYGGYLTYT 1619
P + ++ L D V +++ PE +LG ++ SYGG L Y
Sbjct: 560 PAQPGTPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYN 619
Query: 1620 VHYT-TRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPV 1678
V Y RG + V PDV++ G L+ G V+ SEE + G PV
Sbjct: 620 VRYELARGMLEPVQRPDVVLVGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPV 679
Query: 1679 TRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQC 1738
R + + L ++ + I+ Y LS++ ++ V + RA SVEEC+C
Sbjct: 680 QRAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHG----RAHSVEECRC 735
Query: 1739 PRAYRGLSCEQCAEGHYRLPSG----FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
P Y GLSCE C R+P G C C CNGH+ CD G CLNC NT G C+
Sbjct: 736 PIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDPVYGHCLNCQHNTEGPQCK 795
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
C +G+ GDA T C C CP S F+ +C L +G C PGY G RCE
Sbjct: 796 KCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCES 855
Query: 1855 CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCA 1914
CA GY G P + G C+P N + + GS + +G+ +C NN G CN CA
Sbjct: 856 CAPGYEGNP----IQPGGKCRPVN-QEIVRCDERGSMGT-SGEACRCKNNVVGRLCNECA 909
Query: 1915 P-GFYGDAIFSKNCTACIC 1932
F+ C C C
Sbjct: 910 DRSFHLSTRNPDGCLKCFC 928
Score = 112 bits (270), Expect = 2e-23
Identities = 71/208 (34%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S+ C C GY G CE C A + +P L T C C+C+G+ + SCD + G
Sbjct: 729 SVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGT---CSGCSCNGHAS-----SCDPVYG 780
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTT--------GT 1946
CL C +NT G C C GF+GDA+ + +C C C + S T T
Sbjct: 781 HCLNCQHNTEGPQCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 840
Query: 1947 C-VCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGI--ASESTQCDDDNGQCRCAKGV 2001
C C PG G +C+ CAP + G + G C P N I E CRC V
Sbjct: 841 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNV 900
Query: 2002 TGKQCDQCA-AGFWNYTK--DGCDHCNC 2026
G+ C++CA F T+ DGC C C
Sbjct: 901 VGRLCNECADRSFHLSTRNPDGCLKCFC 928
Score = 111 bits (268), Expect = 3e-23
Identities = 67/202 (33%), Positives = 88/202 (43%), Gaps = 32/202 (15%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C+C Y G +C C GY P TC+ C+C C+ +G C C+
Sbjct: 1128 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHS---EACEPETGACQGCQHHT 1184
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNC--DPT-GSTSTSC--SADGK--CN-CLTNFG 573
GPRC+QC GYY G + C C C DP G + +C DG C+ C
Sbjct: 1185 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1244
Query: 574 GAQCDQCSPGYYKYPD----C---------LSCNCDVSGSIGSTCDDNGLCHCKSNFDGA 620
G C++C+PGYY P C + CNCD GS+ S CD G C CK+ +G
Sbjct: 1245 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 1304
Query: 621 KCDTCREQFYNYPACEECNCDP 642
C CR ++ A C P
Sbjct: 1305 TCSHCRPHHFHLSASNPDGCLP 1326
Score = 102 bits (245), Expect = 2e-20
Identities = 72/226 (31%), Positives = 103/226 (45%), Gaps = 41/226 (18%)
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTST 558
+ +G +P++ +V QC C G+ GP C C +GY G C C+C S
Sbjct: 1115 EETGQDPAL--EVE-QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSE 1168
Query: 559 SCSAD-GKCN-CLTNFGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC-- 605
+C + G C C + G +C+QC PGYY DC C C +G TC
Sbjct: 1169 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFL 1228
Query: 606 --DDNGLCH-CKSNFDGAKCDTCREQFYNYPA----CEE---------CNCDPRGVTASF 649
D + C C G C+ C +Y P+ C+ CNCDP+G +S
Sbjct: 1229 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS- 1287
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C + AG+ CQCK +V+G C+ C+P +++L NP GC C C
Sbjct: 1288 -QCDA--AGQ-CQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1329
Score = 101 bits (242), Expect = 5e-20
Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 38/210 (18%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLCP-C 427
E +C C P ++ P C C GY P+ C+ C+C+ E C P G C C
Sbjct: 1124 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGC 1180
Query: 428 KYNYAGKSCEICEDGYYS-------PECKNCEC---NTVGSVSYVCDKLT-GDCTCKS-- 474
+++ G CE C+ GYY +C+ C C G ++ C T G TC +
Sbjct: 1181 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1240
Query: 475 -KYSGRTCNQCQAGYYNYPT----CK---------PCNCDTSGTEPSICDDVSGQCICKA 520
+SGR C +C GYY P+ C+ CNCD G+ S C D +GQC CKA
Sbjct: 1241 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAAGQCQCKA 1299
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
G C C ++ C+PC C
Sbjct: 1300 QVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1329
Score = 92.7 bits (220), Expect = 2e-17
Identities = 61/202 (30%), Positives = 87/202 (43%), Gaps = 26/202 (12%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKC-NCLTN 571
+C C G+ G C+ C ++ +V G C C+C+ G S+ G C NC N
Sbjct: 732 ECRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCSCN--GHASSCDPVYGHCLNCQHN 788
Query: 572 FGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC----DDNGLCH-CKSNF 617
G QC +C G++ C C C D S TC D C C +
Sbjct: 789 TEGPQCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 848
Query: 618 DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC---GSV-PAGELCQCKDRVQGRICN 673
G +C++C + P C P V C GS+ +GE C+CK+ V GR+CN
Sbjct: 849 TGRRCESCAPGYEGNPIQPGGKCRP--VNQEIVRCDERGSMGTSGEACRCKNNVVGRLCN 906
Query: 674 DCKPLYWNLQEYNPFGCEQCNC 695
+C ++L NP GC +C C
Sbjct: 907 ECADRSFHLSTRNPDGCLKCFC 928
Score = 87.0 bits (206), Expect = 1e-15
Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C PGY G C+ CA GY + L+ G +C+ C C+G+ + C G C +
Sbjct: 1532 CRCPPGYIGLSCQDCAPGY--TRTGSGLYLG-HCELCECNGHSD-----LCHPETGACSQ 1583
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFS--KNCTACIC-----DEFGMADCDSTTG---TC-VC 1949
C +N AG C LCAPG+YGDA ++C C C + C+S C C
Sbjct: 1584 CQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTAC 1643
Query: 1950 RPGVIGEKCDRCAPDHWG 1967
PG G+ C++C P + G
Sbjct: 1644 EPGYTGQYCEQCGPGYVG 1661
Score = 86.2 bits (204), Expect = 2e-15
Identities = 65/222 (29%), Positives = 93/222 (41%), Gaps = 38/222 (17%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCE-CRPEF 385
+C G +C C Y R + L C+ C C H CE E+G C+ C+
Sbjct: 1129 SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGHSEA--CEPETGACQGCQHHT 1184
Query: 386 QPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE--H-C-TPTDG--LCP-CKYNYA 432
+ P C C GY+ +C+ C C + G+ H C TDG C C ++
Sbjct: 1185 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1244
Query: 433 GKSCEICEDGYY-SPE----CKN---------CECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G+ CE C GYY +P C+ C C+ GSVS CD G C CK++ G
Sbjct: 1245 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEG 1303
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
TC+ C+ +++ P C P C ++ QC A
Sbjct: 1304 LTCSHCRPHHFHLSASNPDGC-----LPCFCMGITQQCASSA 1340
Score = 85.0 bits (201), Expect = 5e-15
Identities = 60/215 (27%), Positives = 91/215 (42%), Gaps = 29/215 (13%)
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDS 1942
P++ G ++ + C G +C C G+ ++ C C C A C+
Sbjct: 1114 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA-CEP 1172
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC------GIASESTQCDDD- 1991
TG C C+ G +C++C P ++G T C C C G A+ + D D
Sbjct: 1173 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDG 1232
Query: 1992 NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---------CNCNTGYSVGFMCNAT 2039
+ C C+ G +G+ C++CA G++ G C CNC+ SV C+A
Sbjct: 1233 HPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA 1292
Query: 2040 GQCECLPGVIGEKCDRC-PERWVLIPQ--EGCLEC 2071
GQC+C V G C C P + L +GCL C
Sbjct: 1293 GQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 1327
Score = 79.4 bits (187), Expect = 2e-13
Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 26/205 (12%)
Query: 316 NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE 375
+GR +C C G++C C + R G + L C C C+ H S+ C+
Sbjct: 724 HGRAHSVEEC-RCPIGYSGLSCESCDAHFTRVPGGPY--LGTCSGCSCNGHASS--CDPV 778
Query: 376 SGRC-ECRPEFQPPDCSSCAYGYFD------YPNCKPCTC---NLNGTEGEHC-TPTDGL 424
G C C+ + P C C G+F +C+PC C + + + C TDG
Sbjct: 779 YGHCLNCQHNTEGPQCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQ 838
Query: 425 CPCKY---NYAGKSCEICEDGYY-SPECKNCECNTVGSVSYVCDK-----LTGD-CTCKS 474
C Y G+ CE C GY +P +C V CD+ +G+ C CK+
Sbjct: 839 ATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKN 898
Query: 475 KYSGRTCNQCQAGYYNYPTCKPCNC 499
GR CN+C ++ T P C
Sbjct: 899 NVVGRLCNECADRSFHLSTRNPDGC 923
Score = 78.2 bits (184), Expect = 5e-13
Identities = 69/248 (27%), Positives = 94/248 (37%), Gaps = 52/248 (20%)
Query: 244 DPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYD 303
DPA L + C C GP C C +G+ R +CE C+CH H+ C +
Sbjct: 1120 DPA--LEVEQCSCPPGYRGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--E 1171
Query: 304 PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC 363
PE G C CQH+TEG C +C+P YY +R D CQ C C
Sbjct: 1172 PET----------------GACQGCQHHTEGPRCEQCQPGYYGD-AQRGTPQD-CQLCPC 1213
Query: 364 --DPHF--STGNC---EEESGRCE-CRPEFQPPDCSSCAYGYFDYPN----CK------- 404
DP + C + C+ C P C CA GY+ P+ C+
Sbjct: 1214 YGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 1273
Query: 405 --PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
C C+ G+ C G C CK G +C C ++ N + G +
Sbjct: 1274 PIGCNCDPQGSVSSQCDAA-GQCQCKAQVEGLTCSHCRPHHFHLSASNPD----GCLPCF 1328
Query: 463 CDKLTGDC 470
C +T C
Sbjct: 1329 CMGITQQC 1336
Score = 77.4 bits (182), Expect = 9e-13
Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 1160 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 1208
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + + ++ +G C C G +C +C P YY P
Sbjct: 1209 QLCPCYG-------DPAAGQAAHTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNP 1259
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----- 398
+ + D P C CDP S + + +G+C+C+ + + CS C +F
Sbjct: 1260 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSAS 1319
Query: 399 DYPNCKPCTC 408
+ C PC C
Sbjct: 1320 NPDGCLPCFC 1329
Score = 77.0 bits (181), Expect = 1e-12
Identities = 65/235 (27%), Positives = 89/235 (37%), Gaps = 42/235 (17%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC G C C + F R+ +C C+C+ H + C DP
Sbjct: 733 CRCPIGYSGLSCESCDAHFT----RVPGGPYLGTCSGCSCNGHASSC--DPVY------- 779
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC-----DPHFS 368
G CLNCQHNTEG C KC+ ++ K C+PC C FS
Sbjct: 780 ---------GHCLNCQHNTEGPQCKKCKAGFFGDAMKA--TATSCRPCPCPYIDASRRFS 828
Query: 369 TGNCEEESGR--CE-CRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHCTP 420
+ G+ C+ C P + C SCA GY P C+P + +
Sbjct: 829 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMG 888
Query: 421 TDG-LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKS 474
T G C CK N G+ C C D + +N + G + C ++ CT S
Sbjct: 889 TSGEACRCKNNVVGRLCNECADRSFHLSTRNPD----GCLKCFCMGVSRHCTSSS 939
Score = 75.8 bits (178), Expect = 3e-12
Identities = 54/202 (26%), Positives = 81/202 (40%), Gaps = 23/202 (11%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD------CLSCNCDVSGSIGSTCDD-NGLC-HCKSN 616
+C C + G C+ C + + P C C+C+ S+CD G C +C+ N
Sbjct: 732 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCN---GHASSCDPVYGHCLNCQHN 788
Query: 617 FDGAKCDTCREQFYN------YPACEECNCDPRGVTASFAG-CGSVPAGEL-CQ-CKDRV 667
+G +C C+ F+ +C C C + F+ C G+ C C
Sbjct: 789 TEGPQCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 848
Query: 668 QGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
GR C C P Y P G C N + + G+ T C CK +V R C+
Sbjct: 849 TGRRCESCAPGYEG-NPIQPGGKCRPVNQEIV-RCDERGSMGTSGEACRCKNNVVGRLCN 906
Query: 727 QCLDGFYRLQTNDVFGCTECDC 748
+C D + L T + GC +C C
Sbjct: 907 ECADRSFHLSTRNPDGCLKCFC 928
Score = 74.9 bits (176), Expect = 5e-12
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPDCL---SCN-CDVSGSIGSTCDDNGLCH-CKSNFDG 619
+C+C + G C C GY + P L +C C G + + G C C+ + +G
Sbjct: 1127 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1186
Query: 620 AKCDTCREQFYNYPA------CEECNC--DPRGVTASFAGCGSVPAGELCQ-CKDRVQGR 670
+C+ C+ +Y C+ C C DP A+ C C GR
Sbjct: 1187 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1246
Query: 671 ICNDCKPLYW-NLQEYNPF-------GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C C P Y+ N + P G CNC+ G+++S C+ +GQC CK V
Sbjct: 1247 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS--QCDA-AGQCQCKAQVEG 1303
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDC 748
C C + L ++ GC C C
Sbjct: 1304 LTCSHCRPHHFHLSASNPDGCLPCFC 1329
Score = 73.7 bits (173), Expect = 1e-11
Identities = 48/146 (32%), Positives = 64/146 (43%), Gaps = 24/146 (16%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGY------FDYPNCKPCTCNLNGTEGEHCTPTDGLCP-C 427
E C C P + C CA GY +C+ C CN + C P G C C
Sbjct: 1528 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQC 1584
Query: 428 KYNYAGKSCEICEDGYY------SPE-CKNCEC---NTVGSVSYVCDKLTGD---CT-CK 473
++N AG+ CE+C GYY +PE C+ C C N S C+ L CT C+
Sbjct: 1585 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACE 1644
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNC 499
Y+G+ C QC GY P+ + C
Sbjct: 1645 PGYTGQYCEQCGPGYVGNPSVQGGQC 1670
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/196 (27%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQ-C 663
C C + G C C + P+ CE C+C P CQ C
Sbjct: 1128 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE-------PETGACQGC 1180
Query: 664 KDRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCN---LAGTLNSLGACNTKSGQ-C-VCK 717
+ +G C C+P Y+ + Q P C+ C C AG +T C C
Sbjct: 1181 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1240
Query: 718 QHVGERQCDQCLDGFYR--------LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHS 769
R C++C G+Y + + V G C+CD GS+ + CD GQC C +
Sbjct: 1241 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKA 1299
Query: 770 RVEGRRCDQPIRAHYF 785
+VEG C R H+F
Sbjct: 1300 QVEGLTCSH-CRPHHF 1314
Score = 70.5 bits (165), Expect = 1e-10
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 24/144 (16%)
Query: 425 CPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDCT-CKSKY 476
C C Y G SC+ C GY Y C+ CECN S +C TG C+ C+
Sbjct: 1532 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQCQHNA 1588
Query: 477 SGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSI---CDDVSG---QCI-CKAGFG 523
+G C C GYY T C+PC C + E C+ + +C C+ G+
Sbjct: 1589 AGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYT 1648
Query: 524 GPRCDQCLSGYYMQVLGRERQCVP 547
G C+QC GY + QC+P
Sbjct: 1649 GQYCEQCGPGYVGNPSVQGGQCLP 1672
Score = 67.3 bits (157), Expect = 1e-09
Identities = 54/197 (27%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 1900 KCVNNTAGAACNLCAPGF--YGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGE 1956
+C +G +C C F + C+ C C+ + CD G C+ C+ G
Sbjct: 734 RCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHA-SSCDPVYGHCLNCQHNTEGP 792
Query: 1957 KCDRCAPDHWG---LNTGLGCTPCNCGIASESTQCDDD-----NGQCRC---AKGVTGKQ 2005
+C +C +G T C PC C S + D +GQ C A G TG++
Sbjct: 793 QCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRR 852
Query: 2006 CDQCAAGF-WNYTKDG--CDHCN-----CNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
C+ CA G+ N + G C N C+ S+G A C C V+G C+ C
Sbjct: 853 CESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEA---CRCKNNVVGRLCNECA 909
Query: 2058 ERWVLIP---QEGCLEC 2071
+R + +GCL+C
Sbjct: 910 DRSFHLSTRNPDGCLKC 926
Score = 66.9 bits (156), Expect = 1e-09
Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 19/143 (13%)
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
+C C Y G +C C GY + C+ C C+ +C +G C C+
Sbjct: 1531 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHS---DLCHPETGACSQCQHN 1587
Query: 522 FGGPRCDQCLSGYYMQVL-GRERQCVPCNC---DPTGSTSTSCSADG----KCN-CLTNF 572
G C+ C GYY G C PC C +P S +C + G +C C +
Sbjct: 1588 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1647
Query: 573 GGAQCDQCSPGYYKYPDCLSCNC 595
G C+QC PGY P C
Sbjct: 1648 TGQYCEQCGPGYVGNPSVQGGQC 1670
Score = 65.7 bits (153), Expect = 3e-09
Identities = 53/210 (25%), Positives = 76/210 (36%), Gaps = 30/210 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C C + C SC + P C C+CN + + C P G C C++N
Sbjct: 733 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASS---CDPVYGHCLNCQHNT 789
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKL----TGDCTCKS---KYS 477
G C+ C+ G++ + C+ C C + + D G TC + Y+
Sbjct: 790 EGPQCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYT 849
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD-----VSGQ-CICKAGFGGPRCDQCL 531
GR C C GY P C E CD+ SG+ C CK G C++C
Sbjct: 850 GRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECA 909
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
+ C+ C C TS S
Sbjct: 910 DRSFHLSTRNPDGCLKCFCMGVSRHCTSSS 939
Score = 65.3 bits (152), Expect = 4e-09
Identities = 60/197 (30%), Positives = 72/197 (36%), Gaps = 34/197 (17%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGHA +C+P G+ CQHNT GPQC KC +GF + + SC P
Sbjct: 766 CSCNGHASSCDPV--YGHC----LNCQHNTEGPQCKKCKAGFFGDAMKATAT----SCRP 815
Query: 291 CNCHNHTTECTYDPEID-EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C P ID +R S +G C C G C C P Y G
Sbjct: 816 CPC----------PYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY---EG 862
Query: 350 KRWDELDVCQP-----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
C+P +CD S G E C C+ C+ CA F
Sbjct: 863 NPIQPGGKCRPVNQEIVRCDERGSMGTSGE---ACRCKNNVVGRLCNECADRSFHLSTRN 919
Query: 405 PCTCNLNGTEG--EHCT 419
P C G HCT
Sbjct: 920 PDGCLKCFCMGVSRHCT 936
Score = 62.9 bits (146), Expect = 2e-08
Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN-CGIASESTQCDDDNGQC-RCAKGVTGK 2004
C C PG IG C CAP + +GL C C S C + G C +C G+
Sbjct: 1532 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGE 1591
Query: 2005 QCDQCAAGFWN----YTKDGCDHCNC---NTGYSVGFMCNATG----QC-ECLPGVIGEK 2052
C+ CA G++ T + C C C N C + G +C C PG G+
Sbjct: 1592 FCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQY 1651
Query: 2053 CDRCPERWV 2061
C++C +V
Sbjct: 1652 CEQCGPGYV 1660
Score = 61.3 bits (142), Expect = 6e-08
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 16/140 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC-ECRPEFQ 386
C G++C C P Y R + L C+ C+C+ H + C E+G C +C+
Sbjct: 1534 CPPGYIGLSCQDCAPGYTRTGSGLY--LGHCELCECNGH--SDLCHPETGACSQCQHNAA 1589
Query: 387 PPDCSSCAYGYF------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C CA GY+ +C+PC C L E + L G C CE
Sbjct: 1590 GEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESL-----GAGGYRCTACE 1644
Query: 441 DGYYSPECKNCECNTVGSVS 460
GY C+ C VG+ S
Sbjct: 1645 PGYTGQYCEQCGPGYVGNPS 1664
Score = 58.0 bits (134), Expect = 6e-07
Identities = 49/175 (28%), Positives = 70/175 (40%), Gaps = 31/175 (17%)
Query: 1340 CLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYG------FPNCRPCHCP--- 1389
C C+ S+ C+ G C C+ N G C C+ G++G +CRPC CP
Sbjct: 766 CSCNGHASS---CDPVYGHCLNCQHNTEGPQCKKCKAGFFGDAMKATATSCRPCPCPYID 822
Query: 1390 ------STAICDDNGMC---ICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGN 1440
T D +G C G C+ C P +Q G N V +
Sbjct: 823 ASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCD 882
Query: 1441 QLQCEADSGK-CACRENVRGRVCDHCVPGHYAF----PD-CYQCTC---NRHGTT 1486
+ SG+ C C+ NV GR+C+ C + PD C +C C +RH T+
Sbjct: 883 ERGSMGTSGEACRCKNNVVGRLCNECADRSFHLSTRNPDGCLKCFCMGVSRHCTS 937
Score = 58.0 bits (134), Expect = 6e-07
Identities = 49/175 (28%), Positives = 61/175 (34%), Gaps = 32/175 (18%)
Query: 242 PADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECT 301
P++ L + CRC G C C G+ R CE C C+ H+ C
Sbjct: 1520 PSNRPRALEVEECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLC- 1574
Query: 302 YDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
PE G C CQHN G C C P YY E CQPC
Sbjct: 1575 -HPET----------------GACSQCQHNAAGEFCELCAPGYYGDATAGTPE--DCQPC 1615
Query: 362 QC---DP-HFSTGNCEEESG---RC-ECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
C +P + + CE RC C P + C C GY P+ + C
Sbjct: 1616 ACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1670
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 19/141 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTA-ICD-DNGMCI-CPKNVEG 1408
+C C P IG +C C GY +C C C + +C + G C C N G
Sbjct: 1531 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAG 1590
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNC---NPLGVVGNQLQCEADSG-KC-ACRENVRG 1459
E C+ C P + D G C C C NP + + G +C AC G
Sbjct: 1591 EFCELCAPGYYG-DATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTG 1649
Query: 1460 RVCDHCVPGHYAFPDCYQCTC 1480
+ C+ C PG+ P C
Sbjct: 1650 QYCEQCGPGYVGNPSVQGGQC 1670
Score = 56.0 bits (129), Expect = 2e-06
Identities = 51/180 (28%), Positives = 84/180 (46%), Gaps = 19/180 (10%)
Query: 3022 SFNGTDSYLRFVDVTSENPQLTL--KFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGK 3079
S +G SYL +T+ + +L L +FK P+G+L S ++ + D +SL++V G
Sbjct: 3933 SLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLF--SGGKSGPVEDFVSLAMVGGH 3990
Query: 3080 LVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDG-- 3137
L R +L +GL ++ L H SA +L D + P L G
Sbjct: 3991 LEF---RYELGSGLAVLRTAEPLALGRWHRVSAERLNKDGS--LRVNGGRPVLRSSPGKS 4045
Query: 3138 -------VLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
+L++GGV+P +S + F GC+G+ ++NG+ L+L F S G+C
Sbjct: 4046 QGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL-GSQGIGQC 4104
Score = 49.2 bits (112), Expect = 3e-04
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 19/114 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH+D C P A +CQHN G C C G+ + + C+P
Sbjct: 1565 CECNGHSDLCHPETGA------CSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQP 1614
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C C +P E S GG +C C+ G C +C P Y
Sbjct: 1615 CACP------LTNP---ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGY 1659
Score = 48.8 bits (111), Expect = 4e-04
Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 21/182 (11%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C++C F P C C+C+ + C V G C+
Sbjct: 733 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHA-----SSCDPV-YGHCLNCQ 786
Query: 665 DRVQGRICNDCKP-LYWNLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKS-GQCVCKQ--- 718
+G C CK + + + C C C C + GQ C
Sbjct: 787 HNTEGPQCKKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 846
Query: 719 -HVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ-CHCHSRVEGRRC 776
+ G R+C+ C G+ C + +I + T+G+ C C + V GR C
Sbjct: 847 GYTG-RRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 905
Query: 777 DQ 778
++
Sbjct: 906 NE 907
Score = 48.0 bits (109), Expect = 6e-04
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK
Sbjct: 1249 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQ 1300
Query: 1365 VIGRTCSACRTGYYGF-----PNCRPCHC 1388
V G TCS CR ++ C PC C
Sbjct: 1301 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 1329
Score = 47.6 bits (108), Expect = 8e-04
Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 21/106 (19%)
Query: 1341 LCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF------PNCRPCHCPST-- 1391
LC+ G ++L C+ G C C+ N G C C GYYG +C+PC CP T
Sbjct: 1564 LCECNGHSDL-CHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNP 1622
Query: 1392 -----AICDDNG----MC-ICPKNVEGENCDRCKP-YTFNFDVQRG 1426
C+ G C C G+ C++C P Y N VQ G
Sbjct: 1623 ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGG 1668
Score = 47.6 bits (108), Expect = 8e-04
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 14/138 (10%)
Query: 3516 SISMEVRPRNTTGLLL-------SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSN 3568
+I +EVR +GLLL KD++ L L D +V + G+G R L +
Sbjct: 4231 TIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEAR----LVS 4286
Query: 3569 KHYLCDGNWHKIHXXXXXXXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKV 3626
+ + DG WH++ DG S G + + ++YIGG + +
Sbjct: 4287 EDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSIYIGGAP-DVATL 4345
Query: 3627 RGVHSRRGFTGCVRNIVV 3644
G G TGCV+N+V+
Sbjct: 4346 TGGRFSSGITGCVKNLVL 4363
Score = 47.2 bits (107), Expect = 0.001
Identities = 42/149 (28%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 2877 FRTYAPNG-LIYLVGEGGY---FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWH 2932
F+ AP+G L++ G+ G F SL M G + + LG+ L ++ T G+WH
Sbjct: 3959 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGS--GLAVLRTAEPLALGRWH 4016
Query: 2933 KLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNF-GGNNKGILQVPDRG----FD 2987
++ A R SL V+ S+ + +L T+ + GG + P F
Sbjct: 4017 RVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFR 4076
Query: 2988 GCMRQISINGVNLDLSENL---ESIGMAY 3013
GC+ ++S+NG LDL+ + + IG Y
Sbjct: 4077 GCVGEVSVNGKRLDLTYSFLGSQGIGQCY 4105
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 2890 GEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD- 2948
G+G F SL +QDG + + LG+ E ++ + NDG+WH++ A R + S+ VD
Sbjct: 4256 GQGKDFISLGLQDGHLVFRYQLGSGEARLV--SEDPINDGEWHRVTALREGRRGSIQVDG 4313
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDR---GFDGCMRQISIN 2996
E++ S P+ + + ++ GG R G GC++ + ++
Sbjct: 4314 EELVSGRSPGPNVAVNAKGSIYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4364
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 3361 FLAFFMRDAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVD-SEMVGET 3419
F++ ++D L + + G + S ND +WH VT R G G + VD E+V
Sbjct: 4261 FISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGR 4320
Query: 3420 SVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMN 3466
S N ++ Y GG V + F GC+K L+++
Sbjct: 4321 SPGPNVAVNAKGSIYIGGAPDV---ATLTGGRFSSGITGCVKNLVLH 4364
Score = 43.2 bits (97), Expect = 0.018
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 8/95 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQC-VC 716
E C+C G C DC P Y G CE C CN L C+ ++G C C
Sbjct: 1530 EECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL-----CHPETGACSQC 1584
Query: 717 KQHVGERQCDQCLDGFYRLQT-NDVFGCTECDCDI 750
+ + C+ C G+Y T C C C +
Sbjct: 1585 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPL 1619
Score = 42.7 bits (96), Expect = 0.024
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 15/72 (20%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKDG-------CDHCNCNTGYSVGFMCN-ATGQC-EC 2044
+CRC G G C CA G YT+ G C+ C CN G+S +C+ TG C +C
Sbjct: 1531 ECRCPPGYIGLSCQDCAPG---YTRTGSGLYLGHCELCECN-GHS--DLCHPETGACSQC 1584
Query: 2045 LPGVIGEKCDRC 2056
GE C+ C
Sbjct: 1585 QHNAAGEFCELC 1596
Score = 39.5 bits (88), Expect = 0.22
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 21/147 (14%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT G +L+ G G + D++ +G+Q+G+ +G AR+ +
Sbjct: 4237 RTSTASGLLLWQGVEVG---EAGQGKDFISLGLQDGHLVFRYQLGSGE------ARLVSE 4287
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
+ D W++V R GRR + + +G + + + PG + N K +Y+
Sbjct: 4288 DPINDGEWHRVTALREGRRGSIQV-----DGEELVSGRS---PGPNVAVN---AKGSIYI 4336
Query: 2790 GGVPSDAKLQGISFPA-FEGQIEELMI 2815
GG P A L G F + G ++ L++
Sbjct: 4337 GGAPDVATLTGGRFSSGITGCVKNLVL 4363
Score = 38.7 bits (86), Expect = 0.39
Identities = 30/134 (22%), Positives = 45/134 (33%), Gaps = 18/134 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C C + + CE C C+ + G QC+
Sbjct: 1532 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN------GHSDLCHPETGACSQCQ 1585
Query: 665 DRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKSG---QC-VCKQ 718
G C C P Y+ + P C+ C C L N C + +C C+
Sbjct: 1586 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1645
Query: 719 HVGERQCDQCLDGF 732
+ C+QC G+
Sbjct: 1646 GYTGQYCEQCGPGY 1659
Score = 38.7 bits (86), Expect = 0.39
Identities = 45/195 (23%), Positives = 75/195 (38%), Gaps = 16/195 (8%)
Query: 3478 NALRCVDNIEDGVYFEA-SNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGK 3536
+ LRC E+GV S + +YL L E+ + +E +P G+LL GK
Sbjct: 3919 SGLRC----EEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGK 3974
Query: 3537 ----KDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXX 3592
+D++ L ++ + E G+G L L G WH++
Sbjct: 3975 SGPVEDFVSLAMVGGHLEFRYELGSG----LAVLRTAEPLALGRWHRVSAERLNKDGSLR 4030
Query: 3593 XDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVK 3650
+G + G + H+ LY+GG E + + F GCV + V +
Sbjct: 4031 VNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLD 4090
Query: 3651 VPNSAVGRGAHVGVC 3665
+ S +G +G C
Sbjct: 4091 LTYSFLG-SQGIGQC 4104
Score = 37.5 bits (83), Expect = 0.90
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 1932 CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
C G D +S++ CVC G G +C+ + L C P CG + D
Sbjct: 3855 CQNGGQCHDSESSSYVCVCPAGFTGSRCEH--------SQALHCHPEACGPDATCVNRPD 3906
Query: 1991 DNG-QCRCAKGVTGKQCDQ 2008
G CRC G +G +C++
Sbjct: 3907 GRGYTCRCHLGRSGLRCEE 3925
Score = 37.1 bits (82), Expect = 1.2
Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 9/118 (7%)
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQCRCAKGVTGKQCDQCAA 2011
V G D P+ G + L C+C C D D G R G+ C++C+
Sbjct: 1104 VSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSC 1163
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATG-QCE-CLPGVIGEKCDRCPERWVLIPQEG 2067
+ C TG G + G +CE C PG G+ P+ L P G
Sbjct: 1164 ------HGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG 1215
Score = 37.1 bits (82), Expect = 1.2
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 13/83 (15%)
Query: 1737 QCPRAYRGLSCEQCAEGHYR-LPSGF---CVPCQC------NGHSDQCD-VNTG--ICLN 1783
QC G CE CA G+Y +G C PC C N S C+ + G C
Sbjct: 1583 QCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTA 1642
Query: 1784 CADNTIGDHCEFCMSGYHGDATV 1806
C G +CE C GY G+ +V
Sbjct: 1643 CEPGYTGQYCEQCGPGYVGNPSV 1665
Score = 36.3 bits (80), Expect = 2.1
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 12/94 (12%)
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCV 546
G + PTC+ C G + + S C+C AGF G RC+ + Q L C
Sbjct: 3843 GISHCPTCRDRPCQNGG-QCHDSESSSYVCVCPAGFTGSRCE------HSQAL----HCH 3891
Query: 547 PCNCDPTGSTSTSCSADG-KCNCLTNFGGAQCDQ 579
P C P + G C C G +C++
Sbjct: 3892 PEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEE 3925
Score = 34.7 bits (76), Expect = 6.4
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 15/130 (11%)
Query: 1269 TSKGVWLDYVLVIEASDFTDAVLTEANILDYTR-----EFIEQCASYNYYISPNETGL-C 1322
T G++L + + E + +D E + EF E CA Y + T C
Sbjct: 1553 TGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDC 1612
Query: 1323 REAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPN 1382
+ +T+ N +R C + +G+ C C+P G+ C C GY G P+
Sbjct: 1613 QPCACPLTNPENMFSRTC--ESLGAGGYRCTA------CEPGYTGQYCEQCGPGYVGNPS 1664
Query: 1383 CRPCHC-PST 1391
+ C P T
Sbjct: 1665 VQGGQCLPET 1674
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 319 bits (784), Expect = 1e-85
Identities = 197/549 (35%), Positives = 255/549 (46%), Gaps = 55/549 (10%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPS-TAICD-DNGMCI-CPKNVEG 1408
QC C P G +C C TGY P+ C C C + C+ + G C C + EG
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQLQ-CEADSG---KC-ACRENVRG 1459
C++C+P + D QRG C C C G C D+ C AC G
Sbjct: 1185 PRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSG 1243
Query: 1460 RVCDHCVPGHYAFPD----CYQ---------CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
R C+ C PG+Y P C + C C+ G+ CD QC CK V G
Sbjct: 1244 RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGL 1302
Query: 1507 ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVD----VLIN 1562
C C+ +F+L NPDGC CFC G T +C+SS YT I + P D L+N
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLIS--THFAPGDFQGFALVN 1360
Query: 1563 --NTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTV 1620
L V + L+ G N + Y+ PE Y G ++ +YGG L YT+
Sbjct: 1361 PQRNSRLTGEFTVEPVPEGAQLSFG-NFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTL 1419
Query: 1621 HYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMP--WTHSVKLSEEEFSTLDGAPV 1678
YT G ++ PDV I G N LV QP + P ++ + EE + DG P
Sbjct: 1420 SYTAGPQGSPLSDPDVQITGNNIMLV---ASQPALQGPERRSYEIMFREEFWRRPDGQPA 1476
Query: 1679 TRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQC 1738
TR+ + AL ++ L IRA++ + S+S V LE+ RA VEEC+C
Sbjct: 1477 TREHLLMALADLDELLIRATFSSVPLVASISAVSLEVAQPGPSNRP----RALEVEECRC 1532
Query: 1739 PRAYRGLSCEQCAEGHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
P Y GLSC+ CA G+ R SG C C+CNGHSD C TG C C N G+ CE
Sbjct: 1533 PPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCE 1592
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
C GY+GDAT GTP DC CACP+ P N F+ +C+ G C+PGY G CE
Sbjct: 1593 LCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQ 1652
Query: 1855 CAAGYYGIP 1863
C GY G P
Sbjct: 1653 CGPGYVGNP 1661
Score = 301 bits (739), Expect = 3e-80
Identities = 194/607 (31%), Positives = 267/607 (43%), Gaps = 41/607 (6%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPSTAI-CDD-NGMCI-CPKNVEG 1408
+C C G +C +C + P C C C A CD G C+ C N EG
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDPVYGHCLNCQHNTEG 789
Query: 1409 ENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ----CEADS---GKC-ACRENVRGR 1460
C++CK F ++ C P + + C D+ C AC GR
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 849
Query: 1461 VCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ------CYCKTNVRGQACDTCKEE 1514
C+ C PG+ P C CD+ + C CK NV G+ C+ C +
Sbjct: 850 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Query: 1515 YFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVP 1574
F+L NPDGC KCFC G + C+SS ++ A + + P + N H
Sbjct: 910 SFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASE-EPGHFSLTNAAS--THTTNE 966
Query: 1575 ELTNVTVLTVGLNDGVTNGKVAYF-GAPEYYLGKRLTSYGGYLTYTVHYTTR-GDGDAVA 1632
+ + T +G + YF P +LG ++TSYGG L +TV ++ G
Sbjct: 967 GIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHG 1026
Query: 1633 APDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISG 1692
P V++ G N L H+ ++P G P T V E+ + DG P TR+ + AL I
Sbjct: 1027 QPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDT 1086
Query: 1693 LYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAE 1752
L IRASY + E+ +S + +++ V G + A VE+C CP YRG SC+ C
Sbjct: 1087 LLIRASYAQQPAESRVSGISMDVAVPEETGQD----PALEVEQCSCPPGYRGPSCQDCDT 1142
Query: 1753 GHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGT 1808
G+ R PSG C C C+GHS+ C+ TG C C +T G CE C GY+GDA GT
Sbjct: 1143 GYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGT 1202
Query: 1809 PRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDL 1868
P+DC +C C + A +C L +G C PG+ G CE CA GYYG P
Sbjct: 1203 PQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQP 1262
Query: 1869 HTGDYCKPCNCSGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCAP-GFYGDAIFSK 1925
D P N +PQ S CD+ G C +C G C+ C P F+ A
Sbjct: 1263 CQRDSQVPGPIGCNCDPQGSVSSQCDAA-GQC-QCKAQVEGLTCSHCRPHHFHLSASNPD 1320
Query: 1926 NCTACIC 1932
C C C
Sbjct: 1321 GCLPCFC 1327
Score = 217 bits (530), Expect = 6e-55
Identities = 141/434 (32%), Positives = 194/434 (44%), Gaps = 24/434 (5%)
Query: 1511 CKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI----DEMVDWYPVDVLINNTIE 1566
C + +F L+ + C CFCFG T+ C S+ I D+ D+ V+V +
Sbjct: 505 CPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPG 562
Query: 1567 LYPHEDVPELTNVTVLTVGLNDGVTNGKV--AYFGAPEYYLGKRLTSYGGYLTYTVHYT- 1623
P + ++ L D V +++ PE +LG ++ SYGG L Y V Y
Sbjct: 563 TPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYEL 622
Query: 1624 TRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQF 1683
RG + V PDV++ G L+ G V+ SEE + G PV R +
Sbjct: 623 ARGMLEPVQRPDVVLVGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPVQRAEL 682
Query: 1684 MHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYR 1743
+ L ++ + I+ Y LS++ ++ V + RA SVEEC+CP Y
Sbjct: 683 LQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHG----RAHSVEECRCPIGYS 738
Query: 1744 GLSCEQCAEGHYRLPSG----FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSG 1799
GLSCE C R+P G C C CNGH+ CD G CLNC NT G C C +G
Sbjct: 739 GLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAG 798
Query: 1800 YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGY 1859
+ GDA T C C CP S F+ +C L +G C PGY G RCE CA GY
Sbjct: 799 FFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY 858
Query: 1860 YGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG-FY 1918
G P + G C+P N + + GS + +G+ +C NN G CN CA G F+
Sbjct: 859 EGNP----IQPGGKCRPVN-QEIVRCDERGSMGT-SGEACRCKNNVVGRLCNECADGSFH 912
Query: 1919 GDAIFSKNCTACIC 1932
C C C
Sbjct: 913 LSTRNPDGCLKCFC 926
Score = 118 bits (283), Expect = 5e-25
Identities = 71/208 (34%), Positives = 95/208 (45%), Gaps = 26/208 (12%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S+ C C GY G CE C A + +P L T C C+C+G+ + SCD + G
Sbjct: 727 SVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGT---CSGCSCNGHAS-----SCDPVYG 778
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTT--------GT 1946
CL C +NT G CN C GF+GDA+ + +C C C + S T T
Sbjct: 779 HCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 838
Query: 1947 C-VCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIA--SESTQCDDDNGQCRCAKGV 2001
C C PG G +C+ CAP + G + G C P N I E CRC V
Sbjct: 839 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNV 898
Query: 2002 TGKQCDQCAAGFWNYT---KDGCDHCNC 2026
G+ C++CA G ++ + DGC C C
Sbjct: 899 VGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 111 bits (268), Expect = 3e-23
Identities = 67/202 (33%), Positives = 88/202 (43%), Gaps = 32/202 (15%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C+C Y G +C C GY P TC+ C+C C+ +G C C+
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHS---EACEPETGACQGCQHHT 1182
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNC--DPT-GSTSTSC--SADGK--CN-CLTNFG 573
GPRC+QC GYY G + C C C DP G + +C DG C+ C
Sbjct: 1183 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 574 GAQCDQCSPGYYKYPD----C---------LSCNCDVSGSIGSTCDDNGLCHCKSNFDGA 620
G C++C+PGYY P C + CNCD GS+ S CD G C CK+ +G
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 1302
Query: 621 KCDTCREQFYNYPACEECNCDP 642
C CR ++ A C P
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLP 1324
Score = 102 bits (245), Expect = 2e-20
Identities = 72/226 (31%), Positives = 103/226 (45%), Gaps = 41/226 (18%)
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTST 558
+ +G +P++ +V QC C G+ GP C C +GY G C C+C S
Sbjct: 1113 EETGQDPAL--EVE-QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSE 1166
Query: 559 SCSAD-GKCN-CLTNFGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC-- 605
+C + G C C + G +C+QC PGYY DC C C +G TC
Sbjct: 1167 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFL 1226
Query: 606 --DDNGLCH-CKSNFDGAKCDTCREQFYNYPA----CEE---------CNCDPRGVTASF 649
D + C C G C+ C +Y P+ C+ CNCDP+G +S
Sbjct: 1227 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS- 1285
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C + AG+ CQCK +V+G C+ C+P +++L NP GC C C
Sbjct: 1286 -QCDA--AGQ-CQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 101 bits (242), Expect = 5e-20
Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 38/210 (18%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLCP-C 427
E +C C P ++ P C C GY P+ C+ C+C+ E C P G C C
Sbjct: 1122 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGC 1178
Query: 428 KYNYAGKSCEICEDGYYS-------PECKNCEC---NTVGSVSYVCDKLT-GDCTCKS-- 474
+++ G CE C+ GYY +C+ C C G ++ C T G TC +
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 475 -KYSGRTCNQCQAGYYNYPT----CK---------PCNCDTSGTEPSICDDVSGQCICKA 520
+SGR C +C GYY P+ C+ CNCD G+ S C D +GQC CKA
Sbjct: 1239 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAAGQCQCKA 1297
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
G C C ++ C+PC C
Sbjct: 1298 QVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 92.7 bits (220), Expect = 2e-17
Identities = 61/202 (30%), Positives = 88/202 (43%), Gaps = 26/202 (12%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKC-NCLTN 571
+C C G+ G C+ C ++ +V G C C+C+ G S+ G C NC N
Sbjct: 730 ECRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCSCN--GHASSCDPVYGHCLNCQHN 786
Query: 572 FGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC----DDNGLCH-CKSNF 617
G QC++C G++ C C C D S TC D C C +
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 618 DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC---GSV-PAGELCQCKDRVQGRICN 673
G +C++C + P C P V C GS+ +GE C+CK+ V GR+CN
Sbjct: 847 TGRRCESCAPGYEGNPIQPGGKCRP--VNQEIVRCDERGSMGTSGEACRCKNNVVGRLCN 904
Query: 674 DCKPLYWNLQEYNPFGCEQCNC 695
+C ++L NP GC +C C
Sbjct: 905 ECADGSFHLSTRNPDGCLKCFC 926
Score = 87.0 bits (206), Expect = 1e-15
Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C PGY G C+ CA GY + L+ G +C+ C C+G+ + C G C +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGY--TRTGSGLYLG-HCELCECNGHSD-----LCHPETGACSQ 1581
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFS--KNCTACIC-----DEFGMADCDSTTG---TC-VC 1949
C +N AG C LCAPG+YGDA ++C C C + C+S C C
Sbjct: 1582 CQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTAC 1641
Query: 1950 RPGVIGEKCDRCAPDHWG 1967
PG G+ C++C P + G
Sbjct: 1642 EPGYTGQYCEQCGPGYVG 1659
Score = 86.2 bits (204), Expect = 2e-15
Identities = 65/222 (29%), Positives = 93/222 (41%), Gaps = 38/222 (17%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCE-CRPEF 385
+C G +C C Y R + L C+ C C H CE E+G C+ C+
Sbjct: 1127 SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGHSEA--CEPETGACQGCQHHT 1182
Query: 386 QPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE--H-C-TPTDG--LCP-CKYNYA 432
+ P C C GY+ +C+ C C + G+ H C TDG C C ++
Sbjct: 1183 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 433 GKSCEICEDGYY-SPE----CKN---------CECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G+ CE C GYY +P C+ C C+ GSVS CD G C CK++ G
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEG 1301
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
TC+ C+ +++ P C P C ++ QC A
Sbjct: 1302 LTCSHCRPHHFHLSASNPDGC-----LPCFCMGITQQCASSA 1338
Score = 85.0 bits (201), Expect = 5e-15
Identities = 60/215 (27%), Positives = 91/215 (42%), Gaps = 29/215 (13%)
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDS 1942
P++ G ++ + C G +C C G+ ++ C C C A C+
Sbjct: 1112 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA-CEP 1170
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC------GIASESTQCDDD- 1991
TG C C+ G +C++C P ++G T C C C G A+ + D D
Sbjct: 1171 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDG 1230
Query: 1992 NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---------CNCNTGYSVGFMCNAT 2039
+ C C+ G +G+ C++CA G++ G C CNC+ SV C+A
Sbjct: 1231 HPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA 1290
Query: 2040 GQCECLPGVIGEKCDRC-PERWVLIPQ--EGCLEC 2071
GQC+C V G C C P + L +GCL C
Sbjct: 1291 GQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 1325
Score = 83.0 bits (196), Expect = 2e-14
Identities = 58/205 (28%), Positives = 86/205 (41%), Gaps = 26/205 (12%)
Query: 316 NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE 375
+GR +C C G++C C + R G + L C C C+ H S+ C+
Sbjct: 722 HGRAHSVEEC-RCPIGYSGLSCESCDAHFTRVPGGPY--LGTCSGCSCNGHASS--CDPV 776
Query: 376 SGRC-ECRPEFQPPDCSSCAYGYFD------YPNCKPCTC---NLNGTEGEHC-TPTDGL 424
G C C+ + P C+ C G+F +C+PC C + + + C TDG
Sbjct: 777 YGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQ 836
Query: 425 CPCKY---NYAGKSCEICEDGYY-SPECKNCECNTVGSVSYVCDK-----LTGD-CTCKS 474
C Y G+ CE C GY +P +C V CD+ +G+ C CK+
Sbjct: 837 ATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKN 896
Query: 475 KYSGRTCNQCQAGYYNYPTCKPCNC 499
GR CN+C G ++ T P C
Sbjct: 897 NVVGRLCNECADGSFHLSTRNPDGC 921
Score = 82.6 bits (195), Expect = 2e-14
Identities = 67/235 (28%), Positives = 91/235 (38%), Gaps = 42/235 (17%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC G C C + F R+ +C C+C+ H + C DP
Sbjct: 731 CRCPIGYSGLSCESCDAHFT----RVPGGPYLGTCSGCSCNGHASSC--DPVY------- 777
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC-----DPHFS 368
G CLNCQHNTEG CNKC+ ++ K C+PC C FS
Sbjct: 778 ---------GHCLNCQHNTEGPQCNKCKAGFFGDAMKA--TATSCRPCPCPYIDASRRFS 826
Query: 369 TGNCEEESGR--CE-CRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHCTP 420
+ G+ C+ C P + C SCA GY P C+P + +
Sbjct: 827 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMG 886
Query: 421 TDG-LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKS 474
T G C CK N G+ C C DG + +N + G + C ++ CT S
Sbjct: 887 TSGEACRCKNNVVGRLCNECADGSFHLSTRNPD----GCLKCFCMGVSRHCTSSS 937
Score = 79.8 bits (188), Expect = 2e-13
Identities = 55/202 (27%), Positives = 83/202 (41%), Gaps = 23/202 (11%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD------CLSCNCDVSGSIGSTCDD-NGLC-HCKSN 616
+C C + G C+ C + + P C C+C+ S+CD G C +C+ N
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCN---GHASSCDPVYGHCLNCQHN 786
Query: 617 FDGAKCDTCREQFYN------YPACEECNCDPRGVTASFAG-CGSVPAGEL-CQ-CKDRV 667
+G +C+ C+ F+ +C C C + F+ C G+ C C
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 668 QGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
GR C C P Y P G C N + + G+ T C CK +V R C+
Sbjct: 847 TGRRCESCAPGYEG-NPIQPGGKCRPVNQEIV-RCDERGSMGTSGEACRCKNNVVGRLCN 904
Query: 727 QCLDGFYRLQTNDVFGCTECDC 748
+C DG + L T + GC +C C
Sbjct: 905 ECADGSFHLSTRNPDGCLKCFC 926
Score = 78.2 bits (184), Expect = 5e-13
Identities = 69/248 (27%), Positives = 94/248 (37%), Gaps = 52/248 (20%)
Query: 244 DPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYD 303
DPA L + C C GP C C +G+ R +CE C+CH H+ C +
Sbjct: 1118 DPA--LEVEQCSCPPGYRGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--E 1169
Query: 304 PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC 363
PE G C CQH+TEG C +C+P YY +R D CQ C C
Sbjct: 1170 PET----------------GACQGCQHHTEGPRCEQCQPGYYGD-AQRGTPQD-CQLCPC 1211
Query: 364 --DPHF--STGNC---EEESGRCE-CRPEFQPPDCSSCAYGYFDYPN----CK------- 404
DP + C + C+ C P C CA GY+ P+ C+
Sbjct: 1212 YGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 1271
Query: 405 --PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
C C+ G+ C G C CK G +C C ++ N + G +
Sbjct: 1272 PIGCNCDPQGSVSSQCDAA-GQCQCKAQVEGLTCSHCRPHHFHLSASNPD----GCLPCF 1326
Query: 463 CDKLTGDC 470
C +T C
Sbjct: 1327 CMGITQQC 1334
Score = 77.4 bits (182), Expect = 9e-13
Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 1158 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 1206
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + + ++ +G C C G +C +C P YY P
Sbjct: 1207 QLCPCYG-------DPAAGQAAHTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNP 1257
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----- 398
+ + D P C CDP S + + +G+C+C+ + + CS C +F
Sbjct: 1258 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSAS 1317
Query: 399 DYPNCKPCTC 408
+ C PC C
Sbjct: 1318 NPDGCLPCFC 1327
Score = 74.9 bits (176), Expect = 5e-12
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPDCL---SCN-CDVSGSIGSTCDDNGLCH-CKSNFDG 619
+C+C + G C C GY + P L +C C G + + G C C+ + +G
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 620 AKCDTCREQFYNYPA------CEECNC--DPRGVTASFAGCGSVPAGELCQ-CKDRVQGR 670
+C+ C+ +Y C+ C C DP A+ C C GR
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1244
Query: 671 ICNDCKPLYW-NLQEYNPF-------GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C C P Y+ N + P G CNC+ G+++S C+ +GQC CK V
Sbjct: 1245 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS--QCDA-AGQCQCKAQVEG 1301
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDC 748
C C + L ++ GC C C
Sbjct: 1302 LTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 73.7 bits (173), Expect = 1e-11
Identities = 48/146 (32%), Positives = 64/146 (43%), Gaps = 24/146 (16%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGY------FDYPNCKPCTCNLNGTEGEHCTPTDGLCP-C 427
E C C P + C CA GY +C+ C CN + C P G C C
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQC 1582
Query: 428 KYNYAGKSCEICEDGYY------SPE-CKNCEC---NTVGSVSYVCDKLTGD---CT-CK 473
++N AG+ CE+C GYY +PE C+ C C N S C+ L CT C+
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACE 1642
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNC 499
Y+G+ C QC GY P+ + C
Sbjct: 1643 PGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/196 (27%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQ-C 663
C C + G C C + P+ CE C+C P CQ C
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE-------PETGACQGC 1178
Query: 664 KDRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCN---LAGTLNSLGACNTKSGQ-C-VCK 717
+ +G C C+P Y+ + Q P C+ C C AG +T C C
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 718 QHVGERQCDQCLDGFYR--------LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHS 769
R C++C G+Y + + V G C+CD GS+ + CD GQC C +
Sbjct: 1239 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKA 1297
Query: 770 RVEGRRCDQPIRAHYF 785
+VEG C R H+F
Sbjct: 1298 QVEGLTCSH-CRPHHF 1312
Score = 70.9 bits (166), Expect = 8e-11
Identities = 62/197 (31%), Positives = 74/197 (37%), Gaps = 34/197 (17%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGHA +C+P G+ CQHNT GPQCNKC +GF + + SC P
Sbjct: 764 CSCNGHASSCDPV--YGHC----LNCQHNTEGPQCNKCKAGFFGDAMKATAT----SCRP 813
Query: 291 CNCHNHTTECTYDPEID-EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C P ID +R S +G C C G C C P Y G
Sbjct: 814 CPC----------PYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY---EG 860
Query: 350 KRWDELDVCQP-----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
C+P +CD S G E C C+ C+ CA G F
Sbjct: 861 NPIQPGGKCRPVNQEIVRCDERGSMGTSGE---ACRCKNNVVGRLCNECADGSFHLSTRN 917
Query: 405 PCTCNLNGTEG--EHCT 419
P C G HCT
Sbjct: 918 PDGCLKCFCMGVSRHCT 934
Score = 70.5 bits (165), Expect = 1e-10
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 24/144 (16%)
Query: 425 CPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDCT-CKSKY 476
C C Y G SC+ C GY Y C+ CECN S +C TG C+ C+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQCQHNA 1586
Query: 477 SGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSI---CDDVSG---QCI-CKAGFG 523
+G C C GYY T C+PC C + E C+ + +C C+ G+
Sbjct: 1587 AGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYT 1646
Query: 524 GPRCDQCLSGYYMQVLGRERQCVP 547
G C+QC GY + QC+P
Sbjct: 1647 GQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 68.5 bits (160), Expect = 4e-10
Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 30/210 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C C + C SC + P C C+CN + + C P G C C++N
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASS---CDPVYGHCLNCQHNT 787
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKL----TGDCTCKS---KYS 477
G C C+ G++ + C+ C C + + D G TC + Y+
Sbjct: 788 EGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYT 847
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD-----VSGQ-CICKAGFGGPRCDQCL 531
GR C C GY P C E CD+ SG+ C CK G C++C
Sbjct: 848 GRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECA 907
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
G + C+ C C TS S
Sbjct: 908 DGSFHLSTRNPDGCLKCFCMGVSRHCTSSS 937
Score = 66.9 bits (156), Expect = 1e-09
Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 19/143 (13%)
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
+C C Y G +C C GY + C+ C C+ +C +G C C+
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHS---DLCHPETGACSQCQHN 1585
Query: 522 FGGPRCDQCLSGYYMQVL-GRERQCVPCNC---DPTGSTSTSCSADG----KCN-CLTNF 572
G C+ C GYY G C PC C +P S +C + G +C C +
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 573 GGAQCDQCSPGYYKYPDCLSCNC 595
G C+QC PGY P C
Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 65.3 bits (152), Expect = 4e-09
Identities = 53/197 (26%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 1900 KCVNNTAGAACNLCAPGF--YGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGE 1956
+C +G +C C F + C+ C C+ + CD G C+ C+ G
Sbjct: 732 RCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHA-SSCDPVYGHCLNCQHNTEGP 790
Query: 1957 KCDRCAPDHWG---LNTGLGCTPCNCGIASESTQCDDD-----NGQCRC---AKGVTGKQ 2005
+C++C +G T C PC C S + D +GQ C A G TG++
Sbjct: 791 QCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRR 850
Query: 2006 CDQCAAGF-WNYTKDG--CDHCN-----CNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
C+ CA G+ N + G C N C+ S+G A C C V+G C+ C
Sbjct: 851 CESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEA---CRCKNNVVGRLCNECA 907
Query: 2058 ERWVLIP---QEGCLEC 2071
+ + +GCL+C
Sbjct: 908 DGSFHLSTRNPDGCLKC 924
Score = 62.9 bits (146), Expect = 2e-08
Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN-CGIASESTQCDDDNGQC-RCAKGVTGK 2004
C C PG IG C CAP + +GL C C S C + G C +C G+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGE 1589
Query: 2005 QCDQCAAGFWN----YTKDGCDHCNC---NTGYSVGFMCNATG----QC-ECLPGVIGEK 2052
C+ CA G++ T + C C C N C + G +C C PG G+
Sbjct: 1590 FCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQY 1649
Query: 2053 CDRCPERWV 2061
C++C +V
Sbjct: 1650 CEQCGPGYV 1658
Score = 61.7 bits (143), Expect = 5e-08
Identities = 50/175 (28%), Positives = 72/175 (41%), Gaps = 31/175 (17%)
Query: 1340 CLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYG------FPNCRPCHCP--- 1389
C C+ S+ C+ G C C+ N G C+ C+ G++G +CRPC CP
Sbjct: 764 CSCNGHASS---CDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYID 820
Query: 1390 ------STAICDDNGMC---ICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGN 1440
T D +G C G C+ C P +Q G N V +
Sbjct: 821 ASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCD 880
Query: 1441 QLQCEADSGK-CACRENVRGRVCDHCVPGHYAF----PD-CYQCTC---NRHGTT 1486
+ SG+ C C+ NV GR+C+ C G + PD C +C C +RH T+
Sbjct: 881 ERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTS 935
Score = 61.3 bits (142), Expect = 6e-08
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 16/140 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC-ECRPEFQ 386
C G++C C P Y R + L C+ C+C+ H + C E+G C +C+
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLY--LGHCELCECNGH--SDLCHPETGACSQCQHNAA 1587
Query: 387 PPDCSSCAYGYF------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C CA GY+ +C+PC C L E + L G C CE
Sbjct: 1588 GEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESL-----GAGGYRCTACE 1642
Query: 441 DGYYSPECKNCECNTVGSVS 460
GY C+ C VG+ S
Sbjct: 1643 PGYTGQYCEQCGPGYVGNPS 1662
Score = 58.0 bits (134), Expect = 6e-07
Identities = 49/175 (28%), Positives = 61/175 (34%), Gaps = 32/175 (18%)
Query: 242 PADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECT 301
P++ L + CRC G C C G+ R CE C C+ H+ C
Sbjct: 1518 PSNRPRALEVEECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLC- 1572
Query: 302 YDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
PE G C CQHN G C C P YY E CQPC
Sbjct: 1573 -HPET----------------GACSQCQHNAAGEFCELCAPGYYGDATAGTPE--DCQPC 1613
Query: 362 QC---DP-HFSTGNCEEESG---RC-ECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
C +P + + CE RC C P + C C GY P+ + C
Sbjct: 1614 ACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 56.4 bits (130), Expect = 2e-06
Identities = 51/180 (28%), Positives = 84/180 (46%), Gaps = 19/180 (10%)
Query: 3022 SFNGTDSYLRFVDVTSENPQLTL--KFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGK 3079
S +G SYL +T+ + +L L +FK P+G+L S ++ + D +SL++V G
Sbjct: 3931 SLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLF--SGGKSGPVEDFVSLAMVGGH 3988
Query: 3080 LVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDG-- 3137
L R +L +GL ++ L H SA +L D + P L G
Sbjct: 3989 LEF---RYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGS--LRVNGGRPVLRSSPGKS 4043
Query: 3138 -------VLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
+L++GGV+P +S + F GC+G+ ++NG+ L+L F S G+C
Sbjct: 4044 QGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL-GSQGIGQC 4102
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 19/141 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTA-ICD-DNGMCI-CPKNVEG 1408
+C C P IG +C C GY +C C C + +C + G C C N G
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAG 1588
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNC---NPLGVVGNQLQCEADSG-KC-ACRENVRG 1459
E C+ C P + D G C C C NP + + G +C AC G
Sbjct: 1589 EFCELCAPGYYG-DATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTG 1647
Query: 1460 RVCDHCVPGHYAFPDCYQCTC 1480
+ C+ C PG+ P C
Sbjct: 1648 QYCEQCGPGYVGNPSVQGGQC 1668
Score = 51.2 bits (117), Expect = 7e-05
Identities = 41/182 (22%), Positives = 65/182 (35%), Gaps = 21/182 (11%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C++C F P C C+C+ + C V G C+
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHA-----SSCDPV-YGHCLNCQ 784
Query: 665 DRVQGRICNDCKP-LYWNLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKS-GQCVCKQ--- 718
+G CN CK + + + C C C C + GQ C
Sbjct: 785 HNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 844
Query: 719 -HVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ-CHCHSRVEGRRC 776
+ G R+C+ C G+ C + +I + T+G+ C C + V GR C
Sbjct: 845 GYTG-RRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 903
Query: 777 DQ 778
++
Sbjct: 904 NE 905
Score = 49.2 bits (112), Expect = 3e-04
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 19/114 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH+D C P A +CQHN G C C G+ + + C+P
Sbjct: 1563 CECNGHSDLCHPETGA------CSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQP 1612
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C C +P E S GG +C C+ G C +C P Y
Sbjct: 1613 CACP------LTNP---ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGY 1657
Score = 48.0 bits (109), Expect = 6e-04
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK
Sbjct: 1247 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQ 1298
Query: 1365 VIGRTCSACRTGYYGF-----PNCRPCHC 1388
V G TCS CR ++ C PC C
Sbjct: 1299 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 47.6 bits (108), Expect = 8e-04
Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 21/106 (19%)
Query: 1341 LCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF------PNCRPCHCPST-- 1391
LC+ G ++L C+ G C C+ N G C C GYYG +C+PC CP T
Sbjct: 1562 LCECNGHSDL-CHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNP 1620
Query: 1392 -----AICDDNG----MC-ICPKNVEGENCDRCKP-YTFNFDVQRG 1426
C+ G C C G+ C++C P Y N VQ G
Sbjct: 1621 ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGG 1666
Score = 47.2 bits (107), Expect = 0.001
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 14/138 (10%)
Query: 3516 SISMEVRPRNTTGLLL-------SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSN 3568
+I +EVR +GLLL KD++ L L D +V + G+G R L +
Sbjct: 4229 TIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEAR----LVS 4284
Query: 3569 KHYLCDGNWHKIHXXXXXXXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKV 3626
+ + DG WH++ DG S G + + ++YIGG + +
Sbjct: 4285 EDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAP-DVATL 4343
Query: 3627 RGVHSRRGFTGCVRNIVV 3644
G G TGCV+N+V+
Sbjct: 4344 TGGRFSSGITGCVKNLVL 4361
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 2890 GEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD- 2948
G+G F SL +QDG + + LG+ E ++ + NDG+WH++ A R + S+ VD
Sbjct: 4254 GQGKDFISLGLQDGHLVFRYQLGSGEARLV--SEDPINDGEWHRVTALREGRRGSIQVDG 4311
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDR---GFDGCMRQISIN 2996
E++ S P+ + + ++ GG R G GC++ + ++
Sbjct: 4312 EELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4362
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 2877 FRTYAPNG-LIYLVGEGGY---FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWH 2932
F+ AP+G L++ G+ G F SL M G + + LG+ L ++ + G+WH
Sbjct: 3957 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGS--GLAVLRSAEPLALGRWH 4014
Query: 2933 KLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNF-GGNNKGILQVPDRG----FD 2987
++ A R SL V+ S+ + +L T+ + GG + P F
Sbjct: 4015 RVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFR 4074
Query: 2988 GCMRQISINGVNLDLSENL---ESIGMAY 3013
GC+ ++S+NG LDL+ + + IG Y
Sbjct: 4075 GCVGEVSVNGKRLDLTYSFLGSQGIGQCY 4103
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 3361 FLAFFMRDAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVD-SEMVGET 3419
F++ ++D L + + G + S ND +WH VT R G G + VD E+V
Sbjct: 4259 FISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGR 4318
Query: 3420 SVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMN 3466
S N ++ Y GG V + F GC+K L+++
Sbjct: 4319 SPGPNVAVNAKGSVYIGGAPDV---ATLTGGRFSSGITGCVKNLVLH 4362
Score = 43.2 bits (97), Expect = 0.018
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 8/95 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQC-VC 716
E C+C G C DC P Y G CE C CN L C+ ++G C C
Sbjct: 1528 EECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL-----CHPETGACSQC 1582
Query: 717 KQHVGERQCDQCLDGFYRLQT-NDVFGCTECDCDI 750
+ + C+ C G+Y T C C C +
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPL 1617
Score = 42.7 bits (96), Expect = 0.024
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 15/72 (20%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKDG-------CDHCNCNTGYSVGFMCN-ATGQC-EC 2044
+CRC G G C CA G YT+ G C+ C CN G+S +C+ TG C +C
Sbjct: 1529 ECRCPPGYIGLSCQDCAPG---YTRTGSGLYLGHCELCECN-GHS--DLCHPETGACSQC 1582
Query: 2045 LPGVIGEKCDRC 2056
GE C+ C
Sbjct: 1583 QHNAAGEFCELC 1594
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 16/195 (8%)
Query: 3478 NALRCVDNIEDGVYFEA-SNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGK 3536
+ LRC E+GV S + +YL L E+ + +E +P G+LL GK
Sbjct: 3917 SGLRC----EEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGK 3972
Query: 3537 ----KDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXX 3592
+D++ L ++ + E G+G L + L G WH++
Sbjct: 3973 SGPVEDFVSLAMVGGHLEFRYELGSG----LAVLRSAEPLALGRWHRVSAERLNKDGSLR 4028
Query: 3593 XDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVK 3650
+G + G + H+ LY+GG E + + F GCV + V +
Sbjct: 4029 VNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLD 4088
Query: 3651 VPNSAVGRGAHVGVC 3665
+ S +G +G C
Sbjct: 4089 LTYSFLG-SQGIGQC 4102
Score = 39.1 bits (87), Expect = 0.30
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 21/147 (14%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT G +L+ G G + D++ +G+Q+G+ +G AR+ +
Sbjct: 4235 RTSTASGLLLWQGVEVG---EAGQGKDFISLGLQDGHLVFRYQLGSGE------ARLVSE 4285
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
+ D W++V R GRR + + +G + + + PG + N K +Y+
Sbjct: 4286 DPINDGEWHRVTALREGRRGSIQV-----DGEELVSGRS---PGPNVAVN---AKGSVYI 4334
Query: 2790 GGVPSDAKLQGISFPA-FEGQIEELMI 2815
GG P A L G F + G ++ L++
Sbjct: 4335 GGAPDVATLTGGRFSSGITGCVKNLVL 4361
Score = 38.7 bits (86), Expect = 0.39
Identities = 30/134 (22%), Positives = 45/134 (33%), Gaps = 18/134 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C C + + CE C C+ + G QC+
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN------GHSDLCHPETGACSQCQ 1583
Query: 665 DRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKSG---QC-VCKQ 718
G C C P Y+ + P C+ C C L N C + +C C+
Sbjct: 1584 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1643
Query: 719 HVGERQCDQCLDGF 732
+ C+QC G+
Sbjct: 1644 GYTGQYCEQCGPGY 1657
Score = 37.5 bits (83), Expect = 0.90
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 1932 CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
C G D +S++ CVC G G +C+ + L C P CG + D
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEH--------SQALHCHPEACGPDATCVNRPD 3904
Query: 1991 DNG-QCRCAKGVTGKQCDQ 2008
G CRC G +G +C++
Sbjct: 3905 GRGYTCRCHLGRSGLRCEE 3923
Score = 37.1 bits (82), Expect = 1.2
Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 9/118 (7%)
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQCRCAKGVTGKQCDQCAA 2011
V G D P+ G + L C+C C D D G R G+ C++C+
Sbjct: 1102 VSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSC 1161
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATG-QCE-CLPGVIGEKCDRCPERWVLIPQEG 2067
+ C TG G + G +CE C PG G+ P+ L P G
Sbjct: 1162 ------HGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG 1213
Score = 37.1 bits (82), Expect = 1.2
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 13/83 (15%)
Query: 1737 QCPRAYRGLSCEQCAEGHYR-LPSGF---CVPCQC------NGHSDQCD-VNTG--ICLN 1783
QC G CE CA G+Y +G C PC C N S C+ + G C
Sbjct: 1581 QCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTA 1640
Query: 1784 CADNTIGDHCEFCMSGYHGDATV 1806
C G +CE C GY G+ +V
Sbjct: 1641 CEPGYTGQYCEQCGPGYVGNPSV 1663
Score = 36.3 bits (80), Expect = 2.1
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 12/94 (12%)
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCV 546
G + PTC+ C G + + S C+C AGF G RC+ + Q L C
Sbjct: 3841 GISHCPTCRDRPCQNGG-QCHDSESSSYVCVCPAGFTGSRCE------HSQAL----HCH 3889
Query: 547 PCNCDPTGSTSTSCSADG-KCNCLTNFGGAQCDQ 579
P C P + G C C G +C++
Sbjct: 3890 PEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEE 3923
Score = 34.7 bits (76), Expect = 6.4
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 15/130 (11%)
Query: 1269 TSKGVWLDYVLVIEASDFTDAVLTEANILDYTR-----EFIEQCASYNYYISPNETGL-C 1322
T G++L + + E + +D E + EF E CA Y + T C
Sbjct: 1551 TGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDC 1610
Query: 1323 REAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPN 1382
+ +T+ N +R C + +G+ C C+P G+ C C GY G P+
Sbjct: 1611 QPCACPLTNPENMFSRTC--ESLGAGGYRCTA------CEPGYTGQYCEQCGPGYVGNPS 1662
Query: 1383 CRPCHC-PST 1391
+ C P T
Sbjct: 1663 VQGGQCLPET 1672
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 319 bits (784), Expect = 1e-85
Identities = 197/549 (35%), Positives = 255/549 (46%), Gaps = 55/549 (10%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPS-TAICD-DNGMCI-CPKNVEG 1408
QC C P G +C C TGY P+ C C C + C+ + G C C + EG
Sbjct: 1104 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1163
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQLQ-CEADSG---KC-ACRENVRG 1459
C++C+P + D QRG C C C G C D+ C AC G
Sbjct: 1164 PRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSG 1222
Query: 1460 RVCDHCVPGHYAFPD----CYQ---------CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
R C+ C PG+Y P C + C C+ G+ CD QC CK V G
Sbjct: 1223 RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGL 1281
Query: 1507 ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVD----VLIN 1562
C C+ +F+L NPDGC CFC G T +C+SS YT I + P D L+N
Sbjct: 1282 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLIS--THFAPGDFQGFALVN 1339
Query: 1563 --NTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTV 1620
L V + L+ G N + Y+ PE Y G ++ +YGG L YT+
Sbjct: 1340 PQRNSRLTGEFTVEPVPEGAQLSFG-NFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTL 1398
Query: 1621 HYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMP--WTHSVKLSEEEFSTLDGAPV 1678
YT G ++ PDV I G N LV QP + P ++ + EE + DG P
Sbjct: 1399 SYTAGPQGSPLSDPDVQITGNNIMLV---ASQPALQGPERRSYEIMFREEFWRRPDGQPA 1455
Query: 1679 TRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQC 1738
TR+ + AL ++ L IRA++ + S+S V LE+ RA VEEC+C
Sbjct: 1456 TREHLLMALADLDELLIRATFSSVPLVASISAVSLEVAQPGPSNRP----RALEVEECRC 1511
Query: 1739 PRAYRGLSCEQCAEGHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
P Y GLSC+ CA G+ R SG C C+CNGHSD C TG C C N G+ CE
Sbjct: 1512 PPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCE 1571
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
C GY+GDAT GTP DC CACP+ P N F+ +C+ G C+PGY G CE
Sbjct: 1572 LCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQ 1631
Query: 1855 CAAGYYGIP 1863
C GY G P
Sbjct: 1632 CGPGYVGNP 1640
Score = 301 bits (739), Expect = 3e-80
Identities = 194/607 (31%), Positives = 267/607 (43%), Gaps = 41/607 (6%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPSTAI-CDD-NGMCI-CPKNVEG 1408
+C C G +C +C + P C C C A CD G C+ C N EG
Sbjct: 709 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDPVYGHCLNCQHNTEG 768
Query: 1409 ENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ----CEADS---GKC-ACRENVRGR 1460
C++CK F ++ C P + + C D+ C AC GR
Sbjct: 769 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGR 828
Query: 1461 VCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ------CYCKTNVRGQACDTCKEE 1514
C+ C PG+ P C CD+ + C CK NV G+ C+ C +
Sbjct: 829 RCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 888
Query: 1515 YFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNTIELYPHEDVP 1574
F+L NPDGC KCFC G + C+SS ++ A + + P + N H
Sbjct: 889 SFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASE-EPGHFSLTNAAS--THTTNE 945
Query: 1575 ELTNVTVLTVGLNDGVTNGKVAYF-GAPEYYLGKRLTSYGGYLTYTVHYTTR-GDGDAVA 1632
+ + T +G + YF P +LG ++TSYGG L +TV ++ G
Sbjct: 946 GIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHG 1005
Query: 1633 APDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISG 1692
P V++ G N L H+ ++P G P T V E+ + DG P TR+ + AL I
Sbjct: 1006 QPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDT 1065
Query: 1693 LYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAE 1752
L IRASY + E+ +S + +++ V G + A VE+C CP YRG SC+ C
Sbjct: 1066 LLIRASYAQQPAESRVSGISMDVAVPEETGQD----PALEVEQCSCPPGYRGPSCQDCDT 1121
Query: 1753 GHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGT 1808
G+ R PSG C C C+GHS+ C+ TG C C +T G CE C GY+GDA GT
Sbjct: 1122 GYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGT 1181
Query: 1809 PRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDL 1868
P+DC +C C + A +C L +G C PG+ G CE CA GYYG P
Sbjct: 1182 PQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQP 1241
Query: 1869 HTGDYCKPCNCSGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCAP-GFYGDAIFSK 1925
D P N +PQ S CD+ G C +C G C+ C P F+ A
Sbjct: 1242 CQRDSQVPGPIGCNCDPQGSVSSQCDAA-GQC-QCKAQVEGLTCSHCRPHHFHLSASNPD 1299
Query: 1926 NCTACIC 1932
C C C
Sbjct: 1300 GCLPCFC 1306
Score = 217 bits (530), Expect = 6e-55
Identities = 141/434 (32%), Positives = 194/434 (44%), Gaps = 24/434 (5%)
Query: 1511 CKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI----DEMVDWYPVDVLINNTIE 1566
C + +F L+ + C CFCFG T+ C S+ I D+ D+ V+V +
Sbjct: 484 CPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPG 541
Query: 1567 LYPHEDVPELTNVTVLTVGLNDGVTNGKV--AYFGAPEYYLGKRLTSYGGYLTYTVHYT- 1623
P + ++ L D V +++ PE +LG ++ SYGG L Y V Y
Sbjct: 542 TPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYEL 601
Query: 1624 TRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQF 1683
RG + V PDV++ G L+ G V+ SEE + G PV R +
Sbjct: 602 ARGMLEPVQRPDVVLVGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPVQRAEL 661
Query: 1684 MHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYR 1743
+ L ++ + I+ Y LS++ ++ V + RA SVEEC+CP Y
Sbjct: 662 LQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHG----RAHSVEECRCPIGYS 717
Query: 1744 GLSCEQCAEGHYRLPSG----FCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSG 1799
GLSCE C R+P G C C CNGH+ CD G CLNC NT G C C +G
Sbjct: 718 GLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAG 777
Query: 1800 YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGY 1859
+ GDA T C C CP S F+ +C L +G C PGY G RCE CA GY
Sbjct: 778 FFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY 837
Query: 1860 YGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG-FY 1918
G P + G C+P N + + GS + +G+ +C NN G CN CA G F+
Sbjct: 838 EGNP----IQPGGKCRPVN-QEIVRCDERGSMGT-SGEACRCKNNVVGRLCNECADGSFH 891
Query: 1919 GDAIFSKNCTACIC 1932
C C C
Sbjct: 892 LSTRNPDGCLKCFC 905
Score = 118 bits (283), Expect = 5e-25
Identities = 71/208 (34%), Positives = 95/208 (45%), Gaps = 26/208 (12%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S+ C C GY G CE C A + +P L T C C+C+G+ + SCD + G
Sbjct: 706 SVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGT---CSGCSCNGHAS-----SCDPVYG 757
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTT--------GT 1946
CL C +NT G CN C GF+GDA+ + +C C C + S T T
Sbjct: 758 HCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 817
Query: 1947 C-VCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIA--SESTQCDDDNGQCRCAKGV 2001
C C PG G +C+ CAP + G + G C P N I E CRC V
Sbjct: 818 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNV 877
Query: 2002 TGKQCDQCAAGFWNYT---KDGCDHCNC 2026
G+ C++CA G ++ + DGC C C
Sbjct: 878 VGRLCNECADGSFHLSTRNPDGCLKCFC 905
Score = 111 bits (268), Expect = 3e-23
Identities = 67/202 (33%), Positives = 88/202 (43%), Gaps = 32/202 (15%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C+C Y G +C C GY P TC+ C+C C+ +G C C+
Sbjct: 1105 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHS---EACEPETGACQGCQHHT 1161
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNC--DPT-GSTSTSC--SADGK--CN-CLTNFG 573
GPRC+QC GYY G + C C C DP G + +C DG C+ C
Sbjct: 1162 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1221
Query: 574 GAQCDQCSPGYYKYPD----C---------LSCNCDVSGSIGSTCDDNGLCHCKSNFDGA 620
G C++C+PGYY P C + CNCD GS+ S CD G C CK+ +G
Sbjct: 1222 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 1281
Query: 621 KCDTCREQFYNYPACEECNCDP 642
C CR ++ A C P
Sbjct: 1282 TCSHCRPHHFHLSASNPDGCLP 1303
Score = 102 bits (245), Expect = 2e-20
Identities = 72/226 (31%), Positives = 103/226 (45%), Gaps = 41/226 (18%)
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTST 558
+ +G +P++ +V QC C G+ GP C C +GY G C C+C S
Sbjct: 1092 EETGQDPAL--EVE-QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSE 1145
Query: 559 SCSAD-GKCN-CLTNFGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC-- 605
+C + G C C + G +C+QC PGYY DC C C +G TC
Sbjct: 1146 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFL 1205
Query: 606 --DDNGLCH-CKSNFDGAKCDTCREQFYNYPA----CEE---------CNCDPRGVTASF 649
D + C C G C+ C +Y P+ C+ CNCDP+G +S
Sbjct: 1206 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS- 1264
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C + AG+ CQCK +V+G C+ C+P +++L NP GC C C
Sbjct: 1265 -QCDA--AGQ-CQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1306
Score = 101 bits (242), Expect = 5e-20
Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 38/210 (18%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLCP-C 427
E +C C P ++ P C C GY P+ C+ C+C+ E C P G C C
Sbjct: 1101 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGC 1157
Query: 428 KYNYAGKSCEICEDGYYS-------PECKNCEC---NTVGSVSYVCDKLT-GDCTCKS-- 474
+++ G CE C+ GYY +C+ C C G ++ C T G TC +
Sbjct: 1158 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1217
Query: 475 -KYSGRTCNQCQAGYYNYPT----CK---------PCNCDTSGTEPSICDDVSGQCICKA 520
+SGR C +C GYY P+ C+ CNCD G+ S C D +GQC CKA
Sbjct: 1218 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAAGQCQCKA 1276
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
G C C ++ C+PC C
Sbjct: 1277 QVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1306
Score = 92.7 bits (220), Expect = 2e-17
Identities = 61/202 (30%), Positives = 88/202 (43%), Gaps = 26/202 (12%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKC-NCLTN 571
+C C G+ G C+ C ++ +V G C C+C+ G S+ G C NC N
Sbjct: 709 ECRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCSCN--GHASSCDPVYGHCLNCQHN 765
Query: 572 FGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC----DDNGLCH-CKSNF 617
G QC++C G++ C C C D S TC D C C +
Sbjct: 766 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 825
Query: 618 DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC---GSV-PAGELCQCKDRVQGRICN 673
G +C++C + P C P V C GS+ +GE C+CK+ V GR+CN
Sbjct: 826 TGRRCESCAPGYEGNPIQPGGKCRP--VNQEIVRCDERGSMGTSGEACRCKNNVVGRLCN 883
Query: 674 DCKPLYWNLQEYNPFGCEQCNC 695
+C ++L NP GC +C C
Sbjct: 884 ECADGSFHLSTRNPDGCLKCFC 905
Score = 87.0 bits (206), Expect = 1e-15
Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C PGY G C+ CA GY + L+ G +C+ C C+G+ + C G C +
Sbjct: 1509 CRCPPGYIGLSCQDCAPGY--TRTGSGLYLG-HCELCECNGHSD-----LCHPETGACSQ 1560
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFS--KNCTACIC-----DEFGMADCDSTTG---TC-VC 1949
C +N AG C LCAPG+YGDA ++C C C + C+S C C
Sbjct: 1561 CQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTAC 1620
Query: 1950 RPGVIGEKCDRCAPDHWG 1967
PG G+ C++C P + G
Sbjct: 1621 EPGYTGQYCEQCGPGYVG 1638
Score = 86.2 bits (204), Expect = 2e-15
Identities = 65/222 (29%), Positives = 93/222 (41%), Gaps = 38/222 (17%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCE-CRPEF 385
+C G +C C Y R + L C+ C C H CE E+G C+ C+
Sbjct: 1106 SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGHSEA--CEPETGACQGCQHHT 1161
Query: 386 QPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE--H-C-TPTDG--LCP-CKYNYA 432
+ P C C GY+ +C+ C C + G+ H C TDG C C ++
Sbjct: 1162 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1221
Query: 433 GKSCEICEDGYY-SPE----CKN---------CECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G+ CE C GYY +P C+ C C+ GSVS CD G C CK++ G
Sbjct: 1222 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEG 1280
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
TC+ C+ +++ P C P C ++ QC A
Sbjct: 1281 LTCSHCRPHHFHLSASNPDGC-----LPCFCMGITQQCASSA 1317
Score = 85.0 bits (201), Expect = 5e-15
Identities = 60/215 (27%), Positives = 91/215 (42%), Gaps = 29/215 (13%)
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDS 1942
P++ G ++ + C G +C C G+ ++ C C C A C+
Sbjct: 1091 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA-CEP 1149
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC------GIASESTQCDDD- 1991
TG C C+ G +C++C P ++G T C C C G A+ + D D
Sbjct: 1150 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDG 1209
Query: 1992 NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---------CNCNTGYSVGFMCNAT 2039
+ C C+ G +G+ C++CA G++ G C CNC+ SV C+A
Sbjct: 1210 HPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA 1269
Query: 2040 GQCECLPGVIGEKCDRC-PERWVLIPQ--EGCLEC 2071
GQC+C V G C C P + L +GCL C
Sbjct: 1270 GQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 1304
Score = 83.0 bits (196), Expect = 2e-14
Identities = 58/205 (28%), Positives = 86/205 (41%), Gaps = 26/205 (12%)
Query: 316 NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE 375
+GR +C C G++C C + R G + L C C C+ H S+ C+
Sbjct: 701 HGRAHSVEEC-RCPIGYSGLSCESCDAHFTRVPGGPY--LGTCSGCSCNGHASS--CDPV 755
Query: 376 SGRC-ECRPEFQPPDCSSCAYGYFD------YPNCKPCTC---NLNGTEGEHC-TPTDGL 424
G C C+ + P C+ C G+F +C+PC C + + + C TDG
Sbjct: 756 YGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQ 815
Query: 425 CPCKY---NYAGKSCEICEDGYY-SPECKNCECNTVGSVSYVCDK-----LTGD-CTCKS 474
C Y G+ CE C GY +P +C V CD+ +G+ C CK+
Sbjct: 816 ATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKN 875
Query: 475 KYSGRTCNQCQAGYYNYPTCKPCNC 499
GR CN+C G ++ T P C
Sbjct: 876 NVVGRLCNECADGSFHLSTRNPDGC 900
Score = 82.6 bits (195), Expect = 2e-14
Identities = 67/235 (28%), Positives = 91/235 (38%), Gaps = 42/235 (17%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC G C C + F R+ +C C+C+ H + C DP
Sbjct: 710 CRCPIGYSGLSCESCDAHFT----RVPGGPYLGTCSGCSCNGHASSC--DPVY------- 756
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC-----DPHFS 368
G CLNCQHNTEG CNKC+ ++ K C+PC C FS
Sbjct: 757 ---------GHCLNCQHNTEGPQCNKCKAGFFGDAMKA--TATSCRPCPCPYIDASRRFS 805
Query: 369 TGNCEEESGR--CE-CRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHCTP 420
+ G+ C+ C P + C SCA GY P C+P + +
Sbjct: 806 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMG 865
Query: 421 TDG-LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKS 474
T G C CK N G+ C C DG + +N + G + C ++ CT S
Sbjct: 866 TSGEACRCKNNVVGRLCNECADGSFHLSTRNPD----GCLKCFCMGVSRHCTSSS 916
Score = 79.8 bits (188), Expect = 2e-13
Identities = 55/202 (27%), Positives = 83/202 (41%), Gaps = 23/202 (11%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD------CLSCNCDVSGSIGSTCDD-NGLC-HCKSN 616
+C C + G C+ C + + P C C+C+ S+CD G C +C+ N
Sbjct: 709 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCN---GHASSCDPVYGHCLNCQHN 765
Query: 617 FDGAKCDTCREQFYN------YPACEECNCDPRGVTASFAG-CGSVPAGEL-CQ-CKDRV 667
+G +C+ C+ F+ +C C C + F+ C G+ C C
Sbjct: 766 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 825
Query: 668 QGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
GR C C P Y P G C N + + G+ T C CK +V R C+
Sbjct: 826 TGRRCESCAPGYEG-NPIQPGGKCRPVNQEIV-RCDERGSMGTSGEACRCKNNVVGRLCN 883
Query: 727 QCLDGFYRLQTNDVFGCTECDC 748
+C DG + L T + GC +C C
Sbjct: 884 ECADGSFHLSTRNPDGCLKCFC 905
Score = 78.2 bits (184), Expect = 5e-13
Identities = 69/248 (27%), Positives = 94/248 (37%), Gaps = 52/248 (20%)
Query: 244 DPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYD 303
DPA L + C C GP C C +G+ R +CE C+CH H+ C +
Sbjct: 1097 DPA--LEVEQCSCPPGYRGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--E 1148
Query: 304 PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC 363
PE G C CQH+TEG C +C+P YY +R D CQ C C
Sbjct: 1149 PET----------------GACQGCQHHTEGPRCEQCQPGYYGD-AQRGTPQD-CQLCPC 1190
Query: 364 --DPHF--STGNC---EEESGRCE-CRPEFQPPDCSSCAYGYFDYPN----CK------- 404
DP + C + C+ C P C CA GY+ P+ C+
Sbjct: 1191 YGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 1250
Query: 405 --PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
C C+ G+ C G C CK G +C C ++ N + G +
Sbjct: 1251 PIGCNCDPQGSVSSQCDAA-GQCQCKAQVEGLTCSHCRPHHFHLSASNPD----GCLPCF 1305
Query: 463 CDKLTGDC 470
C +T C
Sbjct: 1306 CMGITQQC 1313
Score = 77.4 bits (182), Expect = 9e-13
Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 1137 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 1185
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + + ++ +G C C G +C +C P YY P
Sbjct: 1186 QLCPCYG-------DPAAGQAAHTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNP 1236
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----- 398
+ + D P C CDP S + + +G+C+C+ + + CS C +F
Sbjct: 1237 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSAS 1296
Query: 399 DYPNCKPCTC 408
+ C PC C
Sbjct: 1297 NPDGCLPCFC 1306
Score = 74.9 bits (176), Expect = 5e-12
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPDCL---SCN-CDVSGSIGSTCDDNGLCH-CKSNFDG 619
+C+C + G C C GY + P L +C C G + + G C C+ + +G
Sbjct: 1104 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1163
Query: 620 AKCDTCREQFYNYPA------CEECNC--DPRGVTASFAGCGSVPAGELCQ-CKDRVQGR 670
+C+ C+ +Y C+ C C DP A+ C C GR
Sbjct: 1164 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1223
Query: 671 ICNDCKPLYW-NLQEYNPF-------GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C C P Y+ N + P G CNC+ G+++S C+ +GQC CK V
Sbjct: 1224 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS--QCDA-AGQCQCKAQVEG 1280
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDC 748
C C + L ++ GC C C
Sbjct: 1281 LTCSHCRPHHFHLSASNPDGCLPCFC 1306
Score = 73.7 bits (173), Expect = 1e-11
Identities = 48/146 (32%), Positives = 64/146 (43%), Gaps = 24/146 (16%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGY------FDYPNCKPCTCNLNGTEGEHCTPTDGLCP-C 427
E C C P + C CA GY +C+ C CN + C P G C C
Sbjct: 1505 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQC 1561
Query: 428 KYNYAGKSCEICEDGYY------SPE-CKNCEC---NTVGSVSYVCDKLTGD---CT-CK 473
++N AG+ CE+C GYY +PE C+ C C N S C+ L CT C+
Sbjct: 1562 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACE 1621
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNC 499
Y+G+ C QC GY P+ + C
Sbjct: 1622 PGYTGQYCEQCGPGYVGNPSVQGGQC 1647
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/196 (27%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQ-C 663
C C + G C C + P+ CE C+C P CQ C
Sbjct: 1105 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE-------PETGACQGC 1157
Query: 664 KDRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCN---LAGTLNSLGACNTKSGQ-C-VCK 717
+ +G C C+P Y+ + Q P C+ C C AG +T C C
Sbjct: 1158 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1217
Query: 718 QHVGERQCDQCLDGFYR--------LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHS 769
R C++C G+Y + + V G C+CD GS+ + CD GQC C +
Sbjct: 1218 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKA 1276
Query: 770 RVEGRRCDQPIRAHYF 785
+VEG C R H+F
Sbjct: 1277 QVEGLTCSH-CRPHHF 1291
Score = 70.9 bits (166), Expect = 8e-11
Identities = 62/197 (31%), Positives = 74/197 (37%), Gaps = 34/197 (17%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGHA +C+P G+ CQHNT GPQCNKC +GF + + SC P
Sbjct: 743 CSCNGHASSCDPV--YGHC----LNCQHNTEGPQCNKCKAGFFGDAMKATAT----SCRP 792
Query: 291 CNCHNHTTECTYDPEID-EKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C P ID +R S +G C C G C C P Y G
Sbjct: 793 CPC----------PYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY---EG 839
Query: 350 KRWDELDVCQP-----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
C+P +CD S G E C C+ C+ CA G F
Sbjct: 840 NPIQPGGKCRPVNQEIVRCDERGSMGTSGE---ACRCKNNVVGRLCNECADGSFHLSTRN 896
Query: 405 PCTCNLNGTEG--EHCT 419
P C G HCT
Sbjct: 897 PDGCLKCFCMGVSRHCT 913
Score = 70.5 bits (165), Expect = 1e-10
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 24/144 (16%)
Query: 425 CPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDCT-CKSKY 476
C C Y G SC+ C GY Y C+ CECN S +C TG C+ C+
Sbjct: 1509 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN---GHSDLCHPETGACSQCQHNA 1565
Query: 477 SGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSI---CDDVSG---QCI-CKAGFG 523
+G C C GYY T C+PC C + E C+ + +C C+ G+
Sbjct: 1566 AGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYT 1625
Query: 524 GPRCDQCLSGYYMQVLGRERQCVP 547
G C+QC GY + QC+P
Sbjct: 1626 GQYCEQCGPGYVGNPSVQGGQCLP 1649
Score = 68.5 bits (160), Expect = 4e-10
Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 30/210 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLC-PCKYNY 431
C C + C SC + P C C+CN + + C P G C C++N
Sbjct: 710 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASS---CDPVYGHCLNCQHNT 766
Query: 432 AGKSCEICEDGYY-------SPECKNCECNTVGSVSYVCDKL----TGDCTCKS---KYS 477
G C C+ G++ + C+ C C + + D G TC + Y+
Sbjct: 767 EGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYT 826
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD-----VSGQ-CICKAGFGGPRCDQCL 531
GR C C GY P C E CD+ SG+ C CK G C++C
Sbjct: 827 GRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECA 886
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCS 561
G + C+ C C TS S
Sbjct: 887 DGSFHLSTRNPDGCLKCFCMGVSRHCTSSS 916
Score = 66.9 bits (156), Expect = 1e-09
Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 19/143 (13%)
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPT------CKPCNCDTSGTEPSICDDVSGQCI-CKAG 521
+C C Y G +C C GY + C+ C C+ +C +G C C+
Sbjct: 1508 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHS---DLCHPETGACSQCQHN 1564
Query: 522 FGGPRCDQCLSGYYMQVL-GRERQCVPCNC---DPTGSTSTSCSADG----KCN-CLTNF 572
G C+ C GYY G C PC C +P S +C + G +C C +
Sbjct: 1565 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1624
Query: 573 GGAQCDQCSPGYYKYPDCLSCNC 595
G C+QC PGY P C
Sbjct: 1625 TGQYCEQCGPGYVGNPSVQGGQC 1647
Score = 65.3 bits (152), Expect = 4e-09
Identities = 53/197 (26%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 1900 KCVNNTAGAACNLCAPGF--YGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGE 1956
+C +G +C C F + C+ C C+ + CD G C+ C+ G
Sbjct: 711 RCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHA-SSCDPVYGHCLNCQHNTEGP 769
Query: 1957 KCDRCAPDHWG---LNTGLGCTPCNCGIASESTQCDDD-----NGQCRC---AKGVTGKQ 2005
+C++C +G T C PC C S + D +GQ C A G TG++
Sbjct: 770 QCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRR 829
Query: 2006 CDQCAAGF-WNYTKDG--CDHCN-----CNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
C+ CA G+ N + G C N C+ S+G A C C V+G C+ C
Sbjct: 830 CESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEA---CRCKNNVVGRLCNECA 886
Query: 2058 ERWVLIP---QEGCLEC 2071
+ + +GCL+C
Sbjct: 887 DGSFHLSTRNPDGCLKC 903
Score = 62.9 bits (146), Expect = 2e-08
Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN-CGIASESTQCDDDNGQC-RCAKGVTGK 2004
C C PG IG C CAP + +GL C C S C + G C +C G+
Sbjct: 1509 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGE 1568
Query: 2005 QCDQCAAGFWN----YTKDGCDHCNC---NTGYSVGFMCNATG----QC-ECLPGVIGEK 2052
C+ CA G++ T + C C C N C + G +C C PG G+
Sbjct: 1569 FCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQY 1628
Query: 2053 CDRCPERWV 2061
C++C +V
Sbjct: 1629 CEQCGPGYV 1637
Score = 61.7 bits (143), Expect = 5e-08
Identities = 50/175 (28%), Positives = 72/175 (41%), Gaps = 31/175 (17%)
Query: 1340 CLCDFMGSTELECNTFGGQC-PCKPNVIGRTCSACRTGYYG------FPNCRPCHCP--- 1389
C C+ S+ C+ G C C+ N G C+ C+ G++G +CRPC CP
Sbjct: 743 CSCNGHASS---CDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYID 799
Query: 1390 ------STAICDDNGMC---ICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGN 1440
T D +G C G C+ C P +Q G N V +
Sbjct: 800 ASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCD 859
Query: 1441 QLQCEADSGK-CACRENVRGRVCDHCVPGHYAF----PD-CYQCTC---NRHGTT 1486
+ SG+ C C+ NV GR+C+ C G + PD C +C C +RH T+
Sbjct: 860 ERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTS 914
Score = 61.3 bits (142), Expect = 6e-08
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 16/140 (11%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC-ECRPEFQ 386
C G++C C P Y R + L C+ C+C+ H + C E+G C +C+
Sbjct: 1511 CPPGYIGLSCQDCAPGYTRTGSGLY--LGHCELCECNGH--SDLCHPETGACSQCQHNAA 1566
Query: 387 PPDCSSCAYGYF------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C CA GY+ +C+PC C L E + L G C CE
Sbjct: 1567 GEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESL-----GAGGYRCTACE 1621
Query: 441 DGYYSPECKNCECNTVGSVS 460
GY C+ C VG+ S
Sbjct: 1622 PGYTGQYCEQCGPGYVGNPS 1641
Score = 58.0 bits (134), Expect = 6e-07
Identities = 49/175 (28%), Positives = 61/175 (34%), Gaps = 32/175 (18%)
Query: 242 PADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECT 301
P++ L + CRC G C C G+ R CE C C+ H+ C
Sbjct: 1497 PSNRPRALEVEECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLC- 1551
Query: 302 YDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
PE G C CQHN G C C P YY E CQPC
Sbjct: 1552 -HPET----------------GACSQCQHNAAGEFCELCAPGYYGDATAGTPE--DCQPC 1592
Query: 362 QC---DP-HFSTGNCEEESG---RC-ECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
C +P + + CE RC C P + C C GY P+ + C
Sbjct: 1593 ACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1647
Score = 56.4 bits (130), Expect = 2e-06
Identities = 51/180 (28%), Positives = 84/180 (46%), Gaps = 19/180 (10%)
Query: 3022 SFNGTDSYLRFVDVTSENPQLTL--KFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGK 3079
S +G SYL +T+ + +L L +FK P+G+L S ++ + D +SL++V G
Sbjct: 3910 SLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLF--SGGKSGPVEDFVSLAMVGGH 3967
Query: 3080 LVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDG-- 3137
L R +L +GL ++ L H SA +L D + P L G
Sbjct: 3968 LEF---RYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGS--LRVNGGRPVLRSSPGKS 4022
Query: 3138 -------VLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
+L++GGV+P +S + F GC+G+ ++NG+ L+L F S G+C
Sbjct: 4023 QGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL-GSQGIGQC 4081
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 19/141 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTA-ICD-DNGMCI-CPKNVEG 1408
+C C P IG +C C GY +C C C + +C + G C C N G
Sbjct: 1508 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAG 1567
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNC---NPLGVVGNQLQCEADSG-KC-ACRENVRG 1459
E C+ C P + D G C C C NP + + G +C AC G
Sbjct: 1568 EFCELCAPGYYG-DATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTG 1626
Query: 1460 RVCDHCVPGHYAFPDCYQCTC 1480
+ C+ C PG+ P C
Sbjct: 1627 QYCEQCGPGYVGNPSVQGGQC 1647
Score = 51.2 bits (117), Expect = 7e-05
Identities = 41/182 (22%), Positives = 65/182 (35%), Gaps = 21/182 (11%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C++C F P C C+C+ + C V G C+
Sbjct: 710 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHA-----SSCDPV-YGHCLNCQ 763
Query: 665 DRVQGRICNDCKP-LYWNLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKS-GQCVCKQ--- 718
+G CN CK + + + C C C C + GQ C
Sbjct: 764 HNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 823
Query: 719 -HVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ-CHCHSRVEGRRC 776
+ G R+C+ C G+ C + +I + T+G+ C C + V GR C
Sbjct: 824 GYTG-RRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 882
Query: 777 DQ 778
++
Sbjct: 883 NE 884
Score = 49.2 bits (112), Expect = 3e-04
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 19/114 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH+D C P A +CQHN G C C G+ + + C+P
Sbjct: 1542 CECNGHSDLCHPETGA------CSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQP 1591
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C C +P E S GG +C C+ G C +C P Y
Sbjct: 1592 CACP------LTNP---ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGY 1636
Score = 48.0 bits (109), Expect = 6e-04
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK
Sbjct: 1226 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQ 1277
Query: 1365 VIGRTCSACRTGYYGF-----PNCRPCHC 1388
V G TCS CR ++ C PC C
Sbjct: 1278 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 1306
Score = 47.6 bits (108), Expect = 8e-04
Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 21/106 (19%)
Query: 1341 LCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF------PNCRPCHCPST-- 1391
LC+ G ++L C+ G C C+ N G C C GYYG +C+PC CP T
Sbjct: 1541 LCECNGHSDL-CHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNP 1599
Query: 1392 -----AICDDNG----MC-ICPKNVEGENCDRCKP-YTFNFDVQRG 1426
C+ G C C G+ C++C P Y N VQ G
Sbjct: 1600 ENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGG 1645
Score = 47.2 bits (107), Expect = 0.001
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 14/138 (10%)
Query: 3516 SISMEVRPRNTTGLLL-------SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSN 3568
+I +EVR +GLLL KD++ L L D +V + G+G R L +
Sbjct: 4208 TIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEAR----LVS 4263
Query: 3569 KHYLCDGNWHKIHXXXXXXXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKV 3626
+ + DG WH++ DG S G + + ++YIGG + +
Sbjct: 4264 EDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAP-DVATL 4322
Query: 3627 RGVHSRRGFTGCVRNIVV 3644
G G TGCV+N+V+
Sbjct: 4323 TGGRFSSGITGCVKNLVL 4340
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 2890 GEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD- 2948
G+G F SL +QDG + + LG+ E ++ + NDG+WH++ A R + S+ VD
Sbjct: 4233 GQGKDFISLGLQDGHLVFRYQLGSGEARLV--SEDPINDGEWHRVTALREGRRGSIQVDG 4290
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDR---GFDGCMRQISIN 2996
E++ S P+ + + ++ GG R G GC++ + ++
Sbjct: 4291 EELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4341
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 2877 FRTYAPNG-LIYLVGEGGY---FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWH 2932
F+ AP+G L++ G+ G F SL M G + + LG+ L ++ + G+WH
Sbjct: 3936 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGS--GLAVLRSAEPLALGRWH 3993
Query: 2933 KLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNF-GGNNKGILQVPDRG----FD 2987
++ A R SL V+ S+ + +L T+ + GG + P F
Sbjct: 3994 RVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFR 4053
Query: 2988 GCMRQISINGVNLDLSENL---ESIGMAY 3013
GC+ ++S+NG LDL+ + + IG Y
Sbjct: 4054 GCVGEVSVNGKRLDLTYSFLGSQGIGQCY 4082
Score = 44.0 bits (99), Expect = 0.010
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 3361 FLAFFMRDAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVD-SEMVGET 3419
F++ ++D L + + G + S ND +WH VT R G G + VD E+V
Sbjct: 4238 FISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGR 4297
Query: 3420 SVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMN 3466
S N ++ Y GG V + F GC+K L+++
Sbjct: 4298 SPGPNVAVNAKGSVYIGGAPDV---ATLTGGRFSSGITGCVKNLVLH 4341
Score = 43.2 bits (97), Expect = 0.018
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 8/95 (8%)
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQC-VC 716
E C+C G C DC P Y G CE C CN L C+ ++G C C
Sbjct: 1507 EECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL-----CHPETGACSQC 1561
Query: 717 KQHVGERQCDQCLDGFYRLQT-NDVFGCTECDCDI 750
+ + C+ C G+Y T C C C +
Sbjct: 1562 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPL 1596
Score = 42.7 bits (96), Expect = 0.024
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 15/72 (20%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKDG-------CDHCNCNTGYSVGFMCN-ATGQC-EC 2044
+CRC G G C CA G YT+ G C+ C CN G+S +C+ TG C +C
Sbjct: 1508 ECRCPPGYIGLSCQDCAPG---YTRTGSGLYLGHCELCECN-GHS--DLCHPETGACSQC 1561
Query: 2045 LPGVIGEKCDRC 2056
GE C+ C
Sbjct: 1562 QHNAAGEFCELC 1573
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 16/195 (8%)
Query: 3478 NALRCVDNIEDGVYFEA-SNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGK 3536
+ LRC E+GV S + +YL L E+ + +E +P G+LL GK
Sbjct: 3896 SGLRC----EEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGK 3951
Query: 3537 ----KDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXX 3592
+D++ L ++ + E G+G L + L G WH++
Sbjct: 3952 SGPVEDFVSLAMVGGHLEFRYELGSG----LAVLRSAEPLALGRWHRVSAERLNKDGSLR 4007
Query: 3593 XDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVK 3650
+G + G + H+ LY+GG E + + F GCV + V +
Sbjct: 4008 VNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLD 4067
Query: 3651 VPNSAVGRGAHVGVC 3665
+ S +G +G C
Sbjct: 4068 LTYSFLG-SQGIGQC 4081
Score = 39.1 bits (87), Expect = 0.30
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 21/147 (14%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT G +L+ G G + D++ +G+Q+G+ +G AR+ +
Sbjct: 4214 RTSTASGLLLWQGVEVG---EAGQGKDFISLGLQDGHLVFRYQLGSGE------ARLVSE 4264
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
+ D W++V R GRR + + +G + + + PG + N K +Y+
Sbjct: 4265 DPINDGEWHRVTALREGRRGSIQV-----DGEELVSGRS---PGPNVAVN---AKGSVYI 4313
Query: 2790 GGVPSDAKLQGISFPA-FEGQIEELMI 2815
GG P A L G F + G ++ L++
Sbjct: 4314 GGAPDVATLTGGRFSSGITGCVKNLVL 4340
Score = 38.7 bits (86), Expect = 0.39
Identities = 30/134 (22%), Positives = 45/134 (33%), Gaps = 18/134 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
C C + G C C + + CE C C+ + G QC+
Sbjct: 1509 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN------GHSDLCHPETGACSQCQ 1562
Query: 665 DRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCNLAGTLNSLG-ACNTKSG---QC-VCKQ 718
G C C P Y+ + P C+ C C L N C + +C C+
Sbjct: 1563 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1622
Query: 719 HVGERQCDQCLDGF 732
+ C+QC G+
Sbjct: 1623 GYTGQYCEQCGPGY 1636
Score = 37.5 bits (83), Expect = 0.90
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 1932 CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
C G D +S++ CVC G G +C+ + L C P CG + D
Sbjct: 3832 CQNGGQCHDSESSSYVCVCPAGFTGSRCEH--------SQALHCHPEACGPDATCVNRPD 3883
Query: 1991 DNG-QCRCAKGVTGKQCDQ 2008
G CRC G +G +C++
Sbjct: 3884 GRGYTCRCHLGRSGLRCEE 3902
Score = 37.1 bits (82), Expect = 1.2
Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 9/118 (7%)
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQCRCAKGVTGKQCDQCAA 2011
V G D P+ G + L C+C C D D G R G+ C++C+
Sbjct: 1081 VSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSC 1140
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATG-QCE-CLPGVIGEKCDRCPERWVLIPQEG 2067
+ C TG G + G +CE C PG G+ P+ L P G
Sbjct: 1141 ------HGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG 1192
Score = 37.1 bits (82), Expect = 1.2
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 13/83 (15%)
Query: 1737 QCPRAYRGLSCEQCAEGHYR-LPSGF---CVPCQC------NGHSDQCD-VNTG--ICLN 1783
QC G CE CA G+Y +G C PC C N S C+ + G C
Sbjct: 1560 QCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTA 1619
Query: 1784 CADNTIGDHCEFCMSGYHGDATV 1806
C G +CE C GY G+ +V
Sbjct: 1620 CEPGYTGQYCEQCGPGYVGNPSV 1642
Score = 36.3 bits (80), Expect = 2.1
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 12/94 (12%)
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCV 546
G + PTC+ C G + + S C+C AGF G RC+ + Q L C
Sbjct: 3820 GISHCPTCRDRPCQNGG-QCHDSESSSYVCVCPAGFTGSRCE------HSQAL----HCH 3868
Query: 547 PCNCDPTGSTSTSCSADG-KCNCLTNFGGAQCDQ 579
P C P + G C C G +C++
Sbjct: 3869 PEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEE 3902
Score = 34.7 bits (76), Expect = 6.4
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 15/130 (11%)
Query: 1269 TSKGVWLDYVLVIEASDFTDAVLTEANILDYTR-----EFIEQCASYNYYISPNETGL-C 1322
T G++L + + E + +D E + EF E CA Y + T C
Sbjct: 1530 TGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDC 1589
Query: 1323 REAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPN 1382
+ +T+ N +R C + +G+ C C+P G+ C C GY G P+
Sbjct: 1590 QPCACPLTNPENMFSRTC--ESLGAGGYRCTA------CEPGYTGQYCEQCGPGYVGNPS 1641
Query: 1383 CRPCHC-PST 1391
+ C P T
Sbjct: 1642 VQGGQCLPET 1651
>S77512-1|AAB34682.2| 1798|Homo sapiens laminin beta 2 chain protein.
Length = 1798
Score = 304 bits (746), Expect = 4e-81
Identities = 143/366 (39%), Positives = 192/366 (52%), Gaps = 21/366 (5%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C GL C++C G + PS C PC CNGH+D+C+ +TG CL C D+T G+HCE
Sbjct: 849 QCLCRTGAFGLRCDRCQRGQWGFPS--CRPCVCNGHADECNTHTGACLGCRDHTGGEHCE 906
Query: 1795 FCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++G+HGD + C C CP P +FA SC E I C+C+ GY G RCE
Sbjct: 907 RCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCE 966
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA G++G P G C+ C CSGNI+P DP +CD G CL+C+++T G C C
Sbjct: 967 ACAPGHFGDPS----RPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHC 1022
Query: 1914 APGFYGDAIFSKNCTACICDEFG----------MADCDSTTGTCVCRPGVIGEKCDRCAP 1963
PGF+G A ++C C C+ G CD ++G C C P V G CDRCAP
Sbjct: 1023 KPGFHGQAA-RQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAP 1081
Query: 1964 DHWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+ W L +G GC PC C + + C++ GQC C G G+ C +C W C
Sbjct: 1082 NFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCH 1141
Query: 2023 HCNCNT-GYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFS 2081
C+C++ G TG C C PGV G +CD+C + I C C +C
Sbjct: 1142 ACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARAFSGI-FPACHPCHACFGDWDRV 1200
Query: 2082 VEDLSA 2087
V+DL+A
Sbjct: 1201 VQDLAA 1206
Score = 257 bits (630), Expect = 5e-67
Identities = 149/467 (31%), Positives = 223/467 (47%), Gaps = 48/467 (10%)
Query: 50 YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDY 109
+A R WWQS G+ V + +DL EFH ++ + + RP ++E+S D+
Sbjct: 115 FAPQRRAAWWQS---ENGIP--AVTIQLDLEAEFHFTHLIMTF-KTFRPAAMLVERSADF 168
Query: 110 GKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR 169
G+T+ ++YFS DC F L P D V+C + YS+I P +GE+ +L+
Sbjct: 169 GRTWHVYRYFS---YDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPA 225
Query: 170 -PSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIG 228
P + Y SS +Q + TN+R+ L R L +L+ R+ + +Y+Y++ ++ +
Sbjct: 226 IPIPDPY--SSRIQNLLKITNLRVNLTRLHTLGDNLLDPRRE---IREKYYYALYELVVR 280
Query: 229 GRCMCNGHADTCEPAD--PAGNLNIL--VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
G C C GHA C PA PA ++ C C+HNT G C +C + WR +++
Sbjct: 281 GNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGH 340
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
+C C CH HT C +D +++ + GG C CQHNT G +C CRP +
Sbjct: 341 SHACRKCECHGHTHSCHFD-------MAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFF 393
Query: 345 YRPYGKRWDELDVCQPCQCDPHFST--GNCEEE--------SGRCECRPEFQPPDCSSCA 394
YR K + VC+ C CDP S G C+ SG+C C+ C C
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
Query: 395 YGYF-----DYPNCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE 447
G+F D C+ C CN GT C P G C CK G+ C+ C G++
Sbjct: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS 513
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
C+ C+C+ G++ CD+ TG C C+ GR C Q Q GY+
Sbjct: 514 HDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 243 bits (594), Expect = 1e-62
Identities = 140/425 (32%), Positives = 199/425 (46%), Gaps = 48/425 (11%)
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS---PECKNCECNTV 456
Y PC CN G+ C P G C CK G+ C++C GYY C+ C+C+
Sbjct: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHE 836
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC 516
G++S +C+K +G C C++ G C++CQ G + +P+C+PC C+ E C+ +G C
Sbjct: 837 GALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADE---CNTHTGAC 893
Query: 517 I-CKAGFGGPRCDQCLSGYYMQV-LGRERQCVPCNC-DPTGST---STSCSADG-----K 565
+ C+ GG C++C++G++ L QC PC C + GS +TSC D
Sbjct: 894 LGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIV 953
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPD-----CLSCNCDVSGSIG----STCDDN-GLC-HCK 614
C+C + G +C+ C+PG++ P C C C SG+I CD + G C C
Sbjct: 954 CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCEC--SGNIDPMDPDACDPHTGQCLRCL 1011
Query: 615 SNFDGAKCDTCREQFYNYPA---CEECNCDPRGVT----ASFAGCGSVPAGELCQCKDRV 667
+ +G C C+ F+ A C C C+ G S C P+ C C V
Sbjct: 1012 HHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
QG C+ C P +WNL + GC+ C C+ + CN +GQC C+ G R C +
Sbjct: 1072 QGPSCDRCAPNFWNLT--SGHGCQPCACHPSRARGP--TCNEFTGQCHCRAGFGGRTCSE 1127
Query: 728 CLDGFYRLQTNDV-FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH--Y 784
C + L D C CDCD G C + TG C C V G RCDQ RA
Sbjct: 1128 CQE----LHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARAFSGI 1183
Query: 785 FPTLH 789
FP H
Sbjct: 1184 FPACH 1188
Score = 194 bits (473), Expect = 5e-48
Identities = 119/394 (30%), Positives = 172/394 (43%), Gaps = 56/394 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGRCE 380
GG+CL C+ G C+ C P YY +G CQ CQC + + CE+ SG+C
Sbjct: 799 GGQCL-CKPGVVGRRCDLCAPGYYG-FGPTG-----CQACQCSHEGALSSLCEKTSGQCL 851
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEIC 439
CR C C G + +P+C+PC CN + E C G C C+ + G+ CE C
Sbjct: 852 CRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADE---CNTHTGACLGCRDHTGGEHCERC 908
Query: 440 EDGY-------YSPECKNCEC-NTVGSVSYVCDKLTGD-------CTCKSKYSGRTCNQC 484
G+ Y +C+ C C GS + D C C++ Y+G C C
Sbjct: 909 IAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEAC 968
Query: 485 QAGYYNYPT-----CKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYM 536
G++ P+ C+ C C + +P CD +GQC+ C GP C C G++
Sbjct: 969 APGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHG 1028
Query: 537 QVLGRERQCVPCNCDPTGSTSTSC---------SADGKCNCLTNFGGAQCDQCSPGYYKY 587
Q + C C C+ G+ C + G+C CL N G CD+C+P ++
Sbjct: 1029 Q--AARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNL 1086
Query: 588 PD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPA--CEECNCD 641
C C C S + G TC++ G CHC++ F G C C+E + P C C+CD
Sbjct: 1087 TSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCD 1146
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDC 675
RG+ C C C+ V G C+ C
Sbjct: 1147 SRGIDT--PQCHRFTGH--CSCRPGVSGVRCDQC 1176
Score = 192 bits (467), Expect = 3e-47
Identities = 122/412 (29%), Positives = 176/412 (42%), Gaps = 52/412 (12%)
Query: 360 PCQCDPHFS-TGNCEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGE 416
PCQC+P S + C G+C C+P C CA GY+ + C+ C C+ G
Sbjct: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSS 841
Query: 417 HCTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCT-CKS 474
C T G C C+ G C+ C+ G + P C+ C CN G C+ TG C C+
Sbjct: 842 LCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHAD-ECNTHTGACLGCRD 898
Query: 475 KYSGRTCNQCQAGYYNYP------TCKPCNC-DTSGTE---PSIC--DDVSGQ--CICKA 520
G C +C AG++ P C+PC C + G++ + C D+ S Q C C+A
Sbjct: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQ 576
G+ G RC+ C G++ +C C C + D G+C CL + G
Sbjct: 959 GYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPH 1018
Query: 577 CDQCSPGYY---KYPDCLSCNCDVSGSIGSTCDDNGLCHCK---------SNFDGAKCDT 624
C C PG++ C C C++ G+ C CHC N G CD
Sbjct: 1019 CAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDR 1078
Query: 625 CREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C F+N + C+ C C P A C G+ C C+ GR C++C+ L+W
Sbjct: 1079 CAPNFWNLTSGHGCQPCACHPS--RARGPTCNEF-TGQ-CHCRAGFGGRTCSECQELHWG 1134
Query: 682 LQEYNP-FGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGF 732
+P C C+C+ G C+ +G C C+ V +CDQC F
Sbjct: 1135 ----DPGLQCHACDCDSRGI--DTPQCHRFTGHCSCRPGVSGVRCDQCARAF 1180
Score = 171 bits (415), Expect = 5e-41
Identities = 108/345 (31%), Positives = 152/345 (44%), Gaps = 40/345 (11%)
Query: 540 GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------D 589
G +C P P G C C N G C+QC Y P
Sbjct: 287 GHASECAPA---PGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA 343
Query: 590 CLSCNC---------DVSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA----- 634
C C C D++ + S G+C C+ N G C+ CR FY P
Sbjct: 344 CRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRD 403
Query: 635 ---CEECNCDPRGVTASFAGCGSV--PAGEL----CQCKDRVQGRICNDCKPLYWNLQEY 685
C C+CDP G + C S PA L C+CK+ V G C C+ ++ L
Sbjct: 404 PAVCRSCDCDPMG-SQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSIS 462
Query: 686 NPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE 745
+ GC +C CN GT+ C+ SG C CK+ V R CD+CL G + L ++D+ GC
Sbjct: 463 DRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRP 521
Query: 746 CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSGPV 805
CDCD+GG++D CD+ TGQCHC + GRRC+Q ++ P L +E ED Q V
Sbjct: 522 CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRGQVLDV 581
Query: 806 RYR-NSEEVFPEYSWKGYVVFSLLQNEVINIIQITKSSLYRMVLK 849
R + P ++ G+V Q + + K+ Y ++L+
Sbjct: 582 VERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPKAMDYDLLLR 626
Score = 166 bits (404), Expect = 1e-39
Identities = 116/368 (31%), Positives = 139/368 (37%), Gaps = 54/368 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGH---SDQCDVNTGICLNCADNTIGD 1791
+C C G C+ CA G+Y C CQC+ S C+ +G CL C G
Sbjct: 801 QCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCL-CRTGAFGL 859
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C+ C G G + C C C N A C+ L C+ GG
Sbjct: 860 RCDRCQRGQWGFPS------CRPCVC------NGHADECNTHTGACL---GCRDHTGGEH 904
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC----------LKC 1901
CE C AG++G P L G C+PC C P+ PGS C C
Sbjct: 905 CERCIAGFHGDPR---LPYGGQCRPCPC-----PEGPGSQRHFATSCHQDEYSQQIVCHC 956
Query: 1902 VNNTAGAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIG 1955
G C CAPG +GD + C C C D CD TG C+ C G
Sbjct: 957 RAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEG 1016
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ---------CDDDNGQCRCAKGVTGKQC 2006
C C P G C C C + + Q CD +GQC C V G C
Sbjct: 1017 PHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSC 1076
Query: 2007 DQCAAGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIP 2064
D+CA FWN T GC C C+ + G CN TGQC C G G C C E P
Sbjct: 1077 DRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDP 1136
Query: 2065 QEGCLECD 2072
C CD
Sbjct: 1137 GLQCHACD 1144
Score = 164 bits (399), Expect = 5e-39
Identities = 120/449 (26%), Positives = 172/449 (38%), Gaps = 80/449 (17%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN +P G C C+ G +C+ C G+ + C+
Sbjct: 783 CQCNPQGSLSSECNPHGGQ----CLCKPGVVGRRCDLCAPGY--------YGFGPTGCQA 830
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C +H + + EK G+CL C+ G+ C++C+
Sbjct: 831 CQC-SHEGALS---SLCEKT-----------SGQCL-CRTGAFGLRCDRCQ-------RG 867
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NC 403
+W C+PC C+ H C +G C CR C C G+ P C
Sbjct: 868 QWG-FPSCRPCVCNGH--ADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQC 924
Query: 404 KPCTCNLN-GTEGEHCTPTDG-------LCPCKYNYAGKSCEICEDGYYSP------ECK 449
+PC C G++ T +C C+ Y G CE C G++ C+
Sbjct: 925 RPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQ 984
Query: 450 NCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYNY---PTCKPCNCDTSG 503
CEC N CD TG C C G C C+ G++ +C C C+ G
Sbjct: 985 LCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLG 1044
Query: 504 TEPS--------ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGS 555
T P CD SGQC C GP CD+C ++ G C PC C P+ +
Sbjct: 1045 TNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSG--HGCQPCACHPSRA 1102
Query: 556 TSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKYP--DCLSCNCDVSGSIGSTCDD-NGLC 611
+C+ G+C+C FGG C +C ++ P C +C+CD G C G C
Sbjct: 1103 RGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHC 1162
Query: 612 HCKSNFDGAKCDTCREQFYN-YPACEECN 639
C+ G +CD C F +PAC C+
Sbjct: 1163 SCRPGVSGVRCDQCARAFSGIFPACHPCH 1191
Score = 147 bits (357), Expect = 6e-34
Identities = 93/282 (32%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 1765 CQCNGHSDQC-----------DVNTGICLNCADNTIGDHCEFCMSGYHG----DATVGTP 1809
C C GH+ +C + G C+ C NT G +CE C Y A G
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
Query: 1810 RDCLICACPMPYPSNNFALSCDL-SENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTD 1867
C C C S +F ++ L S N S C+ CQ G CE C +Y P D
Sbjct: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK-D 400
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDS--------INGDCLKCVNNTAGAACNLCAPGFYG 1919
L C+ C+C + QD G CDS ++G C +C + G C C GF+G
Sbjct: 401 LRDPAVCRSCDCDP-MGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFG 458
Query: 1920 DAIFSK-NCTACICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG-LG 1973
+I + C C C+ G CD +G+C C+ V G CDRC P HWGL+ LG
Sbjct: 459 LSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
Query: 1974 CTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
C PC+C + QCD+ GQC C + + G++C+Q G++
Sbjct: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 140 bits (338), Expect = 1e-31
Identities = 83/249 (33%), Positives = 115/249 (46%), Gaps = 36/249 (14%)
Query: 1840 SCNCQPGYGGARCEYCAAGYYGIP----EDTDLHTGDYCKPCNCSGNINPQD------PG 1889
+C C+ G CE C Y +P ED H C+ C C G+ +
Sbjct: 309 ACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA---CRKCECHGHTHSCHFDMAVYLA 365
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN----CTACICDEFGMAD---CDS 1942
S + G C C +NTAG C LC P FY D C +C CD G D CDS
Sbjct: 366 SGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDS 425
Query: 1943 --------TTGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC---GIASESTQCD 1989
+G C C+ V+G +C +C +GL+ LGC C C G ST CD
Sbjct: 426 HDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCD 485
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCN-ATGQCECLP 2046
++G C C + VTG+ CD+C G W + D GC C+C+ G ++ C+ TGQC C
Sbjct: 486 PNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQ 545
Query: 2047 GVIGEKCDR 2055
++G +C++
Sbjct: 546 HMVGRRCEQ 554
Score = 138 bits (333), Expect = 5e-31
Identities = 90/284 (31%), Positives = 124/284 (43%), Gaps = 35/284 (12%)
Query: 1273 VWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNETGLCREAMFSITSE 1332
V L VLV+E DA E + R + SP+E C + S+++
Sbjct: 719 VLLPRVLVLEMFSGGDAAALERQAT-FERYQCHEEGLVPSKTSPSEA--CAPLLISLSTL 775
Query: 1333 YNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNCRPCHCPS 1390
+GA PC C+ GS ECN GGQC CKP V+GR C C GYYGF C+ C C
Sbjct: 776 IYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSH 835
Query: 1391 ----TAICD-DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
+++C+ +G C+C G CDRC+ + F C C CN G+ +C
Sbjct: 836 EGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP---SCRPCVCN-----GHADECN 887
Query: 1446 ADSGKC-ACRENVRGRVCDHCVPGHYAFP------DCYQCTC------NRHGTTYDVCDQ 1492
+G C CR++ G C+ C+ G + P C C C RH T D+
Sbjct: 888 THTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDE 947
Query: 1493 NTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDG-CTKCFCFG 1533
+ Q C+C+ G C+ C +F P G C C C G
Sbjct: 948 YSQQIVCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSG 990
Score = 130 bits (314), Expect = 9e-29
Identities = 84/260 (32%), Positives = 118/260 (45%), Gaps = 38/260 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC-----------DV 1776
C C RGL+CEQC + + LP S C C+C+GH+ C +V
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
Query: 1777 NTGICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ G+C C NT G HCE C ++ D T + P C C C P S + CD +
Sbjct: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCD-PMGSQDGG-RCDSHD 427
Query: 1835 NGS--LIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS 1890
+ + L+S C C+ G RC+ C G++G+ L C+ C C N PGS
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLG----CRRCQC--NARGTVPGS 481
Query: 1891 --CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CD +G C C G C+ C PG +G + C C CD G D CD TG
Sbjct: 482 TPCDPNSGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQ 540
Query: 1947 CVCRPGVIGEKCDRCAPDHW 1966
C CR ++G +C++ P ++
Sbjct: 541 CHCRQHMVGRRCEQVQPGYF 560
Score = 127 bits (306), Expect = 9e-28
Identities = 86/293 (29%), Positives = 127/293 (43%), Gaps = 55/293 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYR--PY 348
C C+ H +EC P G G C+ C+HNT G+NC +C+ +YR P+
Sbjct: 283 CFCYGHASECAPAPGAPAHA-----EGMVHGA--CI-CKHNTRGLNCEQCQD-FYRDLPW 333
Query: 349 GKRWD-ELDVCQPCQCDPH-----------FSTGNCEEESGRCE-CRPEFQPPDCSSCAY 395
D C+ C+C H ++GN G C+ C+ C C
Sbjct: 334 RPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS--GGVCDGCQHNTAGRHCELCRP 391
Query: 396 GYFDYPN--------CKPCTCNLNGTE-GEHCTPTD--------GLCPCKYNYAGKSCEI 438
++ P C+ C C+ G++ G C D G C CK + G C+
Sbjct: 392 FFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ 451
Query: 439 CEDGYYSPE------CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYN 490
C DG++ C+ C+CN G+V S CD +G C CK +GR C++C G++
Sbjct: 452 CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Query: 491 YPT----CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
C+PC+CD G CD+ +GQC C+ G RC+Q GY+ L
Sbjct: 512 LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFL 564
Score = 122 bits (294), Expect = 2e-26
Identities = 77/253 (30%), Positives = 114/253 (45%), Gaps = 45/253 (17%)
Query: 423 GLCPCKYNYAGKSCEICEDGY-----------YSPECKNCECNTVG-------SVSYVCD 464
G C CK+N G +CE C+D Y +S C+ CEC+ +V
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 465 KLTGD-CT-CKSKYSGRTCNQCQAGYYNYPT--------CKPCNCDTSGTEPS-ICDD-- 511
++G C C+ +GR C C+ +Y PT C+ C+CD G++ CD
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 512 ------VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST--STSCSAD 563
VSGQC CK G RC QC G++ + C C C+ G+ ST C +
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 564 -GKCNCLTNFGGAQCDQCSPGYYKYP----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNF 617
G C C G CD+C PG++ C C+CDV G++ CD+ G CHC+ +
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 618 DGAKCDTCREQFY 630
G +C+ + ++
Sbjct: 548 VGRRCEQVQPGYF 560
Score = 115 bits (277), Expect = 3e-24
Identities = 62/193 (32%), Positives = 85/193 (44%), Gaps = 29/193 (15%)
Query: 1353 NTFGGQCP-CKPNVIGRTCSACRTGYYGFPN--------CRPCHCPSTAI-----CDDN- 1397
N GG C C+ N GR C CR +Y P CR C C CD +
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 1398 --------GMCICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEAD 1447
G C C ++V G C +C+ F + + GC C CN G V C+ +
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFP----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
SG C C+ V GR CD C+PGH+ C C C+ G CD+ T QC+C+ ++
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 1504 RGQACDTCKEEYF 1516
G+ C+ + YF
Sbjct: 548 VGRRCEQVQPGYF 560
Score = 115 bits (276), Expect = 4e-24
Identities = 80/278 (28%), Positives = 118/278 (42%), Gaps = 57/278 (20%)
Query: 358 CQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCT 407
C P P + G G C C+ + +C C Y D P C+ C
Sbjct: 292 CAPAPGAPAHAEGMVH---GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCE 348
Query: 408 CNLNGTEGEHC---------TPTDGLCP-CKYNYAGKSCEICEDGYYSPE---------C 448
C+ T H + G+C C++N AG+ CE+C +Y C
Sbjct: 349 CH-GHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVC 407
Query: 449 KNCECNTVGSVSYV-CDK--------LTGDCTCKSKYSGRTCNQCQAGYYNYPT-----C 494
++C+C+ +GS CD ++G C CK G C QC+ G++ C
Sbjct: 408 RSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGC 467
Query: 495 KPCNCDTSGTEPSI--CDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRERQCVPCN 549
+ C C+ GT P CD SG C CK G CD+CL G++ +LG C PC+
Sbjct: 468 RRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG----CRPCD 523
Query: 550 CDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYK 586
CD G+ C G+C+C + G +C+Q PGY++
Sbjct: 524 CDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
Score = 112 bits (270), Expect = 2e-23
Identities = 68/210 (32%), Positives = 86/210 (40%), Gaps = 18/210 (8%)
Query: 1339 PCLCDFMGSTELEC--NTFGGQCP-CKPNVIGR----TCSACRTGYYGFPNCRPCHCPST 1391
P CD L C +T G C CKP G+ +C C G N + C P
Sbjct: 997 PDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLG-TNPQQCPSPDQ 1055
Query: 1392 AICD-DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGK 1450
CD +G C C NV+G +CDRC P +N GC C C+P G C +G+
Sbjct: 1056 CHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGP--TCNEFTGQ 1113
Query: 1451 CACRENVRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C CR GR C C H+ P C+ C C+ G C + T C C+ V G C
Sbjct: 1114 CHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRC 1173
Query: 1509 DTCKEEYFNLQDDNPDGCTKCF-CFGKTTR 1537
D C + + C C CFG R
Sbjct: 1174 DQCARAFSGIF----PACHPCHACFGDWDR 1199
Score = 112 bits (269), Expect = 3e-23
Identities = 91/261 (34%), Positives = 114/261 (43%), Gaps = 45/261 (17%)
Query: 1825 NFALSCDLSENGSLIS--------CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
N AL C + GSL S C C+PG G RC+ CA GYYG TG C+
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP-----TG--CQA 830
Query: 1877 CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG 1936
C CS C+ +G CL C G C+ C G +G +C C+C+ G
Sbjct: 831 CQCSH--EGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCN--G 881
Query: 1937 MAD-CDSTTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC--GIASE---ST 1986
AD C++ TG C+ CR GE C+RC G L G C PC C G S+ +T
Sbjct: 882 HADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFAT 941
Query: 1987 QCDDDNGQ----CRCAKGVTGKQCDQCAAG-FWNYTKDG--CDHCNC--NTGYSVGFMCN 2037
C D C C G TG +C+ CA G F + ++ G C C C N C+
Sbjct: 942 SCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACD 1001
Query: 2038 A-TGQC-ECLPGVIGEKCDRC 2056
TGQC CL G C C
Sbjct: 1002 PHTGQCLRCLHHTEGPHCAHC 1022
Score = 103 bits (248), Expect = 9e-21
Identities = 70/220 (31%), Positives = 92/220 (41%), Gaps = 28/220 (12%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI- 1393
+G + C C G+ C GQC C+ G C C+ G +GFP+CRPC C A
Sbjct: 826 TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADE 885
Query: 1394 CDDN-GMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQ----LQ 1443
C+ + G C+ C + GE+C+RC F+ D + C C C P G G+Q
Sbjct: 886 CNTHTGACLGCRDHTGGEHCERCIA-GFHGDPRLPYGGQCRPCPC-PEGP-GSQRHFATS 942
Query: 1444 CEADSGK----CACRENVRGRVCDHCVPGHYAFPD-----CYQCTC--NRHGTTYDVCDQ 1492
C D C CR G C+ C PGH+ P C C C N D CD
Sbjct: 943 CHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDP 1002
Query: 1493 NTAQCY-CKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+T QC C + G C CK + C +C C
Sbjct: 1003 HTGQCLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTC 1040
Score = 99.1 bits (236), Expect = 3e-19
Identities = 53/150 (35%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Query: 1913 CAPGFYG-DAIFSKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
CAP + C C+ G ++C+ G C+C+PGV+G +CD CAP ++G
Sbjct: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFG 824
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC C C + S+ C+ +GQC C G G +CD+C G W + C C CN
Sbjct: 825 P-TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPCVCN- 880
Query: 2029 GYSVGFMCNA-TGQC-ECLPGVIGEKCDRC 2056
G++ CN TG C C GE C+RC
Sbjct: 881 GHA--DECNTHTGACLGCRDHTGGEHCERC 908
Score = 98.7 bits (235), Expect = 3e-19
Identities = 67/232 (28%), Positives = 92/232 (39%), Gaps = 29/232 (12%)
Query: 228 GGRCM---CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
GGRC C+G+ D +P D RC H+T GP C C GF +
Sbjct: 980 GGRCQLCECSGNIDPMDP-DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-------A 1031
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
R SC C C+ T P D+ G+C C N +G +C++C P +
Sbjct: 1032 RQSCHRCTCNLLGTNPQQCPSPDQCHCD-------PSSGQC-PCLPNVQGPSCDRCAPNF 1083
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAYGYFDYP-- 401
+ CQPC C P + G C E +G+C CR F CS C ++ P
Sbjct: 1084 WNLTSGHG-----CQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGL 1138
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--PECKNC 451
C C C+ G + C G C C+ +G C+ C + P C C
Sbjct: 1139 QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARAFSGIFPACHPC 1190
Score = 92.7 bits (220), Expect = 2e-17
Identities = 65/218 (29%), Positives = 86/218 (39%), Gaps = 44/218 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPS-TAICD---------- 1395
G C CK N G C C+ Y P CR C C T C
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNFDVQ-----RGCDDCNCNPLGVV-GNQLQCEA 1446
G+C C N G +C+ C+P+ + + C C+C+P+G G +
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 1447 D------SGKCACRENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTT--YDVCDQN 1493
D SG+C C+E+V G C C G + C +C CN GT CD N
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 1494 TAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ CYCK V G+ CD C ++ L D GC C C
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLL-GCRPCDC 524
Score = 88.2 bits (209), Expect = 5e-16
Identities = 40/102 (39%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
Query: 1959 DRCAPDHWGLNTGL--GCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN 2015
+ CAP L+T + G PC C S S++C+ GQC C GV G++CD CA G++
Sbjct: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYG 822
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNAT-GQCECLPGVIGEKCDRC 2056
+ GC C C+ ++ +C T GQC C G G +CDRC
Sbjct: 823 FGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRC 864
Score = 86.6 bits (205), Expect = 1e-15
Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 675 CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYR 734
C PL +L G C CN G+L+S CN GQC+CK V R+CD C G+Y
Sbjct: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSS--ECNPHGGQCLCKPGVVGRRCDLCAPGYYG 822
Query: 735 LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPT 787
GC C C G++ + C+KT+GQC C + G RCD+ R + FP+
Sbjct: 823 FGPT---GCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS 873
Score = 84.2 bits (199), Expect = 8e-15
Identities = 63/238 (26%), Positives = 89/238 (37%), Gaps = 51/238 (21%)
Query: 1333 YNSGARPCLC-DFMGS-----TELECNTFGGQ--CPCKPNVIGRTCSACRTGYYGFPNCR 1384
Y RPC C + GS T + + Q C C+ G C AC G++G P+
Sbjct: 920 YGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRP 979
Query: 1385 PCHCPSTAICDDNGMCICPKNV----------------------EGENCDRCKPYTFNFD 1422
C +C C N+ EG +C CKP
Sbjct: 980 GGRCQ---------LCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA 1030
Query: 1423 VQRGCDDCNCNPLGV------VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-- 1474
++ C C CN LG +Q C+ SG+C C NV+G CD C P +
Sbjct: 1031 ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGH 1090
Query: 1475 -CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C C+ C++ T QC+C+ G+ C C+E ++ D C C C
Sbjct: 1091 GCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWG---DPGLQCHACDC 1145
Score = 74.9 bits (176), Expect = 5e-12
Identities = 73/243 (30%), Positives = 99/243 (40%), Gaps = 49/243 (20%)
Query: 1877 CNCSGNIN-----PQDPGSCDS-INGDCLKCVNNTAGAACNLCAPGFYGDAIF------- 1923
C C G+ + P P + ++G C+ C +NT G C C FY D +
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340
Query: 1924 SKNCTACICD------EFGMA----DCDSTTGTCV-CRPGVIGEKCDRCAPDHW-----G 1967
S C C C F MA + + G C C+ G C+ C P +
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 1968 LNTGLGCTPCNCGI--ASESTQCD--DD------NGQCRCAKGVTGKQCDQCAAGFWNYT 2017
L C C+C + + +CD DD +GQCRC + V G +C QC GF+ +
Sbjct: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLS 460
Query: 2018 ---KDGCDHCNCNTGYSV--GFMCNA-TGQCECLPGVIGEKCDRC-PERWVLIPQ-EGCL 2069
+ GC C CN +V C+ +G C C V G CDRC P W L GC
Sbjct: 461 ISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR 520
Query: 2070 ECD 2072
CD
Sbjct: 521 PCD 523
Score = 68.1 bits (159), Expect = 6e-10
Identities = 39/117 (33%), Positives = 53/117 (45%), Gaps = 10/117 (8%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C +++TS + G +PC C + CN F GQC C+ GRTCS C+ ++G P
Sbjct: 1079 CAPNFWNLTSGH--GCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDP 1136
Query: 1382 --NCRPCHCPSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
C C C S I C G C C V G CD+C + ++ F C C
Sbjct: 1137 GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARAFSGIFPACHPCHAC 1193
Score = 65.3 bits (152), Expect = 4e-09
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 11/109 (10%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
CR+ F ++ G R C C+ G+ C+ G C CK V GR C C G++G
Sbjct: 452 CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Query: 1380 FPN----CRPCHCPSTAI----CDD-NGMCICPKNVEGENCDRCKPYTF 1419
+ CRPC C CD+ G C C +++ G C++ +P F
Sbjct: 512 LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 62.1 bits (144), Expect = 4e-08
Identities = 52/192 (27%), Positives = 76/192 (39%), Gaps = 33/192 (17%)
Query: 1378 YGFPN-CRPCH-CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN--CN 1433
YG + C P P+ A +G CIC N G NC++C+ + + + D + C
Sbjct: 286 YGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACR 345
Query: 1434 PLGVVGNQLQCEAD-----------SGKC-ACRENVRGRVCDHCVPGHYAFPD------- 1474
G+ C D G C C+ N GR C+ C P Y P
Sbjct: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPA 405
Query: 1475 -CYQCTCNRHGTTYDV-CDQN--------TAQCYCKTNVRGQACDTCKEEYFNLQDDNPD 1524
C C C+ G+ CD + + QC CK +V G C C++ +F L +
Sbjct: 406 VCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRL 465
Query: 1525 GCTKCFCFGKTT 1536
GC +C C + T
Sbjct: 466 GCRRCQCNARGT 477
Score = 52.4 bits (120), Expect = 3e-05
Identities = 38/134 (28%), Positives = 51/134 (38%), Gaps = 18/134 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSG---FCVPCQCNGH-----SDQCDVNTGICLNCAD 1786
+C+C G C+QC +G + L C CQCN S CD N+G C C
Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCY-CKR 495
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C+ C+ G+ G C C C + CD C+C+
Sbjct: 496 LVTGRGCDRCLPGHWG--LSHDLLGCRPCDCDV---GGALDPQCDEGTG----QCHCRQH 546
Query: 1847 YGGARCEYCAAGYY 1860
G RCE GY+
Sbjct: 547 MVGRRCEQVQPGYF 560
Score = 47.2 bits (107), Expect = 0.001
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 2019 DGCDHCNCNTGYSVGFMCNATG-QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
+G C CN S+ CN G QC C PGV+G +CD C + GC C +
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEG 837
Query: 2078 LIFSV 2082
+ S+
Sbjct: 838 ALSSL 842
Score = 41.5 bits (93), Expect = 0.056
Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 33/163 (20%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGL-------NTGLGCTPCNCGIASESTQCDD------- 1990
G C+C+ G C++C + L C C C + S D
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 1991 --DNGQCR-CAKGVTGKQCDQCAAGFW-NYTKD-----GCDHCNCNT-GYSVGFMCNA-- 2038
G C C G+ C+ C F+ + TKD C C+C+ G G C++
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 2039 -------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+GQC C V+G +C +C + + + L C C
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRC 470
Score = 41.5 bits (93), Expect = 0.056
Identities = 20/59 (33%), Positives = 26/59 (44%)
Query: 726 DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
+ C L T G C C+ GS+ + C+ GQC C V GRRCD +Y
Sbjct: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYY 821
Score = 40.7 bits (91), Expect = 0.097
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 5/47 (10%)
Query: 1497 CYCKTNVRGQACDTCKEEYFNL-----QDDNPDGCTKCFCFGKTTRC 1538
C CK N RG C+ C++ Y +L +D + C KC C G T C
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSC 356
>Z68155-1|CAA92279.1| 1798|Homo sapiens laminin beta 2 chain protein.
Length = 1798
Score = 300 bits (737), Expect = 5e-80
Identities = 142/366 (38%), Positives = 191/366 (52%), Gaps = 21/366 (5%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C GL C++C G + PS C PC CNGH+D+C+ +TG CL C D+T G+HCE
Sbjct: 849 QCLCRTGAFGLRCDRCQRGQWGFPS--CRPCVCNGHADECNTHTGACLGCRDHTGGEHCE 906
Query: 1795 FCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++G+H D + C C CP P +FA SC E I C+C+ GY G RCE
Sbjct: 907 RCIAGFHRDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCE 966
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA G++G P G C+ C CSGNI+P DP +CD G CL+C+++T G C C
Sbjct: 967 ACAPGHFGDPS----RPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHC 1022
Query: 1914 APGFYGDAIFSKNCTACICDEFG----------MADCDSTTGTCVCRPGVIGEKCDRCAP 1963
PGF+G A ++C C C+ G CD ++G C C P V G CDRCAP
Sbjct: 1023 KPGFHGQAA-RQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAP 1081
Query: 1964 DHWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+ W L +G GC PC C + + C++ GQC C G G+ C +C W C
Sbjct: 1082 NFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCH 1141
Query: 2023 HCNCNT-GYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFS 2081
C+C++ G TG C C PGV G +CD+C + I C C +C
Sbjct: 1142 ACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGI-FPACHPCHACFGDWDRV 1200
Query: 2082 VEDLSA 2087
V+DL+A
Sbjct: 1201 VQDLAA 1206
Score = 257 bits (630), Expect = 5e-67
Identities = 149/467 (31%), Positives = 223/467 (47%), Gaps = 48/467 (10%)
Query: 50 YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDY 109
+A R WWQS G+ V + +DL EFH ++ + + RP ++E+S D+
Sbjct: 115 FAPQRRAAWWQS---ENGIP--AVTIQLDLEAEFHFTHLIMTF-KTFRPAAMLVERSADF 168
Query: 110 GKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR 169
G+T+ ++YFS DC F L P D V+C + YS+I P +GE+ +L+
Sbjct: 169 GRTWHVYRYFS---YDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPA 225
Query: 170 -PSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIG 228
P + Y SS +Q + TN+R+ L R L +L+ R+ + +Y+Y++ ++ +
Sbjct: 226 IPIPDPY--SSRIQNLLKITNLRVNLTRLHTLGDNLLDPRRE---IREKYYYALYELVVR 280
Query: 229 GRCMCNGHADTCEPAD--PAGNLNIL--VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
G C C GHA C PA PA ++ C C+HNT G C +C + WR +++
Sbjct: 281 GNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGH 340
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
+C C CH HT C +D +++ + GG C CQHNT G +C CRP +
Sbjct: 341 SHACRKCECHGHTHSCHFD-------MAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFF 393
Query: 345 YRPYGKRWDELDVCQPCQCDPHFST--GNCEEE--------SGRCECRPEFQPPDCSSCA 394
YR K + VC+ C CDP S G C+ SG+C C+ C C
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
Query: 395 YGYF-----DYPNCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE 447
G+F D C+ C CN GT C P G C CK G+ C+ C G++
Sbjct: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS 513
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
C+ C+C+ G++ CD+ TG C C+ GR C Q Q GY+
Sbjct: 514 HDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 242 bits (592), Expect = 2e-62
Identities = 139/425 (32%), Positives = 199/425 (46%), Gaps = 48/425 (11%)
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS---PECKNCECNTV 456
Y PC CN G+ C P G C CK G+ C++C GYY C+ C+C+
Sbjct: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHE 836
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC 516
G++S +C+K +G C C++ G C++CQ G + +P+C+PC C+ E C+ +G C
Sbjct: 837 GALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADE---CNTHTGAC 893
Query: 517 I-CKAGFGGPRCDQCLSGYYMQV-LGRERQCVPCNC-DPTGST---STSCSADG-----K 565
+ C+ GG C++C++G++ L QC PC C + GS +TSC D
Sbjct: 894 LGCRDHTGGEHCERCIAGFHRDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIV 953
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPD-----CLSCNCDVSGSIG----STCDDN-GLC-HCK 614
C+C + G +C+ C+PG++ P C C C SG+I CD + G C C
Sbjct: 954 CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCEC--SGNIDPMDPDACDPHTGQCLRCL 1011
Query: 615 SNFDGAKCDTCREQFYNYPA---CEECNCDPRGVT----ASFAGCGSVPAGELCQCKDRV 667
+ +G C C+ F+ A C C C+ G S C P+ C C V
Sbjct: 1012 HHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
QG C+ C P +WNL + GC+ C C+ + CN +GQC C+ G R C +
Sbjct: 1072 QGPSCDRCAPNFWNLT--SGHGCQPCACHPSRARGP--TCNEFTGQCHCRAGFGGRTCSE 1127
Query: 728 CLDGFYRLQTNDV-FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIR--AHY 784
C + L D C CDCD G C + TG C C V G RCDQ R +
Sbjct: 1128 CQE----LHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGI 1183
Query: 785 FPTLH 789
FP H
Sbjct: 1184 FPACH 1188
Score = 194 bits (473), Expect = 5e-48
Identities = 123/412 (29%), Positives = 177/412 (42%), Gaps = 52/412 (12%)
Query: 360 PCQCDPHFS-TGNCEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGE 416
PCQC+P S + C G+C C+P C CA GY+ + C+ C C+ G
Sbjct: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSS 841
Query: 417 HCTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCT-CKS 474
C T G C C+ G C+ C+ G + P C+ C CN G C+ TG C C+
Sbjct: 842 LCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHAD-ECNTHTGACLGCRD 898
Query: 475 KYSGRTCNQCQAGYYNYP------TCKPCNC-DTSGTE---PSIC--DDVSGQ--CICKA 520
G C +C AG++ P C+PC C + G++ + C D+ S Q C C+A
Sbjct: 899 HTGGEHCERCIAGFHRDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQ 576
G+ G RC+ C G++ +C C C + D G+C CL + G
Sbjct: 959 GYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPH 1018
Query: 577 CDQCSPGYY---KYPDCLSCNCDVSGSIGSTCDDNGLCHCK---------SNFDGAKCDT 624
C C PG++ C C C++ G+ C CHC N G CD
Sbjct: 1019 CAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDR 1078
Query: 625 CREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C F+N + C+ C C P A C G+ C C+ GR C++C+ L+W
Sbjct: 1079 CAPNFWNLTSGHGCQPCACHPS--RARGPTCNEF-TGQ-CHCRAGFGGRTCSECQELHWG 1134
Query: 682 LQEYNP-FGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGF 732
+P C C+C+ G C+ +G C C+ V +CDQC GF
Sbjct: 1135 ----DPGLQCHACDCDSRGI--DTPQCHRFTGHCSCRPGVSGVRCDQCARGF 1180
Score = 194 bits (473), Expect = 5e-48
Identities = 119/394 (30%), Positives = 172/394 (43%), Gaps = 56/394 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGRCE 380
GG+CL C+ G C+ C P YY +G CQ CQC + + CE+ SG+C
Sbjct: 799 GGQCL-CKPGVVGRRCDLCAPGYYG-FGPTG-----CQACQCSHEGALSSLCEKTSGQCL 851
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEIC 439
CR C C G + +P+C+PC CN + E C G C C+ + G+ CE C
Sbjct: 852 CRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADE---CNTHTGACLGCRDHTGGEHCERC 908
Query: 440 EDGY-------YSPECKNCEC-NTVGSVSYVCDKLTGD-------CTCKSKYSGRTCNQC 484
G+ Y +C+ C C GS + D C C++ Y+G C C
Sbjct: 909 IAGFHRDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEAC 968
Query: 485 QAGYYNYPT-----CKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYM 536
G++ P+ C+ C C + +P CD +GQC+ C GP C C G++
Sbjct: 969 APGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHG 1028
Query: 537 QVLGRERQCVPCNCDPTGSTSTSC---------SADGKCNCLTNFGGAQCDQCSPGYYKY 587
Q + C C C+ G+ C + G+C CL N G CD+C+P ++
Sbjct: 1029 Q--AARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNL 1086
Query: 588 PD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPA--CEECNCD 641
C C C S + G TC++ G CHC++ F G C C+E + P C C+CD
Sbjct: 1087 TSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCD 1146
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDC 675
RG+ C C C+ V G C+ C
Sbjct: 1147 SRGIDT--PQCHRFTGH--CSCRPGVSGVRCDQC 1176
Score = 171 bits (415), Expect = 5e-41
Identities = 108/345 (31%), Positives = 152/345 (44%), Gaps = 40/345 (11%)
Query: 540 GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------D 589
G +C P P G C C N G C+QC Y P
Sbjct: 287 GHASECAPA---PGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA 343
Query: 590 CLSCNC---------DVSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA----- 634
C C C D++ + S G+C C+ N G C+ CR FY P
Sbjct: 344 CRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRD 403
Query: 635 ---CEECNCDPRGVTASFAGCGSV--PAGEL----CQCKDRVQGRICNDCKPLYWNLQEY 685
C C+CDP G + C S PA L C+CK+ V G C C+ ++ L
Sbjct: 404 PAVCRSCDCDPMG-SQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSIS 462
Query: 686 NPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE 745
+ GC +C CN GT+ C+ SG C CK+ V R CD+CL G + L ++D+ GC
Sbjct: 463 DRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRP 521
Query: 746 CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSGPV 805
CDCD+GG++D CD+ TGQCHC + GRRC+Q ++ P L +E ED Q V
Sbjct: 522 CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRGQVLDV 581
Query: 806 RYR-NSEEVFPEYSWKGYVVFSLLQNEVINIIQITKSSLYRMVLK 849
R + P ++ G+V Q + + K+ Y ++L+
Sbjct: 582 VERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPKAMDYDLLLR 626
Score = 163 bits (397), Expect = 8e-39
Identities = 120/449 (26%), Positives = 172/449 (38%), Gaps = 80/449 (17%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN +P G C C+ G +C+ C G+ + C+
Sbjct: 783 CQCNPQGSLSSECNPHGGQ----CLCKPGVVGRRCDLCAPGY--------YGFGPTGCQA 830
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C +H + + EK G+CL C+ G+ C++C+
Sbjct: 831 CQC-SHEGALS---SLCEKT-----------SGQCL-CRTGAFGLRCDRCQ-------RG 867
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDYP------NC 403
+W C+PC C+ H C +G C CR C C G+ P C
Sbjct: 868 QWG-FPSCRPCVCNGH--ADECNTHTGACLGCRDHTGGEHCERCIAGFHRDPRLPYGGQC 924
Query: 404 KPCTCNLN-GTEGEHCTPTDG-------LCPCKYNYAGKSCEICEDGYYSP------ECK 449
+PC C G++ T +C C+ Y G CE C G++ C+
Sbjct: 925 RPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQ 984
Query: 450 NCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYNY---PTCKPCNCDTSG 503
CEC N CD TG C C G C C+ G++ +C C C+ G
Sbjct: 985 LCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLG 1044
Query: 504 TEPS--------ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGS 555
T P CD SGQC C GP CD+C ++ G C PC C P+ +
Sbjct: 1045 TNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSG--HGCQPCACHPSRA 1102
Query: 556 TSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKYP--DCLSCNCDVSGSIGSTCDD-NGLC 611
+C+ G+C+C FGG C +C ++ P C +C+CD G C G C
Sbjct: 1103 RGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHC 1162
Query: 612 HCKSNFDGAKCDTCREQFYN-YPACEECN 639
C+ G +CD C F +PAC C+
Sbjct: 1163 SCRPGVSGVRCDQCARGFSGIFPACHPCH 1191
Score = 163 bits (397), Expect = 8e-39
Identities = 115/368 (31%), Positives = 138/368 (37%), Gaps = 54/368 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGH---SDQCDVNTGICLNCADNTIGD 1791
+C C G C+ CA G+Y C CQC+ S C+ +G CL C G
Sbjct: 801 QCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCL-CRTGAFGL 859
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C+ C G G + C C C N A C+ L C+ GG
Sbjct: 860 RCDRCQRGQWGFPS------CRPCVC------NGHADECNTHTGACL---GCRDHTGGEH 904
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC----------LKC 1901
CE C AG++ D L G C+PC C P+ PGS C C
Sbjct: 905 CERCIAGFH---RDPRLPYGGQCRPCPC-----PEGPGSQRHFATSCHQDEYSQQIVCHC 956
Query: 1902 VNNTAGAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIG 1955
G C CAPG +GD + C C C D CD TG C+ C G
Sbjct: 957 RAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEG 1016
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ---------CDDDNGQCRCAKGVTGKQC 2006
C C P G C C C + + Q CD +GQC C V G C
Sbjct: 1017 PHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSC 1076
Query: 2007 DQCAAGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIP 2064
D+CA FWN T GC C C+ + G CN TGQC C G G C C E P
Sbjct: 1077 DRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDP 1136
Query: 2065 QEGCLECD 2072
C CD
Sbjct: 1137 GLQCHACD 1144
Score = 147 bits (357), Expect = 6e-34
Identities = 93/282 (32%), Positives = 128/282 (45%), Gaps = 36/282 (12%)
Query: 1765 CQCNGHSDQC-----------DVNTGICLNCADNTIGDHCEFCMSGYHG----DATVGTP 1809
C C GH+ +C + G C+ C NT G +CE C Y A G
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
Query: 1810 RDCLICACPMPYPSNNFALSCDL-SENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTD 1867
C C C S +F ++ L S N S C+ CQ G CE C +Y P D
Sbjct: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK-D 400
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDS--------INGDCLKCVNNTAGAACNLCAPGFYG 1919
L C+ C+C + QD G CDS ++G C +C + G C C GF+G
Sbjct: 401 LRDPAVCRSCDCDP-MGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFG 458
Query: 1920 DAIFSK-NCTACICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG-LG 1973
+I + C C C+ G CD +G+C C+ V G CDRC P HWGL+ LG
Sbjct: 459 LSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
Query: 1974 CTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
C PC+C + QCD+ GQC C + + G++C+Q G++
Sbjct: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 140 bits (338), Expect = 1e-31
Identities = 83/249 (33%), Positives = 115/249 (46%), Gaps = 36/249 (14%)
Query: 1840 SCNCQPGYGGARCEYCAAGYYGIP----EDTDLHTGDYCKPCNCSGNINPQD------PG 1889
+C C+ G CE C Y +P ED H C+ C C G+ +
Sbjct: 309 ACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA---CRKCECHGHTHSCHFDMAVYLA 365
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN----CTACICDEFGMAD---CDS 1942
S + G C C +NTAG C LC P FY D C +C CD G D CDS
Sbjct: 366 SGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDS 425
Query: 1943 --------TTGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC---GIASESTQCD 1989
+G C C+ V+G +C +C +GL+ LGC C C G ST CD
Sbjct: 426 HDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCD 485
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCN-ATGQCECLP 2046
++G C C + VTG+ CD+C G W + D GC C+C+ G ++ C+ TGQC C
Sbjct: 486 PNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQ 545
Query: 2047 GVIGEKCDR 2055
++G +C++
Sbjct: 546 HMVGRRCEQ 554
Score = 137 bits (332), Expect = 6e-31
Identities = 90/284 (31%), Positives = 124/284 (43%), Gaps = 35/284 (12%)
Query: 1273 VWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNETGLCREAMFSITSE 1332
V L VLV+E DA E + R + SP+E C + S+++
Sbjct: 719 VLLPRVLVLEMFSGGDAAALERQAT-FERYQCHEEGLVPSKTSPSEA--CAPLLISLSTL 775
Query: 1333 YNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNCRPCHCPS 1390
+GA PC C+ GS ECN GGQC CKP V+GR C C GYYGF C+ C C
Sbjct: 776 IYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSH 835
Query: 1391 ----TAICD-DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
+++C+ +G C+C G CDRC+ + F C C CN G+ +C
Sbjct: 836 EGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP---SCRPCVCN-----GHADECN 887
Query: 1446 ADSGKC-ACRENVRGRVCDHCVPGHYAFP------DCYQCTC------NRHGTTYDVCDQ 1492
+G C CR++ G C+ C+ G + P C C C RH T D+
Sbjct: 888 THTGACLGCRDHTGGEHCERCIAGFHRDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDE 947
Query: 1493 NTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDG-CTKCFCFG 1533
+ Q C+C+ G C+ C +F P G C C C G
Sbjct: 948 YSQQIVCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSG 990
Score = 130 bits (314), Expect = 9e-29
Identities = 84/260 (32%), Positives = 118/260 (45%), Gaps = 38/260 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC-----------DV 1776
C C RGL+CEQC + + LP S C C+C+GH+ C +V
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
Query: 1777 NTGICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ G+C C NT G HCE C ++ D T + P C C C P S + CD +
Sbjct: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCD-PMGSQDGG-RCDSHD 427
Query: 1835 NGS--LIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS 1890
+ + L+S C C+ G RC+ C G++G+ L C+ C C N PGS
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLG----CRRCQC--NARGTVPGS 481
Query: 1891 --CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CD +G C C G C+ C PG +G + C C CD G D CD TG
Sbjct: 482 TPCDPNSGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQ 540
Query: 1947 CVCRPGVIGEKCDRCAPDHW 1966
C CR ++G +C++ P ++
Sbjct: 541 CHCRQHMVGRRCEQVQPGYF 560
Score = 127 bits (306), Expect = 9e-28
Identities = 86/293 (29%), Positives = 127/293 (43%), Gaps = 55/293 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYR--PY 348
C C+ H +EC P G G C+ C+HNT G+NC +C+ +YR P+
Sbjct: 283 CFCYGHASECAPAPGAPAHA-----EGMVHGA--CI-CKHNTRGLNCEQCQD-FYRDLPW 333
Query: 349 GKRWD-ELDVCQPCQCDPH-----------FSTGNCEEESGRCE-CRPEFQPPDCSSCAY 395
D C+ C+C H ++GN G C+ C+ C C
Sbjct: 334 RPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS--GGVCDGCQHNTAGRHCELCRP 391
Query: 396 GYFDYPN--------CKPCTCNLNGTE-GEHCTPTD--------GLCPCKYNYAGKSCEI 438
++ P C+ C C+ G++ G C D G C CK + G C+
Sbjct: 392 FFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ 451
Query: 439 CEDGYYSPE------CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYN 490
C DG++ C+ C+CN G+V S CD +G C CK +GR C++C G++
Sbjct: 452 CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Query: 491 YPT----CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
C+PC+CD G CD+ +GQC C+ G RC+Q GY+ L
Sbjct: 512 LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFL 564
Score = 122 bits (294), Expect = 2e-26
Identities = 77/253 (30%), Positives = 114/253 (45%), Gaps = 45/253 (17%)
Query: 423 GLCPCKYNYAGKSCEICEDGY-----------YSPECKNCECNTVG-------SVSYVCD 464
G C CK+N G +CE C+D Y +S C+ CEC+ +V
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 465 KLTGD-CT-CKSKYSGRTCNQCQAGYYNYPT--------CKPCNCDTSGTEPS-ICDD-- 511
++G C C+ +GR C C+ +Y PT C+ C+CD G++ CD
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 512 ------VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST--STSCSAD 563
VSGQC CK G RC QC G++ + C C C+ G+ ST C +
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 564 -GKCNCLTNFGGAQCDQCSPGYYKYP----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNF 617
G C C G CD+C PG++ C C+CDV G++ CD+ G CHC+ +
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 618 DGAKCDTCREQFY 630
G +C+ + ++
Sbjct: 548 VGRRCEQVQPGYF 560
Score = 115 bits (277), Expect = 3e-24
Identities = 62/193 (32%), Positives = 85/193 (44%), Gaps = 29/193 (15%)
Query: 1353 NTFGGQCP-CKPNVIGRTCSACRTGYYGFPN--------CRPCHCPSTAI-----CDDN- 1397
N GG C C+ N GR C CR +Y P CR C C CD +
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 1398 --------GMCICPKNVEGENCDRCKPYTFNFDV--QRGCDDCNCNPLGVVGNQLQCEAD 1447
G C C ++V G C +C+ F + + GC C CN G V C+ +
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFP----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
SG C C+ V GR CD C+PGH+ C C C+ G CD+ T QC+C+ ++
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 1504 RGQACDTCKEEYF 1516
G+ C+ + YF
Sbjct: 548 VGRRCEQVQPGYF 560
Score = 115 bits (276), Expect = 4e-24
Identities = 80/278 (28%), Positives = 118/278 (42%), Gaps = 57/278 (20%)
Query: 358 CQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCT 407
C P P + G G C C+ + +C C Y D P C+ C
Sbjct: 292 CAPAPGAPAHAEGMVH---GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCE 348
Query: 408 CNLNGTEGEHC---------TPTDGLCP-CKYNYAGKSCEICEDGYYSPE---------C 448
C+ T H + G+C C++N AG+ CE+C +Y C
Sbjct: 349 CH-GHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVC 407
Query: 449 KNCECNTVGSVSYV-CDK--------LTGDCTCKSKYSGRTCNQCQAGYYNYPT-----C 494
++C+C+ +GS CD ++G C CK G C QC+ G++ C
Sbjct: 408 RSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGC 467
Query: 495 KPCNCDTSGTEPSI--CDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRERQCVPCN 549
+ C C+ GT P CD SG C CK G CD+CL G++ +LG C PC+
Sbjct: 468 RRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG----CRPCD 523
Query: 550 CDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYK 586
CD G+ C G+C+C + G +C+Q PGY++
Sbjct: 524 CDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
Score = 112 bits (269), Expect = 3e-23
Identities = 68/210 (32%), Positives = 86/210 (40%), Gaps = 18/210 (8%)
Query: 1339 PCLCDFMGSTELEC--NTFGGQCP-CKPNVIGR----TCSACRTGYYGFPNCRPCHCPST 1391
P CD L C +T G C CKP G+ +C C G N + C P
Sbjct: 997 PDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLG-TNPQQCPSPDQ 1055
Query: 1392 AICD-DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGK 1450
CD +G C C NV+G +CDRC P +N GC C C+P G C +G+
Sbjct: 1056 CHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGP--TCNEFTGQ 1113
Query: 1451 CACRENVRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C CR GR C C H+ P C+ C C+ G C + T C C+ V G C
Sbjct: 1114 CHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRC 1173
Query: 1509 DTCKEEYFNLQDDNPDGCTKCF-CFGKTTR 1537
D C + + C C CFG R
Sbjct: 1174 DQCARGFSGIF----PACHPCHACFGDWDR 1199
Score = 109 bits (263), Expect = 1e-22
Identities = 92/261 (35%), Positives = 115/261 (44%), Gaps = 45/261 (17%)
Query: 1825 NFALSCDLSENGSLIS--------CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
N AL C + GSL S C C+PG G RC+ CA GYYG TG C+
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP-----TG--CQA 830
Query: 1877 CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG 1936
C CS C+ +G CL C G C+ C G +G +C C+C+ G
Sbjct: 831 CQCSH--EGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCN--G 881
Query: 1937 MAD-CDSTTGTCV-CRPGVIGEKCDRC-APDHWG--LNTGLGCTPCNC--GIASE---ST 1986
AD C++ TG C+ CR GE C+RC A H L G C PC C G S+ +T
Sbjct: 882 HADECNTHTGACLGCRDHTGGEHCERCIAGFHRDPRLPYGGQCRPCPCPEGPGSQRHFAT 941
Query: 1987 QCDDDNGQ----CRCAKGVTGKQCDQCAAG-FWNYTKDG--CDHCNC--NTGYSVGFMCN 2037
C D C C G TG +C+ CA G F + ++ G C C C N C+
Sbjct: 942 SCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACD 1001
Query: 2038 A-TGQC-ECLPGVIGEKCDRC 2056
TGQC CL G C C
Sbjct: 1002 PHTGQCLRCLHHTEGPHCAHC 1022
Score = 103 bits (248), Expect = 9e-21
Identities = 70/220 (31%), Positives = 92/220 (41%), Gaps = 28/220 (12%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI- 1393
+G + C C G+ C GQC C+ G C C+ G +GFP+CRPC C A
Sbjct: 826 TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADE 885
Query: 1394 CDDN-GMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQ----LQ 1443
C+ + G C+ C + GE+C+RC F+ D + C C C P G G+Q
Sbjct: 886 CNTHTGACLGCRDHTGGEHCERCIA-GFHRDPRLPYGGQCRPCPC-PEGP-GSQRHFATS 942
Query: 1444 CEADSGK----CACRENVRGRVCDHCVPGHYAFPD-----CYQCTC--NRHGTTYDVCDQ 1492
C D C CR G C+ C PGH+ P C C C N D CD
Sbjct: 943 CHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDP 1002
Query: 1493 NTAQCY-CKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+T QC C + G C CK + C +C C
Sbjct: 1003 HTGQCLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTC 1040
Score = 101 bits (241), Expect = 6e-20
Identities = 68/232 (29%), Positives = 93/232 (40%), Gaps = 29/232 (12%)
Query: 228 GGRCM---CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
GGRC C+G+ D +P D RC H+T GP C C GF +
Sbjct: 980 GGRCQLCECSGNIDPMDP-DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-------A 1031
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
R SC C C+ T P D+ G+C C N +G +C++C P +
Sbjct: 1032 RQSCHRCTCNLLGTNPQQCPSPDQCHCD-------PSSGQC-PCLPNVQGPSCDRCAPNF 1083
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAYGYFDYP-- 401
+ CQPC C P + G C E +G+C CR F CS C ++ P
Sbjct: 1084 WNLTSGHG-----CQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGL 1138
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS--PECKNC 451
C C C+ G + C G C C+ +G C+ C G+ P C C
Sbjct: 1139 QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPC 1190
Score = 99.1 bits (236), Expect = 3e-19
Identities = 53/150 (35%), Positives = 74/150 (49%), Gaps = 12/150 (8%)
Query: 1913 CAPGFYG-DAIFSKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
CAP + C C+ G ++C+ G C+C+PGV+G +CD CAP ++G
Sbjct: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFG 824
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC C C + S+ C+ +GQC C G G +CD+C G W + C C CN
Sbjct: 825 P-TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPCVCN- 880
Query: 2029 GYSVGFMCNA-TGQC-ECLPGVIGEKCDRC 2056
G++ CN TG C C GE C+RC
Sbjct: 881 GHA--DECNTHTGACLGCRDHTGGEHCERC 908
Score = 92.7 bits (220), Expect = 2e-17
Identities = 65/218 (29%), Positives = 86/218 (39%), Gaps = 44/218 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPS-TAICD---------- 1395
G C CK N G C C+ Y P CR C C T C
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNFDVQ-----RGCDDCNCNPLGVV-GNQLQCEA 1446
G+C C N G +C+ C+P+ + + C C+C+P+G G +
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 1447 D------SGKCACRENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTT--YDVCDQN 1493
D SG+C C+E+V G C C G + C +C CN GT CD N
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 1494 TAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ CYCK V G+ CD C ++ L D GC C C
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLL-GCRPCDC 524
Score = 88.2 bits (209), Expect = 5e-16
Identities = 40/102 (39%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
Query: 1959 DRCAPDHWGLNTGL--GCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN 2015
+ CAP L+T + G PC C S S++C+ GQC C GV G++CD CA G++
Sbjct: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYG 822
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNAT-GQCECLPGVIGEKCDRC 2056
+ GC C C+ ++ +C T GQC C G G +CDRC
Sbjct: 823 FGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRC 864
Score = 86.6 bits (205), Expect = 1e-15
Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 675 CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYR 734
C PL +L G C CN G+L+S CN GQC+CK V R+CD C G+Y
Sbjct: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSS--ECNPHGGQCLCKPGVVGRRCDLCAPGYYG 822
Query: 735 LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPT 787
GC C C G++ + C+KT+GQC C + G RCD+ R + FP+
Sbjct: 823 FGPT---GCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS 873
Score = 84.2 bits (199), Expect = 8e-15
Identities = 63/238 (26%), Positives = 89/238 (37%), Gaps = 51/238 (21%)
Query: 1333 YNSGARPCLC-DFMGS-----TELECNTFGGQ--CPCKPNVIGRTCSACRTGYYGFPNCR 1384
Y RPC C + GS T + + Q C C+ G C AC G++G P+
Sbjct: 920 YGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRP 979
Query: 1385 PCHCPSTAICDDNGMCICPKNV----------------------EGENCDRCKPYTFNFD 1422
C +C C N+ EG +C CKP
Sbjct: 980 GGRCQ---------LCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA 1030
Query: 1423 VQRGCDDCNCNPLGV------VGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD-- 1474
++ C C CN LG +Q C+ SG+C C NV+G CD C P +
Sbjct: 1031 ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGH 1090
Query: 1475 -CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C C C+ C++ T QC+C+ G+ C C+E ++ D C C C
Sbjct: 1091 GCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWG---DPGLQCHACDC 1145
Score = 74.9 bits (176), Expect = 5e-12
Identities = 73/243 (30%), Positives = 99/243 (40%), Gaps = 49/243 (20%)
Query: 1877 CNCSGNIN-----PQDPGSCDS-INGDCLKCVNNTAGAACNLCAPGFYGDAIF------- 1923
C C G+ + P P + ++G C+ C +NT G C C FY D +
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340
Query: 1924 SKNCTACICD------EFGMA----DCDSTTGTCV-CRPGVIGEKCDRCAPDHW-----G 1967
S C C C F MA + + G C C+ G C+ C P +
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 1968 LNTGLGCTPCNCGI--ASESTQCD--DD------NGQCRCAKGVTGKQCDQCAAGFWNYT 2017
L C C+C + + +CD DD +GQCRC + V G +C QC GF+ +
Sbjct: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLS 460
Query: 2018 ---KDGCDHCNCNTGYSV--GFMCNA-TGQCECLPGVIGEKCDRC-PERWVLIPQ-EGCL 2069
+ GC C CN +V C+ +G C C V G CDRC P W L GC
Sbjct: 461 ISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR 520
Query: 2070 ECD 2072
CD
Sbjct: 521 PCD 523
Score = 67.7 bits (158), Expect = 7e-10
Identities = 39/117 (33%), Positives = 53/117 (45%), Gaps = 10/117 (8%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C +++TS + G +PC C + CN F GQC C+ GRTCS C+ ++G P
Sbjct: 1079 CAPNFWNLTSGH--GCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDP 1136
Query: 1382 --NCRPCHCPSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
C C C S I C G C C V G CD+C + ++ F C C
Sbjct: 1137 GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHAC 1193
Score = 65.3 bits (152), Expect = 4e-09
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 11/109 (10%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
CR+ F ++ G R C C+ G+ C+ G C CK V GR C C G++G
Sbjct: 452 CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Query: 1380 FPN----CRPCHCPSTAI----CDD-NGMCICPKNVEGENCDRCKPYTF 1419
+ CRPC C CD+ G C C +++ G C++ +P F
Sbjct: 512 LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 62.1 bits (144), Expect = 4e-08
Identities = 52/192 (27%), Positives = 76/192 (39%), Gaps = 33/192 (17%)
Query: 1378 YGFPN-CRPCH-CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN--CN 1433
YG + C P P+ A +G CIC N G NC++C+ + + + D + C
Sbjct: 286 YGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACR 345
Query: 1434 PLGVVGNQLQCEAD-----------SGKC-ACRENVRGRVCDHCVPGHYAFPD------- 1474
G+ C D G C C+ N GR C+ C P Y P
Sbjct: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPA 405
Query: 1475 -CYQCTCNRHGTTYDV-CDQN--------TAQCYCKTNVRGQACDTCKEEYFNLQDDNPD 1524
C C C+ G+ CD + + QC CK +V G C C++ +F L +
Sbjct: 406 VCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRL 465
Query: 1525 GCTKCFCFGKTT 1536
GC +C C + T
Sbjct: 466 GCRRCQCNARGT 477
Score = 52.4 bits (120), Expect = 3e-05
Identities = 38/134 (28%), Positives = 51/134 (38%), Gaps = 18/134 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSG---FCVPCQCNGH-----SDQCDVNTGICLNCAD 1786
+C+C G C+QC +G + L C CQCN S CD N+G C C
Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCY-CKR 495
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
G C+ C+ G+ G C C C + CD C+C+
Sbjct: 496 LVTGRGCDRCLPGHWG--LSHDLLGCRPCDCDV---GGALDPQCDEGTG----QCHCRQH 546
Query: 1847 YGGARCEYCAAGYY 1860
G RCE GY+
Sbjct: 547 MVGRRCEQVQPGYF 560
Score = 47.2 bits (107), Expect = 0.001
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 2019 DGCDHCNCNTGYSVGFMCNATG-QCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
+G C CN S+ CN G QC C PGV+G +CD C + GC C +
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEG 837
Query: 2078 LIFSV 2082
+ S+
Sbjct: 838 ALSSL 842
Score = 41.5 bits (93), Expect = 0.056
Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 33/163 (20%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGL-------NTGLGCTPCNCGIASESTQCDD------- 1990
G C+C+ G C++C + L C C C + S D
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 1991 --DNGQCR-CAKGVTGKQCDQCAAGFW-NYTKD-----GCDHCNCNT-GYSVGFMCNA-- 2038
G C C G+ C+ C F+ + TKD C C+C+ G G C++
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 2039 -------TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+GQC C V+G +C +C + + + L C C
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRC 470
Score = 41.5 bits (93), Expect = 0.056
Identities = 20/59 (33%), Positives = 26/59 (44%)
Query: 726 DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
+ C L T G C C+ GS+ + C+ GQC C V GRRCD +Y
Sbjct: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYY 821
Score = 40.7 bits (91), Expect = 0.097
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 5/47 (10%)
Query: 1497 CYCKTNVRGQACDTCKEEYFNL-----QDDNPDGCTKCFCFGKTTRC 1538
C CK N RG C+ C++ Y +L +D + C KC C G T C
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSC 356
>Z15009-1|CAA78729.1| 1111|Homo sapiens Laminin protein.
Length = 1111
Score = 293 bits (720), Expect = 6e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-IPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (305), Expect = 1e-27
Identities = 77/230 (33%), Positives = 107/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVIPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCECNT--VGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+CN+ S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 123 bits (297), Expect = 1e-26
Identities = 77/236 (32%), Positives = 99/236 (41%), Gaps = 30/236 (12%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSG 533
C C G+YN P +CKPC C + I + C C G G RC+ C G
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCADG 499
Query: 534 YYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYYK 586
Y+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 500 YFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
Query: 587 YP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 560 DPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (289), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 111 bits (267), Expect = 5e-23
Identities = 73/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ S +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCN-SNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 98.3 bits (234), Expect = 5e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.1 bits (216), Expect = 7e-17
Identities = 59/175 (33%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLTDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.8 bits (213), Expect = 2e-16
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.8 bits (213), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVIPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 88.6 bits (210), Expect = 4e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF T GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 84.6 bits (200), Expect = 6e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 81.4 bits (192), Expect = 6e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L D GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHML--TDA-GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 72.9 bits (171), Expect = 2e-11
Identities = 52/160 (32%), Positives = 67/160 (41%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 PS------TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
S + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LTDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 70.9 bits (166), Expect = 8e-11
Identities = 59/198 (29%), Positives = 74/198 (37%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ G + + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCHN-GFSCSVIP-ETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 66.1 bits (154), Expect = 2e-09
Identities = 44/154 (28%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+++ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNSNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 65.7 bits (153), Expect = 3e-09
Identities = 38/120 (31%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S + C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVIP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.0 bits (124), Expect = 1e-05
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>Z15008-1|CAA78728.1| 1193|Homo sapiens Laminin protein.
Length = 1193
Score = 293 bits (720), Expect = 6e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-IPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (305), Expect = 1e-27
Identities = 77/230 (33%), Positives = 107/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVIPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCECNT--VGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+CN+ S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 123 bits (297), Expect = 1e-26
Identities = 77/236 (32%), Positives = 99/236 (41%), Gaps = 30/236 (12%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSG 533
C C G+YN P +CKPC C + I + C C G G RC+ C G
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCADG 499
Query: 534 YYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYYK 586
Y+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 500 YFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
Query: 587 YP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 560 DPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (289), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 111 bits (267), Expect = 5e-23
Identities = 73/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ S +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCN-SNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 98.3 bits (234), Expect = 5e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.1 bits (216), Expect = 7e-17
Identities = 59/175 (33%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLTDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.8 bits (213), Expect = 2e-16
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.8 bits (213), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVIPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 88.6 bits (210), Expect = 4e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF T GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 84.6 bits (200), Expect = 6e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 81.4 bits (192), Expect = 6e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L D GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHML--TDA-GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 72.9 bits (171), Expect = 2e-11
Identities = 52/160 (32%), Positives = 67/160 (41%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 PS------TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
S + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LTDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 70.9 bits (166), Expect = 8e-11
Identities = 59/198 (29%), Positives = 74/198 (37%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ G + + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCHN-GFSCSVIP-ETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 66.1 bits (154), Expect = 2e-09
Identities = 44/154 (28%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+++ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNSNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 65.7 bits (153), Expect = 3e-09
Identities = 38/120 (31%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S + C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVIP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.0 bits (124), Expect = 1e-05
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>X73902-1|CAA52108.1| 1193|Homo sapiens nicein protein.
Length = 1193
Score = 293 bits (720), Expect = 6e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (304), Expect = 2e-27
Identities = 77/230 (33%), Positives = 106/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+C N S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 122 bits (294), Expect = 2e-26
Identities = 77/237 (32%), Positives = 100/237 (42%), Gaps = 32/237 (13%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI--CKAGFGGPRCDQCLS 532
C C G+YN P +CKPC C +G S+ + C G G RC+ C
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Query: 533 GYYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYY 585
GY+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 586 KYP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (288), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 109 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ + +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 98.3 bits (234), Expect = 5e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.1 bits (216), Expect = 7e-17
Identities = 59/175 (33%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLTDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.8 bits (213), Expect = 2e-16
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.8 bits (213), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF T GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 84.6 bits (200), Expect = 6e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 81.4 bits (192), Expect = 6e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L D GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHML--TDA-GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 -----PS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
PS + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 72.1 bits (169), Expect = 3e-11
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LTDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 68.1 bits (159), Expect = 6e-10
Identities = 45/154 (29%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+N+ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNNNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 67.3 bits (157), Expect = 1e-09
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S M C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.4 bits (125), Expect = 7e-06
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>U31201-1|AAC50457.1| 1193|Homo sapiens laminin gamma2 chain protein.
Length = 1193
Score = 293 bits (720), Expect = 6e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (304), Expect = 2e-27
Identities = 77/230 (33%), Positives = 106/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+C N S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 122 bits (294), Expect = 2e-26
Identities = 77/237 (32%), Positives = 100/237 (42%), Gaps = 32/237 (13%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI--CKAGFGGPRCDQCLS 532
C C G+YN P +CKPC C +G S+ + C G G RC+ C
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Query: 533 GYYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYY 585
GY+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 586 KYP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (288), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 109 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ + +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 98.3 bits (234), Expect = 5e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.1 bits (216), Expect = 7e-17
Identities = 59/175 (33%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLTDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.8 bits (213), Expect = 2e-16
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.8 bits (213), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF T GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 84.6 bits (200), Expect = 6e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 81.4 bits (192), Expect = 6e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L D GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHML--TDA-GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 -----PS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
PS + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 72.1 bits (169), Expect = 3e-11
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LTDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 68.1 bits (159), Expect = 6e-10
Identities = 45/154 (29%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+N+ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNNNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 67.3 bits (157), Expect = 1e-09
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S M C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.4 bits (125), Expect = 7e-06
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>U31200-1|AAC50456.1| 1111|Homo sapiens alternatively spliced laminin
gamma2 chain protein.
Length = 1111
Score = 293 bits (720), Expect = 6e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (304), Expect = 2e-27
Identities = 77/230 (33%), Positives = 106/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+C N S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 122 bits (294), Expect = 2e-26
Identities = 77/237 (32%), Positives = 100/237 (42%), Gaps = 32/237 (13%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI--CKAGFGGPRCDQCLS 532
C C G+YN P +CKPC C +G S+ + C G G RC+ C
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Query: 533 GYYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYY 585
GY+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 586 KYP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (288), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 109 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ + +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 98.3 bits (234), Expect = 5e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.1 bits (216), Expect = 7e-17
Identities = 59/175 (33%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLTDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.8 bits (213), Expect = 2e-16
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.8 bits (213), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF T GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 84.6 bits (200), Expect = 6e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 81.4 bits (192), Expect = 6e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L D GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHML--TDA-GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 -----PS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
PS + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 72.1 bits (169), Expect = 3e-11
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LTDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 68.1 bits (159), Expect = 6e-10
Identities = 45/154 (29%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+N+ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNNNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 67.3 bits (157), Expect = 1e-09
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S M C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.4 bits (125), Expect = 7e-06
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>BC113378-1|AAI13379.1| 1111|Homo sapiens laminin, gamma 2 protein.
Length = 1111
Score = 293 bits (720), Expect = 6e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (304), Expect = 2e-27
Identities = 77/230 (33%), Positives = 106/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+C N S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 122 bits (294), Expect = 2e-26
Identities = 77/237 (32%), Positives = 100/237 (42%), Gaps = 32/237 (13%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI--CKAGFGGPRCDQCLS 532
C C G+YN P +CKPC C +G S+ + C G G RC+ C
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Query: 533 GYYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYY 585
GY+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 586 KYP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (288), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 109 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ + +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 98.3 bits (234), Expect = 5e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.1 bits (216), Expect = 7e-17
Identities = 59/175 (33%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLTDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.8 bits (213), Expect = 2e-16
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.8 bits (213), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF T GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 84.6 bits (200), Expect = 6e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 81.4 bits (192), Expect = 6e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L D GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHML--TDA-GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 -----PS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
PS + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 72.1 bits (169), Expect = 3e-11
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LTDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 68.1 bits (159), Expect = 6e-10
Identities = 45/154 (29%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+N+ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNNNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 67.3 bits (157), Expect = 1e-09
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S M C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.4 bits (125), Expect = 7e-06
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>AL354953-2|CAH70980.1| 1193|Homo sapiens laminin, gamma 2 protein.
Length = 1193
Score = 293 bits (720), Expect = 6e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (304), Expect = 2e-27
Identities = 77/230 (33%), Positives = 106/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+C N S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 122 bits (294), Expect = 2e-26
Identities = 77/237 (32%), Positives = 100/237 (42%), Gaps = 32/237 (13%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI--CKAGFGGPRCDQCLS 532
C C G+YN P +CKPC C +G S+ + C G G RC+ C
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Query: 533 GYYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYY 585
GY+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 586 KYP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (288), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 109 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ + +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 98.3 bits (234), Expect = 5e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.1 bits (216), Expect = 7e-17
Identities = 59/175 (33%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLTDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.8 bits (213), Expect = 2e-16
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.8 bits (213), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF T GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 84.6 bits (200), Expect = 6e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 81.4 bits (192), Expect = 6e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L D GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHML--TDA-GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 -----PS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
PS + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 72.1 bits (169), Expect = 3e-11
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LTDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 68.1 bits (159), Expect = 6e-10
Identities = 45/154 (29%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+N+ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNNNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 67.3 bits (157), Expect = 1e-09
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S M C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.4 bits (125), Expect = 7e-06
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>BC112286-1|AAI12287.1| 1111|Homo sapiens laminin, gamma 2 protein.
Length = 1111
Score = 293 bits (719), Expect = 8e-78
Identities = 192/591 (32%), Positives = 279/591 (47%), Gaps = 58/591 (9%)
Query: 1397 NGM-CI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
NG C+ C N +G +C++CK + + C CNCN G + +C+ +SG+C+C+
Sbjct: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCD-NSGRCSCK 105
Query: 1455 ENVRGRVCDHCVPGHYAFPD--CYQ--------CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
V G CD C+PG + D C Q C C+ G CD +C CK V
Sbjct: 106 PGVTGARCDRCLPGFHMLMDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVT 162
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVDVLINNT 1564
G+ CD C+ Y+NL NP+GCT+CFC+G + C SS ++ ++ + DV +
Sbjct: 163 GERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSS--AEYSVHKITSTFHQDV---DG 217
Query: 1565 IELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTVHYTT 1624
+ P + + YF AP +LG + SYG L++ Y
Sbjct: 218 WKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--YRV 275
Query: 1625 RGDGDAVAAPDVIIAGPNGYLVHNSV---EQPPVGMPWTHSVKLSEEEFSTLDGAPVTRD 1681
G +A DVI+ G + + + P G+ T++ +L+E + ++
Sbjct: 276 DRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWS-PQLSYF 334
Query: 1682 QFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRA 1741
++ L N++ L IRA+Y EYS + NV L I G A VE+C CP
Sbjct: 335 EYRRLLRNLTALRIRATYGEYSTGY-IDNVTL-ISARPVSGAP-----APWVEQCICPVG 387
Query: 1742 YRGLSCEQCAEGHYRL-----PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
Y+G C+ CA G+ R P G C+PC C G CD +TG C + D C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADC 445
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G++ D PR C C C N F+ S + E ++ NC PG GARCE CA
Sbjct: 446 PIGFYNDPH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCA 497
Query: 1857 AGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPG 1916
GY+G P C+PC C+ N++P G+CD + G CLKC++NTAG C+ C G
Sbjct: 498 DGYFGDPFGEHGPVRP-CQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 1917 FYGDAIF---SKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCA 1962
++GD + + C AC C+ G C S GTCVC+PG G C+ A
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 126 bits (304), Expect = 2e-27
Identities = 77/230 (33%), Positives = 106/230 (46%), Gaps = 32/230 (13%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+C+ C +G C C Y R R C PC C G C+ ++G C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQ---GGGACDPDTGDCYSGD 435
Query: 384 EFQPPDCSSCAYGYFDYP----NCKPCTCNLNGTEGEHCTPTDG-LC-PCKYNYAGKSCE 437
E +C+ C G+++ P +CKPC C+ NG T+ +C C G CE
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCE 494
Query: 438 ICEDGYYSP---------ECKNCEC--NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQ 485
+C DGY+ C+ C+C N S S CD+LTG C C +G C+QC+
Sbjct: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 486 AGYYNYP-------TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
AGY+ P C+ CNC+ G+EP C G C+CK GFGGP C+
Sbjct: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCE 603
Score = 122 bits (294), Expect = 2e-26
Identities = 77/237 (32%), Positives = 100/237 (42%), Gaps = 32/237 (13%)
Query: 425 CPCKYNYAGKSCEICEDGYYSPECK-----NC-ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
C C Y G+ C+ C GY + C CN G + CD TGDC +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA--CDPDTGDCYSGDENPD 439
Query: 479 RTCNQCQAGYYNYP----TCKPCNCDTSGTEPSICDDVSGQCI--CKAGFGGPRCDQCLS 532
C C G+YN P +CKPC C +G S+ + C G G RC+ C
Sbjct: 440 IECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Query: 533 GYYMQVLGRE---RQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQCDQCSPGYY 585
GY+ G R C PC C+ S S + D G+C C+ N G CDQC GY+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 586 KYP-------DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
P C +CNC+ GS C +G C CK F G C+ ++ PAC
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 120 bits (288), Expect = 1e-25
Identities = 78/231 (33%), Positives = 94/231 (40%), Gaps = 26/231 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C GY G C+ CA+GY + L C PCNC G G+CD GDC
Sbjct: 382 CICPVGYKGQFCQDCASGYKR--DSARLGPFGTCIPCNCQGG------GACDPDTGDCYS 433
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR---PGVIGEK 1957
N C C GFY D ++C C C T VC PGV G +
Sbjct: 434 GDENP-DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 1958 CDRCAPDHWGLNTG-----LGCTPCNCGI---ASESTQCDDDNGQC-RCAKGVTGKQCDQ 2008
C+ CA ++G G C PC C S S CD G+C +C G CDQ
Sbjct: 493 CELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
Query: 2009 CAAGFWN-----YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C AG++ D C CNCN S C + G C C PG G C+
Sbjct: 553 CKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 109 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 35/240 (14%)
Query: 378 RCECRPEFQPPDCSSCAYGYF-------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+C C ++ C CA GY + C PC C G C P G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 431 YAGKSCEICEDGYYSP-----ECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQC 484
C C G+Y+ CK C C+ S S + + C C +G C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 485 QAGYYNYP--------TCKPCNCDTSGTEPSI---CDDVSGQCI-CKAGFGGPRCDQCLS 532
GY+ P C+PC C+ + +PS CD ++G+C+ C G CDQC +
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 533 GYYMQVLGRER--QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
GY+ L +C CNC+P GS C +DG C C FGG C+ G + P C
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
Score = 97.9 bits (233), Expect = 6e-19
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Query: 515 QCI-CKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
+C+ C G C++C +G+Y RER +C+PCNC+ GS S C G+C+C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRH---RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
Query: 573 GGAQCDQCSPGYYKYPD--CL--------SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
GA+CD+C PG++ D C C+CD +G I C D G C CK G +C
Sbjct: 109 TGARCDRCLPGFHMLMDAGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERC 166
Query: 623 DTCREQFYNY-----PACEECNC 640
D CR +YN C +C C
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.3 bits (224), Expect = 7e-18
Identities = 67/231 (29%), Positives = 94/231 (40%), Gaps = 27/231 (11%)
Query: 515 QCICKAGFGGPRCDQCLSGYYMQV--LGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTN 571
QCIC G+ G C C SGY LG C+PCNC G+ C D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 572 FGGAQCDQCSPGYYKYP----DCLSCNCD--VSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+C C G+Y P C C C S S+ ++ +C GA+C+ C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 626 REQFYNYP--------ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKP 677
+ ++ P C+ C C+ ++ C + G +C G C+ CK
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL-TGRCLKCIHNTAGIYCDQCKA 555
Query: 678 LYW-NLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
Y+ + NP C CNCN G+ +G C + G CVCK G C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGS-EPVG-CRS-DGTCVCKPGFGGPNCE 603
Score = 91.5 bits (217), Expect = 5e-17
Identities = 59/175 (33%), Positives = 79/175 (45%), Gaps = 32/175 (18%)
Query: 1334 NSGARPCLCDFMGSTELECNTFGG-QC-PCKPNVIGRTCSACRTGYYGF---PNCRPCHC 1388
N +R C+ D EL T G +C C N G C C+ G+Y C PC+C
Sbjct: 31 NGKSRQCIFD----RELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1389 PS----TAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC--------DDCNCNPLG 1436
S +A CD++G C C V G CDRC P F+ + GC C+C+P G
Sbjct: 87 NSKGSLSARCDNSGRCSCKPGVTGARCDRCLP-GFHMLMDAGCTQDQRLLDSKCDCDPAG 145
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF----PD-CYQCTCNRHGTT 1486
+ G D+G+C C+ V G CD C G+Y P+ C QC C H +
Sbjct: 146 IAG-----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Score = 90.6 bits (215), Expect = 9e-17
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 26/158 (16%)
Query: 1834 ENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
+ G+ C NC G CE C G+Y E D C PCNC N CD
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER------DRCLPCNC--NSKGSLSARCD 97
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA--------CICDEFGMAD-CDST 1943
+ +G C C GA C+ C PGF+ + CT C CD G+A CD+
Sbjct: 98 N-SGRC-SCKPGVTGARCDRCLPGFH--MLMDAGCTQDQRLLDSKCDCDPAGIAGPCDA- 152
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC 1979
G CVC+P V GE+CDRC ++ L+ G GCT C C
Sbjct: 153 -GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 90.2 bits (214), Expect = 1e-16
Identities = 61/201 (30%), Positives = 85/201 (42%), Gaps = 35/201 (17%)
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGG-KCLNCQHNTEGINCNKCRPTYYRP 347
E C+C+ + +C +D E+ R G G +CLNC NT+GI+C KC+ +Y
Sbjct: 26 EVCDCNGKSRQCIFDRELH----------RQTGNGFRCLNCNDNTDGIHCEKCKNGFY-- 73
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC---- 403
R E D C PC C+ S + SGRC C+P C C G+ +
Sbjct: 74 ---RHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLMDAGCTQ 130
Query: 404 ------KPCTCNLNGTEGEHCTPTD-GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
C C+ G G P D G C CK G+ C+ C GYY+ + N E
Sbjct: 131 DQRLLDSKCDCDPAGIAG----PCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE---- 182
Query: 457 GSVSYVCDKLTGDCTCKSKYS 477
G C + C ++YS
Sbjct: 183 GCTQCFCYGHSASCRSSAEYS 203
Score = 89.4 bits (212), Expect = 2e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 427 CKYNYAGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
C N G CE C++G+Y C C CN+ GS+S CD +G C+CK +G C+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 483 QCQAGYYNYPTC----------KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
+C G++ C+CD +G CD +G+C+CK G RCD+C S
Sbjct: 115 RCLPGFHMLMDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRS 171
Query: 533 GYYMQVLGRERQCVPCNC 550
GYY G C C C
Sbjct: 172 GYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (212), Expect = 2e-16
Identities = 70/236 (29%), Positives = 90/236 (38%), Gaps = 34/236 (14%)
Query: 1790 GDHCEFCMSGYHGD-ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C SGY D A +G C+ C C +CD + G S + P
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNC-------QGGGACD-PDTGDCYSGDENPDI- 440
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGA 1908
C C G+Y P D CKPC C + + + C C GA
Sbjct: 441 --ECADCPIGFYNDPHDPRS-----CKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGA 491
Query: 1909 ACNLCAPGFYGDAIFS----KNCTACIC----DEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
C LCA G++GD + C C C D +CD TG C+ C G CD
Sbjct: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCD 551
Query: 1960 RCAPDHWG----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
+C ++G N C CNC + SE C D G C C G G C+ A
Sbjct: 552 QCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEHGA 606
Score = 89.0 bits (211), Expect = 3e-16
Identities = 70/231 (30%), Positives = 86/231 (37%), Gaps = 38/231 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-------YPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C C Y G+ C C +GY + TC PCNC G CD +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDEN 437
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK-CN-CLTNFGGAQCDQC 580
C C G+Y R C PC C S S + CN C GA+C+ C
Sbjct: 438 PDIECADCPIGFYNDPHD-PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 581 SPGYYKYP--------DCLSCNCD--VSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQ 628
+ GY+ P C C C+ V S CD G C C N G CD C+
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAG 556
Query: 629 FYNYPA-------CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
++ P C CNC+P G + GC S C CK G C
Sbjct: 557 YFGDPLAPNPADKCRACNCNPMG--SEPVGCRS---DGTCVCKPGFGGPNC 602
Score = 85.0 bits (201), Expect = 5e-15
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 24/148 (16%)
Query: 612 HCKSNFDGAKCDTCREQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C N DG C+ C+ FY + C CNC+ +G + A C + +G C CK V
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--ARCDN--SGR-CSCKPGVT 109
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQ--------CNCNLAGTLNSLGACNTKSGQCVCKQHV 720
G C+ C P + L + GC Q C+C+ AG G C+ +G+CVCK V
Sbjct: 110 GARCDRCLPGFHMLMDA---GCTQDQRLLDSKCDCDPAGIA---GPCD--AGRCVCKPAV 161
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDC 748
+CD+C G+Y L + GCT+C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 85.0 bits (201), Expect = 5e-15
Identities = 52/167 (31%), Positives = 76/167 (45%), Gaps = 21/167 (12%)
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCD 2007
C G C++C + C PCNC S S +CD+ +G+C C GVTG +CD
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 2008 QCAAGFWNYTKDGC--------DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+C GF GC C+C+ G C+A G+C C P V GE+CDRC
Sbjct: 115 RCLPGFHMLMDAGCTQDQRLLDSKCDCDPAGIAG-PCDA-GRCVCKPAVTGERCDRCRSG 172
Query: 2060 WVLIP---QEGCLEC------DSCTDALIFSVEDLSALLANETMDFK 2097
+ + EGC +C SC + +SV +++ + +K
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWK 219
Score = 81.0 bits (191), Expect = 7e-14
Identities = 59/182 (32%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
Query: 1765 CQCNGHSDQC--------DVNTGI-CLNCADNTIGDHCEFCMSGYHGDATVGTPRD-CLI 1814
C CNG S QC G CLNC DNT G HCE C +G++ RD CL
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH----RERDRCLP 83
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPE---DTDLHTG 1871
C C ++ +LS +G C+C+PG GARC+ C G++ + + D
Sbjct: 84 CNC-----NSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLMDAGCTQDQRLL 135
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTAC 1930
D C+ +G P D G C C G C+ C G+Y D + CT C
Sbjct: 136 DSKCDCDPAGIAGPCDAGRC--------VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
Query: 1931 IC 1932
C
Sbjct: 188 FC 189
Score = 77.0 bits (181), Expect = 1e-12
Identities = 48/130 (36%), Positives = 64/130 (49%), Gaps = 19/130 (14%)
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C D G C CK ++ +E + C CNCN G+L++ C+ SG+C CK V
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSA--RCDN-SGRCSCKPGVTG 110
Query: 723 RQCDQCLDGFYRLQTNDVFGCTE--------CDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
+CD+CL GF+ L GCT+ CDCD G I CD G+C C V G
Sbjct: 111 ARCDRCLPGFHMLMDA---GCTQDQRLLDSKCDCDPAG-IAGPCD--AGRCVCKPAVTGE 164
Query: 775 RCDQPIRAHY 784
RCD+ +Y
Sbjct: 165 RCDRCRSGYY 174
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 27/160 (16%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHC 1388
+PC C S + T C C P V G C C GY+G P C+PC C
Sbjct: 460 KPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 1389 -----PS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLG 1436
PS + CD G C+ C N G CD+CK F + C CNCNP+G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 1437 VVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C +D G C C+ G C+H G ++ P CY
Sbjct: 580 --SEPVGCRSD-GTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 72.1 bits (169), Expect = 3e-11
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 27/198 (13%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYG-------FPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
QC C G+ C C +GY F C PC+C CD D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 1410 NCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCV 1466
C C P F D R C C C+ + E + C C V G C+ C
Sbjct: 441 ECADC-PIGFYNDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1467 PGHYAFP--------DCYQCTCNRH--GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEY 1515
G++ P C C CN + + CD+ T +C C N G CD CK Y
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1516 FN--LQDDNPDGCTKCFC 1531
F L + D C C C
Sbjct: 558 FGDPLAPNPADKCRACNC 575
Score = 71.7 bits (168), Expect = 5e-11
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF 286
C CNG + C E GN C NT G C KC +GF + + R DR
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN-GFRCLNCNDNTDGIHCEKCKNGFYRHRER-----DR- 80
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY- 345
C PCNC++ + ++ R + G+C +C+ G C++C P ++
Sbjct: 81 -CLPCNCNSKGS----------------LSARCDNSGRC-SCKPGVTGARCDRCLPGFHM 122
Query: 346 -RPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCK 404
G D+ + C CDP G C ++GRC C+P C C GY++
Sbjct: 123 LMDAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 405 PCTC 408
P C
Sbjct: 181 PEGC 184
Score = 68.1 bits (159), Expect = 6e-10
Identities = 45/154 (29%), Positives = 65/154 (42%), Gaps = 22/154 (14%)
Query: 252 LVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
+VC C G +C C G+ + ++ C+PC C+N+ DP
Sbjct: 479 VVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQCNNNV-----DPSASGNC 531
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYGKRWDELDVCQPCQCDPHFST 369
L G+CL C HNT GI C++C+ Y+ P + D C+ C C+P S
Sbjct: 532 DRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAP--NPADKCRACNCNPMGSE 581
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
G C C+P F P+C +G F P C
Sbjct: 582 PVGCRSDGTCVCKPGFGGPNCE---HGAFSCPAC 612
Score = 67.3 bits (157), Expect = 1e-09
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1947 CVCRPGVIGEKCDRCAPDHWGLNTGLG----CTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
C+C G G+ C CA + + LG C PCNC CD D G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC---QGGGACDPDTGDCYSGDENP 438
Query: 2003 GKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
+C C GF+N D C C C+ G+S M C C PGV G +C+ C +
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
Score = 55.2 bits (127), Expect = 4e-06
Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 26/189 (13%)
Query: 611 CHCKSNFDGAKCDTCREQFYN-------YPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
C C + G C C + + C CNC G G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD--------CYS 433
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGE 722
D C DC ++N ++P C+ C C+ + + + T+ C C V
Sbjct: 434 GDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMP--ETEEVVCNNCPPGVTG 490
Query: 723 RQCDQCLDGFYRLQTND---VFGCTECDCD--IGGSIDNNCDKTTGQC-HCHSRVEGRRC 776
+C+ C DG++ + V C C C+ + S NCD+ TG+C C G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 777 DQPIRAHYF 785
DQ +A YF
Sbjct: 551 DQ-CKAGYF 558
Score = 54.4 bits (125), Expect = 7e-06
Identities = 39/125 (31%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLY-WNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQ 713
P E C C +G+ C DC Y + PFG C CNC G GAC+ +G
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ-GG-----GACDPDTGD 430
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVE 772
C + +C C GFY +D C C C G S + C +C V
Sbjct: 431 CYSGDENPDIECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 773 GRRCD 777
G RC+
Sbjct: 490 GARCE 494
Score = 37.1 bits (82), Expect = 1.2
Identities = 19/82 (23%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 240 CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTE 299
C+PA AG + C C+ G +C++C SG+ + C C C+ H+
Sbjct: 141 CDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSAS 195
Query: 300 CTYDPEIDEKRLSLDINGRYEG 321
C E +++ + +G
Sbjct: 196 CRSSAEYSVHKITSTFHQDVDG 217
>AF028816-1|AAC95123.1| 1761|Homo sapiens laminin beta-4 chain
precursor protein.
Length = 1761
Score = 290 bits (712), Expect = 6e-77
Identities = 142/366 (38%), Positives = 190/366 (51%), Gaps = 24/366 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C G C++C G++ PS C PC CN ++ CD TG C NC T G +CE
Sbjct: 835 QCPCHGEVSGRRCDRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCE 892
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNN-FALSCDLSENGSLISCNCQPGYGGARCE 1853
C+ GY+G+ + G P C C CP SN FA SC + S + CNC GY G +C
Sbjct: 893 RCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCG 950
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
C+ G+YG P + G C+PC C+ NI+ DP SC + G+CL+C++NT GA C LC
Sbjct: 951 ECSTGFYGNPRIS----GAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLC 1006
Query: 1914 APGFYGDAIFSKNCTACICDEFGMAD-----------CDSTTGTCVCRPGVIGEKCDRCA 1962
PG YG A+ ++ C C C G++ CD TG C C P V G CDRCA
Sbjct: 1007 KPGHYGSAL-NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
Query: 1963 PDHWGLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
+W L G GC C+C S+S+ CD GQC C G GK+C +C ++ C
Sbjct: 1066 DGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRC 1125
Query: 2022 DHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIF 2080
C+CN + +C+ TG C C GV G++CDRC R CL+C C D
Sbjct: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC-ARGHSQEFPTCLQCHLCFDQWDH 1184
Query: 2081 SVEDLS 2086
++ LS
Sbjct: 1185 TISSLS 1190
Score = 249 bits (609), Expect = 2e-64
Identities = 142/418 (33%), Positives = 194/418 (46%), Gaps = 45/418 (10%)
Query: 406 CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS---PECKNCECNTVGSVSYV 462
C C+ G+ G C+ G C CK G+ C+ C G Y C C C+ GS V
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTV 828
Query: 463 CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
CD++TG C C + SGR C++C AGY+ +P+C PC C+ +CD +G C GF
Sbjct: 829 CDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFA---ELCDPETGSCFNCGGF 885
Query: 523 -GGPRCDQCLSGYYMQVLGRERQCVPCNC--DPTGST--STSC-----SADGKCNCLTNF 572
G C++C+ GYY + C PC C DP+ + + SC S+D CNCL +
Sbjct: 886 TTGRNCERCIDGYYGNP-SSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGY 944
Query: 573 GGAQCDQCSPGYYKYP-----DCLSCNC--DVSGSIGSTCDD-NGLC-HCKSNFDGAKCD 623
G QC +CS G+Y P C C C ++ + +C G C C N GA C
Sbjct: 945 TGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ 1004
Query: 624 TCREQFYN---YPACEECNCDPRGVT-----ASFAGCGSVPAGELCQCKDRVQGRICNDC 675
C+ Y C C+C GV+ C P C C V G C+ C
Sbjct: 1005 LCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRC 1064
Query: 676 KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRL 735
YWNL GC+ C+C+ + +S C+ +GQC CK G ++C +C + +Y
Sbjct: 1065 ADGYWNLVPGR--GCQSCDCDPRTSQSS--HCDQLTGQCPCKLGYGGKRCSECQENYY-- 1118
Query: 736 QTNDVFG-CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH--YFPTLHQ 790
D G C CDC+ G+ CD TG C C V G+RCD+ R H FPT Q
Sbjct: 1119 --GDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQ 1174
Score = 235 bits (575), Expect = 2e-60
Identities = 147/502 (29%), Positives = 236/502 (47%), Gaps = 59/502 (11%)
Query: 29 KKTSVCDI---CDANNEAKKHPPE-----YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLG 80
+K S+CD D ++ H E + D + WWQS G+ + V++ +DL
Sbjct: 67 QKCSICDSRFPYDPYDQPNSHTIENVTVSFEPDREKKWWQS---ENGLDH--VSIRLDLE 121
Query: 81 QEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITK 140
F +++ + + RP ++E+STDYG +K ++YF+ +DC F +
Sbjct: 122 ALFRFSHLILTF-KTFRPAAMLVERSTDYGHNWKVFKYFA---KDCATSFPNITSGQAQG 177
Query: 141 DDSVICSTEYSKIVPLEDGEIPISLLNDR-PSSNMYFNSSVLQEWTRATNVRLRLLRTKN 199
++C ++YS I P GE+ + +L+ N Y S +Q+ TN+R+ + +
Sbjct: 178 VGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPY--SPYIQDLVTLTNLRINFTKL-H 234
Query: 200 LLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPAD--------PAGNLNI 251
LG + RQ+ ++ + Y+Y++ ++ + G C CNGHA C P P G ++
Sbjct: 235 TLGDALLGRRQNDSLDK-YYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHG 293
Query: 252 LVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRL 311
C CQHNT GP C +C F+ WR + + +C C+C++H++ C +D +
Sbjct: 294 Q-CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFD-------M 345
Query: 312 SLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPH--FST 369
+ + GG C +CQHNTEG +C++CRP +YR K + C PC+CDP S
Sbjct: 346 TTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISG 405
Query: 370 GNCEEES--------GRCECRPEFQPPDCSSCAYGYF-----DYPNCKPCTCN-LNGTEG 415
G C S G+C C+ + C C ++ D C+PC CN L
Sbjct: 406 GICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPF 465
Query: 416 EHCTPTDGLCPCKYNYAGKSCEICEDGYYS-----PECKNCECNTVGSVSYVCDKLTGDC 470
C G C C G CE C GY+ C C+C+ G+ S VC G C
Sbjct: 466 LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQC 525
Query: 471 TCKSKYSGRTCNQCQAGYYNYP 492
C+ +GR+C++ GY+ P
Sbjct: 526 ECRPHVTGRSCSEPAPGYFFAP 547
Score = 219 bits (534), Expect = 2e-55
Identities = 141/473 (29%), Positives = 206/473 (43%), Gaps = 50/473 (10%)
Query: 361 CQCDPHFSTGN-CEEESGRCECRPEFQPPDCSSCAYGYFD--YPNCKPCTCNLNGTEGEH 417
C+C P S G+ C G+C+C+P C C+ G +D + C PC C+ G++
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTV 828
Query: 418 CTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
C G CPC +G+ C+ C GY+ P C C CN +CD TG C C
Sbjct: 829 CDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAE---LCDPETGSCFNCGGF 885
Query: 476 YSGRTCNQCQAGYYNYPT----CKPCNC--DTSGTE---PSICDDVSGQ---CICKAGFG 523
+GR C +C GYY P+ C+PC C D S + S ++ C C G+
Sbjct: 886 TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYT 945
Query: 524 GPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTS--TSCS-ADGKC-NCLTNFGGAQCDQ 579
G +C +C +G+Y C PC C+ + SCS G+C CL N GA C
Sbjct: 946 GTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL 1005
Query: 580 CSPGYY---KYPDCLSCNCDVSGSIGSTCDD----------NGLCHCKSNFDGAKCDTCR 626
C PG+Y C C+C SG C G C C N G CD C
Sbjct: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
Query: 627 EQFYNY---PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ ++N C+ C+CDPR T+ + C + G+ C CK G+ C++C+ Y+
Sbjct: 1066 DGYWNLVPGRGCQSCDCDPR--TSQSSHCDQL-TGQ-CPCKLGYGGKRCSECQENYYG-- 1119
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGC 743
P C C+CN AGT + C+ +G C C++ V ++CD+C G + + C
Sbjct: 1120 -DPPGRCIPCDCNRAGTQKPI--CDPDTGMCRCREGVSGQRCDRCARG-HSQEFPTCLQC 1175
Query: 744 TECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQFQYEVE 796
C +I + G + +E +R P+ F L E+E
Sbjct: 1176 HLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRGNVSEIE 1228
Score = 203 bits (496), Expect = 8e-51
Identities = 125/391 (31%), Positives = 171/391 (43%), Gaps = 51/391 (13%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGRCE 380
GG+C C+ G C++C Y G C PC C P S C++ +G+C
Sbjct: 785 GGQC-QCKPLVVGRCCDRCSTGSY-DLGHHG-----CHPCHCHPQGSKDTVCDQVTGQCP 837
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEIC 439
C E C C GYF +P+C PC CN E C P G C C G++CE C
Sbjct: 838 CHGEVSGRRCDRCLAGYFGFPSCHPCPCN---RFAELCDPETGSCFNCGGFTTGRNCERC 894
Query: 440 EDGYY-SPE----CKNCEC------NTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQA 486
DGYY +P C+ C C N + S + + D C C Y+G C +C
Sbjct: 895 IDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECST 954
Query: 487 GYYNYP-----TCKPCNCDTS--GTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYMQV 538
G+Y P C+PC C+ + T+P C V+G+C+ C G C C G+Y
Sbjct: 955 GFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA 1014
Query: 539 LGRE-RQC-------VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY--- 587
L + R+C P C P G G C CL N G CD+C+ GY+
Sbjct: 1015 LNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPG 1074
Query: 588 PDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRG 644
C SC+CD S S CD G C CK + G +C C+E +Y P C C+C+ G
Sbjct: 1075 RGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAG 1134
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDC 675
P +C+C++ V G+ C+ C
Sbjct: 1135 TQKPICD----PDTGMCRCREGVSGQRCDRC 1161
Score = 189 bits (461), Expect = 1e-46
Identities = 117/404 (28%), Positives = 175/404 (43%), Gaps = 78/404 (19%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH----------TTECTYD 303
C+C+ G C++C +G S + C PC+CH T +C
Sbjct: 788 CQCKPLVVGRCCDRCSTG--------SYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCH 839
Query: 304 PEIDEKRLSLDINGRY------------------EGGGKCLNCQHNTEGINCNKCRPTYY 345
E+ +R + G + G C NC T G NC +C Y
Sbjct: 840 GEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGY- 898
Query: 346 RPYGKRWDELDVCQPCQC--DP-------HFSTGNCEEESGRCECRPEFQPPDCSSCAYG 396
YG C+PC C DP H N C C + C C+ G
Sbjct: 899 --YGNP-SSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTG 955
Query: 397 YFDYPN-----CKPCTC--NLNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYY---- 444
++ P C+PC C N++ T+ E C+ G C C +N G +C++C+ G+Y
Sbjct: 956 FYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSAL 1015
Query: 445 SPECKNCECNT---------VGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT-- 493
+ C+ C C+ G + +CD +TG C C +G C++C GY+N
Sbjct: 1016 NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR 1075
Query: 494 -CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDP 552
C+ C+CD ++ S CD ++GQC CK G+GG RC +C YY GR C+PC+C+
Sbjct: 1076 GCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGR---CIPCDCNR 1132
Query: 553 TGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGY-YKYPDCLSCN 594
G+ C D G C C G +CD+C+ G+ ++P CL C+
Sbjct: 1133 AGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCH 1176
Score = 183 bits (446), Expect = 9e-45
Identities = 122/369 (33%), Positives = 150/369 (40%), Gaps = 57/369 (15%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCN--GHSDQ-CDVNTGICLNCADNTIGD 1791
+CQC G C++C+ G Y L C PC C+ G D CD TG C C G
Sbjct: 787 QCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQC-PCHGEVSGR 845
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C+ C++GY G + C C C N FA CD E GS NC G
Sbjct: 846 RCDRCLAGYFGFPS------CHPCPC------NRFAELCD-PETGSCF--NCGGFTTGRN 890
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK----------C 1901
CE C GYYG P +G C+PC C P DP S C + C
Sbjct: 891 CERCIDGYYGNPS-----SGQPCRPCLC-----PDDPSSNQYFAHSCYQNLWSSDVICNC 940
Query: 1902 VNNTAGAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIG 1955
+ G C C+ GFYG+ I C C C D C TG C+ C G
Sbjct: 941 LQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQG 1000
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ----------CDDDNGQCRCAKGVTGKQ 2005
C C P H+G C C+C + S CD G C C VTG
Sbjct: 1001 ANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLA 1060
Query: 2006 CDQCAAGFWNYTKD-GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLI 2063
CD+CA G+WN GC C+C+ S C+ TGQC C G G++C C E +
Sbjct: 1061 CDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGD 1120
Query: 2064 PQEGCLECD 2072
P C+ CD
Sbjct: 1121 PPGRCIPCD 1129
Score = 176 bits (428), Expect = 1e-42
Identities = 97/275 (35%), Positives = 136/275 (49%), Gaps = 39/275 (14%)
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC---------DVSGSIGST 604
G+C C N G C++C + P C SC+C D++ + S
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
Query: 605 CDDNGLCH-CKSNFDGAKCDTCREQFYNYP--------ACEECNCDPRG-------VTAS 648
G+C C+ N +G CD CR FY P AC C CDP G V+ S
Sbjct: 353 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS 412
Query: 649 FAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN 708
GSV AG+ C CK+ V+G C+ CKP ++ L +P GC+ C+CN G+L L C+
Sbjct: 413 DPALGSV-AGQ-CLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL-TCD 469
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH 768
+GQC+C +V C++C G++ L N + GC+ CDCDIGG+ N C GQC C
Sbjct: 470 VDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDCDIGGAYSNVCSPKNGQCECR 528
Query: 769 SRVEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSG 803
V GR C +P ++F L+ + YE E+ T G
Sbjct: 529 PHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQG 563
Score = 163 bits (396), Expect = 1e-38
Identities = 97/326 (29%), Positives = 139/326 (42%), Gaps = 45/326 (13%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN A+ C+P + N C T G C +C G+ C P
Sbjct: 863 CPCNRFAELCDP-ETGSCFN-----CGGFTTGRNCERCIDGY------YGNPSSGQPCRP 910
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C + DP ++ + C NC G C +C + YG
Sbjct: 911 CLCPD-------DPSSNQYFAHSCYQNLWSSDVIC-NCLQGYTGTQCGECSTGF---YGN 959
Query: 351 RWDELDVCQPCQCDPHFST---GNCEEESGRC-ECRPEFQPPDCSSCAYGYFD---YPNC 403
CQPC C+ + +C +G C C Q +C C G++ C
Sbjct: 960 PRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTC 1019
Query: 404 KPCTCNLNGTEGEH---------CTPTDGLCPCKYNYAGKSCEICEDGYYS----PECKN 450
+ C+C+ +G C P G CPC N G +C+ C DGY++ C++
Sbjct: 1020 RRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQS 1079
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP--TCKPCNCDTSGTEPSI 508
C+C+ S S CD+LTG C CK Y G+ C++CQ YY P C PC+C+ +GT+ I
Sbjct: 1080 CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPI 1139
Query: 509 CDDVSGQCICKAGFGGPRCDQCLSGY 534
CD +G C C+ G G RCD+C G+
Sbjct: 1140 CDPDTGMCRCREGVSGQRCDRCARGH 1165
Score = 157 bits (382), Expect = 5e-37
Identities = 84/259 (32%), Positives = 119/259 (45%), Gaps = 30/259 (11%)
Query: 252 LVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRL 311
++C C G QC +C +GF RIS C+PC C+N+ DPE R+
Sbjct: 936 VICNCLQGYTGTQCGECSTGFYGNP-RISGA----PCQPCACNNNID--VTDPE-SCSRV 987
Query: 312 SLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQ-----PCQCDPH 366
+ G+CL C HNT+G NC C+P +Y + C P +C P
Sbjct: 988 T----------GECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPG 1037
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP---NCKPCTCNLNGTEGEHCTPTDG 423
C+ +G C C P C CA GY++ C+ C C+ ++ HC G
Sbjct: 1038 GGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTG 1097
Query: 424 LCPCKYNYAGKSCEICEDGYYSP---ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRT 480
CPCK Y GK C C++ YY C C+CN G+ +CD TG C C+ SG+
Sbjct: 1098 QCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQR 1157
Query: 481 CNQCQAGY-YNYPTCKPCN 498
C++C G+ +PTC C+
Sbjct: 1158 CDRCARGHSQEFPTCLQCH 1176
Score = 136 bits (328), Expect = 2e-30
Identities = 81/243 (33%), Positives = 108/243 (44%), Gaps = 31/243 (12%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP--EDTDLHTGDYCKPCNCSGNIN------PQDPGSCD 1892
C CQ G CE C + P DL + C+ C+C+ + + S
Sbjct: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQD-NACRSCSCNSHSSRCHFDMTTYLASGG 353
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN----CTACICDEFGMAD---C----- 1940
G C C +NT G C+ C P FY D + + + C C CD G C
Sbjct: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413
Query: 1941 ---DSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNCGIASEST--QCDDDNG 1993
S G C+C+ V G KCD+C P+H+GL+ LGC PC+C CD D G
Sbjct: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTG 473
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIG 2050
QC C VTG C++C G+W GC C+C+ G + +C+ GQCEC P V G
Sbjct: 474 QCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTG 533
Query: 2051 EKC 2053
C
Sbjct: 534 RSC 536
Score = 132 bits (318), Expect = 3e-29
Identities = 94/285 (32%), Positives = 124/285 (43%), Gaps = 40/285 (14%)
Query: 1765 CQCNGHSDQC--------DVNT------GICLNCADNTIGDHCEFCMSGYHGDATVGTPR 1810
C CNGH+ +C DV + G C+ C NT G +CE C + DA
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQ-DAPWRPAA 322
Query: 1811 D-----CLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIP 1863
D C C+C +F ++ L+ G + +CQ G C+ C +Y P
Sbjct: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDP 382
Query: 1864 EDTDLHTGDYCKPCNC------SGNI--NPQDPGSCDSINGDCLKCVNNTAGAACNLCAP 1915
T + C PC C SG I + DP + S+ G CL C N GA C+ C P
Sbjct: 383 LKT-ISDPYACIPCECDPDGTISGGICVSHSDP-ALGSVAGQCL-CKENVEGAKCDQCKP 439
Query: 1916 GFYG-DAIFSKNCTACICDEFG---MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
YG A C C C+ G CD TG C+C V G C+ C +WGL
Sbjct: 440 NHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNH 499
Query: 1972 L-GCTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
L GC+PC+C I S C NGQC C VTG+ C + A G++
Sbjct: 500 LHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 128 bits (310), Expect = 3e-28
Identities = 97/368 (26%), Positives = 144/368 (39%), Gaps = 45/368 (12%)
Query: 1197 PGEYLFMVHYYQPDHPESTMEVTVNTDGQKQETNLP--IQHCPSNSGCRALLR------- 1247
P ++ +HY + T+++ VN G + +P +Q P + A R
Sbjct: 617 PVDFTIAIHYETQSAADWTVQIVVNPPGGSEHC-IPKTLQSKPQSFALPAATRIMLLPTP 675
Query: 1248 ---KPDTSTSFLVNENFTLVFKGNTSKGVWLDYVLVIEASDFTDAVLTEANILDYTREFI 1304
+PD S V + L + + V +D + +I + + ++ ++ +Y +
Sbjct: 676 ICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLENFCSKQDLDEYQ---L 732
Query: 1305 EQCASYNYYISPNET-GLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKP 1363
C + P G C + S++++ + GA C C GS C+ GGQC CKP
Sbjct: 733 HNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKP 792
Query: 1364 NVIGRTCSACRTGYY--GFPNCRPCHC----PSTAICDD-NGMCICPKNVEGENCDRCKP 1416
V+GR C C TG Y G C PCHC +CD G C C V G CDRC
Sbjct: 793 LVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLA 852
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-ACRENVRGRVCDHCVPGHYAFPD- 1474
F F C C CN + C+ ++G C C GR C+ C+ G+Y P
Sbjct: 853 GYFGFP---SCHPCPCNRFAEL-----CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSS 904
Query: 1475 ---CYQCTC--NRHGTTY--DVCDQN----TAQCYCKTNVRGQACDTCKEEYFNLQDDNP 1523
C C C + Y C QN C C G C C ++ +
Sbjct: 905 GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISG 964
Query: 1524 DGCTKCFC 1531
C C C
Sbjct: 965 APCQPCAC 972
Score = 126 bits (305), Expect = 1e-27
Identities = 95/312 (30%), Positives = 135/312 (43%), Gaps = 43/312 (13%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P + G G +C+ CQHNT+G NC +C+ + P+
Sbjct: 265 CFCNGHASECR--PMQKMRGDVFSPPGMVHG--QCV-CQHNTDGPNCERCKDFFQDAPWR 319
Query: 350 KRWDELD-VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
D D C+ C +C S RC F + A G C+ C
Sbjct: 320 PAADLQDNACRSC---------SCNSHSSRCH----FDMT--TYLASGGLSGGVCEDCQH 364
Query: 409 NLNGTEGEHCTPT---DGLCPCKYNYAGKSCEICEDGYYSPE-CKNCECNTVGSVSYVCD 464
N G + C P D L YA CE DG S C + +GSV+
Sbjct: 365 NTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVA---- 420
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPT-----CKPCNCDTSGTEPSI-CDDVSGQCIC 518
G C CK G C+QC+ +Y C+PC+C+ G+ P + CD +GQC+C
Sbjct: 421 ---GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLC 477
Query: 519 KAGFGGPRCDQCLSGYYMQVLGRERQ-CVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQ 576
+ G C++C GY+ LG C PC+CD G+ S CS +G+C C + G
Sbjct: 478 LSYVTGAHCEECTVGYWG--LGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRS 535
Query: 577 CDQCSPGYYKYP 588
C + +PGY+ P
Sbjct: 536 CSEPAPGYFFAP 547
Score = 123 bits (297), Expect = 1e-26
Identities = 75/247 (30%), Positives = 105/247 (42%), Gaps = 29/247 (11%)
Query: 1318 ETGLCREAMFSITSEYNSGARPCLCDF-MGSTELE-CNTFGGQC-PCKPNVIGRTCSACR 1374
+ G C + + +PC C+ + T+ E C+ G+C C N G C C+
Sbjct: 948 QCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCK 1007
Query: 1375 TGYYGFP---NCRPCHCPSTAI-------------CDD-NGMCICPKNVEGENCDRCKPY 1417
G+YG CR C C ++ + CD G C C NV G CDRC
Sbjct: 1008 PGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADG 1067
Query: 1418 TFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--C 1475
+N RGC C+C+P C+ +G+C C+ G+ C C +Y P C
Sbjct: 1068 YWNLVPGRGCQSCDCDPR--TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRC 1125
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKC-FCFGK 1534
C CNR GT +CD +T C C+ V GQ CD C + + P C +C CF +
Sbjct: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGH---SQEFPT-CLQCHLCFDQ 1181
Query: 1535 TTRCSSS 1541
SS
Sbjct: 1182 WDHTISS 1188
Score = 120 bits (290), Expect = 7e-26
Identities = 77/257 (29%), Positives = 109/257 (42%), Gaps = 31/257 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC--DVNT------ 1778
+C C G +CE+C + P C C CN HS +C D+ T
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 353
Query: 1779 ---GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICAC-PMPYPSNNFALSCDL 1832
G+C +C NT G HC+ C ++ D T+ P C+ C C P S +S
Sbjct: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413
Query: 1833 SENGSLI-SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC 1891
GS+ C C+ GA+C+ C +YG+ L C+PC+C+ + +C
Sbjct: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG----CQPCDCN-PLGSLPFLTC 468
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVC 1949
D G CL C++ GA C C G++G C+ C CD G C G C C
Sbjct: 469 DVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCEC 527
Query: 1950 RPGVIGEKCDRCAPDHW 1966
RP V G C AP ++
Sbjct: 528 RPHVTGRSCSEPAPGYF 544
Score = 117 bits (281), Expect = 9e-25
Identities = 80/259 (30%), Positives = 101/259 (38%), Gaps = 22/259 (8%)
Query: 546 VPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYK--YPDCLSCNCDVSGSIG 602
V C C P GS +SCS G+C C G CD+CS G Y + C C+C GS
Sbjct: 767 VACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKD 826
Query: 603 STCDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELC 661
+ CD G C C G +CD C ++ +P+C C C+ FA G
Sbjct: 827 TVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCN------RFAELCDPETGSCF 880
Query: 662 QCKDRVQGRICNDC-KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGA--C--NTKSGQ--C 714
C GR C C Y N P C C C + N A C N S C
Sbjct: 881 NCGGFTTGRNCERCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC 938
Query: 715 VCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC--DIGGSIDNNCDKTTGQC-HCHSRV 771
C Q QC +C GFY C C C +I + +C + TG+C C
Sbjct: 939 NCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNT 998
Query: 772 EGRRCDQPIRAHYFPTLHQ 790
+G C HY L+Q
Sbjct: 999 QGANCQLCKPGHYGSALNQ 1017
Score = 115 bits (276), Expect = 4e-24
Identities = 71/215 (33%), Positives = 90/215 (41%), Gaps = 22/215 (10%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA-IC 1394
G PC C GS + C+ GQCPC V GR C C GY+GFP+C PC C A +C
Sbjct: 813 GCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELC 872
Query: 1395 D-DNGMCI-CPKNVEGENCDRC-KPYTFNFDVQRGCDDCNCNPLGVVGNQL---QCEADS 1448
D + G C C G NC+RC Y N + C C C P NQ C +
Sbjct: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLC-PDDPSSNQYFAHSCYQNL 931
Query: 1449 GK----CACRENVRGRVCDHCVPGHYAFP-----DCYQCTCNRH--GTTYDVCDQNTAQC 1497
C C + G C C G Y P C C CN + T + C + T +C
Sbjct: 932 WSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGEC 991
Query: 1498 Y-CKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C N +G C CK ++ + C +C C
Sbjct: 992 LRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSC 1024
Score = 114 bits (274), Expect = 7e-24
Identities = 64/198 (32%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASF-----AGC 652
+G C C+ N DG C+ C++ F + P AC C+C+ F
Sbjct: 292 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWN--LQEY-NPFGCEQCNCNLAGTLNSLGACNT 709
G + G C+ +G+ C+ C+PL++ L+ +P+ C C C+ GT++ G C +
Sbjct: 352 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISG-GICVS 410
Query: 710 KS--------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSID-NNCDK 760
S GQC+CK++V +CDQC Y L D GC CDC+ GS+ CD
Sbjct: 411 HSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDV 470
Query: 761 TTGQCHCHSRVEGRRCDQ 778
TGQC C S V G C++
Sbjct: 471 DTGQCLCLSYVTGAHCEE 488
Score = 111 bits (267), Expect = 5e-23
Identities = 68/205 (33%), Positives = 92/205 (44%), Gaps = 31/205 (15%)
Query: 1342 CDFMGSTELECNTF-GGQCP-CKPNVIGRTCSACRTGYYGFP--------NCRPCHCP-- 1389
C F +T L GG C C+ N G+ C CR +Y P C PC C
Sbjct: 341 CHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPD 400
Query: 1390 ---STAICDDN---------GMCICPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPL 1435
S IC + G C+C +NVEG CD+CKP Y + GC C+CNPL
Sbjct: 401 GTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPL 460
Query: 1436 GVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD----CYQCTCNRHGTTYDVCD 1491
G + L C+ D+G+C C V G C+ C G++ + C C C+ G +VC
Sbjct: 461 GSLPF-LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCS 519
Query: 1492 QNTAQCYCKTNVRGQACDTCKEEYF 1516
QC C+ +V G++C YF
Sbjct: 520 PKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 106 bits (255), Expect = 1e-21
Identities = 78/282 (27%), Positives = 117/282 (41%), Gaps = 54/282 (19%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
G C C++N G +CE C+D + + + + D C+C S S
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWR--------PAADLQDNACRSCSCNSHSS----- 339
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVL 539
+C Y + G +C+D C+ G CD+C +Y ++ +
Sbjct: 340 RCHFDMTTYLA-------SGGLSGGVCED------CQHNTEGQHCDRCRPLFYRDPLKTI 386
Query: 540 GRERQCVPCNCDPTGSTSTS-C---------SADGKCNCLTNFGGAQCDQCSPGYYKYP- 588
C+PC CDP G+ S C S G+C C N GA+CDQC P +Y
Sbjct: 387 SDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSA 446
Query: 589 ----DCLSCNCDVSGSIG-STCD-DNGLCHCKSNFDGAKCDTCREQFY----NYPACEEC 638
C C+C+ GS+ TCD D G C C S GA C+ C ++ + C C
Sbjct: 447 TDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPC 506
Query: 639 NCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYW 680
+CD G ++ P C+C+ V GR C++ P Y+
Sbjct: 507 DCDIGGAYSNVCS----PKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 103 bits (246), Expect = 2e-20
Identities = 67/218 (30%), Positives = 94/218 (43%), Gaps = 45/218 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPS-TAICD---------- 1395
GQC C+ N G C C+ + P CR C C S ++ C
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNFDVQR-----GCDDCNCNPLGVVGNQLQCEAD 1447
G+C C N EG++CDRC+P + ++ C C C+P G + + C +
Sbjct: 353 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGI-CVSH 411
Query: 1448 S--------GKCACRENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTT-YDVCDQN 1493
S G+C C+ENV G CD C P HY C C CN G+ + CD +
Sbjct: 412 SDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVD 471
Query: 1494 TAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
T QC C + V G C+ C Y+ L ++ GC+ C C
Sbjct: 472 TGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGCSPCDC 508
Score = 94.3 bits (224), Expect = 7e-18
Identities = 55/155 (35%), Positives = 74/155 (47%), Gaps = 14/155 (9%)
Query: 1929 ACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASES 1985
AC C G + C G C C+P V+G CDRC+ + L GC PC+C S+
Sbjct: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHH-GCHPCHCHPQGSKD 826
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQC-E 2043
T CD GQC C V+G++CD+C AG++ + C C CN +C+ TG C
Sbjct: 827 TVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF--PSCHPCPCN---RFAELCDPETGSCFN 881
Query: 2044 CLPGVIGEKCDRCPERWVLIPQEG--CLECDSCTD 2076
C G C+RC + + P G C C C D
Sbjct: 882 CGGFTTGRNCERCIDGYYGNPSSGQPCRPC-LCPD 915
Score = 85.8 bits (203), Expect = 3e-15
Identities = 45/129 (34%), Positives = 61/129 (47%), Gaps = 14/129 (10%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI----CD-DNGMCICPKN 1405
GQC CK NV G C C+ +YG C+PC C P ++ CD D G C+C
Sbjct: 421 GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY 480
Query: 1406 VEGENCDRCKPYTFNFDVQ-RGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH 1464
V G +C+ C + GC C+C+ G N C +G+C CR +V GR C
Sbjct: 481 VTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNV--CSPKNGQCECRPHVTGRSCSE 538
Query: 1465 CVPGHYAFP 1473
PG++ P
Sbjct: 539 PAPGYFFAP 547
Score = 80.2 bits (189), Expect = 1e-13
Identities = 51/166 (30%), Positives = 69/166 (41%), Gaps = 31/166 (18%)
Query: 1397 NGMCICPKNVEGENCDRCK------PYTFNFDVQ-RGCDDCNCNP------LGVVGNQLQ 1443
+G C+C N +G NC+RCK P+ D+Q C C+CN +
Sbjct: 292 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
Query: 1444 CEADSGKCA-CRENVRGRVCDHCVPGHYAFP--------DCYQCTCNRHGT-TYDVCDQN 1493
G C C+ N G+ CD C P Y P C C C+ GT + +C +
Sbjct: 352 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSH 411
Query: 1494 T--------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ QC CK NV G CD CK ++ L +P GC C C
Sbjct: 412 SDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDC 457
Score = 77.4 bits (182), Expect = 9e-13
Identities = 64/219 (29%), Positives = 88/219 (40%), Gaps = 42/219 (19%)
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDA-------IFSKNCTACICDEFGM-ADCDSTT- 1944
++G C+ C +NT G C C F+ DA + C +C C+ D TT
Sbjct: 291 VHGQCV-CQHNTDGPNCERCKD-FFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTY 348
Query: 1945 --------GTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG---------- 1980
G C C+ G+ CDRC P + ++ C PC C
Sbjct: 349 LASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGIC 408
Query: 1981 IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFM-C 2036
++ GQC C + V G +CDQC + + GC C+CN S+ F+ C
Sbjct: 409 VSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTC 468
Query: 2037 NA-TGQCECLPGVIGEKCDRCP-ERWVLIPQ-EGCLECD 2072
+ TGQC CL V G C+ C W L GC CD
Sbjct: 469 DVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCD 507
Score = 70.5 bits (165), Expect = 1e-10
Identities = 49/138 (35%), Positives = 58/138 (42%), Gaps = 21/138 (15%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCNGHSD----QCDVNTGICLNCAD 1786
+C C G C+QC HY L P G C PC CN CDV+TG CL C
Sbjct: 422 QCLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTGQCL-CLS 479
Query: 1787 NTIGDHCEFCMSGYHGDATVGTP-RDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
G HCE C GY G +G C C C + +N C +NG C C+P
Sbjct: 480 YVTGAHCEECTVGYWG---LGNHLHGCSPCDCDIGGAYSNV---CS-PKNG---QCECRP 529
Query: 1846 GYGGARCEYCAAGYYGIP 1863
G C A GY+ P
Sbjct: 530 HVTGRSCSEPAPGYFFAP 547
Score = 70.5 bits (165), Expect = 1e-10
Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 1927 CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGI-ASES 1985
C+ DE+ + +C P V+ C+R G C C S
Sbjct: 722 CSKQDLDEYQLHNCVEIASAM--GPQVLPGACERLIIS-MSAKLHDGAVACKCHPQGSVG 778
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCEC 2044
+ C GQC+C V G+ CD+C+ G ++ GC C+C+ S +C+ TGQC C
Sbjct: 779 SSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPC 838
Query: 2045 LPGVIGEKCDRC 2056
V G +CDRC
Sbjct: 839 HGEVSGRRCDRC 850
Score = 63.7 bits (148), Expect = 1e-08
Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
C+ + +++ G +PC C+ +GS L C+ GQC C V G C C GY+G
Sbjct: 437 CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL 496
Query: 1381 PN----CRPCHCP-----STAICDDNGMCICPKNVEGENCDRCKPYTF 1419
N C PC C S NG C C +V G +C P F
Sbjct: 497 GNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 49.6 bits (113), Expect = 2e-04
Identities = 20/46 (43%), Positives = 26/46 (56%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
G PC CD G+ C+ GQC C+P+V GR+CS GY+ P
Sbjct: 502 GCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 39.9 bits (89), Expect = 0.17
Identities = 15/37 (40%), Positives = 20/37 (54%)
Query: 742 GCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G C C GS+ ++C + GQC C V GR CD+
Sbjct: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR 801
>X79683-1|CAA56130.1| 1798|Homo sapiens beta2/S laminin chain protein.
Length = 1798
Score = 288 bits (706), Expect = 3e-76
Identities = 141/366 (38%), Positives = 185/366 (50%), Gaps = 21/366 (5%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C GL C+ C G + PS C PC CNGH+D+C+ +TG CL C D T G+HCE
Sbjct: 849 QCLCRTGAFGLRCDACQRGQWGFPS--CRPCVCNGHADECNTHTGACLGCRDLTGGEHCE 906
Query: 1795 FCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C++G+HGD + C C CP P +FA SC E I C+C+ GY G RCE
Sbjct: 907 RCIAGFHGDPRLPYGAQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCE 966
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
CA G +G P G C+ C CSGNI+P DP +CD G CL+C+++T G C
Sbjct: 967 ACAPGQFGDPS----RPGGRCQLCECSGNIDPMDPDACDPHPGQCLRCLHHTEGPHCAHS 1022
Query: 1914 APGFYGDAIFSKNCTACICDEFG----------MADCDSTTGTCVCRPGVIGEKCDRCAP 1963
PGF+G A ++C C C+ G CD ++G C C P V DRCAP
Sbjct: 1023 KPGFHGQAA-RQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQALAVDRCAP 1081
Query: 1964 DHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+ W L +G GC PC C E C++ GQC C G G+ C +C W C
Sbjct: 1082 NFWNLTSGHGCQPCACLPSPEEGPTCNEFTGQCHCLCGFGGRTCSECQELHWGDPGLQCH 1141
Query: 2023 HCNCNT-GYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFS 2081
C+C++ G TG C C PGV G +CD+C + I C C +C
Sbjct: 1142 ACDCDSRGIDTPQCHRFTGHCTCRPGVSGVRCDQCARGFSGI-FPACHPCHACFGDWDRV 1200
Query: 2082 VEDLSA 2087
V+DL+A
Sbjct: 1201 VQDLAA 1206
Score = 248 bits (607), Expect = 3e-64
Identities = 146/467 (31%), Positives = 221/467 (47%), Gaps = 48/467 (10%)
Query: 50 YAVDDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDY 109
+A R WWQS G+ V + +DL EFH ++ + + RP ++E+S D+
Sbjct: 115 FAPQRRAAWWQS---QNGIP--AVTIQLDLEAEFHFTHLIMTF-KTFRPAAMLVERSADF 168
Query: 110 GKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR 169
G+T+ ++YFS C F L P D V+C + YS+I P +GE+ +L+
Sbjct: 169 GRTWHVYRYFS---YHCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPA 225
Query: 170 -PSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIG 228
P + Y SS +Q + TN+R+ L R L +L+ R+ + +Y+Y++ ++ +
Sbjct: 226 IPIPDPY--SSRIQNLLKITNLRVNLTRLHTLGDNLLDPRRE---IREKYYYALYELVVR 280
Query: 229 GRCMCNGHADTCEPAD--PAGNLNIL--VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
G C C GHA C PA PA ++ C C+HNT G C +C + WR +++
Sbjct: 281 GNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGH 340
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
+C C+ H HT C +D +++ + GG C CQHNT +C CRP +
Sbjct: 341 SHACRKCDRHGHTHSCHFD-------MAVYLGSGNVSGGVCDGCQHNTAWRHCELCRPFF 393
Query: 345 YRPYGKRWDELDVCQPCQCDPHFST--GNCEEE--------SGRCECRPEFQPPDCSSCA 394
YR K + VC+ C CDP S G C+ SG+C C+ C C
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
Query: 395 YGYF-----DYPNCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE 447
G+F D C+ C CN GT C P G C CK G+ C+ C G++
Sbjct: 454 DGFFGLSISDPSGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS 513
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY 489
C+ C+C+ G++ CD+ TG C C+ GR C Q Q GY+
Sbjct: 514 LDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 221 bits (541), Expect = 3e-56
Identities = 135/425 (31%), Positives = 191/425 (44%), Gaps = 48/425 (11%)
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS---PECKNCECNTV 456
Y PC CN G+ C P G C CK G+ C+ C GYY C+ C+C+
Sbjct: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYYGFGPTGCQACQCSPR 836
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC 516
G++S +C++ +G C C++ G C+ CQ G + +P+C+PC C+ E C+ +G C
Sbjct: 837 GALSSLCERTSGQCLCRTGAFGLRCDACQRGQWGFPSCRPCVCNGHADE---CNTHTGAC 893
Query: 517 I-CKAGFGGPRCDQCLSGYYMQV-LGRERQCVPCNC-DPTGST---STSCSADG-----K 565
+ C+ GG C++C++G++ L QC PC C + GS +TSC D
Sbjct: 894 LGCRDLTGGEHCERCIAGFHGDPRLPYGAQCRPCPCPEGPGSQRHFATSCHQDEYSQQIV 953
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPD-----CLSCNCDVSGSIG----STCDDN-GLC-HCK 614
C+C + G +C+ C+PG + P C C C SG+I CD + G C C
Sbjct: 954 CHCRAGYTGLRCEACAPGQFGDPSRPGGRCQLCEC--SGNIDPMDPDACDPHPGQCLRCL 1011
Query: 615 SNFDGAKCDTCREQFYNYPA---CEECNCDPRGVT----ASFAGCGSVPAGELCQCKDRV 667
+ +G C + F+ A C C C+ G S C P+ C C V
Sbjct: 1012 HHTEGPHCAHSKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
Q + C P +WNL + GC+ C C + CN +GQC C G R C +
Sbjct: 1072 QALAVDRCAPNFWNLT--SGHGCQPCAC--LPSPEEGPTCNEFTGQCHCLCGFGGRTCSE 1127
Query: 728 CLDGFYRLQTNDV-FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIR--AHY 784
C + L D C CDCD G C + TG C C V G RCDQ R +
Sbjct: 1128 CQE----LHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCTCRPGVSGVRCDQCARGFSGI 1183
Query: 785 FPTLH 789
FP H
Sbjct: 1184 FPACH 1188
Score = 180 bits (438), Expect = 9e-44
Identities = 119/412 (28%), Positives = 173/412 (41%), Gaps = 52/412 (12%)
Query: 360 PCQCDPHFS-TGNCEEESGRCECRPEFQPPDCSSCAYGYFDY--PNCKPCTCNLNGTEGE 416
PCQC+P S + C G+C C+P C +CA GY+ + C+ C C+ G
Sbjct: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYYGFGPTGCQACQCSPRGALSS 841
Query: 417 HCTPTDGLCPCKYNYAGKSCEICEDGYYS-PECKNCECNTVGSVSYVCDKLTGDCT-CKS 474
C T G C C+ G C+ C+ G + P C+ C CN G C+ TG C C+
Sbjct: 842 LCERTSGQCLCRTGAFGLRCDACQRGQWGFPSCRPCVCN--GHAD-ECNTHTGACLGCRD 898
Query: 475 KYSGRTCNQCQAGYYNYP------TCKPCNC-DTSGTE---PSIC--DDVSGQ--CICKA 520
G C +C AG++ P C+PC C + G++ + C D+ S Q C C+A
Sbjct: 899 LTGGEHCERCIAGFHGDPRLPYGAQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD---GKC-NCLTNFGGAQ 576
G+ G RC+ C G + +C C C + D G+C CL + G
Sbjct: 959 GYTGLRCEACAPGQFGDPSRPGGRCQLCECSGNIDPMDPDACDPHPGQCLRCLHHTEGPH 1018
Query: 577 CDQCSPGYY---KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC---------DT 624
C PG++ C C C++ G+ C CHC + C D
Sbjct: 1019 CAHSKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQALAVDR 1078
Query: 625 CREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C F+N + C+ C C P C G+ C C GR C++C+ L+W
Sbjct: 1079 CAPNFWNLTSGHGCQPCACLPS--PEEGPTCNEF-TGQ-CHCLCGFGGRTCSECQELHWG 1134
Query: 682 LQEYNP-FGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGF 732
+P C C+C+ G C+ +G C C+ V +CDQC GF
Sbjct: 1135 ----DPGLQCHACDCDSRGI--DTPQCHRFTGHCTCRPGVSGVRCDQCARGF 1180
Score = 180 bits (438), Expect = 9e-44
Identities = 117/394 (29%), Positives = 164/394 (41%), Gaps = 56/394 (14%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN-CEEESGRCE 380
GG+CL C+ G C+ C P YY +G CQ CQC P + + CE SG+C
Sbjct: 799 GGQCL-CKPGVVGRRCDTCAPGYYG-FGPTG-----CQACQCSPRGALSSLCERTSGQCL 851
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEIC 439
CR C +C G + +P+C+PC CN + E C G C C+ G+ CE C
Sbjct: 852 CRTGAFGLRCDACQRGQWGFPSCRPCVCNGHADE---CNTHTGACLGCRDLTGGEHCERC 908
Query: 440 EDGY-------YSPECKNCEC-NTVGSVSYVCDKLTGD-------CTCKSKYSGRTCNQC 484
G+ Y +C+ C C GS + D C C++ Y+G C C
Sbjct: 909 IAGFHGDPRLPYGAQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEAC 968
Query: 485 QAGYYNYPT-----CKPCNC--DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYM 536
G + P+ C+ C C + +P CD GQC+ C GP C G++
Sbjct: 969 APGQFGDPSRPGGRCQLCECSGNIDPMDPDACDPHPGQCLRCLHHTEGPHCAHSKPGFHG 1028
Query: 537 QVLGRERQCVPCNCDPTGSTSTSC---------SADGKCNCLTNFGGAQCDQCSPGYYKY 587
Q + C C C+ G+ C + G+C CL N D+C+P ++
Sbjct: 1029 Q--AARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQALAVDRCAPNFWNL 1086
Query: 588 PD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPA--CEECNCD 641
C C C S G TC++ G CHC F G C C+E + P C C+CD
Sbjct: 1087 TSGHGCQPCACLPSPEEGPTCNEFTGQCHCLCGFGGRTCSECQELHWGDPGLQCHACDCD 1146
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDC 675
RG+ C C C+ V G C+ C
Sbjct: 1147 SRGIDT--PQCHRFTGH--CTCRPGVSGVRCDQC 1176
Score = 166 bits (404), Expect = 1e-39
Identities = 98/292 (33%), Positives = 132/292 (45%), Gaps = 39/292 (13%)
Query: 540 GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------- 588
G +C P P G C C N G C+QC Y P
Sbjct: 287 GHASECAPA---PGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA 343
Query: 589 --DC------LSCNCDVSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA----- 634
C SC+ D++ +GS G+C C+ N C+ CR FY P
Sbjct: 344 CRKCDRHGHTHSCHFDMAVYLGSGNVSGGVCDGCQHNTAWRHCELCRPFFYRDPTKDLRD 403
Query: 635 ---CEECNCDPRGVTASFAGCGSV--PAGEL----CQCKDRVQGRICNDCKPLYWNLQEY 685
C C+CDP G + C S PA L C+CK+ V G C C+ ++ L
Sbjct: 404 PAVCRSCDCDPMG-SQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSIS 462
Query: 686 NPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE 745
+P GC +C CN GT+ C+ SG C CK+ V R CD+CL G + L D+ GC
Sbjct: 463 DPSGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSL-DLLGCRP 521
Query: 746 CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQFQYEVED 797
CDCD+GG++D CD+ TGQCHC + GRRC+Q ++ P L +E E+
Sbjct: 522 CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEN 573
Score = 151 bits (365), Expect = 6e-35
Identities = 113/368 (30%), Positives = 134/368 (36%), Gaps = 54/368 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGH---SDQCDVNTGICLNCADNTIGD 1791
+C C G C+ CA G+Y C CQC+ S C+ +G CL C G
Sbjct: 801 QCLCKPGVVGRRCDTCAPGYYGFGPTGCQACQCSPRGALSSLCERTSGQCL-CRTGAFGL 859
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C+ C G G + C C C N A C+ L C+ GG
Sbjct: 860 RCDACQRGQWGFPS------CRPCVC------NGHADECNTHTGACL---GCRDLTGGEH 904
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC----------LKC 1901
CE C AG++G P L G C+PC C P+ PGS C C
Sbjct: 905 CERCIAGFHGDPR---LPYGAQCRPCPC-----PEGPGSQRHFATSCHQDEYSQQIVCHC 956
Query: 1902 VNNTAGAACNLCAPGFYGD-AIFSKNCTACIC----DEFGMADCDSTTGTCV-CRPGVIG 1955
G C CAPG +GD + C C C D CD G C+ C G
Sbjct: 957 RAGYTGLRCEACAPGQFGDPSRPGGRCQLCECSGNIDPMDPDACDPHPGQCLRCLHHTEG 1016
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ---------CDDDNGQCRCAKGVTGKQC 2006
C P G C C C + + Q CD +GQC C V
Sbjct: 1017 PHCAHSKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQALAV 1076
Query: 2007 DQCAAGFWNYTK-DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIP 2064
D+CA FWN T GC C C G CN TGQC CL G G C C E P
Sbjct: 1077 DRCAPNFWNLTSGHGCQPCACLPSPEEGPTCNEFTGQCHCLCGFGGRTCSECQELHWGDP 1136
Query: 2065 QEGCLECD 2072
C CD
Sbjct: 1137 GLQCHACD 1144
Score = 141 bits (341), Expect = 5e-32
Identities = 99/346 (28%), Positives = 140/346 (40%), Gaps = 58/346 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C+CNGHAD C N + C C+ T G C +C +GF R+ C
Sbjct: 877 CVCNGHADEC-------NTHTGACLGCRDLTGGEHCERCIAGFHGDP-RLPYG---AQCR 925
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY---- 345
PC C P + Y C +C+ G+ C C P +
Sbjct: 926 PC-------PCPEGPGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGQFGDPS 977
Query: 346 RPYGKRWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFDY 400
RP G+ CQ C+C DP C+ G+C C + P C+ G+
Sbjct: 978 RPGGR-------CQLCECSGNIDP-MDPDACDPHPGQCLRCLHHTEGPHCAHSKPGFHGQ 1029
Query: 401 ---PNCKPCTCNLNGTEGE--------HCTPTDGLCPCKYNYAGKSCEICEDGYYS---- 445
+C CTCNL GT + HC P+ G CPC N + + C +++
Sbjct: 1030 AARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQALAVDRCAPNFWNLTSG 1089
Query: 446 PECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP--TCKPCNCDTSG 503
C+ C C C++ TG C C + GRTC++CQ ++ P C C+CD+ G
Sbjct: 1090 HGCQPCACLPSPEEGPTCNEFTGQCHCLCGFGGRTCSECQELHWGDPGLQCHACDCDSRG 1149
Query: 504 TEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
+ C +G C C+ G G RCDQC G+ G C PC+
Sbjct: 1150 IDTPQCHRFTGHCTCRPGVSGVRCDQCARGF----SGIFPACHPCH 1191
Score = 138 bits (335), Expect = 3e-31
Identities = 91/282 (32%), Positives = 126/282 (44%), Gaps = 36/282 (12%)
Query: 1765 CQCNGHSDQC-----------DVNTGICLNCADNTIGDHCEFCMSGYHG----DATVGTP 1809
C C GH+ +C + G C+ C NT G +CE C Y A G
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
Query: 1810 RDCLICACPMPYPSNNFALSCDL-SENGSLISCN-CQPGYGGARCEYCAAGYYGIPEDTD 1867
C C S +F ++ L S N S C+ CQ CE C +Y P D
Sbjct: 342 HACRKCDRHGHTHSCHFDMAVYLGSGNVSGGVCDGCQHNTAWRHCELCRPFFYRDPTK-D 400
Query: 1868 LHTGDYCKPCNCSGNINPQDPGSCDS--------INGDCLKCVNNTAGAACNLCAPGFYG 1919
L C+ C+C + QD G CDS ++G C +C + G C C GF+G
Sbjct: 401 LRDPAVCRSCDCDP-MGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFG 458
Query: 1920 DAIFSKN-CTACICDEFGMAD----CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG-LG 1973
+I + C C C+ G CD +G+C C+ V G CDRC P HWGL+ LG
Sbjct: 459 LSISDPSGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSLDLLG 518
Query: 1974 CTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
C PC+C + QCD+ GQC C + + G++C+Q G++
Sbjct: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 133 bits (321), Expect = 1e-29
Identities = 89/284 (31%), Positives = 121/284 (42%), Gaps = 35/284 (12%)
Query: 1273 VWLDYVLVIEASDFTDAVLTEANILDYTREFIEQCASYNYYISPNETGLCREAMFSITSE 1332
V L VLV+E DA E + R + SP+E C + S+++
Sbjct: 719 VLLPRVLVLEMFSGGDAAALERQAT-FERYQCHEEGLVPSKTSPSEA--CAPLLISLSTL 775
Query: 1333 YNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--PNCRPCHCPS 1390
+GA PC C+ GS ECN GGQC CKP V+GR C C GYYGF C+ C C
Sbjct: 776 IYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYYGFGPTGCQACQCSP 835
Query: 1391 ----TAICD-DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
+++C+ +G C+C G CD C+ + F C C CN G+ +C
Sbjct: 836 RGALSSLCERTSGQCLCRTGAFGLRCDACQRGQWGFP---SCRPCVCN-----GHADECN 887
Query: 1446 ADSGKC-ACRENVRGRVCDHCVPGHYAFP------DCYQCTC------NRHGTTYDVCDQ 1492
+G C CR+ G C+ C+ G + P C C C RH T D+
Sbjct: 888 THTGACLGCRDLTGGEHCERCIAGFHGDPRLPYGAQCRPCPCPEGPGSQRHFATSCHQDE 947
Query: 1493 NTAQ--CYCKTNVRGQACDTCKEEYFNLQDDNPDG-CTKCFCFG 1533
+ Q C+C+ G C+ C F P G C C C G
Sbjct: 948 YSQQIVCHCRAGYTGLRCEACAPGQFG-DPSRPGGRCQLCECSG 990
Score = 132 bits (318), Expect = 3e-29
Identities = 81/249 (32%), Positives = 114/249 (45%), Gaps = 36/249 (14%)
Query: 1840 SCNCQPGYGGARCEYCAAGYYGIP----EDTDLHTGDYCKPCNCSGNINPQD------PG 1889
+C C+ G CE C Y +P ED H C+ C+ G+ + G
Sbjct: 309 ACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA---CRKCDRHGHTHSCHFDMAVYLG 365
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN----CTACICDEFGMAD---CDS 1942
S + G C C +NTA C LC P FY D C +C CD G D CDS
Sbjct: 366 SGNVSGGVCDGCQHNTAWRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDS 425
Query: 1943 --------TTGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNC---GIASESTQCD 1989
+G C C+ V+G +C +C +GL+ GC C C G ST CD
Sbjct: 426 HDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDPSGCRRCQCNARGTVPGSTPCD 485
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKD--GCDHCNCNTGYSVGFMCN-ATGQCECLP 2046
++G C C + VTG+ CD+C G W + D GC C+C+ G ++ C+ TGQC C
Sbjct: 486 PNSGSCYCKRLVTGRGCDRCLPGHWGLSLDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQ 545
Query: 2047 GVIGEKCDR 2055
++G +C++
Sbjct: 546 HMVGRRCEQ 554
Score = 127 bits (306), Expect = 9e-28
Identities = 87/291 (29%), Positives = 126/291 (43%), Gaps = 51/291 (17%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+ H +EC P G G C+ C+HNT G+NC +C+ +YR
Sbjct: 283 CFCYGHASECAPAPGAPAHA-----EGMVHGA--CI-CKHNTRGLNCEQCQD-FYRDLPW 333
Query: 351 RWDELDVCQPCQ-CDPHFSTGNCEEE-----------SGRCE-CRPEFQPPDCSSCAYGY 397
R E C+ CD H T +C + G C+ C+ C C +
Sbjct: 334 RPAEDGHSHACRKCDRHGHTHSCHFDMAVYLGSGNVSGGVCDGCQHNTAWRHCELCRPFF 393
Query: 398 FDYPN--------CKPCTCNLNGTE-GEHCTPTD--------GLCPCKYNYAGKSCEICE 440
+ P C+ C C+ G++ G C D G C CK + G C+ C
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
Query: 441 DGYYS-----PE-CKNCECNTVGSV--SYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP 492
DG++ P C+ C+CN G+V S CD +G C CK +GR C++C G++
Sbjct: 454 DGFFGLSISDPSGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS 513
Query: 493 T----CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL 539
C+PC+CD G CD+ +GQC C+ G RC+Q GY+ L
Sbjct: 514 LDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFL 564
Score = 123 bits (297), Expect = 1e-26
Identities = 81/260 (31%), Positives = 116/260 (44%), Gaps = 38/260 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC-----------DV 1776
C C RGL+CEQC + + LP S C C +GH+ C +V
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCDRHGHTHSCHFDMAVYLGSGNV 369
Query: 1777 NTGICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ G+C C NT HCE C ++ D T + P C C C P S + CD +
Sbjct: 370 SGGVCDGCQHNTAWRHCELCRPFFYRDPTKDLRDPAVCRSCDCD-PMGSQDGG-RCDSHD 427
Query: 1835 NGS--LIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS 1890
+ + L+S C C+ G RC+ C G++G+ + C+ C C N PGS
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL----SISDPSGCRRCQC--NARGTVPGS 481
Query: 1891 --CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CD +G C C G C+ C PG +G ++ C C CD G D CD TG
Sbjct: 482 TPCDPNSGSCY-CKRLVTGRGCDRCLPGHWGLSLDLLGCRPCDCDVGGALDPQCDEGTGQ 540
Query: 1947 CVCRPGVIGEKCDRCAPDHW 1966
C CR ++G +C++ P ++
Sbjct: 541 CHCRQHMVGRRCEQVQPGYF 560
Score = 116 bits (279), Expect = 2e-24
Identities = 75/253 (29%), Positives = 113/253 (44%), Gaps = 45/253 (17%)
Query: 423 GLCPCKYNYAGKSCEICEDGY-----------YSPECKNCE-------CNTVGSVSYVCD 464
G C CK+N G +CE C+D Y +S C+ C+ C+ +V
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCDRHGHTHSCHFDMAVYLGSG 367
Query: 465 KLTGD-CT-CKSKYSGRTCNQCQAGYYNYPT--------CKPCNCDTSGTEPS-ICDD-- 511
++G C C+ + R C C+ +Y PT C+ C+CD G++ CD
Sbjct: 368 NVSGGVCDGCQHNTAWRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 512 ------VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST--STSCSAD 563
VSGQC CK G RC QC G++ + C C C+ G+ ST C +
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDPSGCRRCQCNARGTVPGSTPCDPN 487
Query: 564 -GKCNCLTNFGGAQCDQCSPGYYKYP----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNF 617
G C C G CD+C PG++ C C+CDV G++ CD+ G CHC+ +
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSLDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 618 DGAKCDTCREQFY 630
G +C+ + ++
Sbjct: 548 VGRRCEQVQPGYF 560
Score = 112 bits (269), Expect = 3e-23
Identities = 61/193 (31%), Positives = 83/193 (43%), Gaps = 29/193 (15%)
Query: 1353 NTFGGQCP-CKPNVIGRTCSACRTGYYGFPN--------CRPCHCPSTAI-----CDDN- 1397
N GG C C+ N R C CR +Y P CR C C CD +
Sbjct: 368 NVSGGVCDGCQHNTAWRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 1398 --------GMCICPKNVEGENCDRCKPYTFNFDVQ--RGCDDCNCNPLGVVGNQLQCEAD 1447
G C C ++V G C +C+ F + GC C CN G V C+ +
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDPSGCRRCQCNARGTVPGSTPCDPN 487
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFP----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
SG C C+ V GR CD C+PGH+ C C C+ G CD+ T QC+C+ ++
Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSLDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 1504 RGQACDTCKEEYF 1516
G+ C+ + YF
Sbjct: 548 VGRRCEQVQPGYF 560
Score = 111 bits (268), Expect = 3e-23
Identities = 63/194 (32%), Positives = 96/194 (49%), Gaps = 34/194 (17%)
Query: 423 GLCP-CKYNYAGKSCEICEDGYYSPE---------CKNCECNTVGSVSYV-CDK------ 465
G+C C++N A + CE+C +Y C++C+C+ +GS CD
Sbjct: 372 GVCDGCQHNTAWRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPAL 431
Query: 466 --LTGDCTCKSKYSGRTCNQCQAGYYNY----PT-CKPCNCDTSGTEPSI--CDDVSGQC 516
++G C CK G C QC+ G++ P+ C+ C C+ GT P CD SG C
Sbjct: 432 GLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDPSGCRRCQCNARGTVPGSTPCDPNSGSC 491
Query: 517 ICKAGFGGPRCDQCLSGYY---MQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNF 572
CK G CD+CL G++ + +LG C PC+CD G+ C G+C+C +
Sbjct: 492 YCKRLVTGRGCDRCLPGHWGLSLDLLG----CRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 573 GGAQCDQCSPGYYK 586
G +C+Q PGY++
Sbjct: 548 VGRRCEQVQPGYFR 561
Score = 107 bits (257), Expect = 7e-22
Identities = 91/260 (35%), Positives = 115/260 (44%), Gaps = 49/260 (18%)
Query: 1825 NFALSCDLSENGSLIS--------CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
N AL C + GSL S C C+PG G RC+ CA GYYG TG C+
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYYGFGP-----TG--CQA 830
Query: 1877 CNCSGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDE 1934
C CS P+ S C+ +G CL C G C+ C G +G +C C+C+
Sbjct: 831 CQCS----PRGALSSLCERTSGQCL-CRTGAFGLRCDACQRGQWG----FPSCRPCVCN- 880
Query: 1935 FGMAD-CDSTTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC--GIASE--- 1984
G AD C++ TG C+ CR GE C+RC G L G C PC C G S+
Sbjct: 881 -GHADECNTHTGACLGCRDLTGGEHCERCIAGFHGDPRLPYGAQCRPCPCPEGPGSQRHF 939
Query: 1985 STQCDDDNGQ----CRCAKGVTGKQCDQCAAG-FWNYTKDG--CDHCNC--NTGYSVGFM 2035
+T C D C C G TG +C+ CA G F + ++ G C C C N
Sbjct: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGQFGDPSRPGGRCQLCECSGNIDPMDPDA 999
Query: 2036 CNA-TGQC-ECLPGVIGEKC 2053
C+ GQC CL G C
Sbjct: 1000 CDPHPGQCLRCLHHTEGPHC 1019
Score = 97.5 bits (232), Expect = 8e-19
Identities = 53/150 (35%), Positives = 73/150 (48%), Gaps = 12/150 (8%)
Query: 1913 CAPGFYG-DAIFSKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
CAP + C C+ G ++C+ G C+C+PGV+G +CD CAP ++G
Sbjct: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYYGFG 824
Query: 1970 TGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
GC C C + S+ C+ +GQC C G G +CD C G W + C C CN
Sbjct: 825 P-TGCQACQCSPRGALSSLCERTSGQCLCRTGAFGLRCDACQRGQWGF--PSCRPCVCN- 880
Query: 2029 GYSVGFMCNA-TGQC-ECLPGVIGEKCDRC 2056
G++ CN TG C C GE C+RC
Sbjct: 881 GHA--DECNTHTGACLGCRDLTGGEHCERC 908
Score = 93.9 bits (223), Expect = 1e-17
Identities = 64/210 (30%), Positives = 80/210 (38%), Gaps = 18/210 (8%)
Query: 1339 PCLCDFMGSTELEC--NTFGGQCP-CKPNVIGR----TCSACRTGYYGFPNCRPCHCPST 1391
P CD L C +T G C KP G+ +C C G N + C P
Sbjct: 997 PDACDPHPGQCLRCLHHTEGPHCAHSKPGFHGQAARQSCHRCTCNLLG-TNPQQCPSPDQ 1055
Query: 1392 AICD-DNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGK 1450
CD +G C C NV+ DRC P +N GC C C P G C +G+
Sbjct: 1056 CHCDPSSGQCPCLPNVQALAVDRCAPNFWNLTSGHGCQPCACLPSPEEGPT--CNEFTGQ 1113
Query: 1451 CACRENVRGRVCDHCVPGHYAFP--DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C C GR C C H+ P C+ C C+ G C + T C C+ V G C
Sbjct: 1114 CHCLCGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCTCRPGVSGVRC 1173
Query: 1509 DTCKEEYFNLQDDNPDGCTKCF-CFGKTTR 1537
D C + + C C CFG R
Sbjct: 1174 DQCARGFSGIF----PACHPCHACFGDWDR 1199
Score = 86.6 bits (205), Expect = 1e-15
Identities = 39/102 (38%), Positives = 55/102 (53%), Gaps = 4/102 (3%)
Query: 1959 DRCAPDHWGLNTGL--GCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN 2015
+ CAP L+T + G PC C S S++C+ GQC C GV G++CD CA G++
Sbjct: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYYG 822
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNAT-GQCECLPGVIGEKCDRC 2056
+ GC C C+ ++ +C T GQC C G G +CD C
Sbjct: 823 FGPTGCQACQCSPRGALSSLCERTSGQCLCRTGAFGLRCDAC 864
Score = 85.0 bits (201), Expect = 5e-15
Identities = 43/114 (37%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 675 CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYR 734
C PL +L G C CN G+L+S CN GQC+CK V R+CD C G+Y
Sbjct: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSS--ECNPHGGQCLCKPGVVGRRCDTCAPGYYG 822
Query: 735 LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY-FPT 787
GC C C G++ + C++T+GQC C + G RCD R + FP+
Sbjct: 823 FGPT---GCQACQCSPRGALSSLCERTSGQCLCRTGAFGLRCDACQRGQWGFPS 873
Score = 83.8 bits (198), Expect = 1e-14
Identities = 60/220 (27%), Positives = 88/220 (40%), Gaps = 27/220 (12%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICD 1395
GA C + G +C F P +P G + + + +G + CH
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCDRHG--HTHSCHFDMAVYLG 365
Query: 1396 DN----GMCI-CPKNVEGENCDRCKPYTFNFDVQ-----RGCDDCNCNPLGVV-GNQLQC 1444
G+C C N +C+ C+P+ + + C C+C+P+G G +
Sbjct: 366 SGNVSGGVCDGCQHNTAWRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDS 425
Query: 1445 EAD------SGKCACRENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTT--YDVCD 1491
D SG+C C+E+V G C C G + C +C CN GT CD
Sbjct: 426 HDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDPSGCRRCQCNARGTVPGSTPCD 485
Query: 1492 QNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
N+ CYCK V G+ CD C ++ L D GC C C
Sbjct: 486 PNSGSCYCKRLVTGRGCDRCLPGHWGLSLDLL-GCRPCDC 524
Score = 70.1 bits (164), Expect = 1e-10
Identities = 70/243 (28%), Positives = 98/243 (40%), Gaps = 49/243 (20%)
Query: 1877 CNCSGNIN-----PQDPGSCDS-INGDCLKCVNNTAGAACNLCAPGFYGDAIFSK----N 1926
C C G+ + P P + ++G C+ C +NT G C C FY D + +
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340
Query: 1927 CTACI-CDEFG------------MADCDSTTGTCV-CRPGVIGEKCDRCAPDHW-----G 1967
AC CD G + + + G C C+ C+ C P +
Sbjct: 341 SHACRKCDRHGHTHSCHFDMAVYLGSGNVSGGVCDGCQHNTAWRHCELCRPFFYRDPTKD 400
Query: 1968 LNTGLGCTPCNCGI--ASESTQCD--DD------NGQCRCAKGVTGKQCDQCAAGFWNYT 2017
L C C+C + + +CD DD +GQCRC + V G +C QC GF+ +
Sbjct: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLS 460
Query: 2018 ---KDGCDHCNCNTGYSV--GFMCNA-TGQCECLPGVIGEKCDRC-PERWVL-IPQEGCL 2069
GC C CN +V C+ +G C C V G CDRC P W L + GC
Sbjct: 461 ISDPSGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSLDLLGCR 520
Query: 2070 ECD 2072
CD
Sbjct: 521 PCD 523
Score = 66.5 bits (155), Expect = 2e-09
Identities = 35/109 (32%), Positives = 50/109 (45%), Gaps = 11/109 (10%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGST--ELECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
CR+ F ++ SG R C C+ G+ C+ G C CK V GR C C G++G
Sbjct: 452 CRDGFFGLSISDPSGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Query: 1380 FP----NCRPCHCPSTAI----CDD-NGMCICPKNVEGENCDRCKPYTF 1419
CRPC C CD+ G C C +++ G C++ +P F
Sbjct: 512 LSLDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 64.1 bits (149), Expect = 9e-09
Identities = 39/117 (33%), Positives = 51/117 (43%), Gaps = 10/117 (8%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C +++TS + G +PC C CN F GQC C GRTCS C+ ++G P
Sbjct: 1079 CAPNFWNLTSGH--GCQPCACLPSPEEGPTCNEFTGQCHCLCGFGGRTCSECQELHWGDP 1136
Query: 1382 --NCRPCHCPSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
C C C S I C G C C V G CD+C + ++ F C C
Sbjct: 1137 GLQCHACDCDSRGIDTPQCHRFTGHCTCRPGVSGVRCDQCARGFSGIFPACHPCHAC 1193
Score = 63.7 bits (148), Expect = 1e-08
Identities = 52/192 (27%), Positives = 76/192 (39%), Gaps = 33/192 (17%)
Query: 1378 YGFPN-CRPCH-CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN--CN 1433
YG + C P P+ A +G CIC N G NC++C+ + + + D + C
Sbjct: 286 YGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACR 345
Query: 1434 PLGVVGNQLQCEAD-----------SGKC-ACRENVRGRVCDHCVPGHYAFPD------- 1474
G+ C D G C C+ N R C+ C P Y P
Sbjct: 346 KCDRHGHTHSCHFDMAVYLGSGNVSGGVCDGCQHNTAWRHCELCRPFFYRDPTKDLRDPA 405
Query: 1475 -CYQCTCNRHGTTYDV-CDQN--------TAQCYCKTNVRGQACDTCKEEYFNLQDDNPD 1524
C C C+ G+ CD + + QC CK +V G C C++ +F L +P
Sbjct: 406 VCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDPS 465
Query: 1525 GCTKCFCFGKTT 1536
GC +C C + T
Sbjct: 466 GCRRCQCNARGT 477
Score = 56.8 bits (131), Expect = 1e-06
Identities = 41/135 (30%), Positives = 55/135 (40%), Gaps = 20/135 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCNGH-----SDQCDVNTGICLNCA 1785
+C+C G C+QC +G + L PSG C CQCN S CD N+G C C
Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDPSG-CRRCQCNARGTVPGSTPCDPNSGSCY-CK 494
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
G C+ C+ G+ G + C C C + CD C+C+
Sbjct: 495 RLVTGRGCDRCLPGHWGLSL--DLLGCRPCDCDV---GGALDPQCDEGTG----QCHCRQ 545
Query: 1846 GYGGARCEYCAAGYY 1860
G RCE GY+
Sbjct: 546 HMVGRRCEQVQPGYF 560
Score = 46.8 bits (106), Expect = 0.001
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 2019 DGCDHCNCNTGYSVGFMCNATG-QCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
+G C CN S+ CN G QC C PGV+G +CD C + GC C
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYYGFGPTGCQAC 831
Score = 41.9 bits (94), Expect = 0.042
Identities = 20/59 (33%), Positives = 26/59 (44%)
Query: 726 DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
+ C L T G C C+ GS+ + C+ GQC C V GRRCD +Y
Sbjct: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDTCAPGYY 821
>AK075536-1|BAC11679.1| 529|Homo sapiens protein ( Homo sapiens
cDNA PSEC0236 fis, clone HEMBA1007104, highly similar to
Laminin gamma-3 chain precursor. ).
Length = 529
Score = 275 bits (674), Expect = 2e-72
Identities = 146/427 (34%), Positives = 215/427 (50%), Gaps = 37/427 (8%)
Query: 34 CDICDANNEAKKHPPEYAVD----DRRTWWQSPPLSRGMKY-NEVNLTIDLGQEFHVAYV 88
C CDA + + H Y D D TWWQSP ++ G++Y VN+T+ LG+ + + YV
Sbjct: 74 CQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYV 133
Query: 89 FVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVI 145
+K S RPE + + K + ++P+Q++S S C++ +G+ + L+P +
Sbjct: 134 RLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQKTYGRPEGQCLRPGEDERVAF 189
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLM 205
C++E+S I PL G + S L RPS+ + S LQEW +T + + L R +
Sbjct: 190 CTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF 249
Query: 206 SVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
+DP V + Y+Y++ D S+GGRC CNGHA C P D AG L CRCQHNT G C
Sbjct: 250 ----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGP-DVAGQL---ACRCQHNTTGTDC 301
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
+C F+ + W C PCNC + ECT+D E+ G GG+C
Sbjct: 302 ERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS------TGH---GGRC 352
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
+C+ +T G +C +C+ +Y WD CQPC C S +++G C C+P
Sbjct: 353 HHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTV 407
Query: 386 QPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGY 443
C C G+ C+PCTCN G+ + C P G CPCK N G C+ C G
Sbjct: 408 TGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGT 466
Query: 444 YSPECKN 450
++ + N
Sbjct: 467 FNLQPHN 473
Score = 120 bits (289), Expect = 1e-25
Identities = 71/200 (35%), Positives = 84/200 (42%), Gaps = 13/200 (6%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-EDTDLHTGDYCKPCNCSGN 1882
N A C G L +C CQ G CE C + P C PCNCSG
Sbjct: 274 NGHASECGPDVAGQL-ACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGR 332
Query: 1883 INP----QDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTACICDEFGM 1937
++ G C C ++TAG C C FY D C C C G
Sbjct: 333 SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGS 390
Query: 1938 A--DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC 1995
CD T GTC C+P V G KCDRC P L+ G GC PC C A CD +G+C
Sbjct: 391 LHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEG-GCRPCTCNPAGSLDTCDPRSGRC 448
Query: 1996 RCAKGVTGKQCDQCAAGFWN 2015
C + V G CD+C G +N
Sbjct: 449 PCKENVEGNLCDRCRPGTFN 468
Score = 118 bits (285), Expect = 3e-25
Identities = 76/244 (31%), Positives = 112/244 (45%), Gaps = 38/244 (15%)
Query: 1324 EAMFSITSEYNSGARPCLCDFMGSTELECNT-FGGQ--CPCKPNVIGRTCSACRTGYYGF 1380
++ + S+++ G R C C+ S EC GQ C C+ N G C C +
Sbjct: 256 QSYYYAVSDFSVGGR-CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 1381 P----------NCRPCHCPSTAI-CD----------DNGMCI-CPKNVEGENCDRCKPYT 1418
P C PC+C + C G C C + G +C+RC+
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD--CY 1476
+++D + C C+C G + LQC+ D+G CAC+ V G CD C+PG ++ + C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 428
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTT 1536
CTCN G+ D CD + +C CK NV G CD C+ FNLQ NP + C + +
Sbjct: 429 PCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPSSRS---CRSRAS 484
Query: 1537 RCSS 1540
R +S
Sbjct: 485 RVTS 488
Score = 118 bits (284), Expect = 4e-25
Identities = 66/209 (31%), Positives = 95/209 (45%), Gaps = 25/209 (11%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGR-----ERQCVPCNCD 551
C +G DV+GQ C C+ G C++CL + + R +C+PCNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 552 PTGSTST-------SCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGS 600
T S G+C+ C + G C++C +Y + C C+C +GS
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGS 390
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNCDPRGVTASFAGCGSVPAG 658
+ CDD G C CK G KCD C F++ C C C+P G S C P
Sbjct: 391 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAG---SLDTCD--PRS 445
Query: 659 ELCQCKDRVQGRICNDCKPLYWNLQEYNP 687
C CK+ V+G +C+ C+P +NLQ +NP
Sbjct: 446 GRCPCKENVEGNLCDRCRPGTFNLQPHNP 474
Score = 109 bits (263), Expect = 1e-22
Identities = 67/222 (30%), Positives = 92/222 (41%), Gaps = 34/222 (15%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P++ G CQHNT G +C +C P + RP+
Sbjct: 271 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERCLPFFQDRPWA 314
Query: 350 KRWDEL-DVCQPCQCDPHFSTGNCEEE-------SGRCE-CRPEFQPPDCSSCAYGYFDY 400
+ E C PC C + E GRC CR P C C ++ +
Sbjct: 315 RGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW 374
Query: 401 -PN--CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE---CKNCECN 454
P C+PC C G+ C T G C CK G C+ C G++S C+ C CN
Sbjct: 375 DPRMPCQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN 433
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
GS+ CD +G C CK G C++C+ G +N P
Sbjct: 434 PAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNP 474
Score = 106 bits (254), Expect = 2e-21
Identities = 66/220 (30%), Positives = 96/220 (43%), Gaps = 25/220 (11%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC----EDG 442
P S Y D+ C CN + +E C C++N G CE C +D
Sbjct: 252 PKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDR 311
Query: 443 YYSP-------ECKNCECN------TVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGY 488
++ EC C C+ T + G C C+ +G C +CQ +
Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
Query: 489 YNYPT---CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
Y++ C+PC+C ++G+ CDD +G C CK G +CD+CL G++ E C
Sbjct: 372 YHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSL---SEGGC 427
Query: 546 VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
PC C+P GS T G+C C N G CD+C PG +
Sbjct: 428 RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTF 467
Score = 104 bits (249), Expect = 7e-21
Identities = 69/214 (32%), Positives = 92/214 (42%), Gaps = 26/214 (12%)
Query: 1859 YYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFY 1918
YY + +D G CK C+G+ + P + +C +NT G C C P F
Sbjct: 259 YYAV---SDFSVGGRCK---CNGHASECGPDVAGQL---ACRCQHNTTGTDCERCLPFFQ 309
Query: 1919 ------GDAIFSKNCTACICD------EFGMADCDSTT--GTCV-CRPGVIGEKCDRCAP 1963
G A + C C C F ST G C CR G C+RC
Sbjct: 310 DRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE 369
Query: 1964 DHWGLNTGLGCTPCNCGIA-SESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+ + + + C PC+C A S QCDD G C C VTG +CD+C GF + ++ GC
Sbjct: 370 NFYHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCR 428
Query: 2023 HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRC 2056
C CN S+ +G+C C V G CDRC
Sbjct: 429 PCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRC 462
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 593 CNCDVSGS-IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C C+ S G C C+ N G C+ C F + P C CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 642 PRGVTASFAG--CGSVPAGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA 698
R +F S G C C+D G C C+ +++ P C+ C+C A
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSA 388
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNC 758
G+L+ C+ +G C CK V +CD+CL GF+ L GC C C+ GS+D C
Sbjct: 389 GSLHL--QCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLD-TC 441
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
D +G+C C VEG CD+
Sbjct: 442 DPRSGRCPCKENVEGNLCDR 461
Score = 99.5 bits (237), Expect = 2e-19
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 33/214 (15%)
Query: 548 CNCDPTGST-STSCSADGKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ S + C C N G C++C P + P +CL CNC
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 597 -------VSGSIGSTCDDNGLCH-CKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGV 645
+ + G CH C+ + G C+ C+E FY++ C+ C+C G
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAG- 389
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG 705
+ C C CK V G C+ C P + +L E GC C CN AG+L++
Sbjct: 390 -SLHLQCDDTGT---CACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLDT-- 440
Query: 706 ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND 739
C+ +SG+C CK++V CD+C G + LQ ++
Sbjct: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHN 473
Score = 98.7 bits (235), Expect = 3e-19
Identities = 67/228 (29%), Positives = 93/228 (40%), Gaps = 25/228 (10%)
Query: 1752 EGHYRLPSGFCVP--CQCNGHSDQC--DVNTGICLNCADNTIGDHCEFCMSGYH----GD 1803
+ +Y S F V C+CNGH+ +C DV + C NT G CE C+ +
Sbjct: 256 QSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWAR 315
Query: 1804 ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP 1863
T +CL C C F S +C+ G CE C +Y
Sbjct: 316 GTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD 375
Query: 1864 EDTDLHTGDYCKPCNC--SGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDA 1921
C+PC+C +G+++ Q CD G C C G C+ C PGF+ +
Sbjct: 376 PRMP------CQPCDCQSAGSLHLQ----CDD-TGTCA-CKPTVTGWKCDRCLPGFH--S 421
Query: 1922 IFSKNCTACICDEFGMAD-CDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
+ C C C+ G D CD +G C C+ V G CDRC P + L
Sbjct: 422 LSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNL 469
Score = 84.6 bits (200), Expect = 6e-15
Identities = 59/202 (29%), Positives = 85/202 (42%), Gaps = 43/202 (21%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C+C G CE+C P + C+PC C+G S++C +
Sbjct: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
Query: 1779 GICLNCADNTIGDHCEFCMSG-YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGS 1837
G C +C D+T G HCE C YH D + C C C + + L CD + G
Sbjct: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRM----PCQPCDC---QSAGSLHLQCD--DTG- 399
Query: 1838 LISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP-GSCDSING 1896
+C C+P G +C+ C G++ + E C+PC C NP +CD +G
Sbjct: 400 --TCACKPTVTGWKCDRCLPGFHSLSEGG-------CRPCTC----NPAGSLDTCDPRSG 446
Query: 1897 DCLKCVNNTAGAACNLCAPGFY 1918
C C N G C+ C PG +
Sbjct: 447 RC-PCKENVEGNLCDRCRPGTF 467
Score = 82.6 bits (195), Expect = 2e-14
Identities = 47/147 (31%), Positives = 65/147 (44%), Gaps = 17/147 (11%)
Query: 1947 CVCRPGVIGEKCDRCAP---DH-WGLNTGLG---CTPCNCGIASESTQCDDD-------N 1992
C C+ G C+RC P D W T C PCNC SE D +
Sbjct: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
Query: 1993 GQCR-CAKGVTGKQCDQCAAGFWNYT-KDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
G+C C G C++C F+++ + C C+C + S+ C+ TG C C P V G
Sbjct: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTG 409
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDA 2077
KCDRC + + + GC C +C A
Sbjct: 410 WKCDRCLPGFHSLSEGGCRPC-TCNPA 435
Score = 55.2 bits (127), Expect = 4e-06
Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 1316 PNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
P TG C + S G RPC C+ GS + C+ G+CPCK NV G C CR
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
Query: 1375 TGYYGFPNCRPCHCPSTAIC 1394
G + N +P H PS+ C
Sbjct: 464 PGTF---NLQP-HNPSSRSC 479
>S76436-1|AAB21121.2| 507|Homo sapiens heparan sulfate proteoglycan
core protein protein.
Length = 507
Score = 270 bits (662), Expect = 6e-71
Identities = 156/445 (35%), Positives = 212/445 (47%), Gaps = 18/445 (4%)
Query: 1497 CYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYP 1556
C CK NV G+ C+ C + F+L NPDGC KCFC G + C+SS ++ A + + P
Sbjct: 3 CRCKNNVVGRLCNECADRSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASE-EP 61
Query: 1557 VDVLINNTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYF-GAPEYYLGKRLTSYGGY 1615
+ N H + + T +G + YF P +LG ++TSYGG
Sbjct: 62 GHFSLTNAAS--THTTNEGIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGE 119
Query: 1616 LTYTVHYTTR-GDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLD 1674
L +TV ++ G P V++ G N L H+ ++P G P T V E+ + D
Sbjct: 120 LRFTVTQRSQPGSTPLHGQPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPD 179
Query: 1675 GAPVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVE 1734
G P TR+ + AL I L IRASY + E+ LS + +++ V G + A VE
Sbjct: 180 GQPATREHLLMALAGIDTLLIRASYAQQPAESRLSGISMDVAVPEETGQD----PALEVE 235
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
+C CP Y G SC+ C G+ R PSG C C C+GHS+ C+ TG C C +T G
Sbjct: 236 QCSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 295
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
CE C GY+GDA GTP+DC +C C + AL+C L +G C PG+ G
Sbjct: 296 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACSPGHSGR 355
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS--CDSINGDCLKCVNNTAGA 1908
CE CA GYYG P D P N +PQ S CD+ G C +C G
Sbjct: 356 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA-GQC-QCKAQVEGL 413
Query: 1909 ACNLCAP-GFYGDAIFSKNCTACIC 1932
C+ C P F+ A C C C
Sbjct: 414 TCSHCRPHHFHLSASNPDGCLPCFC 438
Score = 126 bits (303), Expect = 2e-27
Identities = 76/218 (34%), Positives = 98/218 (44%), Gaps = 33/218 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPS-TAICD-DNGMCI-CPKNVEG 1408
QC C P +G +C C TGY P+ C C C + C+ + G C C + EG
Sbjct: 236 QCSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 295
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQ-LQCEADSG---KC-ACRENVRG 1459
C++C+P + D QRG C C C G L C D+ C AC G
Sbjct: 296 PRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACSPGHSG 354
Query: 1460 RVCDHCVPGHYAFPD----CYQ---------CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
R C+ C PG+Y P C + C C+ G+ CD QC CK V G
Sbjct: 355 RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGL 413
Query: 1507 ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYT 1544
C C+ +F+L NPDGC CFC G T +C+SS YT
Sbjct: 414 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYT 451
Score = 111 bits (268), Expect = 3e-23
Identities = 67/202 (33%), Positives = 88/202 (43%), Gaps = 32/202 (15%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C+C Y G +C C GY P TC+ C+C C+ +G C C+
Sbjct: 237 CSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHS---EACEPETGACQGCQHHT 293
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNC--DPT-GSTSTSC--SADGK--CN-CLTNFG 573
GPRC+QC GYY G + C C C DP G + +C DG C+ C
Sbjct: 294 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACSPGHS 353
Query: 574 GAQCDQCSPGYYKYPD----C---------LSCNCDVSGSIGSTCDDNGLCHCKSNFDGA 620
G C++C+PGYY P C + CNCD GS+ S CD G C CK+ +G
Sbjct: 354 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 413
Query: 621 KCDTCREQFYNYPACEECNCDP 642
C CR ++ A C P
Sbjct: 414 TCSHCRPHHFHLSASNPDGCLP 435
Score = 103 bits (247), Expect = 1e-20
Identities = 69/205 (33%), Positives = 85/205 (41%), Gaps = 37/205 (18%)
Query: 425 CPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDCT-CKSKY 476
C C Y G SC+ C+ GY Y C+ C C+ S C+ TG C C+
Sbjct: 237 CSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGCQHHT 293
Query: 477 SGRTCNQCQAGYY------NYPTCKPCNC---DTSGTEPSICD-DVSGQCICKA---GFG 523
G C QCQ GYY C+ C C +G C D G C A G
Sbjct: 294 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACSPGHS 353
Query: 524 GPRCDQCLSGYY-----MQVLGRERQC---VPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
G C++C GYY Q R+ Q + CNCDP GS S+ C A G+C C G
Sbjct: 354 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 413
Query: 576 QCDQCSPGYY----KYPD-CLSCNC 595
C C P ++ PD CL C C
Sbjct: 414 TCSHCRPHHFHLSASNPDGCLPCFC 438
Score = 101 bits (242), Expect = 5e-20
Identities = 72/226 (31%), Positives = 103/226 (45%), Gaps = 41/226 (18%)
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTST 558
+ +G +P++ +V QC C G+ GP C C +GY G C C+C S
Sbjct: 224 EETGQDPAL--EVE-QCSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSE 277
Query: 559 SCSAD-GKCN-CLTNFGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC-- 605
+C + G C C + G +C+QC PGYY DC C C +G TC
Sbjct: 278 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFL 337
Query: 606 --DDNGLCH-CKSNFDGAKCDTCREQFYNYPA----CEE---------CNCDPRGVTASF 649
D + C C G C+ C +Y P+ C+ CNCDP+G +S
Sbjct: 338 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS- 396
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C + AG+ CQCK +V+G C+ C+P +++L NP GC C C
Sbjct: 397 -QCDA--AGQ-CQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 438
Score = 99.1 bits (236), Expect = 3e-19
Identities = 66/210 (31%), Positives = 89/210 (42%), Gaps = 38/210 (18%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLCP-C 427
E +C C P + P C C GY P+ C+ C+C+ E C P G C C
Sbjct: 233 EVEQCSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGC 289
Query: 428 KYNYAGKSCEICEDGYYS-------PECKNCEC---NTVGSVSYVCDKLT-GDCTCKS-- 474
+++ G CE C+ GYY +C+ C C G + C T G TC +
Sbjct: 290 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACS 349
Query: 475 -KYSGRTCNQCQAGYYNYPT----CK---------PCNCDTSGTEPSICDDVSGQCICKA 520
+SGR C +C GYY P+ C+ CNCD G+ S C D +GQC CKA
Sbjct: 350 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAAGQCQCKA 408
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
G C C ++ C+PC C
Sbjct: 409 QVEGLTCSHCRPHHFHLSASNPDGCLPCFC 438
Score = 84.6 bits (200), Expect = 6e-15
Identities = 63/222 (28%), Positives = 91/222 (40%), Gaps = 38/222 (17%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCE-CRPEF 385
+C G +C C Y R + L C+ C C H CE E+G C+ C+
Sbjct: 238 SCPPGYLGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGHSEA--CEPETGACQGCQHHT 293
Query: 386 QPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGEHCTP----TDG--LCP-CKYNYA 432
+ P C C GY+ +C+ C C + G+ TDG C C ++
Sbjct: 294 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACSPGHS 353
Query: 433 GKSCEICEDGYY-SPE----CKN---------CECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G+ CE C GYY +P C+ C C+ GSVS CD G C CK++ G
Sbjct: 354 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEG 412
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
TC+ C+ +++ P C P C ++ QC A
Sbjct: 413 LTCSHCRPHHFHLSASNPDGC-----LPCFCMGITQQCASSA 449
Score = 83.8 bits (198), Expect = 1e-14
Identities = 60/215 (27%), Positives = 91/215 (42%), Gaps = 29/215 (13%)
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDS 1942
P++ G ++ + C G +C C G+ ++ C C C A C+
Sbjct: 223 PEETGQDPALEVEQCSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA-CEP 281
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC------GIASESTQCDDD- 1991
TG C C+ G +C++C P ++G T C C C G A+ + D D
Sbjct: 282 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDG 341
Query: 1992 NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---------CNCNTGYSVGFMCNAT 2039
+ C C+ G +G+ C++CA G++ G C CNC+ SV C+A
Sbjct: 342 HPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA 401
Query: 2040 GQCECLPGVIGEKCDRC-PERWVLIPQ--EGCLEC 2071
GQC+C V G C C P + L +GCL C
Sbjct: 402 GQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 436
Score = 80.2 bits (189), Expect = 1e-13
Identities = 54/190 (28%), Positives = 85/190 (44%), Gaps = 31/190 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 269 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 317
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + L+ ++ +G C C G +C +C P YY P
Sbjct: 318 QLCPCYG-------DPAAGQAALTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNP 368
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----- 398
+ + D P C CDP S + + +G+C+C+ + + CS C +F
Sbjct: 369 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSAS 428
Query: 399 DYPNCKPCTC 408
+ C PC C
Sbjct: 429 NPDGCLPCFC 438
Score = 79.0 bits (186), Expect = 3e-13
Identities = 69/248 (27%), Positives = 93/248 (37%), Gaps = 52/248 (20%)
Query: 244 DPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYD 303
DPA L + C C GP C C +G+ R +CE C+CH H+ C +
Sbjct: 229 DPA--LEVEQCSCPPGYLGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--E 280
Query: 304 PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC 363
PE G C CQH+TEG C +C+P YY +R D CQ C C
Sbjct: 281 PET----------------GACQGCQHHTEGPRCEQCQPGYYGD-AQRGTPQD-CQLCPC 322
Query: 364 --DPHFSTG--NC---EEESGRCE-CRPEFQPPDCSSCAYGYFDYPN----CK------- 404
DP C + C+ C P C CA GY+ P+ C+
Sbjct: 323 YGDPAAGQAALTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 382
Query: 405 --PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
C C+ G+ C G C CK G +C C ++ N + G +
Sbjct: 383 PIGCNCDPQGSVSSQCDAA-GQCQCKAQVEGLTCSHCRPHHFHLSASNPD----GCLPCF 437
Query: 463 CDKLTGDC 470
C +T C
Sbjct: 438 CMGITQQC 445
Score = 74.5 bits (175), Expect = 6e-12
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPDCL---SCN-CDVSGSIGSTCDDNGLCH-CKSNFDG 619
+C+C + G C C GY + P L +C C G + + G C C+ + +G
Sbjct: 236 QCSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 295
Query: 620 AKCDTCREQFYNYPA------CEECNC--DPRGVTASFAGCGSVPAGELCQ-CKDRVQGR 670
+C+ C+ +Y C+ C C DP A+ C C GR
Sbjct: 296 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACSPGHSGR 355
Query: 671 ICNDCKPLYW-NLQEYNPF-------GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C C P Y+ N + P G CNC+ G+++S C+ +GQC CK V
Sbjct: 356 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS--QCDA-AGQCQCKAQVEG 412
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDC 748
C C + L ++ GC C C
Sbjct: 413 LTCSHCRPHHFHLSASNPDGCLPCFC 438
Score = 72.5 bits (170), Expect = 3e-11
Identities = 55/197 (27%), Positives = 78/197 (39%), Gaps = 32/197 (16%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQ-C 663
C C + G C C + P+ CE C+C P CQ C
Sbjct: 237 CSCPPGYLGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE-------PETGACQGC 289
Query: 664 KDRVQGRICNDCKPLYW-NLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCVCKQ-- 718
+ +G C C+P Y+ + Q P C+ C C + A +L G C
Sbjct: 290 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAALTCFLDTDGHPTCDACS 349
Query: 719 --HVGERQCDQCLDGFYR--------LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH 768
H G R C++C G+Y + + V G C+CD GS+ + CD GQC C
Sbjct: 350 PGHSG-RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCK 407
Query: 769 SRVEGRRCDQPIRAHYF 785
++VEG C R H+F
Sbjct: 408 AQVEGLTCSH-CRPHHF 423
Score = 48.0 bits (109), Expect = 6e-04
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK
Sbjct: 358 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQ 409
Query: 1365 VIGRTCSACRTGYYGF-----PNCRPCHC 1388
V G TCS CR ++ C PC C
Sbjct: 410 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 438
Score = 44.8 bits (101), Expect = 0.006
Identities = 16/35 (45%), Positives = 23/35 (65%)
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C+CK+ V GR+CN+C ++L NP GC +C C
Sbjct: 3 CRCKNNVVGRLCNECADRSFHLSTRNPDGCLKCFC 37
Score = 41.9 bits (94), Expect = 0.042
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCNGHSDQC 1774
+CQC GL+C C H+ L P G C+PC C G + QC
Sbjct: 403 QCQCKAQVEGLTCSHCRPHHFHLSASNPDG-CLPCFCMGITQQC 445
Score = 37.5 bits (83), Expect = 0.90
Identities = 14/35 (40%), Positives = 20/35 (57%)
Query: 714 CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C CK +V R C++C D + L T + GC +C C
Sbjct: 3 CRCKNNVVGRLCNECADRSFHLSTRNPDGCLKCFC 37
>L25541-1|AAA61834.1| 1170|Homo sapiens laminin S B3 chain protein.
Length = 1170
Score = 267 bits (655), Expect = 4e-70
Identities = 160/516 (31%), Positives = 241/516 (46%), Gaps = 53/516 (10%)
Query: 58 WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQ 117
WWQS N V+L +DL + F + V ++ P P ++E+S+D+GKT++ +Q
Sbjct: 94 WWQSQN-----DVNPVSLQLDLDRRFQLQEVMMEF-RGPMPAGMLIERSSDFGKTWRVYQ 147
Query: 118 YFSDSPQDCERYFGK-ESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
Y + DC F + +P + D S L G++ ++L+ D S
Sbjct: 148 YLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLM-DLVSGIPAT 203
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S +QE TN+R+ R L + P+ +Y++ + + G C C+GH
Sbjct: 204 QSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGH 255
Query: 237 ADTC--EPADPAGNLNILV---CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
AD C +P AG+ + V C CQHNT GP C +C + + WR ++ D C+ C
Sbjct: 256 ADRCAPKPGASAGSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRC 315
Query: 292 NCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKR 351
+C+ H+ C +DP + G Y GG C NC+ +TEG NC +C+ Y+R
Sbjct: 316 DCNGHSETCHFDPAVFAAS-----QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRPG 368
Query: 352 WDELDVCQPCQCDPHFSTGN--CEEESGRCECRPEFQPPDCSSCAYGY--FDYPN---CK 404
+ C C+CDP + C+ +G+C C+ Q C C G+ Y N C
Sbjct: 369 ASIQETCISCECDPDGAVAGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPRRCH 428
Query: 405 PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYY----SPECKNCECNTVGSVS 460
C CN+ G+ C G C C N G C+ C ++ C+ C C+ S+S
Sbjct: 429 RCDCNILGSREMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLS 488
Query: 461 YVCDKLTGDCTCKSKYSGRTCN-----QC-QAGYYNYPT-CKPCNCDTSGTEPSICDDVS 513
C++ TG C C+ + G C+ QC Y + T C+ C+CD GTE CD S
Sbjct: 489 PQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKAS 548
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
G+C+C+ G GPRCDQC GY R CV C+
Sbjct: 549 GRCLCRPGLTGPRCDQCQRGY----CNRYPVCVACH 580
Score = 171 bits (417), Expect = 3e-41
Identities = 105/338 (31%), Positives = 150/338 (44%), Gaps = 33/338 (9%)
Query: 1765 CQCNGHSDQCDVNTG------------ICLNCADNTIGDHCEFCMSGYHG----DATVGT 1808
C C+GH+D+C G +C+ C NT G +CE C Y+ A
Sbjct: 250 CFCHGHADRCAPKPGASAGSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQD 308
Query: 1809 PRDCLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIPEDT 1866
+C C C + +F + + G+ + NC+ G CE C Y+
Sbjct: 309 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR-NRRP 367
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS-K 1925
+ C C C + CD + G C+ C + G C+LC PGF G + +
Sbjct: 368 GASIQETCISCECDPD-GAVAGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYANPR 425
Query: 1926 NCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IA 1982
C C C+ G + CD +G C+C P V+G KCD+CAP HW L +G GC PC C
Sbjct: 426 RCHRCDCNILGSREMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHN 485
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCDHCNCNTGYSVGFMCN 2037
S S QC+ GQC C +G G C QC + GC C+C+ + G C+
Sbjct: 486 SLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCD 545
Query: 2038 -ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
A+G+C C PG+ G +CD+C +R C+ C C
Sbjct: 546 KASGRCLCRPGLTGPRCDQC-QRGYCNRYPVCVACHPC 582
Score = 151 bits (367), Expect = 4e-35
Identities = 95/325 (29%), Positives = 134/325 (41%), Gaps = 45/325 (13%)
Query: 398 FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE-----------DGYYSP 446
F + + C + G +C C++N AG +CE C +G +
Sbjct: 251 FCHGHADRCAPKPGASAGSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAH 310
Query: 447 ECKNCECNTVGSVSYVCDKLT--------GDC-TCKSKYSGRTCNQCQAGYYN------- 490
EC+ C+CN + + G C C+ G+ C +CQ Y+
Sbjct: 311 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 370
Query: 491 -YPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPC 548
TC C CD G CD V+GQC+CK G RCD C G+ R+C C
Sbjct: 371 IQETCISCECDPDGAVAGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPRRCHRC 430
Query: 549 NCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYPD---CLSCNCDVSGSIGST 604
+C+ GS C + G+C CL N G +CDQC+P ++K C C CD S+
Sbjct: 431 DCNILGSREMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 490
Query: 605 CDD-NGLCHCKSNFDGAKCDT-----CREQFYNYPA--CEECNCDPRGVTASFAGCGSVP 656
C+ G C C+ F G C C ++ Y A C C+CD RG G G
Sbjct: 491 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT----EGPGCDK 546
Query: 657 AGELCQCKDRVQGRICNDCKPLYWN 681
A C C+ + G C+ C+ Y N
Sbjct: 547 ASGRCLCRPGLTGPRCDQCQRGYCN 571
Score = 143 bits (346), Expect = 1e-32
Identities = 95/304 (31%), Positives = 136/304 (44%), Gaps = 48/304 (15%)
Query: 516 CICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNC---------DPTGSTSTSCS 561
C+C+ GP C++C Y + G++ +C C+C DP ++ +
Sbjct: 278 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 337
Query: 562 ADGKC-NCLTNFGGAQCDQCSPGYYK--------YPDCLSCNCDVSGSI-GSTCDD-NGL 610
G C NC + G C++C Y++ C+SC CD G++ G+ CD G
Sbjct: 338 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVAGAPCDPVTGQ 397
Query: 611 CHCKSNFDGAKCDTCREQF----YNYPA-CEECNCDPRGVTASFAGCGSVPAGELCQCKD 665
C CK + G +CD C+ F Y P C C+C+ G + C +G C C
Sbjct: 398 CVCKEHVQGERCDLCKPGFTGLTYANPRRCHRCDCNILG--SREMPCDE-ESGR-CLCLP 453
Query: 666 RVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQC 725
V G C+ C P +W L GCE C C+ +L+ CN +GQC C++ G C
Sbjct: 454 NVVGPKCDQCAPYHWKLASGQ--GCEPCACDPHNSLSP--QCNQFTGQCPCREGFGGLMC 509
Query: 726 D-----QCLDGFYRLQTNDVF-GCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
QC D Y DV GC CDCD G+ CDK +G+C C + G RCDQ
Sbjct: 510 SAAAIRQCPDRTY----GDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 565
Query: 780 IRAH 783
R +
Sbjct: 566 QRGY 569
Score = 142 bits (344), Expect = 2e-32
Identities = 95/309 (30%), Positives = 126/309 (40%), Gaps = 44/309 (14%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G +CE+CA + P + C C CNGHS+ C +
Sbjct: 278 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 337
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDATVGT--PRDCLICACPMPYPSNNFA-LSCDLS 1833
G+C NC D+T G +CE C Y + G C+ C C P A CD
Sbjct: 338 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD---PDGAVAGAPCDPV 394
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
C C+ G RC+ C G+ G+ C C+C NI CD
Sbjct: 395 TG----QCVCKEHVQGERCDLCKPGFTGLTYANPRR----CHRCDC--NILGSREMPCDE 444
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRP 1951
+G CL C+ N G C+ CAP ++ + C C CD C+ TG C CR
Sbjct: 445 ESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 502
Query: 1952 GVIGEKCDRCA----PDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQC 2006
G G C A PD + GC C+C +E CD +G+C C G+TG +C
Sbjct: 503 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 562
Query: 2007 DQCAAGFWN 2015
DQC G+ N
Sbjct: 563 DQCQRGYCN 571
Score = 120 bits (288), Expect = 1e-25
Identities = 65/196 (33%), Positives = 91/196 (46%), Gaps = 20/196 (10%)
Query: 1340 CLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYG--FPNCRPCH-CPSTAI-- 1393
C CD G+ C+ GQC CK +V G C C+ G+ G + N R CH C +
Sbjct: 378 CECDPDGAVAGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPRRCHRCDCNILGS 437
Query: 1394 ----CDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADS 1448
CD+ +G C+C NV G CD+C PY + +GC+ C C+P + QC +
Sbjct: 438 REMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP--QCNQFT 495
Query: 1449 GKCACRENVRGRVCD-----HCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCKT 1501
G+C CRE G +C C Y C C C+ GT CD+ + +C C+
Sbjct: 496 GQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRP 555
Query: 1502 NVRGQACDTCKEEYFN 1517
+ G CD C+ Y N
Sbjct: 556 GLTGPRCDQCQRGYCN 571
Score = 105 bits (252), Expect = 3e-21
Identities = 64/211 (30%), Positives = 92/211 (43%), Gaps = 20/211 (9%)
Query: 593 CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCD 641
C S GST + +C C+ N G C+ C + N P C+ C+C+
Sbjct: 259 CAPKPGASAGSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN 318
Query: 642 PRGVT-----ASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQC 693
T A FA G C+D +G+ C C+ Y+ + C C
Sbjct: 319 GHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISC 378
Query: 694 NCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS 753
C+ G + C+ +GQCVCK+HV +CD C GF L + C CDC+I GS
Sbjct: 379 ECDPDGAVAG-APCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPRRCHRCDCNILGS 437
Query: 754 IDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
+ CD+ +G+C C V G +CDQ H+
Sbjct: 438 REMPCDEESGRCLCLPNVVGPKCDQCAPYHW 468
Score = 102 bits (245), Expect = 2e-20
Identities = 64/207 (30%), Positives = 90/207 (43%), Gaps = 37/207 (17%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC----------PSTAICDDN- 1397
C C+ N G C C Y P C+ C C P+
Sbjct: 278 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 337
Query: 1398 --GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
G+C C + EG+NC+RC+ + F +Q C C C+P G V C+ +G
Sbjct: 338 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVAGA-PCDPVTG 396
Query: 1450 KCACRENVRGRVCDHCVPGH----YAFPD-CYQCTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
+C C+E+V+G CD C PG YA P C++C CN G+ CD+ + +C C NV
Sbjct: 397 QCVCKEHVQGERCDLCKPGFTGLTYANPRRCHRCDCNILGSREMPCDEESGRCLCLPNVV 456
Query: 1505 GQACDTCKEEYFNLQDDNPDGCTKCFC 1531
G CD C ++ L + GC C C
Sbjct: 457 GPKCDQCAPYHWKLA--SGQGCEPCAC 481
Score = 91.9 bits (218), Expect = 4e-17
Identities = 53/180 (29%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
++ LC+ +T C C+ +GS E+ C+ G+C C PNV+G C
Sbjct: 403 HVQGERCDLCKPGFTGLTYANPRRCHRCDCNILGSREMPCDEESGRCLCLPNVVGPKCDQ 462
Query: 1373 CRTGYYGFPN---CRPCHC-PSTAI---CDD-NGMCICPKNVEGENCD-----RCKPYTF 1419
C ++ + C PC C P ++ C+ G C C + G C +C T+
Sbjct: 463 CAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTY 522
Query: 1420 NFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQC 1478
DV GC C+C+ G G C+ SG+C CR + G CD C G+ +P C C
Sbjct: 523 G-DVATGCRACDCDFRGTEGP--GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 579
Score = 81.0 bits (191), Expect = 7e-14
Identities = 51/165 (30%), Positives = 69/165 (41%), Gaps = 24/165 (14%)
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFN--FDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
STA+ + +C+C N G NC+RC P+ N + G D C G+ C D
Sbjct: 269 STAV-QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFD 327
Query: 1448 -----------SGKCA-CRENVRGRVCDHCV--------PGHYAFPDCYQCTCNRHGTTY 1487
G C CR++ G+ C+ C PG C C C+ G
Sbjct: 328 PAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVA 387
Query: 1488 DV-CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T QC CK +V+G+ CD CK + L NP C +C C
Sbjct: 388 GAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPRRCHRCDC 432
Score = 60.1 bits (139), Expect = 1e-07
Identities = 46/162 (28%), Positives = 63/162 (38%), Gaps = 25/162 (15%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGLG---CTPCNCGIASESTQCDDD-------- 1991
CVC+ G C+RCAP + W G C C+C SE+ D
Sbjct: 278 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 337
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG------CDHCNCNT-GYSVGFMCN-ATGQ 2041
G C C GK C++C ++ + G C C C+ G G C+ TGQ
Sbjct: 338 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVAGAPCDPVTGQ 397
Query: 2042 CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVE 2083
C C V GE+CD C + + C C ++ S E
Sbjct: 398 CVCKEHVQGERCDLCKPGFTGLTYANPRRCHRCDCNILGSRE 439
>Z99289-2|CAI42325.1| 1823|Homo sapiens laminin, alpha 4 protein.
Length = 1823
Score = 263 bits (644), Expect = 1e-68
Identities = 309/1315 (23%), Positives = 525/1315 (39%), Gaps = 134/1315 (10%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 79 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 133
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIAS 1983
C +A+ C G C+C G C+RCAP ++G L G C C+C S
Sbjct: 134 CPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
Query: 1984 EST----QCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMC 2036
+ CD+ GQCR C + TG +C++CA G++ + C CNC G C
Sbjct: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PC 248
Query: 2037 NA-TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
++ TG+C G CP + CD C L ++ L+AL E
Sbjct: 249 DSVTGEC-LEEGFEPPTGMDCPT----------ISCDKCVWDLTDALR-LAALSIEEGKS 296
Query: 2096 FKDKADSFFTTQR-LNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEF 2154
S R +N I+ LL+ K+++ + I E + K+LL E
Sbjct: 297 GVLSVSSGAAAHRHVNEINATIYLLKTKLSEREN-QYALRKIQINNAENTMKSLLSDVE- 354
Query: 2155 AATDSDKQISRAAKLAE----DAERTLAAVRESAREATEVVKHVAD--LATGLELSQQPK 2208
+ + Q SR +L + D + + E A + + ++ + + L G E PK
Sbjct: 355 ELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPK 414
Query: 2209 -VDSALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRP 2267
+ L A+++ ++I + P Q E V E ++ Q + Q + R
Sbjct: 415 EISEKLVLAQKMLEEIRSRQ--PFFTQRELVDEEADEAYELLS---QAESWQRLHNETRT 469
Query: 2268 DLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNSVTKLNTA 2327
F ++ + KL D+ E D A + AE++N R + + + +
Sbjct: 470 --LFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMN---RATAARQRDHEKQQERVR 524
Query: 2328 AMGDLIDAAYDIG-NATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEH 2386
++++ + ++ L H
Sbjct: 525 EQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSH 584
Query: 2387 -LTSEATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXX 2445
L EA HA L++ A+ L + N Q ++
Sbjct: 585 DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFA 644
Query: 2446 XXXXXNVTKLNRILDERVRPARERSSSLLADA----TKAQHAVDQKLLPNLTATEEVLRK 2501
+ +D ++ ++ S +LL A KA+ + D+ + L +
Sbjct: 645 LNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALAR 704
Query: 2502 IRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKD 2561
+R D +Q + N T T V P +
Sbjct: 705 KSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRT---TMEVQQATAPMANNLTN 761
Query: 2562 WAQTLPKLADEGQKMTSN-VESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQ 2620
W+Q L N ++N+ ++ PQ+ TV+ +Q
Sbjct: 762 WSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSAS-----IQ 816
Query: 2621 KLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR--------TK 2672
++++L+ Q R+VA++IQV + FD S ++ ++D++ T +S Y + T+
Sbjct: 817 RIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTE 876
Query: 2673 EKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMV 2732
D FILYLG+ + +YM + I+N V ++G + +D
Sbjct: 877 TADQFILYLGS-------KNAKKEYMGLAIKNDNLVYVYNLGTKD------VEIPLDSKP 923
Query: 2733 ADN--RWYQVI-VDRLGRRVKLSIR-ESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLY 2788
+ ++ ++ ++R+G+ K+ + SL + + K+ + G ++ +LD E + Y
Sbjct: 924 VSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFY 983
Query: 2789 VGGVPSDAKL-QGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQ----RDKLISS 2843
VGGVPS+ KL ++ P F G +E + + + L+NF + + RDKL +
Sbjct: 984 VGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFT 1043
Query: 2844 QSGPQEYRFDGRGYATMAG--RGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
QS Y FDG GYA + R Q + + RT A NGLI L+ G FF L M+
Sbjct: 1044 QSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMR 1103
Query: 2902 DGRVYLQVSLGNTEDLIIVGTT---RAYNDGKWHKLD-ARRFLAKCSLTVDNEVLKAESN 2957
+G +++ G + + + T ND K+H++ K L VD +K+ N
Sbjct: 1104 NGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDN 1163
Query: 2958 SPSADIPSLDTMNFGGNNKGILQ-------VP-DRGFDGCMRQISINGVNLDLSENLESI 3009
IP D + GG ILQ +P D F GCM+ + +L E E++
Sbjct: 1164 E-KMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETL 1221
Query: 3010 GMAYGCQFASLVS----FNGTDSYLRFVDVTS--ENPQLTLKFKTAKPNGLLFVYVSRTQ 3063
G+ YGC SL+S FNG S++ + S + + F+T +PNGLLF Y S +
Sbjct: 1222 GVGYGCPEDSLISRRAYFNG-QSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGS- 1279
Query: 3064 TAIMPDSISLSLVNGKLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVD 3118
D S+SL NG +++ + ++ + YND H + + + + +L+VD
Sbjct: 1280 -----DVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1329
Score = 206 bits (503), Expect = 1e-51
Identities = 94/204 (46%), Positives = 120/204 (58%), Gaps = 11/204 (5%)
Query: 1746 SCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
+ E+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G P+ C C CP+P+ + NFA SC +NG+ + C C Y G CE CA GYYG P
Sbjct: 123 RGAPQFCQPCPCPLPHLA-NFAESC-YRKNGA-VRCICNENYAGPNCERCAPGYYGNP-- 177
Query: 1866 TDLHTGDYCKPCNCSGNINPQ-DPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
L G CK C+CSGN +P CD + G C C+ NT G C CAPG+YGDA +
Sbjct: 178 --LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1925 KNCTACICDEFGMADCDSTTGTCV 1948
KNC C C G CDS TG C+
Sbjct: 236 KNCAVCNC---GGGPCDSVTGECL 256
Score = 146 bits (353), Expect = 2e-33
Identities = 105/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 1470 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 1525
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S YND WH V R G+L +D V E S+
Sbjct: 1526 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1585
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 1586 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 1644
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 1645 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1700
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 1701 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 1757
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 1758 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1816
Query: 3662 VGVCP 3666
+ CP
Sbjct: 1817 INSCP 1821
Score = 105 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 31/204 (15%)
Query: 387 PPDCSSCAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGY 443
PP C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 444 Y------SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQCQAGYYNYP 492
+P+ C+ C C + + + C + G C C Y+G C +C GYY P
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 493 -----TCKPCNCDTSGTEPSI----CDDVSGQC-ICKAGFGGPRCDQCLSGYYMQVLGRE 542
TCK C+C + ++P++ CD+V+GQC C G +C++C GYY
Sbjct: 178 LLIGSTCKKCDC-SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIA 235
Query: 543 RQCVPCNC--DPTGSTSTSCSADG 564
+ C CNC P S + C +G
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEG 259
Score = 99 bits (238), Expect = 1e-19
Identities = 66/200 (33%), Positives = 86/200 (43%), Gaps = 40/200 (20%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 79 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 348 YGKRWDELDVCQPCQCD-PHFS--TGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
+ + CQPC C PH + +C ++G RC C + P+C CA GY+ P
Sbjct: 121 SIRGAPQF--CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Query: 402 ----NCKPCTCNLNGTEG---EHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE--CKNC 451
CK C C+ N E C G C C N G CE C GYY KNC
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
Query: 452 E-CNTVGSVSYVCDKLTGDC 470
CN G CD +TG+C
Sbjct: 239 AVCNCGGG---PCDSVTGEC 255
Score = 90.2 bits (214), Expect = 1e-16
Identities = 63/197 (31%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 435 SCEICEDGYY---SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGYYN 490
+ E C G++ S EC C+CN G+ S C +G C C+ +G C +C GY
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCN--GN-SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 491 YPT------CKPCNCDTS--GTEPSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLG 540
C+PC C C +G +CIC + GP C++C GYY L
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 541 RERQCVPCNC----DPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
C C+C DP G+C NCL N G +C++C+PGYY ++ NC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 596 DVSGSIGSTCDD-NGLC 611
V G CD G C
Sbjct: 239 AVCNCGGGPCDSVTGEC 255
Score = 82.6 bits (195), Expect = 2e-14
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 67 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVPGHYAFP-----DCY 1476
C C C PL + N + C +G +C C EN G C+ C PG+Y P C
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
Query: 1477 QCTCNRH---GTTYDVCDQNTAQC-YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCF 1532
+C C+ + ++ CD+ T QC C N G C+ C Y+ C C C
Sbjct: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
Query: 1533 G 1533
G
Sbjct: 245 G 245
Score = 79.8 bits (188), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 1729 RATSVEECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCNGHSD------QCDVNTG 1779
R C C Y G +CE+CA G+Y P C C C+G+SD CD TG
Sbjct: 148 RKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
Score = 77.4 bits (182), Expect = 9e-13
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 28/174 (16%)
Query: 1738 CPRAYRGLSCEQCAEGH----YRLPSGFCVPCQC-----NGHSDQCDVNTGI--CLNCAD 1786
C R G CE+C +G+ R FC PC C ++ C G C+ C +
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNE 159
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
N G +CE C GY+G+ + C C C N CD G NC
Sbjct: 160 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCD-EVTGQ--CRNCLRN 215
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 216 TTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 257
Score = 76.6 bits (180), Expect = 2e-12
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%)
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPG 583
P ++C +G++ + G +CVPC+C+ G+++ G C +C N G C++C G
Sbjct: 62 PAAEKCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 584 YYK-----YPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCDTCREQFYNY 632
Y P C C C + + +C NG C C N+ G C+ C +Y
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 633 P-----ACEECNCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
P C++C+C F C V G+ C G C C P Y+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEV-TGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 687 PFGCEQCNCNLAGTLNSL-GACNTKSGQCVCKQHVGERQCDQCL 729
C CNC G +S+ G C + + CD+C+
Sbjct: 236 K-NCAVCNCG-GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
Score = 76.2 bits (179), Expect = 2e-12
Identities = 55/180 (30%), Positives = 75/180 (41%), Gaps = 30/180 (16%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY-----GFPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 82 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 140
Query: 1395 D-------DNG--MCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGVVGNQLQ 1443
+ NG CIC +N G NC+RC P + + G C C+C+ +
Sbjct: 141 NFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFE 200
Query: 1444 -CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 255
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 1909 ACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG 1967
A C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 63 AAEKCNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 1968 ---LNTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN---Y 2016
C PC C +A+ + C NG +C C + G C++CA G++
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 2017 TKDGCDHCNCNTGYSVGFM---CN-ATGQC-ECLPGVIGEKCDRC 2056
C C+C+ + C+ TGQC CL G KC+RC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + YND
Sbjct: 1493 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYND 1550
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 1551 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 1610
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 1611 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 1666
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 1667 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 1724
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 1725 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 1782
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 1783 LAPSKPFTGCIRHFVIDG 1800
Score = 68.9 bits (161), Expect = 3e-10
Identities = 59/204 (28%), Positives = 78/204 (38%), Gaps = 39/204 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 82 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 131
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + S R G +C+ C N G NC +C P Y YG
Sbjct: 132 CPCPL--------PHLANFAESC---YRKNGAVRCI-CNENYAGPNCERCAPGY---YGN 176
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFD----YP 401
C+ C C DP+ +C+E +G+C C C CA GY+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLC 425
NC C C G C G C
Sbjct: 237 NCAVCNCG-----GGPCDSVTGEC 255
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY-WN 681
+ C F++ + E CD G + GS G C+ G C C Y +
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLD-GS---GYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHVGERQCDQCLDGFYRLQTND 739
P C+ C C L N +C K+G +C+C ++ C++C G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 740 VFGCTECDCDIGGSIDN----NCDKTTGQC-HCHSRVEGRRCDQPIRAHY 784
C +CDC G S N +CD+ TGQC +C G +C++ +Y
Sbjct: 181 GSTCKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 56.0 bits (129), Expect = 2e-06
Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 26/140 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C N GP C +C G+ I +C+ C+C ++ DP + +
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNL----IFE 200
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D + E G+C NC NT G C +C P YY + C C C G C+
Sbjct: 201 DCD---EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCD 249
Query: 374 EESGRCECRPEFQPPDCSSC 393
+G C F+PP C
Sbjct: 250 SVTGEC-LEEGFEPPTGMDC 268
Score = 55.2 bits (127), Expect = 4e-06
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 17/111 (15%)
Query: 1339 PCLCDFMGSTELECNTFGG--QCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHCPST 1391
PC + + C G +C C N G C C GYYG P C+ C C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN 192
Query: 1392 A-------ICDD-NGMC-ICPKNVEGENCDRCKP-YTFNFDVQRGCDDCNC 1432
+ CD+ G C C +N G C+RC P Y + + + C CNC
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC 243
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 3041 QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV---VSQREQLDTGLNTYN 3097
Q +++ +T +G++F YVS + D ++L L +G+LV V ++ YN
Sbjct: 1494 QFSIRLRTRSSHGMIF-YVSDQEEN---DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYN 1549
Query: 3098 DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAP-PPLHILDGVLFIGGVQPGYVVSG-SLG 3155
D WH + S+ +LV+D P + G +++GGV PG V +
Sbjct: 1550 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQIN 1609
Query: 3156 SKVPFTGCIGDATING-QVLNLLEPFSNNSVTFG--RCGTTITTGG 3198
S F+GC+ + +NG + + + FS G GT +T G
Sbjct: 1610 SIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEG 1655
Score = 46.0 bits (104), Expect = 0.003
Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 1488 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 1539
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + D W+ VI R +L I D + E LP
Sbjct: 1540 ------LKIRSQEKYNDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 1585
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 1586 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 1631
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 1632 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 1688
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 1689 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 1748
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 1749 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1807
Score = 38.7 bits (86), Expect = 0.39
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN---------TGY 2030
G ++ Q + + R A G ++C AGF++ C C+CN +GY
Sbjct: 38 GSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGY 97
Query: 2031 SVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
V N TG+ CE CL G IG+ P+
Sbjct: 98 CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
>U17760-1|AAC51352.1| 1172|Homo sapiens laminin S B3 chain protein.
Length = 1172
Score = 263 bits (644), Expect = 1e-68
Identities = 160/518 (30%), Positives = 242/518 (46%), Gaps = 55/518 (10%)
Query: 58 WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQ 117
WWQS N V+L +DL + F + V ++ P P ++E+S+D+GKT++ +Q
Sbjct: 94 WWQSQN-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQ 147
Query: 118 YFSDSPQDCERYFGK-ESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
Y + DC F + +P + D S L G++ ++L+ D S
Sbjct: 148 YLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLM-DLVSGIPAT 203
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S +QE TN+R+ R L + P+ +Y++ + + G C C+GH
Sbjct: 204 QSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGH 255
Query: 237 ADTCEP-----ADPAGNLNIL-VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
AD C P A P+ + + VC CQHNT GP C +C + + WR ++ D C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR 315
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C+ H+ C +DP + G Y GG C NC+ +TEG NC +C+ Y+R
Sbjct: 316 CDCNGHSETCHFDPAVFAAS-----QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 351 RWDELDVCQPCQCDPHFST--GNCEEESGRCECRPEFQPPDCSSCAYGY--FDYPN---C 403
+ C C+CDP + C+ +G+C C+ Q C C G+ Y N C
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 404 KPCTCNLNGTEGE-HCTPTDGLCPCKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
C CN+ G+ + C G C C N G C+ C ++ C+ C C+ S
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCN-----QC-QAGYYNYPT-CKPCNCDTSGTEPSICDD 511
+S C++ TG C C+ + G C+ QC Y + T C+ C+CD GTE CD
Sbjct: 489 LSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
SG+C+C+ G GPRCDQC GY R CV C+
Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGY----CNRYPVCVACH 582
Score = 169 bits (412), Expect = 1e-40
Identities = 107/341 (31%), Positives = 152/341 (44%), Gaps = 37/341 (10%)
Query: 1765 CQCNGHSDQCDVNTG-------------ICLNCADNTIGDHCEFCMSGYHG----DATVG 1807
C C+GH+D+C G +C+ C NT G +CE C Y+ A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1808 TPRDCLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIPED 1865
+C C C + +F + + G+ + NC+ G CE C Y+
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR-NRR 367
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
+ C C C + PG+ CD + G C+ C + G C+LC PGF G +
Sbjct: 368 PGASIQETCISCECDPD--GAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYAN 424
Query: 1925 -KNCTACICDEFGMA---DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG 1980
+ C C C+ G CD +G C+C P V+G KCD+CAP HW L +G GC PC C
Sbjct: 425 PQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1981 -IASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCDHCNCNTGYSVGF 2034
S S QC+ GQC C +G G C QC + GC C+C+ + G
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 2035 MCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
C+ A+G+C C PG+ G +CD+C +R C+ C C
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQC-QRGYCNRYPVCVACHPC 584
Score = 160 bits (389), Expect = 8e-38
Identities = 99/307 (32%), Positives = 138/307 (44%), Gaps = 49/307 (15%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTPT------- 421
C C+ P+C CA Y + P C+ C CN +E H P
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQG 337
Query: 422 --DGLCP-CKYNYAGKSCEICEDGYY---------SPECKNCECNTVGSVSYV-CDKLTG 468
G+C C+ + GK+CE C+ Y+ C +CEC+ G+V CD +TG
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 469 DCTCKSKYSGRTCNQCQAG-----YYNYPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGF 522
C CK G C+ C+ G Y N C C+C+ G+ + CD+ SG+C+C
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCD--- 578
GP+CDQC ++ G+ C PC CDP S S C+ G+C C FGG C
Sbjct: 458 VGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Query: 579 --QCSPGYYK--YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYN-Y 632
QC Y C +C+CD G+ G CD +G C C+ G +CD C+ + N Y
Sbjct: 516 IRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRY 575
Query: 633 PACEECN 639
P C C+
Sbjct: 576 PVCVACH 582
Score = 147 bits (357), Expect = 6e-34
Identities = 98/314 (31%), Positives = 138/314 (43%), Gaps = 47/314 (14%)
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNC---------D 551
PS V C+C+ GP C++C Y + G++ +C C+C D
Sbjct: 269 PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFD 328
Query: 552 PTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYK--------YPDCLSCNCDVSGSI- 601
P ++ + G C NC + G C++C Y++ C+SC CD G++
Sbjct: 329 PAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 602 GSTCDD-NGLCHCKSNFDGAKCDTCREQF----YNYP-ACEECNCDPRGVTASFAGCGSV 655
G+ CD G C CK + G +CD C+ F Y P C C+C+ G C
Sbjct: 389 GAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMP-CDE- 446
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
+G C C V G C+ C P +W L GCE C C+ +L+ CN +GQC
Sbjct: 447 ESGR-CLCLPNVVGPKCDQCAPYHWKLASGQ--GCEPCACDPHNSLSP--QCNQFTGQCP 501
Query: 716 CKQHVGERQCD-----QCLDGFYRLQTNDVF-GCTECDCDIGGSIDNNCDKTTGQCHCHS 769
C++ G C QC D Y DV GC CDCD G+ CDK +G+C C
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTY----GDVATGCRACDCDFRGTEGPGCDKASGRCLCRP 557
Query: 770 RVEGRRCDQPIRAH 783
+ G RCDQ R +
Sbjct: 558 GLTGPRCDQCQRGY 571
Score = 145 bits (352), Expect = 2e-33
Identities = 92/300 (30%), Positives = 128/300 (42%), Gaps = 46/300 (15%)
Query: 424 LCPCKYNYAGKSCEICE-----------DGYYSPECKNCECNTVGSVSYVCDKLT----- 467
+C C++N AG +CE C +G + EC+ C+CN + +
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 468 ---GDC-TCKSKYSGRTCNQCQAGYYN--------YPTCKPCNCDTSGTEPSI-CDDVSG 514
G C C+ G+ C +CQ Y+ TC C CD G P CD V+G
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNF 572
QC+CK G RCD C G+ + C C+C+ GS C + G+C CL N
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 573 GGAQCDQCSPGYYKYPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT---- 624
G +CDQC+P ++K C C CD S+ C+ G C C+ F G C
Sbjct: 458 VGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIR 517
Query: 625 -CREQFYNYPA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C ++ Y A C C+CD RG GC A C C+ + G C+ C+ Y N
Sbjct: 518 QCPDRTYGDVATGCRACDCDFRGTEGP--GCDK--ASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 139 bits (336), Expect = 2e-31
Identities = 92/309 (29%), Positives = 126/309 (40%), Gaps = 43/309 (13%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G +CE+CA + P + C C CNGHS+ C +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDATVGT--PRDCLICACPMPYPSNNF-ALSCDLS 1833
G+C NC D+T G +CE C Y + G C+ C C P CD
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD---PDGAVPGAPCDPV 395
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
C C+ G RC+ C G+ G+ C C+C+ + + CD
Sbjct: 396 TG----QCVCKEHVQGERCDLCKPGFTGL----TYANPQGCHRCDCN-ILGSRRDMPCDE 446
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRP 1951
+G CL C+ N G C+ CAP ++ + C C CD C+ TG C CR
Sbjct: 447 ESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 1952 GVIGEKCDRCA----PDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQC 2006
G G C A PD + GC C+C +E CD +G+C C G+TG +C
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 2007 DQCAAGFWN 2015
DQC G+ N
Sbjct: 565 DQCQRGYCN 573
Score = 117 bits (282), Expect = 7e-25
Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 1340 CLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-CPSTAI-- 1393
C CD G+ C+ GQC CK +V G C C+ G+ G P CH C +
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1394 -----CDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
CD+ +G C+C NV G CD+C PY + +GC+ C C+P + QC
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP--QCNQF 496
Query: 1448 SGKCACRENVRGRVCD-----HCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCK 1500
+G+C CRE G +C C Y C C C+ GT CD+ + +C C+
Sbjct: 497 TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
Query: 1501 TNVRGQACDTCKEEYFN 1517
+ G CD C+ Y N
Sbjct: 557 PGLTGPRCDQCQRGYCN 573
Score = 103 bits (248), Expect = 9e-21
Identities = 61/194 (31%), Positives = 87/194 (44%), Gaps = 20/194 (10%)
Query: 610 LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVT-----ASFAGCGS 654
+C C+ N G C+ C + N P C+ C+C+ T A FA
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLGACNTKS 711
G C+D +G+ C C+ Y+ + C C C+ G + C+ +
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPG-APCDPVT 396
Query: 712 GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS-IDNNCDKTTGQCHCHSR 770
GQCVCK+HV +CD C GF L + GC CDC+I GS D CD+ +G+C C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 771 VEGRRCDQPIRAHY 784
V G +CDQ H+
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 103 bits (246), Expect = 2e-20
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 38/208 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC----------PSTAICDDN- 1397
C C+ N G C C Y P C+ C C P+
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1398 --GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
G+C C + EG+NC+RC+ + F +Q C C C+P G V C+ +G
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-PCDPVTG 397
Query: 1450 KCACRENVRGRVCDHCVPGH----YAFPD-CYQCTCNRHGTTYDV-CDQNTAQCYCKTNV 1503
+C C+E+V+G CD C PG YA P C++C CN G+ D+ CD+ + +C C NV
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 1504 RGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
G CD C ++ L + GC C C
Sbjct: 458 VGPKCDQCAPYHWKLA--SGQGCEPCAC 483
Score = 89.8 bits (213), Expect = 2e-16
Identities = 53/181 (29%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCS 1371
++ LC+ +T G C C+ +GS ++ C+ G+C C PNV+G C
Sbjct: 404 HVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCD 463
Query: 1372 ACRTGYYGFPN---CRPCHC-PSTAI---CDD-NGMCICPKNVEGENCD-----RCKPYT 1418
C ++ + C PC C P ++ C+ G C C + G C +C T
Sbjct: 464 QCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRT 523
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQ 1477
+ DV GC C+C+ G G C+ SG+C CR + G CD C G+ +P C
Sbjct: 524 YG-DVATGCRACDCDFRGTEGP--GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 1478 C 1478
C
Sbjct: 581 C 581
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/166 (31%), Positives = 71/166 (42%), Gaps = 24/166 (14%)
Query: 1389 PSTAICDDNGMCICPKNVEGENCDRCKPYTFN--FDVQRGCDDCNCNPLGVVGNQLQCEA 1446
PSTA+ + +C+C N G NC+RC P+ N + G D C G+ C
Sbjct: 269 PSTAV-QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF 327
Query: 1447 D-----------SGKCA-CRENVRGRVCDHCV--------PGHYAFPDCYQCTCNRHGTT 1486
D G C CR++ G+ C+ C PG C C C+ G
Sbjct: 328 DPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV 387
Query: 1487 YDV-CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T QC CK +V+G+ CD CK + L NP GC +C C
Sbjct: 388 PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 66.1 bits (154), Expect = 2e-09
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 13/108 (12%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-----CRTGYYG--FPNCRPCHC 1388
G PC CD S +CN F GQCPC+ G CSA C YG CR C C
Sbjct: 477 GCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDC 536
Query: 1389 PSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
CD +G C+C + G CD+C + Y + V C C
Sbjct: 537 DFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 65.3 bits (152), Expect = 4e-09
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 17/154 (11%)
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY----WNLQE-YNPFGCEQCN 694
C P+ AS +V ++C C+ G C C P Y W E + C++C+
Sbjct: 259 CAPKP-GASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 695 CN-LAGTLNSLGACNTKS-----GQC-VCKQHVGERQCDQCLDGFYRLQTNDVF---GCT 744
CN + T + A S G C C+ H + C++C ++R + C
Sbjct: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 745 ECDCDIGGSIDN-NCDKTTGQCHCHSRVEGRRCD 777
C+CD G++ CD TGQC C V+G RCD
Sbjct: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Score = 53.2 bits (122), Expect = 2e-05
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYG-FPNCRPCH 1387
+G R C CDF G+ C+ G+C C+P + G C C+ GY +P C CH
Sbjct: 529 TGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
>BC075838-1|AAH75838.1| 1172|Homo sapiens laminin, beta 3 protein.
Length = 1172
Score = 263 bits (644), Expect = 1e-68
Identities = 160/518 (30%), Positives = 242/518 (46%), Gaps = 55/518 (10%)
Query: 58 WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQ 117
WWQS N V+L +DL + F + V ++ P P ++E+S+D+GKT++ +Q
Sbjct: 94 WWQSQN-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQ 147
Query: 118 YFSDSPQDCERYFGK-ESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
Y + DC F + +P + D S L G++ ++L+ D S
Sbjct: 148 YLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLM-DLVSGIPAT 203
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S +QE TN+R+ R L + P+ +Y++ + + G C C+GH
Sbjct: 204 QSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGH 255
Query: 237 ADTCEP-----ADPAGNLNIL-VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
AD C P A P+ + + VC CQHNT GP C +C + + WR ++ D C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR 315
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C+ H+ C +DP + G Y GG C NC+ +TEG NC +C+ Y+R
Sbjct: 316 CDCNGHSETCHFDPAVFAAS-----QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 351 RWDELDVCQPCQCDPHFST--GNCEEESGRCECRPEFQPPDCSSCAYGY--FDYPN---C 403
+ C C+CDP + C+ +G+C C+ Q C C G+ Y N C
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 404 KPCTCNLNGTEGE-HCTPTDGLCPCKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
C CN+ G+ + C G C C N G C+ C ++ C+ C C+ S
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCN-----QC-QAGYYNYPT-CKPCNCDTSGTEPSICDD 511
+S C++ TG C C+ + G C+ QC Y + T C+ C+CD GTE CD
Sbjct: 489 LSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
SG+C+C+ G GPRCDQC GY R CV C+
Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGY----CNRYPVCVACH 582
Score = 169 bits (412), Expect = 1e-40
Identities = 107/341 (31%), Positives = 152/341 (44%), Gaps = 37/341 (10%)
Query: 1765 CQCNGHSDQCDVNTG-------------ICLNCADNTIGDHCEFCMSGYHG----DATVG 1807
C C+GH+D+C G +C+ C NT G +CE C Y+ A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1808 TPRDCLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIPED 1865
+C C C + +F + + G+ + NC+ G CE C Y+
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR-NRR 367
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
+ C C C + PG+ CD + G C+ C + G C+LC PGF G +
Sbjct: 368 PGASIQETCISCECDPD--GAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYAN 424
Query: 1925 -KNCTACICDEFGMA---DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG 1980
+ C C C+ G CD +G C+C P V+G KCD+CAP HW L +G GC PC C
Sbjct: 425 PQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1981 -IASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCDHCNCNTGYSVGF 2034
S S QC+ GQC C +G G C QC + GC C+C+ + G
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 2035 MCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
C+ A+G+C C PG+ G +CD+C +R C+ C C
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQC-QRGYCNRYPVCVACHPC 584
Score = 160 bits (389), Expect = 8e-38
Identities = 99/307 (32%), Positives = 138/307 (44%), Gaps = 49/307 (15%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTPT------- 421
C C+ P+C CA Y + P C+ C CN +E H P
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQG 337
Query: 422 --DGLCP-CKYNYAGKSCEICEDGYY---------SPECKNCECNTVGSVSYV-CDKLTG 468
G+C C+ + GK+CE C+ Y+ C +CEC+ G+V CD +TG
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 469 DCTCKSKYSGRTCNQCQAG-----YYNYPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGF 522
C CK G C+ C+ G Y N C C+C+ G+ + CD+ SG+C+C
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCD--- 578
GP+CDQC ++ G+ C PC CDP S S C+ G+C C FGG C
Sbjct: 458 VGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Query: 579 --QCSPGYYK--YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYN-Y 632
QC Y C +C+CD G+ G CD +G C C+ G +CD C+ + N Y
Sbjct: 516 IRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRY 575
Query: 633 PACEECN 639
P C C+
Sbjct: 576 PVCVACH 582
Score = 147 bits (357), Expect = 6e-34
Identities = 98/314 (31%), Positives = 138/314 (43%), Gaps = 47/314 (14%)
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNC---------D 551
PS V C+C+ GP C++C Y + G++ +C C+C D
Sbjct: 269 PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFD 328
Query: 552 PTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYK--------YPDCLSCNCDVSGSI- 601
P ++ + G C NC + G C++C Y++ C+SC CD G++
Sbjct: 329 PAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 602 GSTCDD-NGLCHCKSNFDGAKCDTCREQF----YNYP-ACEECNCDPRGVTASFAGCGSV 655
G+ CD G C CK + G +CD C+ F Y P C C+C+ G C
Sbjct: 389 GAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMP-CDE- 446
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
+G C C V G C+ C P +W L GCE C C+ +L+ CN +GQC
Sbjct: 447 ESGR-CLCLPNVVGPKCDQCAPYHWKLASGQ--GCEPCACDPHNSLSP--QCNQFTGQCP 501
Query: 716 CKQHVGERQCD-----QCLDGFYRLQTNDVF-GCTECDCDIGGSIDNNCDKTTGQCHCHS 769
C++ G C QC D Y DV GC CDCD G+ CDK +G+C C
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTY----GDVATGCRACDCDFRGTEGPGCDKASGRCLCRP 557
Query: 770 RVEGRRCDQPIRAH 783
+ G RCDQ R +
Sbjct: 558 GLTGPRCDQCQRGY 571
Score = 145 bits (352), Expect = 2e-33
Identities = 92/300 (30%), Positives = 128/300 (42%), Gaps = 46/300 (15%)
Query: 424 LCPCKYNYAGKSCEICE-----------DGYYSPECKNCECNTVGSVSYVCDKLT----- 467
+C C++N AG +CE C +G + EC+ C+CN + +
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 468 ---GDC-TCKSKYSGRTCNQCQAGYYN--------YPTCKPCNCDTSGTEPSI-CDDVSG 514
G C C+ G+ C +CQ Y+ TC C CD G P CD V+G
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNF 572
QC+CK G RCD C G+ + C C+C+ GS C + G+C CL N
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 573 GGAQCDQCSPGYYKYPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT---- 624
G +CDQC+P ++K C C CD S+ C+ G C C+ F G C
Sbjct: 458 VGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIR 517
Query: 625 -CREQFYNYPA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C ++ Y A C C+CD RG GC A C C+ + G C+ C+ Y N
Sbjct: 518 QCPDRTYGDVATGCRACDCDFRGTEGP--GCDK--ASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 139 bits (336), Expect = 2e-31
Identities = 92/309 (29%), Positives = 126/309 (40%), Gaps = 43/309 (13%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G +CE+CA + P + C C CNGHS+ C +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDATVGT--PRDCLICACPMPYPSNNF-ALSCDLS 1833
G+C NC D+T G +CE C Y + G C+ C C P CD
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD---PDGAVPGAPCDPV 395
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
C C+ G RC+ C G+ G+ C C+C+ + + CD
Sbjct: 396 TG----QCVCKEHVQGERCDLCKPGFTGL----TYANPQGCHRCDCN-ILGSRRDMPCDE 446
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRP 1951
+G CL C+ N G C+ CAP ++ + C C CD C+ TG C CR
Sbjct: 447 ESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 1952 GVIGEKCDRCA----PDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQC 2006
G G C A PD + GC C+C +E CD +G+C C G+TG +C
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 2007 DQCAAGFWN 2015
DQC G+ N
Sbjct: 565 DQCQRGYCN 573
Score = 117 bits (282), Expect = 7e-25
Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 1340 CLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-CPSTAI-- 1393
C CD G+ C+ GQC CK +V G C C+ G+ G P CH C +
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1394 -----CDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
CD+ +G C+C NV G CD+C PY + +GC+ C C+P + QC
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP--QCNQF 496
Query: 1448 SGKCACRENVRGRVCD-----HCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCK 1500
+G+C CRE G +C C Y C C C+ GT CD+ + +C C+
Sbjct: 497 TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
Query: 1501 TNVRGQACDTCKEEYFN 1517
+ G CD C+ Y N
Sbjct: 557 PGLTGPRCDQCQRGYCN 573
Score = 103 bits (248), Expect = 9e-21
Identities = 61/194 (31%), Positives = 87/194 (44%), Gaps = 20/194 (10%)
Query: 610 LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVT-----ASFAGCGS 654
+C C+ N G C+ C + N P C+ C+C+ T A FA
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLGACNTKS 711
G C+D +G+ C C+ Y+ + C C C+ G + C+ +
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPG-APCDPVT 396
Query: 712 GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS-IDNNCDKTTGQCHCHSR 770
GQCVCK+HV +CD C GF L + GC CDC+I GS D CD+ +G+C C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 771 VEGRRCDQPIRAHY 784
V G +CDQ H+
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 103 bits (246), Expect = 2e-20
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 38/208 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC----------PSTAICDDN- 1397
C C+ N G C C Y P C+ C C P+
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1398 --GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
G+C C + EG+NC+RC+ + F +Q C C C+P G V C+ +G
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-PCDPVTG 397
Query: 1450 KCACRENVRGRVCDHCVPGH----YAFPD-CYQCTCNRHGTTYDV-CDQNTAQCYCKTNV 1503
+C C+E+V+G CD C PG YA P C++C CN G+ D+ CD+ + +C C NV
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 1504 RGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
G CD C ++ L + GC C C
Sbjct: 458 VGPKCDQCAPYHWKLA--SGQGCEPCAC 483
Score = 89.8 bits (213), Expect = 2e-16
Identities = 53/181 (29%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCS 1371
++ LC+ +T G C C+ +GS ++ C+ G+C C PNV+G C
Sbjct: 404 HVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCD 463
Query: 1372 ACRTGYYGFPN---CRPCHC-PSTAI---CDD-NGMCICPKNVEGENCD-----RCKPYT 1418
C ++ + C PC C P ++ C+ G C C + G C +C T
Sbjct: 464 QCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRT 523
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQ 1477
+ DV GC C+C+ G G C+ SG+C CR + G CD C G+ +P C
Sbjct: 524 YG-DVATGCRACDCDFRGTEGP--GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 1478 C 1478
C
Sbjct: 581 C 581
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/166 (31%), Positives = 71/166 (42%), Gaps = 24/166 (14%)
Query: 1389 PSTAICDDNGMCICPKNVEGENCDRCKPYTFN--FDVQRGCDDCNCNPLGVVGNQLQCEA 1446
PSTA+ + +C+C N G NC+RC P+ N + G D C G+ C
Sbjct: 269 PSTAV-QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF 327
Query: 1447 D-----------SGKCA-CRENVRGRVCDHCV--------PGHYAFPDCYQCTCNRHGTT 1486
D G C CR++ G+ C+ C PG C C C+ G
Sbjct: 328 DPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV 387
Query: 1487 YDV-CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T QC CK +V+G+ CD CK + L NP GC +C C
Sbjct: 388 PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 66.1 bits (154), Expect = 2e-09
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 13/108 (12%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-----CRTGYYG--FPNCRPCHC 1388
G PC CD S +CN F GQCPC+ G CSA C YG CR C C
Sbjct: 477 GCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDC 536
Query: 1389 PSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
CD +G C+C + G CD+C + Y + V C C
Sbjct: 537 DFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 65.3 bits (152), Expect = 4e-09
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 17/154 (11%)
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY----WNLQE-YNPFGCEQCN 694
C P+ AS +V ++C C+ G C C P Y W E + C++C+
Sbjct: 259 CAPKP-GASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 695 CN-LAGTLNSLGACNTKS-----GQC-VCKQHVGERQCDQCLDGFYRLQTNDVF---GCT 744
CN + T + A S G C C+ H + C++C ++R + C
Sbjct: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 745 ECDCDIGGSIDN-NCDKTTGQCHCHSRVEGRRCD 777
C+CD G++ CD TGQC C V+G RCD
Sbjct: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Score = 53.2 bits (122), Expect = 2e-05
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYG-FPNCRPCH 1387
+G R C CDF G+ C+ G+C C+P + G C C+ GY +P C CH
Sbjct: 529 TGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
>AY035783-1|AAK61364.1| 1172|Homo sapiens laminin 5 beta 3 subunit
protein.
Length = 1172
Score = 263 bits (644), Expect = 1e-68
Identities = 160/518 (30%), Positives = 242/518 (46%), Gaps = 55/518 (10%)
Query: 58 WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQ 117
WWQS N V+L +DL + F + V ++ P P ++E+S+D+GKT++ +Q
Sbjct: 94 WWQSQN-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQ 147
Query: 118 YFSDSPQDCERYFGK-ESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
Y + DC F + +P + D S L G++ ++L+ D S
Sbjct: 148 YLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLM-DLVSGIPAT 203
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S +QE TN+R+ R L + P+ +Y++ + + G C C+GH
Sbjct: 204 QSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGH 255
Query: 237 ADTCEP-----ADPAGNLNIL-VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
AD C P A P+ + + VC CQHNT GP C +C + + WR ++ D C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR 315
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C+ H+ C +DP + G Y GG C NC+ +TEG NC +C+ Y+R
Sbjct: 316 CDCNGHSETCHFDPAVFAAS-----QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 351 RWDELDVCQPCQCDPHFST--GNCEEESGRCECRPEFQPPDCSSCAYGY--FDYPN---C 403
+ C C+CDP + C+ +G+C C+ Q C C G+ Y N C
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 404 KPCTCNLNGTEGE-HCTPTDGLCPCKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
C CN+ G+ + C G C C N G C+ C ++ C+ C C+ S
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCN-----QC-QAGYYNYPT-CKPCNCDTSGTEPSICDD 511
+S C++ TG C C+ + G C+ QC Y + T C+ C+CD GTE CD
Sbjct: 489 LSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
SG+C+C+ G GPRCDQC GY R CV C+
Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGY----CNRYPVCVACH 582
Score = 169 bits (412), Expect = 1e-40
Identities = 107/341 (31%), Positives = 152/341 (44%), Gaps = 37/341 (10%)
Query: 1765 CQCNGHSDQCDVNTG-------------ICLNCADNTIGDHCEFCMSGYHG----DATVG 1807
C C+GH+D+C G +C+ C NT G +CE C Y+ A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1808 TPRDCLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIPED 1865
+C C C + +F + + G+ + NC+ G CE C Y+
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR-NRR 367
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
+ C C C + PG+ CD + G C+ C + G C+LC PGF G +
Sbjct: 368 PGASIQETCISCECDPD--GAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYAN 424
Query: 1925 -KNCTACICDEFGMA---DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG 1980
+ C C C+ G CD +G C+C P V+G KCD+CAP HW L +G GC PC C
Sbjct: 425 PQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1981 -IASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCDHCNCNTGYSVGF 2034
S S QC+ GQC C +G G C QC + GC C+C+ + G
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 2035 MCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
C+ A+G+C C PG+ G +CD+C +R C+ C C
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQC-QRGYCNRYPVCVACHPC 584
Score = 160 bits (389), Expect = 8e-38
Identities = 99/307 (32%), Positives = 138/307 (44%), Gaps = 49/307 (15%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTPT------- 421
C C+ P+C CA Y + P C+ C CN +E H P
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQG 337
Query: 422 --DGLCP-CKYNYAGKSCEICEDGYY---------SPECKNCECNTVGSVSYV-CDKLTG 468
G+C C+ + GK+CE C+ Y+ C +CEC+ G+V CD +TG
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 469 DCTCKSKYSGRTCNQCQAG-----YYNYPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGF 522
C CK G C+ C+ G Y N C C+C+ G+ + CD+ SG+C+C
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCD--- 578
GP+CDQC ++ G+ C PC CDP S S C+ G+C C FGG C
Sbjct: 458 VGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Query: 579 --QCSPGYYK--YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYN-Y 632
QC Y C +C+CD G+ G CD +G C C+ G +CD C+ + N Y
Sbjct: 516 IRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRY 575
Query: 633 PACEECN 639
P C C+
Sbjct: 576 PVCVACH 582
Score = 147 bits (357), Expect = 6e-34
Identities = 98/314 (31%), Positives = 138/314 (43%), Gaps = 47/314 (14%)
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNC---------D 551
PS V C+C+ GP C++C Y + G++ +C C+C D
Sbjct: 269 PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFD 328
Query: 552 PTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYK--------YPDCLSCNCDVSGSI- 601
P ++ + G C NC + G C++C Y++ C+SC CD G++
Sbjct: 329 PAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 602 GSTCDD-NGLCHCKSNFDGAKCDTCREQF----YNYP-ACEECNCDPRGVTASFAGCGSV 655
G+ CD G C CK + G +CD C+ F Y P C C+C+ G C
Sbjct: 389 GAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMP-CDE- 446
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
+G C C V G C+ C P +W L GCE C C+ +L+ CN +GQC
Sbjct: 447 ESGR-CLCLPNVVGPKCDQCAPYHWKLASGQ--GCEPCACDPHNSLSP--QCNQFTGQCP 501
Query: 716 CKQHVGERQCD-----QCLDGFYRLQTNDVF-GCTECDCDIGGSIDNNCDKTTGQCHCHS 769
C++ G C QC D Y DV GC CDCD G+ CDK +G+C C
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTY----GDVATGCRACDCDFRGTEGPGCDKASGRCLCRP 557
Query: 770 RVEGRRCDQPIRAH 783
+ G RCDQ R +
Sbjct: 558 GLTGPRCDQCQRGY 571
Score = 145 bits (352), Expect = 2e-33
Identities = 92/300 (30%), Positives = 128/300 (42%), Gaps = 46/300 (15%)
Query: 424 LCPCKYNYAGKSCEICE-----------DGYYSPECKNCECNTVGSVSYVCDKLT----- 467
+C C++N AG +CE C +G + EC+ C+CN + +
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 468 ---GDC-TCKSKYSGRTCNQCQAGYYN--------YPTCKPCNCDTSGTEPSI-CDDVSG 514
G C C+ G+ C +CQ Y+ TC C CD G P CD V+G
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNF 572
QC+CK G RCD C G+ + C C+C+ GS C + G+C CL N
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 573 GGAQCDQCSPGYYKYPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT---- 624
G +CDQC+P ++K C C CD S+ C+ G C C+ F G C
Sbjct: 458 VGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIR 517
Query: 625 -CREQFYNYPA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C ++ Y A C C+CD RG GC A C C+ + G C+ C+ Y N
Sbjct: 518 QCPDRTYGDVATGCRACDCDFRGTEGP--GCDK--ASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 139 bits (336), Expect = 2e-31
Identities = 92/309 (29%), Positives = 126/309 (40%), Gaps = 43/309 (13%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G +CE+CA + P + C C CNGHS+ C +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDATVGT--PRDCLICACPMPYPSNNF-ALSCDLS 1833
G+C NC D+T G +CE C Y + G C+ C C P CD
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD---PDGAVPGAPCDPV 395
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
C C+ G RC+ C G+ G+ C C+C+ + + CD
Sbjct: 396 TG----QCVCKEHVQGERCDLCKPGFTGL----TYANPQGCHRCDCN-ILGSRRDMPCDE 446
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRP 1951
+G CL C+ N G C+ CAP ++ + C C CD C+ TG C CR
Sbjct: 447 ESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 1952 GVIGEKCDRCA----PDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQC 2006
G G C A PD + GC C+C +E CD +G+C C G+TG +C
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 2007 DQCAAGFWN 2015
DQC G+ N
Sbjct: 565 DQCQRGYCN 573
Score = 117 bits (282), Expect = 7e-25
Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 1340 CLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-CPSTAI-- 1393
C CD G+ C+ GQC CK +V G C C+ G+ G P CH C +
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1394 -----CDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
CD+ +G C+C NV G CD+C PY + +GC+ C C+P + QC
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP--QCNQF 496
Query: 1448 SGKCACRENVRGRVCD-----HCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCK 1500
+G+C CRE G +C C Y C C C+ GT CD+ + +C C+
Sbjct: 497 TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
Query: 1501 TNVRGQACDTCKEEYFN 1517
+ G CD C+ Y N
Sbjct: 557 PGLTGPRCDQCQRGYCN 573
Score = 103 bits (248), Expect = 9e-21
Identities = 61/194 (31%), Positives = 87/194 (44%), Gaps = 20/194 (10%)
Query: 610 LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVT-----ASFAGCGS 654
+C C+ N G C+ C + N P C+ C+C+ T A FA
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLGACNTKS 711
G C+D +G+ C C+ Y+ + C C C+ G + C+ +
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPG-APCDPVT 396
Query: 712 GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS-IDNNCDKTTGQCHCHSR 770
GQCVCK+HV +CD C GF L + GC CDC+I GS D CD+ +G+C C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 771 VEGRRCDQPIRAHY 784
V G +CDQ H+
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 103 bits (246), Expect = 2e-20
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 38/208 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC----------PSTAICDDN- 1397
C C+ N G C C Y P C+ C C P+
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1398 --GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
G+C C + EG+NC+RC+ + F +Q C C C+P G V C+ +G
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-PCDPVTG 397
Query: 1450 KCACRENVRGRVCDHCVPGH----YAFPD-CYQCTCNRHGTTYDV-CDQNTAQCYCKTNV 1503
+C C+E+V+G CD C PG YA P C++C CN G+ D+ CD+ + +C C NV
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 1504 RGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
G CD C ++ L + GC C C
Sbjct: 458 VGPKCDQCAPYHWKLA--SGQGCEPCAC 483
Score = 89.8 bits (213), Expect = 2e-16
Identities = 53/181 (29%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCS 1371
++ LC+ +T G C C+ +GS ++ C+ G+C C PNV+G C
Sbjct: 404 HVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCD 463
Query: 1372 ACRTGYYGFPN---CRPCHC-PSTAI---CDD-NGMCICPKNVEGENCD-----RCKPYT 1418
C ++ + C PC C P ++ C+ G C C + G C +C T
Sbjct: 464 QCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRT 523
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQ 1477
+ DV GC C+C+ G G C+ SG+C CR + G CD C G+ +P C
Sbjct: 524 YG-DVATGCRACDCDFRGTEGP--GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 1478 C 1478
C
Sbjct: 581 C 581
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/166 (31%), Positives = 71/166 (42%), Gaps = 24/166 (14%)
Query: 1389 PSTAICDDNGMCICPKNVEGENCDRCKPYTFN--FDVQRGCDDCNCNPLGVVGNQLQCEA 1446
PSTA+ + +C+C N G NC+RC P+ N + G D C G+ C
Sbjct: 269 PSTAV-QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF 327
Query: 1447 D-----------SGKCA-CRENVRGRVCDHCV--------PGHYAFPDCYQCTCNRHGTT 1486
D G C CR++ G+ C+ C PG C C C+ G
Sbjct: 328 DPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV 387
Query: 1487 YDV-CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T QC CK +V+G+ CD CK + L NP GC +C C
Sbjct: 388 PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 66.1 bits (154), Expect = 2e-09
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 13/108 (12%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-----CRTGYYG--FPNCRPCHC 1388
G PC CD S +CN F GQCPC+ G CSA C YG CR C C
Sbjct: 477 GCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDC 536
Query: 1389 PSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
CD +G C+C + G CD+C + Y + V C C
Sbjct: 537 DFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 65.3 bits (152), Expect = 4e-09
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 17/154 (11%)
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY----WNLQE-YNPFGCEQCN 694
C P+ AS +V ++C C+ G C C P Y W E + C++C+
Sbjct: 259 CAPKP-GASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 695 CN-LAGTLNSLGACNTKS-----GQC-VCKQHVGERQCDQCLDGFYRLQTNDVF---GCT 744
CN + T + A S G C C+ H + C++C ++R + C
Sbjct: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 745 ECDCDIGGSIDN-NCDKTTGQCHCHSRVEGRRCD 777
C+CD G++ CD TGQC C V+G RCD
Sbjct: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Score = 53.2 bits (122), Expect = 2e-05
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYG-FPNCRPCH 1387
+G R C CDF G+ C+ G+C C+P + G C C+ GY +P C CH
Sbjct: 529 TGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
>AL590106-3|CAI12950.1| 1823|Homo sapiens laminin, alpha 4 protein.
Length = 1823
Score = 263 bits (644), Expect = 1e-68
Identities = 309/1315 (23%), Positives = 525/1315 (39%), Gaps = 134/1315 (10%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 79 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 133
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIAS 1983
C +A+ C G C+C G C+RCAP ++G L G C C+C S
Sbjct: 134 CPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
Query: 1984 EST----QCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMC 2036
+ CD+ GQCR C + TG +C++CA G++ + C CNC G C
Sbjct: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PC 248
Query: 2037 NA-TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
++ TG+C G CP + CD C L ++ L+AL E
Sbjct: 249 DSVTGEC-LEEGFEPPTGMDCPT----------ISCDKCVWDLTDALR-LAALSIEEGKS 296
Query: 2096 FKDKADSFFTTQR-LNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEF 2154
S R +N I+ LL+ K+++ + I E + K+LL E
Sbjct: 297 GVLSVSSGAAAHRHVNEINATIYLLKTKLSEREN-QYALRKIQINNAENTMKSLLSDVE- 354
Query: 2155 AATDSDKQISRAAKLAE----DAERTLAAVRESAREATEVVKHVAD--LATGLELSQQPK 2208
+ + Q SR +L + D + + E A + + ++ + + L G E PK
Sbjct: 355 ELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPK 414
Query: 2209 -VDSALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRP 2267
+ L A+++ ++I + P Q E V E ++ Q + Q + R
Sbjct: 415 EISEKLVLAQKMLEEIRSRQ--PFFTQRELVDEEADEAYELLS---QAESWQRLHNETRT 469
Query: 2268 DLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNSVTKLNTA 2327
F ++ + KL D+ E D A + AE++N R + + + +
Sbjct: 470 --LFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMN---RATAARQRDHEKQQERVR 524
Query: 2328 AMGDLIDAAYDIG-NATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEH 2386
++++ + ++ L H
Sbjct: 525 EQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSH 584
Query: 2387 -LTSEATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXX 2445
L EA HA L++ A+ L + N Q ++
Sbjct: 585 DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFA 644
Query: 2446 XXXXXNVTKLNRILDERVRPARERSSSLLADA----TKAQHAVDQKLLPNLTATEEVLRK 2501
+ +D ++ ++ S +LL A KA+ + D+ + L +
Sbjct: 645 LNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALAR 704
Query: 2502 IRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKD 2561
+R D +Q + N T T V P +
Sbjct: 705 KSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRT---TMEVQQATAPMANNLTN 761
Query: 2562 WAQTLPKLADEGQKMTSN-VESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQ 2620
W+Q L N ++N+ ++ PQ+ TV+ +Q
Sbjct: 762 WSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSAS-----IQ 816
Query: 2621 KLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR--------TK 2672
++++L+ Q R+VA++IQV + FD S ++ ++D++ T +S Y + T+
Sbjct: 817 RIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTE 876
Query: 2673 EKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMV 2732
D FILYLG+ + +YM + I+N V ++G + +D
Sbjct: 877 TADQFILYLGS-------KNAKKEYMGLAIKNDNLVYVYNLGTKD------VEIPLDSKP 923
Query: 2733 ADN--RWYQVI-VDRLGRRVKLSIR-ESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLY 2788
+ ++ ++ ++R+G+ K+ + SL + + K+ + G ++ +LD E + Y
Sbjct: 924 VSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFY 983
Query: 2789 VGGVPSDAKL-QGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQ----RDKLISS 2843
VGGVPS+ KL ++ P F G +E + + + L+NF + + RDKL +
Sbjct: 984 VGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFT 1043
Query: 2844 QSGPQEYRFDGRGYATMAG--RGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
QS Y FDG GYA + R Q + + RT A NGLI L+ G FF L M+
Sbjct: 1044 QSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMR 1103
Query: 2902 DGRVYLQVSLGNTEDLIIVGTT---RAYNDGKWHKLD-ARRFLAKCSLTVDNEVLKAESN 2957
+G +++ G + + + T ND K+H++ K L VD +K+ N
Sbjct: 1104 NGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDN 1163
Query: 2958 SPSADIPSLDTMNFGGNNKGILQ-------VP-DRGFDGCMRQISINGVNLDLSENLESI 3009
IP D + GG ILQ +P D F GCM+ + +L E E++
Sbjct: 1164 E-KMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETL 1221
Query: 3010 GMAYGCQFASLVS----FNGTDSYLRFVDVTS--ENPQLTLKFKTAKPNGLLFVYVSRTQ 3063
G+ YGC SL+S FNG S++ + S + + F+T +PNGLLF Y S +
Sbjct: 1222 GVGYGCPEDSLISRRAYFNG-QSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGS- 1279
Query: 3064 TAIMPDSISLSLVNGKLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVD 3118
D S+SL NG +++ + ++ + YND H + + + + +L+VD
Sbjct: 1280 -----DVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1329
Score = 206 bits (503), Expect = 1e-51
Identities = 94/204 (46%), Positives = 120/204 (58%), Gaps = 11/204 (5%)
Query: 1746 SCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
+ E+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G P+ C C CP+P+ + NFA SC +NG+ + C C Y G CE CA GYYG P
Sbjct: 123 RGAPQFCQPCPCPLPHLA-NFAESC-YRKNGA-VRCICNENYAGPNCERCAPGYYGNP-- 177
Query: 1866 TDLHTGDYCKPCNCSGNINPQ-DPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
L G CK C+CSGN +P CD + G C C+ NT G C CAPG+YGDA +
Sbjct: 178 --LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1925 KNCTACICDEFGMADCDSTTGTCV 1948
KNC C C G CDS TG C+
Sbjct: 236 KNCAVCNC---GGGPCDSVTGECL 256
Score = 146 bits (353), Expect = 2e-33
Identities = 105/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 1470 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 1525
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S YND WH V R G+L +D V E S+
Sbjct: 1526 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1585
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 1586 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 1644
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 1645 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1700
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 1701 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 1757
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 1758 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1816
Query: 3662 VGVCP 3666
+ CP
Sbjct: 1817 INSCP 1821
Score = 105 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 31/204 (15%)
Query: 387 PPDCSSCAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGY 443
PP C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 444 Y------SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQCQAGYYNYP 492
+P+ C+ C C + + + C + G C C Y+G C +C GYY P
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 493 -----TCKPCNCDTSGTEPSI----CDDVSGQC-ICKAGFGGPRCDQCLSGYYMQVLGRE 542
TCK C+C + ++P++ CD+V+GQC C G +C++C GYY
Sbjct: 178 LLIGSTCKKCDC-SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIA 235
Query: 543 RQCVPCNC--DPTGSTSTSCSADG 564
+ C CNC P S + C +G
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEG 259
Score = 99 bits (238), Expect = 1e-19
Identities = 66/200 (33%), Positives = 86/200 (43%), Gaps = 40/200 (20%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 79 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 348 YGKRWDELDVCQPCQCD-PHFS--TGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
+ + CQPC C PH + +C ++G RC C + P+C CA GY+ P
Sbjct: 121 SIRGAPQF--CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Query: 402 ----NCKPCTCNLNGTEG---EHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE--CKNC 451
CK C C+ N E C G C C N G CE C GYY KNC
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
Query: 452 E-CNTVGSVSYVCDKLTGDC 470
CN G CD +TG+C
Sbjct: 239 AVCNCGGG---PCDSVTGEC 255
Score = 90.2 bits (214), Expect = 1e-16
Identities = 63/197 (31%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 435 SCEICEDGYY---SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGYYN 490
+ E C G++ S EC C+CN G+ S C +G C C+ +G C +C GY
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCN--GN-SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 491 YPT------CKPCNCDTS--GTEPSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLG 540
C+PC C C +G +CIC + GP C++C GYY L
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 541 RERQCVPCNC----DPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
C C+C DP G+C NCL N G +C++C+PGYY ++ NC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 596 DVSGSIGSTCDD-NGLC 611
V G CD G C
Sbjct: 239 AVCNCGGGPCDSVTGEC 255
Score = 82.6 bits (195), Expect = 2e-14
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 67 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVPGHYAFP-----DCY 1476
C C C PL + N + C +G +C C EN G C+ C PG+Y P C
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
Query: 1477 QCTCNRH---GTTYDVCDQNTAQC-YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCF 1532
+C C+ + ++ CD+ T QC C N G C+ C Y+ C C C
Sbjct: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
Query: 1533 G 1533
G
Sbjct: 245 G 245
Score = 79.8 bits (188), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 1729 RATSVEECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCNGHSD------QCDVNTG 1779
R C C Y G +CE+CA G+Y P C C C+G+SD CD TG
Sbjct: 148 RKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
Score = 77.4 bits (182), Expect = 9e-13
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 28/174 (16%)
Query: 1738 CPRAYRGLSCEQCAEGH----YRLPSGFCVPCQC-----NGHSDQCDVNTGI--CLNCAD 1786
C R G CE+C +G+ R FC PC C ++ C G C+ C +
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNE 159
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
N G +CE C GY+G+ + C C C N CD G NC
Sbjct: 160 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCD-EVTGQ--CRNCLRN 215
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 216 TTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 257
Score = 76.6 bits (180), Expect = 2e-12
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%)
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPG 583
P ++C +G++ + G +CVPC+C+ G+++ G C +C N G C++C G
Sbjct: 62 PAAEKCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 584 YYK-----YPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCDTCREQFYNY 632
Y P C C C + + +C NG C C N+ G C+ C +Y
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 633 P-----ACEECNCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
P C++C+C F C V G+ C G C C P Y+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEV-TGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 687 PFGCEQCNCNLAGTLNSL-GACNTKSGQCVCKQHVGERQCDQCL 729
C CNC G +S+ G C + + CD+C+
Sbjct: 236 K-NCAVCNCG-GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
Score = 76.2 bits (179), Expect = 2e-12
Identities = 55/180 (30%), Positives = 75/180 (41%), Gaps = 30/180 (16%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY-----GFPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 82 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 140
Query: 1395 D-------DNG--MCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGVVGNQLQ 1443
+ NG CIC +N G NC+RC P + + G C C+C+ +
Sbjct: 141 NFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFE 200
Query: 1444 -CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 255
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 1909 ACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG 1967
A C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 63 AAEKCNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 1968 ---LNTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN---Y 2016
C PC C +A+ + C NG +C C + G C++CA G++
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 2017 TKDGCDHCNCNTGYSVGFM---CN-ATGQC-ECLPGVIGEKCDRC 2056
C C+C+ + C+ TGQC CL G KC+RC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + YND
Sbjct: 1493 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYND 1550
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 1551 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 1610
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 1611 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 1666
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 1667 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 1724
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 1725 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 1782
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 1783 LAPSKPFTGCIRHFVIDG 1800
Score = 68.9 bits (161), Expect = 3e-10
Identities = 59/204 (28%), Positives = 78/204 (38%), Gaps = 39/204 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 82 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 131
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + S R G +C+ C N G NC +C P Y YG
Sbjct: 132 CPCPL--------PHLANFAESC---YRKNGAVRCI-CNENYAGPNCERCAPGY---YGN 176
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFD----YP 401
C+ C C DP+ +C+E +G+C C C CA GY+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLC 425
NC C C G C G C
Sbjct: 237 NCAVCNCG-----GGPCDSVTGEC 255
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY-WN 681
+ C F++ + E CD G + GS G C+ G C C Y +
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLD-GS---GYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHVGERQCDQCLDGFYRLQTND 739
P C+ C C L N +C K+G +C+C ++ C++C G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 740 VFGCTECDCDIGGSIDN----NCDKTTGQC-HCHSRVEGRRCDQPIRAHY 784
C +CDC G S N +CD+ TGQC +C G +C++ +Y
Sbjct: 181 GSTCKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 56.0 bits (129), Expect = 2e-06
Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 26/140 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C N GP C +C G+ I +C+ C+C ++ DP + +
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNL----IFE 200
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D + E G+C NC NT G C +C P YY + C C C G C+
Sbjct: 201 DCD---EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCD 249
Query: 374 EESGRCECRPEFQPPDCSSC 393
+G C F+PP C
Sbjct: 250 SVTGEC-LEEGFEPPTGMDC 268
Score = 55.2 bits (127), Expect = 4e-06
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 17/111 (15%)
Query: 1339 PCLCDFMGSTELECNTFGG--QCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHCPST 1391
PC + + C G +C C N G C C GYYG P C+ C C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN 192
Query: 1392 A-------ICDD-NGMC-ICPKNVEGENCDRCKP-YTFNFDVQRGCDDCNC 1432
+ CD+ G C C +N G C+RC P Y + + + C CNC
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC 243
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 3041 QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV---VSQREQLDTGLNTYN 3097
Q +++ +T +G++F YVS + D ++L L +G+LV V ++ YN
Sbjct: 1494 QFSIRLRTRSSHGMIF-YVSDQEEN---DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYN 1549
Query: 3098 DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAP-PPLHILDGVLFIGGVQPGYVVSG-SLG 3155
D WH + S+ +LV+D P + G +++GGV PG V +
Sbjct: 1550 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQIN 1609
Query: 3156 SKVPFTGCIGDATING-QVLNLLEPFSNNSVTFG--RCGTTITTGG 3198
S F+GC+ + +NG + + + FS G GT +T G
Sbjct: 1610 SIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEG 1655
Score = 46.0 bits (104), Expect = 0.003
Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 1488 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 1539
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + D W+ VI R +L I D + E LP
Sbjct: 1540 ------LKIRSQEKYNDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 1585
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 1586 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 1631
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 1632 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 1688
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 1689 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 1748
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 1749 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1807
Score = 38.7 bits (86), Expect = 0.39
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN---------TGY 2030
G ++ Q + + R A G ++C AGF++ C C+CN +GY
Sbjct: 38 GSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGY 97
Query: 2031 SVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
V N TG+ CE CL G IG+ P+
Sbjct: 98 CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
>AL031316-2|CAI20062.1| 1172|Homo sapiens laminin, beta 3 protein.
Length = 1172
Score = 263 bits (644), Expect = 1e-68
Identities = 160/518 (30%), Positives = 242/518 (46%), Gaps = 55/518 (10%)
Query: 58 WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQ 117
WWQS N V+L +DL + F + V ++ P P ++E+S+D+GKT++ +Q
Sbjct: 94 WWQSQN-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQ 147
Query: 118 YFSDSPQDCERYFGK-ESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
Y + DC F + +P + D S L G++ ++L+ D S
Sbjct: 148 YLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLM-DLVSGIPAT 203
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S +QE TN+R+ R L + P+ +Y++ + + G C C+GH
Sbjct: 204 QSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGH 255
Query: 237 ADTCEP-----ADPAGNLNIL-VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
AD C P A P+ + + VC CQHNT GP C +C + + WR ++ D C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR 315
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C+ H+ C +DP + G Y GG C NC+ +TEG NC +C+ Y+R
Sbjct: 316 CDCNGHSETCHFDPAVFAAS-----QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 351 RWDELDVCQPCQCDPHFST--GNCEEESGRCECRPEFQPPDCSSCAYGY--FDYPN---C 403
+ C C+CDP + C+ +G+C C+ Q C C G+ Y N C
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 404 KPCTCNLNGTEGE-HCTPTDGLCPCKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
C CN+ G+ + C G C C N G C+ C ++ C+ C C+ S
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCN-----QC-QAGYYNYPT-CKPCNCDTSGTEPSICDD 511
+S C++ TG C C+ + G C+ QC Y + T C+ C+CD GTE CD
Sbjct: 489 LSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
SG+C+C+ G GPRCDQC GY R CV C+
Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGY----CNRYPVCVACH 582
Score = 169 bits (412), Expect = 1e-40
Identities = 107/341 (31%), Positives = 152/341 (44%), Gaps = 37/341 (10%)
Query: 1765 CQCNGHSDQCDVNTG-------------ICLNCADNTIGDHCEFCMSGYHG----DATVG 1807
C C+GH+D+C G +C+ C NT G +CE C Y+ A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1808 TPRDCLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIPED 1865
+C C C + +F + + G+ + NC+ G CE C Y+
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR-NRR 367
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
+ C C C + PG+ CD + G C+ C + G C+LC PGF G +
Sbjct: 368 PGASIQETCISCECDPD--GAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYAN 424
Query: 1925 -KNCTACICDEFGMA---DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG 1980
+ C C C+ G CD +G C+C P V+G KCD+CAP HW L +G GC PC C
Sbjct: 425 PQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1981 -IASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCDHCNCNTGYSVGF 2034
S S QC+ GQC C +G G C QC + GC C+C+ + G
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 2035 MCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
C+ A+G+C C PG+ G +CD+C +R C+ C C
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQC-QRGYCNRYPVCVACHPC 584
Score = 160 bits (389), Expect = 8e-38
Identities = 99/307 (32%), Positives = 138/307 (44%), Gaps = 49/307 (15%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTPT------- 421
C C+ P+C CA Y + P C+ C CN +E H P
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQG 337
Query: 422 --DGLCP-CKYNYAGKSCEICEDGYY---------SPECKNCECNTVGSVSYV-CDKLTG 468
G+C C+ + GK+CE C+ Y+ C +CEC+ G+V CD +TG
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 469 DCTCKSKYSGRTCNQCQAG-----YYNYPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGF 522
C CK G C+ C+ G Y N C C+C+ G+ + CD+ SG+C+C
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCD--- 578
GP+CDQC ++ G+ C PC CDP S S C+ G+C C FGG C
Sbjct: 458 VGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Query: 579 --QCSPGYYK--YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYN-Y 632
QC Y C +C+CD G+ G CD +G C C+ G +CD C+ + N Y
Sbjct: 516 IRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRY 575
Query: 633 PACEECN 639
P C C+
Sbjct: 576 PVCVACH 582
Score = 147 bits (357), Expect = 6e-34
Identities = 98/314 (31%), Positives = 138/314 (43%), Gaps = 47/314 (14%)
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNC---------D 551
PS V C+C+ GP C++C Y + G++ +C C+C D
Sbjct: 269 PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFD 328
Query: 552 PTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYK--------YPDCLSCNCDVSGSI- 601
P ++ + G C NC + G C++C Y++ C+SC CD G++
Sbjct: 329 PAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 602 GSTCDD-NGLCHCKSNFDGAKCDTCREQF----YNYP-ACEECNCDPRGVTASFAGCGSV 655
G+ CD G C CK + G +CD C+ F Y P C C+C+ G C
Sbjct: 389 GAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMP-CDE- 446
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
+G C C V G C+ C P +W L GCE C C+ +L+ CN +GQC
Sbjct: 447 ESGR-CLCLPNVVGPKCDQCAPYHWKLASGQ--GCEPCACDPHNSLSP--QCNQFTGQCP 501
Query: 716 CKQHVGERQCD-----QCLDGFYRLQTNDVF-GCTECDCDIGGSIDNNCDKTTGQCHCHS 769
C++ G C QC D Y DV GC CDCD G+ CDK +G+C C
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTY----GDVATGCRACDCDFRGTEGPGCDKASGRCLCRP 557
Query: 770 RVEGRRCDQPIRAH 783
+ G RCDQ R +
Sbjct: 558 GLTGPRCDQCQRGY 571
Score = 145 bits (352), Expect = 2e-33
Identities = 92/300 (30%), Positives = 128/300 (42%), Gaps = 46/300 (15%)
Query: 424 LCPCKYNYAGKSCEICE-----------DGYYSPECKNCECNTVGSVSYVCDKLT----- 467
+C C++N AG +CE C +G + EC+ C+CN + +
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 468 ---GDC-TCKSKYSGRTCNQCQAGYYN--------YPTCKPCNCDTSGTEPSI-CDDVSG 514
G C C+ G+ C +CQ Y+ TC C CD G P CD V+G
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNF 572
QC+CK G RCD C G+ + C C+C+ GS C + G+C CL N
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 573 GGAQCDQCSPGYYKYPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT---- 624
G +CDQC+P ++K C C CD S+ C+ G C C+ F G C
Sbjct: 458 VGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIR 517
Query: 625 -CREQFYNYPA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C ++ Y A C C+CD RG GC A C C+ + G C+ C+ Y N
Sbjct: 518 QCPDRTYGDVATGCRACDCDFRGTEGP--GCDK--ASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 139 bits (336), Expect = 2e-31
Identities = 92/309 (29%), Positives = 126/309 (40%), Gaps = 43/309 (13%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G +CE+CA + P + C C CNGHS+ C +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDATVGT--PRDCLICACPMPYPSNNF-ALSCDLS 1833
G+C NC D+T G +CE C Y + G C+ C C P CD
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD---PDGAVPGAPCDPV 395
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
C C+ G RC+ C G+ G+ C C+C+ + + CD
Sbjct: 396 TG----QCVCKEHVQGERCDLCKPGFTGL----TYANPQGCHRCDCN-ILGSRRDMPCDE 446
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRP 1951
+G CL C+ N G C+ CAP ++ + C C CD C+ TG C CR
Sbjct: 447 ESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 1952 GVIGEKCDRCA----PDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQC 2006
G G C A PD + GC C+C +E CD +G+C C G+TG +C
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 2007 DQCAAGFWN 2015
DQC G+ N
Sbjct: 565 DQCQRGYCN 573
Score = 117 bits (282), Expect = 7e-25
Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 1340 CLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-CPSTAI-- 1393
C CD G+ C+ GQC CK +V G C C+ G+ G P CH C +
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1394 -----CDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
CD+ +G C+C NV G CD+C PY + +GC+ C C+P + QC
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP--QCNQF 496
Query: 1448 SGKCACRENVRGRVCD-----HCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCK 1500
+G+C CRE G +C C Y C C C+ GT CD+ + +C C+
Sbjct: 497 TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
Query: 1501 TNVRGQACDTCKEEYFN 1517
+ G CD C+ Y N
Sbjct: 557 PGLTGPRCDQCQRGYCN 573
Score = 103 bits (248), Expect = 9e-21
Identities = 61/194 (31%), Positives = 87/194 (44%), Gaps = 20/194 (10%)
Query: 610 LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVT-----ASFAGCGS 654
+C C+ N G C+ C + N P C+ C+C+ T A FA
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLGACNTKS 711
G C+D +G+ C C+ Y+ + C C C+ G + C+ +
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPG-APCDPVT 396
Query: 712 GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS-IDNNCDKTTGQCHCHSR 770
GQCVCK+HV +CD C GF L + GC CDC+I GS D CD+ +G+C C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 771 VEGRRCDQPIRAHY 784
V G +CDQ H+
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 103 bits (246), Expect = 2e-20
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 38/208 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC----------PSTAICDDN- 1397
C C+ N G C C Y P C+ C C P+
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1398 --GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
G+C C + EG+NC+RC+ + F +Q C C C+P G V C+ +G
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-PCDPVTG 397
Query: 1450 KCACRENVRGRVCDHCVPGH----YAFPD-CYQCTCNRHGTTYDV-CDQNTAQCYCKTNV 1503
+C C+E+V+G CD C PG YA P C++C CN G+ D+ CD+ + +C C NV
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 1504 RGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
G CD C ++ L + GC C C
Sbjct: 458 VGPKCDQCAPYHWKLA--SGQGCEPCAC 483
Score = 89.8 bits (213), Expect = 2e-16
Identities = 53/181 (29%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCS 1371
++ LC+ +T G C C+ +GS ++ C+ G+C C PNV+G C
Sbjct: 404 HVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCD 463
Query: 1372 ACRTGYYGFPN---CRPCHC-PSTAI---CDD-NGMCICPKNVEGENCD-----RCKPYT 1418
C ++ + C PC C P ++ C+ G C C + G C +C T
Sbjct: 464 QCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRT 523
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQ 1477
+ DV GC C+C+ G G C+ SG+C CR + G CD C G+ +P C
Sbjct: 524 YG-DVATGCRACDCDFRGTEGP--GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 1478 C 1478
C
Sbjct: 581 C 581
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/166 (31%), Positives = 71/166 (42%), Gaps = 24/166 (14%)
Query: 1389 PSTAICDDNGMCICPKNVEGENCDRCKPYTFN--FDVQRGCDDCNCNPLGVVGNQLQCEA 1446
PSTA+ + +C+C N G NC+RC P+ N + G D C G+ C
Sbjct: 269 PSTAV-QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF 327
Query: 1447 D-----------SGKCA-CRENVRGRVCDHCV--------PGHYAFPDCYQCTCNRHGTT 1486
D G C CR++ G+ C+ C PG C C C+ G
Sbjct: 328 DPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV 387
Query: 1487 YDV-CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T QC CK +V+G+ CD CK + L NP GC +C C
Sbjct: 388 PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 66.1 bits (154), Expect = 2e-09
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 13/108 (12%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-----CRTGYYG--FPNCRPCHC 1388
G PC CD S +CN F GQCPC+ G CSA C YG CR C C
Sbjct: 477 GCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDC 536
Query: 1389 PSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
CD +G C+C + G CD+C + Y + V C C
Sbjct: 537 DFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 65.3 bits (152), Expect = 4e-09
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 17/154 (11%)
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY----WNLQE-YNPFGCEQCN 694
C P+ AS +V ++C C+ G C C P Y W E + C++C+
Sbjct: 259 CAPKP-GASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 695 CN-LAGTLNSLGACNTKS-----GQC-VCKQHVGERQCDQCLDGFYRLQTNDVF---GCT 744
CN + T + A S G C C+ H + C++C ++R + C
Sbjct: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 745 ECDCDIGGSIDN-NCDKTTGQCHCHSRVEGRRCD 777
C+CD G++ CD TGQC C V+G RCD
Sbjct: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Score = 53.2 bits (122), Expect = 2e-05
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYG-FPNCRPCH 1387
+G R C CDF G+ C+ G+C C+P + G C C+ GY +P C CH
Sbjct: 529 TGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
>AL023754-1|CAI19989.1| 1172|Homo sapiens laminin, beta 3 protein.
Length = 1172
Score = 263 bits (644), Expect = 1e-68
Identities = 160/518 (30%), Positives = 242/518 (46%), Gaps = 55/518 (10%)
Query: 58 WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQ 117
WWQS N V+L +DL + F + V ++ P P ++E+S+D+GKT++ +Q
Sbjct: 94 WWQSQN-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQ 147
Query: 118 YFSDSPQDCERYFGK-ESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
Y + DC F + +P + D S L G++ ++L+ D S
Sbjct: 148 YLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLM-DLVSGIPAT 203
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S +QE TN+R+ R L + P+ +Y++ + + G C C+GH
Sbjct: 204 QSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGH 255
Query: 237 ADTCEP-----ADPAGNLNIL-VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
AD C P A P+ + + VC CQHNT GP C +C + + WR ++ D C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR 315
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C+ H+ C +DP + G Y GG C NC+ +TEG NC +C+ Y+R
Sbjct: 316 CDCNGHSETCHFDPAVFAAS-----QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 351 RWDELDVCQPCQCDPHFST--GNCEEESGRCECRPEFQPPDCSSCAYGY--FDYPN---C 403
+ C C+CDP + C+ +G+C C+ Q C C G+ Y N C
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 404 KPCTCNLNGTEGE-HCTPTDGLCPCKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
C CN+ G+ + C G C C N G C+ C ++ C+ C C+ S
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCN-----QC-QAGYYNYPT-CKPCNCDTSGTEPSICDD 511
+S C++ TG C C+ + G C+ QC Y + T C+ C+CD GTE CD
Sbjct: 489 LSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
SG+C+C+ G GPRCDQC GY R CV C+
Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGY----CNRYPVCVACH 582
Score = 169 bits (412), Expect = 1e-40
Identities = 107/341 (31%), Positives = 152/341 (44%), Gaps = 37/341 (10%)
Query: 1765 CQCNGHSDQCDVNTG-------------ICLNCADNTIGDHCEFCMSGYHG----DATVG 1807
C C+GH+D+C G +C+ C NT G +CE C Y+ A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1808 TPRDCLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIPED 1865
+C C C + +F + + G+ + NC+ G CE C Y+
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR-NRR 367
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
+ C C C + PG+ CD + G C+ C + G C+LC PGF G +
Sbjct: 368 PGASIQETCISCECDPD--GAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYAN 424
Query: 1925 -KNCTACICDEFGMA---DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG 1980
+ C C C+ G CD +G C+C P V+G KCD+CAP HW L +G GC PC C
Sbjct: 425 PQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1981 -IASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCDHCNCNTGYSVGF 2034
S S QC+ GQC C +G G C QC + GC C+C+ + G
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 2035 MCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
C+ A+G+C C PG+ G +CD+C +R C+ C C
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQC-QRGYCNRYPVCVACHPC 584
Score = 160 bits (389), Expect = 8e-38
Identities = 99/307 (32%), Positives = 138/307 (44%), Gaps = 49/307 (15%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTPT------- 421
C C+ P+C CA Y + P C+ C CN +E H P
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQG 337
Query: 422 --DGLCP-CKYNYAGKSCEICEDGYY---------SPECKNCECNTVGSVSYV-CDKLTG 468
G+C C+ + GK+CE C+ Y+ C +CEC+ G+V CD +TG
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 469 DCTCKSKYSGRTCNQCQAG-----YYNYPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGF 522
C CK G C+ C+ G Y N C C+C+ G+ + CD+ SG+C+C
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCD--- 578
GP+CDQC ++ G+ C PC CDP S S C+ G+C C FGG C
Sbjct: 458 VGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Query: 579 --QCSPGYYK--YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYN-Y 632
QC Y C +C+CD G+ G CD +G C C+ G +CD C+ + N Y
Sbjct: 516 IRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRY 575
Query: 633 PACEECN 639
P C C+
Sbjct: 576 PVCVACH 582
Score = 147 bits (357), Expect = 6e-34
Identities = 98/314 (31%), Positives = 138/314 (43%), Gaps = 47/314 (14%)
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNC---------D 551
PS V C+C+ GP C++C Y + G++ +C C+C D
Sbjct: 269 PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFD 328
Query: 552 PTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYK--------YPDCLSCNCDVSGSI- 601
P ++ + G C NC + G C++C Y++ C+SC CD G++
Sbjct: 329 PAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 602 GSTCDD-NGLCHCKSNFDGAKCDTCREQF----YNYP-ACEECNCDPRGVTASFAGCGSV 655
G+ CD G C CK + G +CD C+ F Y P C C+C+ G C
Sbjct: 389 GAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMP-CDE- 446
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
+G C C V G C+ C P +W L GCE C C+ +L+ CN +GQC
Sbjct: 447 ESGR-CLCLPNVVGPKCDQCAPYHWKLASGQ--GCEPCACDPHNSLSP--QCNQFTGQCP 501
Query: 716 CKQHVGERQCD-----QCLDGFYRLQTNDVF-GCTECDCDIGGSIDNNCDKTTGQCHCHS 769
C++ G C QC D Y DV GC CDCD G+ CDK +G+C C
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTY----GDVATGCRACDCDFRGTEGPGCDKASGRCLCRP 557
Query: 770 RVEGRRCDQPIRAH 783
+ G RCDQ R +
Sbjct: 558 GLTGPRCDQCQRGY 571
Score = 145 bits (352), Expect = 2e-33
Identities = 92/300 (30%), Positives = 128/300 (42%), Gaps = 46/300 (15%)
Query: 424 LCPCKYNYAGKSCEICE-----------DGYYSPECKNCECNTVGSVSYVCDKLT----- 467
+C C++N AG +CE C +G + EC+ C+CN + +
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 468 ---GDC-TCKSKYSGRTCNQCQAGYYN--------YPTCKPCNCDTSGTEPSI-CDDVSG 514
G C C+ G+ C +CQ Y+ TC C CD G P CD V+G
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNF 572
QC+CK G RCD C G+ + C C+C+ GS C + G+C CL N
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 573 GGAQCDQCSPGYYKYPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT---- 624
G +CDQC+P ++K C C CD S+ C+ G C C+ F G C
Sbjct: 458 VGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIR 517
Query: 625 -CREQFYNYPA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C ++ Y A C C+CD RG GC A C C+ + G C+ C+ Y N
Sbjct: 518 QCPDRTYGDVATGCRACDCDFRGTEGP--GCDK--ASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 139 bits (336), Expect = 2e-31
Identities = 92/309 (29%), Positives = 126/309 (40%), Gaps = 43/309 (13%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G +CE+CA + P + C C CNGHS+ C +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDATVGT--PRDCLICACPMPYPSNNF-ALSCDLS 1833
G+C NC D+T G +CE C Y + G C+ C C P CD
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD---PDGAVPGAPCDPV 395
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
C C+ G RC+ C G+ G+ C C+C+ + + CD
Sbjct: 396 TG----QCVCKEHVQGERCDLCKPGFTGL----TYANPQGCHRCDCN-ILGSRRDMPCDE 446
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRP 1951
+G CL C+ N G C+ CAP ++ + C C CD C+ TG C CR
Sbjct: 447 ESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 1952 GVIGEKCDRCA----PDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQC 2006
G G C A PD + GC C+C +E CD +G+C C G+TG +C
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 2007 DQCAAGFWN 2015
DQC G+ N
Sbjct: 565 DQCQRGYCN 573
Score = 117 bits (282), Expect = 7e-25
Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 21/197 (10%)
Query: 1340 CLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-CPSTAI-- 1393
C CD G+ C+ GQC CK +V G C C+ G+ G P CH C +
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1394 -----CDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
CD+ +G C+C NV G CD+C PY + +GC+ C C+P + QC
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP--QCNQF 496
Query: 1448 SGKCACRENVRGRVCD-----HCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCK 1500
+G+C CRE G +C C Y C C C+ GT CD+ + +C C+
Sbjct: 497 TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
Query: 1501 TNVRGQACDTCKEEYFN 1517
+ G CD C+ Y N
Sbjct: 557 PGLTGPRCDQCQRGYCN 573
Score = 103 bits (248), Expect = 9e-21
Identities = 61/194 (31%), Positives = 87/194 (44%), Gaps = 20/194 (10%)
Query: 610 LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVT-----ASFAGCGS 654
+C C+ N G C+ C + N P C+ C+C+ T A FA
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLGACNTKS 711
G C+D +G+ C C+ Y+ + C C C+ G + C+ +
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPG-APCDPVT 396
Query: 712 GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS-IDNNCDKTTGQCHCHSR 770
GQCVCK+HV +CD C GF L + GC CDC+I GS D CD+ +G+C C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 771 VEGRRCDQPIRAHY 784
V G +CDQ H+
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 103 bits (246), Expect = 2e-20
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 38/208 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC----------PSTAICDDN- 1397
C C+ N G C C Y P C+ C C P+
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1398 --GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
G+C C + EG+NC+RC+ + F +Q C C C+P G V C+ +G
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-PCDPVTG 397
Query: 1450 KCACRENVRGRVCDHCVPGH----YAFPD-CYQCTCNRHGTTYDV-CDQNTAQCYCKTNV 1503
+C C+E+V+G CD C PG YA P C++C CN G+ D+ CD+ + +C C NV
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 1504 RGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
G CD C ++ L + GC C C
Sbjct: 458 VGPKCDQCAPYHWKLA--SGQGCEPCAC 483
Score = 89.8 bits (213), Expect = 2e-16
Identities = 53/181 (29%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCS 1371
++ LC+ +T G C C+ +GS ++ C+ G+C C PNV+G C
Sbjct: 404 HVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCD 463
Query: 1372 ACRTGYYGFPN---CRPCHC-PSTAI---CDD-NGMCICPKNVEGENCD-----RCKPYT 1418
C ++ + C PC C P ++ C+ G C C + G C +C T
Sbjct: 464 QCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRT 523
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQ 1477
+ DV GC C+C+ G G C+ SG+C CR + G CD C G+ +P C
Sbjct: 524 YG-DVATGCRACDCDFRGTEGP--GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 1478 C 1478
C
Sbjct: 581 C 581
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/166 (31%), Positives = 71/166 (42%), Gaps = 24/166 (14%)
Query: 1389 PSTAICDDNGMCICPKNVEGENCDRCKPYTFN--FDVQRGCDDCNCNPLGVVGNQLQCEA 1446
PSTA+ + +C+C N G NC+RC P+ N + G D C G+ C
Sbjct: 269 PSTAV-QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF 327
Query: 1447 D-----------SGKCA-CRENVRGRVCDHCV--------PGHYAFPDCYQCTCNRHGTT 1486
D G C CR++ G+ C+ C PG C C C+ G
Sbjct: 328 DPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV 387
Query: 1487 YDV-CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T QC CK +V+G+ CD CK + L NP GC +C C
Sbjct: 388 PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 66.1 bits (154), Expect = 2e-09
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 13/108 (12%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-----CRTGYYG--FPNCRPCHC 1388
G PC CD S +CN F GQCPC+ G CSA C YG CR C C
Sbjct: 477 GCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDC 536
Query: 1389 PSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
CD +G C+C + G CD+C + Y + V C C
Sbjct: 537 DFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
Score = 65.3 bits (152), Expect = 4e-09
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 17/154 (11%)
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY----WNLQE-YNPFGCEQCN 694
C P+ AS +V ++C C+ G C C P Y W E + C++C+
Sbjct: 259 CAPKP-GASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 695 CN-LAGTLNSLGACNTKS-----GQC-VCKQHVGERQCDQCLDGFYRLQTNDVF---GCT 744
CN + T + A S G C C+ H + C++C ++R + C
Sbjct: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 745 ECDCDIGGSIDN-NCDKTTGQCHCHSRVEGRRCD 777
C+CD G++ CD TGQC C V+G RCD
Sbjct: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Score = 53.2 bits (122), Expect = 2e-05
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYG-FPNCRPCH 1387
+G R C CDF G+ C+ G+C C+P + G C C+ GY +P C CH
Sbjct: 529 TGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
>AB210027-1|BAE06109.1| 1852|Homo sapiens LAMA4 variant protein
protein.
Length = 1852
Score = 262 bits (643), Expect = 1e-68
Identities = 309/1315 (23%), Positives = 524/1315 (39%), Gaps = 134/1315 (10%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 108 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 162
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIAS 1983
C +A+ C G C+C G C+RCAP ++G L G C C+C S
Sbjct: 163 CPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 222
Query: 1984 EST----QCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMC 2036
+ CD+ GQCR C + TG +C++CA G++ + C CNC G C
Sbjct: 223 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PC 277
Query: 2037 NA-TGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
++ TG+C G CP + CD C L + L+AL E
Sbjct: 278 DSVTGEC-LEEGFEPPTGMDCPT----------ISCDKCVWDLTDDLR-LAALSIEEGKS 325
Query: 2096 FKDKADSFFTTQR-LNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEF 2154
S R +N I+ LL+ K+++ + I E + K+LL E
Sbjct: 326 GVLSVSSGAAAHRHVNEINATIYLLKTKLSEREN-QYALRKIQINNAENTMKSLLSDVE- 383
Query: 2155 AATDSDKQISRAAKLAE----DAERTLAAVRESAREATEVVKHVAD--LATGLELSQQPK 2208
+ + Q SR +L + D + + E A + + ++ + + L G E PK
Sbjct: 384 ELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPK 443
Query: 2209 -VDSALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRP 2267
+ L A+++ ++I + P Q E V E ++ Q + Q + R
Sbjct: 444 EISEKLVLAQKMLEEIRSRQ--PFFTQRELVDEEADEAYELLS---QAESWQRLHNETRT 498
Query: 2268 DLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNSVTKLNTA 2327
F ++ + KL D+ E D A + AE++N R + + + +
Sbjct: 499 --LFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMN---RATAARQRDHEKQQERVR 553
Query: 2328 AMGDLIDAAYDIG-NATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEH 2386
++++ + ++ L H
Sbjct: 554 EQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSH 613
Query: 2387 -LTSEATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXX 2445
L EA HA L++ A+ L + N Q ++
Sbjct: 614 DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFA 673
Query: 2446 XXXXXNVTKLNRILDERVRPARERSSSLLADA----TKAQHAVDQKLLPNLTATEEVLRK 2501
+ +D ++ ++ S +LL A KA+ + D+ + L +
Sbjct: 674 LNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALAR 733
Query: 2502 IRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKD 2561
+R D +Q + N T T V P +
Sbjct: 734 KSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRT---TMEVQQATAPMANNLTN 790
Query: 2562 WAQTLPKLADEGQKMTSN-VESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQ 2620
W+Q L N ++N+ ++ PQ+ TV+ +Q
Sbjct: 791 WSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSAS-----IQ 845
Query: 2621 KLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR--------TK 2672
++++L+ Q R+VA++IQV + FD S ++ ++D++ T +S Y + T+
Sbjct: 846 RIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTE 905
Query: 2673 EKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMV 2732
D FILYLG+ + +YM + I+N V ++G + +D
Sbjct: 906 TADQFILYLGS-------KNAKKEYMGLAIKNDNLVYVYNLGTKD------VEIPLDSKP 952
Query: 2733 ADN--RWYQVI-VDRLGRRVKLSIR-ESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLY 2788
+ ++ ++ ++R+G+ K+ + SL + + K+ + G ++ +LD E + Y
Sbjct: 953 VSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFY 1012
Query: 2789 VGGVPSDAKL-QGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQ----RDKLISS 2843
VGGVPS+ KL ++ P F G +E + + + L+NF + + RDKL +
Sbjct: 1013 VGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFT 1072
Query: 2844 QSGPQEYRFDGRGYATMAG--RGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
QS Y FDG GYA + R Q + + RT A NGLI L+ G FF L M+
Sbjct: 1073 QSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMR 1132
Query: 2902 DGRVYLQVSLGNTEDLIIVGTT---RAYNDGKWHKLD-ARRFLAKCSLTVDNEVLKAESN 2957
+G +++ G + + + T ND K+H++ K L VD +K+ N
Sbjct: 1133 NGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDN 1192
Query: 2958 SPSADIPSLDTMNFGGNNKGILQ-------VP-DRGFDGCMRQISINGVNLDLSENLESI 3009
IP D + GG ILQ +P D F GCM+ + +L E E++
Sbjct: 1193 E-KMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETL 1250
Query: 3010 GMAYGCQFASLVS----FNGTDSYLRFVDVTS--ENPQLTLKFKTAKPNGLLFVYVSRTQ 3063
G+ YGC SL+S FNG S++ + S + + F+T +PNGLLF Y S +
Sbjct: 1251 GVGYGCPEDSLISRRAYFNG-QSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGS- 1308
Query: 3064 TAIMPDSISLSLVNGKLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVD 3118
D S+SL NG +++ + ++ + YND H + + + + +L+VD
Sbjct: 1309 -----DVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1358
Score = 206 bits (503), Expect = 1e-51
Identities = 94/204 (46%), Positives = 120/204 (58%), Gaps = 11/204 (5%)
Query: 1746 SCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
+ E+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+
Sbjct: 92 AAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 151
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G P+ C C CP+P+ + NFA SC +NG+ + C C Y G CE CA GYYG P
Sbjct: 152 RGAPQFCQPCPCPLPHLA-NFAESC-YRKNGA-VRCICNENYAGPNCERCAPGYYGNP-- 206
Query: 1866 TDLHTGDYCKPCNCSGNINPQ-DPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
L G CK C+CSGN +P CD + G C C+ NT G C CAPG+YGDA +
Sbjct: 207 --LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 264
Query: 1925 KNCTACICDEFGMADCDSTTGTCV 1948
KNC C C G CDS TG C+
Sbjct: 265 KNCAVCNC---GGGPCDSVTGECL 285
Score = 146 bits (353), Expect = 2e-33
Identities = 105/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 1499 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 1554
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S YND WH V R G+L +D V E S+
Sbjct: 1555 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1614
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 1615 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 1673
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 1674 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1729
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 1730 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 1786
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 1787 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1845
Query: 3662 VGVCP 3666
+ CP
Sbjct: 1846 INSCP 1850
Score = 105 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 31/204 (15%)
Query: 387 PPDCSSCAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGY 443
PP C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 90 PPAAEKCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 146
Query: 444 Y------SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQCQAGYYNYP 492
+P+ C+ C C + + + C + G C C Y+G C +C GYY P
Sbjct: 147 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 206
Query: 493 -----TCKPCNCDTSGTEPSI----CDDVSGQC-ICKAGFGGPRCDQCLSGYYMQVLGRE 542
TCK C+C + ++P++ CD+V+GQC C G +C++C GYY
Sbjct: 207 LLIGSTCKKCDC-SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIA 264
Query: 543 RQCVPCNC--DPTGSTSTSCSADG 564
+ C CNC P S + C +G
Sbjct: 265 KNCAVCNCGGGPCDSVTGECLEEG 288
Score = 99 bits (238), Expect = 1e-19
Identities = 66/200 (33%), Positives = 86/200 (43%), Gaps = 40/200 (20%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 108 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 149
Query: 348 YGKRWDELDVCQPCQCD-PHFS--TGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
+ + CQPC C PH + +C ++G RC C + P+C CA GY+ P
Sbjct: 150 SIRGAPQF--CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 207
Query: 402 ----NCKPCTCNLNGTEG---EHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE--CKNC 451
CK C C+ N E C G C C N G CE C GYY KNC
Sbjct: 208 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 267
Query: 452 E-CNTVGSVSYVCDKLTGDC 470
CN G CD +TG+C
Sbjct: 268 AVCNCGGG---PCDSVTGEC 284
Score = 90.2 bits (214), Expect = 1e-16
Identities = 63/197 (31%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 435 SCEICEDGYY---SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGYYN 490
+ E C G++ S EC C+CN G+ S C +G C C+ +G C +C GY
Sbjct: 92 AAEKCNAGFFHTLSGECVPCDCN--GN-SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 148
Query: 491 YPT------CKPCNCDTS--GTEPSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLG 540
C+PC C C +G +CIC + GP C++C GYY L
Sbjct: 149 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 208
Query: 541 RERQCVPCNC----DPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
C C+C DP G+C NCL N G +C++C+PGYY ++ NC
Sbjct: 209 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 267
Query: 596 DVSGSIGSTCDD-NGLC 611
V G CD G C
Sbjct: 268 AVCNCGGGPCDSVTGEC 284
Score = 82.6 bits (195), Expect = 2e-14
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 96 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 155
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVPGHYAFP-----DCY 1476
C C C PL + N + C +G +C C EN G C+ C PG+Y P C
Sbjct: 156 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 214
Query: 1477 QCTCNRH---GTTYDVCDQNTAQC-YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCF 1532
+C C+ + ++ CD+ T QC C N G C+ C Y+ C C C
Sbjct: 215 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 273
Query: 1533 G 1533
G
Sbjct: 274 G 274
Score = 79.8 bits (188), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 1729 RATSVEECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCNGHSD------QCDVNTG 1779
R C C Y G +CE+CA G+Y P C C C+G+SD CD TG
Sbjct: 177 RKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 236
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 237 QCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 272
Score = 77.4 bits (182), Expect = 9e-13
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 28/174 (16%)
Query: 1738 CPRAYRGLSCEQCAEGH----YRLPSGFCVPCQC-----NGHSDQCDVNTGI--CLNCAD 1786
C R G CE+C +G+ R FC PC C ++ C G C+ C +
Sbjct: 130 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNE 188
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
N G +CE C GY+G+ + C C C N CD G NC
Sbjct: 189 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCD-EVTGQ--CRNCLRN 244
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 245 TTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 286
Score = 77.0 bits (181), Expect = 1e-12
Identities = 62/208 (29%), Positives = 86/208 (41%), Gaps = 34/208 (16%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY-----GFPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 111 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 169
Query: 1395 D-------DNG--MCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGVVGNQLQ 1443
+ NG CIC +N G NC+RC P + + G C C+C+ +
Sbjct: 170 NFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFE 229
Query: 1444 -CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 230 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 284
Query: 1498 YCK--TNVRGQACDT--CKEEYFNLQDD 1521
+ G C T C + ++L DD
Sbjct: 285 LEEGFEPPTGMDCPTISCDKCVWDLTDD 312
Score = 76.6 bits (180), Expect = 2e-12
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%)
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPG 583
P ++C +G++ + G +CVPC+C+ G+++ G C +C N G C++C G
Sbjct: 91 PAAEKCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 145
Query: 584 YYK-----YPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCDTCREQFYNY 632
Y P C C C + + +C NG C C N+ G C+ C +Y
Sbjct: 146 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 205
Query: 633 P-----ACEECNCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
P C++C+C F C V G+ C G C C P Y+
Sbjct: 206 PLLIGSTCKKCDCSGNSDPNLIFEDCDEV-TGQCRNCLRNTTGFKCERCAPGYYGDARIA 264
Query: 687 PFGCEQCNCNLAGTLNSL-GACNTKSGQCVCKQHVGERQCDQCL 729
C CNC G +S+ G C + + CD+C+
Sbjct: 265 K-NCAVCNCG-GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV 306
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 1909 ACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG 1967
A C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 92 AAEKCNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 148
Query: 1968 ---LNTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN---Y 2016
C PC C +A+ + C NG +C C + G C++CA G++
Sbjct: 149 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 208
Query: 2017 TKDGCDHCNCNTGYSVGFM---CN-ATGQC-ECLPGVIGEKCDRC 2056
C C+C+ + C+ TGQC CL G KC+RC
Sbjct: 209 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 253
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + YND
Sbjct: 1522 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYND 1579
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 1580 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 1639
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 1640 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 1695
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 1696 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 1753
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 1754 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 1811
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 1812 LAPSKPFTGCIRHFVIDG 1829
Score = 68.9 bits (161), Expect = 3e-10
Identities = 59/204 (28%), Positives = 78/204 (38%), Gaps = 39/204 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 111 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 160
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + S R G +C+ C N G NC +C P Y YG
Sbjct: 161 CPCPL--------PHLANFAESC---YRKNGAVRCI-CNENYAGPNCERCAPGY---YGN 205
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFD----YP 401
C+ C C DP+ +C+E +G+C C C CA GY+
Sbjct: 206 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 265
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLC 425
NC C C G C G C
Sbjct: 266 NCAVCNCG-----GGPCDSVTGEC 284
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY-WN 681
+ C F++ + E CD G + GS G C+ G C C Y +
Sbjct: 94 EKCNAGFFHTLSGECVPCDCNGNSNECLD-GS---GYCVHCQRNTTGEHCEKCLDGYIGD 149
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHVGERQCDQCLDGFYRLQTND 739
P C+ C C L N +C K+G +C+C ++ C++C G+Y
Sbjct: 150 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 209
Query: 740 VFGCTECDCDIGGSIDN----NCDKTTGQC-HCHSRVEGRRCDQPIRAHY 784
C +CDC G S N +CD+ TGQC +C G +C++ +Y
Sbjct: 210 GSTCKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 258
Score = 56.0 bits (129), Expect = 2e-06
Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 26/140 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C N GP C +C G+ I +C+ C+C ++ DP + +
Sbjct: 184 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNL----IFE 229
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D + E G+C NC NT G C +C P YY + C C C G C+
Sbjct: 230 DCD---EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCD 278
Query: 374 EESGRCECRPEFQPPDCSSC 393
+G C F+PP C
Sbjct: 279 SVTGEC-LEEGFEPPTGMDC 297
Score = 55.2 bits (127), Expect = 4e-06
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 17/111 (15%)
Query: 1339 PCLCDFMGSTELECNTFGG--QCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHCPST 1391
PC + + C G +C C N G C C GYYG P C+ C C
Sbjct: 162 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN 221
Query: 1392 A-------ICDD-NGMC-ICPKNVEGENCDRCKP-YTFNFDVQRGCDDCNC 1432
+ CD+ G C C +N G C+RC P Y + + + C CNC
Sbjct: 222 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC 272
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 3041 QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV---VSQREQLDTGLNTYN 3097
Q +++ +T +G++F YVS + D ++L L +G+LV V ++ YN
Sbjct: 1523 QFSIRLRTRSSHGMIF-YVSDQEEN---DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYN 1578
Query: 3098 DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAP-PPLHILDGVLFIGGVQPGYVVSG-SLG 3155
D WH + S+ +LV+D P + G +++GGV PG V +
Sbjct: 1579 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQIN 1638
Query: 3156 SKVPFTGCIGDATING-QVLNLLEPFSNNSVTFG--RCGTTITTGG 3198
S F+GC+ + +NG + + + FS G GT +T G
Sbjct: 1639 SIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEG 1684
Score = 46.0 bits (104), Expect = 0.003
Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 1517 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 1568
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + D W+ VI R +L I D + E LP
Sbjct: 1569 ------LKIRSQEKYNDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 1614
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 1615 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 1660
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 1661 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 1717
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 1718 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 1777
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 1778 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1836
Score = 38.7 bits (86), Expect = 0.39
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN---------TGY 2030
G ++ Q + + R A G ++C AGF++ C C+CN +GY
Sbjct: 67 GSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGY 126
Query: 2031 SVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
V N TG+ CE CL G IG+ P+
Sbjct: 127 CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 156
>X91171-1|CAA62596.1| 1816|Homo sapiens laminin alpha 4 protein.
Length = 1816
Score = 260 bits (636), Expect = 9e-68
Identities = 305/1310 (23%), Positives = 524/1310 (40%), Gaps = 131/1310 (10%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 79 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 133
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIAS 1983
C +A+ C G C+C G C+RCAP ++G L G C C+C S
Sbjct: 134 CPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
Query: 1984 EST----QCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMC 2036
+ CD+ GQCR C + TG +C++CA G++ + C CNC G C
Sbjct: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PC 248
Query: 2037 NA-TGQC--ECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANET 2093
++ TG+C E G CD+C W L + L S + + S A+
Sbjct: 249 DSVTGECLEEGFEPPTG--CDKCV--WDLT-DDLRLAALSIEEGKSGVLSVSSGAAAHRH 303
Query: 2094 MDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAE 2153
++ + A + +L+ NQ L + ++ + + + S ++ L R +
Sbjct: 304 VN-EINATIYLLKTKLSERENQYALRKIQINNAENT-MKSLLSDVEELVEKENQASRKGQ 361
Query: 2154 FAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPK-VDSA 2212
+S I+ A++L E A +R+ +E + L G E PK +
Sbjct: 362 LVQKESMDTINHASQLVEQAHD----MRDKIQEINNKM-----LYYGEEHELSPKEISEK 412
Query: 2213 LTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFE 2272
L A+++ ++I + P Q E V E ++ Q + Q + R F
Sbjct: 413 LVLAQKMLEEIRSRQ--PFFTQRELVDEEADEAYELLS---QAESWQRLHNETRT--LFP 465
Query: 2273 SLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNSVTKLNTAAMGDL 2332
++ + KL D+ E D A + AE++N R + + + + ++
Sbjct: 466 VVLEQLDDYNAKLSDLQEALDQALNHVRDAEDMN---RATAARQRDHEKQQERVREQMEV 522
Query: 2333 IDAAYDIG-NATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEH-LTSE 2390
++ + ++ L H L E
Sbjct: 523 VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQE 582
Query: 2391 ATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXX 2450
A HA L++ A+ L + N Q ++
Sbjct: 583 AIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTD 642
Query: 2451 NVTKLNRILDERVRPARERSSSLLADA----TKAQHAVDQKLLPNLTATEEVLRKIRDHL 2506
+ +D ++ ++ S +LL A KA+ + D+ + L +
Sbjct: 643 RIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALK 702
Query: 2507 SRADDDDNAIQXXXXXXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTL 2566
+R D +Q + N T T V P +W+Q L
Sbjct: 703 TRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRT---TMEVQQATAPMANNLTNWSQNL 759
Query: 2567 PKLADEGQKMTSN-VESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDL 2625
N ++N+ ++ PQ+ TV+ +Q++++L
Sbjct: 760 QHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSAS-----IQRIREL 814
Query: 2626 VEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR--------TKEKDGF 2677
+ Q R+VA++IQV + FD S ++ ++D++ T +S Y + T+ D F
Sbjct: 815 IAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQF 874
Query: 2678 ILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADN-- 2735
ILYLG+ + +YM + I+N V ++G + +D +
Sbjct: 875 ILYLGS-------KNAKKEYMGLAIKNDNLVYVYNLGTKD------VEIPLDSKPVSSWP 921
Query: 2736 RWYQVI-VDRLGRRVKLSIR-ESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVP 2793
++ ++ ++R+G+ K+ + SL + + K+ + G ++ +LD E + YVGGVP
Sbjct: 922 AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVP 981
Query: 2794 SDAKL-QGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQ----RDKLISSQSGPQ 2848
S+ KL ++ P F G +E + + + L+NF + + RDKL +QS
Sbjct: 982 SNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAA 1041
Query: 2849 EYRFDGRGYATMAG--RGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVY 2906
Y FDG GYA + R Q + + RT A NGLI L+ G FF L M++G ++
Sbjct: 1042 SYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLH 1101
Query: 2907 LQVSLGNTEDLIIVGTT---RAYNDGKWHKLD-ARRFLAKCSLTVDNEVLKAESNSPSAD 2962
+ G + + + T ND K+H++ K L VD +K+ N
Sbjct: 1102 VFYDFGFSSGRVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNE-KMK 1160
Query: 2963 IPSLDTMNFGGNNKGILQ-------VP-DRGFDGCMRQISINGVNLDLSENLESIGMAYG 3014
IP D + GG ILQ +P D F GCM+ + +L E E++G+ YG
Sbjct: 1161 IPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYG 1219
Query: 3015 CQFASLVS----FNGTDSYLRFVDVTS--ENPQLTLKFKTAKPNGLLFVYVSRTQTAIMP 3068
C SL+S FNG S++ + S + + F+T +PNGLLF Y S +
Sbjct: 1220 CPEDSLISRRAYFNG-QSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGS------ 1272
Query: 3069 DSISLSLVNGKLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVD 3118
D S+SL NG +++ + ++ + YND H + + + + +L+VD
Sbjct: 1273 DVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1322
Score = 210 bits (512), Expect = 9e-53
Identities = 98/220 (44%), Positives = 125/220 (56%), Gaps = 11/220 (5%)
Query: 1746 SCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
+ E+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G P+ C C CP+P+ + NFA SC +NG+ + C C Y G CE CA GYYG P
Sbjct: 123 RGAPQFCQPCPCPLPHLA-NFAESC-YRKNGA-VRCICNENYAGPNCERCAPGYYGNP-- 177
Query: 1866 TDLHTGDYCKPCNCSGNINPQ-DPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
L G CK C+CSGN +P CD + G C C+ NT G C CAPG+YGDA +
Sbjct: 178 --LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1925 KNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
KNC C C G CDS TG C+ CD+C D
Sbjct: 236 KNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKCVWD 272
Score = 146 bits (353), Expect = 2e-33
Identities = 105/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 1463 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 1518
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S YND WH V R G+L +D V E S+
Sbjct: 1519 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1578
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 1579 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 1637
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 1638 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1693
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 1694 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 1750
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 1751 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1809
Query: 3662 VGVCP 3666
+ CP
Sbjct: 1810 INSCP 1814
Score = 105 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 31/204 (15%)
Query: 387 PPDCSSCAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGY 443
PP C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 444 Y------SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQCQAGYYNYP 492
+P+ C+ C C + + + C + G C C Y+G C +C GYY P
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 493 -----TCKPCNCDTSGTEPSI----CDDVSGQC-ICKAGFGGPRCDQCLSGYYMQVLGRE 542
TCK C+C + ++P++ CD+V+GQC C G +C++C GYY
Sbjct: 178 LLIGSTCKKCDC-SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIA 235
Query: 543 RQCVPCNC--DPTGSTSTSCSADG 564
+ C CNC P S + C +G
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEG 259
Score = 101 bits (243), Expect = 4e-20
Identities = 68/214 (31%), Positives = 91/214 (42%), Gaps = 40/214 (18%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 79 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 348 YGKRWDELDVCQPCQCD-PHFS--TGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
+ + CQPC C PH + +C ++G RC C + P+C CA GY+ P
Sbjct: 121 SIRGAPQF--CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Query: 402 ----NCKPCTCNLNGTEG---EHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE--CKNC 451
CK C C+ N E C G C C N G CE C GYY KNC
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
Query: 452 E-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
CN G CD +TG+C + C++C
Sbjct: 239 AVCNCGGG---PCDSVTGECLEEGFEPPTGCDKC 269
Score = 92.7 bits (220), Expect = 2e-17
Identities = 66/211 (31%), Positives = 90/211 (42%), Gaps = 24/211 (11%)
Query: 435 SCEICEDGYY---SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGYYN 490
+ E C G++ S EC C+CN G+ S C +G C C+ +G C +C GY
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCN--GN-SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 491 YPT------CKPCNCDTS--GTEPSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLG 540
C+PC C C +G +CIC + GP C++C GYY L
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 541 RERQCVPCNC----DPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
C C+C DP G+C NCL N G +C++C+PGYY ++ NC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 596 DVSGSIGSTCDD-NGLCHCKSNFDGAKCDTC 625
V G CD G C + CD C
Sbjct: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 82.6 bits (195), Expect = 2e-14
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 67 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVPGHYAFP-----DCY 1476
C C C PL + N + C +G +C C EN G C+ C PG+Y P C
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
Query: 1477 QCTCNRH---GTTYDVCDQNTAQC-YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCF 1532
+C C+ + ++ CD+ T QC C N G C+ C Y+ C C C
Sbjct: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
Query: 1533 G 1533
G
Sbjct: 245 G 245
Score = 81.0 bits (191), Expect = 7e-14
Identities = 59/223 (26%), Positives = 93/223 (41%), Gaps = 32/223 (14%)
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPG 583
P ++C +G++ + G +CVPC+C+ G+++ G C +C N G C++C G
Sbjct: 62 PAAEKCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 584 YYK-----YPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCDTCREQFYNY 632
Y P C C C + + +C NG C C N+ G C+ C +Y
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 633 P-----ACEECNCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
P C++C+C F C V G+ C G C C P Y+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEV-TGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL 729
C CNC G G C++ +G+C+ + CD+C+
Sbjct: 236 K-NCAVCNC--GG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
Score = 79.8 bits (188), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 1729 RATSVEECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCNGHSD------QCDVNTG 1779
R C C Y G +CE+CA G+Y P C C C+G+SD CD TG
Sbjct: 148 RKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
Score = 79.4 bits (187), Expect = 2e-13
Identities = 61/204 (29%), Positives = 84/204 (41%), Gaps = 33/204 (16%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY-----GFPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 82 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 140
Query: 1395 D-------DNG--MCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGVVGNQLQ 1443
+ NG CIC +N G NC+RC P + + G C C+C+ +
Sbjct: 141 NFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFE 200
Query: 1444 -CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 255
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDD 1521
+ CD C ++L DD
Sbjct: 256 LEEGFEPPTGCDKC---VWDLTDD 276
Score = 77.4 bits (182), Expect = 9e-13
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 28/174 (16%)
Query: 1738 CPRAYRGLSCEQCAEGH----YRLPSGFCVPCQC-----NGHSDQCDVNTGI--CLNCAD 1786
C R G CE+C +G+ R FC PC C ++ C G C+ C +
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNE 159
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
N G +CE C GY+G+ + C C C N CD G NC
Sbjct: 160 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCD-EVTGQ--CRNCLRN 215
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 216 TTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 257
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 1909 ACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG 1967
A C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 63 AAEKCNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 1968 ---LNTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN---Y 2016
C PC C +A+ + C NG +C C + G C++CA G++
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 2017 TKDGCDHCNCNTGYSVGFM---CN-ATGQC-ECLPGVIGEKCDRC 2056
C C+C+ + C+ TGQC CL G KC+RC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + YND
Sbjct: 1486 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYND 1543
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 1544 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 1603
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 1604 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 1659
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 1660 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 1717
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 1718 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 1775
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 1776 LAPSKPFTGCIRHFVIDG 1793
Score = 68.9 bits (161), Expect = 3e-10
Identities = 59/204 (28%), Positives = 78/204 (38%), Gaps = 39/204 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 82 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 131
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + S R G +C+ C N G NC +C P Y YG
Sbjct: 132 CPCPL--------PHLANFAESC---YRKNGAVRCI-CNENYAGPNCERCAPGY---YGN 176
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFD----YP 401
C+ C C DP+ +C+E +G+C C C CA GY+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLC 425
NC C C G C G C
Sbjct: 237 NCAVCNCG-----GGPCDSVTGEC 255
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY-WN 681
+ C F++ + E CD G + GS G C+ G C C Y +
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLD-GS---GYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHVGERQCDQCLDGFYRLQTND 739
P C+ C C L N +C K+G +C+C ++ C++C G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 740 VFGCTECDCDIGGSIDN----NCDKTTGQC-HCHSRVEGRRCDQPIRAHY 784
C +CDC G S N +CD+ TGQC +C G +C++ +Y
Sbjct: 181 GSTCKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 58.4 bits (135), Expect = 5e-07
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 27/147 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C N GP C +C G+ I +C+ C+C ++ DP + +
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNL----IFE 200
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D + E G+C NC NT G C +C P YY + C C C G C+
Sbjct: 201 DCD---EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCD 249
Query: 374 EESGRCECRPEFQPP-DCSSCAYGYFD 399
+G C F+PP C C + D
Sbjct: 250 SVTGEC-LEEGFEPPTGCDKCVWDLTD 275
Score = 57.6 bits (133), Expect = 8e-07
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 24/145 (16%)
Query: 1339 PCLCDFMGSTELECNTFGG--QCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHCPST 1391
PC + + C G +C C N G C C GYYG P C+ C C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN 192
Query: 1392 A-------ICDD-NGMC-ICPKNVEGENCDRCKP-YTFNFDVQRGCDDCNCNPLGVVGNQ 1441
+ CD+ G C C +N G C+RC P Y + + + C CNC G
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG-----GG- 246
Query: 1442 LQCEADSGKCACRENVRGRVCDHCV 1466
C++ +G+C CD CV
Sbjct: 247 -PCDSVTGECLEEGFEPPTGCDKCV 270
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 3041 QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV---VSQREQLDTGLNTYN 3097
Q +++ +T +G++F YVS + D ++L L +G+LV V ++ YN
Sbjct: 1487 QFSIRLRTRSSHGMIF-YVSDQEEN---DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYN 1542
Query: 3098 DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAP-PPLHILDGVLFIGGVQPGYVVSG-SLG 3155
D WH + S+ +LV+D P + G +++GGV PG V +
Sbjct: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQIN 1602
Query: 3156 SKVPFTGCIGDATING-QVLNLLEPFSNNSVTFG--RCGTTITTGG 3198
S F+GC+ + +NG + + + FS G GT +T G
Sbjct: 1603 SIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEG 1648
Score = 46.0 bits (104), Expect = 0.003
Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 1481 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 1532
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + D W+ VI R +L I D + E LP
Sbjct: 1533 ------LKIRSQEKYNDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 1578
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 1579 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 1624
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 1625 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 1681
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 1682 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 1741
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 1742 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
Score = 38.7 bits (86), Expect = 0.39
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN---------TGY 2030
G ++ Q + + R A G ++C AGF++ C C+CN +GY
Sbjct: 38 GSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGY 97
Query: 2031 SVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
V N TG+ CE CL G IG+ P+
Sbjct: 98 CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
>BC066552-1|AAH66552.1| 1816|Homo sapiens LAMA4 protein protein.
Length = 1816
Score = 260 bits (636), Expect = 9e-68
Identities = 305/1310 (23%), Positives = 524/1310 (40%), Gaps = 131/1310 (10%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 79 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 133
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIAS 1983
C +A+ C G C+C G C+RCAP ++G L G C C+C S
Sbjct: 134 CPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
Query: 1984 EST----QCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMC 2036
+ CD+ GQCR C + TG +C++CA G++ + C CNC G C
Sbjct: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PC 248
Query: 2037 NA-TGQC--ECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANET 2093
++ TG+C E G CD+C W L + L S + + S A+
Sbjct: 249 DSVTGECLEEGFEPPTG--CDKCV--WDLT-DDLRLAALSIEEGKSGVLSVSSGAAAHRH 303
Query: 2094 MDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAE 2153
++ + A + +L+ NQ L + ++ + + + S ++ L R +
Sbjct: 304 VN-EINATIYLLKTKLSERENQYALRKIQINNAENT-MKSLLSDVEELVEKENQASRKGQ 361
Query: 2154 FAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPK-VDSA 2212
+S I+ A++L E A +R+ +E + L G E PK +
Sbjct: 362 LVQKESMDTINHASQLVEQAHD----MRDKIQEINNKM-----LYYGEEHELSPKEISEK 412
Query: 2213 LTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFE 2272
L A+++ ++I + P Q E V E ++ Q + Q + R F
Sbjct: 413 LVLAQKMLEEIRSRQ--PFFTQRELVDEEADEAYELLS---QAESWQRLHNETRT--LFP 465
Query: 2273 SLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNSVTKLNTAAMGDL 2332
++ + KL D+ E D A + AE++N R + + + + ++
Sbjct: 466 VVLEQLDDYNAKLSDLQEALDQALNHVRDAEDMN---RATAARQRDHEKQQERVREQMEV 522
Query: 2333 IDAAYDIG-NATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEH-LTSE 2390
++ + ++ L H L E
Sbjct: 523 VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQE 582
Query: 2391 ATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXX 2450
A HA L++ A+ L + N Q ++
Sbjct: 583 AIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTD 642
Query: 2451 NVTKLNRILDERVRPARERSSSLLADA----TKAQHAVDQKLLPNLTATEEVLRKIRDHL 2506
+ +D ++ ++ S +LL A KA+ + D+ + L +
Sbjct: 643 RIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALK 702
Query: 2507 SRADDDDNAIQXXXXXXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTL 2566
+R D +Q + N T T V P +W+Q L
Sbjct: 703 TRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRT---TMEVQQATAPMANNLTNWSQNL 759
Query: 2567 PKLADEGQKMTSN-VESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDL 2625
N ++N+ ++ PQ+ TV+ +Q++++L
Sbjct: 760 QHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSAS-----IQRIREL 814
Query: 2626 VEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR--------TKEKDGF 2677
+ Q R+VA++IQV + FD S ++ ++D++ T +S Y + T+ D F
Sbjct: 815 IAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQF 874
Query: 2678 ILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADN-- 2735
ILYLG+ + +YM + I+N V ++G + +D +
Sbjct: 875 ILYLGS-------KNAKKEYMGLAIKNDNLVYVYNLGTKD------VEIPLDSKPVSSWP 921
Query: 2736 RWYQVI-VDRLGRRVKLSIR-ESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVP 2793
++ ++ ++R+G+ K+ + SL + + K+ + G ++ +LD E + YVGGVP
Sbjct: 922 AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVP 981
Query: 2794 SDAKL-QGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQ----RDKLISSQSGPQ 2848
S+ KL ++ P F G +E + + + L+NF + + RDKL +QS
Sbjct: 982 SNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAA 1041
Query: 2849 EYRFDGRGYATMAG--RGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVY 2906
Y FDG GYA + R Q + + RT A NGLI L+ G FF L M++G ++
Sbjct: 1042 SYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLH 1101
Query: 2907 LQVSLGNTEDLIIVGTT---RAYNDGKWHKLD-ARRFLAKCSLTVDNEVLKAESNSPSAD 2962
+ G + + + T ND K+H++ K L VD +K+ N
Sbjct: 1102 VFYDFGFSSGRVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNE-KMK 1160
Query: 2963 IPSLDTMNFGGNNKGILQ-------VP-DRGFDGCMRQISINGVNLDLSENLESIGMAYG 3014
IP D + GG ILQ +P D F GCM+ + +L E E++G+ YG
Sbjct: 1161 IPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYG 1219
Query: 3015 CQFASLVS----FNGTDSYLRFVDVTS--ENPQLTLKFKTAKPNGLLFVYVSRTQTAIMP 3068
C SL+S FNG S++ + S + + F+T +PNGLLF Y S +
Sbjct: 1220 CPEDSLISRRAYFNG-QSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGS------ 1272
Query: 3069 DSISLSLVNGKLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVD 3118
D S+SL NG +++ + ++ + YND H + + + + +L+VD
Sbjct: 1273 DVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1322
Score = 210 bits (512), Expect = 9e-53
Identities = 98/220 (44%), Positives = 125/220 (56%), Gaps = 11/220 (5%)
Query: 1746 SCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
+ E+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G P+ C C CP+P+ + NFA SC +NG+ + C C Y G CE CA GYYG P
Sbjct: 123 RGAPQFCQPCPCPLPHLA-NFAESC-YRKNGA-VRCICNENYAGPNCERCAPGYYGNP-- 177
Query: 1866 TDLHTGDYCKPCNCSGNINPQ-DPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
L G CK C+CSGN +P CD + G C C+ NT G C CAPG+YGDA +
Sbjct: 178 --LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1925 KNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
KNC C C G CDS TG C+ CD+C D
Sbjct: 236 KNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKCVWD 272
Score = 146 bits (353), Expect = 2e-33
Identities = 105/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 1463 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 1518
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S YND WH V R G+L +D V E S+
Sbjct: 1519 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1578
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 1579 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 1637
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 1638 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1693
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 1694 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 1750
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 1751 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1809
Query: 3662 VGVCP 3666
+ CP
Sbjct: 1810 INSCP 1814
Score = 105 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 31/204 (15%)
Query: 387 PPDCSSCAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGY 443
PP C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 444 Y------SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQCQAGYYNYP 492
+P+ C+ C C + + + C + G C C Y+G C +C GYY P
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 493 -----TCKPCNCDTSGTEPSI----CDDVSGQC-ICKAGFGGPRCDQCLSGYYMQVLGRE 542
TCK C+C + ++P++ CD+V+GQC C G +C++C GYY
Sbjct: 178 LLIGSTCKKCDC-SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIA 235
Query: 543 RQCVPCNC--DPTGSTSTSCSADG 564
+ C CNC P S + C +G
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEG 259
Score = 101 bits (243), Expect = 4e-20
Identities = 68/214 (31%), Positives = 91/214 (42%), Gaps = 40/214 (18%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 79 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 348 YGKRWDELDVCQPCQCD-PHFS--TGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
+ + CQPC C PH + +C ++G RC C + P+C CA GY+ P
Sbjct: 121 SIRGAPQF--CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Query: 402 ----NCKPCTCNLNGTEG---EHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE--CKNC 451
CK C C+ N E C G C C N G CE C GYY KNC
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
Query: 452 E-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
CN G CD +TG+C + C++C
Sbjct: 239 AVCNCGGG---PCDSVTGECLEEGFEPPTGCDKC 269
Score = 92.7 bits (220), Expect = 2e-17
Identities = 66/211 (31%), Positives = 90/211 (42%), Gaps = 24/211 (11%)
Query: 435 SCEICEDGYY---SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGYYN 490
+ E C G++ S EC C+CN G+ S C +G C C+ +G C +C GY
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCN--GN-SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 491 YPT------CKPCNCDTS--GTEPSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLG 540
C+PC C C +G +CIC + GP C++C GYY L
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 541 RERQCVPCNC----DPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
C C+C DP G+C NCL N G +C++C+PGYY ++ NC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 596 DVSGSIGSTCDD-NGLCHCKSNFDGAKCDTC 625
V G CD G C + CD C
Sbjct: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 82.6 bits (195), Expect = 2e-14
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 67 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVPGHYAFP-----DCY 1476
C C C PL + N + C +G +C C EN G C+ C PG+Y P C
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
Query: 1477 QCTCNRH---GTTYDVCDQNTAQC-YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCF 1532
+C C+ + ++ CD+ T QC C N G C+ C Y+ C C C
Sbjct: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
Query: 1533 G 1533
G
Sbjct: 245 G 245
Score = 81.0 bits (191), Expect = 7e-14
Identities = 59/223 (26%), Positives = 93/223 (41%), Gaps = 32/223 (14%)
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPG 583
P ++C +G++ + G +CVPC+C+ G+++ G C +C N G C++C G
Sbjct: 62 PAAEKCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 584 YYK-----YPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCDTCREQFYNY 632
Y P C C C + + +C NG C C N+ G C+ C +Y
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 633 P-----ACEECNCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
P C++C+C F C V G+ C G C C P Y+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEV-TGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL 729
C CNC G G C++ +G+C+ + CD+C+
Sbjct: 236 K-NCAVCNC--GG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
Score = 79.8 bits (188), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 1729 RATSVEECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCNGHSD------QCDVNTG 1779
R C C Y G +CE+CA G+Y P C C C+G+SD CD TG
Sbjct: 148 RKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
Score = 79.4 bits (187), Expect = 2e-13
Identities = 61/204 (29%), Positives = 84/204 (41%), Gaps = 33/204 (16%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY-----GFPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 82 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 140
Query: 1395 D-------DNG--MCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGVVGNQLQ 1443
+ NG CIC +N G NC+RC P + + G C C+C+ +
Sbjct: 141 NFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFE 200
Query: 1444 -CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 255
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDD 1521
+ CD C ++L DD
Sbjct: 256 LEEGFEPPTGCDKC---VWDLTDD 276
Score = 77.4 bits (182), Expect = 9e-13
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 28/174 (16%)
Query: 1738 CPRAYRGLSCEQCAEGH----YRLPSGFCVPCQC-----NGHSDQCDVNTGI--CLNCAD 1786
C R G CE+C +G+ R FC PC C ++ C G C+ C +
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNE 159
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
N G +CE C GY+G+ + C C C N CD G NC
Sbjct: 160 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCD-EVTGQ--CRNCLRN 215
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 216 TTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 257
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 1909 ACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG 1967
A C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 63 AAEKCNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 1968 ---LNTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN---Y 2016
C PC C +A+ + C NG +C C + G C++CA G++
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 2017 TKDGCDHCNCNTGYSVGFM---CN-ATGQC-ECLPGVIGEKCDRC 2056
C C+C+ + C+ TGQC CL G KC+RC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + YND
Sbjct: 1486 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYND 1543
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 1544 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 1603
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 1604 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 1659
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 1660 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 1717
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 1718 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 1775
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 1776 LAPSKPFTGCIRHFVIDG 1793
Score = 68.9 bits (161), Expect = 3e-10
Identities = 59/204 (28%), Positives = 78/204 (38%), Gaps = 39/204 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 82 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 131
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + S R G +C+ C N G NC +C P Y YG
Sbjct: 132 CPCPL--------PHLANFAESC---YRKNGAVRCI-CNENYAGPNCERCAPGY---YGN 176
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFD----YP 401
C+ C C DP+ +C+E +G+C C C CA GY+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLC 425
NC C C G C G C
Sbjct: 237 NCAVCNCG-----GGPCDSVTGEC 255
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY-WN 681
+ C F++ + E CD G + GS G C+ G C C Y +
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLD-GS---GYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHVGERQCDQCLDGFYRLQTND 739
P C+ C C L N +C K+G +C+C ++ C++C G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 740 VFGCTECDCDIGGSIDN----NCDKTTGQC-HCHSRVEGRRCDQPIRAHY 784
C +CDC G S N +CD+ TGQC +C G +C++ +Y
Sbjct: 181 GSTCKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 58.4 bits (135), Expect = 5e-07
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 27/147 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C N GP C +C G+ I +C+ C+C ++ DP + +
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNL----IFE 200
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D + E G+C NC NT G C +C P YY + C C C G C+
Sbjct: 201 DCD---EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCD 249
Query: 374 EESGRCECRPEFQPP-DCSSCAYGYFD 399
+G C F+PP C C + D
Sbjct: 250 SVTGEC-LEEGFEPPTGCDKCVWDLTD 275
Score = 57.6 bits (133), Expect = 8e-07
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 24/145 (16%)
Query: 1339 PCLCDFMGSTELECNTFGG--QCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHCPST 1391
PC + + C G +C C N G C C GYYG P C+ C C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN 192
Query: 1392 A-------ICDD-NGMC-ICPKNVEGENCDRCKP-YTFNFDVQRGCDDCNCNPLGVVGNQ 1441
+ CD+ G C C +N G C+RC P Y + + + C CNC G
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG-----GG- 246
Query: 1442 LQCEADSGKCACRENVRGRVCDHCV 1466
C++ +G+C CD CV
Sbjct: 247 -PCDSVTGECLEEGFEPPTGCDKCV 270
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 3041 QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV---VSQREQLDTGLNTYN 3097
Q +++ +T +G++F YVS + D ++L L +G+LV V ++ YN
Sbjct: 1487 QFSIRLRTRSSHGMIF-YVSDQEEN---DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYN 1542
Query: 3098 DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAP-PPLHILDGVLFIGGVQPGYVVSG-SLG 3155
D WH + S+ +LV+D P + G +++GGV PG V +
Sbjct: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQIN 1602
Query: 3156 SKVPFTGCIGDATING-QVLNLLEPFSNNSVTFG--RCGTTITTGG 3198
S F+GC+ + +NG + + + FS G GT +T G
Sbjct: 1603 SIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEG 1648
Score = 46.0 bits (104), Expect = 0.003
Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 1481 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 1532
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + D W+ VI R +L I D + E LP
Sbjct: 1533 ------LKIRSQEKYNDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 1578
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 1579 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 1624
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 1625 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 1681
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 1682 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 1741
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 1742 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
Score = 38.7 bits (86), Expect = 0.39
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN---------TGY 2030
G ++ Q + + R A G ++C AGF++ C C+CN +GY
Sbjct: 38 GSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGY 97
Query: 2031 SVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
V N TG+ CE CL G IG+ P+
Sbjct: 98 CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
>S78569-1|AAB34635.1| 1816|Homo sapiens laminin alpha 4 chain protein.
Length = 1816
Score = 258 bits (632), Expect = 3e-67
Identities = 304/1310 (23%), Positives = 523/1310 (39%), Gaps = 131/1310 (10%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 79 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 133
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIAS 1983
C +A+ C G C+C G C+RCAP ++G G C C+C S
Sbjct: 134 CPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPFLIGSTCKKCDCSGNS 193
Query: 1984 EST----QCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMC 2036
+ CD+ GQCR C + TG +C++CA G++ + C CNC G C
Sbjct: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PC 248
Query: 2037 NA-TGQC--ECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANET 2093
++ TG+C E G CD+C W L + L S + + S A+
Sbjct: 249 DSVTGECLEEGFEPPTG--CDKCV--WDLT-DDLRLAALSIEEGKSGVLSVSSGAAAHRH 303
Query: 2094 MDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAE 2153
++ + A + +L+ NQ L + ++ + + + S ++ L R +
Sbjct: 304 VN-EINATIYLLKTKLSERENQYALRKIQINNAENT-MKSLLSDVEELVEKENQASRKGQ 361
Query: 2154 FAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADLATGLELSQQPK-VDSA 2212
+S I+ A++L E A +R+ +E + L G E PK +
Sbjct: 362 LVQKESMDTINHASQLVEQAHD----MRDKIQEINNKM-----LYYGEEHELSPKEISEK 412
Query: 2213 LTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFE 2272
L A+++ ++I + P Q E V E ++ Q + Q + R F
Sbjct: 413 LVLAQKMLEEIRSRQ--PFFTQRELVDEEADEAYELLS---QAESWQRLHNETRT--LFP 465
Query: 2273 SLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGNKVNSVTKLNTAAMGDL 2332
++ + KL D+ E D A + AE++N R + + + + ++
Sbjct: 466 VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMN---RATAARQRDHEKQQERVREQMEV 522
Query: 2333 IDAAYDIG-NATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEH-LTSE 2390
++ + ++ L H L E
Sbjct: 523 VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQE 582
Query: 2391 ATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXX 2450
A HA L++ A+ L + N Q ++
Sbjct: 583 AIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTD 642
Query: 2451 NVTKLNRILDERVRPARERSSSLLADA----TKAQHAVDQKLLPNLTATEEVLRKIRDHL 2506
+ +D ++ ++ S +LL A KA+ + D+ + L +
Sbjct: 643 RIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALK 702
Query: 2507 SRADDDDNAIQXXXXXXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTL 2566
+R D +Q + N T T V P +W+Q L
Sbjct: 703 TRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRT---TMEVQQATAPMANNLTNWSQNL 759
Query: 2567 PKLADEGQKMTSN-VESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDL 2625
N ++N+ ++ PQ+ TV+ +Q++++L
Sbjct: 760 QHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSAS-----IQRIREL 814
Query: 2626 VEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR--------TKEKDGF 2677
+ Q R+VA++IQV + FD S ++ ++D++ T +S Y + T+ D F
Sbjct: 815 IAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQF 874
Query: 2678 ILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADN-- 2735
ILYLG+ + +YM + I+N V ++G + +D +
Sbjct: 875 ILYLGS-------KNAKKEYMGLAIKNDNLVYVYNLGTKD------VEIPLDSKPVSSWP 921
Query: 2736 RWYQVI-VDRLGRRVKLSIR-ESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVP 2793
++ ++ ++R+G+ K+ + SL + + K+ + G ++ +LD E + YVGGVP
Sbjct: 922 AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVP 981
Query: 2794 SDAKL-QGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQ----RDKLISSQSGPQ 2848
S+ KL ++ P F G +E + + + L+NF + + RDKL +QS
Sbjct: 982 SNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAA 1041
Query: 2849 EYRFDGRGYATMAG--RGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVY 2906
Y FDG GYA + R Q + + RT A NGLI L+ G FF L M++G ++
Sbjct: 1042 SYFFDGSGYAVVRDIPRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLH 1101
Query: 2907 LQVSLGNTEDLIIVGTT---RAYNDGKWHKLD-ARRFLAKCSLTVDNEVLKAESNSPSAD 2962
+ G + + + T ND K+H++ K L VD +K+ N
Sbjct: 1102 VFYDFGFSSGRVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNE-KMK 1160
Query: 2963 IPSLDTMNFGGNNKGILQ-------VP-DRGFDGCMRQISINGVNLDLSENLESIGMAYG 3014
IP D + GG ILQ +P D F GCM+ + +L E E++G+ YG
Sbjct: 1161 IPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYG 1219
Query: 3015 CQFASLVS----FNGTDSYLRFVDVTS--ENPQLTLKFKTAKPNGLLFVYVSRTQTAIMP 3068
C SL+S FNG S++ + S + + F+T +PNGLLF Y S +
Sbjct: 1220 CPEDSLISRRAYFNG-QSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGS------ 1272
Query: 3069 DSISLSLVNGKLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVD 3118
D S+SL NG +++ + ++ + YND H + + + + +L+VD
Sbjct: 1273 DVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1322
Score = 206 bits (503), Expect = 1e-51
Identities = 96/220 (43%), Positives = 123/220 (55%), Gaps = 11/220 (5%)
Query: 1746 SCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
+ E+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G P+ C C CP+P+ + NF SC +NG+ + C C Y G CE CA GYYG P
Sbjct: 123 RGAPQFCQPCPCPLPHLA-NFPESC-YRKNGA-VRCICNENYAGPNCERCAPGYYGNP-- 177
Query: 1866 TDLHTGDYCKPCNCSGNINPQ-DPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
G CK C+CSGN +P CD + G C C+ NT G C CAPG+YGDA +
Sbjct: 178 --FLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1925 KNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
KNC C C G CDS TG C+ CD+C D
Sbjct: 236 KNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKCVWD 272
Score = 146 bits (353), Expect = 2e-33
Identities = 105/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 1463 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 1518
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S YND WH V R G+L +D V E S+
Sbjct: 1519 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1578
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 1579 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 1637
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 1638 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1693
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 1694 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 1750
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 1751 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1809
Query: 3662 VGVCP 3666
+ CP
Sbjct: 1810 INSCP 1814
Score = 105 bits (251), Expect = 4e-21
Identities = 67/204 (32%), Positives = 93/204 (45%), Gaps = 31/204 (15%)
Query: 387 PPDCSSCAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGY 443
PP C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 444 Y------SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQCQAGYYNYP 492
+P+ C+ C C + + C + G C C Y+G C +C GYY P
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 493 -----TCKPCNCDTSGTEPSI----CDDVSGQC-ICKAGFGGPRCDQCLSGYYMQVLGRE 542
TCK C+C + ++P++ CD+V+GQC C G +C++C GYY
Sbjct: 178 FLIGSTCKKCDC-SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIA 235
Query: 543 RQCVPCNC--DPTGSTSTSCSADG 564
+ C CNC P S + C +G
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEG 259
Score = 101 bits (243), Expect = 4e-20
Identities = 68/214 (31%), Positives = 91/214 (42%), Gaps = 40/214 (18%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 79 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 348 YGKRWDELDVCQPCQCD-PHFST--GNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
+ + CQPC C PH + +C ++G RC C + P+C CA GY+ P
Sbjct: 121 SIRGAPQF--CQPCPCPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPF 178
Query: 402 ----NCKPCTCNLNGTEG---EHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE--CKNC 451
CK C C+ N E C G C C N G CE C GYY KNC
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
Query: 452 E-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
CN G CD +TG+C + C++C
Sbjct: 239 AVCNCGGG---PCDSVTGECLEEGFEPPTGCDKC 269
Score = 92.7 bits (220), Expect = 2e-17
Identities = 59/181 (32%), Positives = 86/181 (47%), Gaps = 26/181 (14%)
Query: 483 QCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYMQ-V 538
+C AG+++ + C PC+C+ + E C D SG C+ C+ G C++CL GY +
Sbjct: 66 KCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 539 LGRERQCVPCNCD--PTGSTSTSCSADG---KCNCLTNFGGAQCDQCSPGYYKYPDCL-- 591
G + C PC C + SC +C C N+ G C++C+PGYY P +
Sbjct: 123 RGAPQFCQPCPCPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPFLIGS 182
Query: 592 SC-NCDVSGS-----IGSTCDD-NGLC-HCKSNFDGAKCDTCREQFYN----YPACEECN 639
+C CD SG+ I CD+ G C +C N G KC+ C +Y C CN
Sbjct: 183 TCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCN 242
Query: 640 C 640
C
Sbjct: 243 C 243
Score = 81.8 bits (193), Expect = 4e-14
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 67 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVPGHYAFP-----DCY 1476
C C C PL + N + C +G +C C EN G C+ C PG+Y P C
Sbjct: 127 QFCQPCPC-PLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPFLIGSTCK 185
Query: 1477 QCTCNRH---GTTYDVCDQNTAQC-YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCF 1532
+C C+ + ++ CD+ T QC C N G C+ C Y+ C C C
Sbjct: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
Query: 1533 G 1533
G
Sbjct: 245 G 245
Score = 81.0 bits (191), Expect = 7e-14
Identities = 62/204 (30%), Positives = 84/204 (41%), Gaps = 33/204 (16%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY-----GFPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 82 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 140
Query: 1395 D-------DNG--MCICPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGNQLQ 1443
+ NG CIC +N G NC+RC P Y F + C C+C+ +
Sbjct: 141 NFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPFLIGSTCKKCDCSGNSDPNLIFE 200
Query: 1444 -CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 255
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDD 1521
+ CD C ++L DD
Sbjct: 256 LEEGFEPPTGCDKC---VWDLTDD 276
Score = 80.2 bits (189), Expect = 1e-13
Identities = 59/223 (26%), Positives = 93/223 (41%), Gaps = 32/223 (14%)
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPG 583
P ++C +G++ + G +CVPC+C+ G+++ G C +C N G C++C G
Sbjct: 62 PAAEKCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 584 YYK-----YPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCDTCREQFYNY 632
Y P C C C + + +C NG C C N+ G C+ C +Y
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 633 P-----ACEECNCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
P C++C+C F C V G+ C G C C P Y+
Sbjct: 177 PFLIGSTCKKCDCSGNSDPNLIFEDCDEV-TGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL 729
C CNC G G C++ +G+C+ + CD+C+
Sbjct: 236 K-NCAVCNCG--G-----GPCDSVTGECLEEGFEPPTGCDKCV 270
Score = 79.8 bits (188), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 1729 RATSVEECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCNGHSD------QCDVNTG 1779
R C C Y G +CE+CA G+Y P C C C+G+SD CD TG
Sbjct: 148 RKNGAVRCICNENYAGPNCERCAPGYYGNPFLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
Score = 76.6 bits (180), Expect = 2e-12
Identities = 57/175 (32%), Positives = 72/175 (41%), Gaps = 30/175 (17%)
Query: 1738 CPRAYRGLSCEQCAEGH----YRLPSGFCVPCQC-----NGHSDQCDVNTGI--CLNCAD 1786
C R G CE+C +G+ R FC PC C + C G C+ C +
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFPESCYRKNGAVRCI-CNE 159
Query: 1787 NTIGDHCEFCMSGYHGDA-TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
N G +CE C GY+G+ +G+ C C C N CD G NC
Sbjct: 160 NYAGPNCERCAPGYYGNPFLIGS--TCKKCDCSGNSDPNLIFEDCD-EVTGQ--CRNCLR 214
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 215 NTTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 257
Score = 70.5 bits (165), Expect = 1e-10
Identities = 58/204 (28%), Positives = 79/204 (38%), Gaps = 39/204 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 82 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 131
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C PE ++ G +C+ C N G NC +C P Y YG
Sbjct: 132 CPC--PLPHLANFPESCYRK---------NGAVRCI-CNENYAGPNCERCAPGY---YGN 176
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFD----YP 401
+ C+ C C DP+ +C+E +G+C C C CA GY+
Sbjct: 177 PFLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLC 425
NC C C G C G C
Sbjct: 237 NCAVCNCG-----GGPCDSVTGEC 255
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + YND
Sbjct: 1486 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYND 1543
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 1544 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 1603
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 1604 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 1659
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 1660 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 1717
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 1718 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 1775
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 1776 LAPSKPFTGCIRHFVIDG 1793
Score = 68.5 bits (160), Expect = 4e-10
Identities = 48/165 (29%), Positives = 69/165 (41%), Gaps = 20/165 (12%)
Query: 1909 ACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG 1967
A C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 63 AAEKCNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 1968 ---LNTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN---Y 2016
C PC C +A+ C NG +C C + G C++CA G++
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPFL 179
Query: 2017 TKDGCDHCNCNTGYSVGFM---CN-ATGQC-ECLPGVIGEKCDRC 2056
C C+C+ + C+ TGQC CL G KC+RC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 62.5 bits (145), Expect = 3e-08
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY-WN 681
+ C F++ + E CD G + GS G C+ G C C Y +
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLD-GS---GYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHVGERQCDQCLDGFYRLQTND 739
P C+ C C L N +C K+G +C+C ++ C++C G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPFLI 180
Query: 740 VFGCTECDCDIGGSIDN----NCDKTTGQC-HCHSRVEGRRCDQPIRAHY 784
C +CDC G S N +CD+ TGQC +C G +C++ +Y
Sbjct: 181 GSTCKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 59.7 bits (138), Expect = 2e-07
Identities = 41/147 (27%), Positives = 59/147 (40%), Gaps = 27/147 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C N GP C +C G+ + I +C+ C+C ++ DP + +
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPFLIGS-----TCKKCDCSGNS-----DPNL----IFE 200
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D + E G+C NC NT G C +C P YY + C C C G C+
Sbjct: 201 DCD---EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCD 249
Query: 374 EESGRCECRPEFQPP-DCSSCAYGYFD 399
+G C F+PP C C + D
Sbjct: 250 SVTGEC-LEEGFEPPTGCDKCVWDLTD 275
Score = 57.6 bits (133), Expect = 8e-07
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 24/145 (16%)
Query: 1339 PCLCDFMGSTELECNTFGG--QCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHCPST 1391
PC + + C G +C C N G C C GYYG P C+ C C
Sbjct: 133 PCPLPHLANFPESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPFLIGSTCKKCDCSGN 192
Query: 1392 A-------ICDD-NGMC-ICPKNVEGENCDRCKP-YTFNFDVQRGCDDCNCNPLGVVGNQ 1441
+ CD+ G C C +N G C+RC P Y + + + C CNC G
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG-----GG- 246
Query: 1442 LQCEADSGKCACRENVRGRVCDHCV 1466
C++ +G+C CD CV
Sbjct: 247 -PCDSVTGECLEEGFEPPTGCDKCV 270
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 3041 QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV---VSQREQLDTGLNTYN 3097
Q +++ +T +G++F YVS + D ++L L +G+LV V ++ YN
Sbjct: 1487 QFSIRLRTRSSHGMIF-YVSDQEEN---DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYN 1542
Query: 3098 DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAP-PPLHILDGVLFIGGVQPGYVVSG-SLG 3155
D WH + S+ +LV+D P + G +++GGV PG V +
Sbjct: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQIN 1602
Query: 3156 SKVPFTGCIGDATING-QVLNLLEPFSNNSVTFG--RCGTTITTGG 3198
S F+GC+ + +NG + + + FS G GT +T G
Sbjct: 1603 SIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEG 1648
Score = 46.0 bits (104), Expect = 0.003
Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 1481 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 1532
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + D W+ VI R +L I D + E LP
Sbjct: 1533 ------LKIRSQEKYNDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 1578
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 1579 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 1624
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 1625 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 1681
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 1682 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 1741
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 1742 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
Score = 38.7 bits (86), Expect = 0.39
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN---------TGY 2030
G ++ Q + + R A G ++C AGF++ C C+CN +GY
Sbjct: 38 GSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGY 97
Query: 2031 SVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
V N TG+ CE CL G IG+ P+
Sbjct: 98 CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
>U75586-1|AAD09221.1| 604|Homo sapiens netrin-1 protein.
Length = 604
Score = 246 bits (603), Expect = 9e-64
Identities = 130/373 (34%), Positives = 199/373 (53%), Gaps = 31/373 (8%)
Query: 34 CDICDANNEAKKHPPEYAVD----DRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVF 89
C +C+A++ K HPP + D T WQS + +N V LT+ LG++F V YV
Sbjct: 91 CHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQ-FPHN-VTLTLSLGKKFEVTYVS 148
Query: 90 VKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITK--DDSVICS 147
++ SPRPE + KS DYG+T+ P+Q++S C + + + PITK + +C+
Sbjct: 149 LQFC-SPRPESMAIYKSMDYGRTWVPFQFYSTQ---CRKMYNRPHRAPITKQNEQEAVCT 204
Query: 148 TEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSV 207
++ + PL G I S L+ RPS++ + NS VLQ+W AT++R+ R H
Sbjct: 205 DSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----HTFGD 259
Query: 208 ARQDPTVTRR--YFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQC 265
+D + R YFY++ D+ +GGRC CNGHA C + LVC C+HNT GP+C
Sbjct: 260 ENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCV----RDRTDSLVCDCRHNTAGPEC 315
Query: 266 NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
++C + W+ + + C CNC+ H C ++ E+ + ++GR + GG C
Sbjct: 316 DRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYK------LSGR-KSGGVC 368
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPE 384
LNC+HNT G +C+ C+ YYR GK C+ C C P + G C + +G+C C+
Sbjct: 369 LNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDG 428
Query: 385 FQPPDCSSCAYGY 397
C+ CA GY
Sbjct: 429 VTGITCNRCAKGY 441
Score = 87.0 bits (206), Expect = 1e-15
Identities = 63/227 (27%), Positives = 93/227 (40%), Gaps = 47/227 (20%)
Query: 354 ELDVCQPCQCDPHFSTGNCEE-ESGRCECRPEFQPPDCSSCAYGYFDYP----------N 402
+L V C+C+ H + + +S C+CR P+C C ++D P
Sbjct: 278 DLQVGGRCKCNGHAARCVRDRTDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANE 337
Query: 403 CKPCTCNLNGTEGEHCTP--------TDGLC-PCKYNYAGKSCEICEDGYYSP------- 446
C C CNL+ + G+C C++N AG+ C C++GYY
Sbjct: 338 CVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITH 397
Query: 447 --ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY----------YNYPTC 494
CK C+C+ VG+ C++ TG C CK +G TCN+C GY P
Sbjct: 398 RKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVA 457
Query: 495 KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSGYYMQV 538
P +S EP CD CKA G + + C Y +Q+
Sbjct: 458 PPTTAASSVEEPEDCDS-----YCKASKGKLKINMKKYCKKDYAVQI 499
Score = 76.6 bits (180), Expect = 2e-12
Identities = 50/156 (32%), Positives = 64/156 (41%), Gaps = 32/156 (20%)
Query: 1727 VRRATSVEECQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT 1778
VR T C C G C++C HY P + CV C CN H+ +C N
Sbjct: 295 VRDRTDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNM 354
Query: 1779 -----------GICLNCADNTIGDHCEFCMSGYHGDATVGTP----RDCLICACPMPYPS 1823
G+CLNC NT G HC +C GY+ D +G P + C C C +P
Sbjct: 355 ELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRD--MGKPITHRKACKACDC---HPV 409
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGY 1859
+C N + C C+ G G C CA GY
Sbjct: 410 GAAGKTC----NQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 76.2 bits (179), Expect = 2e-12
Identities = 54/168 (32%), Positives = 68/168 (40%), Gaps = 25/168 (14%)
Query: 1396 DNGMCICPKNVEGENCDRCKPYTFNFDVQRG-------CDDCNCN------PLGVVGNQL 1442
D+ +C C N G CDRCKP+ ++ QR C CNCN + +L
Sbjct: 300 DSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKL 359
Query: 1443 QCEADSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYDVCDQN 1493
G C CR N GR C +C G+Y C C C+ G C+Q
Sbjct: 360 SGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQT 419
Query: 1494 TAQCYCKTNVRGQACDTCKEEYFNLQDDNPDG-CTKCFCFGKTTRCSS 1540
T QC CK V G C+ C + Y Q +P C K TT SS
Sbjct: 420 TGQCPCKDGVTGITCNRCAKGY--QQSRSPIAPCIKIPVAPPTTAASS 465
Score = 74.1 bits (174), Expect = 9e-12
Identities = 49/162 (30%), Positives = 67/162 (41%), Gaps = 14/162 (8%)
Query: 1765 CQCNGHSDQC--DVNTGICLNCADNTIGDHCEFCMSGYHGD-----ATVGTPRDCLICAC 1817
C+CNGH+ +C D + +C NT G C+ C +H D AT +C+ C C
Sbjct: 285 CKCNGHAARCVRDRTDSLVCDCRHNTAGPECDRCKP-FHYDRPWQRATAREANECVACNC 343
Query: 1818 PMPYPSNNFALSC-DLSENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCK 1875
+ F + LS S C NC+ G C YC GYY H CK
Sbjct: 344 NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHR-KACK 402
Query: 1876 PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
C+C + +C+ G C C + G CN CA G+
Sbjct: 403 ACDCH-PVGAAGK-TCNQTTGQC-PCKDGVTGITCNRCAKGY 441
Score = 68.9 bits (161), Expect = 3e-10
Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 19/136 (13%)
Query: 660 LCQCKDRVQGRICNDCKPLYWN-------LQEYNPFGCEQCNCNLAG-----TLNSLGAC 707
+C C+ G C+ CKP +++ +E N C CNCNL +
Sbjct: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANE--CVACNCNLHARRCRFNMELYKLS 360
Query: 708 NTKSGQ-CV-CKQHVGERQCDQCLDGFYRLQTNDVF---GCTECDCDIGGSIDNNCDKTT 762
KSG C+ C+ + R C C +G+YR + C CDC G+ C++TT
Sbjct: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT 420
Query: 763 GQCHCHSRVEGRRCDQ 778
GQC C V G C++
Sbjct: 421 GQCPCKDGVTGITCNR 436
Score = 64.1 bits (149), Expect = 9e-09
Identities = 40/134 (29%), Positives = 54/134 (40%), Gaps = 24/134 (17%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGLG---CTPCNCGIASESTQCDDD-------- 1991
C CR G +CDRC P H W T C CNC + + + + +
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWNYT------KDGCDHCNCNTGYSVGFMCN-ATGQC 2042
G C C G+ C C G++ + C C+C+ + G CN TGQC
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
Query: 2043 ECLPGVIGEKCDRC 2056
C GV G C+RC
Sbjct: 424 PCKDGVTGITCNRC 437
Score = 62.5 bits (145), Expect = 3e-08
Identities = 49/171 (28%), Positives = 69/171 (40%), Gaps = 29/171 (16%)
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFY------G 1919
+DL G CK C+G+ DS+ DC +NTAG C+ C P Y
Sbjct: 277 SDLQVGGRCK---CNGHAARCVRDRTDSLVCDCR---HNTAGPECDRCKPFHYDRPWQRA 330
Query: 1920 DAIFSKNCTACICD------EFGMA----DCDSTTGTCV-CRPGVIGEKCDRCAPDHWG- 1967
A + C AC C+ F M + G C+ CR G C C ++
Sbjct: 331 TAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRD 390
Query: 1968 ----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
+ C C+C + + C+ GQC C GVTG C++CA G+
Sbjct: 391 MGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 62.5 bits (145), Expect = 3e-08
Identities = 40/159 (25%), Positives = 64/159 (40%), Gaps = 27/159 (16%)
Query: 451 CECN--TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP----------TCKPCN 498
C+CN V D L C C+ +G C++C+ +Y+ P C CN
Sbjct: 285 CKCNGHAARCVRDRTDSLV--CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACN 342
Query: 499 CDTSGTEPSICDDV--------SGQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCV 546
C+ ++ G C+ C+ G C C GYY + + + C
Sbjct: 343 CNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACK 402
Query: 547 PCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGY 584
C+C P G+ +C+ G+C C G C++C+ GY
Sbjct: 403 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 62.1 bits (144), Expect = 4e-08
Identities = 46/161 (28%), Positives = 67/161 (41%), Gaps = 33/161 (20%)
Query: 548 CNCDPTGSTSTSCSADGK-CNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNCD 596
C C+ + D C+C N G +CD+C P +Y P +C++CNC+
Sbjct: 285 CKCNGHAARCVRDRTDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 597 VSGSIG---------STCDDNGLC-HCKSNFDGAKCDTCREQFY--------NYPACEEC 638
+ S G+C +C+ N G C C+E +Y + AC+ C
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
Query: 639 NCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
+C P G A+ C G+ C CKD V G CN C Y
Sbjct: 405 DCHPVG--AAGKTCNQT-TGQ-CPCKDGVTGITCNRCAKGY 441
Score = 61.3 bits (142), Expect = 6e-08
Identities = 40/145 (27%), Positives = 57/145 (39%), Gaps = 22/145 (15%)
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG----- 651
D+ +C C+ N G +CD C+ Y+ P C CNC+ F
Sbjct: 300 DSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKL 359
Query: 652 CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF----GCEQCNCNLAGTLNSLGAC 707
G G C+ GR C+ CK Y+ P C+ C+C+ G C
Sbjct: 360 SGRKSGGVCLNCRHNTAGRHCHYCKEGYYR-DMGKPITHRKACKACDCHPVGAAGK--TC 416
Query: 708 NTKSGQCVCKQHVGERQCDQCLDGF 732
N +GQC CK V C++C G+
Sbjct: 417 NQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 50.0 bits (114), Expect = 2e-04
Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 22/114 (19%)
Query: 1422 DVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP-------- 1473
D+Q G C CN G ++ DS C CR N G CD C P HY P
Sbjct: 278 DLQVG-GRCKCN--GHAARCVRDRTDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATARE 334
Query: 1474 --DCYQCTCNRHG-------TTYDVCDQNT-AQCY-CKTNVRGQACDTCKEEYF 1516
+C C CN H Y + + + C C+ N G+ C CKE Y+
Sbjct: 335 ANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYY 388
Score = 50.0 bits (114), Expect = 2e-04
Identities = 40/124 (32%), Positives = 53/124 (42%), Gaps = 16/124 (12%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQC-PCKP 1363
++C + +Y P + REA + N AR C + M +L GG C C+
Sbjct: 316 DRCKPF-HYDRPWQRATAREANECVACNCNLHARRCRFN-MELYKLSGRKSGGVCLNCRH 373
Query: 1364 NVIGRTCSACRTGYY---GFP-----NCRPCHC-PSTA---ICDD-NGMCICPKNVEGEN 1410
N GR C C+ GYY G P C+ C C P A C+ G C C V G
Sbjct: 374 NTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGIT 433
Query: 1411 CDRC 1414
C+RC
Sbjct: 434 CNRC 437
Score = 46.4 bits (105), Expect = 0.002
Identities = 18/45 (40%), Positives = 23/45 (51%)
Query: 1333 YNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGY 1377
+ + C C +G+ CN GQCPCK V G TC+ C GY
Sbjct: 397 HRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
>D37766-1|BAA22263.1| 1172|Homo sapiens Laminin-5 beta3 chain
protein.
Length = 1172
Score = 245 bits (600), Expect = 2e-63
Identities = 155/518 (29%), Positives = 235/518 (45%), Gaps = 55/518 (10%)
Query: 58 WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQ 117
WWQS N V+L +DL + F + V ++ P P ++E+S+D+GKT++ +Q
Sbjct: 94 WWQSQN-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQ 147
Query: 118 YFSDSPQDCERYFGK-ESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYF 176
Y + DC F + +P + D S L G++ ++L+ D S
Sbjct: 148 YLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLM-DLVSGIPAT 203
Query: 177 NSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGH 236
S +QE TN+R+ R L + P+ +Y++ + + G C C+GH
Sbjct: 204 QSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGH 255
Query: 237 ADTCEP-----ADPAGNLNIL-VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
AD C P A P+ + + VC CQHNT GP C +C + + WR ++ D C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR 315
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C+ H+ C +DP + G Y GG C NC+ +TEG NC +C+ Y+R
Sbjct: 316 CDCNGHSETCHFDPAVFAAS-----QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 351 RWDELDVCQPCQCDPHFST--GNCEEESGRCECRPEFQPPDCSSCAYGY--FDYPN---C 403
+ C C+CDP + C+ +G+C C+ Q C C G+ Y N C
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 404 KPCTCNLNGTEGE-HCTPTDGLCPCKYNYAGKSCEICEDGYY----SPECKNCECNTVGS 458
C CN+ G+ + C G C C N G C+ C ++ C+ C C+ S
Sbjct: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
Query: 459 VSYVCDKLTGDCTCKSKYSGRTCN-----QC-QAGYYNYPT-CKPCNCDTSGTEPSICDD 511
+ C+ + G C+ QC Y + T C+ C+CD GTE CD
Sbjct: 489 PQPTVQPVHRAVPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN 549
SG+C+C+ G GPRCDQC GY R CV C+
Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGY----CNRYPVCVACH 582
Score = 152 bits (369), Expect = 2e-35
Identities = 101/341 (29%), Positives = 146/341 (42%), Gaps = 37/341 (10%)
Query: 1765 CQCNGHSDQCDVNTG-------------ICLNCADNTIGDHCEFCMSGYHG----DATVG 1807
C C+GH+D+C G +C+ C NT G +CE C Y+ A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 1808 TPRDCLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIPED 1865
+C C C + +F + + G+ + NC+ G CE C Y+
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR-NRR 367
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
+ C C C + PG+ CD + G C+ C + G C+LC PGF G +
Sbjct: 368 PGASIQETCISCECDPD--GAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYAN 424
Query: 1925 -KNCTACICDEFGMA---DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG 1980
+ C C C+ G CD +G C+C P V+G KCD+CAP HW L +G GC PC C
Sbjct: 425 PQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1981 -IASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCDHCNCNTGYSVGF 2034
S + C +G G C QC + GC C+C+ + G
Sbjct: 485 PHNSPQPTVQPVHRAVPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 2035 MCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
C+ A+G+C C PG+ G +CD+C +R C+ C C
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQC-QRGYCNRYPVCVACHPC 584
Score = 147 bits (357), Expect = 6e-34
Identities = 95/307 (30%), Positives = 134/307 (43%), Gaps = 49/307 (15%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNLNGTEGEHCTPT------- 421
C C+ P+C CA Y + P C+ C CN +E H P
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCN-GHSETCHFDPAVFAASQG 337
Query: 422 --DGLCP-CKYNYAGKSCEICEDGYY---------SPECKNCECNTVGSVSYV-CDKLTG 468
G+C C+ + GK+CE C+ Y+ C +CEC+ G+V CD +TG
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 469 DCTCKSKYSGRTCNQCQAG-----YYNYPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGF 522
C CK G C+ C+ G Y N C C+C+ G+ + CD+ SG+C+C
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCD--- 578
GP+CDQC ++ G+ C PC CDP S + + C FGG C
Sbjct: 458 VGPKCDQCAPYHWKLASGQG--CEPCACDPHNSPQPTVQPVHRAVPCREGFGGLMCSAAA 515
Query: 579 --QCSPGYYK--YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYN-Y 632
QC Y C +C+CD G+ G CD +G C C+ G +CD C+ + N Y
Sbjct: 516 IRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRY 575
Query: 633 PACEECN 639
P C C+
Sbjct: 576 PVCVACH 582
Score = 134 bits (323), Expect = 8e-30
Identities = 90/300 (30%), Positives = 125/300 (41%), Gaps = 46/300 (15%)
Query: 424 LCPCKYNYAGKSCEICE-----------DGYYSPECKNCECNTVGSVSYVCDKLT----- 467
+C C++N AG +CE C +G + EC+ C+CN + +
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 468 ---GDC-TCKSKYSGRTCNQCQAGYYN--------YPTCKPCNCDTSGTEPSI-CDDVSG 514
G C C+ G+ C +CQ Y+ TC C CD G P CD V+G
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTG 397
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST-STSCSAD-GKCNCLTNF 572
QC+CK G RCD C G+ + C C+C+ GS C + G+C CL N
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 573 GGAQCDQCSPGYYKYPD---CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT---- 624
G +CDQC+P ++K C C CD S T + C+ F G C
Sbjct: 458 VGPKCDQCAPYHWKLASGQGCEPCACDPHNSPQPTVQPVHRAVPCREGFGGLMCSAAAIR 517
Query: 625 -CREQFYNYPA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
C ++ Y A C C+CD RG GC A C C+ + G C+ C+ Y N
Sbjct: 518 QCPDRTYGDVATGCRACDCDFRGTEGP--GCDK--ASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 128 bits (310), Expect = 3e-28
Identities = 95/315 (30%), Positives = 133/315 (42%), Gaps = 49/315 (15%)
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNC---------D 551
PS V C+C+ GP C++C Y + G++ +C C+C D
Sbjct: 269 PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFD 328
Query: 552 PTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYK--------YPDCLSCNCDVSGSI- 601
P ++ + G C NC + G C++C Y++ C+SC CD G++
Sbjct: 329 PAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 602 GSTCDD-NGLCHCKSNFDGAKCDTCREQF----YNYP-ACEECNCDPRGVTASFAGCGSV 655
G+ CD G C CK + G +CD C+ F Y P C C+C+ G C
Sbjct: 389 GAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMP-CDE- 446
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
+G C C V G C+ C P +W L GCE C C+ NS + V
Sbjct: 447 ESGR-CLCLPNVVGPKCDQCAPYHWKLASGQ--GCEPCACD---PHNSPQPTVQPVHRAV 500
Query: 716 -CKQHVGERQCD-----QCLDGFYRLQTNDVF-GCTECDCDIGGSIDNNCDKTTGQCHCH 768
C++ G C QC D Y DV GC CDCD G+ CDK +G+C C
Sbjct: 501 PCREGFGGLMCSAAAIRQCPDRTY----GDVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
Query: 769 SRVEGRRCDQPIRAH 783
+ G RCDQ R +
Sbjct: 557 PGLTGPRCDQCQRGY 571
Score = 125 bits (302), Expect = 3e-27
Identities = 88/309 (28%), Positives = 121/309 (39%), Gaps = 43/309 (13%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G +CE+CA + P + C C CNGHS+ C +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDATVGT--PRDCLICACPMPYPSNNF-ALSCDLS 1833
G+C NC D+T G +CE C Y + G C+ C C P CD
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD---PDGAVPGAPCDPV 395
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
C C+ G RC+ C G+ G+ C C+C+ + + CD
Sbjct: 396 TG----QCVCKEHVQGERCDLCKPGFTGL----TYANPQGCHRCDCN-ILGSRRDMPCDE 446
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTGTCVCRP 1951
+G CL C+ N G C+ CAP ++ + C C CD CR
Sbjct: 447 ESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSPQPTVQPVHRAVPCRE 504
Query: 1952 GVIGEKCDRCA----PDHWGLNTGLGCTPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQC 2006
G G C A PD + GC C+C +E CD +G+C C G+TG +C
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 2007 DQCAAGFWN 2015
DQC G+ N
Sbjct: 565 DQCQRGYCN 573
Score = 104 bits (249), Expect = 7e-21
Identities = 61/197 (30%), Positives = 84/197 (42%), Gaps = 21/197 (10%)
Query: 1340 CLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-CPSTAI-- 1393
C CD G+ C+ GQC CK +V G C C+ G+ G P CH C +
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1394 -----CDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
CD+ +G C+C NV G CD+C PY + +GC+ C C+P Q +
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHN--SPQPTVQPV 496
Query: 1448 SGKCACRENVRGRVCD-----HCVPGHY--AFPDCYQCTCNRHGTTYDVCDQNTAQCYCK 1500
CRE G +C C Y C C C+ GT CD+ + +C C+
Sbjct: 497 HRAVPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
Query: 1501 TNVRGQACDTCKEEYFN 1517
+ G CD C+ Y N
Sbjct: 557 PGLTGPRCDQCQRGYCN 573
Score = 103 bits (248), Expect = 9e-21
Identities = 61/194 (31%), Positives = 87/194 (44%), Gaps = 20/194 (10%)
Query: 610 LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVT-----ASFAGCGS 654
+C C+ N G C+ C + N P C+ C+C+ T A FA
Sbjct: 278 VCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQG 337
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF---GCEQCNCNLAGTLNSLGACNTKS 711
G C+D +G+ C C+ Y+ + C C C+ G + C+ +
Sbjct: 338 AYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPG-APCDPVT 396
Query: 712 GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS-IDNNCDKTTGQCHCHSR 770
GQCVCK+HV +CD C GF L + GC CDC+I GS D CD+ +G+C C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 771 VEGRRCDQPIRAHY 784
V G +CDQ H+
Sbjct: 457 VVGPKCDQCAPYHW 470
Score = 103 bits (246), Expect = 2e-20
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 38/208 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFP----------NCRPCHC----------PSTAICDDN- 1397
C C+ N G C C Y P C+ C C P+
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 1398 --GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
G+C C + EG+NC+RC+ + F +Q C C C+P G V C+ +G
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-PCDPVTG 397
Query: 1450 KCACRENVRGRVCDHCVPGH----YAFPD-CYQCTCNRHGTTYDV-CDQNTAQCYCKTNV 1503
+C C+E+V+G CD C PG YA P C++C CN G+ D+ CD+ + +C C NV
Sbjct: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNV 457
Query: 1504 RGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
G CD C ++ L + GC C C
Sbjct: 458 VGPKCDQCAPYHWKLA--SGQGCEPCAC 483
Score = 87.4 bits (207), Expect = 9e-16
Identities = 53/166 (31%), Positives = 71/166 (42%), Gaps = 24/166 (14%)
Query: 1389 PSTAICDDNGMCICPKNVEGENCDRCKPYTFN--FDVQRGCDDCNCNPLGVVGNQLQCEA 1446
PSTA+ + +C+C N G NC+RC P+ N + G D C G+ C
Sbjct: 269 PSTAV-QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF 327
Query: 1447 D-----------SGKCA-CRENVRGRVCDHCV--------PGHYAFPDCYQCTCNRHGTT 1486
D G C CR++ G+ C+ C PG C C C+ G
Sbjct: 328 DPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV 387
Query: 1487 YDV-CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD T QC CK +V+G+ CD CK + L NP GC +C C
Sbjct: 388 PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 83.0 bits (196), Expect = 2e-14
Identities = 50/181 (27%), Positives = 76/181 (41%), Gaps = 18/181 (9%)
Query: 1313 YISPNETGLCREAMFSITSEYNSGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCS 1371
++ LC+ +T G C C+ +GS ++ C+ G+C C PNV+G C
Sbjct: 404 HVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCD 463
Query: 1372 ACRTGYYGFPN---CRPCHC-----PSTAICDDNGMCICPKNVEGENCD-----RCKPYT 1418
C ++ + C PC C P + + C + G C +C T
Sbjct: 464 QCAPYHWKLASGQGCEPCACDPHNSPQPTVQPVHRAVPCREGFGGLMCSAAAIRQCPDRT 523
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQ 1477
+ DV GC C+C+ G G C+ SG+C CR + G CD C G+ +P C
Sbjct: 524 YG-DVATGCRACDCDFRGTEGP--GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 1478 C 1478
C
Sbjct: 581 C 581
Score = 65.3 bits (152), Expect = 4e-09
Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 17/154 (11%)
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY----WNLQE-YNPFGCEQCN 694
C P+ AS +V ++C C+ G C C P Y W E + C++C+
Sbjct: 259 CAPKP-GASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 695 CN-LAGTLNSLGACNTKS-----GQC-VCKQHVGERQCDQCLDGFYRLQTNDVF---GCT 744
CN + T + A S G C C+ H + C++C ++R + C
Sbjct: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 745 ECDCDIGGSIDN-NCDKTTGQCHCHSRVEGRRCD 777
C+CD G++ CD TGQC C V+G RCD
Sbjct: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Score = 53.2 bits (122), Expect = 2e-05
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYG-FPNCRPCH 1387
+G R C CDF G+ C+ G+C C+P + G C C+ GY +P C CH
Sbjct: 529 TGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
Score = 46.8 bits (106), Expect = 0.001
Identities = 32/108 (29%), Positives = 40/108 (37%), Gaps = 13/108 (12%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-----CRTGYYG--FPNCRPCHC 1388
G PC CD S + PC+ G CSA C YG CR C C
Sbjct: 477 GCEPCACDPHNSPQPTVQPVHRAVPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDC 536
Query: 1389 PSTAI----CDD-NGMCICPKNVEGENCDRC-KPYTFNFDVQRGCDDC 1430
CD +G C+C + G CD+C + Y + V C C
Sbjct: 537 DFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
>AF172277-3|AAF22284.1| 761|Homo sapiens laminin beta 1 related
protein protein.
Length = 761
Score = 232 bits (567), Expect = 2e-59
Identities = 148/507 (29%), Positives = 239/507 (47%), Gaps = 73/507 (14%)
Query: 53 DDRRTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKMGNSPRPELWVLEKSTDYGKT 112
D + WWQS G+ + V++ +DL F +++ + + RP ++E+STDYG
Sbjct: 87 DREKKWWQS---ENGLDH--VSIRLDLEALFRFSHLILTF-KTFRPAAMLVERSTDYGHN 140
Query: 113 FKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDR-PS 171
+K ++YF+ +DC F + ++C ++YS I P GE+ + +L+
Sbjct: 141 WKVFKYFA---KDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEI 197
Query: 172 SNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRC 231
N Y S +Q+ TN+R+ + + LG + RQ+ ++ + Y+Y++ ++ + G C
Sbjct: 198 ENPY--SPYIQDLVTLTNLRINFTKL-HTLGDALLGRRQNDSLDK-YYYALYEMIVRGSC 253
Query: 232 MCNGHADTCEPAD--------PAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNW 283
CNGHA C P P G ++ C CQHNT GP C +C F+ WR + +
Sbjct: 254 FCNGHASECRPMQKMRGDVFSPPGMVHGQ-CVCQHNTDGPNCERCKDFFQDAPWRPAADL 312
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+C C+C++H++ C +D ++ + GG C +CQHNTEG +C++CRP
Sbjct: 313 QDNACRSCSCNSHSSRCHFD-------MTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 365
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+YR D L DP+ C ES CEC P+ + + G
Sbjct: 366 FYR------DPLKTIS----DPYA----CIRESPACECDPD------GTISGGI------ 399
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPE------CKNCECNTVG 457
C + + G G C CK N G C+ C+ +Y C+ C+CN +G
Sbjct: 400 --CVSHSDPALGS----VAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLG 453
Query: 458 SVSYV-CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT----CKPCNCDTSGTEPSICDDV 512
S+ ++ CD TG C C S +G C +C GY+ C PC+CD G ++C
Sbjct: 454 SLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPK 513
Query: 513 SGQCICKAGFGGPRCDQCLSGYYMQVL 539
+GQC C+ G C + GY+ L
Sbjct: 514 NGQCECRPHVTGRSCSEPAPGYFFAPL 540
Score = 170 bits (413), Expect = 9e-41
Identities = 97/279 (34%), Positives = 136/279 (48%), Gaps = 43/279 (15%)
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYP----------DCLSCNC---------DVSGSIGST 604
G+C C N G C++C + P C SC+C D++ + S
Sbjct: 281 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 340
Query: 605 CDDNGLCH-CKSNFDGAKCDTCREQFYNYP--------AC----EECNCDPRG------- 644
G+C C+ N +G CD CR FY P AC C CDP G
Sbjct: 341 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACECDPDGTISGGIC 400
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
V+ S GSV AG+ C CK+ V+G C+ CKP ++ L +P GC+ C+CN G+L L
Sbjct: 401 VSHSDPALGSV-AGQ-CLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL 458
Query: 705 GACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C+ +GQC+C +V C++C G++ L N + GC+ CDCDIGG+ N C GQ
Sbjct: 459 -TCDVDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDCDIGGAYSNVCSPKNGQ 516
Query: 765 CHCHSRVEGRRCDQPIRAHYFPTLHQFQYEVEDGVTQSG 803
C C V GR C +P ++F L+ + YE E+ T G
Sbjct: 517 CECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQG 555
Score = 132 bits (319), Expect = 2e-29
Identities = 81/247 (32%), Positives = 108/247 (43%), Gaps = 35/247 (14%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP--EDTDLHTGDYCKPCNCSGNIN------PQDPGSCD 1892
C CQ G CE C + P DL + C+ C+C+ + + S
Sbjct: 283 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQD-NACRSCSCNSHSSRCHFDMTTYLASGG 341
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--------KNCTACICDEFGMAD---C- 1940
G C C +NT G C+ C P FY D + + + AC CD G C
Sbjct: 342 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACECDPDGTISGGICV 401
Query: 1941 -------DSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG--LGCTPCNCGIASEST--QCD 1989
S G C+C+ V G KCD+C P+H+GL+ LGC PC+C CD
Sbjct: 402 SHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCD 461
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMCN-ATGQCECLP 2046
D GQC C VTG C++C G+W GC C+C+ G + +C+ GQCEC P
Sbjct: 462 VDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRP 521
Query: 2047 GVIGEKC 2053
V G C
Sbjct: 522 HVTGRSC 528
Score = 128 bits (309), Expect = 4e-28
Identities = 97/317 (30%), Positives = 141/317 (44%), Gaps = 49/317 (15%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H +EC P + G G +C+ CQHNT+G NC +C+ + P+
Sbjct: 253 CFCNGHASECR--PMQKMRGDVFSPPGMVHG--QCV-CQHNTDGPNCERCKDFFQDAPWR 307
Query: 350 KRWDELD-VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
D D C+ C C+ H S RC F + A G C+ C
Sbjct: 308 PAADLQDNACRSCSCNSH---------SSRCH----FDMT--TYLASGGLSGGVCEDCQH 352
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSY-VC---- 463
N TEG+HC D P Y K+ I + E CEC+ G++S +C
Sbjct: 353 N---TEGQHC---DRCRPLFYRDPLKT--ISDPYACIRESPACECDPDGTISGGICVSHS 404
Query: 464 ----DKLTGDCTCKSKYSGRTCNQCQAGYYNYPT-----CKPCNCDTSGTEPSI-CDDVS 513
+ G C CK G C+QC+ +Y C+PC+C+ G+ P + CD +
Sbjct: 405 DPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDT 464
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQ-CVPCNCDPTGSTSTSCSA-DGKCNCLTN 571
GQC+C + G C++C GY+ LG C PC+CD G+ S CS +G+C C +
Sbjct: 465 GQCLCLSYVTGAHCEECTVGYWG--LGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPH 522
Query: 572 FGGAQCDQCSPGYYKYP 588
G C + +PGY+ P
Sbjct: 523 VTGRSCSEPAPGYFFAP 539
Score = 124 bits (299), Expect = 6e-27
Identities = 94/288 (32%), Positives = 124/288 (43%), Gaps = 42/288 (14%)
Query: 1765 CQCNGHSDQC--------DVNT------GICLNCADNTIGDHCEFCMSGYHGDATVGTPR 1810
C CNGH+ +C DV + G C+ C NT G +CE C + DA
Sbjct: 253 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQ-DAPWRPAA 310
Query: 1811 D-----CLICACPMPYPSNNFALSCDLSENGSL--ISCNCQPGYGGARCEYCAAGYYGIP 1863
D C C+C +F ++ L+ G + +CQ G C+ C +Y P
Sbjct: 311 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDP 370
Query: 1864 EDT--DLHTGDYCKP-CNC------SGNI--NPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
T D + P C C SG I + DP + S+ G CL C N GA C+
Sbjct: 371 LKTISDPYACIRESPACECDPDGTISGGICVSHSDP-ALGSVAGQCL-CKENVEGAKCDQ 428
Query: 1913 CAPGFYG-DAIFSKNCTACICDEFG---MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
C P YG A C C C+ G CD TG C+C V G C+ C +WGL
Sbjct: 429 CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL 488
Query: 1969 NTGL-GCTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFW 2014
L GC+PC+C I S C NGQC C VTG+ C + A G++
Sbjct: 489 GNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 536
Score = 114 bits (275), Expect = 5e-24
Identities = 77/261 (29%), Positives = 109/261 (41%), Gaps = 35/261 (13%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQC--DVNT------ 1778
+C C G +CE+C + P C C CN HS +C D+ T
Sbjct: 282 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 341
Query: 1779 ---GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCL----ICAC-PMPYPSNNFAL 1828
G+C +C NT G HC+ C ++ D T+ P C+ C C P S +
Sbjct: 342 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACECDPDGTISGGICV 401
Query: 1829 SCDLSENGSLI-SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQD 1887
S GS+ C C+ GA+C+ C +YG+ L C+PC+C+ +
Sbjct: 402 SHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG----CQPCDCN-PLGSLP 456
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTG 1945
+CD G CL C++ GA C C G++G C+ C CD G C G
Sbjct: 457 FLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNG 515
Query: 1946 TCVCRPGVIGEKCDRCAPDHW 1966
C CRP V G C AP ++
Sbjct: 516 QCECRPHVTGRSCSEPAPGYF 536
Score = 108 bits (259), Expect = 4e-22
Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 32/202 (15%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASF-----AGC 652
+G C C+ N DG C+ C++ F + P AC C+C+ F
Sbjct: 280 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 339
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWN--LQEY-NPFGC----EQCNCNLAGTLNSLG 705
G + G C+ +G+ C+ C+PL++ L+ +P+ C C C+ GT++ G
Sbjct: 340 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACECDPDGTISG-G 398
Query: 706 ACNTKS--------GQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSID-N 756
C + S GQC+CK++V +CDQC Y L D GC CDC+ GS+
Sbjct: 399 ICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL 458
Query: 757 NCDKTTGQCHCHSRVEGRRCDQ 778
CD TGQC C S V G C++
Sbjct: 459 TCDVDTGQCLCLSYVTGAHCEE 480
Score = 102 bits (245), Expect = 2e-20
Identities = 66/209 (31%), Positives = 90/209 (43%), Gaps = 35/209 (16%)
Query: 1342 CDFMGSTELECNTF-GGQCP-CKPNVIGRTCSACRTGYYGFP-----------------N 1382
C F +T L GG C C+ N G+ C CR +Y P
Sbjct: 329 CHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACE 388
Query: 1383 CRPCHCPSTAICDDN---------GMCICPKNVEGENCDRCKP--YTFNFDVQRGCDDCN 1431
C P S IC + G C+C +NVEG CD+CKP Y + GC C+
Sbjct: 389 CDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCD 448
Query: 1432 CNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD----CYQCTCNRHGTTY 1487
CNPLG + L C+ D+G+C C V G C+ C G++ + C C C+ G
Sbjct: 449 CNPLGSLPF-LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYS 507
Query: 1488 DVCDQNTAQCYCKTNVRGQACDTCKEEYF 1516
+VC QC C+ +V G++C YF
Sbjct: 508 NVCSPKNGQCECRPHVTGRSCSEPAPGYF 536
Score = 97.9 bits (233), Expect = 6e-19
Identities = 67/222 (30%), Positives = 94/222 (42%), Gaps = 49/222 (22%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPS-TAICD---------- 1395
GQC C+ N G C C+ + P CR C C S ++ C
Sbjct: 281 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 340
Query: 1396 --DNGMCI-CPKNVEGENCDRCKPYTFNFDVQRGCDD---------CNCNPLGVVGNQLQ 1443
G+C C N EG++CDRC+P + ++ D C C+P G + +
Sbjct: 341 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACECDPDGTISGGI- 399
Query: 1444 CEADS--------GKCACRENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTT-YDV 1489
C + S G+C C+ENV G CD C P HY C C CN G+ +
Sbjct: 400 CVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT 459
Query: 1490 CDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
CD +T QC C + V G C+ C Y+ L ++ GC+ C C
Sbjct: 460 CDVDTGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGCSPCDC 500
Score = 96.7 bits (230), Expect = 1e-18
Identities = 77/286 (26%), Positives = 116/286 (40%), Gaps = 58/286 (20%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
G C C++N G +CE C+D + + + + D C+C S S
Sbjct: 281 GQCVCQHNTDGPNCERCKDFFQDAPWR--------PAADLQDNACRSCSCNSHSS----- 327
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVL 539
+C Y + G +C+D C+ G CD+C +Y ++ +
Sbjct: 328 RCHFDMTTYLA-------SGGLSGGVCED------CQHNTEGQHCDRCRPLFYRDPLKTI 374
Query: 540 GRERQCV----PCNCDPTGSTSTS-C---------SADGKCNCLTNFGGAQCDQCSPGYY 585
C+ C CDP G+ S C S G+C C N GA+CDQC P +Y
Sbjct: 375 SDPYACIRESPACECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY 434
Query: 586 KYP-----DCLSCNCDVSGSIG-STCD-DNGLCHCKSNFDGAKCDTCREQFY----NYPA 634
C C+C+ GS+ TCD D G C C S GA C+ C ++ +
Sbjct: 435 GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG 494
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYW 680
C C+CD G ++ P C+C+ V GR C++ P Y+
Sbjct: 495 CSPCDCDIGGAYSNVCS----PKNGQCECRPHVTGRSCSEPAPGYF 536
Score = 85.8 bits (203), Expect = 3e-15
Identities = 46/129 (35%), Positives = 62/129 (48%), Gaps = 14/129 (10%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI----CD-DNGMCICPKN 1405
GQC CK NV G C C+ +YG C+PC C P ++ CD D G C+C
Sbjct: 413 GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY 472
Query: 1406 VEGENCDRCK-PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH 1464
V G +C+ C Y + GC C+C+ G N C +G+C CR +V GR C
Sbjct: 473 VTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSN--VCSPKNGQCECRPHVTGRSCSE 530
Query: 1465 CVPGHYAFP 1473
PG++ P
Sbjct: 531 PAPGYFFAP 539
Score = 74.9 bits (176), Expect = 5e-12
Identities = 52/170 (30%), Positives = 70/170 (41%), Gaps = 35/170 (20%)
Query: 1397 NGMCICPKNVEGENCDRCK------PYTFNFDVQ-RGCDDCNCNP------LGVVGNQLQ 1443
+G C+C N +G NC+RCK P+ D+Q C C+CN +
Sbjct: 280 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 339
Query: 1444 CEADSGKCA-CRENVRGRVCDHCVPGHYAFP-----DCYQCT-------CNRHGT-TYDV 1489
G C C+ N G+ CD C P Y P D Y C C+ GT + +
Sbjct: 340 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACECDPDGTISGGI 399
Query: 1490 CDQNT--------AQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
C ++ QC CK NV G CD CK ++ L +P GC C C
Sbjct: 400 CVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDC 449
Score = 72.9 bits (171), Expect = 2e-11
Identities = 66/223 (29%), Positives = 88/223 (39%), Gaps = 46/223 (20%)
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDA-------IFSKNCTACICDEFGM-ADCDSTT- 1944
++G C+ C +NT G C C F+ DA + C +C C+ D TT
Sbjct: 279 VHGQCV-CQHNTDGPNCERCKD-FFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTY 336
Query: 1945 --------GTCV-CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDN--- 1992
G C C+ G+ CDRC P + P C S + +CD D
Sbjct: 337 LASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIRESPACECDPDGTIS 396
Query: 1993 ----------------GQCRCAKGVTGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVG 2033
GQC C + V G +CDQC + + GC C+CN S+
Sbjct: 397 GGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLP 456
Query: 2034 FM-CNA-TGQCECLPGVIGEKCDRCP-ERWVLIPQ-EGCLECD 2072
F+ C+ TGQC CL V G C+ C W L GC CD
Sbjct: 457 FLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCD 499
Score = 70.5 bits (165), Expect = 1e-10
Identities = 49/138 (35%), Positives = 58/138 (42%), Gaps = 21/138 (15%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCNGHSD----QCDVNTGICLNCAD 1786
+C C G C+QC HY L P G C PC CN CDV+TG CL C
Sbjct: 414 QCLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTGQCL-CLS 471
Query: 1787 NTIGDHCEFCMSGYHGDATVGTP-RDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
G HCE C GY G +G C C C + +N C +NG C C+P
Sbjct: 472 YVTGAHCEECTVGYWG---LGNHLHGCSPCDCDIGGAYSNV---CS-PKNG---QCECRP 521
Query: 1846 GYGGARCEYCAAGYYGIP 1863
G C A GY+ P
Sbjct: 522 HVTGRSCSEPAPGYFFAP 539
Score = 63.7 bits (148), Expect = 1e-08
Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTE-LECNTFGGQCPCKPNVIGRTCSACRTGYYGF 1380
C+ + +++ G +PC C+ +GS L C+ GQC C V G C C GY+G
Sbjct: 429 CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL 488
Query: 1381 PN----CRPCHCP-----STAICDDNGMCICPKNVEGENCDRCKPYTF 1419
N C PC C S NG C C +V G +C P F
Sbjct: 489 GNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 536
Score = 49.6 bits (113), Expect = 2e-04
Identities = 20/46 (43%), Positives = 26/46 (56%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
G PC CD G+ C+ GQC C+P+V GR+CS GY+ P
Sbjct: 494 GCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 539
>BC026237-1|AAH26237.1| 324|Homo sapiens Unknown (protein for
IMAGE:4702204) protein.
Length = 324
Score = 210 bits (512), Expect = 9e-53
Identities = 98/220 (44%), Positives = 125/220 (56%), Gaps = 11/220 (5%)
Query: 1746 SCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
+ E+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G P+ C C CP+P+ + NFA SC +NG+ + C C Y G CE CA GYYG P
Sbjct: 123 RGAPQFCQPCPCPLPHLA-NFAESC-YRKNGA-VRCICNENYAGPNCERCAPGYYGNP-- 177
Query: 1866 TDLHTGDYCKPCNCSGNINPQ-DPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS 1924
L G CK C+CSGN +P CD + G C C+ NT G C CAPG+YGDA +
Sbjct: 178 --LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1925 KNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPD 1964
KNC C C G CDS TG C+ CD+C D
Sbjct: 236 KNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKCVWD 272
Score = 105 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 31/204 (15%)
Query: 387 PPDCSSCAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGY 443
PP C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 444 Y------SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQCQAGYYNYP 492
+P+ C+ C C + + + C + G C C Y+G C +C GYY P
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 493 -----TCKPCNCDTSGTEPSI----CDDVSGQC-ICKAGFGGPRCDQCLSGYYMQVLGRE 542
TCK C+C + ++P++ CD+V+GQC C G +C++C GYY
Sbjct: 178 LLIGSTCKKCDC-SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIA 235
Query: 543 RQCVPCNC--DPTGSTSTSCSADG 564
+ C CNC P S + C +G
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEG 259
Score = 105 bits (253), Expect = 2e-21
Identities = 68/203 (33%), Positives = 95/203 (46%), Gaps = 32/203 (15%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 79 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 133
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAPDHWG--LNTGLGCTPCNCGIAS 1983
C +A+ C G C+C G C+RCAP ++G L G C C+C S
Sbjct: 134 CPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
Query: 1984 EST----QCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMC 2036
+ CD+ GQCR C + TG +C++CA G++ + C CNC G C
Sbjct: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PC 248
Query: 2037 NA-TGQC--ECLPGVIGEKCDRC 2056
++ TG+C E G CD+C
Sbjct: 249 DSVTGECLEEGFEPPTG--CDKC 269
Score = 101 bits (243), Expect = 4e-20
Identities = 68/214 (31%), Positives = 91/214 (42%), Gaps = 40/214 (18%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 79 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 348 YGKRWDELDVCQPCQCD-PHFS--TGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
+ + CQPC C PH + +C ++G RC C + P+C CA GY+ P
Sbjct: 121 SIRGAPQF--CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Query: 402 ----NCKPCTCNLNGTEG---EHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPE--CKNC 451
CK C C+ N E C G C C N G CE C GYY KNC
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
Query: 452 E-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
CN G CD +TG+C + C++C
Sbjct: 239 AVCNCGGG---PCDSVTGECLEEGFEPPTGCDKC 269
Score = 92.7 bits (220), Expect = 2e-17
Identities = 66/211 (31%), Positives = 90/211 (42%), Gaps = 24/211 (11%)
Query: 435 SCEICEDGYY---SPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGYYN 490
+ E C G++ S EC C+CN G+ S C +G C C+ +G C +C GY
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCN--GN-SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 491 YPT------CKPCNCDTS--GTEPSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLG 540
C+PC C C +G +CIC + GP C++C GYY L
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 541 RERQCVPCNC----DPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
C C+C DP G+C NCL N G +C++C+PGYY ++ NC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 596 DVSGSIGSTCDD-NGLCHCKSNFDGAKCDTC 625
V G CD G C + CD C
Sbjct: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 82.6 bits (195), Expect = 2e-14
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 67 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVPGHYAFP-----DCY 1476
C C C PL + N + C +G +C C EN G C+ C PG+Y P C
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
Query: 1477 QCTCNRH---GTTYDVCDQNTAQC-YCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCF 1532
+C C+ + ++ CD+ T QC C N G C+ C Y+ C C C
Sbjct: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
Query: 1533 G 1533
G
Sbjct: 245 G 245
Score = 81.0 bits (191), Expect = 7e-14
Identities = 59/223 (26%), Positives = 93/223 (41%), Gaps = 32/223 (14%)
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPG 583
P ++C +G++ + G +CVPC+C+ G+++ G C +C N G C++C G
Sbjct: 62 PAAEKCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 584 YYK-----YPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCDTCREQFYNY 632
Y P C C C + + +C NG C C N+ G C+ C +Y
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 633 P-----ACEECNCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
P C++C+C F C V G+ C G C C P Y+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEV-TGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL 729
C CNC G G C++ +G+C+ + CD+C+
Sbjct: 236 K-NCAVCNC--GG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
Score = 79.8 bits (188), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 1729 RATSVEECQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQCNGHSD------QCDVNTG 1779
R C C Y G +CE+CA G+Y P C C C+G+SD CD TG
Sbjct: 148 RKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
Score = 79.4 bits (187), Expect = 2e-13
Identities = 61/204 (29%), Positives = 84/204 (41%), Gaps = 33/204 (16%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYY-----GFPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 82 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 140
Query: 1395 D-------DNG--MCICPKNVEGENCDRCKPYTFNFDVQRG--CDDCNCNPLGVVGNQLQ 1443
+ NG CIC +N G NC+RC P + + G C C+C+ +
Sbjct: 141 NFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFE 200
Query: 1444 -CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 255
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDD 1521
+ CD C ++L DD
Sbjct: 256 LEEGFEPPTGCDKC---VWDLTDD 276
Score = 77.4 bits (182), Expect = 9e-13
Identities = 56/174 (32%), Positives = 71/174 (40%), Gaps = 28/174 (16%)
Query: 1738 CPRAYRGLSCEQCAEGH----YRLPSGFCVPCQC-----NGHSDQCDVNTGI--CLNCAD 1786
C R G CE+C +G+ R FC PC C ++ C G C+ C +
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNE 159
Query: 1787 NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
N G +CE C GY+G+ + C C C N CD G NC
Sbjct: 160 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCD-EVTGQ--CRNCLRN 215
Query: 1847 YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 216 TTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 257
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 1909 ACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG 1967
A C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 63 AAEKCNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 1968 ---LNTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN---Y 2016
C PC C +A+ + C NG +C C + G C++CA G++
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 2017 TKDGCDHCNCNTGYSVGFM---CN-ATGQC-ECLPGVIGEKCDRC 2056
C C+C+ + C+ TGQC CL G KC+RC
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 68.9 bits (161), Expect = 3e-10
Identities = 59/204 (28%), Positives = 78/204 (38%), Gaps = 39/204 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 82 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 131
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + S R G +C+ C N G NC +C P Y YG
Sbjct: 132 CPCPL--------PHLANFAESC---YRKNGAVRCI-CNENYAGPNCERCAPGY---YGN 176
Query: 351 RWDELDVCQPCQC----DPHFSTGNCEEESGRC-ECRPEFQPPDCSSCAYGYFD----YP 401
C+ C C DP+ +C+E +G+C C C CA GY+
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 402 NCKPCTCNLNGTEGEHCTPTDGLC 425
NC C C G C G C
Sbjct: 237 NCAVCNCG-----GGPCDSVTGEC 255
Score = 63.7 bits (148), Expect = 1e-08
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY-WN 681
+ C F++ + E CD G + GS G C+ G C C Y +
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLD-GS---GYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHVGERQCDQCLDGFYRLQTND 739
P C+ C C L N +C K+G +C+C ++ C++C G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 740 VFGCTECDCDIGGSIDN----NCDKTTGQC-HCHSRVEGRRCDQPIRAHY 784
C +CDC G S N +CD+ TGQC +C G +C++ +Y
Sbjct: 181 GSTCKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 58.4 bits (135), Expect = 5e-07
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 27/147 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C N GP C +C G+ I +C+ C+C ++ DP + +
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNL----IFE 200
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D + E G+C NC NT G C +C P YY + C C C G C+
Sbjct: 201 DCD---EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCD 249
Query: 374 EESGRCECRPEFQPP-DCSSCAYGYFD 399
+G C F+PP C C + D
Sbjct: 250 SVTGEC-LEEGFEPPTGCDKCVWDLTD 275
Score = 57.6 bits (133), Expect = 8e-07
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 24/145 (16%)
Query: 1339 PCLCDFMGSTELECNTFGG--QCPCKPNVIGRTCSACRTGYYGFP-----NCRPCHCPST 1391
PC + + C G +C C N G C C GYYG P C+ C C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN 192
Query: 1392 A-------ICDD-NGMC-ICPKNVEGENCDRCKP-YTFNFDVQRGCDDCNCNPLGVVGNQ 1441
+ CD+ G C C +N G C+RC P Y + + + C CNC G
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG-----GG- 246
Query: 1442 LQCEADSGKCACRENVRGRVCDHCV 1466
C++ +G+C CD CV
Sbjct: 247 -PCDSVTGECLEEGFEPPTGCDKCV 270
Score = 38.7 bits (86), Expect = 0.39
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCN---------TGY 2030
G ++ Q + + R A G ++C AGF++ C C+CN +GY
Sbjct: 38 GSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGY 97
Query: 2031 SVGFMCNATGQ-CE-CLPGVIGEKCDRCPE 2058
V N TG+ CE CL G IG+ P+
Sbjct: 98 CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
>AB208922-1|BAD92159.1| 1853|Homo sapiens laminin alpha 2 subunit
precursor variant protein.
Length = 1853
Score = 206 bits (504), Expect = 9e-52
Identities = 310/1406 (22%), Positives = 538/1406 (38%), Gaps = 131/1406 (9%)
Query: 1901 CVNNTAGAACNLCAPGFY------GDAIFSKNCTACI-CDEFGMAD-CDSTTGTCV-CRP 1951
C +G +C C PGFY G C+ C G + CD T C C+
Sbjct: 117 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQH 176
Query: 1952 GVIGEKCDRCAPDHWGLNTGL--GCTPCNCGIASESTQCDD-------DNGQCR-CAKGV 2001
G+ C+RCA ++G+ GL C C C + S S D+ +C C +G
Sbjct: 177 HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGY 236
Query: 2002 TGKQCDQCAAGFWNYTKD---GCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCP 2057
G+ C++CA G+ + C C C+ S+ C+ TG C C PG G KCD C
Sbjct: 237 EGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC- 295
Query: 2058 ERWVLIPQEGCLEC-DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQT 2116
+ W C+ C D CT L+ + L ++ + + A N
Sbjct: 296 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK 355
Query: 2117 ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERT 2176
LL P+ A + + + E ++ TL T LL A D ++ A + A+
Sbjct: 356 HLLSPQRAPERLIQLAE--GNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 413
Query: 2177 LAAVRESAREATEVVKHVADLATGL---ELSQQPKVDSALTEARQIRDDIADKDLVPKKQ 2233
++E AR+A V + L L + + + ++ E Q+ ++ K+L +K+
Sbjct: 414 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE 473
Query: 2234 QAEAVFLNTTTQIERM-NFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYT 2292
AE + ++++ F + E + DL+ E L + ++ D D + E T
Sbjct: 474 IAEDELVAAEALLKKVKKLFGESRGENEEMEK---DLR-EKLADYKNKVDDAWDLLREAT 529
Query: 2293 DLAQHTAHTAEELNTKN--RLSKFGNKVNSVTKL--NTAAMG-DLIDAAYDIGNATYNNM 2347
D + A+ +N KN L K V S + NT G D++D A + + N++
Sbjct: 530 DKIRE-ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLAD-EINSI 587
Query: 2348 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRE 2407
+L + S+A HA L + L
Sbjct: 588 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAE---KVSQAESHAAQLNDSSAVLDG 644
Query: 2408 LAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKL----NRILDERV 2463
+ + N S + I+ TKL +L E
Sbjct: 645 ILDEAKNIS--FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA 702
Query: 2464 RPARERSSSLLADATKAQHAV--DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXX 2521
+ ++S +L +A K + V ++ L L E L R +D
Sbjct: 703 KGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIP 762
Query: 2522 XXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVE 2581
+KA + N T + ++ L L K + KLAD K + V+
Sbjct: 763 NDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLK---KNYNKLADSVAKTNAVVK 819
Query: 2582 SHLKN--INDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKLKDLVE---QARTVANRI 2636
KN I D + + + + + ++ E QAR AN I
Sbjct: 820 DPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 879
Query: 2637 QVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKS 2694
+V V+ D T +P + + + ++ +T D + YLG+ K
Sbjct: 880 KVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADNLLFYLGS--------AKF 926
Query: 2695 DDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIR 2754
D++ I ++ G + D+G + P D + D+ WY+++ R GR +S+R
Sbjct: 927 IDFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSYWYRIVASRTGRNGTISVR 981
Query: 2755 ESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIE 2811
+LD +I + + P +TI ++D + L+VGG+ K + F G +
Sbjct: 982 -ALDGPKASIVPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMG 1039
Query: 2812 ELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQS 2870
E + P+GLWNF KG ++ S+ Q FDG GYA ++ P
Sbjct: 1040 ETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---FDGEGYALVSRPIRWYPNI 1096
Query: 2871 NQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+ V+ FRT++ + L+ YL F S+ + DG + + LG+ + V + + +ND
Sbjct: 1097 STVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS--GMASVVSNQNHND 1154
Query: 2929 GKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSADIPSLDTMNFGG--NNKGI 2978
GKW R + ++++ +N + N+ D+ + D + FGG + +
Sbjct: 1155 GKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 1214
Query: 2979 L-QVPDRGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLRFVDV 3035
+V + + GC++ I I+ ++ + + +G+ GC ++ VSF ++ V
Sbjct: 1215 RPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSF-PKPGFVELSPV 1273
Query: 3036 TSE-NPQLTLKFKTAKPNGLLFVYVS-------RTQTAIMPDSISLSLVNGKLVV----- 3082
+ ++ L F T +G++ + R + ++ L G+L V
Sbjct: 1274 PIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVHLSTG 1333
Query: 3083 --VSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD-FDYFSTDTAPPPLHILDGVL 3139
++ + N ++D + H + V + VD+ Y T P+ + L
Sbjct: 1334 ARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVKK--L 1391
Query: 3140 FIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRCG----TTIT 3195
F+GG P + S L + PF GCI + IN ++ P S + GRC
Sbjct: 1392 FVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKLREDE 1450
Query: 3196 TGGVNPDKVTWSIPTSPDVLPMPEPV 3221
G + V P P P PV
Sbjct: 1451 DGAAPAEIVIQPEPVPTPAFPTPTPV 1476
Score = 180 bits (439), Expect = 7e-44
Identities = 109/302 (36%), Positives = 149/302 (49%), Gaps = 35/302 (11%)
Query: 1634 PDVIIAG---PNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAP-----VTRDQFMH 1685
P VII G + ++ + P +G H ++++E+E+ P VTR+ F+
Sbjct: 7 PQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLD 66
Query: 1686 ALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGL 1745
L +I + I+A+Y + ++ +S + +E+ + G + A +E+C CP Y GL
Sbjct: 67 ILYDIHYILIKATYGNFMRQSRISEISMEVA-EQGRGTTMTPP-ADLIEKCDCPLGYSGL 124
Query: 1746 SCEQCAEGHYRLPS-----------GFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
SCE C G YRL S G CVPCQCNGHS CD T IC NC +T GD CE
Sbjct: 125 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE 184
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCN-CQPGYGGARCE 1853
C GY+G G P DC CACP+ SNNF+ SC ++E C C GY G CE
Sbjct: 185 RCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSC-VAEGLDDYRCTACPRGYEGQYCE 242
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
CA GY G P + G C+ C C G++ P CD + G C C G C+
Sbjct: 243 RCAPGYTGSPG----NPGGSCQECECDPYGSL----PVPCDPVTGFC-TCRPGATGRKCD 293
Query: 1912 LC 1913
C
Sbjct: 294 GC 295
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 1482 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 1536
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 1537 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 1592
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 1593 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 1650
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 1651 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 1705
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 1706 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 1765
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 1766 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 1822
Score = 101 bits (243), Expect = 4e-20
Identities = 118/506 (23%), Positives = 199/506 (39%), Gaps = 50/506 (9%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED----TDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C+C GY G CE C G+Y + T T C PC C+G+ + CD
Sbjct: 115 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS-----LCDPETS 169
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV------- 1948
C C ++TAG C CA G+YG N C C C ++ ++ + +CV
Sbjct: 170 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPL--ISSSNNFSPSCVAEGLDDY 227
Query: 1949 ----CRPGVIGEKCDRCAPDHWGL--NTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGV 2001
C G G+ C+RCAP + G N G C C C S CD G C C G
Sbjct: 228 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 287
Query: 2002 TGKQCDQCAAGFWNYTKDGCDHCNCN---TGYSVGFMC---------NATGQCECLPGVI 2049
TG++CD C W + ++G + C TG +G + N TG ++
Sbjct: 288 TGRKCDGCK--HW-HAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKML 344
Query: 2050 GEKCDRCPE-RWVLIPQEGCLECDSCTDA-LIFSVEDLSALLANETMDFKDKADSFFTTQ 2107
+ E + +L PQ + L V +++ LL T D + +
Sbjct: 345 YGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAE 404
Query: 2108 RLNYISNQT-ELLRPKVAQLKTVDIGEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRA 2166
R N + E ++ + V+ + + +TL T + R+ E + D+ I
Sbjct: 405 RTNTRAKSLGEFIKELARDAEAVNEKAIKLN-ETLGTRDEAFERNLEGLQKEIDQMIKEL 463
Query: 2167 AKLAEDAERTLAAVRESAREA-TEVVKHVADLATGLELSQQPKVDSALTEARQIRDDIAD 2225
+ + ++ +A A EA + VK + + G + + L + + DD D
Sbjct: 464 RRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWD 523
Query: 2226 --KDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKD 2283
++ K ++A +F + + + V E K + +++ L D
Sbjct: 524 LLREATDKIREANRLFAVNQKNMTALEKKKEAV-ESGKRQIENTLKEGNDILDEANRLAD 582
Query: 2284 KLDDMLEYT-DLAQHTAHTAEELNTK 2308
+++ +++Y D+ +EELN K
Sbjct: 583 EINSIIDYVEDIQTKLPPMSEELNDK 608
Score = 99.1 bits (236), Expect = 3e-19
Identities = 64/186 (34%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYR----PYGKR-WDELDVCQPCQCDPHFSTGNCEEESGR 378
KC +C G++C C P +YR P G+ L C PCQC+ H S C+ E+
Sbjct: 114 KC-DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSI 170
Query: 379 CE-CRPEFQPPDCSSCAYGYFDY----PN-CKPCTCNLNGTEGEHCTP--TDGL----CP 426
C+ C+ C CA GY+ PN C+ C C L + +GL C
Sbjct: 171 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 230
Query: 427 -CKYNYAGKSCEICEDGYY-SP-----ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGR 479
C Y G+ CE C GY SP C+ CEC+ GS+ CD +TG CTC+ +GR
Sbjct: 231 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 290
Query: 480 TCNQCQ 485
C+ C+
Sbjct: 291 KCDGCK 296
Score = 99.1 bits (236), Expect = 3e-19
Identities = 62/185 (33%), Positives = 81/185 (43%), Gaps = 31/185 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYY---NYP----------TCKPCNCDTSGTEPSICDDVSGQC 516
C C YSG +C C G+Y + P TC PC C+ S+CD + C
Sbjct: 115 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSIC 171
Query: 517 -ICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST---STSCSADG----KCN- 567
C+ G C++C GYY V G C C C S+ S SC A+G +C
Sbjct: 172 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 231
Query: 568 CLTNFGGAQCDQCSPGYYKYP-----DCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAK 621
C + G C++C+PGY P C C CD GS+ CD G C C+ G K
Sbjct: 232 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 291
Query: 622 CDTCR 626
CD C+
Sbjct: 292 CDGCK 296
Score = 96.3 bits (229), Expect = 2e-18
Identities = 71/210 (33%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 1783 NCADNTIGDHCEFCMSGYH------GDATVG-TPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C G CE C+ G++ G T G T C+ C C N + CD +
Sbjct: 116 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC------NGHSSLCDPETS 169
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCS--GNINPQDPGSCDS 1893
I NCQ G CE CA GYYGI + + C+ C C + N P SC +
Sbjct: 170 ---ICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSP-SCVA 221
Query: 1894 INGD---CLKCVNNTAGAACNLCAPGFYGD-AIFSKNCTACICDEFGM--ADCDSTTGTC 1947
D C C G C CAPG+ G +C C CD +G CD TG C
Sbjct: 222 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 281
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPC 1977
CRPG G KCD C HW G C C
Sbjct: 282 TCRPGATGRKCDGC--KHWHAREGWECVFC 309
Score = 89.4 bits (212), Expect = 2e-16
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 39/209 (18%)
Query: 378 RCECRPEFQPPDCSSCAYGYF---DYPN----------CKPCTCNLNGTEGEHCTPTDGL 424
+C+C + C +C G++ P C PC CN + + C P +
Sbjct: 114 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 170
Query: 425 CP-CKYNYAGKSCEICEDGYYS------PECKNCECNTVGSVSYVCDKLTGD------CT 471
C C+++ AG CE C GYY +C+ C C + S + + CT
Sbjct: 171 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 230
Query: 472 -CKSKYSGRTCNQCQAGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
C Y G+ C +C GY P +C+ C CD G+ P CD V+G C C+ G G
Sbjct: 231 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 290
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTG 554
+CD C + + G E CV C + TG
Sbjct: 291 KCDGCKHWHARE--GWE--CVFCGDECTG 315
Score = 85.4 bits (202), Expect = 3e-15
Identities = 66/226 (29%), Positives = 93/226 (41%), Gaps = 37/226 (16%)
Query: 503 GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY---MQVLGRE-----RQCVPCNCDPTG 554
GT + D+ +C C G+ G C+ CL G+Y Q GR CVPC C+ G
Sbjct: 102 GTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN--G 159
Query: 555 STSTSCSADGKC-NCLTNFGGAQCDQCSPGYYKY-----PDCLSCNCDV---SGSIGSTC 605
+S C NC + G C++C+ GYY DC C C + S + +C
Sbjct: 160 HSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC 219
Query: 606 -----DDNGLCHCKSNFDGAKCDTCREQFYNYP-----ACEECNCDPRGVTASFAGCGSV 655
DD C ++G C+ C + P +C+EC CDP G C
Sbjct: 220 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD-- 275
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P C C+ GR C+ CK +W+ +E + C C G L
Sbjct: 276 PVTGFCTCRPGATGRKCDGCK--HWHARE--GWECVFCGDECTGLL 317
Score = 82.6 bits (195), Expect = 2e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 611 CHCKSNFDGAKCDTCREQFYNY--------PACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C C + G C+ C FY P C P + C P +CQ
Sbjct: 115 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--PETSICQ 172
Query: 663 -CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG----QCV-C 716
C+ G C C Y+ + + P C+QC C L + N+ G +C C
Sbjct: 173 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 232
Query: 717 KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + C++C G+ N C EC+CD GS+ CD TG C C GR+C
Sbjct: 233 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 292
Query: 777 D 777
D
Sbjct: 293 D 293
Score = 79.0 bits (186), Expect = 3e-13
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN-------------CRPCHCPS-TAICD-DNGMCI- 1401
+C C G +C AC G+Y + C PC C +++CD + +C
Sbjct: 114 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 173
Query: 1402 CPKNVEGENCDRCKP--YTFNFDVQRGCDDCNCNPLGVVGN-QLQCEA---DSGKC-ACR 1454
C + G+ C+RC Y + C C C + N C A D +C AC
Sbjct: 174 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 233
Query: 1455 ENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
G+ C+ C PG+ P C +C C+ +G+ CD T C C+ G+ CD
Sbjct: 234 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 293
Query: 1510 TCK 1512
CK
Sbjct: 294 GCK 296
Score = 75.8 bits (178), Expect = 3e-12
Identities = 51/151 (33%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 1339 PCLCDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYGF----PN-CRPCHCPSTA 1392
PC C+ G + L C+ C C+ + G C C GYYG PN C+ C CP +
Sbjct: 154 PCQCN--GHSSL-CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 210
Query: 1393 I-------C-----DDNGMCICPKNVEGENCDRCKP-YTFNFDVQRG-CDDCNCNPLGVV 1438
C DD CP+ EG+ C+RC P YT + G C +C C+P G +
Sbjct: 211 SSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL 270
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+ C+ +G C CR GR CD C H
Sbjct: 271 --PVPCDPVTGFCTCRPGATGRKCDGCKHWH 299
Score = 71.3 bits (167), Expect = 6e-11
Identities = 46/167 (27%), Positives = 68/167 (40%), Gaps = 26/167 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C CNGH+ C+P +C+ CQH+T G C +C G+ + I + C+
Sbjct: 155 CQCNGHSSLCDPETS-------ICQNCQHHTAGDFCERCALGY----YGIVKGLPN-DCQ 202
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C ++ + P + L +C C EG C +C P Y G
Sbjct: 203 QCACPLISSSNNFSPSCVAEGLD---------DYRCTACPRGYEGQYCERCAPGY---TG 250
Query: 350 KRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAY 395
+ CQ C+CDP+ S C+ +G C CRP C C +
Sbjct: 251 SPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKH 297
Score = 70.5 bits (165), Expect = 1e-10
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPD-------------CLSCNCDVSGSIGSTCD-DNGL 610
KC+C + G C+ C PG+Y+ C+ C C+ S+ CD + +
Sbjct: 114 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 170
Query: 611 C-HCKSNFDGAKCDTCREQFYNYPA-----CEECNCDPRGVTASFA-GCGSVPAGEL-C- 661
C +C+ + G C+ C +Y C++C C + +F+ C + + C
Sbjct: 171 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 230
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C +G+ C C P Y NP G C++C C+ G+L C+ +G C C+
Sbjct: 231 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLPV--PCDPVTGFCTCRPGA 287
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTEC 746
R+CD C R VF EC
Sbjct: 288 TGRKCDGCKHWHAREGWECVFCGDEC 313
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 1525 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 1574
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 1575 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 1618
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 1619 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 1673
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 1674 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 1729
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 1730 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 1789
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 1790 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 1824
Score = 54.0 bits (124), Expect = 1e-05
Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 30/156 (19%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRG----------CDDCNCNPLGVVGNQLQCEADSG 1449
C CP G +C+ C P + Q G C C CN G+ C+ ++
Sbjct: 115 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-----GHSSLCDPETS 169
Query: 1450 KCA-CRENVRGRVCDHCVPGHYAFP-----DCYQCTCNRHGTTYDVCDQNTAQ------C 1497
C C+ + G C+ C G+Y DC QC C ++ + A+ C
Sbjct: 170 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRC 229
Query: 1498 Y-CKTNVRGQACDTCKEEYFNLQDDNPDG-CTKCFC 1531
C GQ C+ C Y NP G C +C C
Sbjct: 230 TACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECEC 264
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 1525 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 1582
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 1583 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 1641
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 1642 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 1698
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 1699 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 1753
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 1754 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 1812
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 1813 IPFRGCI 1819
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1302 EFIEQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPC 1361
+F E+CA Y I C++ + S N+ + C+ + G + C C
Sbjct: 181 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE--GLDDYRCTA------C 232
Query: 1362 KPNVIGRTCSACRTGYYGFP-----NCRPCHC-PSTAI---CDD-NGMCICPKNVEGENC 1411
G+ C C GY G P +C+ C C P ++ CD G C C G C
Sbjct: 233 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 292
Query: 1412 DRCK 1415
D CK
Sbjct: 293 DGCK 296
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 917 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 973
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 974 RNGTISVRALDGPKASIVPSTHHSTSPPGY 1003
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 1497 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 1554
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 1555 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 1610
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 1611 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 1665
Score = 39.1 bits (87), Expect = 0.30
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 16/115 (13%)
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNY-----------TKDGCDHCNCNTGYSVGFMCN-ATGQ 2041
+C C G +G C+ C GF+ T C C CN G+S +C+ T
Sbjct: 114 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-GHS--SLCDPETSI 170
Query: 2042 CE-CLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLSALLANETMD 2095
C+ C G+ C+RC + I + +C C LI S + S E +D
Sbjct: 171 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 225
>M64283-1|AAA52699.1| 453|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 453
Score = 206 bits (503), Expect = 1e-51
Identities = 112/306 (36%), Positives = 148/306 (48%), Gaps = 13/306 (4%)
Query: 1634 PDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFSTLDGAPVTRDQFMHALVNISGL 1693
P V++ G N L H+ ++P G P T V E+ + DG P TR+ + AL I L
Sbjct: 11 PLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDTL 70
Query: 1694 YIRASYWEYSIETSLSNVVLEIGVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEG 1753
IRASY + E+ +S + +++ V G + A VE+C CP YRG SC+ C G
Sbjct: 71 LIRASYAQQPAESRVSGISMDVAVPEETGQD----PALEVEQCSCPPGYRGPSCQDCDTG 126
Query: 1754 HYRLPSGF----CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTP 1809
+ R PSG C C C+GHS+ C+ TG C C +T G CE C GY+GDA GTP
Sbjct: 127 YTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTP 186
Query: 1810 RDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLH 1869
+DC +C C + A +C L +G C PG+ G CE CA GYYG P
Sbjct: 187 QDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPC 246
Query: 1870 TGDYCKPCNCSGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCAP-GFYGDAIFSKN 1926
D P N +PQ S CD+ G C +C G C+ C P F+ A
Sbjct: 247 QRDSQVPGPIGCNCDPQGSVSSQCDAA-GQC-QCKAQVEGLTCSHCRPHHFHLSASNPDG 304
Query: 1927 CTACIC 1932
C C C
Sbjct: 305 CLPCFC 310
Score = 149 bits (361), Expect = 2e-34
Identities = 112/351 (31%), Positives = 148/351 (42%), Gaps = 45/351 (12%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPN------CRPCHCPS-TAICD-DNGMCI-CPKNVEG 1408
QC C P G +C C TGY P+ C C C + C+ + G C C + EG
Sbjct: 108 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 167
Query: 1409 ENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGNQLQ-CEADSG---KC-ACRENVRG 1459
C++C+P + D QRG C C C G C D+ C AC G
Sbjct: 168 PRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSG 226
Query: 1460 RVCDHCVPGHYAFPD----CYQ---------CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
R C+ C PG+Y P C + C C+ G+ CD QC CK V G
Sbjct: 227 RHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGL 285
Query: 1507 ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAIDEMVDWYPVD----VLIN 1562
C C+ +F+L NPDGC CFC G T +C+SS YT I + P D L+N
Sbjct: 286 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLIS--THFAPGDFQGFALVN 343
Query: 1563 --NTIELYPHEDVPELTNVTVLTVGLNDGVTNGKVAYFGAPEYYLGKRLTSYGGYLTYTV 1620
L V + L+ G N + Y+ PE Y G ++ YGG L YT+
Sbjct: 344 PQRNSRLTGEFTVEPVPEGAQLSFG-NFAQLGHESFYWQLPETYQGGKVAGYGGKLRYTL 402
Query: 1621 HYTTRGDGDAVAAPDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKLSEEEFS 1671
YT G ++ PDV I G N LV QP + P S ++ E +
Sbjct: 403 SYTAGPQGSPLSDPDVQITGNNIMLV---ASQPALQGPERRSYEIMFRELN 450
Score = 111 bits (268), Expect = 3e-23
Identities = 67/202 (33%), Positives = 88/202 (43%), Gaps = 32/202 (15%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP------TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C+C Y G +C C GY P TC+ C+C C+ +G C C+
Sbjct: 109 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHS---EACEPETGACQGCQHHT 165
Query: 523 GGPRCDQCLSGYYMQVL-GRERQCVPCNC--DPT-GSTSTSC--SADGK--CN-CLTNFG 573
GPRC+QC GYY G + C C C DP G + +C DG C+ C
Sbjct: 166 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 225
Query: 574 GAQCDQCSPGYYKYPD----C---------LSCNCDVSGSIGSTCDDNGLCHCKSNFDGA 620
G C++C+PGYY P C + CNCD GS+ S CD G C CK+ +G
Sbjct: 226 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 285
Query: 621 KCDTCREQFYNYPACEECNCDP 642
C CR ++ A C P
Sbjct: 286 TCSHCRPHHFHLSASNPDGCLP 307
Score = 102 bits (245), Expect = 2e-20
Identities = 72/226 (31%), Positives = 103/226 (45%), Gaps = 41/226 (18%)
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER-QCVPCNCDPTGSTST 558
+ +G +P++ +V QC C G+ GP C C +GY G C C+C S
Sbjct: 96 EETGQDPAL--EVE-QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSE 149
Query: 559 SCSAD-GKCN-CLTNFGGAQCDQCSPGYY------KYPDCLSCNC---DVSGSIGSTC-- 605
+C + G C C + G +C+QC PGYY DC C C +G TC
Sbjct: 150 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFL 209
Query: 606 --DDNGLCH-CKSNFDGAKCDTCREQFYNYPA----CEE---------CNCDPRGVTASF 649
D + C C G C+ C +Y P+ C+ CNCDP+G +S
Sbjct: 210 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS- 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
C + AG+ CQCK +V+G C+ C+P +++L NP GC C C
Sbjct: 269 -QCDA--AGQ-CQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 310
Score = 101 bits (242), Expect = 5e-20
Identities = 66/210 (31%), Positives = 91/210 (43%), Gaps = 38/210 (18%)
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPN------CKPCTCNLNGTEGEHCTPTDGLCP-C 427
E +C C P ++ P C C GY P+ C+ C+C+ E C P G C C
Sbjct: 105 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQGC 161
Query: 428 KYNYAGKSCEICEDGYYS-------PECKNCEC---NTVGSVSYVCDKLT-GDCTCKS-- 474
+++ G CE C+ GYY +C+ C C G ++ C T G TC +
Sbjct: 162 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 221
Query: 475 -KYSGRTCNQCQAGYYNYPT----CK---------PCNCDTSGTEPSICDDVSGQCICKA 520
+SGR C +C GYY P+ C+ CNCD G+ S C D +GQC CKA
Sbjct: 222 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC-DAAGQCQCKA 280
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
G C C ++ C+PC C
Sbjct: 281 QVEGLTCSHCRPHHFHLSASNPDGCLPCFC 310
Score = 86.2 bits (204), Expect = 2e-15
Identities = 65/222 (29%), Positives = 93/222 (41%), Gaps = 38/222 (17%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCE-CRPEF 385
+C G +C C Y R + L C+ C C H CE E+G C+ C+
Sbjct: 110 SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGHSEA--CEPETGACQGCQHHT 165
Query: 386 QPPDCSSCAYGYFDYP------NCKPCTCNLNGTEGE--H-C-TPTDG--LCP-CKYNYA 432
+ P C C GY+ +C+ C C + G+ H C TDG C C ++
Sbjct: 166 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 225
Query: 433 GKSCEICEDGYY-SPE----CKN---------CECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G+ CE C GYY +P C+ C C+ GSVS CD G C CK++ G
Sbjct: 226 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEG 284
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
TC+ C+ +++ P C P C ++ QC A
Sbjct: 285 LTCSHCRPHHFHLSASNPDGC-----LPCFCMGITQQCASSA 321
Score = 85.0 bits (201), Expect = 5e-15
Identities = 60/215 (27%), Positives = 91/215 (42%), Gaps = 29/215 (13%)
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDS 1942
P++ G ++ + C G +C C G+ ++ C C C A C+
Sbjct: 95 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA-CEP 153
Query: 1943 TTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPCNC------GIASESTQCDDD- 1991
TG C C+ G +C++C P ++G T C C C G A+ + D D
Sbjct: 154 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDG 213
Query: 1992 NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---------CNCNTGYSVGFMCNAT 2039
+ C C+ G +G+ C++CA G++ G C CNC+ SV C+A
Sbjct: 214 HPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAA 273
Query: 2040 GQCECLPGVIGEKCDRC-PERWVLIPQ--EGCLEC 2071
GQC+C V G C C P + L +GCL C
Sbjct: 274 GQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 308
Score = 78.2 bits (184), Expect = 5e-13
Identities = 69/248 (27%), Positives = 94/248 (37%), Gaps = 52/248 (20%)
Query: 244 DPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYD 303
DPA L + C C GP C C +G+ R +CE C+CH H+ C +
Sbjct: 101 DPA--LEVEQCSCPPGYRGPSCQDCDTGYT----RTPSGLYLGTCERCSCHGHSEAC--E 152
Query: 304 PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQC 363
PE G C CQH+TEG C +C+P YY +R D CQ C C
Sbjct: 153 PET----------------GACQGCQHHTEGPRCEQCQPGYYGD-AQRGTPQD-CQLCPC 194
Query: 364 --DPHF--STGNC---EEESGRCE-CRPEFQPPDCSSCAYGYFDYPN----CK------- 404
DP + C + C+ C P C CA GY+ P+ C+
Sbjct: 195 YGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 254
Query: 405 --PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
C C+ G+ C G C CK G +C C ++ N + G +
Sbjct: 255 PIGCNCDPQGSVSSQCDAA-GQCQCKAQVEGLTCSHCRPHHFHLSASNPD----GCLPCF 309
Query: 463 CDKLTGDC 470
C +T C
Sbjct: 310 CMGITQQC 317
Score = 77.4 bits (182), Expect = 9e-13
Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 141 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 189
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + + ++ +G C C G +C +C P YY P
Sbjct: 190 QLCPCYG-------DPAAGQAAHTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNP 240
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----- 398
+ + D P C CDP S + + +G+C+C+ + + CS C +F
Sbjct: 241 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSAS 300
Query: 399 DYPNCKPCTC 408
+ C PC C
Sbjct: 301 NPDGCLPCFC 310
Score = 74.9 bits (176), Expect = 5e-12
Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 565 KCNCLTNFGGAQCDQCSPGYYKYPDCL---SCN-CDVSGSIGSTCDDNGLCH-CKSNFDG 619
+C+C + G C C GY + P L +C C G + + G C C+ + +G
Sbjct: 108 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 167
Query: 620 AKCDTCREQFYNYPA------CEECNC--DPRGVTASFAGCGSVPAGELCQ-CKDRVQGR 670
+C+ C+ +Y C+ C C DP A+ C C GR
Sbjct: 168 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 227
Query: 671 ICNDCKPLYW-NLQEYNPF-------GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGE 722
C C P Y+ N + P G CNC+ G+++S C+ +GQC CK V
Sbjct: 228 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS--QCDA-AGQCQCKAQVEG 284
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDC 748
C C + L ++ GC C C
Sbjct: 285 LTCSHCRPHHFHLSASNPDGCLPCFC 310
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/196 (27%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYPA------CEECNCDPRGVTASFAGCGSVPAGELCQ-C 663
C C + G C C + P+ CE C+C P CQ C
Sbjct: 109 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE-------PETGACQGC 161
Query: 664 KDRVQGRICNDCKPLYW-NLQEYNPFGCEQCNCN---LAGTLNSLGACNTKSGQ-C-VCK 717
+ +G C C+P Y+ + Q P C+ C C AG +T C C
Sbjct: 162 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 221
Query: 718 QHVGERQCDQCLDGFYR--------LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHS 769
R C++C G+Y + + V G C+CD GS+ + CD GQC C +
Sbjct: 222 PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKA 280
Query: 770 RVEGRRCDQPIRAHYF 785
+VEG C R H+F
Sbjct: 281 QVEGLTCSH-CRPHHF 295
Score = 48.0 bits (109), Expect = 6e-04
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK
Sbjct: 230 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQ 281
Query: 1365 VIGRTCSACRTGYYGF-----PNCRPCHC 1388
V G TCS CR ++ C PC C
Sbjct: 282 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 310
Score = 41.9 bits (94), Expect = 0.042
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRL----PSGFCVPCQCNGHSDQC 1774
+CQC GL+C C H+ L P G C+PC C G + QC
Sbjct: 275 QCQCKAQVEGLTCSHCRPHHFHLSASNPDG-CLPCFCMGITQQC 317
Score = 37.1 bits (82), Expect = 1.2
Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 9/118 (7%)
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQCRCAKGVTGKQCDQCAA 2011
V G D P+ G + L C+C C D D G R G+ C++C+
Sbjct: 85 VSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSC 144
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATG-QCE-CLPGVIGEKCDRCPERWVLIPQEG 2067
+ C TG G + G +CE C PG G+ P+ L P G
Sbjct: 145 ------HGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG 196
>X84900-1|CAA59325.1| 1806|Homo sapiens alpha 3B chain of laminin-5
protein.
Length = 1806
Score = 204 bits (499), Expect = 4e-51
Identities = 260/1269 (20%), Positives = 504/1269 (39%), Gaps = 108/1269 (8%)
Query: 1901 CVNNTAGAACNLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEK 1957
C AG +C C+PG+Y D +++ C C C+ C +G CV C+ GE
Sbjct: 129 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEH 187
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNG--QCRCAKGVTGKQCDQCAAGFW 2014
C+RC ++G C C C + +T C + G +C C G TG QC++CA G++
Sbjct: 188 CERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF 247
Query: 2015 -NYTKDG--CDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
N K G C C+CN+ +G TG C + E D P E C +C
Sbjct: 248 GNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC-----INQEPKDSSPA-------EECDDC 295
Query: 2072 DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDI 2131
DSC L+ + + L + + S +++ ++ Q + LR ++ ++ I
Sbjct: 296 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-I 354
Query: 2132 GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVV 2191
S I+ LE +L + E + +A L + R + +E + V+
Sbjct: 355 SNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVI 414
Query: 2192 KHVADL-----ATGLELSQQPKVDSAL--TEARQIRDDIADKDLVPKKQQAEAVFLNTTT 2244
++V L T E + P D + EA+++ ++ +++ ++AEA +
Sbjct: 415 RNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQL 474
Query: 2245 QIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEE 2304
+ R+ + + + ++ S+ ++ E + KL D+ A A A
Sbjct: 475 LLNRIRTWQKTHQGENNGLAN-------SIRDSLNEYEAKLSDLRARLQEAAAQAKQANG 527
Query: 2305 LNTKNRLSKFGNKVNSVTKLNTAAMGDLIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXX 2364
LN +N + G V ++N+ D ++
Sbjct: 528 LNQENERA-LGAIQRQVKEINSL-QSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 585
Query: 2365 XXXXXXXXXXXXXTGELPQFEHLTS---EATHHATMLRRRADSLRELAERENNNSRTQHX 2421
EL + TS EA HA L+ A L E+ + + +
Sbjct: 586 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 645
Query: 2422 XXXXXXXXXXXQEINXXXXXXXXXXXXXXNV--TKLNRILDERVRPARERSSSLLADATK 2479
I + T + L + + S LL +A
Sbjct: 646 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 705
Query: 2480 AQHAVDQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRV 2538
Q + Q++ P L ++ L + D + ++ + A V
Sbjct: 706 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 765
Query: 2539 NATIGTTFSVMSHLGPELATSKDWAQTLPKLADEG-QKMTSNVESHLKNINDMEPQISSS 2597
T V+ L P + T + +E +K ++ ++ + + + P +
Sbjct: 766 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 825
Query: 2598 YHTVKMXXXXXXXXXXXXXXKLQKLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVD 2657
++ + ++++L++QAR A+++ V + F+ S ++ RLP+ ++
Sbjct: 826 IESINQQLLPLGNISD----NMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLE 881
Query: 2658 EMSTSTHVSAYFR---TKEKDG----FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVV 2710
++ T +S + + ++E G F++YLGN + S DY+ + + +G V
Sbjct: 882 DLKGYTSLSLFLQRPNSRENGGTENMFVMYLGN-------KDASRDYIGMAVVDGQLTCV 934
Query: 2711 MDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA 2769
++GD A + +D+++ + + ++DR+ +R+ R + G + +
Sbjct: 935 YNLGDRE------AELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETP 988
Query: 2770 ---DLPGH--HTIFNLDKEKSKLYVGGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLW 2823
D+ G +T+ NLD E YVGG P D KL +SFP ++G IE + + + L+
Sbjct: 989 GVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLY 1048
Query: 2824 NFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAP 2882
NF L + + Y F+G GYA + + + P Q + +T
Sbjct: 1049 NFKKTFNLNTTEVEPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVD 1104
Query: 2883 NGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAK 2942
GL++ G F SL ++DG++ ++ L N+E G A N+G+ H + + +
Sbjct: 1105 RGLLFFAENGDRFISLNIEDGKLMVRYKL-NSELPKERGVGDAINNGRDHSIQIKIGKLQ 1163
Query: 2943 CSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGI---LQVPDRGFDGCMRQISINGVN 2999
+ ++ +V ++ ++ T GG I + F GCM+ +
Sbjct: 1164 KRMWINVDV---QNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGV 1220
Query: 3000 LDLSENLESIGMAYGC----QFASLVSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPN 3052
+ L+ +++G+ C + SF+ L F D+ +++ Q + F+T +P+
Sbjct: 1221 VRLN---DTVGVTKKCSEDWKLVRSASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPS 1276
Query: 3053 GLLFVYVSRTQTAIMPDSISLSLVNG--KLVVVSQREQLDTGLNTYNDSQWHVLTVTHNT 3110
G+L + + T+ ++ ++L +G +L + TY D H ++V +
Sbjct: 1277 GILLDHQTWTR------NLQVTLEDGYIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDN 1330
Query: 3111 SALKLVVDD 3119
S L+L++DD
Sbjct: 1331 SGLRLLIDD 1339
Score = 203 bits (495), Expect = 1e-50
Identities = 115/299 (38%), Positives = 163/299 (54%), Gaps = 27/299 (9%)
Query: 1608 RLTSYGGYLTYTVH-YTTRGDGDAVAA-PDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKL 1665
+++SYGGYLTY + GD + PDV + G + +++ P V +
Sbjct: 1 KVSSYGGYLTYQAKSFALPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHV 60
Query: 1666 SEEEFSTLDG-APVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDE 1724
E F APV+R++ M L ++ + I+ Y+ + +LS V LE D G
Sbjct: 61 VEGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSG-- 118
Query: 1725 LVVRRATSVEECQCPRAYRGLSCEQCAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGI 1780
R A +VE C CP AY G SC+ C+ G+YR L +G CVPC CNGHS+QC +GI
Sbjct: 119 ---RIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGI 175
Query: 1781 CLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS 1840
C+NC NT G+HCE C GY+G+A G+ R ACP P+ +N+FA C + NG +
Sbjct: 176 CVNCQHNTAGEHCERCQEGYYGNAVHGSCR-----ACPCPH-TNSFATGCVV--NGGDVR 227
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
C+C+ GY G +CE CA GY+G P+ G C+PC+C+ N GSC + GDC+
Sbjct: 228 CSCKAGYTGTQCERCAPGYFGNPQ----KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 279
Score = 114 bits (275), Expect = 5e-24
Identities = 61/178 (34%), Positives = 83/178 (46%), Gaps = 18/178 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C P Y G C+ C+ GYY + L+TG C PCNC+G+ N C +G C+
Sbjct: 127 CACPPAYAGDSCQGCSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVN 178
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG--MADCDSTTG--TCVCRPGVIGE 1956
C +NTAG C C G+YG+A+ +C AC C C G C C+ G G
Sbjct: 179 CQHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 237
Query: 1957 KCDRCAPDHWG--LNTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
+C+RCAP ++G G C PC+C + C G C ++CD C
Sbjct: 238 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 295
Score = 107 bits (257), Expect = 7e-22
Identities = 57/174 (32%), Positives = 81/174 (46%), Gaps = 23/174 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C C Y+G +C C GYY Y C PCNC+ + C D SG C+ C+
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 183
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQ 579
G C++C GYY + C C C T S +T C +G +C+C + G QC++
Sbjct: 184 AGEHCERCQEGYYGNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 241
Query: 580 CSPGYYKYP-----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C+PGY+ P C C+C+ +G +GS G C K + +CD C
Sbjct: 242 CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 295
Score = 104 bits (249), Expect = 7e-21
Identities = 57/173 (32%), Positives = 84/173 (48%), Gaps = 25/173 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNY 431
C C P + C C+ GY+ D+ C PC CN + + C G+C C++N
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 183
Query: 432 AGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQ 485
AG+ CE C++GYY C+ C C S + C GD C+CK+ Y+G C +C
Sbjct: 184 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 243
Query: 486 AGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
GY+ P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 244 PGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 295
Score = 104 bits (249), Expect = 7e-21
Identities = 89/363 (24%), Positives = 160/363 (44%), Gaps = 24/363 (6%)
Query: 3309 RFGSRNVSRIEYAKLPGRQLEG-FDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
+FG S + + KLP L+ + +T +G ++F+ + KN F+A ++
Sbjct: 1461 QFGDIPTSHLLF-KLPQELLKPRSQFAVDMQTTSSRG-LVFHTGT---KN--SFMALYLS 1513
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPL 3427
+L + G+ I S ND WHTV +G G+L VD E S+ N+ +
Sbjct: 1514 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 1573
Query: 3428 SLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN-I 3486
S+ P Y G + + + N F+GCLK ++ + + ++ C+ +
Sbjct: 1574 SIRAPVYLGS--PPSGKPKSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 1628
Query: 3487 EDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK-DYMVLELL 3545
E G+YF + ++ L + +G E + +RPR+ TG+L+ + + ++ + L
Sbjct: 1629 EKGIYF----SEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1684
Query: 3546 DSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFS-KPGIGA 3604
+V A++++G G + ++ K LCDG WH + D S G
Sbjct: 1685 AGKVTASMDSGAG--GTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIP 1742
Query: 3605 YTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRG-AHVG 3663
+ T L++GG + +R + + F GC+RNI V PV V + +G +
Sbjct: 1743 FPPASTQEPLHLGGAPANLTTLR-IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 1801
Query: 3664 VCP 3666
CP
Sbjct: 1802 GCP 1804
Score = 97.9 bits (233), Expect = 6e-19
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 40/203 (19%)
Query: 249 LNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDE 308
L + +C C G C C G+ +R + C PCNC+ H+ +C
Sbjct: 122 LAVEICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------- 170
Query: 309 KRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPH-- 366
+G G C+NCQHNT G +C +C+ Y YG C+ C C PH
Sbjct: 171 -----------DGSGICVNCQHNTAGEHCERCQEGY---YGNAVH--GSCRACPC-PHTN 213
Query: 367 -FSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHC 418
F+TG C G RC C+ + C CA GYF P +C+PC+CN NG G C
Sbjct: 214 SFATG-CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-C 271
Query: 419 TPTDGLCPCKYNYAGKSCEICED 441
P G C + E C+D
Sbjct: 272 HPLTGDCINQEPKDSSPAEECDD 294
Score = 95.5 bits (227), Expect = 3e-18
Identities = 56/174 (32%), Positives = 81/174 (46%), Gaps = 15/174 (8%)
Query: 566 CNCLTNFGGAQCDQCSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFD 618
C C + G C CSPGYY+ Y C+ CNC+ G D +G+C +C+ N
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTA 184
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFA-GCGSVPAGEL-CQCKDRVQGRICNDCK 676
G C+ C+E +Y C P T SFA GC V G++ C CK G C C
Sbjct: 185 GEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC-VVNGGDVRCSCKAGYTGTQCERCA 243
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
P Y+ + C+ C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 244 PGYFGNPQKFGGSCQPCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 294
Score = 93.5 bits (222), Expect = 1e-17
Identities = 74/261 (28%), Positives = 110/261 (42%), Gaps = 26/261 (9%)
Query: 1947 CVCRPGVIGEKCDRCAP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
C C P G+ C C+P DH GL TG C PCNC S QC D +G C C
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN--GHSNQCQDGSGICVNCQHNT 183
Query: 2002 TGKQCDQCAAGFW-NYTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCDRCP 2057
G+ C++C G++ N C C C S C G +C C G G +C+RC
Sbjct: 184 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 243
Query: 2058 ERWVLIPQE---GCLECDSCTDALIFSVEDLSALLAN-ETMDFK-----DKADSFFTTQR 2108
+ PQ+ C C ++ + S L+ N E D D DS T
Sbjct: 244 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMT-L 302
Query: 2109 LNYISNQTELLRPKVAQLKTVDIGE-VTSSIKTLETSAKNL---LRSAEFAATDSDKQIS 2164
LN ++ E LR +QL+ + + ++ +ET AK+L L + A ++ +I
Sbjct: 303 LNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIE 362
Query: 2165 RAAKLAEDAERTLAAVRESAR 2185
+ D + ++E A+
Sbjct: 363 GLERELTDLNQEFETLQEKAQ 383
Score = 91.9 bits (218), Expect = 4e-17
Identities = 52/173 (30%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 424 LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
+C C YAG SC+ C GY Y+ C C CN S C +G C C+
Sbjct: 126 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHN 182
Query: 476 YSGRTCNQCQAGYYN---YPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQC 530
+G C +CQ GYY + +C+ C C + + + C G +C CKAG+ G +C++C
Sbjct: 183 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 242
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC---NCLTNFGGAQCDQC 580
GY+ C PC+C+ G + G C + +CD C
Sbjct: 243 APGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 295
Score = 87.0 bits (206), Expect = 1e-15
Identities = 51/180 (28%), Positives = 71/180 (39%), Gaps = 18/180 (10%)
Query: 1359 CPCKPNVIGRTCSACRTGYY----GF--PNCRPCHCP--STAICDDNGMCI-CPKNVEGE 1409
C C P G +C C GYY G C PC+C S D +G+C+ C N GE
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 186
Query: 1410 NCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+C+RC+ + V C C C +C+C+ G C+ C PG+
Sbjct: 187 HCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 246
Query: 1470 YAFP-----DCYQCTCNRHGTTYDVCDQNTAQCY---CKTNVRGQACDTCKEEYFNLQDD 1521
+ P C C+CN +G C T C K + + CD C L +D
Sbjct: 247 FGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLND 305
Score = 74.5 bits (175), Expect = 6e-12
Identities = 43/142 (30%), Positives = 56/142 (39%), Gaps = 14/142 (9%)
Query: 1399 MCICPKNVEGENCDRCKP--YTFNFDVQRG-CDDCNCNPLGVVGNQLQCEADSGKCA-CR 1454
+C CP G++C C P Y + + G C CNCN G+ QC+ SG C C+
Sbjct: 126 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNCQ 180
Query: 1455 ENVRGRVCDHCVPGHYA---FPDCYQCTCNRHGTTYDVCDQN--TAQCYCKTNVRGQACD 1509
N G C+ C G+Y C C C + C N +C CK G C+
Sbjct: 181 HNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 240
Query: 1510 TCKEEYFNLQDDNPDGCTKCFC 1531
C YF C C C
Sbjct: 241 RCAPGYFGNPQKFGGSCQPCSC 262
Score = 65.7 bits (153), Expect = 3e-09
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 160 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 206
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + +NG G +C +C+ G C +C P Y +G
Sbjct: 207 CPC----------PHTNSFATGCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 249
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 250 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 298
Score = 63.3 bits (147), Expect = 2e-08
Identities = 44/138 (31%), Positives = 59/138 (42%), Gaps = 14/138 (10%)
Query: 647 ASFAGCGSVP-AGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSL 704
AS G G + A E+C C G C C P Y+ + G C CNCN G N
Sbjct: 112 ASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ- 168
Query: 705 GACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG-CTECDCDIGGSIDNNCDKTT 762
C SG CV C+ + C++C +G+Y N V G C C C S C
Sbjct: 169 --CQDGSGICVNCQHNTAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNG 223
Query: 763 G--QCHCHSRVEGRRCDQ 778
G +C C + G +C++
Sbjct: 224 GDVRCSCKAGYTGTQCER 241
Score = 56.0 bits (129), Expect = 2e-06
Identities = 34/157 (21%), Positives = 54/157 (34%), Gaps = 5/157 (3%)
Query: 610 LCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C C + G C C +Y ++ C P C +G C+
Sbjct: 126 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQD-GSGICVNCQHNTA 184
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQC 728
G C C+ Y+ + C C C + + N +C CK QC++C
Sbjct: 185 GEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 242
Query: 729 LDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
G++ C C C+ G + +C TG C
Sbjct: 243 APGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDC 278
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCN--GHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P F C PC CN G C TG C+N D++
Sbjct: 228 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 287
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 288 PAEECDDCDS 297
Score = 50.8 bits (116), Expect = 9e-05
Identities = 60/292 (20%), Positives = 118/292 (40%), Gaps = 30/292 (10%)
Query: 2725 RVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEK 2784
R+ + D +W+ V+ G + +L + D + ++E LPG+ TI +
Sbjct: 1529 RIKSKEKCNDGKWHTVVFGHDGEKGRLVV--------DGLRAREGSLPGNSTI----SIR 1576
Query: 2785 SKLYVGGVPSDAKLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQ 2844
+ +Y+G PS K + + +F G ++ + P+ + ++ + S
Sbjct: 1577 APVYLGSPPS-GKPKSLPTNSFVGCLKNFQLDSKPL----YTPSSSFG-------VSSCL 1624
Query: 2845 SGPQE---YRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
GP E Y + G+ +A L P+ V LI++ + G + ++
Sbjct: 1625 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1684
Query: 2902 DGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSA 2961
G+V + G V ++ DG+WH + L +D + P
Sbjct: 1685 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 1744
Query: 2962 DIPSLDTMNFGG--NNKGILQVPD-RGFDGCMRQISINGVNLDLSENLESIG 3010
+ + ++ GG N L++P + F GC+R I +N + + ++E LE G
Sbjct: 1745 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 1796
Score = 50.0 bits (114), Expect = 2e-04
Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 9/309 (2%)
Query: 2866 LTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
L P+S Q + +T + GL++ G F +L + GR L +LG + + +
Sbjct: 1479 LKPRS-QFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGR--LVFALGTDGKKLRIKSKEK 1535
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKG-ILQVPDR 2984
NDGKWH + K L VD + S ++ I + G G +P
Sbjct: 1536 CNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTN 1595
Query: 2985 GFDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTL 3044
F GC++ ++ L + + G + F+ ++ P+ L
Sbjct: 1596 SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKL 1655
Query: 3045 KFKTAKPNGL--LFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-TGLNTYNDSQW 3101
F + +P L + +++ + + V + + T + D QW
Sbjct: 1656 VF-SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQW 1714
Query: 3102 HVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFT 3161
H + VT L L +D ++ P P L +GG P + + + F
Sbjct: 1715 HSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGA-PANLTTLRIPVWKSFF 1773
Query: 3162 GCIGDATIN 3170
GC+ + +N
Sbjct: 1774 GCLRNIHVN 1782
Score = 48.4 bits (110), Expect = 5e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 16/122 (13%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGG--QCPCKPN 1364
C + + + C+E + + + R C C S C GG +C CK
Sbjct: 176 CVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 233
Query: 1365 VIGRTCSACRTGYYGFP-----NCRPCHCPST---AICDD-NGMCIC--PKNVE-GENCD 1412
G C C GY+G P +C+PC C S C G CI PK+ E CD
Sbjct: 234 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECD 293
Query: 1413 RC 1414
C
Sbjct: 294 DC 295
>X85108-1|CAA59429.1| 1331|Homo sapiens alpha3b subunit of laminin 5
protein.
Length = 1331
Score = 202 bits (493), Expect = 2e-50
Identities = 114/299 (38%), Positives = 163/299 (54%), Gaps = 27/299 (9%)
Query: 1608 RLTSYGGYLTYTVH-YTTRGDGDAVAA-PDVIIAGPNGYLVHNSVEQPPVGMPWTHSVKL 1665
+++SYGGYLTY + GD + PDV + G + +++ P V +
Sbjct: 1 KVSSYGGYLTYQAKSFALPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHV 60
Query: 1666 SEEEFSTLDG-APVTRDQFMHALVNISGLYIRASYWEYSIETSLSNVVLEIGVDYYMGDE 1724
E F APV+R++ M L ++ + I+ Y+ + +LS V LE D G
Sbjct: 61 VEGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSG-- 118
Query: 1725 LVVRRATSVEECQCPRAYRGLSCEQCAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGI 1780
R A +VE C CP AY G SC+ C+ G+YR L +G CVPC CNGHS+QC +GI
Sbjct: 119 ---RIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGI 175
Query: 1781 CLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS 1840
C+NC NT G+HCE C GY+G+A G+ R ACP P+ +N+F + C + NG +
Sbjct: 176 CVNCQHNTAGEHCERCQEGYYGNAVHGSCR-----ACPCPH-TNSFGMCCVV--NGGDVR 227
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
C+C+ GY G +CE CA GY+G P+ G C+PC+C+ N GSC + GDC+
Sbjct: 228 CSCKAGYTGTQCERCAPGYFGNPQ----KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 279
Score = 192 bits (469), Expect = 2e-47
Identities = 246/1211 (20%), Positives = 475/1211 (39%), Gaps = 100/1211 (8%)
Query: 1901 CVNNTAGAACNLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEK 1957
C AG +C C+PG+Y D +++ C C C+ C +G CV C+ GE
Sbjct: 129 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEH 187
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG---QCRCAKGVTGKQCDQCAAGFW 2014
C+RC ++G C C C + C NG +C C G TG QC++CA G++
Sbjct: 188 CERCQEGYYGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYF 247
Query: 2015 -NYTKDG--CDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
N K G C C+CN+ +G TG C + E D P E C +C
Sbjct: 248 GNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC-----INQEPKDSSPA-------EECDDC 295
Query: 2072 DSCTDALIFSVEDLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDI 2131
DSC L+ + + L + + S +++ ++ Q + LR ++ ++ I
Sbjct: 296 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-I 354
Query: 2132 GEVTSSIKTLETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVV 2191
S I+ LE +L + E + +A L + R + +E + V+
Sbjct: 355 SNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVI 414
Query: 2192 KHVADL-----ATGLELSQQPKVDSAL--TEARQIRDDIADKDLVPKKQQAEAVFLNTTT 2244
++V L T E + P D + EA+++ ++ +++ ++AEA +
Sbjct: 415 RNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQL 474
Query: 2245 QIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEE 2304
+ R+ + + + ++ S+ ++ E + KL D+ A A A
Sbjct: 475 LLNRIRTWQKTHQGENNGLAN-------SIRDSLNEYEAKLSDLRARLQEAAAQAKQANG 527
Query: 2305 LNTKNRLSKFGNKVNSVTKLNTAAMGDLIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXX 2364
LN +N + G V ++N+ D ++
Sbjct: 528 LNQENERA-LGAIQRQVKEINSL-QSDFTKYLTTADSSLLQTNIALQLKEKSQKEYEKLA 585
Query: 2365 XXXXXXXXXXXXXTGELPQFEHLTS---EATHHATMLRRRADSLRELAERENNNSRTQHX 2421
EL + TS EA HA L+ A L E+ + + +
Sbjct: 586 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 645
Query: 2422 XXXXXXXXXXXQEINXXXXXXXXXXXXXXNV--TKLNRILDERVRPARERSSSLLADATK 2479
I + T + L + + S LL +A
Sbjct: 646 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 705
Query: 2480 AQHAVDQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRV 2538
Q + Q++ P L ++ L + D + ++ + A V
Sbjct: 706 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 765
Query: 2539 NATIGTTFSVMSHLGPELATSKDWAQTLPKLADEG-QKMTSNVESHLKNINDMEPQISSS 2597
T V+ L P + T + +E +K ++ ++ + + + P +
Sbjct: 766 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 825
Query: 2598 YHTVKMXXXXXXXXXXXXXXKLQKLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVD 2657
++ + ++ +L++QAR A+++ V + F+ S ++ RLP+ ++
Sbjct: 826 IESINQQLLPLGNISD----NMDRILELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLE 881
Query: 2658 EMSTSTHVSAYFR---TKEKDG----FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVV 2710
++ T +S + + ++E G F++YLGN + S DY+ + + +G V
Sbjct: 882 DLKGYTSLSLFLQRPNSRENGGTENMFVMYLGN-------KDASRDYIGMAVVDGQLTCV 934
Query: 2711 MDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA 2769
++GD A + +D+++ + + ++DR+ +R+ R + G + +
Sbjct: 935 YNLGDRE------AELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETP 988
Query: 2770 ---DLPGH--HTIFNLDKEKSKLYVGGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLW 2823
D+ G +T+ NLD E YVGG P D KL +SFP ++G IE + + + L+
Sbjct: 989 GVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLY 1048
Query: 2824 NFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAP 2882
NF L + + + Y F+G GYA + + + P Q + +T
Sbjct: 1049 NFKKTFNLNTTEVQPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVD 1104
Query: 2883 NGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAK 2942
GL++ G F SL ++DG++ ++ L N+E G A N+G+ H + + +
Sbjct: 1105 RGLLFFAENGDRFISLNIEDGKLMVRYKL-NSELPKERGVGAAINNGRDHSIQIKIGKLQ 1163
Query: 2943 CSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGI---LQVPDRGFDGCMRQISINGVN 2999
+ ++ +V ++ ++ T GG I + F GCM+ +
Sbjct: 1164 KRMWINVDV---QNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGV 1220
Query: 3000 LDLSENLESIGMAYGC----QFASLVSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPN 3052
+ L+ +++G+ C + SF+ L F D+ +++ Q + F+T +P+
Sbjct: 1221 VRLN---DTVGVTKKCSEDWKLVRSASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPS 1276
Query: 3053 GLLFVYVSRTQ 3063
+L + + T+
Sbjct: 1277 AILLDHQTWTR 1287
Score = 118 bits (285), Expect = 3e-25
Identities = 64/179 (35%), Positives = 87/179 (48%), Gaps = 20/179 (11%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C P Y G C+ C+ GYY + L+TG C PCNC+G+ N C +G C+
Sbjct: 127 CACPPAYAGDSCQGCSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVN 178
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACIC---DEFGMADCDSTTG--TCVCRPGVIG 1955
C +NTAG C C G+YG+A+ +C AC C + FGM C G C C+ G G
Sbjct: 179 CQHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFGMC-CVVNGGDVRCSCKAGYTG 236
Query: 1956 EKCDRCAPDHWG--LNTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
+C+RCAP ++G G C PC+C + C G C ++CD C
Sbjct: 237 TQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 295
Score = 105 bits (251), Expect = 4e-21
Identities = 57/173 (32%), Positives = 83/173 (47%), Gaps = 25/173 (14%)
Query: 379 CECRPEFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNY 431
C C P + C C+ GY+ D+ C PC CN + + C G+C C++N
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 183
Query: 432 AGKSCEICEDGYYS----PECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQ 485
AG+ CE C++GYY C+ C C S C GD C+CK+ Y+G C +C
Sbjct: 184 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCA 243
Query: 486 AGYYNYP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
GY+ P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 244 PGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 295
Score = 104 bits (249), Expect = 7e-21
Identities = 56/174 (32%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 470 CTCKSKYSGRTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGF 522
C C Y+G +C C GYY Y C PCNC+ + C D SG C+ C+
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 183
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQ 579
G C++C GYY + C C C T S C +G +C+C + G QC++
Sbjct: 184 AGEHCERCQEGYYGNAV--HGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCER 241
Query: 580 CSPGYYKYP-----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C+PGY+ P C C+C+ +G +GS G C K + +CD C
Sbjct: 242 CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 295
Score = 97.9 bits (233), Expect = 6e-19
Identities = 54/173 (31%), Positives = 79/173 (45%), Gaps = 13/173 (7%)
Query: 566 CNCLTNFGGAQCDQCSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFD 618
C C + G C CSPGYY+ Y C+ CNC+ G D +G+C +C+ N
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTA 184
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGEL-CQCKDRVQGRICNDCKP 677
G C+ C+E +Y C P T SF C V G++ C CK G C C P
Sbjct: 185 GEHCERCQEGYYGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAP 244
Query: 678 LYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
Y+ + C+ C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 245 GYFGNPQKFGGSCQPCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 294
Score = 97.5 bits (232), Expect = 8e-19
Identities = 75/261 (28%), Positives = 111/261 (42%), Gaps = 26/261 (9%)
Query: 1947 CVCRPGVIGEKCDRCAP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
C C P G+ C C+P DH GL TG C PCNC S QC D +G C C
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN--GHSNQCQDGSGICVNCQHNT 183
Query: 2002 TGKQCDQCAAGFW-NYTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCDRCP 2057
G+ C++C G++ N C C C S G C G +C C G G +C+RC
Sbjct: 184 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCA 243
Query: 2058 ERWVLIPQE---GCLECDSCTDALIFSVEDLSALLAN-ETMDFK-----DKADSFFTTQR 2108
+ PQ+ C C ++ + S L+ N E D D DS T
Sbjct: 244 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMT-L 302
Query: 2109 LNYISNQTELLRPKVAQLKTVDIGE-VTSSIKTLETSAKNL---LRSAEFAATDSDKQIS 2164
LN ++ E LR +QL+ + + ++ +ET AK+L L + A ++ +I
Sbjct: 303 LNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIE 362
Query: 2165 RAAKLAEDAERTLAAVRESAR 2185
+ D + ++E A+
Sbjct: 363 GLERELTDLNQEFETLQEKAQ 383
Score = 96.7 bits (230), Expect = 1e-18
Identities = 62/201 (30%), Positives = 84/201 (41%), Gaps = 36/201 (17%)
Query: 249 LNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDE 308
L + +C C G C C G+ +R + C PCNC+ H+ +C
Sbjct: 122 LAVEICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------- 170
Query: 309 KRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFS 368
+G G C+NCQHNT G +C +C+ Y YG C+ C C S
Sbjct: 171 -----------DGSGICVNCQHNTAGEHCERCQEGY---YGNAVH--GSCRACPCPHTNS 214
Query: 369 TGNCEEESG---RCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEGEHCTP 420
G C +G RC C+ + C CA GYF P +C+PC+CN NG G C P
Sbjct: 215 FGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHP 273
Query: 421 TDGLCPCKYNYAGKSCEICED 441
G C + E C+D
Sbjct: 274 LTGDCINQEPKDSSPAEECDD 294
Score = 91.9 bits (218), Expect = 4e-17
Identities = 53/174 (30%), Positives = 78/174 (44%), Gaps = 21/174 (12%)
Query: 424 LCPCKYNYAGKSCEICEDGY-------YSPECKNCECNTVGSVSYVCDKLTGDC-TCKSK 475
+C C YAG SC+ C GY Y+ C C CN S C +G C C+
Sbjct: 126 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHN 182
Query: 476 YSGRTCNQCQAGYYN---YPTCKPCNCDTSGTEPSICDDVSG---QCICKAGFGGPRCDQ 529
+G C +CQ GYY + +C+ C C + + +C V+G +C CKAG+ G +C++
Sbjct: 183 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSF-GMCCVVNGGDVRCSCKAGYTGTQCER 241
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC---NCLTNFGGAQCDQC 580
C GY+ C PC+C+ G + G C + +CD C
Sbjct: 242 CAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 295
Score = 88.2 bits (209), Expect = 5e-16
Identities = 52/180 (28%), Positives = 72/180 (40%), Gaps = 18/180 (10%)
Query: 1359 CPCKPNVIGRTCSACRTGYY----GF--PNCRPCHCP--STAICDDNGMCI-CPKNVEGE 1409
C C P G +C C GYY G C PC+C S D +G+C+ C N GE
Sbjct: 127 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 186
Query: 1410 NCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
+C+RC+ + V C C C G +C+C+ G C+ C PG+
Sbjct: 187 HCERCQEGYYGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGY 246
Query: 1470 YAFP-----DCYQCTCNRHGTTYDVCDQNTAQCY---CKTNVRGQACDTCKEEYFNLQDD 1521
+ P C C+CN +G C T C K + + CD C L +D
Sbjct: 247 FGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLND 305
Score = 76.2 bits (179), Expect = 2e-12
Identities = 43/143 (30%), Positives = 59/143 (41%), Gaps = 16/143 (11%)
Query: 1399 MCICPKNVEGENCDRCKP--YTFNFDVQRG-CDDCNCNPLGVVGNQLQCEADSGKCA-CR 1454
+C CP G++C C P Y + + G C CNCN G+ QC+ SG C C+
Sbjct: 126 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNCQ 180
Query: 1455 ENVRGRVCDHCVPGHYA---FPDCYQCTCNRHGTTYDVC---DQNTAQCYCKTNVRGQAC 1508
N G C+ C G+Y C C C H ++ +C + +C CK G C
Sbjct: 181 HNTAGEHCERCQEGYYGNAVHGSCRACPCP-HTNSFGMCCVVNGGDVRCSCKAGYTGTQC 239
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFC 1531
+ C YF C C C
Sbjct: 240 ERCAPGYFGNPQKFGGSCQPCSC 262
Score = 66.1 bits (154), Expect = 2e-09
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 160 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 206
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + + +NG G +C +C+ G C +C P Y +G
Sbjct: 207 CPC----------PHTNSFGMCCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 249
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 250 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 298
Score = 61.7 bits (143), Expect = 5e-08
Identities = 44/138 (31%), Positives = 59/138 (42%), Gaps = 14/138 (10%)
Query: 647 ASFAGCGSVP-AGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSL 704
AS G G + A E+C C G C C P Y+ + G C CNCN G N
Sbjct: 112 ASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ- 168
Query: 705 GACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG-CTECDCDIGGSIDNNCDKTT 762
C SG CV C+ + C++C +G+Y N V G C C C S C
Sbjct: 169 --CQDGSGICVNCQHNTAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFGMCCVVNG 223
Query: 763 G--QCHCHSRVEGRRCDQ 778
G +C C + G +C++
Sbjct: 224 GDVRCSCKAGYTGTQCER 241
Score = 58.0 bits (134), Expect = 6e-07
Identities = 38/160 (23%), Positives = 57/160 (35%), Gaps = 11/160 (6%)
Query: 610 LCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
+C C + G C C +Y ++ C P C +G C+
Sbjct: 126 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQD-GSGICVNCQHNTA 184
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG---QCVCKQHVGERQC 725
G C C+ Y+ + C C C NS G C +G +C CK QC
Sbjct: 185 GEHCERCQEGYYGNAVHG--SCRACPCPHT---NSFGMCCVVNGGDVRCSCKAGYTGTQC 239
Query: 726 DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
++C G++ C C C+ G + +C TG C
Sbjct: 240 ERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDC 278
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGF---CVPCQCN--GHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P F C PC CN G C TG C+N D++
Sbjct: 228 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 287
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 288 PAEECDDCDS 297
Score = 48.4 bits (110), Expect = 5e-04
Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 16/122 (13%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGG--QCPCKPN 1364
C + + + C+E + + + R C C S + C GG +C CK
Sbjct: 176 CVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAG 233
Query: 1365 VIGRTCSACRTGYYGFP-----NCRPCHCPST---AICDD-NGMCIC--PKNVE-GENCD 1412
G C C GY+G P +C+PC C S C G CI PK+ E CD
Sbjct: 234 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECD 293
Query: 1413 RC 1414
C
Sbjct: 294 DC 295
>AF278532-1|AAG30822.1| 628|Homo sapiens beta-netrin protein.
Length = 628
Score = 202 bits (492), Expect = 3e-50
Identities = 127/401 (31%), Positives = 188/401 (46%), Gaps = 52/401 (12%)
Query: 34 CDICDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVF 89
CD C+A H P D RTWWQS + + +DL EF+ ++
Sbjct: 77 CDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLI 131
Query: 90 VKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTE 149
V M SPRP VL++S D+GKT+KP++YF+ + C FG E + K + IC+++
Sbjct: 132 V-MFKSPRPAAMVLDRSQDFGKTWKPYKYFATN---CSATFGLED--DVVKKGA-ICTSK 184
Query: 150 YSKIVPLEDGEIPISLLND-RPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVA 208
YS P GE+ L+ + N Y S+ +QE + TN+R++LL+ ++
Sbjct: 185 YSSPFPCTGGEVIFKALSPPHDTENPY--SAKVQEQLKITNLRVQLLKRQSC-----PCQ 237
Query: 209 RQDPTVTRRYF--YSIKDISIGGRCMCNGHADTC------EPADPAGNLNIL--VCRCQH 258
R D ++F Y+I D + G C CNGHAD C P G +++ C C+H
Sbjct: 238 RNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKH 297
Query: 259 NTCGPQCNKCCSGFEQKKWRISQNWDRF--SCEPCNCHNHTTECTYDPEIDEKRLSLDIN 316
NT G C C + + W + C C C+ H C +D + E +
Sbjct: 298 NTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA------S 351
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST---GN-- 371
G GG C +CQHNTEG C +C+P +YR + + D C+PC C P S N
Sbjct: 352 GN-RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 372 --CEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
C+ +G C C+P C C GY+ + + C+PC C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 96.7 bits (230), Expect = 1e-18
Identities = 69/203 (33%), Positives = 96/203 (47%), Gaps = 42/203 (20%)
Query: 1716 GVDYYMGDELVVRRATSVEECQ-CPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC 1774
G + + + + + T+ CQ C Y E A+G P+ C C+CNGH+D C
Sbjct: 284 GTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWE-AADGKTGAPNE-CRACKCNGHADTC 341
Query: 1775 --DVNT---------GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICAC-PMP 1820
DVN G+C +C NT G +C+ C G++ D P C C+C P+
Sbjct: 342 HFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVG 401
Query: 1821 ---YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDY-CKP 1876
P+N+ CD S NG C C+PG G RC+ C GY+G GDY C+P
Sbjct: 402 SAVLPANSVTF-CDPS-NGD---CPCKPGVAGRRCDRCMVGYWGF--------GDYGCRP 448
Query: 1877 CNCSGNINPQDPGSCDSINGDCL 1899
C+C+ GSCD I GDC+
Sbjct: 449 CDCA--------GSCDPITGDCI 463
Score = 83.4 bits (197), Expect = 1e-14
Identities = 53/171 (30%), Positives = 76/171 (44%), Gaps = 34/171 (19%)
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS---------KNCTACICD----- 1933
PG+ ++G C+ C +NTAG+ C CAP Y D + C AC C+
Sbjct: 283 PGTFHMVHGKCM-CKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRACKCNGHADT 340
Query: 1934 -EFGM----ADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCGI- 1981
F + A + + G C C+ G+ C RC P + + C PC+C
Sbjct: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
Query: 1982 ------ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNC 2026
A+ T CD NG C C GV G++CD+C G+W + GC C+C
Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 82.6 bits (195), Expect = 2e-14
Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 33/182 (18%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP------------ACEECNCDPRGVTASF-----A 650
+G C CK N G+ C C + + P C C C+ T F
Sbjct: 290 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWE 349
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP-LYWNLQE--YNPFGCEQCNCNLAGTL----NS 703
G+ G C+ +G+ C CKP Y +L+ P C+ C+C+ G+ NS
Sbjct: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
+ C+ +G C CK V R+CD+C+ G++ +GC CDC GS CD TG
Sbjct: 410 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDC--AGS----CDPITG 460
Query: 764 QC 765
C
Sbjct: 461 DC 462
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/202 (29%), Positives = 85/202 (42%), Gaps = 47/202 (23%)
Query: 356 DVCQPCQ-CDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP------------N 402
D C P P + G G+C C+ C CA Y D P
Sbjct: 269 DQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNE 328
Query: 403 CKPCTCN---------LNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGYY-------- 444
C+ C CN +N E + G+C C++N G+ C+ C+ G+Y
Sbjct: 329 CRACKCNGHADTCHFDVNVWEASG-NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
Query: 445 SPE-CKNCECNTVGSVSY------VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CK 495
+P+ CK C C+ VGS CD GDC CK +GR C++C GY+ + C+
Sbjct: 388 APDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCR 447
Query: 496 PCNCDTSGTEPSICDDVSGQCI 517
PC+C S CD ++G CI
Sbjct: 448 PCDCAGS------CDPITGDCI 463
Score = 77.4 bits (182), Expect = 9e-13
Identities = 63/224 (28%), Positives = 88/224 (39%), Gaps = 45/224 (20%)
Query: 540 GRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP---------- 588
G QC+P + P + T GKC C N G+ C C+P Y P
Sbjct: 266 GHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGA 325
Query: 589 --DCLSCNC---------DVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY------ 630
+C +C C DV+ S G+C C+ N +G C C+ FY
Sbjct: 326 PNECRACKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRP 385
Query: 631 -NYP-ACEECNCDPRGVTASFAGCGSV--PAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
+ P AC+ C+C P G A + P+ C CK V GR C+ C YW +Y
Sbjct: 386 FSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY- 444
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
GC C+C G+C+ +G C+ H C + D
Sbjct: 445 --GCRPCDC--------AGSCDPITGDCI-SSHTDIDWCHEVPD 477
Score = 77.0 bits (181), Expect = 1e-12
Identities = 58/177 (32%), Positives = 75/177 (42%), Gaps = 41/177 (23%)
Query: 1357 GQCPCKPNVIGRTCSAC-----------RTGYYGFPN-CRPCHC---PSTAICDDN---- 1397
G+C CK N G C C G G PN CR C C T D N
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA 350
Query: 1398 ------GMC-ICPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLG---VVGNQL 1442
G+C C N EG+ C RCKP + F C C+C+P+G + N +
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 1443 Q-CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTYDVCDQNTAQC 1497
C+ +G C C+ V GR CD C+ G++ F D Y C C+ G+ CD T C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD-YGCRPCDCAGS----CDPITGDC 462
Score = 70.9 bits (166), Expect = 8e-11
Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 39/164 (23%)
Query: 423 GLCPCKYNYAGKSCEICEDGYY------------SP-ECKNCECNTVGSVSYVC------ 463
G C CK+N AG C+ C Y +P EC+ C+CN +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA 350
Query: 464 --DKLTGDCT-CKSKYSGRTCNQCQAGYY-------NYP-TCKPCNCDTSGT------EP 506
++ G C C+ G+ C +C+ G+Y + P CKPC+C G+
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 507 SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
+ CD +G C CK G G RCD+C+ GY+ G + C PC+C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFG-DYGCRPCDC 451
Score = 67.7 bits (158), Expect = 7e-10
Identities = 60/208 (28%), Positives = 79/208 (37%), Gaps = 38/208 (18%)
Query: 1384 RPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFN-----FDVQRG----CDDCNCNP 1434
RP P T +G C+C N G +C C P + D + G C C CN
Sbjct: 278 RPVKAPGTFHMV-HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNG 336
Query: 1435 ------LGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHY-------AFPD-CYQCT 1479
V + G C C+ N G+ C C PG Y + PD C C+
Sbjct: 337 HADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCS 396
Query: 1480 CNRHGT------TYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
C+ G+ + CD + C CK V G+ CD C Y+ D GC C C G
Sbjct: 397 CHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDCAG 453
Query: 1534 K----TTRCSSSYYTWAAIDEMVDWYPV 1557
T C SS+ E+ D+ PV
Sbjct: 454 SCDPITGDCISSHTDIDWCHEVPDFRPV 481
Score = 64.9 bits (151), Expect = 5e-09
Identities = 65/238 (27%), Positives = 96/238 (40%), Gaps = 35/238 (14%)
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
Y +D+ C CN + C P G P K A + + +C C+ N
Sbjct: 251 YAIYDFIVKGSCFCN---GHADQCIPVHGFRPVK---APGTFHMVHG-----KCM-CKHN 298
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPTCKPCNCDTSGTEPSICDDV 512
T GS C L D ++ G+T N+C+A N C+ D + E S +
Sbjct: 299 TAGSHCQHCAPLYNDRPWEAA-DGKTGAPNECRACKCN-GHADTCHFDVNVWEAS-GNRS 355
Query: 513 SGQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGS------TSTSCS- 561
G C C+ G C +C G+Y + C PC+C P GS + T C
Sbjct: 356 GGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDP 415
Query: 562 ADGKCNCLTNFGGAQCDQCSPGYYKYPD--CLSCNC-----DVSGSIGSTCDDNGLCH 612
++G C C G +CD+C GY+ + D C C+C ++G S+ D CH
Sbjct: 416 SNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWCH 473
Score = 63.7 bits (148), Expect = 1e-08
Identities = 34/73 (46%), Positives = 39/73 (53%), Gaps = 11/73 (15%)
Query: 1338 RPCLCDFMGSTELECN--TF----GGQCPCKPNVIGRTCSACRTGYYGFPN--CRPCHCP 1389
+PC C +GS L N TF G CPCKP V GR C C GY+GF + CRPC C
Sbjct: 393 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCA 452
Query: 1390 STAICDD-NGMCI 1401
+ CD G CI
Sbjct: 453 GS--CDPITGDCI 463
Score = 61.3 bits (142), Expect = 6e-08
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 32/160 (20%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDH----WGLNTGLG-----CTPCNCGIASESTQCDDD---- 1991
G C+C+ G C CAP + W G C C C +++ D +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA 350
Query: 1992 -----NGQCR-CAKGVTGKQCDQCAAGFWNYTK------DGCDHCNCNT-------GYSV 2032
G C C G+ C +C GF+ + D C C+C+ SV
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 2033 GFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECD 2072
F + G C C PGV G +CDRC + GC CD
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCD 450
Score = 60.1 bits (139), Expect = 1e-07
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 34/163 (20%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQ-------VLGRERQCVPCNCDPTGST-------- 556
V G+C+CK G C C Y + G +C C C+ T
Sbjct: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVW 348
Query: 557 -STSCSADGKC-NCLTNFGGAQCDQCSPGYYK-------YPD-CLSCNCDVSGSI----- 601
++ + G C +C N G C +C PG+Y+ PD C C+C GS
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
Query: 602 -GSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
+ CD NG C CK G +CD C ++ + C C+C
Sbjct: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 59.3 bits (137), Expect = 3e-07
Identities = 49/141 (34%), Positives = 56/141 (39%), Gaps = 23/141 (16%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEYN---PFGCEQCNCN-LAGT----LNSLGACN 708
C CK G C C PLY W + P C C CN A T +N A
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEASG 352
Query: 709 TKSGQ-CVCKQHVGERQ-CDQCLDGFYRLQTNDVFG---CTECDCDIGGS--IDNN---- 757
+SG C QH E Q C +C GFYR C C C GS + N
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 758 CDKTTGQCHCHSRVEGRRCDQ 778
CD + G C C V GRRCD+
Sbjct: 413 CDPSNGDCPCKPGVAGRRCDR 433
>AF297711-1|AAG53651.1| 628|Homo sapiens netrin 4 precursor
protein.
Length = 628
Score = 201 bits (490), Expect = 4e-50
Identities = 125/400 (31%), Positives = 187/400 (46%), Gaps = 50/400 (12%)
Query: 34 CDICDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVF 89
CD C+A H P D RTWWQS + + +DL EF+ ++
Sbjct: 77 CDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLI 131
Query: 90 VKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTE 149
V M SPRP VL++S D+GKT+KP++YF+ + C FG E + K + IC+++
Sbjct: 132 V-MFKSPRPAAMVLDRSQDFGKTWKPYKYFATN---CSATFGLED--DVVKKGA-ICTSK 184
Query: 150 YSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVAR 209
YS P GE+ L+ + +++ V QE + TN+R++LL+ ++ R
Sbjct: 185 YSSPFPCTGGEVIFKALSPPYDTENPYSAKV-QEQLKITNLRVQLLKRQSC-----PCQR 238
Query: 210 QDPTVTRRYF--YSIKDISIGGRCMCNGHADTC------EPADPAGNLNIL--VCRCQHN 259
D ++F Y+I D + G C CNGHAD C P G +++ C C+HN
Sbjct: 239 NDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHN 298
Query: 260 TCGPQCNKCCSGFEQKKWRISQNWDRF--SCEPCNCHNHTTECTYDPEIDEKRLSLDING 317
T G C C + + W + C C C+ H C +D + E +G
Sbjct: 299 TAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA------SG 352
Query: 318 RYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST---GN--- 371
GG C +CQHNTEG C +C+P +YR + + D C+PC C P S N
Sbjct: 353 N-RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVT 411
Query: 372 -CEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
C+ +G C C+P C C GY+ + + C+PC C
Sbjct: 412 FCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 99.5 bits (237), Expect = 2e-19
Identities = 61/176 (34%), Positives = 78/176 (44%), Gaps = 27/176 (15%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP-EDTDLHTG--DYCKPCNCSGNINPQD------PGSC 1891
C C+ G+ C++CA Y P E D TG + C+ C C+G+ + S
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAI--FSKN--CTACICDEFGMAD-------- 1939
+ G C C +NT G C C PGFY D FS C C C G A
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 1940 CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC 1995
CD + G C C+PGV G +CDRC +WG GC PC+C + CD G C
Sbjct: 413 CDPSNGDCPCKPGVAGRRCDRCMVGYWGFG-DYGCRPCDC-----AGSCDPITGDC 462
Score = 96.7 bits (230), Expect = 1e-18
Identities = 69/203 (33%), Positives = 96/203 (47%), Gaps = 42/203 (20%)
Query: 1716 GVDYYMGDELVVRRATSVEECQ-CPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC 1774
G + + + + + T+ CQ C Y E A+G P+ C C+CNGH+D C
Sbjct: 284 GTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWE-AADGKTGAPNE-CRTCKCNGHADTC 341
Query: 1775 --DVNT---------GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICAC-PM- 1819
DVN G+C +C NT G +C+ C G++ D P C C+C P+
Sbjct: 342 HFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVG 401
Query: 1820 --PYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDY-CKP 1876
P+N+ CD S NG C C+PG G RC+ C GY+G GDY C+P
Sbjct: 402 SAVLPANSVTF-CDPS-NG---DCPCKPGVAGRRCDRCMVGYWGF--------GDYGCRP 448
Query: 1877 CNCSGNINPQDPGSCDSINGDCL 1899
C+C+ GSCD I GDC+
Sbjct: 449 CDCA--------GSCDPITGDCI 463
Score = 82.6 bits (195), Expect = 2e-14
Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 33/182 (18%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP------------ACEECNCDPRGVTASF-----A 650
+G C CK N G+ C C + + P C C C+ T F
Sbjct: 290 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE 349
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP-LYWNLQE--YNPFGCEQCNCNLAGTL----NS 703
G+ G C+ +G+ C CKP Y +L+ P C+ C+C+ G+ NS
Sbjct: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
+ C+ +G C CK V R+CD+C+ G++ +GC CDC GS CD TG
Sbjct: 410 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDC--AGS----CDPITG 460
Query: 764 QC 765
C
Sbjct: 461 DC 462
Score = 81.8 bits (193), Expect = 4e-14
Identities = 52/171 (30%), Positives = 75/171 (43%), Gaps = 34/171 (19%)
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS---------KNCTACICD----- 1933
PG+ ++G C+ C +NTAG+ C CAP Y D + C C C+
Sbjct: 283 PGTFHMVHGKCM-CKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRTCKCNGHADT 340
Query: 1934 -EFGM----ADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCGI- 1981
F + A + + G C C+ G+ C RC P + + C PC+C
Sbjct: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
Query: 1982 ------ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNC 2026
A+ T CD NG C C GV G++CD+C G+W + GC C+C
Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/202 (29%), Positives = 85/202 (42%), Gaps = 47/202 (23%)
Query: 356 DVCQPCQ-CDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP------------N 402
D C P P + G G+C C+ C CA Y D P
Sbjct: 269 DQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNE 328
Query: 403 CKPCTCN---------LNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGYY-------- 444
C+ C CN +N E + G+C C++N G+ C+ C+ G+Y
Sbjct: 329 CRTCKCNGHADTCHFDVNVWEASG-NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
Query: 445 SPE-CKNCECNTVGSVSY------VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CK 495
+P+ CK C C+ VGS CD GDC CK +GR C++C GY+ + C+
Sbjct: 388 APDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCR 447
Query: 496 PCNCDTSGTEPSICDDVSGQCI 517
PC+C S CD ++G CI
Sbjct: 448 PCDCAGS------CDPITGDCI 463
Score = 77.0 bits (181), Expect = 1e-12
Identities = 60/209 (28%), Positives = 84/209 (40%), Gaps = 44/209 (21%)
Query: 540 GRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP---------- 588
G QC+P + P + T GKC C N G+ C C+P Y P
Sbjct: 266 GHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGA 325
Query: 589 --DCLSCNC---------DVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY------ 630
+C +C C DV+ S G+C C+ N +G C C+ FY
Sbjct: 326 PNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRP 385
Query: 631 -NYP-ACEECNCDPRGVTASFAGCGSV--PAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
+ P AC+ C+C P G A + P+ C CK V GR C+ C YW +Y
Sbjct: 386 FSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY- 444
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
GC C+C G+C+ +G C+
Sbjct: 445 --GCRPCDC--------AGSCDPITGDCI 463
Score = 77.0 bits (181), Expect = 1e-12
Identities = 58/177 (32%), Positives = 75/177 (42%), Gaps = 41/177 (23%)
Query: 1357 GQCPCKPNVIGRTCSAC-----------RTGYYGFPN-CRPCHC---PSTAICDDN---- 1397
G+C CK N G C C G G PN CR C C T D N
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 1398 ------GMC-ICPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLG---VVGNQL 1442
G+C C N EG+ C RCKP + F C C+C+P+G + N +
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 1443 Q-CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTYDVCDQNTAQC 1497
C+ +G C C+ V GR CD C+ G++ F D Y C C+ G+ CD T C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD-YGCRPCDCAGS----CDPITGDC 462
Score = 71.7 bits (168), Expect = 5e-11
Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 39/164 (23%)
Query: 423 GLCPCKYNYAGKSCEICEDGYY------------SP-ECKNCECNTVGSVSYVC------ 463
G C CK+N AG C+ C Y +P EC+ C+CN +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 464 --DKLTGDCT-CKSKYSGRTCNQCQAGYY-------NYP-TCKPCNCDTSGT------EP 506
++ G C C+ G+ C +C+ G+Y + P CKPC+C G+
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 507 SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
+ CD +G C CK G G RCD+C+ GY+ G + C PC+C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFG-DYGCRPCDC 451
Score = 68.1 bits (159), Expect = 6e-10
Identities = 60/208 (28%), Positives = 79/208 (37%), Gaps = 38/208 (18%)
Query: 1384 RPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFN-----FDVQRG----CDDCNCNP 1434
RP P T +G C+C N G +C C P + D + G C C CN
Sbjct: 278 RPVKAPGTFHMV-HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNG 336
Query: 1435 ------LGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHY-------AFPD-CYQCT 1479
V + G C C+ N G+ C C PG Y + PD C C+
Sbjct: 337 HADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCS 396
Query: 1480 CNRHGT------TYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
C+ G+ + CD + C CK V G+ CD C Y+ D GC C C G
Sbjct: 397 CHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDCAG 453
Query: 1534 K----TTRCSSSYYTWAAIDEMVDWYPV 1557
T C SS+ E+ D+ PV
Sbjct: 454 SCDPITGDCISSHTDIDWYHEVPDFRPV 481
Score = 63.7 bits (148), Expect = 1e-08
Identities = 34/73 (46%), Positives = 39/73 (53%), Gaps = 11/73 (15%)
Query: 1338 RPCLCDFMGSTELECN--TF----GGQCPCKPNVIGRTCSACRTGYYGFPN--CRPCHCP 1389
+PC C +GS L N TF G CPCKP V GR C C GY+GF + CRPC C
Sbjct: 393 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCA 452
Query: 1390 STAICDD-NGMCI 1401
+ CD G CI
Sbjct: 453 GS--CDPITGDCI 463
Score = 62.5 bits (145), Expect = 3e-08
Identities = 60/219 (27%), Positives = 88/219 (40%), Gaps = 28/219 (12%)
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
Y +D+ C CN + C P G P K A + + +C C+ N
Sbjct: 251 YAIYDFIVKGSCFCN---GHADQCIPVHGFRPVK---APGTFHMVHG-----KCM-CKHN 298
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPTCKPCNCDTSGTEPSICDDV 512
T GS C L D ++ G+T N+C+ N C+ D + E S +
Sbjct: 299 TAGSHCQHCAPLYNDRPWEAA-DGKTGAPNECRTCKCN-GHADTCHFDVNVWEAS-GNRS 355
Query: 513 SGQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGS------TSTSCS- 561
G C C+ G C +C G+Y + C PC+C P GS + T C
Sbjct: 356 GGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDP 415
Query: 562 ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS 600
++G C C G +CD+C GY+ + D CD +GS
Sbjct: 416 SNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGS 454
Score = 61.3 bits (142), Expect = 6e-08
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 32/160 (20%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDH----WGLNTGLG-----CTPCNCGIASESTQCDDD---- 1991
G C+C+ G C CAP + W G C C C +++ D +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 1992 -----NGQCR-CAKGVTGKQCDQCAAGFWNYTK------DGCDHCNCNT-------GYSV 2032
G C C G+ C +C GF+ + D C C+C+ SV
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 2033 GFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECD 2072
F + G C C PGV G +CDRC + GC CD
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCD 450
Score = 60.1 bits (139), Expect = 1e-07
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 34/163 (20%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQ-------VLGRERQCVPCNCDPTGST-------- 556
V G+C+CK G C C Y + G +C C C+ T
Sbjct: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 348
Query: 557 -STSCSADGKC-NCLTNFGGAQCDQCSPGYYK-------YPD-CLSCNCDVSGSI----- 601
++ + G C +C N G C +C PG+Y+ PD C C+C GS
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
Query: 602 -GSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
+ CD NG C CK G +CD C ++ + C C+C
Sbjct: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 59.3 bits (137), Expect = 3e-07
Identities = 49/141 (34%), Positives = 56/141 (39%), Gaps = 23/141 (16%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEYN---PFGCEQCNCN-LAGT----LNSLGACN 708
C CK G C C PLY W + P C C CN A T +N A
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
Query: 709 TKSGQ-CVCKQHVGERQ-CDQCLDGFYRLQTNDVFG---CTECDCDIGGS--IDNN---- 757
+SG C QH E Q C +C GFYR C C C GS + N
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 758 CDKTTGQCHCHSRVEGRRCDQ 778
CD + G C C V GRRCD+
Sbjct: 413 CDPSNGDCPCKPGVAGRRCDR 433
Score = 38.3 bits (85), Expect = 0.52
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN 1783
+C C G C++C G++ C PC C G CD TG C++
Sbjct: 419 DCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG---SCDPITGDCIS 464
>L34155-1|AAA59483.1| 1713|Homo sapiens epiligrin alpha 3 subunit
protein.
Length = 1713
Score = 198 bits (484), Expect = 2e-49
Identities = 256/1257 (20%), Positives = 499/1257 (39%), Gaps = 108/1257 (8%)
Query: 1913 CAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWGLN 1969
C+PG+Y D +++ C C C+ C +G CV C+ GE C+RC ++G
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 106
Query: 1970 TGLGCTPCNCGIASE-STQCDDDNG--QCRCAKGVTGKQCDQCAAGFW-NYTKDG--CDH 2023
C C C + +T C + G +C C G TG QC++CA G++ N K G C
Sbjct: 107 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 166
Query: 2024 CNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVE 2083
C+CN+ +G TG C + E D P E C +CDSC L+ +
Sbjct: 167 CSCNSNGQLGSCHPLTGDC-----INQEPKDSSPA-------EECDDCDSCVMTLLNDLA 214
Query: 2084 DLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLET 2143
+ L + + S +++ ++ Q + LR ++ ++ I S I+ LE
Sbjct: 215 TMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-ISNHGSKIEGLER 273
Query: 2144 SAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADL-----A 2198
+L + E + +A L + R + +E + V+++V L
Sbjct: 274 ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISG 333
Query: 2199 TGLELSQQPKVDSAL--TEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPV 2256
T E + P D + EA+++ ++ +++ ++AEA + + R+ + +
Sbjct: 334 TDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTH 393
Query: 2257 NEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGN 2316
+ ++ S+ ++ E + KL D+ A A A LN +N + G
Sbjct: 394 QGENNGLAN-------SIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERA-LGA 445
Query: 2317 KVNSVTKLNTAAMGDLIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2376
V ++N+ D ++
Sbjct: 446 IQRQVKEINSL-QSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSD 504
Query: 2377 XTGELPQFEHLTS---EATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQ 2433
EL + TS EA HA L+ A L E+ + + +
Sbjct: 505 KVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILN 564
Query: 2434 EINXXXXXXXXXXXXXXNV--TKLNRILDERVRPARERSSSLLADATKAQHAVDQKLLPN 2491
I + T + L + + S LL +A Q + Q++ P
Sbjct: 565 AIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPA 624
Query: 2492 LTATEEVLRKIRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRVNATIGTTFSVMS 2550
L ++ L + D + ++ + A V T V+
Sbjct: 625 LNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLD 684
Query: 2551 HLGPELATSKDWAQTLPKLADEG-QKMTSNVESHLKNINDMEPQISSSYHTVKMXXXXXX 2609
L P + T + +E +K ++ ++ + + + P + ++
Sbjct: 685 GLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLG 744
Query: 2610 XXXXXXXXKLQKLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYF 2669
+ ++++L++QAR A+++ V + F+ S ++ RLP+ ++++ T +S +
Sbjct: 745 NISD----NMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFL 800
Query: 2670 R---TKEKDG----FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQD 2722
+ ++E G F++YLGN + S DY+ + + +G V ++GD
Sbjct: 801 QRPNSRENGGTENMFVMYLGN-------KDASRDYIGMAVVDGQLTCVYNLGDRE----- 848
Query: 2723 PARVSIDKMVADNRWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA---DLPGH--HT 2776
A + +D+++ + + ++DR+ +R+ R + G + + D+ G +T
Sbjct: 849 -AELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNT 907
Query: 2777 IFNLDKEKSKLYVGGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGAR 2835
+ NLD E YVGG P D KL +SFP ++G IE + + + L+NF L
Sbjct: 908 LLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTE 967
Query: 2836 QRDKLISSQSGPQEYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAPNGLIYLVGEGGY 2894
+ + Y F+G GYA + + + P Q + +T GL++ G
Sbjct: 968 VEPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVDRGLLFFAENGDR 1023
Query: 2895 FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKA 2954
F SL ++DG++ ++ L N+E G A N+G+ H + + + + ++ +V
Sbjct: 1024 FISLNIEDGKLMVRYKL-NSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDV--- 1079
Query: 2955 ESNSPSADIPSLDTMNFGGNNKGI---LQVPDRGFDGCMRQISINGVNLDLSENLESIGM 3011
++ ++ T GG I + F GCM+ + + L+ +++G+
Sbjct: 1080 QNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLN---DTVGV 1136
Query: 3012 AYGC----QFASLVSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPNGLLFVYVSRTQT 3064
C + SF+ L F D+ +++ Q + F+T +P+G+L + + T+
Sbjct: 1137 TKKCSEDWKLVRSASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTR- 1194
Query: 3065 AIMPDSISLSLVNG--KLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD 3119
++ ++L +G +L + TY D H ++V + S L+L++DD
Sbjct: 1195 -----NLQVTLEDGYIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDD 1246
Score = 148 bits (359), Expect = 3e-34
Identities = 70/154 (45%), Positives = 95/154 (61%), Gaps = 19/154 (12%)
Query: 1750 CAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
C+ G+YR L +G CVPC CNGHS+QC +GIC+NC NT G+HCE C GY+G+A
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 107
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G+ R ACP P+ +N+FA C + NG + C+C+ GY G +CE CA GY+G P+
Sbjct: 108 HGSCR-----ACPCPH-TNSFATGCVV--NGGDVRCSCKAGYTGTQCERCAPGYFGNPQ- 158
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
G C+PC+C+ N GSC + GDC+
Sbjct: 159 ---KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 186
Score = 104 bits (249), Expect = 7e-21
Identities = 89/363 (24%), Positives = 160/363 (44%), Gaps = 24/363 (6%)
Query: 3309 RFGSRNVSRIEYAKLPGRQLEG-FDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
+FG S + + KLP L+ + +T +G ++F+ + KN F+A ++
Sbjct: 1368 QFGDIPTSHLLF-KLPQELLKPRSQFAVDMQTTSSRG-LVFHTGT---KN--SFMALYLS 1420
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPL 3427
+L + G+ I S ND WHTV +G G+L VD E S+ N+ +
Sbjct: 1421 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 1480
Query: 3428 SLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN-I 3486
S+ P Y G + + + N F+GCLK ++ + + ++ C+ +
Sbjct: 1481 SIRAPVYLGS--PPSGKPKSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 1535
Query: 3487 EDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK-DYMVLELL 3545
E G+YF + ++ L + +G E + +RPR+ TG+L+ + + ++ + L
Sbjct: 1536 EKGIYF----SEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1591
Query: 3546 DSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFS-KPGIGA 3604
+V A++++G G + ++ K LCDG WH + D S G
Sbjct: 1592 AGKVTASMDSGAG--GTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIP 1649
Query: 3605 YTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRG-AHVG 3663
+ T L++GG + +R + + F GC+RNI V PV V + +G +
Sbjct: 1650 FPPASTQEPLHLGGAPANLTTLR-IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 1708
Query: 3664 VCP 3666
CP
Sbjct: 1709 GCP 1711
Score = 98.7 bits (235), Expect = 3e-19
Identities = 55/164 (33%), Positives = 76/164 (46%), Gaps = 18/164 (10%)
Query: 1855 CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCA 1914
C+ GYY + L+TG C PCNC+G+ N C +G C+ C +NTAG C C
Sbjct: 48 CSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQ 99
Query: 1915 PGFYGDAIFSKNCTACICDEFG--MADCDSTTG--TCVCRPGVIGEKCDRCAPDHWG--L 1968
G+YG+A+ +C AC C C G C C+ G G +C+RCAP ++G
Sbjct: 100 EGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQ 158
Query: 1969 NTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
G C PC+C + C G C ++CD C
Sbjct: 159 KFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 202
Score = 94.7 bits (225), Expect = 6e-18
Identities = 56/168 (33%), Positives = 83/168 (49%), Gaps = 27/168 (16%)
Query: 384 EFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSC 436
EF+P C+ GY+ D+ C PC CN + + C G+C C++N AG+ C
Sbjct: 41 EFRPSQ--GCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHC 95
Query: 437 EICEDGYYSP----ECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQAGYYN 490
E C++GYY C+ C C S + C GD C+CK+ Y+G C +C GY+
Sbjct: 96 ERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG 155
Query: 491 YP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 156 NPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 202
Score = 93.9 bits (223), Expect = 1e-17
Identities = 53/165 (32%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 479 RTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCL 531
R C GYY Y C PCNC+ + C D SG C+ C+ G C++C
Sbjct: 43 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHCERCQ 99
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQCSPGYYKYP 588
GYY + C C C T S +T C +G +C+C + G QC++C+PGY+ P
Sbjct: 100 EGYYGNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 157
Query: 589 -----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C C+C+ +G +GS G C K + +CD C
Sbjct: 158 QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 202
Score = 89.8 bits (213), Expect = 2e-16
Identities = 57/164 (34%), Positives = 74/164 (45%), Gaps = 36/164 (21%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PCNC+ H+ +C +G G C+NCQHNT G +C +C+ Y
Sbjct: 64 CVPCNCNGHSNQCQ------------------DGSGICVNCQHNTAGEHCERCQEGY--- 102
Query: 348 YGKRWDELDVCQPCQCDPH---FSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
YG C+ C C PH F+TG C G RC C+ + C CA GYF P
Sbjct: 103 YGNAVH--GSCRACPC-PHTNSFATG-CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQ 158
Query: 402 ----NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
+C+PC+CN NG G C P G C + E C+D
Sbjct: 159 KFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDD 201
Score = 85.8 bits (203), Expect = 3e-15
Identities = 52/160 (32%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 580 CSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFYNY 632
CSPGYY+ Y C+ CNC+ G D +G+C +C+ N G C+ C+E +Y
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 105
Query: 633 PACEECNCDPRGVTASFA-GCGSVPAGEL-CQCKDRVQGRICNDCKPLYWNLQEYNPFGC 690
C P T SFA GC V G++ C CK G C C P Y+ + C
Sbjct: 106 AVHGSCRACPCPHTNSFATGC-VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSC 164
Query: 691 EQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
+ C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 165 QPCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 201
Score = 74.9 bits (176), Expect = 5e-12
Identities = 47/171 (27%), Positives = 66/171 (38%), Gaps = 18/171 (10%)
Query: 1368 RTCSACRTGYY----GF--PNCRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYT 1418
R C GYY G C PC+C S D +G+C+ C N GE+C+RC+
Sbjct: 43 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGY 102
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP----- 1473
+ V C C C +C+C+ G C+ C PG++ P
Sbjct: 103 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 162
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCY---CKTNVRGQACDTCKEEYFNLQDD 1521
C C+CN +G C T C K + + CD C L +D
Sbjct: 163 SCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLND 212
Score = 65.7 bits (153), Expect = 3e-09
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 67 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 113
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + +NG G +C +C+ G C +C P Y +G
Sbjct: 114 CPC----------PHTNSFATGCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 156
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 157 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 205
Score = 61.3 bits (142), Expect = 6e-08
Identities = 34/111 (30%), Positives = 42/111 (37%), Gaps = 11/111 (9%)
Query: 1427 CDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYA---FPDCYQCTCNR 1482
C CNCN G+ QC+ SG C C+ N G C+ C G+Y C C C
Sbjct: 64 CVPCNCN-----GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPH 118
Query: 1483 HGTTYDVCDQN--TAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ C N +C CK G C+ C YF C C C
Sbjct: 119 TNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 169
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQC--NGHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P G C PC C NG C TG C+N D++
Sbjct: 135 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 194
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 195 PAEECDDCDS 204
Score = 50.8 bits (116), Expect = 9e-05
Identities = 60/292 (20%), Positives = 118/292 (40%), Gaps = 30/292 (10%)
Query: 2725 RVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEK 2784
R+ + D +W+ V+ G + +L + D + ++E LPG+ TI +
Sbjct: 1436 RIKSKEKCNDGKWHTVVFGHDGEKGRLVV--------DGLRAREGSLPGNSTI----SIR 1483
Query: 2785 SKLYVGGVPSDAKLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQ 2844
+ +Y+G PS K + + +F G ++ + P+ + ++ + S
Sbjct: 1484 APVYLGSPPS-GKPKSLPTNSFVGCLKNFQLDSKPL----YTPSSSFG-------VSSCL 1531
Query: 2845 SGPQE---YRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
GP E Y + G+ +A L P+ V LI++ + G + ++
Sbjct: 1532 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1591
Query: 2902 DGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSA 2961
G+V + G V ++ DG+WH + L +D + P
Sbjct: 1592 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 1651
Query: 2962 DIPSLDTMNFGG--NNKGILQVPD-RGFDGCMRQISINGVNLDLSENLESIG 3010
+ + ++ GG N L++P + F GC+R I +N + + ++E LE G
Sbjct: 1652 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 1703
Score = 50.0 bits (114), Expect = 2e-04
Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 9/309 (2%)
Query: 2866 LTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
L P+S Q + +T + GL++ G F +L + GR L +LG + + +
Sbjct: 1386 LKPRS-QFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGR--LVFALGTDGKKLRIKSKEK 1442
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKG-ILQVPDR 2984
NDGKWH + K L VD + S ++ I + G G +P
Sbjct: 1443 CNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTN 1502
Query: 2985 GFDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTL 3044
F GC++ ++ L + + G + F+ ++ P+ L
Sbjct: 1503 SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKL 1562
Query: 3045 KFKTAKPNGL--LFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-TGLNTYNDSQW 3101
F + +P L + +++ + + V + + T + D QW
Sbjct: 1563 VF-SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQW 1621
Query: 3102 HVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFT 3161
H + VT L L +D ++ P P L +GG P + + + F
Sbjct: 1622 HSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGA-PANLTTLRIPVWKSFF 1680
Query: 3162 GCIGDATIN 3170
GC+ + +N
Sbjct: 1681 GCLRNIHVN 1689
Score = 48.4 bits (110), Expect = 5e-04
Identities = 31/131 (23%), Positives = 48/131 (36%), Gaps = 9/131 (6%)
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C CNC+ ++ GS G C+ G C C+ Y+ + C C
Sbjct: 64 CVPCNCNGH---SNQCQDGS---GICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACP 115
Query: 695 CNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSI 754
C + + N +C CK QC++C G++ C C C+ G +
Sbjct: 116 CPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL 175
Query: 755 DNNCDKTTGQC 765
+C TG C
Sbjct: 176 -GSCHPLTGDC 185
Score = 48.4 bits (110), Expect = 5e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 16/122 (13%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGG--QCPCKPN 1364
C + + + C+E + + + R C C S C GG +C CK
Sbjct: 83 CVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 140
Query: 1365 VIGRTCSACRTGYYGFP-----NCRPCHCPST---AICDD-NGMCIC--PKNVE-GENCD 1412
G C C GY+G P +C+PC C S C G CI PK+ E CD
Sbjct: 141 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECD 200
Query: 1413 RC 1414
C
Sbjct: 201 DC 202
Score = 45.6 bits (103), Expect = 0.003
Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 6/85 (7%)
Query: 1738 CPRAYRGLSCEQCAEGHY-RLPSGFCVPCQC---NGHSDQCDVNTG-ICLNCADNTIGDH 1792
C G CE+C EG+Y G C C C N + C VN G + +C G
Sbjct: 86 CQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQ 145
Query: 1793 CEFCMSGYHGDATVGTPRDCLICAC 1817
CE C GY G+ C C+C
Sbjct: 146 CERCAPGYFGNPQ-KFGGSCQPCSC 169
>AY330211-1|AAP92113.1| 605|Homo sapiens netrin 4 protein.
Length = 605
Score = 198 bits (484), Expect = 2e-49
Identities = 124/400 (31%), Positives = 186/400 (46%), Gaps = 50/400 (12%)
Query: 34 CDICDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVF 89
CD C+A H P D RTWWQS + + +DL EF+ ++
Sbjct: 77 CDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLI 131
Query: 90 VKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVICSTE 149
V M SPRP VL++S D+GKT+KP++YF+ + C FG E + K + IC+++
Sbjct: 132 V-MFKSPRPAAMVLDRSQDFGKTWKPYKYFATN---CSATFGLED--DVVKKGA-ICTSK 184
Query: 150 YSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVAR 209
YS P GE+ L+ + +++ V QE + N+R++LL+ ++ R
Sbjct: 185 YSSPFPCTGGEVIFKALSPPYDTENPYSAKV-QEQLKIINLRVQLLKRQSC-----PCQR 238
Query: 210 QDPTVTRRYF--YSIKDISIGGRCMCNGHADTC------EPADPAGNLNIL--VCRCQHN 259
D ++F Y+I D + G C CNGHAD C P G +++ C C+HN
Sbjct: 239 NDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHN 298
Query: 260 TCGPQCNKCCSGFEQKKWRISQNWDRF--SCEPCNCHNHTTECTYDPEIDEKRLSLDING 317
T G C C + + W + C C C+ H C +D + E +G
Sbjct: 299 TAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA------SG 352
Query: 318 RYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST---GN--- 371
GG C +CQHNTEG C +C+P +YR + + D C+PC C P S N
Sbjct: 353 N-RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVT 411
Query: 372 -CEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
C+ +G C C+P C C GY+ + + C+PC C
Sbjct: 412 FCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 92.3 bits (219), Expect = 3e-17
Identities = 68/201 (33%), Positives = 94/201 (46%), Gaps = 42/201 (20%)
Query: 1716 GVDYYMGDELVVRRATSVEECQ-CPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC 1774
G + + + + + T+ CQ C Y E A+G P+ C C+CNGH+D C
Sbjct: 284 GTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWE-AADGKTGAPNE-CRACKCNGHADTC 341
Query: 1775 --DVNT---------GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICAC-PMP 1820
DVN G+C +C NT G +C+ C G++ D P C C+C P+
Sbjct: 342 HFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVG 401
Query: 1821 ---YPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDY-CKP 1876
P+N+ CD S NG C C+PG G RC+ C GY+G GDY C+P
Sbjct: 402 SAVLPANSVTF-CDPS-NGD---CPCKPGVAGRRCDRCMVGYWGF--------GDYGCRP 448
Query: 1877 CNCSGNINPQDPGSCDSINGD 1897
C+C+ GSCD I GD
Sbjct: 449 CDCA--------GSCDPITGD 461
Score = 83.4 bits (197), Expect = 1e-14
Identities = 53/171 (30%), Positives = 76/171 (44%), Gaps = 34/171 (19%)
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS---------KNCTACICD----- 1933
PG+ ++G C+ C +NTAG+ C CAP Y D + C AC C+
Sbjct: 283 PGTFHMVHGKCM-CKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRACKCNGHADT 340
Query: 1934 -EFGM----ADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCGI- 1981
F + A + + G C C+ G+ C RC P + + C PC+C
Sbjct: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
Query: 1982 ------ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNC 2026
A+ T CD NG C C GV G++CD+C G+W + GC C+C
Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 79.0 bits (186), Expect = 3e-13
Identities = 53/180 (29%), Positives = 77/180 (42%), Gaps = 33/180 (18%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP------------ACEECNCDPRGVTASF-----A 650
+G C CK N G+ C C + + P C C C+ T F
Sbjct: 290 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWE 349
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP-LYWNLQE--YNPFGCEQCNCNLAGTL----NS 703
G+ G C+ +G+ C CKP Y +L+ P C+ C+C+ G+ NS
Sbjct: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
+ C+ +G C CK V R+CD+C+ G++ +GC CDC GS CD TG
Sbjct: 410 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDC--AGS----CDPITG 460
Score = 76.6 bits (180), Expect = 2e-12
Identities = 53/161 (32%), Positives = 68/161 (42%), Gaps = 37/161 (22%)
Query: 1357 GQCPCKPNVIGRTCSAC-----------RTGYYGFPN-CRPCHC---PSTAICDDN---- 1397
G+C CK N G C C G G PN CR C C T D N
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA 350
Query: 1398 ------GMC-ICPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLG---VVGNQL 1442
G+C C N EG+ C RCKP + F C C+C+P+G + N +
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 1443 Q-CEADSGKCACRENVRGRVCDHCVPGHYAFPD--CYQCTC 1480
C+ +G C C+ V GR CD C+ G++ F D C C C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 75.8 bits (178), Expect = 3e-12
Identities = 59/202 (29%), Positives = 84/202 (41%), Gaps = 47/202 (23%)
Query: 356 DVCQPCQ-CDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP------------N 402
D C P P + G G+C C+ C CA Y D P
Sbjct: 269 DQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNE 328
Query: 403 CKPCTCN---------LNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGYY-------- 444
C+ C CN +N E + G+C C++N G+ C+ C+ G+Y
Sbjct: 329 CRACKCNGHADTCHFDVNVWEASG-NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
Query: 445 SPE-CKNCECNTVGSVSY------VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CK 495
+P+ CK C C+ VGS CD GDC CK +GR C++C GY+ + C+
Sbjct: 388 APDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCR 447
Query: 496 PCNCDTSGTEPSICDDVSGQCI 517
PC+C S CD ++G I
Sbjct: 448 PCDCAGS------CDPITGDRI 463
Score = 74.5 bits (175), Expect = 6e-12
Identities = 56/189 (29%), Positives = 76/189 (40%), Gaps = 36/189 (19%)
Query: 540 GRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP---------- 588
G QC+P + P + T GKC C N G+ C C+P Y P
Sbjct: 266 GHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGA 325
Query: 589 --DCLSCNC---------DVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY------ 630
+C +C C DV+ S G+C C+ N +G C C+ FY
Sbjct: 326 PNECRACKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRP 385
Query: 631 -NYP-ACEECNCDPRGVTASFAGCGSV--PAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
+ P AC+ C+C P G A + P+ C CK V GR C+ C YW +Y
Sbjct: 386 FSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY- 444
Query: 687 PFGCEQCNC 695
GC C+C
Sbjct: 445 --GCRPCDC 451
Score = 70.9 bits (166), Expect = 8e-11
Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 39/164 (23%)
Query: 423 GLCPCKYNYAGKSCEICEDGYY------------SP-ECKNCECNTVGSVSYVC------ 463
G C CK+N AG C+ C Y +P EC+ C+CN +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA 350
Query: 464 --DKLTGDCT-CKSKYSGRTCNQCQAGYY-------NYP-TCKPCNCDTSGT------EP 506
++ G C C+ G+ C +C+ G+Y + P CKPC+C G+
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 507 SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
+ CD +G C CK G G RCD+C+ GY+ G + C PC+C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFG-DYGCRPCDC 451
Score = 64.5 bits (150), Expect = 7e-09
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 28/231 (12%)
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
Y +D+ C CN + C P G P K A + + +C C+ N
Sbjct: 251 YAIYDFIVKGSCFCN---GHADQCIPVHGFRPVK---APGTFHMVHG-----KCM-CKHN 298
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPTCKPCNCDTSGTEPSICDDV 512
T GS C L D ++ G+T N+C+A N C+ D + E S +
Sbjct: 299 TAGSHCQHCAPLYNDRPWEAA-DGKTGAPNECRACKCN-GHADTCHFDVNVWEAS-GNRS 355
Query: 513 SGQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGS------TSTSCS- 561
G C C+ G C +C G+Y + C PC+C P GS + T C
Sbjct: 356 GGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDP 415
Query: 562 ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCH 612
++G C C G +CD+C GY+ + D CD +GS D H
Sbjct: 416 SNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDRISSH 466
Score = 64.5 bits (150), Expect = 7e-09
Identities = 52/180 (28%), Positives = 68/180 (37%), Gaps = 34/180 (18%)
Query: 1384 RPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFN-----FDVQRG----CDDCNCNP 1434
RP P T +G C+C N G +C C P + D + G C C CN
Sbjct: 278 RPVKAPGTFHMV-HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNG 336
Query: 1435 ------LGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHY-------AFPD-CYQCT 1479
V + G C C+ N G+ C C PG Y + PD C C+
Sbjct: 337 HADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCS 396
Query: 1480 CNRHGT------TYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
C+ G+ + CD + C CK V G+ CD C Y+ D GC C C G
Sbjct: 397 CHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDCAG 453
Score = 62.1 bits (144), Expect = 4e-08
Identities = 31/66 (46%), Positives = 36/66 (54%), Gaps = 10/66 (15%)
Query: 1338 RPCLCDFMGSTELECN--TF----GGQCPCKPNVIGRTCSACRTGYYGFPN--CRPCHCP 1389
+PC C +GS L N TF G CPCKP V GR C C GY+GF + CRPC C
Sbjct: 393 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCA 452
Query: 1390 STAICD 1395
+ CD
Sbjct: 453 GS--CD 456
Score = 61.3 bits (142), Expect = 6e-08
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 32/160 (20%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDH----WGLNTGLG-----CTPCNCGIASESTQCDDD---- 1991
G C+C+ G C CAP + W G C C C +++ D +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEA 350
Query: 1992 -----NGQCR-CAKGVTGKQCDQCAAGFWNYTK------DGCDHCNCNT-------GYSV 2032
G C C G+ C +C GF+ + D C C+C+ SV
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 2033 GFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECD 2072
F + G C C PGV G +CDRC + GC CD
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCD 450
Score = 60.1 bits (139), Expect = 1e-07
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 34/163 (20%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQ-------VLGRERQCVPCNCDPTGST-------- 556
V G+C+CK G C C Y + G +C C C+ T
Sbjct: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVW 348
Query: 557 -STSCSADGKC-NCLTNFGGAQCDQCSPGYYK-------YPD-CLSCNCDVSGSI----- 601
++ + G C +C N G C +C PG+Y+ PD C C+C GS
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
Query: 602 -GSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
+ CD NG C CK G +CD C ++ + C C+C
Sbjct: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 59.3 bits (137), Expect = 3e-07
Identities = 49/141 (34%), Positives = 56/141 (39%), Gaps = 23/141 (16%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEYN---PFGCEQCNCN-LAGT----LNSLGACN 708
C CK G C C PLY W + P C C CN A T +N A
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRACKCNGHADTCHFDVNVWEASG 352
Query: 709 TKSGQ-CVCKQHVGERQ-CDQCLDGFYRLQTNDVFG---CTECDCDIGGS--IDNN---- 757
+SG C QH E Q C +C GFYR C C C GS + N
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 758 CDKTTGQCHCHSRVEGRRCDQ 778
CD + G C C V GRRCD+
Sbjct: 413 CDPSNGDCPCKPGVAGRRCDR 433
>X85107-1|CAA59428.1| 1238|Homo sapiens alpha3a subunit of laminin 5
protein.
Length = 1238
Score = 186 bits (454), Expect = 1e-45
Identities = 242/1199 (20%), Positives = 470/1199 (39%), Gaps = 100/1199 (8%)
Query: 1913 CAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWGLN 1969
C+PG+Y D +++ C C C+ C +G CV C+ GE C+RC ++G
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 106
Query: 1970 TGLGCTPCNCGIASESTQCDDDNG---QCRCAKGVTGKQCDQCAAGFW-NYTKDG--CDH 2023
C C C + C NG +C C G TG QC++CA G++ N K G C
Sbjct: 107 VHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 166
Query: 2024 CNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVE 2083
C+CN+ +G TG C + E D P E C +CDSC L+ +
Sbjct: 167 CSCNSNGQLGSCHPLTGDC-----INQEPKDSSPA-------EECDDCDSCVMTLLNDLA 214
Query: 2084 DLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLET 2143
+ L + + S +++ ++ Q + LR ++ ++ I S I+ LE
Sbjct: 215 TMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-ISNHGSKIEGLER 273
Query: 2144 SAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADL-----A 2198
+L + E + +A L + R + +E + V+++V L
Sbjct: 274 ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISG 333
Query: 2199 TGLELSQQPKVDSAL--TEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPV 2256
T E + P D + EA+++ ++ +++ ++AEA + + R+ + +
Sbjct: 334 TDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTH 393
Query: 2257 NEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLAQHTAHTAEELNTKNRLSKFGN 2316
+ ++ S+ ++ E + KL D+ A A A LN +N + G
Sbjct: 394 QGENNGLAN-------SIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERA-LGA 445
Query: 2317 KVNSVTKLNTAAMGDLIDAAYDIGNATYNNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2376
V ++N+ D ++
Sbjct: 446 IQRQVKEINSL-QSDFTKYLTTADSSLLQTNIALQLKEKSQKEYEKLAASLNEARQELSD 504
Query: 2377 XTGELPQFEHLTS---EATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQ 2433
EL + TS EA HA L+ A L E+ + + +
Sbjct: 505 KVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILN 564
Query: 2434 EINXXXXXXXXXXXXXXNV--TKLNRILDERVRPARERSSSLLADATKAQHAVDQKLLPN 2491
I + T + L + + S LL +A Q + Q++ P
Sbjct: 565 AIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPA 624
Query: 2492 LTATEEVLRKIRDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRVNATIGTTFSVMS 2550
L ++ L + D + ++ + A V T V+
Sbjct: 625 LNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLD 684
Query: 2551 HLGPELATSKDWAQTLPKLADEG-QKMTSNVESHLKNINDMEPQISSSYHTVKMXXXXXX 2609
L P + T + +E +K ++ ++ + + + P + ++
Sbjct: 685 GLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLG 744
Query: 2610 XXXXXXXXKLQKLKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYF 2669
+ ++ +L++QAR A+++ V + F+ S ++ RLP+ ++++ T +S +
Sbjct: 745 NISD----NMDRILELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFL 800
Query: 2670 R---TKEKDG----FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQD 2722
+ ++E G F++YLGN + S DY+ + + +G V ++GD
Sbjct: 801 QRPNSRENGGTENMFVMYLGN-------KDASRDYIGMAVVDGQLTCVYNLGDRE----- 848
Query: 2723 PARVSIDKMVADNRWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA---DLPGH--HT 2776
A + +D+++ + + ++DR+ +R+ R + G + + D+ G +T
Sbjct: 849 -AELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNT 907
Query: 2777 IFNLDKEKSKLYVGGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGAR 2835
+ NLD E YVGG P D KL +SFP ++G IE + + + L+NF L
Sbjct: 908 LLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTE 967
Query: 2836 QRDKLISSQSGPQEYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAPNGLIYLVGEGGY 2894
+ + + Y F+G GYA + + + P Q + +T GL++ G
Sbjct: 968 VQPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVDRGLLFFAENGDR 1023
Query: 2895 FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKA 2954
F SL ++DG++ ++ L N+E G A N+G+ H + + + + ++ +V
Sbjct: 1024 FISLNIEDGKLMVRYKL-NSELPKERGVGAAINNGRDHSIQIKIGKLQKRMWINVDV--- 1079
Query: 2955 ESNSPSADIPSLDTMNFGGNNKGI---LQVPDRGFDGCMRQISINGVNLDLSENLESIGM 3011
++ ++ T GG I + F GCM+ + + L+ +++G+
Sbjct: 1080 QNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLN---DTVGV 1136
Query: 3012 AYGC----QFASLVSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPNGLLFVYVSRTQ 3063
C + SF+ L F D+ +++ Q + F+T +P+ +L + + T+
Sbjct: 1137 TKKCSEDWKLVRSASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPSAILLDHQTWTR 1194
Score = 147 bits (357), Expect = 6e-34
Identities = 69/154 (44%), Positives = 95/154 (61%), Gaps = 19/154 (12%)
Query: 1750 CAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
C+ G+YR L +G CVPC CNGHS+QC +GIC+NC NT G+HCE C GY+G+A
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 107
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G+ R ACP P+ +N+F + C + NG + C+C+ GY G +CE CA GY+G P+
Sbjct: 108 HGSCR-----ACPCPH-TNSFGMCCVV--NGGDVRCSCKAGYTGTQCERCAPGYFGNPQ- 158
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
G C+PC+C+ N GSC + GDC+
Sbjct: 159 ---KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 186
Score = 102 bits (245), Expect = 2e-20
Identities = 58/165 (35%), Positives = 80/165 (48%), Gaps = 20/165 (12%)
Query: 1855 CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCA 1914
C+ GYY + L+TG C PCNC+G+ N C +G C+ C +NTAG C C
Sbjct: 48 CSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQ 99
Query: 1915 PGFYGDAIFSKNCTACIC---DEFGMADCDSTTG--TCVCRPGVIGEKCDRCAPDHWG-- 1967
G+YG+A+ +C AC C + FGM C G C C+ G G +C+RCAP ++G
Sbjct: 100 EGYYGNAVHG-SCRACPCPHTNSFGMC-CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 157
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
G C PC+C + C G C ++CD C
Sbjct: 158 QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 202
Score = 95.5 bits (227), Expect = 3e-18
Identities = 56/168 (33%), Positives = 82/168 (48%), Gaps = 27/168 (16%)
Query: 384 EFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSC 436
EF+P C+ GY+ D+ C PC CN + + C G+C C++N AG+ C
Sbjct: 41 EFRPSQ--GCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHC 95
Query: 437 EICEDGYYSP----ECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQAGYYN 490
E C++GYY C+ C C S C GD C+CK+ Y+G C +C GY+
Sbjct: 96 ERCQEGYYGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFG 155
Query: 491 YP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 156 NPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 202
Score = 90.6 bits (215), Expect = 9e-17
Identities = 52/165 (31%), Positives = 73/165 (44%), Gaps = 23/165 (13%)
Query: 479 RTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCL 531
R C GYY Y C PCNC+ + C D SG C+ C+ G C++C
Sbjct: 43 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHCERCQ 99
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQCSPGYYKYP 588
GYY + C C C T S C +G +C+C + G QC++C+PGY+ P
Sbjct: 100 EGYYGNAV--HGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 157
Query: 589 -----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C C+C+ +G +GS G C K + +CD C
Sbjct: 158 QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 202
Score = 88.6 bits (210), Expect = 4e-16
Identities = 54/162 (33%), Positives = 71/162 (43%), Gaps = 32/162 (19%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PCNC+ H+ +C +G G C+NCQHNT G +C +C+ Y
Sbjct: 64 CVPCNCNGHSNQCQ------------------DGSGICVNCQHNTAGEHCERCQEGY--- 102
Query: 348 YGKRWDELDVCQPCQCDPHFSTGNCEEESG---RCECRPEFQPPDCSSCAYGYFDYP--- 401
YG C+ C C S G C +G RC C+ + C CA GYF P
Sbjct: 103 YGNAVH--GSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 160
Query: 402 --NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
+C+PC+CN NG G C P G C + E C+D
Sbjct: 161 GGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDD 201
Score = 88.2 bits (209), Expect = 5e-16
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 580 CSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFYNY 632
CSPGYY+ Y C+ CNC+ G D +G+C +C+ N G C+ C+E +Y
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 105
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGEL-CQCKDRVQGRICNDCKPLYWNLQEYNPFGCE 691
C P T SF C V G++ C CK G C C P Y+ + C+
Sbjct: 106 AVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 165
Query: 692 QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 166 PCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 201
Score = 76.2 bits (179), Expect = 2e-12
Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 18/171 (10%)
Query: 1368 RTCSACRTGYY----GF--PNCRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYT 1418
R C GYY G C PC+C S D +G+C+ C N GE+C+RC+
Sbjct: 43 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGY 102
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP----- 1473
+ V C C C G +C+C+ G C+ C PG++ P
Sbjct: 103 YGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 162
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCY---CKTNVRGQACDTCKEEYFNLQDD 1521
C C+CN +G C T C K + + CD C L +D
Sbjct: 163 SCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLND 212
Score = 66.1 bits (154), Expect = 2e-09
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 67 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 113
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + + +NG G +C +C+ G C +C P Y +G
Sbjct: 114 CPC----------PHTNSFGMCCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 156
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 157 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 205
Score = 62.9 bits (146), Expect = 2e-08
Identities = 34/112 (30%), Positives = 45/112 (40%), Gaps = 13/112 (11%)
Query: 1427 CDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYA---FPDCYQCTCNR 1482
C CNCN G+ QC+ SG C C+ N G C+ C G+Y C C C
Sbjct: 64 CVPCNCN-----GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP- 117
Query: 1483 HGTTYDVC---DQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
H ++ +C + +C CK G C+ C YF C C C
Sbjct: 118 HTNSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 169
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQC--NGHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P G C PC C NG C TG C+N D++
Sbjct: 135 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 194
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 195 PAEECDDCDS 204
Score = 50.4 bits (115), Expect = 1e-04
Identities = 35/134 (26%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C CNC+ ++ GS G C+ G C C+ Y+ + C C
Sbjct: 64 CVPCNCNGH---SNQCQDGS---GICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACP 115
Query: 695 CNLAGTLNSLGACNTKSG---QCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIG 751
C NS G C +G +C CK QC++C G++ C C C+
Sbjct: 116 CPHT---NSFGMCCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN 172
Query: 752 GSIDNNCDKTTGQC 765
G + +C TG C
Sbjct: 173 GQL-GSCHPLTGDC 185
Score = 48.4 bits (110), Expect = 5e-04
Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 16/122 (13%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGG--QCPCKPN 1364
C + + + C+E + + + R C C S + C GG +C CK
Sbjct: 83 CVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAG 140
Query: 1365 VIGRTCSACRTGYYGFP-----NCRPCHCPST---AICDD-NGMCIC--PKNVE-GENCD 1412
G C C GY+G P +C+PC C S C G CI PK+ E CD
Sbjct: 141 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECD 200
Query: 1413 RC 1414
C
Sbjct: 201 DC 202
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 6/85 (7%)
Query: 1738 CPRAYRGLSCEQCAEGHY-RLPSGFCVPCQC---NGHSDQCDVNTG-ICLNCADNTIGDH 1792
C G CE+C EG+Y G C C C N C VN G + +C G
Sbjct: 86 CQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFGMCCVVNGGDVRCSCKAGYTGTQ 145
Query: 1793 CEFCMSGYHGDATVGTPRDCLICAC 1817
CE C GY G+ C C+C
Sbjct: 146 CERCAPGYFGNPQ-KFGGSCQPCSC 169
>BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 184 bits (447), Expect = 7e-45
Identities = 162/568 (28%), Positives = 228/568 (40%), Gaps = 88/568 (15%)
Query: 227 IGGRCMCN-GH-ADTCEPADPAGNLNILVC-RCQ-HNTCGPQCNKCCSGFE-QKKWRISQ 281
+ G+C C G+ D C+ P G+ RC HN G QC+ E + ++ +
Sbjct: 286 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHN--GGQCSPTTGACECEPGYKGPR 343
Query: 282 NWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
+R E + T C D + +S + G C CQ G +CN+
Sbjct: 344 CQERLCPEGLHGPGCTLPCPCDAD---NTISC-----HPVTGAC-TCQPGWSGHHCNESC 394
Query: 342 PTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFD 399
P Y YG D CQ PC C + +C +G C C P F C+ SCA G +
Sbjct: 395 PVGY--YG------DGCQLPCTCQ---NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG 443
Query: 400 YPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKNCECNTVG 457
PNC C+CN GT C+P DG C CK + G C + C G + C N C
Sbjct: 444 -PNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNC-NESCTCAN 497
Query: 458 SVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC 516
+ C + G C+C + G TC C G + + C+C + CD V+G C
Sbjct: 498 GAA--CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADG----CDPVTGHC 551
Query: 517 ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C AG+ G RCD C G + V C+C+ GS S DG C C F G
Sbjct: 552 CCLAGWTGIRCDSTCPPGRW-----GPNCSVSCSCENGGSCSPE---DGSCECAPGFRGP 603
Query: 576 QCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C + C PG+Y + C V S C +G+C C F GA C+ C ++
Sbjct: 604 LCQRICPPGFYGHGCAQPCPLCVHSS--RPCHHISGICECLPGFSGALCNQVCAGGYFGQ 661
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCE 691
+ C+C G + G CQC G+ C+ C P +W P
Sbjct: 662 DCAQLCSCANNGTCSPIDGS--------CQCFPGWIGKDCSQACPPGFW-----GPACFH 708
Query: 692 QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDI 750
C+C ++ +C+ + G C C C Q C F+ V C C
Sbjct: 709 ACSC------HNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV-----CQCQN 757
Query: 751 GGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G S CD +G+C C + G+ C+Q
Sbjct: 758 GAS----CDHISGKCTCRTGFTGQHCEQ 781
Score = 160 bits (389), Expect = 8e-38
Identities = 128/438 (29%), Positives = 173/438 (39%), Gaps = 65/438 (14%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHC 418
PC CD +T +C +G C C+P + C+ SC GY+ PCTC NG + C
Sbjct: 361 PCPCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ-NGAD---C 415
Query: 419 TPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
G C C + G+ C + C G Y P C + C CN G+ C + G CTCK +
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT----CSPVDGSCTCKEGW 471
Query: 477 SGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGY 534
G C C +G + + C C C + G C C G+ G C+ C G
Sbjct: 472 QGLDCTLPCPSGTWGLNCNESCTCANGAA----CSPIDGSCSCTPGWLGDTCELPCPDGT 527
Query: 535 YMQVLGRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPDC-L 591
+ C + CDP G C CL + G +CD C PG + P+C +
Sbjct: 528 FGLNCSEHCDCSHADGCDPV---------TGHCCCLAGWTGIRCDSTCPPGRWG-PNCSV 577
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFA 650
SC+C+ GS ++G C C F G C C FY + + C P V +S
Sbjct: 578 SCSCENGGSCSP---EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPC---PLCVHSS-R 630
Query: 651 GCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGTLNSLGACN 708
C + +C+C G +CN C Y+ C Q C+C GT C+
Sbjct: 631 PCHHISG--ICECLPGFSGALCNQVCAGGYFGQD------CAQLCSCANNGT------CS 676
Query: 709 TKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G C C + C Q C GF+ C C G S C G CHC
Sbjct: 677 PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHA-----CSCHNGAS----CSAEDGACHC 727
Query: 768 HSRVEGRRCDQPIRAHYF 785
G C Q A +F
Sbjct: 728 TPGWTGLFCTQRCPAAFF 745
Score = 149 bits (362), Expect = 1e-34
Identities = 131/477 (27%), Positives = 181/477 (37%), Gaps = 74/477 (15%)
Query: 315 INGRYEGGGKCLNCQHNTEGINCNK-CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
++GR C +C+ G +C+ C ++ P+ CQC + C
Sbjct: 108 VHGRCVSPDTC-HCEPGWGGPDCSSGCDSDHWGPH--------CSNRCQCQ---NGALCN 155
Query: 374 EESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
+G C C F+ C CA G PC C G C P G C C Y
Sbjct: 156 PITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCR----HGASCDPRAGECLCAPGYT 211
Query: 433 GKSCE-ICEDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYY 489
G CE +C G + C+ C C G+ C +TG+C C ++G C Q C G +
Sbjct: 212 GVYCEELCPPGSHGAHCELRCPCQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTF 267
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVP- 547
+ C C G CD V+GQC C AG+ G RC ++C G + QC
Sbjct: 268 GQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFGSF------GFQCSQR 317
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDC-LSCNCDVSGSIGST 604
C+C G S + G C C + G +C + C G + P C L C CD +I S
Sbjct: 318 CDCHNGGQCSPT---TGACECEPGYKGPRCQERLCPEGLHG-PGCTLPCPCDADNTI-SC 372
Query: 605 CDDNGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
G C C+ + G C ++C +Y C C + A C S+ G C C
Sbjct: 373 HPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ------NGADCHSITGG--CTC 424
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
G +C + Y P C+CN GT C+ G C CK+
Sbjct: 425 APGFMGEVC----AVSCAAGTYGPNCSSICSCNNGGT------CSPVDGSCTCKEGWQGL 474
Query: 724 QCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C C G + L N+ C C G + C G C C G C+ P
Sbjct: 475 DCTLPCPSGTWGLNCNE-----SCTCANGAA----CSPIDGSCSCTPGWLGDTCELP 522
Score = 133 bits (321), Expect = 1e-29
Identities = 113/357 (31%), Positives = 136/357 (38%), Gaps = 48/357 (13%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C +RG CE+ CA G + G +PCQC H CD G CL CA G +CE
Sbjct: 161 CVCAAGFRGWRCEELCAPGTHG--KGCQLPCQCR-HGASCDPRAGECL-CAPGYTGVYCE 216
Query: 1795 -FCMSGYHGD--------ATVGTPRDCL-ICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
C G HG GT CACP + A C G S +C
Sbjct: 217 ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC- 275
Query: 1845 PGYGGARCEY------CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
P + G +C++ C AGY G + G + CS + + G C G C
Sbjct: 276 PCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSF--GFQCSQRCDCHNGGQCSPTTGAC 333
Query: 1899 LKCVNNTAGAACN--LCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVCRPGVIG 1955
+C G C LC G +G CT C CD C TG C C+PG G
Sbjct: 334 -ECEPGYKGPRCQERLCPEGLHGPG-----CTLPCPCDADNTISCHPVTGACTCQPGWSG 387
Query: 1956 EKCDRCAPDHWGLNTGLGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C+ P + G GC PC C C G C CA G G+ C CAAG
Sbjct: 388 HHCNESCPVGY---YGDGCQLPCTC---QNGADCHSITGGCTCAPGFMGEVCAVSCAAG- 440
Query: 2014 WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD-RCPE-RWVLIPQEGC 2068
Y + C+CN G G G C C G G C CP W L E C
Sbjct: 441 -TYGPNCSSICSCNNG---GTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC 493
Score = 132 bits (320), Expect = 2e-29
Identities = 110/333 (33%), Positives = 137/333 (41%), Gaps = 66/333 (19%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQCNGHSD-QCDVNTGICLNCADNTIGDH 1792
C+C Y+G C++ C EG + G +PC C+ + C TG C C G H
Sbjct: 333 CECEPGYKGPRCQERLCPEGLHG--PGCTLPCPCDADNTISCHPVTGAC-TCQPGWSGHH 389
Query: 1793 C-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C E C GY+GD C +P N A C G C C PG+ G
Sbjct: 390 CNESCPVGYYGDG------------CQLPCTCQNGA-DCHSITGG----CTCAPGFMGEV 432
Query: 1852 CEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C CAAG YG P NCS + + G+C ++G C C G C
Sbjct: 433 CAVSCAAGTYG--------------P-NCSSICSCNNGGTCSPVDGSCT-CKEGWQGLDC 476
Query: 1911 NL-CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
L C G +G NC +C C G A C G+C C PG +G+ C+ PD
Sbjct: 477 TLPCPSGTWG-----LNCNESCTCAN-GAA-CSPIDGSCSCTPGWLGDTCELPCPDG--- 526
Query: 1969 NTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCD-HCN 2025
GL C+ C+C S + CD G C C G TG +CD C G W C C+
Sbjct: 527 TFGLNCSEHCDC---SHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG---PNCSVSCS 580
Query: 2026 CNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
C G G G CEC PG G C R CP
Sbjct: 581 CENG---GSCSPEDGSCECAPGFRGPLCQRICP 610
Score = 131 bits (317), Expect = 4e-29
Identities = 109/371 (29%), Positives = 144/371 (38%), Gaps = 64/371 (17%)
Query: 227 IGGRCMCNGH--ADTCEPADPAGNLNILV---CRCQH-NTCGPQCNKCC-----SGFEQK 275
I G C C DTCE P G + C C H + C P CC +G
Sbjct: 504 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD 563
Query: 276 KWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGI 335
W C+C N + C+ PE G C C G
Sbjct: 564 STCPPGRWGPNCSVSCSCENGGS-CS--PE----------------DGSC-ECAPGFRGP 603
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CA 394
C + P + +G QPC H S+ C SG CEC P F C+ CA
Sbjct: 604 LCQRICPPGFYGHG-------CAQPCPLCVH-SSRPCHHISGICECLPGFSGALCNQVCA 655
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC-EICEDGYYSPECKN-CE 452
GYF + C+C NGT C+P DG C C + GK C + C G++ P C + C
Sbjct: 656 GGYFGQDCAQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACS 711
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDD 511
C+ S C G C C ++G C Q C A ++ + C C + CD
Sbjct: 712 CHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGAS----CDH 763
Query: 512 VSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLT 570
+SG+C C+ GF G C+Q C G + G ++ C N ST G C C
Sbjct: 764 ISGKCTCRTGFTGQHCEQRCAPGTFGY--GCQQLCECMN------NSTCDHVTGTCYCSP 815
Query: 571 NFGGAQCDQCS 581
F G +CDQ +
Sbjct: 816 GFKGIRCDQAA 826
Score = 126 bits (304), Expect = 2e-27
Identities = 104/328 (31%), Positives = 140/328 (42%), Gaps = 62/328 (18%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHC 1793
C C + G+ C+ C G R V C C NG S C G C CA G C
Sbjct: 551 CCCLAGWTGIRCDSTCPPG--RWGPNCSVSCSCENGGS--CSPEDGSC-ECAPGFRGPLC 605
Query: 1794 E-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G++G G + C +C P ++ + C+ C PG+ GA C
Sbjct: 606 QRICPPGFYGH---GCAQPCPLCV-HSSRPCHHISGICE-----------CLPGFSGALC 650
Query: 1853 -EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
+ CA GY+G D + C+C+ N G+C I+G C +C G C+
Sbjct: 651 NQVCAGGYFG---------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDCS 694
Query: 1912 -LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLN 1969
C PGF+G A F AC C A C + G C C PG G C RC +G +
Sbjct: 695 QACPPGFWGPACFH----ACSCHNG--ASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD 748
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDH-CNCN 2027
G C C G + CD +G+C C G TG+ C+Q CA G + Y GC C C
Sbjct: 749 CGRVCQ-CQNGAS-----CDHISGKCTCRTGFTGQHCEQRCAPGTFGY---GCQQLCECM 799
Query: 2028 TGYSVGFMCNATGQCECLPGVIGEKCDR 2055
+ + TG C C PG G +CD+
Sbjct: 800 NNSTCD---HVTGTCYCSPGFKGIRCDQ 824
Score = 121 bits (291), Expect = 6e-26
Identities = 104/352 (29%), Positives = 134/352 (38%), Gaps = 57/352 (16%)
Query: 1735 ECQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQ----CNGHSDQCDVNTG----ICLN-C 1784
EC C Y G+ CE+ C G + PCQ C+ + +C G +C C
Sbjct: 203 ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPC 262
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICA------CPMPYPSNNFALSCDL---SEN 1835
T G +C +HG C A C P +F C N
Sbjct: 263 PPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHN 322
Query: 1836 GSLIS-----CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS 1890
G S C C+PGY G RC+ PE LH PC C + + S
Sbjct: 323 GGQCSPTTGACECEPGYKGPRCQERLC-----PE--GLHGPGCTLPCPCDAD----NTIS 371
Query: 1891 CDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C + G C C +G CN C G+YGD C C ADC S TG C C
Sbjct: 372 CHPVTGAC-TCQPGWSGHHCNESCPVGYYGDGC----QLPCTCQ--NGADCHSITGGCTC 424
Query: 1950 RPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD- 2007
PG +GE C CA +G N C+ CN G C +G C C +G G C
Sbjct: 425 APGFMGEVCAVSCAAGTYGPNCSSICS-CNNG-----GTCSPVDGSCTCKEGWQGLDCTL 478
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD-RCPE 2058
C +G W + + C C G + G C C PG +G+ C+ CP+
Sbjct: 479 PCPSGTWGLNCN--ESCTCANGAACS---PIDGSCSCTPGWLGDTCELPCPD 525
Score = 105 bits (252), Expect = 3e-21
Identities = 84/252 (33%), Positives = 113/252 (44%), Gaps = 45/252 (17%)
Query: 1817 CPMPYPSNNFALSCDLSE--NGSLIS---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTG 1871
CP Y + +F + E +G +S C+C+PG+GG C ++G D+D H G
Sbjct: 89 CPGYYENGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDC---SSGC-----DSD-HWG 139
Query: 1872 DYCKP-CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNC-T 1928
+C C C Q+ C+ I G C+ C G C LCAPG +G K C
Sbjct: 140 PHCSNRCQC------QNGALCNPITGACV-CAAGFRGWRCEELCAPGTHG-----KGCQL 187
Query: 1929 ACICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQ 1987
C C G A CD G C+C PG G C+ C P G + L C PC G
Sbjct: 188 PCQC-RHG-ASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRC-PCQNG-----GT 239
Query: 1988 CDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLP 2046
C G+C C G TG C Q C G + ++ C C+ G G + TGQC C
Sbjct: 240 CHHITGECACPPGWTGAVCAQPCPPG--TFGQNCSQDCPCHHG---GQCDHVTGQCHCTA 294
Query: 2047 GVIGEKC-DRCP 2057
G +G++C + CP
Sbjct: 295 GYMGDRCQEECP 306
Score = 101 bits (241), Expect = 6e-20
Identities = 85/324 (26%), Positives = 127/324 (39%), Gaps = 50/324 (15%)
Query: 470 CTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C C+ + G C+ C + ++ C C ++C+ ++G C+C AGF G RC+
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNG----ALCNPITGACVCAAGFRGWRCE 173
Query: 529 Q-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYK 586
+ C G + G+ Q +PC C S G+C C + G C++ C PG +
Sbjct: 174 ELCAPGTH----GKGCQ-LPCQCRHGASCDPRA---GECLCAPGYTGVYCEELCPPGSHG 225
Query: 587 YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRG 644
L C C G TC G C C + GA C C + ++C C G
Sbjct: 226 AHCELRCPCQNGG----TCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 281
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
C V G+ C C G C QE PFG C+ ++
Sbjct: 282 Q------CDHV-TGQ-CHCTAGYMGDRC----------QEECPFGSFGFQCSQRCDCHNG 323
Query: 705 GACNTKSGQCVCKQHVGERQCDQ--CLDGFYRLQTNDVFGCT-ECDCDIGGSIDNNCDKT 761
G C+ +G C C+ +C + C +G + GCT C CD +I +C
Sbjct: 324 GQCSPTTGACECEPGYKGPRCQERLCPEGLHGP------GCTLPCPCDADNTI--SCHPV 375
Query: 762 TGQCHCHSRVEGRRCDQPIRAHYF 785
TG C C G C++ Y+
Sbjct: 376 TGACTCQPGWSGHHCNESCPVGYY 399
Score = 99.1 bits (236), Expect = 3e-19
Identities = 88/281 (31%), Positives = 117/281 (41%), Gaps = 54/281 (19%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQ-CDVNTGICLNCADNTIGDHC 1793
C+C +RG C++ C G Y G PC HS + C +GIC C G C
Sbjct: 594 CECAPGFRGPLCQRICPPGFYG--HGCAQPCPLCVHSSRPCHHISGIC-ECLPGFSGALC 650
Query: 1794 -EFCMSGYHGDATVGTPRDCL-ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
+ C GY G +DC +C+C +NN +C + SC C PG+ G
Sbjct: 651 NQVCAGGYFG-------QDCAQLCSC-----ANNG--TCSPIDG----SCQCFPGWIGKD 692
Query: 1852 C-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C + C G++G H C+C SC + +G C C G C
Sbjct: 693 CSQACPPGFWG---PACFHA------CSCHNG------ASCSAEDGAC-HCTPGWTGLFC 736
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCD-RCAPDHWGLN 1969
P A F K+C +C A CD +G C CR G G+ C+ RCAP +G
Sbjct: 737 TQRCPA----AFFGKDCGR-VCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY- 790
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
GC C + ST CD G C C+ G G +CDQ A
Sbjct: 791 ---GCQQL-CECMNNST-CDHVTGTCYCSPGFKGIRCDQAA 826
Score = 91.5 bits (217), Expect = 5e-17
Identities = 62/179 (34%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAIC 1394
A+ C C G+ C+ G C C P IG+ CS AC G++G P C C C + A C
Sbjct: 664 AQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWG-PACFHACSCHNGASC 718
Query: 1395 D-DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
++G C C G C RC F D R C C N C+ SGKC
Sbjct: 719 SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQ------NGASCDHISGKCT 769
Query: 1453 CRENVRGRVCDH-CVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
CR G+ C+ C PG + + C Q C C + T CD T CYC +G CD
Sbjct: 770 CRTGFTGQHCEQRCAPGTFGY-GCQQLCECMNNST----CDHVTGTCYCSPGFKGIRCD 823
Score = 78.6 bits (185), Expect = 4e-13
Identities = 55/185 (29%), Positives = 71/185 (38%), Gaps = 23/185 (12%)
Query: 1333 YNSGAR-PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCP 1389
Y G + PC C +C++ G C C P +G C+ +C G YG PNC C C
Sbjct: 399 YGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCN 453
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADS 1448
+ C +G C C + +G +C P G NCN N C
Sbjct: 454 NGGTCSPVDGSCTCKEGWQGLDCTLPCP--------SGTWGLNCNESCTCANGAACSPID 505
Query: 1449 GKCACRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
G C+C G C+ C G + C C+ H D CD T C C G
Sbjct: 506 GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS-HA---DGCDPVTGHCCCLAGWTGIR 561
Query: 1508 CD-TC 1511
CD TC
Sbjct: 562 CDSTC 566
Score = 73.7 bits (173), Expect = 1e-11
Identities = 56/195 (28%), Positives = 71/195 (36%), Gaps = 22/195 (11%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD- 1396
PC CD + C+ G C C+P G C+ +C GYYG PC C + A C
Sbjct: 361 PCPCD--ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI 418
Query: 1397 NGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACR 1454
G C C GE C C T+ C C+CN G C G C C+
Sbjct: 419 TGGCTCAPGFMGEVCAVSCAAGTYG----PNCSSICSCNNGGT------CSPVDGSCTCK 468
Query: 1455 ENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCK 1512
E +G C C G + CTC +G C C C G C+ C
Sbjct: 469 EGWQGLDCTLPCPSGTWGLNCNESCTC-ANGA---ACSPIDGSCSCTPGWLGDTCELPCP 524
Query: 1513 EEYFNLQDDNPDGCT 1527
+ F L C+
Sbjct: 525 DGTFGLNCSEHCDCS 539
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/183 (28%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1333 YNSG-ARPC-LCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCP 1389
Y G A+PC LC + C+ G C C P G C+ C GY+G + C C
Sbjct: 614 YGHGCAQPCPLCVH---SSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCA 670
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEAD 1447
+ C +G C C G++C + P F C C+C+ N C A+
Sbjct: 671 NNGTCSPIDGSCQCFPGWIGKDCSQACPPGF---WGPACFHACSCH------NGASCSAE 721
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
G C C G C P + DC + C C ++G + CD + +C C+T GQ
Sbjct: 722 DGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQC-QNGAS---CDHISGKCTCRTGFTGQ 777
Query: 1507 ACD 1509
C+
Sbjct: 778 HCE 780
Score = 71.7 bits (168), Expect = 5e-11
Identities = 51/167 (30%), Positives = 62/167 (37%), Gaps = 20/167 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEGE 1409
CN G C C G C C G +G PC C A CD G C+C G
Sbjct: 154 CNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGV 213
Query: 1410 NCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVP 1467
C+ C P + + C C G C +G+CAC G VC C P
Sbjct: 214 YCEELCPPGSHGAHCELRCP---CQNGGT------CHHITGECACPPGWTGAVCAQPCPP 264
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
G + C C+ G CD T QC+C G D C+EE
Sbjct: 265 GTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMG---DRCQEE 304
Score = 67.3 bits (157), Expect = 1e-09
Identities = 48/171 (28%), Positives = 58/171 (33%), Gaps = 18/171 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G C C P +G TC C G +G C C CD G C C G
Sbjct: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560
Query: 1410 NCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CV 1466
CD C P + C C+C G C + G C C RG +C C
Sbjct: 561 RCDSTCPPGRWG----PNCSVSCSCENGG------SCSPEDGSCECAPGFRGPLCQRICP 610
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYF 1516
PG Y C H + C + C C G C+ C YF
Sbjct: 611 PGFYGHGCAQPCPLCVHSSR--PCHHISGICECLPGFSGALCNQVCAGGYF 659
Score = 64.5 bits (150), Expect = 7e-09
Identities = 62/228 (27%), Positives = 86/228 (37%), Gaps = 39/228 (17%)
Query: 579 QCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE-- 636
QC PGYY+ D C + C CHC+ + G C + + + P C
Sbjct: 87 QCCPGYYENGDFCIPLC-TEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 637 -ECN----CDP-RGVTASFAG---------CGSVPAGELCQ--CKDRVQGRICND----- 674
+C C+P G AG C G+ CQ C+ R G C+
Sbjct: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCR-HGASCDPRAGEC 204
Query: 675 -CKPLYWNL--QEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLD 730
C P Y + +E P G +C L + G C+ +G+C C C Q C
Sbjct: 205 LCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPP 264
Query: 731 GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G + + +C C GG CD TGQCHC + G RC +
Sbjct: 265 GTFGQNCSQ-----DCPCHHGG----QCDHVTGQCHCTAGYMGDRCQE 303
Score = 64.5 bits (150), Expect = 7e-09
Identities = 45/163 (27%), Positives = 63/163 (38%), Gaps = 16/163 (9%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEG 1408
+C+ GQC C +G C C G +GF + C C + C G C C +G
Sbjct: 282 QCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACECEPGYKG 341
Query: 1409 ENC-DRCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHC 1465
C +R P + GC C C+ N + C +G C C+ G C + C
Sbjct: 342 PRCQERLCPEGLHGP---GCTLPCPCD----ADNTISCHPVTGACTCQPGWSGHHCNESC 394
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+Y CTC ++G C T C C G+ C
Sbjct: 395 PVGYYGDGCQLPCTC-QNGAD---CHSITGGCTCAPGFMGEVC 433
Score = 50.8 bits (116), Expect = 9e-05
Identities = 42/148 (28%), Positives = 56/148 (37%), Gaps = 20/148 (13%)
Query: 1368 RTCSACRTGYYGFPN-CRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
R S C GYY + C P C + +G C+ P + C C+P D G
Sbjct: 83 RRRSQCCPGYYENGDFCIPL-CTEECV---HGRCVSP-----DTC-HCEPGWGGPDCSSG 132
Query: 1427 CDDCN----CNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVPGHYAFPDCYQCTCN 1481
CD + C+ N C +G C C RG C+ C PG + C C
Sbjct: 133 CDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQC- 191
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
RHG + CD +C C G C+
Sbjct: 192 RHGAS---CDPRAGECLCAPGYTGVYCE 216
>BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 184 bits (447), Expect = 7e-45
Identities = 162/568 (28%), Positives = 228/568 (40%), Gaps = 88/568 (15%)
Query: 227 IGGRCMCN-GH-ADTCEPADPAGNLNILVC-RCQ-HNTCGPQCNKCCSGFE-QKKWRISQ 281
+ G+C C G+ D C+ P G+ RC HN G QC+ E + ++ +
Sbjct: 286 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHN--GGQCSPTTGACECEPGYKGPR 343
Query: 282 NWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
+R E + T C D + +S + G C CQ G +CN+
Sbjct: 344 CQERLCPEGLHGPGCTLPCPCDAD---NTISC-----HPVTGAC-TCQPGWSGHHCNESC 394
Query: 342 PTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFD 399
P Y YG D CQ PC C + +C +G C C P F C+ SCA G +
Sbjct: 395 PVGY--YG------DGCQLPCTCQ---NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG 443
Query: 400 YPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKNCECNTVG 457
PNC C+CN GT C+P DG C CK + G C + C G + C N C
Sbjct: 444 -PNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNC-NESCTCAN 497
Query: 458 SVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC 516
+ C + G C+C + G TC C G + + C+C + CD V+G C
Sbjct: 498 GAA--CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADG----CDPVTGHC 551
Query: 517 ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C AG+ G RCD C G + V C+C+ GS S DG C C F G
Sbjct: 552 CCLAGWTGIRCDSTCPPGRW-----GPNCSVSCSCENGGSCSPE---DGSCECAPGFRGP 603
Query: 576 QCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C + C PG+Y + C V S C +G+C C F GA C+ C ++
Sbjct: 604 LCQRICPPGFYGHGCAQPCPLCVHSS--RPCHHISGICECLPGFSGALCNQVCAGGYFGQ 661
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCE 691
+ C+C G + G CQC G+ C+ C P +W P
Sbjct: 662 DCAQLCSCANNGTCSPIDGS--------CQCFPGWIGKDCSQACPPGFW-----GPACFH 708
Query: 692 QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDI 750
C+C ++ +C+ + G C C C Q C F+ V C C
Sbjct: 709 ACSC------HNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV-----CQCQN 757
Query: 751 GGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G S CD +G+C C + G+ C+Q
Sbjct: 758 GAS----CDHISGKCTCRTGFTGQHCEQ 781
Score = 160 bits (389), Expect = 8e-38
Identities = 128/438 (29%), Positives = 173/438 (39%), Gaps = 65/438 (14%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHC 418
PC CD +T +C +G C C+P + C+ SC GY+ PCTC NG + C
Sbjct: 361 PCPCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ-NGAD---C 415
Query: 419 TPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
G C C + G+ C + C G Y P C + C CN G+ C + G CTCK +
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT----CSPVDGSCTCKEGW 471
Query: 477 SGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGY 534
G C C +G + + C C C + G C C G+ G C+ C G
Sbjct: 472 QGLDCTLPCPSGTWGLNCNESCTCANGAA----CSPIDGSCSCTPGWLGDTCELPCPDGT 527
Query: 535 YMQVLGRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPDC-L 591
+ C + CDP G C CL + G +CD C PG + P+C +
Sbjct: 528 FGLNCSEHCDCSHADGCDPV---------TGHCCCLAGWTGIRCDSTCPPGRWG-PNCSV 577
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFA 650
SC+C+ GS ++G C C F G C C FY + + C P V +S
Sbjct: 578 SCSCENGGSCSP---EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPC---PLCVHSS-R 630
Query: 651 GCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGTLNSLGACN 708
C + +C+C G +CN C Y+ C Q C+C GT C+
Sbjct: 631 PCHHISG--ICECLPGFSGALCNQVCAGGYFGQD------CAQLCSCANNGT------CS 676
Query: 709 TKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G C C + C Q C GF+ C C G S C G CHC
Sbjct: 677 PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHA-----CSCHNGAS----CSAEDGACHC 727
Query: 768 HSRVEGRRCDQPIRAHYF 785
G C Q A +F
Sbjct: 728 TPGWTGLFCTQRCPAAFF 745
Score = 149 bits (362), Expect = 1e-34
Identities = 131/477 (27%), Positives = 181/477 (37%), Gaps = 74/477 (15%)
Query: 315 INGRYEGGGKCLNCQHNTEGINCNK-CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
++GR C +C+ G +C+ C ++ P+ CQC + C
Sbjct: 108 VHGRCVSPDTC-HCEPGWGGPDCSSGCDSDHWGPH--------CSNRCQCQ---NGALCN 155
Query: 374 EESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
+G C C F+ C CA G PC C G C P G C C Y
Sbjct: 156 PITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCR----HGASCDPRAGECLCAPGYT 211
Query: 433 GKSCE-ICEDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYY 489
G CE +C G + C+ C C G+ C +TG+C C ++G C Q C G +
Sbjct: 212 GVYCEELCPPGSHGAHCELRCPCQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTF 267
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVP- 547
+ C C G CD V+GQC C AG+ G RC ++C G + QC
Sbjct: 268 GQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFGSF------GFQCSQR 317
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDC-LSCNCDVSGSIGST 604
C+C G S + G C C + G +C + C G + P C L C CD +I S
Sbjct: 318 CDCHNGGQCSPT---TGACECEPGYKGPRCQERLCPEGLHG-PGCTLPCPCDADNTI-SC 372
Query: 605 CDDNGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
G C C+ + G C ++C +Y C C + A C S+ G C C
Sbjct: 373 HPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ------NGADCHSITGG--CTC 424
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
G +C + Y P C+CN GT C+ G C CK+
Sbjct: 425 APGFMGEVC----AVSCAAGTYGPNCSSICSCNNGGT------CSPVDGSCTCKEGWQGL 474
Query: 724 QCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C C G + L N+ C C G + C G C C G C+ P
Sbjct: 475 DCTLPCPSGTWGLNCNE-----SCTCANGAA----CSPIDGSCSCTPGWLGDTCELP 522
Score = 133 bits (321), Expect = 1e-29
Identities = 113/357 (31%), Positives = 136/357 (38%), Gaps = 48/357 (13%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C +RG CE+ CA G + G +PCQC H CD G CL CA G +CE
Sbjct: 161 CVCAAGFRGWRCEELCAPGTHG--KGCQLPCQCR-HGASCDPRAGECL-CAPGYTGVYCE 216
Query: 1795 -FCMSGYHGD--------ATVGTPRDCL-ICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
C G HG GT CACP + A C G S +C
Sbjct: 217 ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC- 275
Query: 1845 PGYGGARCEY------CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
P + G +C++ C AGY G + G + CS + + G C G C
Sbjct: 276 PCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSF--GFQCSQRCDCHNGGQCSPTTGAC 333
Query: 1899 LKCVNNTAGAACN--LCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVCRPGVIG 1955
+C G C LC G +G CT C CD C TG C C+PG G
Sbjct: 334 -ECEPGYKGPRCQERLCPEGLHGPG-----CTLPCPCDADNTISCHPVTGACTCQPGWSG 387
Query: 1956 EKCDRCAPDHWGLNTGLGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C+ P + G GC PC C C G C CA G G+ C CAAG
Sbjct: 388 HHCNESCPVGY---YGDGCQLPCTC---QNGADCHSITGGCTCAPGFMGEVCAVSCAAG- 440
Query: 2014 WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD-RCPE-RWVLIPQEGC 2068
Y + C+CN G G G C C G G C CP W L E C
Sbjct: 441 -TYGPNCSSICSCNNG---GTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC 493
Score = 132 bits (320), Expect = 2e-29
Identities = 110/333 (33%), Positives = 137/333 (41%), Gaps = 66/333 (19%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQCNGHSD-QCDVNTGICLNCADNTIGDH 1792
C+C Y+G C++ C EG + G +PC C+ + C TG C C G H
Sbjct: 333 CECEPGYKGPRCQERLCPEGLHG--PGCTLPCPCDADNTISCHPVTGAC-TCQPGWSGHH 389
Query: 1793 C-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C E C GY+GD C +P N A C G C C PG+ G
Sbjct: 390 CNESCPVGYYGDG------------CQLPCTCQNGA-DCHSITGG----CTCAPGFMGEV 432
Query: 1852 CEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C CAAG YG P NCS + + G+C ++G C C G C
Sbjct: 433 CAVSCAAGTYG--------------P-NCSSICSCNNGGTCSPVDGSCT-CKEGWQGLDC 476
Query: 1911 NL-CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
L C G +G NC +C C G A C G+C C PG +G+ C+ PD
Sbjct: 477 TLPCPSGTWG-----LNCNESCTCAN-GAA-CSPIDGSCSCTPGWLGDTCELPCPDG--- 526
Query: 1969 NTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCD-HCN 2025
GL C+ C+C S + CD G C C G TG +CD C G W C C+
Sbjct: 527 TFGLNCSEHCDC---SHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG---PNCSVSCS 580
Query: 2026 CNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
C G G G CEC PG G C R CP
Sbjct: 581 CENG---GSCSPEDGSCECAPGFRGPLCQRICP 610
Score = 131 bits (317), Expect = 4e-29
Identities = 109/371 (29%), Positives = 144/371 (38%), Gaps = 64/371 (17%)
Query: 227 IGGRCMCNGH--ADTCEPADPAGNLNILV---CRCQH-NTCGPQCNKCC-----SGFEQK 275
I G C C DTCE P G + C C H + C P CC +G
Sbjct: 504 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD 563
Query: 276 KWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGI 335
W C+C N + C+ PE G C C G
Sbjct: 564 STCPPGRWGPNCSVSCSCENGGS-CS--PE----------------DGSC-ECAPGFRGP 603
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CA 394
C + P + +G QPC H S+ C SG CEC P F C+ CA
Sbjct: 604 LCQRICPPGFYGHG-------CAQPCPLCVH-SSRPCHHISGICECLPGFSGALCNQVCA 655
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC-EICEDGYYSPECKN-CE 452
GYF + C+C NGT C+P DG C C + GK C + C G++ P C + C
Sbjct: 656 GGYFGQDCAQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACS 711
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDD 511
C+ S C G C C ++G C Q C A ++ + C C + CD
Sbjct: 712 CHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGAS----CDH 763
Query: 512 VSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLT 570
+SG+C C+ GF G C+Q C G + G ++ C N ST G C C
Sbjct: 764 ISGKCTCRTGFTGQHCEQRCAPGTFGY--GCQQLCECMN------NSTCDHVTGTCYCSP 815
Query: 571 NFGGAQCDQCS 581
F G +CDQ +
Sbjct: 816 GFKGIRCDQAA 826
Score = 126 bits (304), Expect = 2e-27
Identities = 104/328 (31%), Positives = 140/328 (42%), Gaps = 62/328 (18%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHC 1793
C C + G+ C+ C G R V C C NG S C G C CA G C
Sbjct: 551 CCCLAGWTGIRCDSTCPPG--RWGPNCSVSCSCENGGS--CSPEDGSC-ECAPGFRGPLC 605
Query: 1794 E-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G++G G + C +C P ++ + C+ C PG+ GA C
Sbjct: 606 QRICPPGFYGH---GCAQPCPLCV-HSSRPCHHISGICE-----------CLPGFSGALC 650
Query: 1853 -EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
+ CA GY+G D + C+C+ N G+C I+G C +C G C+
Sbjct: 651 NQVCAGGYFG---------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDCS 694
Query: 1912 -LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLN 1969
C PGF+G A F AC C A C + G C C PG G C RC +G +
Sbjct: 695 QACPPGFWGPACFH----ACSCHNG--ASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD 748
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDH-CNCN 2027
G C C G + CD +G+C C G TG+ C+Q CA G + Y GC C C
Sbjct: 749 CGRVCQ-CQNGAS-----CDHISGKCTCRTGFTGQHCEQRCAPGTFGY---GCQQLCECM 799
Query: 2028 TGYSVGFMCNATGQCECLPGVIGEKCDR 2055
+ + TG C C PG G +CD+
Sbjct: 800 NNSTCD---HVTGTCYCSPGFKGIRCDQ 824
Score = 121 bits (291), Expect = 6e-26
Identities = 104/352 (29%), Positives = 134/352 (38%), Gaps = 57/352 (16%)
Query: 1735 ECQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQ----CNGHSDQCDVNTG----ICLN-C 1784
EC C Y G+ CE+ C G + PCQ C+ + +C G +C C
Sbjct: 203 ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPC 262
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICA------CPMPYPSNNFALSCDL---SEN 1835
T G +C +HG C A C P +F C N
Sbjct: 263 PPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHN 322
Query: 1836 GSLIS-----CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS 1890
G S C C+PGY G RC+ PE LH PC C + + S
Sbjct: 323 GGQCSPTTGACECEPGYKGPRCQERLC-----PE--GLHGPGCTLPCPCDAD----NTIS 371
Query: 1891 CDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C + G C C +G CN C G+YGD C C ADC S TG C C
Sbjct: 372 CHPVTGAC-TCQPGWSGHHCNESCPVGYYGDGC----QLPCTCQ--NGADCHSITGGCTC 424
Query: 1950 RPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD- 2007
PG +GE C CA +G N C+ CN G C +G C C +G G C
Sbjct: 425 APGFMGEVCAVSCAAGTYGPNCSSICS-CNNG-----GTCSPVDGSCTCKEGWQGLDCTL 478
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD-RCPE 2058
C +G W + + C C G + G C C PG +G+ C+ CP+
Sbjct: 479 PCPSGTWGLNCN--ESCTCANGAACS---PIDGSCSCTPGWLGDTCELPCPD 525
Score = 105 bits (252), Expect = 3e-21
Identities = 84/252 (33%), Positives = 113/252 (44%), Gaps = 45/252 (17%)
Query: 1817 CPMPYPSNNFALSCDLSE--NGSLIS---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTG 1871
CP Y + +F + E +G +S C+C+PG+GG C ++G D+D H G
Sbjct: 89 CPGYYENGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDC---SSGC-----DSD-HWG 139
Query: 1872 DYCKP-CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNC-T 1928
+C C C Q+ C+ I G C+ C G C LCAPG +G K C
Sbjct: 140 PHCSNRCQC------QNGALCNPITGACV-CAAGFRGWRCEELCAPGTHG-----KGCQL 187
Query: 1929 ACICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQ 1987
C C G A CD G C+C PG G C+ C P G + L C PC G
Sbjct: 188 PCQC-RHG-ASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRC-PCQNG-----GT 239
Query: 1988 CDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLP 2046
C G+C C G TG C Q C G + ++ C C+ G G + TGQC C
Sbjct: 240 CHHITGECACPPGWTGAVCAQPCPPG--TFGQNCSQDCPCHHG---GQCDHVTGQCHCTA 294
Query: 2047 GVIGEKC-DRCP 2057
G +G++C + CP
Sbjct: 295 GYMGDRCQEECP 306
Score = 101 bits (241), Expect = 6e-20
Identities = 85/324 (26%), Positives = 127/324 (39%), Gaps = 50/324 (15%)
Query: 470 CTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C C+ + G C+ C + ++ C C ++C+ ++G C+C AGF G RC+
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNG----ALCNPITGACVCAAGFRGWRCE 173
Query: 529 Q-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYK 586
+ C G + G+ Q +PC C S G+C C + G C++ C PG +
Sbjct: 174 ELCAPGTH----GKGCQ-LPCQCRHGASCDPRA---GECLCAPGYTGVYCEELCPPGSHG 225
Query: 587 YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRG 644
L C C G TC G C C + GA C C + ++C C G
Sbjct: 226 AHCELRCPCQNGG----TCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 281
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
C V G+ C C G C QE PFG C+ ++
Sbjct: 282 Q------CDHV-TGQ-CHCTAGYMGDRC----------QEECPFGSFGFQCSQRCDCHNG 323
Query: 705 GACNTKSGQCVCKQHVGERQCDQ--CLDGFYRLQTNDVFGCT-ECDCDIGGSIDNNCDKT 761
G C+ +G C C+ +C + C +G + GCT C CD +I +C
Sbjct: 324 GQCSPTTGACECEPGYKGPRCQERLCPEGLHGP------GCTLPCPCDADNTI--SCHPV 375
Query: 762 TGQCHCHSRVEGRRCDQPIRAHYF 785
TG C C G C++ Y+
Sbjct: 376 TGACTCQPGWSGHHCNESCPVGYY 399
Score = 99.1 bits (236), Expect = 3e-19
Identities = 88/281 (31%), Positives = 117/281 (41%), Gaps = 54/281 (19%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQ-CDVNTGICLNCADNTIGDHC 1793
C+C +RG C++ C G Y G PC HS + C +GIC C G C
Sbjct: 594 CECAPGFRGPLCQRICPPGFYG--HGCAQPCPLCVHSSRPCHHISGIC-ECLPGFSGALC 650
Query: 1794 -EFCMSGYHGDATVGTPRDCL-ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
+ C GY G +DC +C+C +NN +C + SC C PG+ G
Sbjct: 651 NQVCAGGYFG-------QDCAQLCSC-----ANNG--TCSPIDG----SCQCFPGWIGKD 692
Query: 1852 C-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C + C G++G H C+C SC + +G C C G C
Sbjct: 693 CSQACPPGFWG---PACFHA------CSCHNG------ASCSAEDGAC-HCTPGWTGLFC 736
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCD-RCAPDHWGLN 1969
P A F K+C +C A CD +G C CR G G+ C+ RCAP +G
Sbjct: 737 TQRCPA----AFFGKDCGR-VCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY- 790
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
GC C + ST CD G C C+ G G +CDQ A
Sbjct: 791 ---GCQQL-CECMNNST-CDHVTGTCYCSPGFKGIRCDQAA 826
Score = 91.5 bits (217), Expect = 5e-17
Identities = 62/179 (34%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAIC 1394
A+ C C G+ C+ G C C P IG+ CS AC G++G P C C C + A C
Sbjct: 664 AQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWG-PACFHACSCHNGASC 718
Query: 1395 D-DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
++G C C G C RC F D R C C N C+ SGKC
Sbjct: 719 SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQ------NGASCDHISGKCT 769
Query: 1453 CRENVRGRVCDH-CVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
CR G+ C+ C PG + + C Q C C + T CD T CYC +G CD
Sbjct: 770 CRTGFTGQHCEQRCAPGTFGY-GCQQLCECMNNST----CDHVTGTCYCSPGFKGIRCD 823
Score = 78.6 bits (185), Expect = 4e-13
Identities = 55/185 (29%), Positives = 71/185 (38%), Gaps = 23/185 (12%)
Query: 1333 YNSGAR-PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCP 1389
Y G + PC C +C++ G C C P +G C+ +C G YG PNC C C
Sbjct: 399 YGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCN 453
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADS 1448
+ C +G C C + +G +C P G NCN N C
Sbjct: 454 NGGTCSPVDGSCTCKEGWQGLDCTLPCP--------SGTWGLNCNESCTCANGAACSPID 505
Query: 1449 GKCACRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
G C+C G C+ C G + C C+ H D CD T C C G
Sbjct: 506 GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS-HA---DGCDPVTGHCCCLAGWTGIR 561
Query: 1508 CD-TC 1511
CD TC
Sbjct: 562 CDSTC 566
Score = 73.7 bits (173), Expect = 1e-11
Identities = 56/195 (28%), Positives = 71/195 (36%), Gaps = 22/195 (11%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD- 1396
PC CD + C+ G C C+P G C+ +C GYYG PC C + A C
Sbjct: 361 PCPCD--ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI 418
Query: 1397 NGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACR 1454
G C C GE C C T+ C C+CN G C G C C+
Sbjct: 419 TGGCTCAPGFMGEVCAVSCAAGTYG----PNCSSICSCNNGGT------CSPVDGSCTCK 468
Query: 1455 ENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCK 1512
E +G C C G + CTC +G C C C G C+ C
Sbjct: 469 EGWQGLDCTLPCPSGTWGLNCNESCTC-ANGA---ACSPIDGSCSCTPGWLGDTCELPCP 524
Query: 1513 EEYFNLQDDNPDGCT 1527
+ F L C+
Sbjct: 525 DGTFGLNCSEHCDCS 539
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/183 (28%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1333 YNSG-ARPC-LCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCP 1389
Y G A+PC LC + C+ G C C P G C+ C GY+G + C C
Sbjct: 614 YGHGCAQPCPLCVH---SSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCA 670
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEAD 1447
+ C +G C C G++C + P F C C+C+ N C A+
Sbjct: 671 NNGTCSPIDGSCQCFPGWIGKDCSQACPPGF---WGPACFHACSCH------NGASCSAE 721
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
G C C G C P + DC + C C ++G + CD + +C C+T GQ
Sbjct: 722 DGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQC-QNGAS---CDHISGKCTCRTGFTGQ 777
Query: 1507 ACD 1509
C+
Sbjct: 778 HCE 780
Score = 71.7 bits (168), Expect = 5e-11
Identities = 51/167 (30%), Positives = 62/167 (37%), Gaps = 20/167 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEGE 1409
CN G C C G C C G +G PC C A CD G C+C G
Sbjct: 154 CNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGV 213
Query: 1410 NCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVP 1467
C+ C P + + C C G C +G+CAC G VC C P
Sbjct: 214 YCEELCPPGSHGAHCELRCP---CQNGGT------CHHITGECACPPGWTGAVCAQPCPP 264
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
G + C C+ G CD T QC+C G D C+EE
Sbjct: 265 GTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMG---DRCQEE 304
Score = 67.3 bits (157), Expect = 1e-09
Identities = 48/171 (28%), Positives = 58/171 (33%), Gaps = 18/171 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G C C P +G TC C G +G C C CD G C C G
Sbjct: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560
Query: 1410 NCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CV 1466
CD C P + C C+C G C + G C C RG +C C
Sbjct: 561 RCDSTCPPGRWG----PNCSVSCSCENGG------SCSPEDGSCECAPGFRGPLCQRICP 610
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYF 1516
PG Y C H + C + C C G C+ C YF
Sbjct: 611 PGFYGHGCAQPCPLCVHSSR--PCHHISGICECLPGFSGALCNQVCAGGYF 659
Score = 64.5 bits (150), Expect = 7e-09
Identities = 62/228 (27%), Positives = 86/228 (37%), Gaps = 39/228 (17%)
Query: 579 QCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE-- 636
QC PGYY+ D C + C CHC+ + G C + + + P C
Sbjct: 87 QCCPGYYENGDFCIPLC-TEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 637 -ECN----CDP-RGVTASFAG---------CGSVPAGELCQ--CKDRVQGRICND----- 674
+C C+P G AG C G+ CQ C+ R G C+
Sbjct: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCR-HGASCDPRAGEC 204
Query: 675 -CKPLYWNL--QEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLD 730
C P Y + +E P G +C L + G C+ +G+C C C Q C
Sbjct: 205 LCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPP 264
Query: 731 GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G + + +C C GG CD TGQCHC + G RC +
Sbjct: 265 GTFGQNCSQ-----DCPCHHGG----QCDHVTGQCHCTAGYMGDRCQE 303
Score = 64.5 bits (150), Expect = 7e-09
Identities = 45/163 (27%), Positives = 63/163 (38%), Gaps = 16/163 (9%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEG 1408
+C+ GQC C +G C C G +GF + C C + C G C C +G
Sbjct: 282 QCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACECEPGYKG 341
Query: 1409 ENC-DRCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHC 1465
C +R P + GC C C+ N + C +G C C+ G C + C
Sbjct: 342 PRCQERLCPEGLHGP---GCTLPCPCD----ADNTISCHPVTGACTCQPGWSGHHCNESC 394
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+Y CTC ++G C T C C G+ C
Sbjct: 395 PVGYYGDGCQLPCTC-QNGAD---CHSITGGCTCAPGFMGEVC 433
Score = 50.8 bits (116), Expect = 9e-05
Identities = 42/148 (28%), Positives = 56/148 (37%), Gaps = 20/148 (13%)
Query: 1368 RTCSACRTGYYGFPN-CRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRG 1426
R S C GYY + C P C + +G C+ P + C C+P D G
Sbjct: 83 RRRSQCCPGYYENGDFCIPL-CTEECV---HGRCVSP-----DTC-HCEPGWGGPDCSSG 132
Query: 1427 CDDCN----CNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVPGHYAFPDCYQCTCN 1481
CD + C+ N C +G C C RG C+ C PG + C C
Sbjct: 133 CDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQC- 191
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
RHG + CD +C C G C+
Sbjct: 192 RHGAS---CDPRAGECLCAPGYTGVYCE 216
>AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA1781)
protein.
Length = 969
Score = 184 bits (447), Expect = 7e-45
Identities = 162/568 (28%), Positives = 228/568 (40%), Gaps = 88/568 (15%)
Query: 227 IGGRCMCN-GH-ADTCEPADPAGNLNILVC-RCQ-HNTCGPQCNKCCSGFE-QKKWRISQ 281
+ G+C C G+ D C+ P G+ RC HN G QC+ E + ++ +
Sbjct: 211 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHN--GGQCSPTTGACECEPGYKGPR 268
Query: 282 NWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
+R E + T C D + +S + G C CQ G +CN+
Sbjct: 269 CQERLCPEGLHGPGCTLPCPCDAD---NTISC-----HPVTGAC-TCQPGWSGHHCNESC 319
Query: 342 PTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFD 399
P Y YG D CQ PC C + +C +G C C P F C+ SCA G +
Sbjct: 320 PVGY--YG------DGCQLPCTCQ---NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG 368
Query: 400 YPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKNCECNTVG 457
PNC C+CN GT C+P DG C CK + G C + C G + C N C
Sbjct: 369 -PNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNC-NESCTCAN 422
Query: 458 SVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC 516
+ C + G C+C + G TC C G + + C+C + CD V+G C
Sbjct: 423 GAA--CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADG----CDPVTGHC 476
Query: 517 ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C AG+ G RCD C G + V C+C+ GS S DG C C F G
Sbjct: 477 CCLAGWTGIRCDSTCPPGRW-----GPNCSVSCSCENGGSCSPE---DGSCECAPGFRGP 528
Query: 576 QCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C + C PG+Y + C V S C +G+C C F GA C+ C ++
Sbjct: 529 LCQRICPPGFYGHGCAQPCPLCVHSS--RPCHHISGICECLPGFSGALCNQVCAGGYFGQ 586
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCE 691
+ C+C G + G CQC G+ C+ C P +W P
Sbjct: 587 DCAQLCSCANNGTCSPIDGS--------CQCFPGWIGKDCSQACPPGFW-----GPACFH 633
Query: 692 QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDI 750
C+C ++ +C+ + G C C C Q C F+ V C C
Sbjct: 634 ACSC------HNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV-----CQCQN 682
Query: 751 GGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G S CD +G+C C + G+ C+Q
Sbjct: 683 GAS----CDHISGKCTCRTGFTGQHCEQ 706
Score = 160 bits (389), Expect = 8e-38
Identities = 128/438 (29%), Positives = 173/438 (39%), Gaps = 65/438 (14%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHC 418
PC CD +T +C +G C C+P + C+ SC GY+ PCTC NG + C
Sbjct: 286 PCPCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ-NGAD---C 340
Query: 419 TPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
G C C + G+ C + C G Y P C + C CN G+ C + G CTCK +
Sbjct: 341 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT----CSPVDGSCTCKEGW 396
Query: 477 SGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGY 534
G C C +G + + C C C + G C C G+ G C+ C G
Sbjct: 397 QGLDCTLPCPSGTWGLNCNESCTCANGAA----CSPIDGSCSCTPGWLGDTCELPCPDGT 452
Query: 535 YMQVLGRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPDC-L 591
+ C + CDP G C CL + G +CD C PG + P+C +
Sbjct: 453 FGLNCSEHCDCSHADGCDPV---------TGHCCCLAGWTGIRCDSTCPPGRWG-PNCSV 502
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFA 650
SC+C+ GS ++G C C F G C C FY + + C P V +S
Sbjct: 503 SCSCENGGSCSP---EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPC---PLCVHSS-R 555
Query: 651 GCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGTLNSLGACN 708
C + +C+C G +CN C Y+ C Q C+C GT C+
Sbjct: 556 PCHHISG--ICECLPGFSGALCNQVCAGGYFGQD------CAQLCSCANNGT------CS 601
Query: 709 TKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G C C + C Q C GF+ C C G S C G CHC
Sbjct: 602 PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHA-----CSCHNGAS----CSAEDGACHC 652
Query: 768 HSRVEGRRCDQPIRAHYF 785
G C Q A +F
Sbjct: 653 TPGWTGLFCTQRCPAAFF 670
Score = 149 bits (362), Expect = 1e-34
Identities = 131/477 (27%), Positives = 181/477 (37%), Gaps = 74/477 (15%)
Query: 315 INGRYEGGGKCLNCQHNTEGINCNK-CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
++GR C +C+ G +C+ C ++ P+ CQC + C
Sbjct: 33 VHGRCVSPDTC-HCEPGWGGPDCSSGCDSDHWGPH--------CSNRCQCQ---NGALCN 80
Query: 374 EESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
+G C C F+ C CA G PC C G C P G C C Y
Sbjct: 81 PITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCR----HGASCDPRAGECLCAPGYT 136
Query: 433 GKSCE-ICEDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYY 489
G CE +C G + C+ C C G+ C +TG+C C ++G C Q C G +
Sbjct: 137 GVYCEELCPPGSHGAHCELRCPCQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTF 192
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVP- 547
+ C C G CD V+GQC C AG+ G RC ++C G + QC
Sbjct: 193 GQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFGSF------GFQCSQR 242
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDC-LSCNCDVSGSIGST 604
C+C G S + G C C + G +C + C G + P C L C CD +I S
Sbjct: 243 CDCHNGGQCSPT---TGACECEPGYKGPRCQERLCPEGLHG-PGCTLPCPCDADNTI-SC 297
Query: 605 CDDNGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQC 663
G C C+ + G C ++C +Y C C + A C S+ G C C
Sbjct: 298 HPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ------NGADCHSITGG--CTC 349
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
G +C + Y P C+CN GT C+ G C CK+
Sbjct: 350 APGFMGEVC----AVSCAAGTYGPNCSSICSCNNGGT------CSPVDGSCTCKEGWQGL 399
Query: 724 QCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C C G + L N+ C C G + C G C C G C+ P
Sbjct: 400 DCTLPCPSGTWGLNCNE-----SCTCANGAA----CSPIDGSCSCTPGWLGDTCELP 447
Score = 133 bits (321), Expect = 1e-29
Identities = 113/357 (31%), Positives = 136/357 (38%), Gaps = 48/357 (13%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C +RG CE+ CA G + G +PCQC H CD G CL CA G +CE
Sbjct: 86 CVCAAGFRGWRCEELCAPGTHG--KGCQLPCQCR-HGASCDPRAGECL-CAPGYTGVYCE 141
Query: 1795 -FCMSGYHGD--------ATVGTPRDCL-ICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
C G HG GT CACP + A C G S +C
Sbjct: 142 ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC- 200
Query: 1845 PGYGGARCEY------CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
P + G +C++ C AGY G + G + CS + + G C G C
Sbjct: 201 PCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSF--GFQCSQRCDCHNGGQCSPTTGAC 258
Query: 1899 LKCVNNTAGAACN--LCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVCRPGVIG 1955
+C G C LC G +G CT C CD C TG C C+PG G
Sbjct: 259 -ECEPGYKGPRCQERLCPEGLHGPG-----CTLPCPCDADNTISCHPVTGACTCQPGWSG 312
Query: 1956 EKCDRCAPDHWGLNTGLGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C+ P + G GC PC C C G C CA G G+ C CAAG
Sbjct: 313 HHCNESCPVGY---YGDGCQLPCTC---QNGADCHSITGGCTCAPGFMGEVCAVSCAAG- 365
Query: 2014 WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD-RCPE-RWVLIPQEGC 2068
Y + C+CN G G G C C G G C CP W L E C
Sbjct: 366 -TYGPNCSSICSCNNG---GTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC 418
Score = 132 bits (320), Expect = 2e-29
Identities = 110/333 (33%), Positives = 137/333 (41%), Gaps = 66/333 (19%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQCNGHSD-QCDVNTGICLNCADNTIGDH 1792
C+C Y+G C++ C EG + G +PC C+ + C TG C C G H
Sbjct: 258 CECEPGYKGPRCQERLCPEGLHG--PGCTLPCPCDADNTISCHPVTGAC-TCQPGWSGHH 314
Query: 1793 C-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C E C GY+GD C +P N A C G C C PG+ G
Sbjct: 315 CNESCPVGYYGDG------------CQLPCTCQNGA-DCHSITGG----CTCAPGFMGEV 357
Query: 1852 CEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C CAAG YG P NCS + + G+C ++G C C G C
Sbjct: 358 CAVSCAAGTYG--------------P-NCSSICSCNNGGTCSPVDGSCT-CKEGWQGLDC 401
Query: 1911 NL-CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
L C G +G NC +C C G A C G+C C PG +G+ C+ PD
Sbjct: 402 TLPCPSGTWG-----LNCNESCTCAN-GAA-CSPIDGSCSCTPGWLGDTCELPCPDG--- 451
Query: 1969 NTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCD-HCN 2025
GL C+ C+C S + CD G C C G TG +CD C G W C C+
Sbjct: 452 TFGLNCSEHCDC---SHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG---PNCSVSCS 505
Query: 2026 CNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
C G G G CEC PG G C R CP
Sbjct: 506 CENG---GSCSPEDGSCECAPGFRGPLCQRICP 535
Score = 131 bits (317), Expect = 4e-29
Identities = 109/371 (29%), Positives = 144/371 (38%), Gaps = 64/371 (17%)
Query: 227 IGGRCMCNGH--ADTCEPADPAGNLNILV---CRCQH-NTCGPQCNKCC-----SGFEQK 275
I G C C DTCE P G + C C H + C P CC +G
Sbjct: 429 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD 488
Query: 276 KWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGI 335
W C+C N + C+ PE G C C G
Sbjct: 489 STCPPGRWGPNCSVSCSCENGGS-CS--PE----------------DGSC-ECAPGFRGP 528
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CA 394
C + P + +G QPC H S+ C SG CEC P F C+ CA
Sbjct: 529 LCQRICPPGFYGHG-------CAQPCPLCVH-SSRPCHHISGICECLPGFSGALCNQVCA 580
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC-EICEDGYYSPECKN-CE 452
GYF + C+C NGT C+P DG C C + GK C + C G++ P C + C
Sbjct: 581 GGYFGQDCAQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACS 636
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDD 511
C+ S C G C C ++G C Q C A ++ + C C + CD
Sbjct: 637 CHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGAS----CDH 688
Query: 512 VSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLT 570
+SG+C C+ GF G C+Q C G + G ++ C N ST G C C
Sbjct: 689 ISGKCTCRTGFTGQHCEQRCAPGTFGY--GCQQLCECMN------NSTCDHVTGTCYCSP 740
Query: 571 NFGGAQCDQCS 581
F G +CDQ +
Sbjct: 741 GFKGIRCDQAA 751
Score = 126 bits (304), Expect = 2e-27
Identities = 104/328 (31%), Positives = 140/328 (42%), Gaps = 62/328 (18%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHC 1793
C C + G+ C+ C G R V C C NG S C G C CA G C
Sbjct: 476 CCCLAGWTGIRCDSTCPPG--RWGPNCSVSCSCENGGS--CSPEDGSC-ECAPGFRGPLC 530
Query: 1794 E-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G++G G + C +C P ++ + C+ C PG+ GA C
Sbjct: 531 QRICPPGFYGH---GCAQPCPLCV-HSSRPCHHISGICE-----------CLPGFSGALC 575
Query: 1853 -EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
+ CA GY+G D + C+C+ N G+C I+G C +C G C+
Sbjct: 576 NQVCAGGYFG---------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDCS 619
Query: 1912 -LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLN 1969
C PGF+G A F AC C A C + G C C PG G C RC +G +
Sbjct: 620 QACPPGFWGPACFH----ACSCHNG--ASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD 673
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDH-CNCN 2027
G C C G + CD +G+C C G TG+ C+Q CA G + Y GC C C
Sbjct: 674 CGRVCQ-CQNGAS-----CDHISGKCTCRTGFTGQHCEQRCAPGTFGY---GCQQLCECM 724
Query: 2028 TGYSVGFMCNATGQCECLPGVIGEKCDR 2055
+ + TG C C PG G +CD+
Sbjct: 725 NNSTCD---HVTGTCYCSPGFKGIRCDQ 749
Score = 121 bits (291), Expect = 6e-26
Identities = 104/352 (29%), Positives = 134/352 (38%), Gaps = 57/352 (16%)
Query: 1735 ECQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQ----CNGHSDQCDVNTG----ICLN-C 1784
EC C Y G+ CE+ C G + PCQ C+ + +C G +C C
Sbjct: 128 ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPC 187
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICA------CPMPYPSNNFALSCDL---SEN 1835
T G +C +HG C A C P +F C N
Sbjct: 188 PPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHN 247
Query: 1836 GSLIS-----CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS 1890
G S C C+PGY G RC+ PE LH PC C + + S
Sbjct: 248 GGQCSPTTGACECEPGYKGPRCQERLC-----PE--GLHGPGCTLPCPCDAD----NTIS 296
Query: 1891 CDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C + G C C +G CN C G+YGD C C ADC S TG C C
Sbjct: 297 CHPVTGAC-TCQPGWSGHHCNESCPVGYYGDGC----QLPCTCQ--NGADCHSITGGCTC 349
Query: 1950 RPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD- 2007
PG +GE C CA +G N C+ CN G C +G C C +G G C
Sbjct: 350 APGFMGEVCAVSCAAGTYGPNCSSICS-CNNG-----GTCSPVDGSCTCKEGWQGLDCTL 403
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD-RCPE 2058
C +G W + + C C G + G C C PG +G+ C+ CP+
Sbjct: 404 PCPSGTWGLNCN--ESCTCANGAACS---PIDGSCSCTPGWLGDTCELPCPD 450
Score = 102 bits (244), Expect = 3e-20
Identities = 77/224 (34%), Positives = 102/224 (45%), Gaps = 40/224 (17%)
Query: 1840 SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP-CNCSGNINPQDPGSCDSINGDC 1898
+C+C+PG+GG C ++G D+D H G +C C C Q+ C+ I G C
Sbjct: 42 TCHCEPGWGGPDC---SSGC-----DSD-HWGPHCSNRCQC------QNGALCNPITGAC 86
Query: 1899 LKCVNNTAGAACN-LCAPGFYGDAIFSKNC-TACICDEFGMADCDSTTGTCVCRPGVIGE 1956
+ C G C LCAPG +G K C C C G A CD G C+C PG G
Sbjct: 87 V-CAAGFRGWRCEELCAPGTHG-----KGCQLPCQC-RHG-ASCDPRAGECLCAPGYTGV 138
Query: 1957 KCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFW 2014
C+ C P G + L C PC G C G+C C G TG C Q C G
Sbjct: 139 YCEELCPPGSHGAHCELRC-PCQNG-----GTCHHITGECACPPGWTGAVCAQPCPPG-- 190
Query: 2015 NYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC-DRCP 2057
+ ++ C C+ G G + TGQC C G +G++C + CP
Sbjct: 191 TFGQNCSQDCPCHHG---GQCDHVTGQCHCTAGYMGDRCQEECP 231
Score = 101 bits (241), Expect = 6e-20
Identities = 85/324 (26%), Positives = 127/324 (39%), Gaps = 50/324 (15%)
Query: 470 CTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C C+ + G C+ C + ++ C C ++C+ ++G C+C AGF G RC+
Sbjct: 43 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNG----ALCNPITGACVCAAGFRGWRCE 98
Query: 529 Q-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYK 586
+ C G + G+ Q +PC C S G+C C + G C++ C PG +
Sbjct: 99 ELCAPGTH----GKGCQ-LPCQCRHGASCDPRA---GECLCAPGYTGVYCEELCPPGSHG 150
Query: 587 YPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRG 644
L C C G TC G C C + GA C C + ++C C G
Sbjct: 151 AHCELRCPCQNGG----TCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 206
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
C V G+ C C G C QE PFG C+ ++
Sbjct: 207 Q------CDHV-TGQ-CHCTAGYMGDRC----------QEECPFGSFGFQCSQRCDCHNG 248
Query: 705 GACNTKSGQCVCKQHVGERQCDQ--CLDGFYRLQTNDVFGCT-ECDCDIGGSIDNNCDKT 761
G C+ +G C C+ +C + C +G + GCT C CD +I +C
Sbjct: 249 GQCSPTTGACECEPGYKGPRCQERLCPEGLHGP------GCTLPCPCDADNTI--SCHPV 300
Query: 762 TGQCHCHSRVEGRRCDQPIRAHYF 785
TG C C G C++ Y+
Sbjct: 301 TGACTCQPGWSGHHCNESCPVGYY 324
Score = 99.1 bits (236), Expect = 3e-19
Identities = 88/281 (31%), Positives = 117/281 (41%), Gaps = 54/281 (19%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQ-CDVNTGICLNCADNTIGDHC 1793
C+C +RG C++ C G Y G PC HS + C +GIC C G C
Sbjct: 519 CECAPGFRGPLCQRICPPGFYG--HGCAQPCPLCVHSSRPCHHISGIC-ECLPGFSGALC 575
Query: 1794 -EFCMSGYHGDATVGTPRDCL-ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
+ C GY G +DC +C+C +NN +C + SC C PG+ G
Sbjct: 576 NQVCAGGYFG-------QDCAQLCSC-----ANNG--TCSPIDG----SCQCFPGWIGKD 617
Query: 1852 C-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C + C G++G H C+C SC + +G C C G C
Sbjct: 618 CSQACPPGFWG---PACFHA------CSCHNG------ASCSAEDGAC-HCTPGWTGLFC 661
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCD-RCAPDHWGLN 1969
P A F K+C +C A CD +G C CR G G+ C+ RCAP +G
Sbjct: 662 TQRCPA----AFFGKDCGR-VCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY- 715
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
GC C + ST CD G C C+ G G +CDQ A
Sbjct: 716 ---GCQQL-CECMNNST-CDHVTGTCYCSPGFKGIRCDQAA 751
Score = 91.5 bits (217), Expect = 5e-17
Identities = 62/179 (34%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAIC 1394
A+ C C G+ C+ G C C P IG+ CS AC G++G P C C C + A C
Sbjct: 589 AQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWG-PACFHACSCHNGASC 643
Query: 1395 D-DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
++G C C G C RC F D R C C N C+ SGKC
Sbjct: 644 SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQ------NGASCDHISGKCT 694
Query: 1453 CRENVRGRVCDH-CVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
CR G+ C+ C PG + + C Q C C + T CD T CYC +G CD
Sbjct: 695 CRTGFTGQHCEQRCAPGTFGY-GCQQLCECMNNST----CDHVTGTCYCSPGFKGIRCD 748
Score = 78.6 bits (185), Expect = 4e-13
Identities = 55/185 (29%), Positives = 71/185 (38%), Gaps = 23/185 (12%)
Query: 1333 YNSGAR-PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCP 1389
Y G + PC C +C++ G C C P +G C+ +C G YG PNC C C
Sbjct: 324 YGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCN 378
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADS 1448
+ C +G C C + +G +C P G NCN N C
Sbjct: 379 NGGTCSPVDGSCTCKEGWQGLDCTLPCP--------SGTWGLNCNESCTCANGAACSPID 430
Query: 1449 GKCACRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
G C+C G C+ C G + C C+ H D CD T C C G
Sbjct: 431 GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS-HA---DGCDPVTGHCCCLAGWTGIR 486
Query: 1508 CD-TC 1511
CD TC
Sbjct: 487 CDSTC 491
Score = 73.7 bits (173), Expect = 1e-11
Identities = 56/195 (28%), Positives = 71/195 (36%), Gaps = 22/195 (11%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD- 1396
PC CD + C+ G C C+P G C+ +C GYYG PC C + A C
Sbjct: 286 PCPCD--ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI 343
Query: 1397 NGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACR 1454
G C C GE C C T+ C C+CN G C G C C+
Sbjct: 344 TGGCTCAPGFMGEVCAVSCAAGTYG----PNCSSICSCNNGGT------CSPVDGSCTCK 393
Query: 1455 ENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCK 1512
E +G C C G + CTC +G C C C G C+ C
Sbjct: 394 EGWQGLDCTLPCPSGTWGLNCNESCTC-ANGA---ACSPIDGSCSCTPGWLGDTCELPCP 449
Query: 1513 EEYFNLQDDNPDGCT 1527
+ F L C+
Sbjct: 450 DGTFGLNCSEHCDCS 464
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/183 (28%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1333 YNSG-ARPC-LCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCP 1389
Y G A+PC LC + C+ G C C P G C+ C GY+G + C C
Sbjct: 539 YGHGCAQPCPLCVH---SSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCA 595
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEAD 1447
+ C +G C C G++C + P F C C+C+ N C A+
Sbjct: 596 NNGTCSPIDGSCQCFPGWIGKDCSQACPPGF---WGPACFHACSCH------NGASCSAE 646
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQ 1506
G C C G C P + DC + C C ++G + CD + +C C+T GQ
Sbjct: 647 DGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQC-QNGAS---CDHISGKCTCRTGFTGQ 702
Query: 1507 ACD 1509
C+
Sbjct: 703 HCE 705
Score = 71.7 bits (168), Expect = 5e-11
Identities = 51/167 (30%), Positives = 62/167 (37%), Gaps = 20/167 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEGE 1409
CN G C C G C C G +G PC C A CD G C+C G
Sbjct: 79 CNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGV 138
Query: 1410 NCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVP 1467
C+ C P + + C C G C +G+CAC G VC C P
Sbjct: 139 YCEELCPPGSHGAHCELRCP---CQNGGT------CHHITGECACPPGWTGAVCAQPCPP 189
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
G + C C+ G CD T QC+C G D C+EE
Sbjct: 190 GTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMG---DRCQEE 229
Score = 70.1 bits (164), Expect = 1e-10
Identities = 45/156 (28%), Positives = 65/156 (41%), Gaps = 21/156 (13%)
Query: 1359 CPCKPNVIGRTCSA-CRTGYYGFPNC-RPCHCPSTAICDD-NGMCICPKNVEGENCDR-C 1414
C C+P G CS+ C + ++G P+C C C + A+C+ G C+C G C+ C
Sbjct: 43 CHCEPGWGGPDCSSGCDSDHWG-PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELC 101
Query: 1415 KPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVPGHYAF 1472
P T +GC C C + C+ +G+C C G C+ C PG +
Sbjct: 102 APGTHG----KGCQLPCQCR------HGASCDPRAGECLCAPGYTGVYCEELCPPGSHGA 151
Query: 1473 PDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C C GT C T +C C G C
Sbjct: 152 HCELRCPCQNGGT----CHHITGECACPPGWTGAVC 183
Score = 67.3 bits (157), Expect = 1e-09
Identities = 48/171 (28%), Positives = 58/171 (33%), Gaps = 18/171 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G C C P +G TC C G +G C C CD G C C G
Sbjct: 426 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 485
Query: 1410 NCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CV 1466
CD C P + C C+C G C + G C C RG +C C
Sbjct: 486 RCDSTCPPGRWG----PNCSVSCSCENGG------SCSPEDGSCECAPGFRGPLCQRICP 535
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYF 1516
PG Y C H + C + C C G C+ C YF
Sbjct: 536 PGFYGHGCAQPCPLCVHSSR--PCHHISGICECLPGFSGALCNQVCAGGYF 584
Score = 64.5 bits (150), Expect = 7e-09
Identities = 45/163 (27%), Positives = 63/163 (38%), Gaps = 16/163 (9%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEG 1408
+C+ GQC C +G C C G +GF + C C + C G C C +G
Sbjct: 207 QCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACECEPGYKG 266
Query: 1409 ENC-DRCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHC 1465
C +R P + GC C C+ N + C +G C C+ G C + C
Sbjct: 267 PRCQERLCPEGLHGP---GCTLPCPCD----ADNTISCHPVTGACTCQPGWSGHHCNESC 319
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+Y CTC ++G C T C C G+ C
Sbjct: 320 PVGYYGDGCQLPCTC-QNGAD---CHSITGGCTCAPGFMGEVC 358
Score = 54.8 bits (126), Expect = 6e-06
Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 12/126 (9%)
Query: 1389 PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCN----CNPLGVVGNQLQC 1444
P TA+C + C+ + V + C C+P D GCD + C+ N C
Sbjct: 23 PGTALCTEE--CVHGRCVSPDTC-HCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALC 79
Query: 1445 EADSGKCACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+G C C RG C+ C PG + C C RHG + CD +C C
Sbjct: 80 NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQC-RHGAS---CDPRAGECLCAPGY 135
Query: 1504 RGQACD 1509
G C+
Sbjct: 136 TGVYCE 141
>X76939-1|CAA54258.1| 1581|Homo sapiens laminin A3 protein.
Length = 1581
Score = 181 bits (440), Expect = 5e-44
Identities = 186/774 (24%), Positives = 322/774 (41%), Gaps = 72/774 (9%)
Query: 2387 LTSEATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXX 2446
L EA HA L++ A+ L + N Q ++
Sbjct: 344 LVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 403
Query: 2447 XXXXNVTKLNRILDERVRPARERSSSLLADA----TKAQHAVDQKLLPNLTATEEVLRKI 2502
+ +D ++ ++ S +LL A KA+ + D+ + L +
Sbjct: 404 NTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARK 463
Query: 2503 RDHLSRADDDDNAIQXXXXXXXXXXXXXXXNKADRVNATIGTTFSVMSHLGPELATSKDW 2562
+R D +Q + N T T V P +W
Sbjct: 464 SALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRT---TMEVQQATAPMANNLTNW 520
Query: 2563 AQTLPKLADEGQKMTSN-VESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQK 2621
+Q L N ++N+ ++ PQ+ TV+ +Q+
Sbjct: 521 SQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSAS-----IQR 575
Query: 2622 LKDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR--------TKE 2673
+++L+ Q R+VA++IQV + FD S ++ ++D++ T +S Y + T+
Sbjct: 576 IRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTET 635
Query: 2674 KDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVA 2733
D FILYLG+ + +YM + I+N V ++G + +D
Sbjct: 636 ADQFILYLGS-------KNAKKEYMGLAIKNDNLVYVYNLGTKD------VEIPLDSKPV 682
Query: 2734 DN--RWYQVI-VDRLGRRVKLSIR-ESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
+ ++ ++ ++R+G+ K+ + SL + + K+ + G ++ +LD E + YV
Sbjct: 683 SSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYV 742
Query: 2790 GGVPSDAKL-QGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQ----RDKLISSQ 2844
GGVPS+ KL ++ P F G +E + + + L+NF + + RDKL +Q
Sbjct: 743 GGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQ 802
Query: 2845 SGPQEYRFDGRGYATMAG--RGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQD 2902
S Y FDG GYA + R Q + + RT A NGLI L+ G FF L M++
Sbjct: 803 SRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRN 862
Query: 2903 GRVYLQVSLGNTEDLIIVGTT---RAYNDGKWHKLD-ARRFLAKCSLTVDNEVLKAESNS 2958
G +++ G + + + T ND K+H++ K L VD +K+ N
Sbjct: 863 GYLHVFYDFGFSSGRVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNE 922
Query: 2959 PSADIPSLDTMNFGGNNKGILQ-------VP-DRGFDGCMRQISINGVNLDLSENLESIG 3010
IP D + GG ILQ +P D F GCM+ + +L E E++G
Sbjct: 923 -KMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLG 980
Query: 3011 MAYGCQFASLVS----FNGTDSYLRFVDVTS--ENPQLTLKFKTAKPNGLLFVYVSRTQT 3064
+ YGC SL+S FNG S++ + S + + F+T +PNGLLF Y S +
Sbjct: 981 VGYGCPEDSLISRRAYFNG-QSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGS-- 1037
Query: 3065 AIMPDSISLSLVNGKLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVD 3118
D S+SL NG +++ + ++ + YND H + + + + +L+VD
Sbjct: 1038 ----DVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1087
Score = 146 bits (353), Expect = 2e-33
Identities = 105/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 1228 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 1283
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S YND WH V R G+L +D V E S+
Sbjct: 1284 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1343
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 1344 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 1402
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 1403 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1458
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 1459 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 1515
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 1516 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1574
Query: 3662 VGVCP 3666
+ CP
Sbjct: 1575 INSCP 1579
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + YND
Sbjct: 1251 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYND 1308
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 1309 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 1368
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 1369 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 1424
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 1425 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 1482
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 1483 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 1540
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 1541 LAPSKPFTGCIRHFVIDG 1558
Score = 55.2 bits (127), Expect = 4e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 3041 QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV---VSQREQLDTGLNTYN 3097
Q +++ +T +G++F YVS + D ++L L +G+LV V ++ YN
Sbjct: 1252 QFSIRLRTRSSHGMIF-YVSDQEEN---DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYN 1307
Query: 3098 DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAP-PPLHILDGVLFIGGVQPGYVVSG-SLG 3155
D WH + S+ +LV+D P + G +++GGV PG V +
Sbjct: 1308 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQIN 1367
Query: 3156 SKVPFTGCIGDATING-QVLNLLEPFSNNSVTFG--RCGTTITTGG 3198
S F+GC+ + +NG + + + FS G GT +T G
Sbjct: 1368 SIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEG 1413
Score = 46.0 bits (104), Expect = 0.003
Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 1246 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 1297
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + D W+ VI R +L I D + E LP
Sbjct: 1298 ------LKIRSQEKYNDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 1343
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 1344 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 1389
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 1390 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 1446
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 1447 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 1506
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 1507 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1565
>U86759-1|AAC51247.1| 580|Homo sapiens netrin-2 like protein
protein.
Length = 580
Score = 177 bits (431), Expect = 6e-43
Identities = 112/369 (30%), Positives = 175/369 (47%), Gaps = 32/369 (8%)
Query: 37 CDANNEAKKHPPEYAVDDRRT----WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA++ + H P T W+S L R V LT+ LG+ F + +V ++
Sbjct: 67 CDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPL--NVTLTVPLGKAFELVFVSLRF 124
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVICSTE 149
++P P L KS D+G+++ P +FS C+ +G+ + P +C
Sbjct: 125 CSAP-PASVALLKSQDHGRSWAPLGFFSSH---CDLDYGRLPAPANGPAGPGPEALCFPA 180
Query: 150 YSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVAR 209
P G + S+ + P +S VLQ+W AT+VR+ L R +
Sbjct: 181 -PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPST------AGDP 233
Query: 210 QDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCC 269
+D Y Y+ D+ +GGRC CNGHA C D G+L +C C+H T GP C +C
Sbjct: 234 RDMEAVVPYSYAATDLQVGGRCKCNGHASRCL-LDTQGHL---ICDCRHGTEGPDCGRCK 289
Query: 270 SGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQ 329
+ + W+ + + +C C+C+ H C ++ E+ RLS GR GG CLNC+
Sbjct: 290 PFYCDRPWQRATARESHACLACSCNGHARRCRFNMEL--YRLS----GR-RSGGVCLNCR 342
Query: 330 HNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPP 388
HNT G +C+ CR +YR G+ + C+ C C P + G C + +G+C C+
Sbjct: 343 HNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGL 402
Query: 389 DCSSCAYGY 397
C+ CA G+
Sbjct: 403 TCNRCAPGF 411
Score = 82.2 bits (194), Expect = 3e-14
Identities = 49/171 (28%), Positives = 74/171 (43%), Gaps = 29/171 (16%)
Query: 347 PYGKRWDELDVCQPCQCDPHFSTGNCEEESGR-CECRPEFQPPDCSSCAYGYFDYP---- 401
PY +L V C+C+ H S + + C+CR + PDC C Y D P
Sbjct: 241 PYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRA 300
Query: 402 ------NCKPCTCNLNGTEGEHCTP--------TDGLC-PCKYNYAGKSCEICEDGYYSP 446
C C+CN + + G+C C++N AG+ C C +G+Y
Sbjct: 301 TARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRD 360
Query: 447 E---------CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C+ C+C+ VG+ C++ TG C CK +G TCN+C G+
Sbjct: 361 PGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 70.5 bits (165), Expect = 1e-10
Identities = 49/161 (30%), Positives = 64/161 (39%), Gaps = 12/161 (7%)
Query: 1765 CQCNGHSDQC--DVNTGICLNCADNTIGDHCEFCMSGYHGD----ATVGTPRDCLICACP 1818
C+CNGH+ +C D + +C T G C C Y AT CL C+C
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 1819 MPYPSNNFALSC-DLSENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
F + LS S C NC+ G C YC G+Y P L C+
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDP-GRALSDRRACRA 373
Query: 1877 CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
C+C + +C+ G C C + G CN CAPGF
Sbjct: 374 CDCH-PVGAAGK-TCNQTTGQC-PCKDGVTGLTCNRCAPGF 411
Score = 70.5 bits (165), Expect = 1e-10
Identities = 43/145 (29%), Positives = 58/145 (40%), Gaps = 28/145 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G C +C + P S C+ C CNGH+ +C N
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
G+CLNC NT G HC +C G++ D + R C C C +P +C
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDC---HPVGAAGKTC---- 386
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGY 1859
N + C C+ G G C CA G+
Sbjct: 387 NQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/183 (27%), Positives = 68/183 (37%), Gaps = 36/183 (19%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H + C D + G +C+H TEG +C +C+P Y RP+
Sbjct: 255 CKCNGHASRCLLDTQ----------------GHLICDCRHGTEGPDCGRCKPFYCDRPWQ 298
Query: 350 KRWD-ELDVCQPCQCDPHFSTGNCEEE----SGR-----C-ECRPEFQPPDCSSCAYGYF 398
+ E C C C+ H E SGR C CR C C G++
Sbjct: 299 RATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358
Query: 399 DYPN--------CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN 450
P C+ C C+ G G+ C T G CPCK G +C C G+
Sbjct: 359 RDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPV 418
Query: 451 CEC 453
C
Sbjct: 419 APC 421
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/153 (31%), Positives = 60/153 (39%), Gaps = 27/153 (17%)
Query: 1386 CHC---PSTAICDDNG--MCICPKNVEGENCDRCKPYTFNFDVQRG-------CDDCNCN 1433
C C S + D G +C C EG +C RCKP+ + QR C C+CN
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 1434 P------LGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQC 1478
+ +L G C CR N GR C +C G Y P C C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 1479 TCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTC 1511
C+ G C+Q T QC CK V G C+ C
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRC 407
Score = 68.1 bits (159), Expect = 6e-10
Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 660 LCQCKDRVQGRICNDCKPLY----WN-LQEYNPFGCEQCNCN-----LAGTLNSLGACNT 709
+C C+ +G C CKP Y W C C+CN +
Sbjct: 273 ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332
Query: 710 KSGQ-CV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
+SG C+ C+ + R C C +GFYR +D C CDC G+ C++TTGQ
Sbjct: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392
Query: 765 CHCHSRVEGRRCDQ 778
C C V G C++
Sbjct: 393 CPCKDGVTGLTCNR 406
Score = 60.9 bits (141), Expect = 8e-08
Identities = 43/157 (27%), Positives = 60/157 (38%), Gaps = 26/157 (16%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGY----YMQVLGRERQ-CVPCNCD 551
C +G D G C C+ G GP C +C Y + + RE C+ C+C+
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 552 PTGSTS---------TSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPD--------CLSC 593
+ + G C NC N G C C G+Y+ P C +C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 594 NCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQF 629
+C G+ G TC+ G C CK G C+ C F
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 60.5 bits (140), Expect = 1e-07
Identities = 42/157 (26%), Positives = 61/157 (38%), Gaps = 30/157 (19%)
Query: 408 CNLNGTEGEHCTPTDG--LCPCKYNYAGKSCEICEDGYY-----------SPECKNCECN 454
C NG T G +C C++ G C C+ Y S C C CN
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 455 TVGS---VSYVCDKLTGD-----C-TCKSKYSGRTCNQCQAGYYNYP--------TCKPC 497
+ +L+G C C+ +GR C+ C+ G+Y P C+ C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 498 NCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY 534
+C G C+ +GQC CK G G C++C G+
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 59.7 bits (138), Expect = 2e-07
Identities = 38/157 (24%), Positives = 62/157 (39%), Gaps = 23/157 (14%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCD 500
C+CN S + + C C+ G C +C+ Y + P C C+C+
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 501 TSGTEPSICDDV--------SGQCI-CKAGFGGPRCDQCLSGYYM---QVLGRERQCVPC 548
++ G C+ C+ G C C G+Y + L R C C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 549 NCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGY 584
+C P G+ +C+ G+C C G C++C+PG+
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 57.6 bits (133), Expect = 8e-07
Identities = 51/172 (29%), Positives = 67/172 (38%), Gaps = 31/172 (18%)
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGD----- 1920
TDL G CK C+G+ + D+ C + T G C C P FY D
Sbjct: 247 TDLQVGGRCK---CNGHASRC---LLDTQGHLICDCRHGTEGPDCGRCKP-FYCDRPWQR 299
Query: 1921 --AIFSKNCTACICD------EFGMA----DCDSTTGTCV-CRPGVIGEKCDRCAPDHW- 1966
A S C AC C+ F M + G C+ CR G C C +
Sbjct: 300 ATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR 359
Query: 1967 ----GLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
L+ C C+C + + C+ GQC C GVTG C++CA GF
Sbjct: 360 DPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 56.8 bits (131), Expect = 1e-06
Identities = 45/157 (28%), Positives = 60/157 (38%), Gaps = 26/157 (16%)
Query: 1334 NSGARPCLCDFMGSTELECN--TFGGQCP-CKPNVIGRTCSACRTGYYGFPNCRPCHCPS 1390
N A CL D G +C T G C CKP R R C C C
Sbjct: 258 NGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQ--RATARESHACLACSCNG 315
Query: 1391 TAI-CDDN------------GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCN 1431
A C N G+C+ C N G +C C+ + +R C C+
Sbjct: 316 HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375
Query: 1432 CNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C+P+G G C +G+C C++ V G C+ C PG
Sbjct: 376 CHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAPG 410
Score = 56.4 bits (130), Expect = 2e-06
Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 24/134 (17%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGL---GCTPCNCGIASESTQCDDD-------- 1991
C CR G G C RC P + W T C C+C + + + +
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWN------YTKDGCDHCNCNTGYSVGFMCN-ATGQC 2042
G C C G+ C C GF+ + C C+C+ + G CN TGQC
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393
Query: 2043 ECLPGVIGEKCDRC 2056
C GV G C+RC
Sbjct: 394 PCKDGVTGLTCNRC 407
Score = 52.8 bits (121), Expect = 2e-05
Identities = 56/237 (23%), Positives = 86/237 (36%), Gaps = 37/237 (15%)
Query: 593 CNCDVSGSIGSTCDDNG--LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNC 640
C C+ S D G +C C+ +G C C+ + + P AC C+C
Sbjct: 255 CKCNGHAS-RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSC 313
Query: 641 DPRGVTASFAG-----CGSVPAGELCQCKDRVQGRICNDCKPLYWN---LQEYNPFGCEQ 692
+ F G G C+ GR C+ C+ ++ + C
Sbjct: 314 NGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRA 373
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
C+C+ G CN +GQC CK V C++C GF + + V C + I G
Sbjct: 374 CDCHPVGAAGK--TCNQTTGQCPCKDGVTGLTCNRCAPGFQQ-SRSPVAPCVK--TPIPG 428
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQF---QYEVEDGVTQSGPVR 806
+++ C H C +P R Y +L +F Y V+ V G R
Sbjct: 429 PTEDSSPVQPQDCDSH-------C-KPARGSYRISLKKFCKKDYAVQVAVGARGEAR 477
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/114 (29%), Positives = 45/114 (39%), Gaps = 8/114 (7%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPC-LCDF--MGSTELECNTFGGQCPCKP 1363
C + + + CRE + S R C CD +G+ CN GQCPCK
Sbjct: 338 CLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKD 397
Query: 1364 NVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RCKP 1416
V G TC+ C G+ C T I G V+ ++CD CKP
Sbjct: 398 GVTGLTCNRCAPGFQQ-SRSPVAPCVKTPI---PGPTEDSSPVQPQDCDSHCKP 447
Score = 34.7 bits (76), Expect = 6.4
Identities = 23/81 (28%), Positives = 28/81 (34%), Gaps = 8/81 (9%)
Query: 1466 VPGHYAFPDCY---QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFN----- 1517
VP YA D +C CN H + + Q C C+ G C CK Y +
Sbjct: 240 VPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQR 299
Query: 1518 LQDDNPDGCTKCFCFGKTTRC 1538
C C C G RC
Sbjct: 300 ATARESHACLACSCNGHARRC 320
>U86758-1|AAC51246.1| 580|Homo sapiens netrin-2 like protein
protein.
Length = 580
Score = 177 bits (431), Expect = 6e-43
Identities = 112/369 (30%), Positives = 175/369 (47%), Gaps = 32/369 (8%)
Query: 37 CDANNEAKKHPPEYAVDDRRT----WWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA++ + H P T W+S L R V LT+ LG+ F + +V ++
Sbjct: 67 CDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPL--NVTLTVPLGKAFELVFVSLRF 124
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGK---ESLQPITKDDSVICSTE 149
++P P L KS D+G+++ P +FS C+ +G+ + P +C
Sbjct: 125 CSAP-PASVALLKSQDHGRSWAPLGFFSSH---CDLDYGRLPAPANGPAGPGPEALCFPA 180
Query: 150 YSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEWTRATNVRLRLLRTKNLLGHLMSVAR 209
P G + S+ + P +S VLQ+W AT+VR+ L R +
Sbjct: 181 -PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPST------AGDP 233
Query: 210 QDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCC 269
+D Y Y+ D+ +GGRC CNGHA C D G+L +C C+H T GP C +C
Sbjct: 234 RDMEAVVPYSYAATDLQVGGRCKCNGHASRCL-LDTQGHL---ICDCRHGTEGPDCGRCK 289
Query: 270 SGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQ 329
+ + W+ + + +C C+C+ H C ++ E+ RLS GR GG CLNC+
Sbjct: 290 PFYCDRPWQRATARESHACLACSCNGHARRCRFNMEL--YRLS----GR-RSGGVCLNCR 342
Query: 330 HNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPP 388
HNT G +C+ CR +YR G+ + C+ C C P + G C + +G+C C+
Sbjct: 343 HNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGL 402
Query: 389 DCSSCAYGY 397
C+ CA G+
Sbjct: 403 TCNRCAPGF 411
Score = 82.2 bits (194), Expect = 3e-14
Identities = 49/171 (28%), Positives = 74/171 (43%), Gaps = 29/171 (16%)
Query: 347 PYGKRWDELDVCQPCQCDPHFSTGNCEEESGR-CECRPEFQPPDCSSCAYGYFDYP---- 401
PY +L V C+C+ H S + + C+CR + PDC C Y D P
Sbjct: 241 PYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRA 300
Query: 402 ------NCKPCTCNLNGTEGEHCTP--------TDGLC-PCKYNYAGKSCEICEDGYYSP 446
C C+CN + + G+C C++N AG+ C C +G+Y
Sbjct: 301 TARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRD 360
Query: 447 E---------CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C+ C+C+ VG+ C++ TG C CK +G TCN+C G+
Sbjct: 361 PGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 70.5 bits (165), Expect = 1e-10
Identities = 49/161 (30%), Positives = 64/161 (39%), Gaps = 12/161 (7%)
Query: 1765 CQCNGHSDQC--DVNTGICLNCADNTIGDHCEFCMSGYHGD----ATVGTPRDCLICACP 1818
C+CNGH+ +C D + +C T G C C Y AT CL C+C
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 1819 MPYPSNNFALSC-DLSENGSLISC-NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
F + LS S C NC+ G C YC G+Y P L C+
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDP-GRALSDRRACRA 373
Query: 1877 CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
C+C + +C+ G C C + G CN CAPGF
Sbjct: 374 CDCH-PVGAAGK-TCNQTTGQC-PCKDGVTGLTCNRCAPGF 411
Score = 70.5 bits (165), Expect = 1e-10
Identities = 43/145 (29%), Positives = 58/145 (40%), Gaps = 28/145 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G C +C + P S C+ C CNGH+ +C N
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
G+CLNC NT G HC +C G++ D + R C C C +P +C
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDC---HPVGAAGKTC---- 386
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGY 1859
N + C C+ G G C CA G+
Sbjct: 387 NQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 70.1 bits (164), Expect = 1e-10
Identities = 50/183 (27%), Positives = 68/183 (37%), Gaps = 36/183 (19%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H + C D + G +C+H TEG +C +C+P Y RP+
Sbjct: 255 CKCNGHASRCLLDTQ----------------GHLICDCRHGTEGPDCGRCKPFYCDRPWQ 298
Query: 350 KRWD-ELDVCQPCQCDPHFSTGNCEEE----SGR-----C-ECRPEFQPPDCSSCAYGYF 398
+ E C C C+ H E SGR C CR C C G++
Sbjct: 299 RATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358
Query: 399 DYPN--------CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN 450
P C+ C C+ G G+ C T G CPCK G +C C G+
Sbjct: 359 RDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPV 418
Query: 451 CEC 453
C
Sbjct: 419 APC 421
Score = 69.3 bits (162), Expect = 2e-10
Identities = 48/153 (31%), Positives = 60/153 (39%), Gaps = 27/153 (17%)
Query: 1386 CHC---PSTAICDDNG--MCICPKNVEGENCDRCKPYTFNFDVQRG-------CDDCNCN 1433
C C S + D G +C C EG +C RCKP+ + QR C C+CN
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 1434 P------LGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQC 1478
+ +L G C CR N GR C +C G Y P C C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 1479 TCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTC 1511
C+ G C+Q T QC CK V G C+ C
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRC 407
Score = 68.1 bits (159), Expect = 6e-10
Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 660 LCQCKDRVQGRICNDCKPLY----WN-LQEYNPFGCEQCNCN-----LAGTLNSLGACNT 709
+C C+ +G C CKP Y W C C+CN +
Sbjct: 273 ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332
Query: 710 KSGQ-CV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
+SG C+ C+ + R C C +GFYR +D C CDC G+ C++TTGQ
Sbjct: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392
Query: 765 CHCHSRVEGRRCDQ 778
C C V G C++
Sbjct: 393 CPCKDGVTGLTCNR 406
Score = 60.9 bits (141), Expect = 8e-08
Identities = 43/157 (27%), Positives = 60/157 (38%), Gaps = 26/157 (16%)
Query: 499 CDTSGTEPSICDDVSGQ--CICKAGFGGPRCDQCLSGY----YMQVLGRERQ-CVPCNCD 551
C +G D G C C+ G GP C +C Y + + RE C+ C+C+
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 552 PTGSTS---------TSCSADGKC-NCLTNFGGAQCDQCSPGYYKYPD--------CLSC 593
+ + G C NC N G C C G+Y+ P C +C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 594 NCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQF 629
+C G+ G TC+ G C CK G C+ C F
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 60.5 bits (140), Expect = 1e-07
Identities = 42/157 (26%), Positives = 61/157 (38%), Gaps = 30/157 (19%)
Query: 408 CNLNGTEGEHCTPTDG--LCPCKYNYAGKSCEICEDGYY-----------SPECKNCECN 454
C NG T G +C C++ G C C+ Y S C C CN
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 455 TVGS---VSYVCDKLTGD-----C-TCKSKYSGRTCNQCQAGYYNYP--------TCKPC 497
+ +L+G C C+ +GR C+ C+ G+Y P C+ C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 498 NCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY 534
+C G C+ +GQC CK G G C++C G+
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 59.7 bits (138), Expect = 2e-07
Identities = 38/157 (24%), Positives = 62/157 (39%), Gaps = 23/157 (14%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCD 500
C+CN S + + C C+ G C +C+ Y + P C C+C+
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 501 TSGTEPSICDDV--------SGQCI-CKAGFGGPRCDQCLSGYYM---QVLGRERQCVPC 548
++ G C+ C+ G C C G+Y + L R C C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 549 NCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGY 584
+C P G+ +C+ G+C C G C++C+PG+
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 57.6 bits (133), Expect = 8e-07
Identities = 51/172 (29%), Positives = 67/172 (38%), Gaps = 31/172 (18%)
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGD----- 1920
TDL G CK C+G+ + D+ C + T G C C P FY D
Sbjct: 247 TDLQVGGRCK---CNGHASRC---LLDTQGHLICDCRHGTEGPDCGRCKP-FYCDRPWQR 299
Query: 1921 --AIFSKNCTACICD------EFGMA----DCDSTTGTCV-CRPGVIGEKCDRCAPDHW- 1966
A S C AC C+ F M + G C+ CR G C C +
Sbjct: 300 ATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR 359
Query: 1967 ----GLNTGLGCTPCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
L+ C C+C + + C+ GQC C GVTG C++CA GF
Sbjct: 360 DPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 56.8 bits (131), Expect = 1e-06
Identities = 45/157 (28%), Positives = 60/157 (38%), Gaps = 26/157 (16%)
Query: 1334 NSGARPCLCDFMGSTELECN--TFGGQCP-CKPNVIGRTCSACRTGYYGFPNCRPCHCPS 1390
N A CL D G +C T G C CKP R R C C C
Sbjct: 258 NGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQ--RATARESHACLACSCNG 315
Query: 1391 TAI-CDDN------------GMCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCN 1431
A C N G+C+ C N G +C C+ + +R C C+
Sbjct: 316 HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375
Query: 1432 CNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C+P+G G C +G+C C++ V G C+ C PG
Sbjct: 376 CHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAPG 410
Score = 56.4 bits (130), Expect = 2e-06
Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 24/134 (17%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGL---GCTPCNCGIASESTQCDDD-------- 1991
C CR G G C RC P + W T C C+C + + + +
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWN------YTKDGCDHCNCNTGYSVGFMCN-ATGQC 2042
G C C G+ C C GF+ + C C+C+ + G CN TGQC
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393
Query: 2043 ECLPGVIGEKCDRC 2056
C GV G C+RC
Sbjct: 394 PCKDGVTGLTCNRC 407
Score = 52.8 bits (121), Expect = 2e-05
Identities = 56/237 (23%), Positives = 86/237 (36%), Gaps = 37/237 (15%)
Query: 593 CNCDVSGSIGSTCDDNG--LCHCKSNFDGAKCDTCREQFYNYP----------ACEECNC 640
C C+ S D G +C C+ +G C C+ + + P AC C+C
Sbjct: 255 CKCNGHAS-RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSC 313
Query: 641 DPRGVTASFAG-----CGSVPAGELCQCKDRVQGRICNDCKPLYWN---LQEYNPFGCEQ 692
+ F G G C+ GR C+ C+ ++ + C
Sbjct: 314 NGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRA 373
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
C+C+ G CN +GQC CK V C++C GF + + V C + I G
Sbjct: 374 CDCHPVGAAGK--TCNQTTGQCPCKDGVTGLTCNRCAPGFQQ-SRSPVAPCVK--TPIPG 428
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQF---QYEVEDGVTQSGPVR 806
+++ C H C +P R Y +L +F Y V+ V G R
Sbjct: 429 PTEDSSPVQPQDCDSH-------C-KPARGSYRISLKKFCKKDYAVQVAVGARGEAR 477
Score = 47.6 bits (108), Expect = 8e-04
Identities = 34/114 (29%), Positives = 45/114 (39%), Gaps = 8/114 (7%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPC-LCDF--MGSTELECNTFGGQCPCKP 1363
C + + + CRE + S R C CD +G+ CN GQCPCK
Sbjct: 338 CLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKD 397
Query: 1364 NVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RCKP 1416
V G TC+ C G+ C T I G V+ ++CD CKP
Sbjct: 398 GVTGLTCNRCAPGFQQ-SRSPVAPCVKTPI---PGPTEDSSPVQPQDCDSHCKP 447
Score = 34.7 bits (76), Expect = 6.4
Identities = 23/81 (28%), Positives = 28/81 (34%), Gaps = 8/81 (9%)
Query: 1466 VPGHYAFPDCY---QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFN----- 1517
VP YA D +C CN H + + Q C C+ G C CK Y +
Sbjct: 240 VPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQR 299
Query: 1518 LQDDNPDGCTKCFCFGKTTRC 1538
C C C G RC
Sbjct: 300 ATARESHACLACSCNGHARRC 320
>AL353631-1|CAI16126.1| 522|Homo sapiens netrin G2 protein.
Length = 522
Score = 177 bits (430), Expect = 8e-43
Identities = 132/428 (30%), Positives = 190/428 (44%), Gaps = 56/428 (13%)
Query: 37 CDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+N HPP D T+WQS SR E N+T+ + + V
Sbjct: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDS----VICST 148
RP + VLEKS D G+T++P+Q++++ DC FG + + S V+C+
Sbjct: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
Query: 149 EYSKIVPLEDGEIPISLLNDR------PS----SNMYF---NSSVLQEWTRATNVRLRLL 195
EYS+ + + + DR P N+Y ++ L+E+ T++R+RLL
Sbjct: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
Query: 196 RTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCR 255
R LG V R++ +YFY+I +I + GRC CN HA+ C + G+L C
Sbjct: 258 RPA--LGGTY-VQREN---LYKYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CE 306
Query: 256 CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP---CNCHNHTTECTYDPEIDEKRLS 312
C+HNT GP C KC F + WR P C C+ H+ C+Y ID
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCECYGHSNRCSY---ID----- 358
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
+ C++C+HNT G +C CR YYR D+ +VC C C+ S +
Sbjct: 359 ------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 412
Query: 373 EEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPTDGLCPCKY 429
E+G CECR P C C ++ C P C+ L G C C C
Sbjct: 413 CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQ-RCACPR 471
Query: 430 NYAGKSCE 437
Y G CE
Sbjct: 472 GYTGVRCE 479
Score = 86.2 bits (204), Expect = 2e-15
Identities = 63/214 (29%), Positives = 84/214 (39%), Gaps = 19/214 (8%)
Query: 428 KYNYAGKSCEI---CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTC-KSKYSGRTCNQ 483
KY YA + E+ C+ ++ C E GS+ C+ T C K K + RT +
Sbjct: 273 KYFYAISNIEVIGRCKCNLHANLCSMRE----GSLQCECEHNTTGPDCGKCKKNFRTRSW 328
Query: 484 CQAGYYNYPTCKP---CNCDTSGTEPSICDDVSG-QCI-CKAGFGGPRCDQCLSGYYMQ- 537
Y P P C C S D ++ C+ CK G C C GYY
Sbjct: 329 RAGSYLPLPHGSPNAYCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNG 388
Query: 538 --VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
L E C+ CNC+ GS C+ G C C G +CD C P +Y C C
Sbjct: 389 SAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 448
Query: 596 DVSGSI---GSTCDDNGLCHCKSNFDGAKCDTCR 626
D + G TC N C C + G +C+ R
Sbjct: 449 DDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 482
Score = 83.8 bits (198), Expect = 1e-14
Identities = 62/205 (30%), Positives = 88/205 (42%), Gaps = 35/205 (17%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 281 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
Query: 405 P-CTCNLNGTEGEHCTPTDGL----C-PCKYNYAGKSCEICEDGYY---SPE------CK 449
P C G C+ D L C CK+N G+ C+ C GYY S E C
Sbjct: 341 PNAYCECYG-HSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 399
Query: 450 NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
C CN +GSV C++ TG C C+ +G C+ C +Y C P CD + +C
Sbjct: 400 ECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCD---DDQLLC 455
Query: 510 DD-----VSGQCICKAGFGGPRCDQ 529
+ + +C C G+ G RC+Q
Sbjct: 456 QNGGTCLQNQRCACPRGYTGVRCEQ 480
Score = 79.4 bits (187), Expect = 2e-13
Identities = 63/200 (31%), Positives = 84/200 (42%), Gaps = 24/200 (12%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGY----YGIPEDTDLHTGDYCKPCNC 1879
N A C + E GSL C C+ G C C + + L G C C
Sbjct: 290 NLHANLCSMRE-GSL-QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCEC 347
Query: 1880 SGNINPQDPGSCDSING-DCLKCVNNTAGAACNLCAPGFY--GDA-IFSKN-CTACICDE 1934
G+ N D +N C+ C +NT G C C G+Y G A + +N C C C++
Sbjct: 348 YGHSNRCS--YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ 405
Query: 1935 FGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD--- 1990
G D + TG C CR G G KCD C P H+ GC P C + C +
Sbjct: 406 IGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVCD--DDQLLCQNGGT 460
Query: 1991 --DNGQCRCAKGVTGKQCDQ 2008
N +C C +G TG +C+Q
Sbjct: 461 CLQNQRCACPRGYTGVRCEQ 480
Score = 71.3 bits (167), Expect = 6e-11
Identities = 61/191 (31%), Positives = 80/191 (41%), Gaps = 28/191 (14%)
Query: 1341 LCDFM-GSTELEC--NTFGGQC-PCKPNVIGRTCSACRTGYYGFPNCRP---CHCPSTAI 1393
LC GS + EC NT G C CK N RT S Y P+ P C C +
Sbjct: 295 LCSMREGSLQCECEHNTTGPDCGKCKKNF--RTRSWRAGSYLPLPHGSPNAYCECYGHSN 352
Query: 1394 -CD-----DNGMCI-CPKNVEGENCDRCK-PYTFN----FDVQRGCDDCNCNPLGVVGNQ 1441
C + C+ C N G++C C+ Y N D + C +CNCN +G V ++
Sbjct: 353 RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 412
Query: 1442 LQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD---VCDQNTAQCY 1498
C ++G C CRE G CD C+P HY CY C+ C QN +C
Sbjct: 413 --CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN-QRCA 468
Query: 1499 CKTNVRGQACD 1509
C G C+
Sbjct: 469 CPRGYTGVRCE 479
Score = 65.7 bits (153), Expect = 3e-09
Identities = 53/206 (25%), Positives = 72/206 (34%), Gaps = 32/206 (15%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C C+ S+ + S QC C+ GP C +C + + R +P P GS
Sbjct: 287 CKCNLHANLCSMREG-SLQCECEHNTTGPDCGKCKKNFRTRSW-RAGSYLPL---PHGSP 341
Query: 557 STSCSADGKCN---------------CLTNFGGAQCDQCSPGYYKYPD--------CLSC 593
+ C G N C N G C C GYY+ C+ C
Sbjct: 342 NAYCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIEC 401
Query: 594 NCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCG 653
NC+ GS+ C++ G C C+ G KCD C Y C CD + G
Sbjct: 402 NCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ--NGG 459
Query: 654 SVPAGELCQCKDRVQGRICND--CKP 677
+ + C C G C C P
Sbjct: 460 TCLQNQRCACPRGYTGVRCEQPRCDP 485
Score = 65.3 bits (152), Expect = 4e-09
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 654 SVPAGEL-CQCKDRVQGRICNDCKPLY----WNLQEYNPF--GCEQCNCNLAGTLNSLGA 706
S+ G L C+C+ G C CK + W Y P G C G N
Sbjct: 297 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCECYGHSNRCSY 356
Query: 707 CNTKSG-QCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ + CV CK + + C C G+YR + +D C EC+C+ GS+ + C++T
Sbjct: 357 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNET 416
Query: 762 TGQCHCHSRVEGRRCDQPIRAHYF 785
G C C G +CD + HY+
Sbjct: 417 -GFCECREGAAGPKCDDCLPTHYW 439
Score = 61.3 bits (142), Expect = 6e-08
Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 27/144 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGH----YRLPSGFCVP-------CQCNGHSDQCD----VNTG 1779
+C+C G C +C + +R S +P C+C GHS++C +N
Sbjct: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCECYGHSNRCSYIDFLNVV 363
Query: 1780 ICLNCADNTIGDHCEFCMSGYH--GDATVGTPRDCLICACPMPYPSNNFALSCD-LSENG 1836
C++C NT G HC+ C GY+ G A + C+ C C N D +E G
Sbjct: 364 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC------NQIGSVHDRCNETG 417
Query: 1837 SLISCNCQPGYGGARCEYCAAGYY 1860
C C+ G G +C+ C +Y
Sbjct: 418 ---FCECREGAAGPKCDDCLPTHY 438
Score = 60.5 bits (140), Expect = 1e-07
Identities = 41/147 (27%), Positives = 59/147 (40%), Gaps = 23/147 (15%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA------- 1452
C C N G +C +CK F R P G +C S +C+
Sbjct: 305 CECEHNTTGPDCGKCKK-NFRTRSWRAGSYLPL-PHGSPNAYCECYGHSNRCSYIDFLNV 362
Query: 1453 -----CRENVRGRVCDHCVPGHYA-----FPD---CYQCTCNRHGTTYDVCDQNTAQCYC 1499
C+ N RG+ C HC G+Y D C +C CN+ G+ +D C++ T C C
Sbjct: 363 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCEC 421
Query: 1500 KTNVRGQACDTCKEEYFNLQDDNPDGC 1526
+ G CD C ++ Q P+ C
Sbjct: 422 REGAAGPKCDDCLPTHYWRQGCYPNVC 448
Score = 58.8 bits (136), Expect = 3e-07
Identities = 49/205 (23%), Positives = 79/205 (38%), Gaps = 28/205 (13%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP-----------ACEECNCD 641
C C++ ++ S + + C C+ N G C C++ F C+
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCE 346
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN-----LQEYNPFGCEQCNCN 696
G + + + CK +G+ C C+ Y+ L + N C +CNCN
Sbjct: 347 CYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV--CIECNCN 404
Query: 697 LAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDN 756
G+++ CN ++G C C++ +CD CL Y Q GC CD +
Sbjct: 405 QIGSVHD--RCN-ETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVCDDDQLLCQ 456
Query: 757 NCDKT--TGQCHCHSRVEGRRCDQP 779
N +C C G RC+QP
Sbjct: 457 NGGTCLQNQRCACPRGYTGVRCEQP 481
Score = 58.0 bits (134), Expect = 6e-07
Identities = 59/226 (26%), Positives = 87/226 (38%), Gaps = 34/226 (15%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFY------GDAI-FSKN 1926
CK CN N+ GS C +C +NT G C C F G +
Sbjct: 287 CK-CNLHANLCSMREGSLQ-----C-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG 339
Query: 1927 CTACICDEFGMADCDS-----TTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCT 1975
C+ +G ++ S TCV C+ G+ C C ++ L+ C
Sbjct: 340 SPNAYCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 399
Query: 1976 PCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-- 2032
CNC I S +C++ G C C +G G +CD C +Y + GC C+ +
Sbjct: 400 ECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQ 456
Query: 2033 -GFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
G C +C C G G +C++ R +G L+CD A
Sbjct: 457 NGGTCLQNQRCACPRGYTGVRCEQ--PRCDPADDDGGLDCDRAPGA 500
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-----CPSTA 1392
C C+ +GS CN G C C+ G C C +Y C P C C +
Sbjct: 401 CNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 459
Query: 1393 ICDDNGMCICPKNVEGENCD--RCKP 1416
C N C CP+ G C+ RC P
Sbjct: 460 TCLQNQRCACPRGYTGVRCEQPRCDP 485
Score = 43.6 bits (98), Expect = 0.014
Identities = 37/126 (29%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 1420 NFDVQRGCDDCN--CNPLGVVGNQLQCEA-------DSGKCACRENVRGRVCDHCVPGHY 1470
N +V C CN N + LQCE D GKC R +P +
Sbjct: 280 NIEVIGRCK-CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPH 338
Query: 1471 AFPDCYQCTCNRHGTTYDVCD-QNTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDG 1525
P+ Y C C H D N C CK N RGQ C C+ Y+ + + D+ +
Sbjct: 339 GSPNAY-CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 397
Query: 1526 CTKCFC 1531
C +C C
Sbjct: 398 CIECNC 403
Score = 36.3 bits (80), Expect = 2.1
Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 13/73 (17%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE----------EYFNLQDDNPDGC 1526
+C CN H + + + QC C+ N G C CK+ Y L +P+
Sbjct: 286 RCKCNLHANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPN-- 342
Query: 1527 TKCFCFGKTTRCS 1539
C C+G + RCS
Sbjct: 343 AYCECYGHSNRCS 355
>AL159997-4|CAI40855.1| 522|Homo sapiens netrin G2 protein.
Length = 522
Score = 177 bits (430), Expect = 8e-43
Identities = 132/428 (30%), Positives = 190/428 (44%), Gaps = 56/428 (13%)
Query: 37 CDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+N HPP D T+WQS SR E N+T+ + + V
Sbjct: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDS----VICST 148
RP + VLEKS D G+T++P+Q++++ DC FG + + S V+C+
Sbjct: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
Query: 149 EYSKIVPLEDGEIPISLLNDR------PS----SNMYF---NSSVLQEWTRATNVRLRLL 195
EYS+ + + + DR P N+Y ++ L+E+ T++R+RLL
Sbjct: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
Query: 196 RTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCR 255
R LG V R++ +YFY+I +I + GRC CN HA+ C + G+L C
Sbjct: 258 RPA--LGGTY-VQREN---LYKYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CE 306
Query: 256 CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP---CNCHNHTTECTYDPEIDEKRLS 312
C+HNT GP C KC F + WR P C C+ H+ C+Y ID
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCECYGHSNRCSY---ID----- 358
Query: 313 LDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
+ C++C+HNT G +C CR YYR D+ +VC C C+ S +
Sbjct: 359 ------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 412
Query: 373 EEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPTDGLCPCKY 429
E+G CECR P C C ++ C P C+ L G C C C
Sbjct: 413 CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQ-RCACPR 471
Query: 430 NYAGKSCE 437
Y G CE
Sbjct: 472 GYTGVRCE 479
Score = 86.2 bits (204), Expect = 2e-15
Identities = 63/214 (29%), Positives = 84/214 (39%), Gaps = 19/214 (8%)
Query: 428 KYNYAGKSCEI---CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTC-KSKYSGRTCNQ 483
KY YA + E+ C+ ++ C E GS+ C+ T C K K + RT +
Sbjct: 273 KYFYAISNIEVIGRCKCNLHANLCSMRE----GSLQCECEHNTTGPDCGKCKKNFRTRSW 328
Query: 484 CQAGYYNYPTCKP---CNCDTSGTEPSICDDVSG-QCI-CKAGFGGPRCDQCLSGYYMQ- 537
Y P P C C S D ++ C+ CK G C C GYY
Sbjct: 329 RAGSYLPLPHGSPNAYCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNG 388
Query: 538 --VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
L E C+ CNC+ GS C+ G C C G +CD C P +Y C C
Sbjct: 389 SAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 448
Query: 596 DVSGSI---GSTCDDNGLCHCKSNFDGAKCDTCR 626
D + G TC N C C + G +C+ R
Sbjct: 449 DDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 482
Score = 83.8 bits (198), Expect = 1e-14
Identities = 62/205 (30%), Positives = 88/205 (42%), Gaps = 35/205 (17%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 281 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
Query: 405 P-CTCNLNGTEGEHCTPTDGL----C-PCKYNYAGKSCEICEDGYY---SPE------CK 449
P C G C+ D L C CK+N G+ C+ C GYY S E C
Sbjct: 341 PNAYCECYG-HSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 399
Query: 450 NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
C CN +GSV C++ TG C C+ +G C+ C +Y C P CD + +C
Sbjct: 400 ECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCD---DDQLLC 455
Query: 510 DD-----VSGQCICKAGFGGPRCDQ 529
+ + +C C G+ G RC+Q
Sbjct: 456 QNGGTCLQNQRCACPRGYTGVRCEQ 480
Score = 79.4 bits (187), Expect = 2e-13
Identities = 63/200 (31%), Positives = 84/200 (42%), Gaps = 24/200 (12%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGY----YGIPEDTDLHTGDYCKPCNC 1879
N A C + E GSL C C+ G C C + + L G C C
Sbjct: 290 NLHANLCSMRE-GSL-QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCEC 347
Query: 1880 SGNINPQDPGSCDSING-DCLKCVNNTAGAACNLCAPGFY--GDA-IFSKN-CTACICDE 1934
G+ N D +N C+ C +NT G C C G+Y G A + +N C C C++
Sbjct: 348 YGHSNRCS--YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ 405
Query: 1935 FGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD--- 1990
G D + TG C CR G G KCD C P H+ GC P C + C +
Sbjct: 406 IGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVCD--DDQLLCQNGGT 460
Query: 1991 --DNGQCRCAKGVTGKQCDQ 2008
N +C C +G TG +C+Q
Sbjct: 461 CLQNQRCACPRGYTGVRCEQ 480
Score = 71.3 bits (167), Expect = 6e-11
Identities = 61/191 (31%), Positives = 80/191 (41%), Gaps = 28/191 (14%)
Query: 1341 LCDFM-GSTELEC--NTFGGQC-PCKPNVIGRTCSACRTGYYGFPNCRP---CHCPSTAI 1393
LC GS + EC NT G C CK N RT S Y P+ P C C +
Sbjct: 295 LCSMREGSLQCECEHNTTGPDCGKCKKNF--RTRSWRAGSYLPLPHGSPNAYCECYGHSN 352
Query: 1394 -CD-----DNGMCI-CPKNVEGENCDRCK-PYTFN----FDVQRGCDDCNCNPLGVVGNQ 1441
C + C+ C N G++C C+ Y N D + C +CNCN +G V ++
Sbjct: 353 RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 412
Query: 1442 LQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD---VCDQNTAQCY 1498
C ++G C CRE G CD C+P HY CY C+ C QN +C
Sbjct: 413 --CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN-QRCA 468
Query: 1499 CKTNVRGQACD 1509
C G C+
Sbjct: 469 CPRGYTGVRCE 479
Score = 65.7 bits (153), Expect = 3e-09
Identities = 53/206 (25%), Positives = 72/206 (34%), Gaps = 32/206 (15%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C C+ S+ + S QC C+ GP C +C + + R +P P GS
Sbjct: 287 CKCNLHANLCSMREG-SLQCECEHNTTGPDCGKCKKNFRTRSW-RAGSYLPL---PHGSP 341
Query: 557 STSCSADGKCN---------------CLTNFGGAQCDQCSPGYYKYPD--------CLSC 593
+ C G N C N G C C GYY+ C+ C
Sbjct: 342 NAYCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIEC 401
Query: 594 NCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCG 653
NC+ GS+ C++ G C C+ G KCD C Y C CD + G
Sbjct: 402 NCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ--NGG 459
Query: 654 SVPAGELCQCKDRVQGRICND--CKP 677
+ + C C G C C P
Sbjct: 460 TCLQNQRCACPRGYTGVRCEQPRCDP 485
Score = 65.3 bits (152), Expect = 4e-09
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 654 SVPAGEL-CQCKDRVQGRICNDCKPLY----WNLQEYNPF--GCEQCNCNLAGTLNSLGA 706
S+ G L C+C+ G C CK + W Y P G C G N
Sbjct: 297 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCECYGHSNRCSY 356
Query: 707 CNTKSG-QCV-CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ + CV CK + + C C G+YR + +D C EC+C+ GS+ + C++T
Sbjct: 357 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNET 416
Query: 762 TGQCHCHSRVEGRRCDQPIRAHYF 785
G C C G +CD + HY+
Sbjct: 417 -GFCECREGAAGPKCDDCLPTHYW 439
Score = 61.3 bits (142), Expect = 6e-08
Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 27/144 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGH----YRLPSGFCVP-------CQCNGHSDQCD----VNTG 1779
+C+C G C +C + +R S +P C+C GHS++C +N
Sbjct: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCECYGHSNRCSYIDFLNVV 363
Query: 1780 ICLNCADNTIGDHCEFCMSGYH--GDATVGTPRDCLICACPMPYPSNNFALSCD-LSENG 1836
C++C NT G HC+ C GY+ G A + C+ C C N D +E G
Sbjct: 364 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC------NQIGSVHDRCNETG 417
Query: 1837 SLISCNCQPGYGGARCEYCAAGYY 1860
C C+ G G +C+ C +Y
Sbjct: 418 ---FCECREGAAGPKCDDCLPTHY 438
Score = 60.5 bits (140), Expect = 1e-07
Identities = 41/147 (27%), Positives = 59/147 (40%), Gaps = 23/147 (15%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA------- 1452
C C N G +C +CK F R P G +C S +C+
Sbjct: 305 CECEHNTTGPDCGKCKK-NFRTRSWRAGSYLPL-PHGSPNAYCECYGHSNRCSYIDFLNV 362
Query: 1453 -----CRENVRGRVCDHCVPGHYA-----FPD---CYQCTCNRHGTTYDVCDQNTAQCYC 1499
C+ N RG+ C HC G+Y D C +C CN+ G+ +D C++ T C C
Sbjct: 363 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCEC 421
Query: 1500 KTNVRGQACDTCKEEYFNLQDDNPDGC 1526
+ G CD C ++ Q P+ C
Sbjct: 422 REGAAGPKCDDCLPTHYWRQGCYPNVC 448
Score = 58.8 bits (136), Expect = 3e-07
Identities = 49/205 (23%), Positives = 79/205 (38%), Gaps = 28/205 (13%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP-----------ACEECNCD 641
C C++ ++ S + + C C+ N G C C++ F C+
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAYCE 346
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN-----LQEYNPFGCEQCNCN 696
G + + + CK +G+ C C+ Y+ L + N C +CNCN
Sbjct: 347 CYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV--CIECNCN 404
Query: 697 LAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDN 756
G+++ CN ++G C C++ +CD CL Y Q GC CD +
Sbjct: 405 QIGSVHD--RCN-ETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVCDDDQLLCQ 456
Query: 757 NCDKT--TGQCHCHSRVEGRRCDQP 779
N +C C G RC+QP
Sbjct: 457 NGGTCLQNQRCACPRGYTGVRCEQP 481
Score = 58.0 bits (134), Expect = 6e-07
Identities = 59/226 (26%), Positives = 87/226 (38%), Gaps = 34/226 (15%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFY------GDAI-FSKN 1926
CK CN N+ GS C +C +NT G C C F G +
Sbjct: 287 CK-CNLHANLCSMREGSLQ-----C-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG 339
Query: 1927 CTACICDEFGMADCDS-----TTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCT 1975
C+ +G ++ S TCV C+ G+ C C ++ L+ C
Sbjct: 340 SPNAYCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 399
Query: 1976 PCNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV-- 2032
CNC I S +C++ G C C +G G +CD C +Y + GC C+ +
Sbjct: 400 ECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQ 456
Query: 2033 -GFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
G C +C C G G +C++ R +G L+CD A
Sbjct: 457 NGGTCLQNQRCACPRGYTGVRCEQ--PRCDPADDDGGLDCDRAPGA 500
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-----CPSTA 1392
C C+ +GS CN G C C+ G C C +Y C P C C +
Sbjct: 401 CNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 459
Query: 1393 ICDDNGMCICPKNVEGENCD--RCKP 1416
C N C CP+ G C+ RC P
Sbjct: 460 TCLQNQRCACPRGYTGVRCEQPRCDP 485
Score = 43.6 bits (98), Expect = 0.014
Identities = 37/126 (29%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 1420 NFDVQRGCDDCN--CNPLGVVGNQLQCEA-------DSGKCACRENVRGRVCDHCVPGHY 1470
N +V C CN N + LQCE D GKC R +P +
Sbjct: 280 NIEVIGRCK-CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPH 338
Query: 1471 AFPDCYQCTCNRHGTTYDVCD-QNTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDG 1525
P+ Y C C H D N C CK N RGQ C C+ Y+ + + D+ +
Sbjct: 339 GSPNAY-CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 397
Query: 1526 CTKCFC 1531
C +C C
Sbjct: 398 CIECNC 403
Score = 36.3 bits (80), Expect = 2.1
Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 13/73 (17%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE----------EYFNLQDDNPDGC 1526
+C CN H + + + QC C+ N G C CK+ Y L +P+
Sbjct: 286 RCKCNLHANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPN-- 342
Query: 1527 TKCFCFGKTTRCS 1539
C C+G + RCS
Sbjct: 343 AYCECYGHSNRCS 355
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 176 bits (429), Expect = 1e-42
Identities = 136/434 (31%), Positives = 175/434 (40%), Gaps = 66/434 (15%)
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKP-CTCNLNGT 413
D Q CQC + C+ +G C C P + C C G P C+ C C NG
Sbjct: 190 DCHQRCQCQ---NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQ-NGG 244
Query: 414 EGEHCTPTDGLCPCKYNYAGKSC-EICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCT 471
H T G C C + G C + C +G + C + C+C+ G+ CD TG C
Sbjct: 245 VCHHVT---GECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGT----CDAATGQCH 297
Query: 472 CKSKYSGRTC-NQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQC 530
C Y+G C ++C G Y + C C G C VSG C+C+AGF G RC+
Sbjct: 298 CSPGYTGERCQDECPVGTYGVLCAETCQCVNGGK----CYHVSGACLCEAGFAGERCEAR 353
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPD 589
L + + +++C PC+ + T S G+C C + G C++ CSPG+Y
Sbjct: 354 LCPEGLYGIKCDKRC-PCHLENTHSCH---PMSGECACKPGWSGLYCNETCSPGFYGEAC 409
Query: 590 CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTA 647
C+C G+ CD G C C F G C T C Y C C V +
Sbjct: 410 QQICSC----QNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCS 465
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLG 705
P C CK G C+ C W FGC C C LN G
Sbjct: 466 --------PVDGSCTCKAGWHGVDCSIRCPSGTWG------FGCNLTCQC-----LNG-G 505
Query: 706 ACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTG 763
ACNT G C C +C+ C DG Y L C E CDC S + C TTG
Sbjct: 506 ACNTLDGTCTCAPGWRGEKCELPCQDGTYGL------NCAERCDC----SHADGCHPTTG 555
Query: 764 QCHCHSRVEGRRCD 777
C C G CD
Sbjct: 556 HCRCLPGWSGVHCD 569
Score = 168 bits (409), Expect = 3e-40
Identities = 144/495 (29%), Positives = 196/495 (39%), Gaps = 86/495 (17%)
Query: 323 GKCLNCQHNTEGINCNK-CRPTYYRPYGKRWDELDVCQP-CQCDPHFSTGNCEEESGRCE 380
G+C C+ G+ CN+ C P +Y + CQ C C + +C+ +G+C
Sbjct: 383 GECA-CKPGWSGLYCNETCSPGFYG---------EACQQICSCQ---NGADCDSVTGKCT 429
Query: 381 CRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI- 438
C P F+ DCS+ C G + C C + C+P DG C CK + G C I
Sbjct: 430 CAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAV----CSPVDGSCTCKAGWHGVDCSIR 485
Query: 439 CEDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKP 496
C G + C C+C G+ C+ L G CTC + G C CQ G Y +
Sbjct: 486 CPSGTWGFGCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAER 541
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGS 555
C+C + C +G C C G+ G CD C G + +PC C
Sbjct: 542 CDCSHADG----CHPTTGHCRCLPGWSGVHCDSVCAEGRW-----GPNCSLPCYC----K 588
Query: 556 TSTSCSAD-GKCNCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHC 613
SCS D G C C F G C + CSPG+Y + +C V S G GLC C
Sbjct: 589 NGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS-GPCHHITGLCDC 647
Query: 614 KSNFDGAKCD----------------TCREQFYNYPACEECNCDPRGVTASFAG-CGSVP 656
F GA C+ TC P C C P + + + C
Sbjct: 648 LPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAH 707
Query: 657 AGELC--QCKDRVQGRICN------DCKPLYWNLQ--EYNPFGCEQCNCNLAGTLNSLGA 706
G C C G C+ C P + L + P G +C L +
Sbjct: 708 WGPNCIHTCNCH-NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGAD 766
Query: 707 CNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTE-CDCDIGGSIDNN-CDKTTG 763
C+ SGQC C+ R C+Q C G Y +GC + CDC ++N+ CD TG
Sbjct: 767 CDHISGQCTCRTGFMGRHCEQKCPSGTYG------YGCRQICDC-----LNNSTCDHITG 815
Query: 764 QCHCHSRVEGRRCDQ 778
C+C +G RCDQ
Sbjct: 816 TCYCSPGWKGARCDQ 830
Score = 157 bits (380), Expect = 9e-37
Identities = 137/478 (28%), Positives = 188/478 (39%), Gaps = 76/478 (15%)
Query: 315 INGRYEGGGKCLNCQHNTEGINCNK-CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
++GR C C+ G NC+ C ++ P+ CQC + C
Sbjct: 114 VHGRCIAPNTC-QCEPGWGGTNCSSACDGDHWGPH--------CTSRCQCK---NGALCN 161
Query: 374 EESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
+G C C F+ C C G + + C C NG +H T G C C Y
Sbjct: 162 PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ-NGATCDHVT---GECRCPPGYT 217
Query: 433 GKSCE-ICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYY 489
G CE +C G + P+C+ C C G VC +TG+C+C S + G C Q C G +
Sbjct: 218 GAFCEDLCPPGKHGPQCEQRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQPCPEGRF 273
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPC 548
+ C C GT CD +GQC C G+ G RC D+C G Y + QCV
Sbjct: 274 GKNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCV-- 327
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLSCNCDVSGSIGSTCD 606
G S G C C F G +C+ C G Y C C + + +C
Sbjct: 328 ----NGGKCYHVS--GACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENT--HSCH 379
Query: 607 D-NGLCHCKSNFDGAKC-DTCREQFYNYPACEE-CNCDPRGVTASFAGCGSVPAGELCQC 663
+G C CK + G C +TC FY AC++ C+C + A C SV G+ C C
Sbjct: 380 PMSGECACKPGWSGLYCNETCSPGFYG-EACQQICSCQ------NGADCDSV-TGK-CTC 430
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
+G C+ PL G NC+ + C+ G C CK
Sbjct: 431 APGFKGIDCSTPCPL----------GTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
Query: 724 QCD-QCLDGFYRLQTNDVFGCT-ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C +C G + FGC C C GG+ C+ G C C G +C+ P
Sbjct: 481 DCSIRCPSGTWG------FGCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELP 528
Score = 155 bits (375), Expect = 4e-36
Identities = 155/570 (27%), Positives = 225/570 (39%), Gaps = 78/570 (13%)
Query: 255 RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP----CNCHNHTTECTYDPEIDEKR 310
RC+ T G C++ C Q C P C + + P+ +++
Sbjct: 181 RCEQGTYGNDCHQRCQC--QNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRC 238
Query: 311 LSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG 370
+ + G+C +C G C + P +GK + Q CQC + G
Sbjct: 239 PCQNGGVCHHVTGEC-SCPSGWMGTVCGQ--PCPEGRFGK-----NCSQECQCH---NGG 287
Query: 371 NCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKY 429
C+ +G+C C P + C C G + + C C G C G C C+
Sbjct: 288 TCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQC----VNGGKCYHVSGACLCEA 343
Query: 430 NYAGKSCE--ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQ 485
+AG+ CE +C +G Y +C K C C+ + S C ++G+C CK +SG CN+ C
Sbjct: 344 GFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS--CHPMSGECACKPGWSGLYCNETCS 401
Query: 486 AGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQ 544
G+Y + C+C +G + CD V+G+C C GF G C C G Y + R
Sbjct: 402 PGFYGEACQQICSCQ-NGAD---CDSVTGKCTCAPGFKGIDCSTPCPLGTY-GINCSSR- 455
Query: 545 CVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCD-QCSPGYYKYPDCLSCNCDVSGSIG 602
C C CS DG C C + G C +C G + + L+C C ++G
Sbjct: 456 ---CGC----KNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQC-LNGGAC 507
Query: 603 STCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPR-GVTASFAGCGSVPAGEL 660
+T D G C C + G KC+ C++ Y E C+C G + C +P
Sbjct: 508 NTLD--GTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSG 565
Query: 661 CQCKDR-VQGRICNDCK-PLYW-NLQEYNPF-GCEQCNCNLAGT----LNSLG----ACN 708
C +GR +C P Y N +P G +C GT + S G C+
Sbjct: 566 VHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCS 625
Query: 709 TKSGQCVCKQ---HVGERQCDQCLDGFYRLQTNDV-----FG--CTE-CDCDIGGSIDNN 757
QCV H CD CL GF N+V FG C C C G+
Sbjct: 626 QTCPQCVHSSGPCHHITGLCD-CLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGT---- 680
Query: 758 CDKTTGQCHCHSRVEGRRCDQPI-RAHYFP 786
C+ C C+ G C QP AH+ P
Sbjct: 681 CNPIDRSCQCYPGWIGSDCSQPCPPAHWGP 710
Score = 149 bits (362), Expect = 1e-34
Identities = 122/433 (28%), Positives = 175/433 (40%), Gaps = 65/433 (15%)
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKP-CTCNLNGTE 414
++C P C G C + C+C P + +CSS G P+C C C
Sbjct: 103 EMCVP-HCADKCVHGRCIAPN-TCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCK----N 156
Query: 415 GEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTC 472
G C P G C C + G CE CE G Y +C + C+C CD +TG+C C
Sbjct: 157 GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQN----GATCDHVTGECRC 212
Query: 473 KSKYSGRTCNQ-CQAGYYNYPTCKP-CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ- 529
Y+G C C G + P C+ C C G +C V+G+C C +G+ G C Q
Sbjct: 213 PPGYTGAFCEDLCPPGKHG-PQCEQRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQP 267
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC-DQCSPGYYKYP 588
C G + + +E C C G T +A G+C+C + G +C D+C G Y
Sbjct: 268 CPEGRFGKNCSQE-----CQCHNGG---TCDAATGQCHCSPGYTGERCQDECPVGTYGVL 319
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEECNCDPRGVT 646
+C C V+G G +G C C++ F G +C+ C E Y + C C
Sbjct: 320 CAETCQC-VNG--GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTH 376
Query: 647 ASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGTLNSL 704
+ C + +GE C CK G CN+ C P ++ C+Q C+C
Sbjct: 377 S----CHPM-SGE-CACKPGWSGLYCNETCSPGFYG------EACQQICSCQNGAD---- 420
Query: 705 GACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
C++ +G+C C C C G Y + + GC D C G
Sbjct: 421 --CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN---------DAVCSPVDG 469
Query: 764 QCHCHSRVEGRRC 776
C C + G C
Sbjct: 470 SCTCKAGWHGVDC 482
Score = 134 bits (323), Expect = 8e-30
Identities = 109/399 (27%), Positives = 160/399 (40%), Gaps = 58/399 (14%)
Query: 391 SSCAYGYFDYPN-CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPEC 448
S C G+++ C P C G P C C+ + G +C C+ ++ P C
Sbjct: 92 SQCCPGFYESGEMCVP-HCADKCVHGRCIAPNT--CQCEPGWGGTNCSSACDGDHWGPHC 148
Query: 449 KN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKPCNCDTSGTEP 506
+ C+C +C+ +TG C C + + G C ++C+ G Y + C C T
Sbjct: 149 TSRCQCKN----GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGAT-- 202
Query: 507 SICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK 565
CD V+G+C C G+ G C D C G + E++C PC + G+
Sbjct: 203 --CDHVTGECRCPPGYTGAFCEDLCPPGKHGPQC--EQRC-PCQ-----NGGVCHHVTGE 252
Query: 566 CNCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKC- 622
C+C + + G C Q C G + C C G TCD G CHC + G +C
Sbjct: 253 CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGG----TCDAATGQCHCSPGYTGERCQ 308
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL 682
D C Y E C C G +G AG +R + R+C + LY
Sbjct: 309 DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGF---AGERCEARLCPE--GLYG-- 361
Query: 683 QEYNPFGCEQ-CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDV 740
C++ C C+L T +C+ SG+C CK C++ C GFY +
Sbjct: 362 -----IKCDKRCPCHLENT----HSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQI 412
Query: 741 FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C C G +CD TG+C C +G C P
Sbjct: 413 -----CSCQNGA----DCDSVTGKCTCAPGFKGIDCSTP 442
Score = 133 bits (322), Expect = 1e-29
Identities = 110/329 (33%), Positives = 143/329 (43%), Gaps = 63/329 (19%)
Query: 1735 ECQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC CP + G C Q C EG R CQC+ + CD TG C +C+ G+ C
Sbjct: 252 ECSCPSGWMGTVCGQPCPEG--RFGKNCSQECQCH-NGGTCDAATGQC-HCSPGYTGERC 307
Query: 1794 EF-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G +G T C C N +S +C C+ G+ G RC
Sbjct: 308 QDECPVGTYGVLCAET------CQCV------NGGKCYHVSG-----ACLCEAGFAGERC 350
Query: 1853 E--YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
E C G YGI D K C C + ++ SC ++G+C C +G C
Sbjct: 351 EARLCPEGLYGIKCD---------KRCPC----HLENTHSCHPMSGECA-CKPGWSGLYC 396
Query: 1911 N-LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
N C+PGFYG+A C IC ADCDS TG C C PG G C P L
Sbjct: 397 NETCSPGFYGEA-----CQQ-ICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCP----LG 446
Query: 1970 T-GLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCD-HCNC 2026
T G+ C+ CG +++ C +G C C G G C +C +G W + GC+ C C
Sbjct: 447 TYGINCS-SRCGCKNDAV-CSPVDGSCTCKAGWHGVDCSIRCPSGTWGF---GCNLTCQC 501
Query: 2027 NTGYSVGFMCNA-TGQCECLPGVIGEKCD 2054
G + CN G C C PG GEKC+
Sbjct: 502 LNGGA----CNTLDGTCTCAPGWRGEKCE 526
Score = 132 bits (319), Expect = 2e-29
Identities = 103/358 (28%), Positives = 141/358 (39%), Gaps = 61/358 (17%)
Query: 362 QCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCK-PCTCNLNGTEGEHCT 419
+CD + G C +G C C P + C S CA G + PNC PC C G C+
Sbjct: 541 RCDCSHADG-CHPTTGHCRCLPGWSGVHCDSVCAEGRWG-PNCSLPCYCK----NGASCS 594
Query: 420 PTDGLCPCKYNYAGKSCE-ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSG 478
P DG+C C + G +C+ IC G+Y C C S C +TG C C ++G
Sbjct: 595 PDDGICECAPGFRGTTCQRICSPGFYGHRCSQT-CPQCVHSSGPCHHITGLCDCLPGFTG 653
Query: 479 RTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ-CLSGYYM 536
CN+ C +G + C C +GT C+ + C C G+ G C Q C ++
Sbjct: 654 ALCNEVCPSGRFGKNCAGICTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHWG 709
Query: 537 QVLGRERQCV-PCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQ-CSPGYYKYPDCLSC 593
C+ CNC CSA DG+C C + G C Q C G+Y L C
Sbjct: 710 P------NCIHTCNCH----NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALIC 759
Query: 594 NCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFAG 651
C G+ CD +G C C++ F G C+ C Y Y + C+C G
Sbjct: 760 QCQN----GADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITG 815
Query: 652 CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNT 709
C C +G C+Q + G LNSL +T
Sbjct: 816 T--------CYCSPGWKGA------------------RCDQAGVIIVGNLNSLSRTST 847
Score = 128 bits (308), Expect = 5e-28
Identities = 109/349 (31%), Positives = 142/349 (40%), Gaps = 53/349 (15%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDH 1792
C C + G CE C EG Y + PC N HS C +G C C G +
Sbjct: 339 CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS--CHPMSGECA-CKPGWSGLY 395
Query: 1793 C-EFCMSGYHGDA-----TVGTPRDC------LICA-------CPMPYPSNNFALSCDLS 1833
C E C G++G+A + DC CA C P P + ++C S
Sbjct: 396 CNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCS-S 454
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G C P G C+ AG++G+ +G + CN + + G+C++
Sbjct: 455 RCGCKNDAVCSPVDGSCTCK---AGWHGVDCSIRCPSGTWGFGCNLTCQC--LNGGACNT 509
Query: 1894 INGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
++G C C G C L C G YG NC A CD C TTG C C PG
Sbjct: 510 LDGTCT-CAPGWRGEKCELPCQDGTYG-----LNC-AERCDCSHADGCHPTTGHCRCLPG 562
Query: 1953 VIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CA 2010
G CD CA WG N L PC C C D+G C CA G G C + C+
Sbjct: 563 WSGVHCDSVCAEGRWGPNCSL---PCYC---KNGASCSPDDGICECAPGFRGTTCQRICS 616
Query: 2011 AGFWNY-TKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
GF+ + C C +S G + TG C+CLPG G C+ CP
Sbjct: 617 PGFYGHRCSQTCPQC----VHSSGPCHHITGLCDCLPGFTGALCNEVCP 661
Score = 115 bits (277), Expect = 3e-24
Identities = 113/365 (30%), Positives = 141/365 (38%), Gaps = 93/365 (25%)
Query: 1736 CQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C +RG CE C +G Y L C C+ H+D C TG C C G HC+
Sbjct: 514 CTCAPGWRGEKCELPCQDGTYGL--NCAERCDCS-HADGCHPTTGHC-RCLPGWSGVHCD 569
Query: 1795 -FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G G P L C C N A SC + C C PG+ G C+
Sbjct: 570 SVCAEGRWG------PNCSLPCYC------KNGA-SCSPDDG----ICECAPGFRGTTCQ 612
Query: 1854 -YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN- 1911
C+ G+YG C C S G C I G C C+ GA CN
Sbjct: 613 RICSPGFYGH------RCSQTCPQCVHSS-------GPCHHITGLC-DCLPGFTGALCNE 658
Query: 1912 LCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLN 1969
+C G +G KNC C C G C+ +C C PG IG C + C P HWG N
Sbjct: 659 VCPSGRFG-----KNCAGICTCTNNGT--CNPIDRSCQCYPGWIGSDCSQPCPPAHWGPN 711
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWN-------YTKDG- 2020
CNC C +G+C+C G TG C Q C GF+ ++G
Sbjct: 712 C---IHTCNC---HNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGA 765
Query: 2021 -CDH----CNCNTGY------------SVGFMC-------------NATGQCECLPGVIG 2050
CDH C C TG+ + G+ C + TG C C PG G
Sbjct: 766 DCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKG 825
Query: 2051 EKCDR 2055
+CD+
Sbjct: 826 ARCDQ 830
Score = 103 bits (247), Expect = 1e-20
Identities = 102/358 (28%), Positives = 128/358 (35%), Gaps = 73/358 (20%)
Query: 1736 CQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C +RG CE +C +G Y + CQC + CD TG C C G CE
Sbjct: 167 CHCAAGFRGWRCEDRCEQGTY--GNDCHQRCQCQ-NGATCDHVTGEC-RCPPGYTGAFCE 222
Query: 1795 -FCMSGYHG------------------DATVGTPRDCLICACPMPYPSNNFALSCDLS-- 1833
C G HG P + C P P F +C
Sbjct: 223 DLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQ 282
Query: 1834 -ENGSLI-----SCNCQPGYGGARC-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
NG C+C PGY G RC + C G YG+ + C C +N
Sbjct: 283 CHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVL---------CAETCQC---VN-- 328
Query: 1887 DPGSCDSINGDCLKCVNNTAGAAC--NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT 1944
G C ++G CL C AG C LC G YG K C C C +
Sbjct: 329 -GGKCYHVSGACL-CEAGFAGERCEARLCPEGLYG----IKCDKRCPCHLENTHSCHPMS 382
Query: 1945 GTCVCRPGVIGEKC-DRCAPDHWGLNTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVT 2002
G C C+PG G C + C+P + G C C+C CD G+C CA G
Sbjct: 383 GECACKPGWSGLYCNETCSPGFY----GEACQQICSC---QNGADCDSVTGKCTCAPGFK 435
Query: 2003 GKQCD-QCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCD-RCP 2057
G C C G + +C+ G +C+ G C C G G C RCP
Sbjct: 436 GIDCSTPCPLGTYGI------NCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCP 487
Score = 99 bits (238), Expect = 1e-19
Identities = 81/251 (32%), Positives = 96/251 (38%), Gaps = 43/251 (17%)
Query: 1817 CPMPYPSNNFALS--CDLSENGSLIS---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTG 1871
CP Y S + D +G I+ C C+PG+GG C G H G
Sbjct: 95 CPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGD---------HWG 145
Query: 1872 DYCKP-CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNCTA 1929
+C C C C+ I G C C G C + C G YG+ +
Sbjct: 146 PHCTSRCQCKNG------ALCNPITGAC-HCAAGFRGWRCEDRCEQGTYGNDCHQR---- 194
Query: 1930 CICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQC 1988
C C A CD TG C C PG G C D C P G C PC G C
Sbjct: 195 CQCQNG--ATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRC-PCQNG-----GVC 246
Query: 1989 DDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPG 2047
G+C C G G C Q C G + K+ C C+ G G ATGQC C PG
Sbjct: 247 HHVTGECSCPSGWMGTVCGQPCPEG--RFGKNCSQECQCHNG---GTCDAATGQCHCSPG 301
Query: 2048 VIGEKC-DRCP 2057
GE+C D CP
Sbjct: 302 YTGERCQDECP 312
Score = 95.5 bits (227), Expect = 3e-18
Identities = 80/257 (31%), Positives = 100/257 (38%), Gaps = 45/257 (17%)
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
R QC G+Y CVP D C A C C +GG C G +
Sbjct: 90 RKSQCCPGFYES----GEMCVPHCADKC--VHGRCIAPNTCQCEPGWGGTNCSSACDGDH 143
Query: 586 KYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDP 642
P C S C C G+ C+ G CHC + F G +C D C + Y + C C
Sbjct: 144 WGPHCTSRCQC----KNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ- 198
Query: 643 RGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGT 700
G T C V GE C+C G C D C P ++ P CEQ C C
Sbjct: 199 NGAT-----CDHV-TGE-CRCPPGYTGAFCEDLCPP-----GKHGP-QCEQRCPC----- 240
Query: 701 LNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD 759
+ G C+ +G+C C C Q C +G + + EC C GG+ CD
Sbjct: 241 -QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQ-----ECQCHNGGT----CD 290
Query: 760 KTTGQCHCHSRVEGRRC 776
TGQCHC G RC
Sbjct: 291 AATGQCHCSPGYTGERC 307
Score = 81.8 bits (193), Expect = 4e-14
Identities = 67/201 (33%), Positives = 81/201 (40%), Gaps = 27/201 (13%)
Query: 1316 PNETG-LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-C 1373
P TG LC E S N A C C G+ CN C C P IG CS C
Sbjct: 649 PGFTGALCNEVCPSGRFGKNC-AGICTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPC 703
Query: 1374 RTGYYGFPNC-RPCHCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCD-DC 1430
++G PNC C+C + A C +G C C G C + P F + C C
Sbjct: 704 PPAHWG-PNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGF---YGKDCALIC 759
Query: 1431 NCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVPGHYAFPDCYQ-CTCNRHGTTYD 1488
C N C+ SG+C CR GR C+ C G Y + C Q C C + T
Sbjct: 760 QCQ------NGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGY-GCRQICDCLNNST--- 809
Query: 1489 VCDQNTAQCYCKTNVRGQACD 1509
CD T CYC +G CD
Sbjct: 810 -CDHITGTCYCSPGWKGARCD 829
Score = 79.4 bits (187), Expect = 2e-13
Identities = 56/182 (30%), Positives = 77/182 (42%), Gaps = 19/182 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ GQC C P G C C G YG C C + C +G C+C GE
Sbjct: 289 CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGE 348
Query: 1410 NCD-RCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CV 1466
C+ R P + ++ CD C C+ + N C SG+CAC+ G C+ C
Sbjct: 349 RCEARLCPEGL-YGIK--CDKRCPCH----LENTHSCHPMSGECACKPGWSGLYCNETCS 401
Query: 1467 PGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT-CKEEYFNLQDDNPD 1524
PG Y C Q C+C ++G CD T +C C +G C T C + + +
Sbjct: 402 PGFYG-EACQQICSC-QNGAD---CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
Query: 1525 GC 1526
GC
Sbjct: 457 GC 458
Score = 79.0 bits (186), Expect = 3e-13
Identities = 52/165 (31%), Positives = 64/165 (38%), Gaps = 18/165 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
CN G C C G C C G YG + C C + A CD G C CP G
Sbjct: 160 CNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGA 219
Query: 1410 NC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVP 1467
C D C P ++ C C GV C +G+C+C G VC C
Sbjct: 220 FCEDLCPPGKHGPQCEQRCP---CQNGGV------CHHVTGECSCPSGWMGTVCGQPCPE 270
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTC 1511
G + +C C+ GT CD T QC+C G+ C D C
Sbjct: 271 GRFGKNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDEC 311
Score = 77.8 bits (183), Expect = 7e-13
Identities = 52/164 (31%), Positives = 68/164 (41%), Gaps = 20/164 (12%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEGENC-DRCK 1415
C C+P G CS+ G + P+C C C + A+C+ G C C G C DRC+
Sbjct: 124 CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCE 183
Query: 1416 PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPD 1474
T+ D + C C N C+ +G+C C G C D C PG + P
Sbjct: 184 QGTYGNDCHQRCQ---CQ------NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQ 233
Query: 1475 CYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYF 1516
C Q C C G VC T +C C + G C C E F
Sbjct: 234 CEQRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQPCPEGRF 273
Score = 77.4 bits (182), Expect = 9e-13
Identities = 56/187 (29%), Positives = 73/187 (39%), Gaps = 25/187 (13%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEG 1408
+C++ G+C C P G CS C G YG C C + A+C +G C C G
Sbjct: 420 DCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHG 479
Query: 1409 ENCD-RCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HC 1465
+C RC T+ F GC+ C C G C G C C RG C+ C
Sbjct: 480 VDCSIRCPSGTWGF----GCNLTCQCLNGGA------CNTLDGTCTCAPGWRGEKCELPC 529
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT-CKEEYFNLQDDNPD 1524
G Y +C C+ H D C T C C G CD+ C E + P+
Sbjct: 530 QDGTYGLNCAERCDCS-HA---DGCHPTTGHCRCLPGWSGVHCDSVCAEGRW-----GPN 580
Query: 1525 GCTKCFC 1531
C+C
Sbjct: 581 CSLPCYC 587
Score = 71.7 bits (168), Expect = 5e-11
Identities = 50/182 (27%), Positives = 70/182 (38%), Gaps = 21/182 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C+ G+C C P G C C G +G P C C C + +C G C CP G
Sbjct: 203 CDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 1409 ENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCV 1466
C + C F + + +C C+ G C+A +G+C C G C D C
Sbjct: 262 TVCGQPCPEGRFGKNCSQ---ECQCHNGGT------CDAATGQCHCSPGYTGERCQDECP 312
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT--CKEEYFNLQDDNPD 1524
G Y C C G Y V + C C+ G+ C+ C E + ++ D
Sbjct: 313 VGTYGVLCAETCQCVNGGKCYHV----SGACLCEAGFAGERCEARLCPEGLYGIKCDKRC 368
Query: 1525 GC 1526
C
Sbjct: 369 PC 370
Score = 68.9 bits (161), Expect = 3e-10
Identities = 56/202 (27%), Positives = 62/202 (30%), Gaps = 14/202 (6%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEGE 1409
CNT G C C P G C C+ G YG C C C G C C G
Sbjct: 507 CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGV 566
Query: 1410 NCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVPG 1468
+CD G NC+ N C D G C C RG C C PG
Sbjct: 567 HCDSV--------CAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPG 618
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYFNLQDDNPDGCT 1527
Y C Q TC + + C T C C G C + C F CT
Sbjct: 619 FYGH-RCSQ-TCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCT 676
Query: 1528 KCFCFGKTTRCSSSYYTWAAID 1549
R Y W D
Sbjct: 677 NNGTCNPIDRSCQCYPGWIGSD 698
Score = 62.5 bits (145), Expect = 3e-08
Identities = 47/166 (28%), Positives = 60/166 (36%), Gaps = 22/166 (13%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA--CRTGYYGF---PNCRPCHCPSTAICDD-NGMCICPK 1404
+C G C C+ G C A C G YG C PCH +T C +G C C
Sbjct: 331 KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC-PCHLENTHSCHPMSGECACKP 389
Query: 1405 NVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD 1463
G C + C P + Q+ C+C N C++ +GKC C +G C
Sbjct: 390 GWSGLYCNETCSPGFYGEACQQ---ICSCQ------NGADCDSVTGKCTCAPGFKGIDCS 440
Query: 1464 -HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C G Y +C C VC C CK G C
Sbjct: 441 TPCPLGTYGINCSSRCGCKNDA----VCSPVDGSCTCKAGWHGVDC 482
Score = 50.8 bits (116), Expect = 9e-05
Identities = 43/121 (35%), Positives = 55/121 (45%), Gaps = 23/121 (19%)
Query: 1735 ECQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC+C + GL C Q C G Y + CQC +D CD +G C C +G HC
Sbjct: 730 ECKCTPGWTGLYCTQRCPLGFY--GKDCALICQCQNGAD-CDHISGQC-TCRTGFMGRHC 785
Query: 1794 E-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
E C SG +G G + IC C NN +CD +C C PG+ GARC
Sbjct: 786 EQKCPSGTYG---YGCRQ---ICDC-----LNN--STCDHITG----TCYCSPGWKGARC 828
Query: 1853 E 1853
+
Sbjct: 829 D 829
>BC045172-1|AAH45172.2| 749|Homo sapiens LAMB4 protein protein.
Length = 749
Score = 173 bits (421), Expect = 1e-41
Identities = 84/218 (38%), Positives = 112/218 (51%), Gaps = 15/218 (6%)
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD-- 1939
NI+ DP SC + G+CL+C++NT GA C LC PG YG A+ ++ C C C G++
Sbjct: 1 NIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSAL-NQTCRRCSCHASGVSPME 59
Query: 1940 ---------CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCG-IASESTQCD 1989
CD TG C C P V G CDRCA +W L G GC C+C S+S+ CD
Sbjct: 60 CPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCD 119
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGV 2048
GQC C G GK+C +C ++ C C+CN + +C+ TG C C GV
Sbjct: 120 QLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGV 179
Query: 2049 IGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVEDLS 2086
G++CDRC R CL+C C D ++ LS
Sbjct: 180 SGQRCDRC-ARGHSQEFPTCLQCHLCFDQWDHTISSLS 216
Score = 152 bits (369), Expect = 2e-35
Identities = 70/205 (34%), Positives = 109/205 (53%), Gaps = 22/205 (10%)
Query: 409 NLNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYY----SPECKNCECNTVG------ 457
N++ T+ E C+ G C C +N G +C++C+ G+Y + C+ C C+ G
Sbjct: 1 NIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMEC 60
Query: 458 ---SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT---CKPCNCDTSGTEPSICDD 511
+ +CD +TG C C +G C++C GY+N C+ C+CD ++ S CD
Sbjct: 61 PPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQ 120
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLT 570
++GQC CK G+GG RC +C YY GR C+PC+C+ G+ C D G C C
Sbjct: 121 LTGQCPCKLGYGGKRCSECQENYYGDPPGR---CIPCDCNRAGTQKPICDPDTGMCRCRE 177
Query: 571 NFGGAQCDQCSPGY-YKYPDCLSCN 594
G +CD+C+ G+ ++P CL C+
Sbjct: 178 GVSGQRCDRCARGHSQEFPTCLQCH 202
Score = 142 bits (343), Expect = 3e-32
Identities = 64/188 (34%), Positives = 90/188 (47%), Gaps = 12/188 (6%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQ-----PCQCDPHFSTGNCEEESG 377
G+CL C HNT+G NC C+P +Y + C P +C P C+ +G
Sbjct: 15 GECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTG 74
Query: 378 RCECRPEFQPPDCSSCAYGYFDYP---NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGK 434
C C P C CA GY++ C+ C C+ ++ HC G CPCK Y GK
Sbjct: 75 ACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGK 134
Query: 435 SCEICEDGYYSP---ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY-YN 490
C C++ YY C C+CN G+ +CD TG C C+ SG+ C++C G+
Sbjct: 135 RCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQE 194
Query: 491 YPTCKPCN 498
+PTC C+
Sbjct: 195 FPTCLQCH 202
Score = 140 bits (340), Expect = 7e-32
Identities = 68/195 (34%), Positives = 96/195 (49%), Gaps = 20/195 (10%)
Query: 463 CDKLTGDCT-CKSKYSGRTCNQCQAGYYNYP---TCKPCNCDTSGTEPS---------IC 509
C ++TG+C C G C C+ G+Y TC+ C+C SG P +C
Sbjct: 10 CSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLC 69
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNC 568
D V+G C C G CD+C GY+ V GR C C+CDP S S+ C G+C C
Sbjct: 70 DPVTGACPCLPNVTGLACDRCADGYWNLVPGRG--CQSCDCDPRTSQSSHCDQLTGQCPC 127
Query: 569 LTNFGGAQCDQCSPGYYKYPD--CLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTC 625
+GG +C +C YY P C+ C+C+ +G+ CD D G+C C+ G +CD C
Sbjct: 128 KLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 187
Query: 626 -REQFYNYPACEECN 639
R +P C +C+
Sbjct: 188 ARGHSQEFPTCLQCH 202
Score = 119 bits (286), Expect = 2e-25
Identities = 68/211 (32%), Positives = 91/211 (43%), Gaps = 27/211 (12%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSACRTGYYGFP---NCRPCHCPSTAI-------------C 1394
C+ G+C C N G C C+ G+YG CR C C ++ + C
Sbjct: 10 CSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLC 69
Query: 1395 DD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCAC 1453
D G C C NV G CDRC +N RGC C+C+P C+ +G+C C
Sbjct: 70 DPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPR--TSQSSHCDQLTGQCPC 127
Query: 1454 RENVRGRVCDHCVPGHYAFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTC 1511
+ G+ C C +Y P C C CNR GT +CD +T C C+ V GQ CD C
Sbjct: 128 KLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 187
Query: 1512 KEEYFNLQDDNPDGCTKC-FCFGKTTRCSSS 1541
+ + P C +C CF + SS
Sbjct: 188 ARGH---SQEFPT-CLQCHLCFDQWDHTISS 214
Score = 118 bits (283), Expect = 5e-25
Identities = 69/199 (34%), Positives = 87/199 (43%), Gaps = 20/199 (10%)
Query: 1772 DQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICA---CPMPYPSNNFAL 1828
+ C TG CL C NT G +C+ C G++G A T R C A PM P A
Sbjct: 8 ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGAC 67
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP 1888
CD +C C P G C+ CA GY+ +L G C+ C+C +
Sbjct: 68 LCDPVTG----ACPCLPNVTGLACDRCADGYW------NLVPGRGCQSCDCDPRTS--QS 115
Query: 1889 GSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMAD--CDSTTGT 1946
CD + G C C G C+ C +YGD C C C+ G CD TG
Sbjct: 116 SHCDQLTGQC-PCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKPICDPDTGM 172
Query: 1947 CVCRPGVIGEKCDRCAPDH 1965
C CR GV G++CDRCA H
Sbjct: 173 CRCREGVSGQRCDRCARGH 191
Score = 109 bits (263), Expect = 1e-22
Identities = 65/194 (33%), Positives = 85/194 (43%), Gaps = 20/194 (10%)
Query: 609 GLC-HCKSNFDGAKCDTCREQFYNYP---ACEECNCDPRGVTA-----SFAGCGSVPAGE 659
G C C N GA C C+ Y C C+C GV+ C P
Sbjct: 15 GECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTG 74
Query: 660 LCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
C C V G C+ C YWNL GC+ C+C+ + +S C+ +GQC CK
Sbjct: 75 ACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPRTSQSS--HCDQLTGQCPCKLG 130
Query: 720 VGERQCDQCLDGFYRLQTNDVFG-CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G ++C +C + +Y D G C CDC+ G+ CD TG C C V G+RCD+
Sbjct: 131 YGGKRCSECQENYY----GDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR 186
Query: 779 PIRAH--YFPTLHQ 790
R H FPT Q
Sbjct: 187 CARGHSQEFPTCLQ 200
Score = 102 bits (245), Expect = 2e-20
Identities = 61/176 (34%), Positives = 76/176 (43%), Gaps = 23/176 (13%)
Query: 1321 LCREAMFSITSEYNSGARPCLCDFMGSTELECNTFG---------GQCPCKPNVIGRTCS 1371
LC+ + S N R C C G + +EC G G CPC PNV G C
Sbjct: 31 LCKPGHYG--SALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACD 88
Query: 1372 ACRTGYYGF---PNCRPCHC-PST---AICDD-NGMCICPKNVEGENCDRCKPYTFNFDV 1423
C GY+ C+ C C P T + CD G C C G+ C C+ + D
Sbjct: 89 RCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG-DP 147
Query: 1424 QRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH-YAFPDCYQC 1478
C C+CN G + C+ D+G C CRE V G+ CD C GH FP C QC
Sbjct: 148 PGRCIPCDCNRAGT--QKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQC 201
Score = 97.1 bits (231), Expect = 1e-18
Identities = 59/202 (29%), Positives = 84/202 (41%), Gaps = 24/202 (11%)
Query: 255 RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLD 314
RC HNT G C C G ++Q +C C+CH P L
Sbjct: 19 RCLHNTQGANCQLCKPGHYGS--ALNQ-----TCRRCSCHASGVSPMECPPGGGACLCDP 71
Query: 315 INGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFS-TGNCE 373
+ G C N G+ C++C Y+ R CQ C CDP S + +C+
Sbjct: 72 VTG-------ACPCLPNVTGLACDRCADGYWNLVPGRG-----CQSCDCDPRTSQSSHCD 119
Query: 374 EESGRCECRPEFQPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
+ +G+C C+ + CS C Y+ P C PC CN GT+ C P G+C C+
Sbjct: 120 QLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGV 179
Query: 432 AGKSCEICEDGYYS--PECKNC 451
+G+ C+ C G+ P C C
Sbjct: 180 SGQRCDRCARGHSQEFPTCLQC 201
Score = 83.0 bits (196), Expect = 2e-14
Identities = 44/110 (40%), Positives = 54/110 (49%), Gaps = 13/110 (11%)
Query: 1316 PNETGL----CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS 1371
PN TGL C + +++ G + C CD S C+ GQCPCK G+ CS
Sbjct: 80 PNVTGLACDRCADGYWNLVP--GRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS 137
Query: 1372 ACRTGYYGFP--NCRPCHC----PSTAICD-DNGMCICPKNVEGENCDRC 1414
C+ YYG P C PC C ICD D GMC C + V G+ CDRC
Sbjct: 138 ECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 187
Score = 78.6 bits (185), Expect = 4e-13
Identities = 63/210 (30%), Positives = 81/210 (38%), Gaps = 35/210 (16%)
Query: 1735 EC-QCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCN------------GHSDQCDVNTGI 1780
EC +C +G +C+ C GHY + C C C+ G + CD TG
Sbjct: 16 ECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGA 75
Query: 1781 CLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS 1840
C C N G C+ C GY + R C C C P + + CD
Sbjct: 76 C-PCLPNVTGLACDRCADGYW---NLVPGRGCQSCDCD---PRTSQSSHCDQLTG----Q 124
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C+ GYGG RC C YYG P C PC+C+ Q P CD G C +
Sbjct: 125 CPCKLGYGGKRCSECQENYYGDPPGR-------CIPCDCN-RAGTQKP-ICDPDTGMC-R 174
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTAC 1930
C +G C+ CA G + C C
Sbjct: 175 CREGVSGQRCDRCARGHSQEFPTCLQCHLC 204
Score = 54.8 bits (126), Expect = 6e-06
Identities = 44/179 (24%), Positives = 70/179 (39%), Gaps = 40/179 (22%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C G A C+P A C C N G C++C G+ W + C+
Sbjct: 60 CPPGGGACLCDPVTGA-------CPCLPNVTGLACDRCADGY----WNLVPG---RGCQS 105
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C+C T++ ++ ++ G+C C+ G C++C+ YY P G
Sbjct: 106 CDCDPRTSQSSHCDQLT---------------GQC-PCKLGYGGKRCSECQENYYGDPPG 149
Query: 350 KRWDELDVCQPCQCD-PHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF-DYPNCKPC 406
+ C PC C+ C+ ++G C CR C CA G+ ++P C C
Sbjct: 150 R-------CIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQC 201
Score = 44.0 bits (99), Expect = 0.010
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGY-YGFPNCRPCH 1387
PC C+ G+ + C+ G C C+ V G+ C C G+ FP C CH
Sbjct: 153 PCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCH 202
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 173 bits (420), Expect = 1e-41
Identities = 133/424 (31%), Positives = 172/424 (40%), Gaps = 66/424 (15%)
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKP-CTCNLNGT 413
D Q CQC + C+ +G C C P + C C G P C+ C C NG
Sbjct: 190 DCHQRCQCQ---NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQ-NGG 244
Query: 414 EGEHCTPTDGLCPCKYNYAGKSC-EICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCT 471
H T G C C + G C + C +G + C + C+C+ G+ CD TG C
Sbjct: 245 VCHHVT---GECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGT----CDAATGQCH 297
Query: 472 CKSKYSGRTC-NQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQC 530
C Y+G C ++C G Y + C C G C VSG C+C+AGF G RC+
Sbjct: 298 CSPGYTGERCQDECPVGTYGVLCAETCQCVNGGK----CYHVSGACLCEAGFAGERCEAR 353
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPD 589
L + + +++C PC+ + T S G+C C + G C++ CSPG+Y
Sbjct: 354 LCPEGLYGIKCDKRC-PCHLENTHSCH---PMSGECACKPGWSGLYCNETCSPGFYGEAC 409
Query: 590 CLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTA 647
C+C G+ CD G C C F G C T C Y C C V +
Sbjct: 410 QQICSC----QNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCS 465
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLG 705
P C CK G C+ C W FGC C C LN G
Sbjct: 466 --------PVDGSCTCKAGWHGVDCSIRCPSGTWG------FGCNLTCQC-----LNG-G 505
Query: 706 ACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTG 763
ACNT G C C +C+ C DG Y L C E CDC S + C TTG
Sbjct: 506 ACNTLDGTCTCAPGWRGEKCELPCQDGTYGL------NCAERCDC----SHADGCHPTTG 555
Query: 764 QCHC 767
C C
Sbjct: 556 HCRC 559
Score = 157 bits (380), Expect = 9e-37
Identities = 137/478 (28%), Positives = 188/478 (39%), Gaps = 76/478 (15%)
Query: 315 INGRYEGGGKCLNCQHNTEGINCNK-CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
++GR C C+ G NC+ C ++ P+ CQC + C
Sbjct: 114 VHGRCIAPNTC-QCEPGWGGTNCSSACDGDHWGPH--------CTSRCQCK---NGALCN 161
Query: 374 EESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
+G C C F+ C C G + + C C NG +H T G C C Y
Sbjct: 162 PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ-NGATCDHVT---GECRCPPGYT 217
Query: 433 GKSCE-ICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYY 489
G CE +C G + P+C+ C C G VC +TG+C+C S + G C Q C G +
Sbjct: 218 GAFCEDLCPPGKHGPQCEQRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQPCPEGRF 273
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPC 548
+ C C GT CD +GQC C G+ G RC D+C G Y + QCV
Sbjct: 274 GKNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCV-- 327
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLSCNCDVSGSIGSTCD 606
G S G C C F G +C+ C G Y C C + + +C
Sbjct: 328 ----NGGKCYHVS--GACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENT--HSCH 379
Query: 607 D-NGLCHCKSNFDGAKC-DTCREQFYNYPACEE-CNCDPRGVTASFAGCGSVPAGELCQC 663
+G C CK + G C +TC FY AC++ C+C + A C SV G+ C C
Sbjct: 380 PMSGECACKPGWSGLYCNETCSPGFYG-EACQQICSCQ------NGADCDSV-TGK-CTC 430
Query: 664 KDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
+G C+ PL G NC+ + C+ G C CK
Sbjct: 431 APGFKGIDCSTPCPL----------GTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
Query: 724 QCD-QCLDGFYRLQTNDVFGCT-ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C +C G + FGC C C GG+ C+ G C C G +C+ P
Sbjct: 481 DCSIRCPSGTWG------FGCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELP 528
Score = 149 bits (362), Expect = 1e-34
Identities = 122/433 (28%), Positives = 175/433 (40%), Gaps = 65/433 (15%)
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKP-CTCNLNGTE 414
++C P C G C + C+C P + +CSS G P+C C C
Sbjct: 103 EMCVP-HCADKCVHGRCIAPN-TCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCK----N 156
Query: 415 GEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTC 472
G C P G C C + G CE CE G Y +C + C+C CD +TG+C C
Sbjct: 157 GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQN----GATCDHVTGECRC 212
Query: 473 KSKYSGRTCNQ-CQAGYYNYPTCKP-CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ- 529
Y+G C C G + P C+ C C G +C V+G+C C +G+ G C Q
Sbjct: 213 PPGYTGAFCEDLCPPGKHG-PQCEQRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQP 267
Query: 530 CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC-DQCSPGYYKYP 588
C G + + +E C C G T +A G+C+C + G +C D+C G Y
Sbjct: 268 CPEGRFGKNCSQE-----CQCHNGG---TCDAATGQCHCSPGYTGERCQDECPVGTYGVL 319
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEECNCDPRGVT 646
+C C V+G G +G C C++ F G +C+ C E Y + C C
Sbjct: 320 CAETCQC-VNG--GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTH 376
Query: 647 ASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGTLNSL 704
+ C + +GE C CK G CN+ C P ++ C+Q C+C
Sbjct: 377 S----CHPM-SGE-CACKPGWSGLYCNETCSPGFYG------EACQQICSCQNGAD---- 420
Query: 705 GACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
C++ +G+C C C C G Y + + GC D C G
Sbjct: 421 --CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN---------DAVCSPVDG 469
Query: 764 QCHCHSRVEGRRC 776
C C + G C
Sbjct: 470 SCTCKAGWHGVDC 482
Score = 134 bits (323), Expect = 8e-30
Identities = 109/399 (27%), Positives = 160/399 (40%), Gaps = 58/399 (14%)
Query: 391 SSCAYGYFDYPN-CKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPEC 448
S C G+++ C P C G P C C+ + G +C C+ ++ P C
Sbjct: 92 SQCCPGFYESGEMCVP-HCADKCVHGRCIAPNT--CQCEPGWGGTNCSSACDGDHWGPHC 148
Query: 449 KN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKPCNCDTSGTEP 506
+ C+C +C+ +TG C C + + G C ++C+ G Y + C C T
Sbjct: 149 TSRCQCKN----GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGAT-- 202
Query: 507 SICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK 565
CD V+G+C C G+ G C D C G + E++C PC + G+
Sbjct: 203 --CDHVTGECRCPPGYTGAFCEDLCPPGKHGPQC--EQRC-PCQ-----NGGVCHHVTGE 252
Query: 566 CNCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKC- 622
C+C + + G C Q C G + C C G TCD G CHC + G +C
Sbjct: 253 CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGG----TCDAATGQCHCSPGYTGERCQ 308
Query: 623 DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL 682
D C Y E C C G +G AG +R + R+C + LY
Sbjct: 309 DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGF---AGERCEARLCPE--GLYG-- 361
Query: 683 QEYNPFGCEQ-CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDV 740
C++ C C+L T +C+ SG+C CK C++ C GFY +
Sbjct: 362 -----IKCDKRCPCHLENT----HSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQI 412
Query: 741 FGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C C G +CD TG+C C +G C P
Sbjct: 413 -----CSCQNGA----DCDSVTGKCTCAPGFKGIDCSTP 442
Score = 133 bits (322), Expect = 1e-29
Identities = 110/329 (33%), Positives = 143/329 (43%), Gaps = 63/329 (19%)
Query: 1735 ECQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC CP + G C Q C EG R CQC+ + CD TG C +C+ G+ C
Sbjct: 252 ECSCPSGWMGTVCGQPCPEG--RFGKNCSQECQCH-NGGTCDAATGQC-HCSPGYTGERC 307
Query: 1794 EF-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G +G T C C N +S +C C+ G+ G RC
Sbjct: 308 QDECPVGTYGVLCAET------CQCV------NGGKCYHVSG-----ACLCEAGFAGERC 350
Query: 1853 E--YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
E C G YGI D K C C + ++ SC ++G+C C +G C
Sbjct: 351 EARLCPEGLYGIKCD---------KRCPC----HLENTHSCHPMSGECA-CKPGWSGLYC 396
Query: 1911 N-LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
N C+PGFYG+A C IC ADCDS TG C C PG G C P L
Sbjct: 397 NETCSPGFYGEA-----CQQ-ICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCP----LG 446
Query: 1970 T-GLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCD-HCNC 2026
T G+ C+ CG +++ C +G C C G G C +C +G W + GC+ C C
Sbjct: 447 TYGINCS-SRCGCKNDAV-CSPVDGSCTCKAGWHGVDCSIRCPSGTWGF---GCNLTCQC 501
Query: 2027 NTGYSVGFMCNA-TGQCECLPGVIGEKCD 2054
G + CN G C C PG GEKC+
Sbjct: 502 LNGGA----CNTLDGTCTCAPGWRGEKCE 526
Score = 103 bits (247), Expect = 1e-20
Identities = 102/358 (28%), Positives = 128/358 (35%), Gaps = 73/358 (20%)
Query: 1736 CQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C +RG CE +C +G Y + CQC + CD TG C C G CE
Sbjct: 167 CHCAAGFRGWRCEDRCEQGTY--GNDCHQRCQCQ-NGATCDHVTGEC-RCPPGYTGAFCE 222
Query: 1795 -FCMSGYHG------------------DATVGTPRDCLICACPMPYPSNNFALSCDLS-- 1833
C G HG P + C P P F +C
Sbjct: 223 DLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQ 282
Query: 1834 -ENGSLI-----SCNCQPGYGGARC-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
NG C+C PGY G RC + C G YG+ + C C +N
Sbjct: 283 CHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVL---------CAETCQC---VN-- 328
Query: 1887 DPGSCDSINGDCLKCVNNTAGAAC--NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT 1944
G C ++G CL C AG C LC G YG K C C C +
Sbjct: 329 -GGKCYHVSGACL-CEAGFAGERCEARLCPEGLYG----IKCDKRCPCHLENTHSCHPMS 382
Query: 1945 GTCVCRPGVIGEKC-DRCAPDHWGLNTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVT 2002
G C C+PG G C + C+P + G C C+C CD G+C CA G
Sbjct: 383 GECACKPGWSGLYCNETCSPGFY----GEACQQICSC---QNGADCDSVTGKCTCAPGFK 435
Query: 2003 GKQCD-QCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCD-RCP 2057
G C C G + +C+ G +C+ G C C G G C RCP
Sbjct: 436 GIDCSTPCPLGTYGI------NCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCP 487
Score = 99 bits (238), Expect = 1e-19
Identities = 81/251 (32%), Positives = 96/251 (38%), Gaps = 43/251 (17%)
Query: 1817 CPMPYPSNNFALS--CDLSENGSLIS---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTG 1871
CP Y S + D +G I+ C C+PG+GG C G H G
Sbjct: 95 CPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGD---------HWG 145
Query: 1872 DYCKP-CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNCTA 1929
+C C C C+ I G C C G C + C G YG+ +
Sbjct: 146 PHCTSRCQCKNG------ALCNPITGAC-HCAAGFRGWRCEDRCEQGTYGNDCHQR---- 194
Query: 1930 CICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQC 1988
C C A CD TG C C PG G C D C P G C PC G C
Sbjct: 195 CQCQNG--ATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRC-PCQNG-----GVC 246
Query: 1989 DDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPG 2047
G+C C G G C Q C G + K+ C C+ G G ATGQC C PG
Sbjct: 247 HHVTGECSCPSGWMGTVCGQPCPEG--RFGKNCSQECQCHNG---GTCDAATGQCHCSPG 301
Query: 2048 VIGEKC-DRCP 2057
GE+C D CP
Sbjct: 302 YTGERCQDECP 312
Score = 95.5 bits (227), Expect = 3e-18
Identities = 80/257 (31%), Positives = 99/257 (38%), Gaps = 45/257 (17%)
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
R QC G+Y CVP D C A C C +GG C G +
Sbjct: 90 RKSQCCPGFYES----GEMCVPHCADKC--VHGRCIAPNTCQCEPGWGGTNCSSACDGDH 143
Query: 586 KYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDP 642
P C S C C G+ C+ G CHC + F G +C D C + Y + C C
Sbjct: 144 WGPHCTSRCQC----KNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ- 198
Query: 643 RGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGT 700
G T C V GE C+C G C D C P ++ P CEQ C C G
Sbjct: 199 NGAT-----CDHV-TGE-CRCPPGYTGAFCEDLCPP-----GKHGP-QCEQRCPCQNGGV 245
Query: 701 LNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD 759
C+ +G+C C C Q C +G + + EC C GG+ CD
Sbjct: 246 ------CHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQ-----ECQCHNGGT----CD 290
Query: 760 KTTGQCHCHSRVEGRRC 776
TGQCHC G RC
Sbjct: 291 AATGQCHCSPGYTGERC 307
Score = 79.4 bits (187), Expect = 2e-13
Identities = 56/182 (30%), Positives = 77/182 (42%), Gaps = 19/182 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ GQC C P G C C G YG C C + C +G C+C GE
Sbjct: 289 CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGE 348
Query: 1410 NCD-RCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CV 1466
C+ R P + ++ CD C C+ + N C SG+CAC+ G C+ C
Sbjct: 349 RCEARLCPEGL-YGIK--CDKRCPCH----LENTHSCHPMSGECACKPGWSGLYCNETCS 401
Query: 1467 PGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT-CKEEYFNLQDDNPD 1524
PG Y C Q C+C ++G CD T +C C +G C T C + + +
Sbjct: 402 PGFYG-EACQQICSC-QNGAD---CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
Query: 1525 GC 1526
GC
Sbjct: 457 GC 458
Score = 79.0 bits (186), Expect = 3e-13
Identities = 52/165 (31%), Positives = 64/165 (38%), Gaps = 18/165 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
CN G C C G C C G YG + C C + A CD G C CP G
Sbjct: 160 CNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGA 219
Query: 1410 NC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVP 1467
C D C P ++ C C GV C +G+C+C G VC C
Sbjct: 220 FCEDLCPPGKHGPQCEQRCP---CQNGGV------CHHVTGECSCPSGWMGTVCGQPCPE 270
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTC 1511
G + +C C+ GT CD T QC+C G+ C D C
Sbjct: 271 GRFGKNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDEC 311
Score = 77.8 bits (183), Expect = 7e-13
Identities = 52/164 (31%), Positives = 68/164 (41%), Gaps = 20/164 (12%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEGENC-DRCK 1415
C C+P G CS+ G + P+C C C + A+C+ G C C G C DRC+
Sbjct: 124 CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCE 183
Query: 1416 PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPD 1474
T+ D + C C N C+ +G+C C G C D C PG + P
Sbjct: 184 QGTYGNDCHQRCQ---CQ------NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQ 233
Query: 1475 CYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYF 1516
C Q C C G VC T +C C + G C C E F
Sbjct: 234 CEQRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQPCPEGRF 273
Score = 71.7 bits (168), Expect = 5e-11
Identities = 50/182 (27%), Positives = 70/182 (38%), Gaps = 21/182 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C+ G+C C P G C C G +G P C C C + +C G C CP G
Sbjct: 203 CDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 1409 ENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCV 1466
C + C F + + +C C+ G C+A +G+C C G C D C
Sbjct: 262 TVCGQPCPEGRFGKNCSQ---ECQCHNGGT------CDAATGQCHCSPGYTGERCQDECP 312
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT--CKEEYFNLQDDNPD 1524
G Y C C G Y V + C C+ G+ C+ C E + ++ D
Sbjct: 313 VGTYGVLCAETCQCVNGGKCYHV----SGACLCEAGFAGERCEARLCPEGLYGIKCDKRC 368
Query: 1525 GC 1526
C
Sbjct: 369 PC 370
Score = 71.7 bits (168), Expect = 5e-11
Identities = 48/154 (31%), Positives = 61/154 (39%), Gaps = 19/154 (12%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEG 1408
+C++ G+C C P G CS C G YG C C + A+C +G C C G
Sbjct: 420 DCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHG 479
Query: 1409 ENCD-RCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HC 1465
+C RC T+ F GC+ C C G C G C C RG C+ C
Sbjct: 480 VDCSIRCPSGTWGF----GCNLTCQCLNGGA------CNTLDGTCTCAPGWRGEKCELPC 529
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
G Y +C C+ H D C T C C
Sbjct: 530 QDGTYGLNCAERCDCS-HA---DGCHPTTGHCRC 559
Score = 69.7 bits (163), Expect = 2e-10
Identities = 71/243 (29%), Positives = 95/243 (39%), Gaps = 39/243 (16%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDH 1792
C C + G CE C EG Y + PC N HS C +G C C G +
Sbjct: 339 CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS--CHPMSGECA-CKPGWSGLY 395
Query: 1793 C-EFCMSGYHGDA-----TVGTPRDC------LICA-------CPMPYPSNNFALSCDLS 1833
C E C G++G+A + DC CA C P P + ++C S
Sbjct: 396 CNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCS-S 454
Query: 1834 ENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G C P G C+ AG++G+ +G + CN + + G+C++
Sbjct: 455 RCGCKNDAVCSPVDGSCTCK---AGWHGVDCSIRCPSGTWGFGCNLTCQC--LNGGACNT 509
Query: 1894 INGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
++G C C G C L C G YG NC A CD C TTG C C PG
Sbjct: 510 LDGTCT-CAPGWRGEKCELPCQDGTYG-----LNC-AERCDCSHADGCHPTTGHCRCLPG 562
Query: 1953 VIG 1955
G
Sbjct: 563 WSG 565
Score = 62.5 bits (145), Expect = 3e-08
Identities = 47/166 (28%), Positives = 60/166 (36%), Gaps = 22/166 (13%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA--CRTGYYGF---PNCRPCHCPSTAICDD-NGMCICPK 1404
+C G C C+ G C A C G YG C PCH +T C +G C C
Sbjct: 331 KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC-PCHLENTHSCHPMSGECACKP 389
Query: 1405 NVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD 1463
G C + C P + Q+ C+C N C++ +GKC C +G C
Sbjct: 390 GWSGLYCNETCSPGFYGEACQQ---ICSCQ------NGADCDSVTGKCTCAPGFKGIDCS 440
Query: 1464 -HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C G Y +C C VC C CK G C
Sbjct: 441 TPCPLGTYGINCSSRCGCKNDA----VCSPVDGSCTCKAGWHGVDC 482
Score = 37.5 bits (83), Expect = 0.90
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 8/74 (10%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
CQC + G C G C C P ++ C C G + + C C+ + C
Sbjct: 499 CQC---LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCS----HADGCH 551
Query: 420 PTDGLCPCKYNYAG 433
PT G C C ++G
Sbjct: 552 PTTGHCRCLPGWSG 565
>AB011105-1|BAA25459.1| 1645|Homo sapiens KIAA0533 protein protein.
Length = 1645
Score = 172 bits (418), Expect = 2e-41
Identities = 216/994 (21%), Positives = 387/994 (38%), Gaps = 78/994 (7%)
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
CDRC H+G N GC PC CG A+E ++C +GQC C G G QC +CA G+W
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 60
Query: 2018 KDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEG--------C 2068
+ GC C C G C+ TG+C C PG+ GE+CD C ++ +P G C
Sbjct: 61 EQGCRRCQCPGG-----RCDPHTGRCNCPPGLSGERCDTCSQQH-QVPVPGGPVGHSIHC 114
Query: 2069 LECDSCTDALIFSVEDLSALLA---NETMDFKDKADSFFTTQRLN--YISNQTELLRPKV 2123
CD C L+ +E ALL + + ++ RLN Q++L P
Sbjct: 115 EVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLG 174
Query: 2124 AQLKTVDIGEVTSSIKT-LETSAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRE 2182
+ +T EV T L A+ L A + + ++ A+ LAA+R
Sbjct: 175 PRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRA 234
Query: 2183 SAREATEVVKHVADLATGLELSQQPKVDS---ALTEARQIRDDIADKDLVPKKQQAEAVF 2239
R +E++ L GL + P + L E ++ ++ +DL + AEA
Sbjct: 235 VDRTLSELMSQTGHL--GLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAEL 292
Query: 2240 LNTTTQIERMNFFVQPVNEQAKASSHRPDLKFESLVNATRELKDKLDDMLEYTDLAQHTA 2299
+ R+ + + E+ +A + + + +L++ L+ ++ T
Sbjct: 293 AAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDAT------- 345
Query: 2300 HTAEELNTKN--RLSKFGNKVNSVTKLNTAAMGDLIDAAYDIGNATYNNMXXXXXXXXXX 2357
A+ELN++N RL + + +++ N A + + AA D + + +
Sbjct: 346 REAQELNSRNQERLEEALQRKQELSRDN-ATLQATLHAARDTLASVFRLLHSLDQAKEEL 404
Query: 2358 XXXXXXXXXXXXXXXXXXXXTGELPQFEHLTSEATHHATMLRRRADSLRELAERENNNSR 2417
L A HA L + A +L + N +
Sbjct: 405 ERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRL 464
Query: 2418 TQHXXXXXXXXXXXXQEINXXXXXXXXXXXXXXNVTKLNRILDERVRPARERSSSLLADA 2477
TQ Q + + T + V +R+ LLA++
Sbjct: 465 TQRAIEASNAYSRILQAVQAAEDAAGQALQQADH-TWATVVRQGLV----DRAQQLLANS 519
Query: 2478 TKAQHAV---DQKLLPNLTATEEVLRKIRDHLSRADDDDNAIQXXXXXXXXXXXXXXXN- 2533
T + A+ Q+L A + ++RD ++ D + IQ
Sbjct: 520 TALEEAMLQEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKI 579
Query: 2534 -KADRVNATI-GTTFSVMSHLGPELATSKDWAQTLPKLADEGQKMTSNVESHLKNINDME 2591
A V A T V S L + W L GQ + V +++ +E
Sbjct: 580 AHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGL--RGQDLGQAVLDAGHSVSTLE 637
Query: 2592 PQISSSYHTVK-MXXXXXXXXXXXXXXKLQKLKDLVEQARTVANRIQVGVTFDRWSTLQP 2650
+ + + + ++++L+ QAR A++++V + F+ S +Q
Sbjct: 638 KTLPQLLAKLSILENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQL 697
Query: 2651 RLPDTVDEMSTSTHVSAYFRTKE-------KDGFILYLGNPKGTMLRRTKSDDYMVIGIQ 2703
R P + +++ T + Y + E +D F++Y+G+ R + DYM + ++
Sbjct: 698 RTPRDLADLAAYTALKFYLQGPEPEPGQGTEDRFVMYMGS-------RQATGDYMGVSLR 750
Query: 2704 NGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDT 2763
+ + V +G++ PA +SID+ + + ++ V +DR + +S+ +T
Sbjct: 751 DKKVHWVYQLGEAG-----PAVLSIDEDIGE-QFAAVSLDRTLQFGHMSVTVERQMIQET 804
Query: 2764 IHSKEADLPGHHTIFNLDKEKSKLYVGGVPSD-AKLQGISFPAFEGQIEELMIGDTPVGL 2822
+ PG + NL + YVGG PS + FP + G IE + + V L
Sbjct: 805 --KGDTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSL 862
Query: 2823 WNFVSANKLKGARQRDKLISSQSG----PQEYRFDGRGYATMAGRGYLTPQSNQVLLFFR 2878
+NF +L A R S +G DG G+A ++ ++ + + R
Sbjct: 863 YNFERTFQLDTAVDRPCARSKSTGDPWLTDGSYLDGTGFARISFDSQIS-TTKRFEQELR 921
Query: 2879 TYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLG 2912
+ +G+++ + + F L +Q+G + L G
Sbjct: 922 LVSYSGVLFFLKQQSQFLCLAVQEGSLVLLYDFG 955
Score = 81.0 bits (191), Expect = 7e-14
Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 10/107 (9%)
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHY 1470
CDRC+ F F+ GC C C P +C SG+C CR G C C PG++
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGP---AAEGSECHPQSGQCHCRPGTMGPQCRECAPGYW 57
Query: 1471 AFPD--CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
P+ C +C C CD +T +C C + G+ CDTC +++
Sbjct: 58 GLPEQGCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTCSQQH 99
Score = 80.2 bits (189), Expect = 1e-13
Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
C+ C G +G C C C ++C +G C CRPG +G +C CAP +WGL
Sbjct: 1 CDRCQEGHFGFNGCG-GCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGL 59
Query: 1969 NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
GC C C +CD G+C C G++G++CD C+
Sbjct: 60 -PEQGCRRCQC----PGGRCDPHTGRCNCPPGLSGERCDTCS 96
Score = 80.2 bits (189), Expect = 1e-13
Identities = 36/95 (37%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFP 1381
C+E F G RPC C + EC+ GQC C+P +G C C GY+G P
Sbjct: 4 CQEGHFGFNG--CGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 60
Query: 1382 --NCRPCHCPSTAICDDNGMCICPKNVEGENCDRC 1414
CR C CP G C CP + GE CD C
Sbjct: 61 EQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTC 95
Score = 75.4 bits (177), Expect = 4e-12
Identities = 32/91 (35%), Positives = 41/91 (45%), Gaps = 7/91 (7%)
Query: 358 CQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP--NCKPCTCNLNGTEG 415
C+PC C P C +SG+C CRP P C CA GY+ P C+ C C G
Sbjct: 17 CRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-----PG 71
Query: 416 EHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
C P G C C +G+ C+ C + P
Sbjct: 72 GRCDPHTGRCNCPPGLSGERCDTCSQQHQVP 102
Score = 74.9 bits (176), Expect = 5e-12
Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 10/105 (9%)
Query: 527 CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYK 586
CD+C G++ C PC C P S G+C+C G QC +C+PGY+
Sbjct: 1 CDRCQEGHFG--FNGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWG 58
Query: 587 YPD--CLSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQ 628
P+ C C C G CD + G C+C G +CDTC +Q
Sbjct: 59 LPEQGCRRCQCP-----GGRCDPHTGRCNCPPGLSGERCDTCSQQ 98
Score = 73.3 bits (172), Expect = 1e-11
Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 11/104 (10%)
Query: 481 CNQCQAGYYNYPTC---KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQ 537
C++CQ G++ + C +PC C + E S C SGQC C+ G GP+C +C GY+
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAA-EGSECHPQSGQCHCRPGTMGPQCRECAPGYWGL 59
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
E+ C C C P G G+CNC G +CD CS
Sbjct: 60 ---PEQGCRRCQC-PGGRCDPH---TGRCNCPPGLSGERCDTCS 96
Score = 70.5 bits (165), Expect = 1e-10
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 17/115 (14%)
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAAC 1910
C+ C G++G + C+PC C P GS C +G C C T G C
Sbjct: 1 CDRCQEGHFGF------NGCGGCRPCACG----PAAEGSECHPQSGQC-HCRPGTMGPQC 49
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDH 1965
CAPG++G + + C C C CD TG C C PG+ GE+CD C+ H
Sbjct: 50 RECAPGYWG--LPEQGCRRCQCPG---GRCDPHTGRCNCPPGLSGERCDTCSQQH 99
Score = 68.9 bits (161), Expect = 3e-10
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 390 CSSCAYGYFDYPNC---KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS- 445
C C G+F + C +PC C EG C P G C C+ G C C GY+
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGL 59
Query: 446 PE--CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
PE C+ C+C CD TG C C SG C+ C
Sbjct: 60 PEQGCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTC 95
Score = 66.1 bits (154), Expect = 2e-09
Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 12/111 (10%)
Query: 436 CEICEDGYYSPE----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY 491
C+ C++G++ C+ C C S C +G C C+ G C +C GY+
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAAEGSE-CHPQSGQCHCRPGTMGPQCRECAPGYWGL 59
Query: 492 PT--CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLG 540
P C+ C C CD +G+C C G G RCD C + + V G
Sbjct: 60 PEQGCRRCQCPGGR-----CDPHTGRCNCPPGLSGERCDTCSQQHQVPVPG 105
Score = 63.7 bits (148), Expect = 1e-08
Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 11/98 (11%)
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
GC C C A + C+ +SGQC C+ QC +C G++ L GC C C
Sbjct: 16 GCRPCACGPAAEGSE---CHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ---GCRRCQC 69
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFP 786
GG CD TG+C+C + G RCD + H P
Sbjct: 70 P-GG----RCDPHTGRCNCPPGLSGERCDTCSQQHQVP 102
Score = 62.9 bits (146), Expect = 2e-08
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 12/107 (11%)
Query: 622 CDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWN 681
CD C+E + + C C G A + C P C C+ G C +C P YW
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAAEGSECH--PQSGQCHCRPGTMGPQCRECAPGYWG 58
Query: 682 LQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQC 728
L E GC +C C G G C+ +G+C C + +CD C
Sbjct: 59 LPEQ---GCRRCQC--PG-----GRCDPHTGRCNCPPGLSGERCDTC 95
Score = 61.3 bits (142), Expect = 6e-08
Identities = 38/113 (33%), Positives = 47/113 (41%), Gaps = 20/113 (17%)
Query: 1747 CEQCAEGHYRLPS-GFCVPCQCN--GHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGD 1803
C++C EGH+ G C PC C +C +G C +C T+G C C GY G
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAAEGSECHPQSGQC-HCRPGTMGPQCRECAPGYWGL 59
Query: 1804 ATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCA 1856
G C C CP CD G CNC PG G RC+ C+
Sbjct: 60 PEQG----CRRCQCP--------GGRCD-PHTG---RCNCPPGLSGERCDTCS 96
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 18/218 (8%)
Query: 3456 FMGCLKGLLMNGQQVTRIGNAVNALRCV-DNIEDGVYFEASNNTHSNYLKLLENFKVGDE 3514
F GC+K L ++G+ + C+ +E G++F S + L +
Sbjct: 1437 FSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGV----ITLDLPGATLPD 1492
Query: 3515 VSISMEVRPRNTTGLLLSVHGKKD--YMVLELLDSEVVANVENGNGPFRATYKLSNKHYL 3572
V + +EVRP TGL+ + + Y+ L++ + +V+ ++G G F + ++ L
Sbjct: 1493 VGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTS--VTRPSVL 1550
Query: 3573 CDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAY--TSTDTHSALYIGGHERPIHKVRGVH 3630
CDG WH++ D S +G + + LY+GG P+ V+
Sbjct: 1551 CDGQWHRLAVMKSGNVLRLEVDAQ-SNHTVGPLLAAAAGAPAPLYLGGLPEPM-AVQPWP 1608
Query: 3631 SRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGV--CP 3666
+ GC+R + V +PV + S GA VG CP
Sbjct: 1609 P--AYCGCMRRLAVNRSPVAMTRSVEVHGA-VGASGCP 1643
Score = 59.3 bits (137), Expect = 3e-07
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 15/107 (14%)
Query: 1370 CSACRTGYYGFPNC---RPCHCPSTAICDD----NGMCICPKNVEGENCDRCKPYTFNFD 1422
C C+ G++GF C RPC C A + +G C C G C C P +
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 60
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
++GC C C P G +C+ +G+C C + G CD C H
Sbjct: 61 -EQGCRRCQC-PGG------RCDPHTGRCNCPPGLSGERCDTCSQQH 99
Score = 55.6 bits (128), Expect = 3e-06
Identities = 28/75 (37%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C C G C +CA G++ LP C CQC G +CD +TG C NC G+ C+
Sbjct: 37 QCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPG--GRCDPHTGRC-NCPPGLSGERCD 93
Query: 1795 FCMSGYHGDATVGTP 1809
C S H G P
Sbjct: 94 TC-SQQHQVPVPGGP 107
Score = 53.6 bits (123), Expect = 1e-05
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 26/122 (21%)
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C+ C G+ G G C CAC P + C ++G C+C+PG G +C
Sbjct: 1 CDRCQEGHFGFNGCG---GCRPCACG-PAAEGS---ECH-PQSGQ---CHCRPGTMGPQC 49
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
CA GY+G+PE C+ C C G G CD G C C +G C+
Sbjct: 50 RECAPGYWGLPEQG-------CRRCQCPG-------GRCDPHTGRC-NCPPGLSGERCDT 94
Query: 1913 CA 1914
C+
Sbjct: 95 CS 96
Score = 50.4 bits (115), Expect = 1e-04
Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 18/127 (14%)
Query: 577 CDQCSPGYYKYPDCLSCNCDVSGSI--GSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYP 633
CD+C G++ + C C G GS C +G CHC+ G +C C ++ P
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 60
Query: 634 --ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-- 689
C C C P G C P C C + G C+ C + P G
Sbjct: 61 EQGCRRCQC-PGG------RCD--PHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHS 111
Query: 690 --CEQCN 694
CE C+
Sbjct: 112 IHCEVCD 118
Score = 49.2 bits (112), Expect = 3e-04
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 1462 CDHCVPGHYAFPDCYQCTCNRHGTTYD--VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQ 1519
CD C GH+ F C C G + C + QC+C+ G C C Y+ L
Sbjct: 1 CDRCQEGHFGFNGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 60
Query: 1520 DDNPDGCTKCFCFG 1533
+ GC +C C G
Sbjct: 61 E---QGCRRCQCPG 71
Score = 42.3 bits (95), Expect = 0.032
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 11/72 (15%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECR 382
G+C +C+ T G C +C P Y+ + C+ CQC G C+ +GRC C
Sbjct: 36 GQC-HCRPGTMGPQCRECAPGYWGLPEQG------CRRCQC----PGGRCDPHTGRCNCP 84
Query: 383 PEFQPPDCSSCA 394
P C +C+
Sbjct: 85 PGLSGERCDTCS 96
Score = 41.1 bits (92), Expect = 0.073
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 10/81 (12%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRI-SQNWDRFSCE 289
C C A+ E +G C C+ T GPQC +C G+ W + Q R C
Sbjct: 20 CACGPAAEGSECHPQSGQ-----CHCRPGTMGPQCRECAPGY----WGLPEQGCRRCQCP 70
Query: 290 PCNCHNHTTECTYDPEIDEKR 310
C HT C P + +R
Sbjct: 71 GGRCDPHTGRCNCPPGLSGER 91
Score = 40.7 bits (91), Expect = 0.097
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 15/178 (8%)
Query: 3488 DGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLL---SVHGKKDYMVLEL 3544
D F S ++H ++ +L + + S+SM V PR++ GLLL + + L L
Sbjct: 1289 DSYQFGGSLSSHLEFVGILARHR--NWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFL 1346
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDG--HFSKPGI 3602
+ VA +E RA + ++ G WHK+ DG +S+ G
Sbjct: 1347 SNGHFVAQMEGLGTRLRAQSRQRSR----PGRWHKVSVRWEKNRILLVTDGARAWSQEGP 1402
Query: 3603 GAYTSTDTH---SALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVG 3657
H L++GG H + + GF+GCV+ + + P+ P G
Sbjct: 1403 HRQHQGAEHPQPHTLFVGGLPASSHSSK-LPVTVGFSGCVKRLRLHGRPLGAPTRMAG 1459
>BC013770-1|AAH13770.1| 530|Homo sapiens netrin G2 protein.
Length = 530
Score = 171 bits (415), Expect = 5e-41
Identities = 132/436 (30%), Positives = 192/436 (44%), Gaps = 64/436 (14%)
Query: 37 CDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+N HPP D T+WQS SR E N+T+ + + V
Sbjct: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDS----VICST 148
RP + VLEKS D G+T++P+Q++++ DC FG + + S V+C+
Sbjct: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
Query: 149 EYSKIVPLEDGEIPISLLNDR------PS----SNMYF---NSSVLQEWTRATNVRLRLL 195
EYS+ + + + DR P N+Y ++ L+E+ T++R+RLL
Sbjct: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
Query: 196 RTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCR 255
R LG V R++ +YFY+I +I + GRC CN HA+ C + G+L C
Sbjct: 258 RPA--LGGTY-VQREN---LYKYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CE 306
Query: 256 CQHNTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP------CNCHNHTTECTYDP 304
C+HNT GP C KC F + WR + +C C C+ H+ C+Y
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGNCECYGHSNRCSY-- 364
Query: 305 EIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD 364
ID + C++C+HNT G +C CR YYR D+ +VC C C+
Sbjct: 365 -ID-----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 365 PHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPT 421
S + E+G CECR P C C ++ C P C+ L G C
Sbjct: 413 QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN 472
Query: 422 DGLCPCKYNYAGKSCE 437
C C Y G CE
Sbjct: 473 Q-RCACPRGYTGVRCE 487
Score = 83.0 bits (196), Expect = 2e-14
Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 41/212 (19%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 281 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
Query: 405 PCTCNLNGTEGE--------HCTPTDGL----C-PCKYNYAGKSCEICEDGYY---SPE- 447
P C G+ G C+ D L C CK+N G+ C+ C GYY S E
Sbjct: 341 PNACAAAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 400
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C C CN +GSV C++ TG C C+ +G C+ C +Y C P CD
Sbjct: 401 DDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCD-- 457
Query: 503 GTEPSICDD-----VSGQCICKAGFGGPRCDQ 529
+ +C + + +C C G+ G RC+Q
Sbjct: 458 -DDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Score = 81.4 bits (192), Expect = 6e-14
Identities = 63/222 (28%), Positives = 85/222 (38%), Gaps = 27/222 (12%)
Query: 428 KYNYAGKSCEI---CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTC-KSKYSGRTCNQ 483
KY YA + E+ C+ ++ C E GS+ C+ T C K K + RT +
Sbjct: 273 KYFYAISNIEVIGRCKCNLHANLCSMRE----GSLQCECEHNTTGPDCGKCKKNFRTRSW 328
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSI-CDDVSGQCI------------CKAGFGGPRCDQC 530
Y P P C +G+ + C S +C CK G C C
Sbjct: 329 RAGSYLPLPHGSPNACAAAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHC 388
Query: 531 LSGYYMQ---VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
GYY L E C+ CNC+ GS C+ G C C G +CD C P +Y
Sbjct: 389 RLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWR 448
Query: 588 PDCLSCNCDVSGSI---GSTCDDNGLCHCKSNFDGAKCDTCR 626
C CD + G TC N C C + G +C+ R
Sbjct: 449 QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 490
Score = 76.2 bits (179), Expect = 2e-12
Identities = 65/209 (31%), Positives = 87/209 (41%), Gaps = 34/209 (16%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYC----------AAGYYGIPEDTD---LHT 1870
N A C + E GSL C C+ G C C A Y +P +
Sbjct: 290 NLHANLCSMRE-GSL-QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAA 347
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSING-DCLKCVNNTAGAACNLCAPGFY--GDA-IFSKN 1926
G + C C G+ N D +N C+ C +NT G C C G+Y G A + +N
Sbjct: 348 GSFGN-CECYGHSNRCS--YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
Query: 1927 -CTACICDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C++ G D + TG C CR G G KCD C P H+ GC P C +
Sbjct: 405 VCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVCD--DD 459
Query: 1985 STQCDD-----DNGQCRCAKGVTGKQCDQ 2008
C + N +C C +G TG +C+Q
Sbjct: 460 QLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Score = 68.1 bits (159), Expect = 6e-10
Identities = 61/199 (30%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 1341 LCDFM-GSTELEC--NTFGGQC-PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI--- 1393
LC GS + EC NT G C CK N RT S Y P+ P C +
Sbjct: 295 LCSMREGSLQCECEHNTTGPDCGKCKKNF--RTRSWRAGSYLPLPHGSPNACAAAGSFGN 352
Query: 1394 CDDNG--------------MCI-CPKNVEGENCDRCK-PYTFN----FDVQRGCDDCNCN 1433
C+ G C+ C N G++C C+ Y N D + C +CNCN
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD---VC 1490
+G V ++ C ++G C CRE G CD C+P HY CY C+ C
Sbjct: 413 QIGSVHDR--CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
Query: 1491 DQNTAQCYCKTNVRGQACD 1509
QN +C C G C+
Sbjct: 470 LQN-QRCACPRGYTGVRCE 487
Score = 64.1 bits (149), Expect = 9e-09
Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 32/210 (15%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCL---------SGYYMQVL-GRERQCV 546
C C+ S+ + S QC C+ GP C +C +G Y+ + G C
Sbjct: 287 CKCNLHANLCSMREG-SLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
Query: 547 PC----NCDPTGSTSTSCSADG----KC-NCLTNFGGAQCDQCSPGYYKYPD-------- 589
NC+ G ++ D C +C N G C C GYY+
Sbjct: 346 AAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 405
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C+ CNC+ GS+ C++ G C C+ G KCD C Y C CD +
Sbjct: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ- 464
Query: 650 AGCGSVPAGELCQCKDRVQGRICND--CKP 677
G+ + C C G C C P
Sbjct: 465 -NGGTCLQNQRCACPRGYTGVRCEQPRCDP 493
Score = 61.3 bits (142), Expect = 6e-08
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 23/153 (15%)
Query: 654 SVPAGEL-CQCKDRVQGRICNDCKPLY----WNLQEYNPFGCEQCN-CNLAGTLNSLGAC 707
S+ G L C+C+ G C CK + W Y P N C AG+ + C
Sbjct: 297 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGNC-EC 355
Query: 708 NTKSGQCV------------CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGG 752
S +C CK + + C C G+YR + +D C EC+C+ G
Sbjct: 356 YGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
S+ + C++T G C C G +CD + HY+
Sbjct: 416 SVHDRCNET-GFCECREGAAGPKCDDCLPTHYW 447
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY-------NYPACEECNCDPRGV 645
C C++ ++ S + + C C+ N G C C++ F +Y + +
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAA 346
Query: 646 TASFAGCGSVPAGELCQ------------CKDRVQGRICNDCKPLYWN-----LQEYNPF 688
SF C C CK +G+ C C+ Y+ L + N
Sbjct: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C +CNCN G+++ CN ++G C C++ +CD CL Y Q GC C
Sbjct: 406 -CIECNCNQIGSVHD--RCN-ETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVC 456
Query: 749 DIGGSIDNNCDKT--TGQCHCHSRVEGRRCDQP 779
D + N +C C G RC+QP
Sbjct: 457 DDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 29/154 (18%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRGC-------DDCNCNPLGVVGNQLQCEADSGKCA 1452
C C N G +C +CK + G C G GN +C S +C+
Sbjct: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGN-CECYGHSNRCS 363
Query: 1453 ------------CRENVRGRVCDHCVPGHYA-----FPD---CYQCTCNRHGTTYDVCDQ 1492
C+ N RG+ C HC G+Y D C +C CN+ G+ +D C++
Sbjct: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
T C C+ G CD C ++ Q P+ C
Sbjct: 424 -TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 456
Score = 59.3 bits (137), Expect = 3e-07
Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGYH--GDATVGTPRDCLICACP 1818
C+C GHS++C +N C++C NT G HC+ C GY+ G A + C+ C C
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC- 411
Query: 1819 MPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCEYCAAGYY 1860
N D +E G C C+ G G +C+ C +Y
Sbjct: 412 -----NQIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHY 446
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 15/142 (10%)
Query: 1946 TCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCA 1998
TCV C+ G+ C C ++ L+ C CNC I S +C++ G C C
Sbjct: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECR 430
Query: 1999 KGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV---GFMCNATGQCECLPGVIGEKCDR 2055
+G G +CD C +Y + GC C+ + G C +C C G G +C++
Sbjct: 431 EGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Query: 2056 CPERWVLIPQEGCLECDSCTDA 2077
R +G L+CD A
Sbjct: 489 --PRCDPADDDGGLDCDRAPGA 508
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-----CPSTA 1392
C C+ +GS CN G C C+ G C C +Y C P C C +
Sbjct: 409 CNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467
Query: 1393 ICDDNGMCICPKNVEGENCD--RCKP 1416
C N C CP+ G C+ RC P
Sbjct: 468 TCLQNQRCACPRGYTGVRCEQPRCDP 493
Score = 41.1 bits (92), Expect = 0.073
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 28/128 (21%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG C+ C G+YR S C+ C CN D+C+ TG C C +
Sbjct: 376 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFC-ECREGA 433
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS---CNCQP 1845
G C+ C+ ++ + C C ++ L C G+ + C C
Sbjct: 434 AGPKCDDCLPTHY------WRQGCYPNVC------DDDQLLC--QNGGTCLQNQRCACPR 479
Query: 1846 GYGGARCE 1853
GY G RCE
Sbjct: 480 GYTGVRCE 487
Score = 37.5 bits (83), Expect = 0.90
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 17/79 (21%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE----------EYFNLQDDNPDGC 1526
+C CN H + + + QC C+ N G C CK+ Y L +P+ C
Sbjct: 286 RCKCNLHANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
Query: 1527 T------KCFCFGKTTRCS 1539
C C+G + RCS
Sbjct: 345 AAAGSFGNCECYGHSNRCS 363
Score = 35.1 bits (77), Expect = 4.8
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 1478 CTCNRHGTTYDVCD-QNTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFC 1531
C C H D N C CK N RGQ C C+ Y+ + + D+ + C +C C
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411
>AL353631-2|CAI16125.1| 530|Homo sapiens netrin G2 protein.
Length = 530
Score = 171 bits (415), Expect = 5e-41
Identities = 132/436 (30%), Positives = 192/436 (44%), Gaps = 64/436 (14%)
Query: 37 CDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+N HPP D T+WQS SR E N+T+ + + V
Sbjct: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDS----VICST 148
RP + VLEKS D G+T++P+Q++++ DC FG + + S V+C+
Sbjct: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
Query: 149 EYSKIVPLEDGEIPISLLNDR------PS----SNMYF---NSSVLQEWTRATNVRLRLL 195
EYS+ + + + DR P N+Y ++ L+E+ T++R+RLL
Sbjct: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
Query: 196 RTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCR 255
R LG V R++ +YFY+I +I + GRC CN HA+ C + G+L C
Sbjct: 258 RPA--LGGTY-VQREN---LYKYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CE 306
Query: 256 CQHNTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP------CNCHNHTTECTYDP 304
C+HNT GP C KC F + WR + +C C C+ H+ C+Y
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY-- 364
Query: 305 EIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD 364
ID + C++C+HNT G +C CR YYR D+ +VC C C+
Sbjct: 365 -ID-----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 365 PHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPT 421
S + E+G CECR P C C ++ C P C+ L G C
Sbjct: 413 QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN 472
Query: 422 DGLCPCKYNYAGKSCE 437
C C Y G CE
Sbjct: 473 Q-RCACPRGYTGVRCE 487
Score = 83.4 bits (197), Expect = 1e-14
Identities = 64/222 (28%), Positives = 86/222 (38%), Gaps = 27/222 (12%)
Query: 428 KYNYAGKSCEI---CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTC-KSKYSGRTCNQ 483
KY YA + E+ C+ ++ C E GS+ C+ T C K K + RT +
Sbjct: 273 KYFYAISNIEVIGRCKCNLHANLCSMRE----GSLQCECEHNTTGPDCGKCKKNFRTRSW 328
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSI-CDDVSGQCI------------CKAGFGGPRCDQC 530
Y P P C T+G+ + C S +C CK G C C
Sbjct: 329 RAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHC 388
Query: 531 LSGYYMQ---VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
GYY L E C+ CNC+ GS C+ G C C G +CD C P +Y
Sbjct: 389 RLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWR 448
Query: 588 PDCLSCNCDVSGSI---GSTCDDNGLCHCKSNFDGAKCDTCR 626
C CD + G TC N C C + G +C+ R
Sbjct: 449 QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 490
Score = 83.0 bits (196), Expect = 2e-14
Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 41/212 (19%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 281 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
Query: 405 PCTCNLNGTEGE--------HCTPTDGL----C-PCKYNYAGKSCEICEDGYY---SPE- 447
P C G+ G C+ D L C CK+N G+ C+ C GYY S E
Sbjct: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 400
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C C CN +GSV C++ TG C C+ +G C+ C +Y C P CD
Sbjct: 401 DDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCD-- 457
Query: 503 GTEPSICDD-----VSGQCICKAGFGGPRCDQ 529
+ +C + + +C C G+ G RC+Q
Sbjct: 458 -DDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Score = 77.4 bits (182), Expect = 9e-13
Identities = 65/208 (31%), Positives = 86/208 (41%), Gaps = 32/208 (15%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYC----------AAGYYGIPEDTD--LHTG 1871
N A C + E GSL C C+ G C C A Y +P + T
Sbjct: 290 NLHANLCSMRE-GSL-QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATA 347
Query: 1872 DYCKPCNCSGNINPQDPGSCDSING-DCLKCVNNTAGAACNLCAPGFY--GDA-IFSKN- 1926
C C G+ N D +N C+ C +NT G C C G+Y G A + +N
Sbjct: 348 GSFGNCECYGHSNRCS--YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 405
Query: 1927 CTACICDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASES 1985
C C C++ G D + TG C CR G G KCD C P H+ GC P C +
Sbjct: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVCD--DDQ 460
Query: 1986 TQCDD-----DNGQCRCAKGVTGKQCDQ 2008
C + N +C C +G TG +C+Q
Sbjct: 461 LLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Score = 68.1 bits (159), Expect = 6e-10
Identities = 61/199 (30%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 1341 LCDFM-GSTELEC--NTFGGQC-PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI--- 1393
LC GS + EC NT G C CK N RT S Y P+ P C +
Sbjct: 295 LCSMREGSLQCECEHNTTGPDCGKCKKNF--RTRSWRAGSYLPLPHGSPNACATAGSFGN 352
Query: 1394 CDDNG--------------MCI-CPKNVEGENCDRCK-PYTFN----FDVQRGCDDCNCN 1433
C+ G C+ C N G++C C+ Y N D + C +CNCN
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD---VC 1490
+G V ++ C ++G C CRE G CD C+P HY CY C+ C
Sbjct: 413 QIGSVHDR--CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
Query: 1491 DQNTAQCYCKTNVRGQACD 1509
QN +C C G C+
Sbjct: 470 LQN-QRCACPRGYTGVRCE 487
Score = 64.1 bits (149), Expect = 9e-09
Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 32/210 (15%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCL---------SGYYMQVL-GRERQCV 546
C C+ S+ + S QC C+ GP C +C +G Y+ + G C
Sbjct: 287 CKCNLHANLCSMREG-SLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
Query: 547 PC----NCDPTGSTSTSCSADG----KC-NCLTNFGGAQCDQCSPGYYKYPD-------- 589
NC+ G ++ D C +C N G C C GYY+
Sbjct: 346 TAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 405
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C+ CNC+ GS+ C++ G C C+ G KCD C Y C CD +
Sbjct: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ- 464
Query: 650 AGCGSVPAGELCQCKDRVQGRICND--CKP 677
G+ + C C G C C P
Sbjct: 465 -NGGTCLQNQRCACPRGYTGVRCEQPRCDP 493
Score = 61.3 bits (142), Expect = 6e-08
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 23/153 (15%)
Query: 654 SVPAGEL-CQCKDRVQGRICNDCKPLY----WNLQEYNPFGCEQCN-CNLAGTLNSLGAC 707
S+ G L C+C+ G C CK + W Y P N C AG+ + C
Sbjct: 297 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNC-EC 355
Query: 708 NTKSGQCV------------CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGG 752
S +C CK + + C C G+YR + +D C EC+C+ G
Sbjct: 356 YGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
S+ + C++T G C C G +CD + HY+
Sbjct: 416 SVHDRCNET-GFCECREGAAGPKCDDCLPTHYW 447
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY-------NYPACEECNCDPRGV 645
C C++ ++ S + + C C+ N G C C++ F +Y + +
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
Query: 646 TASFAGCGSVPAGELCQ------------CKDRVQGRICNDCKPLYWN-----LQEYNPF 688
SF C C CK +G+ C C+ Y+ L + N
Sbjct: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C +CNCN G+++ CN ++G C C++ +CD CL Y Q GC C
Sbjct: 406 -CIECNCNQIGSVHD--RCN-ETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVC 456
Query: 749 DIGGSIDNNCDKT--TGQCHCHSRVEGRRCDQP 779
D + N +C C G RC+QP
Sbjct: 457 DDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 29/154 (18%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRGC-------DDCNCNPLGVVGNQLQCEADSGKCA 1452
C C N G +C +CK + G C G GN +C S +C+
Sbjct: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGN-CECYGHSNRCS 363
Query: 1453 ------------CRENVRGRVCDHCVPGHYA-----FPD---CYQCTCNRHGTTYDVCDQ 1492
C+ N RG+ C HC G+Y D C +C CN+ G+ +D C++
Sbjct: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
T C C+ G CD C ++ Q P+ C
Sbjct: 424 -TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 456
Score = 59.3 bits (137), Expect = 3e-07
Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGYH--GDATVGTPRDCLICACP 1818
C+C GHS++C +N C++C NT G HC+ C GY+ G A + C+ C C
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC- 411
Query: 1819 MPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCEYCAAGYY 1860
N D +E G C C+ G G +C+ C +Y
Sbjct: 412 -----NQIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHY 446
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 15/142 (10%)
Query: 1946 TCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCA 1998
TCV C+ G+ C C ++ L+ C CNC I S +C++ G C C
Sbjct: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECR 430
Query: 1999 KGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV---GFMCNATGQCECLPGVIGEKCDR 2055
+G G +CD C +Y + GC C+ + G C +C C G G +C++
Sbjct: 431 EGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Query: 2056 CPERWVLIPQEGCLECDSCTDA 2077
R +G L+CD A
Sbjct: 489 --PRCDPADDDGGLDCDRAPGA 508
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-----CPSTA 1392
C C+ +GS CN G C C+ G C C +Y C P C C +
Sbjct: 409 CNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467
Query: 1393 ICDDNGMCICPKNVEGENCD--RCKP 1416
C N C CP+ G C+ RC P
Sbjct: 468 TCLQNQRCACPRGYTGVRCEQPRCDP 493
Score = 41.1 bits (92), Expect = 0.073
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 28/128 (21%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG C+ C G+YR S C+ C CN D+C+ TG C C +
Sbjct: 376 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFC-ECREGA 433
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS---CNCQP 1845
G C+ C+ ++ + C C ++ L C G+ + C C
Sbjct: 434 AGPKCDDCLPTHY------WRQGCYPNVC------DDDQLLC--QNGGTCLQNQRCACPR 479
Query: 1846 GYGGARCE 1853
GY G RCE
Sbjct: 480 GYTGVRCE 487
Score = 37.5 bits (83), Expect = 0.90
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 17/79 (21%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE----------EYFNLQDDNPDGC 1526
+C CN H + + + QC C+ N G C CK+ Y L +P+ C
Sbjct: 286 RCKCNLHANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
Query: 1527 T------KCFCFGKTTRCS 1539
C C+G + RCS
Sbjct: 345 ATAGSFGNCECYGHSNRCS 363
Score = 35.1 bits (77), Expect = 4.8
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 1478 CTCNRHGTTYDVCD-QNTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFC 1531
C C H D N C CK N RGQ C C+ Y+ + + D+ + C +C C
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411
>AL159997-3|CAI40856.1| 530|Homo sapiens netrin G2 protein.
Length = 530
Score = 171 bits (415), Expect = 5e-41
Identities = 132/436 (30%), Positives = 192/436 (44%), Gaps = 64/436 (14%)
Query: 37 CDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+N HPP D T+WQS SR E N+T+ + + V
Sbjct: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDS----VICST 148
RP + VLEKS D G+T++P+Q++++ DC FG + + S V+C+
Sbjct: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
Query: 149 EYSKIVPLEDGEIPISLLNDR------PS----SNMYF---NSSVLQEWTRATNVRLRLL 195
EYS+ + + + DR P N+Y ++ L+E+ T++R+RLL
Sbjct: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
Query: 196 RTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCR 255
R LG V R++ +YFY+I +I + GRC CN HA+ C + G+L C
Sbjct: 258 RPA--LGGTY-VQREN---LYKYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CE 306
Query: 256 CQHNTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP------CNCHNHTTECTYDP 304
C+HNT GP C KC F + WR + +C C C+ H+ C+Y
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY-- 364
Query: 305 EIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD 364
ID + C++C+HNT G +C CR YYR D+ +VC C C+
Sbjct: 365 -ID-----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 365 PHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPT 421
S + E+G CECR P C C ++ C P C+ L G C
Sbjct: 413 QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN 472
Query: 422 DGLCPCKYNYAGKSCE 437
C C Y G CE
Sbjct: 473 Q-RCACPRGYTGVRCE 487
Score = 83.4 bits (197), Expect = 1e-14
Identities = 64/222 (28%), Positives = 86/222 (38%), Gaps = 27/222 (12%)
Query: 428 KYNYAGKSCEI---CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTC-KSKYSGRTCNQ 483
KY YA + E+ C+ ++ C E GS+ C+ T C K K + RT +
Sbjct: 273 KYFYAISNIEVIGRCKCNLHANLCSMRE----GSLQCECEHNTTGPDCGKCKKNFRTRSW 328
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSI-CDDVSGQCI------------CKAGFGGPRCDQC 530
Y P P C T+G+ + C S +C CK G C C
Sbjct: 329 RAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHC 388
Query: 531 LSGYYMQ---VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
GYY L E C+ CNC+ GS C+ G C C G +CD C P +Y
Sbjct: 389 RLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWR 448
Query: 588 PDCLSCNCDVSGSI---GSTCDDNGLCHCKSNFDGAKCDTCR 626
C CD + G TC N C C + G +C+ R
Sbjct: 449 QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 490
Score = 83.0 bits (196), Expect = 2e-14
Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 41/212 (19%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 281 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
Query: 405 PCTCNLNGTEGE--------HCTPTDGL----C-PCKYNYAGKSCEICEDGYY---SPE- 447
P C G+ G C+ D L C CK+N G+ C+ C GYY S E
Sbjct: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 400
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C C CN +GSV C++ TG C C+ +G C+ C +Y C P CD
Sbjct: 401 DDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCD-- 457
Query: 503 GTEPSICDD-----VSGQCICKAGFGGPRCDQ 529
+ +C + + +C C G+ G RC+Q
Sbjct: 458 -DDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Score = 77.4 bits (182), Expect = 9e-13
Identities = 65/208 (31%), Positives = 86/208 (41%), Gaps = 32/208 (15%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYC----------AAGYYGIPEDTD--LHTG 1871
N A C + E GSL C C+ G C C A Y +P + T
Sbjct: 290 NLHANLCSMRE-GSL-QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATA 347
Query: 1872 DYCKPCNCSGNINPQDPGSCDSING-DCLKCVNNTAGAACNLCAPGFY--GDA-IFSKN- 1926
C C G+ N D +N C+ C +NT G C C G+Y G A + +N
Sbjct: 348 GSFGNCECYGHSNRCS--YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 405
Query: 1927 CTACICDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASES 1985
C C C++ G D + TG C CR G G KCD C P H+ GC P C +
Sbjct: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVCD--DDQ 460
Query: 1986 TQCDD-----DNGQCRCAKGVTGKQCDQ 2008
C + N +C C +G TG +C+Q
Sbjct: 461 LLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Score = 68.1 bits (159), Expect = 6e-10
Identities = 61/199 (30%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 1341 LCDFM-GSTELEC--NTFGGQC-PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI--- 1393
LC GS + EC NT G C CK N RT S Y P+ P C +
Sbjct: 295 LCSMREGSLQCECEHNTTGPDCGKCKKNF--RTRSWRAGSYLPLPHGSPNACATAGSFGN 352
Query: 1394 CDDNG--------------MCI-CPKNVEGENCDRCK-PYTFN----FDVQRGCDDCNCN 1433
C+ G C+ C N G++C C+ Y N D + C +CNCN
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD---VC 1490
+G V ++ C ++G C CRE G CD C+P HY CY C+ C
Sbjct: 413 QIGSVHDR--CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
Query: 1491 DQNTAQCYCKTNVRGQACD 1509
QN +C C G C+
Sbjct: 470 LQN-QRCACPRGYTGVRCE 487
Score = 64.1 bits (149), Expect = 9e-09
Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 32/210 (15%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCL---------SGYYMQVL-GRERQCV 546
C C+ S+ + S QC C+ GP C +C +G Y+ + G C
Sbjct: 287 CKCNLHANLCSMREG-SLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
Query: 547 PC----NCDPTGSTSTSCSADG----KC-NCLTNFGGAQCDQCSPGYYKYPD-------- 589
NC+ G ++ D C +C N G C C GYY+
Sbjct: 346 TAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 405
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C+ CNC+ GS+ C++ G C C+ G KCD C Y C CD +
Sbjct: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ- 464
Query: 650 AGCGSVPAGELCQCKDRVQGRICND--CKP 677
G+ + C C G C C P
Sbjct: 465 -NGGTCLQNQRCACPRGYTGVRCEQPRCDP 493
Score = 61.3 bits (142), Expect = 6e-08
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 23/153 (15%)
Query: 654 SVPAGEL-CQCKDRVQGRICNDCKPLY----WNLQEYNPFGCEQCN-CNLAGTLNSLGAC 707
S+ G L C+C+ G C CK + W Y P N C AG+ + C
Sbjct: 297 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNC-EC 355
Query: 708 NTKSGQCV------------CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGG 752
S +C CK + + C C G+YR + +D C EC+C+ G
Sbjct: 356 YGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
S+ + C++T G C C G +CD + HY+
Sbjct: 416 SVHDRCNET-GFCECREGAAGPKCDDCLPTHYW 447
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY-------NYPACEECNCDPRGV 645
C C++ ++ S + + C C+ N G C C++ F +Y + +
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
Query: 646 TASFAGCGSVPAGELCQ------------CKDRVQGRICNDCKPLYWN-----LQEYNPF 688
SF C C CK +G+ C C+ Y+ L + N
Sbjct: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C +CNCN G+++ CN ++G C C++ +CD CL Y Q GC C
Sbjct: 406 -CIECNCNQIGSVHD--RCN-ETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVC 456
Query: 749 DIGGSIDNNCDKT--TGQCHCHSRVEGRRCDQP 779
D + N +C C G RC+QP
Sbjct: 457 DDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 29/154 (18%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRGC-------DDCNCNPLGVVGNQLQCEADSGKCA 1452
C C N G +C +CK + G C G GN +C S +C+
Sbjct: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGN-CECYGHSNRCS 363
Query: 1453 ------------CRENVRGRVCDHCVPGHYA-----FPD---CYQCTCNRHGTTYDVCDQ 1492
C+ N RG+ C HC G+Y D C +C CN+ G+ +D C++
Sbjct: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
T C C+ G CD C ++ Q P+ C
Sbjct: 424 -TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 456
Score = 59.3 bits (137), Expect = 3e-07
Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGYH--GDATVGTPRDCLICACP 1818
C+C GHS++C +N C++C NT G HC+ C GY+ G A + C+ C C
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC- 411
Query: 1819 MPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCEYCAAGYY 1860
N D +E G C C+ G G +C+ C +Y
Sbjct: 412 -----NQIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHY 446
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 15/142 (10%)
Query: 1946 TCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCA 1998
TCV C+ G+ C C ++ L+ C CNC I S +C++ G C C
Sbjct: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECR 430
Query: 1999 KGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV---GFMCNATGQCECLPGVIGEKCDR 2055
+G G +CD C +Y + GC C+ + G C +C C G G +C++
Sbjct: 431 EGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
Query: 2056 CPERWVLIPQEGCLECDSCTDA 2077
R +G L+CD A
Sbjct: 489 --PRCDPADDDGGLDCDRAPGA 508
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-----CPSTA 1392
C C+ +GS CN G C C+ G C C +Y C P C C +
Sbjct: 409 CNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467
Query: 1393 ICDDNGMCICPKNVEGENCD--RCKP 1416
C N C CP+ G C+ RC P
Sbjct: 468 TCLQNQRCACPRGYTGVRCEQPRCDP 493
Score = 41.1 bits (92), Expect = 0.073
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 28/128 (21%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG C+ C G+YR S C+ C CN D+C+ TG C C +
Sbjct: 376 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFC-ECREGA 433
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS---CNCQP 1845
G C+ C+ ++ + C C ++ L C G+ + C C
Sbjct: 434 AGPKCDDCLPTHY------WRQGCYPNVC------DDDQLLC--QNGGTCLQNQRCACPR 479
Query: 1846 GYGGARCE 1853
GY G RCE
Sbjct: 480 GYTGVRCE 487
Score = 37.5 bits (83), Expect = 0.90
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 17/79 (21%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE----------EYFNLQDDNPDGC 1526
+C CN H + + + QC C+ N G C CK+ Y L +P+ C
Sbjct: 286 RCKCNLHANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
Query: 1527 T------KCFCFGKTTRCS 1539
C C+G + RCS
Sbjct: 345 ATAGSFGNCECYGHSNRCS 363
Score = 35.1 bits (77), Expect = 4.8
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 1478 CTCNRHGTTYDVCD-QNTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFC 1531
C C H D N C CK N RGQ C C+ Y+ + + D+ + C +C C
Sbjct: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411
>AB058760-1|BAB47486.2| 549|Homo sapiens KIAA1857 protein protein.
Length = 549
Score = 171 bits (415), Expect = 5e-41
Identities = 132/436 (30%), Positives = 192/436 (44%), Gaps = 64/436 (14%)
Query: 37 CDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+N HPP D T+WQS SR E N+T+ + + V
Sbjct: 100 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 159
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDS----VICST 148
RP + VLEKS D G+T++P+Q++++ DC FG + + S V+C+
Sbjct: 160 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 216
Query: 149 EYSKIVPLEDGEIPISLLNDR------PS----SNMYF---NSSVLQEWTRATNVRLRLL 195
EYS+ + + + DR P N+Y ++ L+E+ T++R+RLL
Sbjct: 217 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 276
Query: 196 RTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCR 255
R LG V R++ +YFY+I +I + GRC CN HA+ C + G+L C
Sbjct: 277 RPA--LGGTY-VQREN---LYKYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CE 325
Query: 256 CQHNTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP------CNCHNHTTECTYDP 304
C+HNT GP C KC F + WR + +C C C+ H+ C+Y
Sbjct: 326 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGNCECYGHSNRCSY-- 383
Query: 305 EIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCD 364
ID + C++C+HNT G +C CR YYR D+ +VC C C+
Sbjct: 384 -ID-----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 431
Query: 365 PHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPT 421
S + E+G CECR P C C ++ C P C+ L G C
Sbjct: 432 QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN 491
Query: 422 DGLCPCKYNYAGKSCE 437
C C Y G CE
Sbjct: 492 Q-RCACPRGYTGVRCE 506
Score = 83.0 bits (196), Expect = 2e-14
Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 41/212 (19%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 300 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 359
Query: 405 PCTCNLNGTEGE--------HCTPTDGL----C-PCKYNYAGKSCEICEDGYY---SPE- 447
P C G+ G C+ D L C CK+N G+ C+ C GYY S E
Sbjct: 360 PNACAAAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 419
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C C CN +GSV C++ TG C C+ +G C+ C +Y C P CD
Sbjct: 420 DDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCD-- 476
Query: 503 GTEPSICDD-----VSGQCICKAGFGGPRCDQ 529
+ +C + + +C C G+ G RC+Q
Sbjct: 477 -DDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 507
Score = 81.4 bits (192), Expect = 6e-14
Identities = 63/222 (28%), Positives = 85/222 (38%), Gaps = 27/222 (12%)
Query: 428 KYNYAGKSCEI---CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTC-KSKYSGRTCNQ 483
KY YA + E+ C+ ++ C E GS+ C+ T C K K + RT +
Sbjct: 292 KYFYAISNIEVIGRCKCNLHANLCSMRE----GSLQCECEHNTTGPDCGKCKKNFRTRSW 347
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSI-CDDVSGQCI------------CKAGFGGPRCDQC 530
Y P P C +G+ + C S +C CK G C C
Sbjct: 348 RAGSYLPLPHGSPNACAAAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHC 407
Query: 531 LSGYYMQ---VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
GYY L E C+ CNC+ GS C+ G C C G +CD C P +Y
Sbjct: 408 RLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWR 467
Query: 588 PDCLSCNCDVSGSI---GSTCDDNGLCHCKSNFDGAKCDTCR 626
C CD + G TC N C C + G +C+ R
Sbjct: 468 QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 509
Score = 76.2 bits (179), Expect = 2e-12
Identities = 65/209 (31%), Positives = 87/209 (41%), Gaps = 34/209 (16%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYC----------AAGYYGIPEDTD---LHT 1870
N A C + E GSL C C+ G C C A Y +P +
Sbjct: 309 NLHANLCSMRE-GSL-QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAA 366
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSING-DCLKCVNNTAGAACNLCAPGFY--GDA-IFSKN 1926
G + C C G+ N D +N C+ C +NT G C C G+Y G A + +N
Sbjct: 367 GSFGN-CECYGHSNRCS--YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 423
Query: 1927 -CTACICDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C++ G D + TG C CR G G KCD C P H+ GC P C +
Sbjct: 424 VCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVCD--DD 478
Query: 1985 STQCDD-----DNGQCRCAKGVTGKQCDQ 2008
C + N +C C +G TG +C+Q
Sbjct: 479 QLLCQNGGTCLQNQRCACPRGYTGVRCEQ 507
Score = 68.1 bits (159), Expect = 6e-10
Identities = 61/199 (30%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 1341 LCDFM-GSTELEC--NTFGGQC-PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI--- 1393
LC GS + EC NT G C CK N RT S Y P+ P C +
Sbjct: 314 LCSMREGSLQCECEHNTTGPDCGKCKKNF--RTRSWRAGSYLPLPHGSPNACAAAGSFGN 371
Query: 1394 CDDNG--------------MCI-CPKNVEGENCDRCK-PYTFN----FDVQRGCDDCNCN 1433
C+ G C+ C N G++C C+ Y N D + C +CNCN
Sbjct: 372 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 431
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD---VC 1490
+G V ++ C ++G C CRE G CD C+P HY CY C+ C
Sbjct: 432 QIGSVHDR--CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 488
Query: 1491 DQNTAQCYCKTNVRGQACD 1509
QN +C C G C+
Sbjct: 489 LQN-QRCACPRGYTGVRCE 506
Score = 64.1 bits (149), Expect = 9e-09
Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 32/210 (15%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCL---------SGYYMQVL-GRERQCV 546
C C+ S+ + S QC C+ GP C +C +G Y+ + G C
Sbjct: 306 CKCNLHANLCSMREG-SLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 364
Query: 547 PC----NCDPTGSTSTSCSADG----KC-NCLTNFGGAQCDQCSPGYYKYPD-------- 589
NC+ G ++ D C +C N G C C GYY+
Sbjct: 365 AAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 424
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C+ CNC+ GS+ C++ G C C+ G KCD C Y C CD +
Sbjct: 425 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ- 483
Query: 650 AGCGSVPAGELCQCKDRVQGRICND--CKP 677
G+ + C C G C C P
Sbjct: 484 -NGGTCLQNQRCACPRGYTGVRCEQPRCDP 512
Score = 61.3 bits (142), Expect = 6e-08
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 23/153 (15%)
Query: 654 SVPAGEL-CQCKDRVQGRICNDCKPLY----WNLQEYNPFGCEQCN-CNLAGTLNSLGAC 707
S+ G L C+C+ G C CK + W Y P N C AG+ + C
Sbjct: 316 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGNC-EC 374
Query: 708 NTKSGQCV------------CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGG 752
S +C CK + + C C G+YR + +D C EC+C+ G
Sbjct: 375 YGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 434
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
S+ + C++T G C C G +CD + HY+
Sbjct: 435 SVHDRCNET-GFCECREGAAGPKCDDCLPTHYW 466
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY-------NYPACEECNCDPRGV 645
C C++ ++ S + + C C+ N G C C++ F +Y + +
Sbjct: 306 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAA 365
Query: 646 TASFAGCGSVPAGELCQ------------CKDRVQGRICNDCKPLYWN-----LQEYNPF 688
SF C C CK +G+ C C+ Y+ L + N
Sbjct: 366 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 424
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C +CNCN G+++ CN ++G C C++ +CD CL Y Q GC C
Sbjct: 425 -CIECNCNQIGSVHD--RCN-ETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVC 475
Query: 749 DIGGSIDNNCDKT--TGQCHCHSRVEGRRCDQP 779
D + N +C C G RC+QP
Sbjct: 476 DDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 508
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 29/154 (18%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRGC-------DDCNCNPLGVVGNQLQCEADSGKCA 1452
C C N G +C +CK + G C G GN +C S +C+
Sbjct: 324 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGN-CECYGHSNRCS 382
Query: 1453 ------------CRENVRGRVCDHCVPGHYA-----FPD---CYQCTCNRHGTTYDVCDQ 1492
C+ N RG+ C HC G+Y D C +C CN+ G+ +D C++
Sbjct: 383 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 442
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
T C C+ G CD C ++ Q P+ C
Sbjct: 443 -TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 475
Score = 59.3 bits (137), Expect = 3e-07
Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGYH--GDATVGTPRDCLICACP 1818
C+C GHS++C +N C++C NT G HC+ C GY+ G A + C+ C C
Sbjct: 372 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC- 430
Query: 1819 MPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCEYCAAGYY 1860
N D +E G C C+ G G +C+ C +Y
Sbjct: 431 -----NQIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHY 465
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 15/142 (10%)
Query: 1946 TCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCA 1998
TCV C+ G+ C C ++ L+ C CNC I S +C++ G C C
Sbjct: 391 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECR 449
Query: 1999 KGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV---GFMCNATGQCECLPGVIGEKCDR 2055
+G G +CD C +Y + GC C+ + G C +C C G G +C++
Sbjct: 450 EGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 507
Query: 2056 CPERWVLIPQEGCLECDSCTDA 2077
R +G L+CD A
Sbjct: 508 --PRCDPADDDGGLDCDRAPGA 527
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-----CPSTA 1392
C C+ +GS CN G C C+ G C C +Y C P C C +
Sbjct: 428 CNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 486
Query: 1393 ICDDNGMCICPKNVEGENCD--RCKP 1416
C N C CP+ G C+ RC P
Sbjct: 487 TCLQNQRCACPRGYTGVRCEQPRCDP 512
Score = 41.1 bits (92), Expect = 0.073
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 28/128 (21%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG C+ C G+YR S C+ C CN D+C+ TG C C +
Sbjct: 395 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFC-ECREGA 452
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS---CNCQP 1845
G C+ C+ ++ + C C ++ L C G+ + C C
Sbjct: 453 AGPKCDDCLPTHY------WRQGCYPNVC------DDDQLLC--QNGGTCLQNQRCACPR 498
Query: 1846 GYGGARCE 1853
GY G RCE
Sbjct: 499 GYTGVRCE 506
Score = 37.5 bits (83), Expect = 0.90
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 17/79 (21%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE----------EYFNLQDDNPDGC 1526
+C CN H + + + QC C+ N G C CK+ Y L +P+ C
Sbjct: 305 RCKCNLHANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 363
Query: 1527 T------KCFCFGKTTRCS 1539
C C+G + RCS
Sbjct: 364 AAAGSFGNCECYGHSNRCS 382
Score = 35.1 bits (77), Expect = 4.8
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 1478 CTCNRHGTTYDVCD-QNTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFC 1531
C C H D N C CK N RGQ C C+ Y+ + + D+ + C +C C
Sbjct: 372 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 430
>AL590427-6|CAH73381.1| 539|Homo sapiens netrin G1 protein.
Length = 539
Score = 169 bits (410), Expect = 2e-40
Identities = 128/434 (29%), Positives = 194/434 (44%), Gaps = 60/434 (13%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP-------CNCHNHTTECTYDPEI 306
NT GP C KC ++ + W +C P C C H+ C+Y I
Sbjct: 320 NTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY---I 376
Query: 307 DEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPH 366
D + C++C+HNT G +C CR Y+R + D+ +VC C C+P
Sbjct: 377 DLLNTVI-----------CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPL 425
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPTDG 423
S + SG CEC+ P C C G + C+P C+ L+ G C +
Sbjct: 426 GSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTC-HNNV 484
Query: 424 LCPCKYNYAGKSCE 437
C C Y G CE
Sbjct: 485 RCLCPAAYTGILCE 498
Score = 86.2 bits (204), Expect = 2e-15
Identities = 61/207 (29%), Positives = 83/207 (40%), Gaps = 33/207 (15%)
Query: 451 CECNTVGSVS-YVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP---------------TC 494
C+CN +V Y KLT C C+ +G C +C+ Y P TC
Sbjct: 297 CKCNLHATVCVYDNSKLT--CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC 354
Query: 495 KP-------CNCDTSGTEPSICDDVSGQ-CI-CKAGFGGPRCDQCLSGYYMQV---LGRE 542
P C C S D ++ C+ CK G C+ C GY+ L E
Sbjct: 355 IPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDE 414
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCD---VSG 599
C+ C C+P GS C+ G C C T G +CD+C PG + C CD +
Sbjct: 415 NVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHC 474
Query: 600 SIGSTCDDNGLCHCKSNFDGAKCDTCR 626
G TC +N C C + + G C+ R
Sbjct: 475 QNGGTCHNNVRCLCPAAYTGILCEKLR 501
Score = 73.7 bits (173), Expect = 1e-11
Identities = 57/198 (28%), Positives = 84/198 (42%), Gaps = 31/198 (15%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLH------TGDYCKP-------CNCSG 1881
+ S ++C C+ G C C Y G P + T + C P C C G
Sbjct: 309 DNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368
Query: 1882 NINPQDPGSCDSINGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFG 1936
+ N D +N C+ C +NT G C LC G++ +A + +N C C C+ G
Sbjct: 369 HSNRCS--YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLG 426
Query: 1937 -MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----- 1990
+ D + +G C C+ G G KCD C P G + GC P C +E C +
Sbjct: 427 SIHDRCNGSGFCECKTGTTGPKCDECLP---GNSWHYGCQPNVCD--NELLHCQNGGTCH 481
Query: 1991 DNGQCRCAKGVTGKQCDQ 2008
+N +C C TG C++
Sbjct: 482 NNVRCLCPAAYTGILCEK 499
Score = 67.7 bits (158), Expect = 7e-10
Identities = 50/153 (32%), Positives = 69/153 (45%), Gaps = 26/153 (16%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACP 1818
C+C GHS++C +NT IC++C NT G HCE C GY + A + C+ C C
Sbjct: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC- 422
Query: 1819 MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCN 1878
P + C NGS C C+ G G +C+ C G H G C+P
Sbjct: 423 --NPLGSIHDRC----NGSGF-CECKTGTTGPKCDECLPG-------NSWHYG--CQPNV 466
Query: 1879 CSGN-INPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C ++ Q+ G+C + N CL C G C
Sbjct: 467 CDNELLHCQNGGTCHN-NVRCL-CPAAYTGILC 497
Score = 66.5 bits (155), Expect = 2e-09
Identities = 66/247 (26%), Positives = 95/247 (38%), Gaps = 42/247 (17%)
Query: 1308 ASYNYYISPNET-GLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQC-PCKPNV 1365
A Y Y IS + G C+ + + Y++ C C E NT G C CK N
Sbjct: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--------EHNTTGPDCGKCKKNY 333
Query: 1366 IGR-------------TCSACRTGYYGFPNCRPC--HCPSTAICD--DNGMCI-CPKNVE 1407
GR T + C NC C H + D + +C+ C N
Sbjct: 334 QGRPWSPGSYLPIPKGTANTCIPSISSIGNCE-CFGHSNRCSYIDLLNTVICVSCKHNTR 392
Query: 1408 GENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC 1462
G++C+ C+ F D + C +C CNPLG + ++ C SG C C+ G C
Sbjct: 393 GQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR--CNG-SGFCECKTGTTGPKC 449
Query: 1463 DHCVPGHYAFPDCYQCTCNR---HGTTYDVCDQNTAQCYCKTNVRGQACDTCK-EEYFNL 1518
D C+PG+ C C+ H C N +C C G C+ + EE +
Sbjct: 450 DECLPGNSWHYGCQPNVCDNELLHCQNGGTC-HNNVRCLCPAAYTGILCEKLRCEEAGSC 508
Query: 1519 QDDNPDG 1525
D+ G
Sbjct: 509 GSDSGQG 515
Score = 64.1 bits (149), Expect = 9e-09
Identities = 48/174 (27%), Positives = 67/174 (38%), Gaps = 31/174 (17%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY---------YMQV-LGRERQCV 546
C C+ T + D+ C C+ GP C +C Y Y+ + G C+
Sbjct: 297 CKCNLHATV-CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
Query: 547 PC-----NCDPTGSTSTSCSADGKCN------CLTNFGGAQCDQCSPGYYKYPD------ 589
P NC+ G S CS N C N G C+ C GY++
Sbjct: 356 PSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDE 414
Query: 590 --CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
C+ C C+ GSI C+ +G C CK+ G KCD C + C+ CD
Sbjct: 415 NVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD 468
Score = 58.8 bits (136), Expect = 3e-07
Identities = 57/221 (25%), Positives = 82/221 (37%), Gaps = 46/221 (20%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H T C YD +L+ + C+HNT G +C KC+ Y RP+
Sbjct: 297 CKCNLHATVCVYD----NSKLTCE-------------CEHNTTGPDCGKCKKNYQGRPWS 339
Query: 350 K-RWDELDVCQPCQCDPHFST-GNCE--EESGRC------------ECRPEFQPPDCSSC 393
+ + C P S+ GNCE S RC C+ + C C
Sbjct: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELC 399
Query: 394 AYGYF--------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG--- 442
GYF D C C CN G+ + C + G C CK G C+ C G
Sbjct: 400 RLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGS-GFCECKTGTTGPKCDECLPGNSW 458
Query: 443 YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ 483
+Y + C+ + + C C + Y+G C +
Sbjct: 459 HYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
Score = 52.4 bits (120), Expect = 3e-05
Identities = 38/139 (27%), Positives = 60/139 (43%), Gaps = 23/139 (16%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEYNPFGCEQCNCNLAGTLNSLGACNT--KSGQC 714
C+C+ G C CK Y W+ Y P N + +++S+G C S +C
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP-SISSIGNCECFGHSNRC 373
Query: 715 ------------VCKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNCD 759
CK + + C+ C G++R Q +D C EC C+ GSI + C+
Sbjct: 374 SYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN 433
Query: 760 KTTGQCHCHSRVEGRRCDQ 778
+G C C + G +CD+
Sbjct: 434 -GSGFCECKTGTTGPKCDE 451
Score = 52.0 bits (119), Expect = 4e-05
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 1941 DSTTGTCVCRPGVIGEKCDRCAPDHWGL------------NTGLGCTPC-----NCGIAS 1983
D++ TC C G C +C ++ G T C P NC
Sbjct: 309 DNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368
Query: 1984 ESTQCDD----DNGQC-RCAKGVTGKQCDQCAAGFWNYT------KDGCDHCNCNTGYSV 2032
S +C + C C G+ C+ C G++ ++ C C CN S+
Sbjct: 369 HSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSI 428
Query: 2033 GFMCNATGQCECLPGVIGEKCDRC 2056
CN +G CEC G G KCD C
Sbjct: 429 HDRCNGSGFCECKTGTTGPKCDEC 452
Score = 50.0 bits (114), Expect = 2e-04
Identities = 51/212 (24%), Positives = 79/212 (37%), Gaps = 35/212 (16%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD-PRGVT----- 646
C C++ ++ + C C+ N G C C++ + P P+G
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 647 --ASFAGCGSVPAGELCQ------------CKDRVQGRICNDCKPLYW---NLQEYNPFG 689
+S C C CK +G+ C C+ Y+ + Q +
Sbjct: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG---FYRLQTNDVFGCTEC 746
C +C CN G+++ CN SG C CK +CD+CL G Y Q N V
Sbjct: 417 CIECYCNPLGSIHD--RCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPN-VCDNELL 472
Query: 747 DCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
C GG+ NN +C C + G C++
Sbjct: 473 HCQNGGTCHNNV-----RCLCPAAYTGILCEK 499
Score = 47.6 bits (108), Expect = 8e-04
Identities = 51/193 (26%), Positives = 74/193 (38%), Gaps = 38/193 (19%)
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--------IFSKNCTACI--------CDEFGMADCDS- 1942
+C +NT G C C + G I CI C+ FG ++ S
Sbjct: 316 ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY 375
Query: 1943 ----TTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDD 1991
T CV C+ G+ C+ C ++ L+ C C C + S +C+
Sbjct: 376 IDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG- 434
Query: 1992 NGQCRCAKGVTGKQCDQCAAG-FWNYTKDGCDHCNCNTGY---SVGFMCNATGQCECLPG 2047
+G C C G TG +CD+C G W+Y GC C+ G C+ +C C
Sbjct: 435 SGFCECKTGTTGPKCDECLPGNSWHY---GCQPNVCDNELLHCQNGGTCHNNVRCLCPAA 491
Query: 2048 VIGEKCD--RCPE 2058
G C+ RC E
Sbjct: 492 YTGILCEKLRCEE 504
Score = 39.5 bits (88), Expect = 0.22
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 11/71 (15%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG CE C G++R S C+ C CN D+C+ +G C C T
Sbjct: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN-GSGFC-ECKTGT 444
Query: 1789 IGDHCEFCMSG 1799
G C+ C+ G
Sbjct: 445 TGPKCDECLPG 455
>AL513187-3|CAH73830.1| 539|Homo sapiens netrin G1 protein.
Length = 539
Score = 169 bits (410), Expect = 2e-40
Identities = 128/434 (29%), Positives = 194/434 (44%), Gaps = 60/434 (13%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP-------CNCHNHTTECTYDPEI 306
NT GP C KC ++ + W +C P C C H+ C+Y I
Sbjct: 320 NTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY---I 376
Query: 307 DEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPH 366
D + C++C+HNT G +C CR Y+R + D+ +VC C C+P
Sbjct: 377 DLLNTVI-----------CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPL 425
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPTDG 423
S + SG CEC+ P C C G + C+P C+ L+ G C +
Sbjct: 426 GSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTC-HNNV 484
Query: 424 LCPCKYNYAGKSCE 437
C C Y G CE
Sbjct: 485 RCLCPAAYTGILCE 498
Score = 86.2 bits (204), Expect = 2e-15
Identities = 61/207 (29%), Positives = 83/207 (40%), Gaps = 33/207 (15%)
Query: 451 CECNTVGSVS-YVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP---------------TC 494
C+CN +V Y KLT C C+ +G C +C+ Y P TC
Sbjct: 297 CKCNLHATVCVYDNSKLT--CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC 354
Query: 495 KP-------CNCDTSGTEPSICDDVSGQ-CI-CKAGFGGPRCDQCLSGYYMQV---LGRE 542
P C C S D ++ C+ CK G C+ C GY+ L E
Sbjct: 355 IPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDE 414
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCD---VSG 599
C+ C C+P GS C+ G C C T G +CD+C PG + C CD +
Sbjct: 415 NVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHC 474
Query: 600 SIGSTCDDNGLCHCKSNFDGAKCDTCR 626
G TC +N C C + + G C+ R
Sbjct: 475 QNGGTCHNNVRCLCPAAYTGILCEKLR 501
Score = 73.7 bits (173), Expect = 1e-11
Identities = 57/198 (28%), Positives = 84/198 (42%), Gaps = 31/198 (15%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLH------TGDYCKP-------CNCSG 1881
+ S ++C C+ G C C Y G P + T + C P C C G
Sbjct: 309 DNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368
Query: 1882 NINPQDPGSCDSINGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFG 1936
+ N D +N C+ C +NT G C LC G++ +A + +N C C C+ G
Sbjct: 369 HSNRCS--YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLG 426
Query: 1937 -MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----- 1990
+ D + +G C C+ G G KCD C P G + GC P C +E C +
Sbjct: 427 SIHDRCNGSGFCECKTGTTGPKCDECLP---GNSWHYGCQPNVCD--NELLHCQNGGTCH 481
Query: 1991 DNGQCRCAKGVTGKQCDQ 2008
+N +C C TG C++
Sbjct: 482 NNVRCLCPAAYTGILCEK 499
Score = 67.7 bits (158), Expect = 7e-10
Identities = 50/153 (32%), Positives = 69/153 (45%), Gaps = 26/153 (16%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACP 1818
C+C GHS++C +NT IC++C NT G HCE C GY + A + C+ C C
Sbjct: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC- 422
Query: 1819 MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCN 1878
P + C NGS C C+ G G +C+ C G H G C+P
Sbjct: 423 --NPLGSIHDRC----NGSGF-CECKTGTTGPKCDECLPG-------NSWHYG--CQPNV 466
Query: 1879 CSGN-INPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C ++ Q+ G+C + N CL C G C
Sbjct: 467 CDNELLHCQNGGTCHN-NVRCL-CPAAYTGILC 497
Score = 66.5 bits (155), Expect = 2e-09
Identities = 66/247 (26%), Positives = 95/247 (38%), Gaps = 42/247 (17%)
Query: 1308 ASYNYYISPNET-GLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQC-PCKPNV 1365
A Y Y IS + G C+ + + Y++ C C E NT G C CK N
Sbjct: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--------EHNTTGPDCGKCKKNY 333
Query: 1366 IGR-------------TCSACRTGYYGFPNCRPC--HCPSTAICD--DNGMCI-CPKNVE 1407
GR T + C NC C H + D + +C+ C N
Sbjct: 334 QGRPWSPGSYLPIPKGTANTCIPSISSIGNCE-CFGHSNRCSYIDLLNTVICVSCKHNTR 392
Query: 1408 GENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC 1462
G++C+ C+ F D + C +C CNPLG + ++ C SG C C+ G C
Sbjct: 393 GQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR--CNG-SGFCECKTGTTGPKC 449
Query: 1463 DHCVPGHYAFPDCYQCTCNR---HGTTYDVCDQNTAQCYCKTNVRGQACDTCK-EEYFNL 1518
D C+PG+ C C+ H C N +C C G C+ + EE +
Sbjct: 450 DECLPGNSWHYGCQPNVCDNELLHCQNGGTC-HNNVRCLCPAAYTGILCEKLRCEEAGSC 508
Query: 1519 QDDNPDG 1525
D+ G
Sbjct: 509 GSDSGQG 515
Score = 64.1 bits (149), Expect = 9e-09
Identities = 48/174 (27%), Positives = 67/174 (38%), Gaps = 31/174 (17%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY---------YMQV-LGRERQCV 546
C C+ T + D+ C C+ GP C +C Y Y+ + G C+
Sbjct: 297 CKCNLHATV-CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
Query: 547 PC-----NCDPTGSTSTSCSADGKCN------CLTNFGGAQCDQCSPGYYKYPD------ 589
P NC+ G S CS N C N G C+ C GY++
Sbjct: 356 PSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDE 414
Query: 590 --CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
C+ C C+ GSI C+ +G C CK+ G KCD C + C+ CD
Sbjct: 415 NVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD 468
Score = 58.8 bits (136), Expect = 3e-07
Identities = 57/221 (25%), Positives = 82/221 (37%), Gaps = 46/221 (20%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H T C YD +L+ + C+HNT G +C KC+ Y RP+
Sbjct: 297 CKCNLHATVCVYD----NSKLTCE-------------CEHNTTGPDCGKCKKNYQGRPWS 339
Query: 350 K-RWDELDVCQPCQCDPHFST-GNCE--EESGRC------------ECRPEFQPPDCSSC 393
+ + C P S+ GNCE S RC C+ + C C
Sbjct: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELC 399
Query: 394 AYGYF--------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG--- 442
GYF D C C CN G+ + C + G C CK G C+ C G
Sbjct: 400 RLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGS-GFCECKTGTTGPKCDECLPGNSW 458
Query: 443 YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ 483
+Y + C+ + + C C + Y+G C +
Sbjct: 459 HYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
Score = 52.4 bits (120), Expect = 3e-05
Identities = 38/139 (27%), Positives = 60/139 (43%), Gaps = 23/139 (16%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEYNPFGCEQCNCNLAGTLNSLGACNT--KSGQC 714
C+C+ G C CK Y W+ Y P N + +++S+G C S +C
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP-SISSIGNCECFGHSNRC 373
Query: 715 ------------VCKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGGSIDNNCD 759
CK + + C+ C G++R Q +D C EC C+ GSI + C+
Sbjct: 374 SYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN 433
Query: 760 KTTGQCHCHSRVEGRRCDQ 778
+G C C + G +CD+
Sbjct: 434 -GSGFCECKTGTTGPKCDE 451
Score = 52.0 bits (119), Expect = 4e-05
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 1941 DSTTGTCVCRPGVIGEKCDRCAPDHWGL------------NTGLGCTPC-----NCGIAS 1983
D++ TC C G C +C ++ G T C P NC
Sbjct: 309 DNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368
Query: 1984 ESTQCDD----DNGQC-RCAKGVTGKQCDQCAAGFWNYT------KDGCDHCNCNTGYSV 2032
S +C + C C G+ C+ C G++ ++ C C CN S+
Sbjct: 369 HSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSI 428
Query: 2033 GFMCNATGQCECLPGVIGEKCDRC 2056
CN +G CEC G G KCD C
Sbjct: 429 HDRCNGSGFCECKTGTTGPKCDEC 452
Score = 50.0 bits (114), Expect = 2e-04
Identities = 51/212 (24%), Positives = 79/212 (37%), Gaps = 35/212 (16%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD-PRGVT----- 646
C C++ ++ + C C+ N G C C++ + P P+G
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 647 --ASFAGCGSVPAGELCQ------------CKDRVQGRICNDCKPLYW---NLQEYNPFG 689
+S C C CK +G+ C C+ Y+ + Q +
Sbjct: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG---FYRLQTNDVFGCTEC 746
C +C CN G+++ CN SG C CK +CD+CL G Y Q N V
Sbjct: 417 CIECYCNPLGSIHD--RCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPN-VCDNELL 472
Query: 747 DCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
C GG+ NN +C C + G C++
Sbjct: 473 HCQNGGTCHNNV-----RCLCPAAYTGILCEK 499
Score = 47.6 bits (108), Expect = 8e-04
Identities = 51/193 (26%), Positives = 74/193 (38%), Gaps = 38/193 (19%)
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--------IFSKNCTACI--------CDEFGMADCDS- 1942
+C +NT G C C + G I CI C+ FG ++ S
Sbjct: 316 ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY 375
Query: 1943 ----TTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDD 1991
T CV C+ G+ C+ C ++ L+ C C C + S +C+
Sbjct: 376 IDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG- 434
Query: 1992 NGQCRCAKGVTGKQCDQCAAG-FWNYTKDGCDHCNCNTGY---SVGFMCNATGQCECLPG 2047
+G C C G TG +CD+C G W+Y GC C+ G C+ +C C
Sbjct: 435 SGFCECKTGTTGPKCDECLPGNSWHY---GCQPNVCDNELLHCQNGGTCHNNVRCLCPAA 491
Query: 2048 VIGEKCD--RCPE 2058
G C+ RC E
Sbjct: 492 YTGILCEKLRCEE 504
Score = 39.5 bits (88), Expect = 0.22
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 11/71 (15%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG CE C G++R S C+ C CN D+C+ +G C C T
Sbjct: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN-GSGFC-ECKTGT 444
Query: 1789 IGDHCEFCMSG 1799
G C+ C+ G
Sbjct: 445 TGPKCDECLPG 455
>AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein
protein.
Length = 626
Score = 167 bits (405), Expect = 9e-40
Identities = 147/502 (29%), Positives = 203/502 (40%), Gaps = 73/502 (14%)
Query: 227 IGGRCMCN-GH-ADTCEPADPAGNLNILVC-RCQ-HNTCGPQCNKCCSGFE-QKKWRISQ 281
+ G+C C G+ D C+ P G+ RC HN G QC+ E + ++ +
Sbjct: 37 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHN--GGQCSPTTGACECEPGYKGPR 94
Query: 282 NWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCR 341
+R E + T C D + +S + G C CQ G +CN+
Sbjct: 95 CQERLCPEGLHGPGCTLPCPCDAD---NTISC-----HPVTGAC-TCQPGWSGHHCNESC 145
Query: 342 PTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFD 399
P Y YG D CQ PC C + +C +G C C P F C+ SCA G +
Sbjct: 146 PVGY--YG------DGCQLPCTCQ---NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG 194
Query: 400 YPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKNCECNTVG 457
PNC C+CN GT C+P DG C CK + G C + C G + C N C
Sbjct: 195 -PNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNC-NESCTCAN 248
Query: 458 SVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC 516
+ C + G C+C + G TC C G + + C+C + CD V+G C
Sbjct: 249 GAA--CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADG----CDPVTGHC 302
Query: 517 ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C AG+ G RCD C G + V C+C+ GS S DG C C F G
Sbjct: 303 CCLAGWTGIRCDSTCPPGRW-----GPNCSVSCSCENGGSCSPE---DGSCECAPGFRGP 354
Query: 576 QCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C + C PG+Y + C V S C +G+C C F GA C+ C ++
Sbjct: 355 LCQRICPPGFYGHGCAQPCPLCVHSS--RPCHHISGICECLPGFSGALCNQVCAGGYFGQ 412
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCE 691
+ C+C G + G CQC G+ C+ C P +W P
Sbjct: 413 DCAQLCSCANNGTCSPIDGS--------CQCFPGWIGKDCSQACPPGFW-----GPACFH 459
Query: 692 QCNC-NLAGTLNSLGACNTKSG 712
C+C N A GAC+ G
Sbjct: 460 ACSCHNGASCSAEDGACHCTPG 481
Score = 164 bits (398), Expect = 6e-39
Identities = 124/438 (28%), Positives = 180/438 (41%), Gaps = 62/438 (14%)
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEH 417
Q C C H G C+ +G+C C + C C +G F + + C C+ G
Sbjct: 24 QDCPC--HHG-GQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCH----NGGQ 76
Query: 418 CTPTDGLCPCKYNYAGKSCE--ICEDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKS 474
C+PT G C C+ Y G C+ +C +G + P C C C+ ++S C +TG CTC+
Sbjct: 77 CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTIS--CHPVTGACTCQP 134
Query: 475 KYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLS 532
+SG CN+ C GYY PC C +G + C ++G C C GF G C C +
Sbjct: 135 GWSGHHCNESCPVGYYGDGCQLPCTCQ-NGAD---CHSITGGCTCAPGFMGEVCAVSCAA 190
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPDCL 591
G Y G + C+C+ G+ S DG C C + G C C G + L
Sbjct: 191 GTY----GPNCSSI-CSCNNGGTCSP---VDGSCTCKEGWQGLDCTLPCPSGTWG----L 238
Query: 592 SCNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASF 649
+CN + + G+ C +G C C + G C+ C + + E C+C
Sbjct: 239 NCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD----- 293
Query: 650 AGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN 708
GC V G C C G C+ C P W P NC+++ + + G+C+
Sbjct: 294 -GCDPV-TGHCC-CLAGWTGIRCDSTCPPGRWG-----P------NCSVSCSCENGGSCS 339
Query: 709 TKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
+ G C C C + C GFY GC + C + C +G C C
Sbjct: 340 PEDGSCECAPGFRGPLCQRICPPGFYG------HGCAQ-PCPLCVHSSRPCHHISGICEC 392
Query: 768 HSRVEGRRCDQPIRAHYF 785
G C+Q YF
Sbjct: 393 LPGFSGALCNQVCAGGYF 410
Score = 158 bits (383), Expect = 4e-37
Identities = 126/431 (29%), Positives = 170/431 (39%), Gaps = 65/431 (15%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHC 418
PC CD +T +C +G C C+P + C+ SC GY+ PCTC NG + C
Sbjct: 112 PCPCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ-NGAD---C 166
Query: 419 TPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
G C C + G+ C + C G Y P C + C CN G+ C + G CTCK +
Sbjct: 167 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT----CSPVDGSCTCKEGW 222
Query: 477 SGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGY 534
G C C +G + + C C C + G C C G+ G C+ C G
Sbjct: 223 QGLDCTLPCPSGTWGLNCNESCTCANGAA----CSPIDGSCSCTPGWLGDTCELPCPDGT 278
Query: 535 YMQVLGRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPDC-L 591
+ C + CDP G C CL + G +CD C PG + P+C +
Sbjct: 279 FGLNCSEHCDCSHADGCDPV---------TGHCCCLAGWTGIRCDSTCPPGRWG-PNCSV 328
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFA 650
SC+C+ GS ++G C C F G C C FY + + C P V +S
Sbjct: 329 SCSCENGGSCSP---EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPC---PLCVHSS-R 381
Query: 651 GCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQ-CNCNLAGTLNSLGACN 708
C + +C+C G +CN C Y+ C Q C+C GT C+
Sbjct: 382 PCHHISG--ICECLPGFSGALCNQVCAGGYFGQD------CAQLCSCANNGT------CS 427
Query: 709 TKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G C C + C Q C GF+ C C G S C G CHC
Sbjct: 428 PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHA-----CSCHNGAS----CSAEDGACHC 478
Query: 768 HSRVEGRRCDQ 778
G C Q
Sbjct: 479 TPGWTGLFCTQ 489
Score = 132 bits (320), Expect = 2e-29
Identities = 110/333 (33%), Positives = 137/333 (41%), Gaps = 66/333 (19%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQCNGHSD-QCDVNTGICLNCADNTIGDH 1792
C+C Y+G C++ C EG + G +PC C+ + C TG C C G H
Sbjct: 84 CECEPGYKGPRCQERLCPEGLHG--PGCTLPCPCDADNTISCHPVTGAC-TCQPGWSGHH 140
Query: 1793 C-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C E C GY+GD C +P N A C G C C PG+ G
Sbjct: 141 CNESCPVGYYGDG------------CQLPCTCQNGA-DCHSITGG----CTCAPGFMGEV 183
Query: 1852 CEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C CAAG YG P NCS + + G+C ++G C C G C
Sbjct: 184 CAVSCAAGTYG--------------P-NCSSICSCNNGGTCSPVDGSCT-CKEGWQGLDC 227
Query: 1911 NL-CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGL 1968
L C G +G NC +C C G A C G+C C PG +G+ C+ PD
Sbjct: 228 TLPCPSGTWG-----LNCNESCTCAN-GAA-CSPIDGSCSCTPGWLGDTCELPCPDG--- 277
Query: 1969 NTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCD-HCN 2025
GL C+ C+C S + CD G C C G TG +CD C G W C C+
Sbjct: 278 TFGLNCSEHCDC---SHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG---PNCSVSCS 331
Query: 2026 CNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
C G G G CEC PG G C R CP
Sbjct: 332 CENG---GSCSPEDGSCECAPGFRGPLCQRICP 361
Score = 128 bits (310), Expect = 3e-28
Identities = 115/375 (30%), Positives = 150/375 (40%), Gaps = 57/375 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C + G C E C G+Y G +PC C +D C TG C CA +G+ C
Sbjct: 130 CTCQPGWSGHHCNESCPVGYYG--DGCQLPCTCQNGAD-CHSITGGC-TCAPGFMGEVCA 185
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCN--CQPGYGGAR 1851
C +G +G P IC+C + SC E + C C G G
Sbjct: 186 VSCAAGTYG------PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLN 239
Query: 1852 CEY---CAAGYYGIPED-----TDLHTGDYCK-PC-------NCSGNINPQDPGSCDSIN 1895
C CA G P D T GD C+ PC NCS + + CD +
Sbjct: 240 CNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVT 299
Query: 1896 GDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGV 1953
G C C+ G C+ C PG +G NC+ +C C+ G C G+C C PG
Sbjct: 300 GHCC-CLAGWTGIRCDSTCPPGRWGP-----NCSVSCSCENGG--SCSPEDGSCECAPGF 351
Query: 1954 IGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAA 2011
G C R P + G GC PC + S S C +G C C G +G C+Q CA
Sbjct: 352 RGPLCQRICPPGF---YGHGCAQPCPLCVHS-SRPCHHISGICECLPGFSGALCNQVCAG 407
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR-CPER-WVLIPQEGCL 2069
G+ + +D C+C G G C+C PG IG+ C + CP W C
Sbjct: 408 GY--FGQDCAQLCSCANN---GTCSPIDGSCQCFPGWIGKDCSQACPPGFW----GPACF 458
Query: 2070 ECDSCTDALIFSVED 2084
SC + S ED
Sbjct: 459 HACSCHNGASCSAED 473
Score = 128 bits (308), Expect = 5e-28
Identities = 105/348 (30%), Positives = 139/348 (39%), Gaps = 55/348 (15%)
Query: 439 CEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKP 496
C G + C ++C C+ G CD +TG C C + Y G C +C G + + +
Sbjct: 13 CPPGTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQR 68
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C+C G C +G C C+ G+ GPRC + L + G C PC+ D T
Sbjct: 69 CDCHNGGQ----CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC-PCDADNT--- 120
Query: 557 STSC-SADGKCNCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCHC 613
SC G C C + G C++ C GYY L C C G+ C G C C
Sbjct: 121 -ISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTC----QNGADCHSITGGCTC 175
Query: 614 KSNFDGAKCD-TCREQFYNYPACEE-CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
F G C +C Y P C C+C+ G T S P C CK+ QG
Sbjct: 176 APGFMGEVCAVSCAAGTYG-PNCSSICSCN-NGGTCS-------PVDGSCTCKEGWQGLD 226
Query: 672 CN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD-QCL 729
C C W L NCN + T + AC+ G C C C+ C
Sbjct: 227 CTLPCPSGTWGL-----------NCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCP 275
Query: 730 DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
DG + L ++ CDC S + CD TG C C + G RCD
Sbjct: 276 DGTFGLNCSE-----HCDC----SHADGCDPVTGHCCCLAGWTGIRCD 314
Score = 109 bits (261), Expect = 2e-22
Identities = 109/390 (27%), Positives = 150/390 (38%), Gaps = 57/390 (14%)
Query: 227 IGGRCMC----NGHA--DTCEPADPAGNLNILVCRCQHNTCGPQCNK------CCSGFEQ 274
+ G C C +GH ++C P G+ L C CQ+ G C+ C GF
Sbjct: 126 VTGACTCQPGWSGHHCNESC-PVGYYGDGCQLPCTCQN---GADCHSITGGCTCAPGFMG 181
Query: 275 KKWRISQNWDRF--SCEP-CNCHNHTTECTYDPEIDEKR--LSLDINGRYEGGGKCLNCQ 329
+ +S + +C C+C+N T D K LD G LNC
Sbjct: 182 EVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCN 241
Query: 330 HNTEGINCNKCRPTYYRPYGKRWDELDVCQ-PC-------QCDPHFSTGN---CEEESGR 378
+ N C P D C+ PC C H + C+ +G
Sbjct: 242 ESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGH 301
Query: 379 CECRPEFQPPDC-SSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC 436
C C + C S+C G + PNC C+C G+ C+P DG C C + G C
Sbjct: 302 CCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCENGGS----CSPEDGSCECAPGFRGPLC 356
Query: 437 E-ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTC 494
+ IC G+Y C C S C ++G C C +SG CNQ C GY+
Sbjct: 357 QRICPPGFYGHGCAQ-PCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCA 415
Query: 495 KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPT 553
+ C+C +GT C + G C C G+ G C Q C G++ C+C
Sbjct: 416 QLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHA-----CSCH-- 464
Query: 554 GSTSTSCSA-DGKCNCLTNFGGAQCDQCSP 582
SCSA DG C+C + G C Q P
Sbjct: 465 --NGASCSAEDGACHCTPGWTGLFCTQRKP 492
Score = 97.5 bits (232), Expect = 8e-19
Identities = 87/310 (28%), Positives = 117/310 (37%), Gaps = 50/310 (16%)
Query: 478 GRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYY 535
G C Q C G + + C C G CD V+GQC C AG+ G RC ++C G +
Sbjct: 6 GAVCAQPCPPGTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFGSF 61
Query: 536 MQVLGRERQCVP-CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDC-L 591
QC C+C G S + G C C + G +C + C G + P C L
Sbjct: 62 ------GFQCSQRCDCHNGGQCSPT---TGACECEPGYKGPRCQERLCPEGLHG-PGCTL 111
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFA 650
C CD +I S G C C+ + G C ++C +Y C C + A
Sbjct: 112 PCPCDADNTI-SCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ------NGA 164
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
C S+ G C C G +C + Y P C+CN GT C+
Sbjct: 165 DCHSITGG--CTCAPGFMGEVC----AVSCAAGTYGPNCSSICSCNNGGT------CSPV 212
Query: 711 SGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHS 769
G C CK+ C C G + L N+ C C G + C G C C
Sbjct: 213 DGSCTCKEGWQGLDCTLPCPSGTWGLNCNE-----SCTCANGAA----CSPIDGSCSCTP 263
Query: 770 RVEGRRCDQP 779
G C+ P
Sbjct: 264 GWLGDTCELP 273
Score = 97.1 bits (231), Expect = 1e-18
Identities = 88/279 (31%), Positives = 120/279 (43%), Gaps = 54/279 (19%)
Query: 1736 CQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C + G +CE C +G + L C C+ H+D CD TG C C G C+
Sbjct: 259 CSCTPGWLGDTCELPCPDGTFGLNCS--EHCDCS-HADGCDPVTGHCC-CLAGWTGIRCD 314
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G G P + C+C N SC E+GS C C PG+ G C+
Sbjct: 315 STCPPGRWG------PNCSVSCSC------ENGG-SCS-PEDGS---CECAPGFRGPLCQ 357
Query: 1854 -YCAAGYYGIPEDTDLHTGDYCKPCN-CSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
C G+YG H +PC C + P C I+G C +C+ +GA CN
Sbjct: 358 RICPPGFYG-------H--GCAQPCPLCVHSSRP-----CHHISGIC-ECLPGFSGALCN 402
Query: 1912 -LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLN 1969
+CA G++G ++C A +C C G+C C PG IG+ C + C P WG
Sbjct: 403 QVCAGGYFG-----QDC-AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPA 456
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ 2008
C+ C+ G C ++G C C G TG C Q
Sbjct: 457 CFHACS-CHNG-----ASCSAEDGACHCTPGWTGLFCTQ 489
Score = 95.1 bits (226), Expect = 4e-18
Identities = 82/269 (30%), Positives = 97/269 (36%), Gaps = 46/269 (17%)
Query: 1814 ICACPMPYPS--NNFALSCDLSENGSLI----SCNCQPGYGGARC-EYCAAGYYGIPEDT 1866
+CA P P + N + C G C+C GY G RC E C G +G
Sbjct: 8 VCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGF---- 63
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDAIFS 1924
CS + + G C G C +C G C LC G +G
Sbjct: 64 -----------QCSQRCDCHNGGQCSPTTGAC-ECEPGYKGPRCQERLCPEGLHGPG--- 108
Query: 1925 KNCTA-CICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGC-TPCNCGIA 1982
CT C CD C TG C C+PG G C+ P + G GC PC C
Sbjct: 109 --CTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGY---YGDGCQLPCTC--- 160
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ 2041
C G C CA G G+ C CAAG Y + C+CN G G G
Sbjct: 161 QNGADCHSITGGCTCAPGFMGEVCAVSCAAG--TYGPNCSSICSCNNG---GTCSPVDGS 215
Query: 2042 CECLPGVIGEKCD-RCPE-RWVLIPQEGC 2068
C C G G C CP W L E C
Sbjct: 216 CTCKEGWQGLDCTLPCPSGTWGLNCNESC 244
Score = 81.0 bits (191), Expect = 7e-14
Identities = 71/233 (30%), Positives = 96/233 (41%), Gaps = 47/233 (20%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHC 1793
C C + G+ C+ C G R V C C NG S C G C CA G C
Sbjct: 302 CCCLAGWTGIRCDSTCPPG--RWGPNCSVSCSCENGGS--CSPEDGSC-ECAPGFRGPLC 356
Query: 1794 E-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G++G G + C +C P ++ + C+ C PG+ GA C
Sbjct: 357 QRICPPGFYGH---GCAQPCPLCV-HSSRPCHHISGICE-----------CLPGFSGALC 401
Query: 1853 -EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
+ CA GY+G D + C+C+ N G+C I+G C +C G C+
Sbjct: 402 NQVCAGGYFG---------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDCS 445
Query: 1912 -LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C PGF+G A F AC C A C + G C C PG G C + P
Sbjct: 446 QACPPGFWGPACFH----ACSCHNG--ASCSAEDGACHCTPGWTGLFCTQRKP 492
Score = 78.6 bits (185), Expect = 4e-13
Identities = 55/185 (29%), Positives = 71/185 (38%), Gaps = 23/185 (12%)
Query: 1333 YNSGAR-PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCP 1389
Y G + PC C +C++ G C C P +G C+ +C G YG PNC C C
Sbjct: 150 YGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCN 204
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADS 1448
+ C +G C C + +G +C P G NCN N C
Sbjct: 205 NGGTCSPVDGSCTCKEGWQGLDCTLPCP--------SGTWGLNCNESCTCANGAACSPID 256
Query: 1449 GKCACRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
G C+C G C+ C G + C C+ H D CD T C C G
Sbjct: 257 GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS-HA---DGCDPVTGHCCCLAGWTGIR 312
Query: 1508 CD-TC 1511
CD TC
Sbjct: 313 CDSTC 317
Score = 73.7 bits (173), Expect = 1e-11
Identities = 56/195 (28%), Positives = 71/195 (36%), Gaps = 22/195 (11%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD- 1396
PC CD + C+ G C C+P G C+ +C GYYG PC C + A C
Sbjct: 112 PCPCD--ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI 169
Query: 1397 NGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACR 1454
G C C GE C C T+ C C+CN G C G C C+
Sbjct: 170 TGGCTCAPGFMGEVCAVSCAAGTYG----PNCSSICSCNNGGT------CSPVDGSCTCK 219
Query: 1455 ENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCK 1512
E +G C C G + CTC +G C C C G C+ C
Sbjct: 220 EGWQGLDCTLPCPSGTWGLNCNESCTC-ANGA---ACSPIDGSCSCTPGWLGDTCELPCP 275
Query: 1513 EEYFNLQDDNPDGCT 1527
+ F L C+
Sbjct: 276 DGTFGLNCSEHCDCS 290
Score = 68.1 bits (159), Expect = 6e-10
Identities = 48/162 (29%), Positives = 61/162 (37%), Gaps = 17/162 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCR-PCHCPSTAICD-DNGMCICPKNVEG 1408
C+ G C C G C S C G +G PNC C C + C ++G C C G
Sbjct: 295 CDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCENGGSCSPEDGSCECAPGFRG 353
Query: 1409 ENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C R C P + + C C V + C SG C C G +C+
Sbjct: 354 PLCQRICPPGFYGHGCAQPCPLC-------VHSSRPCHHISGICECLPGFSGALCNQVCA 406
Query: 1468 GHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G Y DC Q C+C +GT C C C G+ C
Sbjct: 407 GGYFGQDCAQLCSCANNGT----CSPIDGSCQCFPGWIGKDC 444
Score = 67.3 bits (157), Expect = 1e-09
Identities = 48/171 (28%), Positives = 58/171 (33%), Gaps = 18/171 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G C C P +G TC C G +G C C CD G C C G
Sbjct: 252 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 311
Query: 1410 NCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CV 1466
CD C P + C C+C G C + G C C RG +C C
Sbjct: 312 RCDSTCPPGRWG----PNCSVSCSCENGG------SCSPEDGSCECAPGFRGPLCQRICP 361
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYF 1516
PG Y C H + C + C C G C+ C YF
Sbjct: 362 PGFYGHGCAQPCPLCVHSSR--PCHHISGICECLPGFSGALCNQVCAGGYF 410
Score = 64.5 bits (150), Expect = 7e-09
Identities = 45/163 (27%), Positives = 63/163 (38%), Gaps = 16/163 (9%)
Query: 1351 ECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDN-GMCICPKNVEG 1408
+C+ GQC C +G C C G +GF + C C + C G C C +G
Sbjct: 33 QCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACECEPGYKG 92
Query: 1409 ENC-DRCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHC 1465
C +R P + GC C C+ N + C +G C C+ G C + C
Sbjct: 93 PRCQERLCPEGLHGP---GCTLPCPCD----ADNTISCHPVTGACTCQPGWSGHHCNESC 145
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+Y CTC ++G C T C C G+ C
Sbjct: 146 PVGYYGDGCQLPCTC-QNGAD---CHSITGGCTCAPGFMGEVC 184
Score = 57.6 bits (133), Expect = 8e-07
Identities = 47/175 (26%), Positives = 65/175 (37%), Gaps = 23/175 (13%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCH-CP-STAICDD 1396
C C+ GS C+ G C C P G C C G+YG +PC C S+ C
Sbjct: 330 CSCENGGS----CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHH 385
Query: 1397 -NGMCICPKNVEGENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
+G+C C G C++ C F D + C +C N C G C C
Sbjct: 386 ISGICECLPGFSGALCNQVCAGGYFGQDCAQLC---SC------ANNGTCSPIDGSCQCF 436
Query: 1455 ENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+ C P + P C+ C+C+ + C C+C G C
Sbjct: 437 PGWIGKDCSQACPPGFWGPACFHACSCHNGAS----CSAEDGACHCTPGWTGLFC 487
Score = 55.2 bits (127), Expect = 4e-06
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 37/179 (20%)
Query: 1360 PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGENC-DRCKPY 1417
PC P G+ CS +C PCH CD G C C G+ C + C
Sbjct: 12 PCPPGTFGQNCS---------QDC-PCH--HGGQCDHVTGQCHCTAGYMGDRCQEECPFG 59
Query: 1418 TFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH--CVPGHYAFPDC 1475
+F F + C DC+ N QC +G C C +G C C G + P C
Sbjct: 60 SFGFQCSQRC-DCH--------NGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG-PGC 109
Query: 1476 -YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYFNLQDDNPDGC-TKCFC 1531
C C+ T C T C C+ G C ++C Y+ DGC C C
Sbjct: 110 TLPCPCDADNTI--SCHPVTGACTCQPGWSGHHCNESCPVGYYG------DGCQLPCTC 160
Score = 52.0 bits (119), Expect = 4e-05
Identities = 40/140 (28%), Positives = 54/140 (38%), Gaps = 17/140 (12%)
Query: 1333 YNSG-ARPC-LCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCP 1389
Y G A+PC LC + C+ G C C P G C+ C GY+G + C C
Sbjct: 365 YGHGCAQPCPLCVH---SSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCA 421
Query: 1390 STAICDD-NGMCICPKNVEGENCDRCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEAD 1447
+ C +G C C G++C + P F C C+C+ N C A+
Sbjct: 422 NNGTCSPIDGSCQCFPGWIGKDCSQACPPGF---WGPACFHACSCH------NGASCSAE 472
Query: 1448 SGKCACRENVRGRVCDHCVP 1467
G C C G C P
Sbjct: 473 DGACHCTPGWTGLFCTQRKP 492
Score = 50.4 bits (115), Expect = 1e-04
Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAIC 1394
A+ C C G+ C+ G C C P IG+ CS AC G++G P C C C + A C
Sbjct: 415 AQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWG-PACFHACSCHNGASC 469
Query: 1395 D-DNGMCICPKNVEGENCDRCKPY 1417
++G C C G C + KP+
Sbjct: 470 SAEDGACHCTPGWTGLFCTQRKPH 493
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 165 bits (400), Expect = 4e-39
Identities = 163/564 (28%), Positives = 215/564 (38%), Gaps = 89/564 (15%)
Query: 254 CRCQHNTCGPQCNKCC-SGFEQKKWRIS---QNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
C C GP C + C +G R S QN +C+P + H E +++
Sbjct: 1093 CHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGG--TCDPVSGHCACPEGWAGLACEKE 1150
Query: 310 RLSLDINGRYEGGGKCLN---CQHNTEGINC------NKCRPTYYRPYGKRWDELDVCQP 360
L D+ G CLN C +T C +KC+ P + W Q
Sbjct: 1151 CLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQS----PCLRGWFGEACAQR 1206
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
C C P C +G C C P F C +C G F + C C E C
Sbjct: 1207 CSCPP---AAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCP---GENPACH 1260
Query: 420 PTDGLCPCKYNYAGKSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYS 477
P G C C Y G SC+ C G Y P C+ C C GS CD TG C C + +
Sbjct: 1261 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGS----CDAATGACRCPTGFL 1316
Query: 478 GRTCN-QCQAGYYNYPTCKP-CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ-CLSGY 534
G CN C G + P C C C + + CD V+G C+C G G RC++ C
Sbjct: 1317 GTDCNLTCPQGRFG-PNCTHVCGCG----QGAACDPVTGTCLCPPGRAGVRCERGCPQNR 1371
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPDCLSC 593
+ +G E C +C G S +G C+C + G C+ C PG Y L C
Sbjct: 1372 FG--VGCEHTC---SCRNGGLCHAS---NGSCSCGLGWTGRHCELACPPGRYGAACHLEC 1423
Query: 594 NCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNYPACEECNCDPRGVTASFAG 651
+C + STC+ G C C F G C+ C F+ C C G
Sbjct: 1424 SCHNN----STCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQH--------G 1471
Query: 652 CGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQ-CNCNLAGTLNSLGACNT 709
P C C G C C+P + E GC Q C+C+ G C+
Sbjct: 1472 APCDPISGRCLCPAGFHGHFCERGCEP--GSFGE----GCHQRCDCD-GGA-----PCDP 1519
Query: 710 KSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCH 768
+G C+C C+ C G + CT CD GG D CD +GQCHC
Sbjct: 1520 VTGLCLCPPGRSGATCNLDCRRGQFGPS------CT-LHCDCGGGAD--CDPVSGQCHCV 1570
Query: 769 SRVEGRRCDQ--PIRAHYFPTLHQ 790
G C + P+R P+L Q
Sbjct: 1571 DGYMGPTCREGGPLRLPENPSLAQ 1594
Score = 160 bits (389), Expect = 8e-38
Identities = 124/434 (28%), Positives = 173/434 (39%), Gaps = 60/434 (13%)
Query: 363 CDPHFSTGN--CEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCT 419
C S G C +G+C C P DC + C G + + C + C
Sbjct: 815 CSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAAR---CD 871
Query: 420 PTDGLCPCKYNYAGKSCE-ICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYS 477
P G C C + G C+ +C G+Y P C+ C C G C TG C+C ++
Sbjct: 872 PETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGH----CHPATGHCSCAPGWT 927
Query: 478 GRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYY 535
G +C + C G++ PCNC CD +SG C+C+AG+ GPRC+ QC G++
Sbjct: 928 GFSCQRACDTGHWGPDCSHPCNCSAGHGS---CDAISGLCLCEAGYVGPRCEQQCPQGHF 984
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS-CN 594
G E+ C C G+ S G C C + G C+ P + DC S CN
Sbjct: 985 GP--GCEQL---CQCQ-HGAACDHVS--GACTCPAGWRGTFCEHACPAGFFGLDCRSACN 1036
Query: 595 CDVSGSIGSTCDD-NGLCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFAGC 652
C + G+ CD NG C C + G +C +TC Y + + C C F G
Sbjct: 1037 C----TAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACAC--------FNGA 1084
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG 712
P C C G C LQ P G NC + + G C+ SG
Sbjct: 1085 SCDPVHGQCHCAPGWMGPSC---------LQAC-PAGLYGDNCRHSCLCQNGGTCDPVSG 1134
Query: 713 QCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRV 771
C C + C+ +CL R GC + G + CD TG+C C +
Sbjct: 1135 HCACPEGWAGLACEKECLPRDVRA------GCRHSGGCLNGGL---CDPHTGRCLCPAGW 1185
Query: 772 EGRRCDQPIRAHYF 785
G +C P +F
Sbjct: 1186 TGDKCQSPCLRGWF 1199
Score = 148 bits (359), Expect = 3e-34
Identities = 150/571 (26%), Positives = 205/571 (35%), Gaps = 94/571 (16%)
Query: 226 SIGGRCMCN-GHADT-CEPADPAGNLNI---LVCRCQHNTCGPQCNKCCSGFEQKKWRIS 280
+I G C+C G+ CE P G+ +C+CQH + C+
Sbjct: 959 AISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACT--------CP 1010
Query: 281 QNWDRFSCE-PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
W CE C +C +NG CL C G C +
Sbjct: 1011 AGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNG------SCL-CPAGRRGPRCAE 1063
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDC-SSCAYGYF 398
P + YG + Q C C F+ +C+ G+C C P + P C +C G +
Sbjct: 1064 TCPAH--TYGH-----NCSQACAC---FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLY 1113
Query: 399 DYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-CEDGYYSPECKNCECNTV 456
NC+ C C GT C P G C C +AG +CE C C++
Sbjct: 1114 G-DNCRHSCLCQNGGT----CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLN 1168
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ 515
G + CD TG C C + ++G C C G++ + C+C + C V+G
Sbjct: 1169 GGL---CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAA----CHHVTGA 1221
Query: 516 CICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGG 574
C C GF G C+Q C G + + + QC G A G C+C + G
Sbjct: 1222 CRCPPGFTGSGCEQACPPGSFGEDCAQMCQC-------PGENPACHPATGTCSCAAGYHG 1274
Query: 575 AQCDQ-CSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFY 630
C Q C PG Y P C C C GS CD G C C + F G C+ TC + +
Sbjct: 1275 PSCQQRCPPGRYG-PGCEQLCGCLNGGS----CDAATGACRCPTGFLGTDCNLTCPQGRF 1329
Query: 631 NYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGC 690
C C G P C C G C P Q GC
Sbjct: 1330 GPNCTHVCGCGQ--------GAACDPVTGTCLCPPGRAGVRCERGCP-----QNRFGVGC 1376
Query: 691 EQ-CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTECDC 748
E C+C G C+ +G C C R C+ C G Y + EC C
Sbjct: 1377 EHTCSCRNGGL------CHASNGSCSCGLGWTGRHCELACPPGRYGAACH-----LECSC 1425
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
++ C+ TG C C G+ C+ P
Sbjct: 1426 HN----NSTCEPATGTCRCGPGFYGQACEHP 1452
Score = 145 bits (352), Expect = 2e-33
Identities = 138/485 (28%), Positives = 185/485 (38%), Gaps = 83/485 (17%)
Query: 322 GGKCL------NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEE 374
GG CL +C G+ CN+ P +GK C C C + G C+
Sbjct: 605 GGTCLLGLDGCDCPEGWTGLICNETCPP--DTFGKN------CSFSCSCQ---NGGTCDS 653
Query: 375 ESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
+G C C P +C C GY+ K C C G C G C C G
Sbjct: 654 VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRG----RCHRLYGACLCDPGLYG 709
Query: 434 KSCEI-CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNY 491
+ C + C + P C EC V + CDK G C+CK+ + G C +C+ GY+
Sbjct: 710 RFCHLTCPPWAFGPGCSE-ECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGP 768
Query: 492 PTCKPCNCDTSGTEPSICDDVSGQC--ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPC 548
+ C C CD VSG+C C AGF G C Q C G + C
Sbjct: 769 GCWQACTCPVG----VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGA 824
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPDCLSCN--CDVSGSIGSTC 605
C G T G+C C G C+ C G + L C C
Sbjct: 825 PCH--GVT-------GQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHAARCD 871
Query: 606 DDNGLCHCKSNFDGAKC-DTCREQFYNYPACE-ECNCDPRGVTASFAGCGSVPAGELCQC 663
+ G C C F G++C D C +Y P+C+ C+C A+ C PA C C
Sbjct: 872 PETGACLCLPGFVGSRCQDVCPAGWYG-PSCQTRCSC------ANDGHCH--PATGHCSC 922
Query: 664 KDRVQGRIC-NDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG 721
G C C +W P CNC+ AG G+C+ SG C+C+ +VG
Sbjct: 923 APGWTGFSCQRACDTGHW-----GPDCSHPCNCS-AGH----GSCDAISGLCLCEAGYVG 972
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
R QC G + GC + C C G + CD +G C C + G C+
Sbjct: 973 PRCEQQCPQGHFGP------GCEQLCQCQHGAA----CDHVSGACTCPAGWRGTFCEHAC 1022
Query: 781 RAHYF 785
A +F
Sbjct: 1023 PAGFF 1027
Score = 132 bits (319), Expect = 2e-29
Identities = 112/346 (32%), Positives = 142/346 (41%), Gaps = 51/346 (14%)
Query: 1736 CQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C CP + GL+CE +C R C G CD +TG CL C GD C+
Sbjct: 1136 CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGG---LCDPHTGRCL-CPAGWTGDKCQ 1191
Query: 1795 F-CMSGYHGDATV---GTPRDCLI------CACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
C+ G+ G+A P C CP + + +C G + CQ
Sbjct: 1192 SPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQ 1251
Query: 1845 -PGYGGA------RCEYCAAGYYGIPEDTDLHTGDYCKPCN-CSGNINPQDPGSCDSING 1896
PG A C CAAGY+G G Y C G +N GSCD+ G
Sbjct: 1252 CPGENPACHPATGTCS-CAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNG---GSCDAATG 1307
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIG 1955
C +C G CNL P F NCT C C + G A CD TGTC+C PG G
Sbjct: 1308 AC-RCPTGFLGTDCNLTCP----QGRFGPNCTHVCGCGQ-GAA-CDPVTGTCLCPPGRAG 1360
Query: 1956 EKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
+C+R P + G+GC C+C C NG C C G TG+ C+ C G
Sbjct: 1361 VRCERGCPQN---RFGVGCEHTCSC---RNGGLCHASNGSCSCGLGWTGRHCELACPPG- 1413
Query: 2014 WNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDR-CP 2057
Y C+C+ + C ATG C C PG G+ C+ CP
Sbjct: 1414 -RYGAACHLECSCHNNST----CEPATGTCRCGPGFYGQACEHPCP 1454
Score = 123 bits (297), Expect = 1e-26
Identities = 104/350 (29%), Positives = 140/350 (40%), Gaps = 65/350 (18%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C + G SC++ C GH+ PC C+ CD +G+CL C +G CE
Sbjct: 920 CSCAPGWTGFSCQRACDTGHWGPDCSH--PCNCSAGHGSCDAISGLCL-CEAGYVGPRCE 976
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G+ G P +C C +CD +C C G+ G CE
Sbjct: 977 QQCPQGHFG------PGCEQLCQC-------QHGAACDHVSG----ACTCPAGWRGTFCE 1019
Query: 1854 Y-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ C AG++G+ D CNC+ +CD++NG CL C G C
Sbjct: 1020 HACPAGFFGL---------DCRSACNCTAG------AACDAVNGSCL-CPAGRRGPRCAE 1063
Query: 1913 CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLNT 1970
P + NC+ AC C F A CD G C C PG +G C C +G N
Sbjct: 1064 TCPAH----TYGHNCSQACAC--FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNC 1117
Query: 1971 GLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCDHCNCNTG 2029
C N G CD +G C C +G G C+ +C + GC H + G
Sbjct: 1118 RHSCLCQNGG------TCDPVSGHCACPEGWAGLACEKECLP---RDVRAGCRH---SGG 1165
Query: 2030 YSVGFMCNA-TGQCECLPGVIGEKCDR-CPERWVLIPQEGCLECDSCTDA 2077
G +C+ TG+C C G G+KC C W E C + SC A
Sbjct: 1166 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWF---GEACAQRCSCPPA 1212
Score = 113 bits (273), Expect = 9e-24
Identities = 96/332 (28%), Positives = 130/332 (39%), Gaps = 60/332 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C G C + G CQC H+ CD G C +C G+ C+
Sbjct: 701 CLCDPGLYGRFCHLTCPP-WAFGPGCSEECQCVQPHTQSCDKRDGSC-SCKAGFRGERCQ 758
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC- 1852
C GY G P C CP+ ++CD S +G C G+ G C
Sbjct: 759 AECELGYFG------PGCWQACTCPV-------GVACD-SVSGEC-GKRCPAGFQGEDCG 803
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ C G +G+ + C+C G C + G C +C G C
Sbjct: 804 QECPVGTFGV---------NCSSSCSCGG-------APCHGVTGQC-RCPPGRTGEDCEA 846
Query: 1913 -CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
C G +G + C AC A CD TG C+C PG +G +C P W G
Sbjct: 847 DCPEGRWGLGC-QEICPACQ----HAARCDPETGACLCLPGFVGSRCQDVCPAGW---YG 898
Query: 1972 LGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDH-CNCNT 2028
C T C+C + C G C CA G TG C + C G W C H CNC+
Sbjct: 899 PSCQTRCSC---ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG---PDCSHPCNCSA 952
Query: 2029 GYSVGFMCNA-TGQCECLPGVIGEKCD-RCPE 2058
G+ C+A +G C C G +G +C+ +CP+
Sbjct: 953 GHG---SCDAISGLCLCEAGYVGPRCEQQCPQ 981
Score = 113 bits (271), Expect = 2e-23
Identities = 107/350 (30%), Positives = 130/350 (37%), Gaps = 55/350 (15%)
Query: 1733 VEECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
++ C CP + GL C E C + F CQ G CD TG C C G
Sbjct: 612 LDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG---TCDSVTGAC-RCPPGVSGT 667
Query: 1792 HCE-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
+CE C GY+G R CA A CD G C P G
Sbjct: 668 NCEDGCPKGYYGKHC----RKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP 723
Query: 1851 RCEYCAAGYYGIPEDTDLHTGD-YCKP------CNCSGNINPQDPG-----------SCD 1892
C + D G CK C + PG +CD
Sbjct: 724 GCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACD 783
Query: 1893 SINGDCLK-CVNNTAGAACNL-CAPGFYGDAIFSKNC-TACICDEFGMADCDSTTGTCVC 1949
S++G+C K C G C C G +G NC ++C C G A C TG C C
Sbjct: 784 SVSGECGKRCPAGFQGEDCGQECPVGTFG-----VNCSSSCSC---GGAPCHGVTGQCRC 835
Query: 1950 RPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC-D 2007
PG GE C+ C W GLGC C + +CD + G C C G G +C D
Sbjct: 836 PPGRTGEDCEADCPEGRW----GLGCQEI-CPACQHAARCDPETGACLCLPGFVGSRCQD 890
Query: 2008 QCAAGFWNYTKDGCDHCNC-NTGYSVGFMCN-ATGQCECLPGVIGEKCDR 2055
C AG W Y C+C N G+ C+ ATG C C PG G C R
Sbjct: 891 VCPAG-W-YGPSCQTRCSCANDGH-----CHPATGHCSCAPGWTGFSCQR 933
Score = 110 bits (265), Expect = 8e-23
Identities = 104/328 (31%), Positives = 132/328 (40%), Gaps = 66/328 (20%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHC 1793
C C Y G SC+Q C G Y G C C NG S CD TG C C +G C
Sbjct: 1266 CSCAAGYHGPSCQQRCPPGRYG--PGCEQLCGCLNGGS--CDAATGAC-RCPTGFLGTDC 1320
Query: 1794 EF-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C G G P +C C +CD +C C PG G RC
Sbjct: 1321 NLTCPQGRFG------PNCTHVCGCGQ-------GAACDPVTG----TCLCPPGRAGVRC 1363
Query: 1853 EY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN 1911
E C +G+ + HT C+C ++ G C + NG C C G C
Sbjct: 1364 ERGCPQNRFGVGCE---HT------CSC------RNGGLCHASNGSC-SCGLGWTGRHCE 1407
Query: 1912 L-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
L C PG YG A + C C + C+ TGTC C PG G+ C+ P G +
Sbjct: 1408 LACPPGRYGAACHLE----CSCHN--NSTCEPATGTCRCGPGFYGQACEHPCPP--GFH- 1458
Query: 1971 GLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGC-DHCNCN 2027
G GC C C CD +G+C C G G C++ C G + +GC C+C+
Sbjct: 1459 GAGCQGLCWC---QHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFG---EGCHQRCDCD 1512
Query: 2028 TGYSVGFMCN-ATGQCECLPGVIGEKCD 2054
G C+ TG C C PG G C+
Sbjct: 1513 GGAP----CDPVTGLCLCPPGRSGATCN 1536
Score = 102 bits (244), Expect = 3e-20
Identities = 111/367 (30%), Positives = 145/367 (39%), Gaps = 61/367 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
E QCP+ + G CEQ CQC H CD +G C C G CE
Sbjct: 976 EQQCPQGHFGPGCEQL--------------CQCQ-HGAACDHVSGAC-TCPAGWRGTFCE 1019
Query: 1795 F-CMSGYHG-------DATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
C +G+ G + T G D + C CP A +C G S C
Sbjct: 1020 HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQAC- 1078
Query: 1845 PGYGGARCE------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
+ GA C+ +CA G+ G G Y NC + Q+ G+CD ++G C
Sbjct: 1079 ACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGD--NCRHSCLCQNGGTCDPVSGHC 1136
Query: 1899 LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
C AG AC C P ++ C+ G+ CD TG C+C G G+K
Sbjct: 1137 -ACPEGWAGLACEKECLPRDVRAG--CRHSGGCL--NGGL--CDPHTGRCLCPAGWTGDK 1189
Query: 1958 CDRCAPDHWGLNTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWN 2015
C W G C C+C A+ C G CRC G TG C+Q C G +
Sbjct: 1190 CQSPCLRGW---FGEACAQRCSCPPAA---ACHHVTGACRCPPGFTGSGCEQACPPG--S 1241
Query: 2016 YTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKC-DRCPE-RWVLIPQE--GCLE 2070
+ +D C C G + C+ ATG C C G G C RCP R+ ++ GCL
Sbjct: 1242 FGEDCAQMCQC-PGENPA--CHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLN 1298
Query: 2071 CDSCTDA 2077
SC A
Sbjct: 1299 GGSCDAA 1305
Score = 97.5 bits (232), Expect = 8e-19
Identities = 97/355 (27%), Positives = 130/355 (36%), Gaps = 49/355 (13%)
Query: 438 ICEDGYYSPECK-NCE-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTC 494
+C D + +C C+ C G+ D C C ++G CN+ C +
Sbjct: 585 VCLDDSFGHDCSLTCDDCRNGGTCLLGLD----GCDCPEGWTGLICNETCPPDTFGKNCS 640
Query: 495 KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPT 553
C+C GT CD V+G C C G G C D C GYY + ++ CNC
Sbjct: 641 FSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKK-----CNCANR 691
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCH 612
G G C C G C P + P C S C +CD +G C
Sbjct: 692 GRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGC-SEECQCVQPHTQSCDKRDGSCS 747
Query: 613 CKSNFDGAKCDTCREQFYNYPAC-EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
CK+ F G +C E Y P C + C C P GV C SV +C QG
Sbjct: 748 CKAGFRGERCQAECELGYFGPGCWQACTC-PVGV-----ACDSVSGECGKRCPAGFQGED 801
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD-QCLD 730
C QE P G NC+ + + C+ +GQC C C+ C +
Sbjct: 802 CG---------QEC-PVGTFGVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCEADCPE 850
Query: 731 GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
G + L ++ C C CD TG C C G RC A ++
Sbjct: 851 GRWGLGCQEI--CPACQHAA------RCDPETGACLCLPGFVGSRCQDVCPAGWY 897
Score = 96.7 bits (230), Expect = 1e-18
Identities = 76/240 (31%), Positives = 108/240 (45%), Gaps = 37/240 (15%)
Query: 1827 ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
+L+CD NG C G G C+ C G+ G+ + + K NCS + + Q
Sbjct: 596 SLTCDDCRNGG----TCLLGLDG--CD-CPEGWTGLICNETCPPDTFGK--NCSFSCSCQ 646
Query: 1887 DPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNC-TACICDEFGMADCDSTT 1944
+ G+CDS+ G C +C +G C + C G+YG K+C C C G C
Sbjct: 647 NGGTCDSVTGAC-RCPPGVSGTNCEDGCPKGYYG-----KHCRKKCNCANRGR--CHRLY 698
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKGVTG 2003
G C+C PG+ G C P W G GC+ C C + + CD +G C C G G
Sbjct: 699 GACLCDPGLYGRFCHLTCPP-WAF--GPGCSEECQC-VQPHTQSCDKRDGSCSCKAGFRG 754
Query: 2004 KQCD-QCAAGFWNYTKDGC-DHCNCNTGYSVGFMCNA-TGQC--ECLPGVIGEKC-DRCP 2057
++C +C G++ GC C C VG C++ +G+C C G GE C CP
Sbjct: 755 ERCQAECELGYFG---PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECP 807
Score = 87.0 bits (206), Expect = 1e-15
Identities = 57/181 (31%), Positives = 72/181 (39%), Gaps = 19/181 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G+C C G C S C G++G + C CP A C G C CP G
Sbjct: 1172 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGS 1231
Query: 1410 NCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVP 1467
C++ C P +F D + C NP C +G C+C G C C P
Sbjct: 1232 GCEQACPPGSFGEDCAQMCQCPGENP--------ACHPATGTCSCAAGYHGPSCQQRCPP 1283
Query: 1468 GHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNPDG 1525
G Y P C Q C C G+ CD T C C T G C+ TC + F + G
Sbjct: 1284 GRYG-PGCEQLCGCLNGGS----CDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG 1338
Query: 1526 C 1526
C
Sbjct: 1339 C 1339
Score = 86.6 bits (205), Expect = 1e-15
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C++ G C C P V G C C GYYG +CR C+C + C G C+C + G
Sbjct: 651 CDSVTGACRCPPGVSGTNCEDGCPKGYYG-KHCRKKCNCANRGRCHRLYGACLCDPGLYG 709
Query: 1409 ENCD-RCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HC 1465
C C P+ F GC ++C C V + C+ G C+C+ RG C C
Sbjct: 710 RFCHLTCPPWAFG----PGCSEECQC----VQPHTQSCDKRDGSCSCKAGFRGERCQAEC 761
Query: 1466 VPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQC--YCKTNVRGQAC-DTCKEEYFNLQDD 1521
G++ P C+Q CTC CD + +C C +G+ C C F +
Sbjct: 762 ELGYFG-PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCS 816
Query: 1522 NPDGCTKCFCFGKTTRC 1538
+ C C G T +C
Sbjct: 817 SSCSCGGAPCHGVTGQC 833
Score = 82.6 bits (195), Expect = 2e-14
Identities = 54/166 (32%), Positives = 74/166 (44%), Gaps = 19/166 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPST-AICDD-NGMCICPKNVE 1407
C+ G C C P G +C AC TG++G P+C PC+C + CD +G+C+C
Sbjct: 913 CHPATGHCSCAPGWTGFSCQRACDTGHWG-PDCSHPCNCSAGHGSCDAISGLCLCEAGYV 971
Query: 1408 GENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCV 1466
G C++ P +F GC+ C C + C+ SG C C RG C+H
Sbjct: 972 GPRCEQQCPQG-HFGP--GCEQLCQCQ------HGAACDHVSGACTCPAGWRGTFCEHAC 1022
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTC 1511
P + DC + CN T CD C C RG C +TC
Sbjct: 1023 PAGFFGLDC-RSACN--CTAGAACDAVNGSCLCPAGRRGPRCAETC 1065
Score = 78.2 bits (184), Expect = 5e-13
Identities = 53/177 (29%), Positives = 69/177 (38%), Gaps = 22/177 (12%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRP-CHCPSTAIC 1394
+ PC C + C+ G C C+ +G C C G++G P C C C A C
Sbjct: 945 SHPCNCS---AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG-PGCEQLCQCQHGAAC 1000
Query: 1395 DD-NGMCICPKNVEGENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
D +G C CP G C+ C F D + C NC G C+A +G C
Sbjct: 1001 DHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC---NCTA-GAA-----CDAVNGSCL 1051
Query: 1453 CRENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C RG C P H +C Q C C + CD QC+C G +C
Sbjct: 1052 CPAGRRGPRCAETCPAHTYGHNCSQACACFNGAS----CDPVHGQCHCAPGWMGPSC 1104
Score = 77.4 bits (182), Expect = 9e-13
Identities = 72/232 (31%), Positives = 90/232 (38%), Gaps = 47/232 (20%)
Query: 1736 CQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C + G CE C G Y + + C C+ +S C+ TG C C G CE
Sbjct: 1395 CSCGLGWTGRHCELACPPGRYG--AACHLECSCHNNST-CEPATGTC-RCGPGFYGQACE 1450
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G+HG G +C C P CD C C G+ G CE
Sbjct: 1451 HPCPPGFHGAGCQG------LCWCQHGAP-------CDPISG----RCLCPAGFHGHFCE 1493
Query: 1854 Y-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
C G +G H + C+C G CD + G CL C +GA CNL
Sbjct: 1494 RGCEPGSFG----EGCH-----QRCDCDGG------APCDPVTGLCL-CPPGRSGATCNL 1537
Query: 1913 -CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
C G +G + CT CD G ADCD +G C C G +G C P
Sbjct: 1538 DCRRGQFGPS-----CTLH-CDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1583
Score = 74.1 bits (174), Expect = 9e-12
Identities = 64/215 (29%), Positives = 86/215 (40%), Gaps = 30/215 (13%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C G C C P G+ C C G++G C C A CD +G C+CP G
Sbjct: 1431 CEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGH 1490
Query: 1410 NCDR-CKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HCV 1466
C+R C+P +F GC C+C+ C+ +G C C G C+ C
Sbjct: 1491 FCERGCEPGSFG----EGCHQRCDCD------GGAPCDPVTGLCLCPPGRSGATCNLDCR 1540
Query: 1467 PGHYAFPDC-YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDG 1525
G + P C C C G D CD + QC+C V G TC+E +NP
Sbjct: 1541 RGQFG-PSCTLHCDC---GGGAD-CDPVSGQCHC---VDGYMGPTCREGGPLRLPENPSL 1592
Query: 1526 CTKCFCFGKTTRCSSSY----YTWAAIDEMVDWYP 1556
G T R ++ +T A+ E V W P
Sbjct: 1593 AQG--LSGHTARLQQTHIPERWTSEALVEAVPWSP 1625
Score = 72.9 bits (171), Expect = 2e-11
Identities = 57/190 (30%), Positives = 77/190 (40%), Gaps = 23/190 (12%)
Query: 1889 GSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGT 1946
G+C + D C G CN C P +G KNC+ +C C G CDS TG
Sbjct: 606 GTC-LLGLDGCDCPEGWTGLICNETCPPDTFG-----KNCSFSCSCQNGGT--CDSVTGA 657
Query: 1947 CVCRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQ 2005
C C PGV G C D C ++G + CNC + +C G C C G+ G+
Sbjct: 658 CRCPPGVSGTNCEDGCPKGYYGKHCR---KKCNC---ANRGRCHRLYGACLCDPGLYGRF 711
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP 2064
C W + + C C ++ C+ G C C G GE+C E P
Sbjct: 712 C-HLTCPPWAFGPGCSEECQCVQPHTQS--CDKRDGSCSCKAGFRGERCQAECELGYFGP 768
Query: 2065 QEGCLECDSC 2074
GC + +C
Sbjct: 769 --GCWQACTC 776
Score = 70.1 bits (164), Expect = 1e-10
Identities = 52/189 (27%), Positives = 73/189 (38%), Gaps = 27/189 (14%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
C+ G C C P G C C +G C C + +C NG C C G
Sbjct: 1345 CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGR 1404
Query: 1410 NCD-RCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CV 1466
+C+ C P + C +C+C+ N CE +G C C G+ C+H C
Sbjct: 1405 HCELACPPGRYG----AACHLECSCH------NNSTCEPATGTCRCGPGFYGQACEHPCP 1454
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT-CKEEYFNLQDDNPDG 1525
PG + C C +HG CD + +C C G C+ C+ F +G
Sbjct: 1455 PGFHGAGCQGLCWC-QHGAP---CDPISGRCLCPAGFHGHFCERGCEPGSFG------EG 1504
Query: 1526 C-TKCFCFG 1533
C +C C G
Sbjct: 1505 CHQRCDCDG 1513
Score = 64.9 bits (151), Expect = 5e-09
Identities = 55/205 (26%), Positives = 80/205 (39%), Gaps = 45/205 (21%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C+ G C C G C AC G++G +CR C+C + A CD NG C+CP G
Sbjct: 1000 CDHVSGACTCPAGWRGTFCEHACPAGFFGL-DCRSACNCTAGAACDAVNGSCLCPAGRRG 1058
Query: 1409 ENC-DRCKPYTFNFDVQRG--------CD----DCNCNP------------LGVVGNQLQ 1443
C + C +T+ + + CD C+C P G+ G+ +
Sbjct: 1059 PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR 1118
Query: 1444 ----------CEADSGKCACRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQ 1492
C+ SG CAC E G C+ C+P + C G +CD
Sbjct: 1119 HSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGG----LCDP 1174
Query: 1493 NTAQCYCKTNVRGQACDT-CKEEYF 1516
+T +C C G C + C +F
Sbjct: 1175 HTGRCLCPAGWTGDKCQSPCLRGWF 1199
Score = 62.9 bits (146), Expect = 2e-08
Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 18/182 (9%)
Query: 1352 CNTFGGQCP--CKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEG 1408
C++ G+C C G C C G +G C C G C CP G
Sbjct: 782 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 841
Query: 1409 ENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
E+C+ C + Q C C + +C+ ++G C C G C P
Sbjct: 842 EDCEADCPEGRWGLGCQEICPACQ--------HAARCDPETGACLCLPGFVGSRCQDVCP 893
Query: 1468 GHYAFPDCY-QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNPDG 1525
+ P C +C+C G C T C C G +C C ++ +P
Sbjct: 894 AGWYGPSCQTRCSCANDGH----CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 949
Query: 1526 CT 1527
C+
Sbjct: 950 CS 951
Score = 59.3 bits (137), Expect = 3e-07
Identities = 43/162 (26%), Positives = 59/162 (36%), Gaps = 17/162 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C+ G C C G +C C G YG P C C C + CD G C CP G
Sbjct: 1259 CHPATGTCSCAAGYHGPSCQQRCPPGRYG-PGCEQLCGCLNGGSCDAATGACRCPTGFLG 1317
Query: 1409 ENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
+C N +G NC + G C+ +G C C G C+ P
Sbjct: 1318 TDC--------NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQ 1369
Query: 1469 HYAFPDC-YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
+ C + C+C G +C + C C G+ C+
Sbjct: 1370 NRFGVGCEHTCSCRNGG----LCHASNGSCSCGLGWTGRHCE 1407
Score = 48.8 bits (111), Expect = 4e-04
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 19/133 (14%)
Query: 1383 CRPCHCPSTAICDDNGMCICPKNVEGENCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGN 1440
C C T + +G C CP+ G C+ C P TF + C C+C G
Sbjct: 599 CDDCRNGGTCLLGLDG-CDCPEGWTGLICNETCPPDTFG----KNCSFSCSCQNGGT--- 650
Query: 1441 QLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
C++ +G C C V G C D C G+Y +C C G C + C C
Sbjct: 651 ---CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR----CHRLYGACLC 703
Query: 1500 KTNVRGQACD-TC 1511
+ G+ C TC
Sbjct: 704 DPGLYGRFCHLTC 716
Score = 45.2 bits (102), Expect = 0.005
Identities = 68/272 (25%), Positives = 87/272 (31%), Gaps = 64/272 (23%)
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSIN 1895
GS C+C PG+ G RC+Y D+ D C+ N G C
Sbjct: 217 GSAQPCHCPPGFQGPRCQY------------DV---DECRTHN----------GGCQH-- 249
Query: 1896 GDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDS-------TTGTCV 1948
+CVN C C PGF S+ C A G C T C
Sbjct: 250 ----RCVNTPGSYLCE-CKPGFRLHT-DSRTCLAINSCALGNGGCQHHCVQLTITRHRCQ 303
Query: 1949 CRPGV-IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
CRPG + E C N C C + +C+ G A G + D
Sbjct: 304 CRPGFQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACEDVD 362
Query: 2008 QCAAGFWN-----YTKDGCDHCNCNTGYSVGF---MC-----NATGQCECLPGVIGEKCD 2054
+CAAG G C C+ GY +G C CE G C
Sbjct: 363 ECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCS 422
Query: 2055 R--------CPERWVL-IPQEGCLECDSCTDA 2077
CP + L Q C++ D C D+
Sbjct: 423 HTSAGPLCTCPRGYELDTDQRTCIDVDDCADS 454
Score = 41.9 bits (94), Expect = 0.042
Identities = 81/329 (24%), Positives = 112/329 (34%), Gaps = 57/329 (17%)
Query: 359 QPCQCDPHF-------STGNCEEESGRCECRPEFQPPD-CSSCAYGYFDYPNCKPC---- 406
QPC C P F C +G C+ R P C G+ + + + C
Sbjct: 220 QPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAIN 279
Query: 407 TCNL-NGTEGEHC---TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYV 462
+C L NG HC T T C C+ + ++ EDG + C N GS +
Sbjct: 280 SCALGNGGCQHHCVQLTITRHRCQCRPGF-----QLQEDGRHCVRRSPC-ANRNGSCMHR 333
Query: 463 CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
C + G C +C GY K C D + G C
Sbjct: 334 CQVVRGLARC----------ECHVGYQLAADGKACE-DVDECAAGLAQCAHG---CLNTQ 379
Query: 523 GGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCN--CLTNFGGAQCDQC 580
G +C C +GY + G RQC + S + +G C+ C G C C
Sbjct: 380 GSFKC-VCHAGYELGADG--RQCYRIEMEIVNSCEAN---NGGCSHGCSHTSAGPLC-TC 432
Query: 581 SPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNC 640
GY D +C DV S C C +N G +C C Y A + C C
Sbjct: 433 PRGYELDTDQRTC-IDVDDCADSPCCQQ---VCTNNPGGYECG-CYAG-YRLSA-DGCGC 485
Query: 641 DPRGVTASFAG-----CGSVPAGELCQCK 664
+ AS G C ++ C C+
Sbjct: 486 EDVDECASSRGGCEHHCTNLAGSFQCSCE 514
>AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 163 bits (395), Expect = 1e-38
Identities = 143/500 (28%), Positives = 199/500 (39%), Gaps = 81/500 (16%)
Query: 292 NCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINC-NKCRPTYYRPYGK 350
+C + + P+ D K S N + +C + NC C P YY P
Sbjct: 130 DCSSECAPGMWGPQCD-KPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGP--- 185
Query: 351 RWDELDVCQ-PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGY--FDYPNCKPC 406
CQ CQC H + C+ ++G C C E P C SC+ G F P+ C
Sbjct: 186 ------ACQFRCQC--HGAP--CDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
Query: 407 TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-CEDGYYSPEC-KNCECNTVGSVSYVCD 464
NG G TP G C C + G C + C +G++ P C + C C+ G +CD
Sbjct: 236 Q---NG--GVFQTP-QGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG----LCD 285
Query: 465 KLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFG 523
+ TG C C Y+G C + C G + + C+C C +G C+C+ GF
Sbjct: 286 RFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDAR----CFPANGACLCEHGFT 341
Query: 524 GPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
G RC C G+Y G Q PC CD S S +G+C+CL + G C++
Sbjct: 342 GDRCTDRLCPDGFY----GLSCQA-PCTCDREHSLSCH-PMNGECSCLPGWAGLHCNESC 395
Query: 582 PGYYKYPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECN 639
P P C C C G +T +GLC C + G C + C Y C+
Sbjct: 396 PQDTHGPGCQEHCLCLHGGVCQAT---SGLCQCAPGYTGPHCASLCPPDTYGVNCSARCS 452
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLA 698
C+ + C + GE C CK+ Q C+ C P W F C +C A
Sbjct: 453 CE------NAIACSPID-GE-CVCKEGWQRGNCSVPCPPGTWG------FSCN-ASCQCA 497
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGC-TECDCDIGGSIDN 756
C+ ++G C C C C G Q + GC + CDCD +
Sbjct: 498 HE----AVCSPQTGACTCTPGWHGAHCQLPCPKG----QFGE--GCASRCDCDHS----D 543
Query: 757 NCDKTTGQCHCHSRVEGRRC 776
CD G+C C + G RC
Sbjct: 544 GCDPVHGRCQCQAGWMGARC 563
Score = 153 bits (371), Expect = 1e-35
Identities = 135/481 (28%), Positives = 190/481 (39%), Gaps = 83/481 (17%)
Query: 315 INGRYEGGGKCLNCQHNTEGINCN-KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
++GR +C C G +C+ +C P + P + D +PC C + +C+
Sbjct: 110 VHGRCVAPNQC-QCVPGWRGDDCSSECAPGMWGP------QCD--KPCSCG---NNSSCD 157
Query: 374 EESGRCECRPEFQPPDC-SSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNY 431
+SG C C QPP+C C GY+ P C+ C C+ G C P G C C
Sbjct: 158 PKSGVCSCPSGLQPPNCLQPCTPGYYG-PACQFRCQCH-----GAPCDPQTGACFCPAER 211
Query: 432 AGKSCEI-CEDG---YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQA 486
G SC++ C G ++ P +C+ V G C+C + G C+ C
Sbjct: 212 TGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ------GSCSCPPGWMGTICSLPCPE 265
Query: 487 GYYNYPTC-KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQ 544
G++ P C + C C G +CD +GQC C G+ G RC ++C G + Q
Sbjct: 266 GFHG-PNCSQECRCHNGG----LCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD 320
Query: 545 CVP-CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLSCNCDVSGSI 601
C P C P A+G C C F G +C C G+Y C CD S+
Sbjct: 321 CAPDARCFP---------ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSL 371
Query: 602 GSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEE-CNCDPRGVTASFAGCGSVPAGEL 660
S NG C C + G C+ Q + P C+E C C GV + +G L
Sbjct: 372 -SCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--------L 422
Query: 661 CQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
CQC G C C P Y +C+C N++ AC+ G+CVCK+
Sbjct: 423 CQCAPGYTGPHCASLCPP-----DTYGVNCSARCSCE-----NAI-ACSPIDGECVCKEG 471
Query: 720 VGERQCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
C C G + N C C + + C TG C C G C
Sbjct: 472 WQRGNCSVPCPPGTWGFSCN-----ASCQC----AHEAVCSPQTGACTCTPGWHGAHCQL 522
Query: 779 P 779
P
Sbjct: 523 P 523
Score = 144 bits (348), Expect = 7e-33
Identities = 114/432 (26%), Positives = 168/432 (38%), Gaps = 65/432 (15%)
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDC-SSCAYGYFDYPNCKPCTCNLNGTEGEH 417
Q C+C + G C+ +G+C C P + C C G F + C C
Sbjct: 274 QECRCH---NGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC----APDAR 326
Query: 418 CTPTDGLCPCKYNYAGKSC--EICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKS 474
C P +G C C++ + G C +C DG+Y C+ C C+ S+S C + G+C+C
Sbjct: 327 CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS--CHPMNGECSCLP 384
Query: 475 KYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSG 533
++G CN+ + P C+ C C G +C SG C C G+ GP C
Sbjct: 385 GWAGLHCNESCPQDTHGPGCQEHCLCLHGG----VCQATSGLCQCAPGYTGPHCASLCPP 440
Query: 534 YYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCD-QCSPGYYKYPDCL 591
V R C+C+ + +CS DG+C C + C C PG + +
Sbjct: 441 DTYGVNCSAR----CSCE----NAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGF---- 488
Query: 592 SCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASF 649
SCN + + C G C C + GA C C + + C+CD
Sbjct: 489 SCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSD----- 543
Query: 650 AGCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN 708
GC P CQC+ G C+ C W + NC+ T + G C
Sbjct: 544 -GCD--PVHGRCQCQAGWMGARCHLSCPEGLWGV-----------NCSNTCTCKNGGTCL 589
Query: 709 TKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
++G CVC C + C G Y + C C C + + C + G C+C
Sbjct: 590 PENGNCVCAPGFRGPSCQRSCQPGRYGKR------CVPCKC----ANHSFCHPSNGTCYC 639
Query: 768 HSRVEGRRCDQP 779
+ G C QP
Sbjct: 640 LAGWTGPDCSQP 651
Score = 124 bits (300), Expect = 5e-27
Identities = 113/403 (28%), Positives = 152/403 (37%), Gaps = 64/403 (15%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQP-CQCDPHFSTGNCEEESGRCEC 381
G+C +C G++CN+ P G CQ C C G C+ SG C+C
Sbjct: 378 GEC-SCLPGWAGLHCNESCPQDTHGPG--------CQEHCLC---LHGGVCQATSGLCQC 425
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-C 439
P + P C+S NC C+C C+P DG C CK + +C + C
Sbjct: 426 APGYTGPHCASLCPPDTYGVNCSARCSCE----NAIACSPIDGECVCKEGWQRGNCSVPC 481
Query: 440 EDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPC 497
G + C +C+C + VC TG CTC + G C C G + C
Sbjct: 482 PPGTWGFSCNASCQC----AHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC 537
Query: 498 NCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQCVPCNCDPTGST 556
+CD S CD V G+C C+AG+ G RC C G + C C G
Sbjct: 538 DCDHSDG----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSN-----TCTCKNGG-- 586
Query: 557 STSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTC-DDNGLCHCK 614
T +G C C F G C + C PG Y C+ C C + S C NG C+C
Sbjct: 587 -TCLPENGNCVCAPGFRGPSCQRSCQPGRYG-KRCVPCKC----ANHSFCHPSNGTCYCL 640
Query: 615 SNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN 673
+ + G C C + + C C G C P C C G C
Sbjct: 641 AGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT------CH--PQDGSCICPLGWTGHHCL 692
Query: 674 DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVC 716
+ PL FG NC+ C+ ++G CVC
Sbjct: 693 EGCPL-------GTFG---ANCSQPCQCGPGEKCHPETGACVC 725
Score = 121 bits (291), Expect = 6e-26
Identities = 111/368 (30%), Positives = 148/368 (40%), Gaps = 70/368 (19%)
Query: 1724 ELVVRRATSVEECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICL 1782
E V R + +CQC +RG C +CA G + PC C G++ CD +G+C
Sbjct: 108 ECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCD--KPCSC-GNNSSCDPKSGVC- 163
Query: 1783 NCADNTIGDHC-EFCMSGYHGDATV------GTPRD--CLICACPMPYPSNNFALSCDLS 1833
+C +C + C GY+G A G P D C CP + +SC
Sbjct: 164 SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQG 223
Query: 1834 ------------ENGSLI-----SCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCK 1875
+NG + SC+C PG+ G C C G++G P
Sbjct: 224 TSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-P------------ 270
Query: 1876 PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNCTACICDE 1934
NCS + G CD G C +C G C C G +G ++C A CD
Sbjct: 271 --NCSQECRCHNGGLCDRFTGQC-RCAPGYTGDRCREECPVGRFG-----QDC-AETCDC 321
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLNTGLGC-TPCNCGIASESTQCDDDN 1992
A C G C+C G G++C DR PD + GL C PC C S C N
Sbjct: 322 APDARCFPANGACLCEHGFTGDRCTDRLCPDGF---YGLSCQAPCTCD-REHSLSCHPMN 377
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKDGC-DHCNCNTGYSVGFMCNAT-GQCECLPGVIG 2050
G+C C G G C++ + GC +HC C G +C AT G C+C PG G
Sbjct: 378 GECSCLPGWAGLHCNESCP--QDTHGPGCQEHCLC----LHGGVCQATSGLCQCAPGYTG 431
Query: 2051 EKC-DRCP 2057
C CP
Sbjct: 432 PHCASLCP 439
Score = 109 bits (263), Expect = 1e-22
Identities = 95/326 (29%), Positives = 120/326 (36%), Gaps = 63/326 (19%)
Query: 1735 ECQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC C ++ +C C G + CQC H C TG C C G HC
Sbjct: 465 ECVCKEGWQRGNCSVPCPPGTWGFSCN--ASCQC-AHEAVCSPQTGAC-TCTPGWHGAHC 520
Query: 1794 EF-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G G+ C C + + CD C CQ G+ GARC
Sbjct: 521 QLPCPKGQFGEGCASR------CDC-------DHSDGCDPVHG----RCQCQAGWMGARC 563
Query: 1853 EY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC- 1910
C G +G+ NCS ++ G+C NG+C+ C G +C
Sbjct: 564 HLSCPEGLWGV---------------NCSNTCTCKNGGTCLPENGNCV-CAPGFRGPSCQ 607
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLN 1969
C PG YG K C C C C + GTC C G G C + C P HWG N
Sbjct: 608 RSCQPGRYG-----KRCVPCKCANHSF--CHPSNGTCYCLAGWTGPDCSQPCPPGHWGEN 660
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCNT 2028
C C+ G C +G C C G TG C + C G + + C C
Sbjct: 661 CAQTC-QCHHG-----GTCHPQDGSCICPLGWTGHHCLEGCPLG--TFGANCSQPCQCGP 712
Query: 2029 GYSVGFMCN-ATGQCECLPGVIGEKC 2053
G C+ TG C C PG G C
Sbjct: 713 GEK----CHPETGACVCPPGHSGAPC 734
Score = 107 bits (257), Expect = 7e-22
Identities = 97/343 (28%), Positives = 131/343 (38%), Gaps = 46/343 (13%)
Query: 1735 ECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
+C+C Y G C E+C G R C C + +C G CL C GD C
Sbjct: 290 QCRCAPGYTGDRCREECPVG--RFGQDCAETCDCAPDA-RCFPANGACL-CEHGFTGDRC 345
Query: 1794 --EFCMSGYHG---DATVGTPRDCLI--------CACPMPYPSNNFALSCDLSENGSLIS 1840
C G++G A R+ + C+C + + SC +G
Sbjct: 346 TDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQ 405
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP----CNCSGNINPQDPGSCDSING 1896
+C +GG C+ + P T H C P NCS + ++ +C I+G
Sbjct: 406 EHCLCLHGGV-CQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG 464
Query: 1897 DCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG 1955
+C+ C C++ C PG +G FS N + C C A C TG C C PG G
Sbjct: 465 ECV-CKEGWQRGNCSVPCPPGTWG---FSCNAS-CQCAH--EAVCSPQTGACTCTPGWHG 517
Query: 1956 EKCDRCAPDHWGLNTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C P G GC C+C S CD +G+C+C G G +C C G
Sbjct: 518 AHCQLPCPKG---QFGEGCASRCDC---DHSDGCDPVHGRCQCQAGWMGARCHLSCPEGL 571
Query: 2014 WNYTKDGCDH-CNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
W C + C C G G G C C PG G C R
Sbjct: 572 WGVN---CSNTCTCKNG---GTCLPENGNCVCAPGFRGPSCQR 608
Score = 103 bits (247), Expect = 1e-20
Identities = 109/382 (28%), Positives = 136/382 (35%), Gaps = 79/382 (20%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C CP + +C Q C G+Y F CQC H CD TG C A+ T G C+
Sbjct: 163 CSCPSGLQPPNCLQPCTPGYYGPACQF--RCQC--HGAPCDPQTGACFCPAERT-GPSCD 217
Query: 1795 ----------FCMSGY--HGDATVGTPRDCLICA-------CPMPYPSNNFALSCDLS-- 1833
FC S + TP+ C C +P P +C
Sbjct: 218 VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECR 277
Query: 1834 -ENGSLIS-----CNCQPGYGGARC-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
NG L C C PGY G RC E C G +G D + C+C+ +
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFG---------QDCAETCDCAPDAR-- 326
Query: 1887 DPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDAIFSKNCTA-CICDEFGMADCDST 1943
C NG CL C + G C LC GFYG +C A C CD C
Sbjct: 327 ----CFPANGACL-CEHGFTGDRCTDRLCPDGFYG-----LSCQAPCTCDREHSLSCHPM 376
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTG 2003
G C C PG G C+ P G GC +C + C +G C+CA G TG
Sbjct: 377 NGECSCLPGWAGLHCNESCPQD---THGPGCQE-HC-LCLHGGVCQATSGLCQCAPGYTG 431
Query: 2004 KQC-DQCAAGFWNYTKDGCDHCNCNTGYSVG-----FMCN---ATGQCE--CLPGVIGEK 2052
C C Y + C+C + +C G C C PG G
Sbjct: 432 PHCASLCPPD--TYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFS 489
Query: 2053 CD---RCPERWVLIPQEGCLEC 2071
C+ +C V PQ G C
Sbjct: 490 CNASCQCAHEAVCSPQTGACTC 511
Score = 97.5 bits (232), Expect = 8e-19
Identities = 102/343 (29%), Positives = 130/343 (37%), Gaps = 44/343 (12%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQCNG-HSDQCDVNTGICLNCADNTIGDH 1792
C C + G C C +G Y L PC C+ HS C G C +C G H
Sbjct: 334 CLCEHGFTGDRCTDRLCPDGFYGLSCQ--APCTCDREHSLSCHPMNGEC-SCLPGWAGLH 390
Query: 1793 C-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG-YG-- 1848
C E C HG G CL C + + C G + C P YG
Sbjct: 391 CNESCPQDTHGP---GCQEHCL-CLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVN 446
Query: 1849 -GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPG-SCDSINGDCLKCVNNTA 1906
ARC C P D + + + NCS P G SC++ + V +
Sbjct: 447 CSARCS-CENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQ 505
Query: 1907 GAACNLCAPGFYG--------DAIFSKNCTA-CICDEFGMADCDSTTGTCVCRPGVIGEK 1957
AC C PG++G F + C + C CD CD G C C+ G +G +
Sbjct: 506 TGACT-CTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSD--GCDPVHGRCQCQAGWMGAR 562
Query: 1958 CDRCAPDH-WGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWN 2015
C P+ WG+N CT N G C +NG C CA G G C + C G
Sbjct: 563 CHLSCPEGLWGVNCSNTCTCKNGGT------CLPENGNCVCAPGFRGPSCQRSCQPG--R 614
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
Y K C C C +S F + G C CL G G C + CP
Sbjct: 615 YGKR-CVPCKC-ANHS--FCHPSNGTCYCLAGWTGPDCSQPCP 653
Score = 93.5 bits (222), Expect = 1e-17
Identities = 78/312 (25%), Positives = 110/312 (35%), Gaps = 50/312 (16%)
Query: 227 IGGRCMCNG--HADTCEPADPAGNLNILV---CRCQHNT-CGPQCNKCCSGFEQKKWRIS 280
I G C+C C P G C+C H C PQ C +
Sbjct: 462 IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTC---------T 512
Query: 281 QNWDRFSCE-PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
W C+ PC C + D ++GR + CQ G C+
Sbjct: 513 PGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQ-------CQAGWMGARCHL 565
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYF 398
P W ++ C C + G C E+G C C P F+ P C SC G +
Sbjct: 566 SCPEGL------WG-VNCSNTCTCK---NGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY 615
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC-EICEDGYYSPEC-KNCECNTV 456
C PC C C P++G C C + G C + C G++ C + C+C+
Sbjct: 616 G-KRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG 670
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ 515
G+ C G C C ++G C + C G + +PC C C +G
Sbjct: 671 GT----CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEK----CHPETGA 722
Query: 516 CICKAGFGGPRC 527
C+C G G C
Sbjct: 723 CVCPPGHSGAPC 734
Score = 83.4 bits (197), Expect = 1e-14
Identities = 99/334 (29%), Positives = 134/334 (40%), Gaps = 66/334 (19%)
Query: 1749 QCAEGHYRLPSGFCVP-CQCNGHSDQCDVNTGICLNCADNTIGDHCEF-CMSGYHGDATV 1806
QC G Y GFCVP C +C V C C GD C C G G
Sbjct: 89 QCCHGFYE-SRGFCVPLCAQECVHGRC-VAPNQC-QCVPGWRGDDCSSECAPGMWG---- 141
Query: 1807 GTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC-EYCAAGYYGIPED 1865
P+ C+C NN SCD ++G C+C G C + C GYYG
Sbjct: 142 --PQCDKPCSC-----GNNS--SCD-PKSGV---CSCPSGLQPPNCLQPCTPGYYG---- 184
Query: 1866 TDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIF 1923
C+ C C G CD G C C G +C++ C+ G G F
Sbjct: 185 ------PACQFRCQCHG-------APCDPQTGACF-CPAERTGPSCDVSCSQGTSG--FF 228
Query: 1924 SKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHW-GLNTGLGCTPCNCGIA 1982
+ +C G+ + G+C C PG +G C P+ + G N C N G+
Sbjct: 229 CPSTHSC--QNGGVFQ--TPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGL- 283
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMC-NATG 2040
CD GQCRCA G TG +C ++C G + +D + C+C + C A G
Sbjct: 284 -----CDRFTGQCRCAPGYTGDRCREECPVG--RFGQDCAETCDC----APDARCFPANG 332
Query: 2041 QCECLPGVIGEKC-DR-CPERWVLIPQEGCLECD 2072
C C G G++C DR CP+ + + + CD
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCD 366
Score = 77.0 bits (181), Expect = 1e-12
Identities = 57/200 (28%), Positives = 78/200 (39%), Gaps = 29/200 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICD- 1395
PC CD S L C+ G+C C P G C+ +C +G P C+ C C +C
Sbjct: 362 PCTCDREHS--LSCHPMNGECSCLPGWAGLHCNESCPQDTHG-PGCQEHCLCLHGGVCQA 418
Query: 1396 DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
+G+C C G +C C P T+ + C+C N + C G+C C+
Sbjct: 419 TSGLCQCAPGYTGPHCASLCPPDTYGVNCSA---RCSCE------NAIACSPIDGECVCK 469
Query: 1455 EN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCK 1512
E RG C PG + F C C VC T C C G C C
Sbjct: 470 EGWQRGNCSVPCPPGTWGFSCNASCQCAHEA----VCSPQTGACTCTPGWHGAHCQLPCP 525
Query: 1513 EEYFNLQDDNPDGC-TKCFC 1531
+ F +GC ++C C
Sbjct: 526 KGQFG------EGCASRCDC 539
Score = 75.8 bits (178), Expect = 3e-12
Identities = 52/195 (26%), Positives = 69/195 (35%), Gaps = 23/195 (11%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAIC- 1394
A C CD C+ G+C C+ +G C +C G +G C C + C
Sbjct: 534 ASRCDCDHSDG----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCL 589
Query: 1395 DDNGMCICPKNVEGENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCAC 1453
+NG C+C G +C R C+P + + C C C N C +G C C
Sbjct: 590 PENGNCVCAPGFRGPSCQRSCQPGRYG----KRCVPCKC------ANHSFCHPSNGTCYC 639
Query: 1454 RENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTC 1511
G C C PGH+ C C+ GT C C C G C + C
Sbjct: 640 LAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCLEGC 695
Query: 1512 KEEYFNLQDDNPDGC 1526
F P C
Sbjct: 696 PLGTFGANCSQPCQC 710
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/181 (29%), Positives = 69/181 (38%), Gaps = 25/181 (13%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCR-PCHCPSTAICD 1395
+PC C S C+ G C C + C C GYYG P C+ C C
Sbjct: 146 KPCSCGNNSS----CDPKSGVCSCPSGLQPPNCLQPCTPGYYG-PACQFRCQCHGAPCDP 200
Query: 1396 DNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
G C CP G +CD C T F +C GV + G C+C
Sbjct: 201 QTGACFCPAERTGPSCDVSCSQGTSGFFCP---STHSCQNGGVF------QTPQGSCSCP 251
Query: 1455 ENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE 1513
G +C P + P+C Q C C+ G +CD+ T QC C G D C+E
Sbjct: 252 PGWMGTICSLPCPEGFHGPNCSQECRCHNGG----LCDRFTGQCRCAPGYTG---DRCRE 304
Query: 1514 E 1514
E
Sbjct: 305 E 305
Score = 71.7 bits (168), Expect = 5e-11
Identities = 49/162 (30%), Positives = 61/162 (37%), Gaps = 16/162 (9%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCRPCHCPSTAIC-DDNGMCICPKNVEGE 1409
C+ F GQC C P G C C G +G C C A C NG C+C G+
Sbjct: 284 CDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGD 343
Query: 1410 NC-DRCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C DR P F C C C+ + L C +G+C+C G C+ P
Sbjct: 344 RCTDRLCPDGF---YGLSCQAPCTCDR----EHSLSCHPMNGECSCLPGWAGLHCNESCP 396
Query: 1468 GHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
P C + C C HG VC + C C G C
Sbjct: 397 QDTHGPGCQEHCLC-LHG---GVCQATSGLCQCAPGYTGPHC 434
Score = 66.5 bits (155), Expect = 2e-09
Identities = 46/163 (28%), Positives = 54/163 (33%), Gaps = 16/163 (9%)
Query: 1349 ELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNV 1406
E C+ G C C P G C C G +G C C + CD +G C C
Sbjct: 499 EAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGW 558
Query: 1407 EGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-C 1465
G C P G NC+ N C ++G C C RG C C
Sbjct: 559 MGARCHLSCP--------EGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSC 610
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
PG Y C C C H C + CYC G C
Sbjct: 611 QPGRYG-KRCVPCKCANH----SFCHPSNGTCYCLAGWTGPDC 648
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/196 (27%), Positives = 73/196 (37%), Gaps = 28/196 (14%)
Query: 1358 QCPCKPNVIGRTCSA-CRTGYYGFPNC-RPCHCPSTAICD-DNGMCICPKNVEGENC-DR 1413
QC C P G CS+ C G +G P C +PC C + + CD +G+C CP ++ NC
Sbjct: 119 QCQCVPGWRGDDCSSECAPGMWG-PQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQP 177
Query: 1414 CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HCVPGHYAF 1472
C P + Q C C+ P C+ +G C C G CD C G F
Sbjct: 178 CTPGYYGPACQFRC-QCHGAP---------CDPQTGACFCPAERTGPSCDVSCSQGTSGF 227
Query: 1473 --PDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNPDGCTK- 1528
P + C ++G + C C G C C E + C
Sbjct: 228 FCPSTHSC---QNGGVFQT---PQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNG 281
Query: 1529 --CFCFGKTTRCSSSY 1542
C F RC+ Y
Sbjct: 282 GLCDRFTGQCRCAPGY 297
Score = 56.8 bits (131), Expect = 1e-06
Identities = 57/223 (25%), Positives = 79/223 (35%), Gaps = 36/223 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
RC C+ H+D C+P C+CQ G +C+ C + W ++ + + +C+
Sbjct: 536 RCDCD-HSDGCDPVHGR-------CQCQAGWMGARCHLSCP---EGLWGVNCS-NTCTCK 583
Query: 290 PCN-CHNHTTECTYDPEIDEKRLSLDIN-GRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C C P GRY G +C+ C+ C+ T Y
Sbjct: 584 NGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY--GKRCVPCKCANHSF-CHPSNGTCYCL 640
Query: 348 YGKRWDELDVCQPCQ-----------CDPHFSTGNCEEESGRCECRPEFQPPDC-SSCAY 395
G W D QPC C H G C + G C C + C C
Sbjct: 641 AG--WTGPDCSQPCPPGHWGENCAQTCQCHHG-GTCHPQDGSCICPLGWTGHHCLEGCPL 697
Query: 396 GYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI 438
G F +PC C GE C P G C C ++G C I
Sbjct: 698 GTFGANCSQPCQCG----PGEKCHPETGACVCPPGHSGAPCRI 736
Score = 53.2 bits (122), Expect = 2e-05
Identities = 37/133 (27%), Positives = 50/133 (37%), Gaps = 16/133 (12%)
Query: 1333 YNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPST 1391
Y PC C + C+ G C C G CS C G++G + C C
Sbjct: 615 YGKRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG 670
Query: 1392 AICD-DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
C +G CICP G +C + C TF + + C C P G + C ++G
Sbjct: 671 GTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQ---PCQCGP----GEK--CHPETG 721
Query: 1450 KCACRENVRGRVC 1462
C C G C
Sbjct: 722 ACVCPPGHSGAPC 734
Score = 52.0 bits (119), Expect = 4e-05
Identities = 51/207 (24%), Positives = 72/207 (34%), Gaps = 31/207 (14%)
Query: 1338 RPCLCDFMG-STELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP----CHCPSTA 1392
+PC + G + + C G PC P C A RTG +C CPST
Sbjct: 176 QPCTPGYYGPACQFRCQCHGA--PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTH 233
Query: 1393 ICDDNGM-------CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C + G+ C CP G C P F +C C+ G+ C+
Sbjct: 234 SCQNGGVFQTPQGSCSCPPGWMGTICSL--PCPEGFHGPNCSQECRCHNGGL------CD 285
Query: 1446 ADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+G+C C G C + C G + DC + C C C C C+
Sbjct: 286 RFTGQCRCAPGYTGDRCREECPVGRFG-QDCAETCDCAPDAR----CFPANGACLCEHGF 340
Query: 1504 RGQACD--TCKEEYFNLQDDNPDGCTK 1528
G C C + ++ L P C +
Sbjct: 341 TGDRCTDRLCPDGFYGLSCQAPCTCDR 367
Score = 36.7 bits (81), Expect = 1.6
Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 6/99 (6%)
Query: 699 GTLNSLGACNTKSGQ-CVCKQHVGERQCDQCLDGFYR--LQTNDVFGCTECDCDIGGSID 755
G S G C Q CV + V QC QC+ G+ + G CD S
Sbjct: 93 GFYESRGFCVPLCAQECVHGRCVAPNQC-QCVPGWRGDDCSSECAPGMWGPQCDKPCSCG 151
Query: 756 NN--CDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQFQ 792
NN CD +G C C S ++ C QP Y+ QF+
Sbjct: 152 NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR 190
>AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 163 bits (395), Expect = 1e-38
Identities = 143/500 (28%), Positives = 199/500 (39%), Gaps = 81/500 (16%)
Query: 292 NCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINC-NKCRPTYYRPYGK 350
+C + + P+ D K S N + +C + NC C P YY P
Sbjct: 130 DCSSECAPGMWGPQCD-KPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGP--- 185
Query: 351 RWDELDVCQ-PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGY--FDYPNCKPC 406
CQ CQC H + C+ ++G C C E P C SC+ G F P+ C
Sbjct: 186 ------ACQFRCQC--HGAP--CDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
Query: 407 TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-CEDGYYSPEC-KNCECNTVGSVSYVCD 464
NG G TP G C C + G C + C +G++ P C + C C+ G +CD
Sbjct: 236 Q---NG--GVFQTP-QGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG----LCD 285
Query: 465 KLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFG 523
+ TG C C Y+G C + C G + + C+C C +G C+C+ GF
Sbjct: 286 RFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDAR----CFPANGACLCEHGFT 341
Query: 524 GPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
G RC C G+Y G Q PC CD S S +G+C+CL + G C++
Sbjct: 342 GDRCTDRLCPDGFY----GLSCQA-PCTCDREHSLSCH-PMNGECSCLPGWAGLHCNESC 395
Query: 582 PGYYKYPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECN 639
P P C C C G +T +GLC C + G C + C Y C+
Sbjct: 396 PQDTHGPGCQEHCLCLHGGVCQAT---SGLCQCAPGYTGPHCASLCPPDTYGVNCSARCS 452
Query: 640 CDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLA 698
C+ + C + GE C CK+ Q C+ C P W F C +C A
Sbjct: 453 CE------NAIACSPID-GE-CVCKEGWQRGNCSVPCPPGTWG------FSCN-ASCQCA 497
Query: 699 GTLNSLGACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGC-TECDCDIGGSIDN 756
C+ ++G C C C C G Q + GC + CDCD +
Sbjct: 498 HE----AVCSPQTGACTCTPGWHGAHCQLPCPKG----QFGE--GCASRCDCDHS----D 543
Query: 757 NCDKTTGQCHCHSRVEGRRC 776
CD G+C C + G RC
Sbjct: 544 GCDPVHGRCQCQAGWMGARC 563
Score = 153 bits (371), Expect = 1e-35
Identities = 135/481 (28%), Positives = 190/481 (39%), Gaps = 83/481 (17%)
Query: 315 INGRYEGGGKCLNCQHNTEGINCN-KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
++GR +C C G +C+ +C P + P + D +PC C + +C+
Sbjct: 110 VHGRCVAPNQC-QCVPGWRGDDCSSECAPGMWGP------QCD--KPCSCG---NNSSCD 157
Query: 374 EESGRCECRPEFQPPDC-SSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNY 431
+SG C C QPP+C C GY+ P C+ C C+ G C P G C C
Sbjct: 158 PKSGVCSCPSGLQPPNCLQPCTPGYYG-PACQFRCQCH-----GAPCDPQTGACFCPAER 211
Query: 432 AGKSCEI-CEDG---YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQA 486
G SC++ C G ++ P +C+ V G C+C + G C+ C
Sbjct: 212 TGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ------GSCSCPPGWMGTICSLPCPE 265
Query: 487 GYYNYPTC-KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQ 544
G++ P C + C C G +CD +GQC C G+ G RC ++C G + Q
Sbjct: 266 GFHG-PNCSQECRCHNGG----LCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD 320
Query: 545 CVP-CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLSCNCDVSGSI 601
C P C P A+G C C F G +C C G+Y C CD S+
Sbjct: 321 CAPDARCFP---------ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSL 371
Query: 602 GSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEE-CNCDPRGVTASFAGCGSVPAGEL 660
S NG C C + G C+ Q + P C+E C C GV + +G L
Sbjct: 372 -SCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--------L 422
Query: 661 CQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
CQC G C C P Y +C+C N++ AC+ G+CVCK+
Sbjct: 423 CQCAPGYTGPHCASLCPP-----DTYGVNCSARCSCE-----NAI-ACSPIDGECVCKEG 471
Query: 720 VGERQCD-QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
C C G + N C C + + C TG C C G C
Sbjct: 472 WQRGNCSVPCPPGTWGFSCN-----ASCQC----AHEAVCSPQTGACTCTPGWHGAHCQL 522
Query: 779 P 779
P
Sbjct: 523 P 523
Score = 144 bits (348), Expect = 7e-33
Identities = 114/432 (26%), Positives = 168/432 (38%), Gaps = 65/432 (15%)
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDC-SSCAYGYFDYPNCKPCTCNLNGTEGEH 417
Q C+C + G C+ +G+C C P + C C G F + C C
Sbjct: 274 QECRCH---NGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC----APDAR 326
Query: 418 CTPTDGLCPCKYNYAGKSC--EICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKS 474
C P +G C C++ + G C +C DG+Y C+ C C+ S+S C + G+C+C
Sbjct: 327 CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS--CHPMNGECSCLP 384
Query: 475 KYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSG 533
++G CN+ + P C+ C C G +C SG C C G+ GP C
Sbjct: 385 GWAGLHCNESCPQDTHGPGCQEHCLCLHGG----VCQATSGLCQCAPGYTGPHCASLCPP 440
Query: 534 YYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCD-QCSPGYYKYPDCL 591
V R C+C+ + +CS DG+C C + C C PG + +
Sbjct: 441 DTYGVNCSAR----CSCE----NAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGF---- 488
Query: 592 SCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASF 649
SCN + + C G C C + GA C C + + C+CD
Sbjct: 489 SCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSD----- 543
Query: 650 AGCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN 708
GC P CQC+ G C+ C W + NC+ T + G C
Sbjct: 544 -GCD--PVHGRCQCQAGWMGARCHLSCPEGLWGV-----------NCSNTCTCKNGGTCL 589
Query: 709 TKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
++G CVC C + C G Y + C C C + + C + G C+C
Sbjct: 590 PENGNCVCAPGFRGPSCQRSCQPGRYGKR------CVPCKC----ANHSFCHPSNGTCYC 639
Query: 768 HSRVEGRRCDQP 779
+ G C QP
Sbjct: 640 LAGWTGPDCSQP 651
Score = 124 bits (300), Expect = 5e-27
Identities = 113/403 (28%), Positives = 152/403 (37%), Gaps = 64/403 (15%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQP-CQCDPHFSTGNCEEESGRCEC 381
G+C +C G++CN+ P G CQ C C G C+ SG C+C
Sbjct: 378 GEC-SCLPGWAGLHCNESCPQDTHGPG--------CQEHCLC---LHGGVCQATSGLCQC 425
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-C 439
P + P C+S NC C+C C+P DG C CK + +C + C
Sbjct: 426 APGYTGPHCASLCPPDTYGVNCSARCSCE----NAIACSPIDGECVCKEGWQRGNCSVPC 481
Query: 440 EDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPC 497
G + C +C+C + VC TG CTC + G C C G + C
Sbjct: 482 PPGTWGFSCNASCQC----AHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC 537
Query: 498 NCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQCVPCNCDPTGST 556
+CD S CD V G+C C+AG+ G RC C G + C C G
Sbjct: 538 DCDHSDG----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSN-----TCTCKNGG-- 586
Query: 557 STSCSADGKCNCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTC-DDNGLCHCK 614
T +G C C F G C + C PG Y C+ C C + S C NG C+C
Sbjct: 587 -TCLPENGNCVCAPGFRGPSCQRSCQPGRYG-KRCVPCKC----ANHSFCHPSNGTCYCL 640
Query: 615 SNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN 673
+ + G C C + + C C G C P C C G C
Sbjct: 641 AGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT------CH--PQDGSCICPLGWTGHHCL 692
Query: 674 DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVC 716
+ PL FG NC+ C+ ++G CVC
Sbjct: 693 EGCPL-------GTFG---ANCSQPCQCGPGEKCHPETGACVC 725
Score = 121 bits (291), Expect = 6e-26
Identities = 111/368 (30%), Positives = 148/368 (40%), Gaps = 70/368 (19%)
Query: 1724 ELVVRRATSVEECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICL 1782
E V R + +CQC +RG C +CA G + PC C G++ CD +G+C
Sbjct: 108 ECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCD--KPCSC-GNNSSCDPKSGVC- 163
Query: 1783 NCADNTIGDHC-EFCMSGYHGDATV------GTPRD--CLICACPMPYPSNNFALSCDLS 1833
+C +C + C GY+G A G P D C CP + +SC
Sbjct: 164 SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQG 223
Query: 1834 ------------ENGSLI-----SCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCK 1875
+NG + SC+C PG+ G C C G++G P
Sbjct: 224 TSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-P------------ 270
Query: 1876 PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNCTACICDE 1934
NCS + G CD G C +C G C C G +G ++C A CD
Sbjct: 271 --NCSQECRCHNGGLCDRFTGQC-RCAPGYTGDRCREECPVGRFG-----QDC-AETCDC 321
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLNTGLGC-TPCNCGIASESTQCDDDN 1992
A C G C+C G G++C DR PD + GL C PC C S C N
Sbjct: 322 APDARCFPANGACLCEHGFTGDRCTDRLCPDGF---YGLSCQAPCTCD-REHSLSCHPMN 377
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKDGC-DHCNCNTGYSVGFMCNAT-GQCECLPGVIG 2050
G+C C G G C++ + GC +HC C G +C AT G C+C PG G
Sbjct: 378 GECSCLPGWAGLHCNESCP--QDTHGPGCQEHCLC----LHGGVCQATSGLCQCAPGYTG 431
Query: 2051 EKC-DRCP 2057
C CP
Sbjct: 432 PHCASLCP 439
Score = 109 bits (263), Expect = 1e-22
Identities = 95/326 (29%), Positives = 120/326 (36%), Gaps = 63/326 (19%)
Query: 1735 ECQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC C ++ +C C G + CQC H C TG C C G HC
Sbjct: 465 ECVCKEGWQRGNCSVPCPPGTWGFSCN--ASCQC-AHEAVCSPQTGAC-TCTPGWHGAHC 520
Query: 1794 EF-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
+ C G G+ C C + + CD C CQ G+ GARC
Sbjct: 521 QLPCPKGQFGEGCASR------CDC-------DHSDGCDPVHG----RCQCQAGWMGARC 563
Query: 1853 EY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC- 1910
C G +G+ NCS ++ G+C NG+C+ C G +C
Sbjct: 564 HLSCPEGLWGV---------------NCSNTCTCKNGGTCLPENGNCV-CAPGFRGPSCQ 607
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLN 1969
C PG YG K C C C C + GTC C G G C + C P HWG N
Sbjct: 608 RSCQPGRYG-----KRCVPCKCANHSF--CHPSNGTCYCLAGWTGPDCSQPCPPGHWGEN 660
Query: 1970 TGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCNT 2028
C C+ G C +G C C G TG C + C G + + C C
Sbjct: 661 CAQTC-QCHHG-----GTCHPQDGSCICPLGWTGHHCLEGCPLG--TFGANCSQPCQCGP 712
Query: 2029 GYSVGFMCN-ATGQCECLPGVIGEKC 2053
G C+ TG C C PG G C
Sbjct: 713 GEK----CHPETGACVCPPGHSGAPC 734
Score = 107 bits (257), Expect = 7e-22
Identities = 97/343 (28%), Positives = 131/343 (38%), Gaps = 46/343 (13%)
Query: 1735 ECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
+C+C Y G C E+C G R C C + +C G CL C GD C
Sbjct: 290 QCRCAPGYTGDRCREECPVG--RFGQDCAETCDCAPDA-RCFPANGACL-CEHGFTGDRC 345
Query: 1794 --EFCMSGYHG---DATVGTPRDCLI--------CACPMPYPSNNFALSCDLSENGSLIS 1840
C G++G A R+ + C+C + + SC +G
Sbjct: 346 TDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQ 405
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP----CNCSGNINPQDPGSCDSING 1896
+C +GG C+ + P T H C P NCS + ++ +C I+G
Sbjct: 406 EHCLCLHGGV-CQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG 464
Query: 1897 DCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG 1955
+C+ C C++ C PG +G FS N + C C A C TG C C PG G
Sbjct: 465 ECV-CKEGWQRGNCSVPCPPGTWG---FSCNAS-CQCAH--EAVCSPQTGACTCTPGWHG 517
Query: 1956 EKCDRCAPDHWGLNTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C P G GC C+C S CD +G+C+C G G +C C G
Sbjct: 518 AHCQLPCPKG---QFGEGCASRCDC---DHSDGCDPVHGRCQCQAGWMGARCHLSCPEGL 571
Query: 2014 WNYTKDGCDH-CNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
W C + C C G G G C C PG G C R
Sbjct: 572 WGVN---CSNTCTCKNG---GTCLPENGNCVCAPGFRGPSCQR 608
Score = 103 bits (247), Expect = 1e-20
Identities = 109/382 (28%), Positives = 136/382 (35%), Gaps = 79/382 (20%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C CP + +C Q C G+Y F CQC H CD TG C A+ T G C+
Sbjct: 163 CSCPSGLQPPNCLQPCTPGYYGPACQF--RCQC--HGAPCDPQTGACFCPAERT-GPSCD 217
Query: 1795 ----------FCMSGY--HGDATVGTPRDCLICA-------CPMPYPSNNFALSCDLS-- 1833
FC S + TP+ C C +P P +C
Sbjct: 218 VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECR 277
Query: 1834 -ENGSLIS-----CNCQPGYGGARC-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
NG L C C PGY G RC E C G +G D + C+C+ +
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFG---------QDCAETCDCAPDAR-- 326
Query: 1887 DPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDAIFSKNCTA-CICDEFGMADCDST 1943
C NG CL C + G C LC GFYG +C A C CD C
Sbjct: 327 ----CFPANGACL-CEHGFTGDRCTDRLCPDGFYG-----LSCQAPCTCDREHSLSCHPM 376
Query: 1944 TGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTG 2003
G C C PG G C+ P G GC +C + C +G C+CA G TG
Sbjct: 377 NGECSCLPGWAGLHCNESCPQD---THGPGCQE-HC-LCLHGGVCQATSGLCQCAPGYTG 431
Query: 2004 KQC-DQCAAGFWNYTKDGCDHCNCNTGYSVG-----FMCN---ATGQCE--CLPGVIGEK 2052
C C Y + C+C + +C G C C PG G
Sbjct: 432 PHCASLCPPD--TYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFS 489
Query: 2053 CD---RCPERWVLIPQEGCLEC 2071
C+ +C V PQ G C
Sbjct: 490 CNASCQCAHEAVCSPQTGACTC 511
Score = 97.5 bits (232), Expect = 8e-19
Identities = 102/343 (29%), Positives = 130/343 (37%), Gaps = 44/343 (12%)
Query: 1736 CQCPRAYRGLSCEQ--CAEGHYRLPSGFCVPCQCNG-HSDQCDVNTGICLNCADNTIGDH 1792
C C + G C C +G Y L PC C+ HS C G C +C G H
Sbjct: 334 CLCEHGFTGDRCTDRLCPDGFYGLSCQ--APCTCDREHSLSCHPMNGEC-SCLPGWAGLH 390
Query: 1793 C-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG-YG-- 1848
C E C HG G CL C + + C G + C P YG
Sbjct: 391 CNESCPQDTHGP---GCQEHCL-CLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVN 446
Query: 1849 -GARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPG-SCDSINGDCLKCVNNTA 1906
ARC C P D + + + NCS P G SC++ + V +
Sbjct: 447 CSARCS-CENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQ 505
Query: 1907 GAACNLCAPGFYG--------DAIFSKNCTA-CICDEFGMADCDSTTGTCVCRPGVIGEK 1957
AC C PG++G F + C + C CD CD G C C+ G +G +
Sbjct: 506 TGACT-CTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSD--GCDPVHGRCQCQAGWMGAR 562
Query: 1958 CDRCAPDH-WGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWN 2015
C P+ WG+N CT N G C +NG C CA G G C + C G
Sbjct: 563 CHLSCPEGLWGVNCSNTCTCKNGGT------CLPENGNCVCAPGFRGPSCQRSCQPG--R 614
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
Y K C C C +S F + G C CL G G C + CP
Sbjct: 615 YGKR-CVPCKC-ANHS--FCHPSNGTCYCLAGWTGPDCSQPCP 653
Score = 93.5 bits (222), Expect = 1e-17
Identities = 78/312 (25%), Positives = 110/312 (35%), Gaps = 50/312 (16%)
Query: 227 IGGRCMCNG--HADTCEPADPAGNLNILV---CRCQHNT-CGPQCNKCCSGFEQKKWRIS 280
I G C+C C P G C+C H C PQ C +
Sbjct: 462 IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTC---------T 512
Query: 281 QNWDRFSCE-PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
W C+ PC C + D ++GR + CQ G C+
Sbjct: 513 PGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQ-------CQAGWMGARCHL 565
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYF 398
P W ++ C C + G C E+G C C P F+ P C SC G +
Sbjct: 566 SCPEGL------WG-VNCSNTCTCK---NGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY 615
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC-EICEDGYYSPEC-KNCECNTV 456
C PC C C P++G C C + G C + C G++ C + C+C+
Sbjct: 616 G-KRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG 670
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ 515
G+ C G C C ++G C + C G + +PC C C +G
Sbjct: 671 GT----CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEK----CHPETGA 722
Query: 516 CICKAGFGGPRC 527
C+C G G C
Sbjct: 723 CVCPPGHSGAPC 734
Score = 83.4 bits (197), Expect = 1e-14
Identities = 99/334 (29%), Positives = 134/334 (40%), Gaps = 66/334 (19%)
Query: 1749 QCAEGHYRLPSGFCVP-CQCNGHSDQCDVNTGICLNCADNTIGDHCEF-CMSGYHGDATV 1806
QC G Y GFCVP C +C V C C GD C C G G
Sbjct: 89 QCCHGFYE-SRGFCVPLCAQECVHGRC-VAPNQC-QCVPGWRGDDCSSECAPGMWG---- 141
Query: 1807 GTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC-EYCAAGYYGIPED 1865
P+ C+C NN SCD ++G C+C G C + C GYYG
Sbjct: 142 --PQCDKPCSC-----GNNS--SCD-PKSGV---CSCPSGLQPPNCLQPCTPGYYG---- 184
Query: 1866 TDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIF 1923
C+ C C G CD G C C G +C++ C+ G G F
Sbjct: 185 ------PACQFRCQCHG-------APCDPQTGACF-CPAERTGPSCDVSCSQGTSG--FF 228
Query: 1924 SKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHW-GLNTGLGCTPCNCGIA 1982
+ +C G+ + G+C C PG +G C P+ + G N C N G+
Sbjct: 229 CPSTHSC--QNGGVFQ--TPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGL- 283
Query: 1983 SESTQCDDDNGQCRCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMC-NATG 2040
CD GQCRCA G TG +C ++C G + +D + C+C + C A G
Sbjct: 284 -----CDRFTGQCRCAPGYTGDRCREECPVG--RFGQDCAETCDC----APDARCFPANG 332
Query: 2041 QCECLPGVIGEKC-DR-CPERWVLIPQEGCLECD 2072
C C G G++C DR CP+ + + + CD
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCD 366
Score = 77.0 bits (181), Expect = 1e-12
Identities = 57/200 (28%), Positives = 78/200 (39%), Gaps = 29/200 (14%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICD- 1395
PC CD S L C+ G+C C P G C+ +C +G P C+ C C +C
Sbjct: 362 PCTCDREHS--LSCHPMNGECSCLPGWAGLHCNESCPQDTHG-PGCQEHCLCLHGGVCQA 418
Query: 1396 DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
+G+C C G +C C P T+ + C+C N + C G+C C+
Sbjct: 419 TSGLCQCAPGYTGPHCASLCPPDTYGVNCSA---RCSCE------NAIACSPIDGECVCK 469
Query: 1455 EN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCK 1512
E RG C PG + F C C VC T C C G C C
Sbjct: 470 EGWQRGNCSVPCPPGTWGFSCNASCQCAHEA----VCSPQTGACTCTPGWHGAHCQLPCP 525
Query: 1513 EEYFNLQDDNPDGC-TKCFC 1531
+ F +GC ++C C
Sbjct: 526 KGQFG------EGCASRCDC 539
Score = 75.8 bits (178), Expect = 3e-12
Identities = 52/195 (26%), Positives = 69/195 (35%), Gaps = 23/195 (11%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAIC- 1394
A C CD C+ G+C C+ +G C +C G +G C C + C
Sbjct: 534 ASRCDCDHSDG----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCL 589
Query: 1395 DDNGMCICPKNVEGENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCAC 1453
+NG C+C G +C R C+P + + C C C N C +G C C
Sbjct: 590 PENGNCVCAPGFRGPSCQRSCQPGRYG----KRCVPCKC------ANHSFCHPSNGTCYC 639
Query: 1454 RENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTC 1511
G C C PGH+ C C+ GT C C C G C + C
Sbjct: 640 LAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCLEGC 695
Query: 1512 KEEYFNLQDDNPDGC 1526
F P C
Sbjct: 696 PLGTFGANCSQPCQC 710
Score = 72.1 bits (169), Expect = 3e-11
Identities = 54/181 (29%), Positives = 69/181 (38%), Gaps = 25/181 (13%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCR-PCHCPSTAICD 1395
+PC C S C+ G C C + C C GYYG P C+ C C
Sbjct: 146 KPCSCGNNSS----CDPKSGVCSCPSGLQPPNCLQPCTPGYYG-PACQFRCQCHGAPCDP 200
Query: 1396 DNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
G C CP G +CD C T F +C GV + G C+C
Sbjct: 201 QTGACFCPAERTGPSCDVSCSQGTSGFFCP---STHSCQNGGVF------QTPQGSCSCP 251
Query: 1455 ENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE 1513
G +C P + P+C Q C C+ G +CD+ T QC C G D C+E
Sbjct: 252 PGWMGTICSLPCPEGFHGPNCSQECRCHNGG----LCDRFTGQCRCAPGYTG---DRCRE 304
Query: 1514 E 1514
E
Sbjct: 305 E 305
Score = 71.7 bits (168), Expect = 5e-11
Identities = 49/162 (30%), Positives = 61/162 (37%), Gaps = 16/162 (9%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCRPCHCPSTAIC-DDNGMCICPKNVEGE 1409
C+ F GQC C P G C C G +G C C A C NG C+C G+
Sbjct: 284 CDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGD 343
Query: 1410 NC-DRCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C DR P F C C C+ + L C +G+C+C G C+ P
Sbjct: 344 RCTDRLCPDGF---YGLSCQAPCTCDR----EHSLSCHPMNGECSCLPGWAGLHCNESCP 396
Query: 1468 GHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
P C + C C HG VC + C C G C
Sbjct: 397 QDTHGPGCQEHCLC-LHG---GVCQATSGLCQCAPGYTGPHC 434
Score = 66.5 bits (155), Expect = 2e-09
Identities = 46/163 (28%), Positives = 54/163 (33%), Gaps = 16/163 (9%)
Query: 1349 ELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNV 1406
E C+ G C C P G C C G +G C C + CD +G C C
Sbjct: 499 EAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGW 558
Query: 1407 EGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-C 1465
G C P G NC+ N C ++G C C RG C C
Sbjct: 559 MGARCHLSCP--------EGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSC 610
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
PG Y C C C H C + CYC G C
Sbjct: 611 QPGRYG-KRCVPCKCANH----SFCHPSNGTCYCLAGWTGPDC 648
Score = 61.3 bits (142), Expect = 6e-08
Identities = 54/196 (27%), Positives = 73/196 (37%), Gaps = 28/196 (14%)
Query: 1358 QCPCKPNVIGRTCSA-CRTGYYGFPNC-RPCHCPSTAICD-DNGMCICPKNVEGENC-DR 1413
QC C P G CS+ C G +G P C +PC C + + CD +G+C CP ++ NC
Sbjct: 119 QCQCVPGWRGDDCSSECAPGMWG-PQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQP 177
Query: 1414 CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HCVPGHYAF 1472
C P + Q C C+ P C+ +G C C G CD C G F
Sbjct: 178 CTPGYYGPACQFRC-QCHGAP---------CDPQTGACFCPAERTGPSCDVSCSQGTSGF 227
Query: 1473 --PDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNPDGCTK- 1528
P + C ++G + C C G C C E + C
Sbjct: 228 FCPSTHSC---QNGGVFQT---PQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNG 281
Query: 1529 --CFCFGKTTRCSSSY 1542
C F RC+ Y
Sbjct: 282 GLCDRFTGQCRCAPGY 297
Score = 56.8 bits (131), Expect = 1e-06
Identities = 57/223 (25%), Positives = 79/223 (35%), Gaps = 36/223 (16%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
RC C+ H+D C+P C+CQ G +C+ C + W ++ + + +C+
Sbjct: 536 RCDCD-HSDGCDPVHGR-------CQCQAGWMGARCHLSCP---EGLWGVNCS-NTCTCK 583
Query: 290 PCN-CHNHTTECTYDPEIDEKRLSLDIN-GRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C C P GRY G +C+ C+ C+ T Y
Sbjct: 584 NGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY--GKRCVPCKCANHSF-CHPSNGTCYCL 640
Query: 348 YGKRWDELDVCQPCQ-----------CDPHFSTGNCEEESGRCECRPEFQPPDC-SSCAY 395
G W D QPC C H G C + G C C + C C
Sbjct: 641 AG--WTGPDCSQPCPPGHWGENCAQTCQCHHG-GTCHPQDGSCICPLGWTGHHCLEGCPL 697
Query: 396 GYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI 438
G F +PC C GE C P G C C ++G C I
Sbjct: 698 GTFGANCSQPCQCG----PGEKCHPETGACVCPPGHSGAPCRI 736
Score = 53.2 bits (122), Expect = 2e-05
Identities = 37/133 (27%), Positives = 50/133 (37%), Gaps = 16/133 (12%)
Query: 1333 YNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPST 1391
Y PC C + C+ G C C G CS C G++G + C C
Sbjct: 615 YGKRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG 670
Query: 1392 AICD-DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
C +G CICP G +C + C TF + + C C P G + C ++G
Sbjct: 671 GTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQ---PCQCGP----GEK--CHPETG 721
Query: 1450 KCACRENVRGRVC 1462
C C G C
Sbjct: 722 ACVCPPGHSGAPC 734
Score = 52.0 bits (119), Expect = 4e-05
Identities = 51/207 (24%), Positives = 72/207 (34%), Gaps = 31/207 (14%)
Query: 1338 RPCLCDFMG-STELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP----CHCPSTA 1392
+PC + G + + C G PC P C A RTG +C CPST
Sbjct: 176 QPCTPGYYGPACQFRCQCHGA--PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTH 233
Query: 1393 ICDDNGM-------CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C + G+ C CP G C P F +C C+ G+ C+
Sbjct: 234 SCQNGGVFQTPQGSCSCPPGWMGTICSL--PCPEGFHGPNCSQECRCHNGGL------CD 285
Query: 1446 ADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+G+C C G C + C G + DC + C C C C C+
Sbjct: 286 RFTGQCRCAPGYTGDRCREECPVGRFG-QDCAETCDCAPDAR----CFPANGACLCEHGF 340
Query: 1504 RGQACD--TCKEEYFNLQDDNPDGCTK 1528
G C C + ++ L P C +
Sbjct: 341 TGDRCTDRLCPDGFYGLSCQAPCTCDR 367
Score = 36.7 bits (81), Expect = 1.6
Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 6/99 (6%)
Query: 699 GTLNSLGACNTKSGQ-CVCKQHVGERQCDQCLDGFYR--LQTNDVFGCTECDCDIGGSID 755
G S G C Q CV + V QC QC+ G+ + G CD S
Sbjct: 93 GFYESRGFCVPLCAQECVHGRCVAPNQC-QCVPGWRGDDCSSECAPGMWGPQCDKPCSCG 151
Query: 756 NN--CDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQFQ 792
NN CD +G C C S ++ C QP Y+ QF+
Sbjct: 152 NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR 190
>AL138836-3|CAC22313.2| 602|Homo sapiens multiple EGF-like-domains
9 protein.
Length = 602
Score = 153 bits (372), Expect = 9e-36
Identities = 83/248 (33%), Positives = 123/248 (49%), Gaps = 22/248 (8%)
Query: 497 CNCDTSGT-EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGS 555
CNC G+ + C+ +GQC C+ G+ G C+ C G+Y+ C PC+C P G+
Sbjct: 204 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSG--LCQPCDCSPHGA 261
Query: 556 TSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP--DCLSCNCDVSGSIGSTCDD-NGLC- 611
S C++ GKC C G+ CD+C GYY + CL C C+ + ++CD G C
Sbjct: 262 LSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCN---NRSASCDALTGACL 318
Query: 612 HCKSNFDGAKCDTCREQFYNYP-ACEECNCDPRGVTASFAGCGSVPAGEL---C-QCKDR 666
+C+ N G C+ C+E FY P A +EC P S C S+ + EL C QCKD
Sbjct: 319 NCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSC-SIKSSELEPECDQCKDG 377
Query: 667 VQGRICNDCKPLYWNLQEYNPFGCEQCNCN-LAGTLNSLGACNTKSGQCV-CKQHVGERQ 724
G CN C+ Y+N C +C C+ + + C +SG+C+ C +
Sbjct: 378 YIGPNCNKCENGYYNFDSI----CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFW 433
Query: 725 CDQCLDGF 732
C+ CL+G+
Sbjct: 434 CENCLEGY 441
Score = 144 bits (348), Expect = 7e-33
Identities = 84/245 (34%), Positives = 118/245 (48%), Gaps = 23/245 (9%)
Query: 357 VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYG-YFDYPN--CKPCTCNLNGT 413
VC C + C + +G+CECRP +Q C +C G Y +Y + C+PC C+ +G
Sbjct: 203 VCN-CSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGA 261
Query: 414 EGEHCTPTDGLCPCKYNYAGKSCEICEDGYY---SPECKNCECNTVGSVSYVCDKLTGDC 470
C + G C CK G C+ C+DGYY C C+CN + S CD LTG C
Sbjct: 262 LSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCN---NRSASCDALTGAC 317
Query: 471 -TCKSKYSGRTCNQCQAGYYNYPTCK------PCNCDTSGTEPSI-CDDVSGQC-ICKAG 521
C+ G C +C+ G+Y P PC+ TS SI ++ +C CK G
Sbjct: 318 LNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDG 377
Query: 522 FGGPRCDQCLSGYY-MQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQ 579
+ GP C++C +GYY + R+ QC + DP + G+C NCL N G C+
Sbjct: 378 YIGPNCNKCENGYYNFDSICRKCQC-HGHVDPVKTPKICKPESGECINCLHNTTGFWCEN 436
Query: 580 CSPGY 584
C GY
Sbjct: 437 CLEGY 441
Score = 144 bits (348), Expect = 7e-33
Identities = 85/247 (34%), Positives = 117/247 (47%), Gaps = 28/247 (11%)
Query: 312 SLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN 371
SL++N + G+C C+ +G++C C+ +Y Y +CQPC C PH +
Sbjct: 211 SLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTS-----GLCQPCDCSPHGALSI 264
Query: 372 CEEESGRCECRPEFQPPDCSSCAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLC-PCK 428
SG+C+C+ C C GY+ + C PC CN C G C C+
Sbjct: 265 PCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCN---NRSASCDALTGACLNCQ 321
Query: 429 YNYAGKSCEICEDGYY-SP----ECKNCECNTV---GSVSYVCDKLTGDC-TCKSKYSGR 479
N G CE C++G+Y SP EC C C+ V GS S +L +C CK Y G
Sbjct: 322 ENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGP 381
Query: 480 TCNQCQAGYYNYPT-CKPCNC----DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSG 533
CN+C+ GYYN+ + C+ C C D T P IC SG+CI C G C+ CL G
Sbjct: 382 NCNKCENGYYNFDSICRKCQCHGHVDPVKT-PKICKPESGECINCLHNTTGFWCENCLEG 440
Query: 534 YYMQVLG 540
Y + G
Sbjct: 441 YVHDLEG 447
Score = 137 bits (331), Expect = 8e-31
Identities = 63/188 (33%), Positives = 93/188 (49%), Gaps = 16/188 (8%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+CQC G C++C +G+Y C+PCQCN S CD TG CLNC +N+ G+HCE
Sbjct: 271 KCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCE 330
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCN-CQPGYGGARCE 1853
C G++ + ++CL C C + SC + + C+ C+ GY G C
Sbjct: 331 ECKEGFY--QSPDATKECLRCPCSAVTSTG----SCSIKSSELEPECDQCKDGYIGPNCN 384
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP-QDPGSCDSINGDCLKCVNNTAGAACNL 1912
C GYY C+ C C G+++P + P C +G+C+ C++NT G C
Sbjct: 385 KCENGYYNF--------DSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCEN 436
Query: 1913 CAPGFYGD 1920
C G+ D
Sbjct: 437 CLEGYVHD 444
Score = 118 bits (283), Expect = 5e-25
Identities = 69/211 (32%), Positives = 98/211 (46%), Gaps = 27/211 (12%)
Query: 1340 CLCDFMGSTELE-CNTFGGQCPCKPNVIGRTCSACRTGYY-GFPN--CRPCHC-PSTAI- 1393
C C +GS + CN GQC C+P G C C+ G+Y + + C+PC C P A+
Sbjct: 204 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 263
Query: 1394 --CDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ +G C C V G CDRC+ + F + GC C CN C+A +G C
Sbjct: 264 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFS-KNGCLPCQCN-----NRSASCDALTGAC 317
Query: 1452 A-CRENVRGRVCDHCVPGHYAFPD----CYQCTCNRHGTTYDVCDQNT---AQC-YCKTN 1502
C+EN +G C+ C G Y PD C +C C+ +T +++ +C CK
Sbjct: 318 LNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDG 377
Query: 1503 VRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
G C+ C+ Y+N C KC C G
Sbjct: 378 YIGPNCNKCENGYYNFDSI----CRKCQCHG 404
Score = 114 bits (275), Expect = 5e-24
Identities = 70/222 (31%), Positives = 103/222 (46%), Gaps = 16/222 (7%)
Query: 1316 PNETGL-CREAMFSITSEYNSG-ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
P GL C Y SG +PC C G+ + CN+ G+C CK VIG C C
Sbjct: 228 PGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRC 286
Query: 1374 RTGYYGFP--NCRPCHCPS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNF-DVQRGC 1427
+ GYYGF C PC C + +A CD G C+ C +N +G +C+ CK + D + C
Sbjct: 287 QDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKEC 346
Query: 1428 DDCNCNPLGVVGN-QLQCEADSGKC-ACRENVRGRVCDHCVPGHYAFPD-CYQCTCNRH- 1483
C C+ + G+ ++ +C C++ G C+ C G+Y F C +C C+ H
Sbjct: 347 LRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHV 406
Query: 1484 --GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEYFNLQDDN 1522
T +C + +C C N G C+ C E Y + + N
Sbjct: 407 DPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGN 448
Score = 111 bits (268), Expect = 3e-23
Identities = 74/261 (28%), Positives = 110/261 (42%), Gaps = 37/261 (14%)
Query: 1772 DQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD 1831
++C+ TG C C G HCE C G++ + T G C C C S + ALS
Sbjct: 215 NRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGL---CQPCDC-----SPHGALSIP 265
Query: 1832 LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC 1891
+ +G C C+ G G+ C+ C GYYG ++ C PC C+ SC
Sbjct: 266 CNSSGK---CQCKVGVIGSICDRCQDGYYGFSKNG-------CLPCQCNNR-----SASC 310
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF-GMADCDSTTG----T 1946
D++ G CL C N+ G C C GFY +K C C C C +
Sbjct: 311 DALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPE 370
Query: 1947 C-VCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ----CDDDNGQC-RCAKG 2000
C C+ G IG C++C ++ ++ C C C + + C ++G+C C
Sbjct: 371 CDQCKDGYIGPNCNKCENGYYNFDS--ICRKCQCHGHVDPVKTPKICKPESGECINCLHN 428
Query: 2001 VTGKQCDQCAAGFWNYTKDGC 2021
TG C+ C G+ + + C
Sbjct: 429 TTGFWCENCLEGYVHDLEGNC 449
Score = 111 bits (266), Expect = 6e-23
Identities = 80/243 (32%), Positives = 101/243 (41%), Gaps = 44/243 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGH---SDQCDVNTGICLNCADNTIG 1790
+C+C Y+GL CE C EG Y SG C PC C+ H S C+ ++G C C IG
Sbjct: 223 QCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCN-SSGKC-QCKVGVIG 280
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C GY+G + G CL C C NN + SCD L NCQ G
Sbjct: 281 SICDRCQDGYYGFSKNG----CLPCQC------NNRSASCDALTGACL---NCQENSKGN 327
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC----DSINGDCLKCVNNTA 1906
CE C G+Y P+ T C C CS GSC + +C +C +
Sbjct: 328 HCEECKEGFYQSPDAT-----KECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYI 379
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMAD-------CDSTTGTCV-CRPGVIGEKC 1958
G CN C G+Y F C C C G D C +G C+ C G C
Sbjct: 380 GPNCNKCENGYYN---FDSICRKCQC--HGHVDPVKTPKICKPESGECINCLHNTTGFWC 434
Query: 1959 DRC 1961
+ C
Sbjct: 435 ENC 437
Score = 102 bits (244), Expect = 3e-20
Identities = 62/192 (32%), Positives = 94/192 (48%), Gaps = 28/192 (14%)
Query: 593 CNCDVSGSIG-STCDDN-GLCHCKSNFDGAKCDTCREQFY-NYPA--CEECNCDPRGVTA 647
CNC V GS+ + C+ G C C+ + G C+TC+E FY NY + C+ C+C P G +
Sbjct: 204 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 263
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
C S +G+ CQCK V G IC+ C+ Y+ ++ GC C CN N +C
Sbjct: 264 --IPCNS--SGK-CQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCN-----NRSASC 310
Query: 708 NTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCH 766
+ +G C+ C+++ C++C +GFY+ + C C C + +TG C
Sbjct: 311 DALTGACLNCQENSKGNHCEECKEGFYQ-SPDATKECLRCPC--------SAVTSTGSCS 361
Query: 767 CHSRVEGRRCDQ 778
S CDQ
Sbjct: 362 IKSSELEPECDQ 373
Score = 101 bits (241), Expect = 6e-20
Identities = 62/203 (30%), Positives = 91/203 (44%), Gaps = 24/203 (11%)
Query: 1877 CNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG 1936
CNCS + + C+ G C +C G C C GFY + S C C C G
Sbjct: 204 CNCSV-VGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYT-SGLCQPCDCSPHG 260
Query: 1937 MAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQ 1994
C+S+ G C C+ GVIG CDRC ++G + GC PC C + S CD G
Sbjct: 261 ALSIPCNSS-GKCQCKVGVIGSICDRCQDGYYGFSKN-GCLPCQCN--NRSASCDALTGA 316
Query: 1995 C-RCAKGVTGKQCDQCAAGFW---NYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
C C + G C++C GF+ + TK+ C C C+ +TG C +
Sbjct: 317 CLNCQENSKGNHCEECKEGFYQSPDATKE-CLRCPCSA-------VTSTGSCSIKSSELE 368
Query: 2051 EKCDRCPERWVLIPQEGCLECDS 2073
+CD+C + ++ C +C++
Sbjct: 369 PECDQCKDGYI---GPNCNKCEN 388
Score = 95.5 bits (227), Expect = 3e-18
Identities = 72/249 (28%), Positives = 106/249 (42%), Gaps = 40/249 (16%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
C C+PGY G CE C G+Y +T C+PC+CS + P C+S +G C +
Sbjct: 224 CECRPGYQGLHCETCKEGFYLN------YTSGLCQPCDCSPHGALSIP--CNS-SGKC-Q 273
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV-CRPGVIGEKC 1958
C G+ C+ C G+YG FSKN C C C+ A CD+ TG C+ C+ G C
Sbjct: 274 CKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS-ASCDALTGACLNCQENSKGNHC 329
Query: 1959 DRCAPDHW-GLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGF---- 2013
+ C + + C C C + + G C +CDQC G+
Sbjct: 330 EECKEGFYQSPDATKECLRCPCSAVTST-------GSCSIKSSELEPECDQCKDGYIGPN 382
Query: 2014 WNYTKDG-------CDHCNCN---TGYSVGFMCN-ATGQC-ECLPGVIGEKCDRCPERWV 2061
N ++G C C C+ +C +G+C CL G C+ C E +V
Sbjct: 383 CNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYV 442
Query: 2062 LIPQEGCLE 2070
+ C++
Sbjct: 443 HDLEGNCIK 451
Score = 91.5 bits (217), Expect = 5e-17
Identities = 64/231 (27%), Positives = 100/231 (43%), Gaps = 45/231 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C+ H P + +G C+C+ G C++C G+ + S+N C P
Sbjct: 254 CDCSPHGALSIPCNSSGK-----CQCKVGVIGSICDRCQDGY----YGFSKN----GCLP 300
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+N + C +L G CLNCQ N++G +C +C+ +Y+
Sbjct: 301 CQCNNRSASCD----------ALT--------GACLNCQENSKGNHCEECKEGFYQSP-- 340
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCE-----CRPEFQPPDCSSCAYGYFDYPN-CK 404
D C C C STG+C +S E C+ + P+C+ C GY+++ + C+
Sbjct: 341 --DATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICR 398
Query: 405 PCTCNLNGTEGEH---CTPTDGLC-PCKYNYAGKSCEICEDGYYSPECKNC 451
C C+ + + C P G C C +N G CE C +GY NC
Sbjct: 399 KCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNC 449
Score = 88.2 bits (209), Expect = 5e-16
Identities = 69/250 (27%), Positives = 104/250 (41%), Gaps = 47/250 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C C+ G C C GF N+ C+PC+C H LS+
Sbjct: 224 CECRPGYQGLHCETCKEGFYL-------NYTSGLCQPCDCSPHGA------------LSI 264
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
N GKC C+ G C++C+ YY + K + C PCQC+ + +C+
Sbjct: 265 PCN----SSGKC-QCKVGVIGSICDRCQDGYY-GFSK-----NGCLPCQCNNR--SASCD 311
Query: 374 EESGRC-ECRPEFQPPDCSSCAYGYFDYPN----CKPCTCNLNGTEGEHCTPTDGLCP-- 426
+G C C+ + C C G++ P+ C C C+ + G + L P
Sbjct: 312 ALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPEC 371
Query: 427 --CKYNYAGKSCEICEDGYYSPE--CKNCECN-TVGSVS--YVCDKLTGDC-TCKSKYSG 478
CK Y G +C CE+GYY+ + C+ C+C+ V V +C +G+C C +G
Sbjct: 372 DQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTG 431
Query: 479 RTCNQCQAGY 488
C C GY
Sbjct: 432 FWCENCLEGY 441
Score = 68.9 bits (161), Expect = 3e-10
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 4/92 (4%)
Query: 693 CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGG 752
CNC++ G+LN + CN +GQC C+ C+ C +GFY T+ + C CDC G
Sbjct: 204 CNCSVVGSLN-VNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL--CQPCDCSPHG 260
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
++ C+ ++G+C C V G CD+ +Y
Sbjct: 261 ALSIPCN-SSGKCQCKVGVIGSICDRCQDGYY 291
Score = 51.2 bits (117), Expect = 7e-05
Identities = 34/115 (29%), Positives = 45/115 (39%), Gaps = 21/115 (18%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
RC C+ T + + L +C+ GP CNKC +G+ N+D C
Sbjct: 348 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY--------YNFDSI-CR 398
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C CH H DP K + G+C+NC HNT G C C Y
Sbjct: 399 KCQCHGHV-----DPVKTPKICKPE-------SGECINCLHNTTGFWCENCLEGY 441
Score = 42.7 bits (96), Expect = 0.024
Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 1473 PDCYQCTCNRHGT-TYDVCDQNTAQCYCKTNVRGQACDTCKEEYF 1516
P Y C C+ G+ + C+Q T QC C+ +G C+TCKE ++
Sbjct: 199 PPEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY 243
>BC013591-1|AAH13591.2| 469|Homo sapiens NTN4 protein protein.
Length = 469
Score = 151 bits (366), Expect = 5e-35
Identities = 91/305 (29%), Positives = 139/305 (45%), Gaps = 37/305 (12%)
Query: 125 DCERYFGKESLQPITKDDSVICSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQEW 184
+C FG E + K + IC+++YS P GE+ L+ + +++ V QE
Sbjct: 4 NCSATFGLED--DVVKKGA-ICTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKV-QEQ 59
Query: 185 TRATNVRLRLLRTKNLLGHLMSVARQDPTVTRRYF--YSIKDISIGGRCMCNGHADTC-- 240
+ TN+R++LL+ ++ R D ++F Y+I D + G C CNGHAD C
Sbjct: 60 LKITNLRVQLLKRQSC-----PCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIP 114
Query: 241 ----EPADPAGNLNIL--VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF--SCEPCN 292
P G +++ C C+HNT G C C + + W + C C
Sbjct: 115 VHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCK 174
Query: 293 CHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRW 352
C+ H C +D + E +G GG C +CQHNTEG C +C+P +YR + +
Sbjct: 175 CNGHADTCHFDVNVWEA------SGN-RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPF 227
Query: 353 DELDVCQPCQCDPHFST---GN----CEEESGRCECRPEFQPPDCSSCAYGYFDYPN--C 403
D C+PC C P S N C+ +G C C+P C C GY+ + + C
Sbjct: 228 SAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGC 287
Query: 404 KPCTC 408
+PC C
Sbjct: 288 RPCDC 292
Score = 99.5 bits (237), Expect = 2e-19
Identities = 61/176 (34%), Positives = 78/176 (44%), Gaps = 27/176 (15%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP-EDTDLHTG--DYCKPCNCSGNINPQD------PGSC 1891
C C+ G+ C++CA Y P E D TG + C+ C C+G+ + S
Sbjct: 134 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 193
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAI--FSKN--CTACICDEFGMAD-------- 1939
+ G C C +NT G C C PGFY D FS C C C G A
Sbjct: 194 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 253
Query: 1940 CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC 1995
CD + G C C+PGV G +CDRC +WG GC PC+C + CD G C
Sbjct: 254 CDPSNGDCPCKPGVAGRRCDRCMVGYWGFG-DYGCRPCDC-----AGSCDPITGDC 303
Score = 96.7 bits (230), Expect = 1e-18
Identities = 69/203 (33%), Positives = 96/203 (47%), Gaps = 42/203 (20%)
Query: 1716 GVDYYMGDELVVRRATSVEECQ-CPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC 1774
G + + + + + T+ CQ C Y E A+G P+ C C+CNGH+D C
Sbjct: 125 GTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWE-AADGKTGAPNE-CRTCKCNGHADTC 182
Query: 1775 --DVNT---------GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICAC-PM- 1819
DVN G+C +C NT G +C+ C G++ D P C C+C P+
Sbjct: 183 HFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVG 242
Query: 1820 --PYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDY-CKP 1876
P+N+ CD S NG C C+PG G RC+ C GY+G GDY C+P
Sbjct: 243 SAVLPANSVTF-CDPS-NG---DCPCKPGVAGRRCDRCMVGYWGF--------GDYGCRP 289
Query: 1877 CNCSGNINPQDPGSCDSINGDCL 1899
C+C+ GSCD I GDC+
Sbjct: 290 CDCA--------GSCDPITGDCI 304
Score = 82.6 bits (195), Expect = 2e-14
Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 33/182 (18%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP------------ACEECNCDPRGVTASF-----A 650
+G C CK N G+ C C + + P C C C+ T F
Sbjct: 131 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE 190
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP-LYWNLQE--YNPFGCEQCNCNLAGTL----NS 703
G+ G C+ +G+ C CKP Y +L+ P C+ C+C+ G+ NS
Sbjct: 191 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 250
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
+ C+ +G C CK V R+CD+C+ G++ +GC CDC GS CD TG
Sbjct: 251 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDC--AGS----CDPITG 301
Query: 764 QC 765
C
Sbjct: 302 DC 303
Score = 81.8 bits (193), Expect = 4e-14
Identities = 52/171 (30%), Positives = 75/171 (43%), Gaps = 34/171 (19%)
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFS---------KNCTACICD----- 1933
PG+ ++G C+ C +NTAG+ C CAP Y D + C C C+
Sbjct: 124 PGTFHMVHGKCM-CKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRTCKCNGHADT 181
Query: 1934 -EFGM----ADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCGI- 1981
F + A + + G C C+ G+ C RC P + + C PC+C
Sbjct: 182 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 241
Query: 1982 ------ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNC 2026
A+ T CD NG C C GV G++CD+C G+W + GC C+C
Sbjct: 242 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 292
Score = 80.6 bits (190), Expect = 1e-13
Identities = 60/202 (29%), Positives = 85/202 (42%), Gaps = 47/202 (23%)
Query: 356 DVCQPCQ-CDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP------------N 402
D C P P + G G+C C+ C CA Y D P
Sbjct: 110 DQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNE 169
Query: 403 CKPCTCN---------LNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGYY-------- 444
C+ C CN +N E + G+C C++N G+ C+ C+ G+Y
Sbjct: 170 CRTCKCNGHADTCHFDVNVWEASG-NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 228
Query: 445 SPE-CKNCECNTVGSVSY------VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CK 495
+P+ CK C C+ VGS CD GDC CK +GR C++C GY+ + C+
Sbjct: 229 APDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCR 288
Query: 496 PCNCDTSGTEPSICDDVSGQCI 517
PC+C S CD ++G CI
Sbjct: 289 PCDCAGS------CDPITGDCI 304
Score = 77.0 bits (181), Expect = 1e-12
Identities = 60/209 (28%), Positives = 84/209 (40%), Gaps = 44/209 (21%)
Query: 540 GRERQCVPCN-CDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP---------- 588
G QC+P + P + T GKC C N G+ C C+P Y P
Sbjct: 107 GHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGA 166
Query: 589 --DCLSCNC---------DVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFY------ 630
+C +C C DV+ S G+C C+ N +G C C+ FY
Sbjct: 167 PNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRP 226
Query: 631 -NYP-ACEECNCDPRGVTASFAGCGSV--PAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
+ P AC+ C+C P G A + P+ C CK V GR C+ C YW +Y
Sbjct: 227 FSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY- 285
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCV 715
GC C+C G+C+ +G C+
Sbjct: 286 --GCRPCDC--------AGSCDPITGDCI 304
Score = 77.0 bits (181), Expect = 1e-12
Identities = 58/177 (32%), Positives = 75/177 (42%), Gaps = 41/177 (23%)
Query: 1357 GQCPCKPNVIGRTCSAC-----------RTGYYGFPN-CRPCHC---PSTAICDDN---- 1397
G+C CK N G C C G G PN CR C C T D N
Sbjct: 132 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 191
Query: 1398 ------GMC-ICPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLG---VVGNQL 1442
G+C C N EG+ C RCKP + F C C+C+P+G + N +
Sbjct: 192 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 251
Query: 1443 Q-CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTYDVCDQNTAQC 1497
C+ +G C C+ V GR CD C+ G++ F D Y C C+ G+ CD T C
Sbjct: 252 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD-YGCRPCDCAGS----CDPITGDC 303
Score = 71.7 bits (168), Expect = 5e-11
Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 39/164 (23%)
Query: 423 GLCPCKYNYAGKSCEICEDGYY------------SP-ECKNCECNTVGSVSYVC------ 463
G C CK+N AG C+ C Y +P EC+ C+CN +
Sbjct: 132 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 191
Query: 464 --DKLTGDCT-CKSKYSGRTCNQCQAGYY-------NYP-TCKPCNCDTSGT------EP 506
++ G C C+ G+ C +C+ G+Y + P CKPC+C G+
Sbjct: 192 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 251
Query: 507 SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
+ CD +G C CK G G RCD+C+ GY+ G + C PC+C
Sbjct: 252 TFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFG-DYGCRPCDC 292
Score = 68.1 bits (159), Expect = 6e-10
Identities = 60/208 (28%), Positives = 79/208 (37%), Gaps = 38/208 (18%)
Query: 1384 RPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFN-----FDVQRG----CDDCNCNP 1434
RP P T +G C+C N G +C C P + D + G C C CN
Sbjct: 119 RPVKAPGTFHMV-HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNG 177
Query: 1435 ------LGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHY-------AFPD-CYQCT 1479
V + G C C+ N G+ C C PG Y + PD C C+
Sbjct: 178 HADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCS 237
Query: 1480 CNRHGT------TYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFG 1533
C+ G+ + CD + C CK V G+ CD C Y+ D GC C C G
Sbjct: 238 CHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDCAG 294
Query: 1534 K----TTRCSSSYYTWAAIDEMVDWYPV 1557
T C SS+ E+ D+ PV
Sbjct: 295 SCDPITGDCISSHTDIDWYHEVPDFRPV 322
Score = 63.7 bits (148), Expect = 1e-08
Identities = 34/73 (46%), Positives = 39/73 (53%), Gaps = 11/73 (15%)
Query: 1338 RPCLCDFMGSTELECN--TF----GGQCPCKPNVIGRTCSACRTGYYGFPN--CRPCHCP 1389
+PC C +GS L N TF G CPCKP V GR C C GY+GF + CRPC C
Sbjct: 234 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCA 293
Query: 1390 STAICDD-NGMCI 1401
+ CD G CI
Sbjct: 294 GS--CDPITGDCI 304
Score = 62.5 bits (145), Expect = 3e-08
Identities = 60/219 (27%), Positives = 88/219 (40%), Gaps = 28/219 (12%)
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
Y +D+ C CN + C P G P K A + + +C C+ N
Sbjct: 92 YAIYDFIVKGSCFCN---GHADQCIPVHGFRPVK---APGTFHMVHG-----KCM-CKHN 139
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPTCKPCNCDTSGTEPSICDDV 512
T GS C L D ++ G+T N+C+ N C+ D + E S +
Sbjct: 140 TAGSHCQHCAPLYNDRPWEAA-DGKTGAPNECRTCKCN-GHADTCHFDVNVWEAS-GNRS 196
Query: 513 SGQCI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGS------TSTSCS- 561
G C C+ G C +C G+Y + C PC+C P GS + T C
Sbjct: 197 GGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDP 256
Query: 562 ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS 600
++G C C G +CD+C GY+ + D CD +GS
Sbjct: 257 SNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGS 295
Score = 61.3 bits (142), Expect = 6e-08
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 32/160 (20%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDH----WGLNTGLG-----CTPCNCGIASESTQCDDD---- 1991
G C+C+ G C CAP + W G C C C +++ D +
Sbjct: 132 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 191
Query: 1992 -----NGQCR-CAKGVTGKQCDQCAAGFWNYTK------DGCDHCNCNT-------GYSV 2032
G C C G+ C +C GF+ + D C C+C+ SV
Sbjct: 192 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 251
Query: 2033 GFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECD 2072
F + G C C PGV G +CDRC + GC CD
Sbjct: 252 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCD 291
Score = 60.1 bits (139), Expect = 1e-07
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 34/163 (20%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQ-------VLGRERQCVPCNCDPTGST-------- 556
V G+C+CK G C C Y + G +C C C+ T
Sbjct: 130 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 189
Query: 557 -STSCSADGKC-NCLTNFGGAQCDQCSPGYYK-------YPD-CLSCNCDVSGSI----- 601
++ + G C +C N G C +C PG+Y+ PD C C+C GS
Sbjct: 190 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 249
Query: 602 -GSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
+ CD NG C CK G +CD C ++ + C C+C
Sbjct: 250 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 292
Score = 59.3 bits (137), Expect = 3e-07
Identities = 49/141 (34%), Positives = 56/141 (39%), Gaps = 23/141 (16%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEYN---PFGCEQCNCN-LAGT----LNSLGACN 708
C CK G C C PLY W + P C C CN A T +N A
Sbjct: 134 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 193
Query: 709 TKSGQ-CVCKQHVGERQ-CDQCLDGFYRLQTNDVFG---CTECDCDIGGS--IDNN---- 757
+SG C QH E Q C +C GFYR C C C GS + N
Sbjct: 194 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 253
Query: 758 CDKTTGQCHCHSRVEGRRCDQ 778
CD + G C C V GRRCD+
Sbjct: 254 CDPSNGDCPCKPGVAGRRCDR 274
Score = 38.3 bits (85), Expect = 0.52
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN 1783
+C C G C++C G++ C PC C G CD TG C++
Sbjct: 260 DCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG---SCDPITGDCIS 305
>AY327114-1|AAQ72569.1| 1668|Homo sapiens laminin alpha 3 splice
variant a protein.
Length = 1668
Score = 148 bits (359), Expect = 3e-34
Identities = 70/154 (45%), Positives = 95/154 (61%), Gaps = 19/154 (12%)
Query: 1750 CAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
C+ G+YR L +G CVPC CNGHS+QC +GIC+NC NT G+HCE C GY+G+A
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPED 1865
G+ R ACP P+ +N+FA C + NG + C+C+ GY G +CE CA GY+G P+
Sbjct: 119 HGSCR-----ACPCPH-TNSFATGCVV--NGGDVRCSCKAGYTGTQCERCAPGYFGNPQ- 169
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL 1899
G C+PC+C+ N GSC + GDC+
Sbjct: 170 ---KFGGSCQPCSCNSN---GQLGSCHPLTGDCI 197
Score = 125 bits (301), Expect = 3e-27
Identities = 153/764 (20%), Positives = 312/764 (40%), Gaps = 66/764 (8%)
Query: 2387 LTSEATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXX 2446
L EA HA L+ A L E+ + + + I
Sbjct: 473 LVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAA 532
Query: 2447 XXXXNV--TKLNRILDERVRPARERSSSLLADATKAQHAVDQKLLPNLTATEEVLRKIRD 2504
+ T + L + + S LL +A Q + Q++ P L ++ L +
Sbjct: 533 SASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTV 592
Query: 2505 HLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRVNATIGTTFSVMSHLGPELATSKDWA 2563
D + ++ + A V T V+ L P +
Sbjct: 593 QKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIK 652
Query: 2564 QTLPKLADEG-QKMTSNVESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKL 2622
T + +E +K ++ ++ + + + P + ++ + ++
Sbjct: 653 DTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISD----NMDRI 708
Query: 2623 KDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR---TKEKDG--- 2676
++L++QAR A+++ V + F+ S ++ RLP+ ++++ T +S + + ++E G
Sbjct: 709 RELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTEN 768
Query: 2677 -FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADN 2735
F++YLGN + S DY+ + + +G V ++GD A + +D+++ +
Sbjct: 769 MFVMYLGN-------KDASRDYIGMAVVDGQLTCVYNLGDRE------AELQVDQILTKS 815
Query: 2736 RWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA---DLPGH--HTIFNLDKEKSKLYV 2789
+ ++DR+ +R+ R + G + + D+ G +T+ NLD E YV
Sbjct: 816 ETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYV 875
Query: 2790 GGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGPQ 2848
GG P D KL +SFP ++G IE + + + L+NF L + +
Sbjct: 876 GGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDK 935
Query: 2849 EYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYL 2907
Y F+G GYA + + + P Q + +T GL++ G F SL ++DG++ +
Sbjct: 936 NY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVDRGLLFFAENGDRFISLNIEDGKLMV 991
Query: 2908 QVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLD 2967
+ L N+E G A N+G+ H + + + + ++ +V ++ ++
Sbjct: 992 RYKL-NSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDV---QNTIIDGEVFDFS 1047
Query: 2968 TMNFGGNNKGI---LQVPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC----QFASL 3020
T GG I + F GCM+ + + L+ +++G+ C +
Sbjct: 1048 TYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLN---DTVGVTKKCSEDWKLVRS 1104
Query: 3021 VSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVN 3077
SF+ L F D+ +++ Q + F+T +P+G+L + + T+ ++ ++L +
Sbjct: 1105 ASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTR------NLQVTLED 1157
Query: 3078 G--KLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD 3119
G +L + TY D H ++V + S L+L++DD
Sbjct: 1158 GYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDD 1201
Score = 104 bits (249), Expect = 7e-21
Identities = 89/363 (24%), Positives = 160/363 (44%), Gaps = 24/363 (6%)
Query: 3309 RFGSRNVSRIEYAKLPGRQLEG-FDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
+FG S + + KLP L+ + +T +G ++F+ + KN F+A ++
Sbjct: 1323 QFGDIPTSHLLF-KLPQELLKPRSQFAVDMQTTSSRG-LVFHTGT---KN--SFMALYLS 1375
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPL 3427
+L + G+ I S ND WHTV +G G+L VD E S+ N+ +
Sbjct: 1376 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 1435
Query: 3428 SLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN-I 3486
S+ P Y G + + + N F+GCLK ++ + + ++ C+ +
Sbjct: 1436 SIRAPVYLGS--PPSGKPKSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 1490
Query: 3487 EDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK-DYMVLELL 3545
E G+YF + ++ L + +G E + +RPR+ TG+L+ + + ++ + L
Sbjct: 1491 EKGIYF----SEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1546
Query: 3546 DSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFS-KPGIGA 3604
+V A++++G G + ++ K LCDG WH + D S G
Sbjct: 1547 AGKVTASMDSGAG--GTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIP 1604
Query: 3605 YTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRG-AHVG 3663
+ T L++GG + +R + + F GC+RNI V PV V + +G +
Sbjct: 1605 FPPASTQEPLHLGGAPANLTTLR-IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 1663
Query: 3664 VCP 3666
CP
Sbjct: 1664 GCP 1666
Score = 102 bits (245), Expect = 2e-20
Identities = 95/392 (24%), Positives = 159/392 (40%), Gaps = 27/392 (6%)
Query: 1913 CAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWGLN 1969
C+PG+Y D +++ C C C+ C +G CV C+ GE C+RC ++G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
Query: 1970 TGLGCTPCNCGIASE-STQCDDDNG--QCRCAKGVTGKQCDQCAAG-FWNYTKDG--CDH 2023
C C C + +T C + G +C C G TG QC++CA G F N K G C
Sbjct: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
Query: 2024 CNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDALIFSVE 2083
C+CN+ +G TG C + E D P E C +CDSC L+ +
Sbjct: 178 CSCNSNGQLGSCHPLTGDC-----INQEPKDSS-------PAEECDDCDSCVMTLLNDLA 225
Query: 2084 DLSALLANETMDFKDKADSFFTTQRLNYISNQTELLRPKVAQLKTVDIGEVTSSIKTLET 2143
+ L + + S +++ ++ Q + LR ++ ++ I S I+ LE
Sbjct: 226 TMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA-ISNHGSKIEGLER 284
Query: 2144 SAKNLLRSAEFAATDSDKQISRAAKLAEDAERTLAAVRESAREATEVVKHVADLATGLEL 2203
+L + E + +A L + R + +E + V+++V + +
Sbjct: 285 ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNV-HMLNRIRT 343
Query: 2204 SQQPKVDSALTEARQIRDDIADKDLVPKKQQAEAVFLNTTTQIERMNFFVQPVNEQAKAS 2263
Q+ A IRD + + + K A Q ++ N Q NE+A +
Sbjct: 344 WQKTHQGENNGLANSIRDSLNEYE--AKLSDLRARLQEAAAQAKQANGLNQE-NERALGA 400
Query: 2264 SHRPDLKFESLVNATRELKDKLDDMLEYTDLA 2295
R + SL + + D L T++A
Sbjct: 401 IQRQVKEINSLQSDFTKYLTTADSSLLQTNIA 432
Score = 98.7 bits (235), Expect = 3e-19
Identities = 55/164 (33%), Positives = 76/164 (46%), Gaps = 18/164 (10%)
Query: 1855 CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCA 1914
C+ GYY + L+TG C PCNC+G+ N C +G C+ C +NTAG C C
Sbjct: 59 CSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQ 110
Query: 1915 PGFYGDAIFSKNCTACICDEFG--MADCDSTTG--TCVCRPGVIGEKCDRCAPDHWG--L 1968
G+YG+A+ +C AC C C G C C+ G G +C+RCAP ++G
Sbjct: 111 EGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQ 169
Query: 1969 NTGLGCTPCNCGIASESTQCDDDNGQC---RCAKGVTGKQCDQC 2009
G C PC+C + C G C ++CD C
Sbjct: 170 KFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 94.7 bits (225), Expect = 6e-18
Identities = 56/168 (33%), Positives = 83/168 (49%), Gaps = 27/168 (16%)
Query: 384 EFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSC 436
EF+P C+ GY+ D+ C PC CN + + C G+C C++N AG+ C
Sbjct: 52 EFRPSQ--GCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHC 106
Query: 437 EICEDGYYSP----ECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQAGYYN 490
E C++GYY C+ C C S + C GD C+CK+ Y+G C +C GY+
Sbjct: 107 ERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG 166
Query: 491 YP-----TCKPCNCDTSGTEPSICDDVSGQCI---CKAGFGGPRCDQC 530
P +C+PC+C+++G S C ++G CI K CD C
Sbjct: 167 NPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 213
Score = 93.9 bits (223), Expect = 1e-17
Identities = 53/165 (32%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 479 RTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCL 531
R C GYY Y C PCNC+ + C D SG C+ C+ G C++C
Sbjct: 54 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHCERCQ 110
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQCSPGYYKYP 588
GYY + C C C T S +T C +G +C+C + G QC++C+PGY+ P
Sbjct: 111 EGYYGNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168
Query: 589 -----DCLSCNCDVSGSIGSTCDDNGLC---HCKSNFDGAKCDTC 625
C C+C+ +G +GS G C K + +CD C
Sbjct: 169 QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 89.8 bits (213), Expect = 2e-16
Identities = 57/164 (34%), Positives = 74/164 (45%), Gaps = 36/164 (21%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PCNC+ H+ +C +G G C+NCQHNT G +C +C+ Y
Sbjct: 75 CVPCNCNGHSNQCQ------------------DGSGICVNCQHNTAGEHCERCQEGY--- 113
Query: 348 YGKRWDELDVCQPCQCDPH---FSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP- 401
YG C+ C C PH F+TG C G RC C+ + C CA GYF P
Sbjct: 114 YGNAVH--GSCRACPC-PHTNSFATG-CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQ 169
Query: 402 ----NCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
+C+PC+CN NG G C P G C + E C+D
Sbjct: 170 KFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDD 212
Score = 85.8 bits (203), Expect = 3e-15
Identities = 52/160 (32%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 580 CSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFYNY 632
CSPGYY+ Y C+ CNC+ G D +G+C +C+ N G C+ C+E +Y
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 633 PACEECNCDPRGVTASFA-GCGSVPAGEL-CQCKDRVQGRICNDCKPLYWNLQEYNPFGC 690
C P T SFA GC V G++ C CK G C C P Y+ + C
Sbjct: 117 AVHGSCRACPCPHTNSFATGC-VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSC 175
Query: 691 EQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLD 730
+ C+CN G LG+C+ +G C+ ++ ++C D
Sbjct: 176 QPCSCNSNG---QLGSCHPLTGDCINQEPKDSSPAEECDD 212
Score = 74.9 bits (176), Expect = 5e-12
Identities = 47/171 (27%), Positives = 66/171 (38%), Gaps = 18/171 (10%)
Query: 1368 RTCSACRTGYY----GF--PNCRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYT 1418
R C GYY G C PC+C S D +G+C+ C N GE+C+RC+
Sbjct: 54 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGY 113
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP----- 1473
+ V C C C +C+C+ G C+ C PG++ P
Sbjct: 114 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 173
Query: 1474 DCYQCTCNRHGTTYDVCDQNTAQCY---CKTNVRGQACDTCKEEYFNLQDD 1521
C C+CN +G C T C K + + CD C L +D
Sbjct: 174 SCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLND 223
Score = 65.7 bits (153), Expect = 3e-09
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 36/169 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 78 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 124
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C P + +NG G +C +C+ G C +C P Y +G
Sbjct: 125 CPC----------PHTNSFATGCVVNG---GDVRC-SCKAGYTGTQCERCAPGY---FGN 167
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRC------ECRPEFQPPDCSSC 393
CQPC C+ + G+C +G C + P + DC SC
Sbjct: 168 PQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 216
Score = 61.3 bits (142), Expect = 6e-08
Identities = 34/111 (30%), Positives = 42/111 (37%), Gaps = 11/111 (9%)
Query: 1427 CDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCDHCVPGHYA---FPDCYQCTCNR 1482
C CNCN G+ QC+ SG C C+ N G C+ C G+Y C C C
Sbjct: 75 CVPCNCN-----GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPH 129
Query: 1483 HGTTYDVCDQN--TAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFC 1531
+ C N +C CK G C+ C YF C C C
Sbjct: 130 TNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
Score = 52.4 bits (120), Expect = 3e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCVPCQC--NGHSDQCDVNTGICLN--CADNT 1788
C C Y G CE+CA G++ P G C PC C NG C TG C+N D++
Sbjct: 146 CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 205
Query: 1789 IGDHCEFCMS 1798
+ C+ C S
Sbjct: 206 PAEECDDCDS 215
Score = 50.8 bits (116), Expect = 9e-05
Identities = 60/292 (20%), Positives = 118/292 (40%), Gaps = 30/292 (10%)
Query: 2725 RVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEK 2784
R+ + D +W+ V+ G + +L + D + ++E LPG+ TI +
Sbjct: 1391 RIKSKEKCNDGKWHTVVFGHDGEKGRLVV--------DGLRAREGSLPGNSTI----SIR 1438
Query: 2785 SKLYVGGVPSDAKLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQ 2844
+ +Y+G PS K + + +F G ++ + P+ + ++ + S
Sbjct: 1439 APVYLGSPPS-GKPKSLPTNSFVGCLKNFQLDSKPL----YTPSSSFG-------VSSCL 1486
Query: 2845 SGPQE---YRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
GP E Y + G+ +A L P+ V LI++ + G + ++
Sbjct: 1487 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1546
Query: 2902 DGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSA 2961
G+V + G V ++ DG+WH + L +D + P
Sbjct: 1547 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 1606
Query: 2962 DIPSLDTMNFGG--NNKGILQVPD-RGFDGCMRQISINGVNLDLSENLESIG 3010
+ + ++ GG N L++P + F GC+R I +N + + ++E LE G
Sbjct: 1607 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 1658
Score = 50.0 bits (114), Expect = 2e-04
Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 9/309 (2%)
Query: 2866 LTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
L P+S Q + +T + GL++ G F +L + GR L +LG + + +
Sbjct: 1341 LKPRS-QFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGR--LVFALGTDGKKLRIKSKEK 1397
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKG-ILQVPDR 2984
NDGKWH + K L VD + S ++ I + G G +P
Sbjct: 1398 CNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTN 1457
Query: 2985 GFDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTL 3044
F GC++ ++ L + + G + F+ ++ P+ L
Sbjct: 1458 SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKL 1517
Query: 3045 KFKTAKPNGL--LFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-TGLNTYNDSQW 3101
F + +P L + +++ + + V + + T + D QW
Sbjct: 1518 VF-SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQW 1576
Query: 3102 HVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFT 3161
H + VT L L +D ++ P P L +GG P + + + F
Sbjct: 1577 HSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGA-PANLTTLRIPVWKSFF 1635
Query: 3162 GCIGDATIN 3170
GC+ + +N
Sbjct: 1636 GCLRNIHVN 1644
Score = 48.4 bits (110), Expect = 5e-04
Identities = 31/131 (23%), Positives = 48/131 (36%), Gaps = 9/131 (6%)
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C CNC+ ++ GS G C+ G C C+ Y+ + C C
Sbjct: 75 CVPCNCNGH---SNQCQDGS---GICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACP 126
Query: 695 CNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSI 754
C + + N +C CK QC++C G++ C C C+ G +
Sbjct: 127 CPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL 186
Query: 755 DNNCDKTTGQC 765
+C TG C
Sbjct: 187 -GSCHPLTGDC 196
Score = 48.4 bits (110), Expect = 5e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 16/122 (13%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGG--QCPCKPN 1364
C + + + C+E + + + R C C S C GG +C CK
Sbjct: 94 CVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 151
Query: 1365 VIGRTCSACRTGYYGFP-----NCRPCHCPST---AICDD-NGMCIC--PKNVE-GENCD 1412
G C C GY+G P +C+PC C S C G CI PK+ E CD
Sbjct: 152 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECD 211
Query: 1413 RC 1414
C
Sbjct: 212 DC 213
Score = 45.6 bits (103), Expect = 0.003
Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 6/85 (7%)
Query: 1738 CPRAYRGLSCEQCAEGHY-RLPSGFCVPCQC---NGHSDQCDVNTG-ICLNCADNTIGDH 1792
C G CE+C EG+Y G C C C N + C VN G + +C G
Sbjct: 97 CQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQ 156
Query: 1793 CEFCMSGYHGDATVGTPRDCLICAC 1817
CE C GY G+ C C+C
Sbjct: 157 CERCAPGYFGNPQ-KFGGSCQPCSC 180
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 147 bits (355), Expect = 1e-33
Identities = 165/619 (26%), Positives = 226/619 (36%), Gaps = 97/619 (15%)
Query: 225 ISIGGRCMCNG---HADTCEPADPAGNLNI-LVCRCQHNTCGPQCNKCCSGFEQKKWRIS 280
++ C C G H T + P G C G C + C + R
Sbjct: 650 VNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA-RCD 708
Query: 281 QNWDRFSCEP----CNCHNHTTECTYDPEIDEKRLSLDINGR-YEGGGKCLNCQHNTEGI 335
C P C + Y P + R S +G + G C +C G
Sbjct: 709 PETGACLCLPGFVGSRCQDVCPAGWYGPSC-QTRCSCANDGHCHPATGHC-SCAPGWTGF 766
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CA 394
+C + T + W D PC C G+C+ SG C C + P C C
Sbjct: 767 SCQRACDTGH------WGP-DCSHPCNCSA--GHGSCDAISGLCLCEAGYVGPRCEQQCP 817
Query: 395 YGYFDYPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPECKN-C 451
G+F P C+ C C G C G C C + G CE C G++ +C++ C
Sbjct: 818 QGHFG-PGCEQLCQCQ----HGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC 872
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKPCNCDTSG--TEPSI 508
C T G+ CD + G C C + G C +C P C SG +
Sbjct: 873 NC-TAGAA---CDAVNGSCLCPAGRRGPRCAEKC------LPRDVRAGCRHSGGCLNGGL 922
Query: 509 CDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCN 567
CD +G+C+C AG+ G +C CL G++ + + C+C P + G C
Sbjct: 923 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR-----CSCPPAAACH---HVTGACR 974
Query: 568 CLTNFGGAQCDQ-CSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD- 623
C F G+ C+Q C PG Y P C C C GS CD G C C + F G C+
Sbjct: 975 CPPGFTGSGCEQGCPPGRYG-PGCEQLCGCLNGGS----CDAATGACRCPTGFLGTDCNL 1029
Query: 624 TCREQFYNYPACEECNC------DP----------RGVTASFAGCGSVPAGELCQ--CKD 665
TC + + C C DP R GC G C+ C
Sbjct: 1030 TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSC 1089
Query: 666 RVQGRICN----DCK-PLYWNLQEYN---PFGCEQCNCNLAGTLNSLGACNTKSGQCVCK 717
R G +C+ C L W + P G C+L + ++ C +G C C
Sbjct: 1090 R-NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1148
Query: 718 QHVGERQCDQCLDGFY-RLQTN-DVFG--CTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
+ C+ G L FG CT CD GG D CD +GQCHC G
Sbjct: 1149 PGFYGQACEHRRSGATCNLDCRRGQFGPSCT-LHCDCGGGAD--CDPVSGQCHCVDGYMG 1205
Query: 774 RRCDQ--PIRAHYFPTLHQ 790
C + P+R P+L Q
Sbjct: 1206 PTCREGGPLRLPENPSLAQ 1224
Score = 145 bits (352), Expect = 2e-33
Identities = 138/485 (28%), Positives = 185/485 (38%), Gaps = 83/485 (17%)
Query: 322 GGKCL------NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEE 374
GG CL +C G+ CN+ P +GK C C C + G C+
Sbjct: 442 GGTCLLGLDGCDCPEGWTGLICNETCPP--DTFGKN------CSFSCSCQ---NGGTCDS 490
Query: 375 ESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
+G C C P +C C GY+ K C C G C G C C G
Sbjct: 491 VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRG----RCHRLYGACLCDPGLYG 546
Query: 434 KSCEI-CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNY 491
+ C + C + P C EC V + CDK G C+CK+ + G C +C+ GY+
Sbjct: 547 RFCHLTCPPWAFGPGCSE-ECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGP 605
Query: 492 PTCKPCNCDTSGTEPSICDDVSGQC--ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPC 548
+ C C CD VSG+C C AGF G C Q C G + C
Sbjct: 606 GCWQACTCPVG----VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGA 661
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPDCLSCN--CDVSGSIGSTC 605
C G T G+C C G C+ C G + L C C
Sbjct: 662 PCH--GVT-------GQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHAARCD 708
Query: 606 DDNGLCHCKSNFDGAKC-DTCREQFYNYPACE-ECNCDPRGVTASFAGCGSVPAGELCQC 663
+ G C C F G++C D C +Y P+C+ C+C A+ C PA C C
Sbjct: 709 PETGACLCLPGFVGSRCQDVCPAGWYG-PSCQTRCSC------ANDGHCH--PATGHCSC 759
Query: 664 KDRVQGRIC-NDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG 721
G C C +W P CNC+ AG G+C+ SG C+C+ +VG
Sbjct: 760 APGWTGFSCQRACDTGHW-----GPDCSHPCNCS-AGH----GSCDAISGLCLCEAGYVG 809
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
R QC G + GC + C C G + CD +G C C + G C+
Sbjct: 810 PRCEQQCPQGHFGP------GCEQLCQCQHGAA----CDHVSGACTCPAGWRGTFCEHAC 859
Query: 781 RAHYF 785
A +F
Sbjct: 860 PAGFF 864
Score = 126 bits (305), Expect = 1e-27
Identities = 107/326 (32%), Positives = 134/326 (41%), Gaps = 62/326 (19%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C CP RG C E+C R C G CD +TG CL C GD C+
Sbjct: 887 CLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGG---LCDPHTGRCL-CPAGWTGDKCQ 942
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C+ G+ G+A C+CP A +C +C C PG+ G+ CE
Sbjct: 943 SPCLRGWFGEACAQR------CSCPP-------AAACHHVTG----ACRCPPGFTGSGCE 985
Query: 1854 Y-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
C G YG P L C C GSCD+ G C +C G CNL
Sbjct: 986 QGCPPGRYG-PGCEQL--------CGCLNG------GSCDAATGAC-RCPTGFLGTDCNL 1029
Query: 1913 CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
P F NCT C C + G A CD TGTC+C PG G +C+R P + G
Sbjct: 1030 TCP----QGRFGPNCTHVCGCGQ-GAA-CDPVTGTCLCPPGRAGVRCERGCPQN---RFG 1080
Query: 1972 LGCT-PCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCDHCNCNTG 2029
+GC C+C C NG C C G TG+ C+ C G Y C+C+
Sbjct: 1081 VGCEHTCSC---RNGGLCHASNGSCSCGLGWTGRHCELACPPG--RYGAACHLECSCHNN 1135
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCD 2054
+ C ATG C C PG G+ C+
Sbjct: 1136 ST----CEPATGTCRCGPGFYGQACE 1157
Score = 122 bits (294), Expect = 2e-26
Identities = 110/352 (31%), Positives = 148/352 (42%), Gaps = 66/352 (18%)
Query: 1735 ECQCPRAYRGLSCE-QCAEGHYRLP-SGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDH 1792
+C+CP G CE C EG + L C CQ H+ +CD TG CL C +G
Sbjct: 669 QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQ---HAARCDPETGACL-CLPGFVGSR 724
Query: 1793 CE-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGAR 1851
C+ C +G++G P C+C +N+ C + C+C PG+ G
Sbjct: 725 CQDVCPAGWYG------PSCQTRCSC-----ANDG--HCHPATG----HCSCAPGWTGFS 767
Query: 1852 CEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C+ C G++G D PCNCS GSCD+I+G CL C G C
Sbjct: 768 CQRACDTGHWG---------PDCSHPCNCSAG-----HGSCDAISGLCL-CEAGYVGPRC 812
Query: 1911 NL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C G +G C C + G A CD +G C C G G C+ P +
Sbjct: 813 EQQCPQGHFGPGCEQ----LCQC-QHGAA-CDHVSGACTCPAGWRGTFCEHACPAGF--- 863
Query: 1970 TGLGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCN 2027
GL C + CNC + CD NG C C G G +C ++C + GC H +
Sbjct: 864 FGLDCRSACNC---TAGAACDAVNGSCLCPAGRRGPRCAEKCLP---RDVRAGCRH---S 914
Query: 2028 TGYSVGFMCNA-TGQCECLPGVIGEKCDR-CPERWVLIPQEGCLECDSCTDA 2077
G G +C+ TG+C C G G+KC C W E C + SC A
Sbjct: 915 GGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWF---GEACAQRCSCPPA 963
Score = 114 bits (274), Expect = 7e-24
Identities = 108/364 (29%), Positives = 140/364 (38%), Gaps = 56/364 (15%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C + G SC++ C GH+ PC C+ CD +G+CL C +G CE
Sbjct: 757 CSCAPGWTGFSCQRACDTGHWGPDCSH--PCNCSAGHGSCDAISGLCL-CEAGYVGPRCE 813
Query: 1795 F-CMSGYHGDATV-------GTPRDCL--ICACPMPYPSNNFALSCDLSENG--SLISCN 1842
C G+ G G D + C CP + +C G +CN
Sbjct: 814 QQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACN 873
Query: 1843 CQPGYGGARCE------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C GA C+ C AG G D C SG + G CD G
Sbjct: 874 CT---AGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGC--LNGGLCDPHTG 928
Query: 1897 DCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG 1955
CL C G C C G++G+A + C C A C TG C C PG G
Sbjct: 929 RCL-CPAGWTGDKCQSPCLRGWFGEACAQR----CSCPP--AAACHHVTGACRCPPGFTG 981
Query: 1956 EKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C++ C P +G GC CG + + CD G CRC G G C+ C G
Sbjct: 982 SGCEQGCPPGRYGP----GCEQL-CGCLNGGS-CDAATGACRCPTGFLGTDCNLTCPQGR 1035
Query: 2014 WNYTKDGCDH-CNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDR-CPERWVLIPQEGCLE 2070
+ C H C C G + C+ TG C C PG G +C+R CP+ + GC
Sbjct: 1036 FG---PNCTHVCGCGQGAA----CDPVTGTCLCPPGRAGVRCERGCPQNRFGV---GCEH 1085
Query: 2071 CDSC 2074
SC
Sbjct: 1086 TCSC 1089
Score = 113 bits (273), Expect = 9e-24
Identities = 96/332 (28%), Positives = 130/332 (39%), Gaps = 60/332 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C G C + G CQC H+ CD G C +C G+ C+
Sbjct: 538 CLCDPGLYGRFCHLTCPP-WAFGPGCSEECQCVQPHTQSCDKRDGSC-SCKAGFRGERCQ 595
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC- 1852
C GY G P C CP+ ++CD S +G C G+ G C
Sbjct: 596 AECELGYFG------PGCWQACTCPV-------GVACD-SVSGEC-GKRCPAGFQGEDCG 640
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ C G +G+ + C+C G C + G C +C G C
Sbjct: 641 QECPVGTFGV---------NCSSSCSCGG-------APCHGVTGQC-RCPPGRTGEDCEA 683
Query: 1913 -CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
C G +G + C AC A CD TG C+C PG +G +C P W G
Sbjct: 684 DCPEGRWGLGC-QEICPACQ----HAARCDPETGACLCLPGFVGSRCQDVCPAGW---YG 735
Query: 1972 LGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDH-CNCNT 2028
C T C+C + C G C CA G TG C + C G W C H CNC+
Sbjct: 736 PSCQTRCSC---ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG---PDCSHPCNCSA 789
Query: 2029 GYSVGFMCNA-TGQCECLPGVIGEKCD-RCPE 2058
G+ C+A +G C C G +G +C+ +CP+
Sbjct: 790 GHG---SCDAISGLCLCEAGYVGPRCEQQCPQ 818
Score = 113 bits (271), Expect = 2e-23
Identities = 107/350 (30%), Positives = 130/350 (37%), Gaps = 55/350 (15%)
Query: 1733 VEECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
++ C CP + GL C E C + F CQ G CD TG C C G
Sbjct: 449 LDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG---TCDSVTGAC-RCPPGVSGT 504
Query: 1792 HCE-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
+CE C GY+G R CA A CD G C P G
Sbjct: 505 NCEDGCPKGYYGKHC----RKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP 560
Query: 1851 RCEYCAAGYYGIPEDTDLHTGD-YCKP------CNCSGNINPQDPG-----------SCD 1892
C + D G CK C + PG +CD
Sbjct: 561 GCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACD 620
Query: 1893 SINGDCLK-CVNNTAGAACNL-CAPGFYGDAIFSKNC-TACICDEFGMADCDSTTGTCVC 1949
S++G+C K C G C C G +G NC ++C C G A C TG C C
Sbjct: 621 SVSGECGKRCPAGFQGEDCGQECPVGTFG-----VNCSSSCSC---GGAPCHGVTGQCRC 672
Query: 1950 RPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC-D 2007
PG GE C+ C W GLGC C + +CD + G C C G G +C D
Sbjct: 673 PPGRTGEDCEADCPEGRW----GLGCQEI-CPACQHAARCDPETGACLCLPGFVGSRCQD 727
Query: 2008 QCAAGFWNYTKDGCDHCNC-NTGYSVGFMCN-ATGQCECLPGVIGEKCDR 2055
C AG W Y C+C N G+ C+ ATG C C PG G C R
Sbjct: 728 VCPAG-W-YGPSCQTRCSCANDGH-----CHPATGHCSCAPGWTGFSCQR 770
Score = 97.5 bits (232), Expect = 8e-19
Identities = 97/355 (27%), Positives = 130/355 (36%), Gaps = 49/355 (13%)
Query: 438 ICEDGYYSPECK-NCE-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTC 494
+C D + +C C+ C G+ D C C ++G CN+ C +
Sbjct: 422 VCLDDSFGHDCSLTCDDCRNGGTCLLGLD----GCDCPEGWTGLICNETCPPDTFGKNCS 477
Query: 495 KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPT 553
C+C GT CD V+G C C G G C D C GYY + ++ CNC
Sbjct: 478 FSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKK-----CNCANR 528
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCH 612
G G C C G C P + P C S C +CD +G C
Sbjct: 529 GRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGC-SEECQCVQPHTQSCDKRDGSCS 584
Query: 613 CKSNFDGAKCDTCREQFYNYPAC-EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
CK+ F G +C E Y P C + C C P GV C SV +C QG
Sbjct: 585 CKAGFRGERCQAECELGYFGPGCWQACTC-PVGV-----ACDSVSGECGKRCPAGFQGED 638
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD-QCLD 730
C QE P G NC+ + + C+ +GQC C C+ C +
Sbjct: 639 CG---------QEC-PVGTFGVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCEADCPE 687
Query: 731 GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
G + L ++ C C CD TG C C G RC A ++
Sbjct: 688 GRWGLGCQEI--CPACQHAA------RCDPETGACLCLPGFVGSRCQDVCPAGWY 734
Score = 96.7 bits (230), Expect = 1e-18
Identities = 76/240 (31%), Positives = 108/240 (45%), Gaps = 37/240 (15%)
Query: 1827 ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
+L+CD NG C G G C+ C G+ G+ + + K NCS + + Q
Sbjct: 433 SLTCDDCRNGG----TCLLGLDG--CD-CPEGWTGLICNETCPPDTFGK--NCSFSCSCQ 483
Query: 1887 DPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNC-TACICDEFGMADCDSTT 1944
+ G+CDS+ G C +C +G C + C G+YG K+C C C G C
Sbjct: 484 NGGTCDSVTGAC-RCPPGVSGTNCEDGCPKGYYG-----KHCRKKCNCANRGR--CHRLY 535
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKGVTG 2003
G C+C PG+ G C P W G GC+ C C + + CD +G C C G G
Sbjct: 536 GACLCDPGLYGRFCHLTCPP-WAF--GPGCSEECQC-VQPHTQSCDKRDGSCSCKAGFRG 591
Query: 2004 KQCD-QCAAGFWNYTKDGC-DHCNCNTGYSVGFMCNA-TGQC--ECLPGVIGEKC-DRCP 2057
++C +C G++ GC C C VG C++ +G+C C G GE C CP
Sbjct: 592 ERCQAECELGYFG---PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECP 644
Score = 89.4 bits (212), Expect = 2e-16
Identities = 55/163 (33%), Positives = 73/163 (44%), Gaps = 19/163 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAICDD-NGMCICPKNVEG 1408
C+ G C C +G C+ C G +G PNC C C A CD G C+CP G
Sbjct: 1009 CDAATGACRCPTGFLGTDCNLTCPQGRFG-PNCTHVCGCGQGAACDPVTGTCLCPPGRAG 1067
Query: 1409 ENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HCV 1466
C+R P F V GC+ C+C G+ C A +G C+C GR C+ C
Sbjct: 1068 VRCERGCPQN-RFGV--GCEHTCSCRNGGL------CHASNGSCSCGLGWTGRHCELACP 1118
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
PG Y +C+C+ + T C+ T C C GQAC+
Sbjct: 1119 PGRYGAACHLECSCHNNST----CEPATGTCRCGPGFYGQACE 1157
Score = 86.6 bits (205), Expect = 1e-15
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C++ G C C P V G C C GYYG +CR C+C + C G C+C + G
Sbjct: 488 CDSVTGACRCPPGVSGTNCEDGCPKGYYG-KHCRKKCNCANRGRCHRLYGACLCDPGLYG 546
Query: 1409 ENCD-RCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HC 1465
C C P+ F GC ++C C V + C+ G C+C+ RG C C
Sbjct: 547 RFCHLTCPPWAFG----PGCSEECQC----VQPHTQSCDKRDGSCSCKAGFRGERCQAEC 598
Query: 1466 VPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQC--YCKTNVRGQAC-DTCKEEYFNLQDD 1521
G++ P C+Q CTC CD + +C C +G+ C C F +
Sbjct: 599 ELGYFG-PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCS 653
Query: 1522 NPDGCTKCFCFGKTTRC 1538
+ C C G T +C
Sbjct: 654 SSCSCGGAPCHGVTGQC 670
Score = 81.8 bits (193), Expect = 4e-14
Identities = 59/194 (30%), Positives = 80/194 (41%), Gaps = 20/194 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPST-AICDD-NGMCICPKNVE 1407
C+ G C C P G +C AC TG++G P+C PC+C + CD +G+C+C
Sbjct: 750 CHPATGHCSCAPGWTGFSCQRACDTGHWG-PDCSHPCNCSAGHGSCDAISGLCLCEAGYV 808
Query: 1408 GENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCV 1466
G C++ P +F GC+ C C + C+ SG C C RG C+H
Sbjct: 809 GPRCEQQCPQG-HFGP--GCEQLCQCQ------HGAACDHVSGACTCPAGWRGTFCEHAC 859
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYFNLQDDNPDG 1525
P + DC + CN T CD C C RG C + C + G
Sbjct: 860 PAGFFGLDC-RSACN--CTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGG 916
Query: 1526 CTK-CFCFGKTTRC 1538
C C T RC
Sbjct: 917 CLNGGLCDPHTGRC 930
Score = 81.8 bits (193), Expect = 4e-14
Identities = 80/260 (30%), Positives = 97/260 (37%), Gaps = 51/260 (19%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGIC------------ 1781
C+CP + G CEQ C G Y G C C NG S CD TG C
Sbjct: 973 CRCPPGFTGSGCEQGCPPGRYG--PGCEQLCGCLNGGS--CDAATGACRCPTGFLGTDCN 1028
Query: 1782 LNCADNTIGDHCEF---CMSGYHGDATVGT---PRDCLICACPMPYPSNNFALSCDLS-- 1833
L C G +C C G D GT P C P N F + C+ +
Sbjct: 1029 LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1088
Query: 1834 -ENGSLI-----SCNCQPGYGGARCEY-CAAGYYGIP--EDTDLHTGDYCKPCNCSGNIN 1884
NG L SC+C G+ G CE C G YG + H C+P +
Sbjct: 1089 CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1148
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDST 1943
P G C + +GA CNL C G +G + CT CD G ADCD
Sbjct: 1149 PGFYGQA---------CEHRRSGATCNLDCRRGQFGPS-----CTLH-CDCGGGADCDPV 1193
Query: 1944 TGTCVCRPGVIGEKCDRCAP 1963
+G C C G +G C P
Sbjct: 1194 SGQCHCVDGYMGPTCREGGP 1213
Score = 74.5 bits (175), Expect = 6e-12
Identities = 53/195 (27%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G+C C G C S C G++G + C CP A C G C CP G
Sbjct: 923 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGS 982
Query: 1410 NCDR-CKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C++ C P + GC+ C C N C+A +G C C G C+ P
Sbjct: 983 GCEQGCPPGRYG----PGCEQLCGCL------NGGSCDAATGACRCPTGFLGTDCNLTCP 1032
Query: 1468 GHYAFPDC-YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT-CKEEYFNLQDDNPDG 1525
P+C + C C + CD T C C G C+ C + F + ++
Sbjct: 1033 QGRFGPNCTHVCGCGQGA----ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1088
Query: 1526 CTK-CFCFGKTTRCS 1539
C C CS
Sbjct: 1089 CRNGGLCHASNGSCS 1103
Score = 73.7 bits (173), Expect = 1e-11
Identities = 53/186 (28%), Positives = 73/186 (39%), Gaps = 23/186 (12%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRP-CHCPSTAIC 1394
+ PC C + C+ G C C+ +G C C G++G P C C C A C
Sbjct: 782 SHPCNCS---AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG-PGCEQLCQCQHGAAC 837
Query: 1395 DD-NGMCICPKNVEGENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
D +G C CP G C+ C F D + C NC G C+A +G C
Sbjct: 838 DHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC---NCTA-GAA-----CDAVNGSCL 888
Query: 1453 CRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT- 1510
C RG C + C+P + C G +CD +T +C C G C +
Sbjct: 889 CPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGG----LCDPHTGRCLCPAGWTGDKCQSP 944
Query: 1511 CKEEYF 1516
C +F
Sbjct: 945 CLRGWF 950
Score = 72.9 bits (171), Expect = 2e-11
Identities = 57/190 (30%), Positives = 77/190 (40%), Gaps = 23/190 (12%)
Query: 1889 GSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGT 1946
G+C + D C G CN C P +G KNC+ +C C G CDS TG
Sbjct: 443 GTC-LLGLDGCDCPEGWTGLICNETCPPDTFG-----KNCSFSCSCQNGGT--CDSVTGA 494
Query: 1947 CVCRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQ 2005
C C PGV G C D C ++G + CNC + +C G C C G+ G+
Sbjct: 495 CRCPPGVSGTNCEDGCPKGYYGKHCR---KKCNC---ANRGRCHRLYGACLCDPGLYGRF 548
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP 2064
C W + + C C ++ C+ G C C G GE+C E P
Sbjct: 549 C-HLTCPPWAFGPGCSEECQCVQPHTQS--CDKRDGSCSCKAGFRGERCQAECELGYFGP 605
Query: 2065 QEGCLECDSC 2074
GC + +C
Sbjct: 606 --GCWQACTC 613
Score = 62.9 bits (146), Expect = 2e-08
Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 18/182 (9%)
Query: 1352 CNTFGGQCP--CKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEG 1408
C++ G+C C G C C G +G C C G C CP G
Sbjct: 619 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 678
Query: 1409 ENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
E+C+ C + Q C C + +C+ ++G C C G C P
Sbjct: 679 EDCEADCPEGRWGLGCQEICPACQ--------HAARCDPETGACLCLPGFVGSRCQDVCP 730
Query: 1468 GHYAFPDCY-QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNPDG 1525
+ P C +C+C G C T C C G +C C ++ +P
Sbjct: 731 AGWYGPSCQTRCSCANDGH----CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 786
Query: 1526 CT 1527
C+
Sbjct: 787 CS 788
Score = 62.9 bits (146), Expect = 2e-08
Identities = 46/168 (27%), Positives = 63/168 (37%), Gaps = 22/168 (13%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
C+ G C C P G C C +G C C + +C NG C C G
Sbjct: 1052 CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGR 1111
Query: 1410 NCD-RCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
+C+ C P + C +C+C+ N CE +G C C G+ C+H
Sbjct: 1112 HCELACPPGRYG----AACHLECSCH------NNSTCEPATGTCRCGPGFYGQACEHRRS 1161
Query: 1468 GHYAFPDC----YQCTCNRH---GTTYDVCDQNTAQCYCKTNVRGQAC 1508
G DC + +C H G D CD + QC+C G C
Sbjct: 1162 GATCNLDCRRGQFGPSCTLHCDCGGGAD-CDPVSGQCHCVDGYMGPTC 1208
Score = 50.4 bits (115), Expect = 1e-04
Identities = 62/240 (25%), Positives = 80/240 (33%), Gaps = 36/240 (15%)
Query: 1869 HTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNLCAPGFYGDAIFSKNC 1927
H G P + +G+ P D C + NG C +CVN C C PGF S+ C
Sbjct: 57 HLGQAGYPVS-AGDQRP-DVDECRTHNGGCQHRCVNTPGSYLCE-CKPGFRLHT-DSRTC 112
Query: 1928 TACICDEFGMADCDS-------TTGTCVCRPGV-IGEKCDRCAPDHWGLNTGLGCTPCNC 1979
A G C T C CRPG + E C N C C
Sbjct: 113 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RC 171
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN-----YTKDGCDHCNCNTGYSVGF 2034
+ +C+ G A G + D+CAAG G C C+ GY +G
Sbjct: 172 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGA 231
Query: 2035 ---MC-----NATGQCECLPGVIGEKCDR--------CPERWVL-IPQEGCLECDSCTDA 2077
C CE G C CP + L Q C++ D C D+
Sbjct: 232 DGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS 291
Score = 48.8 bits (111), Expect = 4e-04
Identities = 87/343 (25%), Positives = 119/343 (34%), Gaps = 67/343 (19%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQH---NTEGINCNKCRPTY 344
C PC H + Y ++R +D + GG CQH NT G +C+P +
Sbjct: 53 CYPC----HLGQAGYPVSAGDQRPDVDECRTHNGG-----CQHRCVNTPGSYLCECKPGF 103
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTGNCEEES---GRCECRPEFQ-PPDCSSCAYGYFDY 400
R C +C + + RC+CRP FQ D C
Sbjct: 104 RLHTDSR--TCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV------ 155
Query: 401 PNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYA----GKSCE-ICEDGYYSPECKNCEC 453
PC N NG+ C GL C C Y GK+CE + E +C +
Sbjct: 156 -RRSPC-ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCL 213
Query: 454 NTVGSVSYVCD---KLTGDCTCKSKYSGRTCNQCQAGY------YNYPTCKP-CNCDTS- 502
NT GS VC +L D + N C+A ++ + P C C
Sbjct: 214 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 273
Query: 503 --GTEPSICDDVSG-------QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
T+ C DV Q +C GG C C +GY + G C C+
Sbjct: 274 ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECG-CYAGYRLSADG-------CGCE-- 323
Query: 554 GSTSTSCSADGKC--NCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
S+ G C +C G QC C GY + D C+
Sbjct: 324 -DVDECASSRGGCEHHCTNLAGSFQC-SCEAGYRLHEDRRGCS 364
Score = 48.8 bits (111), Expect = 4e-04
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 19/133 (14%)
Query: 1383 CRPCHCPSTAICDDNGMCICPKNVEGENCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGN 1440
C C T + +G C CP+ G C+ C P TF + C C+C G
Sbjct: 436 CDDCRNGGTCLLGLDG-CDCPEGWTGLICNETCPPDTFG----KNCSFSCSCQNGGT--- 487
Query: 1441 QLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
C++ +G C C V G C D C G+Y +C C G C + C C
Sbjct: 488 ---CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR----CHRLYGACLC 540
Query: 1500 KTNVRGQACD-TC 1511
+ G+ C TC
Sbjct: 541 DPGLYGRFCHLTC 553
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 146 bits (353), Expect = 2e-33
Identities = 165/619 (26%), Positives = 226/619 (36%), Gaps = 97/619 (15%)
Query: 225 ISIGGRCMCNG---HADTCEPADPAGNLNI-LVCRCQHNTCGPQCNKCCSGFEQKKWRIS 280
++ C C G H T + P G C G C + C + R
Sbjct: 633 VNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA-RCD 691
Query: 281 QNWDRFSCEP----CNCHNHTTECTYDPEIDEKRLSLDINGR-YEGGGKCLNCQHNTEGI 335
C P C + Y P + R S +G + G C +C G
Sbjct: 692 PETGACLCLPGFVGSRCQDVCPAGWYGPSC-QTRCSCANDGHCHPATGHC-SCAPGWTGF 749
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CA 394
+C + T + W D PC C G+C+ SG C C + P C C
Sbjct: 750 SCQRACDTGH------WGP-DCSHPCNCSA--GHGSCDAISGLCLCEAGYVGPRCEQQCP 800
Query: 395 YGYFDYPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPECKN-C 451
G+F P C+ C C G C G C C + G CE C G++ +C++ C
Sbjct: 801 QGHFG-PGCEQRCQCQ----HGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC 855
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKPCNCDTSG--TEPSI 508
C T G+ CD + G C C + G C +C P C SG +
Sbjct: 856 NC-TAGAA---CDAVNGSCLCPAGRRGPRCAEKC------LPRDVRAGCRHSGGCLNGGL 905
Query: 509 CDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCN 567
CD +G+C+C AG+ G +C CL G++ + + C+C P + G C
Sbjct: 906 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR-----CSCPPGAACH---HVTGACR 957
Query: 568 CLTNFGGAQCDQ-CSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD- 623
C F G+ C+Q C PG Y P C C C GS CD G C C + F G C+
Sbjct: 958 CPPGFTGSGCEQGCPPGRYG-PGCEQLCGCLNGGS----CDAATGACRCPTGFLGTDCNL 1012
Query: 624 TCREQFYNYPACEECNC------DP----------RGVTASFAGCGSVPAGELCQ--CKD 665
TC + + C C DP R GC G C+ C
Sbjct: 1013 TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSC 1072
Query: 666 RVQGRICN----DCK-PLYWNLQEYN---PFGCEQCNCNLAGTLNSLGACNTKSGQCVCK 717
R G +C+ C L W + P G C+L + ++ C +G C C
Sbjct: 1073 R-NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1131
Query: 718 QHVGERQCDQCLDGFY-RLQTN-DVFG--CTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
+ C+ G L FG CT CD GG D CD +GQCHC G
Sbjct: 1132 PGFYGQACEHRRSGATCNLDCRRGQFGPSCT-LHCDCGGGAD--CDPVSGQCHCVDGYMG 1188
Query: 774 RRCDQ--PIRAHYFPTLHQ 790
C + P+R P+L Q
Sbjct: 1189 PTCREGGPLRLPENPSLAQ 1207
Score = 145 bits (352), Expect = 2e-33
Identities = 138/485 (28%), Positives = 185/485 (38%), Gaps = 83/485 (17%)
Query: 322 GGKCL------NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEE 374
GG CL +C G+ CN+ P +GK C C C + G C+
Sbjct: 425 GGTCLLGLDGCDCPEGWTGLICNETCPP--DTFGKN------CSFSCSCQ---NGGTCDS 473
Query: 375 ESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
+G C C P +C C GY+ K C C G C G C C G
Sbjct: 474 VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRG----RCHRLYGACLCDPGLYG 529
Query: 434 KSCEI-CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNY 491
+ C + C + P C EC V + CDK G C+CK+ + G C +C+ GY+
Sbjct: 530 RFCHLTCPPWAFGPGCSE-ECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGP 588
Query: 492 PTCKPCNCDTSGTEPSICDDVSGQC--ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPC 548
+ C C CD VSG+C C AGF G C Q C G + C
Sbjct: 589 GCWQACTCPVG----VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGA 644
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPDCLSCN--CDVSGSIGSTC 605
C G T G+C C G C+ C G + L C C
Sbjct: 645 PCH--GVT-------GQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHAARCD 691
Query: 606 DDNGLCHCKSNFDGAKC-DTCREQFYNYPACE-ECNCDPRGVTASFAGCGSVPAGELCQC 663
+ G C C F G++C D C +Y P+C+ C+C A+ C PA C C
Sbjct: 692 PETGACLCLPGFVGSRCQDVCPAGWYG-PSCQTRCSC------ANDGHCH--PATGHCSC 742
Query: 664 KDRVQGRIC-NDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG 721
G C C +W P CNC+ AG G+C+ SG C+C+ +VG
Sbjct: 743 APGWTGFSCQRACDTGHW-----GPDCSHPCNCS-AGH----GSCDAISGLCLCEAGYVG 792
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
R QC G + GC + C C G + CD +G C C + G C+
Sbjct: 793 PRCEQQCPQGHFGP------GCEQRCQCQHGAA----CDHVSGACTCPAGWRGTFCEHAC 842
Query: 781 RAHYF 785
A +F
Sbjct: 843 PAGFF 847
Score = 125 bits (301), Expect = 3e-27
Identities = 106/326 (32%), Positives = 133/326 (40%), Gaps = 62/326 (19%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C CP RG C E+C R C G CD +TG CL C GD C+
Sbjct: 870 CLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGG---LCDPHTGRCL-CPAGWTGDKCQ 925
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C+ G+ G+A C+CP +C +C C PG+ G+ CE
Sbjct: 926 SPCLRGWFGEACAQR------CSCPP-------GAACHHVTG----ACRCPPGFTGSGCE 968
Query: 1854 Y-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
C G YG P L C C GSCD+ G C +C G CNL
Sbjct: 969 QGCPPGRYG-PGCEQL--------CGCLNG------GSCDAATGAC-RCPTGFLGTDCNL 1012
Query: 1913 CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
P F NCT C C + G A CD TGTC+C PG G +C+R P + G
Sbjct: 1013 TCP----QGRFGPNCTHVCGCGQ-GAA-CDPVTGTCLCPPGRAGVRCERGCPQN---RFG 1063
Query: 1972 LGCT-PCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCDHCNCNTG 2029
+GC C+C C NG C C G TG+ C+ C G Y C+C+
Sbjct: 1064 VGCEHTCSC---RNGGLCHASNGSCSCGLGWTGRHCELACPPG--RYGAACHLECSCHNN 1118
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCD 2054
+ C ATG C C PG G+ C+
Sbjct: 1119 ST----CEPATGTCRCGPGFYGQACE 1140
Score = 113 bits (273), Expect = 9e-24
Identities = 96/332 (28%), Positives = 130/332 (39%), Gaps = 60/332 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C G C + G CQC H+ CD G C +C G+ C+
Sbjct: 521 CLCDPGLYGRFCHLTCPP-WAFGPGCSEECQCVQPHTQSCDKRDGSC-SCKAGFRGERCQ 578
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC- 1852
C GY G P C CP+ ++CD S +G C G+ G C
Sbjct: 579 AECELGYFG------PGCWQACTCPV-------GVACD-SVSGEC-GKRCPAGFQGEDCG 623
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ C G +G+ + C+C G C + G C +C G C
Sbjct: 624 QECPVGTFGV---------NCSSSCSCGG-------APCHGVTGQC-RCPPGRTGEDCEA 666
Query: 1913 -CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
C G +G + C AC A CD TG C+C PG +G +C P W G
Sbjct: 667 DCPEGRWGLGC-QEICPACQ----HAARCDPETGACLCLPGFVGSRCQDVCPAGW---YG 718
Query: 1972 LGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDH-CNCNT 2028
C T C+C + C G C CA G TG C + C G W C H CNC+
Sbjct: 719 PSCQTRCSC---ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG---PDCSHPCNCSA 772
Query: 2029 GYSVGFMCNA-TGQCECLPGVIGEKCD-RCPE 2058
G+ C+A +G C C G +G +C+ +CP+
Sbjct: 773 GHG---SCDAISGLCLCEAGYVGPRCEQQCPQ 801
Score = 113 bits (273), Expect = 9e-24
Identities = 109/364 (29%), Positives = 141/364 (38%), Gaps = 56/364 (15%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C + G SC++ C GH+ PC C+ CD +G+CL C +G CE
Sbjct: 740 CSCAPGWTGFSCQRACDTGHWGPDCSH--PCNCSAGHGSCDAISGLCL-CEAGYVGPRCE 796
Query: 1795 F-CMSGYHGDATV-------GTPRDCL--ICACPMPYPSNNFALSCDLSENG--SLISCN 1842
C G+ G G D + C CP + +C G +CN
Sbjct: 797 QQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACN 856
Query: 1843 CQPGYGGARCE------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C GA C+ C AG G D C SG + G CD G
Sbjct: 857 CT---AGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGC--LNGGLCDPHTG 911
Query: 1897 DCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG 1955
CL C G C C G++G+A + C C G A C TG C C PG G
Sbjct: 912 RCL-CPAGWTGDKCQSPCLRGWFGEACAQR----CSCPP-GAA-CHHVTGACRCPPGFTG 964
Query: 1956 EKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C++ C P + G GC CG + + CD G CRC G G C+ C G
Sbjct: 965 SGCEQGCPPGRY----GPGCEQL-CGCLNGGS-CDAATGACRCPTGFLGTDCNLTCPQGR 1018
Query: 2014 WNYTKDGCDH-CNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDR-CPERWVLIPQEGCLE 2070
+ C H C C G + C+ TG C C PG G +C+R CP+ + GC
Sbjct: 1019 FG---PNCTHVCGCGQGAA----CDPVTGTCLCPPGRAGVRCERGCPQNRFGV---GCEH 1068
Query: 2071 CDSC 2074
SC
Sbjct: 1069 TCSC 1072
Score = 113 bits (271), Expect = 2e-23
Identities = 107/350 (30%), Positives = 130/350 (37%), Gaps = 55/350 (15%)
Query: 1733 VEECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
++ C CP + GL C E C + F CQ G CD TG C C G
Sbjct: 432 LDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG---TCDSVTGAC-RCPPGVSGT 487
Query: 1792 HCE-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
+CE C GY+G R CA A CD G C P G
Sbjct: 488 NCEDGCPKGYYGKHC----RKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP 543
Query: 1851 RCEYCAAGYYGIPEDTDLHTGD-YCKP------CNCSGNINPQDPG-----------SCD 1892
C + D G CK C + PG +CD
Sbjct: 544 GCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACD 603
Query: 1893 SINGDCLK-CVNNTAGAACNL-CAPGFYGDAIFSKNC-TACICDEFGMADCDSTTGTCVC 1949
S++G+C K C G C C G +G NC ++C C G A C TG C C
Sbjct: 604 SVSGECGKRCPAGFQGEDCGQECPVGTFG-----VNCSSSCSC---GGAPCHGVTGQCRC 655
Query: 1950 RPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC-D 2007
PG GE C+ C W GLGC C + +CD + G C C G G +C D
Sbjct: 656 PPGRTGEDCEADCPEGRW----GLGCQEI-CPACQHAARCDPETGACLCLPGFVGSRCQD 710
Query: 2008 QCAAGFWNYTKDGCDHCNC-NTGYSVGFMCN-ATGQCECLPGVIGEKCDR 2055
C AG W Y C+C N G+ C+ ATG C C PG G C R
Sbjct: 711 VCPAG-W-YGPSCQTRCSCANDGH-----CHPATGHCSCAPGWTGFSCQR 753
Score = 97.5 bits (232), Expect = 8e-19
Identities = 97/355 (27%), Positives = 130/355 (36%), Gaps = 49/355 (13%)
Query: 438 ICEDGYYSPECK-NCE-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTC 494
+C D + +C C+ C G+ D C C ++G CN+ C +
Sbjct: 405 VCLDDSFGHDCSLTCDDCRNGGTCLLGLD----GCDCPEGWTGLICNETCPPDTFGKNCS 460
Query: 495 KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPT 553
C+C GT CD V+G C C G G C D C GYY + ++ CNC
Sbjct: 461 FSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKK-----CNCANR 511
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCH 612
G G C C G C P + P C S C +CD +G C
Sbjct: 512 GRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGC-SEECQCVQPHTQSCDKRDGSCS 567
Query: 613 CKSNFDGAKCDTCREQFYNYPAC-EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
CK+ F G +C E Y P C + C C P GV C SV +C QG
Sbjct: 568 CKAGFRGERCQAECELGYFGPGCWQACTC-PVGV-----ACDSVSGECGKRCPAGFQGED 621
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD-QCLD 730
C QE P G NC+ + + C+ +GQC C C+ C +
Sbjct: 622 CG---------QEC-PVGTFGVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCEADCPE 670
Query: 731 GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
G + L ++ C C CD TG C C G RC A ++
Sbjct: 671 GRWGLGCQEI--CPACQHAA------RCDPETGACLCLPGFVGSRCQDVCPAGWY 717
Score = 96.7 bits (230), Expect = 1e-18
Identities = 76/240 (31%), Positives = 108/240 (45%), Gaps = 37/240 (15%)
Query: 1827 ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
+L+CD NG C G G C+ C G+ G+ + + K NCS + + Q
Sbjct: 416 SLTCDDCRNGG----TCLLGLDG--CD-CPEGWTGLICNETCPPDTFGK--NCSFSCSCQ 466
Query: 1887 DPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNC-TACICDEFGMADCDSTT 1944
+ G+CDS+ G C +C +G C + C G+YG K+C C C G C
Sbjct: 467 NGGTCDSVTGAC-RCPPGVSGTNCEDGCPKGYYG-----KHCRKKCNCANRGR--CHRLY 518
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKGVTG 2003
G C+C PG+ G C P W G GC+ C C + + CD +G C C G G
Sbjct: 519 GACLCDPGLYGRFCHLTCPP-WAF--GPGCSEECQC-VQPHTQSCDKRDGSCSCKAGFRG 574
Query: 2004 KQCD-QCAAGFWNYTKDGC-DHCNCNTGYSVGFMCNA-TGQC--ECLPGVIGEKC-DRCP 2057
++C +C G++ GC C C VG C++ +G+C C G GE C CP
Sbjct: 575 ERCQAECELGYFG---PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECP 627
Score = 89.4 bits (212), Expect = 2e-16
Identities = 55/163 (33%), Positives = 73/163 (44%), Gaps = 19/163 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAICDD-NGMCICPKNVEG 1408
C+ G C C +G C+ C G +G PNC C C A CD G C+CP G
Sbjct: 992 CDAATGACRCPTGFLGTDCNLTCPQGRFG-PNCTHVCGCGQGAACDPVTGTCLCPPGRAG 1050
Query: 1409 ENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HCV 1466
C+R P F V GC+ C+C G+ C A +G C+C GR C+ C
Sbjct: 1051 VRCERGCPQN-RFGV--GCEHTCSCRNGGL------CHASNGSCSCGLGWTGRHCELACP 1101
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
PG Y +C+C+ + T C+ T C C GQAC+
Sbjct: 1102 PGRYGAACHLECSCHNNST----CEPATGTCRCGPGFYGQACE 1140
Score = 86.6 bits (205), Expect = 1e-15
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C++ G C C P V G C C GYYG +CR C+C + C G C+C + G
Sbjct: 471 CDSVTGACRCPPGVSGTNCEDGCPKGYYG-KHCRKKCNCANRGRCHRLYGACLCDPGLYG 529
Query: 1409 ENCD-RCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HC 1465
C C P+ F GC ++C C V + C+ G C+C+ RG C C
Sbjct: 530 RFCHLTCPPWAFG----PGCSEECQC----VQPHTQSCDKRDGSCSCKAGFRGERCQAEC 581
Query: 1466 VPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQC--YCKTNVRGQAC-DTCKEEYFNLQDD 1521
G++ P C+Q CTC CD + +C C +G+ C C F +
Sbjct: 582 ELGYFG-PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCS 636
Query: 1522 NPDGCTKCFCFGKTTRC 1538
+ C C G T +C
Sbjct: 637 SSCSCGGAPCHGVTGQC 653
Score = 81.8 bits (193), Expect = 4e-14
Identities = 59/194 (30%), Positives = 80/194 (41%), Gaps = 20/194 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPST-AICDD-NGMCICPKNVE 1407
C+ G C C P G +C AC TG++G P+C PC+C + CD +G+C+C
Sbjct: 733 CHPATGHCSCAPGWTGFSCQRACDTGHWG-PDCSHPCNCSAGHGSCDAISGLCLCEAGYV 791
Query: 1408 GENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCV 1466
G C++ P +F GC+ C C + C+ SG C C RG C+H
Sbjct: 792 GPRCEQQCPQG-HFGP--GCEQRCQCQ------HGAACDHVSGACTCPAGWRGTFCEHAC 842
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYFNLQDDNPDG 1525
P + DC + CN T CD C C RG C + C + G
Sbjct: 843 PAGFFGLDC-RSACN--CTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGG 899
Query: 1526 CTK-CFCFGKTTRC 1538
C C T RC
Sbjct: 900 CLNGGLCDPHTGRC 913
Score = 81.8 bits (193), Expect = 4e-14
Identities = 80/260 (30%), Positives = 97/260 (37%), Gaps = 51/260 (19%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGIC------------ 1781
C+CP + G CEQ C G Y G C C NG S CD TG C
Sbjct: 956 CRCPPGFTGSGCEQGCPPGRYG--PGCEQLCGCLNGGS--CDAATGACRCPTGFLGTDCN 1011
Query: 1782 LNCADNTIGDHCEF---CMSGYHGDATVGT---PRDCLICACPMPYPSNNFALSCDLS-- 1833
L C G +C C G D GT P C P N F + C+ +
Sbjct: 1012 LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1071
Query: 1834 -ENGSLI-----SCNCQPGYGGARCEY-CAAGYYGIP--EDTDLHTGDYCKPCNCSGNIN 1884
NG L SC+C G+ G CE C G YG + H C+P +
Sbjct: 1072 CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1131
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDST 1943
P G C + +GA CNL C G +G + CT CD G ADCD
Sbjct: 1132 PGFYGQA---------CEHRRSGATCNLDCRRGQFGPS-----CTLH-CDCGGGADCDPV 1176
Query: 1944 TGTCVCRPGVIGEKCDRCAP 1963
+G C C G +G C P
Sbjct: 1177 SGQCHCVDGYMGPTCREGGP 1196
Score = 73.7 bits (173), Expect = 1e-11
Identities = 53/186 (28%), Positives = 73/186 (39%), Gaps = 23/186 (12%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRP-CHCPSTAIC 1394
+ PC C + C+ G C C+ +G C C G++G P C C C A C
Sbjct: 765 SHPCNCS---AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG-PGCEQRCQCQHGAAC 820
Query: 1395 DD-NGMCICPKNVEGENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
D +G C CP G C+ C F D + C NC G C+A +G C
Sbjct: 821 DHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC---NCTA-GAA-----CDAVNGSCL 871
Query: 1453 CRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT- 1510
C RG C + C+P + C G +CD +T +C C G C +
Sbjct: 872 CPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGG----LCDPHTGRCLCPAGWTGDKCQSP 927
Query: 1511 CKEEYF 1516
C +F
Sbjct: 928 CLRGWF 933
Score = 73.7 bits (173), Expect = 1e-11
Identities = 53/195 (27%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G+C C G C S C G++G + C CP A C G C CP G
Sbjct: 906 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGS 965
Query: 1410 NCDR-CKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C++ C P + GC+ C C N C+A +G C C G C+ P
Sbjct: 966 GCEQGCPPGRYG----PGCEQLCGCL------NGGSCDAATGACRCPTGFLGTDCNLTCP 1015
Query: 1468 GHYAFPDC-YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT-CKEEYFNLQDDNPDG 1525
P+C + C C + CD T C C G C+ C + F + ++
Sbjct: 1016 QGRFGPNCTHVCGCGQGA----ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1071
Query: 1526 CTK-CFCFGKTTRCS 1539
C C CS
Sbjct: 1072 CRNGGLCHASNGSCS 1086
Score = 72.9 bits (171), Expect = 2e-11
Identities = 57/190 (30%), Positives = 77/190 (40%), Gaps = 23/190 (12%)
Query: 1889 GSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGT 1946
G+C + D C G CN C P +G KNC+ +C C G CDS TG
Sbjct: 426 GTC-LLGLDGCDCPEGWTGLICNETCPPDTFG-----KNCSFSCSCQNGGT--CDSVTGA 477
Query: 1947 CVCRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQ 2005
C C PGV G C D C ++G + CNC + +C G C C G+ G+
Sbjct: 478 CRCPPGVSGTNCEDGCPKGYYGKHCR---KKCNC---ANRGRCHRLYGACLCDPGLYGRF 531
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP 2064
C W + + C C ++ C+ G C C G GE+C E P
Sbjct: 532 C-HLTCPPWAFGPGCSEECQCVQPHTQS--CDKRDGSCSCKAGFRGERCQAECELGYFGP 588
Query: 2065 QEGCLECDSC 2074
GC + +C
Sbjct: 589 --GCWQACTC 596
Score = 62.9 bits (146), Expect = 2e-08
Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 18/182 (9%)
Query: 1352 CNTFGGQCP--CKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEG 1408
C++ G+C C G C C G +G C C G C CP G
Sbjct: 602 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 661
Query: 1409 ENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
E+C+ C + Q C C + +C+ ++G C C G C P
Sbjct: 662 EDCEADCPEGRWGLGCQEICPACQ--------HAARCDPETGACLCLPGFVGSRCQDVCP 713
Query: 1468 GHYAFPDCY-QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNPDG 1525
+ P C +C+C G C T C C G +C C ++ +P
Sbjct: 714 AGWYGPSCQTRCSCANDGH----CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 769
Query: 1526 CT 1527
C+
Sbjct: 770 CS 771
Score = 62.9 bits (146), Expect = 2e-08
Identities = 46/168 (27%), Positives = 63/168 (37%), Gaps = 22/168 (13%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
C+ G C C P G C C +G C C + +C NG C C G
Sbjct: 1035 CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGR 1094
Query: 1410 NCD-RCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
+C+ C P + C +C+C+ N CE +G C C G+ C+H
Sbjct: 1095 HCELACPPGRYG----AACHLECSCH------NNSTCEPATGTCRCGPGFYGQACEHRRS 1144
Query: 1468 GHYAFPDC----YQCTCNRH---GTTYDVCDQNTAQCYCKTNVRGQAC 1508
G DC + +C H G D CD + QC+C G C
Sbjct: 1145 GATCNLDCRRGQFGPSCTLHCDCGGGAD-CDPVSGQCHCVDGYMGPTC 1191
Score = 50.4 bits (115), Expect = 1e-04
Identities = 62/240 (25%), Positives = 80/240 (33%), Gaps = 36/240 (15%)
Query: 1869 HTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNLCAPGFYGDAIFSKNC 1927
H G P + +G+ P D C + NG C +CVN C C PGF S+ C
Sbjct: 40 HLGQAGYPVS-AGDQRP-DVDECRTHNGGCQHRCVNTPGSYLCE-CKPGFRLHT-DSRTC 95
Query: 1928 TACICDEFGMADCDS-------TTGTCVCRPGV-IGEKCDRCAPDHWGLNTGLGCTPCNC 1979
A G C T C CRPG + E C N C C
Sbjct: 96 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RC 154
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN-----YTKDGCDHCNCNTGYSVGF 2034
+ +C+ G A G + D+CAAG G C C+ GY +G
Sbjct: 155 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGA 214
Query: 2035 ---MC-----NATGQCECLPGVIGEKCDR--------CPERWVL-IPQEGCLECDSCTDA 2077
C CE G C CP + L Q C++ D C D+
Sbjct: 215 DGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS 274
Score = 48.8 bits (111), Expect = 4e-04
Identities = 87/343 (25%), Positives = 119/343 (34%), Gaps = 67/343 (19%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQH---NTEGINCNKCRPTY 344
C PC H + Y ++R +D + GG CQH NT G +C+P +
Sbjct: 36 CYPC----HLGQAGYPVSAGDQRPDVDECRTHNGG-----CQHRCVNTPGSYLCECKPGF 86
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTGNCEEES---GRCECRPEFQ-PPDCSSCAYGYFDY 400
R C +C + + RC+CRP FQ D C
Sbjct: 87 RLHTDSR--TCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV------ 138
Query: 401 PNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYA----GKSCE-ICEDGYYSPECKNCEC 453
PC N NG+ C GL C C Y GK+CE + E +C +
Sbjct: 139 -RRSPC-ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCL 196
Query: 454 NTVGSVSYVCD---KLTGDCTCKSKYSGRTCNQCQAGY------YNYPTCKP-CNCDTS- 502
NT GS VC +L D + N C+A ++ + P C C
Sbjct: 197 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 256
Query: 503 --GTEPSICDDVSG-------QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
T+ C DV Q +C GG C C +GY + G C C+
Sbjct: 257 ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECG-CYAGYRLSADG-------CGCE-- 306
Query: 554 GSTSTSCSADGKC--NCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
S+ G C +C G QC C GY + D C+
Sbjct: 307 -DVDECASSRGGCEHHCTNLAGSFQC-SCEAGYRLHEDRRGCS 347
Score = 48.8 bits (111), Expect = 4e-04
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 19/133 (14%)
Query: 1383 CRPCHCPSTAICDDNGMCICPKNVEGENCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGN 1440
C C T + +G C CP+ G C+ C P TF + C C+C G
Sbjct: 419 CDDCRNGGTCLLGLDG-CDCPEGWTGLICNETCPPDTFG----KNCSFSCSCQNGGT--- 470
Query: 1441 QLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
C++ +G C C V G C D C G+Y +C C G C + C C
Sbjct: 471 ---CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR----CHRLYGACLC 523
Query: 1500 KTNVRGQACD-TC 1511
+ G+ C TC
Sbjct: 524 DPGLYGRFCHLTC 536
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 146 bits (353), Expect = 2e-33
Identities = 165/619 (26%), Positives = 226/619 (36%), Gaps = 97/619 (15%)
Query: 225 ISIGGRCMCNG---HADTCEPADPAGNLNI-LVCRCQHNTCGPQCNKCCSGFEQKKWRIS 280
++ C C G H T + P G C G C + C + R
Sbjct: 633 VNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA-RCD 691
Query: 281 QNWDRFSCEP----CNCHNHTTECTYDPEIDEKRLSLDINGR-YEGGGKCLNCQHNTEGI 335
C P C + Y P + R S +G + G C +C G
Sbjct: 692 PETGACLCLPGFVGSRCQDVCPAGWYGPSC-QTRCSCANDGHCHPATGHC-SCAPGWTGF 749
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS-CA 394
+C + T + W D PC C G+C+ SG C C + P C C
Sbjct: 750 SCQRACDTGH------WGP-DCSHPCNCSA--GHGSCDAISGLCLCEAGYVGPRCEQQCP 800
Query: 395 YGYFDYPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPECKN-C 451
G+F P C+ C C G C G C C + G CE C G++ +C++ C
Sbjct: 801 QGHFG-PGCEQRCQCQ----HGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC 855
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKPCNCDTSG--TEPSI 508
C T G+ CD + G C C + G C +C P C SG +
Sbjct: 856 NC-TAGAA---CDAVNGSCLCPAGRRGPRCAEKC------LPRDVRAGCRHSGGCLNGGL 905
Query: 509 CDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCN 567
CD +G+C+C AG+ G +C CL G++ + + C+C P + G C
Sbjct: 906 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR-----CSCPPGAACH---HVTGACR 957
Query: 568 CLTNFGGAQCDQ-CSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD- 623
C F G+ C+Q C PG Y P C C C GS CD G C C + F G C+
Sbjct: 958 CPPGFTGSGCEQGCPPGRYG-PGCEQLCGCLNGGS----CDAATGACRCPTGFLGTDCNL 1012
Query: 624 TCREQFYNYPACEECNC------DP----------RGVTASFAGCGSVPAGELCQ--CKD 665
TC + + C C DP R GC G C+ C
Sbjct: 1013 TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSC 1072
Query: 666 RVQGRICN----DCK-PLYWNLQEYN---PFGCEQCNCNLAGTLNSLGACNTKSGQCVCK 717
R G +C+ C L W + P G C+L + ++ C +G C C
Sbjct: 1073 R-NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1131
Query: 718 QHVGERQCDQCLDGFY-RLQTN-DVFG--CTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
+ C+ G L FG CT CD GG D CD +GQCHC G
Sbjct: 1132 PGFYGQACEHRRSGATCNLDCRRGQFGPSCT-LHCDCGGGAD--CDPVSGQCHCVDGYMG 1188
Query: 774 RRCDQ--PIRAHYFPTLHQ 790
C + P+R P+L Q
Sbjct: 1189 PTCREGGPLRLPENPSLAQ 1207
Score = 145 bits (352), Expect = 2e-33
Identities = 138/485 (28%), Positives = 185/485 (38%), Gaps = 83/485 (17%)
Query: 322 GGKCL------NCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQ-PCQCDPHFSTGNCEE 374
GG CL +C G+ CN+ P +GK C C C + G C+
Sbjct: 425 GGTCLLGLDGCDCPEGWTGLICNETCPP--DTFGKN------CSFSCSCQ---NGGTCDS 473
Query: 375 ESGRCECRPEFQPPDCSS-CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAG 433
+G C C P +C C GY+ K C C G C G C C G
Sbjct: 474 VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRG----RCHRLYGACLCDPGLYG 529
Query: 434 KSCEI-CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNY 491
+ C + C + P C EC V + CDK G C+CK+ + G C +C+ GY+
Sbjct: 530 RFCHLTCPPWAFGPGCSE-ECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGP 588
Query: 492 PTCKPCNCDTSGTEPSICDDVSGQC--ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPC 548
+ C C CD VSG+C C AGF G C Q C G + C
Sbjct: 589 GCWQACTCPVG----VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGA 644
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPDCLSCN--CDVSGSIGSTC 605
C G T G+C C G C+ C G + L C C
Sbjct: 645 PCH--GVT-------GQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHAARCD 691
Query: 606 DDNGLCHCKSNFDGAKC-DTCREQFYNYPACE-ECNCDPRGVTASFAGCGSVPAGELCQC 663
+ G C C F G++C D C +Y P+C+ C+C A+ C PA C C
Sbjct: 692 PETGACLCLPGFVGSRCQDVCPAGWYG-PSCQTRCSC------ANDGHCH--PATGHCSC 742
Query: 664 KDRVQGRIC-NDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG 721
G C C +W P CNC+ AG G+C+ SG C+C+ +VG
Sbjct: 743 APGWTGFSCQRACDTGHW-----GPDCSHPCNCS-AGH----GSCDAISGLCLCEAGYVG 792
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
R QC G + GC + C C G + CD +G C C + G C+
Sbjct: 793 PRCEQQCPQGHFGP------GCEQRCQCQHGAA----CDHVSGACTCPAGWRGTFCEHAC 842
Query: 781 RAHYF 785
A +F
Sbjct: 843 PAGFF 847
Score = 125 bits (301), Expect = 3e-27
Identities = 106/326 (32%), Positives = 133/326 (40%), Gaps = 62/326 (19%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C CP RG C E+C R C G CD +TG CL C GD C+
Sbjct: 870 CLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGG---LCDPHTGRCL-CPAGWTGDKCQ 925
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C+ G+ G+A C+CP +C +C C PG+ G+ CE
Sbjct: 926 SPCLRGWFGEACAQR------CSCPP-------GAACHHVTG----ACRCPPGFTGSGCE 968
Query: 1854 Y-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
C G YG P L C C GSCD+ G C +C G CNL
Sbjct: 969 QGCPPGRYG-PGCEQL--------CGCLNG------GSCDAATGAC-RCPTGFLGTDCNL 1012
Query: 1913 CAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
P F NCT C C + G A CD TGTC+C PG G +C+R P + G
Sbjct: 1013 TCP----QGRFGPNCTHVCGCGQ-GAA-CDPVTGTCLCPPGRAGVRCERGCPQN---RFG 1063
Query: 1972 LGCT-PCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCDHCNCNTG 2029
+GC C+C C NG C C G TG+ C+ C G Y C+C+
Sbjct: 1064 VGCEHTCSC---RNGGLCHASNGSCSCGLGWTGRHCELACPPG--RYGAACHLECSCHNN 1118
Query: 2030 YSVGFMCN-ATGQCECLPGVIGEKCD 2054
+ C ATG C C PG G+ C+
Sbjct: 1119 ST----CEPATGTCRCGPGFYGQACE 1140
Score = 113 bits (273), Expect = 9e-24
Identities = 96/332 (28%), Positives = 130/332 (39%), Gaps = 60/332 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C G C + G CQC H+ CD G C +C G+ C+
Sbjct: 521 CLCDPGLYGRFCHLTCPP-WAFGPGCSEECQCVQPHTQSCDKRDGSC-SCKAGFRGERCQ 578
Query: 1795 F-CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC- 1852
C GY G P C CP+ ++CD S +G C G+ G C
Sbjct: 579 AECELGYFG------PGCWQACTCPV-------GVACD-SVSGEC-GKRCPAGFQGEDCG 623
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ C G +G+ + C+C G C + G C +C G C
Sbjct: 624 QECPVGTFGV---------NCSSSCSCGG-------APCHGVTGQC-RCPPGRTGEDCEA 666
Query: 1913 -CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
C G +G + C AC A CD TG C+C PG +G +C P W G
Sbjct: 667 DCPEGRWGLGC-QEICPACQ----HAARCDPETGACLCLPGFVGSRCQDVCPAGW---YG 718
Query: 1972 LGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ-CAAGFWNYTKDGCDH-CNCNT 2028
C T C+C + C G C CA G TG C + C G W C H CNC+
Sbjct: 719 PSCQTRCSC---ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG---PDCSHPCNCSA 772
Query: 2029 GYSVGFMCNA-TGQCECLPGVIGEKCD-RCPE 2058
G+ C+A +G C C G +G +C+ +CP+
Sbjct: 773 GHG---SCDAISGLCLCEAGYVGPRCEQQCPQ 801
Score = 113 bits (273), Expect = 9e-24
Identities = 109/364 (29%), Positives = 141/364 (38%), Gaps = 56/364 (15%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C + G SC++ C GH+ PC C+ CD +G+CL C +G CE
Sbjct: 740 CSCAPGWTGFSCQRACDTGHWGPDCSH--PCNCSAGHGSCDAISGLCL-CEAGYVGPRCE 796
Query: 1795 F-CMSGYHGDATV-------GTPRDCL--ICACPMPYPSNNFALSCDLSENG--SLISCN 1842
C G+ G G D + C CP + +C G +CN
Sbjct: 797 QQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACN 856
Query: 1843 CQPGYGGARCE------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
C GA C+ C AG G D C SG + G CD G
Sbjct: 857 CT---AGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGC--LNGGLCDPHTG 911
Query: 1897 DCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG 1955
CL C G C C G++G+A + C C G A C TG C C PG G
Sbjct: 912 RCL-CPAGWTGDKCQSPCLRGWFGEACAQR----CSCPP-GAA-CHHVTGACRCPPGFTG 964
Query: 1956 EKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGF 2013
C++ C P + G GC CG + + CD G CRC G G C+ C G
Sbjct: 965 SGCEQGCPPGRY----GPGCEQL-CGCLNGGS-CDAATGACRCPTGFLGTDCNLTCPQGR 1018
Query: 2014 WNYTKDGCDH-CNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDR-CPERWVLIPQEGCLE 2070
+ C H C C G + C+ TG C C PG G +C+R CP+ + GC
Sbjct: 1019 FG---PNCTHVCGCGQGAA----CDPVTGTCLCPPGRAGVRCERGCPQNRFGV---GCEH 1068
Query: 2071 CDSC 2074
SC
Sbjct: 1069 TCSC 1072
Score = 113 bits (271), Expect = 2e-23
Identities = 107/350 (30%), Positives = 130/350 (37%), Gaps = 55/350 (15%)
Query: 1733 VEECQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
++ C CP + GL C E C + F CQ G CD TG C C G
Sbjct: 432 LDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG---TCDSVTGAC-RCPPGVSGT 487
Query: 1792 HCE-FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
+CE C GY+G R CA A CD G C P G
Sbjct: 488 NCEDGCPKGYYGKHC----RKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP 543
Query: 1851 RCEYCAAGYYGIPEDTDLHTGD-YCKP------CNCSGNINPQDPG-----------SCD 1892
C + D G CK C + PG +CD
Sbjct: 544 GCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACD 603
Query: 1893 SINGDCLK-CVNNTAGAACNL-CAPGFYGDAIFSKNC-TACICDEFGMADCDSTTGTCVC 1949
S++G+C K C G C C G +G NC ++C C G A C TG C C
Sbjct: 604 SVSGECGKRCPAGFQGEDCGQECPVGTFG-----VNCSSSCSC---GGAPCHGVTGQCRC 655
Query: 1950 RPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC-D 2007
PG GE C+ C W GLGC C + +CD + G C C G G +C D
Sbjct: 656 PPGRTGEDCEADCPEGRW----GLGCQEI-CPACQHAARCDPETGACLCLPGFVGSRCQD 710
Query: 2008 QCAAGFWNYTKDGCDHCNC-NTGYSVGFMCN-ATGQCECLPGVIGEKCDR 2055
C AG W Y C+C N G+ C+ ATG C C PG G C R
Sbjct: 711 VCPAG-W-YGPSCQTRCSCANDGH-----CHPATGHCSCAPGWTGFSCQR 753
Score = 97.5 bits (232), Expect = 8e-19
Identities = 97/355 (27%), Positives = 130/355 (36%), Gaps = 49/355 (13%)
Query: 438 ICEDGYYSPECK-NCE-CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTC 494
+C D + +C C+ C G+ D C C ++G CN+ C +
Sbjct: 405 VCLDDSFGHDCSLTCDDCRNGGTCLLGLD----GCDCPEGWTGLICNETCPPDTFGKNCS 460
Query: 495 KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPT 553
C+C GT CD V+G C C G G C D C GYY + ++ CNC
Sbjct: 461 FSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKK-----CNCANR 511
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLCH 612
G G C C G C P + P C S C +CD +G C
Sbjct: 512 GRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGC-SEECQCVQPHTQSCDKRDGSCS 567
Query: 613 CKSNFDGAKCDTCREQFYNYPAC-EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
CK+ F G +C E Y P C + C C P GV C SV +C QG
Sbjct: 568 CKAGFRGERCQAECELGYFGPGCWQACTC-PVGV-----ACDSVSGECGKRCPAGFQGED 621
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD-QCLD 730
C QE P G NC+ + + C+ +GQC C C+ C +
Sbjct: 622 CG---------QEC-PVGTFGVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCEADCPE 670
Query: 731 GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
G + L ++ C C CD TG C C G RC A ++
Sbjct: 671 GRWGLGCQEI--CPACQHAA------RCDPETGACLCLPGFVGSRCQDVCPAGWY 717
Score = 96.7 bits (230), Expect = 1e-18
Identities = 76/240 (31%), Positives = 108/240 (45%), Gaps = 37/240 (15%)
Query: 1827 ALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQ 1886
+L+CD NG C G G C+ C G+ G+ + + K NCS + + Q
Sbjct: 416 SLTCDDCRNGG----TCLLGLDG--CD-CPEGWTGLICNETCPPDTFGK--NCSFSCSCQ 466
Query: 1887 DPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNC-TACICDEFGMADCDSTT 1944
+ G+CDS+ G C +C +G C + C G+YG K+C C C G C
Sbjct: 467 NGGTCDSVTGAC-RCPPGVSGTNCEDGCPKGYYG-----KHCRKKCNCANRGR--CHRLY 518
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKGVTG 2003
G C+C PG+ G C P W G GC+ C C + + CD +G C C G G
Sbjct: 519 GACLCDPGLYGRFCHLTCPP-WAF--GPGCSEECQC-VQPHTQSCDKRDGSCSCKAGFRG 574
Query: 2004 KQCD-QCAAGFWNYTKDGC-DHCNCNTGYSVGFMCNA-TGQC--ECLPGVIGEKC-DRCP 2057
++C +C G++ GC C C VG C++ +G+C C G GE C CP
Sbjct: 575 ERCQAECELGYFG---PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECP 627
Score = 89.4 bits (212), Expect = 2e-16
Identities = 55/163 (33%), Positives = 73/163 (44%), Gaps = 19/163 (11%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAICDD-NGMCICPKNVEG 1408
C+ G C C +G C+ C G +G PNC C C A CD G C+CP G
Sbjct: 992 CDAATGACRCPTGFLGTDCNLTCPQGRFG-PNCTHVCGCGQGAACDPVTGTCLCPPGRAG 1050
Query: 1409 ENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HCV 1466
C+R P F V GC+ C+C G+ C A +G C+C GR C+ C
Sbjct: 1051 VRCERGCPQN-RFGV--GCEHTCSCRNGGL------CHASNGSCSCGLGWTGRHCELACP 1101
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
PG Y +C+C+ + T C+ T C C GQAC+
Sbjct: 1102 PGRYGAACHLECSCHNNST----CEPATGTCRCGPGFYGQACE 1140
Score = 86.6 bits (205), Expect = 1e-15
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEG 1408
C++ G C C P V G C C GYYG +CR C+C + C G C+C + G
Sbjct: 471 CDSVTGACRCPPGVSGTNCEDGCPKGYYG-KHCRKKCNCANRGRCHRLYGACLCDPGLYG 529
Query: 1409 ENCD-RCKPYTFNFDVQRGC-DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD-HC 1465
C C P+ F GC ++C C V + C+ G C+C+ RG C C
Sbjct: 530 RFCHLTCPPWAFG----PGCSEECQC----VQPHTQSCDKRDGSCSCKAGFRGERCQAEC 581
Query: 1466 VPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQC--YCKTNVRGQAC-DTCKEEYFNLQDD 1521
G++ P C+Q CTC CD + +C C +G+ C C F +
Sbjct: 582 ELGYFG-PGCWQACTC----PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCS 636
Query: 1522 NPDGCTKCFCFGKTTRC 1538
+ C C G T +C
Sbjct: 637 SSCSCGGAPCHGVTGQC 653
Score = 81.8 bits (193), Expect = 4e-14
Identities = 59/194 (30%), Positives = 80/194 (41%), Gaps = 20/194 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPST-AICDD-NGMCICPKNVE 1407
C+ G C C P G +C AC TG++G P+C PC+C + CD +G+C+C
Sbjct: 733 CHPATGHCSCAPGWTGFSCQRACDTGHWG-PDCSHPCNCSAGHGSCDAISGLCLCEAGYV 791
Query: 1408 GENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCV 1466
G C++ P +F GC+ C C + C+ SG C C RG C+H
Sbjct: 792 GPRCEQQCPQG-HFGP--GCEQRCQCQ------HGAACDHVSGACTCPAGWRGTFCEHAC 842
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYFNLQDDNPDG 1525
P + DC + CN T CD C C RG C + C + G
Sbjct: 843 PAGFFGLDC-RSACN--CTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGG 899
Query: 1526 CTK-CFCFGKTTRC 1538
C C T RC
Sbjct: 900 CLNGGLCDPHTGRC 913
Score = 81.8 bits (193), Expect = 4e-14
Identities = 80/260 (30%), Positives = 97/260 (37%), Gaps = 51/260 (19%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQC-NGHSDQCDVNTGIC------------ 1781
C+CP + G CEQ C G Y G C C NG S CD TG C
Sbjct: 956 CRCPPGFTGSGCEQGCPPGRYG--PGCEQLCGCLNGGS--CDAATGACRCPTGFLGTDCN 1011
Query: 1782 LNCADNTIGDHCEF---CMSGYHGDATVGT---PRDCLICACPMPYPSNNFALSCDLS-- 1833
L C G +C C G D GT P C P N F + C+ +
Sbjct: 1012 LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1071
Query: 1834 -ENGSLI-----SCNCQPGYGGARCEY-CAAGYYGIP--EDTDLHTGDYCKPCNCSGNIN 1884
NG L SC+C G+ G CE C G YG + H C+P +
Sbjct: 1072 CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1131
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDST 1943
P G C + +GA CNL C G +G + CT CD G ADCD
Sbjct: 1132 PGFYGQA---------CEHRRSGATCNLDCRRGQFGPS-----CTLH-CDCGGGADCDPV 1176
Query: 1944 TGTCVCRPGVIGEKCDRCAP 1963
+G C C G +G C P
Sbjct: 1177 SGQCHCVDGYMGPTCREGGP 1196
Score = 73.7 bits (173), Expect = 1e-11
Identities = 53/186 (28%), Positives = 73/186 (39%), Gaps = 23/186 (12%)
Query: 1337 ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRP-CHCPSTAIC 1394
+ PC C + C+ G C C+ +G C C G++G P C C C A C
Sbjct: 765 SHPCNCS---AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG-PGCEQRCQCQHGAAC 820
Query: 1395 DD-NGMCICPKNVEGENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
D +G C CP G C+ C F D + C NC G C+A +G C
Sbjct: 821 DHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC---NCTA-GAA-----CDAVNGSCL 871
Query: 1453 CRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT- 1510
C RG C + C+P + C G +CD +T +C C G C +
Sbjct: 872 CPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGG----LCDPHTGRCLCPAGWTGDKCQSP 927
Query: 1511 CKEEYF 1516
C +F
Sbjct: 928 CLRGWF 933
Score = 73.7 bits (173), Expect = 1e-11
Identities = 53/195 (27%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCRPCHCPSTAICDD-NGMCICPKNVEGE 1409
C+ G+C C G C S C G++G + C CP A C G C CP G
Sbjct: 906 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGS 965
Query: 1410 NCDR-CKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C++ C P + GC+ C C N C+A +G C C G C+ P
Sbjct: 966 GCEQGCPPGRYG----PGCEQLCGCL------NGGSCDAATGACRCPTGFLGTDCNLTCP 1015
Query: 1468 GHYAFPDC-YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT-CKEEYFNLQDDNPDG 1525
P+C + C C + CD T C C G C+ C + F + ++
Sbjct: 1016 QGRFGPNCTHVCGCGQGA----ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1071
Query: 1526 CTK-CFCFGKTTRCS 1539
C C CS
Sbjct: 1072 CRNGGLCHASNGSCS 1086
Score = 72.9 bits (171), Expect = 2e-11
Identities = 57/190 (30%), Positives = 77/190 (40%), Gaps = 23/190 (12%)
Query: 1889 GSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCT-ACICDEFGMADCDSTTGT 1946
G+C + D C G CN C P +G KNC+ +C C G CDS TG
Sbjct: 426 GTC-LLGLDGCDCPEGWTGLICNETCPPDTFG-----KNCSFSCSCQNGGT--CDSVTGA 477
Query: 1947 CVCRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQ 2005
C C PGV G C D C ++G + CNC + +C G C C G+ G+
Sbjct: 478 CRCPPGVSGTNCEDGCPKGYYGKHCR---KKCNC---ANRGRCHRLYGACLCDPGLYGRF 531
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIP 2064
C W + + C C ++ C+ G C C G GE+C E P
Sbjct: 532 C-HLTCPPWAFGPGCSEECQCVQPHTQS--CDKRDGSCSCKAGFRGERCQAECELGYFGP 588
Query: 2065 QEGCLECDSC 2074
GC + +C
Sbjct: 589 --GCWQACTC 596
Score = 62.9 bits (146), Expect = 2e-08
Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 18/182 (9%)
Query: 1352 CNTFGGQCP--CKPNVIGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEG 1408
C++ G+C C G C C G +G C C G C CP G
Sbjct: 602 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 661
Query: 1409 ENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
E+C+ C + Q C C + +C+ ++G C C G C P
Sbjct: 662 EDCEADCPEGRWGLGCQEICPACQ--------HAARCDPETGACLCLPGFVGSRCQDVCP 713
Query: 1468 GHYAFPDCY-QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNPDG 1525
+ P C +C+C G C T C C G +C C ++ +P
Sbjct: 714 AGWYGPSCQTRCSCANDGH----CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 769
Query: 1526 CT 1527
C+
Sbjct: 770 CS 771
Score = 62.9 bits (146), Expect = 2e-08
Identities = 46/168 (27%), Positives = 63/168 (37%), Gaps = 22/168 (13%)
Query: 1352 CNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRPCHCPSTAICD-DNGMCICPKNVEGE 1409
C+ G C C P G C C +G C C + +C NG C C G
Sbjct: 1035 CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGR 1094
Query: 1410 NCD-RCKPYTFNFDVQRGCD-DCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
+C+ C P + C +C+C+ N CE +G C C G+ C+H
Sbjct: 1095 HCELACPPGRYG----AACHLECSCH------NNSTCEPATGTCRCGPGFYGQACEHRRS 1144
Query: 1468 GHYAFPDC----YQCTCNRH---GTTYDVCDQNTAQCYCKTNVRGQAC 1508
G DC + +C H G D CD + QC+C G C
Sbjct: 1145 GATCNLDCRRGQFGPSCTLHCDCGGGAD-CDPVSGQCHCVDGYMGPTC 1191
Score = 50.4 bits (115), Expect = 1e-04
Identities = 62/240 (25%), Positives = 80/240 (33%), Gaps = 36/240 (15%)
Query: 1869 HTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNLCAPGFYGDAIFSKNC 1927
H G P + +G+ P D C + NG C +CVN C C PGF S+ C
Sbjct: 40 HLGQAGYPVS-AGDQRP-DVDECRTHNGGCQHRCVNTPGSYLCE-CKPGFRLHT-DSRTC 95
Query: 1928 TACICDEFGMADCDS-------TTGTCVCRPGV-IGEKCDRCAPDHWGLNTGLGCTPCNC 1979
A G C T C CRPG + E C N C C
Sbjct: 96 LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-RC 154
Query: 1980 GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN-----YTKDGCDHCNCNTGYSVGF 2034
+ +C+ G A G + D+CAAG G C C+ GY +G
Sbjct: 155 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGA 214
Query: 2035 ---MC-----NATGQCECLPGVIGEKCDR--------CPERWVL-IPQEGCLECDSCTDA 2077
C CE G C CP + L Q C++ D C D+
Sbjct: 215 DGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS 274
Score = 48.8 bits (111), Expect = 4e-04
Identities = 87/343 (25%), Positives = 119/343 (34%), Gaps = 67/343 (19%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQH---NTEGINCNKCRPTY 344
C PC H + Y ++R +D + GG CQH NT G +C+P +
Sbjct: 36 CYPC----HLGQAGYPVSAGDQRPDVDECRTHNGG-----CQHRCVNTPGSYLCECKPGF 86
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTGNCEEES---GRCECRPEFQ-PPDCSSCAYGYFDY 400
R C +C + + RC+CRP FQ D C
Sbjct: 87 RLHTDSR--TCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV------ 138
Query: 401 PNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYA----GKSCE-ICEDGYYSPECKNCEC 453
PC N NG+ C GL C C Y GK+CE + E +C +
Sbjct: 139 -RRSPC-ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCL 196
Query: 454 NTVGSVSYVCD---KLTGDCTCKSKYSGRTCNQCQAGY------YNYPTCKP-CNCDTS- 502
NT GS VC +L D + N C+A ++ + P C C
Sbjct: 197 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 256
Query: 503 --GTEPSICDDVSG-------QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
T+ C DV Q +C GG C C +GY + G C C+
Sbjct: 257 ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECG-CYAGYRLSADG-------CGCE-- 306
Query: 554 GSTSTSCSADGKC--NCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
S+ G C +C G QC C GY + D C+
Sbjct: 307 -DVDECASSRGGCEHHCTNLAGSFQC-SCEAGYRLHEDRRGCS 347
Score = 48.8 bits (111), Expect = 4e-04
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 19/133 (14%)
Query: 1383 CRPCHCPSTAICDDNGMCICPKNVEGENCDR-CKPYTFNFDVQRGCD-DCNCNPLGVVGN 1440
C C T + +G C CP+ G C+ C P TF + C C+C G
Sbjct: 419 CDDCRNGGTCLLGLDG-CDCPEGWTGLICNETCPPDTFG----KNCSFSCSCQNGGT--- 470
Query: 1441 QLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
C++ +G C C V G C D C G+Y +C C G C + C C
Sbjct: 471 ---CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR----CHRLYGACLC 523
Query: 1500 KTNVRGQACD-TC 1511
+ G+ C TC
Sbjct: 524 DPGLYGRFCHLTC 536
>X70904-1|CAA50261.1| 414|Homo sapiens Laminin Ah protein.
Length = 414
Score = 144 bits (348), Expect = 7e-33
Identities = 104/365 (28%), Positives = 162/365 (44%), Gaps = 19/365 (5%)
Query: 3308 YRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
Y++G SR E+ L G +I RT G +IFY D+ F+ F+
Sbjct: 61 YQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG-MIFYVS---DQEENDFMTLFLA 116
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSV-TCNTP 3426
+L YMFN G + I S Y+D WH V R G+L +D V E S+
Sbjct: 117 HGRLVYMFNVGHKKLKIRSQEKYSDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 176
Query: 3427 LSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN- 3485
+ P Y GG+ + + + N F GCL L +NG +T + C +
Sbjct: 177 WKIKGPIYLGGVA-PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGP 235
Query: 3486 IEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHG-KKDYMVLEL 3544
+E G YF +T Y+ L E+F +G + I+ EVRPR+++G L+ H +Y+ + +
Sbjct: 236 METGTYF----STEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 291
Query: 3545 LDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA 3604
+ +V+ V NG F + ++ K LCDG WH+I D + +G
Sbjct: 292 KNGQVIVKVNNGIRDFSTS--VTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV-VGP 348
Query: 3605 YT--STDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGA-H 3661
D +++GG + R S + FTGC+R+ V+ PV +A+ GA
Sbjct: 349 LNPKPIDHREPVFVGGVPESLLTPRLAPS-KPFTGCIRHFVIDGHPVSFSKAALVSGAVS 407
Query: 3662 VGVCP 3666
+ CP
Sbjct: 408 INSCP 412
Score = 67.3 bits (157), Expect = 1e-09
Identities = 74/318 (23%), Positives = 141/318 (44%), Gaps = 27/318 (8%)
Query: 2871 NQVLLFFRTYAPNGLIYLVG--EGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
+Q + RT + +G+I+ V E F +L + GR+ ++G+ + + + + Y+D
Sbjct: 84 SQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKK--LKIRSQEKYSD 141
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPS-ADIPSLDTMNFGG--NNKGILQVPDRG 2985
G WH + R + L +D + ES P+ A + GG K + V
Sbjct: 142 GLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINS 201
Query: 2986 ---FDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQL 3042
F GC+ + +NG ++ + S+ + + F+ Y+ V E+ +
Sbjct: 202 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYV----VLDESFNI 257
Query: 3043 TLKFKTA---KPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-----TGLN 3094
LKF+ A +P V ++ + +++ + NG+++V D T
Sbjct: 258 GLKFEIAFEVRPRSSSGTLVHGH--SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ 315
Query: 3095 TYNDSQWHVLTVTHNTSALKLVVD-DFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGS 3153
+ D +WH +TV +++ ++L VD + ++ P P+ + V F+GGV P +++
Sbjct: 316 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV-FVGGV-PESLLTPR 373
Query: 3154 LGSKVPFTGCIGDATING 3171
L PFTGCI I+G
Sbjct: 374 LAPSKPFTGCIRHFVIDG 391
Score = 47.2 bits (107), Expect = 0.001
Identities = 74/359 (20%), Positives = 138/359 (38%), Gaps = 51/359 (14%)
Query: 2658 EMSTSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS 2717
+ + S RT+ G I Y+ + + +D+M + + +G + ++G
Sbjct: 79 DFGAKSQFSIRLRTRSSHGMIFYVSDQE--------ENDFMTLFLAHGRLVYMFNVGHKK 130
Query: 2718 EPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTI 2777
++ + +D W+ VI R +L I D + E LP
Sbjct: 131 ------LKIRSQEKYSDGLWHDVIFIRERSSGRLVI--------DGLRVLEESLPPTEAT 176
Query: 2778 FNLDKEKSKLYVGGVPSDAKLQGI---SFPAFEGQIEELMIGDTPVGLWNFVSANKLKGA 2834
+ + K +Y+GGV ++ + S +F G + L + + A
Sbjct: 177 WKI---KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI-----------TSA 222
Query: 2835 RQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLF-----FRTYAPNG-LIYL 2888
Q + GP E G ++T G L N L F R + +G L++
Sbjct: 223 SQTFSVTPCFEGPME---TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHG 279
Query: 2889 VGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVD 2948
G + ++ M++G+V ++V+ G + V ++ DG+WH++ R L VD
Sbjct: 280 HSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVD 339
Query: 2949 NEVLKAESNSPSADIPSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISINGVNLDLSE 3004
+EV I + + GG + +L P + F GC+R I+G + S+
Sbjct: 340 SEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 398
>AL590427-5|CAH73382.1| 494|Homo sapiens netrin G1 protein.
Length = 494
Score = 140 bits (339), Expect = 9e-32
Identities = 110/378 (29%), Positives = 169/378 (44%), Gaps = 59/378 (15%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP-------CNCHNHTTECTYDPEI 306
NT GP C KC ++ + W +C P C C H+ C+Y I
Sbjct: 320 NTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY---I 376
Query: 307 DEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDP- 365
D + C++C+HNT G +C CR Y+R + D+ +VC CD
Sbjct: 377 DLLNTVI-----------CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIANVCDNE 425
Query: 366 --HFSTGNCEEESGRCEC 381
H G + RC C
Sbjct: 426 LLHCQNGGTCHNNVRCLC 443
Score = 56.0 bits (129), Expect = 2e-06
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 15/97 (15%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C+C GHS++C +NT IC++C NT G HCE C GY +A+ D +C +
Sbjct: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLD-DENVCIANV- 421
Query: 1821 YPSNNFALSCDLSENGSL----ISCNCQPGYGGARCE 1853
+N L C +NG + C C Y G CE
Sbjct: 422 --CDNELLHC---QNGGTCHNNVRCLCPAAYTGILCE 453
Score = 47.2 bits (107), Expect = 0.001
Identities = 49/186 (26%), Positives = 73/186 (39%), Gaps = 31/186 (16%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY---------YMQV-LGRERQCV 546
C C+ T + D+ C C+ GP C +C Y Y+ + G C+
Sbjct: 297 CKCNLHATV-CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
Query: 547 PC-----NCDPTGSTSTSCSADGKCN------CLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
P NC+ G S CS N C N G C+ C GY++ + +
Sbjct: 356 PSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFR--NASAQLD 412
Query: 596 DVSGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC 652
D + I + CD N L HC++ + +C C Y CE+ C+ G S +G
Sbjct: 413 DENVCIANVCD-NELLHCQNGGTCHNNVRC-LCPAA-YTGILCEKLRCEEAGSCGSDSGQ 469
Query: 653 GSVPAG 658
G+ P G
Sbjct: 470 GAPPHG 475
Score = 44.4 bits (100), Expect = 0.008
Identities = 43/179 (24%), Positives = 61/179 (34%), Gaps = 30/179 (16%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP---------------NCKP 405
C+C+ H + + CEC PDC C Y P C P
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 406 CTCNLNGTE----GEHCTPTDGL----C-PCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
++ E C+ D L C CK+N G+ CE+C GY+ + V
Sbjct: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ 515
++ VCD C C A Y C+ C+ +G+ C SGQ
Sbjct: 417 -CIANVCDNELLHCQNGGTCHNNVRCLCPAAYTGI-LCEKLRCEEAGS----CGSDSGQ 469
Score = 43.6 bits (98), Expect = 0.014
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 29/168 (17%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLH------TGDYCKP-------CNCSG 1881
+ S ++C C+ G C C Y G P + T + C P C C G
Sbjct: 309 DNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368
Query: 1882 NINPQDPGSCDSINGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFG 1936
+ N D +N C+ C +NT G C LC G++ +A + +N C A +CD
Sbjct: 369 HSNRCS--YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIANVCDN-E 425
Query: 1937 MADCDS-----TTGTCVCRPGVIGEKCD--RC-APDHWGLNTGLGCTP 1976
+ C + C+C G C+ RC G ++G G P
Sbjct: 426 LLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 473
Score = 43.2 bits (97), Expect = 0.018
Identities = 49/190 (25%), Positives = 68/190 (35%), Gaps = 46/190 (24%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H T C YD +L+ + C+HNT G +C KC+ Y RP+
Sbjct: 297 CKCNLHATVCVYD----NSKLTCE-------------CEHNTTGPDCGKCKKNYQGRPWS 339
Query: 350 K-RWDELDVCQPCQCDPHFST-GNCE--EESGRC------------ECRPEFQPPDCSSC 393
+ + C P S+ GNCE S RC C+ + C C
Sbjct: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELC 399
Query: 394 AYGYFDYPNCK-----PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
GYF + + C N+ E HC G C + C +C Y C
Sbjct: 400 RLGYFRNASAQLDDENVCIANVCDNELLHC-QNGGTC-----HNNVRC-LCPAAYTGILC 452
Query: 449 KNCECNTVGS 458
+ C GS
Sbjct: 453 EKLRCEEAGS 462
Score = 37.1 bits (82), Expect = 1.2
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 1478 CTCNRHGTTYDVCDQ-NTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFCF 1532
C C H D NT C CK N RGQ C+ C+ YF + Q D+ + C C
Sbjct: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIANVCD 423
Query: 1533 GKTTRCSS 1540
+ C +
Sbjct: 424 NELLHCQN 431
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AL513187-4|CAH73831.1| 494|Homo sapiens netrin G1 protein.
Length = 494
Score = 140 bits (339), Expect = 9e-32
Identities = 110/378 (29%), Positives = 169/378 (44%), Gaps = 59/378 (15%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKWRISQ-----NWDRFSCEP-------CNCHNHTTECTYDPEI 306
NT GP C KC ++ + W +C P C C H+ C+Y I
Sbjct: 320 NTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY---I 376
Query: 307 DEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDP- 365
D + C++C+HNT G +C CR Y+R + D+ +VC CD
Sbjct: 377 DLLNTVI-----------CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIANVCDNE 425
Query: 366 --HFSTGNCEEESGRCEC 381
H G + RC C
Sbjct: 426 LLHCQNGGTCHNNVRCLC 443
Score = 56.0 bits (129), Expect = 2e-06
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 15/97 (15%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
C+C GHS++C +NT IC++C NT G HCE C GY +A+ D +C +
Sbjct: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLD-DENVCIANV- 421
Query: 1821 YPSNNFALSCDLSENGSL----ISCNCQPGYGGARCE 1853
+N L C +NG + C C Y G CE
Sbjct: 422 --CDNELLHC---QNGGTCHNNVRCLCPAAYTGILCE 453
Score = 47.2 bits (107), Expect = 0.001
Identities = 49/186 (26%), Positives = 73/186 (39%), Gaps = 31/186 (16%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY---------YMQV-LGRERQCV 546
C C+ T + D+ C C+ GP C +C Y Y+ + G C+
Sbjct: 297 CKCNLHATV-CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
Query: 547 PC-----NCDPTGSTSTSCSADGKCN------CLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
P NC+ G S CS N C N G C+ C GY++ + +
Sbjct: 356 PSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFR--NASAQLD 412
Query: 596 DVSGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC 652
D + I + CD N L HC++ + +C C Y CE+ C+ G S +G
Sbjct: 413 DENVCIANVCD-NELLHCQNGGTCHNNVRC-LCPAA-YTGILCEKLRCEEAGSCGSDSGQ 469
Query: 653 GSVPAG 658
G+ P G
Sbjct: 470 GAPPHG 475
Score = 44.4 bits (100), Expect = 0.008
Identities = 43/179 (24%), Positives = 61/179 (34%), Gaps = 30/179 (16%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP---------------NCKP 405
C+C+ H + + CEC PDC C Y P C P
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 406 CTCNLNGTE----GEHCTPTDGL----C-PCKYNYAGKSCEICEDGYYSPECKNCECNTV 456
++ E C+ D L C CK+N G+ CE+C GY+ + V
Sbjct: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ 515
++ VCD C C A Y C+ C+ +G+ C SGQ
Sbjct: 417 -CIANVCDNELLHCQNGGTCHNNVRCLCPAAYTGI-LCEKLRCEEAGS----CGSDSGQ 469
Score = 43.6 bits (98), Expect = 0.014
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 29/168 (17%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLH------TGDYCKP-------CNCSG 1881
+ S ++C C+ G C C Y G P + T + C P C C G
Sbjct: 309 DNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368
Query: 1882 NINPQDPGSCDSINGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFG 1936
+ N D +N C+ C +NT G C LC G++ +A + +N C A +CD
Sbjct: 369 HSNRCS--YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIANVCDN-E 425
Query: 1937 MADCDS-----TTGTCVCRPGVIGEKCD--RC-APDHWGLNTGLGCTP 1976
+ C + C+C G C+ RC G ++G G P
Sbjct: 426 LLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 473
Score = 43.2 bits (97), Expect = 0.018
Identities = 49/190 (25%), Positives = 68/190 (35%), Gaps = 46/190 (24%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RPYG 349
C C+ H T C YD +L+ + C+HNT G +C KC+ Y RP+
Sbjct: 297 CKCNLHATVCVYD----NSKLTCE-------------CEHNTTGPDCGKCKKNYQGRPWS 339
Query: 350 K-RWDELDVCQPCQCDPHFST-GNCE--EESGRC------------ECRPEFQPPDCSSC 393
+ + C P S+ GNCE S RC C+ + C C
Sbjct: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELC 399
Query: 394 AYGYFDYPNCK-----PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
GYF + + C N+ E HC G C + C +C Y C
Sbjct: 400 RLGYFRNASAQLDDENVCIANVCDNELLHC-QNGGTC-----HNNVRC-LCPAAYTGILC 452
Query: 449 KNCECNTVGS 458
+ C GS
Sbjct: 453 EKLRCEEAGS 462
Score = 37.1 bits (82), Expect = 1.2
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 1478 CTCNRHGTTYDVCDQ-NTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFCF 1532
C C H D NT C CK N RGQ C+ C+ YF + Q D+ + C C
Sbjct: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIANVCD 423
Query: 1533 GKTTRCSS 1540
+ C +
Sbjct: 424 NELLHCQN 431
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AB011542-1|BAA32470.1| 375|Homo sapiens MEGF9 protein.
Length = 375
Score = 137 bits (331), Expect = 8e-31
Identities = 63/188 (33%), Positives = 93/188 (49%), Gaps = 16/188 (8%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+CQC G C++C +G+Y C+PCQCN S CD TG CLNC +N+ G+HCE
Sbjct: 44 KCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCE 103
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCN-CQPGYGGARCE 1853
C G++ + ++CL C C + SC + + C+ C+ GY G C
Sbjct: 104 ECKEGFY--QSPDATKECLRCPCSAVTSTG----SCSIKSSELEPECDQCKDGYIGPNCN 157
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP-QDPGSCDSINGDCLKCVNNTAGAACNL 1912
C GYY C+ C C G+++P + P C +G+C+ C++NT G C
Sbjct: 158 KCENGYYNF--------DSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCEN 209
Query: 1913 CAPGFYGD 1920
C G+ D
Sbjct: 210 CLEGYVHD 217
Score = 136 bits (328), Expect = 2e-30
Identities = 79/226 (34%), Positives = 106/226 (46%), Gaps = 27/226 (11%)
Query: 333 EGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS 392
+G++C C+ +Y Y +CQPC C PH + SG+C+C+ C
Sbjct: 4 QGLHCETCKEGFYLNYTS-----GLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDR 58
Query: 393 CAYGYFDYP--NCKPCTCNLNGTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYY-SP-- 446
C GY+ + C PC CN C G C C+ N G CE C++G+Y SP
Sbjct: 59 CQDGYYGFSKNGCLPCQCN---NRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPDA 115
Query: 447 --ECKNCECNTV---GSVSYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYNYPT-CKPCNC 499
EC C C+ V GS S +L +C CK Y G CN+C+ GYYN+ + C+ C C
Sbjct: 116 TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQC 175
Query: 500 ----DTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYMQVLG 540
D T P IC SG+CI C G C+ CL GY + G
Sbjct: 176 HGHVDPVKT-PKICKPESGECINCLHNTTGFWCENCLEGYVHDLEG 220
Score = 132 bits (320), Expect = 2e-29
Identities = 74/223 (33%), Positives = 109/223 (48%), Gaps = 21/223 (9%)
Query: 521 GFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
G+ G C+ C G+Y+ C PC+C P G+ S C++ GKC C G+ CD+C
Sbjct: 2 GYQGLHCETCKEGFYLNYTSG--LCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRC 59
Query: 581 SPGYYKYP--DCLSCNCDVSGSIGSTCDD-NGLC-HCKSNFDGAKCDTCREQFYNYP-AC 635
GYY + CL C C+ + ++CD G C +C+ N G C+ C+E FY P A
Sbjct: 60 QDGYYGFSKNGCLPCQCN---NRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPDAT 116
Query: 636 EECNCDPRGVTASFAGCGSVPAGEL---C-QCKDRVQGRICNDCKPLYWNLQEYNPFGCE 691
+EC P S C S+ + EL C QCKD G CN C+ Y+N C
Sbjct: 117 KECLRCPCSAVTSTGSC-SIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI----CR 171
Query: 692 QCNCN-LAGTLNSLGACNTKSGQCV-CKQHVGERQCDQCLDGF 732
+C C+ + + C +SG+C+ C + C+ CL+G+
Sbjct: 172 KCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 214
Score = 118 bits (285), Expect = 3e-25
Identities = 69/217 (31%), Positives = 105/217 (48%), Gaps = 23/217 (10%)
Query: 431 YAGKSCEICEDGYY----SPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQA 486
Y G CE C++G+Y S C+ C+C+ G++S C+ +G C CK G C++CQ
Sbjct: 3 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRCQD 61
Query: 487 GYYNYPT--CKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYMQVLGRER 543
GYY + C PC C+ CD ++G C+ C+ G C++C G+Y Q +
Sbjct: 62 GYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEECKEGFY-QSPDATK 117
Query: 544 QCVPCNCD---PTGSTS-TSCSADGKCN-CLTNFGGAQCDQCSPGYYKYPD-CLSCNCDV 597
+C+ C C TGS S S + +C+ C + G C++C GYY + C C C
Sbjct: 118 ECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHG 177
Query: 598 SGSIGST---C-DDNGLC-HCKSNFDGAKCDTCREQF 629
T C ++G C +C N G C+ C E +
Sbjct: 178 HVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 214
Score = 114 bits (275), Expect = 5e-24
Identities = 70/222 (31%), Positives = 103/222 (46%), Gaps = 16/222 (7%)
Query: 1316 PNETGL-CREAMFSITSEYNSG-ARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
P GL C Y SG +PC C G+ + CN+ G+C CK VIG C C
Sbjct: 1 PGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRC 59
Query: 1374 RTGYYGFP--NCRPCHCPS-TAICDD-NGMCI-CPKNVEGENCDRCKPYTFNF-DVQRGC 1427
+ GYYGF C PC C + +A CD G C+ C +N +G +C+ CK + D + C
Sbjct: 60 QDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKEC 119
Query: 1428 DDCNCNPLGVVGN-QLQCEADSGKC-ACRENVRGRVCDHCVPGHYAFPD-CYQCTCNRH- 1483
C C+ + G+ ++ +C C++ G C+ C G+Y F C +C C+ H
Sbjct: 120 LRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHV 179
Query: 1484 --GTTYDVCDQNTAQCY-CKTNVRGQACDTCKEEYFNLQDDN 1522
T +C + +C C N G C+ C E Y + + N
Sbjct: 180 DPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGN 221
Score = 104 bits (250), Expect = 5e-21
Identities = 69/243 (28%), Positives = 102/243 (41%), Gaps = 36/243 (14%)
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
G HCE C G++ + T G C C C S + ALS + +G C C+ G G
Sbjct: 5 GLHCETCKEGFYLNYTSGL---CQPCDC-----SPHGALSIPCNSSGK---CQCKVGVIG 53
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
+ C+ C GYYG ++ C PC C+ SCD++ G CL C N+ G
Sbjct: 54 SICDRCQDGYYGFSKNG-------CLPCQCNNR-----SASCDALTGACLNCQENSKGNH 101
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEF-GMADCDSTTG----TC-VCRPGVIGEKCDRCAP 1963
C C GFY +K C C C C + C C+ G IG C++C
Sbjct: 102 CEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCEN 161
Query: 1964 DHWGLNTGLGCTPCNCGIASESTQ----CDDDNGQC-RCAKGVTGKQCDQCAAGFWNYTK 2018
++ ++ C C C + + C ++G+C C TG C+ C G+ + +
Sbjct: 162 GYYNFDS--ICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLE 219
Query: 2019 DGC 2021
C
Sbjct: 220 GNC 222
Score = 103 bits (248), Expect = 9e-21
Identities = 78/236 (33%), Positives = 97/236 (41%), Gaps = 44/236 (18%)
Query: 1742 YRGLSCEQCAEGHY-RLPSGFCVPCQCNGH---SDQCDVNTGICLNCADNTIGDHCEFCM 1797
Y+GL CE C EG Y SG C PC C+ H S C+ ++G C C IG C+ C
Sbjct: 3 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCN-SSGKC-QCKVGVIGSICDRCQ 60
Query: 1798 SGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAA 1857
GY+G + G CL C C NN + SCD L NCQ G CE C
Sbjct: 61 DGYYGFSKNG----CLPCQC------NNRSASCDALTGACL---NCQENSKGNHCEECKE 107
Query: 1858 GYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC----DSINGDCLKCVNNTAGAACNLC 1913
G+Y P+ T C C CS GSC + +C +C + G CN C
Sbjct: 108 GFYQSPDAT-----KECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKC 159
Query: 1914 APGFYGDAIFSKNCTACICDEFGMAD-------CDSTTGTCV-CRPGVIGEKCDRC 1961
G+Y F C C C G D C +G C+ C G C+ C
Sbjct: 160 ENGYYN---FDSICRKCQC--HGHVDPVKTPKICKPESGECINCLHNTTGFWCENC 210
Score = 102 bits (245), Expect = 2e-20
Identities = 70/239 (29%), Positives = 107/239 (44%), Gaps = 28/239 (11%)
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNN 1904
PGY G CE C G+Y +T C+PC+CS + P C+S +G C +C
Sbjct: 1 PGYQGLHCETCKEGFY------LNYTSGLCQPCDCSPHGALSIP--CNS-SGKC-QCKVG 50
Query: 1905 TAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCA 1962
G+ C+ C G+YG FSKN C C C+ A CD+ TG C+ C+ G C+ C
Sbjct: 51 VIGSICDRCQDGYYG---FSKNGCLPCQCNN-RSASCDALTGACLNCQENSKGNHCEECK 106
Query: 1963 PDHW-GLNTGLGCTPCNCGIASESTQCDDDNG----QC-RCAKGVTGKQCDQCAAGFWNY 2016
+ + C C C + + C + +C +C G G C++C G++N+
Sbjct: 107 EGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNF 166
Query: 2017 TKDGCDHCNCN---TGYSVGFMCN-ATGQC-ECLPGVIGEKCDRCPERWVLIPQEGCLE 2070
C C C+ +C +G+C CL G C+ C E +V + C++
Sbjct: 167 DSI-CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCIK 224
Score = 91.5 bits (217), Expect = 5e-17
Identities = 64/231 (27%), Positives = 100/231 (43%), Gaps = 45/231 (19%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C+ H P + +G C+C+ G C++C G+ + S+N C P
Sbjct: 27 CDCSPHGALSIPCNSSGK-----CQCKVGVIGSICDRCQDGY----YGFSKN----GCLP 73
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C+N + C +L G CLNCQ N++G +C +C+ +Y+
Sbjct: 74 CQCNNRSASCD----------ALT--------GACLNCQENSKGNHCEECKEGFYQSP-- 113
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCE-----CRPEFQPPDCSSCAYGYFDYPN-CK 404
D C C C STG+C +S E C+ + P+C+ C GY+++ + C+
Sbjct: 114 --DATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICR 171
Query: 405 PCTCNLN---GTEGEHCTPTDGLC-PCKYNYAGKSCEICEDGYYSPECKNC 451
C C+ + + C P G C C +N G CE C +GY NC
Sbjct: 172 KCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNC 222
Score = 83.4 bits (197), Expect = 1e-14
Identities = 67/242 (27%), Positives = 101/242 (41%), Gaps = 47/242 (19%)
Query: 262 GPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEG 321
G C C GF N+ C+PC+C H LS+ N
Sbjct: 5 GLHCETCKEGFYL-------NYTSGLCQPCDCSPHGA------------LSIPCN----S 41
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC-E 380
GKC C+ G C++C+ YY + K + C PCQC+ + +C+ +G C
Sbjct: 42 SGKC-QCKVGVIGSICDRCQDGYY-GFSK-----NGCLPCQCNNR--SASCDALTGACLN 92
Query: 381 CRPEFQPPDCSSCAYGYFDYPN----CKPCTCNLNGTEGEHCTPTDGLCP----CKYNYA 432
C+ + C C G++ P+ C C C+ + G + L P CK Y
Sbjct: 93 CQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYI 152
Query: 433 GKSCEICEDGYYSPE--CKNCECN-TVGSVS--YVCDKLTGDC-TCKSKYSGRTCNQCQA 486
G +C CE+GYY+ + C+ C+C+ V V +C +G+C C +G C C
Sbjct: 153 GPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLE 212
Query: 487 GY 488
GY
Sbjct: 213 GY 214
Score = 82.6 bits (195), Expect = 2e-14
Identities = 52/166 (31%), Positives = 80/166 (48%), Gaps = 26/166 (15%)
Query: 617 FDGAKCDTCREQFY-NYPA--CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN 673
+ G C+TC+E FY NY + C+ C+C P G + C S +G+ CQCK V G IC+
Sbjct: 3 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS--IPCNS--SGK-CQCKVGVIGSICD 57
Query: 674 DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGERQCDQCLDGF 732
C+ Y+ ++ GC C CN N +C+ +G C+ C+++ C++C +GF
Sbjct: 58 RCQDGYYG---FSKNGCLPCQCN-----NRSASCDALTGACLNCQENSKGNHCEECKEGF 109
Query: 733 YRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
Y+ + C C C + +TG C S CDQ
Sbjct: 110 YQ-SPDATKECLRCPC--------SAVTSTGSCSIKSSELEPECDQ 146
Score = 75.8 bits (178), Expect = 3e-12
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 7/125 (5%)
Query: 1951 PGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
PG G C+ C + T C PC+C + + +G+C+C GV G CD+C
Sbjct: 1 PGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQ 60
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQC-ECLPGVIGEKCDRCPERWVLIPQ--E 2066
G++ ++K+GC C CN + C+A TG C C G C+ C E + P +
Sbjct: 61 DGYYGFSKNGCLPCQCNNRSA---SCDALTGACLNCQENSKGNHCEECKEGFYQSPDATK 117
Query: 2067 GCLEC 2071
CL C
Sbjct: 118 ECLRC 122
Score = 51.2 bits (117), Expect = 7e-05
Identities = 34/115 (29%), Positives = 45/115 (39%), Gaps = 21/115 (18%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
RC C+ T + + L +C+ GP CNKC +G+ N+D C
Sbjct: 121 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY--------YNFDSI-CR 171
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C CH H DP K + G+C+NC HNT G C C Y
Sbjct: 172 KCQCHGHV-----DPVKTPKICKPE-------SGECINCLHNTTGFWCENCLEGY 214
Score = 42.7 bits (96), Expect = 0.024
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 725 CDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHY 784
C+ C +GFY T+ + C CDC G++ C+ ++G+C C V G CD+ +Y
Sbjct: 8 CETCKEGFYLNYTSGL--CQPCDCSPHGALSIPCN-SSGKCQCKVGVIGSICDRCQDGYY 64
>M59832-1|AAA63215.1| 1130|Homo sapiens merosin protein.
Length = 1130
Score = 132 bits (319), Expect = 2e-29
Identities = 150/650 (23%), Positives = 270/650 (41%), Gaps = 78/650 (12%)
Query: 2619 LQKLKDLVEQARTVANRIQVGVTF--DRWSTLQPRLPDTVDEMSTSTHVSAYFRTKEKDG 2676
+ ++K+L+ QAR AN I+V V+ D T +P + + + ++ +T D
Sbjct: 147 ISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEI-----KKGSYNNIVVNVKTAVADN 201
Query: 2677 FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNR 2736
+ YLG+ K D++ I ++ G + D+G + P D + D+
Sbjct: 202 LLFYLGSAKFI--------DFLAIEMRKGKVSFLWDVGSGVGRVEYP-----DLTIDDSY 248
Query: 2737 WYQVIVDRLGRRVKLSIRESLDNGTDTI--HSKEADLPGHHTIFNLDKEKSKLYVGGVPS 2794
WY+++ R GR +S+R +LD +I + + P +TI ++D + L+VGG+
Sbjct: 249 WYRIVASRTGRNGTISVR-ALDGPKASIVPSTHHSTSPPGYTILDVDAN-AMLFVGGLTG 306
Query: 2795 DAK-LQGISFPAFEGQIEELMIGDTPVGLWNF-VSANKLKGARQRDKLISSQSGPQEYRF 2852
K + F G + E + P+GLWNF KG ++ S+ Q F
Sbjct: 307 KLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQ---F 363
Query: 2853 DGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLI-YLVGEG-GYFFSLLMQDGRVYLQVS 2910
DG GYA ++ P + V+ FRT++ + L+ YL F S+ + DG + +
Sbjct: 364 DGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYD 423
Query: 2911 LGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTV--------DNEVLKAESNSPSAD 2962
LG+ + V + + +NDGKW R + ++++ +N + N+ D
Sbjct: 424 LGS--GMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLD 481
Query: 2963 IPSLDTMNFGG----NNKGILQVPD---RGFDGCMRQISINGVNLDLSENLESIGMAYGC 3015
+ + D + FGG N + P+ + + GC++ I I+ ++ + + +G+ GC
Sbjct: 482 LKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGC 541
Query: 3016 QFASL--VSFNGTDSYLRFVDVTSE-NPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSIS 3072
++ VSF ++ V + ++ L F T +G+ + + T P
Sbjct: 542 SLENVYTVSF-PKPGFVELSPVPIDVGTEINLSFSTKNESGI--ILLGSGGTPAPPRRKR 598
Query: 3073 LSLVNGKLVVVSQREQLDTGLNT----------------YNDSQWHVLTVTHNTSALKLV 3116
V++ R +L+ L+T ++D + + V +
Sbjct: 599 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGRERSVHVERTRGIFTVQ 658
Query: 3117 VDD-FDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLN 3175
VD+ Y T P+ + LF+GG P + S L + PF GCI + IN ++
Sbjct: 659 VDENRRYMQNLTVEQPIEVKK--LFVGGAPPEFQPS-PLRNIPPFEGCIWNLVINSVPMD 715
Query: 3176 LLEPFSNNSVTFGRCG----TTITTGGVNPDKVTWSIPTSPDVLPMPEPV 3221
P S + GRC G + V P P P PV
Sbjct: 716 FARPVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPV 765
Score = 111 bits (268), Expect = 3e-23
Identities = 93/358 (25%), Positives = 158/358 (44%), Gaps = 23/358 (6%)
Query: 3291 CALAYDPHYSLGDPNEGYRFGSRNVSRIEYAKLPGRQLEGFDLTISFRTFDKQGGVIFYA 3350
CA +P +G G S + K+ R + + RT + + G++FY
Sbjct: 771 CAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNR----LTIELEVRT-EAESGLLFYM 825
Query: 3351 ESAHDKNPVQFLAFFMRDAKLHYMFNCG-GETGVISSTHTYNDIDWHTVTLTRNGGHGKL 3409
N F +R+ ++ ++ G G+T + T ND WH + + R+ G L
Sbjct: 826 ARI---NHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKI-NDGQWHKIKIMRSKQEGIL 881
Query: 3410 AVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ- 3468
VD S L + Y GGL +N +I Y GC++ L M
Sbjct: 882 YVDGASNRTISPKKADILDVVGMLYVGGLP-INYTTRRIGPVTYS-IDGCVRNLHMAEAP 939
Query: 3469 -QVTRIGNAVNALRCVDNIEDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTT 3527
+ + ++ + C N + G YF+ + + K + FKVG ++ + E R TT
Sbjct: 940 ADLEQPTSSFHVGTCFANAQRGTYFDGTG-----FAKAVGGFKVGLDLLVEFEFRTTTTT 994
Query: 3528 GLLLSVHGKK-DYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXX 3586
G+LL + +K D M +E++D +++ +V+NG G F A Y +LCDG WHK+
Sbjct: 995 GVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIK 1054
Query: 3587 XXXXXXXDGH--FSKPGIGAYTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
DG+ ++ A TS DT+ +++GG + K G+ + F GC+R++
Sbjct: 1055 HRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDL-KQFGLTTSIPFRGCIRSL 1111
Score = 59.3 bits (137), Expect = 3e-07
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 44/335 (13%)
Query: 2670 RTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSID 2729
RT+ + G + Y+ R D+ + ++NG PY D+G P +++
Sbjct: 814 RTEAESGLLFYMA--------RINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKIN-- 863
Query: 2730 KMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYV 2789
D +W+++ + R + L + + + TI K+AD+ LD LYV
Sbjct: 864 ----DGQWHKIKIMRSKQEGILYVDGASNR---TISPKKADI--------LDVV-GMLYV 907
Query: 2790 GGVPSDAKLQGISFPAF--EGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGP 2847
GG+P + + I + +G + L + + P L S+ + ++Q G
Sbjct: 908 GGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTC-----FANAQRGT 962
Query: 2848 QEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGE---GGYFFSLLMQDGR 2904
FDG G+A G G+ V FRT G++ + G ++ +
Sbjct: 963 Y---FDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 1018
Query: 2905 VYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSP-SADI 2963
++ G + G DG+WHK+ A + + LTVD ++A+S +P S
Sbjct: 1019 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA 1078
Query: 2964 PSLDTMNFGGNNKGILQ---VPDRGFDGCMRQISI 2995
+ D + GG + Q F GC+R + +
Sbjct: 1079 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKL 1113
Score = 49.2 bits (112), Expect = 3e-04
Identities = 70/307 (22%), Positives = 125/307 (40%), Gaps = 32/307 (10%)
Query: 2878 RTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLD 2935
RT A +GL++ + + F ++ +++G Y LG+ + ++ T NDG+WHK+
Sbjct: 814 RTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIK 871
Query: 2936 ARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG-----NNKGILQVPDRGFDGCM 2990
R + L VD + S + + + + GG + I V DGC+
Sbjct: 872 IMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVT-YSIDGCV 930
Query: 2991 RQISINGVNLDLSENLESIGMAYGCQFASL---VSFNGTDSYLRFVDVTSENPQLTLKF- 3046
R + + DL + S + G FA+ F+GT + + V L ++F
Sbjct: 931 RNLHMAEAPADLEQPTSSFHV--GTCFANAQRGTYFDGT-GFAKAVGGFKVGLDLLVEFE 987
Query: 3047 -KTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQ------LDTGLNTYN-D 3098
+T G+L S+ D + + +++ KL+ D G+ + D
Sbjct: 988 FRTTTTTGVLLGISSQKM-----DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCD 1042
Query: 3099 SQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSLGSK 3157
QWH +T ++L VD + P + +F+GG P + L +
Sbjct: 1043 GQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGF-PDDLKQFGLTTS 1101
Query: 3158 VPFTGCI 3164
+PF GCI
Sbjct: 1102 IPFRGCI 1108
Score = 40.3 bits (90), Expect = 0.13
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 3346 VIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH-TYNDIDWHTVTLTRNG 3404
++FY SA + FLA MR K+ ++++ G G + T +D W+ + +R G
Sbjct: 202 LLFYLGSAKF---IDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTG 258
Query: 3405 GHGKLAVDSEMVGETSVTCNTPLSLAPPYY 3434
+G ++V + + S+ +T S +PP Y
Sbjct: 259 RNGTISVRALDGPKASIVPSTHHSTSPPGY 288
Score = 39.5 bits (88), Expect = 0.22
Identities = 42/177 (23%), Positives = 65/177 (36%), Gaps = 11/177 (6%)
Query: 3492 FEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVH--GKKDYMVLELLDSEV 3549
F S N+H ++ KV + ++I +EVR +GLL + D+ ++L +
Sbjct: 786 FGLSRNSHIAIA--FDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 843
Query: 3550 VANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTST- 3608
+ + G+G + DG WHKI DG ++
Sbjct: 844 YFSYDLGSGDTHTMIPTK----INDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 899
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVC 3665
D LY+GG R GCVRN+ + E P + HVG C
Sbjct: 900 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT--SSFHVGTC 954
>X84392-1|CAA59114.1| 158|Homo sapiens alpha3A protein.
Length = 158
Score = 129 bits (312), Expect = 2e-28
Identities = 59/118 (50%), Positives = 77/118 (65%), Gaps = 12/118 (10%)
Query: 1750 CAEGHYR----LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDAT 1805
C+ G+YR L +G CVPC CNGHS+QC +GIC+NC NT G+HCE C GY+G+A
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 107
Query: 1806 VGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP 1863
G+ R ACP P+ +N+FA C + NG + C+C+ GY G +CE CA GY GIP
Sbjct: 108 HGSCR-----ACPCPH-TNSFATGCVV--NGGDVRCSCKAGYTGTQCERCAPGYLGIP 157
Score = 84.2 bits (199), Expect = 8e-15
Identities = 44/118 (37%), Positives = 61/118 (51%), Gaps = 13/118 (11%)
Query: 1855 CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCA 1914
C+ GYY + L+TG C PCNC+G+ N C +G C+ C +NTAG C C
Sbjct: 48 CSPGYYR--DHKGLYTGR-CVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQ 99
Query: 1915 PGFYGDAIFSKNCTACICDEFG--MADCDSTTG--TCVCRPGVIGEKCDRCAPDHWGL 1968
G+YG+A+ +C AC C C G C C+ G G +C+RCAP + G+
Sbjct: 100 EGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYLGI 156
Score = 79.0 bits (186), Expect = 3e-13
Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 15/120 (12%)
Query: 479 RTCNQCQAGYYN-----YP-TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCL 531
R C GYY Y C PCNC+ + C D SG C+ C+ G C++C
Sbjct: 43 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHCERCQ 99
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG---KCNCLTNFGGAQCDQCSPGYYKYP 588
GYY + C C C T S +T C +G +C+C + G QC++C+PGY P
Sbjct: 100 EGYYGNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYLGIP 157
Score = 74.9 bits (176), Expect = 5e-12
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 18/122 (14%)
Query: 384 EFQPPDCSSCAYGYF-DYPN-----CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSC 436
EF+P C+ GY+ D+ C PC CN + + C G+C C++N AG+ C
Sbjct: 41 EFRPSQ--GCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHC 95
Query: 437 EICEDGYYS----PECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQAGYYN 490
E C++GYY C+ C C S + C GD C+CK+ Y+G C +C GY
Sbjct: 96 ERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYLG 155
Query: 491 YP 492
P
Sbjct: 156 IP 157
Score = 72.5 bits (170), Expect = 3e-11
Identities = 38/107 (35%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 1964 DHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGVTGKQCDQCAAGFW-NYTKDGC 2021
DH GL TG C PCNC S QC D +G C C G+ C++C G++ N C
Sbjct: 55 DHKGLYTGR-CVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSC 111
Query: 2022 DHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCDRCPERWVLIPQ 2065
C C S C G +C C G G +C+RC ++ IP+
Sbjct: 112 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYLGIPR 158
Score = 71.3 bits (167), Expect = 6e-11
Identities = 42/129 (32%), Positives = 59/129 (45%), Gaps = 11/129 (8%)
Query: 514 GQCICKAGFGGPRCDQ-CLSGYYMQVLGRER-QCVPCNCDPTGSTSTSCSADGKC-NCLT 570
GQ +A + R Q C GYY G +CVPCNC+ G ++ G C NC
Sbjct: 31 GQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQH 88
Query: 571 NFGGAQCDQCSPGYYK---YPDCLSCNCDVSGSIGSTCDDNG---LCHCKSNFDGAKCDT 624
N G C++C GYY + C +C C + S + C NG C CK+ + G +C+
Sbjct: 89 NTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 148
Query: 625 CREQFYNYP 633
C + P
Sbjct: 149 CAPGYLGIP 157
Score = 71.3 bits (167), Expect = 6e-11
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 7/107 (6%)
Query: 1913 CAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWGLN 1969
C+PG+Y D +++ C C C+ C +G CV C+ GE C+RC ++G
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 106
Query: 1970 TGLGCTPCNCGIASE-STQCDDDNG--QCRCAKGVTGKQCDQCAAGF 2013
C C C + +T C + G +C C G TG QC++CA G+
Sbjct: 107 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 153
Score = 66.5 bits (155), Expect = 2e-09
Identities = 41/119 (34%), Positives = 53/119 (44%), Gaps = 30/119 (25%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PCNC+ H+ +C +G G C+NCQHNT G +C +C+ Y
Sbjct: 64 CVPCNCNGHSNQCQ------------------DGSGICVNCQHNTAGEHCERCQEGY--- 102
Query: 348 YGKRWDELDVCQPCQCDPH---FSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYP 401
YG C+ C C PH F+TG C G RC C+ + C CA GY P
Sbjct: 103 YGNAVH--GSCRACPC-PHTNSFATG-CVVNGGDVRCSCKAGYTGTQCERCAPGYLGIP 157
Score = 63.3 bits (147), Expect = 2e-08
Identities = 40/109 (36%), Positives = 52/109 (47%), Gaps = 12/109 (11%)
Query: 580 CSPGYYK-----YPD-CLSCNCDVSGSIGSTCDDNGLC-HCKSNFDGAKCDTCREQFYNY 632
CSPGYY+ Y C+ CNC+ G D +G+C +C+ N G C+ C+E +Y
Sbjct: 48 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 105
Query: 633 PACEECNCDPRGVTASFA-GCGSVPAGEL-CQCKDRVQGRICNDCKPLY 679
C P T SFA GC V G++ C CK G C C P Y
Sbjct: 106 AVHGSCRACPCPHTNSFATGC-VVNGGDVRCSCKAGYTGTQCERCAPGY 153
Score = 62.5 bits (145), Expect = 3e-08
Identities = 33/115 (28%), Positives = 46/115 (40%), Gaps = 9/115 (7%)
Query: 1368 RTCSACRTGYY----GF--PNCRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYT 1418
R C GYY G C PC+C S D +G+C+ C N GE+C+RC+
Sbjct: 43 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGY 102
Query: 1419 FNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFP 1473
+ V C C C +C+C+ G C+ C PG+ P
Sbjct: 103 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYLGIP 157
Score = 50.4 bits (115), Expect = 1e-04
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 13/128 (10%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG-CEQCNCNLAGTLNSLGACNTKSGQC 714
P G+ V+ R C P Y+ + G C CNCN G N C SG C
Sbjct: 29 PPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ---CQDGSGIC 83
Query: 715 V-CKQHVGERQCDQCLDGFYRLQTNDVFG-CTECDCDIGGSIDNNCDKTTG--QCHCHSR 770
V C+ + C++C +G+Y N V G C C C S C G +C C +
Sbjct: 84 VNCQHNTAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 140
Query: 771 VEGRRCDQ 778
G +C++
Sbjct: 141 YTGTQCER 148
Score = 46.0 bits (104), Expect = 0.003
Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 27/114 (23%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNGH++ C+ D +G + CQHNT G C +C G+ N SC
Sbjct: 67 CNCNGHSNQCQ--DGSG----ICVNCQHNTAGEHCERCQEGY-------YGNAVHGSCRA 113
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C C P + +NG G +C +C+ G C +C P Y
Sbjct: 114 CPC----------PHTNSFATGCVVNG---GDVRC-SCKAGYTGTQCERCAPGY 153
Score = 43.6 bits (98), Expect = 0.014
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 5/70 (7%)
Query: 1738 CPRAYRGLSCEQCAEGHY-RLPSGFCVPCQC---NGHSDQCDVNTG-ICLNCADNTIGDH 1792
C G CE+C EG+Y G C C C N + C VN G + +C G
Sbjct: 86 CQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQ 145
Query: 1793 CEFCMSGYHG 1802
CE C GY G
Sbjct: 146 CERCAPGYLG 155
Score = 38.3 bits (85), Expect = 0.52
Identities = 20/77 (25%), Positives = 28/77 (36%), Gaps = 4/77 (5%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGG--QCPCKPN 1364
C + + + C+E + + + R C C S C GG +C CK
Sbjct: 83 CVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 140
Query: 1365 VIGRTCSACRTGYYGFP 1381
G C C GY G P
Sbjct: 141 YTGTQCERCAPGYLGIP 157
Score = 36.3 bits (80), Expect = 2.1
Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 12/82 (14%)
Query: 1457 VRGRVCDHCVPGHYAFPD------CYQCTCNRHGTTYDVCDQNTAQCY-CKTNVRGQACD 1509
V R C PG+Y C C CN H C + C C+ N G+ C+
Sbjct: 40 VEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNTAGEHCE 96
Query: 1510 TCKEEYFNLQDDNPDGCTKCFC 1531
C+E Y+ + C C C
Sbjct: 97 RCQEGYYG--NAVHGSCRACPC 116
Score = 34.3 bits (75), Expect = 8.4
Identities = 23/98 (23%), Positives = 36/98 (36%), Gaps = 8/98 (8%)
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCN 694
C CNC+ ++ GS G C+ G C C+ Y+ + C C
Sbjct: 64 CVPCNCNGH---SNQCQDGS---GICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACP 115
Query: 695 CNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGF 732
C + + N +C CK QC++C G+
Sbjct: 116 CPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 153
>BC062318-1|AAH62318.1| 559|Homo sapiens LAMA1 protein protein.
Length = 559
Score = 124 bits (299), Expect = 6e-27
Identities = 91/321 (28%), Positives = 152/321 (47%), Gaps = 19/321 (5%)
Query: 3335 ISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYNDID 3394
+S RTF G+I+Y AH +N + + +LH+MF+ G +S +D
Sbjct: 225 LSIRTF-ASSGLIYYM--AH-QNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGK 280
Query: 3395 WHTVTLTRNGGHGKLAVDS-EMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFY 3453
WHTV G + VD E T V T L + +Y GGL ++ ++ N
Sbjct: 281 WHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLP--SQYQARKIGNIT 338
Query: 3454 QPFMGCLKGLLMNGQQVTRIG--NAVNALRCVDNIEDGVYFEASNNTHSNYLKLL-ENFK 3510
C+ + +N +Q+ + +A RC ++G YF+ S Y L+ E +K
Sbjct: 339 HSIPACIGDVTVNSKQLDKDSPVSAFTVNRCYAVAQEGTYFDGSG-----YAALVKEGYK 393
Query: 3511 VGDEVSISMEVRPRNTTGLLLSVH-GKKDYMVLELLDSEVVANVENGNGPFRATYKLSNK 3569
V +V+I++E R + G+LL + K D + LEL+D +V+ +V NG G A Y+
Sbjct: 394 VQSDVNITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTA 453
Query: 3570 HYLCDGNWHKIHXXXXXXXXXXXXDGHF--SKPGIGAYTSTDTHSALYIGGHERPIHKVR 3627
LCDG WH + DG+ ++ TS DT++ +Y+GG+ + K +
Sbjct: 454 TVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGV-KQK 512
Query: 3628 GVHSRRGFTGCVRNIVVGETP 3648
+ S+ F GC+R + + ++P
Sbjct: 513 CLRSQTSFRGCLRKLALIKSP 533
Score = 71.3 bits (167), Expect = 6e-11
Identities = 76/309 (24%), Positives = 123/309 (39%), Gaps = 34/309 (11%)
Query: 2696 DYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRE 2755
DY V+ + G + + D+G PA +++D +W+ V D + R+ +++
Sbjct: 246 DYAVLQLHGGRLHFMFDLGKGRTKVSHPA------LLSDGKWHTVKTDYVKRKGFITV-- 297
Query: 2756 SLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVPSDAKLQGISFPAFEGQIEELMI 2815
D S + G T+ +++ Y+GG+PS + + I I
Sbjct: 298 ------DGRESPMVTVVGDGTMLDVE---GLFYLGGLPSQYQARKIGNITHS---IPACI 345
Query: 2816 GDTPVGLWNFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLL 2875
GD V + + +Q G FDG GYA + GY + L
Sbjct: 346 GDVTVNSKQLDKDSPVSAFTVNRCYAVAQEGTY---FDGSGYAALVKEGYKVQSDVNITL 402
Query: 2876 FFRTYAPNGLIYLVGEGGY-FFSLLMQDGRVYLQVS--LGNTEDLIIVGTTRAYNDGKWH 2932
FRT + NG++ + L + DG+V V+ G T DGKWH
Sbjct: 403 EFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWH 462
Query: 2933 KLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMN---FGGNNKGILQV---PDRGF 2986
L A + + +L VD + AE SP S+DT N GG G+ Q F
Sbjct: 463 TLQANKSKHRITLIVDGNAVGAE--SPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSF 520
Query: 2987 DGCMRQISI 2995
GC+R++++
Sbjct: 521 RGCLRKLAL 529
Score = 51.6 bits (118), Expect = 5e-05
Identities = 66/310 (21%), Positives = 122/310 (39%), Gaps = 26/310 (8%)
Query: 2873 VLLFFRTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGK 2930
V L RT+A +GLIY + + L + GR++ LG V +DGK
Sbjct: 223 VELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTK--VSHPALLSDGK 280
Query: 2931 WHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDRG----- 2985
WH + K +TVD + + ++ + + G Q G
Sbjct: 281 WHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHS 340
Query: 2986 FDGCMRQISINGVNLDLSENLES--IGMAYG-CQFASLVSFNGTDSYLRFVDVTSENPQL 3042
C+ +++N LD + + + Y Q + +G + ++ + +
Sbjct: 341 IPACIGDVTVNSKQLDKDSPVSAFTVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNI 400
Query: 3043 TLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLV--VVSQREQLDTGLNTYN--- 3097
TL+F+T+ NG+L + +S + D+I L LV+GK++ V + ++
Sbjct: 401 TLEFRTSSQNGVL-LGISTAKV----DAIGLELVDGKVLFHVNNGAGRITAAYEPKTATV 455
Query: 3098 --DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSL 3154
D +WH L + + L+VD + + + +++GG P V L
Sbjct: 456 LCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGG-YPAGVKQKCL 514
Query: 3155 GSKVPFTGCI 3164
S+ F GC+
Sbjct: 515 RSQTSFRGCL 524
Score = 34.3 bits (75), Expect = 8.4
Identities = 35/153 (22%), Positives = 65/153 (42%), Gaps = 14/153 (9%)
Query: 3044 LKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN---TYNDSQ 3100
L +T +GL++ + Q D L L G+L + + T ++ +D +
Sbjct: 225 LSIRTFASSGLIYYMAHQNQA----DYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGK 280
Query: 3101 WHVLTVTHNTSALKLVVDDFDY-FSTDTAPPPLHILDGVLFIGGVQPGYVVS--GSLGSK 3157
WH + + + VD + T + ++G+ ++GG+ Y G++
Sbjct: 281 WHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHS 340
Query: 3158 VPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
+P CIGD T+N + L+ P S + T RC
Sbjct: 341 IP--ACIGDVTVNSKQLDKDSPVS--AFTVNRC 369
>BC039051-1|AAH39051.1| 747|Homo sapiens LAMA1 protein protein.
Length = 747
Score = 124 bits (299), Expect = 6e-27
Identities = 91/321 (28%), Positives = 152/321 (47%), Gaps = 19/321 (5%)
Query: 3335 ISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYNDID 3394
+S RTF G+I+Y AH +N + + +LH+MF+ G +S +D
Sbjct: 413 LSIRTF-ASSGLIYYM--AH-QNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGK 468
Query: 3395 WHTVTLTRNGGHGKLAVDS-EMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFY 3453
WHTV G + VD E T V T L + +Y GGL ++ ++ N
Sbjct: 469 WHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLP--SQYQARKIGNIT 526
Query: 3454 QPFMGCLKGLLMNGQQVTRIG--NAVNALRCVDNIEDGVYFEASNNTHSNYLKLL-ENFK 3510
C+ + +N +Q+ + +A RC ++G YF+ S Y L+ E +K
Sbjct: 527 HSIPACIGDVTVNSKQLDKDSPVSAFTVNRCYAVAQEGTYFDGSG-----YAALVKEGYK 581
Query: 3511 VGDEVSISMEVRPRNTTGLLLSVH-GKKDYMVLELLDSEVVANVENGNGPFRATYKLSNK 3569
V +V+I++E R + G+LL + K D + LEL+D +V+ +V NG G A Y+
Sbjct: 582 VQSDVNITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTA 641
Query: 3570 HYLCDGNWHKIHXXXXXXXXXXXXDGHF--SKPGIGAYTSTDTHSALYIGGHERPIHKVR 3627
LCDG WH + DG+ ++ TS DT++ +Y+GG+ + K +
Sbjct: 642 TVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGV-KQK 700
Query: 3628 GVHSRRGFTGCVRNIVVGETP 3648
+ S+ F GC+R + + ++P
Sbjct: 701 CLRSQTSFRGCLRKLALIKSP 721
Score = 71.3 bits (167), Expect = 6e-11
Identities = 76/309 (24%), Positives = 123/309 (39%), Gaps = 34/309 (11%)
Query: 2696 DYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRE 2755
DY V+ + G + + D+G PA +++D +W+ V D + R+ +++
Sbjct: 434 DYAVLQLHGGRLHFMFDLGKGRTKVSHPA------LLSDGKWHTVKTDYVKRKGFITV-- 485
Query: 2756 SLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLYVGGVPSDAKLQGISFPAFEGQIEELMI 2815
D S + G T+ +++ Y+GG+PS + + I I
Sbjct: 486 ------DGRESPMVTVVGDGTMLDVE---GLFYLGGLPSQYQARKIGNITHS---IPACI 533
Query: 2816 GDTPVGLWNFVSANKLKGARQRDKLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLL 2875
GD V + + +Q G FDG GYA + GY + L
Sbjct: 534 GDVTVNSKQLDKDSPVSAFTVNRCYAVAQEGTY---FDGSGYAALVKEGYKVQSDVNITL 590
Query: 2876 FFRTYAPNGLIYLVGEGGY-FFSLLMQDGRVYLQVS--LGNTEDLIIVGTTRAYNDGKWH 2932
FRT + NG++ + L + DG+V V+ G T DGKWH
Sbjct: 591 EFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWH 650
Query: 2933 KLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMN---FGGNNKGILQV---PDRGF 2986
L A + + +L VD + AE SP S+DT N GG G+ Q F
Sbjct: 651 TLQANKSKHRITLIVDGNAVGAE--SPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSF 708
Query: 2987 DGCMRQISI 2995
GC+R++++
Sbjct: 709 RGCLRKLAL 717
Score = 63.7 bits (148), Expect = 1e-08
Identities = 84/352 (23%), Positives = 150/352 (42%), Gaps = 41/352 (11%)
Query: 2873 VLLFFRTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGK 2930
+++ F T++PNGL+ +G G F S+ + GRV + LG+ I + T R YN+G
Sbjct: 1 IIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGP--ITLLTDRRYNNGT 58
Query: 2931 WHKLDARRFLAKCSLTV-------DNEVLKAESNSPSADIPSL--DTMNFGGNNKGIL-- 2979
W+K+ +R + L V + E + E+ S+D+ L D + GG + +
Sbjct: 59 WYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVR 118
Query: 2980 -QVPDRGFDGCMRQISINGVNLDLSENLESIGMAYGCQFASL--VSFNGTDSYLRFVDVT 3036
V + F GC++ + I+ DL N S G+ GC + VSF Y+ +
Sbjct: 119 RGVTTKSFVGCIKNLEISRSTFDLLRN--SYGVRKGCLLEPIRSVSFL-KGGYIELPPKS 175
Query: 3037 -SENPQLTLKFKTAKPNGLLFVYV-------SRTQTAIMPDSISLSLVNGKLVV-VS--- 3084
S + + F T +G++ + + A +P S+ L+ G + V V+
Sbjct: 176 LSPESEWLVTFATTNSSGIILAALGGDVEKRGDREEAHVP-FFSVMLIGGNIEVHVNPGD 234
Query: 3085 ----QREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFD--YFSTDTAPPPLHILDGV 3138
++ L T +D Q H +++ N + + +D+ + T I
Sbjct: 235 GTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSN 294
Query: 3139 LFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
L++GG+ G S L + F GCI + N ++L+ + V C
Sbjct: 295 LYVGGIPEGEGTS-LLTMRRSFHGCIKNLIFNLELLDFNSAVGHEQVDLDTC 345
Score = 51.6 bits (118), Expect = 5e-05
Identities = 66/310 (21%), Positives = 122/310 (39%), Gaps = 26/310 (8%)
Query: 2873 VLLFFRTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGK 2930
V L RT+A +GLIY + + L + GR++ LG V +DGK
Sbjct: 411 VELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTK--VSHPALLSDGK 468
Query: 2931 WHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDRG----- 2985
WH + K +TVD + + ++ + + G Q G
Sbjct: 469 WHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHS 528
Query: 2986 FDGCMRQISINGVNLDLSENLES--IGMAYG-CQFASLVSFNGTDSYLRFVDVTSENPQL 3042
C+ +++N LD + + + Y Q + +G + ++ + +
Sbjct: 529 IPACIGDVTVNSKQLDKDSPVSAFTVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNI 588
Query: 3043 TLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLV--VVSQREQLDTGLNTYN--- 3097
TL+F+T+ NG+L + +S + D+I L LV+GK++ V + ++
Sbjct: 589 TLEFRTSSQNGVL-LGISTAKV----DAIGLELVDGKVLFHVNNGAGRITAAYEPKTATV 643
Query: 3098 --DSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI-LDGVLFIGGVQPGYVVSGSL 3154
D +WH L + + L+VD + + + +++GG P V L
Sbjct: 644 LCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGG-YPAGVKQKCL 702
Query: 3155 GSKVPFTGCI 3164
S+ F GC+
Sbjct: 703 RSQTSFRGCL 712
Score = 35.5 bits (78), Expect = 3.6
Identities = 78/345 (22%), Positives = 122/345 (35%), Gaps = 37/345 (10%)
Query: 3337 FRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYNDIDWH 3396
F TF G ++ Y S K+ FL+ + ++ M + G + + YN+ W+
Sbjct: 5 FNTFSPNG-LLLYLGSYGTKD---FLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWY 60
Query: 3397 TVTLTRNGGHGKLAV--------DSEMVGETSVTCNTPLSL-APPYYYGGL---RYVNER 3444
+ RN G LAV GET + L P Y GGL R V
Sbjct: 61 KIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRG 120
Query: 3445 ISKIFDNFYQPFMGCLKGL--------LMNGQQVTRIGNAVNALRCVDNIEDGVYFEASN 3496
++ + F+GC+K L L+ R G + +R V ++ G Y E
Sbjct: 121 VTT------KSFVGCIKNLEISRSTFDLLRNSYGVRKGCLLEPIRSVSFLKGG-YIELPP 173
Query: 3497 NTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKKDYMVLELLDSEVVANVENG 3556
+ S + L F + I + + + + L+ + +V G
Sbjct: 174 KSLSPESEWLVTFATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPG 233
Query: 3557 NGPFRATYKLSNKHYLC-DGNWHKIHXXXXXXXXXXXXDGH---FSKPGIGAYTSTDTHS 3612
+G L C DG H I D + K G + T S
Sbjct: 234 DGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVS 293
Query: 3613 ALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVG 3657
LY+GG + RR F GC++N++ + NSAVG
Sbjct: 294 NLYVGGIPEG-EGTSLLTMRRSFHGCIKNLIFNLELLDF-NSAVG 336
Score = 34.3 bits (75), Expect = 8.4
Identities = 35/153 (22%), Positives = 65/153 (42%), Gaps = 14/153 (9%)
Query: 3044 LKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLDTGLN---TYNDSQ 3100
L +T +GL++ + Q D L L G+L + + T ++ +D +
Sbjct: 413 LSIRTFASSGLIYYMAHQNQA----DYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGK 468
Query: 3101 WHVLTVTHNTSALKLVVDDFDY-FSTDTAPPPLHILDGVLFIGGVQPGYVVS--GSLGSK 3157
WH + + + VD + T + ++G+ ++GG+ Y G++
Sbjct: 469 WHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHS 528
Query: 3158 VPFTGCIGDATINGQVLNLLEPFSNNSVTFGRC 3190
+P CIGD T+N + L+ P S + T RC
Sbjct: 529 IP--ACIGDVTVNSKQLDKDSPVS--AFTVNRC 557
>AF131842-1|AAD20057.1| 260|Homo sapiens Unknown protein.
Length = 260
Score = 124 bits (299), Expect = 6e-27
Identities = 75/235 (31%), Positives = 102/235 (43%), Gaps = 34/235 (14%)
Query: 217 RYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKK 276
+YFY+I +I + GRC CN HA+ C + G+L C C+HNT GP C KC F +
Sbjct: 3 KYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CECEHNTTGPDCGKCKKNFRTRS 57
Query: 277 WRISQ-----NWDRFSCEP------CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKC 325
WR + +C C C+ H+ C+Y ID + C
Sbjct: 58 WRAGSYLPLPHGSPNACAAAGSFGNCECYGHSNRCSY---ID-----------FLNVVTC 103
Query: 326 LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEF 385
++C+HNT G +C CR YYR D+ +VC C C+ S + E+G CECR
Sbjct: 104 VSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGA 163
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCN---LNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
P C C ++ C P C+ L G C C C Y G CE
Sbjct: 164 AGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQ-RCACPRGYTGVRCE 217
Score = 83.0 bits (196), Expect = 2e-14
Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 41/212 (19%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 11 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 70
Query: 405 PCTCNLNGTEGE--------HCTPTDGL----C-PCKYNYAGKSCEICEDGYY---SPE- 447
P C G+ G C+ D L C CK+N G+ C+ C GYY S E
Sbjct: 71 PNACAAAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 130
Query: 448 -----CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C C CN +GSV C++ TG C C+ +G C+ C +Y C P CD
Sbjct: 131 DDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCD-- 187
Query: 503 GTEPSICDD-----VSGQCICKAGFGGPRCDQ 529
+ +C + + +C C G+ G RC+Q
Sbjct: 188 -DDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 218
Score = 81.4 bits (192), Expect = 6e-14
Identities = 63/222 (28%), Positives = 85/222 (38%), Gaps = 27/222 (12%)
Query: 428 KYNYAGKSCEI---CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTC-KSKYSGRTCNQ 483
KY YA + E+ C+ ++ C E GS+ C+ T C K K + RT +
Sbjct: 3 KYFYAISNIEVIGRCKCNLHANLCSMRE----GSLQCECEHNTTGPDCGKCKKNFRTRSW 58
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSI-CDDVSGQCI------------CKAGFGGPRCDQC 530
Y P P C +G+ + C S +C CK G C C
Sbjct: 59 RAGSYLPLPHGSPNACAAAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHC 118
Query: 531 LSGYYMQ---VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
GYY L E C+ CNC+ GS C+ G C C G +CD C P +Y
Sbjct: 119 RLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWR 178
Query: 588 PDCLSCNCDVSGSI---GSTCDDNGLCHCKSNFDGAKCDTCR 626
C CD + G TC N C C + G +C+ R
Sbjct: 179 QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 220
Score = 76.2 bits (179), Expect = 2e-12
Identities = 65/209 (31%), Positives = 87/209 (41%), Gaps = 34/209 (16%)
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYC----------AAGYYGIPEDTD---LHT 1870
N A C + E GSL C C+ G C C A Y +P +
Sbjct: 20 NLHANLCSMRE-GSL-QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAA 77
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSING-DCLKCVNNTAGAACNLCAPGFY--GDA-IFSKN 1926
G + C C G+ N D +N C+ C +NT G C C G+Y G A + +N
Sbjct: 78 GSFGN-CECYGHSNRCS--YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 134
Query: 1927 -CTACICDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASE 1984
C C C++ G D + TG C CR G G KCD C P H+ GC P C +
Sbjct: 135 VCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVCD--DD 189
Query: 1985 STQCDD-----DNGQCRCAKGVTGKQCDQ 2008
C + N +C C +G TG +C+Q
Sbjct: 190 QLLCQNGGTCLQNQRCACPRGYTGVRCEQ 218
Score = 68.1 bits (159), Expect = 6e-10
Identities = 61/199 (30%), Positives = 80/199 (40%), Gaps = 36/199 (18%)
Query: 1341 LCDFM-GSTELEC--NTFGGQC-PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI--- 1393
LC GS + EC NT G C CK N RT S Y P+ P C +
Sbjct: 25 LCSMREGSLQCECEHNTTGPDCGKCKKNF--RTRSWRAGSYLPLPHGSPNACAAAGSFGN 82
Query: 1394 CDDNG--------------MCI-CPKNVEGENCDRCK-PYTFN----FDVQRGCDDCNCN 1433
C+ G C+ C N G++C C+ Y N D + C +CNCN
Sbjct: 83 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 142
Query: 1434 PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD---VC 1490
+G V ++ C ++G C CRE G CD C+P HY CY C+ C
Sbjct: 143 QIGSVHDR--CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 199
Query: 1491 DQNTAQCYCKTNVRGQACD 1509
QN +C C G C+
Sbjct: 200 LQN-QRCACPRGYTGVRCE 217
Score = 64.1 bits (149), Expect = 9e-09
Identities = 54/210 (25%), Positives = 76/210 (36%), Gaps = 32/210 (15%)
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCL---------SGYYMQVL-GRERQCV 546
C C+ S+ + S QC C+ GP C +C +G Y+ + G C
Sbjct: 17 CKCNLHANLCSMREG-SLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 75
Query: 547 PC----NCDPTGSTSTSCSADG----KC-NCLTNFGGAQCDQCSPGYYKYPD-------- 589
NC+ G ++ D C +C N G C C GYY+
Sbjct: 76 AAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV 135
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C+ CNC+ GS+ C++ G C C+ G KCD C Y C CD +
Sbjct: 136 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ- 194
Query: 650 AGCGSVPAGELCQCKDRVQGRICND--CKP 677
G+ + C C G C C P
Sbjct: 195 -NGGTCLQNQRCACPRGYTGVRCEQPRCDP 223
Score = 61.3 bits (142), Expect = 6e-08
Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 23/153 (15%)
Query: 654 SVPAGEL-CQCKDRVQGRICNDCKPLY----WNLQEYNPFGCEQCN-CNLAGTLNSLGAC 707
S+ G L C+C+ G C CK + W Y P N C AG+ + C
Sbjct: 27 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGNC-EC 85
Query: 708 NTKSGQCV------------CKQHVGERQCDQCLDGFYR---LQTNDVFGCTECDCDIGG 752
S +C CK + + C C G+YR + +D C EC+C+ G
Sbjct: 86 YGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 145
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYF 785
S+ + C++T G C C G +CD + HY+
Sbjct: 146 SVHDRCNET-GFCECREGAAGPKCDDCLPTHYW 177
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 36/213 (16%)
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY-------NYPACEECNCDPRGV 645
C C++ ++ S + + C C+ N G C C++ F +Y + +
Sbjct: 17 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAA 76
Query: 646 TASFAGCGSVPAGELCQ------------CKDRVQGRICNDCKPLYWN-----LQEYNPF 688
SF C C CK +G+ C C+ Y+ L + N
Sbjct: 77 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 135
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C +CNCN G+++ CN ++G C C++ +CD CL Y Q GC C
Sbjct: 136 -CIECNCNQIGSVHD--RCN-ETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVC 186
Query: 749 DIGGSIDNNCDKT--TGQCHCHSRVEGRRCDQP 779
D + N +C C G RC+QP
Sbjct: 187 DDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 219
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 29/154 (18%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRGC-------DDCNCNPLGVVGNQLQCEADSGKCA 1452
C C N G +C +CK + G C G GN +C S +C+
Sbjct: 35 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAAAGSFGN-CECYGHSNRCS 93
Query: 1453 ------------CRENVRGRVCDHCVPGHYA-----FPD---CYQCTCNRHGTTYDVCDQ 1492
C+ N RG+ C HC G+Y D C +C CN+ G+ +D C++
Sbjct: 94 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 153
Query: 1493 NTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
T C C+ G CD C ++ Q P+ C
Sbjct: 154 -TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 186
Score = 59.3 bits (137), Expect = 3e-07
Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGYH--GDATVGTPRDCLICACP 1818
C+C GHS++C +N C++C NT G HC+ C GY+ G A + C+ C C
Sbjct: 83 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC- 141
Query: 1819 MPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCEYCAAGYY 1860
N D +E G C C+ G G +C+ C +Y
Sbjct: 142 -----NQIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHY 176
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 15/142 (10%)
Query: 1946 TCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRCA 1998
TCV C+ G+ C C ++ L+ C CNC I S +C++ G C C
Sbjct: 102 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECR 160
Query: 1999 KGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV---GFMCNATGQCECLPGVIGEKCDR 2055
+G G +CD C +Y + GC C+ + G C +C C G G +C++
Sbjct: 161 EGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ 218
Query: 2056 CPERWVLIPQEGCLECDSCTDA 2077
R +G L+CD A
Sbjct: 219 --PRCDPADDDGGLDCDRAPGA 238
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRP--CH-----CPSTA 1392
C C+ +GS CN G C C+ G C C +Y C P C C +
Sbjct: 139 CNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 197
Query: 1393 ICDDNGMCICPKNVEGENCD--RCKP 1416
C N C CP+ G C+ RC P
Sbjct: 198 TCLQNQRCACPRGYTGVRCEQPRCDP 223
Score = 41.1 bits (92), Expect = 0.073
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 28/128 (21%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG C+ C G+YR S C+ C CN D+C+ TG C C +
Sbjct: 106 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFC-ECREGA 163
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS---CNCQP 1845
G C+ C+ ++ + C C ++ L C G+ + C C
Sbjct: 164 AGPKCDDCLPTHY------WRQGCYPNVC------DDDQLLC--QNGGTCLQNQRCACPR 209
Query: 1846 GYGGARCE 1853
GY G RCE
Sbjct: 210 GYTGVRCE 217
Score = 37.5 bits (83), Expect = 0.90
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 17/79 (21%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE----------EYFNLQDDNPDGC 1526
+C CN H + + + QC C+ N G C CK+ Y L +P+ C
Sbjct: 16 RCKCNLHANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 74
Query: 1527 T------KCFCFGKTTRCS 1539
C C+G + RCS
Sbjct: 75 AAAGSFGNCECYGHSNRCS 93
Score = 35.1 bits (77), Expect = 4.8
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 1478 CTCNRHGTTYDVCD-QNTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFC 1531
C C H D N C CK N RGQ C C+ Y+ + + D+ + C +C C
Sbjct: 83 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 141
>AB208853-1|BAD92090.1| 1408|Homo sapiens Laminin alpha 3b chain
variant protein.
Length = 1408
Score = 124 bits (299), Expect = 6e-27
Identities = 153/764 (20%), Positives = 312/764 (40%), Gaps = 66/764 (8%)
Query: 2387 LTSEATHHATMLRRRADSLRELAERENNNSRTQHXXXXXXXXXXXXQEINXXXXXXXXXX 2446
L EA HA L+ A L E+ + + + I
Sbjct: 213 LVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAA 272
Query: 2447 XXXXNV--TKLNRILDERVRPARERSSSLLADATKAQHAVDQKLLPNLTATEEVLRKIRD 2504
+ T + L + + S LL +A Q + Q++ P L ++ L +
Sbjct: 273 SASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTV 332
Query: 2505 HLSRADDDDNAIQXXXXXXXXXXXXXXXNKA-DRVNATIGTTFSVMSHLGPELATSKDWA 2563
D + ++ + A V T V+ L P +
Sbjct: 333 QKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIK 392
Query: 2564 QTLPKLADEG-QKMTSNVESHLKNINDMEPQISSSYHTVKMXXXXXXXXXXXXXXKLQKL 2622
T + +E +K ++ ++ + + + P + ++ + ++
Sbjct: 393 DTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISD----NMDRI 448
Query: 2623 KDLVEQARTVANRIQVGVTFDRWSTLQPRLPDTVDEMSTSTHVSAYFR---TKEKDG--- 2676
++L++QAR A+++ V + F+ S ++ RLP+ ++++ T +S + + ++E G
Sbjct: 449 RELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTEN 508
Query: 2677 -FILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSIDKMVADN 2735
F++YLGN + S DY+ + + +G V ++GD A + +D+++ +
Sbjct: 509 MFVMYLGN-------KDASRDYIGMAVVDGQLTCVYNLGDRE------AELQVDQILTKS 555
Query: 2736 RWYQVIVDRLG-RRVKLSIRESLDNGTDTIHSKEA---DLPGH--HTIFNLDKEKSKLYV 2789
+ ++DR+ +R+ R + G + + D+ G +T+ NLD E YV
Sbjct: 556 ETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYV 615
Query: 2790 GGVPSDAKLQG-ISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQSGPQ 2848
GG P D KL +SFP ++G IE + + + L+NF L + +
Sbjct: 616 GGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDK 675
Query: 2849 EYRFDGRGYATMAGRGYL-TPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYL 2907
Y F+G GYA + + + P Q + +T GL++ G F SL ++DG++ +
Sbjct: 676 NY-FEGTGYARVPTQPHAPIPTFGQTI---QTTVDRGLLFFAENGDRFISLNIEDGKLMV 731
Query: 2908 QVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLD 2967
+ L N+E G A N+G+ H + + + + ++ +V ++ ++
Sbjct: 732 RYKL-NSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDV---QNTIIDGEVFDFS 787
Query: 2968 TMNFGGNNKGI---LQVPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC----QFASL 3020
T GG I + F GCM+ + + L+ +++G+ C +
Sbjct: 788 TYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLN---DTVGVTKKCSEDWKLVRS 844
Query: 3021 VSFNGTDSYLRFVDV---TSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVN 3077
SF+ L F D+ +++ Q + F+T +P+G+L + + T+ ++ ++L +
Sbjct: 845 ASFS-RGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTR------NLQVTLED 897
Query: 3078 G--KLVVVSQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD 3119
G +L + TY D H ++V + S L+L++DD
Sbjct: 898 GYIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDD 941
Score = 104 bits (249), Expect = 7e-21
Identities = 89/363 (24%), Positives = 160/363 (44%), Gaps = 24/363 (6%)
Query: 3309 RFGSRNVSRIEYAKLPGRQLEG-FDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMR 3367
+FG S + + KLP L+ + +T +G ++F+ + KN F+A ++
Sbjct: 1063 QFGDIPTSHLLF-KLPQELLKPRSQFAVDMQTTSSRG-LVFHTGT---KN--SFMALYLS 1115
Query: 3368 DAKLHYMFNCGGETGVISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPL 3427
+L + G+ I S ND WHTV +G G+L VD E S+ N+ +
Sbjct: 1116 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 1175
Query: 3428 SLAPPYYYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNALRCVDN-I 3486
S+ P Y G + + + N F+GCLK ++ + + ++ C+ +
Sbjct: 1176 SIRAPVYLGS--PPSGKPKSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 1230
Query: 3487 EDGVYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK-DYMVLELL 3545
E G+YF + ++ L + +G E + +RPR+ TG+L+ + + ++ + L
Sbjct: 1231 EKGIYF----SEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1286
Query: 3546 DSEVVANVENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFS-KPGIGA 3604
+V A++++G G + ++ K LCDG WH + D S G
Sbjct: 1287 AGKVTASMDSGAG--GTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIP 1344
Query: 3605 YTSTDTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRG-AHVG 3663
+ T L++GG + +R + + F GC+RNI V PV V + +G +
Sbjct: 1345 FPPASTQEPLHLGGAPANLTTLR-IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 1403
Query: 3664 VCP 3666
CP
Sbjct: 1404 GCP 1406
Score = 50.8 bits (116), Expect = 9e-05
Identities = 60/292 (20%), Positives = 118/292 (40%), Gaps = 30/292 (10%)
Query: 2725 RVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEK 2784
R+ + D +W+ V+ G + +L + D + ++E LPG+ TI +
Sbjct: 1131 RIKSKEKCNDGKWHTVVFGHDGEKGRLVV--------DGLRAREGSLPGNSTI----SIR 1178
Query: 2785 SKLYVGGVPSDAKLQGISFPAFEGQIEELMIGDTPVGLWNFVSANKLKGARQRDKLISSQ 2844
+ +Y+G PS K + + +F G ++ + P+ + ++ + S
Sbjct: 1179 APVYLGSPPS-GKPKSLPTNSFVGCLKNFQLDSKPL----YTPSSSFG-------VSSCL 1226
Query: 2845 SGPQE---YRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQ 2901
GP E Y + G+ +A L P+ V LI++ + G + ++
Sbjct: 1227 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1286
Query: 2902 DGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSA 2961
G+V + G V ++ DG+WH + L +D + P
Sbjct: 1287 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 1346
Query: 2962 DIPSLDTMNFGG--NNKGILQVPD-RGFDGCMRQISINGVNLDLSENLESIG 3010
+ + ++ GG N L++P + F GC+R I +N + + ++E LE G
Sbjct: 1347 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 1398
Score = 50.0 bits (114), Expect = 2e-04
Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 9/309 (2%)
Query: 2866 LTPQSNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
L P+S Q + +T + GL++ G F +L + GR L +LG + + +
Sbjct: 1081 LKPRS-QFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGR--LVFALGTDGKKLRIKSKEK 1137
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKG-ILQVPDR 2984
NDGKWH + K L VD + S ++ I + G G +P
Sbjct: 1138 CNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTN 1197
Query: 2985 GFDGCMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTL 3044
F GC++ ++ L + + G + F+ ++ P+ L
Sbjct: 1198 SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKL 1257
Query: 3045 KFKTAKPNGL--LFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLD-TGLNTYNDSQW 3101
F + +P L + +++ + + V + + T + D QW
Sbjct: 1258 VF-SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQW 1316
Query: 3102 HVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYVVSGSLGSKVPFT 3161
H + VT L L +D ++ P P L +GG P + + + F
Sbjct: 1317 HSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGA-PANLTTLRIPVWKSFF 1375
Query: 3162 GCIGDATIN 3170
GC+ + +N
Sbjct: 1376 GCLRNIHVN 1384
>AL590103-9|CAI12132.1| 196|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 196
Score = 116 bits (279), Expect = 2e-24
Identities = 59/157 (37%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Query: 1760 GFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPM 1819
G C C C+GHS+ C+ TG C C +T G CE C GY+GDA GTP+DC +C C
Sbjct: 8 GTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYG 67
Query: 1820 PYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC 1879
+ A +C L +G C PG+ G CE CA GYYG P D P
Sbjct: 68 DPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPI 127
Query: 1880 SGNINPQDPGS--CDSINGDCLKCVNNTAGAACNLCA 1914
N +PQ S CD+ G C +C + C C+
Sbjct: 128 GCNCDPQGSVSSQCDAA-GQC-QCKVSPNPCPCGACS 162
Score = 85.0 bits (201), Expect = 5e-15
Identities = 53/156 (33%), Positives = 70/156 (44%), Gaps = 26/156 (16%)
Query: 493 TCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYYMQVL-GRERQCVPCNC 550
TC+ C+C C+ +G C C+ GPRC+QC GYY G + C C C
Sbjct: 9 TCERCSCHGHS---EACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPC 65
Query: 551 --DPT-GSTSTSC--SADGK--CN-CLTNFGGAQCDQCSPGYYKYPD----C-------- 590
DP G + +C DG C+ C G C++C+PGYY P C
Sbjct: 66 YGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPG 125
Query: 591 -LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTC 625
+ CNCD GS+ S CD G C CK + + C C
Sbjct: 126 PIGCNCDPQGSVSSQCDAAGQCQCKVSPNPCPCGAC 161
Score = 81.8 bits (193), Expect = 4e-14
Identities = 54/162 (33%), Positives = 67/162 (41%), Gaps = 25/162 (15%)
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCT-CKSKYSGRTCNQCQAGYYNYPT------C 494
G Y C+ C C+ S C+ TG C C+ G C QCQ GYY C
Sbjct: 4 GLYLGTCERCSCH---GHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDC 60
Query: 495 KPCNC---DTSGTEPSICD-DVSGQCICKA---GFGGPRCDQCLSGYYM-----QVLGRE 542
+ C C +G C D G C A G G C++C GYY Q R+
Sbjct: 61 QLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRD 120
Query: 543 RQC---VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
Q + CNCDP GS S+ C A G+C C + C CS
Sbjct: 121 SQVPGPIGCNCDPQGSVSSQCDAAGQCQCKVSPNPCPCGACS 162
Score = 73.3 bits (172), Expect = 1e-11
Identities = 53/160 (33%), Positives = 70/160 (43%), Gaps = 28/160 (17%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACI 1931
C+ C+C G+ +C+ G C C ++T G C C PG+YGDA ++C C
Sbjct: 10 CERCSCHGHSE-----ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCP 64
Query: 1932 C---DEFGMA------DCDSTTGTCVCRPGVIGEKCDRCAPDHWG-LNTGLGC-----TP 1976
C G A D D C PG G C+RCAP ++G + G C P
Sbjct: 65 CYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVP 124
Query: 1977 ----CNCG-IASESTQCDDDNGQCRCAKGVTGKQCDQCAA 2011
CNC S S+QC D GQC+C C C+A
Sbjct: 125 GPIGCNCDPQGSVSSQC-DAAGQCQCKVSPNPCPCGACSA 163
Score = 73.3 bits (172), Expect = 1e-11
Identities = 48/171 (28%), Positives = 77/171 (45%), Gaps = 26/171 (15%)
Query: 230 RCMCNGHADTCEPADPAGNLNILVCR-CQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
RC C+GH++ CEP A C+ CQH+T GP+C +C G+ + +Q C
Sbjct: 12 RCSCHGHSEACEPETGA-------CQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDC 60
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY-RP 347
+ C C+ DP + + ++ +G C C G +C +C P YY P
Sbjct: 61 QLCPCYG-------DPAAGQAAHTCFLDT--DGHPTCDACSPGHSGRHCERCAPGYYGNP 111
Query: 348 YGKRWDELDVCQP----CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCA 394
+ + D P C CDP S + + +G+C+C+ P C +C+
Sbjct: 112 SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKVSPNPCPCGACS 162
Score = 66.5 bits (155), Expect = 2e-09
Identities = 59/211 (27%), Positives = 78/211 (36%), Gaps = 50/211 (23%)
Query: 287 SCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYR 346
+CE C+CH H+ C +PE G C CQH+TEG C +C+P YY
Sbjct: 9 TCERCSCHGHSEAC--EPET----------------GACQGCQHHTEGPRCEQCQPGYYG 50
Query: 347 PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPC 406
+R D CQ C C + G +C +P C C
Sbjct: 51 D-AQRGTPQD-CQLCPCYGDPAAGQA-----------------AHTCFLDTDGHPTCDAC 91
Query: 407 TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKL 466
+ G G HC + P Y + + C+ P C C+ GSVS CD
Sbjct: 92 S---PGHSGRHC---ERCAPGYYGNPSQG-QPCQRDSQVPGPIGCNCDPQGSVSSQCD-A 143
Query: 467 TGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC 497
G C CK + C C A P +PC
Sbjct: 144 AGQCQCKVSPNPCPCGACSA-----PLPRPC 169
Score = 65.7 bits (153), Expect = 3e-09
Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 24/146 (16%)
Query: 1922 IFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG---LNTGLGCTPC 1977
++ C C C A C+ TG C C+ G +C++C P ++G T C C
Sbjct: 5 LYLGTCERCSCHGHSEA-CEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLC 63
Query: 1978 NC------GIASESTQCDDD-NGQC-RCAKGVTGKQCDQCAAGFWNYTKDG--CDH---- 2023
C G A+ + D D + C C+ G +G+ C++CA G++ G C
Sbjct: 64 PCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQV 123
Query: 2024 -----CNCNTGYSVGFMCNATGQCEC 2044
CNC+ SV C+A GQC+C
Sbjct: 124 PGPIGCNCDPQGSVSSQCDAAGQCQC 149
Score = 59.3 bits (137), Expect = 3e-07
Identities = 45/149 (30%), Positives = 58/149 (38%), Gaps = 25/149 (16%)
Query: 1386 CHCPSTAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG----CDDCNCNPLGVVGN 1440
CH S A + G C C + EG C++C+P + D QRG C C C G
Sbjct: 15 CHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQ 73
Query: 1441 QLQ-CEADSG---KC-ACRENVRGRVCDHCVPGHYAFPD----CYQ---------CTCNR 1482
C D+ C AC GR C+ C PG+Y P C + C C+
Sbjct: 74 AAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDP 133
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTC 1511
G+ CD QC CK + C C
Sbjct: 134 QGSVSSQCDA-AGQCQCKVSPNPCPCGAC 161
Score = 52.4 bits (120), Expect = 3e-05
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 23/148 (15%)
Query: 635 CEECNCDPRGVTASFAGCGSVPAGELCQ-CKDRVQGRICNDCKPLYW-NLQEYNPFGCEQ 692
CE C+C P CQ C+ +G C C+P Y+ + Q P C+
Sbjct: 10 CERCSCHGHSEACE-------PETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQL 62
Query: 693 CNCN---LAGTLNSLGACNTKSGQ-C-VCKQHVGERQCDQCLDGFYR--------LQTND 739
C C AG +T C C R C++C G+Y + +
Sbjct: 63 CPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQ 122
Query: 740 VFGCTECDCDIGGSIDNNCDKTTGQCHC 767
V G C+CD GS+ + CD GQC C
Sbjct: 123 VPGPIGCNCDPQGSVSSQCD-AAGQCQC 149
Score = 45.6 bits (103), Expect = 0.003
Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 16/114 (14%)
Query: 1967 GLNTGLGCTPCNCGIASESTQCDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTKDG----C 2021
GL G C C+C SE+ C+ + G C+ C G +C+QC G++ + G C
Sbjct: 4 GLYLGT-CERCSCHGHSEA--CEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDC 60
Query: 2022 DHCNCNTGYSVG---FMC--NATGQ--CE-CLPGVIGEKCDRCPERWVLIPQEG 2067
C C + G C + G C+ C PG G C+RC + P +G
Sbjct: 61 QLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQG 114
Score = 45.6 bits (103), Expect = 0.003
Identities = 40/138 (28%), Positives = 53/138 (38%), Gaps = 19/138 (13%)
Query: 1736 CQ-CPRAYRGLSCEQCAEGHY----RLPSGFCVPCQCNGH------SDQCDVNTG---IC 1781
CQ C G CEQC G+Y R C C C G + C ++T C
Sbjct: 29 CQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTC 88
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTP--RDCLICACPMPYPSNNFALSCDLSENGSLI 1839
C+ G HCE C GY+G+ + G P RD + P P N S+ +
Sbjct: 89 DACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQV---PGPIGCNCDPQGSVSSQCDAAG 145
Query: 1840 SCNCQPGYGGARCEYCAA 1857
C C+ C C+A
Sbjct: 146 QCQCKVSPNPCPCGACSA 163
Score = 38.3 bits (85), Expect = 0.52
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 14/104 (13%)
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGERQCDQCLDGFY-RLQTNDVFGCTECD 747
CE+C+C+ AC ++G C C+ H +C+QC G+Y Q C C
Sbjct: 10 CERCSCH-----GHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCP 64
Query: 748 C---DIGGSIDNNCDKTTG---QCH-CHSRVEGRRCDQPIRAHY 784
C G + C T C C GR C++ +Y
Sbjct: 65 CYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYY 108
Score = 34.7 bits (76), Expect = 6.4
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 13/82 (15%)
Query: 1305 EQCASYNYYISPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPN 1364
E+CA YY +P++ C+ G C CD GS +C+ GQC CK +
Sbjct: 101 ERCAP-GYYGNPSQGQPCQR------DSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKVS 152
Query: 1365 VIGRTCSACRTGYYGFPNCRPC 1386
C AC P RPC
Sbjct: 153 PNPCPCGACSA-----PLPRPC 169
>AY358365-1|AAQ88731.1| 438|Homo sapiens YLSR571 protein.
Length = 438
Score = 115 bits (276), Expect = 4e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFALFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 40.7 bits (91), Expect = 0.097
Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC---------SPG-YYKYPDCLSCNCDV 597
C C+ + ++ C C N G C +C SPG Y P + C
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 598 S-GSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCG 653
S SIG+ DN L HC++ + +C C Y CE+ C+ G S +G G
Sbjct: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRC-LC-PAAYTGILCEKLRCEEAGSCGSDSGQG 414
Query: 654 SVPAG 658
+ P G
Sbjct: 415 APPHG 419
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>BX538348-1|CAD98143.1| 365|Homo sapiens hypothetical protein
protein.
Length = 365
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>BC030220-1|AAH30220.1| 438|Homo sapiens netrin G1 protein.
Length = 438
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 40.7 bits (91), Expect = 0.097
Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC---------SPG-YYKYPDCLSCNCDV 597
C C+ + ++ C C N G C +C SPG Y P + C
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 598 S-GSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCG 653
S SIG+ DN L HC++ + +C C Y CE+ C+ G S +G G
Sbjct: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRC-LC-PAAYTGILCEKLRCEEAGSCGSDSGQG 414
Query: 654 SVPAG 658
+ P G
Sbjct: 415 APPHG 419
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AL590427-4|CAH73385.1| 480|Homo sapiens netrin G1 protein.
Length = 480
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
Score = 35.5 bits (78), Expect = 3.6
Identities = 37/164 (22%), Positives = 54/164 (32%), Gaps = 14/164 (8%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C+ H + + CEC PDC C Y P + C P
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 421 TDGLC--PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY-- 476
+ P K+N + E +TV SV K C + +
Sbjct: 357 SISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQ 416
Query: 477 SGRTCNQ-----CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ 515
+G TC+ C A Y C+ C+ +G+ C SGQ
Sbjct: 417 NGGTCHNNVRCLCPAAYTGI-LCEKLRCEEAGS----CGSDSGQ 455
>AL590427-3|CAH73384.1| 460|Homo sapiens netrin G1 protein.
Length = 460
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AL590427-2|CAH73383.1| 438|Homo sapiens netrin G1 protein.
Length = 438
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 40.7 bits (91), Expect = 0.097
Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC---------SPG-YYKYPDCLSCNCDV 597
C C+ + ++ C C N G C +C SPG Y P + C
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 598 S-GSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCG 653
S SIG+ DN L HC++ + +C C Y CE+ C+ G S +G G
Sbjct: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRC-LC-PAAYTGILCEKLRCEEAGSCGSDSGQG 414
Query: 654 SVPAG 658
+ P G
Sbjct: 415 APPHG 419
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AL590427-1|CAH73380.1| 364|Homo sapiens netrin G1 protein.
Length = 364
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AL513187-6|CAH73833.1| 460|Homo sapiens netrin G1 protein.
Length = 460
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AL513187-5|CAH73832.1| 438|Homo sapiens netrin G1 protein.
Length = 438
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 40.7 bits (91), Expect = 0.097
Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC---------SPG-YYKYPDCLSCNCDV 597
C C+ + ++ C C N G C +C SPG Y P + C
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 598 S-GSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCG 653
S SIG+ DN L HC++ + +C C Y CE+ C+ G S +G G
Sbjct: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRC-LC-PAAYTGILCEKLRCEEAGSCGSDSGQG 414
Query: 654 SVPAG 658
+ P G
Sbjct: 415 APPHG 419
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AL513187-2|CAH73829.1| 480|Homo sapiens netrin G1 protein.
Length = 480
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
Score = 35.5 bits (78), Expect = 3.6
Identities = 37/164 (22%), Positives = 54/164 (32%), Gaps = 14/164 (8%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C+ H + + CEC PDC C Y P + C P
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 421 TDGLC--PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY-- 476
+ P K+N + E +TV SV K C + +
Sbjct: 357 SISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQ 416
Query: 477 SGRTCNQ-----CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ 515
+G TC+ C A Y C+ C+ +G+ C SGQ
Sbjct: 417 NGGTCHNNVRCLCPAAYTGI-LCEKLRCEEAGS----CGSDSGQ 455
>AL513187-1|CAH73828.1| 364|Homo sapiens netrin G1 protein.
Length = 364
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 92 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 151
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 152 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 210
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 211 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 270
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 271 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 319
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 320 NTTGPDCGKCKKNYQGRPW 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 296 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 333
>AB023193-1|BAA76820.2| 386|Homo sapiens KIAA0976 protein protein.
Length = 386
Score = 114 bits (275), Expect = 5e-24
Identities = 80/259 (30%), Positives = 126/259 (48%), Gaps = 30/259 (11%)
Query: 37 CDANNEAKKHPPEYAVDDR----RTWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+ HPPE D T+WQS K +VN+T+ + + V
Sbjct: 114 CDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVIT 173
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDD--SVICSTEY 150
S RP+ +LEKS DYG+T++P+QY++ D + +S++ +++ +IC+ EY
Sbjct: 174 FESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF-HMDPKSVKDLSQHTVLEIICTEEY 232
Query: 151 S-------KIVPLE--DGEIPISLLNDRPSSNMYFN---SSVLQEWTRATNVRLRLLRTK 198
S KI+ E D + R +++Y + L+++ T++R+RLLR
Sbjct: 233 STGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPA 292
Query: 199 NLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCRCQH 258
+G + D RYFY+I DI + GRC CN HA C + + L C C+H
Sbjct: 293 --VGEIFV----DELHLARYFYAISDIKVRGRCKCNLHATVC-----VYDNSKLTCECEH 341
Query: 259 NTCGPQCNKCCSGFEQKKW 277
NT GP C KC ++ + W
Sbjct: 342 NTTGPDCGKCKKNYQGRPW 360
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
+C CN H T V D + C C+ N G C CK+ Y
Sbjct: 318 RCKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNY 355
>AY358165-1|AAQ88532.1| 422|Homo sapiens LHLL9381 protein.
Length = 422
Score = 114 bits (274), Expect = 7e-24
Identities = 85/263 (32%), Positives = 127/263 (48%), Gaps = 35/263 (13%)
Query: 37 CDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKYNEVNLTIDLGQEFHVAYVFVKM 92
CDA+N HPP D T+WQS SR E N+T+ + + V
Sbjct: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
Query: 93 GNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDS----VICST 148
RP + VLEKS D G+T++P+Q++++ DC FG + + S V+C+
Sbjct: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
Query: 149 EYSKIVPLEDGEIPISLLNDR------PS----SNMYF---NSSVLQEWTRATNVRLRLL 195
EYS+ + + + DR P N+Y ++ L+E+ T++R+RLL
Sbjct: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
Query: 196 RTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCEPADPAGNLNILVCR 255
R LG V R++ +YFY+I +I + GRC CN HA+ C + G+L C
Sbjct: 258 RPA--LGGTY-VQREN---LYKYFYAISNIEVIGRCKCNLHANLCSMRE--GSLQ---CE 306
Query: 256 CQHNTCGPQCNKCCSGFEQKKWR 278
C+HNT GP C KC F + WR
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWR 329
Score = 39.1 bits (87), Expect = 0.30
Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 10/82 (12%)
Query: 355 LDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSC----------AYGYFDYPNCK 404
++V C+C+ H + + E S +CEC PDC C A Y P+
Sbjct: 281 IEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
Query: 405 PCTCNLNGTEGEHCTPTDGLCP 426
P C G+ G TP G P
Sbjct: 341 PNACAAAGSFGTLQTPPPGRSP 362
>BC033207-1|AAH33207.1| 489|Homo sapiens hypothetical protein
BC018697 protein.
Length = 489
Score = 113 bits (271), Expect = 2e-23
Identities = 58/170 (34%), Positives = 81/170 (47%), Gaps = 13/170 (7%)
Query: 229 GRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
GRC C+GHA C A C C+H+T GP C C WR + C
Sbjct: 155 GRCQCHGHAARC-----AARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPC 209
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPY 348
PC+C+ H C ++ E+ RLS GR GG C C+H+T G +C+ C+P ++R
Sbjct: 210 LPCSCNQHARRCRFNSEL--FRLS---GGR--SGGVCERCRHHTAGRHCHYCQPGFWRDP 262
Query: 349 GKRWDELDVCQPCQCDPHFST-GNCEEESGRCECRPEFQPPDCSSCAYGY 397
+ C+ CQC P +T G C + SG+C C+ C+ C GY
Sbjct: 263 SQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 83.8 bits (198), Expect = 1e-14
Identities = 45/156 (28%), Positives = 70/156 (44%), Gaps = 28/156 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNL 410
CQC H + RC CR P C SC + D+P C PC+CN
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 411 NGTEGEHCTP--------TDGLCP-CKYNYAGKSCEICEDGYY-SPE--------CKNCE 452
+ + + G+C C+++ AG+ C C+ G++ P C+ C+
Sbjct: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C+ +G+ C++ +G CTCK +G TCN+C GY
Sbjct: 277 CHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 73.7 bits (173), Expect = 1e-11
Identities = 47/139 (33%), Positives = 65/139 (46%), Gaps = 15/139 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP--EDTDLHTGDYCKPCNCSGN-----INPQ-DPGSCD 1892
C+C+ G CE C + P T H C PC+C+ + N + S
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD--CDSTTGT 1946
G C +C ++TAG C+ C PGF+ D IFS+ C AC C G C+ T+G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 1947 CVCRPGVIGEKCDRCAPDH 1965
C C+ GV G C+RC P +
Sbjct: 294 CTCKLGVTGLTCNRCGPGY 312
Score = 66.9 bits (156), Expect = 1e-09
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 20/140 (14%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG----CGSVP 656
CHC+ + G C++CR ++P C C+C+ F
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 657 AGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFG---CEQCNCNLAGTLNSLGACNTKSG 712
+G +C+ C+ GR C+ C+P +W F C C C+ G G CN SG
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATG--GTCNQTSG 292
Query: 713 QCVCKQHVGERQCDQCLDGF 732
QC CK V C++C G+
Sbjct: 293 QCTCKLGVTGLTCNRCGPGY 312
Score = 65.7 bits (153), Expect = 3e-09
Identities = 45/163 (27%), Positives = 66/163 (40%), Gaps = 17/163 (10%)
Query: 1765 CQCNGHSDQCDVNT-GICLNCADNTIGDHCEFCMSGYHG----DATVGTPRDCLICACPM 1819
CQC+GH+ +C +C +T G CE C + AT P CL C+C
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 1820 -----PYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
+ S F LS +G + C+ G C YC G++ P + + C
Sbjct: 217 HARRCRFNSELFRLSG--GRSGGVCE-RCRHHTAGRHCHYCQPGFWRDPSQ-PIFSRRAC 272
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
+ C C + G+C+ +G C C G CN C PG+
Sbjct: 273 RACQC--HPIGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPGY 312
Score = 64.9 bits (151), Expect = 5e-09
Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 28/145 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G CE C H P C+PC CN H+ +C N+
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNFALSCDLSE 1834
G+C C +T G HC +C G+ D + + + R C C C +P +C+ +
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQC---HPIGATGGTCNQTS 291
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGY 1859
C C+ G G C C GY
Sbjct: 292 G----QCTCKLGVTGLTCNRCGPGY 312
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 24/134 (17%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGLG---CTPCNCGIASESTQCDDD-------- 1991
C CR G C+ C P H W T C PC+C + + + +
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWN------YTKDGCDHCNCNTGYSVGFMCNAT-GQC 2042
G C RC G+ C C GFW +++ C C C+ + G CN T GQC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 2043 ECLPGVIGEKCDRC 2056
C GV G C+RC
Sbjct: 295 TCKLGVTGLTCNRC 308
Score = 63.3 bits (147), Expect = 2e-08
Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLY----WN-LQEYNPFGCEQCNCNLAGT---L 701
A C + C C+ G C C+P + W +P C C+CN
Sbjct: 164 ARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRF 223
Query: 702 NS---LGACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG---CTECDCDIGGSI 754
NS + G C C+ H R C C GF+R + +F C C C G+
Sbjct: 224 NSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT 283
Query: 755 DNNCDKTTGQCHCHSRVEGRRCDQ 778
C++T+GQC C V G C++
Sbjct: 284 GGTCNQTSGQCTCKLGVTGLTCNR 307
Score = 60.1 bits (139), Expect = 1e-07
Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 23/138 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDV------- 512
C C+ +G C C+ + ++P C PC+C+ ++
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 513 -SGQCI-CKAGFGGPRCDQCLSGYYM---QVLGRERQCVPCNCDPTGSTSTSCS-ADGKC 566
G C C+ G C C G++ Q + R C C C P G+T +C+ G+C
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 567 NCLTNFGGAQCDQCSPGY 584
C G C++C PGY
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 58.4 bits (135), Expect = 5e-07
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 31/141 (21%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CDDN--------- 1397
+C C+ + G C +CR + +P C PC C A C N
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1398 ---GMCI-CPKNVEGENCDRCKPYTFNFDVQ-----RGCDDCNCNPLGVVGNQLQCEADS 1448
G+C C + G +C C+P + Q R C C C+P+G G C S
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT--CNQTS 291
Query: 1449 GKCACRENVRGRVCDHCVPGH 1469
G+C C+ V G C+ C PG+
Sbjct: 292 GQCTCKLGVTGLTCNRCGPGY 312
Score = 57.6 bits (133), Expect = 8e-07
Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 22/138 (15%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRG-------CDDCNCNP------LGVVGNQLQCEA 1446
C C + G C+ C+P ++ + C C+CN +L
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1447 DSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYDVCDQNTAQC 1497
G C CR + GR C +C PG + P C C C+ G T C+Q + QC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 1498 YCKTNVRGQACDTCKEEY 1515
CK V G C+ C Y
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 53.6 bits (123), Expect = 1e-05
Identities = 41/173 (23%), Positives = 63/173 (36%), Gaps = 25/173 (14%)
Query: 515 QCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNCDPTGSTSTSCS-------- 561
+C C+ GP C+ C + + R C+PC+C+ S
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 562 -ADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGSTCDD-NGL 610
+ G C C + G C C PG+++ P C +C C G+ G TC+ +G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 611 CHCKSNFDGAKCDTCREQFYNYPACE-ECNCDPRGVTASFAGCGSVPAGELCQ 662
C CK G C+ C + + C P T G+ + CQ
Sbjct: 294 CTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQ 346
Score = 50.4 bits (115), Expect = 1e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 1945 GTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRC 1997
G C CR G C C P W + + C C C I + C+ +GQC C
Sbjct: 237 GVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTC 296
Query: 1998 AKGVTGKQCDQCAAGF 2013
GVTG C++C G+
Sbjct: 297 KLGVTGLTCNRCGPGY 312
Score = 46.0 bits (104), Expect = 0.003
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCR-PC 1386
R C C +G+T CN GQC CK V G TC+ C GY + R PC
Sbjct: 273 RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
Score = 35.1 bits (77), Expect = 4.8
Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 15/86 (17%)
Query: 1439 GNQLQCEADSG--KCACRENVRGRVCDHCVPGHYAFP----------DCYQCTCNRHGTT 1486
G+ +C A + +C CR + G C+ C P H +P C C+CN+H
Sbjct: 161 GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARR 220
Query: 1487 YDVCDQNTAQCYCKTNVRGQACDTCK 1512
C N+ G C+ C+
Sbjct: 221 ---CRFNSELFRLSGGRSGGVCERCR 243
>BC021210-1|AAH21210.2| 350|Homo sapiens LOC126147 protein protein.
Length = 350
Score = 113 bits (271), Expect = 2e-23
Identities = 58/170 (34%), Positives = 81/170 (47%), Gaps = 13/170 (7%)
Query: 229 GRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
GRC C+GHA C A C C+H+T GP C C WR + C
Sbjct: 155 GRCQCHGHAARC-----AARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPC 209
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPY 348
PC+C+ H C ++ E+ RLS GR GG C C+H+T G +C+ C+P ++R
Sbjct: 210 LPCSCNQHARRCRFNSEL--FRLS---GGR--SGGVCERCRHHTAGRHCHYCQPGFWRDP 262
Query: 349 GKRWDELDVCQPCQCDPHFST-GNCEEESGRCECRPEFQPPDCSSCAYGY 397
+ C+ CQC P +T G C + SG+C C+ C+ C GY
Sbjct: 263 SQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 83.8 bits (198), Expect = 1e-14
Identities = 45/156 (28%), Positives = 70/156 (44%), Gaps = 28/156 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNL 410
CQC H + RC CR P C SC + D+P C PC+CN
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 411 NGTEGEHCTP--------TDGLCP-CKYNYAGKSCEICEDGYY-SPE--------CKNCE 452
+ + + G+C C+++ AG+ C C+ G++ P C+ C+
Sbjct: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C+ +G+ C++ +G CTCK +G TCN+C GY
Sbjct: 277 CHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 73.7 bits (173), Expect = 1e-11
Identities = 47/139 (33%), Positives = 65/139 (46%), Gaps = 15/139 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP--EDTDLHTGDYCKPCNCSGN-----INPQ-DPGSCD 1892
C+C+ G CE C + P T H C PC+C+ + N + S
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD--CDSTTGT 1946
G C +C ++TAG C+ C PGF+ D IFS+ C AC C G C+ T+G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 1947 CVCRPGVIGEKCDRCAPDH 1965
C C+ GV G C+RC P +
Sbjct: 294 CTCKLGVTGLTCNRCGPGY 312
Score = 66.9 bits (156), Expect = 1e-09
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 20/140 (14%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG----CGSVP 656
CHC+ + G C++CR ++P C C+C+ F
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 657 AGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFG---CEQCNCNLAGTLNSLGACNTKSG 712
+G +C+ C+ GR C+ C+P +W F C C C+ G G CN SG
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATG--GTCNQTSG 292
Query: 713 QCVCKQHVGERQCDQCLDGF 732
QC CK V C++C G+
Sbjct: 293 QCTCKLGVTGLTCNRCGPGY 312
Score = 65.7 bits (153), Expect = 3e-09
Identities = 45/163 (27%), Positives = 66/163 (40%), Gaps = 17/163 (10%)
Query: 1765 CQCNGHSDQCDVNT-GICLNCADNTIGDHCEFCMSGYHG----DATVGTPRDCLICACPM 1819
CQC+GH+ +C +C +T G CE C + AT P CL C+C
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 1820 -----PYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
+ S F LS +G + C+ G C YC G++ P + + C
Sbjct: 217 HARRCRFNSELFRLSG--GRSGGVCE-RCRHHTAGRHCHYCQPGFWRDPSQ-PIFSRRAC 272
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
+ C C + G+C+ +G C C G CN C PG+
Sbjct: 273 RACQC--HPIGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPGY 312
Score = 64.9 bits (151), Expect = 5e-09
Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 28/145 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G CE C H P C+PC CN H+ +C N+
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNFALSCDLSE 1834
G+C C +T G HC +C G+ D + + + R C C C +P +C+ +
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQC---HPIGATGGTCNQTS 291
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGY 1859
C C+ G G C C GY
Sbjct: 292 G----QCTCKLGVTGLTCNRCGPGY 312
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 24/134 (17%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGLG---CTPCNCGIASESTQCDDD-------- 1991
C CR G C+ C P H W T C PC+C + + + +
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWN------YTKDGCDHCNCNTGYSVGFMCNAT-GQC 2042
G C RC G+ C C GFW +++ C C C+ + G CN T GQC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 2043 ECLPGVIGEKCDRC 2056
C GV G C+RC
Sbjct: 295 TCKLGVTGLTCNRC 308
Score = 63.3 bits (147), Expect = 2e-08
Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLY----WN-LQEYNPFGCEQCNCNLAGT---L 701
A C + C C+ G C C+P + W +P C C+CN
Sbjct: 164 ARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRF 223
Query: 702 NS---LGACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG---CTECDCDIGGSI 754
NS + G C C+ H R C C GF+R + +F C C C G+
Sbjct: 224 NSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT 283
Query: 755 DNNCDKTTGQCHCHSRVEGRRCDQ 778
C++T+GQC C V G C++
Sbjct: 284 GGTCNQTSGQCTCKLGVTGLTCNR 307
Score = 60.1 bits (139), Expect = 1e-07
Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 23/138 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDV------- 512
C C+ +G C C+ + ++P C PC+C+ ++
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 513 -SGQCI-CKAGFGGPRCDQCLSGYYM---QVLGRERQCVPCNCDPTGSTSTSCS-ADGKC 566
G C C+ G C C G++ Q + R C C C P G+T +C+ G+C
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 567 NCLTNFGGAQCDQCSPGY 584
C G C++C PGY
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 58.4 bits (135), Expect = 5e-07
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 31/141 (21%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CDDN--------- 1397
+C C+ + G C +CR + +P C PC C A C N
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1398 ---GMCI-CPKNVEGENCDRCKPYTFNFDVQ-----RGCDDCNCNPLGVVGNQLQCEADS 1448
G+C C + G +C C+P + Q R C C C+P+G G C S
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT--CNQTS 291
Query: 1449 GKCACRENVRGRVCDHCVPGH 1469
G+C C+ V G C+ C PG+
Sbjct: 292 GQCTCKLGVTGLTCNRCGPGY 312
Score = 57.6 bits (133), Expect = 8e-07
Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 22/138 (15%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRG-------CDDCNCNP------LGVVGNQLQCEA 1446
C C + G C+ C+P ++ + C C+CN +L
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1447 DSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYDVCDQNTAQC 1497
G C CR + GR C +C PG + P C C C+ G T C+Q + QC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 1498 YCKTNVRGQACDTCKEEY 1515
CK V G C+ C Y
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 53.2 bits (122), Expect = 2e-05
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 24/135 (17%)
Query: 515 QCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNCDPTGSTSTSCS-------- 561
+C C+ GP C+ C + + R C+PC+C+ S
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 562 -ADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGSTCDD-NGL 610
+ G C C + G C C PG+++ P C +C C G+ G TC+ +G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 611 CHCKSNFDGAKCDTC 625
C CK G C+ C
Sbjct: 294 CTCKLGVTGLTCNRC 308
Score = 50.4 bits (115), Expect = 1e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 1945 GTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRC 1997
G C CR G C C P W + + C C C I + C+ +GQC C
Sbjct: 237 GVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTC 296
Query: 1998 AKGVTGKQCDQCAAGF 2013
GVTG C++C G+
Sbjct: 297 KLGVTGLTCNRCGPGY 312
Score = 46.0 bits (104), Expect = 0.003
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCR-PC 1386
R C C +G+T CN GQC CK V G TC+ C GY + R PC
Sbjct: 273 RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
Score = 35.1 bits (77), Expect = 4.8
Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 15/86 (17%)
Query: 1439 GNQLQCEADSG--KCACRENVRGRVCDHCVPGHYAFP----------DCYQCTCNRHGTT 1486
G+ +C A + +C CR + G C+ C P H +P C C+CN+H
Sbjct: 161 GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARR 220
Query: 1487 YDVCDQNTAQCYCKTNVRGQACDTCK 1512
C N+ G C+ C+
Sbjct: 221 ---CRFNSELFRLSGGRSGGVCERCR 243
>BC018697-1|AAH18697.2| 489|Homo sapiens hypothetical protein
BC018697 protein.
Length = 489
Score = 113 bits (271), Expect = 2e-23
Identities = 58/170 (34%), Positives = 81/170 (47%), Gaps = 13/170 (7%)
Query: 229 GRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
GRC C+GHA C A C C+H+T GP C C WR + C
Sbjct: 155 GRCQCHGHAARC-----AARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPC 209
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPY 348
PC+C+ H C ++ E+ RLS GR GG C C+H+T G +C+ C+P ++R
Sbjct: 210 LPCSCNQHARRCRFNSEL--FRLS---GGR--SGGVCERCRHHTAGRHCHYCQPGFWRDP 262
Query: 349 GKRWDELDVCQPCQCDPHFST-GNCEEESGRCECRPEFQPPDCSSCAYGY 397
+ C+ CQC P +T G C + SG+C C+ C+ C GY
Sbjct: 263 SQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 83.8 bits (198), Expect = 1e-14
Identities = 45/156 (28%), Positives = 70/156 (44%), Gaps = 28/156 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNL 410
CQC H + RC CR P C SC + D+P C PC+CN
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 411 NGTEGEHCTP--------TDGLCP-CKYNYAGKSCEICEDGYY-SPE--------CKNCE 452
+ + + G+C C+++ AG+ C C+ G++ P C+ C+
Sbjct: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C+ +G+ C++ +G CTCK +G TCN+C GY
Sbjct: 277 CHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 73.7 bits (173), Expect = 1e-11
Identities = 47/139 (33%), Positives = 65/139 (46%), Gaps = 15/139 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP--EDTDLHTGDYCKPCNCSGN-----INPQ-DPGSCD 1892
C+C+ G CE C + P T H C PC+C+ + N + S
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD--CDSTTGT 1946
G C +C ++TAG C+ C PGF+ D IFS+ C AC C G C+ T+G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 1947 CVCRPGVIGEKCDRCAPDH 1965
C C+ GV G C+RC P +
Sbjct: 294 CTCKLGVTGLTCNRCGPGY 312
Score = 66.9 bits (156), Expect = 1e-09
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 20/140 (14%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG----CGSVP 656
CHC+ + G C++CR ++P C C+C+ F
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 657 AGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFG---CEQCNCNLAGTLNSLGACNTKSG 712
+G +C+ C+ GR C+ C+P +W F C C C+ G G CN SG
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATG--GTCNQTSG 292
Query: 713 QCVCKQHVGERQCDQCLDGF 732
QC CK V C++C G+
Sbjct: 293 QCTCKLGVTGLTCNRCGPGY 312
Score = 65.7 bits (153), Expect = 3e-09
Identities = 45/163 (27%), Positives = 66/163 (40%), Gaps = 17/163 (10%)
Query: 1765 CQCNGHSDQCDVNT-GICLNCADNTIGDHCEFCMSGYHG----DATVGTPRDCLICACPM 1819
CQC+GH+ +C +C +T G CE C + AT P CL C+C
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 1820 -----PYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
+ S F LS +G + C+ G C YC G++ P + + C
Sbjct: 217 HARRCRFNSELFRLSG--GRSGGVCE-RCRHHTAGRHCHYCQPGFWRDPSQ-PIFSRRAC 272
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
+ C C + G+C+ +G C C G CN C PG+
Sbjct: 273 RACQC--HPIGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPGY 312
Score = 64.9 bits (151), Expect = 5e-09
Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 28/145 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G CE C H P C+PC CN H+ +C N+
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNFALSCDLSE 1834
G+C C +T G HC +C G+ D + + + R C C C +P +C+ +
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQC---HPIGATGGTCNQTS 291
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGY 1859
C C+ G G C C GY
Sbjct: 292 G----QCTCKLGVTGLTCNRCGPGY 312
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 24/134 (17%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGLG---CTPCNCGIASESTQCDDD-------- 1991
C CR G C+ C P H W T C PC+C + + + +
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWN------YTKDGCDHCNCNTGYSVGFMCNAT-GQC 2042
G C RC G+ C C GFW +++ C C C+ + G CN T GQC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 2043 ECLPGVIGEKCDRC 2056
C GV G C+RC
Sbjct: 295 TCKLGVTGLTCNRC 308
Score = 63.3 bits (147), Expect = 2e-08
Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLY----WN-LQEYNPFGCEQCNCNLAGT---L 701
A C + C C+ G C C+P + W +P C C+CN
Sbjct: 164 ARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRF 223
Query: 702 NS---LGACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG---CTECDCDIGGSI 754
NS + G C C+ H R C C GF+R + +F C C C G+
Sbjct: 224 NSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT 283
Query: 755 DNNCDKTTGQCHCHSRVEGRRCDQ 778
C++T+GQC C V G C++
Sbjct: 284 GGTCNQTSGQCTCKLGVTGLTCNR 307
Score = 60.1 bits (139), Expect = 1e-07
Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 23/138 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDV------- 512
C C+ +G C C+ + ++P C PC+C+ ++
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 513 -SGQCI-CKAGFGGPRCDQCLSGYYM---QVLGRERQCVPCNCDPTGSTSTSCS-ADGKC 566
G C C+ G C C G++ Q + R C C C P G+T +C+ G+C
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 567 NCLTNFGGAQCDQCSPGY 584
C G C++C PGY
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 58.4 bits (135), Expect = 5e-07
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 31/141 (21%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CDDN--------- 1397
+C C+ + G C +CR + +P C PC C A C N
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1398 ---GMCI-CPKNVEGENCDRCKPYTFNFDVQ-----RGCDDCNCNPLGVVGNQLQCEADS 1448
G+C C + G +C C+P + Q R C C C+P+G G C S
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT--CNQTS 291
Query: 1449 GKCACRENVRGRVCDHCVPGH 1469
G+C C+ V G C+ C PG+
Sbjct: 292 GQCTCKLGVTGLTCNRCGPGY 312
Score = 57.6 bits (133), Expect = 8e-07
Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 22/138 (15%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRG-------CDDCNCNP------LGVVGNQLQCEA 1446
C C + G C+ C+P ++ + C C+CN +L
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1447 DSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYDVCDQNTAQC 1497
G C CR + GR C +C PG + P C C C+ G T C+Q + QC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 1498 YCKTNVRGQACDTCKEEY 1515
CK V G C+ C Y
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 53.6 bits (123), Expect = 1e-05
Identities = 41/173 (23%), Positives = 63/173 (36%), Gaps = 25/173 (14%)
Query: 515 QCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNCDPTGSTSTSCS-------- 561
+C C+ GP C+ C + + R C+PC+C+ S
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 562 -ADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGSTCDD-NGL 610
+ G C C + G C C PG+++ P C +C C G+ G TC+ +G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 611 CHCKSNFDGAKCDTCREQFYNYPACE-ECNCDPRGVTASFAGCGSVPAGELCQ 662
C CK G C+ C + + C P T G+ + CQ
Sbjct: 294 CTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQ 346
Score = 50.4 bits (115), Expect = 1e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 1945 GTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRC 1997
G C CR G C C P W + + C C C I + C+ +GQC C
Sbjct: 237 GVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTC 296
Query: 1998 AKGVTGKQCDQCAAGF 2013
GVTG C++C G+
Sbjct: 297 KLGVTGLTCNRCGPGY 312
Score = 46.0 bits (104), Expect = 0.003
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCR-PC 1386
R C C +G+T CN GQC CK V G TC+ C GY + R PC
Sbjct: 273 RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
Score = 35.1 bits (77), Expect = 4.8
Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 15/86 (17%)
Query: 1439 GNQLQCEADSG--KCACRENVRGRVCDHCVPGHYAFP----------DCYQCTCNRHGTT 1486
G+ +C A + +C CR + G C+ C P H +P C C+CN+H
Sbjct: 161 GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARR 220
Query: 1487 YDVCDQNTAQCYCKTNVRGQACDTCK 1512
C N+ G C+ C+
Sbjct: 221 ---CRFNSELFRLSGGRSGGVCERCR 243
>BC018654-1|AAH18654.2| 489|Homo sapiens hypothetical protein
BC018697 protein.
Length = 489
Score = 113 bits (271), Expect = 2e-23
Identities = 58/170 (34%), Positives = 81/170 (47%), Gaps = 13/170 (7%)
Query: 229 GRCMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSC 288
GRC C+GHA C A C C+H+T GP C C WR + C
Sbjct: 155 GRCQCHGHAARC-----AARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPC 209
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPY 348
PC+C+ H C ++ E+ RLS GR GG C C+H+T G +C+ C+P ++R
Sbjct: 210 LPCSCNQHARRCRFNSEL--FRLS---GGR--SGGVCERCRHHTAGRHCHYCQPGFWRDP 262
Query: 349 GKRWDELDVCQPCQCDPHFST-GNCEEESGRCECRPEFQPPDCSSCAYGY 397
+ C+ CQC P +T G C + SG+C C+ C+ C GY
Sbjct: 263 SQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 83.8 bits (198), Expect = 1e-14
Identities = 45/156 (28%), Positives = 70/156 (44%), Gaps = 28/156 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP----------NCKPCTCNL 410
CQC H + RC CR P C SC + D+P C PC+CN
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 411 NGTEGEHCTP--------TDGLCP-CKYNYAGKSCEICEDGYY-SPE--------CKNCE 452
+ + + G+C C+++ AG+ C C+ G++ P C+ C+
Sbjct: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C+ +G+ C++ +G CTCK +G TCN+C GY
Sbjct: 277 CHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 73.7 bits (173), Expect = 1e-11
Identities = 47/139 (33%), Positives = 65/139 (46%), Gaps = 15/139 (10%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP--EDTDLHTGDYCKPCNCSGN-----INPQ-DPGSCD 1892
C+C+ G CE C + P T H C PC+C+ + N + S
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACICDEFGMAD--CDSTTGT 1946
G C +C ++TAG C+ C PGF+ D IFS+ C AC C G C+ T+G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 1947 CVCRPGVIGEKCDRCAPDH 1965
C C+ GV G C+RC P +
Sbjct: 294 CTCKLGVTGLTCNRCGPGY 312
Score = 66.9 bits (156), Expect = 1e-09
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 20/140 (14%)
Query: 611 CHCKSNFDGAKCDTCREQFYNYP----------ACEECNCDPRGVTASFAG----CGSVP 656
CHC+ + G C++CR ++P C C+C+ F
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 657 AGELCQ-CKDRVQGRICNDCKPLYWNLQEYNPFG---CEQCNCNLAGTLNSLGACNTKSG 712
+G +C+ C+ GR C+ C+P +W F C C C+ G G CN SG
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATG--GTCNQTSG 292
Query: 713 QCVCKQHVGERQCDQCLDGF 732
QC CK V C++C G+
Sbjct: 293 QCTCKLGVTGLTCNRCGPGY 312
Score = 65.7 bits (153), Expect = 3e-09
Identities = 45/163 (27%), Positives = 66/163 (40%), Gaps = 17/163 (10%)
Query: 1765 CQCNGHSDQCDVNT-GICLNCADNTIGDHCEFCMSGYHG----DATVGTPRDCLICACPM 1819
CQC+GH+ +C +C +T G CE C + AT P CL C+C
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 1820 -----PYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
+ S F LS +G + C+ G C YC G++ P + + C
Sbjct: 217 HARRCRFNSELFRLSG--GRSGGVCE-RCRHHTAGRHCHYCQPGFWRDPSQ-PIFSRRAC 272
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
+ C C + G+C+ +G C C G CN C PG+
Sbjct: 273 RACQC--HPIGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPGY 312
Score = 64.9 bits (151), Expect = 5e-09
Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 28/145 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP--------SGFCVPCQCNGHSDQCDVNT--------- 1778
C C G CE C H P C+PC CN H+ +C N+
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1779 --GICLNCADNTIGDHCEFCMSGYHGDAT--VGTPRDCLICACPMPYPSNNFALSCDLSE 1834
G+C C +T G HC +C G+ D + + + R C C C +P +C+ +
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQC---HPIGATGGTCNQTS 291
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGY 1859
C C+ G G C C GY
Sbjct: 292 G----QCTCKLGVTGLTCNRCGPGY 312
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/134 (30%), Positives = 54/134 (40%), Gaps = 24/134 (17%)
Query: 1947 CVCRPGVIGEKCDRCAPDH----WGLNTGLG---CTPCNCGIASESTQCDDD-------- 1991
C CR G C+ C P H W T C PC+C + + + +
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1992 -NGQC-RCAKGVTGKQCDQCAAGFWN------YTKDGCDHCNCNTGYSVGFMCNAT-GQC 2042
G C RC G+ C C GFW +++ C C C+ + G CN T GQC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 2043 ECLPGVIGEKCDRC 2056
C GV G C+RC
Sbjct: 295 TCKLGVTGLTCNRC 308
Score = 63.3 bits (147), Expect = 2e-08
Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLY----WN-LQEYNPFGCEQCNCNLAGT---L 701
A C + C C+ G C C+P + W +P C C+CN
Sbjct: 164 ARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRF 223
Query: 702 NS---LGACNTKSGQCV-CKQHVGERQCDQCLDGFYRLQTNDVFG---CTECDCDIGGSI 754
NS + G C C+ H R C C GF+R + +F C C C G+
Sbjct: 224 NSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT 283
Query: 755 DNNCDKTTGQCHCHSRVEGRRCDQ 778
C++T+GQC C V G C++
Sbjct: 284 GGTCNQTSGQCTCKLGVTGLTCNR 307
Score = 60.1 bits (139), Expect = 1e-07
Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 23/138 (16%)
Query: 470 CTCKSKYSGRTCNQCQAGYYNYP----------TCKPCNCDTSGTEPSICDDV------- 512
C C+ +G C C+ + ++P C PC+C+ ++
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 513 -SGQCI-CKAGFGGPRCDQCLSGYYM---QVLGRERQCVPCNCDPTGSTSTSCS-ADGKC 566
G C C+ G C C G++ Q + R C C C P G+T +C+ G+C
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 567 NCLTNFGGAQCDQCSPGY 584
C G C++C PGY
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 58.4 bits (135), Expect = 5e-07
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 31/141 (21%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFP----------NCRPCHCPSTAI-CDDN--------- 1397
+C C+ + G C +CR + +P C PC C A C N
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 1398 ---GMCI-CPKNVEGENCDRCKPYTFNFDVQ-----RGCDDCNCNPLGVVGNQLQCEADS 1448
G+C C + G +C C+P + Q R C C C+P+G G C S
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT--CNQTS 291
Query: 1449 GKCACRENVRGRVCDHCVPGH 1469
G+C C+ V G C+ C PG+
Sbjct: 292 GQCTCKLGVTGLTCNRCGPGY 312
Score = 57.6 bits (133), Expect = 8e-07
Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 22/138 (15%)
Query: 1400 CICPKNVEGENCDRCKPYTFNFDVQRG-------CDDCNCNP------LGVVGNQLQCEA 1446
C C + G C+ C+P ++ + C C+CN +L
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1447 DSGKCA-CRENVRGRVCDHCVPGHYAFPD--------CYQCTCNRHGTTYDVCDQNTAQC 1497
G C CR + GR C +C PG + P C C C+ G T C+Q + QC
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 1498 YCKTNVRGQACDTCKEEY 1515
CK V G C+ C Y
Sbjct: 295 TCKLGVTGLTCNRCGPGY 312
Score = 53.6 bits (123), Expect = 1e-05
Identities = 41/173 (23%), Positives = 63/173 (36%), Gaps = 25/173 (14%)
Query: 515 QCICKAGFGGPRCDQCLSGY----YMQVLGRE-RQCVPCNCDPTGSTSTSCS-------- 561
+C C+ GP C+ C + + R C+PC+C+ S
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 562 -ADGKCN-CLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGSTCDD-NGL 610
+ G C C + G C C PG+++ P C +C C G+ G TC+ +G
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 611 CHCKSNFDGAKCDTCREQFYNYPACE-ECNCDPRGVTASFAGCGSVPAGELCQ 662
C CK G C+ C + + C P T G+ + CQ
Sbjct: 294 CTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQ 346
Score = 50.4 bits (115), Expect = 1e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 1945 GTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCRC 1997
G C CR G C C P W + + C C C I + C+ +GQC C
Sbjct: 237 GVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTC 296
Query: 1998 AKGVTGKQCDQCAAGF 2013
GVTG C++C G+
Sbjct: 297 KLGVTGLTCNRCGPGY 312
Score = 46.0 bits (104), Expect = 0.003
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCR-PC 1386
R C C +G+T CN GQC CK V G TC+ C GY + R PC
Sbjct: 273 RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
Score = 35.1 bits (77), Expect = 4.8
Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 15/86 (17%)
Query: 1439 GNQLQCEADSG--KCACRENVRGRVCDHCVPGHYAFP----------DCYQCTCNRHGTT 1486
G+ +C A + +C CR + G C+ C P H +P C C+CN+H
Sbjct: 161 GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARR 220
Query: 1487 YDVCDQNTAQCYCKTNVRGQACDTCK 1512
C N+ G C+ C+
Sbjct: 221 ---CRFNSELFRLSGGRSGGVCERCR 243
>AK024691-1|BAB14964.1| 341|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21038 fis, clone CAE10631. ).
Length = 341
Score = 110 bits (265), Expect = 8e-23
Identities = 53/166 (31%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRF--SCEPCNCHNHTTECTYDPEIDEKRL 311
C C+HNT G C C + + W + C C C+ H C +D + E
Sbjct: 6 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA-- 63
Query: 312 SLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST-- 369
+G GG C +CQHNTEG C +C+P +YR + + D C+PC C P S
Sbjct: 64 ----SGN-RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVL 118
Query: 370 -GN----CEEESGRCECRPEFQPPDCSSCAYGYFDYPN--CKPCTC 408
N C+ +G C C+P C C GY+ + + C+PC C
Sbjct: 119 PANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 164
Score = 99.5 bits (237), Expect = 2e-19
Identities = 61/176 (34%), Positives = 78/176 (44%), Gaps = 27/176 (15%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP-EDTDLHTG--DYCKPCNCSGNINPQD------PGSC 1891
C C+ G+ C++CA Y P E D TG + C+ C C+G+ + S
Sbjct: 6 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 65
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAI--FSKN--CTACICDEFGMAD-------- 1939
+ G C C +NT G C C PGFY D FS C C C G A
Sbjct: 66 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 125
Query: 1940 CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC 1995
CD + G C C+PGV G +CDRC +WG GC PC+C + CD G C
Sbjct: 126 CDPSNGDCPCKPGVAGRRCDRCMVGYWGFG-DYGCRPCDC-----AGSCDPITGDC 175
Score = 95.9 bits (228), Expect = 2e-18
Identities = 68/188 (36%), Positives = 90/188 (47%), Gaps = 42/188 (22%)
Query: 1731 TSVEECQ-CPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC--DVNT--------- 1778
T+ CQ C Y E A+G P+ C C+CNGH+D C DVN
Sbjct: 12 TAGSHCQHCAPLYNDRPWE-AADGKTGAPNE-CRTCKCNGHADTCHFDVNVWEASGNRSG 69
Query: 1779 GICLNCADNTIGDHCEFCMSGYHGD--ATVGTPRDCLICAC-PM---PYPSNNFALSCDL 1832
G+C +C NT G +C+ C G++ D P C C+C P+ P+N+ CD
Sbjct: 70 GVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF-CDP 128
Query: 1833 SENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDY-CKPCNCSGNINPQDPGSC 1891
S NG C C+PG G RC+ C GY+G GDY C+PC+C+ GSC
Sbjct: 129 S-NG---DCPCKPGVAGRRCDRCMVGYWGF--------GDYGCRPCDCA--------GSC 168
Query: 1892 DSINGDCL 1899
D I GDC+
Sbjct: 169 DPITGDCI 176
Score = 82.6 bits (195), Expect = 2e-14
Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 33/182 (18%)
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYP------------ACEECNCDPRGVTASF-----A 650
+G C CK N G+ C C + + P C C C+ T F
Sbjct: 3 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE 62
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP-LYWNLQE--YNPFGCEQCNCNLAGTL----NS 703
G+ G C+ +G+ C CKP Y +L+ P C+ C+C+ G+ NS
Sbjct: 63 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 122
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
+ C+ +G C CK V R+CD+C+ G++ +GC CDC GS CD TG
Sbjct: 123 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDC--AGS----CDPITG 173
Query: 764 QC 765
C
Sbjct: 174 DC 175
Score = 80.2 bits (189), Expect = 1e-13
Identities = 55/180 (30%), Positives = 79/180 (43%), Gaps = 46/180 (25%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYP------------NCKPCTCN---------LNGTEG 415
G+C C+ C CA Y D P C+ C CN +N E
Sbjct: 4 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 63
Query: 416 EHCTPTDGLCP-CKYNYAGKSCEICEDGYY--------SPE-CKNCECNTVGSVSY---- 461
+ G+C C++N G+ C+ C+ G+Y +P+ CK C C+ VGS
Sbjct: 64 SG-NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 122
Query: 462 --VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQCI 517
CD GDC CK +GR C++C GY+ + C+PC+C S CD ++G CI
Sbjct: 123 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGS------CDPITGDCI 176
Score = 77.8 bits (183), Expect = 7e-13
Identities = 50/165 (30%), Positives = 72/165 (43%), Gaps = 34/165 (20%)
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFS---------KNCTACICD------EFGM- 1937
++G C+ C +NTAG+ C CAP Y D + C C C+ F +
Sbjct: 2 VHGKCM-CKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVN 59
Query: 1938 ---ADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCGI------- 1981
A + + G C C+ G+ C RC P + + C PC+C
Sbjct: 60 VWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLP 119
Query: 1982 ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNC 2026
A+ T CD NG C C GV G++CD+C G+W + GC C+C
Sbjct: 120 ANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 164
Score = 77.0 bits (181), Expect = 1e-12
Identities = 58/177 (32%), Positives = 75/177 (42%), Gaps = 41/177 (23%)
Query: 1357 GQCPCKPNVIGRTCSAC-----------RTGYYGFPN-CRPCHC---PSTAICDDN---- 1397
G+C CK N G C C G G PN CR C C T D N
Sbjct: 4 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 63
Query: 1398 ------GMC-ICPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLG---VVGNQL 1442
G+C C N EG+ C RCKP + F C C+C+P+G + N +
Sbjct: 64 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 123
Query: 1443 Q-CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTYDVCDQNTAQC 1497
C+ +G C C+ V GR CD C+ G++ F D Y C C+ G+ CD T C
Sbjct: 124 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD-YGCRPCDCAGS----CDPITGDC 175
Score = 71.7 bits (168), Expect = 5e-11
Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 39/164 (23%)
Query: 423 GLCPCKYNYAGKSCEICEDGYY------------SP-ECKNCECNTVGSVSYVC------ 463
G C CK+N AG C+ C Y +P EC+ C+CN +
Sbjct: 4 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 63
Query: 464 --DKLTGDCT-CKSKYSGRTCNQCQAGYY-------NYP-TCKPCNCDTSGT------EP 506
++ G C C+ G+ C +C+ G+Y + P CKPC+C G+
Sbjct: 64 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 123
Query: 507 SICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
+ CD +G C CK G G RCD+C+ GY+ G + C PC+C
Sbjct: 124 TFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFG-DYGCRPCDC 164
Score = 70.9 bits (166), Expect = 8e-11
Identities = 54/184 (29%), Positives = 75/184 (40%), Gaps = 43/184 (23%)
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYP------------DCLSCNC---------DVSGSIG 602
GKC C N G+ C C+P Y P +C +C C DV+
Sbjct: 4 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 63
Query: 603 STCDDNGLC-HCKSNFDGAKCDTCREQFY-------NYP-ACEECNCDPRGVTASFAGCG 653
S G+C C+ N +G C C+ FY + P AC+ C+C P G A
Sbjct: 64 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 123
Query: 654 SV--PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS 711
+ P+ C CK V GR C+ C YW +Y GC C+C G+C+ +
Sbjct: 124 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDC--------AGSCDPIT 172
Query: 712 GQCV 715
G C+
Sbjct: 173 GDCI 176
Score = 67.3 bits (157), Expect = 1e-09
Identities = 56/195 (28%), Positives = 75/195 (38%), Gaps = 37/195 (18%)
Query: 1397 NGMCICPKNVEGENCDRCKPYTFN-----FDVQRG----CDDCNCNP------LGVVGNQ 1441
+G C+C N G +C C P + D + G C C CN V +
Sbjct: 3 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE 62
Query: 1442 LQCEADSGKCA-CRENVRGRVCDHCVPGHY-------AFPD-CYQCTCNRHGT------T 1486
G C C+ N G+ C C PG Y + PD C C+C+ G+ +
Sbjct: 63 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 122
Query: 1487 YDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGK----TTRCSSSY 1542
CD + C CK V G+ CD C Y+ D GC C C G T C SS+
Sbjct: 123 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDCAGSCDPITGDCISSH 179
Query: 1543 YTWAAIDEMVDWYPV 1557
E+ D+ PV
Sbjct: 180 TDIDWYHEVPDFRPV 194
Score = 63.7 bits (148), Expect = 1e-08
Identities = 34/73 (46%), Positives = 39/73 (53%), Gaps = 11/73 (15%)
Query: 1338 RPCLCDFMGSTELECN--TF----GGQCPCKPNVIGRTCSACRTGYYGFPN--CRPCHCP 1389
+PC C +GS L N TF G CPCKP V GR C C GY+GF + CRPC C
Sbjct: 106 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCA 165
Query: 1390 STAICDD-NGMCI 1401
+ CD G CI
Sbjct: 166 GS--CDPITGDCI 176
Score = 61.3 bits (142), Expect = 6e-08
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 32/160 (20%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDH----WGLNTGLG-----CTPCNCGIASESTQCDDD---- 1991
G C+C+ G C CAP + W G C C C +++ D +
Sbjct: 4 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 63
Query: 1992 -----NGQCR-CAKGVTGKQCDQCAAGFWNYTK------DGCDHCNCNT-------GYSV 2032
G C C G+ C +C GF+ + D C C+C+ SV
Sbjct: 64 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 123
Query: 2033 GFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECD 2072
F + G C C PGV G +CDRC + GC CD
Sbjct: 124 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCD 163
Score = 60.5 bits (140), Expect = 1e-07
Identities = 48/156 (30%), Positives = 66/156 (42%), Gaps = 32/156 (20%)
Query: 231 CMCNGHADTC----EPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
C CNGHADTC + +GN + VC CQHNT G C +C GF + R D
Sbjct: 45 CKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPD- 103
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY- 344
+C+PC+CH P + + G C C+ G C++C Y
Sbjct: 104 -ACKPCSCH---------PVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYW 152
Query: 345 -YRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC 379
+ YG C+PC C G+C+ +G C
Sbjct: 153 GFGDYG--------CRPCDC-----AGSCDPITGDC 175
Score = 60.1 bits (139), Expect = 1e-07
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 34/163 (20%)
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQ-------VLGRERQCVPCNCDPTGST-------- 556
V G+C+CK G C C Y + G +C C C+ T
Sbjct: 2 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 61
Query: 557 -STSCSADGKC-NCLTNFGGAQCDQCSPGYYK-------YPD-CLSCNCDVSGSI----- 601
++ + G C +C N G C +C PG+Y+ PD C C+C GS
Sbjct: 62 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 121
Query: 602 -GSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYP--ACEECNC 640
+ CD NG C CK G +CD C ++ + C C+C
Sbjct: 122 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 164
Score = 59.3 bits (137), Expect = 3e-07
Identities = 49/141 (34%), Positives = 56/141 (39%), Gaps = 23/141 (16%)
Query: 661 CQCKDRVQGRICNDCKPLY----WNLQEYN---PFGCEQCNCN-LAGT----LNSLGACN 708
C CK G C C PLY W + P C C CN A T +N A
Sbjct: 6 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 65
Query: 709 TKSGQ-CVCKQHVGERQ-CDQCLDGFYRLQTNDVFG---CTECDCDIGGS--IDNN---- 757
+SG C QH E Q C +C GFYR C C C GS + N
Sbjct: 66 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 125
Query: 758 CDKTTGQCHCHSRVEGRRCDQ 778
CD + G C C V GRRCD+
Sbjct: 126 CDPSNGDCPCKPGVAGRRCDR 146
Score = 38.3 bits (85), Expect = 0.52
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN 1783
+C C G C++C G++ C PC C G CD TG C++
Sbjct: 132 DCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG---SCDPITGDCIS 177
>AB052951-1|BAC53753.1| 866|Homo sapiens SRECRP-1 protein.
Length = 866
Score = 110 bits (265), Expect = 8e-23
Identities = 117/426 (27%), Positives = 157/426 (36%), Gaps = 77/426 (18%)
Query: 377 GRCECR-PEFQPPDCSSCAYGYFDYPNCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAG 433
GR CR P Q P C CA C C N T E E C G C C++ Y G
Sbjct: 50 GRNVCRAPGSQVPTC--CAGWRQQGDECGIAVCEGNSTCSENEVCV-RPGECRCRHGYFG 106
Query: 434 KSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN---QCQAGY 488
+C+ C ++ P+CK C C+ G C+ +TG CTC ++ G C QCQ G
Sbjct: 107 ANCDTKCPRQFWGPDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHGT 162
Query: 489 YNYPTCKPCNCDTS--GTE---------PSICDDVSGQCICKAGFGGPRCDQ---CLSGY 534
+P C C++ G + S CD +G C+C AG+ G C+ C S
Sbjct: 163 C-HPRSGACRCESGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSP 221
Query: 535 YMQVLGR---ERQCVPCNCDPTGSTSTS-CS-ADGKCNCLTNFGGAQC-DQCSPGYYKYP 588
Q GR + CD C DG C C + G C + C G+Y
Sbjct: 222 CEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLG 281
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRG--- 644
C G T + C+ ++G KCD C FY C G
Sbjct: 282 CRRRCG-QCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHAC 340
Query: 645 --VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
VT C + G+ C+ K G DC F C C
Sbjct: 341 NHVTGKCTRCNAGWIGDRCETKCS-NGTYGEDCA-----------FVCADCGS------- 381
Query: 703 SLGACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDK 760
G C+ +SG+C+C V C+ C G + C + C C ++ CD
Sbjct: 382 --GHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD------CAQACSCH-----EDTCDP 428
Query: 761 TTGQCH 766
TG CH
Sbjct: 429 VTGACH 434
Score = 97.1 bits (231), Expect = 1e-18
Identities = 103/388 (26%), Positives = 145/388 (37%), Gaps = 72/388 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC+H G C+ C Q W E C+CH H +C ++
Sbjct: 98 CRCRHGYFGANCDTKCP---------RQFWGPDCKELCSCHPHG-QC------EDVTGQC 141
Query: 314 DINGRYEGGGKC---LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG 370
+ R G +C CQH T CR W C C +T
Sbjct: 142 TCHAR-RWGARCEHACQCQHGTCHPRSGACRCE------SGWWGAQCASACYCS---ATS 191
Query: 371 NCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKP-CTCNLN--GTEGEH--------C 418
C+ ++G C C + C++ CA C C G + C
Sbjct: 192 RCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRC 251
Query: 419 TPTDGLCPCKYNYAGKSC-EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDC-TCKSKY 476
P DG C C+ Y GK C E C G+Y C+ C C G C TC+ +
Sbjct: 252 HPVDGTCACEPGYRGKYCREPCPAGFYGLGCRR-RCGQCKG-QQPCTVAEGRCLTCEPGW 309
Query: 477 SGRTCNQ-CQAGYYN---YPTCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD-QC 530
+G C+Q C G+Y C PC + C+ V+G+C C AG+ G RC+ +C
Sbjct: 310 NGTKCDQPCATGFYGEGCSHRCPPCR------DGHACNHVTGKCTRCNAGWIGDRCETKC 363
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPD 589
+G Y G + V +C GS + G+C C G C+ C PG +
Sbjct: 364 SNGTY----GEDCAFVCADC---GSGHCDFQS-GRCLCSPGVHGPHCNVTCPPGLHGADC 415
Query: 590 CLSCNCDVSGSIGSTCDD-NGLCHCKSN 616
+C+C TCD G CH ++N
Sbjct: 416 AQACSCH-----EDTCDPVTGACHLETN 438
Score = 94.3 bits (224), Expect = 7e-18
Identities = 100/344 (29%), Positives = 133/344 (38%), Gaps = 54/344 (15%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVP-CQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC+C Y G +C+ + P C C C+ H QC+ TG C C G C
Sbjct: 97 ECRCRHGYFGANCDTKCPRQFWGPD--CKELCSCHPHG-QCEDVTGQC-TCHARRWGARC 152
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENG----SLISCNCQPGYGG 1849
E HG PR C C + A +C S +C C G+ G
Sbjct: 153 EHACQCQHGTC---HPRSG-ACRCESGWWGAQCASACYCSATSRCDPQTGACLCHAGWWG 208
Query: 1850 ARC-EYCAAG------YYGIPEDTDLHTGDYC-KPCNCSGNINPQDPGSCDSINGDCLKC 1901
C CA G + + G C + C C G C ++G C C
Sbjct: 209 RSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCF-------RGRCHPVDGTC-AC 260
Query: 1902 VNNTAGAAC-NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
G C C GFYG + C C G C G C+ C PG G KCD
Sbjct: 261 EPGYRGKYCREPCPAGFYGLGC-RRRCGQC----KGQQPCTVAEGRCLTCEPGWNGTKCD 315
Query: 1960 R-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGVTGKQCD-QCAAGFWNY 2016
+ CA +G C PC G A C+ G+C RC G G +C+ +C+ G Y
Sbjct: 316 QPCATGFYGEGCSHRCPPCRDGHA-----CNHVTGKCTRCNAGWIGDRCETKCSNG--TY 368
Query: 2017 TKDGCDHC-NCNTGYSVGFMCN-ATGQCECLPGVIGEKCD-RCP 2057
+D C +C +G+ C+ +G+C C PGV G C+ CP
Sbjct: 369 GEDCAFVCADCGSGH-----CDFQSGRCLCSPGVHGPHCNVTCP 407
Score = 93.1 bits (221), Expect = 2e-17
Identities = 104/355 (29%), Positives = 150/355 (42%), Gaps = 59/355 (16%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKP-CNCDTSGTEPSI 508
CE N+ S + VC + G+C C+ Y G C+ +C ++ P CK C+C G
Sbjct: 80 CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQ---- 133
Query: 509 CDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS---CSADGK 565
C+DV+GQC C A G RC+ + R C C G+ S CSA +
Sbjct: 134 CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGAC-RCESGWWGAQCASACYCSATSR 192
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDT 624
C+ T GA C C G++ C C+ S C+ +G C C+ GA+CD
Sbjct: 193 CDPQT---GA-C-LCHAGWWGRSCNNQCACN-----SSPCEQQSGRCQCRERTFGARCDR 242
Query: 625 CREQFYN--YPACEECNCDP--RG------VTASFAGCGSVPAGELCQCKDR-----VQG 669
+ F +P C C+P RG A F G G QCK + +G
Sbjct: 243 YCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGC--RRRCGQCKGQQPCTVAEG 300
Query: 670 RICNDCKPLYWNLQEYNP-----FGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQ-HVGE 722
R C C+P WN + + F E C+ + ACN +G+C C +G+
Sbjct: 301 R-CLTCEP-GWNGTKCDQPCATGFYGEGCS-HRCPPCRDGHACNHVTGKCTRCNAGWIGD 357
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R +C +G Y + F C +C GS +CD +G+C C V G C+
Sbjct: 358 RCETKCSNGTY--GEDCAFVCADC-----GS--GHCDFQSGRCLCSPGVHGPHCN 403
Score = 91.5 bits (217), Expect = 5e-17
Identities = 107/410 (26%), Positives = 151/410 (36%), Gaps = 70/410 (17%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP 401
PT + ++ DE + C+ + S G C CR + +C + F P
Sbjct: 62 PTCCAGWRQQGDECGIAV-CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP 120
Query: 402 NCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE---ICEDGYYSPECKNCECNT-- 455
+CK C+C+ +G C G C C G CE C+ G P C C +
Sbjct: 121 DCKELCSCHPHG----QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCESGW 176
Query: 456 ----VGSVSYV-----CDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKP----CNC-- 499
S Y CD TG C C + + GR+C NQC N C+ C C
Sbjct: 177 WGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCAC---NSSPCEQQSGRCQCRE 233
Query: 500 DTSGTE--------PSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNC 550
T G C V G C C+ G+ G C + C +G+Y LG R+C C
Sbjct: 234 RTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFY--GLGCRRRCGQCK- 290
Query: 551 DPTGSTSTSCSADGKC-NCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD- 607
A+G+C C + G +CDQ C+ G+ Y + S C G C+
Sbjct: 291 ----GQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF--YGEGCSHRCPPCRD-GHACNHV 343
Query: 608 NGLC-HCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFAGCGSVP-AGELCQCK 664
G C C + + G +C+T C Y E+C + G G C C
Sbjct: 344 TGKCTRCNAGWIGDRCETKCSNGTYG----EDC-----AFVCADCGSGHCDFQSGRCLCS 394
Query: 665 DRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
V G CN C P C + C+ GAC+ ++ Q
Sbjct: 395 PGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPV-----TGACHLETNQ 439
Score = 89.0 bits (211), Expect = 3e-16
Identities = 64/193 (33%), Positives = 86/193 (44%), Gaps = 32/193 (16%)
Query: 1840 SCNCQPGYGGARC-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
+C C+PGY G C E C AG+YG+ C+ C G Q P C G C
Sbjct: 257 TCACEPGYRGKYCREPCPAGFYGLG----------CRR-RC-GQCKGQQP--CTVAEGRC 302
Query: 1899 LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGE 1956
L C G C+ CA GFYG+ S C C G A C+ TG C C G IG+
Sbjct: 303 LTCEPGWNGTKCDQPCATGFYGEGC-SHRCPPC---RDGHA-CNHVTGKCTRCNAGWIGD 357
Query: 1957 KCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFW 2014
+C+ +C+ +G + C C G CD +G+C C+ GV G C+ C G
Sbjct: 358 RCETKCSNGTYGEDCAFVCADCGSG------HCDFQSGRCLCSPGVHGPHCNVTCPPGL- 410
Query: 2015 NYTKDGCDHCNCN 2027
+ D C+C+
Sbjct: 411 -HGADCAQACSCH 422
Score = 84.6 bits (200), Expect = 6e-15
Identities = 77/247 (31%), Positives = 106/247 (42%), Gaps = 53/247 (21%)
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHC-EFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CQC +C G C C G +C E C +G++G +G R C C P
Sbjct: 244 CQC--FRGRCHPVDGTCA-CEPGYRGKYCREPCPAGFYG---LGCRRRCGQCKGQQP--- 294
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGN 1882
C ++E L C+PG+ G +C+ CA G+YG + H C PC
Sbjct: 295 ------CTVAEGRCL---TCEPGWNGTKCDQPCATGFYG---EGCSHR---CPPC----- 334
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCD 1941
+D +C+ + G C +C G C C+ G YG+ +C A +C + G CD
Sbjct: 335 ---RDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGE-----DC-AFVCADCGSGHCD 385
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRC--- 1997
+G C+C PGV G C+ P GL+ G C C+C E T CD G C
Sbjct: 386 FQSGRCLCSPGVHGPHCNVTCPP--GLH-GADCAQACSC---HEDT-CDPVTGACHLETN 438
Query: 1998 -AKGVTG 2003
KGV G
Sbjct: 439 QRKGVMG 445
Score = 76.6 bits (180), Expect = 2e-12
Identities = 78/291 (26%), Positives = 108/291 (37%), Gaps = 36/291 (12%)
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFG 573
G+ +C+A G + C +G+ Q G E C + T S + C G+C C +
Sbjct: 50 GRNVCRAP--GSQVPTCCAGWRQQ--GDECGIAVCEGNSTCSENEVCVRPGECRCRHGYF 105
Query: 574 GAQCDQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFY 630
GA CD P + PDC C+C G C+D G C C + GA+C+ C+ Q
Sbjct: 106 GANCDTKCPRQFWGPDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHG 161
Query: 631 N-YPACEECNCDP---RGVTASFAGCGSV----PAGELCQCKDRVQGRICNDCKPLYWNL 682
+P C C+ AS C + P C C GR CN+ +
Sbjct: 162 TCHPRSGACRCESGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSP 221
Query: 683 QEYNPFGCEQCNCNLAGTLNS------LGACNTKSGQCVCKQHVGERQC-DQCLDGFYRL 735
E C QC G G C+ G C C+ + C + C GFY L
Sbjct: 222 CEQQSGRC-QCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL 280
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGRRCDQPIRAHYF 785
GC G C G+C C G +CDQP ++
Sbjct: 281 ------GCRRRCGQCKG--QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/162 (31%), Positives = 66/162 (40%), Gaps = 25/162 (15%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSA-CRTGYYG---FPNCRPCHCPSTAICDDNGMCI-CPKN 1405
C G+C C+P G C C TG+YG C PC A G C C
Sbjct: 295 CTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCR-DGHACNHVTGKCTRCNAG 353
Query: 1406 VEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD- 1463
G+ C+ +C T+ D C DC C+ SG+C C V G C+
Sbjct: 354 WIGDRCETKCSNGTYGEDCAFVCADCGSG---------HCDFQSGRCLCSPGVHGPHCNV 404
Query: 1464 HCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
C PG + DC Q C+C+ D CD T C+ +TN R
Sbjct: 405 TCPPGLHG-ADCAQACSCHE-----DTCDPVTGACHLETNQR 440
Score = 60.9 bits (141), Expect = 8e-08
Identities = 64/247 (25%), Positives = 96/247 (38%), Gaps = 53/247 (21%)
Query: 1841 CNCQPGYGGARCEY-CAAGYYGIPEDTDL---HTGDYCKP----CNCSGNI-NPQDPGSC 1891
C C+ GY GA C+ C ++G P+ +L H C+ C C + +C
Sbjct: 98 CRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHAC 156
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRP 1951
+G C + AC C G++G ++ +AC C + CD TG C+C
Sbjct: 157 QCQHGTC-----HPRSGACR-CESGWWG----AQCASACYCS--ATSRCDPQTGACLCHA 204
Query: 1952 GVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G G C+ +CA CN S+ C+ +G+C+C + G +CD+
Sbjct: 205 GWWGRSCNNQCA--------------CN------SSPCEQQSGRCQCRERTFGARCDRYC 244
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG----EKCDRCPERWVLIPQE 2066
F C C GY G C C G G +C +C + E
Sbjct: 245 QCFRGRCHPVDGTCACEPGYR-GKYCRE----PCPAGFYGLGCRRRCGQCKGQQPCTVAE 299
Query: 2067 G-CLECD 2072
G CL C+
Sbjct: 300 GRCLTCE 306
Score = 57.6 bits (133), Expect = 8e-07
Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 28/197 (14%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC-SACRTGYYGF 1380
CRE F + R C C F G C+ G C C+P G+ C C G+YG
Sbjct: 231 CRERTFGARCD-----RYCQC-FRG----RCHPVDGTCACEPGYRGKYCREPCPAGFYGL 280
Query: 1381 PNCRPC-HCPSTAICD-DNGMCI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
R C C C G C+ C G CD+ P F GC C P
Sbjct: 281 GCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQ--PCATGF-YGEGCSH-RCPPCR- 335
Query: 1438 VGNQLQCEADSGKCA-CRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTA 1495
+ C +GKC C G C+ C G Y DC C G+ + CD +
Sbjct: 336 --DGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYG-EDC-AFVCADCGSGH--CDFQSG 389
Query: 1496 QCYCKTNVRGQACD-TC 1511
+C C V G C+ TC
Sbjct: 390 RCLCSPGVHGPHCNVTC 406
Score = 56.0 bits (129), Expect = 2e-06
Identities = 40/164 (24%), Positives = 59/164 (35%), Gaps = 29/164 (17%)
Query: 1357 GQCPCKPNVIGRTCSA-CRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEGENCDR 1413
G+C C+ G C C ++G P+C+ C C C+D G C C G C+
Sbjct: 96 GECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEH 154
Query: 1414 --------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
C P + + G C +C+ +G C C GR C++
Sbjct: 155 ACQCQHGTCHPRSGACRCESGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNN- 213
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
QC CN C+Q + +C C+ G CD
Sbjct: 214 -----------QCACNS-----SPCEQQSGRCQCRERTFGARCD 241
Score = 49.6 bits (113), Expect = 2e-04
Identities = 45/167 (26%), Positives = 62/167 (37%), Gaps = 21/167 (12%)
Query: 1388 CPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
C +C G C C G NCD +C + D + + C+C+P G QCE
Sbjct: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK---ELCSCHPHG------QCED 136
Query: 1447 DSGKCACRENVRGRVCDH-CVPGH-YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G+C C G C+H C H P C C G C + CYC R
Sbjct: 137 VTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRC-ESGWWGAQC---ASACYCSATSR 192
Query: 1505 GQ----ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAA 1547
AC C ++ +N C C ++ RC T+ A
Sbjct: 193 CDPQTGAC-LCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGA 238
Score = 48.0 bits (109), Expect = 6e-04
Identities = 63/226 (27%), Positives = 84/226 (37%), Gaps = 67/226 (29%)
Query: 574 GAQCDQCSPGYYKYPDCLSCNCDVSGSIG-STCDDN------GLCHCKSNFDGAKCDT-C 625
G+Q C G+ + D C ++ G STC +N G C C+ + GA CDT C
Sbjct: 58 GSQVPTCCAGWRQQGD----ECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKC 113
Query: 626 REQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEY 685
QF+ P C+E C P G QC+D V G+ C C W +
Sbjct: 114 PRQFWG-PDCKEL-------------CSCHPHG---QCED-VTGQ-CT-CHARRWGAR-- 151
Query: 686 NPFGCEQ-CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCT 744
CE C C G C+ +SG C C+ QC +
Sbjct: 152 ----CEHACQCQH-------GTCHPRSGACRCESGWWGAQC-----------------AS 183
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAHYFPTLHQ 790
C C S + CD TG C CH+ GR C+ + P Q
Sbjct: 184 ACYC----SATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQ 225
Score = 48.0 bits (109), Expect = 6e-04
Identities = 34/109 (31%), Positives = 48/109 (44%), Gaps = 20/109 (18%)
Query: 1945 GTCVCRPGVIGEKCD-RCAPDHWGLNTGLGCTP-CNCGIASESTQCDDDNGQCRCAKGVT 2002
G C CR G G CD +C WG + C C+C QC+D GQC C
Sbjct: 96 GECRCRHGYFGANCDTKCPRQFWGPD----CKELCSC---HPHGQCEDVTGQCTCHARRW 148
Query: 2003 GKQCD---QCAAGFWNYTKDGCDHCNCNTGY-----SVGFMCNATGQCE 2043
G +C+ QC G + + G C C +G+ + C+AT +C+
Sbjct: 149 GARCEHACQCQHGTC-HPRSGA--CRCESGWWGAQCASACYCSATSRCD 194
Score = 48.0 bits (109), Expect = 6e-04
Identities = 54/210 (25%), Positives = 79/210 (37%), Gaps = 31/210 (14%)
Query: 227 IGGRCMCN-GHADT-CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
+ G C C G+ C PAG L CR + C Q + C+ E + W+
Sbjct: 254 VDGTCACEPGYRGKYCREPCPAGFYG-LGCRRRCGQCKGQ--QPCTVAEGRCLTCEPGWN 310
Query: 285 RFSCE-PCNCHNHTTECTYD-PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN-KCR 341
C+ PC + C++ P + + G KC C G C KC
Sbjct: 311 GTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTG------KCTRCNAGWIGDRCETKCS 364
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDY 400
YG+ D VC C +G+C+ +SGRC C P P C+ +C G
Sbjct: 365 NG---TYGE--DCAFVCADC------GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGA 413
Query: 401 PNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+ C+C+ + C P G C + N
Sbjct: 414 DCAQACSCH-----EDTCDPVTGACHLETN 438
Score = 45.2 bits (102), Expect = 0.005
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 13/105 (12%)
Query: 1977 CNCGIASESTQCDDDN-----GQCRCAKGVTGKQCD-QCAAGFWNYTKDGCDHCNCNTGY 2030
C + ++ C ++ G+CRC G G CD +C FW D + C+C +
Sbjct: 75 CGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWG--PDCKELCSC---H 129
Query: 2031 SVGFMCNATGQCECLPGVIGEKCDR-CP-ERWVLIPQEGCLECDS 2073
G + TGQC C G +C+ C + P+ G C+S
Sbjct: 130 PHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCES 174
Score = 42.3 bits (95), Expect = 0.032
Identities = 56/232 (24%), Positives = 75/232 (32%), Gaps = 41/232 (17%)
Query: 1346 GSTELECNTFGGQCP--CKPNVIGRT-----CSACRTGYYGFPNCRPCHCPSTAICDDNG 1398
G+ E +G QC C + R C G++G C C S+ +G
Sbjct: 168 GACRCESGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSG 227
Query: 1399 MCICPKNVEGENCD--------RCKPYTFNFDVQRGCDDCNCN---PLGVVG-------- 1439
C C + G CD RC P + G C P G G
Sbjct: 228 RCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCG 287
Query: 1440 ---NQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNT 1494
Q C G+C C G CD C G Y ++C R G C+ T
Sbjct: 288 QCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDG---HACNHVT 344
Query: 1495 AQC-YCKTNVRGQACDT-CKEEYFNLQDDNPDGCTKC---FCFGKTTRCSSS 1541
+C C G C+T C + +D C C C ++ RC S
Sbjct: 345 GKCTRCNAGWIGDRCETKCSNGTYG--EDCAFVCADCGSGHCDFQSGRCLCS 394
Score = 39.5 bits (88), Expect = 0.22
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNC--NTGYSVGFMCNATGQCECLPGVIGEKCD-RCPER 2059
G Q C AG W D C C N+ S +C G+C C G G CD +CP +
Sbjct: 58 GSQVPTCCAG-WRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQ 116
Query: 2060 W 2060
+
Sbjct: 117 F 117
>Z99289-8|CAI42333.1| 117|Homo sapiens laminin, alpha 4 protein.
Length = 117
Score = 109 bits (263), Expect = 1e-22
Identities = 47/105 (44%), Positives = 65/105 (61%), Gaps = 3/105 (2%)
Query: 1749 QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGT 1808
+C G + SG CVPC CNG+S++C +G C++C NT G+HCE C+ GY GD+ G
Sbjct: 1 KCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGA 60
Query: 1809 PRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
P+ C C CP+P+ + NFA SC +NG+ + C C Y G CE
Sbjct: 61 PQFCQPCPCPLPHLA-NFAESC-YRKNGA-VRCICNENYAGPNCE 102
Score = 60.5 bits (140), Expect = 1e-07
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 483 QCQAGYYNYPT--CKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCDQCLSGYY-MQV 538
+C AG+++ + C PC+C+ + E C D SG C+ C+ G C++CL GY +
Sbjct: 1 KCNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 57
Query: 539 LGRERQCVPCNC--DPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSP 582
G + C PC C + + SC + +C C N+ G C++ SP
Sbjct: 58 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERPSP 106
Score = 56.4 bits (130), Expect = 2e-06
Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 13/98 (13%)
Query: 1874 CKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACI 1931
C PC+C+GN N C +G C+ C NT G C C G+ GD+I + C C
Sbjct: 14 CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCP 68
Query: 1932 CDEFGMAD----CDSTTGT--CVCRPGVIGEKCDRCAP 1963
C +A+ C G C+C G C+R +P
Sbjct: 69 CPLPHLANFAESCYRKNGAVRCICNENYAGPNCERPSP 106
Score = 52.8 bits (121), Expect = 2e-05
Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 25/108 (23%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
C PC+C+ ++ EC +G G C++CQ NT G +C KC Y
Sbjct: 14 CVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGYIGD 55
Query: 348 YGKRWDELDVCQPCQCD-PHFS--TGNCEEESG--RCECRPEFQPPDC 390
+ + CQPC C PH + +C ++G RC C + P+C
Sbjct: 56 SIRGAPQF--CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNC 101
Score = 48.8 bits (111), Expect = 4e-04
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 17/105 (16%)
Query: 393 CAYGYFDYPN--CKPCTCNLNGTEGEHCTPTDGLCP-CKYNYAGKSCEICEDGYY----- 444
C G+F + C PC CN N E C G C C+ N G+ CE C DGY
Sbjct: 2 CNAGFFHTLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR 58
Query: 445 -SPE-CKNCECNT--VGSVSYVCDKLTG--DCTCKSKYSGRTCNQ 483
+P+ C+ C C + + + C + G C C Y+G C +
Sbjct: 59 GAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 103
Score = 48.0 bits (109), Expect = 6e-04
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 12/106 (11%)
Query: 1373 CRTGYYGFPN--CRPCHCP--STAICDDNGMCI-CPKNVEGENCDRCKPYTFNFDVQRG- 1426
C G++ + C PC C S D +G C+ C +N GE+C++C ++
Sbjct: 2 CNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 61
Query: 1427 --CDDCNCNPLGVVGNQLQ-CEADSG--KCACRENVRGRVCDHCVP 1467
C C C PL + N + C +G +C C EN G C+ P
Sbjct: 62 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERPSP 106
Score = 47.6 bits (108), Expect = 8e-04
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
Query: 1974 CTPCNCGIASESTQCDDDNGQC-RCAKGVTGKQCDQCAAGFWNYTKDG----CDHCNCNT 2028
C PC+C S +C D +G C C + TG+ C++C G+ + G C C C
Sbjct: 14 CVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 71
Query: 2029 GYSVGF--MC---NATGQCECLPGVIGEKCDR 2055
+ F C N +C C G C+R
Sbjct: 72 PHLANFAESCYRKNGAVRCICNENYAGPNCER 103
Score = 47.6 bits (108), Expect = 8e-04
Identities = 32/91 (35%), Positives = 40/91 (43%), Gaps = 17/91 (18%)
Query: 1342 CDFMGSTELECNTFGGQCP-CKPNVIGRTCSACRTGYYG-----FPN-CRPCHCPSTAIC 1394
CD G++ EC G C C+ N G C C GY G P C+PC CP +
Sbjct: 17 CDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA 75
Query: 1395 D-------DNGM--CICPKNVEGENCDRCKP 1416
+ NG CIC +N G NC+R P
Sbjct: 76 NFAESCYRKNGAVRCICNENYAGPNCERPSP 106
Score = 45.2 bits (102), Expect = 0.005
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 17/107 (15%)
Query: 529 QCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC-NCLTNFGGAQCDQCSPGYY-- 585
+C +G++ + G +CVPC+C+ G+++ G C +C N G C++C GY
Sbjct: 1 KCNAGFFHTLSG---ECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 55
Query: 586 ---KYPD-CLSCNCDVS--GSIGSTC-DDNGL--CHCKSNFDGAKCD 623
P C C C + + +C NG C C N+ G C+
Sbjct: 56 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCE 102
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 13/97 (13%)
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCV-CKQHVGERQCDQCLDGFY--RLQTNDVFGCTEC 746
C C+CN G N C SG CV C+++ C++CLDG+ ++ F C C
Sbjct: 14 CVPCDCN--GNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 67
Query: 747 DCDIG--GSIDNNCDKTTG--QCHCHSRVEGRRCDQP 779
C + + +C + G +C C+ G C++P
Sbjct: 68 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERP 104
Score = 42.3 bits (95), Expect = 0.032
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDRCAPDHWG---L 1968
C GF+ S C C C+ +C +G CV C+ GE C++C + G
Sbjct: 2 CNAGFFHT--LSGECVPCDCNG-NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR 58
Query: 1969 NTGLGCTPCNC---GIASESTQCDDDNG--QCRCAKGVTGKQCDQ 2008
C PC C +A+ + C NG +C C + G C++
Sbjct: 59 GAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 103
Score = 38.3 bits (85), Expect = 0.52
Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 10/63 (15%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CNG+++ C D +G CQ NT G C KC G+ R + + C+P
Sbjct: 17 CDCNGNSNEC--LDGSG----YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF----CQP 66
Query: 291 CNC 293
C C
Sbjct: 67 CPC 69
Score = 38.3 bits (85), Expect = 0.52
Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 6/83 (7%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI 1894
+GS +CQ G CE C GY G D+ +C+PC C SC
Sbjct: 28 DGSGYCVHCQRNTTGEHCEKCLDGYIG---DSIRGAPQFCQPCPCPLPHLANFAESCYRK 84
Query: 1895 NG--DCLKCVNNTAGAACNLCAP 1915
NG C+ C N AG C +P
Sbjct: 85 NGAVRCI-CNENYAGPNCERPSP 106
Score = 34.7 bits (76), Expect = 6.4
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 11/62 (17%)
Query: 2008 QCAAGFWNYTKDGCDHCNCN---------TGYSVGFMCNATGQ-CE-CLPGVIGEKCDRC 2056
+C AGF++ C C+CN +GY V N TG+ CE CL G IG+
Sbjct: 1 KCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGA 60
Query: 2057 PE 2058
P+
Sbjct: 61 PQ 62
>AF522196-1|AAN45861.1| 870|Homo sapiens scavenger receptor type F
protein.
Length = 870
Score = 109 bits (263), Expect = 1e-22
Identities = 117/426 (27%), Positives = 156/426 (36%), Gaps = 77/426 (18%)
Query: 377 GRCECR-PEFQPPDCSSCAYGYFDYPNCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAG 433
GR CR P Q P C CA C C N T E E C G C C++ Y G
Sbjct: 50 GRNVCRAPGSQVPTC--CAGWRQQGDECGIAVCEGNSTCSENEVCV-RPGECRCRHGYFG 106
Query: 434 KSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN---QCQAGY 488
+C+ C ++ P+CK C C+ G C+ +TG CTC ++ G C QCQ G
Sbjct: 107 ANCDTKCPRQFWGPDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHGT 162
Query: 489 YNYPTCKPCNCDTS--GTE---------PSICDDVSGQCICKAGFGGPRCDQ---CLSGY 534
+P C C+ G + S CD +G C+C AG+ G C+ C S
Sbjct: 163 C-HPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSP 221
Query: 535 YMQVLGR---ERQCVPCNCDPTGSTSTS-CS-ADGKCNCLTNFGGAQC-DQCSPGYYKYP 588
Q GR + CD C DG C C + G C + C G+Y
Sbjct: 222 CEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLG 281
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRG--- 644
C G T + C+ ++G KCD C FY C G
Sbjct: 282 CRRRCG-QCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHAC 340
Query: 645 --VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
VT C + G+ C+ K G DC F C C
Sbjct: 341 NHVTGKCTRCNAGWIGDRCETKCS-NGTYGEDCA-----------FVCADCGS------- 381
Query: 703 SLGACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDK 760
G C+ +SG+C+C V C+ C G + C + C C ++ CD
Sbjct: 382 --GHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD------CAQACSCH-----EDTCDP 428
Query: 761 TTGQCH 766
TG CH
Sbjct: 429 VTGACH 434
Score = 97.1 bits (231), Expect = 1e-18
Identities = 104/388 (26%), Positives = 146/388 (37%), Gaps = 72/388 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC+H G C+ C Q W E C+CH H +C ++
Sbjct: 98 CRCRHGYFGANCDTKCP---------RQFWGPDCKELCSCHPHG-QC------EDVTGQC 141
Query: 314 DINGRYEGGGKC---LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG 370
+ R G +C CQH T CR P W C C +T
Sbjct: 142 TCHAR-RWGARCEHACQCQHGTCHPRSGACR---CEP---GWWGAQCASACYCS---ATS 191
Query: 371 NCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKP-CTCNLN--GTEGEH--------C 418
C+ ++G C C + C++ CA C C G + C
Sbjct: 192 RCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRC 251
Query: 419 TPTDGLCPCKYNYAGKSC-EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDC-TCKSKY 476
P DG C C+ Y GK C E C G+Y C+ C C G C TC+ +
Sbjct: 252 HPVDGTCACEPGYRGKYCREPCPAGFYGLGCRR-RCGQCKG-QQPCTVAEGRCLTCEPGW 309
Query: 477 SGRTCNQ-CQAGYYN---YPTCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD-QC 530
+G C+Q C G+Y C PC + C+ V+G+C C AG+ G RC+ +C
Sbjct: 310 NGTKCDQPCATGFYGEGCSHRCPPCR------DGHACNHVTGKCTRCNAGWIGDRCETKC 363
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPD 589
+G Y G + V +C GS + G+C C G C+ C PG +
Sbjct: 364 SNGTY----GEDCAFVCADC---GSGHCDFQS-GRCLCSPGVHGPHCNVTCPPGLHGADC 415
Query: 590 CLSCNCDVSGSIGSTCDD-NGLCHCKSN 616
+C+C TCD G CH ++N
Sbjct: 416 AQACSCH-----EDTCDPVTGACHLETN 438
Score = 94.7 bits (225), Expect = 6e-18
Identities = 106/355 (29%), Positives = 153/355 (43%), Gaps = 59/355 (16%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKP-CNCDTSGTEPSI 508
CE N+ S + VC + G+C C+ Y G C+ +C ++ P CK C+C G
Sbjct: 80 CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQ---- 133
Query: 509 CDDVSGQCICKAGFGGPRCD---QCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK 565
C+DV+GQC C A G RC+ QC G G R C P +++ CSA +
Sbjct: 134 CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACR-CEPGWWGAQCASACYCSATSR 192
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDT 624
C+ T GA C C G++ C C+ S C+ +G C C+ GA+CD
Sbjct: 193 CDPQT---GA-C-LCHAGWWGRSCNNQCACN-----SSPCEQQSGRCQCRERTFGARCDR 242
Query: 625 CREQFYN--YPACEECNCDP--RG------VTASFAGCGSVPAGELCQCKDR-----VQG 669
+ F +P C C+P RG A F G G QCK + +G
Sbjct: 243 YCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGC--RRRCGQCKGQQPCTVAEG 300
Query: 670 RICNDCKPLYWNLQEYNP-----FGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQ-HVGE 722
R C C+P WN + + F E C+ + ACN +G+C C +G+
Sbjct: 301 R-CLTCEP-GWNGTKCDQPCATGFYGEGCS-HRCPPCRDGHACNHVTGKCTRCNAGWIGD 357
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R +C +G Y + F C +C GS +CD +G+C C V G C+
Sbjct: 358 RCETKCSNGTY--GEDCAFVCADC-----GS--GHCDFQSGRCLCSPGVHGPHCN 403
Score = 93.9 bits (223), Expect = 1e-17
Identities = 100/344 (29%), Positives = 133/344 (38%), Gaps = 54/344 (15%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVP-CQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC+C Y G +C+ + P C C C+ H QC+ TG C C G C
Sbjct: 97 ECRCRHGYFGANCDTKCPRQFWGPD--CKELCSCHPHG-QCEDVTGQC-TCHARRWGARC 152
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENG----SLISCNCQPGYGG 1849
E HG PR C C + A +C S +C C G+ G
Sbjct: 153 EHACQCQHGTC---HPRSG-ACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWG 208
Query: 1850 ARC-EYCAAG------YYGIPEDTDLHTGDYC-KPCNCSGNINPQDPGSCDSINGDCLKC 1901
C CA G + + G C + C C G C ++G C C
Sbjct: 209 RSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCF-------RGRCHPVDGTC-AC 260
Query: 1902 VNNTAGAAC-NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
G C C GFYG + C C G C G C+ C PG G KCD
Sbjct: 261 EPGYRGKYCREPCPAGFYGLGC-RRRCGQC----KGQQPCTVAEGRCLTCEPGWNGTKCD 315
Query: 1960 R-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGVTGKQCD-QCAAGFWNY 2016
+ CA +G C PC G A C+ G+C RC G G +C+ +C+ G Y
Sbjct: 316 QPCATGFYGEGCSHRCPPCRDGHA-----CNHVTGKCTRCNAGWIGDRCETKCSNG--TY 368
Query: 2017 TKDGCDHC-NCNTGYSVGFMCN-ATGQCECLPGVIGEKCD-RCP 2057
+D C +C +G+ C+ +G+C C PGV G C+ CP
Sbjct: 369 GEDCAFVCADCGSGH-----CDFQSGRCLCSPGVHGPHCNVTCP 407
Score = 90.6 bits (215), Expect = 9e-17
Identities = 107/410 (26%), Positives = 150/410 (36%), Gaps = 70/410 (17%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP 401
PT + ++ DE + C+ + S G C CR + +C + F P
Sbjct: 62 PTCCAGWRQQGDECGIAV-CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP 120
Query: 402 NCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE---ICEDGYYSPECKNCECN--- 454
+CK C+C+ +G C G C C G CE C+ G P C C
Sbjct: 121 DCKELCSCHPHG----QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGW 176
Query: 455 ---TVGSVSYV-----CDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKP----CNC-- 499
S Y CD TG C C + + GR+C NQC N C+ C C
Sbjct: 177 WGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCAC---NSSPCEQQSGRCQCRE 233
Query: 500 DTSGTE--------PSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNC 550
T G C V G C C+ G+ G C + C +G+Y LG R+C C
Sbjct: 234 RTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFY--GLGCRRRCGQCK- 290
Query: 551 DPTGSTSTSCSADGKC-NCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD- 607
A+G+C C + G +CDQ C+ G+ Y + S C G C+
Sbjct: 291 ----GQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF--YGEGCSHRCPPCRD-GHACNHV 343
Query: 608 NGLC-HCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFAGCGSVP-AGELCQCK 664
G C C + + G +C+T C Y E+C + G G C C
Sbjct: 344 TGKCTRCNAGWIGDRCETKCSNGTYG----EDC-----AFVCADCGSGHCDFQSGRCLCS 394
Query: 665 DRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
V G CN C P C + C+ GAC+ ++ Q
Sbjct: 395 PGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPV-----TGACHLETNQ 439
Score = 89.4 bits (212), Expect = 2e-16
Identities = 95/320 (29%), Positives = 123/320 (38%), Gaps = 64/320 (20%)
Query: 1735 ECQCPRAYRGLSCE---QCAEG--HYRLPSGFCVP----------CQCNGHSDQCDVNTG 1779
+C C G CE QC G H R + C P C C+ S +CD TG
Sbjct: 140 QCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATS-RCDPQTG 198
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDL---SENG 1836
CL C G C + + R C C F CD G
Sbjct: 199 ACL-CHAGWWGRSCNNQCACNSSPCEQQSGR----CQCR----ERTFGARCDRYCQCFRG 249
Query: 1837 SLI----SCNCQPGYGGARC-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC 1891
+C C+PGY G C E C AG+YG+ C+ C G Q P C
Sbjct: 250 RCHPVDGTCACEPGYRGKYCREPCPAGFYGLG----------CRR-RC-GQCKGQQP--C 295
Query: 1892 DSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-C 1949
G CL C G C+ CA GFYG+ S C C G A C+ TG C C
Sbjct: 296 TVAEGRCLTCEPGWNGTKCDQPCATGFYGEGC-SHRCPPC---RDGHA-CNHVTGKCTRC 350
Query: 1950 RPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD- 2007
G IG++C+ +C+ +G + C C G CD +G+C C+ GV G C+
Sbjct: 351 NAGWIGDRCETKCSNGTYGEDCAFVCADCGSG------HCDFQSGRCLCSPGVHGPHCNV 404
Query: 2008 QCAAGFWNYTKDGCDHCNCN 2027
C G + D C+C+
Sbjct: 405 TCPPGL--HGADCAQACSCH 422
Score = 84.6 bits (200), Expect = 6e-15
Identities = 77/247 (31%), Positives = 106/247 (42%), Gaps = 53/247 (21%)
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHC-EFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CQC +C G C C G +C E C +G++G +G R C C P
Sbjct: 244 CQC--FRGRCHPVDGTCA-CEPGYRGKYCREPCPAGFYG---LGCRRRCGQCKGQQP--- 294
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGN 1882
C ++E L C+PG+ G +C+ CA G+YG + H C PC
Sbjct: 295 ------CTVAEGRCL---TCEPGWNGTKCDQPCATGFYG---EGCSHR---CPPC----- 334
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCD 1941
+D +C+ + G C +C G C C+ G YG+ +C A +C + G CD
Sbjct: 335 ---RDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGE-----DC-AFVCADCGSGHCD 385
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRC--- 1997
+G C+C PGV G C+ P GL+ G C C+C E T CD G C
Sbjct: 386 FQSGRCLCSPGVHGPHCNVTCPP--GLH-GADCAQACSC---HEDT-CDPVTGACHLETN 438
Query: 1998 -AKGVTG 2003
KGV G
Sbjct: 439 QRKGVMG 445
Score = 79.8 bits (188), Expect = 2e-13
Identities = 79/291 (27%), Positives = 109/291 (37%), Gaps = 36/291 (12%)
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFG 573
G+ +C+A G + C +G+ Q G E C + T S + C G+C C +
Sbjct: 50 GRNVCRAP--GSQVPTCCAGWRQQ--GDECGIAVCEGNSTCSENEVCVRPGECRCRHGYF 105
Query: 574 GAQCDQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFY 630
GA CD P + PDC C+C G C+D G C C + GA+C+ C+ Q
Sbjct: 106 GANCDTKCPRQFWGPDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHG 161
Query: 631 N-YPACEECNCDP---RGVTASFAGCGSV----PAGELCQCKDRVQGRICNDCKPLYWNL 682
+P C C+P AS C + P C C GR CN+ +
Sbjct: 162 TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSP 221
Query: 683 QEYNPFGCEQCNCNLAGTLNS------LGACNTKSGQCVCKQHVGERQC-DQCLDGFYRL 735
E C QC G G C+ G C C+ + C + C GFY L
Sbjct: 222 CEQQSGRC-QCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL 280
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGRRCDQPIRAHYF 785
GC G C G+C C G +CDQP ++
Sbjct: 281 ------GCRRRCGQCKG--QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Score = 72.5 bits (170), Expect = 3e-11
Identities = 74/262 (28%), Positives = 106/262 (40%), Gaps = 49/262 (18%)
Query: 1841 CNCQPGYGGARCE-YCAAGYYGIPEDTDL---HTGDYCK----PCNC-SGNINPQDPGSC 1891
C C+ GY GA C+ C ++G P+ +L H C+ C C + + +C
Sbjct: 98 CRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHAC 156
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRP 1951
+G C + AC C PG++G ++ +AC C + CD TG C+C
Sbjct: 157 QCQHGTC-----HPRSGACR-CEPGWWG----AQCASACYCS--ATSRCDPQTGACLCHA 204
Query: 1952 GVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCD-----------DDNGQCRCAK 1999
G G C ++CA + G C C + +CD +G C C
Sbjct: 205 GWWGRSCNNQCACNSSPCEQQSG--RCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEP 262
Query: 2000 GVTGKQC-DQCAAGFWNY-TKDGCDHCNCNTGYSVGFMCNATGQC-ECLPGVIGEKCDR- 2055
G GK C + C AGF+ + C C +V A G+C C PG G KCD+
Sbjct: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTV-----AEGRCLTCEPGWNGTKCDQP 317
Query: 2056 CPERWVLIPQEGCL-ECDSCTD 2076
C + EGC C C D
Sbjct: 318 CATGFY---GEGCSHRCPPCRD 336
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/162 (31%), Positives = 66/162 (40%), Gaps = 25/162 (15%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSA-CRTGYYG---FPNCRPCHCPSTAICDDNGMCI-CPKN 1405
C G+C C+P G C C TG+YG C PC A G C C
Sbjct: 295 CTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCR-DGHACNHVTGKCTRCNAG 353
Query: 1406 VEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD- 1463
G+ C+ +C T+ D C DC C+ SG+C C V G C+
Sbjct: 354 WIGDRCETKCSNGTYGEDCAFVCADCGSG---------HCDFQSGRCLCSPGVHGPHCNV 404
Query: 1464 HCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
C PG + DC Q C+C+ D CD T C+ +TN R
Sbjct: 405 TCPPGLHG-ADCAQACSCHE-----DTCDPVTGACHLETNQR 440
Score = 58.0 bits (134), Expect = 6e-07
Identities = 57/214 (26%), Positives = 79/214 (36%), Gaps = 38/214 (17%)
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTA 1929
GD C C GN + C G+C +C + GA C+ C F+G +C
Sbjct: 72 GDECGIAVCEGNSTCSENEVCVR-PGEC-RCRHGYFGANCDTKCPRQFWGP-----DCKE 124
Query: 1930 -CICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCG------- 1980
C C G C+ TG C C G +C+ C H + G C G
Sbjct: 125 LCSCHPHGQ--CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCA 182
Query: 1981 ---IASESTQCDDDNGQCRCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMC 2036
S +++CD G C C G G+ C +QCA + + C C + G C
Sbjct: 183 SACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNS-SPCEQQSGRCQCRE-RTFGARC 240
Query: 2037 N------------ATGQCECLPGVIGEKC-DRCP 2057
+ G C C PG G+ C + CP
Sbjct: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCP 274
Score = 57.6 bits (133), Expect = 8e-07
Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 28/197 (14%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC-SACRTGYYGF 1380
CRE F + R C C F G C+ G C C+P G+ C C G+YG
Sbjct: 231 CRERTFGARCD-----RYCQC-FRG----RCHPVDGTCACEPGYRGKYCREPCPAGFYGL 280
Query: 1381 PNCRPC-HCPSTAICD-DNGMCI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
R C C C G C+ C G CD +P F GC C P
Sbjct: 281 GCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCD--QPCATGF-YGEGCSH-RCPP--- 333
Query: 1438 VGNQLQCEADSGKCA-CRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTA 1495
+ C +GKC C G C+ C G Y DC C G+ + CD +
Sbjct: 334 CRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYG-EDC-AFVCADCGSGH--CDFQSG 389
Query: 1496 QCYCKTNVRGQACD-TC 1511
+C C V G C+ TC
Sbjct: 390 RCLCSPGVHGPHCNVTC 406
Score = 55.6 bits (128), Expect = 3e-06
Identities = 40/164 (24%), Positives = 60/164 (36%), Gaps = 29/164 (17%)
Query: 1357 GQCPCKPNVIGRTC-SACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEGENCDR 1413
G+C C+ G C + C ++G P+C+ C C C+D G C C G C+
Sbjct: 96 GECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEH 154
Query: 1414 --------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
C P + + G C +C+ +G C C GR C++
Sbjct: 155 ACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNN- 213
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
QC CN C+Q + +C C+ G CD
Sbjct: 214 -----------QCACNS-----SPCEQQSGRCQCRERTFGARCD 241
Score = 52.8 bits (121), Expect = 2e-05
Identities = 49/203 (24%), Positives = 75/203 (36%), Gaps = 23/203 (11%)
Query: 1359 CPCKPNVIGRTCSACRT--GYYGFPNCRPCHCPSTAICD-DNGMCICPKNVEGENC-DRC 1414
C C+ ACR G++G C+C +T+ CD G C+C G +C ++C
Sbjct: 156 CQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQC 215
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQL------QCEADSGKCACRENVRGRVC-DHCVP 1467
+ + Q G C G ++ +C G CAC RG+ C + C
Sbjct: 216 ACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPA 275
Query: 1468 GHYAFPDCYQC-TCNRHGTTYDVCDQNTAQCY-CKTNVRGQACD-TCKEEYFNLQDDN-- 1522
G Y +C C C +C C+ G CD C ++ +
Sbjct: 276 GFYGLGCRRRCGQCKGQ----QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRC 331
Query: 1523 ---PDGCTKCFCFGKTTRCSSSY 1542
DG GK TRC++ +
Sbjct: 332 PPCRDGHACNHVTGKCTRCNAGW 354
Score = 49.2 bits (112), Expect = 3e-04
Identities = 45/167 (26%), Positives = 62/167 (37%), Gaps = 21/167 (12%)
Query: 1388 CPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
C +C G C C G NCD +C + D + + C+C+P G QCE
Sbjct: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK---ELCSCHPHG------QCED 136
Query: 1447 DSGKCACRENVRGRVCDH-CVPGH-YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G+C C G C+H C H P C C G C + CYC R
Sbjct: 137 VTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRC-EPGWWGAQC---ASACYCSATSR 192
Query: 1505 GQ----ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAA 1547
AC C ++ +N C C ++ RC T+ A
Sbjct: 193 CDPQTGAC-LCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGA 238
Score = 48.0 bits (109), Expect = 6e-04
Identities = 54/210 (25%), Positives = 79/210 (37%), Gaps = 31/210 (14%)
Query: 227 IGGRCMCN-GHADT-CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
+ G C C G+ C PAG L CR + C Q + C+ E + W+
Sbjct: 254 VDGTCACEPGYRGKYCREPCPAGFYG-LGCRRRCGQCKGQ--QPCTVAEGRCLTCEPGWN 310
Query: 285 RFSCE-PCNCHNHTTECTYD-PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN-KCR 341
C+ PC + C++ P + + G KC C G C KC
Sbjct: 311 GTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTG------KCTRCNAGWIGDRCETKCS 364
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDY 400
YG+ D VC C +G+C+ +SGRC C P P C+ +C G
Sbjct: 365 NG---TYGE--DCAFVCADC------GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGA 413
Query: 401 PNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+ C+C+ + C P G C + N
Sbjct: 414 DCAQACSCH-----EDTCDPVTGACHLETN 438
Score = 39.5 bits (88), Expect = 0.22
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNC--NTGYSVGFMCNATGQCECLPGVIGEKCD-RCPER 2059
G Q C AG W D C C N+ S +C G+C C G G CD +CP +
Sbjct: 58 GSQVPTCCAG-WRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQ 116
Query: 2060 W 2060
+
Sbjct: 117 F 117
Score = 39.1 bits (87), Expect = 0.30
Identities = 37/145 (25%), Positives = 54/145 (37%), Gaps = 21/145 (14%)
Query: 655 VPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
V GE C+C+ G C+ C +W P E C+C+ G C +GQ
Sbjct: 93 VRPGE-CRCRHGYFGANCDTKCPRQFWG-----PDCKELCSCH------PHGQCEDVTGQ 140
Query: 714 CVCKQHVGERQCD---QCLDGFYRLQTNDV-----FGCTECDCDIGGSIDNNCDKTTGQC 765
C C +C+ QC G ++ + +C S + CD TG C
Sbjct: 141 CTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGAC 200
Query: 766 HCHSRVEGRRCDQPIRAHYFPTLHQ 790
CH+ GR C+ + P Q
Sbjct: 201 LCHAGWWGRSCNNQCACNSSPCEQQ 225
>AB024433-1|BAD93345.1| 866|Homo sapiens NSR1 protein.
Length = 866
Score = 109 bits (263), Expect = 1e-22
Identities = 117/426 (27%), Positives = 156/426 (36%), Gaps = 77/426 (18%)
Query: 377 GRCECR-PEFQPPDCSSCAYGYFDYPNCKPCTCNLNGT--EGEHCTPTDGLCPCKYNYAG 433
GR CR P Q P C CA C C N T E E C G C C++ Y G
Sbjct: 50 GRNVCRAPGSQVPTC--CAGWRQQGDECGIAVCEGNSTCSENEVCV-RPGECRCRHGYFG 106
Query: 434 KSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN---QCQAGY 488
+C+ C ++ P+CK C C+ G C+ +TG CTC ++ G C QCQ G
Sbjct: 107 ANCDTKCPRQFWGPDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHGT 162
Query: 489 YNYPTCKPCNCDTS--GTE---------PSICDDVSGQCICKAGFGGPRCDQ---CLSGY 534
+P C C+ G + S CD +G C+C AG+ G C+ C S
Sbjct: 163 C-HPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSP 221
Query: 535 YMQVLGR---ERQCVPCNCDPTGSTSTS-CS-ADGKCNCLTNFGGAQC-DQCSPGYYKYP 588
Q GR + CD C DG C C + G C + C G+Y
Sbjct: 222 CEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLG 281
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEECNCDPRG--- 644
C G T + C+ ++G KCD C FY C G
Sbjct: 282 CRRRCG-QCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHAC 340
Query: 645 --VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
VT C + G+ C+ K G DC F C C
Sbjct: 341 NHVTGKCTRCNAGWIGDRCETKCS-NGTYGEDCA-----------FVCADCGS------- 381
Query: 703 SLGACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDK 760
G C+ +SG+C+C V C+ C G + C + C C ++ CD
Sbjct: 382 --GHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD------CAQACSCH-----EDTCDP 428
Query: 761 TTGQCH 766
TG CH
Sbjct: 429 VTGACH 434
Score = 97.1 bits (231), Expect = 1e-18
Identities = 104/388 (26%), Positives = 146/388 (37%), Gaps = 72/388 (18%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC+H G C+ C Q W E C+CH H +C ++
Sbjct: 98 CRCRHGYFGANCDTKCP---------RQFWGPDCKELCSCHPHG-QC------EDVTGQC 141
Query: 314 DINGRYEGGGKC---LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG 370
+ R G +C CQH T CR P W C C +T
Sbjct: 142 TCHAR-RWGARCEHACQCQHGTCHPRSGACR---CEP---GWWGAQCASACYCS---ATS 191
Query: 371 NCEEESGRCECRPEFQPPDCSS-CAYGYFDYPNCKP-CTCNLN--GTEGEH--------C 418
C+ ++G C C + C++ CA C C G + C
Sbjct: 192 RCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRC 251
Query: 419 TPTDGLCPCKYNYAGKSC-EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDC-TCKSKY 476
P DG C C+ Y GK C E C G+Y C+ C C G C TC+ +
Sbjct: 252 HPVDGTCACEPGYRGKYCREPCPAGFYGLGCRR-RCGQCKG-QQPCTVAEGRCLTCEPGW 309
Query: 477 SGRTCNQ-CQAGYYN---YPTCKPCNCDTSGTEPSICDDVSGQCI-CKAGFGGPRCD-QC 530
+G C+Q C G+Y C PC + C+ V+G+C C AG+ G RC+ +C
Sbjct: 310 NGTKCDQPCATGFYGEGCSHRCPPCR------DGHACNHVTGKCTRCNAGWIGDRCETKC 363
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD-QCSPGYYKYPD 589
+G Y G + V +C GS + G+C C G C+ C PG +
Sbjct: 364 SNGTY----GEDCAFVCADC---GSGHCDFQS-GRCLCSPGVHGPHCNVTCPPGLHGADC 415
Query: 590 CLSCNCDVSGSIGSTCDD-NGLCHCKSN 616
+C+C TCD G CH ++N
Sbjct: 416 AQACSCH-----EDTCDPVTGACHLETN 438
Score = 94.7 bits (225), Expect = 6e-18
Identities = 106/355 (29%), Positives = 153/355 (43%), Gaps = 59/355 (16%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKP-CNCDTSGTEPSI 508
CE N+ S + VC + G+C C+ Y G C+ +C ++ P CK C+C G
Sbjct: 80 CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQ---- 133
Query: 509 CDDVSGQCICKAGFGGPRCD---QCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK 565
C+DV+GQC C A G RC+ QC G G R C P +++ CSA +
Sbjct: 134 CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACR-CEPGWWGAQCASACYCSATSR 192
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDT 624
C+ T GA C C G++ C C+ S C+ +G C C+ GA+CD
Sbjct: 193 CDPQT---GA-C-LCHAGWWGRSCNNQCACN-----SSPCEQQSGRCQCRERTFGARCDR 242
Query: 625 CREQFYN--YPACEECNCDP--RG------VTASFAGCGSVPAGELCQCKDR-----VQG 669
+ F +P C C+P RG A F G G QCK + +G
Sbjct: 243 YCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGC--RRRCGQCKGQQPCTVAEG 300
Query: 670 RICNDCKPLYWNLQEYNP-----FGCEQCNCNLAGTLNSLGACNTKSGQCV-CKQ-HVGE 722
R C C+P WN + + F E C+ + ACN +G+C C +G+
Sbjct: 301 R-CLTCEP-GWNGTKCDQPCATGFYGEGCS-HRCPPCRDGHACNHVTGKCTRCNAGWIGD 357
Query: 723 RQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R +C +G Y + F C +C GS +CD +G+C C V G C+
Sbjct: 358 RCETKCSNGTY--GEDCAFVCADC-----GS--GHCDFQSGRCLCSPGVHGPHCN 403
Score = 93.9 bits (223), Expect = 1e-17
Identities = 100/344 (29%), Positives = 133/344 (38%), Gaps = 54/344 (15%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVP-CQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
EC+C Y G +C+ + P C C C+ H QC+ TG C C G C
Sbjct: 97 ECRCRHGYFGANCDTKCPRQFWGPD--CKELCSCHPHG-QCEDVTGQC-TCHARRWGARC 152
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENG----SLISCNCQPGYGG 1849
E HG PR C C + A +C S +C C G+ G
Sbjct: 153 EHACQCQHGTC---HPRSG-ACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWG 208
Query: 1850 ARC-EYCAAG------YYGIPEDTDLHTGDYC-KPCNCSGNINPQDPGSCDSINGDCLKC 1901
C CA G + + G C + C C G C ++G C C
Sbjct: 209 RSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCF-------RGRCHPVDGTC-AC 260
Query: 1902 VNNTAGAAC-NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCD 1959
G C C GFYG + C C G C G C+ C PG G KCD
Sbjct: 261 EPGYRGKYCREPCPAGFYGLGC-RRRCGQC----KGQQPCTVAEGRCLTCEPGWNGTKCD 315
Query: 1960 R-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGVTGKQCD-QCAAGFWNY 2016
+ CA +G C PC G A C+ G+C RC G G +C+ +C+ G Y
Sbjct: 316 QPCATGFYGEGCSHRCPPCRDGHA-----CNHVTGKCTRCNAGWIGDRCETKCSNG--TY 368
Query: 2017 TKDGCDHC-NCNTGYSVGFMCN-ATGQCECLPGVIGEKCD-RCP 2057
+D C +C +G+ C+ +G+C C PGV G C+ CP
Sbjct: 369 GEDCAFVCADCGSGH-----CDFQSGRCLCSPGVHGPHCNVTCP 407
Score = 90.6 bits (215), Expect = 9e-17
Identities = 107/410 (26%), Positives = 150/410 (36%), Gaps = 70/410 (17%)
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP 401
PT + ++ DE + C+ + S G C CR + +C + F P
Sbjct: 62 PTCCAGWRQQGDECGIAV-CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP 120
Query: 402 NCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE---ICEDGYYSPECKNCECN--- 454
+CK C+C+ +G C G C C G CE C+ G P C C
Sbjct: 121 DCKELCSCHPHG----QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGW 176
Query: 455 ---TVGSVSYV-----CDKLTGDCTCKSKYSGRTC-NQCQAGYYNYPTCKP----CNC-- 499
S Y CD TG C C + + GR+C NQC N C+ C C
Sbjct: 177 WGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCAC---NSSPCEQQSGRCQCRE 233
Query: 500 DTSGTE--------PSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNC 550
T G C V G C C+ G+ G C + C +G+Y LG R+C C
Sbjct: 234 RTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFY--GLGCRRRCGQCK- 290
Query: 551 DPTGSTSTSCSADGKC-NCLTNFGGAQCDQ-CSPGYYKYPDCLSCNCDVSGSIGSTCDD- 607
A+G+C C + G +CDQ C+ G+ Y + S C G C+
Sbjct: 291 ----GQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF--YGEGCSHRCPPCRD-GHACNHV 343
Query: 608 NGLC-HCKSNFDGAKCDT-CREQFYNYPACEECNCDPRGVTASFAGCGSVP-AGELCQCK 664
G C C + + G +C+T C Y E+C + G G C C
Sbjct: 344 TGKCTRCNAGWIGDRCETKCSNGTYG----EDC-----AFVCADCGSGHCDFQSGRCLCS 394
Query: 665 DRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
V G CN C P C + C+ GAC+ ++ Q
Sbjct: 395 PGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPV-----TGACHLETNQ 439
Score = 89.4 bits (212), Expect = 2e-16
Identities = 95/320 (29%), Positives = 123/320 (38%), Gaps = 64/320 (20%)
Query: 1735 ECQCPRAYRGLSCE---QCAEG--HYRLPSGFCVP----------CQCNGHSDQCDVNTG 1779
+C C G CE QC G H R + C P C C+ S +CD TG
Sbjct: 140 QCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATS-RCDPQTG 198
Query: 1780 ICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDL---SENG 1836
CL C G C + + R C C F CD G
Sbjct: 199 ACL-CHAGWWGRSCNNQCACNSSPCEQQSGR----CQCR----ERTFGARCDRYCQCFRG 249
Query: 1837 SLI----SCNCQPGYGGARC-EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC 1891
+C C+PGY G C E C AG+YG+ C+ C G Q P C
Sbjct: 250 RCHPVDGTCACEPGYRGKYCREPCPAGFYGLG----------CRR-RC-GQCKGQQP--C 295
Query: 1892 DSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-C 1949
G CL C G C+ CA GFYG+ S C C G A C+ TG C C
Sbjct: 296 TVAEGRCLTCEPGWNGTKCDQPCATGFYGEGC-SHRCPPC---RDGHA-CNHVTGKCTRC 350
Query: 1950 RPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD- 2007
G IG++C+ +C+ +G + C C G CD +G+C C+ GV G C+
Sbjct: 351 NAGWIGDRCETKCSNGTYGEDCAFVCADCGSG------HCDFQSGRCLCSPGVHGPHCNV 404
Query: 2008 QCAAGFWNYTKDGCDHCNCN 2027
C G + D C+C+
Sbjct: 405 TCPPGL--HGADCAQACSCH 422
Score = 84.6 bits (200), Expect = 6e-15
Identities = 77/247 (31%), Positives = 106/247 (42%), Gaps = 53/247 (21%)
Query: 1765 CQCNGHSDQCDVNTGICLNCADNTIGDHC-EFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CQC +C G C C G +C E C +G++G +G R C C P
Sbjct: 244 CQC--FRGRCHPVDGTCA-CEPGYRGKYCREPCPAGFYG---LGCRRRCGQCKGQQP--- 294
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGN 1882
C ++E L C+PG+ G +C+ CA G+YG + H C PC
Sbjct: 295 ------CTVAEGRCL---TCEPGWNGTKCDQPCATGFYG---EGCSHR---CPPC----- 334
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCD 1941
+D +C+ + G C +C G C C+ G YG+ +C A +C + G CD
Sbjct: 335 ---RDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGE-----DC-AFVCADCGSGHCD 385
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRC--- 1997
+G C+C PGV G C+ P GL+ G C C+C E T CD G C
Sbjct: 386 FQSGRCLCSPGVHGPHCNVTCPP--GLH-GADCAQACSC---HEDT-CDPVTGACHLETN 438
Query: 1998 -AKGVTG 2003
KGV G
Sbjct: 439 QRKGVMG 445
Score = 79.8 bits (188), Expect = 2e-13
Identities = 79/291 (27%), Positives = 109/291 (37%), Gaps = 36/291 (12%)
Query: 514 GQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFG 573
G+ +C+A G + C +G+ Q G E C + T S + C G+C C +
Sbjct: 50 GRNVCRAP--GSQVPTCCAGWRQQ--GDECGIAVCEGNSTCSENEVCVRPGECRCRHGYF 105
Query: 574 GAQCDQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFY 630
GA CD P + PDC C+C G C+D G C C + GA+C+ C+ Q
Sbjct: 106 GANCDTKCPRQFWGPDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHG 161
Query: 631 N-YPACEECNCDP---RGVTASFAGCGSV----PAGELCQCKDRVQGRICNDCKPLYWNL 682
+P C C+P AS C + P C C GR CN+ +
Sbjct: 162 TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSP 221
Query: 683 QEYNPFGCEQCNCNLAGTLNS------LGACNTKSGQCVCKQHVGERQC-DQCLDGFYRL 735
E C QC G G C+ G C C+ + C + C GFY L
Sbjct: 222 CEQQSGRC-QCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL 280
Query: 736 QTNDVFGCTECDCDIGGSIDNNCDKTTGQC-HCHSRVEGRRCDQPIRAHYF 785
GC G C G+C C G +CDQP ++
Sbjct: 281 ------GCRRRCGQCKG--QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Score = 72.5 bits (170), Expect = 3e-11
Identities = 74/262 (28%), Positives = 106/262 (40%), Gaps = 49/262 (18%)
Query: 1841 CNCQPGYGGARCE-YCAAGYYGIPEDTDL---HTGDYCK----PCNC-SGNINPQDPGSC 1891
C C+ GY GA C+ C ++G P+ +L H C+ C C + + +C
Sbjct: 98 CRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHAC 156
Query: 1892 DSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRP 1951
+G C + AC C PG++G ++ +AC C + CD TG C+C
Sbjct: 157 QCQHGTC-----HPRSGACR-CEPGWWG----AQCASACYCS--ATSRCDPQTGACLCHA 204
Query: 1952 GVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCD-----------DDNGQCRCAK 1999
G G C ++CA + G C C + +CD +G C C
Sbjct: 205 GWWGRSCNNQCACNSSPCEQQSG--RCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEP 262
Query: 2000 GVTGKQC-DQCAAGFWNY-TKDGCDHCNCNTGYSVGFMCNATGQC-ECLPGVIGEKCDR- 2055
G GK C + C AGF+ + C C +V A G+C C PG G KCD+
Sbjct: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTV-----AEGRCLTCEPGWNGTKCDQP 317
Query: 2056 CPERWVLIPQEGCL-ECDSCTD 2076
C + EGC C C D
Sbjct: 318 CATGFY---GEGCSHRCPPCRD 336
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/162 (31%), Positives = 66/162 (40%), Gaps = 25/162 (15%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSA-CRTGYYG---FPNCRPCHCPSTAICDDNGMCI-CPKN 1405
C G+C C+P G C C TG+YG C PC A G C C
Sbjct: 295 CTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCR-DGHACNHVTGKCTRCNAG 353
Query: 1406 VEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD- 1463
G+ C+ +C T+ D C DC C+ SG+C C V G C+
Sbjct: 354 WIGDRCETKCSNGTYGEDCAFVCADCGSG---------HCDFQSGRCLCSPGVHGPHCNV 404
Query: 1464 HCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
C PG + DC Q C+C+ D CD T C+ +TN R
Sbjct: 405 TCPPGLHG-ADCAQACSCHE-----DTCDPVTGACHLETNQR 440
Score = 58.0 bits (134), Expect = 6e-07
Identities = 57/214 (26%), Positives = 79/214 (36%), Gaps = 38/214 (17%)
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTA 1929
GD C C GN + C G+C +C + GA C+ C F+G +C
Sbjct: 72 GDECGIAVCEGNSTCSENEVCVR-PGEC-RCRHGYFGANCDTKCPRQFWGP-----DCKE 124
Query: 1930 -CICDEFGMADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCG------- 1980
C C G C+ TG C C G +C+ C H + G C G
Sbjct: 125 LCSCHPHGQ--CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCA 182
Query: 1981 ---IASESTQCDDDNGQCRCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMC 2036
S +++CD G C C G G+ C +QCA + + C C + G C
Sbjct: 183 SACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNS-SPCEQQSGRCQCRE-RTFGARC 240
Query: 2037 N------------ATGQCECLPGVIGEKC-DRCP 2057
+ G C C PG G+ C + CP
Sbjct: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCP 274
Score = 57.6 bits (133), Expect = 8e-07
Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 28/197 (14%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC-SACRTGYYGF 1380
CRE F + R C C F G C+ G C C+P G+ C C G+YG
Sbjct: 231 CRERTFGARCD-----RYCQC-FRG----RCHPVDGTCACEPGYRGKYCREPCPAGFYGL 280
Query: 1381 PNCRPC-HCPSTAICD-DNGMCI-CPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGV 1437
R C C C G C+ C G CD +P F GC C P
Sbjct: 281 GCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCD--QPCATGF-YGEGCSH-RCPP--- 333
Query: 1438 VGNQLQCEADSGKCA-CRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTA 1495
+ C +GKC C G C+ C G Y DC C G+ + CD +
Sbjct: 334 CRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYG-EDC-AFVCADCGSGH--CDFQSG 389
Query: 1496 QCYCKTNVRGQACD-TC 1511
+C C V G C+ TC
Sbjct: 390 RCLCSPGVHGPHCNVTC 406
Score = 55.6 bits (128), Expect = 3e-06
Identities = 40/164 (24%), Positives = 60/164 (36%), Gaps = 29/164 (17%)
Query: 1357 GQCPCKPNVIGRTC-SACRTGYYGFPNCRP-CHCPSTAICDD-NGMCICPKNVEGENCDR 1413
G+C C+ G C + C ++G P+C+ C C C+D G C C G C+
Sbjct: 96 GECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEH 154
Query: 1414 --------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
C P + + G C +C+ +G C C GR C++
Sbjct: 155 ACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNN- 213
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
QC CN C+Q + +C C+ G CD
Sbjct: 214 -----------QCACNS-----SPCEQQSGRCQCRERTFGARCD 241
Score = 52.8 bits (121), Expect = 2e-05
Identities = 49/203 (24%), Positives = 75/203 (36%), Gaps = 23/203 (11%)
Query: 1359 CPCKPNVIGRTCSACRT--GYYGFPNCRPCHCPSTAICD-DNGMCICPKNVEGENC-DRC 1414
C C+ ACR G++G C+C +T+ CD G C+C G +C ++C
Sbjct: 156 CQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQC 215
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQL------QCEADSGKCACRENVRGRVC-DHCVP 1467
+ + Q G C G ++ +C G CAC RG+ C + C
Sbjct: 216 ACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPA 275
Query: 1468 GHYAFPDCYQC-TCNRHGTTYDVCDQNTAQCY-CKTNVRGQACD-TCKEEYFNLQDDN-- 1522
G Y +C C C +C C+ G CD C ++ +
Sbjct: 276 GFYGLGCRRRCGQCKGQ----QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRC 331
Query: 1523 ---PDGCTKCFCFGKTTRCSSSY 1542
DG GK TRC++ +
Sbjct: 332 PPCRDGHACNHVTGKCTRCNAGW 354
Score = 49.2 bits (112), Expect = 3e-04
Identities = 45/167 (26%), Positives = 62/167 (37%), Gaps = 21/167 (12%)
Query: 1388 CPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
C +C G C C G NCD +C + D + + C+C+P G QCE
Sbjct: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK---ELCSCHPHG------QCED 136
Query: 1447 DSGKCACRENVRGRVCDH-CVPGH-YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G+C C G C+H C H P C C G C + CYC R
Sbjct: 137 VTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRC-EPGWWGAQC---ASACYCSATSR 192
Query: 1505 GQ----ACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAA 1547
AC C ++ +N C C ++ RC T+ A
Sbjct: 193 CDPQTGAC-LCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGA 238
Score = 48.0 bits (109), Expect = 6e-04
Identities = 54/210 (25%), Positives = 79/210 (37%), Gaps = 31/210 (14%)
Query: 227 IGGRCMCN-GHADT-CEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
+ G C C G+ C PAG L CR + C Q + C+ E + W+
Sbjct: 254 VDGTCACEPGYRGKYCREPCPAGFYG-LGCRRRCGQCKGQ--QPCTVAEGRCLTCEPGWN 310
Query: 285 RFSCE-PCNCHNHTTECTYD-PEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCN-KCR 341
C+ PC + C++ P + + G KC C G C KC
Sbjct: 311 GTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTG------KCTRCNAGWIGDRCETKCS 364
Query: 342 PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDY 400
YG+ D VC C +G+C+ +SGRC C P P C+ +C G
Sbjct: 365 NG---TYGE--DCAFVCADC------GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGA 413
Query: 401 PNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
+ C+C+ + C P G C + N
Sbjct: 414 DCAQACSCH-----EDTCDPVTGACHLETN 438
Score = 39.5 bits (88), Expect = 0.22
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNC--NTGYSVGFMCNATGQCECLPGVIGEKCD-RCPER 2059
G Q C AG W D C C N+ S +C G+C C G G CD +CP +
Sbjct: 58 GSQVPTCCAG-WRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQ 116
Query: 2060 W 2060
+
Sbjct: 117 F 117
Score = 39.1 bits (87), Expect = 0.30
Identities = 37/145 (25%), Positives = 54/145 (37%), Gaps = 21/145 (14%)
Query: 655 VPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
V GE C+C+ G C+ C +W P E C+C+ G C +GQ
Sbjct: 93 VRPGE-CRCRHGYFGANCDTKCPRQFWG-----PDCKELCSCH------PHGQCEDVTGQ 140
Query: 714 CVCKQHVGERQCD---QCLDGFYRLQTNDV-----FGCTECDCDIGGSIDNNCDKTTGQC 765
C C +C+ QC G ++ + +C S + CD TG C
Sbjct: 141 CTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGAC 200
Query: 766 HCHSRVEGRRCDQPIRAHYFPTLHQ 790
CH+ GR C+ + P Q
Sbjct: 201 LCHAGWWGRSCNNQCACNSSPCEQQ 225
>D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein.
Length = 830
Score = 107 bits (256), Expect = 1e-21
Identities = 105/359 (29%), Positives = 139/359 (38%), Gaps = 48/359 (13%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQC 1774
G D DE+ V+ C+C + G C G Y P C C C+ H QC
Sbjct: 59 GPDACQKDEVCVKPGL----CRCKPGFFGAHCSSRCPGQYWGPD--CRESCPCHPHG-QC 111
Query: 1775 DVNTGICLNCADNTIGDHCEF-CMSGYHG--DATVGTPR---DCLICACPMPYPSNNFAL 1828
+ TG C C + G CEF C G HG D G C P N A
Sbjct: 112 EPATGAC-QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP 1888
C+ + +C C+PG+ G RC + +G P + D C+P Q
Sbjct: 171 RCEQATG----ACVCKPGWWGRRCSF-RCNCHGSPCEQDSGRCA-CRPGWWGPECQQQCE 224
Query: 1889 ---GSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTT 1944
G C + +G+C C GA C L C G +G + +C C +E C T
Sbjct: 225 CVRGRCSAASGECT-CPPGFRGARCELPCPAGSHGVQC-AHSCGRCKHNE----PCSPDT 278
Query: 1945 GTCV-CRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
G+C C PG G +C + C P +G + C C G A C+ D G C RC G
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA-----CEPDTGHCQRCDPGW 333
Query: 2002 TGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCD-RCP 2057
G +C D C G + + C V C+ TG C C G G C+ CP
Sbjct: 334 LGPRCEDPCPTGTFG------EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 102 bits (244), Expect = 3e-20
Identities = 108/380 (28%), Positives = 148/380 (38%), Gaps = 82/380 (21%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNF----DGAKCDTCREQFYNYPACEE 637
PG+ C + G+ G +C+ HC+ D C C + P CE+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCRHGEACEPDTGHCQRCDPGWLG-PRCED 340
Query: 638 CNCDPRGVTASFAGCGSV-PAGELCQCKDRVQGRICNDCKPLYW--NLQEYNPFGCEQCN 694
C P G CGS P C D V G C YW + P G N
Sbjct: 341 -PC-PTGTFGE--DCGSTCPTCVQGSC-DTVTGDCV--CSAGYWGPSCNASCPAGFHGNN 393
Query: 695 CNLAGTLNSLGACNTKSGQC 714
C++ G C+ SG C
Sbjct: 394 CSVPCECPE-GLCHPVSGSC 412
Score = 100 bits (239), Expect = 1e-19
Identities = 92/319 (28%), Positives = 123/319 (38%), Gaps = 67/319 (21%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
PC C PH G C+ +G C C P + C +PC CN T C
Sbjct: 132 PCACGPH---GRCDPATGVCHCEPGWWSSTCR------------RPCQCN---TAAARCE 173
Query: 420 PTDGLCPCKYNYAGKSCEI-----------------CEDGYYSPEC-KNCECNTVGSVSY 461
G C CK + G+ C C G++ PEC + CEC V
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRG 228
Query: 462 VCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC-ICK 519
C +G+CTC + G C C AG + C EP C +G C C+
Sbjct: 229 RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG-RCKHNEP--CSPDTGSCESCE 285
Query: 520 AGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKC-NCLTNFGGAQ 576
G+ G +C Q CL G + + E+QC C +C D G C C + G +
Sbjct: 286 PGWNGTQCQQPCLPGTFGE--SCEQQCPHCR------HGEACEPDTGHCQRCDPGWLGPR 337
Query: 577 C-DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C D C G + DC S C V GS CD G C C + + G C+ +C F+
Sbjct: 338 CEDPCPTGTFG-EDCGSTCPTCVQGS----CDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392
Query: 633 PACEECNCDPRGVTASFAG 651
C C P G+ +G
Sbjct: 393 NCSVPCEC-PEGLCHPVSG 410
Score = 98.7 bits (235), Expect = 3e-19
Identities = 84/275 (30%), Positives = 111/275 (40%), Gaps = 42/275 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSPC---EQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCV-CRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCR 1996
C+ TG C C PG +G +C D C +G + G C C G CD G C
Sbjct: 319 -CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG------SCDTVTGDCV 371
Query: 1997 CAKGVTGKQCD-QCAAGFWNYTKDGCD-HCNCNTG 2029
C+ G G C+ C AGF + C C C G
Sbjct: 372 CSAGYWGPSCNASCPAGFHG---NNCSVPCECPEG 403
Score = 89.0 bits (211), Expect = 3e-16
Identities = 101/358 (28%), Positives = 138/358 (38%), Gaps = 63/358 (17%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSIC 509
CE VC K G C CK + G C+ G Y P C+ C C G C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----C 111
Query: 510 DDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGR-ERQCVPCNCDPTGSTSTSCSADGKCN 567
+ +G C C+A G RC+ C G + GR + C+C+P G S++C C
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPH----GRCDPATGVCHCEP-GWWSSTCRRP--CQ 164
Query: 568 CLTNFGGAQCDQ------CSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGA 620
C N A+C+Q C PG++ CNC GS C+ D+G C C+ + G
Sbjct: 165 C--NTAAARCEQATGACVCKPGWWGRRCSFRCNCH-----GSPCEQDSGRCACRPGWWGP 217
Query: 621 KCDTCREQFYNY--PACEECNCDP--RGVTASF---AGCGSVPAGELC-QCKDRV----Q 668
+C E A EC C P RG AG V C +CK
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQHVGERQ 724
C C+P WN + C+Q C L GT +C + C C+ G
Sbjct: 278 TGSCESCEP-GWNGTQ-----CQQ-PC-LPGTFGE--SCEQQCPHCRHGEACEPDTGH-- 325
Query: 725 CDQCLDGFYRLQTND-----VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C +C G+ + D FG +C + +CD TG C C + G C+
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG-EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382
Score = 85.0 bits (201), Expect = 5e-15
Identities = 104/388 (26%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH------TTECTYDPEI 306
+CRC+ G C+ C G Q W E C CH H T C +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPHGQCEPATGACQCQADR 124
Query: 307 DEKRLSLDI----NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELD---VCQ 359
R +GR + +C+ C RP R ++ VC+
Sbjct: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCR--RPCQCNTAAARCEQATGACVCK 182
Query: 360 P------C--QCDPHFSTGNCEEESGRCECRPEFQPPDCSS---CAYGYFDYPN----CK 404
P C +C+ H S CE++SGRC CRP + P+C C G + C
Sbjct: 183 PGWWGRRCSFRCNCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 405 P----CTCNLN---GTEGEHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECKN-CE 452
P C L G+ G C + G C PC + SCE CE G+ +C+ C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCEPGWNGTQCQQPCL 298
Query: 453 CNTVG-SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK-PCNCDTSGTE----- 505
T G S C C+ +G C +C G+ P C+ PC T G +
Sbjct: 299 PGTFGESCEQQCPHCRHGEACEPD-TGH-CQRCDPGWLG-PRCEDPCPTGTFGEDCGSTC 355
Query: 506 PSI----CDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-------VPCNCDP- 552
P+ CD V+G C+C AG+ GP C+ C +G++ +C V +C P
Sbjct: 356 PTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPG 415
Query: 553 TGSTSTSCSADGKCNCLTNFGGAQCDQC 580
+GS T+ L F G C C
Sbjct: 416 SGSRDTALIVGSLVPLLLLFLGLACCAC 443
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 70.9 bits (166), Expect = 8e-11
Identities = 65/234 (27%), Positives = 81/234 (34%), Gaps = 43/234 (18%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 CY-CKTNVRGQAC-DTCKEEYFNLQDDNPDGCTKCF---CFGKTTRCSSSYYTW 1545
C C G C D C F +D C C C T C S W
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG--EDCGSTCPTCVQGSCDTVTGDCVCSAGYW 377
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 60.9 bits (141), Expect = 8e-08
Identities = 52/195 (26%), Positives = 66/195 (33%), Gaps = 20/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPC-HCPSTAICD-DNGMC-ICPKNVE 1407
C+ G+C C P G C C G +G C C C D G C C
Sbjct: 230 CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
Query: 1408 GENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVC-DH 1464
G C + C P TF ++ C C CE D+G C C G C D
Sbjct: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEA--------CEPDTGHCQRCDPGWLGPRCEDP 341
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNP 1523
C G + DC TC CD T C C G +C+ +C + P
Sbjct: 342 CPTGTFG-EDCGS-TCPT--CVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVP 397
Query: 1524 DGCTKCFCFGKTTRC 1538
C + C + C
Sbjct: 398 CECPEGLCHPVSGSC 412
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein.
Length = 830
Score = 107 bits (256), Expect = 1e-21
Identities = 105/359 (29%), Positives = 139/359 (38%), Gaps = 48/359 (13%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQC 1774
G D DE+ V+ C+C + G C G Y P C C C+ H QC
Sbjct: 59 GPDACQKDEVCVKPGL----CRCKPGFFGAHCSSRCPGQYWGPD--CRESCPCHPHG-QC 111
Query: 1775 DVNTGICLNCADNTIGDHCEF-CMSGYHG--DATVGTPR---DCLICACPMPYPSNNFAL 1828
+ TG C C + G CEF C G HG D G C P N A
Sbjct: 112 EPATGAC-QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP 1888
C+ + +C C+PG+ G RC + +G P + D C+P Q
Sbjct: 171 RCEQATG----ACVCKPGWWGRRCSF-RCNCHGSPCEQDSGRCA-CRPGWWGPECQQQCE 224
Query: 1889 ---GSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTT 1944
G C + +G+C C GA C L C G +G + +C C +E C T
Sbjct: 225 CVRGRCSAASGECT-CPPGFRGARCELPCPAGSHGVQC-AHSCGRCKHNE----PCSPDT 278
Query: 1945 GTCV-CRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
G+C C PG G +C + C P +G + C C G A C+ D G C RC G
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA-----CEPDTGHCQRCDPGW 333
Query: 2002 TGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCD-RCP 2057
G +C D C G + + C V C+ TG C C G G C+ CP
Sbjct: 334 LGPRCEDPCPTGTFG------EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 102 bits (244), Expect = 3e-20
Identities = 108/380 (28%), Positives = 148/380 (38%), Gaps = 82/380 (21%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNF----DGAKCDTCREQFYNYPACEE 637
PG+ C + G+ G +C+ HC+ D C C + P CE+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCRHGEACEPDTGHCQRCDPGWLG-PRCED 340
Query: 638 CNCDPRGVTASFAGCGSV-PAGELCQCKDRVQGRICNDCKPLYW--NLQEYNPFGCEQCN 694
C P G CGS P C D V G C YW + P G N
Sbjct: 341 -PC-PTGTFGE--DCGSTCPTCVQGSC-DTVTGDCV--CSAGYWGPSCNASCPAGFHGNN 393
Query: 695 CNLAGTLNSLGACNTKSGQC 714
C++ G C+ SG C
Sbjct: 394 CSVPCECPE-GLCHPVSGSC 412
Score = 100 bits (239), Expect = 1e-19
Identities = 92/319 (28%), Positives = 123/319 (38%), Gaps = 67/319 (21%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
PC C PH G C+ +G C C P + C +PC CN T C
Sbjct: 132 PCACGPH---GRCDPATGVCHCEPGWWSSTCR------------RPCQCN---TAAARCE 173
Query: 420 PTDGLCPCKYNYAGKSCEI-----------------CEDGYYSPEC-KNCECNTVGSVSY 461
G C CK + G+ C C G++ PEC + CEC V
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRG 228
Query: 462 VCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC-ICK 519
C +G+CTC + G C C AG + C EP C +G C C+
Sbjct: 229 RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG-RCKHNEP--CSPDTGSCESCE 285
Query: 520 AGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKC-NCLTNFGGAQ 576
G+ G +C Q CL G + + E+QC C +C D G C C + G +
Sbjct: 286 PGWNGTQCQQPCLPGTFGE--SCEQQCPHCR------HGEACEPDTGHCQRCDPGWLGPR 337
Query: 577 C-DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C D C G + DC S C V GS CD G C C + + G C+ +C F+
Sbjct: 338 CEDPCPTGTFG-EDCGSTCPTCVQGS----CDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392
Query: 633 PACEECNCDPRGVTASFAG 651
C C P G+ +G
Sbjct: 393 NCSVPCEC-PEGLCHPVSG 410
Score = 98.7 bits (235), Expect = 3e-19
Identities = 84/275 (30%), Positives = 111/275 (40%), Gaps = 42/275 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSPC---EQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCV-CRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCR 1996
C+ TG C C PG +G +C D C +G + G C C G CD G C
Sbjct: 319 -CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG------SCDTVTGDCV 371
Query: 1997 CAKGVTGKQCD-QCAAGFWNYTKDGCD-HCNCNTG 2029
C+ G G C+ C AGF + C C C G
Sbjct: 372 CSAGYWGPSCNASCPAGFHG---NNCSVPCECPEG 403
Score = 89.0 bits (211), Expect = 3e-16
Identities = 101/358 (28%), Positives = 138/358 (38%), Gaps = 63/358 (17%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSIC 509
CE VC K G C CK + G C+ G Y P C+ C C G C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----C 111
Query: 510 DDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGR-ERQCVPCNCDPTGSTSTSCSADGKCN 567
+ +G C C+A G RC+ C G + GR + C+C+P G S++C C
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPH----GRCDPATGVCHCEP-GWWSSTCRRP--CQ 164
Query: 568 CLTNFGGAQCDQ------CSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGA 620
C N A+C+Q C PG++ CNC GS C+ D+G C C+ + G
Sbjct: 165 C--NTAAARCEQATGACVCKPGWWGRRCSFRCNCH-----GSPCEQDSGRCACRPGWWGP 217
Query: 621 KCDTCREQFYNY--PACEECNCDP--RGVTASF---AGCGSVPAGELC-QCKDRV----Q 668
+C E A EC C P RG AG V C +CK
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQHVGERQ 724
C C+P WN + C+Q C L GT +C + C C+ G
Sbjct: 278 TGSCESCEP-GWNGTQ-----CQQ-PC-LPGTFGE--SCEQQCPHCRHGEACEPDTGH-- 325
Query: 725 CDQCLDGFYRLQTND-----VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C +C G+ + D FG +C + +CD TG C C + G C+
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG-EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382
Score = 85.0 bits (201), Expect = 5e-15
Identities = 104/388 (26%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH------TTECTYDPEI 306
+CRC+ G C+ C G Q W E C CH H T C +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPHGQCEPATGACQCQADR 124
Query: 307 DEKRLSLDI----NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELD---VCQ 359
R +GR + +C+ C RP R ++ VC+
Sbjct: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCR--RPCQCNTAAARCEQATGACVCK 182
Query: 360 P------C--QCDPHFSTGNCEEESGRCECRPEFQPPDCSS---CAYGYFDYPN----CK 404
P C +C+ H S CE++SGRC CRP + P+C C G + C
Sbjct: 183 PGWWGRRCSFRCNCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 405 P----CTCNLN---GTEGEHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECKN-CE 452
P C L G+ G C + G C PC + SCE CE G+ +C+ C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCEPGWNGTQCQQPCL 298
Query: 453 CNTVG-SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK-PCNCDTSGTE----- 505
T G S C C+ +G C +C G+ P C+ PC T G +
Sbjct: 299 PGTFGESCEQQCPHCRHGEACEPD-TGH-CQRCDPGWLG-PRCEDPCPTGTFGEDCGSTC 355
Query: 506 PSI----CDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-------VPCNCDP- 552
P+ CD V+G C+C AG+ GP C+ C +G++ +C V +C P
Sbjct: 356 PTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPG 415
Query: 553 TGSTSTSCSADGKCNCLTNFGGAQCDQC 580
+GS T+ L F G C C
Sbjct: 416 SGSRDTALIVGSLVPLLLLFLGLACCAC 443
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 70.9 bits (166), Expect = 8e-11
Identities = 65/234 (27%), Positives = 81/234 (34%), Gaps = 43/234 (18%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 CY-CKTNVRGQAC-DTCKEEYFNLQDDNPDGCTKCF---CFGKTTRCSSSYYTW 1545
C C G C D C F +D C C C T C S W
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG--EDCGSTCPTCVQGSCDTVTGDCVCSAGYW 377
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 60.9 bits (141), Expect = 8e-08
Identities = 52/195 (26%), Positives = 66/195 (33%), Gaps = 20/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPC-HCPSTAICD-DNGMC-ICPKNVE 1407
C+ G+C C P G C C G +G C C C D G C C
Sbjct: 230 CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
Query: 1408 GENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVC-DH 1464
G C + C P TF ++ C C CE D+G C C G C D
Sbjct: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEA--------CEPDTGHCQRCDPGWLGPRCEDP 341
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNP 1523
C G + DC TC CD T C C G +C+ +C + P
Sbjct: 342 CPTGTFG-EDCGS-TCPT--CVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVP 397
Query: 1524 DGCTKCFCFGKTTRC 1538
C + C + C
Sbjct: 398 CECPEGLCHPVSGSC 412
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor class F,
member 1 protein.
Length = 830
Score = 107 bits (256), Expect = 1e-21
Identities = 105/359 (29%), Positives = 139/359 (38%), Gaps = 48/359 (13%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQC 1774
G D DE+ V+ C+C + G C G Y P C C C+ H QC
Sbjct: 59 GPDACQKDEVCVKPGL----CRCKPGFFGAHCSSRCPGQYWGPD--CRESCPCHPHG-QC 111
Query: 1775 DVNTGICLNCADNTIGDHCEF-CMSGYHG--DATVGTPR---DCLICACPMPYPSNNFAL 1828
+ TG C C + G CEF C G HG D G C P N A
Sbjct: 112 EPATGAC-QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP 1888
C+ + +C C+PG+ G RC + +G P + D C+P Q
Sbjct: 171 RCEQATG----ACVCKPGWWGRRCSF-RCNCHGSPCEQDSGRCA-CRPGWWGPECQQQCE 224
Query: 1889 ---GSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTT 1944
G C + +G+C C GA C L C G +G + +C C +E C T
Sbjct: 225 CVRGRCSAASGECT-CPPGFRGARCELPCPAGSHGVQC-AHSCGRCKHNE----PCSPDT 278
Query: 1945 GTCV-CRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
G+C C PG G +C + C P +G + C C G A C+ D G C RC G
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA-----CEPDTGHCQRCDPGW 333
Query: 2002 TGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCD-RCP 2057
G +C D C G + + C V C+ TG C C G G C+ CP
Sbjct: 334 LGPRCEDPCPTGTFG------EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 102 bits (244), Expect = 3e-20
Identities = 108/380 (28%), Positives = 148/380 (38%), Gaps = 82/380 (21%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNF----DGAKCDTCREQFYNYPACEE 637
PG+ C + G+ G +C+ HC+ D C C + P CE+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCRHGEACEPDTGHCQRCDPGWLG-PRCED 340
Query: 638 CNCDPRGVTASFAGCGSV-PAGELCQCKDRVQGRICNDCKPLYW--NLQEYNPFGCEQCN 694
C P G CGS P C D V G C YW + P G N
Sbjct: 341 -PC-PTGTFGE--DCGSTCPTCVQGSC-DTVTGDCV--CSAGYWGPSCNASCPAGFHGNN 393
Query: 695 CNLAGTLNSLGACNTKSGQC 714
C++ G C+ SG C
Sbjct: 394 CSVPCECPE-GLCHPVSGSC 412
Score = 100 bits (239), Expect = 1e-19
Identities = 92/319 (28%), Positives = 123/319 (38%), Gaps = 67/319 (21%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
PC C PH G C+ +G C C P + C +PC CN T C
Sbjct: 132 PCACGPH---GRCDPATGVCHCEPGWWSSTCR------------RPCQCN---TAAARCE 173
Query: 420 PTDGLCPCKYNYAGKSCEI-----------------CEDGYYSPEC-KNCECNTVGSVSY 461
G C CK + G+ C C G++ PEC + CEC V
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRG 228
Query: 462 VCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC-ICK 519
C +G+CTC + G C C AG + C EP C +G C C+
Sbjct: 229 RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG-RCKHNEP--CSPDTGSCESCE 285
Query: 520 AGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKC-NCLTNFGGAQ 576
G+ G +C Q CL G + + E+QC C +C D G C C + G +
Sbjct: 286 PGWNGTQCQQPCLPGTFGE--SCEQQCPHCR------HGEACEPDTGHCQRCDPGWLGPR 337
Query: 577 C-DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C D C G + DC S C V GS CD G C C + + G C+ +C F+
Sbjct: 338 CEDPCPTGTFG-EDCGSTCPTCVQGS----CDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392
Query: 633 PACEECNCDPRGVTASFAG 651
C C P G+ +G
Sbjct: 393 NCSVPCEC-PEGLCHPVSG 410
Score = 98.7 bits (235), Expect = 3e-19
Identities = 84/275 (30%), Positives = 111/275 (40%), Gaps = 42/275 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSPC---EQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCV-CRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCR 1996
C+ TG C C PG +G +C D C +G + G C C G CD G C
Sbjct: 319 -CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG------SCDTVTGDCV 371
Query: 1997 CAKGVTGKQCD-QCAAGFWNYTKDGCD-HCNCNTG 2029
C+ G G C+ C AGF + C C C G
Sbjct: 372 CSAGYWGPSCNASCPAGFHG---NNCSVPCECPEG 403
Score = 89.0 bits (211), Expect = 3e-16
Identities = 101/358 (28%), Positives = 138/358 (38%), Gaps = 63/358 (17%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSIC 509
CE VC K G C CK + G C+ G Y P C+ C C G C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----C 111
Query: 510 DDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGR-ERQCVPCNCDPTGSTSTSCSADGKCN 567
+ +G C C+A G RC+ C G + GR + C+C+P G S++C C
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPH----GRCDPATGVCHCEP-GWWSSTCRRP--CQ 164
Query: 568 CLTNFGGAQCDQ------CSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGA 620
C N A+C+Q C PG++ CNC GS C+ D+G C C+ + G
Sbjct: 165 C--NTAAARCEQATGACVCKPGWWGRRCSFRCNCH-----GSPCEQDSGRCACRPGWWGP 217
Query: 621 KCDTCREQFYNY--PACEECNCDP--RGVTASF---AGCGSVPAGELC-QCKDRV----Q 668
+C E A EC C P RG AG V C +CK
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQHVGERQ 724
C C+P WN + C+Q C L GT +C + C C+ G
Sbjct: 278 TGSCESCEP-GWNGTQ-----CQQ-PC-LPGTFGE--SCEQQCPHCRHGEACEPDTGH-- 325
Query: 725 CDQCLDGFYRLQTND-----VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C +C G+ + D FG +C + +CD TG C C + G C+
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG-EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382
Score = 85.0 bits (201), Expect = 5e-15
Identities = 104/388 (26%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH------TTECTYDPEI 306
+CRC+ G C+ C G Q W E C CH H T C +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPHGQCEPATGACQCQADR 124
Query: 307 DEKRLSLDI----NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELD---VCQ 359
R +GR + +C+ C RP R ++ VC+
Sbjct: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCR--RPCQCNTAAARCEQATGACVCK 182
Query: 360 P------C--QCDPHFSTGNCEEESGRCECRPEFQPPDCSS---CAYGYFDYPN----CK 404
P C +C+ H S CE++SGRC CRP + P+C C G + C
Sbjct: 183 PGWWGRRCSFRCNCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 405 P----CTCNLN---GTEGEHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECKN-CE 452
P C L G+ G C + G C PC + SCE CE G+ +C+ C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCEPGWNGTQCQQPCL 298
Query: 453 CNTVG-SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK-PCNCDTSGTE----- 505
T G S C C+ +G C +C G+ P C+ PC T G +
Sbjct: 299 PGTFGESCEQQCPHCRHGEACEPD-TGH-CQRCDPGWLG-PRCEDPCPTGTFGEDCGSTC 355
Query: 506 PSI----CDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-------VPCNCDP- 552
P+ CD V+G C+C AG+ GP C+ C +G++ +C V +C P
Sbjct: 356 PTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPG 415
Query: 553 TGSTSTSCSADGKCNCLTNFGGAQCDQC 580
+GS T+ L F G C C
Sbjct: 416 SGSRDTALIVGSLVPLLLLFLGLACCAC 443
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 70.9 bits (166), Expect = 8e-11
Identities = 65/234 (27%), Positives = 81/234 (34%), Gaps = 43/234 (18%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 CY-CKTNVRGQAC-DTCKEEYFNLQDDNPDGCTKCF---CFGKTTRCSSSYYTW 1545
C C G C D C F +D C C C T C S W
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG--EDCGSTCPTCVQGSCDTVTGDCVCSAGYW 377
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 60.9 bits (141), Expect = 8e-08
Identities = 52/195 (26%), Positives = 66/195 (33%), Gaps = 20/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPC-HCPSTAICD-DNGMC-ICPKNVE 1407
C+ G+C C P G C C G +G C C C D G C C
Sbjct: 230 CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
Query: 1408 GENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVC-DH 1464
G C + C P TF ++ C C CE D+G C C G C D
Sbjct: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEA--------CEPDTGHCQRCDPGWLGPRCEDP 341
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNP 1523
C G + DC TC CD T C C G +C+ +C + P
Sbjct: 342 CPTGTFG-EDCGS-TCPT--CVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVP 397
Query: 1524 DGCTKCFCFGKTTRC 1538
C + C + C
Sbjct: 398 CECPEGLCHPVSGSC 412
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein.
Length = 569
Score = 107 bits (256), Expect = 1e-21
Identities = 105/359 (29%), Positives = 139/359 (38%), Gaps = 48/359 (13%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQC 1774
G D DE+ V+ C+C + G C G Y P C C C+ H QC
Sbjct: 59 GPDACQKDEVCVKPGL----CRCKPGFFGAHCSSRCPGQYWGPD--CRESCPCHPHG-QC 111
Query: 1775 DVNTGICLNCADNTIGDHCEF-CMSGYHG--DATVGTPR---DCLICACPMPYPSNNFAL 1828
+ TG C C + G CEF C G HG D G C P N A
Sbjct: 112 EPATGAC-QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP 1888
C+ + +C C+PG+ G RC + +G P + D C+P Q
Sbjct: 171 RCEQATG----ACVCKPGWWGRRCSF-RCNCHGSPCEQDSGRCA-CRPGWWGPECQQQCE 224
Query: 1889 ---GSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTT 1944
G C + +G+C C GA C L C G +G + +C C +E C T
Sbjct: 225 CVRGRCSAASGECT-CPPGFRGARCELPCPAGSHGVQC-AHSCGRCKHNE----PCSPDT 278
Query: 1945 GTCV-CRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
G+C C PG G +C + C P +G + C C G A C+ D G C RC G
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA-----CEPDTGHCQRCDPGW 333
Query: 2002 TGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCD-RCP 2057
G +C D C G + + C V C+ TG C C G G C+ CP
Sbjct: 334 LGPRCEDPCPTGTFG------EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 102 bits (244), Expect = 3e-20
Identities = 108/380 (28%), Positives = 148/380 (38%), Gaps = 82/380 (21%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNF----DGAKCDTCREQFYNYPACEE 637
PG+ C + G+ G +C+ HC+ D C C + P CE+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCRHGEACEPDTGHCQRCDPGWLG-PRCED 340
Query: 638 CNCDPRGVTASFAGCGSV-PAGELCQCKDRVQGRICNDCKPLYW--NLQEYNPFGCEQCN 694
C P G CGS P C D V G C YW + P G N
Sbjct: 341 -PC-PTGTFGE--DCGSTCPTCVQGSC-DTVTGDCV--CSAGYWGPSCNASCPAGFHGNN 393
Query: 695 CNLAGTLNSLGACNTKSGQC 714
C++ G C+ SG C
Sbjct: 394 CSVPCECPE-GLCHPVSGSC 412
Score = 100 bits (239), Expect = 1e-19
Identities = 92/319 (28%), Positives = 123/319 (38%), Gaps = 67/319 (21%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
PC C PH G C+ +G C C P + C +PC CN T C
Sbjct: 132 PCACGPH---GRCDPATGVCHCEPGWWSSTCR------------RPCQCN---TAAARCE 173
Query: 420 PTDGLCPCKYNYAGKSCEI-----------------CEDGYYSPEC-KNCECNTVGSVSY 461
G C CK + G+ C C G++ PEC + CEC V
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRG 228
Query: 462 VCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC-ICK 519
C +G+CTC + G C C AG + C EP C +G C C+
Sbjct: 229 RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG-RCKHNEP--CSPDTGSCESCE 285
Query: 520 AGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKC-NCLTNFGGAQ 576
G+ G +C Q CL G + + E+QC C +C D G C C + G +
Sbjct: 286 PGWNGTQCQQPCLPGTFGE--SCEQQCPHCR------HGEACEPDTGHCQRCDPGWLGPR 337
Query: 577 C-DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C D C G + DC S C V GS CD G C C + + G C+ +C F+
Sbjct: 338 CEDPCPTGTFG-EDCGSTCPTCVQGS----CDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392
Query: 633 PACEECNCDPRGVTASFAG 651
C C P G+ +G
Sbjct: 393 NCSVPCEC-PEGLCHPVSG 410
Score = 98.7 bits (235), Expect = 3e-19
Identities = 84/275 (30%), Positives = 111/275 (40%), Gaps = 42/275 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSPC---EQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCV-CRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCR 1996
C+ TG C C PG +G +C D C +G + G C C G CD G C
Sbjct: 319 -CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG------SCDTVTGDCV 371
Query: 1997 CAKGVTGKQCD-QCAAGFWNYTKDGCD-HCNCNTG 2029
C+ G G C+ C AGF + C C C G
Sbjct: 372 CSAGYWGPSCNASCPAGFHG---NNCSVPCECPEG 403
Score = 89.0 bits (211), Expect = 3e-16
Identities = 101/358 (28%), Positives = 138/358 (38%), Gaps = 63/358 (17%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSIC 509
CE VC K G C CK + G C+ G Y P C+ C C G C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----C 111
Query: 510 DDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGR-ERQCVPCNCDPTGSTSTSCSADGKCN 567
+ +G C C+A G RC+ C G + GR + C+C+P G S++C C
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPH----GRCDPATGVCHCEP-GWWSSTCRRP--CQ 164
Query: 568 CLTNFGGAQCDQ------CSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGA 620
C N A+C+Q C PG++ CNC GS C+ D+G C C+ + G
Sbjct: 165 C--NTAAARCEQATGACVCKPGWWGRRCSFRCNCH-----GSPCEQDSGRCACRPGWWGP 217
Query: 621 KCDTCREQFYNY--PACEECNCDP--RGVTASF---AGCGSVPAGELC-QCKDRV----Q 668
+C E A EC C P RG AG V C +CK
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQHVGERQ 724
C C+P WN + C+Q C L GT +C + C C+ G
Sbjct: 278 TGSCESCEP-GWNGTQ-----CQQ-PC-LPGTFGE--SCEQQCPHCRHGEACEPDTGH-- 325
Query: 725 CDQCLDGFYRLQTND-----VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C +C G+ + D FG +C + +CD TG C C + G C+
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG-EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382
Score = 85.0 bits (201), Expect = 5e-15
Identities = 104/388 (26%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH------TTECTYDPEI 306
+CRC+ G C+ C G Q W E C CH H T C +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPHGQCEPATGACQCQADR 124
Query: 307 DEKRLSLDI----NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELD---VCQ 359
R +GR + +C+ C RP R ++ VC+
Sbjct: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCR--RPCQCNTAAARCEQATGACVCK 182
Query: 360 P------C--QCDPHFSTGNCEEESGRCECRPEFQPPDCSS---CAYGYFDYPN----CK 404
P C +C+ H S CE++SGRC CRP + P+C C G + C
Sbjct: 183 PGWWGRRCSFRCNCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 405 P----CTCNLN---GTEGEHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECKN-CE 452
P C L G+ G C + G C PC + SCE CE G+ +C+ C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCEPGWNGTQCQQPCL 298
Query: 453 CNTVG-SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK-PCNCDTSGTE----- 505
T G S C C+ +G C +C G+ P C+ PC T G +
Sbjct: 299 PGTFGESCEQQCPHCRHGEACEPD-TGH-CQRCDPGWLG-PRCEDPCPTGTFGEDCGSTC 355
Query: 506 PSI----CDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-------VPCNCDP- 552
P+ CD V+G C+C AG+ GP C+ C +G++ +C V +C P
Sbjct: 356 PTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPG 415
Query: 553 TGSTSTSCSADGKCNCLTNFGGAQCDQC 580
+GS T+ L F G C C
Sbjct: 416 SGSRDTALIVGSLVPLLLLFLGLACCAC 443
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 70.9 bits (166), Expect = 8e-11
Identities = 65/234 (27%), Positives = 81/234 (34%), Gaps = 43/234 (18%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 CY-CKTNVRGQAC-DTCKEEYFNLQDDNPDGCTKCF---CFGKTTRCSSSYYTW 1545
C C G C D C F +D C C C T C S W
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG--EDCGSTCPTCVQGSCDTVTGDCVCSAGYW 377
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 60.9 bits (141), Expect = 8e-08
Identities = 52/195 (26%), Positives = 66/195 (33%), Gaps = 20/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPC-HCPSTAICD-DNGMC-ICPKNVE 1407
C+ G+C C P G C C G +G C C C D G C C
Sbjct: 230 CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
Query: 1408 GENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVC-DH 1464
G C + C P TF ++ C C CE D+G C C G C D
Sbjct: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEA--------CEPDTGHCQRCDPGWLGPRCEDP 341
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNP 1523
C G + DC TC CD T C C G +C+ +C + P
Sbjct: 342 CPTGTFG-EDCGS-TCPT--CVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVP 397
Query: 1524 DGCTKCFCFGKTTRC 1538
C + C + C
Sbjct: 398 CECPEGLCHPVSGSC 412
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein.
Length = 830
Score = 107 bits (256), Expect = 1e-21
Identities = 105/359 (29%), Positives = 139/359 (38%), Gaps = 48/359 (13%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQC 1774
G D DE+ V+ C+C + G C G Y P C C C+ H QC
Sbjct: 59 GPDACQKDEVCVKPGL----CRCKPGFFGAHCSSRCPGQYWGPD--CRESCPCHPHG-QC 111
Query: 1775 DVNTGICLNCADNTIGDHCEF-CMSGYHG--DATVGTPR---DCLICACPMPYPSNNFAL 1828
+ TG C C + G CEF C G HG D G C P N A
Sbjct: 112 EPATGAC-QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 1829 SCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP 1888
C+ + +C C+PG+ G RC + +G P + D C+P Q
Sbjct: 171 RCEQATG----ACVCKPGWWGRRCSF-RCNCHGSPCEQDSGRCA-CRPGWWGPECQQQCE 224
Query: 1889 ---GSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTT 1944
G C + +G+C C GA C L C G +G + +C C +E C T
Sbjct: 225 CVRGRCSAASGECT-CPPGFRGARCELPCPAGSHGVQC-AHSCGRCKHNE----PCSPDT 278
Query: 1945 GTCV-CRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC-RCAKGV 2001
G+C C PG G +C + C P +G + C C G A C+ D G C RC G
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA-----CEPDTGHCQRCDPGW 333
Query: 2002 TGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCD-RCP 2057
G +C D C G + + C V C+ TG C C G G C+ CP
Sbjct: 334 LGPRCEDPCPTGTFG------EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 102 bits (244), Expect = 3e-20
Identities = 108/380 (28%), Positives = 148/380 (38%), Gaps = 82/380 (21%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNF----DGAKCDTCREQFYNYPACEE 637
PG+ C + G+ G +C+ HC+ D C C + P CE+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCRHGEACEPDTGHCQRCDPGWLG-PRCED 340
Query: 638 CNCDPRGVTASFAGCGSV-PAGELCQCKDRVQGRICNDCKPLYW--NLQEYNPFGCEQCN 694
C P G CGS P C D V G C YW + P G N
Sbjct: 341 -PC-PTGTFGE--DCGSTCPTCVQGSC-DTVTGDCV--CSAGYWGPSCNASCPAGFHGNN 393
Query: 695 CNLAGTLNSLGACNTKSGQC 714
C++ G C+ SG C
Sbjct: 394 CSVPCECPE-GLCHPVSGSC 412
Score = 100 bits (239), Expect = 1e-19
Identities = 92/319 (28%), Positives = 123/319 (38%), Gaps = 67/319 (21%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
PC C PH G C+ +G C C P + C +PC CN T C
Sbjct: 132 PCACGPH---GRCDPATGVCHCEPGWWSSTCR------------RPCQCN---TAAARCE 173
Query: 420 PTDGLCPCKYNYAGKSCEI-----------------CEDGYYSPEC-KNCECNTVGSVSY 461
G C CK + G+ C C G++ PEC + CEC V
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRG 228
Query: 462 VCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC-ICK 519
C +G+CTC + G C C AG + C EP C +G C C+
Sbjct: 229 RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG-RCKHNEP--CSPDTGSCESCE 285
Query: 520 AGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKC-NCLTNFGGAQ 576
G+ G +C Q CL G + + E+QC C +C D G C C + G +
Sbjct: 286 PGWNGTQCQQPCLPGTFGE--SCEQQCPHCR------HGEACEPDTGHCQRCDPGWLGPR 337
Query: 577 C-DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCD-TCREQFYNY 632
C D C G + DC S C V GS CD G C C + + G C+ +C F+
Sbjct: 338 CEDPCPTGTFG-EDCGSTCPTCVQGS----CDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392
Query: 633 PACEECNCDPRGVTASFAG 651
C C P G+ +G
Sbjct: 393 NCSVPCEC-PEGLCHPVSG 410
Score = 98.7 bits (235), Expect = 3e-19
Identities = 84/275 (30%), Positives = 111/275 (40%), Gaps = 42/275 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSPC---EQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCV-CRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCR 1996
C+ TG C C PG +G +C D C +G + G C C G CD G C
Sbjct: 319 -CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG------SCDTVTGDCV 371
Query: 1997 CAKGVTGKQCD-QCAAGFWNYTKDGCD-HCNCNTG 2029
C+ G G C+ C AGF + C C C G
Sbjct: 372 CSAGYWGPSCNASCPAGFHG---NNCSVPCECPEG 403
Score = 89.0 bits (211), Expect = 3e-16
Identities = 101/358 (28%), Positives = 138/358 (38%), Gaps = 63/358 (17%)
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSIC 509
CE VC K G C CK + G C+ G Y P C+ C C G C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----C 111
Query: 510 DDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGR-ERQCVPCNCDPTGSTSTSCSADGKCN 567
+ +G C C+A G RC+ C G + GR + C+C+P G S++C C
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPH----GRCDPATGVCHCEP-GWWSSTCRRP--CQ 164
Query: 568 CLTNFGGAQCDQ------CSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKSNFDGA 620
C N A+C+Q C PG++ CNC GS C+ D+G C C+ + G
Sbjct: 165 C--NTAAARCEQATGACVCKPGWWGRRCSFRCNCH-----GSPCEQDSGRCACRPGWWGP 217
Query: 621 KCDTCREQFYNY--PACEECNCDP--RGVTASF---AGCGSVPAGELC-QCKDRV----Q 668
+C E A EC C P RG AG V C +CK
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 669 GRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQHVGERQ 724
C C+P WN + C+Q C L GT +C + C C+ G
Sbjct: 278 TGSCESCEP-GWNGTQ-----CQQ-PC-LPGTFGE--SCEQQCPHCRHGEACEPDTGH-- 325
Query: 725 CDQCLDGFYRLQTND-----VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C +C G+ + D FG +C + +CD TG C C + G C+
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG-EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382
Score = 85.0 bits (201), Expect = 5e-15
Identities = 104/388 (26%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNH------TTECTYDPEI 306
+CRC+ G C+ C G Q W E C CH H T C +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPHGQCEPATGACQCQADR 124
Query: 307 DEKRLSLDI----NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELD---VCQ 359
R +GR + +C+ C RP R ++ VC+
Sbjct: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCR--RPCQCNTAAARCEQATGACVCK 182
Query: 360 P------C--QCDPHFSTGNCEEESGRCECRPEFQPPDCSS---CAYGYFDYPN----CK 404
P C +C+ H S CE++SGRC CRP + P+C C G + C
Sbjct: 183 PGWWGRRCSFRCNCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 405 P----CTCNLN---GTEGEHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECKN-CE 452
P C L G+ G C + G C PC + SCE CE G+ +C+ C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCEPGWNGTQCQQPCL 298
Query: 453 CNTVG-SVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK-PCNCDTSGTE----- 505
T G S C C+ +G C +C G+ P C+ PC T G +
Sbjct: 299 PGTFGESCEQQCPHCRHGEACEPD-TGH-CQRCDPGWLG-PRCEDPCPTGTFGEDCGSTC 355
Query: 506 PSI----CDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-------VPCNCDP- 552
P+ CD V+G C+C AG+ GP C+ C +G++ +C V +C P
Sbjct: 356 PTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPG 415
Query: 553 TGSTSTSCSADGKCNCLTNFGGAQCDQC 580
+GS T+ L F G C C
Sbjct: 416 SGSRDTALIVGSLVPLLLLFLGLACCAC 443
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 70.9 bits (166), Expect = 8e-11
Identities = 65/234 (27%), Positives = 81/234 (34%), Gaps = 43/234 (18%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 CY-CKTNVRGQAC-DTCKEEYFNLQDDNPDGCTKCF---CFGKTTRCSSSYYTW 1545
C C G C D C F +D C C C T C S W
Sbjct: 326 CQRCDPGWLGPRCEDPCPTGTFG--EDCGSTCPTCVQGSCDTVTGDCVCSAGYW 377
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 60.9 bits (141), Expect = 8e-08
Identities = 52/195 (26%), Positives = 66/195 (33%), Gaps = 20/195 (10%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPC-HCPSTAICD-DNGMC-ICPKNVE 1407
C+ G+C C P G C C G +G C C C D G C C
Sbjct: 230 CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
Query: 1408 GENCDR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVC-DH 1464
G C + C P TF ++ C C CE D+G C C G C D
Sbjct: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEA--------CEPDTGHCQRCDPGWLGPRCEDP 341
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD-TCKEEYFNLQDDNP 1523
C G + DC TC CD T C C G +C+ +C + P
Sbjct: 342 CPTGTFG-EDCGS-TCPT--CVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVP 397
Query: 1524 DGCTKCFCFGKTTRC 1538
C + C + C
Sbjct: 398 CECPEGLCHPVSGSC 412
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>AB010099-1|BAA31347.1| 94|Homo sapiens laminin alpha 5 chain
protein.
Length = 94
Score = 101 bits (242), Expect = 5e-20
Identities = 42/92 (45%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1410 NCDRCKPYTFNFDVQRGCDDCNCNPLGVVG-NQLQCEADSGKCACRENVRGRVCDHCVPG 1468
+C C+P TF GC++CNC+ G+ C+ DSG+C CR NV GR CD C PG
Sbjct: 3 DCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPG 62
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCK 1500
+ +P C C C+ GT VCD T QCYCK
Sbjct: 63 FHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCK 94
Score = 85.4 bits (202), Expect = 3e-15
Identities = 30/75 (40%), Positives = 44/75 (58%), Gaps = 3/75 (4%)
Query: 448 CKNCECNTVGSVSYV---CDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGT 504
C+ C C+ G CD +G C C+ +GR C+ C G++ YP C+PC+C +GT
Sbjct: 20 CEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGT 79
Query: 505 EPSICDDVSGQCICK 519
P +CD ++GQC CK
Sbjct: 80 APGVCDPLTGQCYCK 94
Score = 76.6 bits (180), Expect = 2e-12
Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 387 PPDCSSC---AYGYFDYPNCKPCTCNLNGTE---GEHCTPTDGLCPCKYNYAGKSCEICE 440
PPDC C +G C+ C C+ G + C G C C+ N G+ C+ C
Sbjct: 1 PPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCS 60
Query: 441 DGYYS-PECKNCECNTVGSVSYVCDKLTGDCTCK 473
G++ P C+ C+C+ G+ VCD LTG C CK
Sbjct: 61 PGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCK 94
Score = 76.6 bits (180), Expect = 2e-12
Identities = 36/92 (39%), Positives = 50/92 (54%), Gaps = 7/92 (7%)
Query: 1958 CDRCAPDHWGLNTGLGCTPCNC---GIAS-ESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
C C P +G + +GC CNC GI CD D+GQC+C VTG++CD C+ GF
Sbjct: 4 CLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGF 63
Query: 2014 WNYTKDGCDHCNCNTGYSVGFMCN-ATGQCEC 2044
Y + C C+C+ + +C+ TGQC C
Sbjct: 64 HGYPR--CRPCDCHEAGTAPGVCDPLTGQCYC 93
Score = 72.9 bits (171), Expect = 2e-11
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Query: 689 GCEQCNCNLAGTLNSLG-ACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
GCE+CNC+ G C+T SGQC C+ +V R+CD C GF+ C CD
Sbjct: 19 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRPCD 73
Query: 748 CDIGGSIDNNCDKTTGQCHC 767
C G+ CD TGQC+C
Sbjct: 74 CHEAGTAPGVCDPLTGQCYC 93
Score = 72.9 bits (171), Expect = 2e-11
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 8/75 (10%)
Query: 1336 GARPCLCDFMGSTELE---CNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHC---- 1388
G C C G EL C+T GQC C+PNV GR C C G++G+P CRPC C
Sbjct: 19 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAG 78
Query: 1389 PSTAICDD-NGMCIC 1402
+ +CD G C C
Sbjct: 79 TAPGVCDPLTGQCYC 93
Score = 72.5 bits (170), Expect = 3e-11
Identities = 31/75 (41%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 545 CVPCNCDPTGS---TSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS 600
C CNC G T +C D G+C C N G +CD CSPG++ YP C C+C +G+
Sbjct: 20 CEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGT 79
Query: 601 IGSTCDD-NGLCHCK 614
CD G C+CK
Sbjct: 80 APGVCDPLTGQCYCK 94
Score = 69.7 bits (163), Expect = 2e-10
Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 358 CQPCQCD----PHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGT 413
C+ C C + C+ +SG+C+CRP C +C+ G+ YP C+PC C+ GT
Sbjct: 20 CEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGT 79
Query: 414 EGEHCTPTDGLCPCK 428
C P G C CK
Sbjct: 80 APGVCDPLTGQCYCK 94
Score = 66.5 bits (155), Expect = 2e-09
Identities = 35/91 (38%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 1863 PEDTDLHTGDYCKPCNCSG-NINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDA 1921
P+ H C+ CNCSG I +CD+ +G C KC N G C+ C+PGF+G
Sbjct: 9 PQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHG-- 65
Query: 1922 IFSKNCTACICDEFGMAD--CDSTTGTCVCR 1950
C C C E G A CD TG C C+
Sbjct: 66 --YPRCRPCDCHEAGTAPGVCDPLTGQCYCK 94
Score = 62.1 bits (144), Expect = 4e-08
Identities = 33/95 (34%), Positives = 39/95 (41%), Gaps = 11/95 (11%)
Query: 577 CDQCSP---GYYKYPDCLSCNCDVSGS---IGSTCD-DNGLCHCKSNFDGAKCDTCREQF 629
C C P G + C CNC G TCD D+G C C+ N G +CDTC F
Sbjct: 4 CLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGF 63
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCK 664
+ YP C C+C G P C CK
Sbjct: 64 HGYPRCRPCDCHEAGTAPGVCD----PLTGQCYCK 94
Score = 62.1 bits (144), Expect = 4e-08
Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMAD-----CDSTTGTCVCRPGVIGEKCDRCAPD 1964
C LC P +G C C C G+ + CD+ +G C CRP V G +CD C+P
Sbjct: 4 CLLCQPQTFGCHPLV-GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPG 62
Query: 1965 HWGLNTGLGCTPCNCGIASEST-QCDDDNGQCRC 1997
G C PC+C A + CD GQC C
Sbjct: 63 FHGYPR---CRPCDCHEAGTAPGVCDPLTGQCYC 93
Score = 60.1 bits (139), Expect = 1e-07
Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 622 CDTCREQFYN-YP--ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
C C+ Q + +P CEECNC G+ +G+ C+C+ V GR C+ C P
Sbjct: 4 CLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQ-CKCRPNVTGRRCDTCSPG 62
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCK 717
+ C C+C+ AGT + G C+ +GQC CK
Sbjct: 63 FHGYPR-----CRPCDCHEAGT--APGVCDPLTGQCYCK 94
Score = 58.0 bits (134), Expect = 6e-07
Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
Query: 481 CNQCQAGYYNYPTCKPCNCDTSG----TEPSICDDVSGQCICKAGFGGPRCDQCLSGYYM 536
C G + C+ CNC G T+P+ CD SGQC C+ G RCD C G++
Sbjct: 7 CQPQTFGCHPLVGCEECNCSGPGIQELTDPT-CDTDSGQCKCRPNVTGRRCDTCSPGFH- 64
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNC 568
G R C PC+C G+ C G+C C
Sbjct: 65 ---GYPR-CRPCDCHEAGTAPGVCDPLTGQCYC 93
Score = 48.8 bits (111), Expect = 4e-04
Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 13/93 (13%)
Query: 1370 CSACRTGYYGFPNCRPCHCPSTAI-------CD-DNGMCICPKNVEGENCDRCKPYTFNF 1421
C G + C C+C I CD D+G C C NV G CD C P F
Sbjct: 7 CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSP---GF 63
Query: 1422 DVQRGCDDCNCNPLGVVGNQLQCEADSGKCACR 1454
C C+C+ G C+ +G+C C+
Sbjct: 64 HGYPRCRPCDCHEAGTAPG--VCDPLTGQCYCK 94
Score = 48.4 bits (110), Expect = 5e-04
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 15/87 (17%)
Query: 1812 CLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTG 1871
C C C P +CD +++G C C+P G RC+ C+ G++G P
Sbjct: 20 CEECNCSGPGIQELTDPTCD-TDSGQ---CKCRPNVTGRRCDTCSPGFHGYPR------- 68
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDC 1898
C+PC+C + PG CD + G C
Sbjct: 69 --CRPCDC--HEAGTAPGVCDPLTGQC 91
Score = 45.6 bits (103), Expect = 0.003
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 6/71 (8%)
Query: 1462 CDHCVP---GHYAFPDCYQCTCNRHGT---TYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C P G + C +C C+ G T CD ++ QC C+ NV G+ CDTC +
Sbjct: 4 CLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGF 63
Query: 1516 FNLQDDNPDGC 1526
P C
Sbjct: 64 HGYPRCRPCDC 74
Score = 44.0 bits (99), Expect = 0.010
Identities = 19/39 (48%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 742 GCTECDCDIGGS---IDNNCDKTTGQCHCHSRVEGRRCD 777
GC EC+C G D CD +GQC C V GRRCD
Sbjct: 19 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCD 57
Score = 42.3 bits (95), Expect = 0.032
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 9/63 (14%)
Query: 2020 GCDHCNCNTGYSVGFMCNAT-----GQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
GC+ CNC+ G + + + T GQC+C P V G +CD C + P+ C CD C
Sbjct: 19 GCEECNCS-GPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR--CRPCD-C 74
Query: 2075 TDA 2077
+A
Sbjct: 75 HEA 77
Score = 37.9 bits (84), Expect = 0.68
Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 22/96 (22%)
Query: 288 CEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRP 347
CE CNC + DP D G+C C+ N G C+ C P ++
Sbjct: 20 CEECNCSGPGIQELTDPTCD------------TDSGQC-KCRPNVTGRRCDTCSPGFH-G 65
Query: 348 YGKRWDELDVCQPCQC-DPHFSTGNCEEESGRCECR 382
Y + C+PC C + + G C+ +G+C C+
Sbjct: 66 YPR-------CRPCDCHEAGTAPGVCDPLTGQCYCK 94
Score = 37.9 bits (84), Expect = 0.68
Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 8/57 (14%)
Query: 1762 CVPCQCNGHSDQ------CDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDC 1812
C C C+G Q CD ++G C C N G C+ C G+HG P DC
Sbjct: 20 CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHGYPRC-RPCDC 74
Score = 36.3 bits (80), Expect = 2.1
Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 11/68 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C C+G E DP + + C+C+ N G +C+ C GF + R C P
Sbjct: 23 CNCSGPGIQ-ELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGF--------HGYPR--CRP 71
Query: 291 CNCHNHTT 298
C+CH T
Sbjct: 72 CDCHEAGT 79
>BC084578-1|AAH84578.1| 719|Homo sapiens AGRN protein protein.
Length = 719
Score = 95.5 bits (227), Expect = 3e-18
Identities = 73/257 (28%), Positives = 100/257 (38%), Gaps = 36/257 (14%)
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFST--GN--CEEESGRCECRPEFQPPDCSSCAY 395
C R G WDE PC CD + G+ C + E + C S
Sbjct: 164 CEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 223
Query: 396 GYFDYPN-CK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CE 452
Y C+ P L HC T C C+ N G C + C+
Sbjct: 224 LYVAAQGACRGPTFAPLPPVAPLHCAQTPYGC-CQDNITAAR------GVGLAGCPSACQ 276
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--------PTCKPCNCDTSGT 504
CN GS CD TG C+C+ G C++C+ G++N+ C PC+CD G
Sbjct: 277 CNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGA 336
Query: 505 EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
C+ ++G C CK G GP+C QC G + LG P C+ S +C A+
Sbjct: 337 VRDDCEQMTGLCSCKPGVAGPKCGQCPDG---RALG------PAGCEADASAPATC-AEM 386
Query: 565 KC----NCLTNFGGAQC 577
+C C+ G A C
Sbjct: 387 RCEFGARCVEESGSAHC 403
Score = 85.8 bits (203), Expect = 3e-15
Identities = 113/404 (27%), Positives = 153/404 (37%), Gaps = 73/404 (18%)
Query: 1721 MGDELVVRRATSVEEC-QCPRAYRGLSCEQCAEGHYRLPSGFCVP-----CQCNGHS--D 1772
+G E+ V R + C QC G CE G PS CV C +GH+
Sbjct: 4 LGREIQVARKGPCDRCGQCRF---GALCE-AETGRCVCPSE-CVALAQPVCGSDGHTYPS 58
Query: 1773 QCDVNTGICLNCADNTIGDH--CEFCMSGYHGDATVGTPRDCLICACPMPYPSN------ 1824
+C ++ C + + CE C V + C+ C P P
Sbjct: 59 ECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDG 118
Query: 1825 -NFALSCDLSENGSLISCNCQPGYGGARCEY--CAAGYYGIPEDTDLHTGDYCKPCNCSG 1881
+ +C+L E L + G CE C +G G ED D + C G
Sbjct: 119 VTYGSACELREAACLQQTQIEEARAGP-CEQAECGSGGSGSGEDGDCEQ----ELCRQRG 173
Query: 1882 NINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCD 1941
I +D S +G C+ + + +C G G +S C E A C+
Sbjct: 174 GIWDED-----SEDGPCVCDFSCQSVPGSPVC--GSDG-VTYSTEC------ELKKARCE 219
Query: 1942 STTGTCV-----CR-------PGVIGEKCDR----CAPDHWGLNTGLG---C-TPCNCGI 1981
S G V CR P V C + C D+ G+G C + C C
Sbjct: 220 SQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNP 279
Query: 1982 -ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT------KDGCDHCNCNTGYSVGF 2034
S CD GQC C GV G +CD+C GFWN+ + GC C+C+ +V
Sbjct: 280 HGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRD 339
Query: 2035 MC-NATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
C TG C C PGV G KC +CP+ L P GC E D+ A
Sbjct: 340 DCEQMTGLCSCKPGVAGPKCGQCPDGRALGP-AGC-EADASAPA 381
Score = 79.4 bits (187), Expect = 2e-13
Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 6/94 (6%)
Query: 689 GCEQ-CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ---TNDVFGCT 744
GC C CN G+ G C+ +GQC C+ VG +CD+C GF+ + T+ GCT
Sbjct: 270 GCPSACQCNPHGSYG--GTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCT 327
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
C CD G++ ++C++ TG C C V G +C Q
Sbjct: 328 PCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQ 361
Score = 77.0 bits (181), Expect = 1e-12
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 23/180 (12%)
Query: 548 CNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKY--------PDCLSCNCDVS 598
C C+P GS +C A G+C+C GG +CD+C PG++ + C C+CD
Sbjct: 275 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 334
Query: 599 GSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF-----AGC 652
G++ C+ GLC CK G KC C + PA E + A A C
Sbjct: 335 GAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARC 394
Query: 653 GSVPAGELC-----QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
C C + ++C Y N + C Q L ++ SLG C
Sbjct: 395 VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQ---GLQISIQSLGPC 451
Score = 73.7 bits (173), Expect = 1e-11
Identities = 36/97 (37%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 1426 GCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--------PDCY 1476
GC C CNP G G C+ +G+C+CR V G CD C PG + F C
Sbjct: 270 GCPSACQCNPHGSYGGT--CDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCT 327
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE 1513
C+C+ G D C+Q T C CK V G C C +
Sbjct: 328 PCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPD 364
Score = 68.9 bits (161), Expect = 3e-10
Identities = 45/148 (30%), Positives = 63/148 (42%), Gaps = 12/148 (8%)
Query: 1376 GYYGFPNCRPC--HCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNF-----DVQRGC 1427
G G P+ C H CD G C C V G CDRC+P +NF D + GC
Sbjct: 267 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 326
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTY 1487
C+C+P G V + CE +G C+C+ V G C C G P + + T
Sbjct: 327 TPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCA 384
Query: 1488 DVCDQNTAQCYCKTNVRGQACD--TCKE 1513
++ + A+C ++ C TC E
Sbjct: 385 EMRCEFGARCVEESGSAHCVCPMLTCPE 412
Score = 68.5 bits (160), Expect = 4e-10
Identities = 98/387 (25%), Positives = 137/387 (35%), Gaps = 51/387 (13%)
Query: 372 CEEESGRCECRPE---FQPPDCSSCAYGYFD--YPNCKPCTCNLN---GTEGEHCTPTDG 423
CE E+GRC C E P C S + Y + CT ++ + G T D
Sbjct: 28 CEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDA 87
Query: 424 LCPC-KYNYAGKS-CEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
+C AG+ C CE P C + + T GS + + T + C
Sbjct: 88 VCAFGAVCSAGQCVCPRCEHPPPGPVCGS-DGVTYGSACELREAACLQQTQIEEARAGPC 146
Query: 482 NQCQAGYYNYPTCKPCNCDTS--GTEPSICDDVS--GQCICKAGF----GGPRCDQCLSG 533
Q + G + + +C+ I D+ S G C+C G P C
Sbjct: 147 EQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVT 206
Query: 534 YYMQVLGRERQC-------VPCNCDPTGSTSTSCSADGKCNCL-TNFGGAQCDQCSPGYY 585
Y + ++ +C V G T +C T +G Q + +
Sbjct: 207 YSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGV 266
Query: 586 KYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNY--------PAC 635
C S C C+ GS G TCD G C C+ G +CD C F+N+ C
Sbjct: 267 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 326
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCE---Q 692
C+CDP+G C + LC CK V G C C + + P GCE
Sbjct: 327 TPCSCDPQGAVRD--DCEQMTG--LCSCKPGVAGPKCGQCP----DGRALGPAGCEADAS 378
Query: 693 CNCNLAGTLNSLGA-CNTKSG--QCVC 716
A GA C +SG CVC
Sbjct: 379 APATCAEMRCEFGARCVEESGSAHCVC 405
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/393 (23%), Positives = 127/393 (32%), Gaps = 54/393 (13%)
Query: 415 GEHCTPTDGLCPCKYNYAGKSCEIC-EDGY-YSPECKNCECNTVGSVSYVCDKLTGDC-T 471
G C G C C + +C DG+ Y EC +S G C T
Sbjct: 25 GALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVAS-AGPCET 83
Query: 472 CKSKYS--GRTCN--QCQAGYYNYPTCKPCNCDTSG-TEPSICDDVSGQCICKAGFGGPR 526
C G C+ QC +P P C + G T S C+ C+ + R
Sbjct: 84 CGDAVCAFGAVCSAGQCVCPRCEHPPPGPV-CGSDGVTYGSACELREAACLQQTQIEEAR 142
Query: 527 ---CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC----NCLTNFGGAQCDQ 579
C+Q G G + C C G S DG C +C + G C
Sbjct: 143 AGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGS 202
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLC--------------HCKSNFDGAKCDTC 625
Y + C+ G G C HC G D
Sbjct: 203 DGVTYSTECELKKARCE--SQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNI 260
Query: 626 RE-QFYNYPACEE-CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ C C C+P G S+ G G+ C C+ V G C+ C+P +WN +
Sbjct: 261 TAARGVGLAGCPSACQCNPHG---SYGGTCDPATGQ-CSCRPGVGGLRCDRCEPGFWNFR 316
Query: 684 EY---NPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG------FYR 734
GC C+C+ G + C +G C CK V +C QC DG
Sbjct: 317 GIVTDGRSGCTPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCE 374
Query: 735 LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
+ C E C+ G C + +G HC
Sbjct: 375 ADASAPATCAEMRCEFGA----RCVEESGSAHC 403
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST-GNCEEESGRCEC 381
G+C +C+ G+ C++C P ++ G D C PC CDP + +CE+ +G C C
Sbjct: 292 GQC-SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSC 350
Query: 382 RPEFQPPDCSSCAYGYFDYP-NCK-----PCTC-NLNGTEGEHCTPTDG----LCPCKYN 430
+P P C C G P C+ P TC + G C G +CP
Sbjct: 351 KPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTC 410
Query: 431 YAGKSCEIC-EDGY-YSPECK 449
+ ++C DG Y EC+
Sbjct: 411 PEANATKVCGSDGVTYGNECQ 431
Score = 62.1 bits (144), Expect = 4e-08
Identities = 53/189 (28%), Positives = 71/189 (37%), Gaps = 25/189 (13%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--------PNCRPCHC-PS 1390
C C+ GS C+ GQC C+P V G C C G++ F C PC C P
Sbjct: 275 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 334
Query: 1391 TAICDD----NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
A+ DD G+C C V G C +C P GC+ P +++CE
Sbjct: 335 GAVRDDCEQMTGLCSCKPGVAGPKCGQC-PDGRALG-PAGCEADASAPATCA--EMRCEF 390
Query: 1447 DSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTY-DVCDQNTAQCYCKTNVR 1504
+C V HCV P+ C G TY + C T C +
Sbjct: 391 -GARC-----VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQIS 444
Query: 1505 GQACDTCKE 1513
Q+ C+E
Sbjct: 445 IQSLGPCQE 453
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/178 (29%), Positives = 73/178 (41%), Gaps = 28/178 (15%)
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
L+CA G C+ ++ G G P C C P ++ +CD + C
Sbjct: 246 LHCAQTPYGC-CQDNITAARGVGLAGCPS---ACQCN---PHGSYGGTCDPATG----QC 294
Query: 1842 NCQPGYGGARCEYCAAGYYGIPE-DTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
+C+PG GG RC+ C G++ TD +G C PC+C +D C+ + G C
Sbjct: 295 SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSG--CTPCSCDPQGAVRD--DCEQMTGLC-S 349
Query: 1901 CVNNTAGAACNLC-------APGFYGDAIFSKNCTACICDEFGMADCDSTTGT--CVC 1949
C AG C C G DA C C EFG A C +G+ CVC
Sbjct: 350 CKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRC-EFG-ARCVEESGSAHCVC 405
Score = 56.0 bits (129), Expect = 2e-06
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQ---DDNPDGCTKCFC 1531
C CN HG+ CD T QC C+ V G CD C+ ++N + D GCT C C
Sbjct: 275 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSC 331
Score = 47.6 bits (108), Expect = 8e-04
Identities = 19/48 (39%), Positives = 23/48 (47%)
Query: 1329 ITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTG 1376
I ++ SG PC CD G+ +C G C CKP V G C C G
Sbjct: 318 IVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG 365
Score = 39.9 bits (89), Expect = 0.17
Identities = 40/153 (26%), Positives = 56/153 (36%), Gaps = 26/153 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H DPA C C+ G +C++C GF + ++ R C P
Sbjct: 275 CQCNPHGSYGGTCDPATGQ----CSCRPGVGGLRCDRCEPGFWNFRGIVTDG--RSGCTP 328
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C DP+ + + + G C +C+ G C +C R G
Sbjct: 329 CSC---------DPQGAVR------DDCEQMTGLC-SCKPGVAGPKCGQCPDG--RALGP 370
Query: 351 RWDELDVCQPCQC-DPHFSTG-NCEEESGRCEC 381
E D P C + G C EESG C
Sbjct: 371 AGCEADASAPATCAEMRCEFGARCVEESGSAHC 403
>AL645608-12|CAI15575.2| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 95.5 bits (227), Expect = 3e-18
Identities = 73/257 (28%), Positives = 100/257 (38%), Gaps = 36/257 (14%)
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFST--GN--CEEESGRCECRPEFQPPDCSSCAY 395
C R G WDE PC CD + G+ C + E + C S
Sbjct: 682 CEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 741
Query: 396 GYFDYPN-CK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CE 452
Y C+ P L HC T C C+ N G C + C+
Sbjct: 742 LYVAAQGACRGPTFAPLPPVAPLHCAQTPYGC-CQDNITAAR------GVGLAGCPSACQ 794
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--------PTCKPCNCDTSGT 504
CN GS CD TG C+C+ G C++C+ G++N+ C PC+CD G
Sbjct: 795 CNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGA 854
Query: 505 EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
C+ ++G C CK G GP+C QC G + LG P C+ S +C A+
Sbjct: 855 VRDDCEQMTGLCSCKPGVAGPKCGQCPDG---RALG------PAGCEADASAPATC-AEM 904
Query: 565 KC----NCLTNFGGAQC 577
+C C+ G A C
Sbjct: 905 RCEFGARCVEESGSAHC 921
Score = 87.4 bits (207), Expect = 9e-16
Identities = 115/415 (27%), Positives = 154/415 (37%), Gaps = 74/415 (17%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCV-PCQC------ 1767
GV Y EL T E Q R C QC G +G CV P +C
Sbjct: 506 GVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQP 565
Query: 1768 ----NGHS--DQCDVNTGICLNCADNTIGDH--CEFCMSGYHGDATVGTPRDCLICACPM 1819
+GH+ +C ++ C + + CE C V + C+ C
Sbjct: 566 VCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEH 625
Query: 1820 PYPSN-------NFALSCDLSENGSLISCNCQPGYGGARCEY--CAAGYYGIPEDTDLHT 1870
P P + +C+L E L + G CE C +G G ED D
Sbjct: 626 PPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGP-CEQAECGSGGSGSGEDGDCEQ 684
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTAC 1930
+ C G I +D S +G C+ + + +C G G +S C
Sbjct: 685 ----ELCRQRGGIWDED-----SEDGPCVCDFSCQSVPGSPVC--GSDG-VTYSTEC--- 729
Query: 1931 ICDEFGMADCDSTTGTCV-----CR-------PGVIGEKCDR----CAPDHWGLNTGLG- 1973
E A C+S G V CR P V C + C D+ G+G
Sbjct: 730 ---ELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGL 786
Query: 1974 --C-TPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT------KDGCDH 2023
C + C C S CD GQC C GV G +CD+C GFWN+ + GC
Sbjct: 787 AGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTP 846
Query: 2024 CNCNTGYSVGFMC-NATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
C+C+ +V C TG C C PGV G KC +CP+ L P GC E D+ A
Sbjct: 847 CSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGP-AGC-EADASAPA 899
Score = 80.2 bits (189), Expect = 1e-13
Identities = 93/386 (24%), Positives = 141/386 (36%), Gaps = 56/386 (14%)
Query: 433 GKSCEI----CEDGYYSPECKNCECNTVGSVSY--VCDKLTGDCTCKSKYSGRTCNQCQA 486
G +CE+ C G + C+ G + +C+ TG C C S+ C +
Sbjct: 510 GSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGS 569
Query: 487 GYYNYPT-CK----PCN------------CDTSGTEPSICDDV--SGQCICKAGFGGPRC 527
+ YP+ C C C+T G V +GQC+C PRC
Sbjct: 570 DGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVC------PRC 623
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
+ G V G + C+ + + + A+C G +
Sbjct: 624 EHPPPG---PVCGSDGVTYGSACELREAACLQQTQIEEARA-GPCEQAECGSGGSGSGED 679
Query: 588 PDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAK-CDTCREQFYNYPA-CE--ECNCDP- 642
DC C G I ++G C C + C Y CE + C+
Sbjct: 680 GDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQ 739
Query: 643 RGVTASFAGC------GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ-CNC 695
RG+ + G +P C G C C+ + GC C C
Sbjct: 740 RGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYG--C--CQDNITAARGVGLAGCPSACQC 795
Query: 696 NLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ---TNDVFGCTECDCDIGG 752
N G+ G C+ +GQC C+ VG +CD+C GF+ + T+ GCT C CD G
Sbjct: 796 NPHGSYG--GTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQG 853
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQ 778
++ ++C++ TG C C V G +C Q
Sbjct: 854 AVRDDCEQMTGLCSCKPGVAGPKCGQ 879
Score = 77.0 bits (181), Expect = 1e-12
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 23/180 (12%)
Query: 548 CNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKY--------PDCLSCNCDVS 598
C C+P GS +C A G+C+C GG +CD+C PG++ + C C+CD
Sbjct: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 852
Query: 599 GSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF-----AGC 652
G++ C+ GLC CK G KC C + PA E + A A C
Sbjct: 853 GAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARC 912
Query: 653 GSVPAGELC-----QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
C C + ++C Y N + C Q L ++ SLG C
Sbjct: 913 VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQ---GLQISIQSLGPC 969
Score = 73.7 bits (173), Expect = 1e-11
Identities = 36/97 (37%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 1426 GCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--------PDCY 1476
GC C CNP G G C+ +G+C+CR V G CD C PG + F C
Sbjct: 788 GCPSACQCNPHGSYGGT--CDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCT 845
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE 1513
C+C+ G D C+Q T C CK V G C C +
Sbjct: 846 PCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPD 882
Score = 68.9 bits (161), Expect = 3e-10
Identities = 45/148 (30%), Positives = 63/148 (42%), Gaps = 12/148 (8%)
Query: 1376 GYYGFPNCRPC--HCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNF-----DVQRGC 1427
G G P+ C H CD G C C V G CDRC+P +NF D + GC
Sbjct: 785 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 844
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTY 1487
C+C+P G V + CE +G C+C+ V G C C G P + + T
Sbjct: 845 TPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCA 902
Query: 1488 DVCDQNTAQCYCKTNVRGQACD--TCKE 1513
++ + A+C ++ C TC E
Sbjct: 903 EMRCEFGARCVEESGSAHCVCPMLTCPE 930
Score = 68.5 bits (160), Expect = 4e-10
Identities = 98/387 (25%), Positives = 137/387 (35%), Gaps = 51/387 (13%)
Query: 372 CEEESGRCECRPE---FQPPDCSSCAYGYFD--YPNCKPCTCNLN---GTEGEHCTPTDG 423
CE E+GRC C E P C S + Y + CT ++ + G T D
Sbjct: 546 CEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDA 605
Query: 424 LCPC-KYNYAGKS-CEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
+C AG+ C CE P C + + T GS + + T + C
Sbjct: 606 VCAFGAVCSAGQCVCPRCEHPPPGPVCGS-DGVTYGSACELREAACLQQTQIEEARAGPC 664
Query: 482 NQCQAGYYNYPTCKPCNCDTS--GTEPSICDDVS--GQCICKAGF----GGPRCDQCLSG 533
Q + G + + +C+ I D+ S G C+C G P C
Sbjct: 665 EQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVT 724
Query: 534 YYMQVLGRERQC-------VPCNCDPTGSTSTSCSADGKCNCL-TNFGGAQCDQCSPGYY 585
Y + ++ +C V G T +C T +G Q + +
Sbjct: 725 YSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGV 784
Query: 586 KYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNY--------PAC 635
C S C C+ GS G TCD G C C+ G +CD C F+N+ C
Sbjct: 785 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 844
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCE---Q 692
C+CDP+G C + LC CK V G C C + + P GCE
Sbjct: 845 TPCSCDPQGAVRD--DCEQMTG--LCSCKPGVAGPKCGQCP----DGRALGPAGCEADAS 896
Query: 693 CNCNLAGTLNSLGA-CNTKSG--QCVC 716
A GA C +SG CVC
Sbjct: 897 APATCAEMRCEFGARCVEESGSAHCVC 923
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/393 (23%), Positives = 127/393 (32%), Gaps = 54/393 (13%)
Query: 415 GEHCTPTDGLCPCKYNYAGKSCEIC-EDGY-YSPECKNCECNTVGSVSYVCDKLTGDC-T 471
G C G C C + +C DG+ Y EC +S G C T
Sbjct: 543 GALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVAS-AGPCET 601
Query: 472 CKSKYS--GRTCN--QCQAGYYNYPTCKPCNCDTSG-TEPSICDDVSGQCICKAGFGGPR 526
C G C+ QC +P P C + G T S C+ C+ + R
Sbjct: 602 CGDAVCAFGAVCSAGQCVCPRCEHPPPGPV-CGSDGVTYGSACELREAACLQQTQIEEAR 660
Query: 527 ---CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC----NCLTNFGGAQCDQ 579
C+Q G G + C C G S DG C +C + G C
Sbjct: 661 AGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGS 720
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLC--------------HCKSNFDGAKCDTC 625
Y + C+ G G C HC G D
Sbjct: 721 DGVTYSTECELKKARCE--SQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNI 778
Query: 626 RE-QFYNYPACEE-CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ C C C+P G S+ G G+ C C+ V G C+ C+P +WN +
Sbjct: 779 TAARGVGLAGCPSACQCNPHG---SYGGTCDPATGQ-CSCRPGVGGLRCDRCEPGFWNFR 834
Query: 684 EY---NPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG------FYR 734
GC C+C+ G + C +G C CK V +C QC DG
Sbjct: 835 GIVTDGRSGCTPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCE 892
Query: 735 LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
+ C E C+ G C + +G HC
Sbjct: 893 ADASAPATCAEMRCEFGA----RCVEESGSAHC 921
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST-GNCEEESGRCEC 381
G+C +C+ G+ C++C P ++ G D C PC CDP + +CE+ +G C C
Sbjct: 810 GQC-SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSC 868
Query: 382 RPEFQPPDCSSCAYGYFDYP-NCK-----PCTC-NLNGTEGEHCTPTDG----LCPCKYN 430
+P P C C G P C+ P TC + G C G +CP
Sbjct: 869 KPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTC 928
Query: 431 YAGKSCEIC-EDGY-YSPECK 449
+ ++C DG Y EC+
Sbjct: 929 PEANATKVCGSDGVTYGNECQ 949
Score = 62.1 bits (144), Expect = 4e-08
Identities = 53/189 (28%), Positives = 71/189 (37%), Gaps = 25/189 (13%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--------PNCRPCHC-PS 1390
C C+ GS C+ GQC C+P V G C C G++ F C PC C P
Sbjct: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 852
Query: 1391 TAICDD----NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
A+ DD G+C C V G C +C P GC+ P +++CE
Sbjct: 853 GAVRDDCEQMTGLCSCKPGVAGPKCGQC-PDGRALG-PAGCEADASAPATCA--EMRCEF 908
Query: 1447 DSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTY-DVCDQNTAQCYCKTNVR 1504
+C V HCV P+ C G TY + C T C +
Sbjct: 909 -GARC-----VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQIS 962
Query: 1505 GQACDTCKE 1513
Q+ C+E
Sbjct: 963 IQSLGPCQE 971
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/178 (29%), Positives = 73/178 (41%), Gaps = 28/178 (15%)
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
L+CA G C+ ++ G G P C C P ++ +CD + C
Sbjct: 764 LHCAQTPYGC-CQDNITAARGVGLAGCPS---ACQCN---PHGSYGGTCDPATG----QC 812
Query: 1842 NCQPGYGGARCEYCAAGYYGIPE-DTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
+C+PG GG RC+ C G++ TD +G C PC+C +D C+ + G C
Sbjct: 813 SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSG--CTPCSCDPQGAVRD--DCEQMTGLC-S 867
Query: 1901 CVNNTAGAACNLC-------APGFYGDAIFSKNCTACICDEFGMADCDSTTGT--CVC 1949
C AG C C G DA C C EFG A C +G+ CVC
Sbjct: 868 CKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRC-EFG-ARCVEESGSAHCVC 923
Score = 56.0 bits (129), Expect = 2e-06
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQ---DDNPDGCTKCFC 1531
C CN HG+ CD T QC C+ V G CD C+ ++N + D GCT C C
Sbjct: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSC 849
Score = 50.0 bits (114), Expect = 2e-04
Identities = 46/161 (28%), Positives = 71/161 (44%), Gaps = 15/161 (9%)
Query: 2852 FDGRGYATMAG-RGYLTPQSNQVLLFFRTYAPNGLIYLVGE--GGYFFSLLMQDGRVYLQ 2908
F+GR + R Y T + + L FR P GL+ G G F +L + DGRV L+
Sbjct: 1377 FEGRSFLAFPTLRAYHTLR---LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLR 1433
Query: 2909 VSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDT 2968
G+ ++ + G+WH+L+ R + +L+VD E + D +LDT
Sbjct: 1434 FDTGSGP--AVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDT 1491
Query: 2969 MNF-GGNNKGILQVP------DRGFDGCMRQISINGVNLDL 3002
F GG + V G GC+R + +N L+L
Sbjct: 1492 DLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLEL 1532
Score = 47.6 bits (108), Expect = 8e-04
Identities = 19/48 (39%), Positives = 23/48 (47%)
Query: 1329 ITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTG 1376
I ++ SG PC CD G+ +C G C CKP V G C C G
Sbjct: 836 IVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG 883
Score = 47.2 bits (107), Expect = 0.001
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYND 3392
L + FR + QG ++ Y +A K+ FLA + D ++ F+ G V++S
Sbjct: 1396 LALEFRALEPQG-LLLYNGNARGKD---FLALALLDGRVQLRFDTGSGPAVLTSAVPVEP 1451
Query: 3393 IDWHTVTLTRNGGHGKLAVDSE--MVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
WH + L+R+ G L+VD E ++GE S + L+L + GG+ ++
Sbjct: 1452 GQWHRLELSRHWRRGTLSVDGETPVLGE-SPSGTDGLNLDTDLFVGGVPEDQAAVALERT 1510
Query: 3451 NFYQPFMGCLKGLLMNGQQV 3470
GC++ L +N Q++
Sbjct: 1511 FVGAGLRGCIRLLDVNNQRL 1530
Score = 44.0 bits (99), Expect = 0.010
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Query: 3329 EGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH 3388
E L + F G +++ + K F++ +RD +L + ++ G VI S
Sbjct: 1660 EKMALEVVFLARGPSGLLLYNGQKTDGKG--DFVSLALRDRRLEFRYDLGKGAAVIRSRE 1717
Query: 3389 TYNDIDWHTVTLTRNGGHGKLAVDS--EMVGETSVTCNTPLSLAPPYYYGG 3437
W V+L RNG G L V ++GE+ V +T L+L P Y GG
Sbjct: 1718 PVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVP-HTVLNLKEPLYVGG 1767
Score = 43.2 bits (97), Expect = 0.018
Identities = 46/176 (26%), Positives = 74/176 (42%), Gaps = 12/176 (6%)
Query: 3498 THSNYLKLL-ENFKVGDEVSISMEVRPRNTTGLLL---SVHGKKDYMVLELLDSEVVANV 3553
T YL + E+ K + +R T GL+L + DY+ L ++D + +
Sbjct: 1873 TFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSY 1932
Query: 3554 ENGNGP--FRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTH 3611
G+ P R+T ++ +L + G S P +GA T DT
Sbjct: 1933 NLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTG--SSP-LGA-TQLDTD 1988
Query: 3612 SALYIGG-HERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVCP 3666
AL++GG E P+ GF GC+R++VVG P+ + AV + + CP
Sbjct: 1989 GALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTK-PELRPCP 2043
Score = 40.7 bits (91), Expect = 0.097
Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 18/160 (11%)
Query: 3517 ISMEVRPRNTTGLLL---SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLC 3573
+++E R GLLL + GK D++ L LLD V + G+GP T + +
Sbjct: 1396 LALEFRALEPQGLLLYNGNARGK-DFLALALLDGRVQLRFDTGSGPAVLTSAVPVE---- 1450
Query: 3574 DGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTS-TD---THSALYIGG--HERPIHKVR 3627
G WH++ DG P +G S TD + L++GG ++ +
Sbjct: 1451 PGQWHRLELSRHWRRGTLSVDG--ETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALE 1508
Query: 3628 GVHSRRGFTGCVRNIVVGETPVK--VPNSAVGRGAHVGVC 3665
G GC+R + V ++ + A RG+ VG C
Sbjct: 1509 RTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGEC 1548
Score = 40.7 bits (91), Expect = 0.097
Identities = 43/166 (25%), Positives = 69/166 (41%), Gaps = 14/166 (8%)
Query: 2852 FDGRG---YATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVG---EGGYFFSLLMQDGRV 2905
FDGR Y QSN L RT A GL+ G E + +L + DG +
Sbjct: 1869 FDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHL 1928
Query: 2906 YLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEV-LKAESNSPSADIP 2964
L +LG+ +++ +T N +W ++ A R + SL V NE + S + +
Sbjct: 1929 QLSYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLD 1986
Query: 2965 SLDTMNFGG-----NNKGILQVPDRGFDGCMRQISINGVNLDLSEN 3005
+ + GG + + GF GC+R + + L L E+
Sbjct: 1987 TDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLED 2032
Score = 39.9 bits (89), Expect = 0.17
Identities = 40/153 (26%), Positives = 56/153 (36%), Gaps = 26/153 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H DPA C C+ G +C++C GF + ++ R C P
Sbjct: 793 CQCNPHGSYGGTCDPATGQ----CSCRPGVGGLRCDRCEPGFWNFRGIVTDG--RSGCTP 846
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C DP+ + + + G C +C+ G C +C R G
Sbjct: 847 CSC---------DPQGAVR------DDCEQMTGLC-SCKPGVAGPKCGQCPDG--RALGP 888
Query: 351 RWDELDVCQPCQC-DPHFSTG-NCEEESGRCEC 381
E D P C + G C EESG C
Sbjct: 889 AGCEADASAPATCAEMRCEFGARCVEESGSAHC 921
Score = 35.9 bits (79), Expect = 2.8
Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 25/127 (19%)
Query: 2669 FRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSI 2728
FR E G +LY GN +G D++ + + +G + D G PA ++
Sbjct: 1400 FRALEPQGLLLYNGNARG--------KDFLALALLDGRVQLRFDTGSG------PAVLTS 1445
Query: 2729 DKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLY 2788
V +W+++ + R RR LS+ D T + + G NLD + L+
Sbjct: 1446 AVPVEPGQWHRLELSRHWRRGTLSV----DGETPVLGESPSGTDG----LNLDTD---LF 1494
Query: 2789 VGGVPSD 2795
VGGVP D
Sbjct: 1495 VGGVPED 1501
Score = 34.3 bits (75), Expect = 8.4
Identities = 41/179 (22%), Positives = 73/179 (40%), Gaps = 16/179 (8%)
Query: 2842 SSQSGPQEYRFDGRGYATMAGRGYLT-----PQSNQVLLFFRTYAPNGLIYLVGEG---- 2892
S Q G + D G++ + RG T + + + F P+GL+ G+
Sbjct: 1628 SGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGK 1687
Query: 2893 GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTV-DNEV 2951
G F SL ++D R+ + LG + ++ + G W ++ R K +L V D
Sbjct: 1688 GDFVSLALRDRRLEFRYDLG--KGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPR 1745
Query: 2952 LKAESNSPSADIPSLDTMNFGG----NNKGILQVPDRGFDGCMRQISINGVNLDLSENL 3006
+ ES P + + + GG + GFDG ++ +S+ G L E++
Sbjct: 1746 VLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHV 1804
>AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein.
Length = 2026
Score = 95.5 bits (227), Expect = 3e-18
Identities = 73/257 (28%), Positives = 100/257 (38%), Gaps = 36/257 (14%)
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFST--GN--CEEESGRCECRPEFQPPDCSSCAY 395
C R G WDE PC CD + G+ C + E + C S
Sbjct: 663 CEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 722
Query: 396 GYFDYPN-CK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CE 452
Y C+ P L HC T C C+ N G C + C+
Sbjct: 723 LYVAAQGACRGPTFAPLPPVAPLHCAQTPYGC-CQDNITAAR------GVGLAGCPSACQ 775
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--------PTCKPCNCDTSGT 504
CN GS CD TG C+C+ G C++C+ G++N+ C PC+CD G
Sbjct: 776 CNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGA 835
Query: 505 EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
C+ ++G C CK G GP+C QC G + LG P C+ S +C A+
Sbjct: 836 VRDDCEQMTGLCSCKPGVAGPKCGQCPDG---RALG------PAGCEADASAPATC-AEM 885
Query: 565 KC----NCLTNFGGAQC 577
+C C+ G A C
Sbjct: 886 RCEFGARCVEESGSAHC 902
Score = 87.4 bits (207), Expect = 9e-16
Identities = 115/415 (27%), Positives = 154/415 (37%), Gaps = 74/415 (17%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCV-PCQC------ 1767
GV Y EL T E Q R C QC G +G CV P +C
Sbjct: 487 GVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQP 546
Query: 1768 ----NGHS--DQCDVNTGICLNCADNTIGDH--CEFCMSGYHGDATVGTPRDCLICACPM 1819
+GH+ +C ++ C + + CE C V + C+ C
Sbjct: 547 VCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEH 606
Query: 1820 PYPSN-------NFALSCDLSENGSLISCNCQPGYGGARCEY--CAAGYYGIPEDTDLHT 1870
P P + +C+L E L + G CE C +G G ED D
Sbjct: 607 PPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGP-CEQAECGSGGSGSGEDGDCEQ 665
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTAC 1930
+ C G I +D S +G C+ + + +C G G +S C
Sbjct: 666 ----ELCRQRGGIWDED-----SEDGPCVCDFSCQSVPGSPVC--GSDG-VTYSTEC--- 710
Query: 1931 ICDEFGMADCDSTTGTCV-----CR-------PGVIGEKCDR----CAPDHWGLNTGLG- 1973
E A C+S G V CR P V C + C D+ G+G
Sbjct: 711 ---ELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGL 767
Query: 1974 --C-TPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT------KDGCDH 2023
C + C C S CD GQC C GV G +CD+C GFWN+ + GC
Sbjct: 768 AGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTP 827
Query: 2024 CNCNTGYSVGFMC-NATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
C+C+ +V C TG C C PGV G KC +CP+ L P GC E D+ A
Sbjct: 828 CSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGP-AGC-EADASAPA 880
Score = 80.2 bits (189), Expect = 1e-13
Identities = 93/386 (24%), Positives = 141/386 (36%), Gaps = 56/386 (14%)
Query: 433 GKSCEI----CEDGYYSPECKNCECNTVGSVSY--VCDKLTGDCTCKSKYSGRTCNQCQA 486
G +CE+ C G + C+ G + +C+ TG C C S+ C +
Sbjct: 491 GSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGS 550
Query: 487 GYYNYPT-CK----PCN------------CDTSGTEPSICDDV--SGQCICKAGFGGPRC 527
+ YP+ C C C+T G V +GQC+C PRC
Sbjct: 551 DGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVC------PRC 604
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
+ G V G + C+ + + + A+C G +
Sbjct: 605 EHPPPG---PVCGSDGVTYGSACELREAACLQQTQIEEARA-GPCEQAECGSGGSGSGED 660
Query: 588 PDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAK-CDTCREQFYNYPA-CE--ECNCDP- 642
DC C G I ++G C C + C Y CE + C+
Sbjct: 661 GDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQ 720
Query: 643 RGVTASFAGC------GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ-CNC 695
RG+ + G +P C G C C+ + GC C C
Sbjct: 721 RGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYG--C--CQDNITAARGVGLAGCPSACQC 776
Query: 696 NLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ---TNDVFGCTECDCDIGG 752
N G+ G C+ +GQC C+ VG +CD+C GF+ + T+ GCT C CD G
Sbjct: 777 NPHGSYG--GTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQG 834
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQ 778
++ ++C++ TG C C V G +C Q
Sbjct: 835 AVRDDCEQMTGLCSCKPGVAGPKCGQ 860
Score = 77.0 bits (181), Expect = 1e-12
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 23/180 (12%)
Query: 548 CNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKY--------PDCLSCNCDVS 598
C C+P GS +C A G+C+C GG +CD+C PG++ + C C+CD
Sbjct: 774 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 833
Query: 599 GSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF-----AGC 652
G++ C+ GLC CK G KC C + PA E + A A C
Sbjct: 834 GAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARC 893
Query: 653 GSVPAGELC-----QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
C C + ++C Y N + C Q L ++ SLG C
Sbjct: 894 VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQ---GLQISIQSLGPC 950
Score = 73.7 bits (173), Expect = 1e-11
Identities = 36/97 (37%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 1426 GCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--------PDCY 1476
GC C CNP G G C+ +G+C+CR V G CD C PG + F C
Sbjct: 769 GCPSACQCNPHGSYGGT--CDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCT 826
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE 1513
C+C+ G D C+Q T C CK V G C C +
Sbjct: 827 PCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPD 863
Score = 68.9 bits (161), Expect = 3e-10
Identities = 45/148 (30%), Positives = 63/148 (42%), Gaps = 12/148 (8%)
Query: 1376 GYYGFPNCRPC--HCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNF-----DVQRGC 1427
G G P+ C H CD G C C V G CDRC+P +NF D + GC
Sbjct: 766 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 825
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTY 1487
C+C+P G V + CE +G C+C+ V G C C G P + + T
Sbjct: 826 TPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCA 883
Query: 1488 DVCDQNTAQCYCKTNVRGQACD--TCKE 1513
++ + A+C ++ C TC E
Sbjct: 884 EMRCEFGARCVEESGSAHCVCPMLTCPE 911
Score = 68.5 bits (160), Expect = 4e-10
Identities = 98/387 (25%), Positives = 137/387 (35%), Gaps = 51/387 (13%)
Query: 372 CEEESGRCECRPE---FQPPDCSSCAYGYFD--YPNCKPCTCNLN---GTEGEHCTPTDG 423
CE E+GRC C E P C S + Y + CT ++ + G T D
Sbjct: 527 CEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDA 586
Query: 424 LCPC-KYNYAGKS-CEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
+C AG+ C CE P C + + T GS + + T + C
Sbjct: 587 VCAFGAVCSAGQCVCPRCEHPPPGPVCGS-DGVTYGSACELREAACLQQTQIEEARAGPC 645
Query: 482 NQCQAGYYNYPTCKPCNCDTS--GTEPSICDDVS--GQCICKAGF----GGPRCDQCLSG 533
Q + G + + +C+ I D+ S G C+C G P C
Sbjct: 646 EQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVT 705
Query: 534 YYMQVLGRERQC-------VPCNCDPTGSTSTSCSADGKCNCL-TNFGGAQCDQCSPGYY 585
Y + ++ +C V G T +C T +G Q + +
Sbjct: 706 YSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGV 765
Query: 586 KYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNY--------PAC 635
C S C C+ GS G TCD G C C+ G +CD C F+N+ C
Sbjct: 766 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 825
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCE---Q 692
C+CDP+G C + LC CK V G C C + + P GCE
Sbjct: 826 TPCSCDPQGAVRD--DCEQMTG--LCSCKPGVAGPKCGQCP----DGRALGPAGCEADAS 877
Query: 693 CNCNLAGTLNSLGA-CNTKSG--QCVC 716
A GA C +SG CVC
Sbjct: 878 APATCAEMRCEFGARCVEESGSAHCVC 904
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/393 (23%), Positives = 127/393 (32%), Gaps = 54/393 (13%)
Query: 415 GEHCTPTDGLCPCKYNYAGKSCEIC-EDGY-YSPECKNCECNTVGSVSYVCDKLTGDC-T 471
G C G C C + +C DG+ Y EC +S G C T
Sbjct: 524 GALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVAS-AGPCET 582
Query: 472 CKSKYS--GRTCN--QCQAGYYNYPTCKPCNCDTSG-TEPSICDDVSGQCICKAGFGGPR 526
C G C+ QC +P P C + G T S C+ C+ + R
Sbjct: 583 CGDAVCAFGAVCSAGQCVCPRCEHPPPGPV-CGSDGVTYGSACELREAACLQQTQIEEAR 641
Query: 527 ---CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC----NCLTNFGGAQCDQ 579
C+Q G G + C C G S DG C +C + G C
Sbjct: 642 AGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGS 701
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLC--------------HCKSNFDGAKCDTC 625
Y + C+ G G C HC G D
Sbjct: 702 DGVTYSTECELKKARCE--SQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNI 759
Query: 626 RE-QFYNYPACEE-CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ C C C+P G S+ G G+ C C+ V G C+ C+P +WN +
Sbjct: 760 TAARGVGLAGCPSACQCNPHG---SYGGTCDPATGQ-CSCRPGVGGLRCDRCEPGFWNFR 815
Query: 684 EY---NPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG------FYR 734
GC C+C+ G + C +G C CK V +C QC DG
Sbjct: 816 GIVTDGRSGCTPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCE 873
Query: 735 LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
+ C E C+ G C + +G HC
Sbjct: 874 ADASAPATCAEMRCEFGA----RCVEESGSAHC 902
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST-GNCEEESGRCEC 381
G+C +C+ G+ C++C P ++ G D C PC CDP + +CE+ +G C C
Sbjct: 791 GQC-SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSC 849
Query: 382 RPEFQPPDCSSCAYGYFDYP-NCK-----PCTC-NLNGTEGEHCTPTDG----LCPCKYN 430
+P P C C G P C+ P TC + G C G +CP
Sbjct: 850 KPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTC 909
Query: 431 YAGKSCEIC-EDGY-YSPECK 449
+ ++C DG Y EC+
Sbjct: 910 PEANATKVCGSDGVTYGNECQ 930
Score = 62.1 bits (144), Expect = 4e-08
Identities = 53/189 (28%), Positives = 71/189 (37%), Gaps = 25/189 (13%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--------PNCRPCHC-PS 1390
C C+ GS C+ GQC C+P V G C C G++ F C PC C P
Sbjct: 774 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 833
Query: 1391 TAICDD----NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
A+ DD G+C C V G C +C P GC+ P +++CE
Sbjct: 834 GAVRDDCEQMTGLCSCKPGVAGPKCGQC-PDGRALG-PAGCEADASAPATCA--EMRCEF 889
Query: 1447 DSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTY-DVCDQNTAQCYCKTNVR 1504
+C V HCV P+ C G TY + C T C +
Sbjct: 890 -GARC-----VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQIS 943
Query: 1505 GQACDTCKE 1513
Q+ C+E
Sbjct: 944 IQSLGPCQE 952
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/178 (29%), Positives = 73/178 (41%), Gaps = 28/178 (15%)
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
L+CA G C+ ++ G G P C C P ++ +CD + C
Sbjct: 745 LHCAQTPYGC-CQDNITAARGVGLAGCPS---ACQCN---PHGSYGGTCDPATG----QC 793
Query: 1842 NCQPGYGGARCEYCAAGYYGIPE-DTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
+C+PG GG RC+ C G++ TD +G C PC+C +D C+ + G C
Sbjct: 794 SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSG--CTPCSCDPQGAVRD--DCEQMTGLC-S 848
Query: 1901 CVNNTAGAACNLC-------APGFYGDAIFSKNCTACICDEFGMADCDSTTGT--CVC 1949
C AG C C G DA C C EFG A C +G+ CVC
Sbjct: 849 CKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRC-EFG-ARCVEESGSAHCVC 904
Score = 56.0 bits (129), Expect = 2e-06
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQ---DDNPDGCTKCFC 1531
C CN HG+ CD T QC C+ V G CD C+ ++N + D GCT C C
Sbjct: 774 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSC 830
Score = 50.0 bits (114), Expect = 2e-04
Identities = 46/161 (28%), Positives = 71/161 (44%), Gaps = 15/161 (9%)
Query: 2852 FDGRGYATMAG-RGYLTPQSNQVLLFFRTYAPNGLIYLVGE--GGYFFSLLMQDGRVYLQ 2908
F+GR + R Y T + + L FR P GL+ G G F +L + DGRV L+
Sbjct: 1358 FEGRSFLAFPTLRAYHTLR---LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLR 1414
Query: 2909 VSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDT 2968
G+ ++ + G+WH+L+ R + +L+VD E + D +LDT
Sbjct: 1415 FDTGSGP--AVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDT 1472
Query: 2969 MNF-GGNNKGILQVP------DRGFDGCMRQISINGVNLDL 3002
F GG + V G GC+R + +N L+L
Sbjct: 1473 DLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLEL 1513
Score = 47.6 bits (108), Expect = 8e-04
Identities = 19/48 (39%), Positives = 23/48 (47%)
Query: 1329 ITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTG 1376
I ++ SG PC CD G+ +C G C CKP V G C C G
Sbjct: 817 IVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG 864
Score = 47.2 bits (107), Expect = 0.001
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYND 3392
L + FR + QG ++ Y +A K+ FLA + D ++ F+ G V++S
Sbjct: 1377 LALEFRALEPQG-LLLYNGNARGKD---FLALALLDGRVQLRFDTGSGPAVLTSAVPVEP 1432
Query: 3393 IDWHTVTLTRNGGHGKLAVDSE--MVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
WH + L+R+ G L+VD E ++GE S + L+L + GG+ ++
Sbjct: 1433 GQWHRLELSRHWRRGTLSVDGETPVLGE-SPSGTDGLNLDTDLFVGGVPEDQAAVALERT 1491
Query: 3451 NFYQPFMGCLKGLLMNGQQV 3470
GC++ L +N Q++
Sbjct: 1492 FVGAGLRGCIRLLDVNNQRL 1511
Score = 44.0 bits (99), Expect = 0.010
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Query: 3329 EGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH 3388
E L + F G +++ + K F++ +RD +L + ++ G VI S
Sbjct: 1641 EKMALEVVFLARGPSGLLLYNGQKTDGKG--DFVSLALRDRRLEFRYDLGKGAAVIRSRE 1698
Query: 3389 TYNDIDWHTVTLTRNGGHGKLAVDS--EMVGETSVTCNTPLSLAPPYYYGG 3437
W V+L RNG G L V ++GE+ V +T L+L P Y GG
Sbjct: 1699 PVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVP-HTVLNLKEPLYVGG 1748
Score = 43.2 bits (97), Expect = 0.018
Identities = 46/176 (26%), Positives = 74/176 (42%), Gaps = 12/176 (6%)
Query: 3498 THSNYLKLL-ENFKVGDEVSISMEVRPRNTTGLLL---SVHGKKDYMVLELLDSEVVANV 3553
T YL + E+ K + +R T GL+L + DY+ L ++D + +
Sbjct: 1854 TFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSY 1913
Query: 3554 ENGNGP--FRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTH 3611
G+ P R+T ++ +L + G S P +GA T DT
Sbjct: 1914 NLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTG--SSP-LGA-TQLDTD 1969
Query: 3612 SALYIGG-HERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVCP 3666
AL++GG E P+ GF GC+R++VVG P+ + AV + + CP
Sbjct: 1970 GALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTK-PELRPCP 2024
Score = 40.7 bits (91), Expect = 0.097
Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 18/160 (11%)
Query: 3517 ISMEVRPRNTTGLLL---SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLC 3573
+++E R GLLL + GK D++ L LLD V + G+GP T + +
Sbjct: 1377 LALEFRALEPQGLLLYNGNARGK-DFLALALLDGRVQLRFDTGSGPAVLTSAVPVE---- 1431
Query: 3574 DGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTS-TD---THSALYIGG--HERPIHKVR 3627
G WH++ DG P +G S TD + L++GG ++ +
Sbjct: 1432 PGQWHRLELSRHWRRGTLSVDG--ETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALE 1489
Query: 3628 GVHSRRGFTGCVRNIVVGETPVK--VPNSAVGRGAHVGVC 3665
G GC+R + V ++ + A RG+ VG C
Sbjct: 1490 RTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGEC 1529
Score = 40.7 bits (91), Expect = 0.097
Identities = 43/166 (25%), Positives = 69/166 (41%), Gaps = 14/166 (8%)
Query: 2852 FDGRG---YATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVG---EGGYFFSLLMQDGRV 2905
FDGR Y QSN L RT A GL+ G E + +L + DG +
Sbjct: 1850 FDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHL 1909
Query: 2906 YLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEV-LKAESNSPSADIP 2964
L +LG+ +++ +T N +W ++ A R + SL V NE + S + +
Sbjct: 1910 QLSYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLD 1967
Query: 2965 SLDTMNFGG-----NNKGILQVPDRGFDGCMRQISINGVNLDLSEN 3005
+ + GG + + GF GC+R + + L L E+
Sbjct: 1968 TDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLED 2013
Score = 39.9 bits (89), Expect = 0.17
Identities = 40/153 (26%), Positives = 56/153 (36%), Gaps = 26/153 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H DPA C C+ G +C++C GF + ++ R C P
Sbjct: 774 CQCNPHGSYGGTCDPATGQ----CSCRPGVGGLRCDRCEPGFWNFRGIVTDG--RSGCTP 827
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C DP+ + + + G C +C+ G C +C R G
Sbjct: 828 CSC---------DPQGAVR------DDCEQMTGLC-SCKPGVAGPKCGQCPDG--RALGP 869
Query: 351 RWDELDVCQPCQC-DPHFSTG-NCEEESGRCEC 381
E D P C + G C EESG C
Sbjct: 870 AGCEADASAPATCAEMRCEFGARCVEESGSAHC 902
Score = 35.9 bits (79), Expect = 2.8
Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 25/127 (19%)
Query: 2669 FRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSI 2728
FR E G +LY GN +G D++ + + +G + D G PA ++
Sbjct: 1381 FRALEPQGLLLYNGNARG--------KDFLALALLDGRVQLRFDTGSG------PAVLTS 1426
Query: 2729 DKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLY 2788
V +W+++ + R RR LS+ D T + + G NLD + L+
Sbjct: 1427 AVPVEPGQWHRLELSRHWRRGTLSV----DGETPVLGESPSGTDG----LNLDTD---LF 1475
Query: 2789 VGGVPSD 2795
VGGVP D
Sbjct: 1476 VGGVPED 1482
Score = 34.3 bits (75), Expect = 8.4
Identities = 41/179 (22%), Positives = 73/179 (40%), Gaps = 16/179 (8%)
Query: 2842 SSQSGPQEYRFDGRGYATMAGRGYLT-----PQSNQVLLFFRTYAPNGLIYLVGEG---- 2892
S Q G + D G++ + RG T + + + F P+GL+ G+
Sbjct: 1609 SGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGK 1668
Query: 2893 GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTV-DNEV 2951
G F SL ++D R+ + LG + ++ + G W ++ R K +L V D
Sbjct: 1669 GDFVSLALRDRRLEFRYDLG--KGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPR 1726
Query: 2952 LKAESNSPSADIPSLDTMNFGG----NNKGILQVPDRGFDGCMRQISINGVNLDLSENL 3006
+ ES P + + + GG + GFDG ++ +S+ G L E++
Sbjct: 1727 VLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHV 1785
>AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 95.5 bits (227), Expect = 3e-18
Identities = 73/257 (28%), Positives = 100/257 (38%), Gaps = 36/257 (14%)
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFST--GN--CEEESGRCECRPEFQPPDCSSCAY 395
C R G WDE PC CD + G+ C + E + C S
Sbjct: 682 CEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 741
Query: 396 GYFDYPN-CK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CE 452
Y C+ P L HC T C C+ N G C + C+
Sbjct: 742 LYVAAQGACRGPTFAPLPPVAPLHCAQTPYGC-CQDNITAAR------GVGLAGCPSACQ 794
Query: 453 CNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY--------PTCKPCNCDTSGT 504
CN GS CD TG C+C+ G C++C+ G++N+ C PC+CD G
Sbjct: 795 CNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGA 854
Query: 505 EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
C+ ++G C CK G GP+C QC G + LG P C+ S +C A+
Sbjct: 855 VRDDCEQMTGLCSCKPGVAGPKCGQCPDG---RALG------PAGCEADASAPATC-AEM 904
Query: 565 KC----NCLTNFGGAQC 577
+C C+ G A C
Sbjct: 905 RCEFGARCVEESGSAHC 921
Score = 87.4 bits (207), Expect = 9e-16
Identities = 115/415 (27%), Positives = 154/415 (37%), Gaps = 74/415 (17%)
Query: 1716 GVDYYMGDELVVRRATSVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCV-PCQC------ 1767
GV Y EL T E Q R C QC G +G CV P +C
Sbjct: 506 GVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQP 565
Query: 1768 ----NGHS--DQCDVNTGICLNCADNTIGDH--CEFCMSGYHGDATVGTPRDCLICACPM 1819
+GH+ +C ++ C + + CE C V + C+ C
Sbjct: 566 VCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEH 625
Query: 1820 PYPSN-------NFALSCDLSENGSLISCNCQPGYGGARCEY--CAAGYYGIPEDTDLHT 1870
P P + +C+L E L + G CE C +G G ED D
Sbjct: 626 PPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGP-CEQAECGSGGSGSGEDGDCEQ 684
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTAC 1930
+ C G I +D S +G C+ + + +C G G +S C
Sbjct: 685 ----ELCRQRGGIWDED-----SEDGPCVCDFSCQSVPGSPVC--GSDG-VTYSTEC--- 729
Query: 1931 ICDEFGMADCDSTTGTCV-----CR-------PGVIGEKCDR----CAPDHWGLNTGLG- 1973
E A C+S G V CR P V C + C D+ G+G
Sbjct: 730 ---ELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGL 786
Query: 1974 --C-TPCNCGI-ASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT------KDGCDH 2023
C + C C S CD GQC C GV G +CD+C GFWN+ + GC
Sbjct: 787 AGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTP 846
Query: 2024 CNCNTGYSVGFMC-NATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
C+C+ +V C TG C C PGV G KC +CP+ L P GC E D+ A
Sbjct: 847 CSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGP-AGC-EADASAPA 899
Score = 80.2 bits (189), Expect = 1e-13
Identities = 93/386 (24%), Positives = 141/386 (36%), Gaps = 56/386 (14%)
Query: 433 GKSCEI----CEDGYYSPECKNCECNTVGSVSY--VCDKLTGDCTCKSKYSGRTCNQCQA 486
G +CE+ C G + C+ G + +C+ TG C C S+ C +
Sbjct: 510 GSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGS 569
Query: 487 GYYNYPT-CK----PCN------------CDTSGTEPSICDDV--SGQCICKAGFGGPRC 527
+ YP+ C C C+T G V +GQC+C PRC
Sbjct: 570 DGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVC------PRC 623
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKY 587
+ G V G + C+ + + + A+C G +
Sbjct: 624 EHPPPG---PVCGSDGVTYGSACELREAACLQQTQIEEARA-GPCEQAECGSGGSGSGED 679
Query: 588 PDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAK-CDTCREQFYNYPA-CE--ECNCDP- 642
DC C G I ++G C C + C Y CE + C+
Sbjct: 680 GDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQ 739
Query: 643 RGVTASFAGC------GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ-CNC 695
RG+ + G +P C G C C+ + GC C C
Sbjct: 740 RGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYG--C--CQDNITAARGVGLAGCPSACQC 795
Query: 696 NLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ---TNDVFGCTECDCDIGG 752
N G+ G C+ +GQC C+ VG +CD+C GF+ + T+ GCT C CD G
Sbjct: 796 NPHGSYG--GTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQG 853
Query: 753 SIDNNCDKTTGQCHCHSRVEGRRCDQ 778
++ ++C++ TG C C V G +C Q
Sbjct: 854 AVRDDCEQMTGLCSCKPGVAGPKCGQ 879
Score = 77.0 bits (181), Expect = 1e-12
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 23/180 (12%)
Query: 548 CNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKY--------PDCLSCNCDVS 598
C C+P GS +C A G+C+C GG +CD+C PG++ + C C+CD
Sbjct: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 852
Query: 599 GSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF-----AGC 652
G++ C+ GLC CK G KC C + PA E + A A C
Sbjct: 853 GAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARC 912
Query: 653 GSVPAGELC-----QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
C C + ++C Y N + C Q L ++ SLG C
Sbjct: 913 VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQ---GLQISIQSLGPC 969
Score = 73.7 bits (173), Expect = 1e-11
Identities = 36/97 (37%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 1426 GCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF--------PDCY 1476
GC C CNP G G C+ +G+C+CR V G CD C PG + F C
Sbjct: 788 GCPSACQCNPHGSYGGT--CDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCT 845
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKE 1513
C+C+ G D C+Q T C CK V G C C +
Sbjct: 846 PCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPD 882
Score = 68.9 bits (161), Expect = 3e-10
Identities = 45/148 (30%), Positives = 63/148 (42%), Gaps = 12/148 (8%)
Query: 1376 GYYGFPNCRPC--HCPSTAICDD-NGMCICPKNVEGENCDRCKPYTFNF-----DVQRGC 1427
G G P+ C H CD G C C V G CDRC+P +NF D + GC
Sbjct: 785 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 844
Query: 1428 DDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTY 1487
C+C+P G V + CE +G C+C+ V G C C G P + + T
Sbjct: 845 TPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCA 902
Query: 1488 DVCDQNTAQCYCKTNVRGQACD--TCKE 1513
++ + A+C ++ C TC E
Sbjct: 903 EMRCEFGARCVEESGSAHCVCPMLTCPE 930
Score = 68.5 bits (160), Expect = 4e-10
Identities = 98/387 (25%), Positives = 137/387 (35%), Gaps = 51/387 (13%)
Query: 372 CEEESGRCECRPE---FQPPDCSSCAYGYFD--YPNCKPCTCNLN---GTEGEHCTPTDG 423
CE E+GRC C E P C S + Y + CT ++ + G T D
Sbjct: 546 CEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDA 605
Query: 424 LCPC-KYNYAGKS-CEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
+C AG+ C CE P C + + T GS + + T + C
Sbjct: 606 VCAFGAVCSAGQCVCPRCEHPPPGPVCGS-DGVTYGSACELREAACLQQTQIEEARAGPC 664
Query: 482 NQCQAGYYNYPTCKPCNCDTS--GTEPSICDDVS--GQCICKAGF----GGPRCDQCLSG 533
Q + G + + +C+ I D+ S G C+C G P C
Sbjct: 665 EQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVT 724
Query: 534 YYMQVLGRERQC-------VPCNCDPTGSTSTSCSADGKCNCL-TNFGGAQCDQCSPGYY 585
Y + ++ +C V G T +C T +G Q + +
Sbjct: 725 YSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGV 784
Query: 586 KYPDCLS-CNCDVSGSIGSTCDD-NGLCHCKSNFDGAKCDTCREQFYNY--------PAC 635
C S C C+ GS G TCD G C C+ G +CD C F+N+ C
Sbjct: 785 GLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGC 844
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCE---Q 692
C+CDP+G C + LC CK V G C C + + P GCE
Sbjct: 845 TPCSCDPQGAVRD--DCEQMTG--LCSCKPGVAGPKCGQCP----DGRALGPAGCEADAS 896
Query: 693 CNCNLAGTLNSLGA-CNTKSG--QCVC 716
A GA C +SG CVC
Sbjct: 897 APATCAEMRCEFGARCVEESGSAHCVC 923
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/393 (23%), Positives = 127/393 (32%), Gaps = 54/393 (13%)
Query: 415 GEHCTPTDGLCPCKYNYAGKSCEIC-EDGY-YSPECKNCECNTVGSVSYVCDKLTGDC-T 471
G C G C C + +C DG+ Y EC +S G C T
Sbjct: 543 GALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVAS-AGPCET 601
Query: 472 CKSKYS--GRTCN--QCQAGYYNYPTCKPCNCDTSG-TEPSICDDVSGQCICKAGFGGPR 526
C G C+ QC +P P C + G T S C+ C+ + R
Sbjct: 602 CGDAVCAFGAVCSAGQCVCPRCEHPPPGPV-CGSDGVTYGSACELREAACLQQTQIEEAR 660
Query: 527 ---CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC----NCLTNFGGAQCDQ 579
C+Q G G + C C G S DG C +C + G C
Sbjct: 661 AGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGS 720
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLC--------------HCKSNFDGAKCDTC 625
Y + C+ G G C HC G D
Sbjct: 721 DGVTYSTECELKKARCE--SQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNI 778
Query: 626 RE-QFYNYPACEE-CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ C C C+P G S+ G G+ C C+ V G C+ C+P +WN +
Sbjct: 779 TAARGVGLAGCPSACQCNPHG---SYGGTCDPATGQ-CSCRPGVGGLRCDRCEPGFWNFR 834
Query: 684 EY---NPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG------FYR 734
GC C+C+ G + C +G C CK V +C QC DG
Sbjct: 835 GIVTDGRSGCTPCSCDPQGAVRD--DCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCE 892
Query: 735 LQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
+ C E C+ G C + +G HC
Sbjct: 893 ADASAPATCAEMRCEFGA----RCVEESGSAHC 921
Score = 64.5 bits (150), Expect = 7e-09
Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST-GNCEEESGRCEC 381
G+C +C+ G+ C++C P ++ G D C PC CDP + +CE+ +G C C
Sbjct: 810 GQC-SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSC 868
Query: 382 RPEFQPPDCSSCAYGYFDYP-NCK-----PCTC-NLNGTEGEHCTPTDG----LCPCKYN 430
+P P C C G P C+ P TC + G C G +CP
Sbjct: 869 KPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTC 928
Query: 431 YAGKSCEIC-EDGY-YSPECK 449
+ ++C DG Y EC+
Sbjct: 929 PEANATKVCGSDGVTYGNECQ 949
Score = 62.1 bits (144), Expect = 4e-08
Identities = 53/189 (28%), Positives = 71/189 (37%), Gaps = 25/189 (13%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGF--------PNCRPCHC-PS 1390
C C+ GS C+ GQC C+P V G C C G++ F C PC C P
Sbjct: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 852
Query: 1391 TAICDD----NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
A+ DD G+C C V G C +C P GC+ P +++CE
Sbjct: 853 GAVRDDCEQMTGLCSCKPGVAGPKCGQC-PDGRALG-PAGCEADASAPATCA--EMRCEF 908
Query: 1447 DSGKCACRENVRGRVCDHCVPGHYAFPDCYQC-TCNRHGTTY-DVCDQNTAQCYCKTNVR 1504
+C V HCV P+ C G TY + C T C +
Sbjct: 909 -GARC-----VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQIS 962
Query: 1505 GQACDTCKE 1513
Q+ C+E
Sbjct: 963 IQSLGPCQE 971
Score = 61.3 bits (142), Expect = 6e-08
Identities = 53/178 (29%), Positives = 73/178 (41%), Gaps = 28/178 (15%)
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
L+CA G C+ ++ G G P C C P ++ +CD + C
Sbjct: 764 LHCAQTPYGC-CQDNITAARGVGLAGCPS---ACQCN---PHGSYGGTCDPATG----QC 812
Query: 1842 NCQPGYGGARCEYCAAGYYGIPE-DTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
+C+PG GG RC+ C G++ TD +G C PC+C +D C+ + G C
Sbjct: 813 SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSG--CTPCSCDPQGAVRD--DCEQMTGLC-S 867
Query: 1901 CVNNTAGAACNLC-------APGFYGDAIFSKNCTACICDEFGMADCDSTTGT--CVC 1949
C AG C C G DA C C EFG A C +G+ CVC
Sbjct: 868 CKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRC-EFG-ARCVEESGSAHCVC 923
Score = 56.0 bits (129), Expect = 2e-06
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQ---DDNPDGCTKCFC 1531
C CN HG+ CD T QC C+ V G CD C+ ++N + D GCT C C
Sbjct: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSC 849
Score = 50.0 bits (114), Expect = 2e-04
Identities = 46/161 (28%), Positives = 71/161 (44%), Gaps = 15/161 (9%)
Query: 2852 FDGRGYATMAG-RGYLTPQSNQVLLFFRTYAPNGLIYLVGE--GGYFFSLLMQDGRVYLQ 2908
F+GR + R Y T + + L FR P GL+ G G F +L + DGRV L+
Sbjct: 1377 FEGRSFLAFPTLRAYHTLR---LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLR 1433
Query: 2909 VSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDT 2968
G+ ++ + G+WH+L+ R + +L+VD E + D +LDT
Sbjct: 1434 FDTGSGP--AVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDT 1491
Query: 2969 MNF-GGNNKGILQVP------DRGFDGCMRQISINGVNLDL 3002
F GG + V G GC+R + +N L+L
Sbjct: 1492 DLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLEL 1532
Score = 47.6 bits (108), Expect = 8e-04
Identities = 19/48 (39%), Positives = 23/48 (47%)
Query: 1329 ITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTG 1376
I ++ SG PC CD G+ +C G C CKP V G C C G
Sbjct: 836 IVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG 883
Score = 47.2 bits (107), Expect = 0.001
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYND 3392
L + FR + QG ++ Y +A K+ FLA + D ++ F+ G V++S
Sbjct: 1396 LALEFRALEPQG-LLLYNGNARGKD---FLALALLDGRVQLRFDTGSGPAVLTSAVPVEP 1451
Query: 3393 IDWHTVTLTRNGGHGKLAVDSE--MVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFD 3450
WH + L+R+ G L+VD E ++GE S + L+L + GG+ ++
Sbjct: 1452 GQWHRLELSRHWRRGTLSVDGETPVLGE-SPSGTDGLNLDTDLFVGGVPEDQAAVALERT 1510
Query: 3451 NFYQPFMGCLKGLLMNGQQV 3470
GC++ L +N Q++
Sbjct: 1511 FVGAGLRGCIRLLDVNNQRL 1530
Score = 44.0 bits (99), Expect = 0.010
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Query: 3329 EGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTH 3388
E L + F G +++ + K F++ +RD +L + ++ G VI S
Sbjct: 1660 EKMALEVVFLARGPSGLLLYNGQKTDGKG--DFVSLALRDRRLEFRYDLGKGAAVIRSRE 1717
Query: 3389 TYNDIDWHTVTLTRNGGHGKLAVDS--EMVGETSVTCNTPLSLAPPYYYGG 3437
W V+L RNG G L V ++GE+ V +T L+L P Y GG
Sbjct: 1718 PVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVP-HTVLNLKEPLYVGG 1767
Score = 43.2 bits (97), Expect = 0.018
Identities = 46/176 (26%), Positives = 74/176 (42%), Gaps = 12/176 (6%)
Query: 3498 THSNYLKLL-ENFKVGDEVSISMEVRPRNTTGLLL---SVHGKKDYMVLELLDSEVVANV 3553
T YL + E+ K + +R T GL+L + DY+ L ++D + +
Sbjct: 1873 TFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSY 1932
Query: 3554 ENGNGP--FRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTH 3611
G+ P R+T ++ +L + G S P +GA T DT
Sbjct: 1933 NLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTG--SSP-LGA-TQLDTD 1988
Query: 3612 SALYIGG-HERPIHKVRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHVGVCP 3666
AL++GG E P+ GF GC+R++VVG P+ + AV + + CP
Sbjct: 1989 GALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTK-PELRPCP 2043
Score = 40.7 bits (91), Expect = 0.097
Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 18/160 (11%)
Query: 3517 ISMEVRPRNTTGLLL---SVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYLC 3573
+++E R GLLL + GK D++ L LLD V + G+GP T + +
Sbjct: 1396 LALEFRALEPQGLLLYNGNARGK-DFLALALLDGRVQLRFDTGSGPAVLTSAVPVE---- 1450
Query: 3574 DGNWHKIHXXXXXXXXXXXXDGHFSKPGIGAYTS-TD---THSALYIGG--HERPIHKVR 3627
G WH++ DG P +G S TD + L++GG ++ +
Sbjct: 1451 PGQWHRLELSRHWRRGTLSVDG--ETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALE 1508
Query: 3628 GVHSRRGFTGCVRNIVVGETPVK--VPNSAVGRGAHVGVC 3665
G GC+R + V ++ + A RG+ VG C
Sbjct: 1509 RTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGEC 1548
Score = 40.7 bits (91), Expect = 0.097
Identities = 43/166 (25%), Positives = 69/166 (41%), Gaps = 14/166 (8%)
Query: 2852 FDGRG---YATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLVG---EGGYFFSLLMQDGRV 2905
FDGR Y QSN L RT A GL+ G E + +L + DG +
Sbjct: 1869 FDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHL 1928
Query: 2906 YLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEV-LKAESNSPSADIP 2964
L +LG+ +++ +T N +W ++ A R + SL V NE + S + +
Sbjct: 1929 QLSYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLD 1986
Query: 2965 SLDTMNFGG-----NNKGILQVPDRGFDGCMRQISINGVNLDLSEN 3005
+ + GG + + GF GC+R + + L L E+
Sbjct: 1987 TDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLED 2032
Score = 39.9 bits (89), Expect = 0.17
Identities = 40/153 (26%), Positives = 56/153 (36%), Gaps = 26/153 (16%)
Query: 231 CMCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP 290
C CN H DPA C C+ G +C++C GF + ++ R C P
Sbjct: 793 CQCNPHGSYGGTCDPATGQ----CSCRPGVGGLRCDRCEPGFWNFRGIVTDG--RSGCTP 846
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C+C DP+ + + + G C +C+ G C +C R G
Sbjct: 847 CSC---------DPQGAVR------DDCEQMTGLC-SCKPGVAGPKCGQCPDG--RALGP 888
Query: 351 RWDELDVCQPCQC-DPHFSTG-NCEEESGRCEC 381
E D P C + G C EESG C
Sbjct: 889 AGCEADASAPATCAEMRCEFGARCVEESGSAHC 921
Score = 35.9 bits (79), Expect = 2.8
Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 25/127 (19%)
Query: 2669 FRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDPARVSI 2728
FR E G +LY GN +G D++ + + +G + D G PA ++
Sbjct: 1400 FRALEPQGLLLYNGNARG--------KDFLALALLDGRVQLRFDTGSG------PAVLTS 1445
Query: 2729 DKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKEKSKLY 2788
V +W+++ + R RR LS+ D T + + G NLD + L+
Sbjct: 1446 AVPVEPGQWHRLELSRHWRRGTLSV----DGETPVLGESPSGTDG----LNLDTD---LF 1494
Query: 2789 VGGVPSD 2795
VGGVP D
Sbjct: 1495 VGGVPED 1501
Score = 34.3 bits (75), Expect = 8.4
Identities = 41/179 (22%), Positives = 73/179 (40%), Gaps = 16/179 (8%)
Query: 2842 SSQSGPQEYRFDGRGYATMAGRGYLT-----PQSNQVLLFFRTYAPNGLIYLVGEG---- 2892
S Q G + D G++ + RG T + + + F P+GL+ G+
Sbjct: 1628 SGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGK 1687
Query: 2893 GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTV-DNEV 2951
G F SL ++D R+ + LG + ++ + G W ++ R K +L V D
Sbjct: 1688 GDFVSLALRDRRLEFRYDLG--KGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPR 1745
Query: 2952 LKAESNSPSADIPSLDTMNFGG----NNKGILQVPDRGFDGCMRQISINGVNLDLSENL 3006
+ ES P + + + GG + GFDG ++ +S+ G L E++
Sbjct: 1746 VLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHV 1804
>AK098809-1|BAC05419.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ25943 fis, clone JTH10559. ).
Length = 320
Score = 95.1 bits (226), Expect = 4e-18
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 18/174 (10%)
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDC-SSCAYGYFDYPNCKPCTCNLNGTEGEH 417
Q C+C + G C+ +G+C C P + C C G F + C C
Sbjct: 75 QECRCH---NGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC----APDAR 127
Query: 418 CTPTDGLCPCKYNYAGKSC--EICEDGYYSPECK-NCECNTVGSVSYVCDKLTGDCTCKS 474
C P +G C C++ + G C +C DG+Y C+ C C+ S+S C + G+C+C
Sbjct: 128 CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS--CHPMNGECSCLP 185
Query: 475 KYSGRTCNQCQAGYYNYPTCKP-CNCDTSGTEPSICDDVSGQCICKAGFGGPRC 527
++G CN+ + P C+ C C G +C SG C C G+ GP C
Sbjct: 186 GWAGLHCNESCPQDTHGPGCQEHCLCLHGG----VCQATSGLCQCAPGYTGPHC 235
Score = 94.7 bits (225), Expect = 6e-18
Identities = 74/225 (32%), Positives = 94/225 (41%), Gaps = 39/225 (17%)
Query: 1840 SCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
SC+C PG+ G C C G++G P NCS + G CD G C
Sbjct: 48 SCSCPPGWMGTICSLPCPEGFHG--------------P-NCSQECRCHNGGLCDRFTGQC 92
Query: 1899 LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
+C G C C G +G ++C A CD A C G C+C G G++
Sbjct: 93 -RCAPGYTGDRCREECPVGRFG-----QDC-AETCDCAPDARCFPANGACLCEHGFTGDR 145
Query: 1958 C-DRCAPDHWGLNTGLGC-TPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN 2015
C DR PD + GL C PC C S C NG+C C G G C++ +
Sbjct: 146 CTDRLCPDGF---YGLSCQAPCTCD-REHSLSCHPMNGECSCLPGWAGLHCNESCP--QD 199
Query: 2016 YTKDGC-DHCNCNTGYSVGFMCNAT-GQCECLPGVIGEKC-DRCP 2057
GC +HC C G +C AT G C+C PG G C CP
Sbjct: 200 THGPGCQEHCLC----LHGGVCQATSGLCQCAPGYTGPHCASLCP 240
Score = 89.4 bits (212), Expect = 2e-16
Identities = 83/286 (29%), Positives = 110/286 (38%), Gaps = 57/286 (19%)
Query: 401 PNC-KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSV 459
P C KPC+C N + C P G G S G++ P C+ V
Sbjct: 4 PQCDKPCSCGNNSS----CDPKSG---------GTS------GFFCPSTHPCQNGGVFQT 44
Query: 460 SYVCDKLTGDCTCKSKYSGRTCN-QCQAGYYNYPTC-KPCNCDTSGTEPSICDDVSGQCI 517
G C+C + G C+ C G++ P C + C C G +CD +GQC
Sbjct: 45 PQ------GSCSCPPGWMGTICSLPCPEGFHG-PNCSQECRCHNGG----LCDRFTGQCR 93
Query: 518 CKAGFGGPRC-DQCLSGYYMQVLGRERQCVP-CNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C G+ G RC ++C G + Q C P C P A+G C C F G
Sbjct: 94 CAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFP---------ANGACLCEHGFTGD 144
Query: 576 QCDQ--CSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYP 633
+C C G+Y C CD S+ S NG C C + G C+ Q + P
Sbjct: 145 RCTDRLCPDGFYGLSCQAPCTCDREHSL-SCHPMNGECSCLPGWAGLHCNESCPQDTHGP 203
Query: 634 ACEE-CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKP 677
C+E C C GV + +G LCQC G C C P
Sbjct: 204 GCQEHCLCLHGGVCQATSG--------LCQCAPGYTGPHCASLCPP 241
Score = 83.0 bits (196), Expect = 2e-14
Identities = 77/261 (29%), Positives = 97/261 (37%), Gaps = 52/261 (19%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEF---CMSGYHGDATVGT---PRDCLICAC 1817
PC C G++ CD +G T G C C +G G+ P + C
Sbjct: 9 PCSC-GNNSSCDPKSG-------GTSGFFCPSTHPCQNGGVFQTPQGSCSCPPGWMGTIC 60
Query: 1818 PMPYPSNNFALSCDLS---ENGSLIS-----CNCQPGYGGARC-EYCAAGYYGIPEDTDL 1868
+P P +C NG L C C PGY G RC E C G +G
Sbjct: 61 SLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFG------- 113
Query: 1869 HTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDAIFSKN 1926
D + C+C+ + C NG CL C + G C LC GFYG +
Sbjct: 114 --QDCAETCDCAPDAR------CFPANGACL-CEHGFTGDRCTDRLCPDGFYG-----LS 159
Query: 1927 CTA-CICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASES 1985
C A C CD C G C C PG G C+ P G GC +C +
Sbjct: 160 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQD---THGPGCQE-HC-LCLHG 214
Query: 1986 TQCDDDNGQCRCAKGVTGKQC 2006
C +G C+CA G TG C
Sbjct: 215 GVCQATSGLCQCAPGYTGPHC 235
Score = 82.2 bits (194), Expect = 3e-14
Identities = 66/231 (28%), Positives = 91/231 (39%), Gaps = 33/231 (14%)
Query: 360 PCQCDPHFSTGNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNC-KPCTCNLNGTEGEH 417
PCQ F T G C C P + CS C G F PNC + C C+ G
Sbjct: 35 PCQNGGVFQT-----PQGSCSCPPGWMGTICSLPCPEG-FHGPNCSQECRCHNGGL---- 84
Query: 418 CTPTDGLCPCKYNYAGKSC-EICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSK 475
C G C C Y G C E C G + +C + C+C + C G C C+
Sbjct: 85 CDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC----APDARCFPANGACLCEHG 140
Query: 476 YSGRTCNQ--CQAGYYNYPTCKPCNCDTSGTEPSI-CDDVSGQCICKAGFGGPRCDQ-CL 531
++G C C G+Y PC CD E S+ C ++G+C C G+ G C++ C
Sbjct: 141 FTGDRCTDRLCPDGFYGLSCQAPCTCD---REHSLSCHPMNGECSCLPGWAGLHCNESCP 197
Query: 532 SGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSP 582
+ G + C+ + +TS G C C + G C P
Sbjct: 198 QDTHGP--GCQEHCLCLHGGVCQATS------GLCQCAPGYTGPHCASLCP 240
Score = 74.1 bits (174), Expect = 9e-12
Identities = 54/183 (29%), Positives = 71/183 (38%), Gaps = 26/183 (14%)
Query: 1357 GQCPCKPNVIGRTCS-ACRTGYYGFPNC-RPCHCPSTAICDD-NGMCICPKNVEGENC-D 1412
G C C P +G CS C G++G PNC + C C + +CD G C C G+ C +
Sbjct: 47 GSCSCPPGWMGTICSLPCPEGFHG-PNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCRE 105
Query: 1413 RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH--CVPGHY 1470
C F D CD C P +C +G C C G C C G Y
Sbjct: 106 ECPVGRFGQDCAETCD---CAP------DARCFPANGACLCEHGFTGDRCTDRLCPDGFY 156
Query: 1471 AFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYFNLQDDNPDGCTK- 1528
CTC+R + C +C C G C ++C QD + GC +
Sbjct: 157 GLSCQAPCTCDREHSL--SCHPMNGECSCLPGWAGLHCNESCP------QDTHGPGCQEH 208
Query: 1529 CFC 1531
C C
Sbjct: 209 CLC 211
Score = 71.7 bits (168), Expect = 5e-11
Identities = 69/234 (29%), Positives = 91/234 (38%), Gaps = 48/234 (20%)
Query: 1736 CQCPRAYRGLSCE-QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC- 1793
C CP + G C C EG + C+C+ + CD TG C CA GD C
Sbjct: 49 CSCPPGWMGTICSLPCPEGFHG--PNCSQECRCH-NGGLCDRFTGQC-RCAPGYTGDRCR 104
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC- 1852
E C G G T DC A +P+N +C C+ G+ G RC
Sbjct: 105 EECPVGRFGQDCAETC-DCAPDA--RCFPANG--------------ACLCEHGFTGDRCT 147
Query: 1853 -EYCAAGYYGIPEDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C G+YG+ C+ PC C + + SC +NG+C C+ AG C
Sbjct: 148 DRLCPDGFYGLS----------CQAPCTC----DREHSLSCHPMNGEC-SCLPGWAGLHC 192
Query: 1911 NLCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
N P C C+C G+ C +T+G C C PG G C P
Sbjct: 193 NESCP----QDTHGPGCQEHCLCLHGGV--CQATSGLCQCAPGYTGPHCASLCP 240
Score = 71.7 bits (168), Expect = 5e-11
Identities = 48/162 (29%), Positives = 61/162 (37%), Gaps = 16/162 (9%)
Query: 1352 CNTFGGQCPCKPNVIGRTC-SACRTGYYGFPNCRPCHCPSTAIC-DDNGMCICPKNVEGE 1409
C+ F GQC C P G C C G +G C C A C NG C+C G+
Sbjct: 85 CDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGD 144
Query: 1410 NC-DR-CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C DR C + Q C C+ + L C +G+C+C G C+ P
Sbjct: 145 RCTDRLCPDGFYGLSCQA---PCTCDR----EHSLSCHPMNGECSCLPGWAGLHCNESCP 197
Query: 1468 GHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
P C + C C HG VC + C C G C
Sbjct: 198 QDTHGPGCQEHCLC-LHG---GVCQATSGLCQCAPGYTGPHC 235
Score = 63.7 bits (148), Expect = 1e-08
Identities = 44/133 (33%), Positives = 63/133 (47%), Gaps = 17/133 (12%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHW-GLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTG 2003
G+C C PG +G C P+ + G N C N G+ CD GQCRCA G TG
Sbjct: 47 GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGL------CDRFTGQCRCAPGYTG 100
Query: 2004 KQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMC-NATGQCECLPGVIGEKC-DR-CPER 2059
+C ++C G + +D + C+C + C A G C C G G++C DR CP+
Sbjct: 101 DRCREECPVG--RFGQDCAETCDC----APDARCFPANGACLCEHGFTGDRCTDRLCPDG 154
Query: 2060 WVLIPQEGCLECD 2072
+ + + CD
Sbjct: 155 FYGLSCQAPCTCD 167
Score = 60.9 bits (141), Expect = 8e-08
Identities = 79/291 (27%), Positives = 101/291 (34%), Gaps = 65/291 (22%)
Query: 492 PTC-KPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC 550
P C KPC+C + S CD SG +GF P C +G Q C+C
Sbjct: 4 PQCDKPCSCGNN----SSCDPKSGGT---SGFFCPSTHPCQNGGVFQTPQGS-----CSC 51
Query: 551 DPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NG 609
P G T CS C F G C Q C C G CD G
Sbjct: 52 PP-GWMGTICSLP----CPEGFHGPNCSQ------------ECRCHNGG----LCDRFTG 90
Query: 610 LCHCKSNFDGAKC-DTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQ 668
C C + G +C + C + E C+C P A C PA C C+
Sbjct: 91 QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPD------ARC--FPANGACLCEHGFT 142
Query: 669 GRICND--CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
G C D C ++ L P C C+ +L+ C+ +G+C C C+
Sbjct: 143 GDRCTDRLCPDGFYGLSCQAP-----CTCDREHSLS----CHPMNGECSCLPGWAGLHCN 193
Query: 727 QCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+ Q GC E C C GG C T+G C C G C
Sbjct: 194 ESCP-----QDTHGPGCQEHCLCLHGGV----CQATSGLCQCAPGYTGPHC 235
Score = 50.0 bits (114), Expect = 2e-04
Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 15/120 (12%)
Query: 319 YEGGGKCLNCQHNTEGINC-NKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG 377
+ G CL C+H G C ++ P + YG L PC CD S +C +G
Sbjct: 129 FPANGACL-CEHGFTGDRCTDRLCPDGF--YG-----LSCQAPCTCDREHSL-SCHPMNG 179
Query: 378 RCECRPEFQPPDCSSCAYGYFDYPNCKP-CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC 436
C C P + C+ P C+ C C G C T GLC C Y G C
Sbjct: 180 ECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGV----CQATSGLCQCAPGYTGPHC 235
Score = 46.8 bits (106), Expect = 0.001
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-ACRTGYYGFPNCRP-CHCPSTAICD- 1395
PC CD S L C+ G+C C P G C+ +C +G P C+ C C +C
Sbjct: 163 PCTCDREHS--LSCHPMNGECSCLPGWAGLHCNESCPQDTHG-PGCQEHCLCLHGGVCQA 219
Query: 1396 DNGMCICPKNVEGENC-DRCKP 1416
+G+C C G +C C P
Sbjct: 220 TSGLCQCAPGYTGPHCASLCPP 241
Score = 46.0 bits (104), Expect = 0.003
Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 15/125 (12%)
Query: 1349 ELECNTFGGQCPCKPNVIGRTCS--ACRTGYYGFPNCRPCHCP---STAICDDNGMCICP 1403
+ C G C C+ G C+ C G+YG PC C S + NG C C
Sbjct: 125 DARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCL 184
Query: 1404 KNVEGENCDRCKPYTFNFDVQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVC 1462
G +C+ P + GC + C C GV C+A SG C C G C
Sbjct: 185 PGWAGLHCNESCPQDTHGP---GCQEHCLCLHGGV------CQATSGLCQCAPGYTGPHC 235
Query: 1463 DHCVP 1467
P
Sbjct: 236 ASLCP 240
Score = 43.2 bits (97), Expect = 0.018
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
Query: 1445 EADSGKCACRENVRGRVCDHCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNV 1503
+ G C+C G +C P + P+C Q C C+ G +CD+ T QC C
Sbjct: 43 QTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG----LCDRFTGQCRCAPGY 98
Query: 1504 RGQACDTCKEE 1514
G D C+EE
Sbjct: 99 TG---DRCREE 106
>X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein.
Length = 2201
Score = 94.3 bits (224), Expect = 7e-18
Identities = 123/472 (26%), Positives = 174/472 (36%), Gaps = 77/472 (16%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNC--KPCTCNLNGTEGEHCTPTDGLC 425
GN E C C P ++ P+CS C C C C+ +G GE C+ C
Sbjct: 165 GNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICD-DGFTGEDCSQL--AC 221
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSY-VCDKLTGDCTCKSKYSGRTC 481
P N GK IC +GY +C C S + C + G C C ++G C
Sbjct: 222 PSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTC--VDGLCVCHDGFAGDDC 279
Query: 482 NQ--CQAGYYNYPTC--KPCNCDTSGTE--------PSICDD----VSGQCICKAGFGGP 525
N+ C YN C C CD T P+ C D ++G C C+ GF G
Sbjct: 280 NKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGE 339
Query: 526 RCDQ--CLSGYYMQVLGRERQCV------PCNCD----PTGSTSTSCSADGKCNCLTNFG 573
C + C + Q E QCV +C P + DG+C C F
Sbjct: 340 DCGKPTCPHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFT 399
Query: 574 GAQCDQ--CSPGYYKYPDCLS--CNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCR 626
GA C + C G + C++ C CD G G C CH + KC C
Sbjct: 400 GADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLRCPNDCHSRGRCVEGKC-VCE 457
Query: 627 EQFYNYPACE-EC--NCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICND---CKPLY 679
+ F Y + C +C G C GE C+DR R C++ C
Sbjct: 458 QGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGE--DCRDRQCPRDCSNRGLCVDGQ 515
Query: 680 WNLQE-YNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG----ERQCDQCLDGFY 733
++ + C + +C + G C +GQCVC + +G E++C G
Sbjct: 516 CVCEDGFTGPDCAELSC--PNDCHGQGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQG 571
Query: 734 RLQTNDVF---GCTECDCDIGGSIDNNCDK----TTGQCHCHSRVEGRRCDQ 778
R G T DC S ++C+ +G+C C+ G C +
Sbjct: 572 RCVDGQCICHEGFTGLDCG-QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 622
Score = 79.8 bits (188), Expect = 2e-13
Identities = 110/429 (25%), Positives = 157/429 (36%), Gaps = 86/429 (20%)
Query: 227 IGGRCMC-NGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
+ G C+C G+A AD + + + C +H TC C GF + ++
Sbjct: 232 VNGVCICFEGYAG----ADCSREICPVPCSEEHGTCVDGLCVCHDGFA------GDDCNK 281
Query: 286 FSCEPCNCHNH----TTECTYDPEIDEKRLSLDI--NGRYEGGGKCLN----CQHNTEGI 335
C NC+N EC D + S I N ++ G +C+N C+ G
Sbjct: 282 PLCLN-NCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRG-RCINGTCYCEEGFTGE 339
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE-------------SGRCECR 382
+C K PT P+ C CD F+ +C E+ GRCEC
Sbjct: 340 DCGK--PTC--PHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECD 395
Query: 383 PEFQPPDCSS--CAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
F DC C G + C C C+ G GE C+ CP + G+ E
Sbjct: 396 DGFTGADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLR--CPNDCHSRGRCVEG 452
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK 495
+CE G+ +C + C C + G C C Y+G C Q
Sbjct: 453 KCVCEQGFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRDRQC--------- 501
Query: 496 PCNCDTSGTEPSICDDVSGQCICKAGFGGPRC------------DQCLSGYYMQVLG-RE 542
P +C G +C V GQC+C+ GF GP C +C++G + G
Sbjct: 502 PRDCSNRG----LC--VDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMG 555
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLS--CNCDVS 598
+ C C P+ DG+C C F G C Q C C+S C C+
Sbjct: 556 KDCKEQRC-PSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICN-E 613
Query: 599 GSIGSTCDD 607
G G C +
Sbjct: 614 GYSGEDCSE 622
Score = 64.1 bits (149), Expect = 9e-09
Identities = 92/329 (27%), Positives = 118/329 (35%), Gaps = 73/329 (22%)
Query: 470 CTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C+ + +S C C+ G+ P C C + C D GQCIC GF G C
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKG-PNCSEPECPGNCHLRGRCID--GQCICDDGFTGEDCS 217
Query: 529 QCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP 588
Q P +C+ G C +G C C + GA C +
Sbjct: 218 QL--------------ACPSDCNDQG----KC-VNGVCICFEGYAGADCSR--------- 249
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPAC--EECNCDPRG 644
C S G TC D GLC C F G C+ C YN C EC CD G
Sbjct: 250 --EICPVPCSEEHG-TCVD-GLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCD-EG 304
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
T C + C DR GR N Y + + C + C A ++
Sbjct: 305 FTGE--DCSELICPN--DCFDR--GRCING--TCYCE-EGFTGEDCGKPTCPHA--CHTQ 353
Query: 705 GACNTKSGQCVCKQ-----HVGERQC-------DQCLDGFYRLQTNDVF---GCTECDCD 749
G C + GQCVC + E++C +C+DG R + +D F C E C
Sbjct: 354 GRC--EEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDG--RCECDDGFTGADCGELKCP 409
Query: 750 IGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G S C GQC C G C Q
Sbjct: 410 NGCSGHGRC--VNGQCVCDEGYTGEDCSQ 436
Score = 58.0 bits (134), Expect = 6e-07
Identities = 103/398 (25%), Positives = 133/398 (33%), Gaps = 93/398 (23%)
Query: 1736 CQCPRAYRGLSCEQ------CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNT- 1788
C C Y G C + C+E H G CV C D C N +CLN N
Sbjct: 236 CICFEGYAGADCSREICPVPCSEEHGTCVDGLCV-CHDGFAGDDC--NKPLCLNNCYNRG 292
Query: 1789 --IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-----SCD 1831
+ + C C G+ G+ + + P DC C C + + +C
Sbjct: 293 RCVENEC-VCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH 351
Query: 1832 LSENGSLISCNCQPGYGGARC--EYCAAGYY-------GIPEDTDLHTGDYCKPCNCSGN 1882
C C G+ G C + C A + G E D TG C C
Sbjct: 352 TQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG 411
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCTA--CICDE-FGMA 1938
+ G C +NG C+ C G C+ L P D C C+C++ F
Sbjct: 412 CSGH--GRC--VNGQCV-CDEGYTGEDCSQLRCPN---DCHSRGRCVEGKCVCEQGFKGY 463
Query: 1939 DCDSTT-------------GTCVCRPGVIGEKC-DRCAPDHWGLNTGL----------GC 1974
DC + G CVC G GE C DR P N GL G
Sbjct: 464 DCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCS-NRGLCVDGQCVCEDGF 522
Query: 1975 TPCNCGIASESTQCDDD----NGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNT 2028
T +C S C NGQC C +G GK C +C + + C C+
Sbjct: 523 TGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHE 582
Query: 2029 GY--------SVGFMCNATGQCE-----CLPGVIGEKC 2053
G+ S CN GQC C G GE C
Sbjct: 583 GFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDC 620
Score = 57.6 bits (133), Expect = 8e-07
Identities = 94/358 (26%), Positives = 127/358 (35%), Gaps = 65/358 (18%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQC---NGHSDQCDVNTGICLNCADN--TI 1789
C C ++G +C E G+ L G C+ QC +G + + +C D +
Sbjct: 174 CVCEPGWKGPNCSEPECPGNCHL-RGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCV 232
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS--CNCQPGY 1847
C C GY G DC CP+P C E+G+ + C C G+
Sbjct: 233 NGVC-ICFEGYAG-------ADCSREICPVP---------CS-EEHGTCVDGLCVCHDGF 274
Query: 1848 GGARCE--YCAAGYY--GIPEDTDLHTGDYCKPCNCSGNINPQD---PGSCDSINGDCLK 1900
G C C Y G + + + +CS I P D G C ING C
Sbjct: 275 AGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCY- 331
Query: 1901 CVNNTAGAACN--LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
C G C C + + C+CDE G A D + C G
Sbjct: 332 CEEGFTGEDCGKPTCPHACHTQGRCEEG--QCVCDE-GFAGLDCSEKRCPADCHNRGRCV 388
Query: 1959 D-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
D RC D G C G + +C NGQC C +G TG+ C Q ++
Sbjct: 389 DGRCECDDGFTGADCGELKCPNGCSGHG-RCV--NGQCVCDEGYTGEDCSQLRCPNDCHS 445
Query: 2018 KDGC--DHCNCNTGYSVGFMCN--------------ATGQCECLPGVIGEKC-DR-CP 2057
+ C C C G+ G+ C+ G C C G GE C DR CP
Sbjct: 446 RGRCVEGKCVCEQGFK-GYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCP 502
Score = 51.2 bits (117), Expect = 7e-05
Identities = 70/275 (25%), Positives = 105/275 (38%), Gaps = 55/275 (20%)
Query: 1735 ECQCPRAYRGLSCEQ--C-AEGHYRLPSGFCVP--CQCNGHSDQCDVNTGICLN-CADN- 1787
+C C + GL C + C A+ H R G CV C+C+ D C N C+ +
Sbjct: 360 QCVCDEGFAGLDCSEKRCPADCHNR---GRCVDGRCECDDGFTGADCGELKCPNGCSGHG 416
Query: 1788 -TIGDHCEFCMSGYHGD--ATVGTPRDCLI--------CACPMPYPSNNFA-LSC--DLS 1833
+ C C GY G+ + + P DC C C + + + +SC D
Sbjct: 417 RCVNGQC-VCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCH 475
Query: 1834 ENGSLIS--CNCQPGYGGARCE--YCA--AGYYGIPED-----TDLHTGDYCKPCNCSGN 1882
++G ++ C C GY G C C G+ D D TG C +C +
Sbjct: 476 QHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND 535
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDA-------IFSKNCTACICD 1933
+ Q G C +NG C+ C G C C +G I + T C
Sbjct: 536 CHGQ--GRC--VNGQCV-CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590
Query: 1934 EFGM-ADCDS----TTGTCVCRPGVIGEKCDRCAP 1963
+ +DC++ +G C+C G GE C +P
Sbjct: 591 QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSP 625
Score = 48.4 bits (110), Expect = 5e-04
Identities = 56/200 (28%), Positives = 77/200 (38%), Gaps = 31/200 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G T +C+ +CP + GR C G+ G+ +C CP+
Sbjct: 423 CVCD-EGYTGEDCSQL--RCPNDCHSRGRCVEGKCVCEQGFKGY-DCSDMSCPNDCHQHG 478
Query: 1397 ---NGMCICPKNVEGENC-DR-----CKPYTFNFDVQRGCDD----CNCNPLGVVGN-QL 1442
NGMC+C GE+C DR C D Q C+D +C L +
Sbjct: 479 RCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHG 538
Query: 1443 QCEADSGKCACRENVRGRVC--DHCVPGHYAFPDCY--QCTCNRHGTTYDVCDQNTAQCY 1498
Q +G+C C E G+ C C + C QC C+ T D C Q++
Sbjct: 539 QGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLD-CGQHSCPSD 597
Query: 1499 CKTNVRGQACD---TCKEEY 1515
C N GQ C E Y
Sbjct: 598 C--NNLGQCVSGRCICNEGY 615
Score = 41.9 bits (94), Expect = 0.042
Identities = 60/220 (27%), Positives = 83/220 (37%), Gaps = 32/220 (14%)
Query: 1305 EQC-ASYNYYISPNETGLCREAMFSITSEYNSGARPCLCD--FMGS--TELECNTFGGQC 1359
EQC A + P L S +++ C+C+ + G +E EC G C
Sbjct: 138 EQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECP---GNC 194
Query: 1360 PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDRC 1414
+ I C C G+ G +C CPS C+D NG+CIC + G +C R
Sbjct: 195 HLRGRCIDGQC-ICDDGFTG-EDCSQLACPSD--CNDQGKCVNGVCICFEGYAGADCSRE 250
Query: 1415 KPYTFNFDVQRGCDD--CNCNPLGVVGNQLQCEADSGKCACRENV--RGR-VCDHCVPGH 1469
+ C D C C+ G G+ D K C N RGR V + CV
Sbjct: 251 ICPVPCSEEHGTCVDGLCVCHD-GFAGD------DCNKPLCLNNCYNRGRCVENECVCDE 303
Query: 1470 -YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ DC + C C T CYC+ G+ C
Sbjct: 304 GFTGEDCSELICPNDCFDRGRCINGT--CYCEEGFTGEDC 341
Score = 41.1 bits (92), Expect = 0.073
Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 29/149 (19%)
Query: 1340 CLCDFMGSTELECNTFGGQCP--CKPN--VIGRTCSACRTGYYGFPNCRPCHCPSTAICD 1395
C+CD G T +C QCP C + C C G+ G P+C CP+
Sbjct: 485 CVCDD-GYTGEDCRD--RQCPRDCSNRGLCVDGQC-VCEDGFTG-PDCAELSCPNDCHGQ 539
Query: 1396 D---NGMCICPKNVEGENC--DRCKPYTFNFDVQRGCDD--CNCNP--LGVVGNQLQCEA 1446
NG C+C + G++C RC Q C D C C+ G+ Q C +
Sbjct: 540 GRCVNGQCVCHEGFMGKDCKEQRCPSDCHG---QGRCVDGQCICHEGFTGLDCGQHSCPS 596
Query: 1447 D--------SGKCACRENVRGRVCDHCVP 1467
D SG+C C E G C P
Sbjct: 597 DCNNLGQCVSGRCICNEGYSGEDCSEVSP 625
Score = 39.1 bits (87), Expect = 0.30
Identities = 60/237 (25%), Positives = 85/237 (35%), Gaps = 36/237 (15%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD 607
C TG T G+ N T G C C PG+ K P+C C + + C D
Sbjct: 147 CLQPATGRLDTRPFCSGRGNFSTE--GCGC-VCEPGW-KGPNCSEPECPGNCHLRGRCID 202
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAG-CGSVPAGELCQCKDR 666
G C C F G C Q C + GV F G G+ + E+C
Sbjct: 203 -GQCICDDGFTGEDCS----QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCS 257
Query: 667 VQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
+ C D + ++ F + CN L L C + G+CV E +C
Sbjct: 258 EEHGTCVDGLCVC-----HDGFAGDDCNKPLC-----LNNCYNR-GRCV------ENEC- 299
Query: 727 QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
C +GF +++ +C D G I+ G C+C G C +P H
Sbjct: 300 VCDEGFTGEDCSELICPNDC-FDRGRCIN-------GTCYCEEGFTGEDCGKPTCPH 348
Score = 38.7 bits (86), Expect = 0.39
Identities = 46/177 (25%), Positives = 66/177 (37%), Gaps = 18/177 (10%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G L+C+ +CP + GR C G+ G +C CP+
Sbjct: 361 CVCD-EGFAGLDCSE--KRCPADCHNRGRCVDGRCECDDGFTG-ADCGELKCPNGCSGHG 416
Query: 1397 ---NGMCICPKNVEGENCDRCK-PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
NG C+C + GE+C + + P + + C C G G C S
Sbjct: 417 RCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQ-GFKG--YDCSDMSCPND 473
Query: 1453 CRENVRGRVCDHCV-PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C ++ R V CV Y DC C R + +C QC C+ G C
Sbjct: 474 CHQHGR-CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD--GQCVCEDGFTGPDC 527
Score = 36.7 bits (81), Expect = 1.6
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDR-CKPYTFNFDVQRG 1426
C G+ G +C CP+ C D NG C C + GE+C + P+ + Q
Sbjct: 301 CDEGFTG-EDCSELICPND--CFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH--TQGR 355
Query: 1427 CDD--CNCNP--LGVVGNQLQCEAD--------SGKCACRENVRGRVCDH--CVPGHYAF 1472
C++ C C+ G+ ++ +C AD G+C C + G C C G
Sbjct: 356 CEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGH 415
Query: 1473 PDCY--QCTCNRHGTTYDVCDQ 1492
C QC C+ G T + C Q
Sbjct: 416 GRCVNGQCVCD-EGYTGEDCSQ 436
>M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein.
Length = 2203
Score = 94.3 bits (224), Expect = 7e-18
Identities = 123/472 (26%), Positives = 174/472 (36%), Gaps = 77/472 (16%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNC--KPCTCNLNGTEGEHCTPTDGLC 425
GN E C C P ++ P+CS C C C C+ +G GE C+ C
Sbjct: 165 GNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICD-DGFTGEDCSQL--AC 221
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSY-VCDKLTGDCTCKSKYSGRTC 481
P N GK IC +GY +C C S + C + G C C ++G C
Sbjct: 222 PSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTC--VDGLCVCHDGFAGDDC 279
Query: 482 NQ--CQAGYYNYPTC--KPCNCDTSGTE--------PSICDD----VSGQCICKAGFGGP 525
N+ C YN C C CD T P+ C D ++G C C+ GF G
Sbjct: 280 NKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGE 339
Query: 526 RCDQ--CLSGYYMQVLGRERQCV------PCNCD----PTGSTSTSCSADGKCNCLTNFG 573
C + C + Q E QCV +C P + DG+C C F
Sbjct: 340 DCGKPTCPHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFT 399
Query: 574 GAQCDQ--CSPGYYKYPDCLS--CNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCR 626
GA C + C G + C++ C CD G G C CH + KC C
Sbjct: 400 GADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLRCPNDCHSRGRCVEGKC-VCE 457
Query: 627 EQFYNYPACE-EC--NCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICND---CKPLY 679
+ F Y + C +C G C GE C+DR R C++ C
Sbjct: 458 QGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGE--DCRDRQCPRDCSNRGLCVDGQ 515
Query: 680 WNLQE-YNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG----ERQCDQCLDGFY 733
++ + C + +C + G C +GQCVC + +G E++C G
Sbjct: 516 CVCEDGFTGPDCAELSC--PNDCHGRGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQG 571
Query: 734 RLQTNDVF---GCTECDCDIGGSIDNNCDK----TTGQCHCHSRVEGRRCDQ 778
R G T DC S ++C+ +G+C C+ G C +
Sbjct: 572 RCVDGQCICHEGFTGLDCG-QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 622
Score = 79.8 bits (188), Expect = 2e-13
Identities = 110/429 (25%), Positives = 157/429 (36%), Gaps = 86/429 (20%)
Query: 227 IGGRCMC-NGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
+ G C+C G+A AD + + + C +H TC C GF + ++
Sbjct: 232 VNGVCICFEGYAG----ADCSREICPVPCSEEHGTCVDGLCVCHDGFA------GDDCNK 281
Query: 286 FSCEPCNCHNH----TTECTYDPEIDEKRLSLDI--NGRYEGGGKCLN----CQHNTEGI 335
C NC+N EC D + S I N ++ G +C+N C+ G
Sbjct: 282 PLCLN-NCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRG-RCINGTCYCEEGFTGE 339
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE-------------SGRCECR 382
+C K PT P+ C CD F+ +C E+ GRCEC
Sbjct: 340 DCGK--PTC--PHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECD 395
Query: 383 PEFQPPDCSS--CAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
F DC C G + C C C+ G GE C+ CP + G+ E
Sbjct: 396 DGFTGADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLR--CPNDCHSRGRCVEG 452
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK 495
+CE G+ +C + C C + G C C Y+G C Q
Sbjct: 453 KCVCEQGFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRDRQC--------- 501
Query: 496 PCNCDTSGTEPSICDDVSGQCICKAGFGGPRC------------DQCLSGYYMQVLG-RE 542
P +C G +C V GQC+C+ GF GP C +C++G + G
Sbjct: 502 PRDCSNRG----LC--VDGQCVCEDGFTGPDCAELSCPNDCHGRGRCVNGQCVCHEGFMG 555
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLS--CNCDVS 598
+ C C P+ DG+C C F G C Q C C+S C C+
Sbjct: 556 KDCKEQRC-PSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICN-E 613
Query: 599 GSIGSTCDD 607
G G C +
Sbjct: 614 GYSGEDCSE 622
Score = 64.1 bits (149), Expect = 9e-09
Identities = 92/329 (27%), Positives = 118/329 (35%), Gaps = 73/329 (22%)
Query: 470 CTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C+ + +S C C+ G+ P C C + C D GQCIC GF G C
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKG-PNCSEPECPGNCHLRGRCID--GQCICDDGFTGEDCS 217
Query: 529 QCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP 588
Q P +C+ G C +G C C + GA C +
Sbjct: 218 QL--------------ACPSDCNDQG----KC-VNGVCICFEGYAGADCSR--------- 249
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPAC--EECNCDPRG 644
C S G TC D GLC C F G C+ C YN C EC CD G
Sbjct: 250 --EICPVPCSEEHG-TCVD-GLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCD-EG 304
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
T C + C DR GR N Y + + C + C A ++
Sbjct: 305 FTGE--DCSELICPN--DCFDR--GRCING--TCYCE-EGFTGEDCGKPTCPHA--CHTQ 353
Query: 705 GACNTKSGQCVCKQ-----HVGERQC-------DQCLDGFYRLQTNDVF---GCTECDCD 749
G C + GQCVC + E++C +C+DG R + +D F C E C
Sbjct: 354 GRC--EEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDG--RCECDDGFTGADCGELKCP 409
Query: 750 IGGSIDNNCDKTTGQCHCHSRVEGRRCDQ 778
G S C GQC C G C Q
Sbjct: 410 NGCSGHGRC--VNGQCVCDEGYTGEDCSQ 436
Score = 58.0 bits (134), Expect = 6e-07
Identities = 103/398 (25%), Positives = 133/398 (33%), Gaps = 93/398 (23%)
Query: 1736 CQCPRAYRGLSCEQ------CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNT- 1788
C C Y G C + C+E H G CV C D C N +CLN N
Sbjct: 236 CICFEGYAGADCSREICPVPCSEEHGTCVDGLCV-CHDGFAGDDC--NKPLCLNNCYNRG 292
Query: 1789 --IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-----SCD 1831
+ + C C G+ G+ + + P DC C C + + +C
Sbjct: 293 RCVENEC-VCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH 351
Query: 1832 LSENGSLISCNCQPGYGGARC--EYCAAGYY-------GIPEDTDLHTGDYCKPCNCSGN 1882
C C G+ G C + C A + G E D TG C C
Sbjct: 352 TQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG 411
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCTA--CICDE-FGMA 1938
+ G C +NG C+ C G C+ L P D C C+C++ F
Sbjct: 412 CSGH--GRC--VNGQCV-CDEGYTGEDCSQLRCPN---DCHSRGRCVEGKCVCEQGFKGY 463
Query: 1939 DCDSTT-------------GTCVCRPGVIGEKC-DRCAPDHWGLNTGL---GCTPCNCGI 1981
DC + G CVC G GE C DR P N GL G C G
Sbjct: 464 DCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCS-NRGLCVDGQCVCEDGF 522
Query: 1982 ASEST---QCDDD--------NGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNT 2028
C +D NGQC C +G GK C +C + + C C+
Sbjct: 523 TGPDCAELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHE 582
Query: 2029 GY--------SVGFMCNATGQCE-----CLPGVIGEKC 2053
G+ S CN GQC C G GE C
Sbjct: 583 GFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDC 620
Score = 57.6 bits (133), Expect = 8e-07
Identities = 94/358 (26%), Positives = 127/358 (35%), Gaps = 65/358 (18%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQC---NGHSDQCDVNTGICLNCADN--TI 1789
C C ++G +C E G+ L G C+ QC +G + + +C D +
Sbjct: 174 CVCEPGWKGPNCSEPECPGNCHL-RGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCV 232
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS--CNCQPGY 1847
C C GY G DC CP+P C E+G+ + C C G+
Sbjct: 233 NGVC-ICFEGYAG-------ADCSREICPVP---------CS-EEHGTCVDGLCVCHDGF 274
Query: 1848 GGARCE--YCAAGYY--GIPEDTDLHTGDYCKPCNCSGNINPQD---PGSCDSINGDCLK 1900
G C C Y G + + + +CS I P D G C ING C
Sbjct: 275 AGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCY- 331
Query: 1901 CVNNTAGAACN--LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
C G C C + + C+CDE G A D + C G
Sbjct: 332 CEEGFTGEDCGKPTCPHACHTQGRCEEG--QCVCDE-GFAGLDCSEKRCPADCHNRGRCV 388
Query: 1959 D-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
D RC D G C G + +C NGQC C +G TG+ C Q ++
Sbjct: 389 DGRCECDDGFTGADCGELKCPNGCSGHG-RCV--NGQCVCDEGYTGEDCSQLRCPNDCHS 445
Query: 2018 KDGC--DHCNCNTGYSVGFMCN--------------ATGQCECLPGVIGEKC-DR-CP 2057
+ C C C G+ G+ C+ G C C G GE C DR CP
Sbjct: 446 RGRCVEGKCVCEQGFK-GYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCP 502
Score = 49.6 bits (113), Expect = 2e-04
Identities = 69/275 (25%), Positives = 105/275 (38%), Gaps = 55/275 (20%)
Query: 1735 ECQCPRAYRGLSCEQ--C-AEGHYRLPSGFCVP--CQCNGHSDQCDVNTGICLN-CADN- 1787
+C C + GL C + C A+ H R G CV C+C+ D C N C+ +
Sbjct: 360 QCVCDEGFAGLDCSEKRCPADCHNR---GRCVDGRCECDDGFTGADCGELKCPNGCSGHG 416
Query: 1788 -TIGDHCEFCMSGYHGD--ATVGTPRDCLI--------CACPMPYPSNNFA-LSC--DLS 1833
+ C C GY G+ + + P DC C C + + + +SC D
Sbjct: 417 RCVNGQC-VCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCH 475
Query: 1834 ENGSLIS--CNCQPGYGGARCE--YCA--AGYYGIPED-----TDLHTGDYCKPCNCSGN 1882
++G ++ C C GY G C C G+ D D TG C +C +
Sbjct: 476 QHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND 535
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDA-------IFSKNCTACICD 1933
+ + G C +NG C+ C G C C +G I + T C
Sbjct: 536 CHGR--GRC--VNGQCV-CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590
Query: 1934 EFGM-ADCDS----TTGTCVCRPGVIGEKCDRCAP 1963
+ +DC++ +G C+C G GE C +P
Sbjct: 591 QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSP 625
Score = 48.0 bits (109), Expect = 6e-04
Identities = 60/204 (29%), Positives = 80/204 (39%), Gaps = 39/204 (19%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G T +C+ +CP + GR C G+ G+ +C CP+
Sbjct: 423 CVCD-EGYTGEDCSQL--RCPNDCHSRGRCVEGKCVCEQGFKGY-DCSDMSCPNDCHQHG 478
Query: 1397 ---NGMCICPKNVEGENC-DRCKPYTFNFDVQRG-CDD--CNCNPLGVVG---NQLQCEA 1446
NGMC+C GE+C DR P + RG C D C C G G +L C
Sbjct: 479 RCVNGMCVCDDGYTGEDCRDRQCPRDCS---NRGLCVDGQCVCED-GFTGPDCAELSCPN 534
Query: 1447 D--------SGKCACRENVRGRVC--DHCVPGHYAFPDCY--QCTCNRHGTTYDVCDQNT 1494
D +G+C C E G+ C C + C QC C+ T D C Q++
Sbjct: 535 DCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLD-CGQHS 593
Query: 1495 AQCYCKTNVRGQACD---TCKEEY 1515
C N GQ C E Y
Sbjct: 594 CPSDC--NNLGQCVSGRCICNEGY 615
Score = 41.9 bits (94), Expect = 0.042
Identities = 60/220 (27%), Positives = 83/220 (37%), Gaps = 32/220 (14%)
Query: 1305 EQC-ASYNYYISPNETGLCREAMFSITSEYNSGARPCLCD--FMGS--TELECNTFGGQC 1359
EQC A + P L S +++ C+C+ + G +E EC G C
Sbjct: 138 EQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECP---GNC 194
Query: 1360 PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDRC 1414
+ I C C G+ G +C CPS C+D NG+CIC + G +C R
Sbjct: 195 HLRGRCIDGQC-ICDDGFTG-EDCSQLACPSD--CNDQGKCVNGVCICFEGYAGADCSRE 250
Query: 1415 KPYTFNFDVQRGCDD--CNCNPLGVVGNQLQCEADSGKCACRENV--RGR-VCDHCVPGH 1469
+ C D C C+ G G+ D K C N RGR V + CV
Sbjct: 251 ICPVPCSEEHGTCVDGLCVCHD-GFAGD------DCNKPLCLNNCYNRGRCVENECVCDE 303
Query: 1470 -YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ DC + C C T CYC+ G+ C
Sbjct: 304 GFTGEDCSELICPNDCFDRGRCINGT--CYCEEGFTGEDC 341
Score = 40.3 bits (90), Expect = 0.13
Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 29/149 (19%)
Query: 1340 CLCDFMGSTELECNTFGGQCP--CKPN--VIGRTCSACRTGYYGFPNCRPCHCPSTAICD 1395
C+CD G T +C QCP C + C C G+ G P+C CP+
Sbjct: 485 CVCDD-GYTGEDCRD--RQCPRDCSNRGLCVDGQC-VCEDGFTG-PDCAELSCPNDCHGR 539
Query: 1396 D---NGMCICPKNVEGENC--DRCKPYTFNFDVQRGCDD--CNCNP--LGVVGNQLQCEA 1446
NG C+C + G++C RC Q C D C C+ G+ Q C +
Sbjct: 540 GRCVNGQCVCHEGFMGKDCKEQRCPSDCHG---QGRCVDGQCICHEGFTGLDCGQHSCPS 596
Query: 1447 D--------SGKCACRENVRGRVCDHCVP 1467
D SG+C C E G C P
Sbjct: 597 DCNNLGQCVSGRCICNEGYSGEDCSEVSP 625
Score = 39.1 bits (87), Expect = 0.30
Identities = 60/237 (25%), Positives = 85/237 (35%), Gaps = 36/237 (15%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD 607
C TG T G+ N T G C C PG+ K P+C C + + C D
Sbjct: 147 CLQPATGRLDTRPFCSGRGNFSTE--GCGC-VCEPGW-KGPNCSEPECPGNCHLRGRCID 202
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAG-CGSVPAGELCQCKDR 666
G C C F G C Q C + GV F G G+ + E+C
Sbjct: 203 -GQCICDDGFTGEDCS----QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCS 257
Query: 667 VQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
+ C D + ++ F + CN L L C + G+CV E +C
Sbjct: 258 EEHGTCVDGLCVC-----HDGFAGDDCNKPLC-----LNNCYNR-GRCV------ENEC- 299
Query: 727 QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
C +GF +++ +C D G I+ G C+C G C +P H
Sbjct: 300 VCDEGFTGEDCSELICPNDC-FDRGRCIN-------GTCYCEEGFTGEDCGKPTCPH 348
Score = 38.7 bits (86), Expect = 0.39
Identities = 46/177 (25%), Positives = 66/177 (37%), Gaps = 18/177 (10%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G L+C+ +CP + GR C G+ G +C CP+
Sbjct: 361 CVCD-EGFAGLDCSE--KRCPADCHNRGRCVDGRCECDDGFTG-ADCGELKCPNGCSGHG 416
Query: 1397 ---NGMCICPKNVEGENCDRCK-PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
NG C+C + GE+C + + P + + C C G G C S
Sbjct: 417 RCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQ-GFKG--YDCSDMSCPND 473
Query: 1453 CRENVRGRVCDHCV-PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C ++ R V CV Y DC C R + +C QC C+ G C
Sbjct: 474 CHQHGR-CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD--GQCVCEDGFTGPDC 527
Score = 36.7 bits (81), Expect = 1.6
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDR-CKPYTFNFDVQRG 1426
C G+ G +C CP+ C D NG C C + GE+C + P+ + Q
Sbjct: 301 CDEGFTG-EDCSELICPND--CFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH--TQGR 355
Query: 1427 CDD--CNCNP--LGVVGNQLQCEAD--------SGKCACRENVRGRVCDH--CVPGHYAF 1472
C++ C C+ G+ ++ +C AD G+C C + G C C G
Sbjct: 356 CEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGH 415
Query: 1473 PDCY--QCTCNRHGTTYDVCDQ 1492
C QC C+ G T + C Q
Sbjct: 416 GRCVNGQCVCD-EGYTGEDCSQ 436
>AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachion)
protein.
Length = 2201
Score = 94.3 bits (224), Expect = 7e-18
Identities = 123/472 (26%), Positives = 174/472 (36%), Gaps = 77/472 (16%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNC--KPCTCNLNGTEGEHCTPTDGLC 425
GN E C C P ++ P+CS C C C C+ +G GE C+ C
Sbjct: 165 GNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICD-DGFTGEDCSQL--AC 221
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSY-VCDKLTGDCTCKSKYSGRTC 481
P N GK IC +GY +C C S + C + G C C ++G C
Sbjct: 222 PSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTC--VDGLCVCHDGFAGDDC 279
Query: 482 NQ--CQAGYYNYPTC--KPCNCDTSGTE--------PSICDD----VSGQCICKAGFGGP 525
N+ C YN C C CD T P+ C D ++G C C+ GF G
Sbjct: 280 NKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGE 339
Query: 526 RCDQ--CLSGYYMQVLGRERQCV------PCNCD----PTGSTSTSCSADGKCNCLTNFG 573
C + C + Q E QCV +C P + DG+C C F
Sbjct: 340 DCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFT 399
Query: 574 GAQCDQ--CSPGYYKYPDCLS--CNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCR 626
GA C + C G + C++ C CD G G C CH + KC C
Sbjct: 400 GADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLRCPNDCHSRGRCVEGKC-VCE 457
Query: 627 EQFYNYPACE-EC--NCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICND---CKPLY 679
+ F Y + C +C G C GE C+DR R C++ C
Sbjct: 458 QGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGE--DCRDRQCPRDCSNRGLCVDGQ 515
Query: 680 WNLQE-YNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG----ERQCDQCLDGFY 733
++ + C + +C + G C +GQCVC + +G E++C G
Sbjct: 516 CVCEDGFTGPDCAELSC--PNDCHGQGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQG 571
Query: 734 RLQTNDVF---GCTECDCDIGGSIDNNCDK----TTGQCHCHSRVEGRRCDQ 778
R G T DC S ++C+ +G+C C+ G C +
Sbjct: 572 RCVDGQCICHEGFTGLDCG-QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 622
Score = 80.2 bits (189), Expect = 1e-13
Identities = 110/429 (25%), Positives = 157/429 (36%), Gaps = 86/429 (20%)
Query: 227 IGGRCMC-NGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
+ G C+C G+A AD + + + C +H TC C GF + ++
Sbjct: 232 VNGVCICFEGYAG----ADCSREICPVPCSEEHGTCVDGLCVCHDGFA------GDDCNK 281
Query: 286 FSCEPCNCHNH----TTECTYDPEIDEKRLSLDI--NGRYEGGGKCLN----CQHNTEGI 335
C NC+N EC D + S I N ++ G +C+N C+ G
Sbjct: 282 PLCLN-NCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRG-RCINGTCYCEEGFTGE 339
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE-------------SGRCECR 382
+C K PT P+ C CD F+ +C E+ GRCEC
Sbjct: 340 DCGK--PTC--PHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECD 395
Query: 383 PEFQPPDCSS--CAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
F DC C G + C C C+ G GE C+ CP + G+ E
Sbjct: 396 DGFTGADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLR--CPNDCHSRGRCVEG 452
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK 495
+CE G+ +C + C C + G C C Y+G C Q
Sbjct: 453 KCVCEQGFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRDRQC--------- 501
Query: 496 PCNCDTSGTEPSICDDVSGQCICKAGFGGPRC------------DQCLSGYYMQVLG-RE 542
P +C G +C V GQC+C+ GF GP C +C++G + G
Sbjct: 502 PRDCSNRG----LC--VDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMG 555
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLS--CNCDVS 598
+ C C P+ DG+C C F G C Q C C+S C C+
Sbjct: 556 KDCKEQRC-PSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICN-E 613
Query: 599 GSIGSTCDD 607
G G C +
Sbjct: 614 GYSGEDCSE 622
Score = 63.3 bits (147), Expect = 2e-08
Identities = 93/350 (26%), Positives = 122/350 (34%), Gaps = 68/350 (19%)
Query: 470 CTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C+ + +S C C+ G+ P C C + C D GQCIC GF G C
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKG-PNCSEPECPGNCHLRGRCID--GQCICDDGFTGEDCS 217
Query: 529 Q------------CLSGYYMQVLG-RERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
Q C++G + G C C S DG C C F G
Sbjct: 218 QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGD 277
Query: 576 QCDQ--CSPGYYKYPDCL--SCNCDVSGSIGSTCDD--------------NGLCHCKSNF 617
C++ C Y C+ C CD G G C + NG C+C+ F
Sbjct: 278 DCNKPLCLNNCYNRGRCVENECVCD-EGFTGEDCSELICPNDCFDRGRCINGTCYCEEGF 336
Query: 618 DGAKC--DTCREQFYNYPACEE--CNCDP--RGVTASFAGCGSVPAGELCQCKDR-VQGR 670
G C TC + CEE C CD GV S C PA C + R V GR
Sbjct: 337 TGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC---PAD--CHNRGRCVDGR 391
Query: 671 I-CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-- 727
C+D + C + C + G C +GQCVC + C Q
Sbjct: 392 CECDD---------GFTGADCGELKC--PNGCSGHGRC--VNGQCVCDEGYTGEDCSQLR 438
Query: 728 CLDGFYRLQTNDVFGCTECDCDIG-GSIDNNCDKTTGQCHCHSRVEGRRC 776
C + + + V G +C C+ G D + CH H R C
Sbjct: 439 CPNDCHS-RGRCVEG--KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMC 485
Score = 58.4 bits (135), Expect = 5e-07
Identities = 103/398 (25%), Positives = 133/398 (33%), Gaps = 93/398 (23%)
Query: 1736 CQCPRAYRGLSCEQ------CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNT- 1788
C C Y G C + C+E H G CV C D C N +CLN N
Sbjct: 236 CICFEGYAGADCSREICPVPCSEEHGTCVDGLCV-CHDGFAGDDC--NKPLCLNNCYNRG 292
Query: 1789 --IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-----SCD 1831
+ + C C G+ G+ + + P DC C C + + +C
Sbjct: 293 RCVENEC-VCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH 351
Query: 1832 LSENGSLISCNCQPGYGGARC--EYCAAGYY-------GIPEDTDLHTGDYCKPCNCSGN 1882
C C G+ G C + C A + G E D TG C C
Sbjct: 352 TQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG 411
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCTA--CICDE-FGMA 1938
+ G C +NG C+ C G C+ L P D C C+C++ F
Sbjct: 412 CSGH--GRC--VNGQCV-CDEGYTGEDCSQLRCPN---DCHSRGRCVEGKCVCEQGFKGY 463
Query: 1939 DCDSTT-------------GTCVCRPGVIGEKC-DRCAPDHWGLNTGL----------GC 1974
DC + G CVC G GE C DR P N GL G
Sbjct: 464 DCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCS-NRGLCVDGQCVCEDGF 522
Query: 1975 TPCNCGIASESTQCDDD----NGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNT 2028
T +C S C NGQC C +G GK C +C + + C C+
Sbjct: 523 TGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHE 582
Query: 2029 GY--------SVGFMCNATGQCE-----CLPGVIGEKC 2053
G+ S CN GQC C G GE C
Sbjct: 583 GFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDC 620
Score = 57.6 bits (133), Expect = 8e-07
Identities = 94/358 (26%), Positives = 127/358 (35%), Gaps = 65/358 (18%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQC---NGHSDQCDVNTGICLNCADN--TI 1789
C C ++G +C E G+ L G C+ QC +G + + +C D +
Sbjct: 174 CVCEPGWKGPNCSEPECPGNCHL-RGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCV 232
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS--CNCQPGY 1847
C C GY G DC CP+P C E+G+ + C C G+
Sbjct: 233 NGVC-ICFEGYAG-------ADCSREICPVP---------CS-EEHGTCVDGLCVCHDGF 274
Query: 1848 GGARCE--YCAAGYY--GIPEDTDLHTGDYCKPCNCSGNINPQD---PGSCDSINGDCLK 1900
G C C Y G + + + +CS I P D G C ING C
Sbjct: 275 AGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCY- 331
Query: 1901 CVNNTAGAACN--LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
C G C C + + C+CDE G A D + C G
Sbjct: 332 CEEGFTGEDCGKPTCPHACHTQGRCEEG--QCVCDE-GFAGVDCSEKRCPADCHNRGRCV 388
Query: 1959 D-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
D RC D G C G + +C NGQC C +G TG+ C Q ++
Sbjct: 389 DGRCECDDGFTGADCGELKCPNGCSGHG-RCV--NGQCVCDEGYTGEDCSQLRCPNDCHS 445
Query: 2018 KDGC--DHCNCNTGYSVGFMCN--------------ATGQCECLPGVIGEKC-DR-CP 2057
+ C C C G+ G+ C+ G C C G GE C DR CP
Sbjct: 446 RGRCVEGKCVCEQGFK-GYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCP 502
Score = 50.0 bits (114), Expect = 2e-04
Identities = 69/275 (25%), Positives = 105/275 (38%), Gaps = 55/275 (20%)
Query: 1735 ECQCPRAYRGLSCEQ--C-AEGHYRLPSGFCVP--CQCNGHSDQCDVNTGICLN-CADN- 1787
+C C + G+ C + C A+ H R G CV C+C+ D C N C+ +
Sbjct: 360 QCVCDEGFAGVDCSEKRCPADCHNR---GRCVDGRCECDDGFTGADCGELKCPNGCSGHG 416
Query: 1788 -TIGDHCEFCMSGYHGD--ATVGTPRDCLI--------CACPMPYPSNNFA-LSC--DLS 1833
+ C C GY G+ + + P DC C C + + + +SC D
Sbjct: 417 RCVNGQC-VCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCH 475
Query: 1834 ENGSLIS--CNCQPGYGGARCE--YCA--AGYYGIPED-----TDLHTGDYCKPCNCSGN 1882
++G ++ C C GY G C C G+ D D TG C +C +
Sbjct: 476 QHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND 535
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDA-------IFSKNCTACICD 1933
+ Q G C +NG C+ C G C C +G I + T C
Sbjct: 536 CHGQ--GRC--VNGQCV-CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590
Query: 1934 EFGM-ADCDS----TTGTCVCRPGVIGEKCDRCAP 1963
+ +DC++ +G C+C G GE C +P
Sbjct: 591 QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSP 625
Score = 48.4 bits (110), Expect = 5e-04
Identities = 56/200 (28%), Positives = 77/200 (38%), Gaps = 31/200 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G T +C+ +CP + GR C G+ G+ +C CP+
Sbjct: 423 CVCD-EGYTGEDCSQL--RCPNDCHSRGRCVEGKCVCEQGFKGY-DCSDMSCPNDCHQHG 478
Query: 1397 ---NGMCICPKNVEGENC-DR-----CKPYTFNFDVQRGCDD----CNCNPLGVVGN-QL 1442
NGMC+C GE+C DR C D Q C+D +C L +
Sbjct: 479 RCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHG 538
Query: 1443 QCEADSGKCACRENVRGRVC--DHCVPGHYAFPDCY--QCTCNRHGTTYDVCDQNTAQCY 1498
Q +G+C C E G+ C C + C QC C+ T D C Q++
Sbjct: 539 QGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLD-CGQHSCPSD 597
Query: 1499 CKTNVRGQACD---TCKEEY 1515
C N GQ C E Y
Sbjct: 598 C--NNLGQCVSGRCICNEGY 615
Score = 41.9 bits (94), Expect = 0.042
Identities = 60/220 (27%), Positives = 83/220 (37%), Gaps = 32/220 (14%)
Query: 1305 EQC-ASYNYYISPNETGLCREAMFSITSEYNSGARPCLCD--FMGS--TELECNTFGGQC 1359
EQC A + P L S +++ C+C+ + G +E EC G C
Sbjct: 138 EQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECP---GNC 194
Query: 1360 PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDRC 1414
+ I C C G+ G +C CPS C+D NG+CIC + G +C R
Sbjct: 195 HLRGRCIDGQC-ICDDGFTG-EDCSQLACPSD--CNDQGKCVNGVCICFEGYAGADCSRE 250
Query: 1415 KPYTFNFDVQRGCDD--CNCNPLGVVGNQLQCEADSGKCACRENV--RGR-VCDHCVPGH 1469
+ C D C C+ G G+ D K C N RGR V + CV
Sbjct: 251 ICPVPCSEEHGTCVDGLCVCHD-GFAGD------DCNKPLCLNNCYNRGRCVENECVCDE 303
Query: 1470 -YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ DC + C C T CYC+ G+ C
Sbjct: 304 GFTGEDCSELICPNDCFDRGRCINGT--CYCEEGFTGEDC 341
Score = 41.1 bits (92), Expect = 0.073
Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 29/149 (19%)
Query: 1340 CLCDFMGSTELECNTFGGQCP--CKPN--VIGRTCSACRTGYYGFPNCRPCHCPSTAICD 1395
C+CD G T +C QCP C + C C G+ G P+C CP+
Sbjct: 485 CVCDD-GYTGEDCRD--RQCPRDCSNRGLCVDGQC-VCEDGFTG-PDCAELSCPNDCHGQ 539
Query: 1396 D---NGMCICPKNVEGENC--DRCKPYTFNFDVQRGCDD--CNCNP--LGVVGNQLQCEA 1446
NG C+C + G++C RC Q C D C C+ G+ Q C +
Sbjct: 540 GRCVNGQCVCHEGFMGKDCKEQRCPSDCHG---QGRCVDGQCICHEGFTGLDCGQHSCPS 596
Query: 1447 D--------SGKCACRENVRGRVCDHCVP 1467
D SG+C C E G C P
Sbjct: 597 DCNNLGQCVSGRCICNEGYSGEDCSEVSP 625
Score = 39.1 bits (87), Expect = 0.30
Identities = 60/237 (25%), Positives = 85/237 (35%), Gaps = 36/237 (15%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD 607
C TG T G+ N T G C C PG+ K P+C C + + C D
Sbjct: 147 CLQPATGRLDTRPFCSGRGNFSTE--GCGC-VCEPGW-KGPNCSEPECPGNCHLRGRCID 202
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAG-CGSVPAGELCQCKDR 666
G C C F G C Q C + GV F G G+ + E+C
Sbjct: 203 -GQCICDDGFTGEDCS----QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCS 257
Query: 667 VQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
+ C D + ++ F + CN L L C + G+CV E +C
Sbjct: 258 EEHGTCVDGLCVC-----HDGFAGDDCNKPLC-----LNNCYNR-GRCV------ENEC- 299
Query: 727 QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
C +GF +++ +C D G I+ G C+C G C +P H
Sbjct: 300 VCDEGFTGEDCSELICPNDC-FDRGRCIN-------GTCYCEEGFTGEDCGKPTCPH 348
Score = 37.9 bits (84), Expect = 0.68
Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDR-CKPYTFNFDVQRG 1426
C G+ G +C CP+ C D NG C C + GE+C + P+ + Q
Sbjct: 301 CDEGFTG-EDCSELICPND--CFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH--TQGR 355
Query: 1427 CDD--CNCNP--LGVVGNQLQCEAD--------SGKCACRENVRGRVCDH--CVPGHYAF 1472
C++ C C+ GV ++ +C AD G+C C + G C C G
Sbjct: 356 CEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGH 415
Query: 1473 PDCY--QCTCNRHGTTYDVCDQ 1492
C QC C+ G T + C Q
Sbjct: 416 GRCVNGQCVCD-EGYTGEDCSQ 436
Score = 37.5 bits (83), Expect = 0.90
Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 18/177 (10%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G ++C+ +CP + GR C G+ G +C CP+
Sbjct: 361 CVCD-EGFAGVDCSE--KRCPADCHNRGRCVDGRCECDDGFTG-ADCGELKCPNGCSGHG 416
Query: 1397 ---NGMCICPKNVEGENCDRCK-PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
NG C+C + GE+C + + P + + C C G G C S
Sbjct: 417 RCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQ-GFKG--YDCSDMSCPND 473
Query: 1453 CRENVRGRVCDHCV-PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C ++ R V CV Y DC C R + +C QC C+ G C
Sbjct: 474 CHQHGR-CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD--GQCVCEDGFTGPDC 527
>AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein
protein.
Length = 2233
Score = 94.3 bits (224), Expect = 7e-18
Identities = 123/472 (26%), Positives = 174/472 (36%), Gaps = 77/472 (16%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNC--KPCTCNLNGTEGEHCTPTDGLC 425
GN E C C P ++ P+CS C C C C+ +G GE C+ C
Sbjct: 197 GNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICD-DGFTGEDCSQL--AC 253
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSY-VCDKLTGDCTCKSKYSGRTC 481
P N GK IC +GY +C C S + C + G C C ++G C
Sbjct: 254 PSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTC--VDGLCVCHDGFAGDDC 311
Query: 482 NQ--CQAGYYNYPTC--KPCNCDTSGTE--------PSICDD----VSGQCICKAGFGGP 525
N+ C YN C C CD T P+ C D ++G C C+ GF G
Sbjct: 312 NKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGE 371
Query: 526 RCDQ--CLSGYYMQVLGRERQCV------PCNCD----PTGSTSTSCSADGKCNCLTNFG 573
C + C + Q E QCV +C P + DG+C C F
Sbjct: 372 DCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFT 431
Query: 574 GAQCDQ--CSPGYYKYPDCLS--CNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCR 626
GA C + C G + C++ C CD G G C CH + KC C
Sbjct: 432 GADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLRCPNDCHSRGRCVEGKC-VCE 489
Query: 627 EQFYNYPACE-EC--NCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICND---CKPLY 679
+ F Y + C +C G C GE C+DR R C++ C
Sbjct: 490 QGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGE--DCRDRQCPRDCSNRGLCVDGQ 547
Query: 680 WNLQE-YNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG----ERQCDQCLDGFY 733
++ + C + +C + G C +GQCVC + +G E++C G
Sbjct: 548 CVCEDGFTGPDCAELSC--PNDCHGRGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQG 603
Query: 734 RLQTNDVF---GCTECDCDIGGSIDNNCDK----TTGQCHCHSRVEGRRCDQ 778
R G T DC S ++C+ +G+C C+ G C +
Sbjct: 604 RCVDGQCICHEGFTGLDCG-QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 654
Score = 80.2 bits (189), Expect = 1e-13
Identities = 110/429 (25%), Positives = 157/429 (36%), Gaps = 86/429 (20%)
Query: 227 IGGRCMC-NGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
+ G C+C G+A AD + + + C +H TC C GF + ++
Sbjct: 264 VNGVCICFEGYAG----ADCSREICPVPCSEEHGTCVDGLCVCHDGFA------GDDCNK 313
Query: 286 FSCEPCNCHNH----TTECTYDPEIDEKRLSLDI--NGRYEGGGKCLN----CQHNTEGI 335
C NC+N EC D + S I N ++ G +C+N C+ G
Sbjct: 314 PLCLN-NCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRG-RCINGTCYCEEGFTGE 371
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE-------------SGRCECR 382
+C K PT P+ C CD F+ +C E+ GRCEC
Sbjct: 372 DCGK--PTC--PHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECD 427
Query: 383 PEFQPPDCSS--CAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
F DC C G + C C C+ G GE C+ CP + G+ E
Sbjct: 428 DGFTGADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLR--CPNDCHSRGRCVEG 484
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK 495
+CE G+ +C + C C + G C C Y+G C Q
Sbjct: 485 KCVCEQGFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRDRQC--------- 533
Query: 496 PCNCDTSGTEPSICDDVSGQCICKAGFGGPRC------------DQCLSGYYMQVLG-RE 542
P +C G +C V GQC+C+ GF GP C +C++G + G
Sbjct: 534 PRDCSNRG----LC--VDGQCVCEDGFTGPDCAELSCPNDCHGRGRCVNGQCVCHEGFMG 587
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLS--CNCDVS 598
+ C C P+ DG+C C F G C Q C C+S C C+
Sbjct: 588 KDCKEQRC-PSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICN-E 645
Query: 599 GSIGSTCDD 607
G G C +
Sbjct: 646 GYSGEDCSE 654
Score = 63.3 bits (147), Expect = 2e-08
Identities = 93/350 (26%), Positives = 122/350 (34%), Gaps = 68/350 (19%)
Query: 470 CTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C+ + +S C C+ G+ P C C + C D GQCIC GF G C
Sbjct: 193 CSGRGNFSTEGCGCVCEPGWKG-PNCSEPECPGNCHLRGRCID--GQCICDDGFTGEDCS 249
Query: 529 Q------------CLSGYYMQVLG-RERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
Q C++G + G C C S DG C C F G
Sbjct: 250 QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGD 309
Query: 576 QCDQ--CSPGYYKYPDCL--SCNCDVSGSIGSTCDD--------------NGLCHCKSNF 617
C++ C Y C+ C CD G G C + NG C+C+ F
Sbjct: 310 DCNKPLCLNNCYNRGRCVENECVCD-EGFTGEDCSELICPNDCFDRGRCINGTCYCEEGF 368
Query: 618 DGAKC--DTCREQFYNYPACEE--CNCDP--RGVTASFAGCGSVPAGELCQCKDR-VQGR 670
G C TC + CEE C CD GV S C PA C + R V GR
Sbjct: 369 TGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC---PAD--CHNRGRCVDGR 423
Query: 671 I-CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-- 727
C+D + C + C + G C +GQCVC + C Q
Sbjct: 424 CECDD---------GFTGADCGELKC--PNGCSGHGRC--VNGQCVCDEGYTGEDCSQLR 470
Query: 728 CLDGFYRLQTNDVFGCTECDCDIG-GSIDNNCDKTTGQCHCHSRVEGRRC 776
C + + + V G +C C+ G D + CH H R C
Sbjct: 471 CPNDCHS-RGRCVEG--KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMC 517
Score = 58.4 bits (135), Expect = 5e-07
Identities = 103/398 (25%), Positives = 133/398 (33%), Gaps = 93/398 (23%)
Query: 1736 CQCPRAYRGLSCEQ------CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNT- 1788
C C Y G C + C+E H G CV C D C N +CLN N
Sbjct: 268 CICFEGYAGADCSREICPVPCSEEHGTCVDGLCV-CHDGFAGDDC--NKPLCLNNCYNRG 324
Query: 1789 --IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-----SCD 1831
+ + C C G+ G+ + + P DC C C + + +C
Sbjct: 325 RCVENEC-VCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH 383
Query: 1832 LSENGSLISCNCQPGYGGARC--EYCAAGYY-------GIPEDTDLHTGDYCKPCNCSGN 1882
C C G+ G C + C A + G E D TG C C
Sbjct: 384 TQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG 443
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN-LCAPGFYGDAIFSKNCTA--CICDE-FGMA 1938
+ G C +NG C+ C G C+ L P D C C+C++ F
Sbjct: 444 CSGH--GRC--VNGQCV-CDEGYTGEDCSQLRCPN---DCHSRGRCVEGKCVCEQGFKGY 495
Query: 1939 DCDSTT-------------GTCVCRPGVIGEKC-DRCAPDHWGLNTGL---GCTPCNCGI 1981
DC + G CVC G GE C DR P N GL G C G
Sbjct: 496 DCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCS-NRGLCVDGQCVCEDGF 554
Query: 1982 ASEST---QCDDD--------NGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNT 2028
C +D NGQC C +G GK C +C + + C C+
Sbjct: 555 TGPDCAELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHE 614
Query: 2029 GY--------SVGFMCNATGQCE-----CLPGVIGEKC 2053
G+ S CN GQC C G GE C
Sbjct: 615 GFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDC 652
Score = 57.6 bits (133), Expect = 8e-07
Identities = 94/358 (26%), Positives = 127/358 (35%), Gaps = 65/358 (18%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQC---NGHSDQCDVNTGICLNCADN--TI 1789
C C ++G +C E G+ L G C+ QC +G + + +C D +
Sbjct: 206 CVCEPGWKGPNCSEPECPGNCHL-RGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCV 264
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS--CNCQPGY 1847
C C GY G DC CP+P C E+G+ + C C G+
Sbjct: 265 NGVC-ICFEGYAG-------ADCSREICPVP---------CS-EEHGTCVDGLCVCHDGF 306
Query: 1848 GGARCE--YCAAGYY--GIPEDTDLHTGDYCKPCNCSGNINPQD---PGSCDSINGDCLK 1900
G C C Y G + + + +CS I P D G C ING C
Sbjct: 307 AGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCY- 363
Query: 1901 CVNNTAGAACN--LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
C G C C + + C+CDE G A D + C G
Sbjct: 364 CEEGFTGEDCGKPTCPHACHTQGRCEEG--QCVCDE-GFAGVDCSEKRCPADCHNRGRCV 420
Query: 1959 D-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
D RC D G C G + +C NGQC C +G TG+ C Q ++
Sbjct: 421 DGRCECDDGFTGADCGELKCPNGCSGHG-RCV--NGQCVCDEGYTGEDCSQLRCPNDCHS 477
Query: 2018 KDGC--DHCNCNTGYSVGFMCN--------------ATGQCECLPGVIGEKC-DR-CP 2057
+ C C C G+ G+ C+ G C C G GE C DR CP
Sbjct: 478 RGRCVEGKCVCEQGFK-GYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCP 534
Score = 48.4 bits (110), Expect = 5e-04
Identities = 68/275 (24%), Positives = 105/275 (38%), Gaps = 55/275 (20%)
Query: 1735 ECQCPRAYRGLSCEQ--C-AEGHYRLPSGFCVP--CQCNGHSDQCDVNTGICLN-CADN- 1787
+C C + G+ C + C A+ H R G CV C+C+ D C N C+ +
Sbjct: 392 QCVCDEGFAGVDCSEKRCPADCHNR---GRCVDGRCECDDGFTGADCGELKCPNGCSGHG 448
Query: 1788 -TIGDHCEFCMSGYHGD--ATVGTPRDCLI--------CACPMPYPSNNFA-LSC--DLS 1833
+ C C GY G+ + + P DC C C + + + +SC D
Sbjct: 449 RCVNGQC-VCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCH 507
Query: 1834 ENGSLIS--CNCQPGYGGARCE--YCA--AGYYGIPED-----TDLHTGDYCKPCNCSGN 1882
++G ++ C C GY G C C G+ D D TG C +C +
Sbjct: 508 QHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND 567
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDA-------IFSKNCTACICD 1933
+ + G C +NG C+ C G C C +G I + T C
Sbjct: 568 CHGR--GRC--VNGQCV-CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 622
Query: 1934 EFGM-ADCDS----TTGTCVCRPGVIGEKCDRCAP 1963
+ +DC++ +G C+C G GE C +P
Sbjct: 623 QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSP 657
Score = 48.0 bits (109), Expect = 6e-04
Identities = 60/204 (29%), Positives = 80/204 (39%), Gaps = 39/204 (19%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G T +C+ +CP + GR C G+ G+ +C CP+
Sbjct: 455 CVCD-EGYTGEDCSQL--RCPNDCHSRGRCVEGKCVCEQGFKGY-DCSDMSCPNDCHQHG 510
Query: 1397 ---NGMCICPKNVEGENC-DRCKPYTFNFDVQRG-CDD--CNCNPLGVVG---NQLQCEA 1446
NGMC+C GE+C DR P + RG C D C C G G +L C
Sbjct: 511 RCVNGMCVCDDGYTGEDCRDRQCPRDCS---NRGLCVDGQCVCED-GFTGPDCAELSCPN 566
Query: 1447 D--------SGKCACRENVRGRVC--DHCVPGHYAFPDCY--QCTCNRHGTTYDVCDQNT 1494
D +G+C C E G+ C C + C QC C+ T D C Q++
Sbjct: 567 DCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLD-CGQHS 625
Query: 1495 AQCYCKTNVRGQACD---TCKEEY 1515
C N GQ C E Y
Sbjct: 626 CPSDC--NNLGQCVSGRCICNEGY 647
Score = 41.9 bits (94), Expect = 0.042
Identities = 60/220 (27%), Positives = 83/220 (37%), Gaps = 32/220 (14%)
Query: 1305 EQC-ASYNYYISPNETGLCREAMFSITSEYNSGARPCLCD--FMGS--TELECNTFGGQC 1359
EQC A + P L S +++ C+C+ + G +E EC G C
Sbjct: 170 EQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECP---GNC 226
Query: 1360 PCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDRC 1414
+ I C C G+ G +C CPS C+D NG+CIC + G +C R
Sbjct: 227 HLRGRCIDGQC-ICDDGFTG-EDCSQLACPSD--CNDQGKCVNGVCICFEGYAGADCSRE 282
Query: 1415 KPYTFNFDVQRGCDD--CNCNPLGVVGNQLQCEADSGKCACRENV--RGR-VCDHCVPGH 1469
+ C D C C+ G G+ D K C N RGR V + CV
Sbjct: 283 ICPVPCSEEHGTCVDGLCVCHD-GFAGD------DCNKPLCLNNCYNRGRCVENECVCDE 335
Query: 1470 -YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ DC + C C T CYC+ G+ C
Sbjct: 336 GFTGEDCSELICPNDCFDRGRCINGT--CYCEEGFTGEDC 373
Score = 40.3 bits (90), Expect = 0.13
Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 29/149 (19%)
Query: 1340 CLCDFMGSTELECNTFGGQCP--CKPN--VIGRTCSACRTGYYGFPNCRPCHCPSTAICD 1395
C+CD G T +C QCP C + C C G+ G P+C CP+
Sbjct: 517 CVCDD-GYTGEDCRD--RQCPRDCSNRGLCVDGQC-VCEDGFTG-PDCAELSCPNDCHGR 571
Query: 1396 D---NGMCICPKNVEGENC--DRCKPYTFNFDVQRGCDD--CNCNP--LGVVGNQLQCEA 1446
NG C+C + G++C RC Q C D C C+ G+ Q C +
Sbjct: 572 GRCVNGQCVCHEGFMGKDCKEQRCPSDCHG---QGRCVDGQCICHEGFTGLDCGQHSCPS 628
Query: 1447 D--------SGKCACRENVRGRVCDHCVP 1467
D SG+C C E G C P
Sbjct: 629 DCNNLGQCVSGRCICNEGYSGEDCSEVSP 657
Score = 39.1 bits (87), Expect = 0.30
Identities = 60/237 (25%), Positives = 85/237 (35%), Gaps = 36/237 (15%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD 607
C TG T G+ N T G C C PG+ K P+C C + + C D
Sbjct: 179 CLQPATGRLDTRPFCSGRGNFSTE--GCGC-VCEPGW-KGPNCSEPECPGNCHLRGRCID 234
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAG-CGSVPAGELCQCKDR 666
G C C F G C Q C + GV F G G+ + E+C
Sbjct: 235 -GQCICDDGFTGEDCS----QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCS 289
Query: 667 VQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD 726
+ C D + ++ F + CN L L C + G+CV E +C
Sbjct: 290 EEHGTCVDGLCVC-----HDGFAGDDCNKPLC-----LNNCYNR-GRCV------ENEC- 331
Query: 727 QCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
C +GF +++ +C D G I+ G C+C G C +P H
Sbjct: 332 VCDEGFTGEDCSELICPNDC-FDRGRCIN-------GTCYCEEGFTGEDCGKPTCPH 380
Score = 37.9 bits (84), Expect = 0.68
Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDR-CKPYTFNFDVQRG 1426
C G+ G +C CP+ C D NG C C + GE+C + P+ + Q
Sbjct: 333 CDEGFTG-EDCSELICPND--CFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH--TQGR 387
Query: 1427 CDD--CNCNP--LGVVGNQLQCEAD--------SGKCACRENVRGRVCDH--CVPGHYAF 1472
C++ C C+ GV ++ +C AD G+C C + G C C G
Sbjct: 388 CEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGH 447
Query: 1473 PDCY--QCTCNRHGTTYDVCDQ 1492
C QC C+ G T + C Q
Sbjct: 448 GRCVNGQCVCD-EGYTGEDCSQ 468
Score = 37.5 bits (83), Expect = 0.90
Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 18/177 (10%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G ++C+ +CP + GR C G+ G +C CP+
Sbjct: 393 CVCD-EGFAGVDCSE--KRCPADCHNRGRCVDGRCECDDGFTG-ADCGELKCPNGCSGHG 448
Query: 1397 ---NGMCICPKNVEGENCDRCK-PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
NG C+C + GE+C + + P + + C C G G C S
Sbjct: 449 RCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQ-GFKG--YDCSDMSCPND 505
Query: 1453 CRENVRGRVCDHCV-PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C ++ R V CV Y DC C R + +C QC C+ G C
Sbjct: 506 CHQHGR-CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD--GQCVCEDGFTGPDC 559
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 93.9 bits (223), Expect = 1e-17
Identities = 155/638 (24%), Positives = 219/638 (34%), Gaps = 107/638 (16%)
Query: 211 DPTVTRRYFYSIKDISIGGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCN 266
DPT + + G C NG+ C+P N +I C+ N C G C
Sbjct: 710 DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCK 769
Query: 267 KCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCL 326
SG+ + + FS NC + EC +P +++ D+ G KC
Sbjct: 770 DMTSGY------VCTCREGFSGP--NCQTNINECASNPCLNQGTCIDDV-----AGYKC- 815
Query: 327 NCQHNTEGINCN----KCRPTYYRPYGK-RWDELDVCQPCQCDPHFSTGNCEEESGRCEC 381
NC G C C P+ R G+ R E C C + CE + C
Sbjct: 816 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVL 875
Query: 382 RPEFQPPDCSS--------CAYGYF------DYPNCKPCTCNLNGTEGEHCTP--TDGLC 425
P C + C GY D +C+P C+ G+ CT C
Sbjct: 876 SPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS----CTDGINTAFC 931
Query: 426 PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQ 485
C + G CE ED EC + C + + D T CTC + +SG C
Sbjct: 932 DCLPGFRGTFCE--ED---INECASDPCRNGANCTDCVDSYT--CTCPAGFSGIHCEN-- 982
Query: 486 AGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
N P C +C GT D ++ C+C GF G C ++ Q
Sbjct: 983 ----NTPDCTESSCFNGGT---CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGT 1035
Query: 545 CVP------CNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQ--------CSPGYYK-YP 588
C C C P G T +C + C+ G +C Q C G+ Y
Sbjct: 1036 CQDGCGSYRCTC-PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
Query: 589 DCLSCNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP- 642
D S +C+V+ + C GLC N +C Y +EC+ P
Sbjct: 1095 DVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPC 1154
Query: 643 -RGVTAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G T + + G C V C + + + + C+ L N + C C
Sbjct: 1155 QNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS-CPRGT 1213
Query: 698 AGTLNSLGA--CN------TKSGQC----VCKQHVGERQCDQCLDGFYRLQTN-DVFGCT 744
G + CN ++S +C C VG C C GF + DV C
Sbjct: 1214 QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT-CPPGFVGERCEGDVNECL 1272
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRV--EGRRCDQPI 780
CD G+ NC + HC R GRRC+ I
Sbjct: 1273 SNPCDARGT--QNCVQRVNDFHCECRAGHTGRRCESVI 1308
Score = 93.1 bits (221), Expect = 2e-17
Identities = 139/570 (24%), Positives = 188/570 (32%), Gaps = 112/570 (19%)
Query: 236 HADTCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWDRF--SCEP 290
H TC+ D N +C C T GP C C+ D + +CEP
Sbjct: 614 HGGTCQDRD-----NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEP 668
Query: 291 ----CNCHNHTTECTYDPEIDEKRLSLDING---RYEGGGKCLNCQHNTEGINCNKCRPT 343
C+ + EC +P + ING R G C N N C
Sbjct: 669 GYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC--- 725
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGY------ 397
+G D L+ + C CDP +S NC+ + CE P C GY
Sbjct: 726 ---VHGACRDSLNGYK-CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE 781
Query: 398 -FDYPNCK----PCTCNLNGTEGEHCTPTDGL-CPCKYNYAGKSCEICEDGYYSPECKNC 451
F PNC+ C N +G G C C Y G +CE+ +P C
Sbjct: 782 GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEV----VLAP-CAPS 836
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
C G D + C C + + G+TC N PC S C +
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEV----DINECVLSPCRHGAS------CQN 886
Query: 512 VSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
G +C C+AG+ G C+ + C P C GS + + C+CL
Sbjct: 887 THGGYRCHCQAGYSGRNCETDID-----------DCRPNPCHNGGSCTDGINT-AFCDCL 934
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
F G C++ +C S C +G+ + C D+ C C + F G C+
Sbjct: 935 PGFRGTFCEE------DINECASDPCR-NGANCTDCVDSYTCTCPAGFSGIHCEN----- 982
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
N P C E +C G G S C C G C +++
Sbjct: 983 -NTPDCTESSCFNGGTCVD--GINSF----TCLCPPGFTGSYC-----------QHDVNE 1024
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD 749
C+ C GT C S +C C Q C N V C C
Sbjct: 1025 CDSQPCLHGGTCQD--GCG--SYRCTCPQGYTGPNCQ-----------NLVHWCDSSPCK 1069
Query: 750 IGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
GG T +C C S G CD P
Sbjct: 1070 NGGKCWQT--HTQYRCECPSGWTGLYCDVP 1097
Score = 85.0 bits (201), Expect = 5e-15
Identities = 137/569 (24%), Positives = 198/569 (34%), Gaps = 98/569 (17%)
Query: 253 VCRCQHNTCGPQCNK----CCSGFE--QKKWRISQNWDRFSCEPCN------CHNHTTEC 300
+C C GP C++ C G + + F C+ C EC
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC 456
Query: 301 TYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINC----NKCRPTYYRPYGKRWDELD 356
+P LD G ++ C+ C EG++C ++C + G+ D+++
Sbjct: 457 VSNP-CQNDATCLDQIGEFQ----CI-CMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
Query: 357 VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGE 416
Q C+C F+ C+ + C P C D PN C C G G
Sbjct: 511 EFQ-CECPTGFTGHLCQYDVDECASTPCKNGAKC-------LDGPNTYTCVCT-EGYTGT 561
Query: 417 HCTPTDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCK 473
HC C PC Y C+DG + C C G + C+ +C+ +
Sbjct: 562 HCEVDIDECDPDPCHYGS-------CKDGVAT---FTCLCRP-GYTGHHCETNINECSSQ 610
Query: 474 SKYSGRTCNQCQAGYYNY-------PTCKPC--NCDTSGTEPSIC-DDVSG-QCICKAGF 522
G TC Y + P C+ +C +S + C D + G +C C+ G+
Sbjct: 611 PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGY 670
Query: 523 GGPRC----DQCLSGYYMQVLGRERQCV---PCNCDPTGSTSTSCSAD-GKCNCLTNFGG 574
G C D+C +G G + C C P G +C ++ +CN G
Sbjct: 671 TGSMCNINIDEC-AGNPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECNSNPCVHG 728
Query: 575 AQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPA 634
A C GY C+CD S G+ CD N C+SN TC++ Y
Sbjct: 729 A-CRDSLNGY-------KCDCDPGWS-GTNCDINNN-ECESN-PCVNGGTCKDMTSGYVC 777
Query: 635 -CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
C E P T + C S P C D V G CN P E C
Sbjct: 778 TCREGFSGPNCQT-NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPS 836
Query: 694 NCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS 753
C G + + +S CVC + C+ D+ C C G S
Sbjct: 837 PCRNGGECRQ--SEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGAS 883
Query: 754 IDNNCDKTTG--QCHCHSRVEGRRCDQPI 780
C T G +CHC + GR C+ I
Sbjct: 884 ----CQNTHGGYRCHCQAGYSGRNCETDI 908
Score = 82.2 bits (194), Expect = 3e-14
Identities = 123/502 (24%), Positives = 177/502 (35%), Gaps = 83/502 (16%)
Query: 321 GGGKCLNCQHNTEGINCNK----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES 376
G +C+ C+ G NC + C P+ + G DV C C P F+ NCEE
Sbjct: 200 GSYRCV-CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA--GK 434
C P + +C G Y NC+ C T G++CT C N G
Sbjct: 259 DDC---PGNNCKNGGACVDGVNTY-NCR---CPPEWT-GQYCTEDVDECQLMPNACQNGG 310
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY----N 490
+C GY NC C G C + DC + + G TC+ A +Y +
Sbjct: 311 TCHNTHGGY------NCVC-VNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 491 YPTCKPCNCDTS-----GTEPSICD--DVSGQ--CICKAGFGGPRC----DQCL------ 531
T C+ + + E S CD V+G+ C C +G+ GP C D+C
Sbjct: 364 GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPC 423
Query: 532 --SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSP 582
+G + LG E QC+ C D S C D CL G QC C P
Sbjct: 424 EHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND--ATCLDQIGEFQC-ICMP 480
Query: 583 GYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
GY + + C + S C NG C K N +C T +EC P
Sbjct: 481 GY----EGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTP 536
Query: 643 RGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
+ A C P C C + G C ++ E +P C +C G
Sbjct: 537 ---CKNGAKCLDGPNTYTCVCTEGYTGTHCE------VDIDECDPDPCHYGSCK-DGVAT 586
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGC--------TECDCDIGGSI 754
C C+ ++ E C G ++ + C C+ ++
Sbjct: 587 FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCA 646
Query: 755 DNNCDKTTGQCHCHSRVEGRRC 776
+ CD T C +++G C
Sbjct: 647 SSPCDSGT----CLDKIDGYEC 664
Score = 81.4 bits (192), Expect = 6e-14
Identities = 140/573 (24%), Positives = 192/573 (33%), Gaps = 90/573 (15%)
Query: 229 GRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCNKCCSGFEQKKWRISQNWD 284
G C+ +G+ CEP NI + C N C G C +GF R + +
Sbjct: 653 GTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF---TCRCPEGYH 709
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEK-RLSLDINGRYEGGGKCLNCQHNTEGINC----NK 339
+P C + EC +P + R SL+ G KC +C G NC N+
Sbjct: 710 ----DP-TCLSEVNECNSNPCVHGACRDSLN-------GYKC-DCDPGWSGTNCDINNNE 756
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFD 399
C G ++ C C FS NC+ C P C GY
Sbjct: 757 CESNPC-VNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY-- 813
Query: 400 YPNC-KPCTCNLNGTEGEHCTPT----DGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
NC P T C P+ G C +Y SC +C G+ + + CE +
Sbjct: 814 KCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSC-VCPTGW---QGQTCEVD 869
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG 514
V C +C++ + G C+ CQAGY + + C D P+ C +
Sbjct: 870 INECVLSPC---RHGASCQNTHGGYRCH-CQAGY----SGRNCETDIDDCRPNPCHNGGS 921
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNF 572
C G CD CL G+ E C DP G+ T C C C F
Sbjct: 922 ---CTDGINTAFCD-CLPGFRGTFC--EEDINECASDPCRNGANCTDCVDSYTCTCPAGF 975
Query: 573 GGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCREQF 629
G C+ PDC +C G TC D + C C F G+ C
Sbjct: 976 SGIHCEN------NTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQ------ 1019
Query: 630 YNYPACEECNCDPRGVTASFAGCGS----VPAGEL-CQCKDRVQGRICNDCKPLYWNLQE 684
++ C+ C G GCGS P G C++ V + CK Q
Sbjct: 1020 HDVNECDSQPCLHGGTCQD--GCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQT 1077
Query: 685 YNPFGCEQCNCNLAGTLNSLGACNTKSGQC-VCKQHVGERQCDQCLDGFYRLQTNDVFGC 743
+ + CE C G C+ S C V Q G C G + + C
Sbjct: 1078 HTQYRCE-CPSGWTGLY-----CDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHC 1131
Query: 744 TECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C GS C+ +C G C
Sbjct: 1132 -RCQAGYTGSY---CEDLVDECSPSPCQNGATC 1160
Score = 79.8 bits (188), Expect = 2e-13
Identities = 137/562 (24%), Positives = 191/562 (33%), Gaps = 109/562 (19%)
Query: 228 GGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
GG C C + TC N LV C + C KC Q + W
Sbjct: 1033 GGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPC-KNGGKCWQTHTQYRCECPSGWTG 1091
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
C+ + C E+ +R +D+ + GG C++ NT +C +C+ Y
Sbjct: 1092 LYCDV-----PSVSC----EVAAQRQGVDVARLCQHGGLCVDAG-NTH--HC-RCQAGYT 1138
Query: 346 RPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSS---------CA 394
Y + D +D C P C + C + G C+C + +CS C
Sbjct: 1139 GSYCE--DLVDECSPSPCQ---NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ 1193
Query: 395 YG--YFDYPNCKPCTCNLNGTEGEHCT--------PTDGL-----C----PCKYNYAGKS 435
G D PN C+C GT+G HC P D + C C G S
Sbjct: 1194 NGGTCLDLPNTYKCSCP-RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYS 1252
Query: 436 CEICEDGYYSPECKN----C---ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C C G+ C+ C C+ G+ + V C C++ ++GR C G
Sbjct: 1253 CT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVING- 1310
Query: 489 YNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
CK C GT + G C C AGF G C+ R C
Sbjct: 1311 -----CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN-----------DARTCGS 1354
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN-CDVSGSIGSTCD 606
C G T S C CL F G +C + CL N C G+ T +
Sbjct: 1355 LRC-LNGGTCISGPRSPTCLCLGPFTGPECQ-----FPASSPCLGGNPCYNQGTCEPTSE 1408
Query: 607 DNGL-CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV--TASFAGCGSVPAGELC-- 661
C C + F+G C Y++ + P + C ++C
Sbjct: 1409 SPFYRCLCPAKFNGLLCHILD---YSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 1465
Query: 662 QCKDRVQGRICNDCKPLY---W-----NLQEYNPFGCEQCN--CNLAGTLNSLGACNTKS 711
QC + G DC + W +LQ + F C+ CN AG L C
Sbjct: 1466 QCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAE 1525
Query: 712 GQC------VCKQHVGERQCDQ 727
GQC CK H + CDQ
Sbjct: 1526 GQCNPLYDQYCKDHFSDGHCDQ 1547
Score = 74.9 bits (176), Expect = 5e-12
Identities = 102/376 (27%), Positives = 133/376 (35%), Gaps = 47/376 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC+ G +C+ G+ GF P C + ++C N CLN C D+ G
Sbjct: 756 ECESNPCVNGGTCKDMTSGYVCTCREGFSGP-NCQTNINECASNP--CLNQGTCIDDVAG 812
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ Y G AT + ++ C P P N C SE+ SC C G+ G
Sbjct: 813 YKCN-CLLPYTG-ATC----EVVLAPCA-PSPCRNGG-ECRQSEDYESFSCVCPTGWQGQ 864
Query: 1851 RCEY----CAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
CE C G Y C NC +I+ P C + G C
Sbjct: 865 TCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN-GGSCT 923
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF-GMADCDSTTG--TCVCRPGVIGE 1956
+N A C+ C PGF G ++ C D A+C TC C G G
Sbjct: 924 DGINT---AFCD-CLPGFRG-TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGI 978
Query: 1957 KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
C+ PD + G T C GI S + C C V +CD
Sbjct: 979 HCENNTPDCTESSCFNGGT-CVDGINSFTCLCPPGFTGSYCQHDVN--ECDSQPCLHGGT 1035
Query: 2017 TKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+DGC C C GY+ N C+ P G KC W Q C EC S
Sbjct: 1036 CQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC------WQTHTQYRC-ECPSG 1088
Query: 2075 TDALIFSVEDLSALLA 2090
L V +S +A
Sbjct: 1089 WTGLYCDVPSVSCEVA 1104
Score = 72.1 bits (169), Expect = 3e-11
Identities = 82/333 (24%), Positives = 117/333 (35%), Gaps = 42/333 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C+CP + G C+ Y + PC+ NG NT C+ C + G HCE
Sbjct: 513 QCECPTGFTGHLCQ------YDVDECASTPCK-NGAKCLDGPNTYTCV-CTEGYTGTHCE 564
Query: 1795 FCMSGYHGDAT-VGTPRD---CLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
+ D G+ +D C C Y ++ C+ + N C+ QP G
Sbjct: 565 VDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHH----CETNIN----ECSSQPCRHGG 616
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C+ Y TG NC N++ CDS G CL ++ G C
Sbjct: 617 TCQDRDNAYLCFCLKGT--TGP-----NCEINLDDCASSPCDS--GTCLDKID---GYEC 664
Query: 1911 NLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC----DRCAPD 1964
C PG+ G I C C G + TC C G C + C +
Sbjct: 665 -ACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSN 723
Query: 1965 ---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
H L C+C T CD +N +C V G C +G+ ++G
Sbjct: 724 PCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF 783
Query: 2022 DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
NC T + Q C+ V G KC+
Sbjct: 784 SGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
Score = 68.9 bits (161), Expect = 3e-10
Identities = 117/475 (24%), Positives = 167/475 (35%), Gaps = 83/475 (17%)
Query: 254 CRCQHNTCGPQC----NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
CRCQ G C ++C Q + +SC+ C H C+ EIDE
Sbjct: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCK-CVAGYHGVNCS--EEIDEC 1187
Query: 310 RLSLDINGRYEGGGKCLN--------CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
++ + GG CL+ C T+G++C P D + C
Sbjct: 1188 -----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV----DPVSRSPKC 1238
Query: 362 QCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
F+ G C ++ G C C P F C D C C+ GT+
Sbjct: 1239 -----FNNGTCVDQVGGYSCTCPPGFVGERCEG------DVNECLSNPCDARGTQNCVQR 1287
Query: 420 PTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG-DCTCKSKYSG 478
D C C+ + G+ CE +G CK C G+ + + G C C + + G
Sbjct: 1288 VNDFHCECRAGHTGRRCESVING-----CKGKPCKNGGTCAVASNTARGFICKCPAGFEG 1342
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQV 538
TC + TC C GT I S C+C F GP C S
Sbjct: 1343 ATCEN------DARTCGSLRCLNGGT--CISGPRSPTCLCLGPFTGPECQFPASS---PC 1391
Query: 539 LGRERQCVPCNCDPTG-STSTSCSADGKCNCLT------NF-GGAQCDQCSPGYYKYPDC 590
LG C+PT S C K N L +F GGA D P + +
Sbjct: 1392 LGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACEL 1451
Query: 591 LSCNCDVSGSIGSTCDDNGLC-----HCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV 645
C D + S +N C C NF+ C + + + +CD +
Sbjct: 1452 PECQEDAGNKVCSLQCNNHACGWDGGDCSLNFND-PWKNCTQSLQCWKYFSDGHCDSQ-- 1508
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY--WNLQEYNPFGCEQCNCNLA 698
+ AGC + G CQ R +G+ C PLY + ++ C+Q CN A
Sbjct: 1509 -CNSAGC--LFDGFDCQ---RAEGQ----CNPLYDQYCKDHFSDGHCDQ-GCNSA 1552
Score = 65.3 bits (152), Expect = 4e-09
Identities = 83/329 (25%), Positives = 117/329 (35%), Gaps = 55/329 (16%)
Query: 1767 CNGHSDQCDVNTGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CN + D+C N C N C D G C C GYH + +C C
Sbjct: 675 CNINIDECAGNP--CHNGGTCEDGINGFTCR-CPEGYHDPTCLSEVNECNSNPCVHG--- 728
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPC-- 1877
+C S NG C+C PG+ G C+ C + T Y C
Sbjct: 729 -----ACRDSLNG--YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE 781
Query: 1878 -----NCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAP--GFYGDAIFSKNCTAC 1930
NC NIN C +N C+++ AG CN P G + + + C
Sbjct: 782 GFSGPNCQTNINECASNPC--LNQGT--CIDDVAGYKCNCLLPYTGATCEVVLAP-CAPS 836
Query: 1931 ICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC 1988
C G D + +CVC G G+ C+ +N + +PC G + ++T
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEV------DINECV-LSPCRHGASCQNTH- 888
Query: 1989 DDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGV 2048
+C C G +G+ C+ D C C+ G S N T C+CLPG
Sbjct: 889 --GGYRCHCQAGYSGRNCETDI--------DDCRPNPCHNGGSCTDGIN-TAFCDCLPGF 937
Query: 2049 IGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
G C+ P C C D+
Sbjct: 938 RGTFCEEDINECASDPCRNGANCTDCVDS 966
Score = 65.3 bits (152), Expect = 4e-09
Identities = 88/363 (24%), Positives = 122/363 (33%), Gaps = 66/363 (18%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCS--------SCAYGYFDYPNCKPCT--CNL 410
C C P F+ C+ + C+ +P C +C GY PNC+ C+
Sbjct: 1007 CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTG-PNCQNLVHWCDS 1065
Query: 411 NGTE-GEHC--TPTDGLCPCKYNYAGKSCEI----CEDGYYSPECKNCECNTVGSVSYVC 463
+ + G C T T C C + G C++ CE G +
Sbjct: 1066 SPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1125
Query: 464 DKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAG 521
T C C++ Y+G C C P C T C D G C C AG
Sbjct: 1126 GN-THHCRCQAGYTGSYCEDL------VDECSPSPCQNGAT----CTDYLGGYSCKCVAG 1174
Query: 522 FGGPRC----DQCLS-------------GYYMQVLGRERQCVPC--NCDPTGSTSTSCSA 562
+ G C D+CLS Y R Q V C N D S
Sbjct: 1175 YHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSR 1234
Query: 563 DGKC----NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFD 618
KC C+ GG C C PG+ C DV+ + + CD G +C +
Sbjct: 1235 SPKCFNNGTCVDQVGGYSC-TCPPGFVGE----RCEGDVNECLSNPCDARGTQNCVQRVN 1289
Query: 619 GAKCDTCREQFYNYPACEE----CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-N 673
C+ CR + CE C P + A + G +C+C +G C N
Sbjct: 1290 DFHCE-CRAG-HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN 1347
Query: 674 DCK 676
D +
Sbjct: 1348 DAR 1350
Score = 64.1 bits (149), Expect = 9e-09
Identities = 114/460 (24%), Positives = 156/460 (33%), Gaps = 75/460 (16%)
Query: 360 PCQCDPHFSTGNCEEESGR------CECRPEFQPPDCSSCAYGYFDYPNCKPCTCN--LN 411
PC P + G C R C C F P C + P C N N
Sbjct: 62 PCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT--------PLDNACLTNPCRN 113
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + T T+ C C ++GKSC+ + +P +C SY+C
Sbjct: 114 GGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPF-EASYICH------- 165
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQ 529
C + G TC Q N KP C GT C + G +C+C+A GP C++
Sbjct: 166 CPPSFHGPTCRQ----DVNECGQKPGLCRHGGT----CHNEVGSYRCVCRATHTGPNCER 217
Query: 530 ---------CLSGYYMQVLG---RERQCVP----CNCDPT--GSTSTSCSADGKCNCLTN 571
C +G + G E C+P NC+ +C G C N
Sbjct: 218 PYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN 277
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCDD--NGL-CHCKSNFDGAKCDTCRE 627
+C G Y D C + G TC + G C C + + G C +
Sbjct: 278 TYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENID 337
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN-----DCKPLYWNL 682
+ C R V + + C G LC D CN D P+
Sbjct: 338 DCASAACFHGATCHDR-VASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGA--CNTKSGQCVCKQHVGERQCDQCLDGFYRLQTN-D 739
P G C+ SLGA C +G+C+ +G +C QCL G+ + D
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCE-HAGKCI--NTLGSFEC-QCLQGYTGPRCEID 452
Query: 740 VFGCTECDCDIGGSIDNNCDKTTG--QCHCHSRVEGRRCD 777
V C C D C G QC C EG C+
Sbjct: 453 VNECVSNPC----QNDATCLDQIGEFQCICMPGYEGVHCE 488
Score = 60.5 bits (140), Expect = 1e-07
Identities = 89/370 (24%), Positives = 132/370 (35%), Gaps = 48/370 (12%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
+++EC + G +CE G R P G+ P C ++C+ N + C D+ G
Sbjct: 678 NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPT-CLSEVNECNSNPCVHGACRDSLNG 736
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C G+ G +C C N D++ C C+ G+ G
Sbjct: 737 YKCD-CDPGWSGTNCDINNNECESNPCV------NGGTCKDMTSG---YVCTCREGFSGP 786
Query: 1851 RCEY----CAAGYYGIPEDT--DLHTGDYCK------PCNCSGNINPQDPGSCDSINGDC 1898
C+ CA+ + + T D G C C + P P C + G+C
Sbjct: 787 NCQTNINECASNPC-LNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN-GGEC 844
Query: 1899 LKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG--TCVCRPGVI 1954
+ + +C +C G+ G + C C G A C +T G C C+ G
Sbjct: 845 RQS-EDYESFSC-VCPTGWQGQTCEVDINECVLSPC-RHG-ASCQNTHGGYRCHCQAGYS 900
Query: 1955 GEKC----DRCAPD--HWG--LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC 2006
G C D C P+ H G G+ C+C T C++D +C G C
Sbjct: 901 GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC 960
Query: 2007 DQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV-LI 2063
C + G HC NT C G C+ G+ C CP +
Sbjct: 961 TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG--TCVDGINSFTC-LCPPGFTGSY 1017
Query: 2064 PQEGCLECDS 2073
Q ECDS
Sbjct: 1018 CQHDVNECDS 1027
Score = 60.1 bits (139), Expect = 1e-07
Identities = 92/361 (25%), Positives = 131/361 (36%), Gaps = 77/361 (21%)
Query: 1735 ECQCPRAYRGLSCEQ--------CAEGHYRLPSGFCVPCQC--NGHSDQC--DVN----- 1777
+C+CP + G SC+Q CA G LP C C + H C DVN
Sbjct: 126 KCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK 185
Query: 1778 TGICLN--CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
G+C + N +G + C + + G R + C+ P P N +C
Sbjct: 186 PGLCRHGGTCHNEVGSYRCVCRATHTGP---NCERPYVPCS---PSPCQNGG-TC--RPT 236
Query: 1836 GSLI-SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC------SGNINPQDP 1888
G + C C PG+ G CE G D NC +G +D
Sbjct: 237 GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDV 296
Query: 1889 GSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDST 1943
C + C C N G C +C G+ G+ +C + C F A C
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNC-VCVNGWTGEDCSENIDDCASAAC--FHGATCHDR 353
Query: 1944 TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRC 1997
+ C C G G C LN PCN E + CD + NG+ C C
Sbjct: 354 VASFYCECPHGRTGLLCH--------LNDACISNPCN-----EGSNCDTNPVNGKAICTC 400
Query: 1998 AKGVTGKQC----DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G TG C D+C+ G + C+H G + + + +C+CL G G +C
Sbjct: 401 PSGYTGPACSQDVDECSLG-----ANPCEH----AGKCINTL--GSFECQCLQGYTGPRC 449
Query: 2054 D 2054
+
Sbjct: 450 E 450
Score = 56.8 bits (131), Expect = 1e-06
Identities = 83/336 (24%), Positives = 116/336 (34%), Gaps = 51/336 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFC------VPCQC-NGHSD-QCDVNTGICLNC 1784
C CP+ Y G +C+ P G C C+C +G + CDV + C
Sbjct: 1045 CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1104
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFA-LSCDLSENGSLISCNC 1843
A D C HG V + C C Y + L + S + C
Sbjct: 1105 AQRQGVDVARLCQ---HGGLCVDAG-NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 1160
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC-DSINGDCLKCV 1902
GG C+ C AGY+G+ ++ D C C Q+ G+C D N C
Sbjct: 1161 TDYLGGYSCK-CVAGYHGVNCSEEI---DECLSHPC------QNGGTCLDLPNTYKCSCP 1210
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTG--TCVCRPGVIGEKCDR 1960
T G C + C F C G +C C PG +GE+C+
Sbjct: 1211 RGTQGVHCEINVDDCNPPVDPVSRSPKC----FNNGTCVDQVGGYSCTCPPGFVGERCE- 1265
Query: 1961 CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG 2020
+N L PC+ Q +D C C G TG++C+ +G
Sbjct: 1266 -----GDVNECLS-NPCDARGTQNCVQRVND-FHCECRAGHTGRRCESVI--------NG 1310
Query: 2021 CDHCNCNTGYSVGFMCN-ATG-QCECLPGVIGEKCD 2054
C C G + N A G C+C G G C+
Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 54.8 bits (126), Expect = 6e-06
Identities = 77/304 (25%), Positives = 105/304 (34%), Gaps = 56/304 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHS-DQCDVNTGICLNCADNTIGDHC 1793
C+CP + GL C+ +PS C V Q G + + G+C++ A NT HC
Sbjct: 1083 CECPSGWTGLYCD--------VPSVSCEVAAQRQGVDVARLCQHGGLCVD-AGNT--HHC 1131
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C +GY G +C P P N A D SC C GY G C
Sbjct: 1132 R-CQAGYTGSYCEDLVDEC------SPSPCQNGATCTDYLGG---YSCKCVAGYHGVNCS 1181
Query: 1854 Y---------CAAG--YYGIPEDTDLHTGDYCKPCNCSGNIN----PQDPGSCDSINGDC 1898
C G +P + +C N++ P DP S +
Sbjct: 1182 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1241
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGT--CVCRPGVI 1954
CV+ G +C C PGF G+ C + CD G +C C CR G
Sbjct: 1242 GTCVDQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 1300
Query: 1955 GEKCDRCAPDHWGL------------NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G +C+ G NT G C C E C++D C + +
Sbjct: 1301 GRRCESVINGCKGKPCKNGGTCAVASNTARGFI-CKCPAGFEGATCENDARTCGSLRCLN 1359
Query: 2003 GKQC 2006
G C
Sbjct: 1360 GGTC 1363
Score = 52.4 bits (120), Expect = 3e-05
Identities = 70/249 (28%), Positives = 90/249 (36%), Gaps = 42/249 (16%)
Query: 1315 SPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
+P G CR+++ + + G CD + + E E N CK G C+ CR
Sbjct: 723 NPCVHGACRDSLNGYKCDCDPGWSGTNCD-INNNECESNPCVNGGTCKDMTSGYVCT-CR 780
Query: 1375 TGYYGFPNCR---------PCHCPSTAICDDNGM-CICPKNVEGENCD----RCKPYTF- 1419
G+ G PNC+ PC T I D G C C G C+ C P
Sbjct: 781 EGFSG-PNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 1420 NFDVQRGCDD-----CNCNPLGVVGNQLQCEADSGKCA---CR-----ENVRGRVCDHCV 1466
N R +D C C P G G CE D +C CR +N G HC
Sbjct: 840 NGGECRQSEDYESFSCVC-PTGWQGQT--CEVDINECVLSPCRHGASCQNTHGGYRCHCQ 896
Query: 1467 PGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQD 1520
G+ DC C+ G+ D NTA C C RG C+ E +
Sbjct: 897 AGYSGRNCETDIDDCRPNPCHNGGSCTDGI--NTAFCDCLPGFRGTFCEEDINECASDPC 954
Query: 1521 DNPDGCTKC 1529
N CT C
Sbjct: 955 RNGANCTDC 963
Score = 51.6 bits (118), Expect = 5e-05
Identities = 86/351 (24%), Positives = 117/351 (33%), Gaps = 65/351 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
+C CPR +G+ CE + C P S +C N G C++ +G +
Sbjct: 1206 KCSCPRGTQGVHCEINVDD--------CNPPVDPVSRSPKC-FNNGTCVD----QVGGYS 1252
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G+ G+ G +CL C N C N C C+ G+ G RCE
Sbjct: 1253 CTCPPGFVGERCEGDVNECLSNPCDARGTQN-----CVQRVND--FHCECRAGHTGRRCE 1305
Query: 1854 YCAAGYYGIP--------EDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLK---C 1901
G G P ++ G CK P G D +C S+ CL C
Sbjct: 1306 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR--CLNGGTC 1363
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKNCTACICDE--FGMADCDSTTGT----CVCRPGVIG 1955
++ C LC F G + C+ + C+ T+ + C+C G
Sbjct: 1364 ISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 1422
Query: 1956 EKCDRCAPDHWGLNTGLGCTP-----------CN-------CGIASESTQCDDDNGQCRC 1997
C +G G P C C + + C D G C
Sbjct: 1423 LLC-HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSL 1481
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDG-CD-HCNCNTGYSVGFMC-NATGQCECL 2045
K C Q + W Y DG CD CN GF C A GQC L
Sbjct: 1482 NFNDPWKNCTQ-SLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPL 1531
Score = 50.0 bits (114), Expect = 2e-04
Identities = 86/350 (24%), Positives = 123/350 (35%), Gaps = 51/350 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVPCQCNGHSDQCDVN-TGICLNCADNTIG 1790
EC C + G +CE+ + G+ G CV N ++ +C TG C ++
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGACVD-GVNTYNCRCPPEWTG--QYCTEDV-- 296
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
D C+ + T C C + D SEN + C + GA
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGE------DCSEN--IDDCASAACFHGA 348
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAA 1909
C A +Y E TG C N + NP + GS CD+ N G A
Sbjct: 349 TCHDRVASFYC--ECPHGRTGLLCH-LNDACISNPCNEGSNCDT---------NPVNGKA 396
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C G+ G A S++ C G C+ G C+ G +C +C + G
Sbjct: 397 ICTCPSGYTGPAC-SQDVDEC---SLGANPCEHA-GKCINTLGSF--EC-QCLQGYTGPR 448
Query: 1970 TGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQC----DQCAAGFWNYTKDGCD- 2022
+ C C D G QC C G G C D+CA+ + D
Sbjct: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
Query: 2023 ----HCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEG 2067
C C TG++ G +C +C P G KC P + + EG
Sbjct: 509 INEFQCECPTGFT-GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEG 557
Score = 47.6 bits (108), Expect = 8e-04
Identities = 63/237 (26%), Positives = 86/237 (36%), Gaps = 41/237 (17%)
Query: 1877 CNCSGN-INP--QDPGSCDSI---NGDCLKCVNN--TAGAACNLCAPGFYGDAIFSKNCT 1928
C C G + P QDP C S N V+ A AC+ CA GF G +
Sbjct: 46 CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACS-CALGFSGPLCLTPLDN 104
Query: 1929 ACI---CDEFGMADCDSTTG-TCVCRPGVIGEKC---DRCAPDHWGLNTGLGCTP----- 1976
AC+ C G D + T C C PG G+ C D CA + G C P
Sbjct: 105 ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA--NGGQCLPFEASY 162
Query: 1977 -CNCGIASESTQCDDDNGQCRCAKGVT--GKQCDQCAAGFW-----NYTKDGCDH----C 2024
C+C + C D +C G+ G C + +T C+ C
Sbjct: 163 ICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC 222
Query: 2025 N---CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C G + + T +C CLPG G+ C+ E P C +C D +
Sbjct: 223 SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE---ENIDDCPGNNCKNGGACVDGV 276
Score = 45.2 bits (102), Expect = 0.005
Identities = 50/197 (25%), Positives = 67/197 (34%), Gaps = 28/197 (14%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-----CDDNGMCICPKNVEGEN 1410
GG C PN +C G + N C+ P + C +NG C+ V G +
Sbjct: 1195 GGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV--DQVGGYS 1252
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQC--EADSGKCACRENVRGRVCDHCVPG 1468
C C P + ++C NP G Q C + C CR GR C+ + G
Sbjct: 1253 CT-CPPGFVGERCEGDVNECLSNPCDARGTQ-NCVQRVNDFHCECRAGHTGRRCESVING 1310
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQ---CYCKTNVRGQACDTCKEEYFNLQDDNPDG 1525
C C GT NTA+ C C G C+ +L+ N
Sbjct: 1311 ------CKGKPCKNGGTC--AVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1362
Query: 1526 CTK------CFCFGKTT 1536
C C C G T
Sbjct: 1363 CISGPRSPTCLCLGPFT 1379
Score = 44.0 bits (99), Expect = 0.010
Identities = 59/265 (22%), Positives = 87/265 (32%), Gaps = 55/265 (20%)
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C C GF GP C L + C+ C G+ + KC C + G
Sbjct: 87 CSCALGFSGPLCLTPL----------DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
C Q P C S C +G + + +CHC +F G TCR+
Sbjct: 137 SCQQADP-------CASNPC-ANGGQCLPFEASYICHCPPSFHG---PTCRQD------V 179
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
EC P G+ C + C C+ G C + Y P C C
Sbjct: 180 NECGQKP-GLCRHGGTCHNEVGSYRCVCRATHTGPNCE---------RPYVP--CSPSPC 227
Query: 696 NLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSID 755
GT G + +C C + C++ +D C +C GG+
Sbjct: 228 QNGGTCRPTG---DVTHECACLPGFTGQNCEENID-----------DCPGNNCKNGGACV 273
Query: 756 NNCDKTTGQCHCHSRVEGRRCDQPI 780
+ + T C C G+ C + +
Sbjct: 274 DGVN--TYNCRCPPEWTGQYCTEDV 296
Score = 43.6 bits (98), Expect = 0.014
Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 27/187 (14%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRP--CHCP 1389
C C G T C +C P G TC+ C GY+G NC C
Sbjct: 1131 CRCQ-AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGV-NCSEEIDECL 1188
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
S C + G C+ N +C R T + DDCN P+ V +C ++G
Sbjct: 1189 SHP-CQNGGTCLDLPNTYKCSCPRG---TQGVHCEINVDDCN-PPVDPVSRSPKC-FNNG 1242
Query: 1450 KCACRENVRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
C + V G C C PG +C C+ GT V N C C+
Sbjct: 1243 TCV--DQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1299
Query: 1504 RGQACDT 1510
G+ C++
Sbjct: 1300 TGRRCES 1306
Score = 41.5 bits (93), Expect = 0.056
Identities = 69/286 (24%), Positives = 92/286 (32%), Gaps = 44/286 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C Y G++C + + PCQ NG + NT C +C T G HCE
Sbjct: 1169 CKCVAGYHGVNCSE------EIDECLSHPCQ-NGGTCLDLPNTYKC-SCPRGTQGVHCEI 1220
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
+ DC P+ F + + G SC C PG+ G RCE
Sbjct: 1221 NVD------------DCNPPVDPVSRSPKCFNNGTCVDQVGGY-SCTCPPGFVGERCEGD 1267
Query: 1856 AAGYYGIPEDTD------LHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCLKCV 1902
P D D+ C C IN C + G C
Sbjct: 1268 VNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN-GGTCAVAS 1326
Query: 1903 NNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDR 1960
N G C C GF G ++ C + C G + TC+C G +C
Sbjct: 1327 NTARGFICK-CPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF 1385
Query: 1961 CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC 2006
A + LG PC E T + +C C G C
Sbjct: 1386 PAS-----SPCLGGNPCYNQGTCEPTS-ESPFYRCLCPAKFNGLLC 1425
Score = 41.1 bits (92), Expect = 0.073
Identities = 51/183 (27%), Positives = 63/183 (34%), Gaps = 35/183 (19%)
Query: 1361 CKPNVIGRTCSACRTGYYG------FPNC--RPCHCPSTAICDDNG-MCICPKNVEGENC 1411
CK V TC CR GY G C +PC T DN +C C K G NC
Sbjct: 580 CKDGVATFTC-LCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Query: 1412 DRCKPYTFNFDVQRG-CDD------CNCNPLGVVGNQLQCEADSGKCA---------CRE 1455
+ + G C D C C P G G+ C + +CA C +
Sbjct: 639 EINLDDCASSPCDSGTCLDKIDGYECACEP-GYTGS--MCNINIDECAGNPCHNGGTCED 695
Query: 1456 NVRGRVCDHCVPGHYAFPDCYQ--CTCNRHGTTYDVC--DQNTAQCYCKTNVRGQACDTC 1511
+ G C C P Y P C CN + + C N +C C G CD
Sbjct: 696 GINGFTC-RC-PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN 753
Query: 1512 KEE 1514
E
Sbjct: 754 NNE 756
Score = 39.9 bits (89), Expect = 0.17
Identities = 53/210 (25%), Positives = 69/210 (32%), Gaps = 29/210 (13%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
RP C GS NT C C P G C P +C C D+
Sbjct: 912 RPNPCHNGGSCTDGINT--AFCDCLPGFRGTFCEEDINECASDPCRNGANCTD---CVDS 966
Query: 1398 GMCICPKNVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQCEADSG 1449
C CP G +C+ P G C D C C P G G+ C+ D
Sbjct: 967 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPP-GFTGS--YCQHDVN 1023
Query: 1450 KCACRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C + + G C D C Y+CTC + G T C C G C
Sbjct: 1024 ECDSQPCLHGGTCQDGC--------GSYRCTCPQ-GYTGPNCQNLVHWCDSSPCKNGGKC 1074
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRC 1538
+Y + + P G T +C + C
Sbjct: 1075 WQTHTQY---RCECPSGWTGLYCDVPSVSC 1101
Score = 39.9 bits (89), Expect = 0.17
Identities = 61/256 (23%), Positives = 85/256 (33%), Gaps = 31/256 (12%)
Query: 1299 YTREFIEQCASYNYYISPNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTF-G 1356
+ E I +CAS P G C + + S T +G C+ E + F G
Sbjct: 941 FCEEDINECAS-----DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG 995
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCH---CPSTAICDD---NGMCICPKNVEGEN 1410
G C N C TG Y + C C C D + C CP+ G N
Sbjct: 996 GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN 1055
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGV---VGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C ++ CD C G Q +CE SG +V C+ V
Sbjct: 1056 CQ---------NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE--VA 1104
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
D + C G D NT C C+ G C+ +E N CT
Sbjct: 1105 AQRQGVDVARL-CQHGGLCVDA--GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCT 1161
Query: 1528 KCFCFGKTTRCSSSYY 1543
+ G + +C + Y+
Sbjct: 1162 D-YLGGYSCKCVAGYH 1176
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 93.9 bits (223), Expect = 1e-17
Identities = 155/638 (24%), Positives = 219/638 (34%), Gaps = 107/638 (16%)
Query: 211 DPTVTRRYFYSIKDISIGGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCN 266
DPT + + G C NG+ C+P N +I C+ N C G C
Sbjct: 710 DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCK 769
Query: 267 KCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCL 326
SG+ + + FS NC + EC +P +++ D+ G KC
Sbjct: 770 DMTSGY------VCTCREGFSGP--NCQTNINECASNPCLNQGTCIDDV-----AGYKC- 815
Query: 327 NCQHNTEGINCN----KCRPTYYRPYGK-RWDELDVCQPCQCDPHFSTGNCEEESGRCEC 381
NC G C C P+ R G+ R E C C + CE + C
Sbjct: 816 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVL 875
Query: 382 RPEFQPPDCSS--------CAYGYF------DYPNCKPCTCNLNGTEGEHCTP--TDGLC 425
P C + C GY D +C+P C+ G+ CT C
Sbjct: 876 SPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS----CTDGINTAFC 931
Query: 426 PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQ 485
C + G CE ED EC + C + + D T CTC + +SG C
Sbjct: 932 DCLPGFRGTFCE--ED---INECASDPCRNGANCTDCVDSYT--CTCPAGFSGIHCEN-- 982
Query: 486 AGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
N P C +C GT D ++ C+C GF G C ++ Q
Sbjct: 983 ----NTPDCTESSCFNGGT---CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGT 1035
Query: 545 CVP------CNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQ--------CSPGYYK-YP 588
C C C P G T +C + C+ G +C Q C G+ Y
Sbjct: 1036 CQDGCGSYRCTC-PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
Query: 589 DCLSCNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP- 642
D S +C+V+ + C GLC N +C Y +EC+ P
Sbjct: 1095 DVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPC 1154
Query: 643 -RGVTAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G T + + G C V C + + + + C+ L N + C C
Sbjct: 1155 QNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS-CPRGT 1213
Query: 698 AGTLNSLGA--CN------TKSGQC----VCKQHVGERQCDQCLDGFYRLQTN-DVFGCT 744
G + CN ++S +C C VG C C GF + DV C
Sbjct: 1214 QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT-CPPGFVGERCEGDVNECL 1272
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRV--EGRRCDQPI 780
CD G+ NC + HC R GRRC+ I
Sbjct: 1273 SNPCDARGT--QNCVQRVNDFHCECRAGHTGRRCESVI 1308
Score = 93.1 bits (221), Expect = 2e-17
Identities = 139/570 (24%), Positives = 188/570 (32%), Gaps = 112/570 (19%)
Query: 236 HADTCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWDRF--SCEP 290
H TC+ D N +C C T GP C C+ D + +CEP
Sbjct: 614 HGGTCQDRD-----NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEP 668
Query: 291 ----CNCHNHTTECTYDPEIDEKRLSLDING---RYEGGGKCLNCQHNTEGINCNKCRPT 343
C+ + EC +P + ING R G C N N C
Sbjct: 669 GYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC--- 725
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGY------ 397
+G D L+ + C CDP +S NC+ + CE P C GY
Sbjct: 726 ---VHGACRDSLNGYK-CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE 781
Query: 398 -FDYPNCK----PCTCNLNGTEGEHCTPTDGL-CPCKYNYAGKSCEICEDGYYSPECKNC 451
F PNC+ C N +G G C C Y G +CE+ +P C
Sbjct: 782 GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEV----VLAP-CAPS 836
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
C G D + C C + + G+TC N PC S C +
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEV----DINECVLSPCRHGAS------CQN 886
Query: 512 VSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
G +C C+AG+ G C+ + C P C GS + + C+CL
Sbjct: 887 THGGYRCHCQAGYSGRNCETDID-----------DCRPNPCHNGGSCTDGINT-AFCDCL 934
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
F G C++ +C S C +G+ + C D+ C C + F G C+
Sbjct: 935 PGFRGTFCEE------DINECASDPCR-NGANCTDCVDSYTCTCPAGFSGIHCEN----- 982
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
N P C E +C G G S C C G C +++
Sbjct: 983 -NTPDCTESSCFNGGTCVD--GINSF----TCLCPPGFTGSYC-----------QHDVNE 1024
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD 749
C+ C GT C S +C C Q C N V C C
Sbjct: 1025 CDSQPCLHGGTCQD--GCG--SYRCTCPQGYTGPNCQ-----------NLVHWCDSSPCK 1069
Query: 750 IGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
GG T +C C S G CD P
Sbjct: 1070 NGGKCWQT--HTQYRCECPSGWTGLYCDVP 1097
Score = 85.0 bits (201), Expect = 5e-15
Identities = 137/569 (24%), Positives = 198/569 (34%), Gaps = 98/569 (17%)
Query: 253 VCRCQHNTCGPQCNK----CCSGFE--QKKWRISQNWDRFSCEPCN------CHNHTTEC 300
+C C GP C++ C G + + F C+ C EC
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC 456
Query: 301 TYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINC----NKCRPTYYRPYGKRWDELD 356
+P LD G ++ C+ C EG++C ++C + G+ D+++
Sbjct: 457 VSNP-CQNDATCLDQIGEFQ----CI-CMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
Query: 357 VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGE 416
Q C+C F+ C+ + C P C D PN C C G G
Sbjct: 511 EFQ-CECPTGFTGHLCQYDVDECASTPCKNGAKC-------LDGPNTYTCVCT-EGYTGT 561
Query: 417 HCTPTDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCK 473
HC C PC Y C+DG + C C G + C+ +C+ +
Sbjct: 562 HCEVDIDECDPDPCHYGS-------CKDGVAT---FTCLCRP-GYTGHHCETNINECSSQ 610
Query: 474 SKYSGRTCNQCQAGYYNY-------PTCKPC--NCDTSGTEPSIC-DDVSG-QCICKAGF 522
G TC Y + P C+ +C +S + C D + G +C C+ G+
Sbjct: 611 PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGY 670
Query: 523 GGPRC----DQCLSGYYMQVLGRERQCV---PCNCDPTGSTSTSCSAD-GKCNCLTNFGG 574
G C D+C +G G + C C P G +C ++ +CN G
Sbjct: 671 TGSMCNINIDEC-AGNPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECNSNPCVHG 728
Query: 575 AQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPA 634
A C GY C+CD S G+ CD N C+SN TC++ Y
Sbjct: 729 A-CRDSLNGY-------KCDCDPGWS-GTNCDINNN-ECESN-PCVNGGTCKDMTSGYVC 777
Query: 635 -CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
C E P T + C S P C D V G CN P E C
Sbjct: 778 TCREGFSGPNCQT-NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPS 836
Query: 694 NCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGS 753
C G + + +S CVC + C+ D+ C C G S
Sbjct: 837 PCRNGGECRQ--SEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGAS 883
Query: 754 IDNNCDKTTG--QCHCHSRVEGRRCDQPI 780
C T G +CHC + GR C+ I
Sbjct: 884 ----CQNTHGGYRCHCQAGYSGRNCETDI 908
Score = 82.2 bits (194), Expect = 3e-14
Identities = 123/502 (24%), Positives = 177/502 (35%), Gaps = 83/502 (16%)
Query: 321 GGGKCLNCQHNTEGINCNK----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES 376
G +C+ C+ G NC + C P+ + G DV C C P F+ NCEE
Sbjct: 200 GSYRCV-CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA--GK 434
C P + +C G Y NC+ C T G++CT C N G
Sbjct: 259 DDC---PGNNCKNGGACVDGVNTY-NCR---CPPEWT-GQYCTEDVDECQLMPNACQNGG 310
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY----N 490
+C GY NC C G C + DC + + G TC+ A +Y +
Sbjct: 311 TCHNTHGGY------NCVC-VNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 491 YPTCKPCNCDTS-----GTEPSICD--DVSGQ--CICKAGFGGPRC----DQCL------ 531
T C+ + + E S CD V+G+ C C +G+ GP C D+C
Sbjct: 364 GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPC 423
Query: 532 --SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSP 582
+G + LG E QC+ C D S C D CL G QC C P
Sbjct: 424 EHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND--ATCLDQIGEFQC-ICMP 480
Query: 583 GYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
GY + + C + S C NG C K N +C T +EC P
Sbjct: 481 GY----EGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTP 536
Query: 643 RGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
+ A C P C C + G C ++ E +P C +C G
Sbjct: 537 ---CKNGAKCLDGPNTYTCVCTEGYTGTHCE------VDIDECDPDPCHYGSCK-DGVAT 586
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGC--------TECDCDIGGSI 754
C C+ ++ E C G ++ + C C+ ++
Sbjct: 587 FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCA 646
Query: 755 DNNCDKTTGQCHCHSRVEGRRC 776
+ CD T C +++G C
Sbjct: 647 SSPCDSGT----CLDKIDGYEC 664
Score = 81.4 bits (192), Expect = 6e-14
Identities = 140/573 (24%), Positives = 192/573 (33%), Gaps = 90/573 (15%)
Query: 229 GRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCNKCCSGFEQKKWRISQNWD 284
G C+ +G+ CEP NI + C N C G C +GF R + +
Sbjct: 653 GTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF---TCRCPEGYH 709
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEK-RLSLDINGRYEGGGKCLNCQHNTEGINC----NK 339
+P C + EC +P + R SL+ G KC +C G NC N+
Sbjct: 710 ----DP-TCLSEVNECNSNPCVHGACRDSLN-------GYKC-DCDPGWSGTNCDINNNE 756
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFD 399
C G ++ C C FS NC+ C P C GY
Sbjct: 757 CESNPC-VNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY-- 813
Query: 400 YPNC-KPCTCNLNGTEGEHCTPT----DGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
NC P T C P+ G C +Y SC +C G+ + + CE +
Sbjct: 814 KCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSC-VCPTGW---QGQTCEVD 869
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG 514
V C +C++ + G C+ CQAGY + + C D P+ C +
Sbjct: 870 INECVLSPC---RHGASCQNTHGGYRCH-CQAGY----SGRNCETDIDDCRPNPCHNGGS 921
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNF 572
C G CD CL G+ E C DP G+ T C C C F
Sbjct: 922 ---CTDGINTAFCD-CLPGFRGTFC--EEDINECASDPCRNGANCTDCVDSYTCTCPAGF 975
Query: 573 GGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCREQF 629
G C+ PDC +C G TC D + C C F G+ C
Sbjct: 976 SGIHCEN------NTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQ------ 1019
Query: 630 YNYPACEECNCDPRGVTASFAGCGS----VPAGEL-CQCKDRVQGRICNDCKPLYWNLQE 684
++ C+ C G GCGS P G C++ V + CK Q
Sbjct: 1020 HDVNECDSQPCLHGGTCQD--GCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQT 1077
Query: 685 YNPFGCEQCNCNLAGTLNSLGACNTKSGQC-VCKQHVGERQCDQCLDGFYRLQTNDVFGC 743
+ + CE C G C+ S C V Q G C G + + C
Sbjct: 1078 HTQYRCE-CPSGWTGLY-----CDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHC 1131
Query: 744 TECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C GS C+ +C G C
Sbjct: 1132 -RCQAGYTGSY---CEDLVDECSPSPCQNGATC 1160
Score = 79.8 bits (188), Expect = 2e-13
Identities = 137/562 (24%), Positives = 191/562 (33%), Gaps = 109/562 (19%)
Query: 228 GGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
GG C C + TC N LV C + C KC Q + W
Sbjct: 1033 GGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPC-KNGGKCWQTHTQYRCECPSGWTG 1091
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
C+ + C E+ +R +D+ + GG C++ NT +C +C+ Y
Sbjct: 1092 LYCDV-----PSVSC----EVAAQRQGVDVARLCQHGGLCVDAG-NTH--HC-RCQAGYT 1138
Query: 346 RPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSS---------CA 394
Y + D +D C P C + C + G C+C + +CS C
Sbjct: 1139 GSYCE--DLVDECSPSPCQ---NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ 1193
Query: 395 YG--YFDYPNCKPCTCNLNGTEGEHCT--------PTDGL-----C----PCKYNYAGKS 435
G D PN C+C GT+G HC P D + C C G S
Sbjct: 1194 NGGTCLDLPNTYKCSCP-RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYS 1252
Query: 436 CEICEDGYYSPECKN----C---ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C C G+ C+ C C+ G+ + V C C++ ++GR C G
Sbjct: 1253 CT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVING- 1310
Query: 489 YNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
CK C GT + G C C AGF G C+ R C
Sbjct: 1311 -----CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN-----------DARTCGS 1354
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN-CDVSGSIGSTCD 606
C G T S C CL F G +C + CL N C G+ T +
Sbjct: 1355 LRC-LNGGTCISGPRSPTCLCLGPFTGPECQ-----FPASSPCLGGNPCYNQGTCEPTSE 1408
Query: 607 DNGL-CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV--TASFAGCGSVPAGELC-- 661
C C + F+G C Y++ + P + C ++C
Sbjct: 1409 SPFYRCLCPAKFNGLLCHILD---YSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 1465
Query: 662 QCKDRVQGRICNDCKPLY---W-----NLQEYNPFGCEQCN--CNLAGTLNSLGACNTKS 711
QC + G DC + W +LQ + F C+ CN AG L C
Sbjct: 1466 QCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAE 1525
Query: 712 GQC------VCKQHVGERQCDQ 727
GQC CK H + CDQ
Sbjct: 1526 GQCNPLYDQYCKDHFSDGHCDQ 1547
Score = 74.9 bits (176), Expect = 5e-12
Identities = 102/376 (27%), Positives = 133/376 (35%), Gaps = 47/376 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC+ G +C+ G+ GF P C + ++C N CLN C D+ G
Sbjct: 756 ECESNPCVNGGTCKDMTSGYVCTCREGFSGP-NCQTNINECASNP--CLNQGTCIDDVAG 812
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ Y G AT + ++ C P P N C SE+ SC C G+ G
Sbjct: 813 YKCN-CLLPYTG-ATC----EVVLAPCA-PSPCRNGG-ECRQSEDYESFSCVCPTGWQGQ 864
Query: 1851 RCEY----CAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
CE C G Y C NC +I+ P C + G C
Sbjct: 865 TCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN-GGSCT 923
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF-GMADCDSTTG--TCVCRPGVIGE 1956
+N A C+ C PGF G ++ C D A+C TC C G G
Sbjct: 924 DGINT---AFCD-CLPGFRG-TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGI 978
Query: 1957 KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
C+ PD + G T C GI S + C C V +CD
Sbjct: 979 HCENNTPDCTESSCFNGGT-CVDGINSFTCLCPPGFTGSYCQHDVN--ECDSQPCLHGGT 1035
Query: 2017 TKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+DGC C C GY+ N C+ P G KC W Q C EC S
Sbjct: 1036 CQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC------WQTHTQYRC-ECPSG 1088
Query: 2075 TDALIFSVEDLSALLA 2090
L V +S +A
Sbjct: 1089 WTGLYCDVPSVSCEVA 1104
Score = 72.1 bits (169), Expect = 3e-11
Identities = 82/333 (24%), Positives = 117/333 (35%), Gaps = 42/333 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C+CP + G C+ Y + PC+ NG NT C+ C + G HCE
Sbjct: 513 QCECPTGFTGHLCQ------YDVDECASTPCK-NGAKCLDGPNTYTCV-CTEGYTGTHCE 564
Query: 1795 FCMSGYHGDAT-VGTPRD---CLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
+ D G+ +D C C Y ++ C+ + N C+ QP G
Sbjct: 565 VDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHH----CETNIN----ECSSQPCRHGG 616
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C+ Y TG NC N++ CDS G CL ++ G C
Sbjct: 617 TCQDRDNAYLCFCLKGT--TGP-----NCEINLDDCASSPCDS--GTCLDKID---GYEC 664
Query: 1911 NLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC----DRCAPD 1964
C PG+ G I C C G + TC C G C + C +
Sbjct: 665 -ACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSN 723
Query: 1965 ---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
H L C+C T CD +N +C V G C +G+ ++G
Sbjct: 724 PCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF 783
Query: 2022 DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
NC T + Q C+ V G KC+
Sbjct: 784 SGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
Score = 68.9 bits (161), Expect = 3e-10
Identities = 117/475 (24%), Positives = 167/475 (35%), Gaps = 83/475 (17%)
Query: 254 CRCQHNTCGPQC----NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
CRCQ G C ++C Q + +SC+ C H C+ EIDE
Sbjct: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCK-CVAGYHGVNCS--EEIDEC 1187
Query: 310 RLSLDINGRYEGGGKCLN--------CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
++ + GG CL+ C T+G++C P D + C
Sbjct: 1188 -----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV----DPVSRSPKC 1238
Query: 362 QCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
F+ G C ++ G C C P F C D C C+ GT+
Sbjct: 1239 -----FNNGTCVDQVGGYSCTCPPGFVGERCEG------DVNECLSNPCDARGTQNCVQR 1287
Query: 420 PTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG-DCTCKSKYSG 478
D C C+ + G+ CE +G CK C G+ + + G C C + + G
Sbjct: 1288 VNDFHCECRAGHTGRRCESVING-----CKGKPCKNGGTCAVASNTARGFICKCPAGFEG 1342
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQV 538
TC + TC C GT I S C+C F GP C S
Sbjct: 1343 ATCEN------DARTCGSLRCLNGGT--CISGPRSPTCLCLGPFTGPECQFPASS---PC 1391
Query: 539 LGRERQCVPCNCDPTG-STSTSCSADGKCNCLT------NF-GGAQCDQCSPGYYKYPDC 590
LG C+PT S C K N L +F GGA D P + +
Sbjct: 1392 LGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACEL 1451
Query: 591 LSCNCDVSGSIGSTCDDNGLC-----HCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV 645
C D + S +N C C NF+ C + + + +CD +
Sbjct: 1452 PECQEDAGNKVCSLQCNNHACGWDGGDCSLNFND-PWKNCTQSLQCWKYFSDGHCDSQ-- 1508
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY--WNLQEYNPFGCEQCNCNLA 698
+ AGC + G CQ R +G+ C PLY + ++ C+Q CN A
Sbjct: 1509 -CNSAGC--LFDGFDCQ---RAEGQ----CNPLYDQYCKDHFSDGHCDQ-GCNSA 1552
Score = 65.3 bits (152), Expect = 4e-09
Identities = 83/329 (25%), Positives = 117/329 (35%), Gaps = 55/329 (16%)
Query: 1767 CNGHSDQCDVNTGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CN + D+C N C N C D G C C GYH + +C C
Sbjct: 675 CNINIDECAGNP--CHNGGTCEDGINGFTCR-CPEGYHDPTCLSEVNECNSNPCVHG--- 728
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPC-- 1877
+C S NG C+C PG+ G C+ C + T Y C
Sbjct: 729 -----ACRDSLNG--YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE 781
Query: 1878 -----NCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAP--GFYGDAIFSKNCTAC 1930
NC NIN C +N C+++ AG CN P G + + + C
Sbjct: 782 GFSGPNCQTNINECASNPC--LNQGT--CIDDVAGYKCNCLLPYTGATCEVVLAP-CAPS 836
Query: 1931 ICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC 1988
C G D + +CVC G G+ C+ +N + +PC G + ++T
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEV------DINECV-LSPCRHGASCQNTH- 888
Query: 1989 DDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGV 2048
+C C G +G+ C+ D C C+ G S N T C+CLPG
Sbjct: 889 --GGYRCHCQAGYSGRNCETDI--------DDCRPNPCHNGGSCTDGIN-TAFCDCLPGF 937
Query: 2049 IGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
G C+ P C C D+
Sbjct: 938 RGTFCEEDINECASDPCRNGANCTDCVDS 966
Score = 65.3 bits (152), Expect = 4e-09
Identities = 88/363 (24%), Positives = 122/363 (33%), Gaps = 66/363 (18%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCS--------SCAYGYFDYPNCKPCT--CNL 410
C C P F+ C+ + C+ +P C +C GY PNC+ C+
Sbjct: 1007 CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTG-PNCQNLVHWCDS 1065
Query: 411 NGTE-GEHC--TPTDGLCPCKYNYAGKSCEI----CEDGYYSPECKNCECNTVGSVSYVC 463
+ + G C T T C C + G C++ CE G +
Sbjct: 1066 SPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1125
Query: 464 DKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAG 521
T C C++ Y+G C C P C T C D G C C AG
Sbjct: 1126 GN-THHCRCQAGYTGSYCEDL------VDECSPSPCQNGAT----CTDYLGGYSCKCVAG 1174
Query: 522 FGGPRC----DQCLS-------------GYYMQVLGRERQCVPC--NCDPTGSTSTSCSA 562
+ G C D+CLS Y R Q V C N D S
Sbjct: 1175 YHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSR 1234
Query: 563 DGKC----NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFD 618
KC C+ GG C C PG+ C DV+ + + CD G +C +
Sbjct: 1235 SPKCFNNGTCVDQVGGYSC-TCPPGFVGE----RCEGDVNECLSNPCDARGTQNCVQRVN 1289
Query: 619 GAKCDTCREQFYNYPACEE----CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-N 673
C+ CR + CE C P + A + G +C+C +G C N
Sbjct: 1290 DFHCE-CRAG-HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN 1347
Query: 674 DCK 676
D +
Sbjct: 1348 DAR 1350
Score = 64.1 bits (149), Expect = 9e-09
Identities = 114/460 (24%), Positives = 156/460 (33%), Gaps = 75/460 (16%)
Query: 360 PCQCDPHFSTGNCEEESGR------CECRPEFQPPDCSSCAYGYFDYPNCKPCTCN--LN 411
PC P + G C R C C F P C + P C N N
Sbjct: 62 PCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT--------PLDNACLTNPCRN 113
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + T T+ C C ++GKSC+ + +P +C SY+C
Sbjct: 114 GGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPF-EASYICH------- 165
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQ 529
C + G TC Q N KP C GT C + G +C+C+A GP C++
Sbjct: 166 CPPSFHGPTCRQ----DVNECGQKPGLCRHGGT----CHNEVGSYRCVCRATHTGPNCER 217
Query: 530 ---------CLSGYYMQVLG---RERQCVP----CNCDPT--GSTSTSCSADGKCNCLTN 571
C +G + G E C+P NC+ +C G C N
Sbjct: 218 PYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN 277
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCDD--NGL-CHCKSNFDGAKCDTCRE 627
+C G Y D C + G TC + G C C + + G C +
Sbjct: 278 TYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENID 337
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN-----DCKPLYWNL 682
+ C R V + + C G LC D CN D P+
Sbjct: 338 DCASAACFHGATCHDR-VASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGA--CNTKSGQCVCKQHVGERQCDQCLDGFYRLQTN-D 739
P G C+ SLGA C +G+C+ +G +C QCL G+ + D
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCE-HAGKCI--NTLGSFEC-QCLQGYTGPRCEID 452
Query: 740 VFGCTECDCDIGGSIDNNCDKTTG--QCHCHSRVEGRRCD 777
V C C D C G QC C EG C+
Sbjct: 453 VNECVSNPC----QNDATCLDQIGEFQCICMPGYEGVHCE 488
Score = 60.5 bits (140), Expect = 1e-07
Identities = 89/370 (24%), Positives = 132/370 (35%), Gaps = 48/370 (12%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
+++EC + G +CE G R P G+ P C ++C+ N + C D+ G
Sbjct: 678 NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPT-CLSEVNECNSNPCVHGACRDSLNG 736
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C G+ G +C C N D++ C C+ G+ G
Sbjct: 737 YKCD-CDPGWSGTNCDINNNECESNPCV------NGGTCKDMTSG---YVCTCREGFSGP 786
Query: 1851 RCEY----CAAGYYGIPEDT--DLHTGDYCK------PCNCSGNINPQDPGSCDSINGDC 1898
C+ CA+ + + T D G C C + P P C + G+C
Sbjct: 787 NCQTNINECASNPC-LNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN-GGEC 844
Query: 1899 LKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG--TCVCRPGVI 1954
+ + +C +C G+ G + C C G A C +T G C C+ G
Sbjct: 845 RQS-EDYESFSC-VCPTGWQGQTCEVDINECVLSPC-RHG-ASCQNTHGGYRCHCQAGYS 900
Query: 1955 GEKC----DRCAPD--HWG--LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC 2006
G C D C P+ H G G+ C+C T C++D +C G C
Sbjct: 901 GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC 960
Query: 2007 DQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV-LI 2063
C + G HC NT C G C+ G+ C CP +
Sbjct: 961 TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG--TCVDGINSFTC-LCPPGFTGSY 1017
Query: 2064 PQEGCLECDS 2073
Q ECDS
Sbjct: 1018 CQHDVNECDS 1027
Score = 60.1 bits (139), Expect = 1e-07
Identities = 92/361 (25%), Positives = 131/361 (36%), Gaps = 77/361 (21%)
Query: 1735 ECQCPRAYRGLSCEQ--------CAEGHYRLPSGFCVPCQC--NGHSDQC--DVN----- 1777
+C+CP + G SC+Q CA G LP C C + H C DVN
Sbjct: 126 KCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK 185
Query: 1778 TGICLN--CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
G+C + N +G + C + + G R + C+ P P N +C
Sbjct: 186 PGLCRHGGTCHNEVGSYRCVCRATHTGP---NCERPYVPCS---PSPCQNGG-TC--RPT 236
Query: 1836 GSLI-SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNC------SGNINPQDP 1888
G + C C PG+ G CE G D NC +G +D
Sbjct: 237 GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDV 296
Query: 1889 GSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDST 1943
C + C C N G C +C G+ G+ +C + C F A C
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNC-VCVNGWTGEDCSENIDDCASAAC--FHGATCHDR 353
Query: 1944 TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRC 1997
+ C C G G C LN PCN E + CD + NG+ C C
Sbjct: 354 VASFYCECPHGRTGLLCH--------LNDACISNPCN-----EGSNCDTNPVNGKAICTC 400
Query: 1998 AKGVTGKQC----DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G TG C D+C+ G + C+H G + + + +C+CL G G +C
Sbjct: 401 PSGYTGPACSQDVDECSLG-----ANPCEH----AGKCINTL--GSFECQCLQGYTGPRC 449
Query: 2054 D 2054
+
Sbjct: 450 E 450
Score = 56.8 bits (131), Expect = 1e-06
Identities = 83/336 (24%), Positives = 116/336 (34%), Gaps = 51/336 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFC------VPCQC-NGHSD-QCDVNTGICLNC 1784
C CP+ Y G +C+ P G C C+C +G + CDV + C
Sbjct: 1045 CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1104
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFA-LSCDLSENGSLISCNC 1843
A D C HG V + C C Y + L + S + C
Sbjct: 1105 AQRQGVDVARLCQ---HGGLCVDAG-NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 1160
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC-DSINGDCLKCV 1902
GG C+ C AGY+G+ ++ D C C Q+ G+C D N C
Sbjct: 1161 TDYLGGYSCK-CVAGYHGVNCSEEI---DECLSHPC------QNGGTCLDLPNTYKCSCP 1210
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTG--TCVCRPGVIGEKCDR 1960
T G C + C F C G +C C PG +GE+C+
Sbjct: 1211 RGTQGVHCEINVDDCNPPVDPVSRSPKC----FNNGTCVDQVGGYSCTCPPGFVGERCE- 1265
Query: 1961 CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG 2020
+N L PC+ Q +D C C G TG++C+ +G
Sbjct: 1266 -----GDVNECLS-NPCDARGTQNCVQRVND-FHCECRAGHTGRRCESVI--------NG 1310
Query: 2021 CDHCNCNTGYSVGFMCN-ATG-QCECLPGVIGEKCD 2054
C C G + N A G C+C G G C+
Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 54.8 bits (126), Expect = 6e-06
Identities = 77/304 (25%), Positives = 105/304 (34%), Gaps = 56/304 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHS-DQCDVNTGICLNCADNTIGDHC 1793
C+CP + GL C+ +PS C V Q G + + G+C++ A NT HC
Sbjct: 1083 CECPSGWTGLYCD--------VPSVSCEVAAQRQGVDVARLCQHGGLCVD-AGNT--HHC 1131
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C +GY G +C P P N A D SC C GY G C
Sbjct: 1132 R-CQAGYTGSYCEDLVDEC------SPSPCQNGATCTDYLGG---YSCKCVAGYHGVNCS 1181
Query: 1854 Y---------CAAG--YYGIPEDTDLHTGDYCKPCNCSGNIN----PQDPGSCDSINGDC 1898
C G +P + +C N++ P DP S +
Sbjct: 1182 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1241
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGT--CVCRPGVI 1954
CV+ G +C C PGF G+ C + CD G +C C CR G
Sbjct: 1242 GTCVDQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 1300
Query: 1955 GEKCDRCAPDHWGL------------NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G +C+ G NT G C C E C++D C + +
Sbjct: 1301 GRRCESVINGCKGKPCKNGGTCAVASNTARGFI-CKCPAGFEGATCENDARTCGSLRCLN 1359
Query: 2003 GKQC 2006
G C
Sbjct: 1360 GGTC 1363
Score = 52.4 bits (120), Expect = 3e-05
Identities = 70/249 (28%), Positives = 90/249 (36%), Gaps = 42/249 (16%)
Query: 1315 SPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
+P G CR+++ + + G CD + + E E N CK G C+ CR
Sbjct: 723 NPCVHGACRDSLNGYKCDCDPGWSGTNCD-INNNECESNPCVNGGTCKDMTSGYVCT-CR 780
Query: 1375 TGYYGFPNCR---------PCHCPSTAICDDNGM-CICPKNVEGENCD----RCKPYTF- 1419
G+ G PNC+ PC T I D G C C G C+ C P
Sbjct: 781 EGFSG-PNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 1420 NFDVQRGCDD-----CNCNPLGVVGNQLQCEADSGKCA---CR-----ENVRGRVCDHCV 1466
N R +D C C P G G CE D +C CR +N G HC
Sbjct: 840 NGGECRQSEDYESFSCVC-PTGWQGQT--CEVDINECVLSPCRHGASCQNTHGGYRCHCQ 896
Query: 1467 PGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQD 1520
G+ DC C+ G+ D NTA C C RG C+ E +
Sbjct: 897 AGYSGRNCETDIDDCRPNPCHNGGSCTDGI--NTAFCDCLPGFRGTFCEEDINECASDPC 954
Query: 1521 DNPDGCTKC 1529
N CT C
Sbjct: 955 RNGANCTDC 963
Score = 51.6 bits (118), Expect = 5e-05
Identities = 86/351 (24%), Positives = 117/351 (33%), Gaps = 65/351 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
+C CPR +G+ CE + C P S +C N G C++ +G +
Sbjct: 1206 KCSCPRGTQGVHCEINVDD--------CNPPVDPVSRSPKC-FNNGTCVD----QVGGYS 1252
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G+ G+ G +CL C N C N C C+ G+ G RCE
Sbjct: 1253 CTCPPGFVGERCEGDVNECLSNPCDARGTQN-----CVQRVND--FHCECRAGHTGRRCE 1305
Query: 1854 YCAAGYYGIP--------EDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLK---C 1901
G G P ++ G CK P G D +C S+ CL C
Sbjct: 1306 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR--CLNGGTC 1363
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKNCTACICDE--FGMADCDSTTGT----CVCRPGVIG 1955
++ C LC F G + C+ + C+ T+ + C+C G
Sbjct: 1364 ISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 1422
Query: 1956 EKCDRCAPDHWGLNTGLGCTP-----------CN-------CGIASESTQCDDDNGQCRC 1997
C +G G P C C + + C D G C
Sbjct: 1423 LLC-HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSL 1481
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDG-CD-HCNCNTGYSVGFMC-NATGQCECL 2045
K C Q + W Y DG CD CN GF C A GQC L
Sbjct: 1482 NFNDPWKNCTQ-SLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPL 1531
Score = 50.0 bits (114), Expect = 2e-04
Identities = 86/350 (24%), Positives = 123/350 (35%), Gaps = 51/350 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVPCQCNGHSDQCDVN-TGICLNCADNTIG 1790
EC C + G +CE+ + G+ G CV N ++ +C TG C ++
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGACVD-GVNTYNCRCPPEWTG--QYCTEDV-- 296
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
D C+ + T C C + D SEN + C + GA
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGE------DCSEN--IDDCASAACFHGA 348
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAA 1909
C A +Y E TG C N + NP + GS CD+ N G A
Sbjct: 349 TCHDRVASFYC--ECPHGRTGLLCH-LNDACISNPCNEGSNCDT---------NPVNGKA 396
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C G+ G A S++ C G C+ G C+ G +C +C + G
Sbjct: 397 ICTCPSGYTGPAC-SQDVDEC---SLGANPCEHA-GKCINTLGSF--EC-QCLQGYTGPR 448
Query: 1970 TGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQC----DQCAAGFWNYTKDGCD- 2022
+ C C D G QC C G G C D+CA+ + D
Sbjct: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
Query: 2023 ----HCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEG 2067
C C TG++ G +C +C P G KC P + + EG
Sbjct: 509 INEFQCECPTGFT-GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEG 557
Score = 47.6 bits (108), Expect = 8e-04
Identities = 63/237 (26%), Positives = 86/237 (36%), Gaps = 41/237 (17%)
Query: 1877 CNCSGN-INP--QDPGSCDSI---NGDCLKCVNN--TAGAACNLCAPGFYGDAIFSKNCT 1928
C C G + P QDP C S N V+ A AC+ CA GF G +
Sbjct: 46 CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACS-CALGFSGPLCLTPLDN 104
Query: 1929 ACI---CDEFGMADCDSTTG-TCVCRPGVIGEKC---DRCAPDHWGLNTGLGCTP----- 1976
AC+ C G D + T C C PG G+ C D CA + G C P
Sbjct: 105 ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA--NGGQCLPFEASY 162
Query: 1977 -CNCGIASESTQCDDDNGQCRCAKGVT--GKQCDQCAAGFW-----NYTKDGCDH----C 2024
C+C + C D +C G+ G C + +T C+ C
Sbjct: 163 ICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC 222
Query: 2025 N---CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C G + + T +C CLPG G+ C+ E P C +C D +
Sbjct: 223 SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE---ENIDDCPGNNCKNGGACVDGV 276
Score = 45.2 bits (102), Expect = 0.005
Identities = 50/197 (25%), Positives = 67/197 (34%), Gaps = 28/197 (14%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-----CDDNGMCICPKNVEGEN 1410
GG C PN +C G + N C+ P + C +NG C+ V G +
Sbjct: 1195 GGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV--DQVGGYS 1252
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQC--EADSGKCACRENVRGRVCDHCVPG 1468
C C P + ++C NP G Q C + C CR GR C+ + G
Sbjct: 1253 CT-CPPGFVGERCEGDVNECLSNPCDARGTQ-NCVQRVNDFHCECRAGHTGRRCESVING 1310
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQ---CYCKTNVRGQACDTCKEEYFNLQDDNPDG 1525
C C GT NTA+ C C G C+ +L+ N
Sbjct: 1311 ------CKGKPCKNGGTC--AVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1362
Query: 1526 CTK------CFCFGKTT 1536
C C C G T
Sbjct: 1363 CISGPRSPTCLCLGPFT 1379
Score = 44.0 bits (99), Expect = 0.010
Identities = 59/265 (22%), Positives = 87/265 (32%), Gaps = 55/265 (20%)
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C C GF GP C L + C+ C G+ + KC C + G
Sbjct: 87 CSCALGFSGPLCLTPL----------DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
C Q P C S C +G + + +CHC +F G TCR+
Sbjct: 137 SCQQADP-------CASNPC-ANGGQCLPFEASYICHCPPSFHG---PTCRQD------V 179
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
EC P G+ C + C C+ G C + Y P C C
Sbjct: 180 NECGQKP-GLCRHGGTCHNEVGSYRCVCRATHTGPNCE---------RPYVP--CSPSPC 227
Query: 696 NLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSID 755
GT G + +C C + C++ +D C +C GG+
Sbjct: 228 QNGGTCRPTG---DVTHECACLPGFTGQNCEENID-----------DCPGNNCKNGGACV 273
Query: 756 NNCDKTTGQCHCHSRVEGRRCDQPI 780
+ + T C C G+ C + +
Sbjct: 274 DGVN--TYNCRCPPEWTGQYCTEDV 296
Score = 43.6 bits (98), Expect = 0.014
Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 27/187 (14%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRP--CHCP 1389
C C G T C +C P G TC+ C GY+G NC C
Sbjct: 1131 CRCQ-AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGV-NCSEEIDECL 1188
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
S C + G C+ N +C R T + DDCN P+ V +C ++G
Sbjct: 1189 SHP-CQNGGTCLDLPNTYKCSCPRG---TQGVHCEINVDDCN-PPVDPVSRSPKC-FNNG 1242
Query: 1450 KCACRENVRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
C + V G C C PG +C C+ GT V N C C+
Sbjct: 1243 TCV--DQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1299
Query: 1504 RGQACDT 1510
G+ C++
Sbjct: 1300 TGRRCES 1306
Score = 41.5 bits (93), Expect = 0.056
Identities = 69/286 (24%), Positives = 92/286 (32%), Gaps = 44/286 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C Y G++C + + PCQ NG + NT C +C T G HCE
Sbjct: 1169 CKCVAGYHGVNCSE------EIDECLSHPCQ-NGGTCLDLPNTYKC-SCPRGTQGVHCEI 1220
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
+ DC P+ F + + G SC C PG+ G RCE
Sbjct: 1221 NVD------------DCNPPVDPVSRSPKCFNNGTCVDQVGGY-SCTCPPGFVGERCEGD 1267
Query: 1856 AAGYYGIPEDTD------LHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCLKCV 1902
P D D+ C C IN C + G C
Sbjct: 1268 VNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN-GGTCAVAS 1326
Query: 1903 NNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDR 1960
N G C C GF G ++ C + C G + TC+C G +C
Sbjct: 1327 NTARGFICK-CPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF 1385
Query: 1961 CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC 2006
A + LG PC E T + +C C G C
Sbjct: 1386 PAS-----SPCLGGNPCYNQGTCEPTS-ESPFYRCLCPAKFNGLLC 1425
Score = 41.1 bits (92), Expect = 0.073
Identities = 51/183 (27%), Positives = 63/183 (34%), Gaps = 35/183 (19%)
Query: 1361 CKPNVIGRTCSACRTGYYG------FPNC--RPCHCPSTAICDDNG-MCICPKNVEGENC 1411
CK V TC CR GY G C +PC T DN +C C K G NC
Sbjct: 580 CKDGVATFTC-LCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Query: 1412 DRCKPYTFNFDVQRG-CDD------CNCNPLGVVGNQLQCEADSGKCA---------CRE 1455
+ + G C D C C P G G+ C + +CA C +
Sbjct: 639 EINLDDCASSPCDSGTCLDKIDGYECACEP-GYTGS--MCNINIDECAGNPCHNGGTCED 695
Query: 1456 NVRGRVCDHCVPGHYAFPDCYQ--CTCNRHGTTYDVC--DQNTAQCYCKTNVRGQACDTC 1511
+ G C C P Y P C CN + + C N +C C G CD
Sbjct: 696 GINGFTC-RC-PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN 753
Query: 1512 KEE 1514
E
Sbjct: 754 NNE 756
Score = 39.9 bits (89), Expect = 0.17
Identities = 53/210 (25%), Positives = 69/210 (32%), Gaps = 29/210 (13%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
RP C GS NT C C P G C P +C C D+
Sbjct: 912 RPNPCHNGGSCTDGINT--AFCDCLPGFRGTFCEEDINECASDPCRNGANCTD---CVDS 966
Query: 1398 GMCICPKNVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQCEADSG 1449
C CP G +C+ P G C D C C P G G+ C+ D
Sbjct: 967 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPP-GFTGS--YCQHDVN 1023
Query: 1450 KCACRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C + + G C D C Y+CTC + G T C C G C
Sbjct: 1024 ECDSQPCLHGGTCQDGC--------GSYRCTCPQ-GYTGPNCQNLVHWCDSSPCKNGGKC 1074
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRC 1538
+Y + + P G T +C + C
Sbjct: 1075 WQTHTQY---RCECPSGWTGLYCDVPSVSC 1101
Score = 39.9 bits (89), Expect = 0.17
Identities = 61/256 (23%), Positives = 85/256 (33%), Gaps = 31/256 (12%)
Query: 1299 YTREFIEQCASYNYYISPNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTF-G 1356
+ E I +CAS P G C + + S T +G C+ E + F G
Sbjct: 941 FCEEDINECAS-----DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG 995
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCH---CPSTAICDD---NGMCICPKNVEGEN 1410
G C N C TG Y + C C C D + C CP+ G N
Sbjct: 996 GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN 1055
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGV---VGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C ++ CD C G Q +CE SG +V C+ V
Sbjct: 1056 CQ---------NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE--VA 1104
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
D + C G D NT C C+ G C+ +E N CT
Sbjct: 1105 AQRQGVDVARL-CQHGGLCVDA--GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCT 1161
Query: 1528 KCFCFGKTTRCSSSYY 1543
+ G + +C + Y+
Sbjct: 1162 D-YLGGYSCKCVAGYH 1176
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 93.9 bits (223), Expect = 1e-17
Identities = 155/638 (24%), Positives = 219/638 (34%), Gaps = 107/638 (16%)
Query: 211 DPTVTRRYFYSIKDISIGGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCN 266
DPT + + G C NG+ C+P N +I C+ N C G C
Sbjct: 222 DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCK 281
Query: 267 KCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCL 326
SG+ + + FS NC + EC +P +++ D+ G KC
Sbjct: 282 DMTSGY------VCTCREGFSGP--NCQTNINECASNPCLNQGTCIDDV-----AGYKC- 327
Query: 327 NCQHNTEGINCN----KCRPTYYRPYGK-RWDELDVCQPCQCDPHFSTGNCEEESGRCEC 381
NC G C C P+ R G+ R E C C + CE + C
Sbjct: 328 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVL 387
Query: 382 RPEFQPPDCSS--------CAYGYF------DYPNCKPCTCNLNGTEGEHCTP--TDGLC 425
P C + C GY D +C+P C+ G+ CT C
Sbjct: 388 SPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS----CTDGINTAFC 443
Query: 426 PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQ 485
C + G CE ED EC + C + + D T CTC + +SG C
Sbjct: 444 DCLPGFRGTFCE--ED---INECASDPCRNGANCTDCVDSYT--CTCPAGFSGIHCEN-- 494
Query: 486 AGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGRERQ 544
N P C +C GT D ++ C+C GF G C ++ Q
Sbjct: 495 ----NTPDCTESSCFNGGT---CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGT 547
Query: 545 CVP------CNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQ--------CSPGYYK-YP 588
C C C P G T +C + C+ G +C Q C G+ Y
Sbjct: 548 CQDGCGSYRCTC-PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 606
Query: 589 DCLSCNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP- 642
D S +C+V+ + C GLC N +C Y +EC+ P
Sbjct: 607 DVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPC 666
Query: 643 -RGVTAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G T + + G C V C + + + + C+ L N + C C
Sbjct: 667 QNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS-CPRGT 725
Query: 698 AGTLNSLGA--CN------TKSGQC----VCKQHVGERQCDQCLDGFYRLQTN-DVFGCT 744
G + CN ++S +C C VG C C GF + DV C
Sbjct: 726 QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT-CPPGFVGERCEGDVNECL 784
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRV--EGRRCDQPI 780
CD G+ NC + HC R GRRC+ I
Sbjct: 785 SNPCDARGT--QNCVQRVNDFHCECRAGHTGRRCESVI 820
Score = 93.1 bits (221), Expect = 2e-17
Identities = 139/570 (24%), Positives = 188/570 (32%), Gaps = 112/570 (19%)
Query: 236 HADTCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWDRF--SCEP 290
H TC+ D N +C C T GP C C+ D + +CEP
Sbjct: 126 HGGTCQDRD-----NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEP 180
Query: 291 ----CNCHNHTTECTYDPEIDEKRLSLDING---RYEGGGKCLNCQHNTEGINCNKCRPT 343
C+ + EC +P + ING R G C N N C
Sbjct: 181 GYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC--- 237
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGY------ 397
+G D L+ + C CDP +S NC+ + CE P C GY
Sbjct: 238 ---VHGACRDSLNGYK-CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE 293
Query: 398 -FDYPNCK----PCTCNLNGTEGEHCTPTDGL-CPCKYNYAGKSCEICEDGYYSPECKNC 451
F PNC+ C N +G G C C Y G +CE+ +P C
Sbjct: 294 GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEV----VLAP-CAPS 348
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
C G D + C C + + G+TC N PC S C +
Sbjct: 349 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEV----DINECVLSPCRHGAS------CQN 398
Query: 512 VSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
G +C C+AG+ G C+ + C P C GS + + C+CL
Sbjct: 399 THGGYRCHCQAGYSGRNCETDID-----------DCRPNPCHNGGSCTDGINT-AFCDCL 446
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
F G C++ +C S C +G+ + C D+ C C + F G C+
Sbjct: 447 PGFRGTFCEE------DINECASDPCR-NGANCTDCVDSYTCTCPAGFSGIHCEN----- 494
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
N P C E +C G G S C C G C +++
Sbjct: 495 -NTPDCTESSCFNGGTCVD--GINSF----TCLCPPGFTGSYC-----------QHDVNE 536
Query: 690 CEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD 749
C+ C GT C S +C C Q C N V C C
Sbjct: 537 CDSQPCLHGGTCQD--GCG--SYRCTCPQGYTGPNCQ-----------NLVHWCDSSPCK 581
Query: 750 IGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
GG T +C C S G CD P
Sbjct: 582 NGGKCWQT--HTQYRCECPSGWTGLYCDVP 609
Score = 81.4 bits (192), Expect = 6e-14
Identities = 140/573 (24%), Positives = 192/573 (33%), Gaps = 90/573 (15%)
Query: 229 GRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCNKCCSGFEQKKWRISQNWD 284
G C+ +G+ CEP NI + C N C G C +GF R + +
Sbjct: 165 GTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF---TCRCPEGYH 221
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEK-RLSLDINGRYEGGGKCLNCQHNTEGINC----NK 339
+P C + EC +P + R SL+ G KC +C G NC N+
Sbjct: 222 ----DP-TCLSEVNECNSNPCVHGACRDSLN-------GYKC-DCDPGWSGTNCDINNNE 268
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFD 399
C G ++ C C FS NC+ C P C GY
Sbjct: 269 CESNPC-VNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY-- 325
Query: 400 YPNC-KPCTCNLNGTEGEHCTPT----DGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
NC P T C P+ G C +Y SC +C G+ + + CE +
Sbjct: 326 KCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSC-VCPTGW---QGQTCEVD 381
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG 514
V C +C++ + G C+ CQAGY + + C D P+ C +
Sbjct: 382 INECVLSPC---RHGASCQNTHGGYRCH-CQAGY----SGRNCETDIDDCRPNPCHNGGS 433
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNF 572
C G CD CL G+ E C DP G+ T C C C F
Sbjct: 434 ---CTDGINTAFCD-CLPGFRGTFC--EEDINECASDPCRNGANCTDCVDSYTCTCPAGF 487
Query: 573 GGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCREQF 629
G C+ PDC +C G TC D + C C F G+ C
Sbjct: 488 SGIHCEN------NTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQ------ 531
Query: 630 YNYPACEECNCDPRGVTASFAGCGS----VPAGEL-CQCKDRVQGRICNDCKPLYWNLQE 684
++ C+ C G GCGS P G C++ V + CK Q
Sbjct: 532 HDVNECDSQPCLHGGTCQD--GCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQT 589
Query: 685 YNPFGCEQCNCNLAGTLNSLGACNTKSGQC-VCKQHVGERQCDQCLDGFYRLQTNDVFGC 743
+ + CE C G C+ S C V Q G C G + + C
Sbjct: 590 HTQYRCE-CPSGWTGLY-----CDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHC 643
Query: 744 TECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C GS C+ +C G C
Sbjct: 644 -RCQAGYTGSY---CEDLVDECSPSPCQNGATC 672
Score = 79.8 bits (188), Expect = 2e-13
Identities = 137/562 (24%), Positives = 191/562 (33%), Gaps = 109/562 (19%)
Query: 228 GGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
GG C C + TC N LV C + C KC Q + W
Sbjct: 545 GGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPC-KNGGKCWQTHTQYRCECPSGWTG 603
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
C+ + C E+ +R +D+ + GG C++ NT +C +C+ Y
Sbjct: 604 LYCDV-----PSVSC----EVAAQRQGVDVARLCQHGGLCVDAG-NTH--HC-RCQAGYT 650
Query: 346 RPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSS---------CA 394
Y + D +D C P C + C + G C+C + +CS C
Sbjct: 651 GSYCE--DLVDECSPSPCQ---NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ 705
Query: 395 YG--YFDYPNCKPCTCNLNGTEGEHCT--------PTDGL-----C----PCKYNYAGKS 435
G D PN C+C GT+G HC P D + C C G S
Sbjct: 706 NGGTCLDLPNTYKCSCP-RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYS 764
Query: 436 CEICEDGYYSPECKN----C---ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
C C G+ C+ C C+ G+ + V C C++ ++GR C G
Sbjct: 765 CT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVING- 822
Query: 489 YNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
CK C GT + G C C AGF G C+ R C
Sbjct: 823 -----CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN-----------DARTCGS 866
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN-CDVSGSIGSTCD 606
C G T S C CL F G +C + CL N C G+ T +
Sbjct: 867 LRC-LNGGTCISGPRSPTCLCLGPFTGPECQ-----FPASSPCLGGNPCYNQGTCEPTSE 920
Query: 607 DNGL-CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV--TASFAGCGSVPAGELC-- 661
C C + F+G C Y++ + P + C ++C
Sbjct: 921 SPFYRCLCPAKFNGLLCHILD---YSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 977
Query: 662 QCKDRVQGRICNDCKPLY---W-----NLQEYNPFGCEQCN--CNLAGTLNSLGACNTKS 711
QC + G DC + W +LQ + F C+ CN AG L C
Sbjct: 978 QCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAE 1037
Query: 712 GQC------VCKQHVGERQCDQ 727
GQC CK H + CDQ
Sbjct: 1038 GQCNPLYDQYCKDHFSDGHCDQ 1059
Score = 79.4 bits (187), Expect = 2e-13
Identities = 117/471 (24%), Positives = 167/471 (35%), Gaps = 76/471 (16%)
Query: 335 INCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCA 394
+N ++C + G+ D+++ Q C+C F+ C+ + C P C
Sbjct: 1 VNTDECASSPCLHNGRCLDKINEFQ-CECPTGFTGHLCQYDVDECASTPCKNGAKC---- 55
Query: 395 YGYFDYPNCKPCTCNLNGTEGEHCTPTDGLC---PCKYNYAGKSCEICEDGYYSPECKNC 451
D PN C C G G HC C PC Y C+DG + C
Sbjct: 56 ---LDGPNTYTCVCT-EGYTGTHCEVDIDECDPDPCHYGS-------CKDGVAT---FTC 101
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNY-------PTCKPC--NCDTS 502
C G + C+ +C+ + G TC Y + P C+ +C +S
Sbjct: 102 LCRP-GYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASS 160
Query: 503 GTEPSIC-DDVSG-QCICKAGFGGPRC----DQCLSGYYMQVLGRERQCV---PCNCDPT 553
+ C D + G +C C+ G+ G C D+C +G G + C C P
Sbjct: 161 PCDSGTCLDKIDGYECACEPGYTGSMCNINIDEC-AGNPCHNGGTCEDGINGFTCRC-PE 218
Query: 554 GSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCH 612
G +C ++ +CN GA C GY C+CD S G+ CD N
Sbjct: 219 GYHDPTCLSEVNECNSNPCVHGA-CRDSLNGY-------KCDCDPGWS-GTNCDINNN-E 268
Query: 613 CKSNFDGAKCDTCREQFYNYPA-CEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRI 671
C+SN TC++ Y C E P T + C S P C D V G
Sbjct: 269 CESN-PCVNGGTCKDMTSGYVCTCREGFSGPNCQT-NINECASNPCLNQGTCIDDVAGYK 326
Query: 672 CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDG 731
CN P E C C G + + +S CVC + C+
Sbjct: 327 CNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ--SEDYESFSCVCPTGWQGQTCEV---- 380
Query: 732 FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG--QCHCHSRVEGRRCDQPI 780
D+ C C G S C T G +CHC + GR C+ I
Sbjct: 381 -------DINECVLSPCRHGAS----CQNTHGGYRCHCQAGYSGRNCETDI 420
Score = 74.9 bits (176), Expect = 5e-12
Identities = 102/376 (27%), Positives = 133/376 (35%), Gaps = 47/376 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC+ G +C+ G+ GF P C + ++C N CLN C D+ G
Sbjct: 268 ECESNPCVNGGTCKDMTSGYVCTCREGFSGP-NCQTNINECASNP--CLNQGTCIDDVAG 324
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C+ Y G AT + ++ C P P N C SE+ SC C G+ G
Sbjct: 325 YKCN-CLLPYTG-ATC----EVVLAPCA-PSPCRNGG-ECRQSEDYESFSCVCPTGWQGQ 376
Query: 1851 RCEY----CAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
CE C G Y C NC +I+ P C + G C
Sbjct: 377 TCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN-GGSCT 435
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF-GMADCDSTTG--TCVCRPGVIGE 1956
+N A C+ C PGF G ++ C D A+C TC C G G
Sbjct: 436 DGINT---AFCD-CLPGFRG-TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGI 490
Query: 1957 KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNY 2016
C+ PD + G T C GI S + C C V +CD
Sbjct: 491 HCENNTPDCTESSCFNGGT-CVDGINSFTCLCPPGFTGSYCQHDVN--ECDSQPCLHGGT 547
Query: 2017 TKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSC 2074
+DGC C C GY+ N C+ P G KC W Q C EC S
Sbjct: 548 CQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC------WQTHTQYRC-ECPSG 600
Query: 2075 TDALIFSVEDLSALLA 2090
L V +S +A
Sbjct: 601 WTGLYCDVPSVSCEVA 616
Score = 72.1 bits (169), Expect = 3e-11
Identities = 82/333 (24%), Positives = 117/333 (35%), Gaps = 42/333 (12%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C+CP + G C+ Y + PC+ NG NT C+ C + G HCE
Sbjct: 25 QCECPTGFTGHLCQ------YDVDECASTPCK-NGAKCLDGPNTYTCV-CTEGYTGTHCE 76
Query: 1795 FCMSGYHGDAT-VGTPRD---CLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
+ D G+ +D C C Y ++ C+ + N C+ QP G
Sbjct: 77 VDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHH----CETNIN----ECSSQPCRHGG 128
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C+ Y TG NC N++ CDS G CL ++ G C
Sbjct: 129 TCQDRDNAYLCFCLKGT--TGP-----NCEINLDDCASSPCDS--GTCLDKID---GYEC 176
Query: 1911 NLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC----DRCAPD 1964
C PG+ G I C C G + TC C G C + C +
Sbjct: 177 -ACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSN 235
Query: 1965 ---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
H L C+C T CD +N +C V G C +G+ ++G
Sbjct: 236 PCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF 295
Query: 2022 DHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
NC T + Q C+ V G KC+
Sbjct: 296 SGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 328
Score = 68.9 bits (161), Expect = 3e-10
Identities = 117/475 (24%), Positives = 167/475 (35%), Gaps = 83/475 (17%)
Query: 254 CRCQHNTCGPQC----NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
CRCQ G C ++C Q + +SC+ C H C+ EIDE
Sbjct: 643 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCK-CVAGYHGVNCS--EEIDEC 699
Query: 310 RLSLDINGRYEGGGKCLN--------CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
++ + GG CL+ C T+G++C P D + C
Sbjct: 700 -----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV----DPVSRSPKC 750
Query: 362 QCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
F+ G C ++ G C C P F C D C C+ GT+
Sbjct: 751 -----FNNGTCVDQVGGYSCTCPPGFVGERCEG------DVNECLSNPCDARGTQNCVQR 799
Query: 420 PTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG-DCTCKSKYSG 478
D C C+ + G+ CE +G CK C G+ + + G C C + + G
Sbjct: 800 VNDFHCECRAGHTGRRCESVING-----CKGKPCKNGGTCAVASNTARGFICKCPAGFEG 854
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQV 538
TC + TC C GT I S C+C F GP C S
Sbjct: 855 ATCEN------DARTCGSLRCLNGGT--CISGPRSPTCLCLGPFTGPECQFPASS---PC 903
Query: 539 LGRERQCVPCNCDPTG-STSTSCSADGKCNCLT------NF-GGAQCDQCSPGYYKYPDC 590
LG C+PT S C K N L +F GGA D P + +
Sbjct: 904 LGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACEL 963
Query: 591 LSCNCDVSGSIGSTCDDNGLC-----HCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV 645
C D + S +N C C NF+ C + + + +CD +
Sbjct: 964 PECQEDAGNKVCSLQCNNHACGWDGGDCSLNFND-PWKNCTQSLQCWKYFSDGHCDSQ-- 1020
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY--WNLQEYNPFGCEQCNCNLA 698
+ AGC + G CQ R +G+ C PLY + ++ C+Q CN A
Sbjct: 1021 -CNSAGC--LFDGFDCQ---RAEGQ----CNPLYDQYCKDHFSDGHCDQ-GCNSA 1064
Score = 65.3 bits (152), Expect = 4e-09
Identities = 83/329 (25%), Positives = 117/329 (35%), Gaps = 55/329 (16%)
Query: 1767 CNGHSDQCDVNTGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CN + D+C N C N C D G C C GYH + +C C
Sbjct: 187 CNINIDECAGNP--CHNGGTCEDGINGFTCR-CPEGYHDPTCLSEVNECNSNPCVHG--- 240
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPC-- 1877
+C S NG C+C PG+ G C+ C + T Y C
Sbjct: 241 -----ACRDSLNG--YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE 293
Query: 1878 -----NCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAP--GFYGDAIFSKNCTAC 1930
NC NIN C +N C+++ AG CN P G + + + C
Sbjct: 294 GFSGPNCQTNINECASNPC--LNQGT--CIDDVAGYKCNCLLPYTGATCEVVLAP-CAPS 348
Query: 1931 ICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC 1988
C G D + +CVC G G+ C+ +N + +PC G + ++T
Sbjct: 349 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEV------DINECV-LSPCRHGASCQNTH- 400
Query: 1989 DDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGV 2048
+C C G +G+ C+ D C C+ G S N T C+CLPG
Sbjct: 401 --GGYRCHCQAGYSGRNCETDI--------DDCRPNPCHNGGSCTDGIN-TAFCDCLPGF 449
Query: 2049 IGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
G C+ P C C D+
Sbjct: 450 RGTFCEEDINECASDPCRNGANCTDCVDS 478
Score = 65.3 bits (152), Expect = 4e-09
Identities = 88/363 (24%), Positives = 122/363 (33%), Gaps = 66/363 (18%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCS--------SCAYGYFDYPNCKPCT--CNL 410
C C P F+ C+ + C+ +P C +C GY PNC+ C+
Sbjct: 519 CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTG-PNCQNLVHWCDS 577
Query: 411 NGTE-GEHC--TPTDGLCPCKYNYAGKSCEI----CEDGYYSPECKNCECNTVGSVSYVC 463
+ + G C T T C C + G C++ CE G +
Sbjct: 578 SPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 637
Query: 464 DKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAG 521
T C C++ Y+G C C P C T C D G C C AG
Sbjct: 638 GN-THHCRCQAGYTGSYCEDL------VDECSPSPCQNGAT----CTDYLGGYSCKCVAG 686
Query: 522 FGGPRC----DQCLS-------------GYYMQVLGRERQCVPC--NCDPTGSTSTSCSA 562
+ G C D+CLS Y R Q V C N D S
Sbjct: 687 YHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSR 746
Query: 563 DGKC----NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFD 618
KC C+ GG C C PG+ C DV+ + + CD G +C +
Sbjct: 747 SPKCFNNGTCVDQVGGYSC-TCPPGFVGE----RCEGDVNECLSNPCDARGTQNCVQRVN 801
Query: 619 GAKCDTCREQFYNYPACEE----CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-N 673
C+ CR + CE C P + A + G +C+C +G C N
Sbjct: 802 DFHCE-CRAG-HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN 859
Query: 674 DCK 676
D +
Sbjct: 860 DAR 862
Score = 60.5 bits (140), Expect = 1e-07
Identities = 89/370 (24%), Positives = 132/370 (35%), Gaps = 48/370 (12%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
+++EC + G +CE G R P G+ P C ++C+ N + C D+ G
Sbjct: 190 NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPT-CLSEVNECNSNPCVHGACRDSLNG 248
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C+ C G+ G +C C N D++ C C+ G+ G
Sbjct: 249 YKCD-CDPGWSGTNCDINNNECESNPCV------NGGTCKDMTSG---YVCTCREGFSGP 298
Query: 1851 RCEY----CAAGYYGIPEDT--DLHTGDYCK------PCNCSGNINPQDPGSCDSINGDC 1898
C+ CA+ + + T D G C C + P P C + G+C
Sbjct: 299 NCQTNINECASNPC-LNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN-GGEC 356
Query: 1899 LKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG--TCVCRPGVI 1954
+ + +C +C G+ G + C C G A C +T G C C+ G
Sbjct: 357 RQS-EDYESFSC-VCPTGWQGQTCEVDINECVLSPC-RHG-ASCQNTHGGYRCHCQAGYS 412
Query: 1955 GEKC----DRCAPD--HWG--LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC 2006
G C D C P+ H G G+ C+C T C++D +C G C
Sbjct: 413 GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC 472
Query: 2007 DQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWV-LI 2063
C + G HC NT C G C+ G+ C CP +
Sbjct: 473 TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG--TCVDGINSFTC-LCPPGFTGSY 529
Query: 2064 PQEGCLECDS 2073
Q ECDS
Sbjct: 530 CQHDVNECDS 539
Score = 56.8 bits (131), Expect = 1e-06
Identities = 83/336 (24%), Positives = 116/336 (34%), Gaps = 51/336 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFC------VPCQC-NGHSD-QCDVNTGICLNC 1784
C CP+ Y G +C+ P G C C+C +G + CDV + C
Sbjct: 557 CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 616
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFA-LSCDLSENGSLISCNC 1843
A D C HG V + C C Y + L + S + C
Sbjct: 617 AQRQGVDVARLCQ---HGGLCVDAG-NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 672
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC-DSINGDCLKCV 1902
GG C+ C AGY+G+ ++ D C C Q+ G+C D N C
Sbjct: 673 TDYLGGYSCK-CVAGYHGVNCSEEI---DECLSHPC------QNGGTCLDLPNTYKCSCP 722
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTG--TCVCRPGVIGEKCDR 1960
T G C + C F C G +C C PG +GE+C+
Sbjct: 723 RGTQGVHCEINVDDCNPPVDPVSRSPKC----FNNGTCVDQVGGYSCTCPPGFVGERCE- 777
Query: 1961 CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDG 2020
+N L PC+ Q +D C C G TG++C+ +G
Sbjct: 778 -----GDVNECLS-NPCDARGTQNCVQRVND-FHCECRAGHTGRRCESVI--------NG 822
Query: 2021 CDHCNCNTGYSVGFMCN-ATG-QCECLPGVIGEKCD 2054
C C G + N A G C+C G G C+
Sbjct: 823 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 858
Score = 54.8 bits (126), Expect = 6e-06
Identities = 77/304 (25%), Positives = 105/304 (34%), Gaps = 56/304 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHS-DQCDVNTGICLNCADNTIGDHC 1793
C+CP + GL C+ +PS C V Q G + + G+C++ A NT HC
Sbjct: 595 CECPSGWTGLYCD--------VPSVSCEVAAQRQGVDVARLCQHGGLCVD-AGNT--HHC 643
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C +GY G +C P P N A D SC C GY G C
Sbjct: 644 R-CQAGYTGSYCEDLVDEC------SPSPCQNGATCTDYLGG---YSCKCVAGYHGVNCS 693
Query: 1854 Y---------CAAG--YYGIPEDTDLHTGDYCKPCNCSGNIN----PQDPGSCDSINGDC 1898
C G +P + +C N++ P DP S +
Sbjct: 694 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 753
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGT--CVCRPGVI 1954
CV+ G +C C PGF G+ C + CD G +C C CR G
Sbjct: 754 GTCVDQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 812
Query: 1955 GEKCDRCAPDHWGL------------NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G +C+ G NT G C C E C++D C + +
Sbjct: 813 GRRCESVINGCKGKPCKNGGTCAVASNTARGFI-CKCPAGFEGATCENDARTCGSLRCLN 871
Query: 2003 GKQC 2006
G C
Sbjct: 872 GGTC 875
Score = 52.4 bits (120), Expect = 3e-05
Identities = 70/249 (28%), Positives = 90/249 (36%), Gaps = 42/249 (16%)
Query: 1315 SPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
+P G CR+++ + + G CD + + E E N CK G C+ CR
Sbjct: 235 NPCVHGACRDSLNGYKCDCDPGWSGTNCD-INNNECESNPCVNGGTCKDMTSGYVCT-CR 292
Query: 1375 TGYYGFPNCR---------PCHCPSTAICDDNGM-CICPKNVEGENCD----RCKPYTF- 1419
G+ G PNC+ PC T I D G C C G C+ C P
Sbjct: 293 EGFSG-PNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 351
Query: 1420 NFDVQRGCDD-----CNCNPLGVVGNQLQCEADSGKCA---CR-----ENVRGRVCDHCV 1466
N R +D C C P G G CE D +C CR +N G HC
Sbjct: 352 NGGECRQSEDYESFSCVC-PTGWQGQT--CEVDINECVLSPCRHGASCQNTHGGYRCHCQ 408
Query: 1467 PGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQD 1520
G+ DC C+ G+ D NTA C C RG C+ E +
Sbjct: 409 AGYSGRNCETDIDDCRPNPCHNGGSCTDGI--NTAFCDCLPGFRGTFCEEDINECASDPC 466
Query: 1521 DNPDGCTKC 1529
N CT C
Sbjct: 467 RNGANCTDC 475
Score = 51.6 bits (118), Expect = 5e-05
Identities = 86/351 (24%), Positives = 117/351 (33%), Gaps = 65/351 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
+C CPR +G+ CE + C P S +C N G C++ +G +
Sbjct: 718 KCSCPRGTQGVHCEINVDD--------CNPPVDPVSRSPKC-FNNGTCVD----QVGGYS 764
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G+ G+ G +CL C N C N C C+ G+ G RCE
Sbjct: 765 CTCPPGFVGERCEGDVNECLSNPCDARGTQN-----CVQRVND--FHCECRAGHTGRRCE 817
Query: 1854 YCAAGYYGIP--------EDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLK---C 1901
G G P ++ G CK P G D +C S+ CL C
Sbjct: 818 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR--CLNGGTC 875
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKNCTACICDE--FGMADCDSTTGT----CVCRPGVIG 1955
++ C LC F G + C+ + C+ T+ + C+C G
Sbjct: 876 ISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 934
Query: 1956 EKCDRCAPDHWGLNTGLGCTP-----------CN-------CGIASESTQCDDDNGQCRC 1997
C +G G P C C + + C D G C
Sbjct: 935 LLC-HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSL 993
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDG-CD-HCNCNTGYSVGFMC-NATGQCECL 2045
K C Q + W Y DG CD CN GF C A GQC L
Sbjct: 994 NFNDPWKNCTQ-SLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPL 1043
Score = 45.2 bits (102), Expect = 0.005
Identities = 50/197 (25%), Positives = 67/197 (34%), Gaps = 28/197 (14%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-----CDDNGMCICPKNVEGEN 1410
GG C PN +C G + N C+ P + C +NG C+ V G +
Sbjct: 707 GGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV--DQVGGYS 764
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQC--EADSGKCACRENVRGRVCDHCVPG 1468
C C P + ++C NP G Q C + C CR GR C+ + G
Sbjct: 765 CT-CPPGFVGERCEGDVNECLSNPCDARGTQ-NCVQRVNDFHCECRAGHTGRRCESVING 822
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQ---CYCKTNVRGQACDTCKEEYFNLQDDNPDG 1525
C C GT NTA+ C C G C+ +L+ N
Sbjct: 823 ------CKGKPCKNGGTC--AVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 874
Query: 1526 CTK------CFCFGKTT 1536
C C C G T
Sbjct: 875 CISGPRSPTCLCLGPFT 891
Score = 43.6 bits (98), Expect = 0.014
Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 27/187 (14%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRP--CHCP 1389
C C G T C +C P G TC+ C GY+G NC C
Sbjct: 643 CRCQ-AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGV-NCSEEIDECL 700
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
S C + G C+ N +C R T + DDCN P+ V +C ++G
Sbjct: 701 SHP-CQNGGTCLDLPNTYKCSCPRG---TQGVHCEINVDDCN-PPVDPVSRSPKC-FNNG 754
Query: 1450 KCACRENVRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
C + V G C C PG +C C+ GT V N C C+
Sbjct: 755 TCV--DQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 811
Query: 1504 RGQACDT 1510
G+ C++
Sbjct: 812 TGRRCES 818
Score = 41.5 bits (93), Expect = 0.056
Identities = 69/286 (24%), Positives = 92/286 (32%), Gaps = 44/286 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C Y G++C + + PCQ NG + NT C +C T G HCE
Sbjct: 681 CKCVAGYHGVNCSE------EIDECLSHPCQ-NGGTCLDLPNTYKC-SCPRGTQGVHCEI 732
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
+ DC P+ F + + G SC C PG+ G RCE
Sbjct: 733 NVD------------DCNPPVDPVSRSPKCFNNGTCVDQVGGY-SCTCPPGFVGERCEGD 779
Query: 1856 AAGYYGIPEDTD------LHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCLKCV 1902
P D D+ C C IN C + G C
Sbjct: 780 VNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN-GGTCAVAS 838
Query: 1903 NNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDR 1960
N G C C GF G ++ C + C G + TC+C G +C
Sbjct: 839 NTARGFICK-CPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF 897
Query: 1961 CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQC 2006
A + LG PC E T + +C C G C
Sbjct: 898 PAS-----SPCLGGNPCYNQGTCEPTS-ESPFYRCLCPAKFNGLLC 937
Score = 41.1 bits (92), Expect = 0.073
Identities = 51/183 (27%), Positives = 63/183 (34%), Gaps = 35/183 (19%)
Query: 1361 CKPNVIGRTCSACRTGYYG------FPNC--RPCHCPSTAICDDNG-MCICPKNVEGENC 1411
CK V TC CR GY G C +PC T DN +C C K G NC
Sbjct: 92 CKDGVATFTC-LCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 150
Query: 1412 DRCKPYTFNFDVQRG-CDD------CNCNPLGVVGNQLQCEADSGKCA---------CRE 1455
+ + G C D C C P G G+ C + +CA C +
Sbjct: 151 EINLDDCASSPCDSGTCLDKIDGYECACEP-GYTGS--MCNINIDECAGNPCHNGGTCED 207
Query: 1456 NVRGRVCDHCVPGHYAFPDCYQ--CTCNRHGTTYDVC--DQNTAQCYCKTNVRGQACDTC 1511
+ G C C P Y P C CN + + C N +C C G CD
Sbjct: 208 GINGFTC-RC-PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN 265
Query: 1512 KEE 1514
E
Sbjct: 266 NNE 268
Score = 39.9 bits (89), Expect = 0.17
Identities = 53/210 (25%), Positives = 69/210 (32%), Gaps = 29/210 (13%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
RP C GS NT C C P G C P +C C D+
Sbjct: 424 RPNPCHNGGSCTDGINT--AFCDCLPGFRGTFCEEDINECASDPCRNGANCTD---CVDS 478
Query: 1398 GMCICPKNVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQCEADSG 1449
C CP G +C+ P G C D C C P G G+ C+ D
Sbjct: 479 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPP-GFTGS--YCQHDVN 535
Query: 1450 KCACRENVRGRVC-DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C + + G C D C Y+CTC + G T C C G C
Sbjct: 536 ECDSQPCLHGGTCQDGC--------GSYRCTCPQ-GYTGPNCQNLVHWCDSSPCKNGGKC 586
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRC 1538
+Y + + P G T +C + C
Sbjct: 587 WQTHTQY---RCECPSGWTGLYCDVPSVSC 613
Score = 39.9 bits (89), Expect = 0.17
Identities = 61/256 (23%), Positives = 85/256 (33%), Gaps = 31/256 (12%)
Query: 1299 YTREFIEQCASYNYYISPNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTF-G 1356
+ E I +CAS P G C + + S T +G C+ E + F G
Sbjct: 453 FCEEDINECAS-----DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG 507
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCH---CPSTAICDD---NGMCICPKNVEGEN 1410
G C N C TG Y + C C C D + C CP+ G N
Sbjct: 508 GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN 567
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGV---VGNQLQCEADSGKCACRENVRGRVCDHCVP 1467
C ++ CD C G Q +CE SG +V C+ V
Sbjct: 568 CQ---------NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE--VA 616
Query: 1468 GHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
D + C G D NT C C+ G C+ +E N CT
Sbjct: 617 AQRQGVDVARL-CQHGGLCVDA--GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCT 673
Query: 1528 KCFCFGKTTRCSSSYY 1543
+ G + +C + Y+
Sbjct: 674 D-YLGGYSCKCVAGYH 688
>AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein.
Length = 744
Score = 93.5 bits (222), Expect = 1e-17
Identities = 79/273 (28%), Positives = 113/273 (41%), Gaps = 66/273 (24%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCK 614
PG+ C + G+ G +C+ HC+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCR 314
Score = 77.4 bits (182), Expect = 9e-13
Identities = 72/250 (28%), Positives = 101/250 (40%), Gaps = 46/250 (18%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGDYCKP----CNCSGN---INPQDPGS 1890
C C+PG+ GA C G Y P E H C+P C C + + P +
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA 134
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVC 1949
C +G C + A C+ C PG++ S C C C+ A C+ TG CVC
Sbjct: 135 CGP-HGRC-----DPATGVCH-CEPGWW-----SSTCRRPCQCNT-AAARCEQATGACVC 181
Query: 1950 RPGVIGEKCD---RCAPDHWGLNTG-LGCTP------CNCGIASESTQCDDDNGQCRCAK 1999
+PG G +C C ++G C P C +C +G+C C
Sbjct: 182 KPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPP 241
Query: 2000 GVTGKQCD-QCAAGFWN----YTKDGCDH---CNCNTGYSVGFMCNATG-QCE--CLPGV 2048
G G +C+ C AG ++ C H C+ +TG G QC+ CLPG
Sbjct: 242 GFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGT 301
Query: 2049 IGEKCD-RCP 2057
GE C+ +CP
Sbjct: 302 FGESCEQQCP 311
Score = 76.6 bits (180), Expect = 2e-12
Identities = 89/345 (25%), Positives = 124/345 (35%), Gaps = 78/345 (22%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+CRC+ G C+ C G Q W E C CH H +C +P +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPH-GQC--EPATGACQCQ 121
Query: 313 LDINGRYEGGGKC-LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN 371
D G +C C G C+ + G W +PCQC+ +
Sbjct: 122 AD-----RWGARCEFPCACGPHG-RCDPATGVCHCEPG--WWSSTCRRPCQCNT--AAAR 171
Query: 372 CEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
CE+ +G C C+P + CS C C+ G C G C C+
Sbjct: 172 CEQATGACVCKPGWWGRRCSF------------RCNCH-----GSPCEQDSGRCACR--- 211
Query: 432 AGKSCEICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYY 489
G++ PEC + CEC V C +G+CTC + G C C AG +
Sbjct: 212 ---------PGWWGPECQQQCEC-----VRGRCSAASGECTCPPGFRGARCELPCPAGSH 257
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQC-ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVP 547
C EP C +G C C+ G+ G +C Q CL G + + E+QC
Sbjct: 258 GVQCAHSCG-RCKHNEP--CSPDTGSCESCEPGWNGTQCQQPCLPGTFGE--SCEQQCPH 312
Query: 548 CN----CDP--------TGSTSTSCSADGKCNCLTNFGGAQCDQC 580
C C+P +GS T+ L F G C C
Sbjct: 313 CRHGEACEPDTGHCQPGSGSRDTALIVGSLVPLLLLFLGLACCAC 357
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 66.5 bits (155), Expect = 2e-09
Identities = 51/181 (28%), Positives = 66/181 (36%), Gaps = 36/181 (19%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 C 1497
C
Sbjct: 326 C 326
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 65.3 bits (152), Expect = 4e-09
Identities = 58/194 (29%), Positives = 79/194 (40%), Gaps = 31/194 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSP---CEQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCVCRPG 1952
C+ TG C+PG
Sbjct: 319 -CEPDTGH--CQPG 329
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 44.0 bits (99), Expect = 0.010
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 1735 ECQCPRAYRGLSCE-QCAEGHYRLPSGF-CVPCQCNGHSDQCDVNTGICLNCADNTIGDH 1792
EC CP +RG CE C G + + C C+ H++ C +TG C +C G
Sbjct: 236 ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK---HNEPCSPDTGSCESCEPGWNGTQ 292
Query: 1793 CEF-CMSGYHGDA 1804
C+ C+ G G++
Sbjct: 293 CQQPCLPGTFGES 305
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>AB052949-1|BAC02695.1| 337|Homo sapiens SREC-4 protein.
Length = 337
Score = 93.5 bits (222), Expect = 1e-17
Identities = 79/273 (28%), Positives = 113/273 (41%), Gaps = 66/273 (24%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCK 614
PG+ C + G+ G +C+ HC+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCR 314
Score = 77.4 bits (182), Expect = 9e-13
Identities = 72/250 (28%), Positives = 101/250 (40%), Gaps = 46/250 (18%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGDYCKP----CNCSGN---INPQDPGS 1890
C C+PG+ GA C G Y P E H C+P C C + + P +
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA 134
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVC 1949
C +G C + A C+ C PG++ S C C C+ A C+ TG CVC
Sbjct: 135 CGP-HGRC-----DPATGVCH-CEPGWW-----SSTCRRPCQCNT-AAARCEQATGACVC 181
Query: 1950 RPGVIGEKCD---RCAPDHWGLNTG-LGCTP------CNCGIASESTQCDDDNGQCRCAK 1999
+PG G +C C ++G C P C +C +G+C C
Sbjct: 182 KPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPP 241
Query: 2000 GVTGKQCD-QCAAGFWN----YTKDGCDH---CNCNTGYSVGFMCNATG-QCE--CLPGV 2048
G G +C+ C AG ++ C H C+ +TG G QC+ CLPG
Sbjct: 242 GFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGT 301
Query: 2049 IGEKCD-RCP 2057
GE C+ +CP
Sbjct: 302 FGESCEQQCP 311
Score = 76.6 bits (180), Expect = 2e-12
Identities = 82/317 (25%), Positives = 115/317 (36%), Gaps = 70/317 (22%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+CRC+ G C+ C G Q W E C CH H +C +P +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPH-GQC--EPATGACQCQ 121
Query: 313 LDINGRYEGGGKC-LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN 371
D G +C C G C+ + G W +PCQC+ +
Sbjct: 122 AD-----RWGARCEFPCACGPHG-RCDPATGVCHCEPG--WWSSTCRRPCQCNT--AAAR 171
Query: 372 CEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
CE+ +G C C+P + CS C C+ G C G C C+
Sbjct: 172 CEQATGACVCKPGWWGRRCSF------------RCNCH-----GSPCEQDSGRCACR--- 211
Query: 432 AGKSCEICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYY 489
G++ PEC + CEC V C +G+CTC + G C C AG +
Sbjct: 212 ---------PGWWGPECQQQCEC-----VRGRCSAASGECTCPPGFRGARCELPCPAGSH 257
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQC-ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVP 547
C EP C +G C C+ G+ G +C Q CL G + + E+QC
Sbjct: 258 GVQCAHSCG-RCKHNEP--CSPDTGSCESCEPGWNGTQCQQPCLPGTFGE--SCEQQCPH 312
Query: 548 CN----CDPTGSTSTSC 560
C C+P C
Sbjct: 313 CRHGEACEPDTGHCQRC 329
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 70.1 bits (164), Expect = 1e-10
Identities = 60/200 (30%), Positives = 82/200 (41%), Gaps = 30/200 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSP---CEQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCV-CRPGVIGEK 1957
C+ TG C C PG +G +
Sbjct: 319 -CEPDTGHCQRCDPGWLGPR 337
Score = 66.5 bits (155), Expect = 2e-09
Identities = 51/181 (28%), Positives = 66/181 (36%), Gaps = 36/181 (19%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 C 1497
C
Sbjct: 326 C 326
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 44.0 bits (99), Expect = 0.010
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 1735 ECQCPRAYRGLSCE-QCAEGHYRLPSGF-CVPCQCNGHSDQCDVNTGICLNCADNTIGDH 1792
EC CP +RG CE C G + + C C+ H++ C +TG C +C G
Sbjct: 236 ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK---HNEPCSPDTGSCESCEPGWNGTQ 292
Query: 1793 CEF-CMSGYHGDA 1804
C+ C+ G G++
Sbjct: 293 CQQPCLPGTFGES 305
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>AB052947-1|BAC02693.1| 342|Homo sapiens SREC-2 protein.
Length = 342
Score = 93.5 bits (222), Expect = 1e-17
Identities = 79/273 (28%), Positives = 113/273 (41%), Gaps = 66/273 (24%)
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
G C C+P F CSS G + P+C+ C C+ +G C P G C C+ + G
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADRWGAR 128
Query: 436 CEI------------------CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKY 476
CE CE G++S C+ C+CNT + C++ TG C CK +
Sbjct: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVCKPGW 185
Query: 477 SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ---CLSG 533
GR C+ CNC S C+ SG+C C+ G+ GP C Q C+ G
Sbjct: 186 WGRRCS------------FRCNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 534 YYMQVLGRERQCVP----CNCD---PTGSTSTSCS-ADGKCN----CLTNFGGAQCDQCS 581
G E C P C+ P GS C+ + G+C C + G C+ C
Sbjct: 229 RCSAASG-ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG--SCESCE 285
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCK 614
PG+ C + G+ G +C+ HC+
Sbjct: 286 PGWNGTQCQQPC---LPGTFGESCEQQ-CPHCR 314
Score = 77.4 bits (182), Expect = 9e-13
Identities = 72/250 (28%), Positives = 101/250 (40%), Gaps = 46/250 (18%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGDYCKP----CNCSGN---INPQDPGS 1890
C C+PG+ GA C G Y P E H C+P C C + + P +
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA 134
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTA-CICDEFGMADCDSTTGTCVC 1949
C +G C + A C+ C PG++ S C C C+ A C+ TG CVC
Sbjct: 135 CGP-HGRC-----DPATGVCH-CEPGWW-----SSTCRRPCQCNT-AAARCEQATGACVC 181
Query: 1950 RPGVIGEKCD---RCAPDHWGLNTG-LGCTP------CNCGIASESTQCDDDNGQCRCAK 1999
+PG G +C C ++G C P C +C +G+C C
Sbjct: 182 KPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPP 241
Query: 2000 GVTGKQCD-QCAAGFWN----YTKDGCDH---CNCNTGYSVGFMCNATG-QCE--CLPGV 2048
G G +C+ C AG ++ C H C+ +TG G QC+ CLPG
Sbjct: 242 GFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGT 301
Query: 2049 IGEKCD-RCP 2057
GE C+ +CP
Sbjct: 302 FGESCEQQCP 311
Score = 76.6 bits (180), Expect = 2e-12
Identities = 82/317 (25%), Positives = 115/317 (36%), Gaps = 70/317 (22%)
Query: 253 VCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLS 312
+CRC+ G C+ C G Q W E C CH H +C +P +
Sbjct: 74 LCRCKPGFFGAHCSSRCPG---------QYWGPDCRESCPCHPH-GQC--EPATGACQCQ 121
Query: 313 LDINGRYEGGGKC-LNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGN 371
D G +C C G C+ + G W +PCQC+ +
Sbjct: 122 AD-----RWGARCEFPCACGPHG-RCDPATGVCHCEPG--WWSSTCRRPCQCNT--AAAR 171
Query: 372 CEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNY 431
CE+ +G C C+P + CS C C+ G C G C C+
Sbjct: 172 CEQATGACVCKPGWWGRRCSF------------RCNCH-----GSPCEQDSGRCACR--- 211
Query: 432 AGKSCEICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN-QCQAGYY 489
G++ PEC + CEC V C +G+CTC + G C C AG +
Sbjct: 212 ---------PGWWGPECQQQCEC-----VRGRCSAASGECTCPPGFRGARCELPCPAGSH 257
Query: 490 NYPTCKPCNCDTSGTEPSICDDVSGQC-ICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVP 547
C EP C +G C C+ G+ G +C Q CL G + + E+QC
Sbjct: 258 GVQCAHSCG-RCKHNEP--CSPDTGSCESCEPGWNGTQCQQPCLPGTFGE--SCEQQCPH 312
Query: 548 CN----CDPTGSTSTSC 560
C C+P C
Sbjct: 313 CRHGEACEPDTGHCQRC 329
Score = 75.4 bits (177), Expect = 4e-12
Identities = 80/295 (27%), Positives = 112/295 (37%), Gaps = 67/295 (22%)
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCD-QCLSGYYMQVLGRERQC-VP-CNCDPTGSTS 557
T GT+ S D GQ +C A P + QC +G+ ++++C +P C
Sbjct: 14 TRGTQGSELDP-KGQHVCVAS--SPSAELQCCAGWRQ----KDQECTIPICEGPDACQKD 66
Query: 558 TSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGSTCDD-NGLCHCKS 615
C G C C F GA C PG Y PDC SC C G C+ G C C++
Sbjct: 67 EVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ----CEPATGACQCQA 122
Query: 616 NFDGAKCD---TCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----Q 668
+ GA+C+ C PA C+C+P G S CQC Q
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEP--------GWWSSTCRRPCQCNTAAARCEQ 174
Query: 669 GRICNDCKPLYWNLQEYNPFGCE-QCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
CKP +W + C +CNC+ G+ C SG+C C+ +C Q
Sbjct: 175 ATGACVCKPGWWGRR------CSFRCNCH--GS-----PCEQDSGRCACRPGWWGPECQQ 221
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRA 782
+C+C + C +G+C C G RC+ P A
Sbjct: 222 -----------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPCPA 254
Score = 70.1 bits (164), Expect = 1e-10
Identities = 60/200 (30%), Positives = 82/200 (41%), Gaps = 30/200 (15%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
PCQCN + +C+ TG C+ C G C F HG +D CAC +
Sbjct: 162 PCQCNTAAARCEQATGACV-CKPGWWGRRCSF-RCNCHGSP---CEQDSGRCACRPGWWG 216
Query: 1824 NNFALSCDLSE---NGSLISCNCQPGYGGARCEY-CAAGYYGIPEDTDLHTGDYCKPCNC 1879
C+ + + C C PG+ GARCE C AG +G+ C C
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGV------QCAHSCGRCKH 270
Query: 1880 SGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICDEFGMA 1938
+ +P D GSC+S C G C C PG +G++ + C C G A
Sbjct: 271 NEPCSP-DTGSCES-------CEPGWNGTQCQQPCLPGTFGESC-EQQCPHC---RHGEA 318
Query: 1939 DCDSTTGTCV-CRPGVIGEK 1957
C+ TG C C PG +G +
Sbjct: 319 -CEPDTGHCQRCDPGWLGPR 337
Score = 66.5 bits (155), Expect = 2e-09
Identities = 51/181 (28%), Positives = 66/181 (36%), Gaps = 36/181 (19%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCS-----------------ACRTGYYGF 1380
RPC C+ + C G C CKP GR CS ACR G++G
Sbjct: 161 RPCQCN---TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG- 216
Query: 1381 PNCRP-CHCPSTAICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVV 1438
P C+ C C +G C CP G C+ C + C C N
Sbjct: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNE---- 272
Query: 1439 GNQLQCEADSGKC-ACRENVRGRVCDH-CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQ 1496
C D+G C +C G C C+PG + QC RHG + C+ +T
Sbjct: 273 ----PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG---EACEPDTGH 325
Query: 1497 C 1497
C
Sbjct: 326 C 326
Score = 65.7 bits (153), Expect = 3e-09
Identities = 58/177 (32%), Positives = 73/177 (41%), Gaps = 33/177 (18%)
Query: 1901 CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTT---GTCVCRPGVIGEK 1957
CV ++ A CA D + CT IC+ D G C C+PG G
Sbjct: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAH 85
Query: 1958 C-DRCAPDHWGLNTGLGCTPCN----CGIASESTQCDDDNGQCR----CAKGVTGKQCD- 2007
C RC +WG + C PC+ C A+ + QC D R CA G G+ CD
Sbjct: 86 CSSRCPGQYWGPDCRESC-PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-CDP 143
Query: 2008 -----QCAAGFWNYTKDGCDH-CNCNTGYSVGFMC-NATGQCECLPGVIGEKCD-RC 2056
C G+W+ T C C CNT + C ATG C C PG G +C RC
Sbjct: 144 ATGVCHCEPGWWSST---CRRPCQCNTAAA---RCEQATGACVCKPGWWGRRCSFRC 194
Score = 61.3 bits (142), Expect = 6e-08
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCR-PCHCPSTAICDD-NGMCICPKNVEGENCD-- 1412
G C CKP G CS+ G Y P+CR C C C+ G C C + G C+
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1413 -RCKPYTFNFDVQRGCDDCNCNP---LGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
C P+ D G C+C P QC + +C E G C C PG
Sbjct: 133 CACGPHG-RCDPATGV--CHCEPGWWSSTCRRPCQCNTAAARC---EQATG-AC-VCKPG 184
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ ++C C HG+ C+Q++ +C C+ G C
Sbjct: 185 WWGRRCSFRCNC--HGSP---CEQDSGRCACRPGWWGPEC 219
Score = 51.6 bits (118), Expect = 5e-05
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 22/143 (15%)
Query: 1381 PNCR-PCHCPSTAICDDNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLG-- 1436
P C P C +C G+C C G +C RC + D + + C C+P G
Sbjct: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR---ESCPCHPHGQC 111
Query: 1437 -VVGNQLQCEAD--SGKC--ACRENVRGRVCD------HCVPGHYAFPDCYQCTCNRHGT 1485
QC+AD +C C GR CD HC PG ++ C CN T
Sbjct: 112 EPATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCN---T 167
Query: 1486 TYDVCDQNTAQCYCKTNVRGQAC 1508
C+Q T C CK G+ C
Sbjct: 168 AAARCEQATGACVCKPGWWGRRC 190
Score = 44.0 bits (99), Expect = 0.010
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 1735 ECQCPRAYRGLSCE-QCAEGHYRLPSGF-CVPCQCNGHSDQCDVNTGICLNCADNTIGDH 1792
EC CP +RG CE C G + + C C+ H++ C +TG C +C G
Sbjct: 236 ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK---HNEPCSPDTGSCESCEPGWNGTQ 292
Query: 1793 CEF-CMSGYHGDA 1804
C+ C+ G G++
Sbjct: 293 CQQPCLPGTFGES 305
Score = 38.7 bits (86), Expect = 0.39
Identities = 49/199 (24%), Positives = 67/199 (33%), Gaps = 25/199 (12%)
Query: 599 GSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG 658
G+ GS D G C ++ A+ C C C+ C V G
Sbjct: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPG 73
Query: 659 ELCQCKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLN-SLGACNTKSGQ--- 713
LC+CK G C+ C YW P E C C+ G + GAC ++ +
Sbjct: 74 -LCRCKPGFFGAHCSSRCPGQYWG-----PDCRESCPCHPHGQCEPATGACQCQADRWGA 127
Query: 714 -----CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTE-CDCDIGGSIDNNCDKTTGQCHC 767
C C H +CD + C C C+ + C++ TG C C
Sbjct: 128 RCEFPCACGPH---GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA---RCEQATGACVC 181
Query: 768 HSRVEGRRCDQPIRAHYFP 786
GRRC H P
Sbjct: 182 KPGWWGRRCSFRCNCHGSP 200
>AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.
Length = 4186
Score = 91.9 bits (218), Expect = 4e-17
Identities = 61/174 (35%), Positives = 79/174 (45%), Gaps = 32/174 (18%)
Query: 423 GLCP----CKYNYAGKSCEICEDGYYSPECKNC----ECNTVGSVSYVCDKLTG-DCTCK 473
G CP C+ + SC C+ GYY P C + C GS ++ G C C
Sbjct: 2023 GPCPPHADCRDLWQTFSCT-CQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCV 2081
Query: 474 SKYSGRTCN-----QCQAGYYNYPTCKPCNCDT-SGTEPSICDDVSGQCICKAGFGGPRC 527
Y G C QC G++ PTC PCNCD G +P+ C+ +GQC CK PR
Sbjct: 2082 GGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPN-CNKTNGQCHCKEFHYRPR- 2139
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQC 580
G + C+PC+C P GSTS SC+ G+C C G QC+ C
Sbjct: 2140 ------------GSD-SCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 2180
Score = 72.1 bits (169), Expect = 3e-11
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 33/175 (18%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVC--QPCQCDPHFSTGNCEEESGR-----C 379
+C+ + +C C+P YY P +D C PCQ + G+C G C
Sbjct: 2030 DCRDLWQTFSCT-CQPGYYGP-----GCVDACLLNPCQ-----NQGSCRHLPGAPHGYTC 2078
Query: 380 ECRPEFQPPDCS-----SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCK-YNYAG 433
+C + C C G++ P C PC C+++ +C T+G C CK ++Y
Sbjct: 2079 DCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRP 2138
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
+ S C C+C VGS S C +G C C+ GR CN C + +
Sbjct: 2139 RG---------SDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2184
Score = 70.1 bits (164), Expect = 1e-10
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 30/179 (16%)
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTG-----TCVCRPGVIGEKCD-----RCA 1962
C PG+YG C C G C G TC C G G C+ +C
Sbjct: 2042 CQPGYYGPGCVDA-CLLNPCQNQG--SCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCP 2098
Query: 1963 PDHWGLNTGLGCTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
WG T C PCNC + C+ NGQC C K+ G D C
Sbjct: 2099 RGWWGSPT---CGPCNCDVHKGFDPNCNKTNGQCHC------KEFHYRPRG-----SDSC 2144
Query: 2022 DHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC-LECDSCTDAL 2078
C+C S C +GQC C PG +G +C+ C + + GC + D+C +L
Sbjct: 2145 LPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSL 2203
Score = 67.7 bits (158), Expect = 7e-10
Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 39/196 (19%)
Query: 492 PTCKPCNCDTSGTEP--SICDDV--SGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCV 546
P C N SG P + C D+ + C C+ G+ GP C D CL + + C
Sbjct: 2012 PGCVVTNACASGPCPPHADCRDLWQTFSCTCQPGYYGPGCVDACL----LNPCQNQGSCR 2067
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD-----QCSPGYYKYPDCLSCNCDVSGSI 601
P G T C+C+ + G C+ QC G++ P C CNCDV
Sbjct: 2068 HLPGAPHGYT---------CDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGF 2118
Query: 602 GSTCD-DNGLCHCKS-NFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
C+ NG CHCK ++ D+C C+C P G T+ C P
Sbjct: 2119 DPNCNKTNGQCHCKEFHYRPRGSDSCL----------PCDCYPVGSTS--RSC--APHSG 2164
Query: 660 LCQCKDRVQGRICNDC 675
C C+ GR CN C
Sbjct: 2165 QCPCRPGALGRQCNSC 2180
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/168 (30%), Positives = 69/168 (41%), Gaps = 26/168 (15%)
Query: 380 ECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGE-HCTPTDGL-----CPCKYNYAG 433
+CR +Q C+ C GY+ P C C LN + + C G C C Y G
Sbjct: 2030 DCRDLWQTFSCT-CQPGYYG-PGCVDA-CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFG 2086
Query: 434 KSCEI-----CEDGYY-SPECKNCECNTVGSVSYVCDKLTGDCTCKS-KYSGRTCNQCQA 486
CE C G++ SP C C C+ C+K G C CK Y R +
Sbjct: 2087 HHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSD---- 2142
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY 534
+C PC+C G+ C SGQC C+ G G +C+ C S +
Sbjct: 2143 ------SCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2184
Score = 62.1 bits (144), Expect = 4e-08
Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 29/164 (17%)
Query: 1871 GDYCKPCNCSGNINP-QDPGSCDSI----NGDCLKCVNNTAGAACN-----LCAPGFYGD 1920
G Y C + +NP Q+ GSC + +G CV G C C G++G
Sbjct: 2045 GYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWG- 2103
Query: 1921 AIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN 1978
S C C CD D C+ T G C C+ H+ C PC+
Sbjct: 2104 ---SPTCGPCNCDVHKGFDPNCNKTNGQCHCKEF------------HYRPRGSDSCLPCD 2148
Query: 1979 C-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
C + S S C +GQC C G G+QC+ C + F T GC
Sbjct: 2149 CYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGC 2192
Score = 61.3 bits (142), Expect = 6e-08
Identities = 67/250 (26%), Positives = 87/250 (34%), Gaps = 34/250 (13%)
Query: 240 CEP-ADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTT 298
C P AD C CQ GP C C QN P H +T
Sbjct: 2025 CPPHADCRDLWQTFSCTCQPGYYGPGCVDAC------LLNPCQNQGSCRHLPGAPHGYTC 2078
Query: 299 ECT--YDPEIDEKRLSLDINGRYEGGGKC--LNCQ-HNTEGINCNK------CRPTYYRP 347
+C Y E R+ + G C NC H NCNK C+ +YRP
Sbjct: 2079 DCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRP 2138
Query: 348 YGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSC--AYGYFDYPNCK 404
G D C PC C P ST +C SG+C CRP C+SC + C+
Sbjct: 2139 RGS-----DSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCR 2193
Query: 405 PC--TCNLNGTEGEHCTPTD----GLCPCKYNYAGKSCEICED--GYYSPECKNCECNTV 456
C + G T PC G + +C++ G+ P+ NC
Sbjct: 2194 VLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALGAAVRLCDEAQGWLEPDLFNCTSPAF 2253
Query: 457 GSVSYVCDKL 466
+S + D L
Sbjct: 2254 RELSLLLDGL 2263
Score = 57.6 bits (133), Expect = 8e-07
Identities = 48/190 (25%), Positives = 67/190 (35%), Gaps = 23/190 (12%)
Query: 588 PDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
P C+ N SG D C+ + C TC+ +Y + C +P
Sbjct: 2012 PGCVVTNACASGPCPPHAD------CRDLWQTFSC-TCQPGYYGPGCVDACLLNPCQNQG 2064
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
S P G C C G C + C CNC++ + C
Sbjct: 2065 SCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDP--NC 2122
Query: 708 NTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
N +GQC CK+ YR + +D C CDC GS +C +GQC C
Sbjct: 2123 NKTNGQCHCKEF------------HYRPRGSD--SCLPCDCYPVGSTSRSCAPHSGQCPC 2168
Query: 768 HSRVEGRRCD 777
GR+C+
Sbjct: 2169 RPGALGRQCN 2178
Score = 55.6 bits (128), Expect = 3e-06
Identities = 44/142 (30%), Positives = 57/142 (40%), Gaps = 20/142 (14%)
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ 692
P N +P V + C S P C+D Q C C+P Y Y P +
Sbjct: 2003 PPSHRVNAEPGCVVTN--ACASGPCPPHADCRDLWQTFSCT-CQPGY-----YGPGCVDA 2054
Query: 693 C---NCNLAGTLNSL-GACNTKSGQCV---CKQHVGERQCDQCLDGFYRLQTNDVFGCTE 745
C C G+ L GA + + CV H R QC G++ T C
Sbjct: 2055 CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPT-----CGP 2109
Query: 746 CDCDIGGSIDNNCDKTTGQCHC 767
C+CD+ D NC+KT GQCHC
Sbjct: 2110 CNCDVHKGFDPNCNKTNGQCHC 2131
Score = 55.6 bits (128), Expect = 3e-06
Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 18/165 (10%)
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPC---NCDTSGTEPSICDDVSGQ-CICKAGFGGPRC 527
C+ + +C CQ GYY C C G+ + G C C G+ G C
Sbjct: 2031 CRDLWQTFSCT-CQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHC 2089
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLT-NFGGAQCDQCSPGYY 585
+ + + C PCNCD +C+ +G+C+C ++ D C P
Sbjct: 2090 EHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLP--- 2146
Query: 586 KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQF 629
C+C GS +C +G C C+ G +C++C F
Sbjct: 2147 -------CDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2184
Score = 52.8 bits (121), Expect = 2e-05
Identities = 49/173 (28%), Positives = 65/173 (37%), Gaps = 41/173 (23%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY+G V CL+ C N L +C+C GY G CE+
Sbjct: 2042 CQPGYYGPGCVDA---CLLNPC------QNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHR 2092
Query: 1855 ----CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C G++G P C PCNC + DP +C+ NG C C
Sbjct: 2093 MDQQCPRGWWGSPT---------CGPCNCDVH-KGFDP-NCNKTNGQC-HCKE------- 2133
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRC 1961
F+ S +C C C G C +G C CRPG +G +C+ C
Sbjct: 2134 ------FHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 2180
Score = 52.0 bits (119), Expect = 4e-05
Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 35/176 (19%)
Query: 1360 PCKPNV----IGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDNGMCI-CPKNVEGENCDR 1413
PC P+ + +T S C+ GYYG P C C C + G C P G CD
Sbjct: 2024 PCPPHADCRDLWQTFSCTCQPGYYG-PGCVDA-CLLNP-CQNQGSCRHLPGAPHGYTCDC 2080
Query: 1414 CKPY-----TFNFDVQ--RG------CDDCNCNPLGVVGNQLQCEADSGKCACRE-NVRG 1459
Y D Q RG C CNC+ G C +G+C C+E + R
Sbjct: 2081 VGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHK--GFDPNCNKTNGQCHCKEFHYRP 2138
Query: 1460 RVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
R D C+P C C G+T C ++ QC C+ G+ C++C +
Sbjct: 2139 RGSDSCLP----------CDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2184
Score = 50.4 bits (115), Expect = 1e-04
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1317 NET-GLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
N+T G C F + PC C +GST C GQCPC+P +GR C++C
Sbjct: 2123 NKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 2180
Score = 48.0 bits (109), Expect = 6e-04
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 38/195 (19%)
Query: 549 NCDPTGSTSTSCSADGKC----NCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGS 603
N +P G T+ A G C +C + C C PGYY P C+ +C + + GS
Sbjct: 2009 NAEP-GCVVTNACASGPCPPHADCRDLWQTFSCT-CQPGYYG-PGCVDACLLNPCQNQGS 2065
Query: 604 TCDDNGL-----CHCKSNFDGAKCD-----TCREQFYNYPACEECNCDPRGVTASFAGCG 653
G C C + G C+ C ++ P C CNCD V F
Sbjct: 2066 CRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCD---VHKGFDPNC 2122
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
+ G+ C CK+ ++ + C C+C G+ + +C SGQ
Sbjct: 2123 NKTNGQ-CHCKE--------------FHYRPRGSDSCLPCDCYPVGSTSR--SCAPHSGQ 2165
Query: 714 CVCKQHVGERQCDQC 728
C C+ RQC+ C
Sbjct: 2166 CPCRPGALGRQCNSC 2180
Score = 46.8 bits (106), Expect = 0.001
Identities = 58/202 (28%), Positives = 75/202 (37%), Gaps = 37/202 (18%)
Query: 1736 CQCPRAYRGLSCE-----QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
C C Y G CE QC G + P+ C PC C DV+ G NC
Sbjct: 2078 CDCVGGYFGHHCEHRMDQQCPRGWWGSPT--CGPCNC-------DVHKGFDPNCNKTNGQ 2128
Query: 1791 DHC-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
HC EF D+ CL C C YP + + SC +G C C+PG G
Sbjct: 2129 CHCKEFHYRPRGSDS-------CLPCDC---YPVGSTSRSC-APHSGQ---CPCRPGALG 2174
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
+C C + + + D C SG PQ + + C GAA
Sbjct: 2175 RQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLA----TVPCPRGALGAA 2230
Query: 1910 CNLC--APGFYGDAIFSKNCTA 1929
LC A G+ +F NCT+
Sbjct: 2231 VRLCDEAQGWLEPDLF--NCTS 2250
Score = 44.0 bits (99), Expect = 0.010
Identities = 35/113 (30%), Positives = 45/113 (39%), Gaps = 14/113 (12%)
Query: 1906 AGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
AG C C PGF GD ++ C + C G TCVCRP GE C+
Sbjct: 1487 AGLRCR-CPPGFTGDFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCE---- 1541
Query: 1964 DHWGLNTGLG-CTPCNCGIASESTQCDDDNGQCRCAKG--VTGKQCDQCAAGF 2013
L+T G C P C T + +C+C G G +C+ A F
Sbjct: 1542 ----LDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAFEGPRCEVAARSF 1590
Score = 40.7 bits (91), Expect = 0.097
Identities = 37/118 (31%), Positives = 47/118 (39%), Gaps = 27/118 (22%)
Query: 420 PTDGL-CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG--DCTCKSKY 476
P GL C C + G CE D YS C+N C + G C C+ ++
Sbjct: 1485 PIAGLRCRCPPGFTGDFCETELDLCYSNPCRN---------GGACARREGGYTCVCRPRF 1535
Query: 477 SGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG---QCICKAG--FGGPRCD 528
+G C +AG C P C GT C D +C C AG F GPRC+
Sbjct: 1536 TGEDCELDTEAG-----RCVPGVCRNGGT----CTDAPNGGFRCQCPAGGAFEGPRCE 1584
Score = 38.3 bits (85), Expect = 0.52
Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 6/77 (7%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKP-NVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
PC CD + CN GQC CK + R +C +C P S + +
Sbjct: 2109 PCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLP-----CDCYPVGSTSRSCAPHS 2163
Query: 1398 GMCICPKNVEGENCDRC 1414
G C C G C+ C
Sbjct: 2164 GQCPCRPGALGRQCNSC 2180
Score = 36.7 bits (81), Expect = 1.6
Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 21/112 (18%)
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEFQPPDCS 391
G+ C +C P + + + ELD+C C + G C G C CRP F DC
Sbjct: 1488 GLRC-RCPPGFTGDFCET--ELDLCYSNPCR---NGGACARREGGYTCVCRPRFTGEDCE 1541
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCT--PTDGL---CPCKYNYAGKSCEI 438
+ C P C GT CT P G CP + G CE+
Sbjct: 1542 LDT----EAGRCVPGVCRNGGT----CTDAPNGGFRCQCPAGGAFEGPRCEV 1585
>AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo 1
protein.
Length = 3312
Score = 91.9 bits (218), Expect = 4e-17
Identities = 61/174 (35%), Positives = 79/174 (45%), Gaps = 32/174 (18%)
Query: 423 GLCP----CKYNYAGKSCEICEDGYYSPECKNC----ECNTVGSVSYVCDKLTG-DCTCK 473
G CP C+ + SC C+ GYY P C + C GS ++ G C C
Sbjct: 1953 GPCPPHADCRDLWQTFSCT-CQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCV 2011
Query: 474 SKYSGRTCN-----QCQAGYYNYPTCKPCNCDT-SGTEPSICDDVSGQCICKAGFGGPRC 527
Y G C QC G++ PTC PCNCD G +P+ C+ +GQC CK PR
Sbjct: 2012 GGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPN-CNKTNGQCHCKEFHYRPR- 2069
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQC 580
G + C+PC+C P GSTS SC+ G+C C G QC+ C
Sbjct: 2070 ------------GSD-SCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 2110
Score = 72.1 bits (169), Expect = 3e-11
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 33/175 (18%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVC--QPCQCDPHFSTGNCEEESGR-----C 379
+C+ + +C C+P YY P +D C PCQ + G+C G C
Sbjct: 1960 DCRDLWQTFSCT-CQPGYYGP-----GCVDACLLNPCQ-----NQGSCRHLPGAPHGYTC 2008
Query: 380 ECRPEFQPPDCS-----SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCK-YNYAG 433
+C + C C G++ P C PC C+++ +C T+G C CK ++Y
Sbjct: 2009 DCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRP 2068
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
+ S C C+C VGS S C +G C C+ GR CN C + +
Sbjct: 2069 RG---------SDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2114
Score = 70.1 bits (164), Expect = 1e-10
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 30/179 (16%)
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTG-----TCVCRPGVIGEKCD-----RCA 1962
C PG+YG C C G C G TC C G G C+ +C
Sbjct: 1972 CQPGYYGPGCVDA-CLLNPCQNQG--SCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCP 2028
Query: 1963 PDHWGLNTGLGCTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
WG T C PCNC + C+ NGQC C K+ G D C
Sbjct: 2029 RGWWGSPT---CGPCNCDVHKGFDPNCNKTNGQCHC------KEFHYRPRG-----SDSC 2074
Query: 2022 DHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC-LECDSCTDAL 2078
C+C S C +GQC C PG +G +C+ C + + GC + D+C +L
Sbjct: 2075 LPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSL 2133
Score = 67.7 bits (158), Expect = 7e-10
Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 39/196 (19%)
Query: 492 PTCKPCNCDTSGTEP--SICDDV--SGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCV 546
P C N SG P + C D+ + C C+ G+ GP C D CL + + C
Sbjct: 1942 PGCVVTNACASGPCPPHADCRDLWQTFSCTCQPGYYGPGCVDACL----LNPCQNQGSCR 1997
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD-----QCSPGYYKYPDCLSCNCDVSGSI 601
P G T C+C+ + G C+ QC G++ P C CNCDV
Sbjct: 1998 HLPGAPHGYT---------CDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGF 2048
Query: 602 GSTCD-DNGLCHCKS-NFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
C+ NG CHCK ++ D+C C+C P G T+ C P
Sbjct: 2049 DPNCNKTNGQCHCKEFHYRPRGSDSCL----------PCDCYPVGSTS--RSC--APHSG 2094
Query: 660 LCQCKDRVQGRICNDC 675
C C+ GR CN C
Sbjct: 2095 QCPCRPGALGRQCNSC 2110
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/168 (30%), Positives = 69/168 (41%), Gaps = 26/168 (15%)
Query: 380 ECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGE-HCTPTDGL-----CPCKYNYAG 433
+CR +Q C+ C GY+ P C C LN + + C G C C Y G
Sbjct: 1960 DCRDLWQTFSCT-CQPGYYG-PGCVDA-CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFG 2016
Query: 434 KSCEI-----CEDGYY-SPECKNCECNTVGSVSYVCDKLTGDCTCKS-KYSGRTCNQCQA 486
CE C G++ SP C C C+ C+K G C CK Y R +
Sbjct: 2017 HHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSD---- 2072
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY 534
+C PC+C G+ C SGQC C+ G G +C+ C S +
Sbjct: 2073 ------SCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2114
Score = 62.1 bits (144), Expect = 4e-08
Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 29/164 (17%)
Query: 1871 GDYCKPCNCSGNINP-QDPGSCDSI----NGDCLKCVNNTAGAACN-----LCAPGFYGD 1920
G Y C + +NP Q+ GSC + +G CV G C C G++G
Sbjct: 1975 GYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWG- 2033
Query: 1921 AIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN 1978
S C C CD D C+ T G C C+ H+ C PC+
Sbjct: 2034 ---SPTCGPCNCDVHKGFDPNCNKTNGQCHCKEF------------HYRPRGSDSCLPCD 2078
Query: 1979 C-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
C + S S C +GQC C G G+QC+ C + F T GC
Sbjct: 2079 CYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGC 2122
Score = 61.3 bits (142), Expect = 6e-08
Identities = 67/250 (26%), Positives = 87/250 (34%), Gaps = 34/250 (13%)
Query: 240 CEP-ADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTT 298
C P AD C CQ GP C C QN P H +T
Sbjct: 1955 CPPHADCRDLWQTFSCTCQPGYYGPGCVDAC------LLNPCQNQGSCRHLPGAPHGYTC 2008
Query: 299 ECT--YDPEIDEKRLSLDINGRYEGGGKC--LNCQ-HNTEGINCNK------CRPTYYRP 347
+C Y E R+ + G C NC H NCNK C+ +YRP
Sbjct: 2009 DCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRP 2068
Query: 348 YGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSC--AYGYFDYPNCK 404
G D C PC C P ST +C SG+C CRP C+SC + C+
Sbjct: 2069 RGS-----DSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCR 2123
Query: 405 PC--TCNLNGTEGEHCTPTD----GLCPCKYNYAGKSCEICED--GYYSPECKNCECNTV 456
C + G T PC G + +C++ G+ P+ NC
Sbjct: 2124 VLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALGAAVRLCDEAQGWLEPDLFNCTSPAF 2183
Query: 457 GSVSYVCDKL 466
+S + D L
Sbjct: 2184 RELSLLLDGL 2193
Score = 57.6 bits (133), Expect = 8e-07
Identities = 48/190 (25%), Positives = 67/190 (35%), Gaps = 23/190 (12%)
Query: 588 PDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
P C+ N SG D C+ + C TC+ +Y + C +P
Sbjct: 1942 PGCVVTNACASGPCPPHAD------CRDLWQTFSC-TCQPGYYGPGCVDACLLNPCQNQG 1994
Query: 648 SFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
S P G C C G C + C CNC++ + C
Sbjct: 1995 SCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDP--NC 2052
Query: 708 NTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
N +GQC CK+ YR + +D C CDC GS +C +GQC C
Sbjct: 2053 NKTNGQCHCKEF------------HYRPRGSD--SCLPCDCYPVGSTSRSCAPHSGQCPC 2098
Query: 768 HSRVEGRRCD 777
GR+C+
Sbjct: 2099 RPGALGRQCN 2108
Score = 55.6 bits (128), Expect = 3e-06
Identities = 44/142 (30%), Positives = 57/142 (40%), Gaps = 20/142 (14%)
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ 692
P N +P V + C S P C+D Q C C+P Y Y P +
Sbjct: 1933 PPSHRVNAEPGCVVTN--ACASGPCPPHADCRDLWQTFSCT-CQPGY-----YGPGCVDA 1984
Query: 693 C---NCNLAGTLNSL-GACNTKSGQCV---CKQHVGERQCDQCLDGFYRLQTNDVFGCTE 745
C C G+ L GA + + CV H R QC G++ T C
Sbjct: 1985 CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPT-----CGP 2039
Query: 746 CDCDIGGSIDNNCDKTTGQCHC 767
C+CD+ D NC+KT GQCHC
Sbjct: 2040 CNCDVHKGFDPNCNKTNGQCHC 2061
Score = 55.6 bits (128), Expect = 3e-06
Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 18/165 (10%)
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPC---NCDTSGTEPSICDDVSGQ-CICKAGFGGPRC 527
C+ + +C CQ GYY C C G+ + G C C G+ G C
Sbjct: 1961 CRDLWQTFSCT-CQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHC 2019
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLT-NFGGAQCDQCSPGYY 585
+ + + C PCNCD +C+ +G+C+C ++ D C P
Sbjct: 2020 EHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLP--- 2076
Query: 586 KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQF 629
C+C GS +C +G C C+ G +C++C F
Sbjct: 2077 -------CDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2114
Score = 52.8 bits (121), Expect = 2e-05
Identities = 49/173 (28%), Positives = 65/173 (37%), Gaps = 41/173 (23%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY+G V CL+ C N L +C+C GY G CE+
Sbjct: 1972 CQPGYYGPGCVDA---CLLNPC------QNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHR 2022
Query: 1855 ----CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C G++G P C PCNC + DP +C+ NG C C
Sbjct: 2023 MDQQCPRGWWGSPT---------CGPCNCDVH-KGFDP-NCNKTNGQC-HCKE------- 2063
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRC 1961
F+ S +C C C G C +G C CRPG +G +C+ C
Sbjct: 2064 ------FHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 2110
Score = 52.0 bits (119), Expect = 4e-05
Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 35/176 (19%)
Query: 1360 PCKPNV----IGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDNGMCI-CPKNVEGENCDR 1413
PC P+ + +T S C+ GYYG P C C C + G C P G CD
Sbjct: 1954 PCPPHADCRDLWQTFSCTCQPGYYG-PGCVDA-CLLNP-CQNQGSCRHLPGAPHGYTCDC 2010
Query: 1414 CKPY-----TFNFDVQ--RG------CDDCNCNPLGVVGNQLQCEADSGKCACRE-NVRG 1459
Y D Q RG C CNC+ G C +G+C C+E + R
Sbjct: 2011 VGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHK--GFDPNCNKTNGQCHCKEFHYRP 2068
Query: 1460 RVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
R D C+P C C G+T C ++ QC C+ G+ C++C +
Sbjct: 2069 RGSDSCLP----------CDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 2114
Score = 50.4 bits (115), Expect = 1e-04
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1317 NET-GLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
N+T G C F + PC C +GST C GQCPC+P +GR C++C
Sbjct: 2053 NKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 2110
Score = 48.0 bits (109), Expect = 6e-04
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 38/195 (19%)
Query: 549 NCDPTGSTSTSCSADGKC----NCLTNFGGAQCDQCSPGYYKYPDCL-SCNCDVSGSIGS 603
N +P G T+ A G C +C + C C PGYY P C+ +C + + GS
Sbjct: 1939 NAEP-GCVVTNACASGPCPPHADCRDLWQTFSCT-CQPGYYG-PGCVDACLLNPCQNQGS 1995
Query: 604 TCDDNGL-----CHCKSNFDGAKCD-----TCREQFYNYPACEECNCDPRGVTASFAGCG 653
G C C + G C+ C ++ P C CNCD V F
Sbjct: 1996 CRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCD---VHKGFDPNC 2052
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQ 713
+ G+ C CK+ ++ + C C+C G+ + +C SGQ
Sbjct: 2053 NKTNGQ-CHCKE--------------FHYRPRGSDSCLPCDCYPVGSTSR--SCAPHSGQ 2095
Query: 714 CVCKQHVGERQCDQC 728
C C+ RQC+ C
Sbjct: 2096 CPCRPGALGRQCNSC 2110
Score = 46.8 bits (106), Expect = 0.001
Identities = 58/202 (28%), Positives = 75/202 (37%), Gaps = 37/202 (18%)
Query: 1736 CQCPRAYRGLSCE-----QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
C C Y G CE QC G + P+ C PC C DV+ G NC
Sbjct: 2008 CDCVGGYFGHHCEHRMDQQCPRGWWGSPT--CGPCNC-------DVHKGFDPNCNKTNGQ 2058
Query: 1791 DHC-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
HC EF D+ CL C C YP + + SC +G C C+PG G
Sbjct: 2059 CHCKEFHYRPRGSDS-------CLPCDC---YPVGSTSRSC-APHSGQ---CPCRPGALG 2104
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAA 1909
+C C + + + D C SG PQ + + C GAA
Sbjct: 2105 RQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLA----TVPCPRGALGAA 2160
Query: 1910 CNLC--APGFYGDAIFSKNCTA 1929
LC A G+ +F NCT+
Sbjct: 2161 VRLCDEAQGWLEPDLF--NCTS 2180
Score = 44.0 bits (99), Expect = 0.010
Identities = 35/113 (30%), Positives = 45/113 (39%), Gaps = 14/113 (12%)
Query: 1906 AGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAP 1963
AG C C PGF GD ++ C + C G TCVCRP GE C+
Sbjct: 1417 AGLRCR-CPPGFTGDFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCE---- 1471
Query: 1964 DHWGLNTGLG-CTPCNCGIASESTQCDDDNGQCRCAKG--VTGKQCDQCAAGF 2013
L+T G C P C T + +C+C G G +C+ A F
Sbjct: 1472 ----LDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAFEGPRCEVAARSF 1520
Score = 40.7 bits (91), Expect = 0.097
Identities = 37/118 (31%), Positives = 47/118 (39%), Gaps = 27/118 (22%)
Query: 420 PTDGL-CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG--DCTCKSKY 476
P GL C C + G CE D YS C+N C + G C C+ ++
Sbjct: 1415 PIAGLRCRCPPGFTGDFCETELDLCYSNPCRN---------GGACARREGGYTCVCRPRF 1465
Query: 477 SGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG---QCICKAG--FGGPRCD 528
+G C +AG C P C GT C D +C C AG F GPRC+
Sbjct: 1466 TGEDCELDTEAG-----RCVPGVCRNGGT----CTDAPNGGFRCQCPAGGAFEGPRCE 1514
Score = 38.3 bits (85), Expect = 0.52
Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 6/77 (7%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKP-NVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
PC CD + CN GQC CK + R +C +C P S + +
Sbjct: 2039 PCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLP-----CDCYPVGSTSRSCAPHS 2093
Query: 1398 GMCICPKNVEGENCDRC 1414
G C C G C+ C
Sbjct: 2094 GQCPCRPGALGRQCNSC 2110
Score = 36.7 bits (81), Expect = 1.6
Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 21/112 (18%)
Query: 334 GINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEFQPPDCS 391
G+ C +C P + + + ELD+C C + G C G C CRP F DC
Sbjct: 1418 GLRC-RCPPGFTGDFCET--ELDLCYSNPCR---NGGACARREGGYTCVCRPRFTGEDCE 1471
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCT--PTDGL---CPCKYNYAGKSCEI 438
+ C P C GT CT P G CP + G CE+
Sbjct: 1472 LDT----EAGRCVPGVCRNGGT----CTDAPNGGFRCQCPAGGAFEGPRCEV 1515
>X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein.
Length = 2199
Score = 91.1 bits (216), Expect = 7e-17
Identities = 123/472 (26%), Positives = 175/472 (37%), Gaps = 78/472 (16%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNC--KPCTCNLNGTEGEHCTPTDGLC 425
GN E C C P ++ P+CS C C C C+ +G GE C+ C
Sbjct: 165 GNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICD-DGFTGEDCSQL--AC 221
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSY-VCDKLTGDCTCKSKYSGRTC 481
P N GK IC +G Y+ +C C S + C + G C C ++G C
Sbjct: 222 PSDCNDQGKCVNGVCICFEG-YAADCSREICPVPCSEEHGTC--VDGLCVCHDGFAGDDC 278
Query: 482 NQ--CQAGYYNYPTC--KPCNCDTSGTE--------PSICDD----VSGQCICKAGFGGP 525
N+ C YN C C CD T P+ C D ++G C C+ GF G
Sbjct: 279 NKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGE 338
Query: 526 RCDQ--CLSGYYMQVLGRERQCV------PCNCD----PTGSTSTSCSADGKCNCLTNFG 573
C + C + Q E QCV +C P + DG+C C F
Sbjct: 339 DCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFT 398
Query: 574 GAQCDQ--CSPGYYKYPDCLS--CNCDVSGSIGSTCDD---NGLCHCKSNFDGAKCDTCR 626
GA C + C G + C++ C CD G G C CH + KC C
Sbjct: 399 GADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLRCPNDCHSRGRCVEGKC-VCE 456
Query: 627 EQFYNYPACE-EC--NCDPRG-VTASFAGCGSVPAGELCQCKDRVQGRICND---CKPLY 679
+ F Y + C +C G C GE C+DR R C++ C
Sbjct: 457 QGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGE--DCRDRQCPRDCSNRGLCVDGQ 514
Query: 680 WNLQE-YNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQ-HVG----ERQCDQCLDGFY 733
++ + C + +C + G C +GQCVC + +G E++C G
Sbjct: 515 CVCEDGFTGPDCAELSC--PNDCHGQGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQG 570
Query: 734 RLQTNDVF---GCTECDCDIGGSIDNNCDK----TTGQCHCHSRVEGRRCDQ 778
R G T DC S ++C+ +G+C C+ G C +
Sbjct: 571 RCVDGQCICHEGFTGLDCG-QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 621
Score = 79.8 bits (188), Expect = 2e-13
Identities = 110/429 (25%), Positives = 157/429 (36%), Gaps = 87/429 (20%)
Query: 227 IGGRCMC-NGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDR 285
+ G C+C G+A AD + + + C +H TC C GF + ++
Sbjct: 232 VNGVCICFEGYA-----ADCSREICPVPCSEEHGTCVDGLCVCHDGFA------GDDCNK 280
Query: 286 FSCEPCNCHNH----TTECTYDPEIDEKRLSLDI--NGRYEGGGKCLN----CQHNTEGI 335
C NC+N EC D + S I N ++ G +C+N C+ G
Sbjct: 281 PLCLN-NCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRG-RCINGTCYCEEGFTGE 338
Query: 336 NCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE-------------SGRCECR 382
+C K PT P+ C CD F+ +C E+ GRCEC
Sbjct: 339 DCGK--PTC--PHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECD 394
Query: 383 PEFQPPDCSS--CAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
F DC C G + C C C+ G GE C+ CP + G+ E
Sbjct: 395 DGFTGADCGELKCPNGCSGHGRCVNGQCVCD-EGYTGEDCSQLR--CPNDCHSRGRCVEG 451
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCK 495
+CE G+ +C + C C + G C C Y+G C Q
Sbjct: 452 KCVCEQGFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRDRQC--------- 500
Query: 496 PCNCDTSGTEPSICDDVSGQCICKAGFGGPRC------------DQCLSGYYMQVLG-RE 542
P +C G +C V GQC+C+ GF GP C +C++G + G
Sbjct: 501 PRDCSNRG----LC--VDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMG 554
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ--CSPGYYKYPDCLS--CNCDVS 598
+ C C P+ DG+C C F G C Q C C+S C C+
Sbjct: 555 KDCKEQRC-PSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICN-E 612
Query: 599 GSIGSTCDD 607
G G C +
Sbjct: 613 GYSGEDCSE 621
Score = 67.7 bits (158), Expect = 7e-10
Identities = 93/349 (26%), Positives = 122/349 (34%), Gaps = 67/349 (19%)
Query: 470 CTCKSKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD 528
C+ + +S C C+ G+ P C C + C D GQCIC GF G C
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKG-PNCSEPECPGNCHLRGRCID--GQCICDDGFTGEDCS 217
Query: 529 Q------------CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQ 576
Q C++G + G C C S DG C C F G
Sbjct: 218 QLACPSDCNDQGKCVNGVCICFEGYAADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDD 277
Query: 577 CDQ--CSPGYYKYPDCL--SCNCDVSGSIGSTCDD--------------NGLCHCKSNFD 618
C++ C Y C+ C CD G G C + NG C+C+ F
Sbjct: 278 CNKPLCLNNCYNRGRCVENECVCD-EGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFT 336
Query: 619 GAKC--DTCREQFYNYPACEE--CNCDP--RGVTASFAGCGSVPAGELCQCKDR-VQGRI 671
G C TC + CEE C CD GV S C PA C + R V GR
Sbjct: 337 GEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC---PAD--CHNRGRCVDGRC 391
Query: 672 -CNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ--C 728
C+D + C + C + G C +GQCVC + C Q C
Sbjct: 392 ECDD---------GFTGADCGELKC--PNGCSGHGRC--VNGQCVCDEGYTGEDCSQLRC 438
Query: 729 LDGFYRLQTNDVFGCTECDCDIG-GSIDNNCDKTTGQCHCHSRVEGRRC 776
+ + + V G +C C+ G D + CH H R C
Sbjct: 439 PNDCHS-RGRCVEG--KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMC 484
Score = 54.8 bits (126), Expect = 6e-06
Identities = 93/358 (25%), Positives = 126/358 (35%), Gaps = 66/358 (18%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQC---NGHSDQCDVNTGICLNCADN--TI 1789
C C ++G +C E G+ L G C+ QC +G + + +C D +
Sbjct: 174 CVCEPGWKGPNCSEPECPGNCHL-RGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCV 232
Query: 1790 GDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS--CNCQPGY 1847
C C GY D C CP+P C E+G+ + C C G+
Sbjct: 233 NGVC-ICFEGYAAD--------CSREICPVP---------CS-EEHGTCVDGLCVCHDGF 273
Query: 1848 GGARCE--YCAAGYY--GIPEDTDLHTGDYCKPCNCSGNINPQD---PGSCDSINGDCLK 1900
G C C Y G + + + +CS I P D G C ING C
Sbjct: 274 AGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCY- 330
Query: 1901 CVNNTAGAACN--LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
C G C C + + C+CDE G A D + C G
Sbjct: 331 CEEGFTGEDCGKPTCPHACHTQGRCEEG--QCVCDE-GFAGVDCSEKRCPADCHNRGRCV 387
Query: 1959 D-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
D RC D G C G + +C NGQC C +G TG+ C Q ++
Sbjct: 388 DGRCECDDGFTGADCGELKCPNGCSGHG-RCV--NGQCVCDEGYTGEDCSQLRCPNDCHS 444
Query: 2018 KDGC--DHCNCNTGYSVGFMCN--------------ATGQCECLPGVIGEKC-DR-CP 2057
+ C C C G+ G+ C+ G C C G GE C DR CP
Sbjct: 445 RGRCVEGKCVCEQGFK-GYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCP 501
Score = 54.0 bits (124), Expect = 1e-05
Identities = 98/378 (25%), Positives = 127/378 (33%), Gaps = 87/378 (23%)
Query: 1750 CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNT---IGDHCEFCMSGYHGD--A 1804
C+E H G CV C D C N +CLN N + + C C G+ G+ +
Sbjct: 255 CSEEHGTCVDGLCV-CHDGFAGDDC--NKPLCLNNCYNRGRCVENEC-VCDEGFTGEDCS 310
Query: 1805 TVGTPRDCL--------ICACPMPYPSNNFAL-----SCDLSENGSLISCNCQPGYGGAR 1851
+ P DC C C + + +C C C G+ G
Sbjct: 311 ELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVD 370
Query: 1852 C--EYCAAGYY-------GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCV 1902
C + C A + G E D TG C C + G C +NG C+ C
Sbjct: 371 CSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGH--GRC--VNGQCV-CD 425
Query: 1903 NNTAGAACN-LCAPGFYGDAIFSKNCTA--CICDE-FGMADCDSTT-------------G 1945
G C+ L P D C C+C++ F DC + G
Sbjct: 426 EGYTGEDCSQLRCPN---DCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNG 482
Query: 1946 TCVCRPGVIGEKC-DRCAPDHWGLNTGL----------GCTPCNCGIASESTQCDDD--- 1991
CVC G GE C DR P N GL G T +C S C
Sbjct: 483 MCVCDDGYTGEDCRDRQCPRDCS-NRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRC 541
Query: 1992 -NGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNTGY--------SVGFMCNATG 2040
NGQC C +G GK C +C + + C C+ G+ S CN G
Sbjct: 542 VNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLG 601
Query: 2041 QCE-----CLPGVIGEKC 2053
QC C G GE C
Sbjct: 602 QCVSGRCICNEGYSGEDC 619
Score = 50.0 bits (114), Expect = 2e-04
Identities = 69/275 (25%), Positives = 105/275 (38%), Gaps = 55/275 (20%)
Query: 1735 ECQCPRAYRGLSCEQ--C-AEGHYRLPSGFCVP--CQCNGHSDQCDVNTGICLN-CADN- 1787
+C C + G+ C + C A+ H R G CV C+C+ D C N C+ +
Sbjct: 359 QCVCDEGFAGVDCSEKRCPADCHNR---GRCVDGRCECDDGFTGADCGELKCPNGCSGHG 415
Query: 1788 -TIGDHCEFCMSGYHGD--ATVGTPRDCLI--------CACPMPYPSNNFA-LSC--DLS 1833
+ C C GY G+ + + P DC C C + + + +SC D
Sbjct: 416 RCVNGQC-VCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCH 474
Query: 1834 ENGSLIS--CNCQPGYGGARCE--YCA--AGYYGIPED-----TDLHTGDYCKPCNCSGN 1882
++G ++ C C GY G C C G+ D D TG C +C +
Sbjct: 475 QHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND 534
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACN--LCAPGFYGDA-------IFSKNCTACICD 1933
+ Q G C +NG C+ C G C C +G I + T C
Sbjct: 535 CHGQ--GRC--VNGQCV-CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 589
Query: 1934 EFGM-ADCDS----TTGTCVCRPGVIGEKCDRCAP 1963
+ +DC++ +G C+C G GE C +P
Sbjct: 590 QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSP 624
Score = 48.4 bits (110), Expect = 5e-04
Identities = 56/200 (28%), Positives = 77/200 (38%), Gaps = 31/200 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G T +C+ +CP + GR C G+ G+ +C CP+
Sbjct: 422 CVCD-EGYTGEDCSQL--RCPNDCHSRGRCVEGKCVCEQGFKGY-DCSDMSCPNDCHQHG 477
Query: 1397 ---NGMCICPKNVEGENC-DR-----CKPYTFNFDVQRGCDD----CNCNPLGVVGN-QL 1442
NGMC+C GE+C DR C D Q C+D +C L +
Sbjct: 478 RCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHG 537
Query: 1443 QCEADSGKCACRENVRGRVC--DHCVPGHYAFPDCY--QCTCNRHGTTYDVCDQNTAQCY 1498
Q +G+C C E G+ C C + C QC C+ T D C Q++
Sbjct: 538 QGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLD-CGQHSCPSD 596
Query: 1499 CKTNVRGQACD---TCKEEY 1515
C N GQ C E Y
Sbjct: 597 C--NNLGQCVSGRCICNEGY 614
Score = 41.1 bits (92), Expect = 0.073
Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 29/149 (19%)
Query: 1340 CLCDFMGSTELECNTFGGQCP--CKPN--VIGRTCSACRTGYYGFPNCRPCHCPSTAICD 1395
C+CD G T +C QCP C + C C G+ G P+C CP+
Sbjct: 484 CVCDD-GYTGEDCRD--RQCPRDCSNRGLCVDGQC-VCEDGFTG-PDCAELSCPNDCHGQ 538
Query: 1396 D---NGMCICPKNVEGENC--DRCKPYTFNFDVQRGCDD--CNCNP--LGVVGNQLQCEA 1446
NG C+C + G++C RC Q C D C C+ G+ Q C +
Sbjct: 539 GRCVNGQCVCHEGFMGKDCKEQRCPSDCHG---QGRCVDGQCICHEGFTGLDCGQHSCPS 595
Query: 1447 D--------SGKCACRENVRGRVCDHCVP 1467
D SG+C C E G C P
Sbjct: 596 DCNNLGQCVSGRCICNEGYSGEDCSEVSP 624
Score = 40.7 bits (91), Expect = 0.097
Identities = 50/198 (25%), Positives = 71/198 (35%), Gaps = 20/198 (10%)
Query: 1328 SITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPC 1386
S+ + +GA CL G L+ F C + N C C G+ G PNC
Sbjct: 135 SLREQCTAGAGCCLQPATG--RLDTRPF---CSGRGNFSTEGCGCVCEPGWKG-PNCSEP 188
Query: 1387 HCPSTAI----CDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQL 1442
CP C D G CIC GE+C + + + Q C + C + G
Sbjct: 189 ECPGNCHLRGRCID-GQCICDDGFTGEDCSQL-ACPSDCNDQGKCVNGVC--ICFEGYAA 244
Query: 1443 QCEADSGKCACRENVRGRVCDHCV-PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKT 1501
C + C E V CV +A DC + C + C +N +C C
Sbjct: 245 DCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVEN--ECVCDE 302
Query: 1502 NVRGQACD--TCKEEYFN 1517
G+ C C + F+
Sbjct: 303 GFTGEDCSELICPNDCFD 320
Score = 40.3 bits (90), Expect = 0.13
Identities = 59/236 (25%), Positives = 84/236 (35%), Gaps = 35/236 (14%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD 607
C TG T G+ N T G C C PG+ K P+C C + + C D
Sbjct: 147 CLQPATGRLDTRPFCSGRGNFSTE--GCGC-VCEPGW-KGPNCSEPECPGNCHLRGRCID 202
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV 667
G C C F G C Q C + GV F G + + E+C
Sbjct: 203 -GQCICDDGFTGEDCS----QLACPSDCNDQGKCVNGVCICFEGYAADCSREICPVPCSE 257
Query: 668 QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ 727
+ C D + ++ F + CN L L C + G+CV E +C
Sbjct: 258 EHGTCVDGLCVC-----HDGFAGDDCNKPLC-----LNNCYNR-GRCV------ENEC-V 299
Query: 728 CLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPIRAH 783
C +GF +++ +C D G I+ G C+C G C +P H
Sbjct: 300 CDEGFTGEDCSELICPNDC-FDRGRCIN-------GTCYCEEGFTGEDCGKPTCPH 347
Score = 37.9 bits (84), Expect = 0.68
Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDD-----NGMCICPKNVEGENCDR-CKPYTFNFDVQRG 1426
C G+ G +C CP+ C D NG C C + GE+C + P+ + Q
Sbjct: 300 CDEGFTG-EDCSELICPND--CFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH--TQGR 354
Query: 1427 CDD--CNCNP--LGVVGNQLQCEAD--------SGKCACRENVRGRVCDH--CVPGHYAF 1472
C++ C C+ GV ++ +C AD G+C C + G C C G
Sbjct: 355 CEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGH 414
Query: 1473 PDCY--QCTCNRHGTTYDVCDQ 1492
C QC C+ G T + C Q
Sbjct: 415 GRCVNGQCVCD-EGYTGEDCSQ 435
Score = 37.5 bits (83), Expect = 0.90
Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 18/177 (10%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA---CRTGYYGFPNCRPCHCPSTAICDD 1396
C+CD G ++C+ +CP + GR C G+ G +C CP+
Sbjct: 360 CVCD-EGFAGVDCSE--KRCPADCHNRGRCVDGRCECDDGFTG-ADCGELKCPNGCSGHG 415
Query: 1397 ---NGMCICPKNVEGENCDRCK-PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
NG C+C + GE+C + + P + + C C G G C S
Sbjct: 416 RCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQ-GFKG--YDCSDMSCPND 472
Query: 1453 CRENVRGRVCDHCV-PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C ++ R V CV Y DC C R + +C QC C+ G C
Sbjct: 473 CHQHGR-CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD--GQCVCEDGFTGPDC 526
>AB011536-1|BAA32464.1| 1364|Homo sapiens MEGF2 protein.
Length = 1364
Score = 91.1 bits (216), Expect = 7e-17
Identities = 58/166 (34%), Positives = 76/166 (45%), Gaps = 28/166 (16%)
Query: 427 CKYNYAGKSCEICEDGYYSPECKNC----ECNTVGSVSYVCDKLTG-DCTCKSKYSGRTC 481
C+ + SC C+ GYY P C + C GS ++ G C C Y G C
Sbjct: 8 CRDLWQTFSCT-CQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHC 66
Query: 482 N-----QCQAGYYNYPTCKPCNCDT-SGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
QC G++ PTC PCNCD G +P+ C+ +GQC CK PR
Sbjct: 67 EHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPN-CNKTNGQCHCKEFHYRPR--------- 116
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCSA-DGKCNCLTNFGGAQCDQC 580
G + C+PC+C P GSTS SC+ G+C C G QC+ C
Sbjct: 117 ----GSD-SCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 157
Score = 72.1 bits (169), Expect = 3e-11
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 33/175 (18%)
Query: 327 NCQHNTEGINCNKCRPTYYRPYGKRWDELDVC--QPCQCDPHFSTGNCEEESGR-----C 379
+C+ + +C C+P YY P +D C PCQ + G+C G C
Sbjct: 7 DCRDLWQTFSCT-CQPGYYGP-----GCVDACLLNPCQ-----NQGSCRHLPGAPHGYTC 55
Query: 380 ECRPEFQPPDCS-----SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCK-YNYAG 433
+C + C C G++ P C PC C+++ +C T+G C CK ++Y
Sbjct: 56 DCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRP 115
Query: 434 KSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGY 488
+ S C C+C VGS S C +G C C+ GR CN C + +
Sbjct: 116 RG---------SDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 161
Score = 70.1 bits (164), Expect = 1e-10
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 30/179 (16%)
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTG-----TCVCRPGVIGEKCD-----RCA 1962
C PG+YG C C G C G TC C G G C+ +C
Sbjct: 19 CQPGYYGPGCVDA-CLLNPCQNQG--SCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCP 75
Query: 1963 PDHWGLNTGLGCTPCNCGIASE-STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
WG T C PCNC + C+ NGQC C K+ G D C
Sbjct: 76 RGWWGSPT---CGPCNCDVHKGFDPNCNKTNGQCHC------KEFHYRPRG-----SDSC 121
Query: 2022 DHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKCDRCPERWVLIPQEGC-LECDSCTDAL 2078
C+C S C +GQC C PG +G +C+ C + + GC + D+C +L
Sbjct: 122 LPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCRVLYDACPKSL 180
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/168 (30%), Positives = 69/168 (41%), Gaps = 26/168 (15%)
Query: 380 ECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGE-HCTPTDGL-----CPCKYNYAG 433
+CR +Q C+ C GY+ P C C LN + + C G C C Y G
Sbjct: 7 DCRDLWQTFSCT-CQPGYYG-PGCVDA-CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFG 63
Query: 434 KSCEI-----CEDGYY-SPECKNCECNTVGSVSYVCDKLTGDCTCKS-KYSGRTCNQCQA 486
CE C G++ SP C C C+ C+K G C CK Y R +
Sbjct: 64 HHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSD---- 119
Query: 487 GYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGY 534
+C PC+C G+ C SGQC C+ G G +C+ C S +
Sbjct: 120 ------SCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 161
Score = 64.5 bits (150), Expect = 7e-09
Identities = 50/168 (29%), Positives = 67/168 (39%), Gaps = 35/168 (20%)
Query: 516 CICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGG 574
C C+ G+ GP C D CL + + C P G T C+C+ + G
Sbjct: 17 CTCQPGYYGPGCVDACL----LNPCQNQGSCRHLPGAPHGYT---------CDCVGGYFG 63
Query: 575 AQCD-----QCSPGYYKYPDCLSCNCDVSGSIGSTCD-DNGLCHCKS-NFDGAKCDTCRE 627
C+ QC G++ P C CNCDV C+ NG CHCK ++ D+C
Sbjct: 64 HHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCL- 122
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDC 675
C+C P G T+ C P C C+ GR CN C
Sbjct: 123 ---------PCDCYPVGSTS--RSC--APHSGQCPCRPGALGRQCNSC 157
Score = 62.1 bits (144), Expect = 4e-08
Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 29/164 (17%)
Query: 1871 GDYCKPCNCSGNINP-QDPGSCDSI----NGDCLKCVNNTAGAACN-----LCAPGFYGD 1920
G Y C + +NP Q+ GSC + +G CV G C C G++G
Sbjct: 22 GYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWG- 80
Query: 1921 AIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCN 1978
S C C CD D C+ T G C C+ H+ C PC+
Sbjct: 81 ---SPTCGPCNCDVHKGFDPNCNKTNGQCHCKEF------------HYRPRGSDSCLPCD 125
Query: 1979 C-GIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGC 2021
C + S S C +GQC C G G+QC+ C + F T GC
Sbjct: 126 CYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGC 169
Score = 61.3 bits (142), Expect = 6e-08
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 352 WDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNL 410
W C PC CD H NC + +G+C C+ P S +C PC C
Sbjct: 78 WWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSD---------SCLPCDCYP 128
Query: 411 NGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
G+ C P G CPC+ G+ C C+ + C
Sbjct: 129 VGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGC 169
Score = 57.2 bits (132), Expect = 1e-06
Identities = 52/167 (31%), Positives = 61/167 (36%), Gaps = 24/167 (14%)
Query: 240 CEP-ADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTT 298
C P AD C CQ GP C C QN P H +T
Sbjct: 2 CPPHADCRDLWQTFSCTCQPGYYGPGCVDAC------LLNPCQNQGSCRHLPGAPHGYTC 55
Query: 299 ECT--YDPEIDEKRLSLDINGRYEGGGKC--LNCQ-HNTEGINCNK------CRPTYYRP 347
+C Y E R+ + G C NC H NCNK C+ +YRP
Sbjct: 56 DCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRP 115
Query: 348 YGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSC 393
G D C PC C P ST +C SG+C CRP C+SC
Sbjct: 116 RGS-----DSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 157
Score = 56.0 bits (129), Expect = 2e-06
Identities = 42/165 (25%), Positives = 60/165 (36%), Gaps = 17/165 (10%)
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C+ + C TC+ +Y + C +P S P G C C G C
Sbjct: 8 CRDLWQTFSC-TCQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHC 66
Query: 673 NDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGF 732
+ C CNC++ + CN +GQC CK+
Sbjct: 67 EHRMDQQCPRGWWGSPTCGPCNCDVHKGFDP--NCNKTNGQCHCKEF------------H 112
Query: 733 YRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
YR + +D C CDC GS +C +GQC C GR+C+
Sbjct: 113 YRPRGSD--SCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCN 155
Score = 55.6 bits (128), Expect = 3e-06
Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 18/165 (10%)
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPC---NCDTSGTEPSICDDVSGQ-CICKAGFGGPRC 527
C+ + +C CQ GYY C C G+ + G C C G+ G C
Sbjct: 8 CRDLWQTFSCT-CQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHC 66
Query: 528 DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLT-NFGGAQCDQCSPGYY 585
+ + + C PCNCD +C+ +G+C+C ++ D C P
Sbjct: 67 EHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLP--- 123
Query: 586 KYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCDTCREQF 629
C+C GS +C +G C C+ G +C++C F
Sbjct: 124 -------CDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 161
Score = 52.8 bits (121), Expect = 2e-05
Identities = 49/173 (28%), Positives = 65/173 (37%), Gaps = 41/173 (23%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY+G V CL+ C N L +C+C GY G CE+
Sbjct: 19 CQPGYYGPGCVDA---CLLNPC------QNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHR 69
Query: 1855 ----CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C G++G P C PCNC + DP +C+ NG C C
Sbjct: 70 MDQQCPRGWWGSPT---------CGPCNCDVH-KGFDP-NCNKTNGQC-HCKE------- 110
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRC 1961
F+ S +C C C G C +G C CRPG +G +C+ C
Sbjct: 111 ------FHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 157
Score = 52.0 bits (119), Expect = 4e-05
Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 35/176 (19%)
Query: 1360 PCKPNV----IGRTCSA-CRTGYYGFPNCRPCHCPSTAICDDNGMCI-CPKNVEGENCDR 1413
PC P+ + +T S C+ GYYG P C C C + G C P G CD
Sbjct: 1 PCPPHADCRDLWQTFSCTCQPGYYG-PGCVDA-CLLNP-CQNQGSCRHLPGAPHGYTCDC 57
Query: 1414 CKPY-----TFNFDVQ--RG------CDDCNCNPLGVVGNQLQCEADSGKCACRE-NVRG 1459
Y D Q RG C CNC+ G C +G+C C+E + R
Sbjct: 58 VGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHK--GFDPNCNKTNGQCHCKEFHYRP 115
Query: 1460 RVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
R D C+P C C G+T C ++ QC C+ G+ C++C +
Sbjct: 116 RGSDSCLP----------CDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPF 161
Score = 50.4 bits (115), Expect = 1e-04
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1317 NET-GLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
N+T G C F + PC C +GST C GQCPC+P +GR C++C
Sbjct: 100 NKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSC 157
Score = 49.2 bits (112), Expect = 3e-04
Identities = 38/119 (31%), Positives = 49/119 (41%), Gaps = 18/119 (15%)
Query: 656 PAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC---NCNLAGTLNSL-GACNTKS 711
P C+D Q C C+P Y Y P + C C G+ L GA + +
Sbjct: 1 PCPPHADCRDLWQTFSCT-CQPGY-----YGPGCVDACLLNPCQNQGSCRHLPGAPHGYT 54
Query: 712 GQCV---CKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
CV H R QC G++ T C C+CD+ D NC+KT GQCHC
Sbjct: 55 CDCVGGYFGHHCEHRMDQQCPRGWWGSPT-----CGPCNCDVHKGFDPNCNKTNGQCHC 108
Score = 44.4 bits (100), Expect = 0.008
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 32/160 (20%)
Query: 580 CSPGYYKYPDCL-SCNCDVSGSIGSTCDDNGL-----CHCKSNFDGAKCD-----TCREQ 628
C PGYY P C+ +C + + GS G C C + G C+ C
Sbjct: 19 CQPGYYG-PGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRG 77
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPF 688
++ P C CNCD V F + G+ C CK+ ++ +
Sbjct: 78 WWGSPTCGPCNCD---VHKGFDPNCNKTNGQ-CHCKE--------------FHYRPRGSD 119
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQC 728
C C+C G+ + +C SGQC C+ RQC+ C
Sbjct: 120 SCLPCDCYPVGSTSR--SCAPHSGQCPCRPGALGRQCNSC 157
Score = 44.4 bits (100), Expect = 0.008
Identities = 59/203 (29%), Positives = 76/203 (37%), Gaps = 34/203 (16%)
Query: 1736 CQCPRAYRGLSCE-----QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
C C Y G CE QC G + P+ C PC C DV+ G NC
Sbjct: 55 CDCVGGYFGHHCEHRMDQQCPRGWWGSPT--CGPCNC-------DVHKGFDPNCNKTNGQ 105
Query: 1791 DHC-EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
HC EF D+ CL C C YP + + SC +G C C+PG G
Sbjct: 106 CHCKEFHYRPRGSDS-------CLPCDC---YPVGSTSRSC-APHSGQ---CPCRPGALG 151
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDP-GSCDSINGDCLKCVNNTAGA 1908
+C C + + + D C SG PQ G ++ AGA
Sbjct: 152 RQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALGLRGAGA 211
Query: 1909 ACNLC--APGFYGDAIFSKNCTA 1929
A LC A G+ +F NCT+
Sbjct: 212 AVRLCDEAQGWLEPDLF--NCTS 232
Score = 38.3 bits (85), Expect = 0.52
Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 6/77 (7%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKP-NVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
PC CD + CN GQC CK + R +C +C P S + +
Sbjct: 86 PCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLP-----CDCYPVGSTSRSCAPHS 140
Query: 1398 GMCICPKNVEGENCDRC 1414
G C C G C+ C
Sbjct: 141 GQCPCRPGALGRQCNSC 157
>BC067813-1|AAH67813.1| 248|Homo sapiens LAMC1 protein protein.
Length = 248
Score = 90.6 bits (215), Expect = 9e-17
Identities = 51/157 (32%), Positives = 80/157 (50%), Gaps = 6/157 (3%)
Query: 31 TSVCDICDANNEAKKHPPEYAVDDRR----TWWQSPPLSRGMKY-NEVNLTIDLGQEFHV 85
T C +CDA +H + D TWWQS + G++Y + +NLT+ LG+ F +
Sbjct: 86 TKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDI 145
Query: 86 AYVFVKMGNSPRPELWVLEKSTDYGKTFKPWQYFSDSPQDCERYFGKESLQPITKDDSVI 145
YV +K S RPE + + K T + P+QY+S S ++ + ++ + +
Sbjct: 146 TYVRLKFHTS-RPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQAL 204
Query: 146 CSTEYSKIVPLEDGEIPISLLNDRPSSNMYFNSSVLQ 182
C+ E+S I PL G + S L RPS+ + NS VLQ
Sbjct: 205 CTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQ 241
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 90.2 bits (214), Expect = 1e-16
Identities = 157/639 (24%), Positives = 222/639 (34%), Gaps = 108/639 (16%)
Query: 211 DPTVTRRYFYSIKDISIGGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCN 266
DPT + + G C NG+ C+P N +I C+ N C G C
Sbjct: 710 DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCK 769
Query: 267 KCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCL 326
SG + + FS NC + EC +P +++ D+ G KC
Sbjct: 770 DMTSGI------VCTCREGFSGP--NCQTNINECASNPCLNKGTCIDDV-----AGYKC- 815
Query: 327 NCQHNTEGINCN----KCRPTYYRPYGK-RWDELDVCQPCQCDPHFSTGN-CEEESGRCE 380
NC G C C P+ R G+ R E C C + G CE + C
Sbjct: 816 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECV 875
Query: 381 CRPEFQPPDCSS--------CAYGYF------DYPNCKPCTCNLNGTEGEHCTP--TDGL 424
P C + C GY D +C+P C+ G+ CT
Sbjct: 876 LSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS----CTDGINTAF 931
Query: 425 CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
C C + G CE ED EC + C + + D T CTC + +SG C
Sbjct: 932 CDCLPGFRGTFCE--ED---INECASDPCRNGANCTDCVDSYT--CTCPAGFSGIHCEN- 983
Query: 485 QAGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQ--VLGR 541
N P C +C GT D ++ C+C GF G C ++ + +LG
Sbjct: 984 -----NTPDCTESSCFNGGT---CVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGG 1035
Query: 542 E----RQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQ--------CSPGYYK-Y 587
R C C P G T +C + C+ G +C Q C G+ Y
Sbjct: 1036 TCQDGRGLHRCTC-PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLY 1094
Query: 588 PDCLSCNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
D S +C+V+ + C GLC N +C Y +EC+ P
Sbjct: 1095 CDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP 1154
Query: 643 --RGVTAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
G T + + G C V C + + + + C+ L N + C C
Sbjct: 1155 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS-CPRG 1213
Query: 697 LAGTLNSLGA--CN------TKSGQC----VCKQHVGERQCDQCLDGFYRLQTN-DVFGC 743
G + CN ++S +C C VG C C GF + DV C
Sbjct: 1214 TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT-CPPGFVGERCEGDVNEC 1272
Query: 744 TECDCDIGGSIDNNCDKTTGQCHCHSRV--EGRRCDQPI 780
CD G+ NC + HC R GRRC+ I
Sbjct: 1273 LSNPCDARGT--QNCVQRVNDFHCECRAGHTGRRCESVI 1309
Score = 87.8 bits (208), Expect = 6e-16
Identities = 142/591 (24%), Positives = 190/591 (32%), Gaps = 99/591 (16%)
Query: 239 TCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWDRF--SCEP--- 290
TC+ D N +C C T GP C C+ D + +CEP
Sbjct: 617 TCQDPD-----NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYT 671
Query: 291 -CNCHNHTTECTYDPEIDEKRLSLDING---RYEGGGKCLNCQHNTEGINCNKCRPTYYR 346
C+++ EC +P + ING R G C N N C
Sbjct: 672 GSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC------ 725
Query: 347 PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGY-------FD 399
+G D L+ + C CDP +S NC+ + CE P C G F
Sbjct: 726 VHGACRDSLNGYK-CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFS 784
Query: 400 YPNCK----PCTCNLNGTEGEHCTPTDGL-CPCKYNYAGKSCEI---------CEDG--- 442
PNC+ C N +G G C C Y G +CE+ C +G
Sbjct: 785 GPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC 844
Query: 443 --YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN--------QCQAGYYNYP 492
E +C C T G+ C+ +C G +C CQAGY
Sbjct: 845 RQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY---- 900
Query: 493 TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDP 552
+ + C D P+ C + C G CD CL G+ E C DP
Sbjct: 901 SGRNCETDIDDCRPNPCHNGGS---CTDGINTAFCD-CLPGFRGTFC--EEDINECASDP 954
Query: 553 --TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--- 607
G+ T C C C F G C+ PDC +C G TC D
Sbjct: 955 CRNGANCTDCVDSYTCTCPAGFSGIHCEN------NTPDCTESSC----FNGGTCVDGIN 1004
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNC-DPRGVTASFAGCGSVPAGELCQCKDR 666
+ C C F G+ C + + P C D RG+ C G CQ +
Sbjct: 1005 SFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHR--CTCPQGYTGPNCQ--NL 1060
Query: 667 VQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC-VCKQHVGERQC 725
V + CK Q + + CE C G C+ S C V Q G
Sbjct: 1061 VHWCDSSPCKNGGKCWQTHTQYRCE-CPSGWTGLY-----CDVPSVSCEVAAQRQGVDVA 1114
Query: 726 DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C G + + C C GS C+ +C G C
Sbjct: 1115 RLCQHGGLCVDAGNTHHC-RCQAGYTGSY---CEDLVDECSPSPCQNGATC 1161
Score = 83.8 bits (198), Expect = 1e-14
Identities = 142/576 (24%), Positives = 205/576 (35%), Gaps = 111/576 (19%)
Query: 253 VCRCQHNTCGPQCNK----CCSGFE--QKKWRISQNWDRFSCEPCN------CHNHTTEC 300
+C C GP C++ C G + + F C+ C EC
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC 456
Query: 301 TYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINC----NKCRPTYYRPYGKRWDELD 356
+P LD G ++ C+ C EG++C ++C + G+ D+++
Sbjct: 457 VSNP-CQNDATCLDQIGEFQ----CM-CMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
Query: 357 VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGE 416
Q C+C F+ C+ + C P C D PN C C G G
Sbjct: 511 EFQ-CECPTGFTGHLCQYDVDECASTPCKNGAKC-------LDGPNTYTCVCT-EGYTGT 561
Query: 417 HCTPTDGLC---PCKYN-----YAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG 468
HC C PC Y A +C +C GY +CE N S C +L G
Sbjct: 562 HCEVDIDECDPDPCHYGSCKDGVATFTC-LCRPGYTG---HHCETNINECSSQPC-RLRG 616
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPTCKPC--NCDTSGTEPSIC-DDVSG-QCICKAGFGG 524
TC+ + C C G P C+ +C +S + C D + G +C C+ G+ G
Sbjct: 617 --TCQDPDNAYLCF-CLKGTTG-PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTG 672
Query: 525 PRC----DQCLSGYYMQVLGRERQCV---PCNCDPTGSTSTSCSAD-GKCN--------C 568
C D+C +G G + C C P G +C ++ +CN C
Sbjct: 673 SMCNSNIDEC-AGNPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECNSNPCVHGAC 730
Query: 569 LTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI--GSTCDDNGLCHCKSNFDGAKCDTCR 626
+ G +CD C PG+ NCD++ + + C + G C K G C TCR
Sbjct: 731 RDSLNGYKCD-CDPGWS------GTNCDINNNECESNPCVNGGTC--KDMTSGIVC-TCR 780
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
E F P C+ + C S P C D V G CN P E
Sbjct: 781 EGFSG-PNCQ----------TNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVV 829
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
C C G + + +S CVC + Q + D+ C
Sbjct: 830 LAPCAPSPCRNGGECRQ--SEDYESFSCVCPTAGAKGQTCEV----------DINECVLS 877
Query: 747 DCDIGGSIDNNCDKTTG--QCHCHSRVEGRRCDQPI 780
C G S C T G +CHC + GR C+ I
Sbjct: 878 PCRHGAS----CQNTHGXYRCHCQAGYSGRNCETDI 909
Score = 81.4 bits (192), Expect = 6e-14
Identities = 122/483 (25%), Positives = 168/483 (34%), Gaps = 75/483 (15%)
Query: 321 GGGKCLNCQHNTEGINCNK----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES 376
G +C+ C+ G NC + C P+ + G DV C C P F+ NCEE
Sbjct: 200 GSYRCV-CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA--GK 434
C P + +C G Y NC PC G++CT C N G
Sbjct: 259 DDC---PGNNCKNGGACVDGVNTY-NC-PCPPEWT---GQYCTEDVDECQLMPNACQNGG 310
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY----N 490
+C GY NC C G C + DC + + G TC+ A +Y +
Sbjct: 311 TCHNTHGGY------NCVC-VNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 491 YPTCKPCNCDTS-----GTEPSICD--DVSGQ--CICKAGFGGPRC----DQCL------ 531
T C+ + + E S CD V+G+ C C +G+ GP C D+C
Sbjct: 364 GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPC 423
Query: 532 --SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSP 582
+G + LG E QC+ C D S C D CL G QC C P
Sbjct: 424 EHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND--ATCLDQIGEFQC-MCMP 480
Query: 583 GYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
GY + + C + S C NG C K N +C T +EC P
Sbjct: 481 GY----EGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTP 536
Query: 643 RGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
+ A C P C C + G C ++ E +P C +C G
Sbjct: 537 ---CKNGAKCLDGPNTYTCVCTEGYTGTHCE------VDIDECDPDPCHYGSCK-DGVAT 586
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT 762
C C+ ++ E C R D C C + G+ NC+
Sbjct: 587 FTCLCRPGYTGHHCETNINECSSQPCR---LRGTCQDPDNAYLCFC-LKGTTGPNCEINL 642
Query: 763 GQC 765
C
Sbjct: 643 DDC 645
Score = 77.4 bits (182), Expect = 9e-13
Identities = 137/563 (24%), Positives = 191/563 (33%), Gaps = 109/563 (19%)
Query: 227 IGGRCMCNG--HADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
+GG C H TC N LV C + C KC Q + W
Sbjct: 1033 LGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPC-KNGGKCWQTHTQYRCECPSGWT 1091
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C+ + C E+ +R +D+ + GG C++ NT +C +C+ Y
Sbjct: 1092 GLYCDV-----PSVSC----EVAAQRQGVDVARLCQHGGLCVDAG-NTH--HC-RCQAGY 1138
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSS---------C 393
Y + D +D C P C + C + G C+C + +CS C
Sbjct: 1139 TGSYCE--DLVDECSPSPCQ---NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPC 1193
Query: 394 AYG--YFDYPNCKPCTCNLNGTEGEHCT--------PTDGL-----C----PCKYNYAGK 434
G D PN C+C GT+G HC P D + C C G
Sbjct: 1194 QNGGTCLDLPNTYKCSCP-RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGY 1252
Query: 435 SCEICEDGYYSPECKN----C---ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
SC C G+ C+ C C+ G+ + V C C++ ++GR C G
Sbjct: 1253 SCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVING 1311
Query: 488 YYNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLSGYYMQVLGRERQCV 546
CK C GT + G C C AGF G C+ R C
Sbjct: 1312 ------CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN-----------DARTCG 1354
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN-CDVSGSIGSTC 605
C G T S C CL F G +C + CL N C G+ T
Sbjct: 1355 SLRC-LNGGTCISGPRSPTCLCLGPFTGPECQ-----FPASSPCLGGNPCYNQGTCEPTS 1408
Query: 606 DDNGL-CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV--TASFAGCGSVPAGELC- 661
+ C C + F+G C Y++ + P + C ++C
Sbjct: 1409 ESPFYRCLCPAKFNGLLCHILD---YSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCS 1465
Query: 662 -QCKDRVQGRICNDCKPLY---W-----NLQEYNPFGCEQCN--CNLAGTLNSLGACNTK 710
QC + G DC + W +LQ + F C+ CN AG L C
Sbjct: 1466 LQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA 1525
Query: 711 SGQC------VCKQHVGERQCDQ 727
GQC CK H + CDQ
Sbjct: 1526 EGQCNPLYDQYCKDHFSDGHCDQ 1548
Score = 70.5 bits (165), Expect = 1e-10
Identities = 94/360 (26%), Positives = 130/360 (36%), Gaps = 58/360 (16%)
Query: 1735 ECQCPRAYRGLSCE----QCAEGHYRLPSGFCVP------CQC----NGHSDQCDVN--- 1777
+C C Y G+ CE +CA L +G C+ C+C GH Q DV+
Sbjct: 475 QCMCMPGYEGVHCEVNTDECASSPC-LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA 533
Query: 1778 TGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ C N C D C C GY GT + I C P P + SC +
Sbjct: 534 STPCKNGAKCLDGPNTYTC-VCTEGY-----TGTHCEVDIDECD-PDPCHYG--SC--KD 582
Query: 1835 NGSLISCNCQPGYGGARCEY----CAAG---YYGIPEDTDLHTGDYCKPC----NCSGNI 1883
+ +C C+PGY G CE C++ G +D D +C NC N+
Sbjct: 583 GVATFTCLCRPGYTGHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINL 642
Query: 1884 NPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCD 1941
+ CDS G CL ++ G C C PG+ G S C C G +
Sbjct: 643 DDCASSPCDS--GTCLDKID---GYEC-ACEPGYTGSMCNSNIDECAGNPCHNGGTCEDG 696
Query: 1942 STTGTCVCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQ 1994
TC C G C + C + H L C+C T CD +N +
Sbjct: 697 INGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNE 756
Query: 1995 CRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C V G C +G ++G NC T + + C+ V G KC+
Sbjct: 757 CESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYKCN 816
Score = 68.9 bits (161), Expect = 3e-10
Identities = 117/475 (24%), Positives = 167/475 (35%), Gaps = 83/475 (17%)
Query: 254 CRCQHNTCGPQC----NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
CRCQ G C ++C Q + +SC+ C H C+ EIDE
Sbjct: 1132 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCK-CVAGYHGVNCS--EEIDEC 1188
Query: 310 RLSLDINGRYEGGGKCLN--------CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
++ + GG CL+ C T+G++C P D + C
Sbjct: 1189 -----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV----DPVSRSPKC 1239
Query: 362 QCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
F+ G C ++ G C C P F C D C C+ GT+
Sbjct: 1240 -----FNNGTCVDQVGGYSCTCPPGFVGERCEG------DVNECLSNPCDARGTQNCVQR 1288
Query: 420 PTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG-DCTCKSKYSG 478
D C C+ + G+ CE +G CK C G+ + + G C C + + G
Sbjct: 1289 VNDFHCECRAGHTGRRCESVING-----CKGKPCKNGGTCAVASNTARGFICKCPAGFEG 1343
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQV 538
TC + TC C GT I S C+C F GP C S
Sbjct: 1344 ATCEN------DARTCGSLRCLNGGT--CISGPRSPTCLCLGPFTGPECQFPASS---PC 1392
Query: 539 LGRERQCVPCNCDPTG-STSTSCSADGKCNCLT------NF-GGAQCDQCSPGYYKYPDC 590
LG C+PT S C K N L +F GGA D P + +
Sbjct: 1393 LGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACEL 1452
Query: 591 LSCNCDVSGSIGSTCDDNGLC-----HCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV 645
C D + S +N C C NF+ C + + + +CD +
Sbjct: 1453 PECQEDAGNKVCSLQCNNHACGWDGGDCSLNFND-PWKNCTQSLQCWKYFSDGHCDSQ-- 1509
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY--WNLQEYNPFGCEQCNCNLA 698
+ AGC + G CQ R +G+ C PLY + ++ C+Q CN A
Sbjct: 1510 -CNSAGC--LFDGFDCQ---RAEGQ----CNPLYDQYCKDHFSDGHCDQ-GCNSA 1553
Score = 64.9 bits (151), Expect = 5e-09
Identities = 85/330 (25%), Positives = 118/330 (35%), Gaps = 56/330 (16%)
Query: 1767 CNGHSDQCDVNTGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CN + D+C N C N C D G C C GYH + +C C
Sbjct: 675 CNSNIDECAGNP--CHNGGTCEDGINGFTCR-CPEGYHDPTCLSEVNECNSNPCVHG--- 728
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-----EDTDLHTGDYCKPC- 1877
+C S NG C+C PG+ G C+ P D+ +G C C
Sbjct: 729 -----ACRDSLNG--YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCT-CR 780
Query: 1878 ------NCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAP--GFYGDAIFSKNCTA 1929
NC NIN C +N C+++ AG CN P G + + + C
Sbjct: 781 EGFSGPNCQTNINECASNPC--LNKGT--CIDDVAGYKCNCLLPYTGATCEVVLAP-CAP 835
Query: 1930 CICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ 1987
C G D + +CVC G K C D +N + +PC G + ++T
Sbjct: 836 SPCRNGGECRQSEDYESFSCVCPTA--GAKGQTCEVD---INECV-LSPCRHGASCQNTH 889
Query: 1988 CDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPG 2047
+C C G +G+ C+ D C C+ G S N T C+CLPG
Sbjct: 890 ---GXYRCHCQAGYSGRNCETDI--------DDCRPNPCHNGGSCTDGIN-TAFCDCLPG 937
Query: 2048 VIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
G C+ P C C D+
Sbjct: 938 FRGTFCEEDINECASDPCRNGANCTDCVDS 967
Score = 64.5 bits (150), Expect = 7e-09
Identities = 100/375 (26%), Positives = 127/375 (33%), Gaps = 44/375 (11%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC+ G +C+ G GF P C + ++C N CLN C D+ G
Sbjct: 756 ECESNPCVNGGTCKDMTSGIVCTCREGFSGP-NCQTNINECASNP--CLNKGTCIDDVAG 812
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP-GYGG 1849
C C+ Y G AT + ++ C P P N C SE+ SC C G G
Sbjct: 813 YKCN-CLLPYTG-ATC----EVVLAPCA-PSPCRNGG-ECRQSEDYESFSCVCPTAGAKG 864
Query: 1850 ARCEY----CAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDC 1898
CE C G Y C NC +I+ P C + G C
Sbjct: 865 QTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHN-GGSC 923
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF-GMADCDSTTG--TCVCRPGVIG 1955
+N A C+ C PGF G ++ C D A+C TC C G G
Sbjct: 924 TDGINT---AFCD-CLPGFRG-TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSG 978
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN 2015
C+ PD + G T C GI S + C C V C G
Sbjct: 979 IHCENNTPDCTESSCFNGGT-CVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTC 1037
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
G C C GY+ N C+ P G KC W Q C EC S
Sbjct: 1038 QDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC------WQTHTQYRC-ECPSGW 1090
Query: 2076 DALIFSVEDLSALLA 2090
L V +S +A
Sbjct: 1091 TGLYCDVPSVSCEVA 1105
Score = 63.7 bits (148), Expect = 1e-08
Identities = 114/460 (24%), Positives = 155/460 (33%), Gaps = 75/460 (16%)
Query: 360 PCQCDPHFSTGNCEEESGR------CECRPEFQPPDCSSCAYGYFDYPNCKPCTCN--LN 411
PC P + G C R C C F P C + P C N N
Sbjct: 62 PCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT--------PLDNACLTNPCRN 113
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + T T+ C C ++GKSC+ + +P +C SY+C
Sbjct: 114 GGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPF-EASYICH------- 165
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQ 529
C + G TC Q N KP C GT C + G +C+C+A GP C++
Sbjct: 166 CPPSFHGPTCRQ----DVNECGQKPRLCRHGGT----CHNEVGSYRCVCRATHTGPNCER 217
Query: 530 ---------CLSGYYMQVLG---RERQCVP----CNCDPT--GSTSTSCSADGKCNCLTN 571
C +G + G E C+P NC+ +C G C N
Sbjct: 218 PYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN 277
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCDD--NGL-CHCKSNFDGAKCDTCRE 627
C G Y D C + G TC + G C C + + G C +
Sbjct: 278 TYNCPCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENID 337
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN-----DCKPLYWNL 682
+ C R V + + C G LC D CN D P+
Sbjct: 338 DCASAACFHGATCHDR-VASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGA--CNTKSGQCVCKQHVGERQCDQCLDGFYRLQTN-D 739
P G C+ SLGA C +G+C+ +G +C QCL G+ + D
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCE-HAGKCI--NTLGSFEC-QCLQGYTGPRCEID 452
Query: 740 VFGCTECDCDIGGSIDNNCDKTTG--QCHCHSRVEGRRCD 777
V C C D C G QC C EG C+
Sbjct: 453 VNECVSNPC----QNDATCLDQIGEFQCMCMPGYEGVHCE 488
Score = 62.1 bits (144), Expect = 4e-08
Identities = 92/376 (24%), Positives = 132/376 (35%), Gaps = 57/376 (15%)
Query: 1731 TSVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTI 1789
++++EC + G +CE G R P G+ P C ++C+ N + C D+
Sbjct: 677 SNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPT-CLSEVNECNSNPCVHGACRDSLN 735
Query: 1790 GDHCEFCMSGYHGD--------------ATVGTPRDC---LICACPMPYPSNNFALSC-D 1831
G C+ C G+ G GT +D ++C C + N + +
Sbjct: 736 GYKCD-CDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINE 794
Query: 1832 LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC 1891
+ N L C G +C C Y G + L C P C ++ G C
Sbjct: 795 CASNPCLNKGTCIDDVAGYKCN-CLLPYTGATCEVVLAP---CAPSPC------RNGGEC 844
Query: 1892 -DSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGT--CV 1948
S + + CV TAGA C + C C G A C +T G C
Sbjct: 845 RQSEDYESFSCVCPTAGAKGQTCE-------VDINECVLSPC-RHG-ASCQNTHGXYRCH 895
Query: 1949 CRPGVIGEKC----DRCAPD--HWG--LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C+ G G C D C P+ H G G+ C+C T C++D +C
Sbjct: 896 CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPC 955
Query: 2001 VTGKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
G C C + G HC NT C G C+ G+ C CP
Sbjct: 956 RNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG--TCVDGINSFTC-LCPP 1012
Query: 2059 RWV-LIPQEGCLECDS 2073
+ Q ECDS
Sbjct: 1013 GFTGSYCQHVVNECDS 1028
Score = 57.2 bits (132), Expect = 1e-06
Identities = 91/361 (25%), Positives = 130/361 (36%), Gaps = 77/361 (21%)
Query: 1735 ECQCPRAYRGLSCEQ--------CAEGHYRLPSGFCVPCQC--NGHSDQC--DVN----- 1777
+C+CP + G SC+Q CA G LP C C + H C DVN
Sbjct: 126 KCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK 185
Query: 1778 TGICLN--CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C + N +G + C + + G R + C+ P P N +C
Sbjct: 186 PRLCRHGGTCHNEVGSYRCVCRATHTGP---NCERPYVPCS---PSPCQNGG-TC--RPT 236
Query: 1836 GSLI-SCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPC--NCSGNINPQDP 1888
G + C C PG+ G CE C Y PC +G +D
Sbjct: 237 GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWTGQYCTEDV 296
Query: 1889 GSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDST 1943
C + C C N G C +C G+ G+ +C + C F A C
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNC-VCVNGWTGEDCSENIDDCASAAC--FHGATCHDR 353
Query: 1944 TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRC 1997
+ C C G G C LN PCN E + CD + NG+ C C
Sbjct: 354 VASFYCECPHGRTGLLCH--------LNDACISNPCN-----EGSNCDTNPVNGKAICTC 400
Query: 1998 AKGVTGKQC----DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G TG C D+C+ G + C+H G + + + +C+CL G G +C
Sbjct: 401 PSGYTGPACSQDVDECSLG-----ANPCEH----AGKCINTL--GSFECQCLQGYTGPRC 449
Query: 2054 D 2054
+
Sbjct: 450 E 450
Score = 57.2 bits (132), Expect = 1e-06
Identities = 83/339 (24%), Positives = 117/339 (34%), Gaps = 51/339 (15%)
Query: 1733 VEECQCPRAYRGLSCEQCAEGHYRLP---SGFC------VPCQC-NGHSD-QCDVNTGIC 1781
+ C CP+ Y G +C+ P G C C+C +G + CDV + C
Sbjct: 1043 LHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC 1102
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFA-LSCDLSENGSLIS 1840
A D C HG V + C C Y + L + S +
Sbjct: 1103 EVAAQRQGVDVARLCQ---HGGLCVDAG-NTHHCRCQAGYTGSYCEDLVDECSPSPCQNG 1158
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC-DSINGDCL 1899
C GG C+ C AGY+G+ ++ D C C Q+ G+C D N
Sbjct: 1159 ATCTDYLGGYSCK-CVAGYHGVNCSEEI---DECLSHPC------QNGGTCLDLPNTYKC 1208
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTG--TCVCRPGVIGEK 1957
C T G C + C F C G +C C PG +GE+
Sbjct: 1209 SCPRGTQGVHCEINVDDCNPPVDPVSRSPKC----FNNGTCVDQVGGYSCTCPPGFVGER 1264
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
C+ +N L PC+ Q +D C C G TG++C+
Sbjct: 1265 CE------GDVNECLS-NPCDARGTQNCVQRVND-FHCECRAGHTGRRCESVI------- 1309
Query: 2018 KDGCDHCNCNTGYSVGFMCN-ATG-QCECLPGVIGEKCD 2054
+GC C G + N A G C+C G G C+
Sbjct: 1310 -NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1347
Score = 54.8 bits (126), Expect = 6e-06
Identities = 77/304 (25%), Positives = 105/304 (34%), Gaps = 56/304 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHS-DQCDVNTGICLNCADNTIGDHC 1793
C+CP + GL C+ +PS C V Q G + + G+C++ A NT HC
Sbjct: 1084 CECPSGWTGLYCD--------VPSVSCEVAAQRQGVDVARLCQHGGLCVD-AGNT--HHC 1132
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C +GY G +C P P N A D SC C GY G C
Sbjct: 1133 R-CQAGYTGSYCEDLVDEC------SPSPCQNGATCTDYLGG---YSCKCVAGYHGVNCS 1182
Query: 1854 Y---------CAAG--YYGIPEDTDLHTGDYCKPCNCSGNIN----PQDPGSCDSINGDC 1898
C G +P + +C N++ P DP S +
Sbjct: 1183 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1242
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGT--CVCRPGVI 1954
CV+ G +C C PGF G+ C + CD G +C C CR G
Sbjct: 1243 GTCVDQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 1301
Query: 1955 GEKCDRCAPDHWGL------------NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G +C+ G NT G C C E C++D C + +
Sbjct: 1302 GRRCESVINGCKGKPCKNGGTCAVASNTARGFI-CKCPAGFEGATCENDARTCGSLRCLN 1360
Query: 2003 GKQC 2006
G C
Sbjct: 1361 GGTC 1364
Score = 54.0 bits (124), Expect = 1e-05
Identities = 69/249 (27%), Positives = 89/249 (35%), Gaps = 41/249 (16%)
Query: 1315 SPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
+P G CR+++ + + G CD + + E E N CK G C+ CR
Sbjct: 723 NPCVHGACRDSLNGYKCDCDPGWSGTNCD-INNNECESNPCVNGGTCKDMTSGIVCT-CR 780
Query: 1375 TGYYGFPNCR---------PCHCPSTAICDDNGM-CICPKNVEGENCD----RCKPYTF- 1419
G+ G PNC+ PC T I D G C C G C+ C P
Sbjct: 781 EGFSG-PNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 1420 NFDVQRGCDD-----CNCNPLGVVGNQLQCEADSGKCA---CR-----ENVRGRVCDHCV 1466
N R +D C C G G CE D +C CR +N G HC
Sbjct: 840 NGGECRQSEDYESFSCVCPTAGAKGQT--CEVDINECVLSPCRHGASCQNTHGXYRCHCQ 897
Query: 1467 PGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQD 1520
G+ DC C+ G+ D NTA C C RG C+ E +
Sbjct: 898 AGYSGRNCETDIDDCRPNPCHNGGSCTDGI--NTAFCDCLPGFRGTFCEEDINECASDPC 955
Query: 1521 DNPDGCTKC 1529
N CT C
Sbjct: 956 RNGANCTDC 964
Score = 51.6 bits (118), Expect = 5e-05
Identities = 86/351 (24%), Positives = 117/351 (33%), Gaps = 65/351 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
+C CPR +G+ CE + C P S +C N G C++ +G +
Sbjct: 1207 KCSCPRGTQGVHCEINVDD--------CNPPVDPVSRSPKC-FNNGTCVD----QVGGYS 1253
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G+ G+ G +CL C N C N C C+ G+ G RCE
Sbjct: 1254 CTCPPGFVGERCEGDVNECLSNPCDARGTQN-----CVQRVND--FHCECRAGHTGRRCE 1306
Query: 1854 YCAAGYYGIP--------EDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLK---C 1901
G G P ++ G CK P G D +C S+ CL C
Sbjct: 1307 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR--CLNGGTC 1364
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKNCTACICDE--FGMADCDSTTGT----CVCRPGVIG 1955
++ C LC F G + C+ + C+ T+ + C+C G
Sbjct: 1365 ISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 1423
Query: 1956 EKCDRCAPDHWGLNTGLGCTP-----------CN-------CGIASESTQCDDDNGQCRC 1997
C +G G P C C + + C D G C
Sbjct: 1424 LLC-HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSL 1482
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDG-CD-HCNCNTGYSVGFMC-NATGQCECL 2045
K C Q + W Y DG CD CN GF C A GQC L
Sbjct: 1483 NFNDPWKNCTQ-SLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPL 1532
Score = 50.0 bits (114), Expect = 2e-04
Identities = 86/350 (24%), Positives = 122/350 (34%), Gaps = 51/350 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVPCQCNGHSDQCDVN-TGICLNCADNTIG 1790
EC C + G +CE+ + G+ G CV N ++ C TG C ++
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGACVD-GVNTYNCPCPPEWTG--QYCTEDV-- 296
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
D C+ + T C C + D SEN + C + GA
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGE------DCSEN--IDDCASAACFHGA 348
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAA 1909
C A +Y E TG C N + NP + GS CD+ N G A
Sbjct: 349 TCHDRVASFYC--ECPHGRTGLLCH-LNDACISNPCNEGSNCDT---------NPVNGKA 396
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C G+ G A S++ C G C+ G C+ G +C +C + G
Sbjct: 397 ICTCPSGYTGPAC-SQDVDEC---SLGANPCEHA-GKCINTLGSF--EC-QCLQGYTGPR 448
Query: 1970 TGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQC----DQCAAGFWNYTKDGCD- 2022
+ C C D G QC C G G C D+CA+ + D
Sbjct: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
Query: 2023 ----HCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEG 2067
C C TG++ G +C +C P G KC P + + EG
Sbjct: 509 INEFQCECPTGFT-GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEG 557
Score = 45.6 bits (103), Expect = 0.003
Identities = 66/240 (27%), Positives = 87/240 (36%), Gaps = 47/240 (19%)
Query: 1877 CNCSGN-INP--QDPGSCDSI---NGDCLKCVNN--TAGAACNLCAPGFYGDAIFSKNCT 1928
C C G + P QDP C S N V+ A AC+ CA GF G +
Sbjct: 46 CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACS-CALGFSGPLCLTPLDN 104
Query: 1929 ACI---CDEFGMADCDSTTG-TCVCRPGVIGEKC---DRCAPDHWGLNTGLGCTP----- 1976
AC+ C G D + T C C PG G+ C D CA + G C P
Sbjct: 105 ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA--NGGQCLPFEASY 162
Query: 1977 -CNCGIASESTQCDDDNGQCR-----CAKGVT-----GKQCDQCAAGFWNYTKDGCDH-- 2023
C+C + C D +C C G T G C A +T C+
Sbjct: 163 ICHCPPSFHGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRA---THTGPNCERPY 219
Query: 2024 --CN---CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDAL 2078
C+ C G + + T +C CLPG G+ C+ E P C +C D +
Sbjct: 220 VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE---ENIDDCPGNNCKNGGACVDGV 276
Score = 45.2 bits (102), Expect = 0.005
Identities = 50/197 (25%), Positives = 67/197 (34%), Gaps = 28/197 (14%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-----CDDNGMCICPKNVEGEN 1410
GG C PN +C G + N C+ P + C +NG C+ V G +
Sbjct: 1196 GGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV--DQVGGYS 1253
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQC--EADSGKCACRENVRGRVCDHCVPG 1468
C C P + ++C NP G Q C + C CR GR C+ + G
Sbjct: 1254 CT-CPPGFVGERCEGDVNECLSNPCDARGTQ-NCVQRVNDFHCECRAGHTGRRCESVING 1311
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQ---CYCKTNVRGQACDTCKEEYFNLQDDNPDG 1525
C C GT NTA+ C C G C+ +L+ N
Sbjct: 1312 ------CKGKPCKNGGTC--AVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1363
Query: 1526 CTK------CFCFGKTT 1536
C C C G T
Sbjct: 1364 CISGPRSPTCLCLGPFT 1380
Score = 43.6 bits (98), Expect = 0.014
Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 27/187 (14%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRP--CHCP 1389
C C G T C +C P G TC+ C GY+G NC C
Sbjct: 1132 CRCQ-AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGV-NCSEEIDECL 1189
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
S C + G C+ N +C R T + DDCN P+ V +C ++G
Sbjct: 1190 SHP-CQNGGTCLDLPNTYKCSCPRG---TQGVHCEINVDDCN-PPVDPVSRSPKC-FNNG 1243
Query: 1450 KCACRENVRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
C + V G C C PG +C C+ GT V N C C+
Sbjct: 1244 TCV--DQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1300
Query: 1504 RGQACDT 1510
G+ C++
Sbjct: 1301 TGRRCES 1307
Score = 43.2 bits (97), Expect = 0.018
Identities = 51/183 (27%), Positives = 64/183 (34%), Gaps = 35/183 (19%)
Query: 1361 CKPNVIGRTCSACRTGYYG------FPNC--RPCHCPSTAICDDNG-MCICPKNVEGENC 1411
CK V TC CR GY G C +PC T DN +C C K G NC
Sbjct: 580 CKDGVATFTC-LCRPGYTGHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNC 638
Query: 1412 DRCKPYTFNFDVQRG-CDD------CNCNPLGVVGNQLQCEADSGKCA---------CRE 1455
+ + G C D C C P G G+ C ++ +CA C +
Sbjct: 639 EINLDDCASSPCDSGTCLDKIDGYECACEP-GYTGS--MCNSNIDECAGNPCHNGGTCED 695
Query: 1456 NVRGRVCDHCVPGHYAFPDCYQ--CTCNRHGTTYDVC--DQNTAQCYCKTNVRGQACDTC 1511
+ G C C P Y P C CN + + C N +C C G CD
Sbjct: 696 GINGFTC-RC-PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN 753
Query: 1512 KEE 1514
E
Sbjct: 754 NNE 756
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/265 (22%), Positives = 87/265 (32%), Gaps = 55/265 (20%)
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C C GF GP C L + C+ C G+ + KC C + G
Sbjct: 87 CSCALGFSGPLCLTPL----------DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
C Q P C S C +G + + +CHC +F G TCR+
Sbjct: 137 SCQQADP-------CASNPC-ANGGQCLPFEASYICHCPPSFHG---PTCRQD------V 179
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
EC PR + C + C C+ G C + Y P C C
Sbjct: 180 NECGQKPR-LCRHGGTCHNEVGSYRCVCRATHTGPNCE---------RPYVP--CSPSPC 227
Query: 696 NLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSID 755
GT G + +C C + C++ +D C +C GG+
Sbjct: 228 QNGGTCRPTG---DVTHECACLPGFTGQNCEENID-----------DCPGNNCKNGGACV 273
Query: 756 NNCDKTTGQCHCHSRVEGRRCDQPI 780
+ + T C C G+ C + +
Sbjct: 274 DGVN--TYNCPCPPEWTGQYCTEDV 296
Score = 42.7 bits (96), Expect = 0.024
Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 27/152 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGENC- 1411
G +C C+P G C++ G PCH T C+D NG C CP+ C
Sbjct: 661 GYECACEPGYTGSMCNSNIDECAG----NPCHNGGT--CEDGINGFTCRCPEGYHDPTCL 714
Query: 1412 DRCKPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
N V C D C+C+P G G C+ ++ +C V G C
Sbjct: 715 SEVNECNSNPCVHGACRDSLNGYKCDCDP-GWSGT--NCDINNNECESNPCVNGGTCKDM 771
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
G CTC R G + C N +C
Sbjct: 772 TSG-------IVCTC-REGFSGPNCQTNINEC 795
Score = 39.1 bits (87), Expect = 0.30
Identities = 64/257 (24%), Positives = 87/257 (33%), Gaps = 33/257 (12%)
Query: 1299 YTREFIEQCASYNYYISPNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTF-G 1356
+ E I +CAS P G C + + S T +G C+ E + F G
Sbjct: 942 FCEEDINECAS-----DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG 996
Query: 1357 GQCPCKPNVIGRTCSACRTGYYG---FPNC--RPCHCPSTAICDDNGM--CICPKNVEGE 1409
G C N C TG Y C RPC T D G+ C CP+ G
Sbjct: 997 GTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQ-DGRGLHRCTCPQGYTGP 1055
Query: 1410 NCDRCKPYTFNFDVQRGCDDCNCNPLGV---VGNQLQCEADSGKCACRENVRGRVCDHCV 1466
NC ++ CD C G Q +CE SG +V C+ V
Sbjct: 1056 NCQ---------NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE--V 1104
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
D + C G D NT C C+ G C+ +E N C
Sbjct: 1105 AAQRQGVDVARL-CQHGGLCVDA--GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 1161
Query: 1527 TKCFCFGKTTRCSSSYY 1543
T + G + +C + Y+
Sbjct: 1162 TD-YLGGYSCKCVAGYH 1177
Score = 34.3 bits (75), Expect = 8.4
Identities = 51/192 (26%), Positives = 62/192 (32%), Gaps = 28/192 (14%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
RP C GS NT C C P G C P +C C D+
Sbjct: 913 RPNPCHNGGSCTDGINT--AFCDCLPGFRGTFCEEDINECASDPCRNGANCTD---CVDS 967
Query: 1398 GMCICPKNVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQ---CEA 1446
C CP G +C+ P G C D C C P G G+ Q E
Sbjct: 968 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPP-GFTGSYCQHVVNEC 1026
Query: 1447 DSGKCACRENVR-GRVCDHCV-PGHYAFPDC----YQC---TCNRHGTTYDVCDQNTAQC 1497
DS C + GR C P Y P+C + C C G + Q +C
Sbjct: 1027 DSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ--YRC 1084
Query: 1498 YCKTNVRGQACD 1509
C + G CD
Sbjct: 1085 ECPSGWTGLYCD 1096
>D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.
Length = 2854
Score = 90.2 bits (214), Expect = 1e-16
Identities = 69/254 (27%), Positives = 101/254 (39%), Gaps = 32/254 (12%)
Query: 427 CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD----CTCKSKYSGRTC 481
C ++ SC C+ GYY C N C+ N S K + C C Y G C
Sbjct: 1739 CSNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYC 1797
Query: 482 NQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
C G++ +PTC PCNCD S G +P C+ SG+C CK P
Sbjct: 1798 ETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD-CNKTSGECHCKENHYRPPGSPT----- 1851
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
C+ C+C PTGS S C DG+C C G QCD+C + + +
Sbjct: 1852 ---------CLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCD---NPFAEVTTNG 1899
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C+V+ + G+ ++ F C + + A C+ + + C S
Sbjct: 1900 CEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFG-TAVRHCDEHRGWLPPNLFNCTS 1958
Query: 655 VPAGELCQCKDRVQ 668
+ EL +R+Q
Sbjct: 1959 ITFSELKGFAERLQ 1972
Score = 86.2 bits (204), Expect = 2e-15
Identities = 48/162 (29%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C ++ + +C+ C P YY G + PC+ + CEC P +
Sbjct: 1739 CSNDWDSYSCS-CDPGYY---GDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG 1794
Query: 388 PDCSS-----CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P C + C G++ +P C PC C+++ C T G C CK N+
Sbjct: 1795 PYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPG------ 1848
Query: 443 YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
SP C C+C GS+S VCD G C CK GR C++C
Sbjct: 1849 --SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1888
Score = 80.2 bits (189), Expect = 1e-13
Identities = 57/190 (30%), Positives = 80/190 (42%), Gaps = 27/190 (14%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG 412
+ ++V Q C + C S C ++ CS C GY+ NC C+LN
Sbjct: 1714 ESINVEQGCSLPDPCDSNPCPANS---YCSNDWDSYSCS-CDPGYYG-DNCTN-VCDLNP 1767
Query: 413 TEGEH-CT-----PTDGLCPCKYNYAGKSCEI-----CEDGYYS-PECKNCECNTVGSVS 460
E + CT P C C NY G CE C G++ P C C C+
Sbjct: 1768 CEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFD 1827
Query: 461 YVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
C+K +G+C CK + + PTC C+C +G+ +CD GQC CK
Sbjct: 1828 PDCNKTSGECHCKENHYRPPGS---------PTCLLCDCYPTGSLSRVCDPEDGQCPCKP 1878
Query: 521 GFGGPRCDQC 530
G G +CD+C
Sbjct: 1879 GVIGRQCDRC 1888
Score = 71.7 bits (168), Expect = 5e-11
Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 15/177 (8%)
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDE-KRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
S +WD +SC C+ + CT +++ + S+ G C N G
Sbjct: 1740 SNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG---P 1795
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAYGY 397
C +P + W C PC CD +C + SG C C+ P S
Sbjct: 1796 YCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGS------ 1849
Query: 398 FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
P C C C G+ C P DG CPCK G+ C+ C++ + CE N
Sbjct: 1850 ---PTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVN 1903
Score = 70.1 bits (164), Expect = 1e-10
Identities = 73/276 (26%), Positives = 99/276 (35%), Gaps = 52/276 (18%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
C+ P P SN + S + SC+C PGY G C DL+ ++
Sbjct: 1722 CSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNVC----------DLNPCEHQ 1771
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-----CAPGFYGDAIFSKNCTA 1929
C P P +G +C N G C C G++G C
Sbjct: 1772 SVCTRK----PSAP------HGYTCECPPNYLGPYCETRIDQPCPRGWWGHP----TCGP 1817
Query: 1930 CICD-EFGM-ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASEST 1986
C CD G DC+ T+G C C+ +H+ C C+C S S
Sbjct: 1818 CNCDVSKGFDPDCNKTSGECHCKE------------NHYRPPGSPTCLLCDCYPTGSLSR 1865
Query: 1987 QCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT----- 2039
CD ++GQC C GV G+QCD+C F T +GC+ + +C G T
Sbjct: 1866 VCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLP 1925
Query: 2040 GQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C G G C E +P C S T
Sbjct: 1926 AAAPCPKGSFGTAVRHCDEHRGWLP-PNLFNCTSIT 1960
Score = 67.7 bits (158), Expect = 7e-10
Identities = 53/195 (27%), Positives = 78/195 (40%), Gaps = 30/195 (15%)
Query: 592 SCNCDVSGSIGSTCDDNGL---CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTAS 648
S N + S+ CD N +C +++D C +C +Y C+ +P +
Sbjct: 1715 SINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSC-SCDPGYYGDNCTNVCDLNPCEHQSV 1773
Query: 649 FAGCGSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S P G C+C G C C +W +P C CNC+++ +
Sbjct: 1774 CTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWG----HPT-CGPCNCDVSKGFDP 1828
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
CN SG+C CK++ YR + C CDC GS+ CD G
Sbjct: 1829 --DCNKTSGECHCKEN------------HYRPPGSPT--CLLCDCYPTGSLSRVCDPEDG 1872
Query: 764 QCHCHSRVEGRRCDQ 778
QC C V GR+CD+
Sbjct: 1873 QCPCKPGVIGRQCDR 1887
Score = 67.3 bits (157), Expect = 1e-09
Identities = 60/199 (30%), Positives = 89/199 (44%), Gaps = 37/199 (18%)
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCD---- 606
P S C A+ C+ ++ C C PGYY +C + CD++ S C
Sbjct: 1725 PDPCDSNPCPANSYCS--NDWDSYSCS-CDPGYYG-DNCTNV-CDLNPCEHQSVCTRKPS 1779
Query: 607 -DNGL-CHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
+G C C N+ G C+T C ++ +P C CNCD V+ F + +GE
Sbjct: 1780 APHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCD---VSKGFDPDCNKTSGE 1836
Query: 660 LCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
C CK+ N +P +P C C+C G+L+ + C+ + GQC CK
Sbjct: 1837 -CHCKE-------NHYRP------PGSPT-CLLCDCYPTGSLSRV--CDPEDGQCPCKPG 1879
Query: 720 VGERQCDQCLDGFYRLQTN 738
V RQCD+C + F + TN
Sbjct: 1880 VIGRQCDRCDNPFAEVTTN 1898
Score = 66.1 bits (154), Expect = 2e-09
Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 25/159 (15%)
Query: 1369 TCSACRTGYYGFPNC------RPCH----CPSTAICDDNGMCICPKNVEGENCDRC--KP 1416
+CS C GYYG NC PC C C CP N G C+ +P
Sbjct: 1747 SCS-CDPGYYG-DNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQP 1804
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C CNC+ G C SG+C C+EN + PG P C
Sbjct: 1805 CPRGWWGHPTCGPCNCDVSK--GFDPDCNKTSGECHCKEN------HYRPPGS---PTCL 1853
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C G+ VCD QC CK V G+ CD C +
Sbjct: 1854 LCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPF 1892
Score = 64.1 bits (149), Expect = 9e-09
Identities = 38/115 (33%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 1356 GGQCPCKPNVIGRTCSA-----CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGEN 1410
G C C PN +G C C G++G P C PC+C + D + C K GE
Sbjct: 1783 GYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD----CNK-TSGE- 1836
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
C CK + C C+C P G + C+ + G+C C+ V GR CD C
Sbjct: 1837 C-HCKENHYRPPGSPTCLLCDCYPTGSLSR--VCDPEDGQCPCKPGVIGRQCDRC 1888
Score = 62.9 bits (146), Expect = 2e-08
Identities = 54/170 (31%), Positives = 69/170 (40%), Gaps = 44/170 (25%)
Query: 1811 DCLICACPMPYPSNNFALSCDLS--ENGSL----------ISCNCQPGYGGARCEY---- 1854
D C+C Y +N CDL+ E+ S+ +C C P Y G CE
Sbjct: 1744 DSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQ 1803
Query: 1855 -CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
C G++G P C PCNC + DP C+ +G+C C N +
Sbjct: 1804 PCPRGWWGHPT---------CGPCNCDVS-KGFDP-DCNKTSGEC-HCKEN------HYR 1845
Query: 1914 APGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRC 1961
PG S C C C G CD G C C+PGVIG +CDRC
Sbjct: 1846 PPG-------SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1888
Score = 51.6 bits (118), Expect = 5e-05
Identities = 40/125 (32%), Positives = 56/125 (44%), Gaps = 27/125 (21%)
Query: 1736 CQCPRAYRGLSCEQ-----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
C+CP Y G CE C G + P+ C PC C DV+ G +C N
Sbjct: 1786 CECPPNYLGPYCETRIDQPCPRGWWGHPT--CGPCNC-------DVSKGFDPDC--NKTS 1834
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C ++ G+P CL+C C YP+ + + CD E+G C C+PG G
Sbjct: 1835 GECH-CKENHYRPP--GSPT-CLLCDC---YPTGSLSRVCD-PEDGQ---CPCKPGVIGR 1883
Query: 1851 RCEYC 1855
+C+ C
Sbjct: 1884 QCDRC 1888
Score = 50.0 bits (114), Expect = 2e-04
Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA----IC 1394
PC CD + +CN G+C CK N G P C C C T +C
Sbjct: 1817 PCNCDVSKGFDPDCNKTSGECHCKENHYRPP---------GSPTCLLCDCYPTGSLSRVC 1867
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D ++G C C V G CDRC
Sbjct: 1868 DPEDGQCPCKPGVIGRQCDRC 1888
Score = 34.7 bits (76), Expect = 6.4
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTG--TCVCRPGVIGEK 1957
++ G C C PGF GD ++ C + C G C S G TC+CR G GE
Sbjct: 1197 IHPVGGLRCR-CPPGFTGDYCETEVDLCYSRPCGPHGR--CRSREGGYTCLCRDGYTGEH 1253
Query: 1958 CD 1959
C+
Sbjct: 1254 CE 1255
Score = 34.3 bits (75), Expect = 8.4
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHC-- 418
C+C P F+ CE E C RP C S GY C C +G GEHC
Sbjct: 1205 CRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGY-------TCLCR-DGYTGEHCEV 1256
Query: 419 TPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
+ G C G +C G + +C
Sbjct: 1257 SARSGRCTPGVCKNGGTCVNLLVGGFKCDC 1286
>AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 2 (flamingo homolog, Drosophila) protein.
Length = 2923
Score = 90.2 bits (214), Expect = 1e-16
Identities = 69/254 (27%), Positives = 101/254 (39%), Gaps = 32/254 (12%)
Query: 427 CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD----CTCKSKYSGRTC 481
C ++ SC C+ GYY C N C+ N S K + C C Y G C
Sbjct: 1808 CSNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYC 1866
Query: 482 NQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
C G++ +PTC PCNCD S G +P C+ SG+C CK P
Sbjct: 1867 ETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD-CNKTSGECHCKENHYRPPGSPT----- 1920
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
C+ C+C PTGS S C DG+C C G QCD+C + + +
Sbjct: 1921 ---------CLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCD---NPFAEVTTNG 1968
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C+V+ + G+ ++ F C + + A C+ + + C S
Sbjct: 1969 CEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFG-TAVRHCDEHRGWLPPNLFNCTS 2027
Query: 655 VPAGELCQCKDRVQ 668
+ EL +R+Q
Sbjct: 2028 ITFSELKGFAERLQ 2041
Score = 86.2 bits (204), Expect = 2e-15
Identities = 48/162 (29%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C ++ + +C+ C P YY G + PC+ + CEC P +
Sbjct: 1808 CSNDWDSYSCS-CDPGYY---GDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG 1863
Query: 388 PDCSS-----CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P C + C G++ +P C PC C+++ C T G C CK N+
Sbjct: 1864 PYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPG------ 1917
Query: 443 YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
SP C C+C GS+S VCD G C CK GR C++C
Sbjct: 1918 --SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 80.2 bits (189), Expect = 1e-13
Identities = 57/190 (30%), Positives = 80/190 (42%), Gaps = 27/190 (14%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG 412
+ ++V Q C + C S C ++ CS C GY+ NC C+LN
Sbjct: 1783 ESINVEQGCSLPDPCDSNPCPANS---YCSNDWDSYSCS-CDPGYYG-DNCTN-VCDLNP 1836
Query: 413 TEGEH-CT-----PTDGLCPCKYNYAGKSCEI-----CEDGYYS-PECKNCECNTVGSVS 460
E + CT P C C NY G CE C G++ P C C C+
Sbjct: 1837 CEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFD 1896
Query: 461 YVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
C+K +G+C CK + + PTC C+C +G+ +CD GQC CK
Sbjct: 1897 PDCNKTSGECHCKENHYRPPGS---------PTCLLCDCYPTGSLSRVCDPEDGQCPCKP 1947
Query: 521 GFGGPRCDQC 530
G G +CD+C
Sbjct: 1948 GVIGRQCDRC 1957
Score = 71.7 bits (168), Expect = 5e-11
Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 15/177 (8%)
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDE-KRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
S +WD +SC C+ + CT +++ + S+ G C N G
Sbjct: 1809 SNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG---P 1864
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAYGY 397
C +P + W C PC CD +C + SG C C+ P S
Sbjct: 1865 YCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGS------ 1918
Query: 398 FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
P C C C G+ C P DG CPCK G+ C+ C++ + CE N
Sbjct: 1919 ---PTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVN 1972
Score = 70.1 bits (164), Expect = 1e-10
Identities = 73/276 (26%), Positives = 99/276 (35%), Gaps = 52/276 (18%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
C+ P P SN + S + SC+C PGY G C DL+ ++
Sbjct: 1791 CSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNVC----------DLNPCEHQ 1840
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-----CAPGFYGDAIFSKNCTA 1929
C P P +G +C N G C C G++G C
Sbjct: 1841 SVCTRK----PSAP------HGYTCECPPNYLGPYCETRIDQPCPRGWWGHP----TCGP 1886
Query: 1930 CICD-EFGM-ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASEST 1986
C CD G DC+ T+G C C+ +H+ C C+C S S
Sbjct: 1887 CNCDVSKGFDPDCNKTSGECHCKE------------NHYRPPGSPTCLLCDCYPTGSLSR 1934
Query: 1987 QCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT----- 2039
CD ++GQC C GV G+QCD+C F T +GC+ + +C G T
Sbjct: 1935 VCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLP 1994
Query: 2040 GQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C G G C E +P C S T
Sbjct: 1995 AAAPCPKGSFGTAVRHCDEHRGWLP-PNLFNCTSIT 2029
Score = 67.7 bits (158), Expect = 7e-10
Identities = 53/195 (27%), Positives = 78/195 (40%), Gaps = 30/195 (15%)
Query: 592 SCNCDVSGSIGSTCDDNGL---CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTAS 648
S N + S+ CD N +C +++D C +C +Y C+ +P +
Sbjct: 1784 SINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSC-SCDPGYYGDNCTNVCDLNPCEHQSV 1842
Query: 649 FAGCGSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S P G C+C G C C +W +P C CNC+++ +
Sbjct: 1843 CTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWG----HPT-CGPCNCDVSKGFDP 1897
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
CN SG+C CK++ YR + C CDC GS+ CD G
Sbjct: 1898 --DCNKTSGECHCKEN------------HYRPPGSPT--CLLCDCYPTGSLSRVCDPEDG 1941
Query: 764 QCHCHSRVEGRRCDQ 778
QC C V GR+CD+
Sbjct: 1942 QCPCKPGVIGRQCDR 1956
Score = 67.3 bits (157), Expect = 1e-09
Identities = 60/199 (30%), Positives = 89/199 (44%), Gaps = 37/199 (18%)
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCD---- 606
P S C A+ C+ ++ C C PGYY +C + CD++ S C
Sbjct: 1794 PDPCDSNPCPANSYCS--NDWDSYSCS-CDPGYYG-DNCTNV-CDLNPCEHQSVCTRKPS 1848
Query: 607 -DNGL-CHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
+G C C N+ G C+T C ++ +P C CNCD V+ F + +GE
Sbjct: 1849 APHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCD---VSKGFDPDCNKTSGE 1905
Query: 660 LCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
C CK+ N +P +P C C+C G+L+ + C+ + GQC CK
Sbjct: 1906 -CHCKE-------NHYRP------PGSPT-CLLCDCYPTGSLSRV--CDPEDGQCPCKPG 1948
Query: 720 VGERQCDQCLDGFYRLQTN 738
V RQCD+C + F + TN
Sbjct: 1949 VIGRQCDRCDNPFAEVTTN 1967
Score = 66.1 bits (154), Expect = 2e-09
Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 25/159 (15%)
Query: 1369 TCSACRTGYYGFPNC------RPCH----CPSTAICDDNGMCICPKNVEGENCDRC--KP 1416
+CS C GYYG NC PC C C CP N G C+ +P
Sbjct: 1816 SCS-CDPGYYG-DNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQP 1873
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C CNC+ G C SG+C C+EN + PG P C
Sbjct: 1874 CPRGWWGHPTCGPCNCDVSK--GFDPDCNKTSGECHCKEN------HYRPPGS---PTCL 1922
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C G+ VCD QC CK V G+ CD C +
Sbjct: 1923 LCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPF 1961
Score = 64.1 bits (149), Expect = 9e-09
Identities = 38/115 (33%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 1356 GGQCPCKPNVIGRTCSA-----CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGEN 1410
G C C PN +G C C G++G P C PC+C + D + C K GE
Sbjct: 1852 GYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD----CNK-TSGE- 1905
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
C CK + C C+C P G + C+ + G+C C+ V GR CD C
Sbjct: 1906 C-HCKENHYRPPGSPTCLLCDCYPTGSLSR--VCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 62.9 bits (146), Expect = 2e-08
Identities = 54/170 (31%), Positives = 69/170 (40%), Gaps = 44/170 (25%)
Query: 1811 DCLICACPMPYPSNNFALSCDLS--ENGSL----------ISCNCQPGYGGARCEY---- 1854
D C+C Y +N CDL+ E+ S+ +C C P Y G CE
Sbjct: 1813 DSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQ 1872
Query: 1855 -CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
C G++G P C PCNC + DP C+ +G+C C N +
Sbjct: 1873 PCPRGWWGHPT---------CGPCNCDVS-KGFDP-DCNKTSGEC-HCKEN------HYR 1914
Query: 1914 APGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRC 1961
PG S C C C G CD G C C+PGVIG +CDRC
Sbjct: 1915 PPG-------SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 51.6 bits (118), Expect = 5e-05
Identities = 40/125 (32%), Positives = 56/125 (44%), Gaps = 27/125 (21%)
Query: 1736 CQCPRAYRGLSCEQ-----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
C+CP Y G CE C G + P+ C PC C DV+ G +C N
Sbjct: 1855 CECPPNYLGPYCETRIDQPCPRGWWGHPT--CGPCNC-------DVSKGFDPDC--NKTS 1903
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C ++ G+P CL+C C YP+ + + CD E+G C C+PG G
Sbjct: 1904 GECH-CKENHYRPP--GSPT-CLLCDC---YPTGSLSRVCD-PEDGQ---CPCKPGVIGR 1952
Query: 1851 RCEYC 1855
+C+ C
Sbjct: 1953 QCDRC 1957
Score = 50.0 bits (114), Expect = 2e-04
Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA----IC 1394
PC CD + +CN G+C CK N G P C C C T +C
Sbjct: 1886 PCNCDVSKGFDPDCNKTSGECHCKENHYRPP---------GSPTCLLCDCYPTGSLSRVC 1936
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D ++G C C V G CDRC
Sbjct: 1937 DPEDGQCPCKPGVIGRQCDRC 1957
Score = 34.7 bits (76), Expect = 6.4
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTG--TCVCRPGVIGEK 1957
++ G C C PGF GD ++ C + C G C S G TC+CR G GE
Sbjct: 1266 IHPVGGLRCR-CPPGFTGDYCETEVDLCYSRPCGPHGR--CRSREGGYTCLCRDGYTGEH 1322
Query: 1958 CD 1959
C+
Sbjct: 1323 CE 1324
Score = 34.3 bits (75), Expect = 8.4
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHC-- 418
C+C P F+ CE E C RP C S GY C C +G GEHC
Sbjct: 1274 CRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGY-------TCLCR-DGYTGEHCEV 1325
Query: 419 TPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
+ G C G +C G + +C
Sbjct: 1326 SARSGRCTPGVCKNGGTCVNLLVGGFKCDC 1355
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 90.2 bits (214), Expect = 1e-16
Identities = 157/639 (24%), Positives = 222/639 (34%), Gaps = 108/639 (16%)
Query: 211 DPTVTRRYFYSIKDISIGGRCM--CNGHADTCEPADPAGNLNILVCRCQHNTC--GPQCN 266
DPT + + G C NG+ C+P N +I C+ N C G C
Sbjct: 710 DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCK 769
Query: 267 KCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCL 326
SG + + FS NC + EC +P +++ D+ G KC
Sbjct: 770 DMTSGI------VCTCREGFSGP--NCQTNINECASNPCLNKGTCIDDV-----AGYKC- 815
Query: 327 NCQHNTEGINCN----KCRPTYYRPYGK-RWDELDVCQPCQCDPHFSTGN-CEEESGRCE 380
NC G C C P+ R G+ R E C C + G CE + C
Sbjct: 816 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECV 875
Query: 381 CRPEFQPPDCSS--------CAYGYF------DYPNCKPCTCNLNGTEGEHCTP--TDGL 424
P C + C GY D +C+P C+ G+ CT
Sbjct: 876 LSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS----CTDGINTAF 931
Query: 425 CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
C C + G CE ED EC + C + + D T CTC + +SG C
Sbjct: 932 CDCLPGFRGTFCE--ED---INECASDPCRNGANCTDCVDSYT--CTCPAGFSGIHCEN- 983
Query: 485 QAGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQ--VLGR 541
N P C +C GT D ++ C+C GF G C ++ + +LG
Sbjct: 984 -----NTPDCTESSCFNGGT---CVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGG 1035
Query: 542 E----RQCVPCNCDPTGSTSTSC-SADGKCNCLTNFGGAQCDQ--------CSPGYYK-Y 587
R C C P G T +C + C+ G +C Q C G+ Y
Sbjct: 1036 TCQDGRGLHRCTC-PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLY 1094
Query: 588 PDCLSCNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
D S +C+V+ + C GLC N +C Y +EC+ P
Sbjct: 1095 CDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP 1154
Query: 643 --RGVTAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
G T + + G C V C + + + + C+ L N + C C
Sbjct: 1155 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS-CPRG 1213
Query: 697 LAGTLNSLGA--CN------TKSGQC----VCKQHVGERQCDQCLDGFYRLQTN-DVFGC 743
G + CN ++S +C C VG C C GF + DV C
Sbjct: 1214 TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT-CPPGFVGERCEGDVNEC 1272
Query: 744 TECDCDIGGSIDNNCDKTTGQCHCHSRV--EGRRCDQPI 780
CD G+ NC + HC R GRRC+ I
Sbjct: 1273 LSNPCDARGT--QNCVQRVNDFHCECRAGHTGRRCESVI 1309
Score = 87.8 bits (208), Expect = 6e-16
Identities = 142/591 (24%), Positives = 190/591 (32%), Gaps = 99/591 (16%)
Query: 239 TCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWDRF--SCEP--- 290
TC+ D N +C C T GP C C+ D + +CEP
Sbjct: 617 TCQDPD-----NAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYT 671
Query: 291 -CNCHNHTTECTYDPEIDEKRLSLDING---RYEGGGKCLNCQHNTEGINCNKCRPTYYR 346
C+++ EC +P + ING R G C N N C
Sbjct: 672 GSMCNSNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC------ 725
Query: 347 PYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGY-------FD 399
+G D L+ + C CDP +S NC+ + CE P C G F
Sbjct: 726 VHGACRDSLNGYK-CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFS 784
Query: 400 YPNCK----PCTCNLNGTEGEHCTPTDGL-CPCKYNYAGKSCEI---------CEDG--- 442
PNC+ C N +G G C C Y G +CE+ C +G
Sbjct: 785 GPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC 844
Query: 443 --YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN--------QCQAGYYNYP 492
E +C C T G+ C+ +C G +C CQAGY
Sbjct: 845 RQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY---- 900
Query: 493 TCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDP 552
+ + C D P+ C + C G CD CL G+ E C DP
Sbjct: 901 SGRNCETDIDDCRPNPCHNGGS---CTDGINTAFCD-CLPGFRGTFC--EEDINECASDP 954
Query: 553 --TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--- 607
G+ T C C C F G C+ PDC +C G TC D
Sbjct: 955 CRNGANCTDCVDSYTCTCPAGFSGIHCEN------NTPDCTESSC----FNGGTCVDGIN 1004
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNC-DPRGVTASFAGCGSVPAGELCQCKDR 666
+ C C F G+ C + + P C D RG+ C G CQ +
Sbjct: 1005 SFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHR--CTCPQGYTGPNCQ--NL 1060
Query: 667 VQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC-VCKQHVGERQC 725
V + CK Q + + CE C G C+ S C V Q G
Sbjct: 1061 VHWCDSSPCKNGGKCWQTHTQYRCE-CPSGWTGLY-----CDVPSVSCEVAAQRQGVDVA 1114
Query: 726 DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C G + + C C GS C+ +C G C
Sbjct: 1115 RLCQHGGLCVDAGNTHHC-RCQAGYTGSY---CEDLVDECSPSPCQNGATC 1161
Score = 83.8 bits (198), Expect = 1e-14
Identities = 142/576 (24%), Positives = 205/576 (35%), Gaps = 111/576 (19%)
Query: 253 VCRCQHNTCGPQCNK----CCSGFE--QKKWRISQNWDRFSCEPCN------CHNHTTEC 300
+C C GP C++ C G + + F C+ C EC
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC 456
Query: 301 TYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINC----NKCRPTYYRPYGKRWDELD 356
+P LD G ++ C+ C EG++C ++C + G+ D+++
Sbjct: 457 VSNP-CQNDATCLDQIGEFQ----CM-CMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
Query: 357 VCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGE 416
Q C+C F+ C+ + C P C D PN C C G G
Sbjct: 511 EFQ-CECPTGFTGHLCQYDVDECASTPCKNGAKC-------LDGPNTYTCVCT-EGYTGT 561
Query: 417 HCTPTDGLC---PCKYN-----YAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG 468
HC C PC Y A +C +C GY +CE N S C +L G
Sbjct: 562 HCEVDIDECDPDPCHYGSCKDGVATFTC-LCRPGYTG---HHCETNINECSSQPC-RLRG 616
Query: 469 DCTCKSKYSGRTCNQCQAGYYNYPTCKPC--NCDTSGTEPSIC-DDVSG-QCICKAGFGG 524
TC+ + C C G P C+ +C +S + C D + G +C C+ G+ G
Sbjct: 617 --TCQDPDNAYLCF-CLKGTTG-PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTG 672
Query: 525 PRC----DQCLSGYYMQVLGRERQCV---PCNCDPTGSTSTSCSAD-GKCN--------C 568
C D+C +G G + C C P G +C ++ +CN C
Sbjct: 673 SMCNSNIDEC-AGNPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECNSNPCVHGAC 730
Query: 569 LTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI--GSTCDDNGLCHCKSNFDGAKCDTCR 626
+ G +CD C PG+ NCD++ + + C + G C K G C TCR
Sbjct: 731 RDSLNGYKCD-CDPGWS------GTNCDINNNECESNPCVNGGTC--KDMTSGIVC-TCR 780
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
E F P C+ + C S P C D V G CN P E
Sbjct: 781 EGFSG-PNCQ----------TNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVV 829
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
C C G + + +S CVC + Q + D+ C
Sbjct: 830 LAPCAPSPCRNGGECRQ--SEDYESFSCVCPTAGAKGQTCEV----------DINECVLS 877
Query: 747 DCDIGGSIDNNCDKTTG--QCHCHSRVEGRRCDQPI 780
C G S C T G +CHC + GR C+ I
Sbjct: 878 PCRHGAS----CQNTHGXYRCHCQAGYSGRNCETDI 909
Score = 81.4 bits (192), Expect = 6e-14
Identities = 122/483 (25%), Positives = 168/483 (34%), Gaps = 75/483 (15%)
Query: 321 GGGKCLNCQHNTEGINCNK----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES 376
G +C+ C+ G NC + C P+ + G DV C C P F+ NCEE
Sbjct: 200 GSYRCV-CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA--GK 434
C P + +C G Y NC PC G++CT C N G
Sbjct: 259 DDC---PGNNCKNGGACVDGVNTY-NC-PCPPEWT---GQYCTEDVDECQLMPNACQNGG 310
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY----N 490
+C GY NC C G C + DC + + G TC+ A +Y +
Sbjct: 311 TCHNTHGGY------NCVC-VNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 491 YPTCKPCNCDTS-----GTEPSICD--DVSGQ--CICKAGFGGPRC----DQCL------ 531
T C+ + + E S CD V+G+ C C +G+ GP C D+C
Sbjct: 364 GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPC 423
Query: 532 --SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSP 582
+G + LG E QC+ C D S C D CL G QC C P
Sbjct: 424 EHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND--ATCLDQIGEFQC-MCMP 480
Query: 583 GYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
GY + + C + S C NG C K N +C T +EC P
Sbjct: 481 GY----EGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTP 536
Query: 643 RGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLN 702
+ A C P C C + G C ++ E +P C +C G
Sbjct: 537 ---CKNGAKCLDGPNTYTCVCTEGYTGTHCE------VDIDECDPDPCHYGSCK-DGVAT 586
Query: 703 SLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTT 762
C C+ ++ E C R D C C + G+ NC+
Sbjct: 587 FTCLCRPGYTGHHCETNINECSSQPCR---LRGTCQDPDNAYLCFC-LKGTTGPNCEINL 642
Query: 763 GQC 765
C
Sbjct: 643 DDC 645
Score = 77.4 bits (182), Expect = 9e-13
Identities = 137/563 (24%), Positives = 191/563 (33%), Gaps = 109/563 (19%)
Query: 227 IGGRCMCNG--HADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWD 284
+GG C H TC N LV C + C KC Q + W
Sbjct: 1033 LGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPC-KNGGKCWQTHTQYRCECPSGWT 1091
Query: 285 RFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTY 344
C+ + C E+ +R +D+ + GG C++ NT +C +C+ Y
Sbjct: 1092 GLYCDV-----PSVSC----EVAAQRQGVDVARLCQHGGLCVDAG-NTH--HC-RCQAGY 1138
Query: 345 YRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSS---------C 393
Y + D +D C P C + C + G C+C + +CS C
Sbjct: 1139 TGSYCE--DLVDECSPSPCQ---NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPC 1193
Query: 394 AYG--YFDYPNCKPCTCNLNGTEGEHCT--------PTDGL-----C----PCKYNYAGK 434
G D PN C+C GT+G HC P D + C C G
Sbjct: 1194 QNGGTCLDLPNTYKCSCP-RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGY 1252
Query: 435 SCEICEDGYYSPECKN----C---ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
SC C G+ C+ C C+ G+ + V C C++ ++GR C G
Sbjct: 1253 SCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVING 1311
Query: 488 YYNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLSGYYMQVLGRERQCV 546
CK C GT + G C C AGF G C+ R C
Sbjct: 1312 ------CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN-----------DARTCG 1354
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN-CDVSGSIGSTC 605
C G T S C CL F G +C + CL N C G+ T
Sbjct: 1355 SLRC-LNGGTCISGPRSPTCLCLGPFTGPECQ-----FPASSPCLGGNPCYNQGTCEPTS 1408
Query: 606 DDNGL-CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV--TASFAGCGSVPAGELC- 661
+ C C + F+G C Y++ + P + C ++C
Sbjct: 1409 ESPFYRCLCPAKFNGLLCHILD---YSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCS 1465
Query: 662 -QCKDRVQGRICNDCKPLY---W-----NLQEYNPFGCEQCN--CNLAGTLNSLGACNTK 710
QC + G DC + W +LQ + F C+ CN AG L C
Sbjct: 1466 LQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA 1525
Query: 711 SGQC------VCKQHVGERQCDQ 727
GQC CK H + CDQ
Sbjct: 1526 EGQCNPLYDQYCKDHFSDGHCDQ 1548
Score = 70.5 bits (165), Expect = 1e-10
Identities = 94/360 (26%), Positives = 130/360 (36%), Gaps = 58/360 (16%)
Query: 1735 ECQCPRAYRGLSCE----QCAEGHYRLPSGFCVP------CQC----NGHSDQCDVN--- 1777
+C C Y G+ CE +CA L +G C+ C+C GH Q DV+
Sbjct: 475 QCMCMPGYEGVHCEVNTDECASSPC-LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA 533
Query: 1778 TGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSE 1834
+ C N C D C C GY GT + I C P P + SC +
Sbjct: 534 STPCKNGAKCLDGPNTYTC-VCTEGY-----TGTHCEVDIDECD-PDPCHYG--SC--KD 582
Query: 1835 NGSLISCNCQPGYGGARCEY----CAAG---YYGIPEDTDLHTGDYCKPC----NCSGNI 1883
+ +C C+PGY G CE C++ G +D D +C NC N+
Sbjct: 583 GVATFTCLCRPGYTGHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINL 642
Query: 1884 NPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCD 1941
+ CDS G CL ++ G C C PG+ G S C C G +
Sbjct: 643 DDCASSPCDS--GTCLDKID---GYEC-ACEPGYTGSMCNSNIDECAGNPCHNGGTCEDG 696
Query: 1942 STTGTCVCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQ 1994
TC C G C + C + H L C+C T CD +N +
Sbjct: 697 INGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNE 756
Query: 1995 CRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD 2054
C V G C +G ++G NC T + + C+ V G KC+
Sbjct: 757 CESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYKCN 816
Score = 68.9 bits (161), Expect = 3e-10
Identities = 117/475 (24%), Positives = 167/475 (35%), Gaps = 83/475 (17%)
Query: 254 CRCQHNTCGPQC----NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
CRCQ G C ++C Q + +SC+ C H C+ EIDE
Sbjct: 1132 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCK-CVAGYHGVNCS--EEIDEC 1188
Query: 310 RLSLDINGRYEGGGKCLN--------CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC 361
++ + GG CL+ C T+G++C P D + C
Sbjct: 1189 -----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV----DPVSRSPKC 1239
Query: 362 QCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
F+ G C ++ G C C P F C D C C+ GT+
Sbjct: 1240 -----FNNGTCVDQVGGYSCTCPPGFVGERCEG------DVNECLSNPCDARGTQNCVQR 1288
Query: 420 PTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTG-DCTCKSKYSG 478
D C C+ + G+ CE +G CK C G+ + + G C C + + G
Sbjct: 1289 VNDFHCECRAGHTGRRCESVING-----CKGKPCKNGGTCAVASNTARGFICKCPAGFEG 1343
Query: 479 RTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQV 538
TC + TC C GT I S C+C F GP C S
Sbjct: 1344 ATCEN------DARTCGSLRCLNGGT--CISGPRSPTCLCLGPFTGPECQFPASS---PC 1392
Query: 539 LGRERQCVPCNCDPTG-STSTSCSADGKCNCLT------NF-GGAQCDQCSPGYYKYPDC 590
LG C+PT S C K N L +F GGA D P + +
Sbjct: 1393 LGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACEL 1452
Query: 591 LSCNCDVSGSIGSTCDDNGLC-----HCKSNFDGAKCDTCREQFYNYPACEECNCDPRGV 645
C D + S +N C C NF+ C + + + +CD +
Sbjct: 1453 PECQEDAGNKVCSLQCNNHACGWDGGDCSLNFND-PWKNCTQSLQCWKYFSDGHCDSQ-- 1509
Query: 646 TASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY--WNLQEYNPFGCEQCNCNLA 698
+ AGC + G CQ R +G+ C PLY + ++ C+Q CN A
Sbjct: 1510 -CNSAGC--LFDGFDCQ---RAEGQ----CNPLYDQYCKDHFSDGHCDQ-GCNSA 1553
Score = 64.9 bits (151), Expect = 5e-09
Identities = 85/330 (25%), Positives = 118/330 (35%), Gaps = 56/330 (16%)
Query: 1767 CNGHSDQCDVNTGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS 1823
CN + D+C N C N C D G C C GYH + +C C
Sbjct: 675 CNSNIDECAGNP--CHNGGTCEDGINGFTCR-CPEGYHDPTCLSEVNECNSNPCVHG--- 728
Query: 1824 NNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIP-----EDTDLHTGDYCKPC- 1877
+C S NG C+C PG+ G C+ P D+ +G C C
Sbjct: 729 -----ACRDSLNG--YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCT-CR 780
Query: 1878 ------NCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAP--GFYGDAIFSKNCTA 1929
NC NIN C +N C+++ AG CN P G + + + C
Sbjct: 781 EGFSGPNCQTNINECASNPC--LNKGT--CIDDVAGYKCNCLLPYTGATCEVVLAP-CAP 835
Query: 1930 CICDEFGMA--DCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQ 1987
C G D + +CVC G K C D +N + +PC G + ++T
Sbjct: 836 SPCRNGGECRQSEDYESFSCVCPTA--GAKGQTCEVD---INECV-LSPCRHGASCQNTH 889
Query: 1988 CDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPG 2047
+C C G +G+ C+ D C C+ G S N T C+CLPG
Sbjct: 890 ---GXYRCHCQAGYSGRNCETDI--------DDCRPNPCHNGGSCTDGIN-TAFCDCLPG 937
Query: 2048 VIGEKCDRCPERWVLIPQEGCLECDSCTDA 2077
G C+ P C C D+
Sbjct: 938 FRGTFCEEDINECASDPCRNGANCTDCVDS 967
Score = 64.5 bits (150), Expect = 7e-09
Identities = 100/375 (26%), Positives = 127/375 (33%), Gaps = 44/375 (11%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC+ G +C+ G GF P C + ++C N CLN C D+ G
Sbjct: 756 ECESNPCVNGGTCKDMTSGIVCTCREGFSGP-NCQTNINECASNP--CLNKGTCIDDVAG 812
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP-GYGG 1849
C C+ Y G AT + ++ C P P N C SE+ SC C G G
Sbjct: 813 YKCN-CLLPYTG-ATC----EVVLAPCA-PSPCRNGG-ECRQSEDYESFSCVCPTAGAKG 864
Query: 1850 ARCEY----CAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDC 1898
CE C G Y C NC +I+ P C + G C
Sbjct: 865 QTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHN-GGSC 923
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF-GMADCDSTTG--TCVCRPGVIG 1955
+N A C+ C PGF G ++ C D A+C TC C G G
Sbjct: 924 TDGINT---AFCD-CLPGFRG-TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSG 978
Query: 1956 EKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWN 2015
C+ PD + G T C GI S + C C V C G
Sbjct: 979 IHCENNTPDCTESSCFNGGT-CVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTC 1037
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
G C C GY+ N C+ P G KC W Q C EC S
Sbjct: 1038 QDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC------WQTHTQYRC-ECPSGW 1090
Query: 2076 DALIFSVEDLSALLA 2090
L V +S +A
Sbjct: 1091 TGLYCDVPSVSCEVA 1105
Score = 63.7 bits (148), Expect = 1e-08
Identities = 114/460 (24%), Positives = 155/460 (33%), Gaps = 75/460 (16%)
Query: 360 PCQCDPHFSTGNCEEESGR------CECRPEFQPPDCSSCAYGYFDYPNCKPCTCN--LN 411
PC P + G C R C C F P C + P C N N
Sbjct: 62 PCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT--------PLDNACLTNPCRN 113
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + T T+ C C ++GKSC+ + +P +C SY+C
Sbjct: 114 GGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPF-EASYICH------- 165
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCDQ 529
C + G TC Q N KP C GT C + G +C+C+A GP C++
Sbjct: 166 CPPSFHGPTCRQ----DVNECGQKPRLCRHGGT----CHNEVGSYRCVCRATHTGPNCER 217
Query: 530 ---------CLSGYYMQVLG---RERQCVP----CNCDPT--GSTSTSCSADGKCNCLTN 571
C +G + G E C+P NC+ +C G C N
Sbjct: 218 PYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN 277
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCDD--NGL-CHCKSNFDGAKCDTCRE 627
C G Y D C + G TC + G C C + + G C +
Sbjct: 278 TYNCPCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENID 337
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICN-----DCKPLYWNL 682
+ C R V + + C G LC D CN D P+
Sbjct: 338 DCASAACFHGATCHDR-VASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGA--CNTKSGQCVCKQHVGERQCDQCLDGFYRLQTN-D 739
P G C+ SLGA C +G+C+ +G +C QCL G+ + D
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCE-HAGKCI--NTLGSFEC-QCLQGYTGPRCEID 452
Query: 740 VFGCTECDCDIGGSIDNNCDKTTG--QCHCHSRVEGRRCD 777
V C C D C G QC C EG C+
Sbjct: 453 VNECVSNPC----QNDATCLDQIGEFQCMCMPGYEGVHCE 488
Score = 62.1 bits (144), Expect = 4e-08
Identities = 92/376 (24%), Positives = 132/376 (35%), Gaps = 57/376 (15%)
Query: 1731 TSVEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTI 1789
++++EC + G +CE G R P G+ P C ++C+ N + C D+
Sbjct: 677 SNIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPT-CLSEVNECNSNPCVHGACRDSLN 735
Query: 1790 GDHCEFCMSGYHGD--------------ATVGTPRDC---LICACPMPYPSNNFALSC-D 1831
G C+ C G+ G GT +D ++C C + N + +
Sbjct: 736 GYKCD-CDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINE 794
Query: 1832 LSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC 1891
+ N L C G +C C Y G + L C P C ++ G C
Sbjct: 795 CASNPCLNKGTCIDDVAGYKCN-CLLPYTGATCEVVLAP---CAPSPC------RNGGEC 844
Query: 1892 -DSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGT--CV 1948
S + + CV TAGA C + C C G A C +T G C
Sbjct: 845 RQSEDYESFSCVCPTAGAKGQTCE-------VDINECVLSPC-RHG-ASCQNTHGXYRCH 895
Query: 1949 CRPGVIGEKC----DRCAPD--HWG--LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C+ G G C D C P+ H G G+ C+C T C++D +C
Sbjct: 896 CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPC 955
Query: 2001 VTGKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
G C C + G HC NT C G C+ G+ C CP
Sbjct: 956 RNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG--TCVDGINSFTC-LCPP 1012
Query: 2059 RWV-LIPQEGCLECDS 2073
+ Q ECDS
Sbjct: 1013 GFTGSYCQHVVNECDS 1028
Score = 57.2 bits (132), Expect = 1e-06
Identities = 91/361 (25%), Positives = 130/361 (36%), Gaps = 77/361 (21%)
Query: 1735 ECQCPRAYRGLSCEQ--------CAEGHYRLPSGFCVPCQC--NGHSDQC--DVN----- 1777
+C+CP + G SC+Q CA G LP C C + H C DVN
Sbjct: 126 KCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK 185
Query: 1778 TGICLN--CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
+C + N +G + C + + G R + C+ P P N +C
Sbjct: 186 PRLCRHGGTCHNEVGSYRCVCRATHTGP---NCERPYVPCS---PSPCQNGG-TC--RPT 236
Query: 1836 GSLI-SCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPC--NCSGNINPQDP 1888
G + C C PG+ G CE C Y PC +G +D
Sbjct: 237 GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWTGQYCTEDV 296
Query: 1889 GSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDST 1943
C + C C N G C +C G+ G+ +C + C F A C
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNC-VCVNGWTGEDCSENIDDCASAAC--FHGATCHDR 353
Query: 1944 TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRC 1997
+ C C G G C LN PCN E + CD + NG+ C C
Sbjct: 354 VASFYCECPHGRTGLLCH--------LNDACISNPCN-----EGSNCDTNPVNGKAICTC 400
Query: 1998 AKGVTGKQC----DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G TG C D+C+ G + C+H G + + + +C+CL G G +C
Sbjct: 401 PSGYTGPACSQDVDECSLG-----ANPCEH----AGKCINTL--GSFECQCLQGYTGPRC 449
Query: 2054 D 2054
+
Sbjct: 450 E 450
Score = 57.2 bits (132), Expect = 1e-06
Identities = 83/339 (24%), Positives = 117/339 (34%), Gaps = 51/339 (15%)
Query: 1733 VEECQCPRAYRGLSCEQCAEGHYRLP---SGFC------VPCQC-NGHSD-QCDVNTGIC 1781
+ C CP+ Y G +C+ P G C C+C +G + CDV + C
Sbjct: 1043 LHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC 1102
Query: 1782 LNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFA-LSCDLSENGSLIS 1840
A D C HG V + C C Y + L + S +
Sbjct: 1103 EVAAQRQGVDVARLCQ---HGGLCVDAG-NTHHCRCQAGYTGSYCEDLVDECSPSPCQNG 1158
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC-DSINGDCL 1899
C GG C+ C AGY+G+ ++ D C C Q+ G+C D N
Sbjct: 1159 ATCTDYLGGYSCK-CVAGYHGVNCSEEI---DECLSHPC------QNGGTCLDLPNTYKC 1208
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTG--TCVCRPGVIGEK 1957
C T G C + C F C G +C C PG +GE+
Sbjct: 1209 SCPRGTQGVHCEINVDDCNPPVDPVSRSPKC----FNNGTCVDQVGGYSCTCPPGFVGER 1264
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
C+ +N L PC+ Q +D C C G TG++C+
Sbjct: 1265 CE------GDVNECLS-NPCDARGTQNCVQRVND-FHCECRAGHTGRRCESVI------- 1309
Query: 2018 KDGCDHCNCNTGYSVGFMCN-ATG-QCECLPGVIGEKCD 2054
+GC C G + N A G C+C G G C+
Sbjct: 1310 -NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1347
Score = 54.8 bits (126), Expect = 6e-06
Identities = 77/304 (25%), Positives = 105/304 (34%), Gaps = 56/304 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHS-DQCDVNTGICLNCADNTIGDHC 1793
C+CP + GL C+ +PS C V Q G + + G+C++ A NT HC
Sbjct: 1084 CECPSGWTGLYCD--------VPSVSCEVAAQRQGVDVARLCQHGGLCVD-AGNT--HHC 1132
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C +GY G +C P P N A D SC C GY G C
Sbjct: 1133 R-CQAGYTGSYCEDLVDEC------SPSPCQNGATCTDYLGG---YSCKCVAGYHGVNCS 1182
Query: 1854 Y---------CAAG--YYGIPEDTDLHTGDYCKPCNCSGNIN----PQDPGSCDSINGDC 1898
C G +P + +C N++ P DP S +
Sbjct: 1183 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1242
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGT--CVCRPGVI 1954
CV+ G +C C PGF G+ C + CD G +C C CR G
Sbjct: 1243 GTCVDQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 1301
Query: 1955 GEKCDRCAPDHWGL------------NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G +C+ G NT G C C E C++D C + +
Sbjct: 1302 GRRCESVINGCKGKPCKNGGTCAVASNTARGFI-CKCPAGFEGATCENDARTCGSLRCLN 1360
Query: 2003 GKQC 2006
G C
Sbjct: 1361 GGTC 1364
Score = 54.0 bits (124), Expect = 1e-05
Identities = 69/249 (27%), Positives = 89/249 (35%), Gaps = 41/249 (16%)
Query: 1315 SPNETGLCREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACR 1374
+P G CR+++ + + G CD + + E E N CK G C+ CR
Sbjct: 723 NPCVHGACRDSLNGYKCDCDPGWSGTNCD-INNNECESNPCVNGGTCKDMTSGIVCT-CR 780
Query: 1375 TGYYGFPNCR---------PCHCPSTAICDDNGM-CICPKNVEGENCD----RCKPYTF- 1419
G+ G PNC+ PC T I D G C C G C+ C P
Sbjct: 781 EGFSG-PNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 1420 NFDVQRGCDD-----CNCNPLGVVGNQLQCEADSGKCA---CR-----ENVRGRVCDHCV 1466
N R +D C C G G CE D +C CR +N G HC
Sbjct: 840 NGGECRQSEDYESFSCVCPTAGAKGQT--CEVDINECVLSPCRHGASCQNTHGXYRCHCQ 897
Query: 1467 PGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQD 1520
G+ DC C+ G+ D NTA C C RG C+ E +
Sbjct: 898 AGYSGRNCETDIDDCRPNPCHNGGSCTDGI--NTAFCDCLPGFRGTFCEEDINECASDPC 955
Query: 1521 DNPDGCTKC 1529
N CT C
Sbjct: 956 RNGANCTDC 964
Score = 51.6 bits (118), Expect = 5e-05
Identities = 86/351 (24%), Positives = 117/351 (33%), Gaps = 65/351 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
+C CPR +G+ CE + C P S +C N G C++ +G +
Sbjct: 1207 KCSCPRGTQGVHCEINVDD--------CNPPVDPVSRSPKC-FNNGTCVD----QVGGYS 1253
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE 1853
C G+ G+ G +CL C N C N C C+ G+ G RCE
Sbjct: 1254 CTCPPGFVGERCEGDVNECLSNPCDARGTQN-----CVQRVND--FHCECRAGHTGRRCE 1306
Query: 1854 YCAAGYYGIP--------EDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCLK---C 1901
G G P ++ G CK P G D +C S+ CL C
Sbjct: 1307 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR--CLNGGTC 1364
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKNCTACICDE--FGMADCDSTTGT----CVCRPGVIG 1955
++ C LC F G + C+ + C+ T+ + C+C G
Sbjct: 1365 ISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 1423
Query: 1956 EKCDRCAPDHWGLNTGLGCTP-----------CN-------CGIASESTQCDDDNGQCRC 1997
C +G G P C C + + C D G C
Sbjct: 1424 LLC-HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSL 1482
Query: 1998 AKGVTGKQCDQCAAGFWNYTKDG-CD-HCNCNTGYSVGFMC-NATGQCECL 2045
K C Q + W Y DG CD CN GF C A GQC L
Sbjct: 1483 NFNDPWKNCTQ-SLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPL 1532
Score = 50.0 bits (114), Expect = 2e-04
Identities = 86/350 (24%), Positives = 122/350 (34%), Gaps = 51/350 (14%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVPCQCNGHSDQCDVN-TGICLNCADNTIG 1790
EC C + G +CE+ + G+ G CV N ++ C TG C ++
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGACVD-GVNTYNCPCPPEWTG--QYCTEDV-- 296
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
D C+ + T C C + D SEN + C + GA
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGE------DCSEN--IDDCASAACFHGA 348
Query: 1851 RCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGS-CDSINGDCLKCVNNTAGAA 1909
C A +Y E TG C N + NP + GS CD+ N G A
Sbjct: 349 TCHDRVASFYC--ECPHGRTGLLCH-LNDACISNPCNEGSNCDT---------NPVNGKA 396
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN 1969
C G+ G A S++ C G C+ G C+ G +C +C + G
Sbjct: 397 ICTCPSGYTGPAC-SQDVDEC---SLGANPCEHA-GKCINTLGSF--EC-QCLQGYTGPR 448
Query: 1970 TGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQC----DQCAAGFWNYTKDGCD- 2022
+ C C D G QC C G G C D+CA+ + D
Sbjct: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
Query: 2023 ----HCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPERWVLIPQEG 2067
C C TG++ G +C +C P G KC P + + EG
Sbjct: 509 INEFQCECPTGFT-GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEG 557
Score = 45.6 bits (103), Expect = 0.003
Identities = 66/240 (27%), Positives = 87/240 (36%), Gaps = 47/240 (19%)
Query: 1877 CNCSGN-INP--QDPGSCDSI---NGDCLKCVNN--TAGAACNLCAPGFYGDAIFSKNCT 1928
C C G + P QDP C S N V+ A AC+ CA GF G +
Sbjct: 46 CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACS-CALGFSGPLCLTPLDN 104
Query: 1929 ACI---CDEFGMADCDSTTG-TCVCRPGVIGEKC---DRCAPDHWGLNTGLGCTP----- 1976
AC+ C G D + T C C PG G+ C D CA + G C P
Sbjct: 105 ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA--NGGQCLPFEASY 162
Query: 1977 -CNCGIASESTQCDDDNGQCR-----CAKGVT-----GKQCDQCAAGFWNYTKDGCDH-- 2023
C+C + C D +C C G T G C A +T C+
Sbjct: 163 ICHCPPSFHGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRA---THTGPNCERPY 219
Query: 2024 --CN---CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTDAL 2078
C+ C G + + T +C CLPG G+ C+ E P C +C D +
Sbjct: 220 VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE---ENIDDCPGNNCKNGGACVDGV 276
Score = 45.2 bits (102), Expect = 0.005
Identities = 50/197 (25%), Positives = 67/197 (34%), Gaps = 28/197 (14%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-----CDDNGMCICPKNVEGEN 1410
GG C PN +C G + N C+ P + C +NG C+ V G +
Sbjct: 1196 GGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV--DQVGGYS 1253
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQC--EADSGKCACRENVRGRVCDHCVPG 1468
C C P + ++C NP G Q C + C CR GR C+ + G
Sbjct: 1254 CT-CPPGFVGERCEGDVNECLSNPCDARGTQ-NCVQRVNDFHCECRAGHTGRRCESVING 1311
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQ---CYCKTNVRGQACDTCKEEYFNLQDDNPDG 1525
C C GT NTA+ C C G C+ +L+ N
Sbjct: 1312 ------CKGKPCKNGGTC--AVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1363
Query: 1526 CTK------CFCFGKTT 1536
C C C G T
Sbjct: 1364 CISGPRSPTCLCLGPFT 1380
Score = 43.6 bits (98), Expect = 0.014
Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 27/187 (14%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRP--CHCP 1389
C C G T C +C P G TC+ C GY+G NC C
Sbjct: 1132 CRCQ-AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGV-NCSEEIDECL 1189
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
S C + G C+ N +C R T + DDCN P+ V +C ++G
Sbjct: 1190 SHP-CQNGGTCLDLPNTYKCSCPRG---TQGVHCEINVDDCN-PPVDPVSRSPKC-FNNG 1243
Query: 1450 KCACRENVRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
C + V G C C PG +C C+ GT V N C C+
Sbjct: 1244 TCV--DQVGGYSCT-CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1300
Query: 1504 RGQACDT 1510
G+ C++
Sbjct: 1301 TGRRCES 1307
Score = 43.2 bits (97), Expect = 0.018
Identities = 51/183 (27%), Positives = 64/183 (34%), Gaps = 35/183 (19%)
Query: 1361 CKPNVIGRTCSACRTGYYG------FPNC--RPCHCPSTAICDDNG-MCICPKNVEGENC 1411
CK V TC CR GY G C +PC T DN +C C K G NC
Sbjct: 580 CKDGVATFTC-LCRPGYTGHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNC 638
Query: 1412 DRCKPYTFNFDVQRG-CDD------CNCNPLGVVGNQLQCEADSGKCA---------CRE 1455
+ + G C D C C P G G+ C ++ +CA C +
Sbjct: 639 EINLDDCASSPCDSGTCLDKIDGYECACEP-GYTGS--MCNSNIDECAGNPCHNGGTCED 695
Query: 1456 NVRGRVCDHCVPGHYAFPDCYQ--CTCNRHGTTYDVC--DQNTAQCYCKTNVRGQACDTC 1511
+ G C C P Y P C CN + + C N +C C G CD
Sbjct: 696 GINGFTC-RC-PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN 753
Query: 1512 KEE 1514
E
Sbjct: 754 NNE 756
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/265 (22%), Positives = 87/265 (32%), Gaps = 55/265 (20%)
Query: 516 CICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGA 575
C C GF GP C L + C+ C G+ + KC C + G
Sbjct: 87 CSCALGFSGPLCLTPL----------DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 576 QCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC 635
C Q P C S C +G + + +CHC +F G TCR+
Sbjct: 137 SCQQADP-------CASNPC-ANGGQCLPFEASYICHCPPSFHG---PTCRQD------V 179
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNC 695
EC PR + C + C C+ G C + Y P C C
Sbjct: 180 NECGQKPR-LCRHGGTCHNEVGSYRCVCRATHTGPNCE---------RPYVP--CSPSPC 227
Query: 696 NLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSID 755
GT G + +C C + C++ +D C +C GG+
Sbjct: 228 QNGGTCRPTG---DVTHECACLPGFTGQNCEENID-----------DCPGNNCKNGGACV 273
Query: 756 NNCDKTTGQCHCHSRVEGRRCDQPI 780
+ + T C C G+ C + +
Sbjct: 274 DGVN--TYNCPCPPEWTGQYCTEDV 296
Score = 42.7 bits (96), Expect = 0.024
Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 27/152 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGENC- 1411
G +C C+P G C++ G PCH T C+D NG C CP+ C
Sbjct: 661 GYECACEPGYTGSMCNSNIDECAG----NPCHNGGT--CEDGINGFTCRCPEGYHDPTCL 714
Query: 1412 DRCKPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
N V C D C+C+P G G C+ ++ +C V G C
Sbjct: 715 SEVNECNSNPCVHGACRDSLNGYKCDCDP-GWSGT--NCDINNNECESNPCVNGGTCKDM 771
Query: 1466 VPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
G CTC R G + C N +C
Sbjct: 772 TSG-------IVCTC-REGFSGPNCQTNINEC 795
Score = 39.1 bits (87), Expect = 0.30
Identities = 64/257 (24%), Positives = 87/257 (33%), Gaps = 33/257 (12%)
Query: 1299 YTREFIEQCASYNYYISPNETGL-CREAMFSITSEYNSGARPCLCDFMGSTELECNTF-G 1356
+ E I +CAS P G C + + S T +G C+ E + F G
Sbjct: 942 FCEEDINECAS-----DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG 996
Query: 1357 GQCPCKPNVIGRTCSACRTGYYG---FPNC--RPCHCPSTAICDDNGM--CICPKNVEGE 1409
G C N C TG Y C RPC T D G+ C CP+ G
Sbjct: 997 GTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQ-DGRGLHRCTCPQGYTGP 1055
Query: 1410 NCDRCKPYTFNFDVQRGCDDCNCNPLGV---VGNQLQCEADSGKCACRENVRGRVCDHCV 1466
NC ++ CD C G Q +CE SG +V C+ V
Sbjct: 1056 NCQ---------NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE--V 1104
Query: 1467 PGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
D + C G D NT C C+ G C+ +E N C
Sbjct: 1105 AAQRQGVDVARL-CQHGGLCVDA--GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 1161
Query: 1527 TKCFCFGKTTRCSSSYY 1543
T + G + +C + Y+
Sbjct: 1162 TD-YLGGYSCKCVAGYH 1177
Score = 34.3 bits (75), Expect = 8.4
Identities = 51/192 (26%), Positives = 62/192 (32%), Gaps = 28/192 (14%)
Query: 1338 RPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDN 1397
RP C GS NT C C P G C P +C C D+
Sbjct: 913 RPNPCHNGGSCTDGINT--AFCDCLPGFRGTFCEEDINECASDPCRNGANCTD---CVDS 967
Query: 1398 GMCICPKNVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQ---CEA 1446
C CP G +C+ P G C D C C P G G+ Q E
Sbjct: 968 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPP-GFTGSYCQHVVNEC 1026
Query: 1447 DSGKCACRENVR-GRVCDHCV-PGHYAFPDC----YQC---TCNRHGTTYDVCDQNTAQC 1497
DS C + GR C P Y P+C + C C G + Q +C
Sbjct: 1027 DSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ--YRC 1084
Query: 1498 YCKTNVRGQACD 1509
C + G CD
Sbjct: 1085 ECPSGWTGLYCD 1096
>AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.
Length = 2923
Score = 90.2 bits (214), Expect = 1e-16
Identities = 69/254 (27%), Positives = 101/254 (39%), Gaps = 32/254 (12%)
Query: 427 CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD----CTCKSKYSGRTC 481
C ++ SC C+ GYY C N C+ N S K + C C Y G C
Sbjct: 1808 CSNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYC 1866
Query: 482 NQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
C G++ +PTC PCNCD S G +P C+ SG+C CK P
Sbjct: 1867 ETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD-CNKTSGECHCKENHYRPPGSPT----- 1920
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
C+ C+C PTGS S C DG+C C G QCD+C + + +
Sbjct: 1921 ---------CLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCD---NPFAEVTTNG 1968
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C+V+ + G+ ++ F C + + A C+ + + C S
Sbjct: 1969 CEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFG-TAVRHCDEHRGWLPPNLFNCTS 2027
Query: 655 VPAGELCQCKDRVQ 668
+ EL +R+Q
Sbjct: 2028 ITFSELKGFAERLQ 2041
Score = 86.2 bits (204), Expect = 2e-15
Identities = 48/162 (29%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C ++ + +C+ C P YY G + PC+ + CEC P +
Sbjct: 1808 CSNDWDSYSCS-CDPGYY---GDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG 1863
Query: 388 PDCSS-----CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P C + C G++ +P C PC C+++ C T G C CK N+
Sbjct: 1864 PYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPG------ 1917
Query: 443 YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
SP C C+C GS+S VCD G C CK GR C++C
Sbjct: 1918 --SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 80.2 bits (189), Expect = 1e-13
Identities = 57/190 (30%), Positives = 80/190 (42%), Gaps = 27/190 (14%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG 412
+ ++V Q C + C S C ++ CS C GY+ NC C+LN
Sbjct: 1783 ESINVEQGCSLPDPCDSNPCPANS---YCSNDWDSYSCS-CDPGYYG-DNCTN-VCDLNP 1836
Query: 413 TEGEH-CT-----PTDGLCPCKYNYAGKSCEI-----CEDGYYS-PECKNCECNTVGSVS 460
E + CT P C C NY G CE C G++ P C C C+
Sbjct: 1837 CEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFD 1896
Query: 461 YVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
C+K +G+C CK + + PTC C+C +G+ +CD GQC CK
Sbjct: 1897 PDCNKTSGECHCKENHYRPPGS---------PTCLLCDCYPTGSLSRVCDPEDGQCPCKP 1947
Query: 521 GFGGPRCDQC 530
G G +CD+C
Sbjct: 1948 GVIGRQCDRC 1957
Score = 71.7 bits (168), Expect = 5e-11
Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 15/177 (8%)
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDE-KRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
S +WD +SC C+ + CT +++ + S+ G C N G
Sbjct: 1809 SNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG---P 1864
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAYGY 397
C +P + W C PC CD +C + SG C C+ P S
Sbjct: 1865 YCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGS------ 1918
Query: 398 FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
P C C C G+ C P DG CPCK G+ C+ C++ + CE N
Sbjct: 1919 ---PTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVN 1972
Score = 70.1 bits (164), Expect = 1e-10
Identities = 73/276 (26%), Positives = 99/276 (35%), Gaps = 52/276 (18%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
C+ P P SN + S + SC+C PGY G C DL+ ++
Sbjct: 1791 CSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNVC----------DLNPCEHQ 1840
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-----CAPGFYGDAIFSKNCTA 1929
C P P +G +C N G C C G++G C
Sbjct: 1841 SVCTRK----PSAP------HGYTCECPPNYLGPYCETRIDQPCPRGWWGHP----TCGP 1886
Query: 1930 CICD-EFGM-ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASEST 1986
C CD G DC+ T+G C C+ +H+ C C+C S S
Sbjct: 1887 CNCDVSKGFDPDCNKTSGECHCKE------------NHYRPPGSPTCLLCDCYPTGSLSR 1934
Query: 1987 QCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT----- 2039
CD ++GQC C GV G+QCD+C F T +GC+ + +C G T
Sbjct: 1935 VCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLP 1994
Query: 2040 GQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C G G C E +P C S T
Sbjct: 1995 AAAPCPKGSFGTAVRHCDEHRGWLP-PNLFNCTSIT 2029
Score = 67.7 bits (158), Expect = 7e-10
Identities = 53/195 (27%), Positives = 78/195 (40%), Gaps = 30/195 (15%)
Query: 592 SCNCDVSGSIGSTCDDNGL---CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTAS 648
S N + S+ CD N +C +++D C +C +Y C+ +P +
Sbjct: 1784 SINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSC-SCDPGYYGDNCTNVCDLNPCEHQSV 1842
Query: 649 FAGCGSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S P G C+C G C C +W +P C CNC+++ +
Sbjct: 1843 CTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWG----HPT-CGPCNCDVSKGFDP 1897
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
CN SG+C CK++ YR + C CDC GS+ CD G
Sbjct: 1898 --DCNKTSGECHCKEN------------HYRPPGSPT--CLLCDCYPTGSLSRVCDPEDG 1941
Query: 764 QCHCHSRVEGRRCDQ 778
QC C V GR+CD+
Sbjct: 1942 QCPCKPGVIGRQCDR 1956
Score = 67.3 bits (157), Expect = 1e-09
Identities = 60/199 (30%), Positives = 89/199 (44%), Gaps = 37/199 (18%)
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCD---- 606
P S C A+ C+ ++ C C PGYY +C + CD++ S C
Sbjct: 1794 PDPCDSNPCPANSYCS--NDWDSYSCS-CDPGYYG-DNCTNV-CDLNPCEHQSVCTRKPS 1848
Query: 607 -DNGL-CHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
+G C C N+ G C+T C ++ +P C CNCD V+ F + +GE
Sbjct: 1849 APHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCD---VSKGFDPDCNKTSGE 1905
Query: 660 LCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
C CK+ N +P +P C C+C G+L+ + C+ + GQC CK
Sbjct: 1906 -CHCKE-------NHYRP------PGSPT-CLLCDCYPTGSLSRV--CDPEDGQCPCKPG 1948
Query: 720 VGERQCDQCLDGFYRLQTN 738
V RQCD+C + F + TN
Sbjct: 1949 VIGRQCDRCDNPFAEVTTN 1967
Score = 66.1 bits (154), Expect = 2e-09
Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 25/159 (15%)
Query: 1369 TCSACRTGYYGFPNC------RPCH----CPSTAICDDNGMCICPKNVEGENCDRC--KP 1416
+CS C GYYG NC PC C C CP N G C+ +P
Sbjct: 1816 SCS-CDPGYYG-DNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQP 1873
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C CNC+ G C SG+C C+EN + PG P C
Sbjct: 1874 CPRGWWGHPTCGPCNCDVSK--GFDPDCNKTSGECHCKEN------HYRPPGS---PTCL 1922
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C G+ VCD QC CK V G+ CD C +
Sbjct: 1923 LCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPF 1961
Score = 64.1 bits (149), Expect = 9e-09
Identities = 38/115 (33%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 1356 GGQCPCKPNVIGRTCSA-----CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGEN 1410
G C C PN +G C C G++G P C PC+C + D + C K GE
Sbjct: 1852 GYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD----CNK-TSGE- 1905
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
C CK + C C+C P G + C+ + G+C C+ V GR CD C
Sbjct: 1906 C-HCKENHYRPPGSPTCLLCDCYPTGSLSR--VCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 62.9 bits (146), Expect = 2e-08
Identities = 54/170 (31%), Positives = 69/170 (40%), Gaps = 44/170 (25%)
Query: 1811 DCLICACPMPYPSNNFALSCDLS--ENGSL----------ISCNCQPGYGGARCEY---- 1854
D C+C Y +N CDL+ E+ S+ +C C P Y G CE
Sbjct: 1813 DSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQ 1872
Query: 1855 -CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
C G++G P C PCNC + DP C+ +G+C C N +
Sbjct: 1873 PCPRGWWGHPT---------CGPCNCDVS-KGFDP-DCNKTSGEC-HCKEN------HYR 1914
Query: 1914 APGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRC 1961
PG S C C C G CD G C C+PGVIG +CDRC
Sbjct: 1915 PPG-------SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 51.6 bits (118), Expect = 5e-05
Identities = 40/125 (32%), Positives = 56/125 (44%), Gaps = 27/125 (21%)
Query: 1736 CQCPRAYRGLSCEQ-----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
C+CP Y G CE C G + P+ C PC C DV+ G +C N
Sbjct: 1855 CECPPNYLGPYCETRIDQPCPRGWWGHPT--CGPCNC-------DVSKGFDPDC--NKTS 1903
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C ++ G+P CL+C C YP+ + + CD E+G C C+PG G
Sbjct: 1904 GECH-CKENHYRPP--GSPT-CLLCDC---YPTGSLSRVCD-PEDGQ---CPCKPGVIGR 1952
Query: 1851 RCEYC 1855
+C+ C
Sbjct: 1953 QCDRC 1957
Score = 50.0 bits (114), Expect = 2e-04
Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA----IC 1394
PC CD + +CN G+C CK N G P C C C T +C
Sbjct: 1886 PCNCDVSKGFDPDCNKTSGECHCKENHYRPP---------GSPTCLLCDCYPTGSLSRVC 1936
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D ++G C C V G CDRC
Sbjct: 1937 DPEDGQCPCKPGVIGRQCDRC 1957
Score = 34.7 bits (76), Expect = 6.4
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTG--TCVCRPGVIGEK 1957
++ G C C PGF GD ++ C + C G C S G TC+CR G GE
Sbjct: 1266 IHPVGGLRCR-CPPGFTGDYCETEVDLCYSRPCGPHGR--CRSREGGYTCLCRDGYTGEH 1322
Query: 1958 CD 1959
C+
Sbjct: 1323 CE 1324
Score = 34.3 bits (75), Expect = 8.4
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHC-- 418
C+C P F+ CE E C RP C S GY C C +G GEHC
Sbjct: 1274 CRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGY-------TCLCR-DGYTGEHCEV 1325
Query: 419 TPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
+ G C G +C G + +C
Sbjct: 1326 SARSGRCTPGVCKNGGTCVNLLVGGFKCDC 1355
>AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane helix
receptor protein.
Length = 2923
Score = 90.2 bits (214), Expect = 1e-16
Identities = 69/254 (27%), Positives = 101/254 (39%), Gaps = 32/254 (12%)
Query: 427 CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD----CTCKSKYSGRTC 481
C ++ SC C+ GYY C N C+ N S K + C C Y G C
Sbjct: 1808 CSNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYC 1866
Query: 482 NQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
C G++ +PTC PCNCD S G +P C+ SG+C CK P
Sbjct: 1867 ETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD-CNKTSGECHCKENHYRPPGSPT----- 1920
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
C+ C+C PTGS S C DG+C C G QCD+C + + +
Sbjct: 1921 ---------CLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCD---NPFAEVTTNG 1968
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C+V+ + G+ ++ F C + + A C+ + + C S
Sbjct: 1969 CEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFG-TAVRHCDEHRGWLPPNLFNCTS 2027
Query: 655 VPAGELCQCKDRVQ 668
+ EL +R+Q
Sbjct: 2028 ITFSELKGFAERLQ 2041
Score = 86.2 bits (204), Expect = 2e-15
Identities = 48/162 (29%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQP 387
C ++ + +C+ C P YY G + PC+ + CEC P +
Sbjct: 1808 CSNDWDSYSCS-CDPGYY---GDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG 1863
Query: 388 PDCSS-----CAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P C + C G++ +P C PC C+++ C T G C CK N+
Sbjct: 1864 PYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPG------ 1917
Query: 443 YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
SP C C+C GS+S VCD G C CK GR C++C
Sbjct: 1918 --SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 80.2 bits (189), Expect = 1e-13
Identities = 57/190 (30%), Positives = 80/190 (42%), Gaps = 27/190 (14%)
Query: 353 DELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG 412
+ ++V Q C + C S C ++ CS C GY+ NC C+LN
Sbjct: 1783 ESINVEQGCSLPDPCDSNPCPANS---YCSNDWDSYSCS-CDPGYYG-DNCTN-VCDLNP 1836
Query: 413 TEGEH-CT-----PTDGLCPCKYNYAGKSCEI-----CEDGYYS-PECKNCECNTVGSVS 460
E + CT P C C NY G CE C G++ P C C C+
Sbjct: 1837 CEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFD 1896
Query: 461 YVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKA 520
C+K +G+C CK + + PTC C+C +G+ +CD GQC CK
Sbjct: 1897 PDCNKTSGECHCKENHYRPPGS---------PTCLLCDCYPTGSLSRVCDPEDGQCPCKP 1947
Query: 521 GFGGPRCDQC 530
G G +CD+C
Sbjct: 1948 GVIGRQCDRC 1957
Score = 71.7 bits (168), Expect = 5e-11
Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 15/177 (8%)
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDE-KRLSLDINGRYEGGGKCLNCQHNTEGINCN 338
S +WD +SC C+ + CT +++ + S+ G C N G
Sbjct: 1809 SNDWDSYSCS-CDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLG---P 1864
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTG-NCEEESGRCECRPEFQPPDCSSCAYGY 397
C +P + W C PC CD +C + SG C C+ P S
Sbjct: 1865 YCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGS------ 1918
Query: 398 FDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECN 454
P C C C G+ C P DG CPCK G+ C+ C++ + CE N
Sbjct: 1919 ---PTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVN 1972
Score = 70.1 bits (164), Expect = 1e-10
Identities = 73/276 (26%), Positives = 99/276 (35%), Gaps = 52/276 (18%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC 1874
C+ P P SN + S + SC+C PGY G C DL+ ++
Sbjct: 1791 CSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNVC----------DLNPCEHQ 1840
Query: 1875 KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-----CAPGFYGDAIFSKNCTA 1929
C P P +G +C N G C C G++G C
Sbjct: 1841 SVCTRK----PSAP------HGYTCECPPNYLGPYCETRIDQPCPRGWWGHP----TCGP 1886
Query: 1930 CICD-EFGM-ADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC-GIASEST 1986
C CD G DC+ T+G C C+ +H+ C C+C S S
Sbjct: 1887 CNCDVSKGFDPDCNKTSGECHCKE------------NHYRPPGSPTCLLCDCYPTGSLSR 1934
Query: 1987 QCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT----- 2039
CD ++GQC C GV G+QCD+C F T +GC+ + +C G T
Sbjct: 1935 VCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLP 1994
Query: 2040 GQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C G G C E +P C S T
Sbjct: 1995 AAAPCPKGSFGTAVRHCDEHRGWLP-PNLFNCTSIT 2029
Score = 67.7 bits (158), Expect = 7e-10
Identities = 53/195 (27%), Positives = 78/195 (40%), Gaps = 30/195 (15%)
Query: 592 SCNCDVSGSIGSTCDDNGL---CHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTAS 648
S N + S+ CD N +C +++D C +C +Y C+ +P +
Sbjct: 1784 SINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSC-SCDPGYYGDNCTNVCDLNPCEHQSV 1842
Query: 649 FAGCGSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNS 703
S P G C+C G C C +W +P C CNC+++ +
Sbjct: 1843 CTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWG----HPT-CGPCNCDVSKGFDP 1897
Query: 704 LGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
CN SG+C CK++ YR + C CDC GS+ CD G
Sbjct: 1898 --DCNKTSGECHCKEN------------HYRPPGSPT--CLLCDCYPTGSLSRVCDPEDG 1941
Query: 764 QCHCHSRVEGRRCDQ 778
QC C V GR+CD+
Sbjct: 1942 QCPCKPGVIGRQCDR 1956
Score = 67.3 bits (157), Expect = 1e-09
Identities = 60/199 (30%), Positives = 89/199 (44%), Gaps = 37/199 (18%)
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSG-SIGSTCD---- 606
P S C A+ C+ ++ C C PGYY +C + CD++ S C
Sbjct: 1794 PDPCDSNPCPANSYCS--NDWDSYSCS-CDPGYYG-DNCTNV-CDLNPCEHQSVCTRKPS 1848
Query: 607 -DNGL-CHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
+G C C N+ G C+T C ++ +P C CNCD V+ F + +GE
Sbjct: 1849 APHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCD---VSKGFDPDCNKTSGE 1905
Query: 660 LCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
C CK+ N +P +P C C+C G+L+ + C+ + GQC CK
Sbjct: 1906 -CHCKE-------NHYRP------PGSPT-CLLCDCYPTGSLSRV--CDPEDGQCPCKPG 1948
Query: 720 VGERQCDQCLDGFYRLQTN 738
V RQCD+C + F + TN
Sbjct: 1949 VIGRQCDRCDNPFAEVTTN 1967
Score = 66.1 bits (154), Expect = 2e-09
Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 25/159 (15%)
Query: 1369 TCSACRTGYYGFPNC------RPCH----CPSTAICDDNGMCICPKNVEGENCDRC--KP 1416
+CS C GYYG NC PC C C CP N G C+ +P
Sbjct: 1816 SCS-CDPGYYG-DNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQP 1873
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
+ C CNC+ G C SG+C C+EN + PG P C
Sbjct: 1874 CPRGWWGHPTCGPCNCDVSK--GFDPDCNKTSGECHCKEN------HYRPPGS---PTCL 1922
Query: 1477 QCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C G+ VCD QC CK V G+ CD C +
Sbjct: 1923 LCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPF 1961
Score = 64.1 bits (149), Expect = 9e-09
Identities = 38/115 (33%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 1356 GGQCPCKPNVIGRTCSA-----CRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGEN 1410
G C C PN +G C C G++G P C PC+C + D + C K GE
Sbjct: 1852 GYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPD----CNK-TSGE- 1905
Query: 1411 CDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHC 1465
C CK + C C+C P G + C+ + G+C C+ V GR CD C
Sbjct: 1906 C-HCKENHYRPPGSPTCLLCDCYPTGSLSR--VCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 62.9 bits (146), Expect = 2e-08
Identities = 54/170 (31%), Positives = 69/170 (40%), Gaps = 44/170 (25%)
Query: 1811 DCLICACPMPYPSNNFALSCDLS--ENGSL----------ISCNCQPGYGGARCEY---- 1854
D C+C Y +N CDL+ E+ S+ +C C P Y G CE
Sbjct: 1813 DSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQ 1872
Query: 1855 -CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLC 1913
C G++G P C PCNC + DP C+ +G+C C N +
Sbjct: 1873 PCPRGWWGHPT---------CGPCNCDVS-KGFDP-DCNKTSGEC-HCKEN------HYR 1914
Query: 1914 APGFYGDAIFSKNCTACICDEFGMAD--CDSTTGTCVCRPGVIGEKCDRC 1961
PG S C C C G CD G C C+PGVIG +CDRC
Sbjct: 1915 PPG-------SPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRC 1957
Score = 51.6 bits (118), Expect = 5e-05
Identities = 40/125 (32%), Positives = 56/125 (44%), Gaps = 27/125 (21%)
Query: 1736 CQCPRAYRGLSCEQ-----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIG 1790
C+CP Y G CE C G + P+ C PC C DV+ G +C N
Sbjct: 1855 CECPPNYLGPYCETRIDQPCPRGWWGHPT--CGPCNC-------DVSKGFDPDC--NKTS 1903
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGA 1850
C C ++ G+P CL+C C YP+ + + CD E+G C C+PG G
Sbjct: 1904 GECH-CKENHYRPP--GSPT-CLLCDC---YPTGSLSRVCD-PEDGQ---CPCKPGVIGR 1952
Query: 1851 RCEYC 1855
+C+ C
Sbjct: 1953 QCDRC 1957
Score = 50.0 bits (114), Expect = 2e-04
Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA----IC 1394
PC CD + +CN G+C CK N G P C C C T +C
Sbjct: 1886 PCNCDVSKGFDPDCNKTSGECHCKENHYRPP---------GSPTCLLCDCYPTGSLSRVC 1936
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D ++G C C V G CDRC
Sbjct: 1937 DPEDGQCPCKPGVIGRQCDRC 1957
Score = 34.7 bits (76), Expect = 6.4
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTG--TCVCRPGVIGEK 1957
++ G C C PGF GD ++ C + C G C S G TC+CR G GE
Sbjct: 1266 IHPVGGLRCR-CPPGFTGDYCETEVDLCYSRPCGPHGR--CRSREGGYTCLCRDGYTGEH 1322
Query: 1958 CD 1959
C+
Sbjct: 1323 CE 1324
Score = 34.3 bits (75), Expect = 8.4
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHC-- 418
C+C P F+ CE E C RP C S GY C C +G GEHC
Sbjct: 1274 CRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGY-------TCLCR-DGYTGEHCEV 1325
Query: 419 TPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
+ G C G +C G + +C
Sbjct: 1326 SARSGRCTPGVCKNGGTCVNLLVGGFKCDC 1355
>AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein.
Length = 491
Score = 88.6 bits (210), Expect = 4e-16
Identities = 58/189 (30%), Positives = 76/189 (40%), Gaps = 23/189 (12%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-ICEDGYYSPECKN 450
SC G + CTC GT C P +G C C + G SC+ C+ G Y C
Sbjct: 20 SCPEGLWGVNCSNTCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVP 75
Query: 451 CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAGYYNYPTCKPCNCDTSGTEPSIC 509
C+C + S+ C G C C + ++G C+Q C G++ + C C GT C
Sbjct: 76 CKC---ANHSF-CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----C 127
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNC 568
G CIC G+ G CL G + G PC C P C + G C C
Sbjct: 128 HPQDGSCICPLGWTG---HHCLEGCPLGTFGANCS-QPCQCGP----GEKCHPETGACVC 179
Query: 569 LTNFGGAQC 577
GA C
Sbjct: 180 PPGHSGAPC 188
Score = 88.2 bits (209), Expect = 5e-16
Identities = 48/162 (29%), Positives = 68/162 (41%), Gaps = 17/162 (10%)
Query: 370 GNCEEESGRCECRPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCK 428
G C E+G C C P F+ P C SC G + C PC C C P++G C C
Sbjct: 40 GTCLPENGNCVCAPGFRGPSCQRSCQPGRYG-KRCVPCKC----ANHSFCHPSNGTCYCL 94
Query: 429 YNYAGKSC-EICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQ 485
+ G C + C G++ C + C+C+ G+ C G C C ++G C + C
Sbjct: 95 AGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCLEGCP 150
Query: 486 AGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC 527
G + +PC C C +G C+C G G C
Sbjct: 151 LGTFGANCSQPCQCGPG----EKCHPETGACVCPPGHSGAPC 188
Score = 87.0 bits (206), Expect = 1e-15
Identities = 59/180 (32%), Positives = 73/180 (40%), Gaps = 24/180 (13%)
Query: 1878 NCSGNINPQDPGSCDSINGDCLKCVNNTAGAAC-NLCAPGFYGDAIFSKNCTACICDEFG 1936
NCS ++ G+C NG+C+ C G +C C PG YG K C C C
Sbjct: 29 NCSNTCTCKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYG-----KRCVPCKCANHS 82
Query: 1937 MADCDSTTGTCVCRPGVIGEKCDR-CAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC 1995
C + GTC C G G C + C P HWG N C C+ G C +G C
Sbjct: 83 F--CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTC-QCHHG-----GTCHPQDGSC 134
Query: 1996 RCAKGVTGKQC-DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKC 2053
C G TG C + C G + + C C G C+ TG C C PG G C
Sbjct: 135 ICPLGWTGHHCLEGCPLG--TFGANCSQPCQCGPGEK----CHPETGACVCPPGHSGAPC 188
Score = 80.2 bits (189), Expect = 1e-13
Identities = 59/198 (29%), Positives = 76/198 (38%), Gaps = 27/198 (13%)
Query: 431 YAGKSCEI-CEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ-CQAG 487
+ G C + C +G + C N C C G+ C G+C C + G +C + CQ G
Sbjct: 12 WMGARCHLSCPEGLWGVNCSNTCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQPG 67
Query: 488 YYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCV 546
Y C PC C S C +G C C AG+ GP C Q C G++ E
Sbjct: 68 RYG-KRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHW-----GENCAQ 117
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQC-DQCSPGYYKYPDCLSCNCDVSGSIGSTC 605
C C G T DG C C + G C + C G + C C G C
Sbjct: 118 TCQCHHGG---TCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQC----GPGEKC 170
Query: 606 -DDNGLCHCKSNFDGAKC 622
+ G C C GA C
Sbjct: 171 HPETGACVCPPGHSGAPC 188
Score = 70.9 bits (166), Expect = 8e-11
Identities = 56/199 (28%), Positives = 77/199 (38%), Gaps = 38/199 (19%)
Query: 1816 ACPMPYPSNNFALSCDLSENGSLI----SCNCQPGYGGARCE-YCAAGYYGIPEDTDLHT 1870
+CP N + +C G+ + +C C PG+ G C+ C G Y
Sbjct: 20 SCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY---------- 69
Query: 1871 GDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSKNCT- 1928
G C PC C+ + C NG C C+ G C+ C PG +G+ NC
Sbjct: 70 GKRCVPCKCANH------SFCHPSNGTCY-CLAGWTGPDCSQPCPPGHWGE-----NCAQ 117
Query: 1929 ACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQ 1987
C C G C G+C+C G G C + C +G N PC CG +
Sbjct: 118 TCQCHHGG--TCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS---QPCQCG---PGEK 169
Query: 1988 CDDDNGQCRCAKGVTGKQC 2006
C + G C C G +G C
Sbjct: 170 CHPETGACVCPPGHSGAPC 188
Score = 64.5 bits (150), Expect = 7e-09
Identities = 44/166 (26%), Positives = 58/166 (34%), Gaps = 19/166 (11%)
Query: 1366 IGRTCS-ACRTGYYGFPNCRPCHCPSTAIC-DDNGMCICPKNVEGENCDR-CKPYTFNFD 1422
+G C +C G +G C C + C +NG C+C G +C R C+P +
Sbjct: 13 MGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYG-- 70
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH-CVPGHYAFPDCYQCTCN 1481
+ C C C N C +G C C G C C PGH+ C C+
Sbjct: 71 --KRCVPCKC------ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCH 122
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQAC-DTCKEEYFNLQDDNPDGC 1526
GT C C C G C + C F P C
Sbjct: 123 HGGT----CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQC 164
Score = 53.6 bits (123), Expect = 1e-05
Identities = 54/192 (28%), Positives = 72/192 (37%), Gaps = 42/192 (21%)
Query: 254 CRCQHN-TCGPQCNKC-CS-GFEQKKWRISQNWDRFS--CEPCNCHNHTTECTYDPEIDE 308
C C++ TC P+ C C+ GF + S R+ C PC C NH+ C
Sbjct: 34 CTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSF-C-------- 84
Query: 309 KRLSLDINGRYEGGGKCLNCQHNTEGINCNK-CRPTYYRPYGKRWDELDVCQPCQCDPHF 367
+ G C C G +C++ C P + W E + Q CQC H
Sbjct: 85 ----------HPSNGTCY-CLAGWTGPDCSQPCPPGH-------WGE-NCAQTCQC--HH 123
Query: 368 STGNCEEESGRCECRPEFQPPDC-SSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCP 426
G C + G C C + C C G F +PC C GE C P G C
Sbjct: 124 G-GTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG----PGEKCHPETGACV 178
Query: 427 CKYNYAGKSCEI 438
C ++G C I
Sbjct: 179 CPPGHSGAPCRI 190
Score = 53.2 bits (122), Expect = 2e-05
Identities = 37/133 (27%), Positives = 50/133 (37%), Gaps = 16/133 (12%)
Query: 1333 YNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA-CRTGYYGFPNCRPCHCPST 1391
Y PC C + C+ G C C G CS C G++G + C C
Sbjct: 69 YGKRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG 124
Query: 1392 AICD-DNGMCICPKNVEGENC-DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
C +G CICP G +C + C TF + + C C P G + C ++G
Sbjct: 125 GTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQ---PCQCGP----GEK--CHPETG 175
Query: 1450 KCACRENVRGRVC 1462
C C G C
Sbjct: 176 ACVCPPGHSGAPC 188
Score = 52.8 bits (121), Expect = 2e-05
Identities = 44/145 (30%), Positives = 60/145 (41%), Gaps = 23/145 (15%)
Query: 1736 CQCPRAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
C C +RG SC++ C G Y CVPC+C HS C + G C A T D +
Sbjct: 49 CVCAPGFRGPSCQRSCQPGRY---GKRCVPCKCANHSF-CHPSNGTCYCLAGWTGPDCSQ 104
Query: 1795 FCMSGYHGDATVGT----------PRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQ 1844
C G+ G+ T P+D C CP+ + ++ C L G+ S CQ
Sbjct: 105 PCPPGHWGENCAQTCQCHHGGTCHPQDGS-CICPLGWTGHHCLEGCPLGTFGANCSQPCQ 163
Query: 1845 PGYGGARCE------YCAAGYYGIP 1863
G G +C C G+ G P
Sbjct: 164 CG-PGEKCHPETGACVCPPGHSGAP 187
Score = 50.8 bits (116), Expect = 9e-05
Identities = 58/208 (27%), Positives = 75/208 (36%), Gaps = 38/208 (18%)
Query: 574 GAQCD-QCSPGYYKYPDCLSCNCDVSGSIGSTC-DDNGLCHCKSNFDGAKCD-TCREQFY 630
GA+C C G + +C C G TC +NG C C F G C +C+ Y
Sbjct: 14 GARCHLSCPEGLWGVNCSNTCTC----KNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY 69
Query: 631 NYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICND-CKPLYWNLQEYNPFG 689
C C C A+ + C P+ C C G C+ C P +W
Sbjct: 70 G-KRCVPCKC------ANHSFCH--PSNGTCYCLAGWTGPDCSQPCPPGHWGEN------ 114
Query: 690 CEQ-CNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
C Q C C+ GT C+ + G C+C +G CL+G L T C C
Sbjct: 115 CAQTCQCHHGGT------CHPQDGSCICP--LGWTG-HHCLEG-CPLGTFGANCSQPCQC 164
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G C TG C C G C
Sbjct: 165 GPG----EKCHPETGACVCPPGHSGAPC 188
Score = 50.0 bits (114), Expect = 2e-04
Identities = 39/111 (35%), Positives = 48/111 (43%), Gaps = 16/111 (14%)
Query: 1951 PGV-IGEKCDRCAPDH-WGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ 2008
PG +G +C P+ WG+N CT N G C +NG C CA G G C +
Sbjct: 9 PGFWMGARCHLSCPEGLWGVNCSNTCTCKNGGT------CLPENGNCVCAPGFRGPSCQR 62
Query: 2009 -CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR-CP 2057
C G Y K C C C +S F + G C CL G G C + CP
Sbjct: 63 SCQPG--RYGKR-CVPCKC-ANHS--FCHPSNGTCYCLAGWTGPDCSQPCP 107
Score = 38.7 bits (86), Expect = 0.39
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQ-CLDGFYRLQTNDVFGCTE 745
P G NC+ T + G C ++G CVC C + C G Y + C
Sbjct: 22 PEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKR------CVP 75
Query: 746 CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C C + + C + G C+C + G C QP
Sbjct: 76 CKC----ANHSFCHPSNGTCYCLAGWTGPDCSQP 105
>X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor
protein.
Length = 750
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 291 GRCE--NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 345
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 346 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 402
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 403 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 448
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 449 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 506
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 507 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 564
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 565 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 616
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 617 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 669
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 670 CLCHVGYGGEDCGQ 683
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 203 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 259
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 260 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYTGEDCGVRSCPR 316
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 317 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 376
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 377 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 432
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 433 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 490
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 491 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 548
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 549 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 605
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 606 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 639
Score = 80.2 bits (189), Expect = 1e-13
Identities = 140/547 (25%), Positives = 188/547 (34%), Gaps = 96/547 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 201 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 258
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G N + E
Sbjct: 259 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 310
Query: 337 CNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECRP 383
C P G+ D C CDP ++ +C S GRC C P
Sbjct: 311 VRSC-PRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWP 364
Query: 384 EFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-- 437
+ DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 365 GYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CEDG 420
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPT 493
+C GY +C + C C+ G C C + YSG C C
Sbjct: 421 RCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRGR 478
Query: 494 CKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYMQ 537
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 479 CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 538
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDV 597
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 539 GLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCPN 595
Query: 598 SGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGCG 653
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 596 DCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCATR 653
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN----T 709
PA C+ + R +C C + +G E C G C
Sbjct: 654 MCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPRELC 701
Query: 710 KSGQCVC 716
++GQCVC
Sbjct: 702 RAGQCVC 708
Score = 74.5 bits (175), Expect = 6e-12
Identities = 118/425 (27%), Positives = 154/425 (36%), Gaps = 79/425 (18%)
Query: 369 TGNCEEESGRCECRPEFQPPDCSSCA-YGYFDYPNCKPCTCNLNGTEGEHCT-PTDG-LC 425
TG C S + + Q + C+ +G FD C C+C G G C+ PTD +
Sbjct: 122 TGGCCPASAQAGTGEQGQTDVRTLCSLHGVFDLSRCT-CSCE-PGWGGPTCSDPTDAEIP 179
Query: 426 PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQ 485
P A SC P+ +CN G C + G C C Y+G +C
Sbjct: 180 PSSPPSASGSC---------PD----DCNDQGR----C--VRGRCVCFPGYTGPSCG--- 217
Query: 486 AGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ--CLSGYYMQVLGRER 543
+P+C P +C G C V G C+C+AGF GP C Q C G +
Sbjct: 218 -----WPSC-PGDCQGRGR----C--VQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 265
Query: 544 QCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS 600
+CV CDP G T C S C+ +C C+PG Y DC +C S
Sbjct: 266 RCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC-VCNPG-YTGEDCGVRSCPRGCS 319
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVP 656
C D G C C + G C T C C + C C P G T + P
Sbjct: 320 QRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWP-GYTGEDCSTRTCP 377
Query: 657 AGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVC 716
C+ R GR C D + + + G C G N G C + G+CVC
Sbjct: 378 R----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC----PGDCNQRGRC--EDGRCVC 424
Query: 717 -----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRV 771
G R C + G R + G C+ G D G C R
Sbjct: 425 WPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNAGYSGE-DCGVRSCPGDCRGRGRC 479
Query: 772 EGRRC 776
E RC
Sbjct: 480 ESGRC 484
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 298 CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 354
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 355 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 413
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 414 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 467
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 468 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 520
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 521 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 577
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 578 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 625
Score = 72.1 bits (169), Expect = 3e-11
Identities = 88/337 (26%), Positives = 115/337 (34%), Gaps = 65/337 (19%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 446 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 504
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 505 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 561
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 562 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 619
Query: 482 N--QCQAGYYNYPTCKP--CNCDTSGTEPS----ICDD--------VSGQCICKAGFGGP 525
+ C + + C+ C CD T P+ +C V G C+C G+GG
Sbjct: 620 SIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE 679
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
C G+E P + P G G+C C+ F G
Sbjct: 680 DC------------GQEEP--PASACPGGCGPRELCRAGQCVCVEGFRG----------- 714
Query: 586 KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
PDC C C D G C CK + G C
Sbjct: 715 --PDCAIQTCPGDCRGRGECHD-GSCVCKDGYAGEDC 748
Score = 66.1 bits (154), Expect = 2e-09
Identities = 69/243 (28%), Positives = 93/243 (38%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 155 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 203
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 204 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 260
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G TG+ C C
Sbjct: 261 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYTGEDCGVRSC 314
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 315 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 374
Query: 2055 RCP 2057
CP
Sbjct: 375 TCP 377
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 360 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 417
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 418 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 476
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 477 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 530
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 531 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 583
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 584 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 643
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 644 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 703
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 704 -GQCVCVEGFRGPDCAIQTCP 723
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 264 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYTGEDCGVRS 313
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 314 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 365
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 366 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 420
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 421 -RCVCWPGYTGTDCGS 435
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 205 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 261
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 262 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYTGEDCGVRSCPR 316
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 317 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 372
Query: 1510 T 1510
T
Sbjct: 373 T 373
Score = 48.0 bits (109), Expect = 6e-04
Identities = 63/256 (24%), Positives = 83/256 (32%), Gaps = 50/256 (19%)
Query: 317 GRYEGGGKCLN----CQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPC----QCDPHF 367
G G G+C++ C G +C R P R +G D + VC C
Sbjct: 502 GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRS 561
Query: 368 STGNCEEES----GRCECRPEFQPPDCS--SCAYGYFDYPNCKPCTCNL-NGTEGEHCTP 420
G C GRC C + DC C + C+ C G E C+
Sbjct: 562 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI 621
Query: 421 TDGLCPCKYNYAGKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY 476
CP + G+ CE +C+ GY P C C C + G C C Y
Sbjct: 622 RT--CPSNCHGRGR-CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGY 676
Query: 477 SGRTCNQ-----------------CQAGY------YNYPTCKPCNCDTSGTEPSICDDVS 513
G C Q C+AG + P C C C D
Sbjct: 677 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHD-- 734
Query: 514 GQCICKAGFGGPRCDQ 529
G C+CK G+ G C +
Sbjct: 735 GSCVCKDGYAGEDCGE 750
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 391 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 446
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 447 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 504
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 505 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 559
Score = 43.6 bits (98), Expect = 0.014
Identities = 91/344 (26%), Positives = 114/344 (33%), Gaps = 69/344 (20%)
Query: 1736 CQCPRAYRGLSCEQCA-----EGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C A G R +G CV C + C V + G C
Sbjct: 422 CVCWPGYTGTDCGSRACPRDCRGRGRCENGVCV-CNAGYSGEDCGVRSCPGDCRGRGRCE 480
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNF-ALSC--DLSEN 1835
G C C GY G T P DC C C + + + C D +
Sbjct: 481 SG-RC-MCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 538
Query: 1836 GSLIS--CNCQPGYGGARCEY--CAAGYYGIPEDTDL-------HTGDYCK----PCNCS 1880
G C C GY G C C G G + D ++G+ C P +CS
Sbjct: 539 GLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCS 598
Query: 1881 GNINPQDPGSCDSING----DCL--KCVNNTAGAA-CN----LCAPGFYGDAIFSKNCTA 1929
+ QD G C G DC C +N G C LC PG+ G ++ C A
Sbjct: 599 QHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPA 657
Query: 1930 CICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
D G C G C+C G GE C + P P CG E +
Sbjct: 658 ---DCRGRGRC--VQGVCLCHVGYGGEDCGQEEPP-------ASACPGGCG-PRELCRA- 703
Query: 1990 DDNGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNTGYS 2031
GQC C +G G C C + C C GY+
Sbjct: 704 ---GQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYA 744
Score = 40.7 bits (91), Expect = 0.097
Identities = 64/251 (25%), Positives = 83/251 (33%), Gaps = 45/251 (17%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 515 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 572
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 573 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 631
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 632 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 691
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 692 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 737
Query: 1948 VCRPGVIGEKC 1958
VC+ G GE C
Sbjct: 738 VCKDGYAGEDC 748
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 85.4 bits (202), Expect = 3e-15
Identities = 129/527 (24%), Positives = 183/527 (34%), Gaps = 87/527 (16%)
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGR----YEGGGKCLNCQHNTEGINCNK 339
DR + C C + + T ++DE + NG G +C C EG C++
Sbjct: 486 DRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGFEGTLCDR 544
Query: 340 ----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAY 395
C P +G+ D + C C P ++ CE + C +P C
Sbjct: 545 NVDDCSPDPCH-HGRCVDGI-ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVD 602
Query: 396 GYFDYPNCKPCTCNLNGTEGEHCTPTDGLC---PCKYNYAGKSCE----ICEDGYYSPEC 448
Y C C +GT G +C C PC + +C+ G+ P C
Sbjct: 603 KYL-------CRCP-SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLC 654
Query: 449 KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN--CDTSGTEP 506
N E N S C + +C +G C C G P C P + C
Sbjct: 655 -NVEINECASSP--CGE---GGSCVDGENGFRC-LCPPGSLP-PLCLPPSHPCAHEPCSH 706
Query: 507 SICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
IC D G +C+C+ G+ GPRC Q L+ R+ C P + T CS+DG
Sbjct: 707 GICYDAPGGFRCVCEPGWSGPRCSQSLA--------RD----ACESQPCRAGGT-CSSDG 753
Query: 565 ---KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAK 621
C C G QC+ SP C C+ G S +C C + G +
Sbjct: 754 MGFHCTCPPGVQGRQCELLSP-------CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPR 806
Query: 622 CDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC----NDC-- 675
C ++ PA C P G+ + AG S C C G C NDC
Sbjct: 807 CQQDVDECAG-PA----PCGPHGICTNLAGSFS------CTCHGGYTGPSCDQDINDCDP 855
Query: 676 KPLYWNLQEYNPFGCEQCNC--NLAG--TLNSLGAC-NTKSGQCVCKQHVGERQCDQCLD 730
P + G C+C AG + C + G C HV C C
Sbjct: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTC-TCPP 914
Query: 731 GFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G+ D+ C+ C GG+ + + + C C G C
Sbjct: 915 GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFS--CLCRPGYTGAHC 959
Score = 83.0 bits (196), Expect = 2e-14
Identities = 153/585 (26%), Positives = 203/585 (34%), Gaps = 99/585 (16%)
Query: 233 CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWD-RFSC 288
C G C+ + AG CRC GP C+ C S R S D RF C
Sbjct: 87 CAGRG-VCQSSVVAGTARFS-CRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLC 144
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINCNK- 339
C C D +DE R + GG CLN C G C
Sbjct: 145 S-CPPGYQGRSCRSD--VDECR----VGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
Query: 340 ---CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYG 396
C P+ R G D+ C C P F NCE C P + + +C G
Sbjct: 198 AVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDG 254
Query: 397 YFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN--YAGKSCEICEDGYYSPECKNCECN 454
Y NC+ C T G+ CT C + N + G +C G+ +C C
Sbjct: 255 VNTY-NCQ---CPPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGH------SCVC- 302
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY-NYPTCKP---CNCDTSGT-----E 505
G C + DC + G TC+ A +Y P K C+ D + E
Sbjct: 303 VNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHE 362
Query: 506 PSICD--DVSGQ--CICKAGFGGPRCDQ----CLSGYY-MQVLGR---ERQCVPCNCDPT 553
+ICD V+G+ C C GF G CDQ C G + LGR + C C
Sbjct: 363 DAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG-R 421
Query: 554 GSTSTSCSAD------GKC----NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
G T C D G C CL G C C G+ C D+ S
Sbjct: 422 GYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC-ICMAGF----TGTYCEVDIDECQSS 476
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGEL 660
C + G+ CK +G C TC F +EC P + A C P G
Sbjct: 477 PCVNGGV--CKDRVNGFSC-TCPSGFSGSTCQLDVDECASTP---CRNGAKCVDQPDGYE 530
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C+C + +G +C+ N+ + +P C C + G + AC C+ V
Sbjct: 531 CRCAEGFEGTLCDR------NVDDCSPDPCHHGRC-VDGIASFSCACAPGYTGTRCESQV 583
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
E + C G L D + C C G+ NC+ C
Sbjct: 584 DECRSQPCRHGGKCLDLVDKYLC-RCP---SGTTGVNCEVNIDDC 624
Score = 68.9 bits (161), Expect = 3e-10
Identities = 93/370 (25%), Positives = 127/370 (34%), Gaps = 60/370 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVP------CQC---------NGHSDQCDV 1776
+C C + G +CE + GH L G CV CQC D+C +
Sbjct: 221 DCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQL 280
Query: 1777 NTGICLNCAD--NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN----NFALSC 1830
C N NT+G H C++G+ G++ DC C + +F +C
Sbjct: 281 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 340
Query: 1831 DLSENGSLI----SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP--CNCSGNIN 1884
+ + G L +C P + A C+ I TG C CS N
Sbjct: 341 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 400
Query: 1885 P-QDPGSCDSINGDCL-KCVNNTAGAAC----NLCAPG---FYGDAIFSKNCTACIC-DE 1934
P + G C + G L +C G C N C G + CIC
Sbjct: 401 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAG 460
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKC-DR-------CAPDHWGLNTGLGCTPCNCGIASEST 1986
F C+ C P V G C DR C G L C
Sbjct: 461 FTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGA 520
Query: 1987 QCDD--DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCEC 2044
+C D D +CRCA+G G CD+ + + D C H C G A+ C C
Sbjct: 521 KCVDQPDGYECRCAEGFEGTLCDR---NVDDCSPDPCHHGRCVDGI-------ASFSCAC 570
Query: 2045 LPGVIGEKCD 2054
PG G +C+
Sbjct: 571 APGYTGTRCE 580
Score = 68.9 bits (161), Expect = 3e-10
Identities = 92/342 (26%), Positives = 122/342 (35%), Gaps = 61/342 (17%)
Query: 1733 VEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ECQ G C+ G PSGF C D+C C N C D
Sbjct: 470 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFS-GSTCQLDVDECASTP--CRNGAKCVDQP 526
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C G+ G DC P P ++ ++ SC C PGY
Sbjct: 527 DGYECR-CAEGFEGTLCDRNVDDC------SPDPCHHGRCVDGIAS----FSCACAPGYT 575
Query: 1849 GARCEYCAAGYYGIP-----EDTDLHTGDYCK-PCNCSG---NINPQDPGSCDSINGDCL 1899
G RCE P + DL C+ P +G +N D S G C
Sbjct: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
+N C +C PGF G + C + C E G C+C PG +
Sbjct: 636 DGINR---YDC-VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPL 691
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN 2015
C P H PC+ GI C D G +C C G +G +C Q A
Sbjct: 692 C--LPPSH-----PCAHEPCSHGI------CYDAPGGFRCVCEPGWSGPRCSQSLA---- 734
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCD 2054
+D C+ C G + C++ G C C PGV G +C+
Sbjct: 735 --RDACESQPCRAGGT----CSSDGMGFHCTCPPGVQGRQCE 770
Score = 68.9 bits (161), Expect = 3e-10
Identities = 145/576 (25%), Positives = 195/576 (33%), Gaps = 94/576 (16%)
Query: 236 HADTCEPADPAGNLNILVCRCQHNTCGPQC----NKCCSGFEQKKWRISQNW-DRFSCEP 290
H CE A G L VC C GP+C ++C I N FSC
Sbjct: 782 HGGRCESAP--GQLP--VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC-- 835
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
CH T + D +I++ D N GG +CQ +C+ C P + P
Sbjct: 836 -TCHGGYTGPSCDQDIND----CDPNPCLNGG----SCQDGVGSFSCS-CLPGFAGPRCA 885
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEE--SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
R ++D C C P G C + S C C P + C D P+C P +C
Sbjct: 886 R--DVDECLSNPCGP----GTCTDHVASFTCTCPPGYGGFHCEQ------DLPDCSPSSC 933
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVCDK 465
GT + C C+ Y G C+ D S C + C G +
Sbjct: 934 FNGGTCVDGVNSFS--CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
TG C++ + CQ G T C C G +CD S C A G
Sbjct: 992 FTGP-QCQTLVDWCSRQPCQNGGRCVQTGAYCLCPP-GWSGRLCDIRSLPCREAAAQIGV 1049
Query: 526 RCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPG 583
R +Q C +G CV C P G T + C + C G C G
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHYCV---C-PEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1105
Query: 584 YYKYPDCLSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
Y C C + G G C+D+ C + G C ++ C+C P
Sbjct: 1106 YM-------CEC-LPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL-------CSCPP 1150
Query: 643 R--GVTASFA--GCGSVP---AGELC----QCKDRVQGRICNDCKPLYWNLQ-EYNPFGC 690
GV CG P +G C C D V G C C P Y L+ E + C
Sbjct: 1151 GTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT-CPPGYTGLRCEADINEC 1209
Query: 691 EQCNCNLAGTLNSLGACNTKSG-QCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD 749
C+ A T + L + G +C+C +C L C C
Sbjct: 1210 RSGACHAAHTRDCLQ--DPGGGFRCLCHAGFSGPRCQTVLSP-----------CESQPCQ 1256
Query: 750 IGGSIDNNCDKTTG---QCHCHSRVEGRRCDQPIRA 782
GG + G CHC G RC++ R+
Sbjct: 1257 HGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARS 1292
Score = 68.5 bits (160), Expect = 4e-10
Identities = 107/440 (24%), Positives = 138/440 (31%), Gaps = 61/440 (13%)
Query: 360 PCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEH 417
PC P G C G CEC P + +C D C C G+ +
Sbjct: 1087 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED------DVDECASQPCQHGGSCIDL 1140
Query: 418 CTPTDGLCPCKYNYAGKSCEICED--GYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
LC C G CEI ED G P C G+ C L G CTC
Sbjct: 1141 VARY--LCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT----CVDLVGGFRCTCP 1194
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLS 532
Y+G C + C+ C + T + D G +C+C AGF GPRC LS
Sbjct: 1195 PGYTGLRCEA------DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLS 1248
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Q QC P G T T C+C F G +C++ + C
Sbjct: 1249 PCESQPCQHGGQCRPSPGPGGGLTFT-------CHCAQPFWGPRCERVA------RSCRE 1295
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC 652
C V T C C G +CR + P +C C
Sbjct: 1296 LQCPVGVPCQQT-PRGPRCACPPGLSG---PSCRSFPGSPPGASNASC-AAAPCLHGGSC 1350
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA-------GTLNSLG 705
P +C QG C+ + C + C NS G
Sbjct: 1351 RPAPLAPFFRCA-CAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1409
Query: 706 ACNTKSGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGCTEC-----DCDIGGSIDNNC 758
C G C RQC+ QC F + + C DC GG + C
Sbjct: 1410 -CGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGR-ERTC 1467
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
+ + +C RCDQ
Sbjct: 1468 NPVY-EKYCADHFADGRCDQ 1486
Score = 68.1 bits (159), Expect = 6e-10
Identities = 97/377 (25%), Positives = 133/377 (35%), Gaps = 69/377 (18%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCV------PCQCNG-------HSDQCDVNT 1778
C CP+ ++G C+Q CA P G C C C+G D D +
Sbjct: 796 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
Query: 1779 GICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
CLN C D C C+ G+ G +CL C P +C +++
Sbjct: 856 NPCLNGGSCQDGVGSFSCS-CLPGFAGPRCARDVDECLSNPCG---PG-----TC--TDH 904
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPE--DTDLHTGDYCKP--CNCSGNINPQDPGS- 1890
+ +C C PGYGG CE +P+ + G C + S P G+
Sbjct: 905 VASFTCTCPPGYGGFHCE------QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAH 958
Query: 1891 CDSINGDCLK--CVNNTAGAACNLCAPGFYGDAIFSKNCTAC--ICDEFGMADCDS---- 1942
C CL C++ G C+ PGF + S C + D C +
Sbjct: 959 CQHEADPCLSRPCLH---GGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC 1015
Query: 1943 --TTGTCVCRPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAK 1999
T C+C PG G CD R P +G A +D + C C +
Sbjct: 1016 VQTGAYCLCPPGWSGRLCDIRSLPCREAA-AQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1074
Query: 2000 GVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
G TG C+Q C H GY G+M CECLPG G+ C+ +
Sbjct: 1075 GRTGSHCEQEVD---PCLAQPCQHGGTCRGYMGGYM------CECLPGYNGDNCEDDVDE 1125
Query: 2060 WVLIPQEGCLECDSCTD 2076
P C SC D
Sbjct: 1126 CASQP---CQHGGSCID 1139
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/371 (25%), Positives = 131/371 (35%), Gaps = 64/371 (17%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC+C + G C++ + C P C+ H D CA G CE
Sbjct: 530 ECRCAEGFEGTLCDRNVDD--------CSPDPCH-HGRCVDGIASFSCACAPGYTGTRCE 580
Query: 1795 F----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCD----------LSENG-S 1837
C S HG + D +C CP N ++ D + +G +
Sbjct: 581 SQVDECRSQPCRHGGKCLDLV-DKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGIN 639
Query: 1838 LISCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPCNCS-GNINPQD-PGSC 1891
C CQPG+ G C CA+ G E G+ C C G++ P P S
Sbjct: 640 RYDCVCQPGFTGPLCNVEINECASSPCG--EGGSCVDGENGFRCLCPPGSLPPLCLPPSH 697
Query: 1892 DSINGDCLK--CVNNTAGAACNLCAPGFYG----DAIFSKNCTACICDEFGMADCDSTTG 1945
+ C C + G C +C PG+ G ++ C + C G D
Sbjct: 698 PCAHEPCSHGICYDAPGGFRC-VCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF 756
Query: 1946 TCVCRPGVIGEKCDRCAP------DHWG-LNTGLGCTP-CNCGIASESTQCDDDNGQCRC 1997
C C PGV G +C+ +P +H G + G P C+C + +C D +C
Sbjct: 757 HCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDEC-A 815
Query: 1998 AKGVTGKQ--CDQCAAGF-----WNYTKDGCDH----CNCNTGYSVGFMCNATG--QCEC 2044
G C A F YT CD C+ N + G + G C C
Sbjct: 816 GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC 875
Query: 2045 LPGVIGEKCDR 2055
LPG G +C R
Sbjct: 876 LPGFAGPRCAR 886
Score = 58.4 bits (135), Expect = 5e-07
Identities = 92/360 (25%), Positives = 126/360 (35%), Gaps = 77/360 (21%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG--ICLNCADNTIGDHC 1793
C+CPR +RG C LP C+ C H +C V +C G C
Sbjct: 106 CRCPRGFRGPDCS--------LPDP-CLSSPC-AHGARCSVGPDGRFLCSCPPGYQGRSC 155
Query: 1794 ----EFCMSG---YHGDATVGTPRDCLICACPMPYPS---NNFALSCDLS---------E 1834
+ C G HG + TP C CP Y N A+ C S +
Sbjct: 156 RSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQ 214
Query: 1835 NGSL-ISCNCQPGYGGARCEY---CAAGYYGIPEDT---DLHTGDYCKPCNCSGNINPQD 1887
+G L C C PG+ G CE G+ + T ++T + P +G +D
Sbjct: 215 SGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTED 274
Query: 1888 PGSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDS 1942
C C C N G +C +C G+ G++ +C +C F A C
Sbjct: 275 VDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCSQNIDDCATAVC--FHGATCHD 331
Query: 1943 TTGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CR 1996
+ C C G G C L+ PC+ E CD + NG+ C
Sbjct: 332 RVASFYCACPMGKTGLLCH--------LDDACVSNPCH-----EDAICDTNPVNGRAICT 378
Query: 1997 CAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCD 2054
C G TG CDQ D C N +G N G C+C G G +C+
Sbjct: 379 CPPGFTGGACDQ--------DVDECS-IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE 429
Score = 52.0 bits (119), Expect = 4e-05
Identities = 97/376 (25%), Positives = 131/376 (34%), Gaps = 66/376 (17%)
Query: 1736 CQCPRAYRGLSCEQ----CAE------GHYRLPSGFCVPCQC-NGHSDQ-CDVNTGIC-- 1781
CQCP Y G CE CA G R C C G Q C+VN C
Sbjct: 183 CQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPG 242
Query: 1782 ---LN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
LN C D +C+ C + G +C + P +N +C +
Sbjct: 243 HRCLNGGTCVDGVNTYNCQ-CPPEWTGQFCTEDVDECQL----QPNACHNGG-TCFNTLG 296
Query: 1836 GSLISCNCQPGYGGARCEY----CAAG--YYGIPEDTDLHTGDYCK-PCNCSGNINPQDP 1888
G SC C G+ G C CA ++G D YC P +G + D
Sbjct: 297 GH--SCVCVNGWTGESCSQNIDDCATAVCFHGATCH-DRVASFYCACPMGKTGLLCHLDD 353
Query: 1889 GSCDS-INGDCLKCVNNTAGAACNLCAPGFYGDAIFSK--NCT--ACICDEFGMADCDST 1943
+ + D + N G A C PGF G A C+ A C+ G C +T
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGR--CVNT 411
Query: 1944 TGT--CVCRPGVIGEKCDR---------CAPDHWGLNTGLGCTPCNCGIASESTQCDDDN 1992
G+ C C G G +C+ C L+ +G C C T C+ D
Sbjct: 412 QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDR-IGQFTCICMAGFTGTYCEVDI 470
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGE 2051
+C+ + V G C GF C C +G+S G C +C P G
Sbjct: 471 DECQSSPCVNGGVCKDRVNGF---------SCTCPSGFS-GSTCQLDVDECASTPCRNGA 520
Query: 2052 KCDRCPERWVLIPQEG 2067
KC P+ + EG
Sbjct: 521 KCVDQPDGYECRCAEG 536
Score = 48.8 bits (111), Expect = 4e-04
Identities = 89/346 (25%), Positives = 116/346 (33%), Gaps = 63/346 (18%)
Query: 1736 CQCPRAYRGLSCE----QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP + G C+ C E ++ CQ G D ++ C+ C + G
Sbjct: 1022 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED-SSHYCV-CPEGRTGS 1079
Query: 1792 HCEF----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
HCE C++ HG G + C C Y +N C+ + C QP
Sbjct: 1080 HCEQEVDPCLAQPCQHGGTCRGYMGGYM-CECLPGYNGDN----CE----DDVDECASQP 1130
Query: 1846 GYGGARCEYCAAGYY-GIPEDTDLHTGDYCK--PCNCSGNINPQDPGSCDSINGDCLKCV 1902
G C A Y P T G C+ +C G P D G NG C+ V
Sbjct: 1131 CQHGGSCIDLVARYLCSCPPGT---LGVLCEINEDDC-GPGPPLDSGPRCLHNGTCVDLV 1186
Query: 1903 NNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTG---TCVCRPGVIGEK 1957
G C C PG+ G + C + C DC G C+C G G +
Sbjct: 1187 G---GFRCT-CPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPR 1242
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGK---QCDQCAAGFW 2014
C +PC ES C GQCR + G G C CA FW
Sbjct: 1243 CQTVL------------SPC------ESQPCQH-GGQCRPSPGPGGGLTFTC-HCAQPFW 1282
Query: 2015 NYTKDGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCP 2057
+ VG C T + C C PG+ G C P
Sbjct: 1283 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFP 1328
Score = 48.0 bits (109), Expect = 6e-04
Identities = 58/249 (23%), Positives = 87/249 (34%), Gaps = 27/249 (10%)
Query: 1840 SCNCQPGYGGARCEY---CAAGYY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
+C C PG+ G RC+ C +G G+ + + + G C C D D
Sbjct: 64 ACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVV-AGTARFSCRCPRGFRGPDCSLPDP 122
Query: 1894 -INGDCL---KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
++ C +C G C PG+ G ++C + + DE + + GTC+
Sbjct: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQG-----RSCRSDV-DECRVGEPCRHGGTCLN 176
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
PG +C N + C P C Q D C C G G+ C+
Sbjct: 177 TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE-- 234
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCL 2069
D C C G + N T C+C P G+ C + L P C
Sbjct: 235 ------VNVDDCPGHRCLNGGTCVDGVN-TYNCQCPPEWTGQFCTEDVDECQLQP-NACH 286
Query: 2070 ECDSCTDAL 2078
+C + L
Sbjct: 287 NGGTCFNTL 295
Score = 46.8 bits (106), Expect = 0.001
Identities = 88/350 (25%), Positives = 112/350 (32%), Gaps = 65/350 (18%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEF---CMSG-------YHGDATVGTPRDCL 1813
PC G Q CL C +G+ C+ C SG GT R
Sbjct: 48 PCANGGRCTQLPSREAACL-CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSC 106
Query: 1814 ICA-------CPMPYPSNNFALS----CDLSENGSLISCNCQPGYGGARC----EYCAAG 1858
C C +P P + + C + +G + C+C PGY G C + C G
Sbjct: 107 RCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFL-CSCPPGYQGRSCRSDVDECRVG 165
Query: 1859 YYGIPEDTDLHT-GDYCKPCN-------CSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
T L+T G + C C P P C + G C + + T AC
Sbjct: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRN-GGTCRQSGDLTYDCAC 224
Query: 1911 NLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC----DRCA-- 1962
PGF G + +C C G T C C P G+ C D C
Sbjct: 225 ---LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 281
Query: 1963 PD--HWG---LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
P+ H G NT LG C C C + C A G C A F+
Sbjct: 282 PNACHNGGTCFNT-LGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 340
Query: 2018 KDG-----C---DHCNCNTGYSVGFM----CNATGQCECLPGVIGEKCDR 2055
G C D C N + N C C PG G CD+
Sbjct: 341 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ 390
Score = 45.6 bits (103), Expect = 0.003
Identities = 76/296 (25%), Positives = 102/296 (34%), Gaps = 46/296 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC-DVNTGICLNCADNTIGDHCE 1794
C+C Y G +CE + PCQ H C D+ +C T+G CE
Sbjct: 1108 CECLPGYNGDNCEDDVD------ECASQPCQ---HGGSCIDLVARYLCSCPPGTLGVLCE 1158
Query: 1795 F----CMSGYHGDATV-----GTPRDCL---ICACPMPYPSNNFALSCDLSENGSLIS-- 1840
C G D+ GT D + C CP Y + +G+ +
Sbjct: 1159 INEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAH 1218
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD 1897
C PG GG RC C AG+ G T L + +PC G P PG +
Sbjct: 1219 TRDCLQDPG-GGFRC-LCHAGFSGPRCQTVLSPCE-SQPCQHGGQCRPS-PGPGGGLTFT 1274
Query: 1898 CLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGT-CVCRPGVIGE 1956
C C G C A ++C C G+ + G C C PG+ G
Sbjct: 1275 C-HCAQPFWGPRCERVA----------RSCRELQCP-VGVPCQQTPRGPRCACPPGLSGP 1322
Query: 1957 KCDRCAPDHWGL-NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAA 2011
C G N PC G + +C CA+G TG +C+ AA
Sbjct: 1323 SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFF-RCACAQGWTGPRCEAPAA 1377
Score = 44.4 bits (100), Expect = 0.008
Identities = 59/247 (23%), Positives = 84/247 (34%), Gaps = 45/247 (18%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQC---PCKPNV-----IGRTCSACRTGYYG------FP 1381
G+ C C G T C T +C PC+ IG+ C G+ G
Sbjct: 413 GSFLCQCG-RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDID 471
Query: 1382 NCRPCHCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVV 1438
C+ C + +C D NG C CP G C DV D+C P
Sbjct: 472 ECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ--------LDV----DECASTPCRN- 518
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDH----CVPGHYAFPDC------YQCTCNRHGTTYD 1488
G + + D +C C E G +CD C P C + C C G T
Sbjct: 519 GAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCAC-APGYTGT 577
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI 1548
C+ +C + G C ++Y P G T C C+S+ T+
Sbjct: 578 RCESQVDECRSQPCRHGGKCLDLVDKYL---CRCPSGTTGVNCEVNIDDCASNPCTFGVC 634
Query: 1549 DEMVDWY 1555
+ ++ Y
Sbjct: 635 RDGINRY 641
Score = 44.4 bits (100), Expect = 0.008
Identities = 44/164 (26%), Positives = 62/164 (37%), Gaps = 25/164 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGM-CICPKNVEGENCDRC 1414
G +C C+P G CS +PC T D G C CP V+G C+
Sbjct: 715 GFRCVCEPGWSGPRCSQSLAR--DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL 772
Query: 1415 KPYTFNFDVQRG-CDD-------CNCNPLGVVGNQLQCEAD--SGKCACRENVRGRVCDH 1464
P T N G C+ C+C P G G + Q + D +G C + +C +
Sbjct: 773 SPCTPNPCEHGGRCESAPGQLPVCSC-PQGWQGPRCQQDVDECAGPAPCGPH---GICTN 828
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ CTC+ G T CDQ+ C + G +C
Sbjct: 829 -------LAGSFSCTCH-GGYTGPSCDQDINDCDPNPCLNGGSC 864
Score = 42.7 bits (96), Expect = 0.024
Identities = 77/334 (23%), Positives = 111/334 (33%), Gaps = 49/334 (14%)
Query: 320 EGGGKCLN---CQHNTEGINCNKCRPTYYRPYGKRWD-ELDVCQPCQCDPHFSTGNCEEE 375
+ G +CL+ C G C C P Y G R + +++ C+ C T +C ++
Sbjct: 1171 DSGPRCLHNGTCVDLVGGFRCT-CPPGYT---GLRCEADINECRSGACHAAH-TRDCLQD 1225
Query: 376 SG---RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
G RC C F P C + P C + G T T C C +
Sbjct: 1226 PGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFT---CHCAQPFW 1282
Query: 433 GKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQA---G 487
G CE + C+ +C V C + C C SG +C G
Sbjct: 1283 GPRCE-----RVARSCRELQC----PVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPG 1333
Query: 488 YYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD------------QCLSGYY 535
N +C C G+ +C C G+ GPRC+ +C
Sbjct: 1334 ASN-ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAAC 1392
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCSAD-----GKCNCLTNFGGAQCDQCSPGYYKYPDC 590
G +R CN G CS +C L + +C P P C
Sbjct: 1393 QAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPA-CSSPAC 1451
Query: 591 LSCNCDV-SGSIGSTCDDNGLCHCKSNFDGAKCD 623
L N D +G TC+ +C +F +CD
Sbjct: 1452 LYDNFDCHAGGRERTCNPVYEKYCADHFADGRCD 1485
Score = 40.3 bits (90), Expect = 0.13
Identities = 79/301 (26%), Positives = 97/301 (32%), Gaps = 59/301 (19%)
Query: 516 CICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
C+C G+ G RC D C SG GR C S+ + +A C C F
Sbjct: 65 CLCPPGWVGERCQLEDPCHSG---PCAGRG----VCQ-----SSVVAGTARFSCRCPRGF 112
Query: 573 GGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR-- 626
G C P CLS C D LC C + G C D CR
Sbjct: 113 RGPDCSLPDP-------CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 165
Query: 627 ------EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKD----RVQGRICNDCK 676
N P C C P G T +VP C++ R G + DC
Sbjct: 166 EPCRHGGTCLNTPGSFRCQC-PAGYTGPLCENPAVPCAP-SPCRNGGTCRQSGDLTYDCA 223
Query: 677 --PLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQC-------VCKQHVGERQC- 725
P + E N C C GT + NT + QC C + V E Q
Sbjct: 224 CLPGFEGQNCEVNVDDCPGHRCLNGGT--CVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 281
Query: 726 -DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDK-TTGQCH----CHSRVEGRRCDQP 779
+ C +G T C + G S N D T C CH RV C P
Sbjct: 282 PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP 341
Query: 780 I 780
+
Sbjct: 342 M 342
Score = 39.9 bits (89), Expect = 0.17
Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 29/189 (15%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG 1398
PCL GS + +F C C P G C+ P C P C +
Sbjct: 857 PCLNG--GSCQDGVGSFS--CSCLPGFAGPRCARDVDECLSNP-CGPGTCTDHVA---SF 908
Query: 1399 MCICPKNVEGENCDR----CKPYT-FNFDV-QRGCDD--CNCNPLGVVGNQLQCEADSGK 1450
C CP G +C++ C P + FN G + C C P G G Q EAD
Sbjct: 909 TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP-GYTGAHCQHEADP-- 965
Query: 1451 CACRENVRGRVCDHCVPG-------HYAFPDCYQCT--CNRHG-TTYDVCDQNTAQCYCK 1500
C R + G VC PG + P C C+R C Q A C C
Sbjct: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP 1025
Query: 1501 TNVRGQACD 1509
G+ CD
Sbjct: 1026 PGWSGRLCD 1034
Score = 35.9 bits (79), Expect = 2.8
Identities = 52/208 (25%), Positives = 70/208 (33%), Gaps = 30/208 (14%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA----CR--TGYYGFPNCRPCHCPSTAICDDNG-MCICPK 1404
C G C C P GR C CR G + C + +D+ C+CP+
Sbjct: 1015 CVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1074
Query: 1405 NVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQCEADSGKCACREN 1456
G +C++ Q G C C C P G G+ CE D +CA +
Sbjct: 1075 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLP-GYNGD--NCEDDVDECASQPC 1131
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV-RGQAC---DTCK 1512
G C V Y C+C GT +C+ N C + G C TC
Sbjct: 1132 QHGGSCIDLVAR-------YLCSC-PPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
Query: 1513 EEYFNLQDDNPDGCTKCFCFGKTTRCSS 1540
+ + P G T C C S
Sbjct: 1184 DLVGGFRCTCPPGYTGLRCEADINECRS 1211
Score = 34.7 bits (76), Expect = 6.4
Identities = 44/169 (26%), Positives = 55/169 (32%), Gaps = 26/169 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYY----GFPNCRPCHCPSTAICDDNGM----CICPKNVE 1407
GG C P C A TG P C P C + C +G C C E
Sbjct: 171 GGTCLNTPGSFRCQCPAGYTGPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFE 229
Query: 1408 GENC----DRCKPYTF--NFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV--RG 1459
G+NC D C + G + NC Q C D +C + N G
Sbjct: 230 GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQF-CTEDVDECQLQPNACHNG 288
Query: 1460 RVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C + + GH C C +G T + C QN C G C
Sbjct: 289 GTCFNTLGGH-------SCVC-VNGWTGESCSQNIDDCATAVCFHGATC 329
>U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein.
Length = 4289
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 288 GRCE--NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 342
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 343 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 399
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 400 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 503
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 504 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 561
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 562 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 613
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 614 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 666
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 667 CLCHVGYGGEDCGQ 680
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 256
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 257 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYTGEDCGVRSCPR 313
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 314 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 373
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 374 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 429
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 430 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 487
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 488 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 545
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 602
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 603 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 636
Score = 80.2 bits (189), Expect = 1e-13
Identities = 140/547 (25%), Positives = 188/547 (34%), Gaps = 96/547 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 198 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 255
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G N + E
Sbjct: 256 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
Query: 337 CNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECRP 383
C P G+ D C CDP ++ +C S GRC C P
Sbjct: 308 VRSC-PRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWP 361
Query: 384 EFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-- 437
+ DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 362 GYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CEDG 417
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPT 493
+C GY +C + C C+ G C C + YSG C C
Sbjct: 418 RCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRGR 475
Query: 494 CKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYMQ 537
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 476 CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 535
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDV 597
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 536 GLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCPN 592
Query: 598 SGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGCG 653
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 593 DCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCATR 650
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN----T 709
PA C+ + R +C C + +G E C G C
Sbjct: 651 MCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPRELC 698
Query: 710 KSGQCVC 716
++GQCVC
Sbjct: 699 RAGQCVC 705
Score = 77.8 bits (183), Expect = 7e-13
Identities = 92/332 (27%), Positives = 118/332 (35%), Gaps = 47/332 (14%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 443 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 558
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 616
Query: 482 NQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR 541
+ TC P NC G C++ G+C+C G+ GP C + + GR
Sbjct: 617 S--------IRTC-PSNCHGRGR----CEE--GRCLCDPGYTGPTCATRMCPADCRGRGR 661
Query: 542 ERQCVPCNC------DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q V C C + G SA G C QC C G+ + PDC
Sbjct: 662 CVQGV-CLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQC-VCVEGF-RGPDCAIQT 718
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCR 626
C C D G C CK + G C R
Sbjct: 719 CPGDCRGRGECHD-GSCVCKDGYAGEDCGEAR 749
Score = 73.3 bits (172), Expect = 1e-11
Identities = 105/388 (27%), Positives = 139/388 (35%), Gaps = 68/388 (17%)
Query: 408 CNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDK- 465
C+L+G + CT C C+ + G +C D P + GS C+
Sbjct: 143 CSLHGVFDLSRCT-----CSCEPGWGGPTCSDPTDAEIPPSSPP---SASGSCPDDCNDQ 194
Query: 466 ---LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
+ G C C Y+G +C +P+C P +C G C V G C+C+AGF
Sbjct: 195 GRCVRGRCVCFPGYTGPSCG--------WPSC-PGDCQGRGR----C--VQGVCVCRAGF 239
Query: 523 GGPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQC 577
GP C Q C G + +CV CDP G T C S C+ +C
Sbjct: 240 SGPDCSQRSCPRGCSQRGRCEGGRCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC 295
Query: 578 DQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPAC 635
C+PG Y DC +C S C D G C C + G C T C C
Sbjct: 296 -VCNPG-YTGEDCGVRSCPRGCSQRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 636 EE--CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
+ C C P G T + P C+ R GR C D + + + G C
Sbjct: 353 VDGRCVCWP-GYTGEDCSTRTCPR----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC 404
Query: 694 NCNLAGTLNSLGACNTKSGQCVC-----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
G N G C + G+CVC G R C + G R + G C+
Sbjct: 405 ----PGDCNQRGRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNA 454
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G D G C R E RC
Sbjct: 455 GYSGE-DCGVRSCPGDCRGRGRCESGRC 481
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 295 CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 351
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 352 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 410
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 411 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 464
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 465 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 517
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 518 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 574
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 575 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 622
Score = 66.1 bits (154), Expect = 2e-09
Identities = 69/243 (28%), Positives = 93/243 (38%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 152 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 200
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 201 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G TG+ C C
Sbjct: 258 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYTGEDCGVRSC 311
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 312 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 371
Query: 2055 RCP 2057
CP
Sbjct: 372 TCP 374
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 414
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 415 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 473
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 474 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 527
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 528 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 580
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 581 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 640
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 641 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 700
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 701 -GQCVCVEGFRGPDCAIQTCP 720
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 261 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYTGEDCGVRS 310
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 311 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 362
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 363 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 417
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 418 -RCVCWPGYTGTDCGS 432
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 202 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 258
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 259 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYTGEDCGVRSCPR 313
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 314 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 369
Query: 1510 T 1510
T
Sbjct: 370 T 370
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 388 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 443
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 444 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 501
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 502 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 556
Score = 43.6 bits (98), Expect = 0.014
Identities = 91/344 (26%), Positives = 114/344 (33%), Gaps = 69/344 (20%)
Query: 1736 CQCPRAYRGLSCEQCA-----EGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C A G R +G CV C + C V + G C
Sbjct: 419 CVCWPGYTGTDCGSRACPRDCRGRGRCENGVCV-CNAGYSGEDCGVRSCPGDCRGRGRCE 477
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNF-ALSC--DLSEN 1835
G C C GY G T P DC C C + + + C D +
Sbjct: 478 SG-RC-MCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 535
Query: 1836 GSLIS--CNCQPGYGGARCEY--CAAGYYGIPEDTDL-------HTGDYCK----PCNCS 1880
G C C GY G C C G G + D ++G+ C P +CS
Sbjct: 536 GLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCS 595
Query: 1881 GNINPQDPGSCDSING----DCL--KCVNNTAGAA-CN----LCAPGFYGDAIFSKNCTA 1929
+ QD G C G DC C +N G C LC PG+ G ++ C A
Sbjct: 596 QHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPA 654
Query: 1930 CICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
D G C G C+C G GE C + P P CG E +
Sbjct: 655 ---DCRGRGRC--VQGVCLCHVGYGGEDCGQEEPP-------ASACPGGCG-PRELCRA- 700
Query: 1990 DDNGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNTGYS 2031
GQC C +G G C C + C C GY+
Sbjct: 701 ---GQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYA 741
Score = 40.7 bits (91), Expect = 0.097
Identities = 64/251 (25%), Positives = 83/251 (33%), Gaps = 45/251 (17%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 569
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 570 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 628
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 629 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 688
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 689 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 734
Query: 1948 VCRPGVIGEKC 1958
VC+ G GE C
Sbjct: 735 VCKDGYAGEDC 745
>AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 288 GRCE--NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 342
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 343 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 399
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 400 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 503
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 504 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 561
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 562 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 613
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 614 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 666
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 667 CLCHVGYGGEDCGQ 680
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 256
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 257 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYTGEDCGVRSCPR 313
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 314 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 373
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 374 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 429
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 430 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 487
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 488 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 545
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 602
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 603 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 636
Score = 80.2 bits (189), Expect = 1e-13
Identities = 140/547 (25%), Positives = 188/547 (34%), Gaps = 96/547 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 198 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 255
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G N + E
Sbjct: 256 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
Query: 337 CNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECRP 383
C P G+ D C CDP ++ +C S GRC C P
Sbjct: 308 VRSC-PRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWP 361
Query: 384 EFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-- 437
+ DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 362 GYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CEDG 417
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPT 493
+C GY +C + C C+ G C C + YSG C C
Sbjct: 418 RCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRGR 475
Query: 494 CKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYMQ 537
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 476 CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 535
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDV 597
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 536 GLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCPN 592
Query: 598 SGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGCG 653
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 593 DCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCATR 650
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN----T 709
PA C+ + R +C C + +G E C G C
Sbjct: 651 MCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPRELC 698
Query: 710 KSGQCVC 716
++GQCVC
Sbjct: 699 RAGQCVC 705
Score = 73.3 bits (172), Expect = 1e-11
Identities = 105/388 (27%), Positives = 139/388 (35%), Gaps = 68/388 (17%)
Query: 408 CNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDK- 465
C+L+G + CT C C+ + G +C D P + GS C+
Sbjct: 143 CSLHGVFDLSRCT-----CSCEPGWGGPTCSDPTDAEIPPSSPP---SASGSCPDDCNDQ 194
Query: 466 ---LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
+ G C C Y+G +C +P+C P +C G C V G C+C+AGF
Sbjct: 195 GRCVRGRCVCFPGYTGPSCG--------WPSC-PGDCQGRGR----C--VQGVCVCRAGF 239
Query: 523 GGPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQC 577
GP C Q C G + +CV CDP G T C S C+ +C
Sbjct: 240 SGPDCSQRSCPRGCSQRGRCEGGRCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC 295
Query: 578 DQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPAC 635
C+PG Y DC +C S C D G C C + G C T C C
Sbjct: 296 -VCNPG-YTGEDCGVRSCPRGCSQRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 636 EE--CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
+ C C P G T + P C+ R GR C D + + + G C
Sbjct: 353 VDGRCVCWP-GYTGEDCSTRTCPR----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC 404
Query: 694 NCNLAGTLNSLGACNTKSGQCVC-----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
G N G C + G+CVC G R C + G R + G C+
Sbjct: 405 ----PGDCNQRGRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNA 454
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G D G C R E RC
Sbjct: 455 GYSGE-DCGVRSCPGDCRGRGRCESGRC 481
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 295 CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 351
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 352 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 410
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 411 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 464
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 465 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 517
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 518 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 574
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 575 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 622
Score = 72.1 bits (169), Expect = 3e-11
Identities = 88/337 (26%), Positives = 115/337 (34%), Gaps = 65/337 (19%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 443 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 558
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 616
Query: 482 N--QCQAGYYNYPTCKP--CNCDTSGTEPS----ICDD--------VSGQCICKAGFGGP 525
+ C + + C+ C CD T P+ +C V G C+C G+GG
Sbjct: 617 SIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE 676
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
C G+E P + P G G+C C+ F G
Sbjct: 677 DC------------GQEEP--PASACPGGCGPRELCRAGQCVCVEGFRG----------- 711
Query: 586 KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
PDC C C D G C CK + G C
Sbjct: 712 --PDCAIQTCPGDCRGRGECHD-GSCVCKDGYAGEDC 745
Score = 66.1 bits (154), Expect = 2e-09
Identities = 69/243 (28%), Positives = 93/243 (38%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 152 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 200
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 201 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G TG+ C C
Sbjct: 258 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYTGEDCGVRSC 311
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 312 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 371
Query: 2055 RCP 2057
CP
Sbjct: 372 TCP 374
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 414
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 415 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 473
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 474 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 527
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 528 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 580
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 581 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 640
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 641 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 700
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 701 -GQCVCVEGFRGPDCAIQTCP 720
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 261 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYTGEDCGVRS 310
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 311 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 362
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 363 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 417
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 418 -RCVCWPGYTGTDCGS 432
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 202 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 258
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 259 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYTGEDCGVRSCPR 313
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 314 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 369
Query: 1510 T 1510
T
Sbjct: 370 T 370
Score = 48.0 bits (109), Expect = 6e-04
Identities = 63/256 (24%), Positives = 83/256 (32%), Gaps = 50/256 (19%)
Query: 317 GRYEGGGKCLN----CQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPC----QCDPHF 367
G G G+C++ C G +C R P R +G D + VC C
Sbjct: 499 GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRS 558
Query: 368 STGNCEEES----GRCECRPEFQPPDCS--SCAYGYFDYPNCKPCTCNL-NGTEGEHCTP 420
G C GRC C + DC C + C+ C G E C+
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI 618
Query: 421 TDGLCPCKYNYAGKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY 476
CP + G+ CE +C+ GY P C C C + G C C Y
Sbjct: 619 RT--CPSNCHGRGR-CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGY 673
Query: 477 SGRTCNQ-----------------CQAGY------YNYPTCKPCNCDTSGTEPSICDDVS 513
G C Q C+AG + P C C C D
Sbjct: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHD-- 731
Query: 514 GQCICKAGFGGPRCDQ 529
G C+CK G+ G C +
Sbjct: 732 GSCVCKDGYAGEDCGE 747
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 388 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 443
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 444 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 501
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 502 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 556
Score = 42.3 bits (95), Expect = 0.032
Identities = 67/265 (25%), Positives = 87/265 (32%), Gaps = 45/265 (16%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 569
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 570 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 628
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 629 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 688
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 689 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 734
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGL 1972
VC+ G GE C P G+ L
Sbjct: 735 VCKDGYAGEDCGEEVPTIEGMRMHL 759
>AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 288 GRCE--NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 342
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 343 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 399
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 400 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 503
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 504 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 561
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 562 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 613
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 614 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 666
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 667 CLCHVGYGGEDCGQ 680
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 256
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 257 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYTGEDCGVRSCPR 313
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 314 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 373
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 374 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 429
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 430 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 487
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 488 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 545
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 602
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 603 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 636
Score = 80.2 bits (189), Expect = 1e-13
Identities = 140/547 (25%), Positives = 188/547 (34%), Gaps = 96/547 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 198 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 255
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G N + E
Sbjct: 256 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
Query: 337 CNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECRP 383
C P G+ D C CDP ++ +C S GRC C P
Sbjct: 308 VRSC-PRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWP 361
Query: 384 EFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-- 437
+ DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 362 GYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CEDG 417
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPT 493
+C GY +C + C C+ G C C + YSG C C
Sbjct: 418 RCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRGR 475
Query: 494 CKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYMQ 537
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 476 CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 535
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDV 597
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 536 GLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCPN 592
Query: 598 SGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGCG 653
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 593 DCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCATR 650
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN----T 709
PA C+ + R +C C + +G E C G C
Sbjct: 651 MCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPRELC 698
Query: 710 KSGQCVC 716
++GQCVC
Sbjct: 699 RAGQCVC 705
Score = 73.3 bits (172), Expect = 1e-11
Identities = 105/388 (27%), Positives = 139/388 (35%), Gaps = 68/388 (17%)
Query: 408 CNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDK- 465
C+L+G + CT C C+ + G +C D P + GS C+
Sbjct: 143 CSLHGVFDLSRCT-----CSCEPGWGGPTCSDPTDAEIPPSSPP---SASGSCPDDCNDQ 194
Query: 466 ---LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
+ G C C Y+G +C +P+C P +C G C V G C+C+AGF
Sbjct: 195 GRCVRGRCVCFPGYTGPSCG--------WPSC-PGDCQGRGR----C--VQGVCVCRAGF 239
Query: 523 GGPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQC 577
GP C Q C G + +CV CDP G T C S C+ +C
Sbjct: 240 SGPDCSQRSCPRGCSQRGRCEGGRCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC 295
Query: 578 DQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPAC 635
C+PG Y DC +C S C D G C C + G C T C C
Sbjct: 296 -VCNPG-YTGEDCGVRSCPRGCSQRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 636 EE--CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
+ C C P G T + P C+ R GR C D + + + G C
Sbjct: 353 VDGRCVCWP-GYTGEDCSTRTCPR----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC 404
Query: 694 NCNLAGTLNSLGACNTKSGQCVC-----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
G N G C + G+CVC G R C + G R + G C+
Sbjct: 405 ----PGDCNQRGRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNA 454
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G D G C R E RC
Sbjct: 455 GYSGE-DCGVRSCPGDCRGRGRCESGRC 481
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 295 CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 351
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 352 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 410
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 411 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 464
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 465 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 517
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 518 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 574
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 575 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 622
Score = 72.1 bits (169), Expect = 3e-11
Identities = 88/337 (26%), Positives = 115/337 (34%), Gaps = 65/337 (19%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 443 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 558
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 616
Query: 482 N--QCQAGYYNYPTCKP--CNCDTSGTEPS----ICDD--------VSGQCICKAGFGGP 525
+ C + + C+ C CD T P+ +C V G C+C G+GG
Sbjct: 617 SIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE 676
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
C G+E P + P G G+C C+ F G
Sbjct: 677 DC------------GQEEP--PASACPGGCGPRELCRAGQCVCVEGFRG----------- 711
Query: 586 KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
PDC C C D G C CK + G C
Sbjct: 712 --PDCAIQTCPGDCRGRGECHD-GSCVCKDGYAGEDC 745
Score = 66.1 bits (154), Expect = 2e-09
Identities = 69/243 (28%), Positives = 93/243 (38%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 152 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 200
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 201 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G TG+ C C
Sbjct: 258 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYTGEDCGVRSC 311
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 312 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 371
Query: 2055 RCP 2057
CP
Sbjct: 372 TCP 374
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 414
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 415 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 473
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 474 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 527
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 528 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 580
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 581 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 640
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 641 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 700
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 701 -GQCVCVEGFRGPDCAIQTCP 720
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 261 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYTGEDCGVRS 310
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 311 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 362
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 363 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 417
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 418 -RCVCWPGYTGTDCGS 432
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 202 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 258
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 259 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYTGEDCGVRSCPR 313
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 314 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 369
Query: 1510 T 1510
T
Sbjct: 370 T 370
Score = 48.0 bits (109), Expect = 6e-04
Identities = 63/256 (24%), Positives = 83/256 (32%), Gaps = 50/256 (19%)
Query: 317 GRYEGGGKCLN----CQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPC----QCDPHF 367
G G G+C++ C G +C R P R +G D + VC C
Sbjct: 499 GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRS 558
Query: 368 STGNCEEES----GRCECRPEFQPPDCS--SCAYGYFDYPNCKPCTCNL-NGTEGEHCTP 420
G C GRC C + DC C + C+ C G E C+
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI 618
Query: 421 TDGLCPCKYNYAGKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY 476
CP + G+ CE +C+ GY P C C C + G C C Y
Sbjct: 619 RT--CPSNCHGRGR-CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGY 673
Query: 477 SGRTCNQ-----------------CQAGY------YNYPTCKPCNCDTSGTEPSICDDVS 513
G C Q C+AG + P C C C D
Sbjct: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHD-- 731
Query: 514 GQCICKAGFGGPRCDQ 529
G C+CK G+ G C +
Sbjct: 732 GSCVCKDGYAGEDCGE 747
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 388 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 443
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 444 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 501
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 502 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 556
Score = 42.3 bits (95), Expect = 0.032
Identities = 67/265 (25%), Positives = 87/265 (32%), Gaps = 45/265 (16%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 569
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 570 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 628
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 629 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 688
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 689 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 734
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGL 1972
VC+ G GE C P G+ L
Sbjct: 735 VCKDGYAGEDCGEEVPTIEGMRMHL 759
>AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 288 GRCE--NGRCVCNPGYAGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 342
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 343 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 399
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 400 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 503
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 504 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 561
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 562 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 613
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 614 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 666
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 667 CLCHVGYGGEDCGQ 680
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 256
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 257 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYAGEDCGVRSCPR 313
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 314 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 373
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 374 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 429
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 430 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 487
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 488 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 545
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 602
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 603 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 636
Score = 80.2 bits (189), Expect = 1e-13
Identities = 141/548 (25%), Positives = 192/548 (35%), Gaps = 98/548 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 198 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 255
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G +C+ C G +
Sbjct: 256 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENG-RCV-CNPGYAGED 305
Query: 337 CN-KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECR 382
C + P G+ D C CDP ++ +C S GRC C
Sbjct: 306 CGVRSCPRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW 360
Query: 383 PEFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
P + DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 361 PGYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CED 416
Query: 438 ---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYP 492
+C GY +C + C C+ G C C + YSG C C
Sbjct: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRG 474
Query: 493 TCKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYM 536
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 475 RCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRG 534
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCD 596
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 535 HGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCP 591
Query: 597 VSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGC 652
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 592 NDCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCAT 649
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN---- 708
PA C+ + R +C C + +G E C G C
Sbjct: 650 RMCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPREL 697
Query: 709 TKSGQCVC 716
++GQCVC
Sbjct: 698 CRAGQCVC 705
Score = 73.3 bits (172), Expect = 1e-11
Identities = 105/388 (27%), Positives = 139/388 (35%), Gaps = 68/388 (17%)
Query: 408 CNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDK- 465
C+L+G + CT C C+ + G +C D P + GS C+
Sbjct: 143 CSLHGVFDLSRCT-----CSCEPGWGGPTCSDPTDAEIPPSSPP---SASGSCPDDCNDQ 194
Query: 466 ---LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
+ G C C Y+G +C +P+C P +C G C V G C+C+AGF
Sbjct: 195 GRCVRGRCVCFPGYTGPSCG--------WPSC-PGDCQGRGR----C--VQGVCVCRAGF 239
Query: 523 GGPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQC 577
GP C Q C G + +CV CDP G T C S C+ +C
Sbjct: 240 SGPDCSQRSCPRGCSQRGRCEGGRCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC 295
Query: 578 DQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPAC 635
C+PG Y DC +C S C D G C C + G C T C C
Sbjct: 296 -VCNPG-YAGEDCGVRSCPRGCSQRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 636 EE--CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
+ C C P G T + P C+ R GR C D + + + G C
Sbjct: 353 VDGRCVCWP-GYTGEDCSTRTCPR----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC 404
Query: 694 NCNLAGTLNSLGACNTKSGQCVC-----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
G N G C + G+CVC G R C + G R + G C+
Sbjct: 405 ----PGDCNQRGRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNA 454
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G D G C R E RC
Sbjct: 455 GYSGE-DCGVRSCPGDCRGRGRCESGRC 481
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 295 CVCNPGYAGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 351
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 352 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 410
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 411 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 464
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 465 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 517
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 518 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 574
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 575 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 622
Score = 72.1 bits (169), Expect = 3e-11
Identities = 88/337 (26%), Positives = 115/337 (34%), Gaps = 65/337 (19%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 443 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 558
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 616
Query: 482 N--QCQAGYYNYPTCKP--CNCDTSGTEPS----ICDD--------VSGQCICKAGFGGP 525
+ C + + C+ C CD T P+ +C V G C+C G+GG
Sbjct: 617 SIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE 676
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
C G+E P + P G G+C C+ F G
Sbjct: 677 DC------------GQEEP--PASACPGGCGPRELCRAGQCVCVEGFRG----------- 711
Query: 586 KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
PDC C C D G C CK + G C
Sbjct: 712 --PDCAIQTCPGDCRGRGECHD-GSCVCKDGYAGEDC 745
Score = 64.1 bits (149), Expect = 9e-09
Identities = 68/243 (27%), Positives = 92/243 (37%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 152 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 200
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 201 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G G+ C C
Sbjct: 258 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYAGEDCGVRSC 311
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 312 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 371
Query: 2055 RCP 2057
CP
Sbjct: 372 TCP 374
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 414
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 415 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 473
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 474 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 527
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 528 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 580
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 581 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 640
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 641 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 700
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 701 -GQCVCVEGFRGPDCAIQTCP 720
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 261 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYAGEDCGVRS 310
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 311 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 362
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 363 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 417
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 418 -RCVCWPGYTGTDCGS 432
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 202 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 258
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 259 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYAGEDCGVRSCPR 313
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 314 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 369
Query: 1510 T 1510
T
Sbjct: 370 T 370
Score = 48.0 bits (109), Expect = 6e-04
Identities = 63/256 (24%), Positives = 83/256 (32%), Gaps = 50/256 (19%)
Query: 317 GRYEGGGKCLN----CQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPC----QCDPHF 367
G G G+C++ C G +C R P R +G D + VC C
Sbjct: 499 GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRS 558
Query: 368 STGNCEEES----GRCECRPEFQPPDCS--SCAYGYFDYPNCKPCTCNL-NGTEGEHCTP 420
G C GRC C + DC C + C+ C G E C+
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI 618
Query: 421 TDGLCPCKYNYAGKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY 476
CP + G+ CE +C+ GY P C C C + G C C Y
Sbjct: 619 RT--CPSNCHGRGR-CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGY 673
Query: 477 SGRTCNQ-----------------CQAGY------YNYPTCKPCNCDTSGTEPSICDDVS 513
G C Q C+AG + P C C C D
Sbjct: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHD-- 731
Query: 514 GQCICKAGFGGPRCDQ 529
G C+CK G+ G C +
Sbjct: 732 GSCVCKDGYAGEDCGE 747
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 388 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 443
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 444 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 501
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 502 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 556
Score = 42.3 bits (95), Expect = 0.032
Identities = 67/265 (25%), Positives = 87/265 (32%), Gaps = 45/265 (16%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 569
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 570 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 628
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 629 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 688
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 689 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 734
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGL 1972
VC+ G GE C P G+ L
Sbjct: 735 VCKDGYAGEDCGEEVPTIEGMRMHL 759
>AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 288 GRCE--NGRCVCNPGYAGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 342
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 343 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 399
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 400 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 503
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 504 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 561
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 562 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 613
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 614 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 666
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 667 CLCHVGYGGEDCGQ 680
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 256
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 257 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYAGEDCGVRSCPR 313
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 314 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 373
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 374 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 429
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 430 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 487
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 488 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 545
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 602
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 603 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 636
Score = 80.2 bits (189), Expect = 1e-13
Identities = 141/548 (25%), Positives = 192/548 (35%), Gaps = 98/548 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 198 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 255
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G +C+ C G +
Sbjct: 256 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENG-RCV-CNPGYAGED 305
Query: 337 CN-KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECR 382
C + P G+ D C CDP ++ +C S GRC C
Sbjct: 306 CGVRSCPRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW 360
Query: 383 PEFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
P + DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 361 PGYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CED 416
Query: 438 ---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYP 492
+C GY +C + C C+ G C C + YSG C C
Sbjct: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRG 474
Query: 493 TCKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYM 536
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 475 RCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRG 534
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCD 596
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 535 HGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCP 591
Query: 597 VSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGC 652
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 592 NDCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCAT 649
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN---- 708
PA C+ + R +C C + +G E C G C
Sbjct: 650 RMCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPREL 697
Query: 709 TKSGQCVC 716
++GQCVC
Sbjct: 698 CRAGQCVC 705
Score = 73.3 bits (172), Expect = 1e-11
Identities = 105/388 (27%), Positives = 139/388 (35%), Gaps = 68/388 (17%)
Query: 408 CNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDK- 465
C+L+G + CT C C+ + G +C D P + GS C+
Sbjct: 143 CSLHGVFDLSRCT-----CSCEPGWGGPTCSDPTDAEIPPSSPP---SASGSCPDDCNDQ 194
Query: 466 ---LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
+ G C C Y+G +C +P+C P +C G C V G C+C+AGF
Sbjct: 195 GRCVRGRCVCFPGYTGPSCG--------WPSC-PGDCQGRGR----C--VQGVCVCRAGF 239
Query: 523 GGPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQC 577
GP C Q C G + +CV CDP G T C S C+ +C
Sbjct: 240 SGPDCSQRSCPRGCSQRGRCEGGRCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC 295
Query: 578 DQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPAC 635
C+PG Y DC +C S C D G C C + G C T C C
Sbjct: 296 -VCNPG-YAGEDCGVRSCPRGCSQRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 636 EE--CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
+ C C P G T + P C+ R GR C D + + + G C
Sbjct: 353 VDGRCVCWP-GYTGEDCSTRTCPR----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC 404
Query: 694 NCNLAGTLNSLGACNTKSGQCVC-----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
G N G C + G+CVC G R C + G R + G C+
Sbjct: 405 ----PGDCNQRGRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNA 454
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G D G C R E RC
Sbjct: 455 GYSGE-DCGVRSCPGDCRGRGRCESGRC 481
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 295 CVCNPGYAGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 351
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 352 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 410
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 411 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 464
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 465 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 517
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 518 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 574
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 575 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 622
Score = 72.1 bits (169), Expect = 3e-11
Identities = 88/337 (26%), Positives = 115/337 (34%), Gaps = 65/337 (19%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 443 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 558
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 616
Query: 482 N--QCQAGYYNYPTCKP--CNCDTSGTEPS----ICDD--------VSGQCICKAGFGGP 525
+ C + + C+ C CD T P+ +C V G C+C G+GG
Sbjct: 617 SIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE 676
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
C G+E P + P G G+C C+ F G
Sbjct: 677 DC------------GQEEP--PASACPGGCGPRELCRAGQCVCVEGFRG----------- 711
Query: 586 KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
PDC C C D G C CK + G C
Sbjct: 712 --PDCAIQTCPGDCRGRGECHD-GSCVCKDGYAGEDC 745
Score = 64.1 bits (149), Expect = 9e-09
Identities = 68/243 (27%), Positives = 92/243 (37%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 152 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 200
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 201 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G G+ C C
Sbjct: 258 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYAGEDCGVRSC 311
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 312 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 371
Query: 2055 RCP 2057
CP
Sbjct: 372 TCP 374
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 414
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 415 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 473
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 474 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 527
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 528 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 580
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 581 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 640
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 641 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 700
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 701 -GQCVCVEGFRGPDCAIQTCP 720
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 261 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYAGEDCGVRS 310
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 311 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 362
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 363 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 417
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 418 -RCVCWPGYTGTDCGS 432
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 202 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 258
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 259 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYAGEDCGVRSCPR 313
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 314 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 369
Query: 1510 T 1510
T
Sbjct: 370 T 370
Score = 48.0 bits (109), Expect = 6e-04
Identities = 63/256 (24%), Positives = 83/256 (32%), Gaps = 50/256 (19%)
Query: 317 GRYEGGGKCLN----CQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPC----QCDPHF 367
G G G+C++ C G +C R P R +G D + VC C
Sbjct: 499 GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRS 558
Query: 368 STGNCEEES----GRCECRPEFQPPDCS--SCAYGYFDYPNCKPCTCNL-NGTEGEHCTP 420
G C GRC C + DC C + C+ C G E C+
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI 618
Query: 421 TDGLCPCKYNYAGKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY 476
CP + G+ CE +C+ GY P C C C + G C C Y
Sbjct: 619 RT--CPSNCHGRGR-CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGY 673
Query: 477 SGRTCNQ-----------------CQAGY------YNYPTCKPCNCDTSGTEPSICDDVS 513
G C Q C+AG + P C C C D
Sbjct: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHD-- 731
Query: 514 GQCICKAGFGGPRCDQ 529
G C+CK G+ G C +
Sbjct: 732 GSCVCKDGYAGEDCGE 747
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 388 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 443
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 444 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 501
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 502 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 556
Score = 42.3 bits (95), Expect = 0.032
Identities = 67/265 (25%), Positives = 87/265 (32%), Gaps = 45/265 (16%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 569
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 570 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 628
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 629 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 688
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 689 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 734
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGL 1972
VC+ G GE C P G+ L
Sbjct: 735 VCKDGYAGEDCGEEVPTIEGMRMHL 759
>AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein.
Length = 4222
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 288 GRCE--NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 342
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 343 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 399
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 400 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 503
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 504 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 561
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 562 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 613
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 614 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 666
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 667 CLCHVGYGGEDCGQ 680
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 256
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 257 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYTGEDCGVRSCPR 313
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 314 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 373
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 374 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 429
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 430 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 487
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 488 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 545
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 602
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 603 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 636
Score = 80.2 bits (189), Expect = 1e-13
Identities = 140/547 (25%), Positives = 188/547 (34%), Gaps = 96/547 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 198 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 255
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G N + E
Sbjct: 256 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
Query: 337 CNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECRP 383
C P G+ D C CDP ++ +C S GRC C P
Sbjct: 308 VRSC-PRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWP 361
Query: 384 EFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE-- 437
+ DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 362 GYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CEDG 417
Query: 438 --ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYPT 493
+C GY +C + C C+ G C C + YSG C C
Sbjct: 418 RCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRGR 475
Query: 494 CKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYMQ 537
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 476 CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 535
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDV 597
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 536 GLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCPN 592
Query: 598 SGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGCG 653
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 593 DCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCATR 650
Query: 654 SVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN----T 709
PA C+ + R +C C + +G E C G C
Sbjct: 651 MCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPRELC 698
Query: 710 KSGQCVC 716
++GQCVC
Sbjct: 699 RAGQCVC 705
Score = 73.3 bits (172), Expect = 1e-11
Identities = 105/388 (27%), Positives = 139/388 (35%), Gaps = 68/388 (17%)
Query: 408 CNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDK- 465
C+L+G + CT C C+ + G +C D P + GS C+
Sbjct: 143 CSLHGVFDLSRCT-----CSCEPGWGGPTCSDPTDAEIPPSSPP---SASGSCPDDCNDQ 194
Query: 466 ---LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
+ G C C Y+G +C +P+C P +C G C V G C+C+AGF
Sbjct: 195 GRCVRGRCVCFPGYTGPSCG--------WPSC-PGDCQGRGR----C--VQGVCVCRAGF 239
Query: 523 GGPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQC 577
GP C Q C G + +CV CDP G T C S C+ +C
Sbjct: 240 SGPDCSQRSCPRGCSQRGRCEGGRCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC 295
Query: 578 DQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPAC 635
C+PG Y DC +C S C D G C C + G C T C C
Sbjct: 296 -VCNPG-YTGEDCGVRSCPRGCSQRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 636 EE--CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
+ C C P G T + P C+ R GR C D + + + G C
Sbjct: 353 VDGRCVCWP-GYTGEDCSTRTCPR----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC 404
Query: 694 NCNLAGTLNSLGACNTKSGQCVC-----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
G N G C + G+CVC G R C + G R + G C+
Sbjct: 405 ----PGDCNQRGRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNA 454
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G D G C R E RC
Sbjct: 455 GYSGE-DCGVRSCPGDCRGRGRCESGRC 481
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 295 CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 351
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 352 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 410
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 411 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 464
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 465 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 517
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 518 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 574
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 575 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 622
Score = 72.1 bits (169), Expect = 3e-11
Identities = 88/337 (26%), Positives = 115/337 (34%), Gaps = 65/337 (19%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 443 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 558
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 616
Query: 482 N--QCQAGYYNYPTCKP--CNCDTSGTEPS----ICDD--------VSGQCICKAGFGGP 525
+ C + + C+ C CD T P+ +C V G C+C G+GG
Sbjct: 617 SIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE 676
Query: 526 RCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
C G+E P + P G G+C C+ F G
Sbjct: 677 DC------------GQEEP--PASACPGGCGPRELCRAGQCVCVEGFRG----------- 711
Query: 586 KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
PDC C C D G C CK + G C
Sbjct: 712 --PDCAIQTCPGDCRGRGECHD-GSCVCKDGYAGEDC 745
Score = 66.1 bits (154), Expect = 2e-09
Identities = 69/243 (28%), Positives = 93/243 (38%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 152 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 200
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 201 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G TG+ C C
Sbjct: 258 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYTGEDCGVRSC 311
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 312 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 371
Query: 2055 RCP 2057
CP
Sbjct: 372 TCP 374
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 414
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 415 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 473
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 474 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 527
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 528 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 580
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 581 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 640
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 641 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 700
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 701 -GQCVCVEGFRGPDCAIQTCP 720
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 261 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYTGEDCGVRS 310
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 311 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 362
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 363 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 417
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 418 -RCVCWPGYTGTDCGS 432
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 202 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 258
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 259 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYTGEDCGVRSCPR 313
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 314 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 369
Query: 1510 T 1510
T
Sbjct: 370 T 370
Score = 48.0 bits (109), Expect = 6e-04
Identities = 63/256 (24%), Positives = 83/256 (32%), Gaps = 50/256 (19%)
Query: 317 GRYEGGGKCLN----CQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPC----QCDPHF 367
G G G+C++ C G +C R P R +G D + VC C
Sbjct: 499 GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRS 558
Query: 368 STGNCEEES----GRCECRPEFQPPDCS--SCAYGYFDYPNCKPCTCNL-NGTEGEHCTP 420
G C GRC C + DC C + C+ C G E C+
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI 618
Query: 421 TDGLCPCKYNYAGKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY 476
CP + G+ CE +C+ GY P C C C + G C C Y
Sbjct: 619 RT--CPSNCHGRGR-CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGY 673
Query: 477 SGRTCNQ-----------------CQAGY------YNYPTCKPCNCDTSGTEPSICDDVS 513
G C Q C+AG + P C C C D
Sbjct: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHD-- 731
Query: 514 GQCICKAGFGGPRCDQ 529
G C+CK G+ G C +
Sbjct: 732 GSCVCKDGYAGEDCGE 747
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 388 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 443
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 444 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 501
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 502 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 556
Score = 42.3 bits (95), Expect = 0.032
Identities = 67/265 (25%), Positives = 87/265 (32%), Gaps = 45/265 (16%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 569
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 570 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 628
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 629 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 688
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 689 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 734
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGL 1972
VC+ G GE C P G+ L
Sbjct: 735 VCKDGYAGEDCGEEVPTIEGMRMHL 759
>AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB
(isoform 1)) protein.
Length = 4288
Score = 85.4 bits (202), Expect = 3e-15
Identities = 117/434 (26%), Positives = 152/434 (35%), Gaps = 66/434 (15%)
Query: 370 GNCEEESGRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLC 425
G CE +GRC C P + DC SC G CK C C+ G GE C C
Sbjct: 287 GRCE--NGRCVCNPGYAGEDCGVRSCPRGCSQRGRCKDGRCVCD-PGYTGEDCGTRS--C 341
Query: 426 PCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN 482
P G+ + +C GY +C C C+ G+C C + YSG C
Sbjct: 342 PWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDC- 398
Query: 483 QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+C P +C+ G C+D G+C+C G+ G C + GR
Sbjct: 399 -------GVRSC-PGDCNQRGR----CED--GRCVCWPGYTGTDCGSRACPRDCRGRGRC 444
Query: 542 ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSI 601
E CN +G S G C +C C PG Y DC + C
Sbjct: 445 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRC-MCWPG-YTGRDCGTRACPGDCRG 502
Query: 602 GSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPACEE--CNCDPRGVTASFAGCGSVPA 657
C D G C C F G C + C + CE+ C CD G + S P
Sbjct: 503 RGRCVD-GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD-AGYSGEDCSTRSCPG 560
Query: 658 GELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC--NCNLAGTLNSLGACNTKSG--- 712
G C+ R Q C D + + + G QC +C+ G G C G
Sbjct: 561 G----CRGRGQ---CLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD-GVCICWEGYVS 612
Query: 713 -QC---VCKQHV-GERQCDQ--CL-DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ 764
C C + G +C++ CL D Y T C D G C G
Sbjct: 613 EDCSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTCATRMCPADCRGR--GRC--VQGV 665
Query: 765 CHCHSRVEGRRCDQ 778
C CH G C Q
Sbjct: 666 CLCHVGYGGEDCGQ 679
Score = 83.8 bits (198), Expect = 1e-14
Identities = 124/455 (27%), Positives = 160/455 (35%), Gaps = 73/455 (16%)
Query: 377 GRCECRPEFQPPDCS--SCAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGLCPCKYNYA 432
GRC C P + P C SC C C C G G C+ CP +
Sbjct: 199 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRA-GFSGPDCSQRS--CPRGCSQR 255
Query: 433 GKSCE----ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQA 486
G+ CE +C+ GY +C C S C+ G C C Y+G C C
Sbjct: 256 GR-CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYAGEDCGVRSCPR 312
Query: 487 GYYNYPTCKP--CNCDTS------GTE--PSICDD----VSGQCICKAGFGGPRCDQCLS 532
G CK C CD GT P C + V G+C+C G+ G C
Sbjct: 313 GCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC 372
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQCDQCSPGYYKYPD 589
+ GR + C CD TG + C S G CN +C C PG Y D
Sbjct: 373 PRDCRGRGR-CEDGECICD-TGYSGDDCGVRSCPGDCNQRGRCEDGRC-VCWPG-YTGTD 428
Query: 590 CLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACE--ECNCDPRGV 645
C S C C +NG+C C + + G C +C CE C C P G
Sbjct: 429 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GY 486
Query: 646 TASFAGCGSVPAGELCQCKDR-VQGR-ICN------DCKPLYWNLQEYNPFGCEQ----C 693
T G + P C+ + R V GR +CN DC CE C
Sbjct: 487 TGRDCGTRACPGD--CRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 544
Query: 694 NCNLAG----TLNSLGACNTK----SGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGC 743
+ +G T + G C + G+CVC+ C QC + + V
Sbjct: 545 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND---CSQHGVCQD 601
Query: 744 TECDCDIGGSIDNNCDKTT--GQCHCHSRVEGRRC 776
C C G + +C T CH R E RC
Sbjct: 602 GVCIC-WEGYVSEDCSIRTCPSNCHGRGRCEEGRC 635
Score = 80.2 bits (189), Expect = 1e-13
Identities = 141/548 (25%), Positives = 192/548 (35%), Gaps = 98/548 (17%)
Query: 227 IGGRCMC-NGHAD-TCE----PADPAGNLNIL--VCRCQHNTCGPQCNK--CCSGFEQKK 276
+ GRC+C G+ +C P D G + VC C+ GP C++ C G Q
Sbjct: 197 VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ-- 254
Query: 277 WRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGIN 336
R R C+P +T + D + GR E G +C+ C G +
Sbjct: 255 -RGRCEGGRCVCDP----GYTGD---DCGMRSCPRGCSQRGRCENG-RCV-CNPGYAGED 304
Query: 337 CN-KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEES-------------GRCECR 382
C + P G+ D C CDP ++ +C S GRC C
Sbjct: 305 CGVRSCPRGCSQRGRCKDGR-----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW 359
Query: 383 PEFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE- 437
P + DCS +C C+ C C+ G G+ C CP N G+ CE
Sbjct: 360 PGYTGEDCSTRTCPRDCRGRGRCEDGECICD-TGYSGDDCGVRS--CPGDCNQRGR-CED 415
Query: 438 ---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC--NQCQAGYYNYP 492
+C GY +C + C C+ G C C + YSG C C
Sbjct: 416 GRCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRG 473
Query: 493 TCKP--CNC------DTSGTE--PSICDD----VSGQCICKAGFGGPRCD--QCLSGYYM 536
C+ C C GT P C V G+C+C GF G C +C
Sbjct: 474 RCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRG 533
Query: 537 QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCD 596
L + CV C+ +G ++ S G C +C C G Y DC C
Sbjct: 534 HGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQCLDGRC-VCEDG-YSGEDCGVRQCP 590
Query: 597 VSGSIGSTCDDNGLCHCKSNFDGAKCD--TCREQFYNYPACEE--CNCDPRGVTASFAGC 652
S C D G+C C + C TC + CEE C CDP G T
Sbjct: 591 NDCSQHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP-GYTGPTCAT 648
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN---- 708
PA C+ + R +C C + +G E C G C
Sbjct: 649 RMCPAD--CRGRGRCVQGVCL-C---------HVGYGGEDCGQEEPPASACPGGCGPREL 696
Query: 709 TKSGQCVC 716
++GQCVC
Sbjct: 697 CRAGQCVC 704
Score = 77.8 bits (183), Expect = 7e-13
Identities = 92/332 (27%), Positives = 118/332 (35%), Gaps = 47/332 (14%)
Query: 317 GRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPC----QCDPHFSTGNC 372
GR E G N ++ E C P R G+ +C P C G+C
Sbjct: 442 GRCENGVCVCNAGYSGEDCGVRSC-PGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 500
Query: 373 EEES----GRCECRPEFQPPDCSS--CAYGYFDYPNCKP--CTCNLNGTEGEHCTPTDGL 424
GRC C P F DC S C + C+ C C+ G GE C+
Sbjct: 501 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDA-GYSGEDCSTRS-- 557
Query: 425 CPCKYNYAGKSCE---ICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTC 481
CP G+ + +CEDGY +C +C S VC G C C Y C
Sbjct: 558 CPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDC 615
Query: 482 NQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGR 541
+ TC P NC G C++ G+C+C G+ GP C + + GR
Sbjct: 616 S--------IRTC-PSNCHGRGR----CEE--GRCLCDPGYTGPTCATRMCPADCRGRGR 660
Query: 542 ERQCVPCNC------DPTGSTSTSCSA-DGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q V C C + G SA G C QC C G+ + PDC
Sbjct: 661 CVQGV-CLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQC-VCVEGF-RGPDCAIQT 717
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCR 626
C C D G C CK + G C R
Sbjct: 718 CPGDCRGRGECHD-GSCVCKDGYAGEDCGEAR 748
Score = 73.3 bits (172), Expect = 1e-11
Identities = 105/388 (27%), Positives = 139/388 (35%), Gaps = 68/388 (17%)
Query: 408 CNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDK- 465
C+L+G + CT C C+ + G +C D P + GS C+
Sbjct: 142 CSLHGVFDLSRCT-----CSCEPGWGGPTCSDPTDAEIPPSSPP---SASGSCPDDCNDQ 193
Query: 466 ---LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGF 522
+ G C C Y+G +C +P+C P +C G C V G C+C+AGF
Sbjct: 194 GRCVRGRCVCFPGYTGPSCG--------WPSC-PGDCQGRGR----C--VQGVCVCRAGF 238
Query: 523 GGPRCDQ--CLSGYYMQVLGRERQCVPCNCDPTGSTSTSC---SADGKCNCLTNFGGAQC 577
GP C Q C G + +CV CDP G T C S C+ +C
Sbjct: 239 SGPDCSQRSCPRGCSQRGRCEGGRCV---CDP-GYTGDDCGMRSCPRGCSQRGRCENGRC 294
Query: 578 DQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT--CREQFYNYPAC 635
C+PG Y DC +C S C D G C C + G C T C C
Sbjct: 295 -VCNPG-YAGEDCGVRSCPRGCSQRGRCKD-GRCVCDPGYTGEDCGTRSCPWDCGEGGRC 351
Query: 636 EE--CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
+ C C P G T + P C+ R GR C D + + + G C
Sbjct: 352 VDGRCVCWP-GYTGEDCSTRTCPR----DCRGR--GR-CEDGECICDTGYSGDDCGVRSC 403
Query: 694 NCNLAGTLNSLGACNTKSGQCVC-----KQHVGERQCDQCLDGFYRLQTNDVFGCTECDC 748
G N G C + G+CVC G R C + G R + G C+
Sbjct: 404 ----PGDCNQRGRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN----GVCVCNA 453
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G D G C R E RC
Sbjct: 454 GYSGE-DCGVRSCPGDCRGRGRCESGRC 480
Score = 72.5 bits (170), Expect = 3e-11
Identities = 100/352 (28%), Positives = 128/352 (36%), Gaps = 54/352 (15%)
Query: 1736 CQCPRAYRGLSC--EQCAEG---HYRLPSGFCVPCQCNGHSDQCDVNTGIC-LNCADN-- 1787
C C Y G C C G R G CV C G++ + D T C +C +
Sbjct: 294 CVCNPGYAGEDCGVRSCPRGCSQRGRCKDGRCV-CD-PGYTGE-DCGTRSCPWDCGEGGR 350
Query: 1788 TIGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSE 1834
+ C C GY G+ +T PRDC C C Y ++ + SC D ++
Sbjct: 351 CVDGRC-VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQ 409
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
G C C PGY G C G P D C C+ + +D G
Sbjct: 410 RGRCEDGRCVCWPGYTGTDC-----GSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-VR 463
Query: 1893 SINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPG 1952
S GDC + C +C PG+ G ++ AC D G C G CVC PG
Sbjct: 464 SCPGDC-RGRGRCESGRC-MCWPGYTGRDCGTR---ACPGDCRGRGRC--VDGRCVCNPG 516
Query: 1953 VIGEKCD--RCAPDHWGLNTGL---GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
GE C RC D G GL G C+ G + E G CR +C
Sbjct: 517 FTGEDCGSRRCPGDCRG--HGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRC- 573
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCD--RCP 2057
C G Y+ + C C S +C G C C G + E C CP
Sbjct: 574 VCEDG---YSGEDCGVRQCPNDCSQHGVCQ-DGVCICWEGYVSEDCSIRTCP 621
Score = 64.1 bits (149), Expect = 9e-09
Identities = 68/243 (27%), Positives = 92/243 (37%), Gaps = 42/243 (17%)
Query: 1837 SLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
S +C+C+PG+GG C IP + C P +C+ D G C + G
Sbjct: 151 SRCTCSCEPGWGGPTCSDPTDA--EIPPSSPPSASGSC-PDDCN------DQGRC--VRG 199
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT--ACICDE-FGMADCD--STTGTCVCRP 1951
C+ C G +C P GD C C+C F DC S C R
Sbjct: 200 RCV-CFPGYTGPSCGW--PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRG 256
Query: 1952 GVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD--QC 2009
G +C C P + G + G+ P C S+ +C +NG+C C G G+ C C
Sbjct: 257 RCEGGRC-VCDPGYTGDDCGMRSCPRGC---SQRGRC--ENGRCVCNPGYAGEDCGVRSC 310
Query: 2010 AAGFWNYTKDGCDHCNCNTGY--------SVGFMCN-----ATGQCECLPGVIGEKCD-- 2054
G + C C+ GY S + C G+C C PG GE C
Sbjct: 311 PRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 370
Query: 2055 RCP 2057
CP
Sbjct: 371 TCP 373
Score = 56.4 bits (130), Expect = 2e-06
Identities = 100/381 (26%), Positives = 126/381 (33%), Gaps = 76/381 (19%)
Query: 1736 CQCPRAYRGLSCEQ--C---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C C G R G C+ C D C V + G C N
Sbjct: 356 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI-CDTGYSGDDCGVRSCPGDC-NQRGRC 413
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SC--DLSEN 1835
C C GY G + PRDC +C C Y + + SC D
Sbjct: 414 EDGRC-VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR 472
Query: 1836 GSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
G S C C PGY G C G P D C C+ +D GS
Sbjct: 473 GRCESGRCMCWPGYTGRDC-----GTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS-RR 526
Query: 1894 INGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGV 1953
GDC + C +C G+ G+ +++C C G C G CVC G
Sbjct: 527 CPGDC-RGHGLCEDGVC-VCDAGYSGEDCSTRSCPGG-CR--GRGQC--LDGRCVCEDGY 579
Query: 1954 IGEKCD--RCAPD---HWGLNTGL-----GCTPCNCGIASESTQCDD----DNGQCRCAK 1999
GE C +C D H G+ G +C I + + C + G+C C
Sbjct: 580 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 639
Query: 2000 GVTGKQC------------DQCAAGFW----NYTKDGCDH-----CNCNTGYSVGFMCNA 2038
G TG C +C G Y + C C G +C A
Sbjct: 640 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 699
Query: 2039 TGQCECLPGVIGEKC--DRCP 2057
GQC C+ G G C CP
Sbjct: 700 -GQCVCVEGFRGPDCAIQTCP 719
Score = 54.4 bits (125), Expect = 7e-06
Identities = 64/196 (32%), Positives = 78/196 (39%), Gaps = 35/196 (17%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCD-RC 1414
GG+C C P G C G +C P C C+ NG C+C GE+C R
Sbjct: 260 GGRCVCDPGYTGDDC--------GMRSC-PRGCSQRGRCE-NGRCVCNPGYAGEDCGVRS 309
Query: 1415 KPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH---CVPG 1468
P + QRG C D C C+P G G C S C E GR D C PG
Sbjct: 310 CPRGCS---QRGRCKDGRCVCDP-GYTGE--DCGTRSCPWDCGEG--GRCVDGRCVCWPG 361
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD--TCKEEYFNLQDDNPDGC 1526
Y DC TC R C+ +C C T G C +C + N + DG
Sbjct: 362 -YTGEDCSTRTCPRDCRGRGRCED--GECICDTGYSGDDCGVRSCPGD-CNQRGRCEDG- 416
Query: 1527 TKCFCF-GKT-TRCSS 1540
+C C+ G T T C S
Sbjct: 417 -RCVCWPGYTGTDCGS 431
Score = 48.4 bits (110), Expect = 5e-04
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECN--TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP----STAI 1393
C+C F G T C + G C + + C CR G+ G P+C CP
Sbjct: 201 CVC-FPGYTGPSCGWPSCPGDCQGRGRCVQGVC-VCRAGFSG-PDCSQRSCPRGCSQRGR 257
Query: 1394 CDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRG-CDD--CNCNPLGVVGNQLQCEADSG 1449
C+ G C+C G++C R P + QRG C++ C CNP G G +
Sbjct: 258 CE-GGRCVCDPGYTGDDCGMRSCPRGCS---QRGRCENGRCVCNP-GYAGEDCGVRSCPR 312
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ R + C C PG Y DC +C C +C C G+ C
Sbjct: 313 GCSQRGRCKDGRC-VCDPG-YTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCS 368
Query: 1510 T 1510
T
Sbjct: 369 T 369
Score = 47.2 bits (107), Expect = 0.001
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS----ACRTGYYGFP-NCRPC--HCPSTA 1392
C+CD G + +C CP N GR C C GY G R C C
Sbjct: 387 CICD-TGYSGDDCGV--RSCPGDCNQRGR-CEDGRCVCWPGYTGTDCGSRACPRDCRGRG 442
Query: 1393 ICDDNGMCICPKNVEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKC 1451
C+ NG+C+C GE+C R P + C C P G G A G C
Sbjct: 443 RCE-NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWP-GYTGRDCGTRACPGDC 500
Query: 1452 ACREN-VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
R V GR C PG + DC C + +C+ C C G+ C T
Sbjct: 501 RGRGRCVDGRCV--CNPG-FTGEDCGSRRCPGDCRGHGLCEDGV--CVCDAGYSGEDCST 555
Score = 43.6 bits (98), Expect = 0.014
Identities = 91/344 (26%), Positives = 114/344 (33%), Gaps = 69/344 (20%)
Query: 1736 CQCPRAYRGLSCEQCA-----EGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C Y G C A G R +G CV C + C V + G C
Sbjct: 418 CVCWPGYTGTDCGSRACPRDCRGRGRCENGVCV-CNAGYSGEDCGVRSCPGDCRGRGRCE 476
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNF-ALSC--DLSEN 1835
G C C GY G T P DC C C + + + C D +
Sbjct: 477 SG-RC-MCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGH 534
Query: 1836 GSLIS--CNCQPGYGGARCEY--CAAGYYGIPEDTDL-------HTGDYCK----PCNCS 1880
G C C GY G C C G G + D ++G+ C P +CS
Sbjct: 535 GLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCS 594
Query: 1881 GNINPQDPGSCDSING----DCL--KCVNNTAGAA-CN----LCAPGFYGDAIFSKNCTA 1929
+ QD G C G DC C +N G C LC PG+ G ++ C A
Sbjct: 595 QHGVCQD-GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPA 653
Query: 1930 CICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
D G C G C+C G GE C + P P CG E +
Sbjct: 654 ---DCRGRGRC--VQGVCLCHVGYGGEDCGQEEPP-------ASACPGGCG-PRELCRA- 699
Query: 1990 DDNGQCRCAKGVTGKQC--DQCAAGFWNYTKDGCDHCNCNTGYS 2031
GQC C +G G C C + C C GY+
Sbjct: 700 ---GQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYA 740
Score = 40.7 bits (91), Expect = 0.097
Identities = 64/251 (25%), Positives = 83/251 (33%), Gaps = 45/251 (17%)
Query: 1736 CQCPRAYRGLSC--EQC---AEGHYRLPSGFCVPCQCNGHSDQCDVNT--GICLNCADNT 1788
C C + G C +C GH G CV C + C + G C
Sbjct: 511 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCV-CDAGYSGEDCSTRSCPGGCRG-RGQC 568
Query: 1789 IGDHCEFCMSGYHGD--ATVGTPRDCL--------ICACPMPYPSNNFAL-SCDLSENG- 1836
+ C C GY G+ P DC +C C Y S + ++ +C + +G
Sbjct: 569 LDGRC-VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGR 627
Query: 1837 ---SLISCNCQPGYGGARC--EYCAAGYYGIPEDTD----LHTGDYCKPCNCSGNINPQD 1887
C C PGY G C C A G H G + C
Sbjct: 628 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASAC 687
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
PG C G C AG +C GF G + C D G +C G+C
Sbjct: 688 PGGC----GPRELC---RAGQC--VCVEGFRGPDCAIQTCPG---DCRGRGECHD--GSC 733
Query: 1948 VCRPGVIGEKC 1958
VC+ G GE C
Sbjct: 734 VCKDGYAGEDC 744
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 85.4 bits (202), Expect = 3e-15
Identities = 129/527 (24%), Positives = 183/527 (34%), Gaps = 87/527 (16%)
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGR----YEGGGKCLNCQHNTEGINCNK 339
DR + C C + + T ++DE + NG G +C C EG C++
Sbjct: 486 DRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGFEGTLCDR 544
Query: 340 ----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAY 395
C P +G+ D + C C P ++ CE + C +P C
Sbjct: 545 NVDDCSPDPCH-HGRCVDGI-ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVD 602
Query: 396 GYFDYPNCKPCTCNLNGTEGEHCTPTDGLC---PCKYNYAGKSCE----ICEDGYYSPEC 448
Y C C +GT G +C C PC + +C+ G+ P C
Sbjct: 603 KYL-------CRCP-SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLC 654
Query: 449 KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN--CDTSGTEP 506
N E N S C + +C +G C C G P C P + C
Sbjct: 655 -NVEINECASSP--CGE---GGSCVDGENGFRC-LCPPGSLP-PLCLPPSHPCAHEPCSH 706
Query: 507 SICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
IC D G +C+C+ G+ GPRC Q L+ R+ C P + T CS+DG
Sbjct: 707 GICYDAPGGFRCVCEPGWSGPRCSQSLA--------RD----ACESQPCRAGGT-CSSDG 753
Query: 565 ---KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAK 621
C C G QC+ SP C C+ G S +C C + G +
Sbjct: 754 MGFHCTCPPGVQGRQCELLSP-------CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPR 806
Query: 622 CDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC----NDC-- 675
C ++ PA C P G+ + AG S C C G C NDC
Sbjct: 807 CQQDVDECAG-PA----PCGPHGICTNLAGSFS------CTCHGGYTGPSCDQDINDCDP 855
Query: 676 KPLYWNLQEYNPFGCEQCNC--NLAG--TLNSLGAC-NTKSGQCVCKQHVGERQCDQCLD 730
P + G C+C AG + C + G C HV C C
Sbjct: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTC-TCPP 914
Query: 731 GFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G+ D+ C+ C GG+ + + + C C G C
Sbjct: 915 GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFS--CLCRPGYTGAHC 959
Score = 83.0 bits (196), Expect = 2e-14
Identities = 153/585 (26%), Positives = 203/585 (34%), Gaps = 99/585 (16%)
Query: 233 CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWD-RFSC 288
C G C+ + AG CRC GP C+ C S R S D RF C
Sbjct: 87 CAGRG-VCQSSVVAGTARFS-CRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLC 144
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINCNK- 339
C C D +DE R + GG CLN C G C
Sbjct: 145 S-CPPGYQGRSCRSD--VDECR----VGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
Query: 340 ---CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYG 396
C P+ R G D+ C C P F NCE C P + + +C G
Sbjct: 198 AVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDG 254
Query: 397 YFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN--YAGKSCEICEDGYYSPECKNCECN 454
Y NC+ C T G+ CT C + N + G +C G+ +C C
Sbjct: 255 VNTY-NCQ---CPPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGH------SCVC- 302
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY-NYPTCKP---CNCDTSGT-----E 505
G C + DC + G TC+ A +Y P K C+ D + E
Sbjct: 303 VNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHE 362
Query: 506 PSICD--DVSGQ--CICKAGFGGPRCDQ----CLSGYY-MQVLGR---ERQCVPCNCDPT 553
+ICD V+G+ C C GF G CDQ C G + LGR + C C
Sbjct: 363 DAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG-R 421
Query: 554 GSTSTSCSAD------GKC----NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
G T C D G C CL G C C G+ C D+ S
Sbjct: 422 GYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC-ICMAGF----TGTYCEVDIDECQSS 476
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGEL 660
C + G+ CK +G C TC F +EC P + A C P G
Sbjct: 477 PCVNGGV--CKDRVNGFSC-TCPSGFSGSTCQLDVDECASTP---CRNGAKCVDQPDGYE 530
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C+C + +G +C+ N+ + +P C C + G + AC C+ V
Sbjct: 531 CRCAEGFEGTLCDR------NVDDCSPDPCHHGRC-VDGIASFSCACAPGYTGTRCESQV 583
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
E + C G L D + C C G+ NC+ C
Sbjct: 584 DECRSQPCRHGGKCLDLVDKYLC-RCP---SGTTGVNCEVNIDDC 624
Score = 68.9 bits (161), Expect = 3e-10
Identities = 93/370 (25%), Positives = 127/370 (34%), Gaps = 60/370 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVP------CQC---------NGHSDQCDV 1776
+C C + G +CE + GH L G CV CQC D+C +
Sbjct: 221 DCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQL 280
Query: 1777 NTGICLNCAD--NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN----NFALSC 1830
C N NT+G H C++G+ G++ DC C + +F +C
Sbjct: 281 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 340
Query: 1831 DLSENGSLI----SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP--CNCSGNIN 1884
+ + G L +C P + A C+ I TG C CS N
Sbjct: 341 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 400
Query: 1885 P-QDPGSCDSINGDCL-KCVNNTAGAAC----NLCAPG---FYGDAIFSKNCTACIC-DE 1934
P + G C + G L +C G C N C G + CIC
Sbjct: 401 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAG 460
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKC-DR-------CAPDHWGLNTGLGCTPCNCGIASEST 1986
F C+ C P V G C DR C G L C
Sbjct: 461 FTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGA 520
Query: 1987 QCDD--DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCEC 2044
+C D D +CRCA+G G CD+ + + D C H C G A+ C C
Sbjct: 521 KCVDQPDGYECRCAEGFEGTLCDR---NVDDCSPDPCHHGRCVDGI-------ASFSCAC 570
Query: 2045 LPGVIGEKCD 2054
PG G +C+
Sbjct: 571 APGYTGTRCE 580
Score = 68.9 bits (161), Expect = 3e-10
Identities = 92/342 (26%), Positives = 122/342 (35%), Gaps = 61/342 (17%)
Query: 1733 VEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ECQ G C+ G PSGF C D+C C N C D
Sbjct: 470 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFS-GSTCQLDVDECASTP--CRNGAKCVDQP 526
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C G+ G DC P P ++ ++ SC C PGY
Sbjct: 527 DGYECR-CAEGFEGTLCDRNVDDC------SPDPCHHGRCVDGIAS----FSCACAPGYT 575
Query: 1849 GARCEYCAAGYYGIP-----EDTDLHTGDYCK-PCNCSG---NINPQDPGSCDSINGDCL 1899
G RCE P + DL C+ P +G +N D S G C
Sbjct: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
+N C +C PGF G + C + C E G C+C PG +
Sbjct: 636 DGINR---YDC-VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPL 691
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN 2015
C P H PC+ GI C D G +C C G +G +C Q A
Sbjct: 692 C--LPPSH-----PCAHEPCSHGI------CYDAPGGFRCVCEPGWSGPRCSQSLA---- 734
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCD 2054
+D C+ C G + C++ G C C PGV G +C+
Sbjct: 735 --RDACESQPCRAGGT----CSSDGMGFHCTCPPGVQGRQCE 770
Score = 68.9 bits (161), Expect = 3e-10
Identities = 145/576 (25%), Positives = 195/576 (33%), Gaps = 94/576 (16%)
Query: 236 HADTCEPADPAGNLNILVCRCQHNTCGPQC----NKCCSGFEQKKWRISQNW-DRFSCEP 290
H CE A G L VC C GP+C ++C I N FSC
Sbjct: 782 HGGRCESAP--GQLP--VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC-- 835
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
CH T + D +I++ D N GG +CQ +C+ C P + P
Sbjct: 836 -TCHGGYTGPSCDQDIND----CDPNPCLNGG----SCQDGVGSFSCS-CLPGFAGPRCA 885
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEE--SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
R ++D C C P G C + S C C P + C D P+C P +C
Sbjct: 886 R--DVDECLSNPCGP----GTCTDHVASFTCTCPPGYGGFHCEQ------DLPDCSPSSC 933
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVCDK 465
GT + C C+ Y G C+ D S C + C G +
Sbjct: 934 FNGGTCVDGVNSFS--CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
TG C++ + CQ G T C C G +CD S C A G
Sbjct: 992 FTGP-QCQTLVDWCSRQPCQNGGRCVQTGAYCLCPP-GWSGRLCDIRSLPCREAAAQIGV 1049
Query: 526 RCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPG 583
R +Q C +G CV C P G T + C + C G C G
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHYCV---C-PEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1105
Query: 584 YYKYPDCLSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
Y C C + G G C+D+ C + G C ++ C+C P
Sbjct: 1106 YM-------CEC-LPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL-------CSCPP 1150
Query: 643 R--GVTASFA--GCGSVP---AGELC----QCKDRVQGRICNDCKPLYWNLQ-EYNPFGC 690
GV CG P +G C C D V G C C P Y L+ E + C
Sbjct: 1151 GTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT-CPPGYTGLRCEADINEC 1209
Query: 691 EQCNCNLAGTLNSLGACNTKSG-QCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD 749
C+ A T + L + G +C+C +C L C C
Sbjct: 1210 RSGACHAAHTRDCLQ--DPGGGFRCLCHAGFSGPRCQTVLSP-----------CESQPCQ 1256
Query: 750 IGGSIDNNCDKTTG---QCHCHSRVEGRRCDQPIRA 782
GG + G CHC G RC++ R+
Sbjct: 1257 HGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARS 1292
Score = 68.5 bits (160), Expect = 4e-10
Identities = 107/440 (24%), Positives = 138/440 (31%), Gaps = 61/440 (13%)
Query: 360 PCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEH 417
PC P G C G CEC P + +C D C C G+ +
Sbjct: 1087 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED------DVDECASQPCQHGGSCIDL 1140
Query: 418 CTPTDGLCPCKYNYAGKSCEICED--GYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
LC C G CEI ED G P C G+ C L G CTC
Sbjct: 1141 VARY--LCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT----CVDLVGGFRCTCP 1194
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLS 532
Y+G C + C+ C + T + D G +C+C AGF GPRC LS
Sbjct: 1195 PGYTGLRCEA------DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLS 1248
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Q QC P G T T C+C F G +C++ + C
Sbjct: 1249 PCESQPCQHGGQCRPSPGPGGGLTFT-------CHCAQPFWGPRCERVA------RSCRE 1295
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC 652
C V T C C G +CR + P +C C
Sbjct: 1296 LQCPVGVPCQQT-PRGPRCACPPGLSG---PSCRSFPGSPPGASNASC-AAAPCLHGGSC 1350
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA-------GTLNSLG 705
P +C QG C+ + C + C NS G
Sbjct: 1351 RPAPLAPFFRCA-CAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1409
Query: 706 ACNTKSGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGCTEC-----DCDIGGSIDNNC 758
C G C RQC+ QC F + + C DC GG + C
Sbjct: 1410 -CGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGR-ERTC 1467
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
+ + +C RCDQ
Sbjct: 1468 NPVY-EKYCADHFADGRCDQ 1486
Score = 68.1 bits (159), Expect = 6e-10
Identities = 97/377 (25%), Positives = 133/377 (35%), Gaps = 69/377 (18%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCV------PCQCNG-------HSDQCDVNT 1778
C CP+ ++G C+Q CA P G C C C+G D D +
Sbjct: 796 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
Query: 1779 GICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
CLN C D C C+ G+ G +CL C P +C +++
Sbjct: 856 NPCLNGGSCQDGVGSFSCS-CLPGFAGPRCARDVDECLSNPCG---PG-----TC--TDH 904
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPE--DTDLHTGDYCKP--CNCSGNINPQDPGS- 1890
+ +C C PGYGG CE +P+ + G C + S P G+
Sbjct: 905 VASFTCTCPPGYGGFHCE------QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAH 958
Query: 1891 CDSINGDCLK--CVNNTAGAACNLCAPGFYGDAIFSKNCTAC--ICDEFGMADCDS---- 1942
C CL C++ G C+ PGF + S C + D C +
Sbjct: 959 CQHEADPCLSRPCLH---GGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC 1015
Query: 1943 --TTGTCVCRPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAK 1999
T C+C PG G CD R P +G A +D + C C +
Sbjct: 1016 VQTGAYCLCPPGWSGRLCDIRSLPCREAA-AQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1074
Query: 2000 GVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
G TG C+Q C H GY G+M CECLPG G+ C+ +
Sbjct: 1075 GRTGSHCEQEVD---PCLAQPCQHGGTCRGYMGGYM------CECLPGYNGDNCEDDVDE 1125
Query: 2060 WVLIPQEGCLECDSCTD 2076
P C SC D
Sbjct: 1126 CASQP---CQHGGSCID 1139
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/371 (25%), Positives = 131/371 (35%), Gaps = 64/371 (17%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC+C + G C++ + C P C+ H D CA G CE
Sbjct: 530 ECRCAEGFEGTLCDRNVDD--------CSPDPCH-HGRCVDGIASFSCACAPGYTGTRCE 580
Query: 1795 F----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCD----------LSENG-S 1837
C S HG + D +C CP N ++ D + +G +
Sbjct: 581 SQVDECRSQPCRHGGKCLDLV-DKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGIN 639
Query: 1838 LISCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPCNCS-GNINPQD-PGSC 1891
C CQPG+ G C CA+ G E G+ C C G++ P P S
Sbjct: 640 RYDCVCQPGFTGPLCNVEINECASSPCG--EGGSCVDGENGFRCLCPPGSLPPLCLPPSH 697
Query: 1892 DSINGDCLK--CVNNTAGAACNLCAPGFYG----DAIFSKNCTACICDEFGMADCDSTTG 1945
+ C C + G C +C PG+ G ++ C + C G D
Sbjct: 698 PCAHEPCSHGICYDAPGGFRC-VCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF 756
Query: 1946 TCVCRPGVIGEKCDRCAP------DHWG-LNTGLGCTP-CNCGIASESTQCDDDNGQCRC 1997
C C PGV G +C+ +P +H G + G P C+C + +C D +C
Sbjct: 757 HCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDEC-A 815
Query: 1998 AKGVTGKQ--CDQCAAGF-----WNYTKDGCDH----CNCNTGYSVGFMCNATG--QCEC 2044
G C A F YT CD C+ N + G + G C C
Sbjct: 816 GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC 875
Query: 2045 LPGVIGEKCDR 2055
LPG G +C R
Sbjct: 876 LPGFAGPRCAR 886
Score = 58.4 bits (135), Expect = 5e-07
Identities = 92/360 (25%), Positives = 126/360 (35%), Gaps = 77/360 (21%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG--ICLNCADNTIGDHC 1793
C+CPR +RG C LP C+ C H +C V +C G C
Sbjct: 106 CRCPRGFRGPDCS--------LPDP-CLSSPC-AHGARCSVGPDGRFLCSCPPGYQGRSC 155
Query: 1794 ----EFCMSG---YHGDATVGTPRDCLICACPMPYPS---NNFALSCDLS---------E 1834
+ C G HG + TP C CP Y N A+ C S +
Sbjct: 156 RSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQ 214
Query: 1835 NGSL-ISCNCQPGYGGARCEY---CAAGYYGIPEDT---DLHTGDYCKPCNCSGNINPQD 1887
+G L C C PG+ G CE G+ + T ++T + P +G +D
Sbjct: 215 SGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTED 274
Query: 1888 PGSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDS 1942
C C C N G +C +C G+ G++ +C +C F A C
Sbjct: 275 VDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCSQNIDDCATAVC--FHGATCHD 331
Query: 1943 TTGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CR 1996
+ C C G G C L+ PC+ E CD + NG+ C
Sbjct: 332 RVASFYCACPMGKTGLLCH--------LDDACVSNPCH-----EDAICDTNPVNGRAICT 378
Query: 1997 CAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCD 2054
C G TG CDQ D C N +G N G C+C G G +C+
Sbjct: 379 CPPGFTGGACDQ--------DVDECS-IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE 429
Score = 52.0 bits (119), Expect = 4e-05
Identities = 97/376 (25%), Positives = 131/376 (34%), Gaps = 66/376 (17%)
Query: 1736 CQCPRAYRGLSCEQ----CAE------GHYRLPSGFCVPCQC-NGHSDQ-CDVNTGIC-- 1781
CQCP Y G CE CA G R C C G Q C+VN C
Sbjct: 183 CQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPG 242
Query: 1782 ---LN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
LN C D +C+ C + G +C + P +N +C +
Sbjct: 243 HRCLNGGTCVDGVNTYNCQ-CPPEWTGQFCTEDVDECQL----QPNACHNGG-TCFNTLG 296
Query: 1836 GSLISCNCQPGYGGARCEY----CAAG--YYGIPEDTDLHTGDYCK-PCNCSGNINPQDP 1888
G SC C G+ G C CA ++G D YC P +G + D
Sbjct: 297 GH--SCVCVNGWTGESCSQNIDDCATAVCFHGATCH-DRVASFYCACPMGKTGLLCHLDD 353
Query: 1889 GSCDS-INGDCLKCVNNTAGAACNLCAPGFYGDAIFSK--NCT--ACICDEFGMADCDST 1943
+ + D + N G A C PGF G A C+ A C+ G C +T
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGR--CVNT 411
Query: 1944 TGT--CVCRPGVIGEKCDR---------CAPDHWGLNTGLGCTPCNCGIASESTQCDDDN 1992
G+ C C G G +C+ C L+ +G C C T C+ D
Sbjct: 412 QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDR-IGQFTCICMAGFTGTYCEVDI 470
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGE 2051
+C+ + V G C GF C C +G+S G C +C P G
Sbjct: 471 DECQSSPCVNGGVCKDRVNGF---------SCTCPSGFS-GSTCQLDVDECASTPCRNGA 520
Query: 2052 KCDRCPERWVLIPQEG 2067
KC P+ + EG
Sbjct: 521 KCVDQPDGYECRCAEG 536
Score = 48.8 bits (111), Expect = 4e-04
Identities = 89/346 (25%), Positives = 116/346 (33%), Gaps = 63/346 (18%)
Query: 1736 CQCPRAYRGLSCE----QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP + G C+ C E ++ CQ G D ++ C+ C + G
Sbjct: 1022 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED-SSHYCV-CPEGRTGS 1079
Query: 1792 HCEF----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
HCE C++ HG G + C C Y +N C+ + C QP
Sbjct: 1080 HCEQEVDPCLAQPCQHGGTCRGYMGGYM-CECLPGYNGDN----CE----DDVDECASQP 1130
Query: 1846 GYGGARCEYCAAGYY-GIPEDTDLHTGDYCK--PCNCSGNINPQDPGSCDSINGDCLKCV 1902
G C A Y P T G C+ +C G P D G NG C+ V
Sbjct: 1131 CQHGGSCIDLVARYLCSCPPGT---LGVLCEINEDDC-GPGPPLDSGPRCLHNGTCVDLV 1186
Query: 1903 NNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTG---TCVCRPGVIGEK 1957
G C C PG+ G + C + C DC G C+C G G +
Sbjct: 1187 G---GFRCT-CPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPR 1242
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGK---QCDQCAAGFW 2014
C +PC ES C GQCR + G G C CA FW
Sbjct: 1243 CQTVL------------SPC------ESQPCQH-GGQCRPSPGPGGGLTFTC-HCAQPFW 1282
Query: 2015 NYTKDGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCP 2057
+ VG C T + C C PG+ G C P
Sbjct: 1283 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFP 1328
Score = 48.0 bits (109), Expect = 6e-04
Identities = 58/249 (23%), Positives = 87/249 (34%), Gaps = 27/249 (10%)
Query: 1840 SCNCQPGYGGARCEY---CAAGYY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
+C C PG+ G RC+ C +G G+ + + + G C C D D
Sbjct: 64 ACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVV-AGTARFSCRCPRGFRGPDCSLPDP 122
Query: 1894 -INGDCL---KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
++ C +C G C PG+ G ++C + + DE + + GTC+
Sbjct: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQG-----RSCRSDV-DECRVGEPCRHGGTCLN 176
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
PG +C N + C P C Q D C C G G+ C+
Sbjct: 177 TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE-- 234
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCL 2069
D C C G + N T C+C P G+ C + L P C
Sbjct: 235 ------VNVDDCPGHRCLNGGTCVDGVN-TYNCQCPPEWTGQFCTEDVDECQLQP-NACH 286
Query: 2070 ECDSCTDAL 2078
+C + L
Sbjct: 287 NGGTCFNTL 295
Score = 46.8 bits (106), Expect = 0.001
Identities = 88/350 (25%), Positives = 112/350 (32%), Gaps = 65/350 (18%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEF---CMSG-------YHGDATVGTPRDCL 1813
PC G Q CL C +G+ C+ C SG GT R
Sbjct: 48 PCANGGRCTQLPSREAACL-CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSC 106
Query: 1814 ICA-------CPMPYPSNNFALS----CDLSENGSLISCNCQPGYGGARC----EYCAAG 1858
C C +P P + + C + +G + C+C PGY G C + C G
Sbjct: 107 RCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFL-CSCPPGYQGRSCRSDVDECRVG 165
Query: 1859 YYGIPEDTDLHT-GDYCKPCN-------CSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
T L+T G + C C P P C + G C + + T AC
Sbjct: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRN-GGTCRQSGDLTYDCAC 224
Query: 1911 NLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC----DRCA-- 1962
PGF G + +C C G T C C P G+ C D C
Sbjct: 225 ---LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 281
Query: 1963 PD--HWG---LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
P+ H G NT LG C C C + C A G C A F+
Sbjct: 282 PNACHNGGTCFNT-LGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 340
Query: 2018 KDG-----C---DHCNCNTGYSVGFM----CNATGQCECLPGVIGEKCDR 2055
G C D C N + N C C PG G CD+
Sbjct: 341 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ 390
Score = 45.6 bits (103), Expect = 0.003
Identities = 76/296 (25%), Positives = 102/296 (34%), Gaps = 46/296 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC-DVNTGICLNCADNTIGDHCE 1794
C+C Y G +CE + PCQ H C D+ +C T+G CE
Sbjct: 1108 CECLPGYNGDNCEDDVD------ECASQPCQ---HGGSCIDLVARYLCSCPPGTLGVLCE 1158
Query: 1795 F----CMSGYHGDATV-----GTPRDCL---ICACPMPYPSNNFALSCDLSENGSLIS-- 1840
C G D+ GT D + C CP Y + +G+ +
Sbjct: 1159 INEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAH 1218
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD 1897
C PG GG RC C AG+ G T L + +PC G P PG +
Sbjct: 1219 TRDCLQDPG-GGFRC-LCHAGFSGPRCQTVLSPCE-SQPCQHGGQCRPS-PGPGGGLTFT 1274
Query: 1898 CLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGT-CVCRPGVIGE 1956
C C G C A ++C C G+ + G C C PG+ G
Sbjct: 1275 C-HCAQPFWGPRCERVA----------RSCRELQCP-VGVPCQQTPRGPRCACPPGLSGP 1322
Query: 1957 KCDRCAPDHWGL-NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAA 2011
C G N PC G + +C CA+G TG +C+ AA
Sbjct: 1323 SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFF-RCACAQGWTGPRCEAPAA 1377
Score = 44.4 bits (100), Expect = 0.008
Identities = 59/247 (23%), Positives = 84/247 (34%), Gaps = 45/247 (18%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQC---PCKPNV-----IGRTCSACRTGYYG------FP 1381
G+ C C G T C T +C PC+ IG+ C G+ G
Sbjct: 413 GSFLCQCG-RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDID 471
Query: 1382 NCRPCHCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVV 1438
C+ C + +C D NG C CP G C DV D+C P
Sbjct: 472 ECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ--------LDV----DECASTPCRN- 518
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDH----CVPGHYAFPDC------YQCTCNRHGTTYD 1488
G + + D +C C E G +CD C P C + C C G T
Sbjct: 519 GAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCAC-APGYTGT 577
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI 1548
C+ +C + G C ++Y P G T C C+S+ T+
Sbjct: 578 RCESQVDECRSQPCRHGGKCLDLVDKYL---CRCPSGTTGVNCEVNIDDCASNPCTFGVC 634
Query: 1549 DEMVDWY 1555
+ ++ Y
Sbjct: 635 RDGINRY 641
Score = 44.4 bits (100), Expect = 0.008
Identities = 44/164 (26%), Positives = 62/164 (37%), Gaps = 25/164 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGM-CICPKNVEGENCDRC 1414
G +C C+P G CS +PC T D G C CP V+G C+
Sbjct: 715 GFRCVCEPGWSGPRCSQSLAR--DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL 772
Query: 1415 KPYTFNFDVQRG-CDD-------CNCNPLGVVGNQLQCEAD--SGKCACRENVRGRVCDH 1464
P T N G C+ C+C P G G + Q + D +G C + +C +
Sbjct: 773 SPCTPNPCEHGGRCESAPGQLPVCSC-PQGWQGPRCQQDVDECAGPAPCGPH---GICTN 828
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ CTC+ G T CDQ+ C + G +C
Sbjct: 829 -------LAGSFSCTCH-GGYTGPSCDQDINDCDPNPCLNGGSC 864
Score = 42.7 bits (96), Expect = 0.024
Identities = 77/334 (23%), Positives = 111/334 (33%), Gaps = 49/334 (14%)
Query: 320 EGGGKCLN---CQHNTEGINCNKCRPTYYRPYGKRWD-ELDVCQPCQCDPHFSTGNCEEE 375
+ G +CL+ C G C C P Y G R + +++ C+ C T +C ++
Sbjct: 1171 DSGPRCLHNGTCVDLVGGFRCT-CPPGYT---GLRCEADINECRSGACHAAH-TRDCLQD 1225
Query: 376 SG---RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
G RC C F P C + P C + G T T C C +
Sbjct: 1226 PGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFT---CHCAQPFW 1282
Query: 433 GKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQA---G 487
G CE + C+ +C V C + C C SG +C G
Sbjct: 1283 GPRCE-----RVARSCRELQC----PVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPG 1333
Query: 488 YYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD------------QCLSGYY 535
N +C C G+ +C C G+ GPRC+ +C
Sbjct: 1334 ASN-ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAAC 1392
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCSAD-----GKCNCLTNFGGAQCDQCSPGYYKYPDC 590
G +R CN G CS +C L + +C P P C
Sbjct: 1393 QAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPA-CSSPAC 1451
Query: 591 LSCNCDV-SGSIGSTCDDNGLCHCKSNFDGAKCD 623
L N D +G TC+ +C +F +CD
Sbjct: 1452 LYDNFDCHAGGRERTCNPVYEKYCADHFADGRCD 1485
Score = 40.3 bits (90), Expect = 0.13
Identities = 79/301 (26%), Positives = 97/301 (32%), Gaps = 59/301 (19%)
Query: 516 CICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
C+C G+ G RC D C SG GR C S+ + +A C C F
Sbjct: 65 CLCPPGWVGERCQLEDPCHSG---PCAGRG----VCQ-----SSVVAGTARFSCRCPRGF 112
Query: 573 GGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR-- 626
G C P CLS C D LC C + G C D CR
Sbjct: 113 RGPDCSLPDP-------CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 165
Query: 627 ------EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKD----RVQGRICNDCK 676
N P C C P G T +VP C++ R G + DC
Sbjct: 166 EPCRHGGTCLNTPGSFRCQC-PAGYTGPLCENPAVPCAP-SPCRNGGTCRQSGDLTYDCA 223
Query: 677 --PLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQC-------VCKQHVGERQC- 725
P + E N C C GT + NT + QC C + V E Q
Sbjct: 224 CLPGFEGQNCEVNVDDCPGHRCLNGGT--CVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 281
Query: 726 -DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDK-TTGQCH----CHSRVEGRRCDQP 779
+ C +G T C + G S N D T C CH RV C P
Sbjct: 282 PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP 341
Query: 780 I 780
+
Sbjct: 342 M 342
Score = 39.9 bits (89), Expect = 0.17
Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 29/189 (15%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG 1398
PCL GS + +F C C P G C+ P C P C +
Sbjct: 857 PCLNG--GSCQDGVGSFS--CSCLPGFAGPRCARDVDECLSNP-CGPGTCTDHVA---SF 908
Query: 1399 MCICPKNVEGENCDR----CKPYT-FNFDV-QRGCDD--CNCNPLGVVGNQLQCEADSGK 1450
C CP G +C++ C P + FN G + C C P G G Q EAD
Sbjct: 909 TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP-GYTGAHCQHEADP-- 965
Query: 1451 CACRENVRGRVCDHCVPG-------HYAFPDCYQCT--CNRHG-TTYDVCDQNTAQCYCK 1500
C R + G VC PG + P C C+R C Q A C C
Sbjct: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP 1025
Query: 1501 TNVRGQACD 1509
G+ CD
Sbjct: 1026 PGWSGRLCD 1034
Score = 35.9 bits (79), Expect = 2.8
Identities = 52/208 (25%), Positives = 70/208 (33%), Gaps = 30/208 (14%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA----CR--TGYYGFPNCRPCHCPSTAICDDNG-MCICPK 1404
C G C C P GR C CR G + C + +D+ C+CP+
Sbjct: 1015 CVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1074
Query: 1405 NVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQCEADSGKCACREN 1456
G +C++ Q G C C C P G G+ CE D +CA +
Sbjct: 1075 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLP-GYNGD--NCEDDVDECASQPC 1131
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV-RGQAC---DTCK 1512
G C V Y C+C GT +C+ N C + G C TC
Sbjct: 1132 QHGGSCIDLVAR-------YLCSC-PPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
Query: 1513 EEYFNLQDDNPDGCTKCFCFGKTTRCSS 1540
+ + P G T C C S
Sbjct: 1184 DLVGGFRCTCPPGYTGLRCEADINECRS 1211
Score = 34.7 bits (76), Expect = 6.4
Identities = 44/169 (26%), Positives = 55/169 (32%), Gaps = 26/169 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYY----GFPNCRPCHCPSTAICDDNGM----CICPKNVE 1407
GG C P C A TG P C P C + C +G C C E
Sbjct: 171 GGTCLNTPGSFRCQCPAGYTGPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFE 229
Query: 1408 GENC----DRCKPYTF--NFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV--RG 1459
G+NC D C + G + NC Q C D +C + N G
Sbjct: 230 GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQF-CTEDVDECQLQPNACHNG 288
Query: 1460 RVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C + + GH C C +G T + C QN C G C
Sbjct: 289 GTCFNTLGGH-------SCVC-VNGWTGESCSQNIDDCATAVCFHGATC 329
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 85.4 bits (202), Expect = 3e-15
Identities = 129/527 (24%), Positives = 183/527 (34%), Gaps = 87/527 (16%)
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGR----YEGGGKCLNCQHNTEGINCNK 339
DR + C C + + T ++DE + NG G +C C EG C++
Sbjct: 446 DRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGFEGTLCDR 504
Query: 340 ----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAY 395
C P +G+ D + C C P ++ CE + C +P C
Sbjct: 505 NVDDCSPDPCH-HGRCVDGI-ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVD 562
Query: 396 GYFDYPNCKPCTCNLNGTEGEHCTPTDGLC---PCKYNYAGKSCE----ICEDGYYSPEC 448
Y C C +GT G +C C PC + +C+ G+ P C
Sbjct: 563 KYL-------CRCP-SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLC 614
Query: 449 KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN--CDTSGTEP 506
N E N S C + +C +G C C G P C P + C
Sbjct: 615 -NVEINECASSP--CGE---GGSCVDGENGFRC-LCPPGSLP-PLCLPPSHPCAHEPCSH 666
Query: 507 SICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
IC D G +C+C+ G+ GPRC Q L+ R+ C P + T CS+DG
Sbjct: 667 GICYDAPGGFRCVCEPGWSGPRCSQSLA--------RD----ACESQPCRAGGT-CSSDG 713
Query: 565 ---KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAK 621
C C G QC+ SP C C+ G S +C C + G +
Sbjct: 714 MGFHCTCPPGVQGRQCELLSP-------CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPR 766
Query: 622 CDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC----NDC-- 675
C ++ PA C P G+ + AG S C C G C NDC
Sbjct: 767 CQQDVDECAG-PA----PCGPHGICTNLAGSFS------CTCHGGYTGPSCDQDINDCDP 815
Query: 676 KPLYWNLQEYNPFGCEQCNC--NLAG--TLNSLGAC-NTKSGQCVCKQHVGERQCDQCLD 730
P + G C+C AG + C + G C HV C C
Sbjct: 816 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTC-TCPP 874
Query: 731 GFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
G+ D+ C+ C GG+ + + + C C G C
Sbjct: 875 GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFS--CLCRPGYTGAHC 919
Score = 83.0 bits (196), Expect = 2e-14
Identities = 153/585 (26%), Positives = 203/585 (34%), Gaps = 99/585 (16%)
Query: 233 CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWD-RFSC 288
C G C+ + AG CRC GP C+ C S R S D RF C
Sbjct: 47 CAGRG-VCQSSVVAGTARFS-CRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLC 104
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINCNK- 339
C C D +DE R + GG CLN C G C
Sbjct: 105 S-CPPGYQGRSCRSD--VDECR----VGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 157
Query: 340 ---CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYG 396
C P+ R G D+ C C P F NCE C P + + +C G
Sbjct: 158 AVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDG 214
Query: 397 YFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN--YAGKSCEICEDGYYSPECKNCECN 454
Y NC+ C T G+ CT C + N + G +C G+ +C C
Sbjct: 215 VNTY-NCQ---CPPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGH------SCVC- 262
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY-NYPTCKP---CNCDTSGT-----E 505
G C + DC + G TC+ A +Y P K C+ D + E
Sbjct: 263 VNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHE 322
Query: 506 PSICD--DVSGQ--CICKAGFGGPRCDQ----CLSGYY-MQVLGR---ERQCVPCNCDPT 553
+ICD V+G+ C C GF G CDQ C G + LGR + C C
Sbjct: 323 DAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG-R 381
Query: 554 GSTSTSCSAD------GKC----NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
G T C D G C CL G C C G+ C D+ S
Sbjct: 382 GYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC-ICMAGF----TGTYCEVDIDECQSS 436
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGEL 660
C + G+ CK +G C TC F +EC P + A C P G
Sbjct: 437 PCVNGGV--CKDRVNGFSC-TCPSGFSGSTCQLDVDECASTP---CRNGAKCVDQPDGYE 490
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C+C + +G +C+ N+ + +P C C + G + AC C+ V
Sbjct: 491 CRCAEGFEGTLCDR------NVDDCSPDPCHHGRC-VDGIASFSCACAPGYTGTRCESQV 543
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
E + C G L D + C C G+ NC+ C
Sbjct: 544 DECRSQPCRHGGKCLDLVDKYLC-RCP---SGTTGVNCEVNIDDC 584
Score = 68.9 bits (161), Expect = 3e-10
Identities = 93/370 (25%), Positives = 127/370 (34%), Gaps = 60/370 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVP------CQC---------NGHSDQCDV 1776
+C C + G +CE + GH L G CV CQC D+C +
Sbjct: 181 DCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQL 240
Query: 1777 NTGICLNCAD--NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN----NFALSC 1830
C N NT+G H C++G+ G++ DC C + +F +C
Sbjct: 241 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 300
Query: 1831 DLSENGSLI----SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP--CNCSGNIN 1884
+ + G L +C P + A C+ I TG C CS N
Sbjct: 301 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 360
Query: 1885 P-QDPGSCDSINGDCL-KCVNNTAGAAC----NLCAPG---FYGDAIFSKNCTACIC-DE 1934
P + G C + G L +C G C N C G + CIC
Sbjct: 361 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAG 420
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKC-DR-------CAPDHWGLNTGLGCTPCNCGIASEST 1986
F C+ C P V G C DR C G L C
Sbjct: 421 FTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGA 480
Query: 1987 QCDD--DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCEC 2044
+C D D +CRCA+G G CD+ + + D C H C G A+ C C
Sbjct: 481 KCVDQPDGYECRCAEGFEGTLCDR---NVDDCSPDPCHHGRCVDGI-------ASFSCAC 530
Query: 2045 LPGVIGEKCD 2054
PG G +C+
Sbjct: 531 APGYTGTRCE 540
Score = 68.9 bits (161), Expect = 3e-10
Identities = 92/342 (26%), Positives = 122/342 (35%), Gaps = 61/342 (17%)
Query: 1733 VEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ECQ G C+ G PSGF C D+C C N C D
Sbjct: 430 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFS-GSTCQLDVDECASTP--CRNGAKCVDQP 486
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C G+ G DC P P ++ ++ SC C PGY
Sbjct: 487 DGYECR-CAEGFEGTLCDRNVDDC------SPDPCHHGRCVDGIAS----FSCACAPGYT 535
Query: 1849 GARCEYCAAGYYGIP-----EDTDLHTGDYCK-PCNCSG---NINPQDPGSCDSINGDCL 1899
G RCE P + DL C+ P +G +N D S G C
Sbjct: 536 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 595
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
+N C +C PGF G + C + C E G C+C PG +
Sbjct: 596 DGINR---YDC-VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPL 651
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN 2015
C P H PC+ GI C D G +C C G +G +C Q A
Sbjct: 652 C--LPPSH-----PCAHEPCSHGI------CYDAPGGFRCVCEPGWSGPRCSQSLA---- 694
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCD 2054
+D C+ C G + C++ G C C PGV G +C+
Sbjct: 695 --RDACESQPCRAGGT----CSSDGMGFHCTCPPGVQGRQCE 730
Score = 68.9 bits (161), Expect = 3e-10
Identities = 145/576 (25%), Positives = 195/576 (33%), Gaps = 94/576 (16%)
Query: 236 HADTCEPADPAGNLNILVCRCQHNTCGPQC----NKCCSGFEQKKWRISQNW-DRFSCEP 290
H CE A G L VC C GP+C ++C I N FSC
Sbjct: 742 HGGRCESAP--GQLP--VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC-- 795
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
CH T + D +I++ D N GG +CQ +C+ C P + P
Sbjct: 796 -TCHGGYTGPSCDQDIND----CDPNPCLNGG----SCQDGVGSFSCS-CLPGFAGPRCA 845
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEE--SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTC 408
R ++D C C P G C + S C C P + C D P+C P +C
Sbjct: 846 R--DVDECLSNPCGP----GTCTDHVASFTCTCPPGYGGFHCEQ------DLPDCSPSSC 893
Query: 409 NLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVCDK 465
GT + C C+ Y G C+ D S C + C G +
Sbjct: 894 FNGGTCVDGVNSFS--CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 951
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGP 525
TG C++ + CQ G T C C G +CD S C A G
Sbjct: 952 FTGP-QCQTLVDWCSRQPCQNGGRCVQTGAYCLCPP-GWSGRLCDIRSLPCREAAAQIGV 1009
Query: 526 RCDQ-CLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPG 583
R +Q C +G CV C P G T + C + C G C G
Sbjct: 1010 RLEQLCQAGGQCVDEDSSHYCV---C-PEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1065
Query: 584 YYKYPDCLSCNCDVSGSIGSTCDDN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP 642
Y C C + G G C+D+ C + G C ++ C+C P
Sbjct: 1066 YM-------CEC-LPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL-------CSCPP 1110
Query: 643 R--GVTASFA--GCGSVP---AGELC----QCKDRVQGRICNDCKPLYWNLQ-EYNPFGC 690
GV CG P +G C C D V G C C P Y L+ E + C
Sbjct: 1111 GTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT-CPPGYTGLRCEADINEC 1169
Query: 691 EQCNCNLAGTLNSLGACNTKSG-QCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD 749
C+ A T + L + G +C+C +C L C C
Sbjct: 1170 RSGACHAAHTRDCLQ--DPGGGFRCLCHAGFSGPRCQTVLSP-----------CESQPCQ 1216
Query: 750 IGGSIDNNCDKTTG---QCHCHSRVEGRRCDQPIRA 782
GG + G CHC G RC++ R+
Sbjct: 1217 HGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARS 1252
Score = 68.5 bits (160), Expect = 4e-10
Identities = 107/440 (24%), Positives = 138/440 (31%), Gaps = 61/440 (13%)
Query: 360 PCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEH 417
PC P G C G CEC P + +C D C C G+ +
Sbjct: 1047 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED------DVDECASQPCQHGGSCIDL 1100
Query: 418 CTPTDGLCPCKYNYAGKSCEICED--GYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
LC C G CEI ED G P C G+ C L G CTC
Sbjct: 1101 VARY--LCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT----CVDLVGGFRCTCP 1154
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLS 532
Y+G C + C+ C + T + D G +C+C AGF GPRC LS
Sbjct: 1155 PGYTGLRCEA------DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLS 1208
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Q QC P G T T C+C F G +C++ + C
Sbjct: 1209 PCESQPCQHGGQCRPSPGPGGGLTFT-------CHCAQPFWGPRCERVA------RSCRE 1255
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC 652
C V T C C G +CR + P +C C
Sbjct: 1256 LQCPVGVPCQQT-PRGPRCACPPGLSG---PSCRSFPGSPPGASNASC-AAAPCLHGGSC 1310
Query: 653 GSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA-------GTLNSLG 705
P +C QG C+ + C + C NS G
Sbjct: 1311 RPAPLAPFFRCA-CAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1369
Query: 706 ACNTKSGQCVCKQHVGERQCD--QCLDGFYRLQTNDVFGCTEC-----DCDIGGSIDNNC 758
C G C RQC+ QC F + + C DC GG + C
Sbjct: 1370 -CGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGR-ERTC 1427
Query: 759 DKTTGQCHCHSRVEGRRCDQ 778
+ + +C RCDQ
Sbjct: 1428 NPVY-EKYCADHFADGRCDQ 1446
Score = 68.1 bits (159), Expect = 6e-10
Identities = 97/377 (25%), Positives = 133/377 (35%), Gaps = 69/377 (18%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCV------PCQCNG-------HSDQCDVNT 1778
C CP+ ++G C+Q CA P G C C C+G D D +
Sbjct: 756 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 815
Query: 1779 GICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
CLN C D C C+ G+ G +CL C P +C +++
Sbjct: 816 NPCLNGGSCQDGVGSFSCS-CLPGFAGPRCARDVDECLSNPCG---PG-----TC--TDH 864
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPE--DTDLHTGDYCKP--CNCSGNINPQDPGS- 1890
+ +C C PGYGG CE +P+ + G C + S P G+
Sbjct: 865 VASFTCTCPPGYGGFHCE------QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAH 918
Query: 1891 CDSINGDCLK--CVNNTAGAACNLCAPGFYGDAIFSKNCTAC--ICDEFGMADCDS---- 1942
C CL C++ G C+ PGF + S C + D C +
Sbjct: 919 CQHEADPCLSRPCLH---GGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC 975
Query: 1943 --TTGTCVCRPGVIGEKCD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAK 1999
T C+C PG G CD R P +G A +D + C C +
Sbjct: 976 VQTGAYCLCPPGWSGRLCDIRSLPCREAA-AQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1034
Query: 2000 GVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
G TG C+Q C H GY G+M CECLPG G+ C+ +
Sbjct: 1035 GRTGSHCEQEVD---PCLAQPCQHGGTCRGYMGGYM------CECLPGYNGDNCEDDVDE 1085
Query: 2060 WVLIPQEGCLECDSCTD 2076
P C SC D
Sbjct: 1086 CASQP---CQHGGSCID 1099
Score = 66.5 bits (155), Expect = 2e-09
Identities = 93/371 (25%), Positives = 131/371 (35%), Gaps = 64/371 (17%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC+C + G C++ + C P C+ H D CA G CE
Sbjct: 490 ECRCAEGFEGTLCDRNVDD--------CSPDPCH-HGRCVDGIASFSCACAPGYTGTRCE 540
Query: 1795 F----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCD----------LSENG-S 1837
C S HG + D +C CP N ++ D + +G +
Sbjct: 541 SQVDECRSQPCRHGGKCLDLV-DKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGIN 599
Query: 1838 LISCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPCNCS-GNINPQD-PGSC 1891
C CQPG+ G C CA+ G E G+ C C G++ P P S
Sbjct: 600 RYDCVCQPGFTGPLCNVEINECASSPCG--EGGSCVDGENGFRCLCPPGSLPPLCLPPSH 657
Query: 1892 DSINGDCLK--CVNNTAGAACNLCAPGFYG----DAIFSKNCTACICDEFGMADCDSTTG 1945
+ C C + G C +C PG+ G ++ C + C G D
Sbjct: 658 PCAHEPCSHGICYDAPGGFRC-VCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF 716
Query: 1946 TCVCRPGVIGEKCDRCAP------DHWG-LNTGLGCTP-CNCGIASESTQCDDDNGQCRC 1997
C C PGV G +C+ +P +H G + G P C+C + +C D +C
Sbjct: 717 HCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDEC-A 775
Query: 1998 AKGVTGKQ--CDQCAAGF-----WNYTKDGCDH----CNCNTGYSVGFMCNATG--QCEC 2044
G C A F YT CD C+ N + G + G C C
Sbjct: 776 GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC 835
Query: 2045 LPGVIGEKCDR 2055
LPG G +C R
Sbjct: 836 LPGFAGPRCAR 846
Score = 58.4 bits (135), Expect = 5e-07
Identities = 92/360 (25%), Positives = 126/360 (35%), Gaps = 77/360 (21%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG--ICLNCADNTIGDHC 1793
C+CPR +RG C LP C+ C H +C V +C G C
Sbjct: 66 CRCPRGFRGPDCS--------LPDP-CLSSPC-AHGARCSVGPDGRFLCSCPPGYQGRSC 115
Query: 1794 ----EFCMSG---YHGDATVGTPRDCLICACPMPYPS---NNFALSCDLS---------E 1834
+ C G HG + TP C CP Y N A+ C S +
Sbjct: 116 RSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQ 174
Query: 1835 NGSL-ISCNCQPGYGGARCEY---CAAGYYGIPEDT---DLHTGDYCKPCNCSGNINPQD 1887
+G L C C PG+ G CE G+ + T ++T + P +G +D
Sbjct: 175 SGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTED 234
Query: 1888 PGSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDS 1942
C C C N G +C +C G+ G++ +C +C F A C
Sbjct: 235 VDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCSQNIDDCATAVC--FHGATCHD 291
Query: 1943 TTGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CR 1996
+ C C G G C L+ PC+ E CD + NG+ C
Sbjct: 292 RVASFYCACPMGKTGLLCH--------LDDACVSNPCH-----EDAICDTNPVNGRAICT 338
Query: 1997 CAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCD 2054
C G TG CDQ D C N +G N G C+C G G +C+
Sbjct: 339 CPPGFTGGACDQ--------DVDECS-IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE 389
Score = 52.0 bits (119), Expect = 4e-05
Identities = 97/376 (25%), Positives = 131/376 (34%), Gaps = 66/376 (17%)
Query: 1736 CQCPRAYRGLSCEQ----CAE------GHYRLPSGFCVPCQC-NGHSDQ-CDVNTGIC-- 1781
CQCP Y G CE CA G R C C G Q C+VN C
Sbjct: 143 CQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPG 202
Query: 1782 ---LN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
LN C D +C+ C + G +C + P +N +C +
Sbjct: 203 HRCLNGGTCVDGVNTYNCQ-CPPEWTGQFCTEDVDECQL----QPNACHNGG-TCFNTLG 256
Query: 1836 GSLISCNCQPGYGGARCEY----CAAG--YYGIPEDTDLHTGDYCK-PCNCSGNINPQDP 1888
G SC C G+ G C CA ++G D YC P +G + D
Sbjct: 257 GH--SCVCVNGWTGESCSQNIDDCATAVCFHGATCH-DRVASFYCACPMGKTGLLCHLDD 313
Query: 1889 GSCDS-INGDCLKCVNNTAGAACNLCAPGFYGDAIFSK--NCT--ACICDEFGMADCDST 1943
+ + D + N G A C PGF G A C+ A C+ G C +T
Sbjct: 314 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGR--CVNT 371
Query: 1944 TGT--CVCRPGVIGEKCDR---------CAPDHWGLNTGLGCTPCNCGIASESTQCDDDN 1992
G+ C C G G +C+ C L+ +G C C T C+ D
Sbjct: 372 QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDR-IGQFTCICMAGFTGTYCEVDI 430
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGE 2051
+C+ + V G C GF C C +G+S G C +C P G
Sbjct: 431 DECQSSPCVNGGVCKDRVNGF---------SCTCPSGFS-GSTCQLDVDECASTPCRNGA 480
Query: 2052 KCDRCPERWVLIPQEG 2067
KC P+ + EG
Sbjct: 481 KCVDQPDGYECRCAEG 496
Score = 48.8 bits (111), Expect = 4e-04
Identities = 89/346 (25%), Positives = 116/346 (33%), Gaps = 63/346 (18%)
Query: 1736 CQCPRAYRGLSCE----QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP + G C+ C E ++ CQ G D ++ C+ C + G
Sbjct: 982 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED-SSHYCV-CPEGRTGS 1039
Query: 1792 HCEF----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
HCE C++ HG G + C C Y +N C+ + C QP
Sbjct: 1040 HCEQEVDPCLAQPCQHGGTCRGYMGGYM-CECLPGYNGDN----CE----DDVDECASQP 1090
Query: 1846 GYGGARCEYCAAGYY-GIPEDTDLHTGDYCK--PCNCSGNINPQDPGSCDSINGDCLKCV 1902
G C A Y P T G C+ +C G P D G NG C+ V
Sbjct: 1091 CQHGGSCIDLVARYLCSCPPGT---LGVLCEINEDDC-GPGPPLDSGPRCLHNGTCVDLV 1146
Query: 1903 NNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTG---TCVCRPGVIGEK 1957
G C C PG+ G + C + C DC G C+C G G +
Sbjct: 1147 G---GFRCT-CPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPR 1202
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGK---QCDQCAAGFW 2014
C +PC ES C GQCR + G G C CA FW
Sbjct: 1203 CQTVL------------SPC------ESQPCQH-GGQCRPSPGPGGGLTFTC-HCAQPFW 1242
Query: 2015 NYTKDGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCP 2057
+ VG C T + C C PG+ G C P
Sbjct: 1243 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFP 1288
Score = 48.0 bits (109), Expect = 6e-04
Identities = 58/249 (23%), Positives = 87/249 (34%), Gaps = 27/249 (10%)
Query: 1840 SCNCQPGYGGARCEY---CAAGYY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
+C C PG+ G RC+ C +G G+ + + + G C C D D
Sbjct: 24 ACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVV-AGTARFSCRCPRGFRGPDCSLPDP 82
Query: 1894 -INGDCL---KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
++ C +C G C PG+ G ++C + + DE + + GTC+
Sbjct: 83 CLSSPCAHGARCSVGPDGRFLCSCPPGYQG-----RSCRSDV-DECRVGEPCRHGGTCLN 136
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
PG +C N + C P C Q D C C G G+ C+
Sbjct: 137 TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE-- 194
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCL 2069
D C C G + N T C+C P G+ C + L P C
Sbjct: 195 ------VNVDDCPGHRCLNGGTCVDGVN-TYNCQCPPEWTGQFCTEDVDECQLQP-NACH 246
Query: 2070 ECDSCTDAL 2078
+C + L
Sbjct: 247 NGGTCFNTL 255
Score = 46.8 bits (106), Expect = 0.001
Identities = 88/350 (25%), Positives = 112/350 (32%), Gaps = 65/350 (18%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEF---CMSG-------YHGDATVGTPRDCL 1813
PC G Q CL C +G+ C+ C SG GT R
Sbjct: 8 PCANGGRCTQLPSREAACL-CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSC 66
Query: 1814 ICA-------CPMPYPSNNFALS----CDLSENGSLISCNCQPGYGGARC----EYCAAG 1858
C C +P P + + C + +G + C+C PGY G C + C G
Sbjct: 67 RCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFL-CSCPPGYQGRSCRSDVDECRVG 125
Query: 1859 YYGIPEDTDLHT-GDYCKPCN-------CSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
T L+T G + C C P P C + G C + + T AC
Sbjct: 126 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRN-GGTCRQSGDLTYDCAC 184
Query: 1911 NLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC----DRCA-- 1962
PGF G + +C C G T C C P G+ C D C
Sbjct: 185 ---LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 241
Query: 1963 PD--HWG---LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
P+ H G NT LG C C C + C A G C A F+
Sbjct: 242 PNACHNGGTCFNT-LGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 300
Query: 2018 KDG-----C---DHCNCNTGYSVGFM----CNATGQCECLPGVIGEKCDR 2055
G C D C N + N C C PG G CD+
Sbjct: 301 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ 350
Score = 45.6 bits (103), Expect = 0.003
Identities = 76/296 (25%), Positives = 102/296 (34%), Gaps = 46/296 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQC-DVNTGICLNCADNTIGDHCE 1794
C+C Y G +CE + PCQ H C D+ +C T+G CE
Sbjct: 1068 CECLPGYNGDNCEDDVD------ECASQPCQ---HGGSCIDLVARYLCSCPPGTLGVLCE 1118
Query: 1795 F----CMSGYHGDATV-----GTPRDCL---ICACPMPYPSNNFALSCDLSENGSLIS-- 1840
C G D+ GT D + C CP Y + +G+ +
Sbjct: 1119 INEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAH 1178
Query: 1841 ---CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGD 1897
C PG GG RC C AG+ G T L + +PC G P PG +
Sbjct: 1179 TRDCLQDPG-GGFRC-LCHAGFSGPRCQTVLSPCE-SQPCQHGGQCRPS-PGPGGGLTFT 1234
Query: 1898 CLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGT-CVCRPGVIGE 1956
C C G C A ++C C G+ + G C C PG+ G
Sbjct: 1235 C-HCAQPFWGPRCERVA----------RSCRELQCP-VGVPCQQTPRGPRCACPPGLSGP 1282
Query: 1957 KCDRCAPDHWGL-NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAA 2011
C G N PC G + +C CA+G TG +C+ AA
Sbjct: 1283 SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFF-RCACAQGWTGPRCEAPAA 1337
Score = 44.4 bits (100), Expect = 0.008
Identities = 59/247 (23%), Positives = 84/247 (34%), Gaps = 45/247 (18%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQC---PCKPNV-----IGRTCSACRTGYYG------FP 1381
G+ C C G T C T +C PC+ IG+ C G+ G
Sbjct: 373 GSFLCQCG-RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDID 431
Query: 1382 NCRPCHCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVV 1438
C+ C + +C D NG C CP G C DV D+C P
Sbjct: 432 ECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ--------LDV----DECASTPCRN- 478
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDH----CVPGHYAFPDC------YQCTCNRHGTTYD 1488
G + + D +C C E G +CD C P C + C C G T
Sbjct: 479 GAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCAC-APGYTGT 537
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI 1548
C+ +C + G C ++Y P G T C C+S+ T+
Sbjct: 538 RCESQVDECRSQPCRHGGKCLDLVDKYL---CRCPSGTTGVNCEVNIDDCASNPCTFGVC 594
Query: 1549 DEMVDWY 1555
+ ++ Y
Sbjct: 595 RDGINRY 601
Score = 44.4 bits (100), Expect = 0.008
Identities = 44/164 (26%), Positives = 62/164 (37%), Gaps = 25/164 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGM-CICPKNVEGENCDRC 1414
G +C C+P G CS +PC T D G C CP V+G C+
Sbjct: 675 GFRCVCEPGWSGPRCSQSLAR--DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL 732
Query: 1415 KPYTFNFDVQRG-CDD-------CNCNPLGVVGNQLQCEAD--SGKCACRENVRGRVCDH 1464
P T N G C+ C+C P G G + Q + D +G C + +C +
Sbjct: 733 SPCTPNPCEHGGRCESAPGQLPVCSC-PQGWQGPRCQQDVDECAGPAPCGPH---GICTN 788
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+ CTC+ G T CDQ+ C + G +C
Sbjct: 789 -------LAGSFSCTCH-GGYTGPSCDQDINDCDPNPCLNGGSC 824
Score = 42.7 bits (96), Expect = 0.024
Identities = 77/334 (23%), Positives = 111/334 (33%), Gaps = 49/334 (14%)
Query: 320 EGGGKCLN---CQHNTEGINCNKCRPTYYRPYGKRWD-ELDVCQPCQCDPHFSTGNCEEE 375
+ G +CL+ C G C C P Y G R + +++ C+ C T +C ++
Sbjct: 1131 DSGPRCLHNGTCVDLVGGFRCT-CPPGYT---GLRCEADINECRSGACHAAH-TRDCLQD 1185
Query: 376 SG---RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
G RC C F P C + P C + G T T C C +
Sbjct: 1186 PGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFT---CHCAQPFW 1242
Query: 433 GKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQA---G 487
G CE + C+ +C V C + C C SG +C G
Sbjct: 1243 GPRCE-----RVARSCRELQC----PVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPG 1293
Query: 488 YYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD------------QCLSGYY 535
N +C C G+ +C C G+ GPRC+ +C
Sbjct: 1294 ASN-ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAAC 1352
Query: 536 MQVLGRERQCVPCNCDPTGSTSTSCSAD-----GKCNCLTNFGGAQCDQCSPGYYKYPDC 590
G +R CN G CS +C L + +C P P C
Sbjct: 1353 QAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPA-CSSPAC 1411
Query: 591 LSCNCDV-SGSIGSTCDDNGLCHCKSNFDGAKCD 623
L N D +G TC+ +C +F +CD
Sbjct: 1412 LYDNFDCHAGGRERTCNPVYEKYCADHFADGRCD 1445
Score = 40.3 bits (90), Expect = 0.13
Identities = 79/301 (26%), Positives = 97/301 (32%), Gaps = 59/301 (19%)
Query: 516 CICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
C+C G+ G RC D C SG GR C S+ + +A C C F
Sbjct: 25 CLCPPGWVGERCQLEDPCHSG---PCAGRG----VCQ-----SSVVAGTARFSCRCPRGF 72
Query: 573 GGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR-- 626
G C P CLS C D LC C + G C D CR
Sbjct: 73 RGPDCSLPDP-------CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 125
Query: 627 ------EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKD----RVQGRICNDCK 676
N P C C P G T +VP C++ R G + DC
Sbjct: 126 EPCRHGGTCLNTPGSFRCQC-PAGYTGPLCENPAVPCAP-SPCRNGGTCRQSGDLTYDCA 183
Query: 677 --PLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQC-------VCKQHVGERQC- 725
P + E N C C GT + NT + QC C + V E Q
Sbjct: 184 CLPGFEGQNCEVNVDDCPGHRCLNGGT--CVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 241
Query: 726 -DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDK-TTGQCH----CHSRVEGRRCDQP 779
+ C +G T C + G S N D T C CH RV C P
Sbjct: 242 PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP 301
Query: 780 I 780
+
Sbjct: 302 M 302
Score = 39.9 bits (89), Expect = 0.17
Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 29/189 (15%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG 1398
PCL GS + +F C C P G C+ P C P C +
Sbjct: 817 PCLNG--GSCQDGVGSFS--CSCLPGFAGPRCARDVDECLSNP-CGPGTCTDHVA---SF 868
Query: 1399 MCICPKNVEGENCDR----CKPYT-FNFDV-QRGCDD--CNCNPLGVVGNQLQCEADSGK 1450
C CP G +C++ C P + FN G + C C P G G Q EAD
Sbjct: 869 TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP-GYTGAHCQHEADP-- 925
Query: 1451 CACRENVRGRVCDHCVPG-------HYAFPDCYQCT--CNRHG-TTYDVCDQNTAQCYCK 1500
C R + G VC PG + P C C+R C Q A C C
Sbjct: 926 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP 985
Query: 1501 TNVRGQACD 1509
G+ CD
Sbjct: 986 PGWSGRLCD 994
Score = 35.9 bits (79), Expect = 2.8
Identities = 52/208 (25%), Positives = 70/208 (33%), Gaps = 30/208 (14%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA----CR--TGYYGFPNCRPCHCPSTAICDDNG-MCICPK 1404
C G C C P GR C CR G + C + +D+ C+CP+
Sbjct: 975 CVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1034
Query: 1405 NVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQCEADSGKCACREN 1456
G +C++ Q G C C C P G G+ CE D +CA +
Sbjct: 1035 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLP-GYNGD--NCEDDVDECASQPC 1091
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV-RGQAC---DTCK 1512
G C V Y C+C GT +C+ N C + G C TC
Sbjct: 1092 QHGGSCIDLVAR-------YLCSC-PPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1143
Query: 1513 EEYFNLQDDNPDGCTKCFCFGKTTRCSS 1540
+ + P G T C C S
Sbjct: 1144 DLVGGFRCTCPPGYTGLRCEADINECRS 1171
Score = 34.7 bits (76), Expect = 6.4
Identities = 44/169 (26%), Positives = 55/169 (32%), Gaps = 26/169 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYY----GFPNCRPCHCPSTAICDDNGM----CICPKNVE 1407
GG C P C A TG P C P C + C +G C C E
Sbjct: 131 GGTCLNTPGSFRCQCPAGYTGPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFE 189
Query: 1408 GENC----DRCKPYTF--NFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV--RG 1459
G+NC D C + G + NC Q C D +C + N G
Sbjct: 190 GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQF-CTEDVDECQLQPNACHNG 248
Query: 1460 RVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C + + GH C C +G T + C QN C G C
Sbjct: 249 GTCFNTLGGH-------SCVC-VNGWTGESCSQNIDDCATAVCFHGATC 289
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 83.8 bits (198), Expect = 1e-14
Identities = 120/486 (24%), Positives = 174/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 624
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 625 EVPLCA 630
Score = 74.1 bits (174), Expect = 9e-12
Identities = 170/649 (26%), Positives = 226/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 529 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 576
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 577 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 632 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 687
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 688 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PTG T SC A C +CL
Sbjct: 806 LRPSCADSPCRNRATCQDSPQGPRCLC-PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
Query: 574 GAQCDQCSPGY------YKYPDC----LSCNCDVSGSI--GSTCDDNG---LCHCKSNFD 618
C C G+ C LS DVS G C D+G CHC F
Sbjct: 865 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 924 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 966
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 967 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1014
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1015 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Score = 69.3 bits (162), Expect = 2e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 478 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 535
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 536 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 709 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 818
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 819 --ATCQDSPQGPRCLCPTGYTGGSC 841
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 945 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 998
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 999 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1099
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1100 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1159
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1160 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1218
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1219 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1247
Score = 67.7 bits (158), Expect = 7e-10
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 736 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 789
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 790 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGSCQ 842
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 843 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 954 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1004
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1063
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1064 TAGS-PLGFICHCPKGFEGPTCSHRAP 1089
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 512
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 513 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 571 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 620
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 676
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 677 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 729
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 785
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 786 PGTFSCLCAMGFQGPRC 802
Score = 57.6 bits (133), Expect = 8e-07
Identities = 86/351 (24%), Positives = 121/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 715 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 764
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 765 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C GY G T + D C C N + G + CL C+
Sbjct: 824 SPQGPRC-LCPTGYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 874
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 934
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 993
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 462
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 463 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 513
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 571
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 572 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 750 GYYCTCPPSHTGPQCQTSTD 769
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 830 CLCPTGYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 868
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 869 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 928 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 984 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1042
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1043 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1095 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1145
Query: 2074 CTD 2076
C++
Sbjct: 1146 CSE 1148
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 43.2 bits (97), Expect = 0.018
Identities = 83/346 (23%), Positives = 121/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 704
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 705 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 760
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 761 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 816
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC G+ G + C C + C+C G
Sbjct: 817 NRATCQDSPQGPRC-LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 875
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 876 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 931
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 932 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 967
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 40.7 bits (91), Expect = 0.097
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 677 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 734
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 735 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 787
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 788 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGS 840
Query: 1508 CDT 1510
C T
Sbjct: 841 CQT 843
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 916 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1028
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1029 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 610
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 611 FFCLCPSGFTGQLCE 625
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 83.8 bits (198), Expect = 1e-14
Identities = 120/486 (24%), Positives = 174/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 624
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 625 EVPLCA 630
Score = 69.3 bits (162), Expect = 2e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 478 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 535
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 536 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 709 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 818
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 819 --ATCQDSPQGPRCLCPTGYTGGSC 841
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 65.3 bits (152), Expect = 4e-09
Identities = 109/443 (24%), Positives = 157/443 (35%), Gaps = 82/443 (18%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 529 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 576
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 577 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 632 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 687
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCD 500
CE G +S C + +G +CTC + Y+G TC++ ++ P +C+
Sbjct: 688 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 501 TSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSC 560
S P C C GP+C Q + Y CV C G T +
Sbjct: 746 PS---PG-----GYYCTCPPSHTGPQC-QTSTDY----------CVSAPCF-NGGTCVNR 785
Query: 561 SADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN---GLCHCKSNF 617
C C F G +C+ G + P C C +TC D+ C C + +
Sbjct: 786 PGTFSCLCAMGFQGPRCE----GKLR-PSCADSPC----RNRATCQDSPQGPRCLCPTGY 836
Query: 618 DGAKCDTCREQFYNYPACEECNC 640
G C T + P +C
Sbjct: 837 TGGSCQTLMDLCAQRPCPRNSHC 859
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 512
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 513 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 571 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 620
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 676
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 677 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 729
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 785
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 786 PGTFSCLCAMGFQGPRC 802
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAQLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 462
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 463 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 513
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 571
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 572 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 750 GYYCTCPPSHTGPQCQTSTD 769
Score = 52.0 bits (119), Expect = 4e-05
Identities = 84/355 (23%), Positives = 114/355 (32%), Gaps = 59/355 (16%)
Query: 1736 CQCPRAYRGLSCEQ---------CAEGHYRLPSGFCVPCQCN-GHSDQ-CDVNTGIC--- 1781
C CP Y G CE C G L C C G Q C+V T C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASA 520
Query: 1782 --LN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENG 1836
LN C D G C C+ G+ G +C C A +
Sbjct: 521 PCLNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPC---------ANGGQCQDQP 570
Query: 1837 SLISCNCQPGYGGARCEY----CAAGYYGIPEDT-DLHTGDYCK-PCNCSGNINPQDPGS 1890
C C PG+ G RC+ C + + DL +C P +G + + P
Sbjct: 571 GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLC-EVPLC 629
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCT---------ACICDE-FGMADC 1940
++ C + A C LC G G A NCT +C+CD + +C
Sbjct: 630 APNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPEC 688
Query: 1941 DSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
++ G C+ P G C P G N C C C ++ C
Sbjct: 689 EAELGGCISAPCAHG---GTCYPQPSGYN-------CTCPTGYTGPTCSEEMTACHSGPC 738
Query: 2001 VTGKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+ G C+ G++ C +T Y V C G C PG C
Sbjct: 739 LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC 793
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAQL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 44.0 bits (99), Expect = 0.010
Identities = 61/242 (25%), Positives = 80/242 (33%), Gaps = 49/242 (20%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 736 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 789
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 790 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGSCQ 842
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 843 TLMDLCAQRPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 536 MQ 537
Q
Sbjct: 954 CQ 955
Score = 42.3 bits (95), Expect = 0.032
Identities = 56/236 (23%), Positives = 78/236 (33%), Gaps = 36/236 (15%)
Query: 1736 CQCPRAYRGLSCEQ---------CAEGHYRLPS--GFCVPCQCNGHSDQCDVNTGICLNC 1784
C CP Y G +C + C G PS G+ C + QC +T C++
Sbjct: 715 CTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA 774
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCN 1842
C ++G V P C C M + P L +++
Sbjct: 775 P-------C------FNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRAT 820
Query: 1843 CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCV 1902
CQ G RC C GY G T + D C C N + G + CL C+
Sbjct: 821 CQDSPQGPRC-LCPTGYTGGSCQTLM---DLCAQRPCPRNSHCLQTGP----SFHCL-CL 871
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
G CNL A+ + +C G+ + C C PG G C
Sbjct: 872 QGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAQLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 40.7 bits (91), Expect = 0.097
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 677 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 734
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 735 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 787
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 788 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGS 840
Query: 1508 CDT 1510
C T
Sbjct: 841 CQT 843
Score = 39.5 bits (88), Expect = 0.22
Identities = 75/290 (25%), Positives = 102/290 (35%), Gaps = 44/290 (15%)
Query: 1728 RRATSVEECQCPRAYRGLSCEQCAEGHYRL-PSGFCVP-CQCNGHSDQCDVNTGICLNCA 1785
R T V+EC G SC + L PSGF C+ + IC +
Sbjct: 585 RCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQK 644
Query: 1786 DNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
D +C C G G A P D C C + + + CD+ G C+
Sbjct: 645 DKA---NC-LCPDGSPGCAP---PEDN--CTCHHGHCQRSSCV-CDVGWTGP----ECEA 690
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLH----TGDYCKPCNCSGNINPQDPGSCDSINGDCLKC 1901
GG CA G P+ + + TG Y P CS + G C +NG C
Sbjct: 691 ELGGCISAPCAHGGTCYPQPSGYNCTCPTG-YTGP-TCSEEMTACHSGPC--LNGG--SC 744
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
+ G C C P G + C + C F C + GT C+C G G +
Sbjct: 745 NPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC--FNGGTCVNRPGTFSCLCAMGFQGPR 801
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQC 2006
C+ L +PC + +T D G +C C G TG C
Sbjct: 802 CE------GKLRPSCADSPCR----NRATCQDSPQGPRCLCPTGYTGGSC 841
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 610
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 611 FFCLCPSGFTGQLCE 625
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.8 bits (198), Expect = 1e-14
Identities = 120/486 (24%), Positives = 174/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 624
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 625 EVPLCA 630
Score = 74.1 bits (174), Expect = 9e-12
Identities = 170/649 (26%), Positives = 226/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 529 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 576
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 577 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 632 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 687
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 688 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PTG T SC A C +CL
Sbjct: 806 LRPSCADSPCRNRATCQDSPQGPRCLC-PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
Query: 574 GAQCDQCSPGY------YKYPDC----LSCNCDVSGSI--GSTCDDNG---LCHCKSNFD 618
C C G+ C LS DVS G C D+G CHC F
Sbjct: 865 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 924 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 966
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 967 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1014
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1015 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Score = 69.3 bits (162), Expect = 2e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 478 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 535
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 536 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 709 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 818
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 819 --ATCQDSPQGPRCLCPTGYTGGSC 841
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 945 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 998
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 999 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1099
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1100 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1159
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1160 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1218
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1219 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1247
Score = 67.7 bits (158), Expect = 7e-10
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 736 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 789
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 790 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGSCQ 842
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 843 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 954 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1004
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1063
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1064 TAGS-PLGFICHCPKGFEGPTCSHRAP 1089
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 512
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 513 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 571 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 620
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 676
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 677 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 729
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 785
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 786 PGTFSCLCAMGFQGPRC 802
Score = 57.6 bits (133), Expect = 8e-07
Identities = 86/351 (24%), Positives = 121/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 715 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 764
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 765 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C GY G T + D C C N + G + CL C+
Sbjct: 824 SPQGPRC-LCPTGYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 874
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 934
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 993
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 462
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 463 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 513
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 571
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 572 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 750 GYYCTCPPSHTGPQCQTSTD 769
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 830 CLCPTGYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 868
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 869 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 928 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 984 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1042
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1043 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1095 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1145
Query: 2074 CTD 2076
C++
Sbjct: 1146 CSE 1148
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 43.2 bits (97), Expect = 0.018
Identities = 83/346 (23%), Positives = 121/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 704
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 705 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 760
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 761 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 816
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC G+ G + C C + C+C G
Sbjct: 817 NRATCQDSPQGPRC-LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 875
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 876 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 931
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 932 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 967
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 40.7 bits (91), Expect = 0.097
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 677 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 734
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 735 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 787
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 788 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGS 840
Query: 1508 CDT 1510
C T
Sbjct: 841 CQT 843
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 916 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1028
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1029 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 610
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 611 FFCLCPSGFTGQLCE 625
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.8 bits (198), Expect = 1e-14
Identities = 120/486 (24%), Positives = 174/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 624
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 625 EVPLCA 630
Score = 74.1 bits (174), Expect = 9e-12
Identities = 170/649 (26%), Positives = 226/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 529 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 576
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 577 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 632 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 687
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 688 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PTG T SC A C +CL
Sbjct: 806 LRPSCADSPCRNRATCQDSPQGPRCLC-PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
Query: 574 GAQCDQCSPGY------YKYPDC----LSCNCDVSGSI--GSTCDDNG---LCHCKSNFD 618
C C G+ C LS DVS G C D+G CHC F
Sbjct: 865 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 924 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 966
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 967 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1014
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1015 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Score = 69.3 bits (162), Expect = 2e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 478 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 535
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 536 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 709 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 818
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 819 --ATCQDSPQGPRCLCPTGYTGGSC 841
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 945 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 998
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 999 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1099
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1100 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1159
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1160 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1218
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1219 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1247
Score = 67.7 bits (158), Expect = 7e-10
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 736 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 789
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 790 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGSCQ 842
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 843 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 954 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1004
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1063
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1064 TAGS-PLGFICHCPKGFEGPTCSHRAP 1089
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 512
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 513 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 571 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 620
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 676
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 677 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 729
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 785
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 786 PGTFSCLCAMGFQGPRC 802
Score = 57.6 bits (133), Expect = 8e-07
Identities = 86/351 (24%), Positives = 121/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 715 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 764
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 765 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C GY G T + D C C N + G + CL C+
Sbjct: 824 SPQGPRC-LCPTGYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 874
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 934
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 993
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 462
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 463 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 513
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 571
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 572 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 750 GYYCTCPPSHTGPQCQTSTD 769
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 830 CLCPTGYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 868
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 869 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 928 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 984 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1042
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1043 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1095 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1145
Query: 2074 CTD 2076
C++
Sbjct: 1146 CSE 1148
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 43.2 bits (97), Expect = 0.018
Identities = 83/346 (23%), Positives = 121/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 704
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 705 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 760
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 761 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 816
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC G+ G + C C + C+C G
Sbjct: 817 NRATCQDSPQGPRC-LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 875
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 876 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 931
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 932 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 967
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 40.7 bits (91), Expect = 0.097
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 677 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 734
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 735 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 787
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 788 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGS 840
Query: 1508 CDT 1510
C T
Sbjct: 841 CQT 843
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 916 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1028
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1029 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 610
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 611 FFCLCPSGFTGQLCE 625
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.8 bits (198), Expect = 1e-14
Identities = 120/486 (24%), Positives = 174/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 624
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 625 EVPLCA 630
Score = 68.9 bits (161), Expect = 3e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 478 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 535
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 536 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 709 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 818
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 819 --ATCQDSPQGPRCLCPTVYTGGSC 841
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 945 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 998
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 999 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1099
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1100 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1159
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1160 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1218
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1219 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1247
Score = 67.7 bits (158), Expect = 7e-10
Identities = 164/649 (25%), Positives = 221/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 529 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 576
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 577 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 632 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 687
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 688 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PT T SC A C +CL
Sbjct: 806 LRPSCADSPCRNRATCQDSPQGPRCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
Query: 574 GAQCDQCSPGY------YKYPDCLSCNCDVSGSIGSTCDDNGL---------CHCKSNFD 618
C C G+ C + S C + GL CHC F
Sbjct: 865 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 924 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 966
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 967 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1014
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1015 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 66.5 bits (155), Expect = 2e-09
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 736 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 789
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 790 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTVYTGGSCQ 842
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 843 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 954 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1004
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1063
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1064 TAGS-PLGFICHCPKGFEGPTCSHRAP 1089
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 512
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 513 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 571 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 620
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 676
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 677 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 729
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 785
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 786 PGTFSCLCAMGFQGPRC 802
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 462
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 463 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 513
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 571
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 572 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 750 GYYCTCPPSHTGPQCQTSTD 769
Score = 54.0 bits (124), Expect = 1e-05
Identities = 85/351 (24%), Positives = 120/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 715 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 764
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 765 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C Y G T + D C C N + G + CL C+
Sbjct: 824 SPQGPRC-LCPTVYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 874
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 934
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 993
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 830 CLCPTVYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 868
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 869 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 928 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 984 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1042
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1043 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1095 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1145
Query: 2074 CTD 2076
C++
Sbjct: 1146 CSE 1148
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 39.5 bits (88), Expect = 0.22
Identities = 82/346 (23%), Positives = 120/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 704
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 705 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 760
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 761 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 816
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC + G + C C + C+C G
Sbjct: 817 NRATCQDSPQGPRC-LCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 875
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 876 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 931
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 932 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 967
Score = 39.5 bits (88), Expect = 0.22
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 677 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 734
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 735 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 787
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 788 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTVYTGGS 840
Query: 1508 CDT 1510
C T
Sbjct: 841 CQT 843
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 916 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1028
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1029 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 610
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 611 FFCLCPSGFTGQLCE 625
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.8 bits (198), Expect = 1e-14
Identities = 120/486 (24%), Positives = 174/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 624
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 625 EVPLCA 630
Score = 68.9 bits (161), Expect = 3e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 478 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 535
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 536 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 709 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 818
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 819 --ATCQDSPQGPRCLCPTVYTGGSC 841
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 945 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 998
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 999 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1099
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1100 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1159
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1160 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1218
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1219 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1247
Score = 67.7 bits (158), Expect = 7e-10
Identities = 164/649 (25%), Positives = 221/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 529 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 576
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 577 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 632 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 687
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 688 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PT T SC A C +CL
Sbjct: 806 LRPSCADSPCRNRATCQDSPQGPRCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
Query: 574 GAQCDQCSPGY------YKYPDCLSCNCDVSGSIGSTCDDNGL---------CHCKSNFD 618
C C G+ C + S C + GL CHC F
Sbjct: 865 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 924 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 966
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 967 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1014
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1015 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 66.5 bits (155), Expect = 2e-09
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 736 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 789
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 790 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTVYTGGSCQ 842
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 843 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 954 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1004
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1063
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1064 TAGS-PLGFICHCPKGFEGPTCSHRAP 1089
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 512
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 513 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 571 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 620
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 676
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 677 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 729
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 785
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 786 PGTFSCLCAMGFQGPRC 802
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 462
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 463 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 513
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 571
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 572 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 750 GYYCTCPPSHTGPQCQTSTD 769
Score = 54.0 bits (124), Expect = 1e-05
Identities = 85/351 (24%), Positives = 120/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 715 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 764
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 765 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C Y G T + D C C N + G + CL C+
Sbjct: 824 SPQGPRC-LCPTVYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 874
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 934
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 993
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 830 CLCPTVYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 868
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 869 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 928 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 984 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1042
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1043 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1095 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1145
Query: 2074 CTD 2076
C++
Sbjct: 1146 CSE 1148
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 39.5 bits (88), Expect = 0.22
Identities = 82/346 (23%), Positives = 120/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 704
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 705 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 760
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 761 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 816
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC + G + C C + C+C G
Sbjct: 817 NRATCQDSPQGPRC-LCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 875
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 876 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 931
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 932 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 967
Score = 39.5 bits (88), Expect = 0.22
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 677 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 734
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 735 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 787
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 788 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTVYTGGS 840
Query: 1508 CDT 1510
C T
Sbjct: 841 CQT 843
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 916 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1028
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1029 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 610
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 611 FFCLCPSGFTGQLCE 625
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.8 bits (198), Expect = 1e-14
Identities = 120/486 (24%), Positives = 174/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 624
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 625 EVPLCA 630
Score = 74.1 bits (174), Expect = 9e-12
Identities = 170/649 (26%), Positives = 226/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 529 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 576
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 577 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 632 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 687
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 688 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PTG T SC A C +CL
Sbjct: 806 LRPSCADSPCRNRATCQDSPQGPRCLC-PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
Query: 574 GAQCDQCSPGY------YKYPDC----LSCNCDVSGSI--GSTCDDNG---LCHCKSNFD 618
C C G+ C LS DVS G C D+G CHC F
Sbjct: 865 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 924 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 966
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 967 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1014
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1015 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Score = 69.3 bits (162), Expect = 2e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 478 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 535
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 536 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 648
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 709 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 818
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 819 --ATCQDSPQGPRCLCPTGYTGGSC 841
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 945 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 998
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 999 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1099
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1100 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1159
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1160 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1218
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1219 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1247
Score = 67.7 bits (158), Expect = 7e-10
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 736 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 789
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 790 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGSCQ 842
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 843 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 954 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1004
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1063
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1064 TAGS-PLGFICHCPKGFEGPTCSHRAP 1089
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 512
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 513 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 571 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 620
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 676
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 677 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 729
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 785
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 786 PGTFSCLCAMGFQGPRC 802
Score = 57.6 bits (133), Expect = 8e-07
Identities = 86/351 (24%), Positives = 121/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 715 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 764
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 765 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C GY G T + D C C N + G + CL C+
Sbjct: 824 SPQGPRC-LCPTGYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 874
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 934
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 993
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 462
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 463 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 513
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 571
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 572 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 750 GYYCTCPPSHTGPQCQTSTD 769
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 830 CLCPTGYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 868
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 869 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 928 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 984 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1042
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1043 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1094
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1095 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1145
Query: 2074 CTD 2076
C++
Sbjct: 1146 CSE 1148
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 43.2 bits (97), Expect = 0.018
Identities = 83/346 (23%), Positives = 121/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 704
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 705 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 760
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 761 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 816
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC G+ G + C C + C+C G
Sbjct: 817 NRATCQDSPQGPRC-LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 875
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 876 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 931
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 932 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 967
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 40.7 bits (91), Expect = 0.097
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 677 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 734
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 735 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 787
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 788 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGS 840
Query: 1508 CDT 1510
C T
Sbjct: 841 CQT 843
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 916 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1028
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1029 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 610
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 611 FFCLCPSGFTGQLCE 625
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 83.4 bits (197), Expect = 1e-14
Identities = 92/356 (25%), Positives = 133/356 (37%), Gaps = 68/356 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C DG+ ECK C ++ + + G+C C + GR C++C YP C +
Sbjct: 215 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDEC----VPYPGCVHGS 270
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C EP QC C+ +GG CD+ L+ G C G T
Sbjct: 271 C----VEP-------WQCNCETNWGGLLCDKDLN-----YCGSHHPCT------NGGTCI 308
Query: 559 SCSADG-KCNCLTNFGGAQCDQ---------CSPG--YYKYPDCLSCNCDVSGSIGSTCD 606
+ D +C C + G C++ C+ G ++ P C+C SG G TC
Sbjct: 309 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP-SGWSGPTCA 367
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA----GCGSVPAGELCQ 662
+ C SN A TC +Q + EC C + V A+ C P
Sbjct: 368 SADIDECASN-PCAAGGTCVDQVDGF----ECICPEQWVGATCQLDANECEGKPCLNAFS 422
Query: 663 CKDRVQGRICNDCKPLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVG 721
CK+ + G C DC P + + N C + C GT L QCVC + G
Sbjct: 423 CKNLIGGYYC-DCIPGWKGINCHINVNDC-RGQCQHGGTCKDL----VNGYQCVCPRGFG 476
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R C+ L+ ++ C C GG ++ D CHC G C+
Sbjct: 477 GRHCE--------LERDE---CASSPCHSGGLCEDLADGF--HCHCPQGFSGPLCE 519
Score = 75.4 bits (177), Expect = 4e-12
Identities = 138/550 (25%), Positives = 192/550 (34%), Gaps = 100/550 (18%)
Query: 255 RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLD 314
RC N CNK C + + D++ + C EC + ++ +L
Sbjct: 181 RCDENYYSATCNKFCR--PRNDFFGHYTCDQYGNKACMDGWMGKECK--EAVCKQGCNL- 235
Query: 315 INGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEE 374
++G G+C C + +G C++C P +G +P QC NCE
Sbjct: 236 LHGGCTVPGEC-RCSYGWQGRFCDECVPYPGCVHGS------CVEPWQC-------NCET 281
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGK 434
G C D + C + PCT NG + P C C Y+G+
Sbjct: 282 NWGGLLC-----DKDLNYCGSHH-------PCT---NGGTCINAEPDQYRCTCPDGYSGR 326
Query: 435 SCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT 493
+CE E S C N C+ V S +C C S +SG TC +
Sbjct: 327 NCEKAEHACTSNPCANGGSCHEVPS--------GFECHCPSGWSGPTCASA-----DIDE 373
Query: 494 CKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCD---------QCLSGYYMQVL--GR 541
C C GT D V G +CIC + G C CL+ + + L G
Sbjct: 374 CASNPCAAGGT---CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGY 430
Query: 542 ERQCVP----CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY------YKYPDC 590
C+P NC C G C L N G QC C G+ + +C
Sbjct: 431 YCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVN--GYQC-VCPRGFGGRHCELERDEC 487
Query: 591 LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA 650
S C SG + D CHC F G C+ + CE C + A
Sbjct: 488 ASSPCH-SGGLCEDLADGFHCHCPQGFSGPLCEV------DVDLCEPSPC------RNGA 534
Query: 651 GCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGC-EQCNCNLAGTLNSLGACN 708
C ++ C C D G+ C+ +P GC + GT S G C
Sbjct: 535 RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVID-GCGSDAGPGMPGTAAS-GVCG 592
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G+CV Q G C C GF ++ + C C GG+ + D +C C
Sbjct: 593 -PHGRCV-SQPGGNFSC-ICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD--AFRCFC 647
Query: 768 HSRVEGRRCD 777
S EG CD
Sbjct: 648 PSGWEGELCD 657
Score = 67.3 bits (157), Expect = 1e-09
Identities = 113/461 (24%), Positives = 160/461 (34%), Gaps = 89/461 (19%)
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D G+ + GG C + G C C R +G R EL+ + C P S G CE
Sbjct: 449 DCRGQCQHGGTCKDL---VNGYQC-VCP----RGFGGRHCELERDE-CASSPCHSGGLCE 499
Query: 374 E--ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDG--LCPCKY 429
+ + C C F P C D C+P C G C +G C C
Sbjct: 500 DLADGFHCHCPQGFSGPLCE------VDVDLCEPSPCR----NGARCYNLEGDYYCACPD 549
Query: 430 NYAGKSCEICEDGYYSPECKNCE-CNTVGSVSYVCDKLTGDC----TCKSKYSGRTCNQC 484
++ GK+C + + C+ + C + +G C C S+ G C
Sbjct: 550 DFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC 609
Query: 485 QAGYY------NYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQ 537
+G+ N C C GT D+V +C C +G+ G CD
Sbjct: 610 DSGFTGTYCHENIDDCLGQPCRNGGT---CIDEVDAFRCFCPSGWEGELCDT-------- 658
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDV 597
C+P DP C + G+C L N CD G + C+
Sbjct: 659 ---NPNDCLP---DP-------CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA-Y 704
Query: 598 SGSIGSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ S G TC D+G C C + G+ C + +C C G C
Sbjct: 705 TCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS-----SCLPNPCVNGGT------CVG 753
Query: 655 VPAGELCQCKDRVQGRIC----NDCKPL-YWN----LQEYNPFGCEQCNCNLAGTLNSLG 705
A C C+D +GR C NDC PL +N + N F CE C AG +
Sbjct: 754 SGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRIN 812
Query: 706 ACNTKSGQC----VCKQHVGERQCDQCLDGFYRLQTNDVFG 742
+S C C + +C C G + +V G
Sbjct: 813 IDECQSSPCAYGATCVDEINGYRC-SCPPGRAGPRCQEVIG 852
Score = 66.9 bits (156), Expect = 1e-09
Identities = 92/339 (27%), Positives = 129/339 (38%), Gaps = 67/339 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCV-PCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
EC+C ++G C++C + G CV P QCN C+ N G L D N G H
Sbjct: 245 ECRCSYGWQGRFCDECVP-YPGCVHGSCVEPWQCN-----CETNWGGLLCDKDLNYCGSH 298
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C +G + D C CP Y N C+ +E+ +C P G C
Sbjct: 299 -HPCT---NGGTCINAEPDQYRCTCPDGYSGRN----CEKAEH----ACTSNPCANGGSC 346
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNC-SGNINPQDPGSCDSINGDCLKCVNN--TAGAA 1909
+G+ C+C SG P +C S + D +C +N AG
Sbjct: 347 HEVPSGF----------------ECHCPSGWSGP----TCASADID--ECASNPCAAGGT 384
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDS--TTGTCVCRPGVIGEKCDRCAPDHWG 1967
C GF + I + C + +C+ C+ + G CD C P G
Sbjct: 385 CVDQVDGF--ECICPEQWVGATC-QLDANECEGKPCLNAFSCKNLIGGYYCD-CIPGWKG 440
Query: 1968 LNTGLGCTPCNCGIASESTQCDD-DNG-QCRCAKGVTGKQC----DQCAA------GFWN 2015
+N + C G C D NG QC C +G G+ C D+CA+ G
Sbjct: 441 INCHINVNDCR-GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCE 499
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKC 2053
DG HC+C G+S G +C CE P G +C
Sbjct: 500 DLADGF-HCHCPQGFS-GPLCEVDVDLCEPSPCRNGARC 536
Score = 66.1 bits (154), Expect = 2e-09
Identities = 136/568 (23%), Positives = 196/568 (34%), Gaps = 126/568 (22%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC + G C++C + W CNC + D +++
Sbjct: 246 CRCSYGWQGRFCDECVPYPGCVHGSCVEPWQ------CNCETNWGGLLCDKDLN----YC 295
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
+ GG C+N + + C P Y G+ ++ + C +P + G+C
Sbjct: 296 GSHHPCTNGGTCINAEPDQYRCTC----PDGYS--GRNCEKAE--HACTSNPCANGGSCH 347
Query: 374 E-ESG-RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT-PTDGL-CPCKY 429
E SG C C + P C+S D C C GT C DG C C
Sbjct: 348 EVPSGFECHCPSGWSGPTCASA-----DIDECASNPCAAGGT----CVDQVDGFECICPE 398
Query: 430 NYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCKSKYSGRTCNQCQAG 487
+ G +C++ + EC+ C ++ C L G C C + G C
Sbjct: 399 QWVGATCQLDAN-----ECEGKPCLN----AFSCKNLIGGYYCDCIPGWKGINC------ 443
Query: 488 YYNYPTCKPCNCDTSGTEPSICDD-VSG-QCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
+ N C+ C GT C D V+G QC+C GFGG C+ L R+ +C
Sbjct: 444 HINVNDCRG-QCQHGGT----CKDLVNGYQCVCPRGFGGRHCE----------LERD-EC 487
Query: 546 VPCNCDPTGSTSTSCSADG-KCNCLTNFGGAQC----DQCSPGYYKYPDCLSCNCDVSGS 600
C G ADG C+C F G C D C P C +G+
Sbjct: 488 ASSPCHSGGLCED--LADGFHCHCPQGFSGPLCEVDVDLCEPS--------PCR---NGA 534
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC---EECNCD---------PRGVTAS 648
+ + C C +F G C RE AC + C D GV
Sbjct: 535 RCYNLEGDYYCACPDDFGGKNCSVPREPCPG-GACRVIDGCGSDAGPGMPGTAASGVCGP 593
Query: 649 FAGCGSVPAGEL-CQCKDRVQGRICND---------CKPLYWNLQEYNPFGCEQCNCNLA 698
C S P G C C G C++ C+ + E + F C C
Sbjct: 594 HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRC-FCPSGWE 652
Query: 699 GTLNSLGACNTKSGQCV---------CKQHVGERQCDQCLDGFY-RLQTNDVFGCTECDC 748
G L C+T C+ C V + C C DG+ + + F C C
Sbjct: 653 GEL-----CDTNPNDCLPDPCHSRGRCYDLVNDFYC-ACDDGWKGKTCHSREFQCDAYTC 706
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
GG+ ++ D T +C C +G C
Sbjct: 707 SNGGTCYDSGD--TFRCACPPGWKGSTC 732
Score = 61.7 bits (143), Expect = 5e-08
Identities = 100/375 (26%), Positives = 128/375 (34%), Gaps = 67/375 (17%)
Query: 1734 EECQCPRAYRGLSCEQCAEG-HYRLPSGFCVPCQCNGHSDQCDVNTGICLNCAD--NTIG 1790
+EC + G CE A+G H P GF P C D C+ + C N A N G
Sbjct: 485 DECASSPCHSGGLCEDLADGFHCHCPQGFSGPL-CEVDVDLCEPSP--CRNGARCYNLEG 541
Query: 1791 DHCEFCMSGYHGDATVGTPRD-CLICACPM----------PYPSNNFALSCD-----LSE 1834
D+ C + G PR+ C AC + P + C +S+
Sbjct: 542 DYYCACPDDF-GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ 600
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGD----YCKPCNCSGNI---N 1884
G SC C G+ G C G P T + D +C P G + N
Sbjct: 601 PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTN 659
Query: 1885 PQD--PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADC 1940
P D P C S G C VN+ A C G+ G S+ C A C G
Sbjct: 660 PNDCLPDPCHS-RGRCYDLVNDFYCA----CDDGWKGKTCHSREFQCDAYTCSNGGTCYD 714
Query: 1941 DSTTGTCVCRPGVIGEKC-----DRCAPD---HWGLNTGLGCT-PCNCGIASESTQCDDD 1991
T C C PG G C C P+ + G G G + C C E C +
Sbjct: 715 SGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN 774
Query: 1992 NGQCR---------CAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNA 2038
C C GV +C+ CA GF D C C G + N
Sbjct: 775 TNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEING 833
Query: 2039 TGQCECLPGVIGEKC 2053
+C C PG G +C
Sbjct: 834 Y-RCSCPPGRAGPRC 847
Score = 49.2 bits (112), Expect = 3e-04
Identities = 64/242 (26%), Positives = 88/242 (36%), Gaps = 45/242 (18%)
Query: 1784 CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C D C FC SG+ G+ P DCL P P ++ DL + C C
Sbjct: 636 CIDEVDAFRC-FCPSGWEGELCDTNPNDCL------PDPCHSRGRCYDLVND---FYCAC 685
Query: 1844 QPGYGGARC---EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI--NGDC 1898
G+ G C E+ Y T +GD + C C P GS ++ N C
Sbjct: 686 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR-CACP----PGWKGSTCAVAKNSSC 740
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTC---------V 1948
L N C G G + S +CIC D + C T C +
Sbjct: 741 LP----------NPCVNG--GTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 788
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC-DDDNG-QCRCAKGVTGKQC 2006
C GV +C+ CAP G + + C + C D+ NG +C C G G +C
Sbjct: 789 CVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 847
Query: 2007 DQ 2008
+
Sbjct: 848 QE 849
Score = 43.2 bits (97), Expect = 0.018
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 34/193 (17%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC--SACRTGYYG 1379
C E +S T N RP DF G C+ +G + C +G+ C + C+ G
Sbjct: 182 CDENYYSATC--NKFCRP-RNDFFG--HYTCDQYGNKA-CMDGWMGKECKEAVCKQG--- 232
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
C H C G C C +G CD C PY GC +C V
Sbjct: 233 ---CNLLH----GGCTVPGECRCSYGWQGRFCDECVPYP-------GCVHGSC----VEP 274
Query: 1440 NQLQCEADSGKCACRENVRGRVCDH-CVPGH---YAFPDCYQCTCNRHGTTYDVCDQNTA 1495
Q CE + G C +++ H C G A PD Y+CTC G + C++
Sbjct: 275 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEH 333
Query: 1496 QCYCKTNVRGQAC 1508
C G +C
Sbjct: 334 ACTSNPCANGGSC 346
Score = 42.7 bits (96), Expect = 0.024
Identities = 43/158 (27%), Positives = 55/158 (34%), Gaps = 28/158 (17%)
Query: 1383 CRPCHCPSTAIC---DDNGMCICPKNVEGENC----DRCKPYTFNFDVQRGCDDCNCNP- 1434
C P C + A C + + C CP + G+NC + C G D P
Sbjct: 525 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPG 584
Query: 1435 ---LGVVGNQLQCEADSG---KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD 1488
GV G +C + G C C G C H DC C GT D
Sbjct: 585 TAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC------HENIDDCLGQPCRNGGTCID 638
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
D +C+C + G+ CDT N D PD C
Sbjct: 639 EVD--AFRCFCPSGWEGELCDT------NPNDCLPDPC 668
Score = 39.5 bits (88), Expect = 0.22
Identities = 84/339 (24%), Positives = 112/339 (33%), Gaps = 57/339 (16%)
Query: 1730 ATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNC--ADN 1787
+ ++EC G +C +G + V C +++C+ CLN N
Sbjct: 368 SADIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKN 425
Query: 1788 TIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
IG + C+ G+ G DC C +C NG C C G+
Sbjct: 426 LIGGYYCDCIPGWKGINCHINVNDCR-GQC-------QHGGTCKDLVNG--YQCVCPRGF 475
Query: 1848 GGARCEY----CAAG---YYGIPEDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCL 1899
GG CE CA+ G+ E DL G +C P SG + D C+
Sbjct: 476 GGRHCELERDECASSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEP-----S 528
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTCVCRPGVIGEKC 1958
C N GA C +Y C C D+FG +C C PG
Sbjct: 529 PCRN---GARCYNLEGDYY-----------CACPDDFGGKNCSVPREPC---PGGACRVI 571
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
D C D G + CG N C C G TG C +
Sbjct: 572 DGCGSDAGPGMPGTAASGV-CGPHGRCVSQPGGNFSCICDSGFTGTYCHE--------NI 622
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
D C C G + +A +C C G GE CD P
Sbjct: 623 DDCLGQPCRNGGTCIDEVDAF-RCFCPSGWEGELCDTNP 660
Score = 38.3 bits (85), Expect = 0.52
Identities = 41/150 (27%), Positives = 48/150 (32%), Gaps = 14/150 (9%)
Query: 1920 DAIFSKNCTACICDE---FGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP 1976
D K C +C + C + G C C G G CD C P + G G P
Sbjct: 217 DGWMGKECKEAVCKQGCNLLHGGC-TVPGECRCSYGWQGRFCDECVP-YPGCVHGSCVEP 274
Query: 1977 --CNCGIASESTQCDDDNGQCRCAKGVT-GKQCDQCAAGFWNYT-KDGCDHCNCNTG--Y 2030
CNC CD D C T G C + T DG NC
Sbjct: 275 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 334
Query: 2031 SVGFMCNATGQCECLPGVIGEKCDRCPERW 2060
C G C +P G +C CP W
Sbjct: 335 CTSNPCANGGSCHEVPS--GFEC-HCPSGW 361
Score = 36.7 bits (81), Expect = 1.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 15/61 (24%)
Query: 1449 GKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+C C +GR CD CVP +P C HG+ + QC C+TN G C
Sbjct: 244 GECRCSYGWQGRFCDECVP----YPGCV------HGSCVE-----PWQCNCETNWGGLLC 288
Query: 1509 D 1509
D
Sbjct: 289 D 289
Score = 36.3 bits (80), Expect = 2.1
Identities = 47/190 (24%), Positives = 74/190 (38%), Gaps = 38/190 (20%)
Query: 1340 CLC--DFMGST-ELECNTFGGQCPCK-----PNVIGRTCSACRTGYYGFP---NCRPCH- 1387
C+C ++G+T +L+ N G+ PC N+IG C G+ G N C
Sbjct: 394 CICPEQWVGATCQLDANECEGK-PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG 452
Query: 1388 -CPSTAICDD--NG-MCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ 1443
C C D NG C+CP+ G +C +++R D+C +P G +
Sbjct: 453 QCQHGGTCKDLVNGYQCVCPRGFGGRHC----------ELER--DECASSPCH-SGGLCE 499
Query: 1444 CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
AD C C + G +C+ V C C Y++ + C C +
Sbjct: 500 DLADGFHCHCPQGFSGPLCEVDV------DLCEPSPCRNGARCYNL--EGDYYCACPDDF 551
Query: 1504 RGQACDTCKE 1513
G+ C +E
Sbjct: 552 GGKNCSVPRE 561
Score = 35.9 bits (79), Expect = 2.8
Identities = 39/153 (25%), Positives = 46/153 (30%), Gaps = 29/153 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG---MCICPKNVEGENCDRCK 1415
C C G+TC + C C + C D+G C CP +G C K
Sbjct: 683 CACDDGWKGKTCHSREF------QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 736
Query: 1416 PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDC 1475
C NP V G S C CR+ GR C H DC
Sbjct: 737 N-----------SSCLPNPC-VNGGTCVGSGASFSCICRDGWEGRTCTHNT------NDC 778
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C G D N +C C G C
Sbjct: 779 NPLPCYNGGICVD--GVNWFRCECAPGFAGPDC 809
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 83.0 bits (196), Expect = 2e-14
Identities = 153/585 (26%), Positives = 203/585 (34%), Gaps = 99/585 (16%)
Query: 233 CNGHADTCEPADPAGNLNILVCRCQHNTCGPQCN---KCCSGFEQKKWRISQNWD-RFSC 288
C G C+ + AG CRC GP C+ C S R S D RF C
Sbjct: 90 CAGRG-VCQSSVVAGTARFS-CRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLC 147
Query: 289 EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINCNK- 339
C C D +DE R + GG CLN C G C
Sbjct: 148 S-CPPGYQGRSCRSD--VDECR----VGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 200
Query: 340 ---CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYG 396
C P+ R G D+ C C P F NCE C P + + +C G
Sbjct: 201 AVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC---PGHRCLNGGTCVDG 257
Query: 397 YFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN--YAGKSCEICEDGYYSPECKNCECN 454
Y NC+ C T G+ CT C + N + G +C G+ +C C
Sbjct: 258 VNTY-NCQ---CPPEWT-GQFCTEDVDECQLQPNACHNGGTCFNTLGGH------SCVC- 305
Query: 455 TVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYY-NYPTCKP---CNCDTSGT-----E 505
G C + DC + G TC+ A +Y P K C+ D + E
Sbjct: 306 VNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHE 365
Query: 506 PSICD--DVSGQ--CICKAGFGGPRCDQ----CLSGYY-MQVLGR---ERQCVPCNCDPT 553
+ICD V+G+ C C GF G CDQ C G + LGR + C C
Sbjct: 366 DAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG-R 424
Query: 554 GSTSTSCSAD------GKC----NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
G T C D G C CL G C C G+ C D+ S
Sbjct: 425 GYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC-ICMAGF----TGTYCEVDIDECQSS 479
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGEL 660
C + G+ CK +G C TC F +EC P + A C P G
Sbjct: 480 PCVNGGV--CKDRVNGFSC-TCPSGFSGSTCQLDVDECASTP---CRNGAKCVDQPDGYE 533
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
C+C + +G +C+ N+ + +P C C + G + AC C+ V
Sbjct: 534 CRCAEGFEGTLCDR------NVDDCSPDPCHHGRC-VDGIASFSCACAPGYTGTRCESQV 586
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
E + C G L D + C C G+ NC+ C
Sbjct: 587 DECRSQPCRHGGKCLDLVDKYLC-RCP---SGTTGVNCEVNIDDC 627
Score = 74.1 bits (174), Expect = 9e-12
Identities = 119/479 (24%), Positives = 172/479 (35%), Gaps = 82/479 (17%)
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGR----YEGGGKCLNCQHNTEGINCNK 339
DR + C C + + T ++DE + NG G +C C EG C++
Sbjct: 489 DRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGFEGTLCDR 547
Query: 340 ----CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAY 395
C P +G+ D + C C P ++ CE + C +P C
Sbjct: 548 NVDDCSPDPCH-HGRCVDGI-ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVD 605
Query: 396 GYFDYPNCKPCTCNLNGTEGEHCTPTDGLC---PCKYNYAGKSCE----ICEDGYYSPEC 448
Y C C +GT G +C C PC + +C+ G+ P C
Sbjct: 606 KYL-------CRCP-SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLC 657
Query: 449 KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN--CDTSGTEP 506
N E N S C + +C +G C C G P C P + C
Sbjct: 658 -NVEINECASSP--CGE---GGSCVDGENGFRC-LCPPGSLP-PLCLPPSHPCAHEPCSH 709
Query: 507 SICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
IC D G +C+C+ G+ GPRC Q L+ R+ C P + T CS+DG
Sbjct: 710 GICYDAPGGFRCVCEPGWSGPRCSQSLA--------RD----ACESQPCRAGGT-CSSDG 756
Query: 565 ---KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAK 621
C C G QC+ SP C C+ G S +C C +
Sbjct: 757 MGFHCTCPPGVQGRQCELLSP-------CTPNPCEHGGRCESAPGQLPVCSCPQGWQDPC 809
Query: 622 CD--TCREQFYNYP-ACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
+ +C++ ++ +C PR C S P G C D V C C P
Sbjct: 810 LNGGSCQDGVGSFSCSCLPGFAGPR-CARDVDECLSNPCGP-GTCTDHVASFTCT-CPP- 865
Query: 679 YWNLQEYNPFGCEQ--CNCNLAGTLNSLGAC--NTKSGQCVCKQ-HVG---ERQCDQCL 729
Y F CEQ +C+ + N G C S C+C+ + G + + D CL
Sbjct: 866 -----GYGGFHCEQDLPDCSPSSCFNG-GTCVDGVNSFSCLCRPGYTGAHCQHEADPCL 918
Score = 68.9 bits (161), Expect = 3e-10
Identities = 93/370 (25%), Positives = 127/370 (34%), Gaps = 60/370 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVP------CQC---------NGHSDQCDV 1776
+C C + G +CE + GH L G CV CQC D+C +
Sbjct: 224 DCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQL 283
Query: 1777 NTGICLNCAD--NTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSN----NFALSC 1830
C N NT+G H C++G+ G++ DC C + +F +C
Sbjct: 284 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 343
Query: 1831 DLSENGSLI----SCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP--CNCSGNIN 1884
+ + G L +C P + A C+ I TG C CS N
Sbjct: 344 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 403
Query: 1885 P-QDPGSCDSINGDCL-KCVNNTAGAAC----NLCAPG---FYGDAIFSKNCTACIC-DE 1934
P + G C + G L +C G C N C G + CIC
Sbjct: 404 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAG 463
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKC-DR-------CAPDHWGLNTGLGCTPCNCGIASEST 1986
F C+ C P V G C DR C G L C
Sbjct: 464 FTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGA 523
Query: 1987 QCDD--DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCEC 2044
+C D D +CRCA+G G CD+ + + D C H C G A+ C C
Sbjct: 524 KCVDQPDGYECRCAEGFEGTLCDR---NVDDCSPDPCHHGRCVDGI-------ASFSCAC 573
Query: 2045 LPGVIGEKCD 2054
PG G +C+
Sbjct: 574 APGYTGTRCE 583
Score = 68.9 bits (161), Expect = 3e-10
Identities = 92/342 (26%), Positives = 122/342 (35%), Gaps = 61/342 (17%)
Query: 1733 VEECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ECQ G C+ G PSGF C D+C C N C D
Sbjct: 473 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFS-GSTCQLDVDECASTP--CRNGAKCVDQP 529
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C C G+ G DC P P ++ ++ SC C PGY
Sbjct: 530 DGYECR-CAEGFEGTLCDRNVDDC------SPDPCHHGRCVDGIAS----FSCACAPGYT 578
Query: 1849 GARCEYCAAGYYGIP-----EDTDLHTGDYCK-PCNCSG---NINPQDPGSCDSINGDCL 1899
G RCE P + DL C+ P +G +N D S G C
Sbjct: 579 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 638
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEK 1957
+N C +C PGF G + C + C E G C+C PG +
Sbjct: 639 DGINR---YDC-VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPL 694
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG--QCRCAKGVTGKQCDQCAAGFWN 2015
C P H PC+ GI C D G +C C G +G +C Q A
Sbjct: 695 C--LPPSH-----PCAHEPCSHGI------CYDAPGGFRCVCEPGWSGPRCSQSLA---- 737
Query: 2016 YTKDGCDHCNCNTGYSVGFMCNATG---QCECLPGVIGEKCD 2054
+D C+ C G + C++ G C C PGV G +C+
Sbjct: 738 --RDACESQPCRAGGT----CSSDGMGFHCTCPPGVQGRQCE 773
Score = 68.1 bits (159), Expect = 6e-10
Identities = 73/270 (27%), Positives = 90/270 (33%), Gaps = 39/270 (14%)
Query: 360 PCQCDPHFSTGNCEEESG--RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEH 417
PC P G C G CEC P + +C D C C G+ +
Sbjct: 1038 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED------DVDECASQPCQHGGSCIDL 1091
Query: 418 CTPTDGLCPCKYNYAGKSCEICED--GYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
LC C G CEI ED G P C G+ C L G CTC
Sbjct: 1092 VARY--LCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT----CVDLVGGFRCTCP 1145
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLS 532
Y+G C + C+ C + T + D G +C+C AGF GPRC LS
Sbjct: 1146 PGYTGLRCEA------DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLS 1199
Query: 533 GYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Q QC P G T T C+C F G +C++ + C
Sbjct: 1200 PCESQPCQHGGQCRPSPGPGGGLTFT-------CHCAQPFWGPRCERVA------RSCRE 1246
Query: 593 CNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
C V T C C G C
Sbjct: 1247 LQCPVGVPCQQT-PRGPRCACPPGLSGPSC 1275
Score = 60.5 bits (140), Expect = 1e-07
Identities = 121/485 (24%), Positives = 163/485 (33%), Gaps = 77/485 (15%)
Query: 325 CLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE--SGRC 379
CLN CQ +C+ C P + P R ++D C C P G C + S C
Sbjct: 809 CLNGGSCQDGVGSFSCS-CLPGFAGPRCAR--DVDECLSNPCGP----GTCTDHVASFTC 861
Query: 380 ECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEIC 439
C P + C D P+C P +C GT + C C+ Y G C+
Sbjct: 862 TCPPGYGGFHCEQ------DLPDCSPSSCFNGGTCVDGVNSFS--CLCRPGYTGAHCQHE 913
Query: 440 EDGYYSPECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
D S C + C G + TG C++ + CQ G T
Sbjct: 914 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGP-QCQTLVDWCSRQPCQNGGRCVQTGAY 972
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ-CLSGYYMQVLGRERQCVPCNCDPTGS 555
C C G +CD S C A G R +Q C +G CV C P G
Sbjct: 973 CLCPP-GWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV---C-PEGR 1027
Query: 556 TSTSCSAD-GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDN-GLCHC 613
T + C + C G C GY C C + G G C+D+ C
Sbjct: 1028 TGSHCEQEVDPCLAQPCQHGGTCRGYMGGYM-------CEC-LPGYNGDNCEDDVDECAS 1079
Query: 614 KSNFDGAKCDTCREQFYNYPACEECNCDPR--GVTASFA--GCGSVP---AGELC----Q 662
+ G C ++ C+C P GV CG P +G C
Sbjct: 1080 QPCQHGGSCIDLVARYL-------CSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT 1132
Query: 663 CKDRVQGRICNDCKPLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSG-QCVCKQHV 720
C D V G C C P Y L+ E + C C+ A T + L + G +C+C
Sbjct: 1133 CVDLVGGFRCT-CPPGYTGLRCEADINECRSGACHAAHTRDCLQ--DPGGGFRCLCHAGF 1189
Query: 721 GERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG---QCHCHSRVEGRRCD 777
+C L C C GG + G CHC G RC+
Sbjct: 1190 SGPRCQTVLSP-----------CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1238
Query: 778 QPIRA 782
+ R+
Sbjct: 1239 RVARS 1243
Score = 60.1 bits (139), Expect = 1e-07
Identities = 90/340 (26%), Positives = 113/340 (33%), Gaps = 72/340 (21%)
Query: 1758 PSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHC----EFCMSGYHGDATVGTPRDCL 1813
P G+ PC NG S Q V + C +C G C + C+S G T
Sbjct: 802 PQGWQDPC-LNGGSCQDGVGSFSC-SCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASF 859
Query: 1814 ICACPMPYPSNNFALSCDLSE-------NGSL-------ISCNCQPGYGGARCEYCAAGY 1859
C CP Y F DL + NG SC C+PGY GA C+
Sbjct: 860 TCTCPPGY--GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ------ 911
Query: 1860 YGIPEDTDLHTGDYC--KPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGF 1917
H D C +PC G + PG C C+ + G C
Sbjct: 912 ---------HEADPCLSRPCLHGGVCSAAHPGF------RC-TCLESFTGPQCQTLVDW- 954
Query: 1918 YGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCD-RCAPDHWGLNTGLGCTP 1976
C+ C G C T C+C PG G CD R P +G
Sbjct: 955 ---------CSRQPCQNGGR--CVQTGAYCLCPPGWSGRLCDIRSLPCREAA-AQIGVRL 1002
Query: 1977 CNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMC 2036
A +D + C C +G TG C+Q C H GY G+M
Sbjct: 1003 EQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVD---PCLAQPCQHGGTCRGYMGGYM- 1058
Query: 2037 NATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTD 2076
CECLPG G+ C+ + P C SC D
Sbjct: 1059 -----CECLPGYNGDNCEDDVDECASQP---CQHGGSCID 1090
Score = 58.4 bits (135), Expect = 5e-07
Identities = 92/360 (25%), Positives = 126/360 (35%), Gaps = 77/360 (21%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG--ICLNCADNTIGDHC 1793
C+CPR +RG C LP C+ C H +C V +C G C
Sbjct: 109 CRCPRGFRGPDCS--------LPDP-CLSSPC-AHGARCSVGPDGRFLCSCPPGYQGRSC 158
Query: 1794 ----EFCMSG---YHGDATVGTPRDCLICACPMPYPS---NNFALSCDLS---------E 1834
+ C G HG + TP C CP Y N A+ C S +
Sbjct: 159 RSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQ 217
Query: 1835 NGSL-ISCNCQPGYGGARCEY---CAAGYYGIPEDT---DLHTGDYCKPCNCSGNINPQD 1887
+G L C C PG+ G CE G+ + T ++T + P +G +D
Sbjct: 218 SGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTED 277
Query: 1888 PGSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDS 1942
C C C N G +C +C G+ G++ +C +C F A C
Sbjct: 278 VDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCSQNIDDCATAVC--FHGATCHD 334
Query: 1943 TTGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CR 1996
+ C C G G C L+ PC+ E CD + NG+ C
Sbjct: 335 RVASFYCACPMGKTGLLCH--------LDDACVSNPCH-----EDAICDTNPVNGRAICT 381
Query: 1997 CAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCD 2054
C G TG CDQ D C N +G N G C+C G G +C+
Sbjct: 382 CPPGFTGGACDQ--------DVDECS-IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE 432
Score = 56.8 bits (131), Expect = 1e-06
Identities = 89/365 (24%), Positives = 127/365 (34%), Gaps = 67/365 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC+C + G C++ + C P C+ H D CA G CE
Sbjct: 533 ECRCAEGFEGTLCDRNVDD--------CSPDPCH-HGRCVDGIASFSCACAPGYTGTRCE 583
Query: 1795 F----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCD----------LSENG-S 1837
C S HG + D +C CP N ++ D + +G +
Sbjct: 584 SQVDECRSQPCRHGGKCLDLV-DKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGIN 642
Query: 1838 LISCNCQPGYGGARCEY----CAAGYYGIPEDTDLHTGDYCKPCNCS-GNINPQD-PGSC 1891
C CQPG+ G C CA+ G E G+ C C G++ P P S
Sbjct: 643 RYDCVCQPGFTGPLCNVEINECASSPCG--EGGSCVDGENGFRCLCPPGSLPPLCLPPSH 700
Query: 1892 DSINGDCLK--CVNNTAGAACNLCAPGFYG----DAIFSKNCTACICDEFGMADCDSTTG 1945
+ C C + G C +C PG+ G ++ C + C G D
Sbjct: 701 PCAHEPCSHGICYDAPGGFRC-VCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF 759
Query: 1946 TCVCRPGVIGEKCDRCAP------DHWG-LNTGLGCTP-CNCGIASEST-----QCDDDN 1992
C C PGV G +C+ +P +H G + G P C+C + C D
Sbjct: 760 HCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQDGV 819
Query: 1993 G--QCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
G C C G G +C + D C C G + + T C C PG G
Sbjct: 820 GSFSCSCLPGFAGPRCAR--------DVDECLSNPCGPGTCTDHVASFT--CTCPPGYGG 869
Query: 2051 EKCDR 2055
C++
Sbjct: 870 FHCEQ 874
Score = 52.0 bits (119), Expect = 4e-05
Identities = 97/376 (25%), Positives = 131/376 (34%), Gaps = 66/376 (17%)
Query: 1736 CQCPRAYRGLSCEQ----CAE------GHYRLPSGFCVPCQC-NGHSDQ-CDVNTGIC-- 1781
CQCP Y G CE CA G R C C G Q C+VN C
Sbjct: 186 CQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPG 245
Query: 1782 ---LN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
LN C D +C+ C + G +C + P +N +C +
Sbjct: 246 HRCLNGGTCVDGVNTYNCQ-CPPEWTGQFCTEDVDECQL----QPNACHNGG-TCFNTLG 299
Query: 1836 GSLISCNCQPGYGGARCEY----CAAG--YYGIPEDTDLHTGDYCK-PCNCSGNINPQDP 1888
G SC C G+ G C CA ++G D YC P +G + D
Sbjct: 300 GH--SCVCVNGWTGESCSQNIDDCATAVCFHGATCH-DRVASFYCACPMGKTGLLCHLDD 356
Query: 1889 GSCDS-INGDCLKCVNNTAGAACNLCAPGFYGDAIFSK--NCT--ACICDEFGMADCDST 1943
+ + D + N G A C PGF G A C+ A C+ G C +T
Sbjct: 357 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGR--CVNT 414
Query: 1944 TGT--CVCRPGVIGEKCDR---------CAPDHWGLNTGLGCTPCNCGIASESTQCDDDN 1992
G+ C C G G +C+ C L+ +G C C T C+ D
Sbjct: 415 QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDR-IGQFTCICMAGFTGTYCEVDI 473
Query: 1993 GQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGE 2051
+C+ + V G C GF C C +G+S G C +C P G
Sbjct: 474 DECQSSPCVNGGVCKDRVNGF---------SCTCPSGFS-GSTCQLDVDECASTPCRNGA 523
Query: 2052 KCDRCPERWVLIPQEG 2067
KC P+ + EG
Sbjct: 524 KCVDQPDGYECRCAEG 539
Score = 49.2 bits (112), Expect = 3e-04
Identities = 69/258 (26%), Positives = 88/258 (34%), Gaps = 49/258 (18%)
Query: 424 LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGS-VSYVCDKLTGDCTCKSKYSGRTC- 481
+C C Y G +CE D EC + C GS + V L C+C G C
Sbjct: 1058 MCECLPGYNGDNCEDDVD-----ECASQPCQHGGSCIDLVARYL---CSCPPGTLGVLCE 1109
Query: 482 -NQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICKAGFGGPRCD----QCLSGY 534
N+ G P C +GT C D+ G +C C G+ G RC+ +C SG
Sbjct: 1110 INEDDCGP-GPPLDSGPRCLHNGT----CVDLVGGFRCTCPPGYTGLRCEADINECRSGA 1164
Query: 535 YMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
R+ C DP G +C C F G +C P
Sbjct: 1165 CHAAHTRD-----CLQDPGGGF--------RCLCHAGFSGPRCQTVLSPCESQPCQHGGQ 1211
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
C S G CHC F G +C+ +C E C P GV C
Sbjct: 1212 CRPSPGPGGGLTFT--CHCAQPFWGPRCERVAR------SCRELQC-PVGVP-----CQQ 1257
Query: 655 VPAGELCQCKDRVQGRIC 672
P G C C + G C
Sbjct: 1258 TPRGPRCACPPGLSGPSC 1275
Score = 48.8 bits (111), Expect = 4e-04
Identities = 89/346 (25%), Positives = 116/346 (33%), Gaps = 63/346 (18%)
Query: 1736 CQCPRAYRGLSCE----QCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP + G C+ C E ++ CQ G D ++ C+ C + G
Sbjct: 973 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED-SSHYCV-CPEGRTGS 1030
Query: 1792 HCEF----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQP 1845
HCE C++ HG G + C C Y +N C+ + C QP
Sbjct: 1031 HCEQEVDPCLAQPCQHGGTCRGYMGGYM-CECLPGYNGDN----CE----DDVDECASQP 1081
Query: 1846 GYGGARCEYCAAGYY-GIPEDTDLHTGDYCK--PCNCSGNINPQDPGSCDSINGDCLKCV 1902
G C A Y P T G C+ +C G P D G NG C+ V
Sbjct: 1082 CQHGGSCIDLVARYLCSCPPGT---LGVLCEINEDDC-GPGPPLDSGPRCLHNGTCVDLV 1137
Query: 1903 NNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTG---TCVCRPGVIGEK 1957
G C C PG+ G + C + C DC G C+C G G +
Sbjct: 1138 G---GFRCT-CPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPR 1193
Query: 1958 CDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGK---QCDQCAAGFW 2014
C +PC ES C GQCR + G G C CA FW
Sbjct: 1194 CQTVL------------SPC------ESQPCQH-GGQCRPSPGPGGGLTFTC-HCAQPFW 1233
Query: 2015 NYTKDGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCP 2057
+ VG C T + C C PG+ G C P
Sbjct: 1234 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFP 1279
Score = 48.0 bits (109), Expect = 6e-04
Identities = 58/249 (23%), Positives = 87/249 (34%), Gaps = 27/249 (10%)
Query: 1840 SCNCQPGYGGARCEY---CAAGYY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDS 1893
+C C PG+ G RC+ C +G G+ + + + G C C D D
Sbjct: 67 ACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVV-AGTARFSCRCPRGFRGPDCSLPDP 125
Query: 1894 -INGDCL---KCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
++ C +C G C PG+ G ++C + + DE + + GTC+
Sbjct: 126 CLSSPCAHGARCSVGPDGRFLCSCPPGYQG-----RSCRSDV-DECRVGEPCRHGGTCLN 179
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
PG +C N + C P C Q D C C G G+ C+
Sbjct: 180 TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE-- 237
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCL 2069
D C C G + N T C+C P G+ C + L P C
Sbjct: 238 ------VNVDDCPGHRCLNGGTCVDGVN-TYNCQCPPEWTGQFCTEDVDECQLQP-NACH 289
Query: 2070 ECDSCTDAL 2078
+C + L
Sbjct: 290 NGGTCFNTL 298
Score = 46.8 bits (106), Expect = 0.001
Identities = 88/350 (25%), Positives = 112/350 (32%), Gaps = 65/350 (18%)
Query: 1764 PCQCNGHSDQCDVNTGICLNCADNTIGDHCEF---CMSG-------YHGDATVGTPRDCL 1813
PC G Q CL C +G+ C+ C SG GT R
Sbjct: 51 PCANGGRCTQLPSREAACL-CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSC 109
Query: 1814 ICA-------CPMPYPSNNFALS----CDLSENGSLISCNCQPGYGGARC----EYCAAG 1858
C C +P P + + C + +G + C+C PGY G C + C G
Sbjct: 110 RCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFL-CSCPPGYQGRSCRSDVDECRVG 168
Query: 1859 YYGIPEDTDLHT-GDYCKPCN-------CSGNINPQDPGSCDSINGDCLKCVNNTAGAAC 1910
T L+T G + C C P P C + G C + + T AC
Sbjct: 169 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRN-GGTCRQSGDLTYDCAC 227
Query: 1911 NLCAPGFYGD--AIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC----DRCA-- 1962
PGF G + +C C G T C C P G+ C D C
Sbjct: 228 ---LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 284
Query: 1963 PD--HWG---LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
P+ H G NT LG C C C + C A G C A F+
Sbjct: 285 PNACHNGGTCFNT-LGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 343
Query: 2018 KDG-----C---DHCNCNTGYSVGFM----CNATGQCECLPGVIGEKCDR 2055
G C D C N + N C C PG G CD+
Sbjct: 344 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ 393
Score = 45.2 bits (102), Expect = 0.005
Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 19/186 (10%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGM-CICPKNVEGENCDRC 1414
G +C C+P G CS +PC T D G C CP V+G C+
Sbjct: 718 GFRCVCEPGWSGPRCSQSLAR--DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL 775
Query: 1415 KPYTFNFDVQRG-CDDCNCN-PLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAF 1472
P T N G C+ P+ Q +G +C++ V C C+PG +A
Sbjct: 776 SPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGG-SCQDGVGSFSCS-CLPG-FAG 832
Query: 1473 PDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY--FNLQDDNPDGCTKCF 1530
P +C + + C T C +V C TC Y F+ + D PD C+
Sbjct: 833 P---RCARDVDECLSNPCGPGT----CTDHVASFTC-TCPPGYGGFHCEQDLPD-CSPSS 883
Query: 1531 CFGKTT 1536
CF T
Sbjct: 884 CFNGGT 889
Score = 44.4 bits (100), Expect = 0.008
Identities = 59/247 (23%), Positives = 84/247 (34%), Gaps = 45/247 (18%)
Query: 1336 GARPCLCDFMGSTELECNTFGGQC---PCKPNV-----IGRTCSACRTGYYG------FP 1381
G+ C C G T C T +C PC+ IG+ C G+ G
Sbjct: 416 GSFLCQCG-RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDID 474
Query: 1382 NCRPCHCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVV 1438
C+ C + +C D NG C CP G C DV D+C P
Sbjct: 475 ECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ--------LDV----DECASTPCRN- 521
Query: 1439 GNQLQCEADSGKCACRENVRGRVCDH----CVPGHYAFPDC------YQCTCNRHGTTYD 1488
G + + D +C C E G +CD C P C + C C G T
Sbjct: 522 GAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCAC-APGYTGT 580
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSYYTWAAI 1548
C+ +C + G C ++Y P G T C C+S+ T+
Sbjct: 581 RCESQVDECRSQPCRHGGKCLDLVDKYL---CRCPSGTTGVNCEVNIDDCASNPCTFGVC 637
Query: 1549 DEMVDWY 1555
+ ++ Y
Sbjct: 638 RDGINRY 644
Score = 40.3 bits (90), Expect = 0.13
Identities = 79/301 (26%), Positives = 97/301 (32%), Gaps = 59/301 (19%)
Query: 516 CICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNF 572
C+C G+ G RC D C SG GR C S+ + +A C C F
Sbjct: 68 CLCPPGWVGERCQLEDPCHSG---PCAGRG----VCQ-----SSVVAGTARFSCRCPRGF 115
Query: 573 GGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR-- 626
G C P CLS C D LC C + G C D CR
Sbjct: 116 RGPDCSLPDP-------CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 168
Query: 627 ------EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKD----RVQGRICNDCK 676
N P C C P G T +VP C++ R G + DC
Sbjct: 169 EPCRHGGTCLNTPGSFRCQC-PAGYTGPLCENPAVPCAP-SPCRNGGTCRQSGDLTYDCA 226
Query: 677 --PLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQC-------VCKQHVGERQC- 725
P + E N C C GT + NT + QC C + V E Q
Sbjct: 227 CLPGFEGQNCEVNVDDCPGHRCLNGGT--CVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 284
Query: 726 -DQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDK-TTGQCH----CHSRVEGRRCDQP 779
+ C +G T C + G S N D T C CH RV C P
Sbjct: 285 PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP 344
Query: 780 I 780
+
Sbjct: 345 M 345
Score = 39.9 bits (89), Expect = 0.17
Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 29/189 (15%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG 1398
PCL GS + +F C C P G C+ P C P C +
Sbjct: 808 PCLNG--GSCQDGVGSFS--CSCLPGFAGPRCARDVDECLSNP-CGPGTCTDHVA---SF 859
Query: 1399 MCICPKNVEGENCDR----CKPYT-FNFDV-QRGCDD--CNCNPLGVVGNQLQCEADSGK 1450
C CP G +C++ C P + FN G + C C P G G Q EAD
Sbjct: 860 TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP-GYTGAHCQHEADP-- 916
Query: 1451 CACRENVRGRVCDHCVPG-------HYAFPDCYQCT--CNRHG-TTYDVCDQNTAQCYCK 1500
C R + G VC PG + P C C+R C Q A C C
Sbjct: 917 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP 976
Query: 1501 TNVRGQACD 1509
G+ CD
Sbjct: 977 PGWSGRLCD 985
Score = 35.9 bits (79), Expect = 2.8
Identities = 52/208 (25%), Positives = 70/208 (33%), Gaps = 30/208 (14%)
Query: 1352 CNTFGGQCPCKPNVIGRTCSA----CR--TGYYGFPNCRPCHCPSTAICDDNG-MCICPK 1404
C G C C P GR C CR G + C + +D+ C+CP+
Sbjct: 966 CVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1025
Query: 1405 NVEGENCDRCKPYTFNFDVQRG--CDD------CNCNPLGVVGNQLQCEADSGKCACREN 1456
G +C++ Q G C C C P G G+ CE D +CA +
Sbjct: 1026 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLP-GYNGD--NCEDDVDECASQPC 1082
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV-RGQAC---DTCK 1512
G C V Y C+C GT +C+ N C + G C TC
Sbjct: 1083 QHGGSCIDLVAR-------YLCSC-PPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1134
Query: 1513 EEYFNLQDDNPDGCTKCFCFGKTTRCSS 1540
+ + P G T C C S
Sbjct: 1135 DLVGGFRCTCPPGYTGLRCEADINECRS 1162
Score = 34.7 bits (76), Expect = 6.4
Identities = 44/169 (26%), Positives = 55/169 (32%), Gaps = 26/169 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYY----GFPNCRPCHCPSTAICDDNGM----CICPKNVE 1407
GG C P C A TG P C P C + C +G C C E
Sbjct: 174 GGTCLNTPGSFRCQCPAGYTGPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFE 232
Query: 1408 GENC----DRCKPYTF--NFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENV--RG 1459
G+NC D C + G + NC Q C D +C + N G
Sbjct: 233 GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQF-CTEDVDECQLQPNACHNG 291
Query: 1460 RVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C + + GH C C +G T + C QN C G C
Sbjct: 292 GTCFNTLGGH-------SCVC-VNGWTGESCSQNIDDCATAVCFHGATC 332
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2005
Score = 81.8 bits (193), Expect = 4e-14
Identities = 119/486 (24%), Positives = 173/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 182 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 235
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 236 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 295
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ P +C GT C + +G C+C
Sbjct: 296 GLDTYT--CLCPETWTGWDCSE---DVDECEAQGPPHCRNGGT----CQNSAGSFHCVCV 346
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 347 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 405
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 406 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 464
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 465 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 512
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 513 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 572
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 573 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 626
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 627 EVPLCA 632
Score = 74.1 bits (174), Expect = 9e-12
Identities = 170/649 (26%), Positives = 226/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 471 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 530
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 531 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 578
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 579 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 633
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 634 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 689
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 690 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 747
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 748 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 807
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PTG T SC A C +CL
Sbjct: 808 LRPSCADSPCRNRATCQDSPQGPRCLC-PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 866
Query: 574 GAQCDQCSPGY------YKYPDC----LSCNCDVSGSI--GSTCDDNG---LCHCKSNFD 618
C C G+ C LS DVS G C D+G CHC F
Sbjct: 867 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 925
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 926 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 968
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 969 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1016
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1017 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1064
Score = 69.3 bits (162), Expect = 2e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 420 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 479
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 480 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 537
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 538 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 590
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 591 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 650
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 651 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 710
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 711 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 769
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 770 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 820
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 821 --ATCQDSPQGPRCLCPTGYTGGSC 843
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 947 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 1000
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 1001 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1054
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1055 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1101
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1102 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1161
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1162 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1220
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1221 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1249
Score = 67.7 bits (158), Expect = 7e-10
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 302 CLCPETWTGWDCSEDVD-----------ECEAQG-PPHCR-NGGTCQNSAGSF---HC-V 344
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 345 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 404
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 405 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 459
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 460 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 519
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 520 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 570
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 571 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 606
Score = 67.7 bits (158), Expect = 7e-10
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 738 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 791
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 792 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGSCQ 844
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 845 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 896
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 897 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 955
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 956 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1006
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1007 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1065
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1066 TAGS-PLGFICHCPKGFEGPTCSHRAP 1091
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 463 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 514
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 515 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 572
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 573 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 622
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 623 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 678
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 679 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 731
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 732 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 787
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 788 PGTFSCLCAMGFQGPRC 804
Score = 57.6 bits (133), Expect = 8e-07
Identities = 86/351 (24%), Positives = 121/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 717 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 766
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 767 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 825
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C GY G T + D C C N + G + CL C+
Sbjct: 826 SPQGPRC-LCPTGYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 876
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 877 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 936
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 937 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 995
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 996 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1046
Score = 56.4 bits (130), Expect = 2e-06
Identities = 88/332 (26%), Positives = 121/332 (36%), Gaps = 49/332 (14%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 54 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 112
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 113 GERCQAQLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 165
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 166 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 224
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKC----DRCAP 1963
G G + + C C G M + DST C+C PG IG C D C
Sbjct: 225 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVS 284
Query: 1964 ---DHWG-LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD 2019
+ G GL C C C +D +C A+G C G
Sbjct: 285 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE-AQGP-----PHCRNGGTCQNSA 338
Query: 2020 GCDHCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
G HC C +G+ G C C C PG
Sbjct: 339 GSFHCVCVSGWG-GTSCEENLDDCIAATCAPG 369
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 420 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 464
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 465 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 515
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 516 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 573
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 574 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 631
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 632 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 691
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 692 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 751
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 752 GYYCTCPPSHTGPQCQTSTD 771
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 832 CLCPTGYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 870
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 871 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 929
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 930 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 985
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 986 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1044
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1045 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1096
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1097 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1147
Query: 2074 CTD 2076
C++
Sbjct: 1148 CSE 1150
Score = 49.2 bits (112), Expect = 3e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 181 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 234
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 235 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 287
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 288 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCV 344
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 345 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 403
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 404 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 458
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 459 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 509
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 510 QLCEVETNECASAP---CLNHADCHDLL 534
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 21 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 76
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 77 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCH 136
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 137 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 193
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 194 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 239
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 240 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 294
Query: 2076 DAL 2078
D L
Sbjct: 295 DGL 297
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/378 (24%), Positives = 128/378 (33%), Gaps = 62/378 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 105 CTC-LPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 160
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 161 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 219
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 220 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 268
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY 630
F G C + +P +C+S C G+ D C C + G C E
Sbjct: 269 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCS---EDVD 318
Query: 631 NYPACEECNCDPRGVTASFAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNP 687
A +C G + AG C V C++ + I C P +
Sbjct: 319 ECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGS 378
Query: 688 FGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 379 FSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLCL 421
Query: 748 CDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 422 CQPGYS-GPTCHQDLDEC 438
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 51 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 110
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 111 FTGERCQAQL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 156
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 157 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 203
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 204 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 251
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 252 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 300
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 301 T--CLCPETWTGWDCSEDV 317
Score = 43.2 bits (97), Expect = 0.018
Identities = 83/346 (23%), Positives = 121/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 651 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 706
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 707 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 762
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 763 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 818
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC G+ G + C C + C+C G
Sbjct: 819 NRATCQDSPQGPRC-LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 877
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 878 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 933
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 934 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 969
Score = 41.9 bits (94), Expect = 0.042
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 51 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 110
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 111 FTG---ERCQAQLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 164
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 165 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 219
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 220 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 270
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 271 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRN 330
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 331 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 359
Score = 40.7 bits (91), Expect = 0.097
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 679 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 736
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 737 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 789
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 790 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGS 842
Query: 1508 CDT 1510
C T
Sbjct: 843 CQT 845
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 918 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 973
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 974 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1030
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1031 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1086
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 445 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 497
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 498 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 553
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 554 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 612
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 613 FFCLCPSGFTGQLCE 627
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 211 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 269
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 270 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECEAQG 324
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 325 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 384
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 385 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 426
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 80.2 bits (189), Expect = 1e-13
Identities = 119/486 (24%), Positives = 172/486 (35%), Gaps = 99/486 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 179 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 232
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P C+ NC +C G+
Sbjct: 233 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQD 292
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ P +C GT C + +G C+C
Sbjct: 293 GLDTYT--CLCPETWTGWDCSE---DVDECEAQGPPHCRNGGT----CQNSAGSFHCVCV 343
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 344 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 402
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 403 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 461
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 462 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 509
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 510 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 569
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGSIDNNCDKTTGQ--CHCHSRVEGRRC 776
G C +CL GF R QT +V C C +G S C G C C S G+ C
Sbjct: 570 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS----CLDLPGAFFCLCPSGFTGQLC 623
Query: 777 DQPIRA 782
+ P+ A
Sbjct: 624 EVPLCA 629
Score = 74.1 bits (174), Expect = 9e-12
Identities = 170/649 (26%), Positives = 226/649 (34%), Gaps = 154/649 (23%)
Query: 228 GGRCMCNGHADTCEPADPAGN-LNILV---CRC----QHNTCGPQCNKCCSGFEQKKWRI 279
G RC + + +P P L++L C C + C + N+C S
Sbjct: 468 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 527
Query: 280 SQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNK 339
+ F C C T C D IDE R S NG CQ +C K
Sbjct: 528 HDLLNGFQCI-CLPGFSGTRCEED--IDECRSSPCANGG--------QCQDQPGAFHC-K 575
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR--CECRPEFQPPDCSS--CAY 395
C P + P + E+D C DP +C + G C C F C CA
Sbjct: 576 CLPGFEGP--RCQTEVD---ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 630
Query: 396 GYFDYPN-CKP------CTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPEC 448
CK C C +G+ G C P + C C + + +S +C+ G+ PE
Sbjct: 631 NLCQPKQICKDQKDKANCLCP-DGSPG--CAPPEDNCTCHHGHCQRSSCVCDVGWTGPE- 686
Query: 449 KNCECNTVGSVSYVC-------DKLTG-DCTCKSKYSGRTCNQ----CQAG-YYNYPTCK 495
CE G +S C + +G +CTC + Y+G TC++ C +G N +C
Sbjct: 687 --CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 744
Query: 496 P------CNCDTSGTEP-----------------SICDDVSG--QCICKAGFGGPRCDQC 530
P C C S T P C + G C+C GF GPRC+
Sbjct: 745 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 804
Query: 531 LSGYYMQVLGRER-------QCVPCNCDPTGSTSTSCS------ADGKC----NCLTNFG 573
L R R Q C C PTG T SC A C +CL
Sbjct: 805 LRPSCADSPCRNRATCQDSPQGPRCLC-PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 863
Query: 574 GAQCDQCSPGY------YKYPDC----LSCNCDVSGSI--GSTCDDNG---LCHCKSNFD 618
C C G+ C LS DVS G C D+G CHC F
Sbjct: 864 SFHC-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 922
Query: 619 GAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
G+ C Q + P CE C G T C + P+G LCQC G+ C+
Sbjct: 923 GSLC-----QDHVNP-CESRPCQ-NGAT-----CMAQPSGYLCQCAPGYDGQNCS----- 965
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQ-HVG---ERQCDQCLD-- 730
+E + C+ C+ GT C K G C C VG E D+CLD
Sbjct: 966 ----KELD--ACQSQPCHNHGT------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1013
Query: 731 --GFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
+ + C C + G C+ CH G C+
Sbjct: 1014 CHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPCHSQPCFHGGTCE 1061
Score = 69.3 bits (162), Expect = 2e-10
Identities = 112/445 (25%), Positives = 142/445 (31%), Gaps = 84/445 (18%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLN--------CQHNTEGINC----N 338
C C + T ++DE ++ E GG CLN C G C N
Sbjct: 417 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 476
Query: 339 KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF 398
+C P G +L C C P CE E+ C P DC G+
Sbjct: 477 ECLSQPCHP-GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF- 534
Query: 399 DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE--------ICEDGYYSPECKN 450
C C L G G C C G C+ C G+ P C+
Sbjct: 535 ------QCIC-LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 587
Query: 451 --CEC-NTVGSVSYVCDKLTGD--CTCKSKYSGRTC-------NQCQAGYYNYPTCKPCN 498
EC + V C L G C C S ++G+ C N CQ N
Sbjct: 588 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKAN 647
Query: 499 C----DTSGTEP--SICDDVSG-----QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVP 547
C + G P C G C+C G+ GP C+ L G C P
Sbjct: 648 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 707
Query: 548 ------CNCDPTGSTSTSCSAD-GKCNCLTNFGGAQCDQCSPGYY-------KYPDC-LS 592
C C PTG T +CS + C+ G C+ GYY P C S
Sbjct: 708 QPSGYNCTC-PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS 766
Query: 593 CNCDVSGSI--GSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+ VS G TC + C C F G +C+ P+C + C R
Sbjct: 767 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNR---- 817
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C P G C C G C
Sbjct: 818 --ATCQDSPQGPRCLCPTGYTGGSC 840
Score = 68.9 bits (161), Expect = 3e-10
Identities = 88/329 (26%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESG--RCECRPEF 385
C G C +C P Y + ELD CQ C H G C + G C C P F
Sbjct: 944 CMAQPSGYLC-QCAPGYDGQNCSK--ELDACQSQPCHNH---GTCTPKPGGFHCACPPGF 997
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C D C C+ GT H C C + G+ CE+ D +S
Sbjct: 998 VGLRCEG------DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1051
Query: 446 PECKN---CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTS 502
C + CE + ++C C + G TC+ + P+C +C
Sbjct: 1052 QPCFHGGTCEATAGSPLGFICH-------CPKGFEGPTCS------HRAPSCGFHHCHHG 1098
Query: 503 GT-EPSICDDVSGQCICKAGFGGPRC------------DQCL-SGYYMQVLGRERQCVPC 548
G PS +C C +G+GGP C CL +G + G C
Sbjct: 1099 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1158
Query: 549 NCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ-CS--PGYYKYPDC-LSCNCDVSGSIG-S 603
+C P S C G C G CD CS G + DC L G S
Sbjct: 1159 SC-PHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1217
Query: 604 TC---DDNGLCH--CKSN---FDGAKCDT 624
C +G CH C S FDG C+T
Sbjct: 1218 RCWLLFRDGQCHPQCDSEECLFDGYDCET 1246
Score = 67.7 bits (158), Expect = 7e-10
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 299 CLCPETWTGWDCSEDVD-----------ECEAQG-PPHCR-NGGTCQNSAGSF---HC-V 341
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 342 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 401
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 402 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 456
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 457 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 516
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 517 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 567
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 568 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 603
Score = 67.7 bits (158), Expect = 7e-10
Identities = 98/387 (25%), Positives = 130/387 (33%), Gaps = 65/387 (16%)
Query: 323 GKCLN---CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGR- 378
G CLN C + G C C P++ P + + V PC F+ G C G
Sbjct: 735 GPCLNGGSCNPSPGGYYCT-CPPSHTGPQCQTSTDYCVSAPC-----FNGGTCVNRPGTF 788
Query: 379 -CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
C C FQ P C P+C C T + +P C C Y G SC+
Sbjct: 789 SCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGSCQ 841
Query: 438 ICEDGYYSPEC-KNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCN----QCQAGY---- 488
D C +N C G + C C ++G CN CQ
Sbjct: 842 TLMDLCAQKPCPRNSHCLQTGPSFH--------CLCLQGWTGPLCNLPLSSCQKAALSQG 893
Query: 489 -------YNYPTCKP------CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYY 535
+N C C+C G + S+C D C + G C SGY
Sbjct: 894 IDVSSLCHNGGLCVDSGPSYFCHCPP-GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 952
Query: 536 MQVL-GRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCN 594
Q G + Q C+ + S C G C GG C C PG+ L C
Sbjct: 953 CQCAPGYDGQ--NCSKELDACQSQPCHNHGTCT--PKPGGFHC-ACPPGFVG----LRCE 1003
Query: 595 CDVSGSIGSTCDDNGL--CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTASFA 650
DV + C G CH +N +C + + C+ P G T A
Sbjct: 1004 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE-A 1062
Query: 651 GCGSVPAGELCQCKDRVQGRICNDCKP 677
GS P G +C C +G C+ P
Sbjct: 1063 TAGS-PLGFICHCPKGFEGPTCSHRAP 1088
Score = 58.0 bits (134), Expect = 6e-07
Identities = 92/377 (24%), Positives = 129/377 (34%), Gaps = 58/377 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P ++ CE + C +P C D C C G EG+ C
Sbjct: 460 CLCPPGYTGSRCEADHNECLSQPCHPGSTC-------LDLLATFHCLCP-PGLEGQLCEV 511
Query: 421 TDGLC---PCKYNYA-------GKSCEICEDGYYSPECKN--CECNTVGSVS-YVCDKLT 467
C PC N+A G C IC G+ C+ EC + + C
Sbjct: 512 ETNECASAPC-LNHADCHDLLNGFQC-ICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 569
Query: 468 G--DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
G C C + G C Q + + PC S C D+ G C+C +GF
Sbjct: 570 GAFHCKCLPGFEGPRC-QTEV---DECLSDPCPVGAS------CLDLPGAFFCLCPSGFT 619
Query: 524 GPRCDQCLSGYYM----QVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQ 579
G C+ L + Q+ ++ C C P GS + D NC + G Q
Sbjct: 620 GQLCEVPLCAPNLCQPKQICKDQKDKANCLC-PDGSPGCAPPED---NCTCHHGHCQRSS 675
Query: 580 CSPGY-YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EE 637
C + P+ C ++ G I + C G C+ + + G C TC Y P C EE
Sbjct: 676 CVCDVGWTGPE---CEAELGGCISAPCAHGGTCYPQPS--GYNC-TC-PTGYTGPTCSEE 728
Query: 638 CNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNL 697
G + C P G C C G C + +N C N
Sbjct: 729 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC----VNR 784
Query: 698 AGTLNSLGACNTKSGQC 714
GT + L A + +C
Sbjct: 785 PGTFSCLCAMGFQGPRC 801
Score = 57.6 bits (133), Expect = 8e-07
Identities = 86/351 (24%), Positives = 121/351 (34%), Gaps = 53/351 (15%)
Query: 1736 CQCPRAYRGLSC-EQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTG-ICLNCADNTIGDHC 1793
C CP Y G +C E+ H SG C+ NG S C+ + G C + G C
Sbjct: 714 CTCPTGYTGPTCSEEMTACH----SGPCL----NGGS--CNPSPGGYYCTCPPSHTGPQC 763
Query: 1794 E----FCMSG--YHGDATVGTPRDCLICACPMPY--PSNNFALSCDLSENGSLISCNCQP 1845
+ +C+S ++G V P C C M + P L +++ CQ
Sbjct: 764 QTSTDYCVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 822
Query: 1846 GYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNT 1905
G RC C GY G T + D C C N + G + CL C+
Sbjct: 823 SPQGPRC-LCPTGYTGGSCQTLM---DLCAQKPCPRNSHCLQTGP----SFHCL-CLQGW 873
Query: 1906 AGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKC-DRCAP- 1963
G CNL A+ + +C G+ + C C PG G C D P
Sbjct: 874 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 933
Query: 1964 DHWGLNTGLGCTP------CNCGIASESTQCDDDNGQCR---------CAKGVTGKQCDQ 2008
+ G C C C + C + C+ C G C
Sbjct: 934 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-A 992
Query: 2009 CAAGFWNYTKDG-CDHCNCNTGYSVGFM-CNATGQ---CECLPGVIGEKCD 2054
C GF +G D C + G C++ C+CLPG G+ C+
Sbjct: 993 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE 1043
Score = 56.0 bits (129), Expect = 2e-06
Identities = 88/332 (26%), Positives = 121/332 (36%), Gaps = 49/332 (14%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 51 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 109
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 110 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 162
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 163 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKC----DRCAP 1963
G G + + C C G M + DST C+C PG IG C D C
Sbjct: 222 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVS 281
Query: 1964 ---DHWG-LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKD 2019
+ G GL C C C +D +C A+G C G
Sbjct: 282 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE-AQGP-----PHCRNGGTCQNSA 335
Query: 2020 GCDHCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
G HC C +G+ G C C C PG
Sbjct: 336 GSFHCVCVSGWG-GTSCEENLDDCIAATCAPG 366
Score = 54.0 bits (124), Expect = 1e-05
Identities = 95/380 (25%), Positives = 127/380 (33%), Gaps = 67/380 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G +C Q + G P C H C +NT NC
Sbjct: 417 CLCQPGYSGPTCHQDLDECLMAQQG---PSPCE-HGGSC-LNTPGSFNC----------L 461
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C GY G +CL C +P + DL + C C PG G CE
Sbjct: 462 CPPGYTGSRCEADHNECLSQPC---HPGST---CLDLL---ATFHCLCPPGLEGQLCEVE 512
Query: 1855 ---CA-AGYYGIPEDTDLHTGDYCKPC-NCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
CA A + DL G C SG +D C S NG +C +
Sbjct: 513 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGG--QCQDQPG 570
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGM-ADCDSTTGT--CVCRPGVIGEKCD--RC 1961
C C PGF G ++ C+ D + A C G C+C G G+ C+ C
Sbjct: 571 AFHCK-CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 628
Query: 1962 APD---------HWGLNTGLGCTPCNCGIASESTQCDDDNGQCR-----CAKGVTGKQCD 2007
AP+ C + G A C +G C+ C G TG +C+
Sbjct: 629 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 688
Query: 2008 Q---------CAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
CA G Y + +C C TGY+ C P + G C+ P
Sbjct: 689 AELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 748
Query: 2059 RWVLI--PQEGCLECDSCTD 2076
+ P +C + TD
Sbjct: 749 GYYCTCPPSHTGPQCQTSTD 768
Score = 52.8 bits (121), Expect = 2e-05
Identities = 91/363 (25%), Positives = 118/363 (32%), Gaps = 66/363 (18%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCV--PCQCNGHSDQCDVNTGICLNCADNTIGDHC 1793
C CP Y G SC+ + C PC N H CL + HC
Sbjct: 829 CLCPTGYTGGSCQTLMD--------LCAQKPCPRNSH----------CLQTGPSF---HC 867
Query: 1794 EFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLS-ENGSLISCNCQPGYGGARC 1852
C+ G+ G C A ++ + L ++G C+C PG+ G+ C
Sbjct: 868 -LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 926
Query: 1853 EYCAAGYYGIPEDTDLHTGDYC--KP----CNCSGNINPQDPGS-CDSINGD-CLK---C 1901
+ + E G C +P C C+ + Q+ D+ C C
Sbjct: 927 Q----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 982
Query: 1902 VNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDSTTGT--CVCRPGVIGEK 1957
G C C PGF G C C G A C S C C PG G+
Sbjct: 983 TPKPGGFHC-ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQW 1041
Query: 1958 CD-RCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA--AGFW 2014
C+ P H PC G E+T C C KG G C A GF
Sbjct: 1042 CEVEIDPCH--------SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH 1093
Query: 2015 NYTKDGCDHCN-CNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLECDS 2073
+ C H C GF +C CL G G C P P CL S
Sbjct: 1094 H-----CHHGGLCLPSPKPGF----PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1144
Query: 2074 CTD 2076
C++
Sbjct: 1145 CSE 1147
Score = 49.2 bits (112), Expect = 3e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 178 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 231
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 232 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPGCEVNPD-NCVSHQC 284
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 285 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCV 341
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 342 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 400
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 401 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 455
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 456 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 506
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 507 QLCEVETNECASAP---CLNHADCHDLL 531
Score = 48.0 bits (109), Expect = 6e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 18 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 73
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 74 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 133
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 134 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 190
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 191 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 236
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 237 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCV---SHQCQNGGTCQ 291
Query: 2076 DAL 2078
D L
Sbjct: 292 DGL 294
Score = 47.6 bits (108), Expect = 8e-04
Identities = 91/378 (24%), Positives = 128/378 (33%), Gaps = 62/378 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 102 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 157
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 158 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 216
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 217 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 265
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY 630
F G C + +P +C+S C G+ D C C + G C E
Sbjct: 266 GFIGPGC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCS---EDVD 315
Query: 631 NYPACEECNCDPRGVTASFAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNP 687
A +C G + AG C V C++ + I C P +
Sbjct: 316 ECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGS 375
Query: 688 FGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECD 747
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 FSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLCL 418
Query: 748 CDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 CQPGYS-GPTCHQDLDEC 435
Score = 46.4 bits (105), Expect = 0.002
Identities = 43/162 (26%), Positives = 56/162 (34%), Gaps = 24/162 (14%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 48 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 107
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 108 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 153
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD 623
+ D S N V+G + CHC F+G C+
Sbjct: 154 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE 191
Score = 44.8 bits (101), Expect = 0.006
Identities = 75/329 (22%), Positives = 113/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 48 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 107
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 108 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 161
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 162 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 216
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 217 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 267
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G G + C G C D Y L + + + C ++C +
Sbjct: 268 IGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRN 327
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 328 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 356
Score = 43.2 bits (97), Expect = 0.018
Identities = 83/346 (23%), Positives = 121/346 (34%), Gaps = 53/346 (15%)
Query: 1736 CQCPRAYRGLSCEQ----CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGD 1791
C CP G + + C GH + S CV C +C+ G C++ A G
Sbjct: 648 CLCPDGSPGCAPPEDNCTCHHGHCQRSS--CV-CDVGWTGPECEAELGGCIS-APCAHGG 703
Query: 1792 HCEFCMSGYHGDATVG-TPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
C SGY+ G T C + AC P N SC+ S G C C P +
Sbjct: 704 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-PCLNGG-SCNPSPGGYY--CTCPPSHT 759
Query: 1849 GARCE----YCAAGYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSC-DSING 1896
G +C+ YC + G + C C G + P SC DS
Sbjct: 760 GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----SCADSPCR 815
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAI--FSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
+ C ++ G C LC G+ G + C C + C+C G
Sbjct: 816 NRATCQDSPQGPRC-LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT 874
Query: 1955 GEKCDR--CAPDHWGLNTGLGCTP-C-NCGIASESTQCDDDNGQCRCAKGVTGKQCDQCA 2010
G C+ + L+ G+ + C N G+ +S + C C G G C
Sbjct: 875 GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHV 930
Query: 2011 AGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ-CECLPGVIGEKCDR 2055
+ C+ C G + M +G C+C PG G+ C +
Sbjct: 931 --------NPCESRPCQNGATC--MAQPSGYLCQCAPGYDGQNCSK 966
Score = 40.7 bits (91), Expect = 0.097
Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 28/183 (15%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA--------CRTGYYGFPNC----RPCH 1387
C+CD +G T EC G C P G TC C TGY G P C CH
Sbjct: 676 CVCD-VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG-PTCSEEMTACH 733
Query: 1388 CPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
+ C + G C + G C C P Q D C P G
Sbjct: 734 ---SGPCLNGGS--CNPSPGGYYC-TCPPSHTGPQCQTSTDYCVSAPC-FNGGTCVNRPG 786
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQA 1507
+ C C +G C+ + P C C T D +C C T G +
Sbjct: 787 TFSCLCAMGFQGPRCEGKLR-----PSCADSPCRNRATCQD--SPQGPRCLCPTGYTGGS 839
Query: 1508 CDT 1510
C T
Sbjct: 840 CQT 842
Score = 38.7 bits (86), Expect = 0.39
Identities = 44/177 (24%), Positives = 59/177 (33%), Gaps = 35/177 (19%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG-MCICPKNVEGENC----DR 1413
C C P G C + RPC +T + +G +C C +G+NC D
Sbjct: 915 CHCPPGFQGSLCQ----DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 970
Query: 1414 CKPYTFN----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKC-----------ACRENVR 1458
C+ + + G C C P G VG L+CE D +C AC
Sbjct: 971 CQSQPCHNHGTCTPKPGGFHCACPP-GFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1027
Query: 1459 GRVCDHCVPGH------YAFPDCYQCTCNRHGTTYDVCDQNTA-QCYCKTNVRGQAC 1508
C C+PGH C+ C GT C+C G C
Sbjct: 1028 AFYC-QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1083
Score = 36.3 bits (80), Expect = 2.1
Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 36/195 (18%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 442 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 494
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 495 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 550
Query: 1448 SGKCACRENVRGRVCD--------HCVPGHYAFPDCY----QCTCNRHGTTYDVCDQNTA 1495
+C G C C+PG + P C +C + D A
Sbjct: 551 IDECRSSPCANGGQCQDQPGAFHCKCLPG-FEGPRCQTEVDECLSDPCPVGASCLDLPGA 609
Query: 1496 -QCYCKTNVRGQACD 1509
C C + GQ C+
Sbjct: 610 FFCLCPSGFTGQLCE 624
Score = 34.3 bits (75), Expect = 8.4
Identities = 47/164 (28%), Positives = 54/164 (32%), Gaps = 32/164 (19%)
Query: 1358 QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD---NGMCICPKNVEGENCD-R 1413
QC C P G C R F + PC P C + + C+CP EG C+ R
Sbjct: 178 QCHCPPGFEGHACE--RDVNECFQDPGPC--PKGTSCHNTLGSFQCLCPVGQEGPRCELR 233
Query: 1414 CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADS--GKCACRENVRGRVCDHCVPGHYA 1471
P C C+ G QL E DS C C G PG
Sbjct: 234 AGP----------CPPRGCSNGGTC--QLMPEKDSTFHLCLCPPGFIG-------PGCEV 274
Query: 1472 FPD-CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
PD C C GT D D T C C G C +E
Sbjct: 275 NPDNCVSHQCQNGGTCQDGLD--TYTCLCPETWTGWDCSEDVDE 316
>AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens
cDNA FLJ14712 fis, clone NT2RP3000825, weakly similar to
NEUROGENIC LOCUS NOTCH 3 PROTEIN. ).
Length = 849
Score = 79.4 bits (187), Expect = 2e-13
Identities = 85/321 (26%), Positives = 124/321 (38%), Gaps = 59/321 (18%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGT--EGEHC 418
C+C P + NC+ + C+ PDC + +G PN C G + EHC
Sbjct: 573 CKCKPGYIGSNCQ--TALCD-------PDCKN--HGKCIKPNICQCLPGHGGATCDEEHC 621
Query: 419 TPTDGLCPCKYN---YAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD-CTCKS 474
P PC++ AG C C G+ P C+ CN C LT D C CK
Sbjct: 622 NP-----PCQHGGICLAGNLCT-CPYGFVGPRCETMVCNRHCENGGQC--LTPDICQCKP 673
Query: 475 KYSGRTCNQ--CQAGYYNYPTC-KPCNC-DTSGTEPSICDDVSGQCICKAGFGGPRCDQC 530
+ G TC+ C N +C KP C +G C + CK G R + C
Sbjct: 674 GWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVC 733
Query: 531 L--SGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP 588
+ GY R+C CDPT C C+C + + G +C+ P
Sbjct: 734 VCREGY------TGRRCQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNT--------P 779
Query: 589 DCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE-ECNCDPRGVTA 647
CL C G C +CHC S+++G +C P C +C R +
Sbjct: 780 ICLQ-KC----KNGGECIAPSICHCPSSWEGVRC--------QIPICNPKCLYGGRCIFP 826
Query: 648 SFAGCGSVPAGELCQCKDRVQ 668
+ C + +G C+ K +++
Sbjct: 827 NVCSCRTEYSGVKCEKKIQIR 847
Score = 61.7 bits (143), Expect = 5e-08
Identities = 110/411 (26%), Positives = 146/411 (35%), Gaps = 70/411 (17%)
Query: 404 KPCTCNLNG---TEGEHCTPTDG--LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGS 458
K C C LNG + +P G LC C + G CE+ G S C G
Sbjct: 438 KSCDC-LNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGF 495
Query: 459 VSYVCD---KLTGDCTCKSKYSGRTCNQCQAGYY--------NYPTCKPCNCDTSGTEPS 507
SY CD +L + +K++ +T ++ N K TSG +
Sbjct: 496 HSYSCDCPPELKVETQFVNKFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFT 555
Query: 508 ICDDVSGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKC 566
IC G+ C A P +C GY +G C CDP C C
Sbjct: 556 ICKYPCGKSRECVA----PNICKCKPGY----IGSN--CQTALCDPDCKNHGKCIKPNIC 605
Query: 567 NCLTNFGGAQCDQ--CSPGYYKYPDCLS---CNCDVSGSIGSTCDDNGLC--HCKSNFDG 619
CL GGA CD+ C+P CL+ C C G +G C+ +C HC++ G
Sbjct: 606 QCLPGHGGATCDEEHCNPPCQHGGICLAGNLCTCPY-GFVGPRCETM-VCNRHCEN---G 660
Query: 620 AKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICND 674
+C T C+ +Y P C CDP + GS C C + G C +
Sbjct: 661 GQCLTPDICQCKPGWYG-PTCSTALCDPVCLNG-----GSCNKPNTCLCPNGFFGEHCQN 714
Query: 675 --CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNT---KSGQCVCKQHVGERQCDQCL 729
C P N C G C+ G+CV G C C
Sbjct: 715 AFCHPPCKNGGHCMRNNVCVCREGYTGRRCQKSICDPTCMNGGKCV-----GPSTCS-CP 768
Query: 730 DGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
G+ + N C + C GG C + CHC S EG RC PI
Sbjct: 769 SGWSGKRCNTPI-CLQ-KCKNGGE----CIAPS-ICHCPSSWEGVRCQIPI 812
Score = 57.6 bits (133), Expect = 8e-07
Identities = 81/280 (28%), Positives = 110/280 (39%), Gaps = 64/280 (22%)
Query: 1807 GTPRDCL---ICACPMPYPSNNFALS-CD--LSENGSLIS---CNCQPGYGGARC--EYC 1855
G R+C+ IC C Y +N + CD +G I C C PG+GGA C E+C
Sbjct: 562 GKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHC 621
Query: 1856 --AAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI--NGDCLKCVNNTAGAACN 1911
+ GI +L T Y G + P+ C+++ N C C
Sbjct: 622 NPPCQHGGICLAGNLCTCPY-------GFVGPR----CETMVCNRHCENGGQCLTPDICQ 670
Query: 1912 LCAPGFYGDAIFSKNCTACICDEFGM--ADCDSTTGTCVCRPGVIGEKCDR--CAPDHWG 1967
C PG+YG C+ +CD + C+ TC+C G GE C C P
Sbjct: 671 -CKPGWYG-----PTCSTALCDPVCLNGGSCNK-PNTCLCPNGFFGEHCQNAFCHP---- 719
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQ--CAAGFWNYTK-DGCDHC 2024
PC G C +N C C +G TG++C + C N K G C
Sbjct: 720 --------PCKNG-----GHCMRNN-VCVCREGYTGRRCQKSICDPTCMNGGKCVGPSTC 765
Query: 2025 NCNTGYSVGFMCNATGQC--ECLPG--VIGEKCDRCPERW 2060
+C +G+S G CN T C +C G I CP W
Sbjct: 766 SCPSGWS-GKRCN-TPICLQKCKNGGECIAPSICHCPSSW 803
Score = 43.2 bits (97), Expect = 0.018
Identities = 47/178 (26%), Positives = 65/178 (36%), Gaps = 19/178 (10%)
Query: 1335 SGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAIC 1394
SG +C + EC C CKP IG S C+T C P C + C
Sbjct: 550 SGNAFTICKYPCGKSREC-VAPNICKCKPGYIG---SNCQTAL-----CDP-DCKNHGKC 599
Query: 1395 DDNGMCICPKNVEGENCD--RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
+C C G CD C P + + + C C P G VG + + + C
Sbjct: 600 IKPNICQCLPGHGGATCDEEHCNPPCQHGGICLAGNLCTC-PYGFVGPRCETMVCNRHCE 658
Query: 1453 -CRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQ-NTAQCYCKTNVRGQAC 1508
+ + +C C PG Y P C C+ C++ NT C C G+ C
Sbjct: 659 NGGQCLTPDIC-QCKPGWYG-PTCSTALCDPVCLNGGSCNKPNT--CLCPNGFFGEHC 712
Score = 37.9 bits (84), Expect = 0.68
Identities = 39/159 (24%), Positives = 56/159 (35%), Gaps = 16/159 (10%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI----CDDNGMCICPKNVEGENC 1411
GGQC P++ C C+ G+YG P C C + C+ C+CP GE+C
Sbjct: 660 GGQC-LTPDI----CQ-CKPGWYG-PTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHC 712
Query: 1412 DR--CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGH 1469
C P N + C C G G + Q C G C P
Sbjct: 713 QNAFCHPPCKNGGHCMRNNVCVCRE-GYTGRRCQKSICDPTCMNGGKCVGPSTCSC-PSG 770
Query: 1470 YAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
++ C C + C + C+C ++ G C
Sbjct: 771 WSGKRCNTPICLQKCKNGGECIAPSI-CHCPSSWEGVRC 808
Score = 34.7 bits (76), Expect = 6.4
Identities = 36/153 (23%), Positives = 47/153 (30%), Gaps = 16/153 (10%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCDR--CKP 1416
C C P G TC +C P C IC +C CP G C+ C
Sbjct: 605 CQCLPGHGGATCDE--------EHCNP-PCQHGGICLAGNLCTCPYGFVGPRCETMVCNR 655
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCV-PGHYAFPDC 1475
+ N D C C P G G C C + C+ P + C
Sbjct: 656 HCENGGQCLTPDICQCKP-GWYGP--TCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHC 712
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C+ C +N C C+ G+ C
Sbjct: 713 QNAFCHPPCKNGGHCMRNNV-CVCREGYTGRRC 744
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 79.0 bits (186), Expect = 3e-13
Identities = 92/356 (25%), Positives = 134/356 (37%), Gaps = 69/356 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C DG+ ECK C ++ + + G+C C + GR C++C YP C +
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDEC----VPYPGCVHGS 286
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C EP QC C+ +GG CD+ L+ G C G T
Sbjct: 287 C----VEP-------WQCNCETNWGGLLCDKDLN-----YCGSHHPCT------NGGTCI 324
Query: 559 SCSADG-KCNCLTNFGGAQCDQ---------CSPG--YYKYPDCLSCNCDVSGSIGSTCD 606
+ D +C C + G C++ C+ G ++ P C+C SG G TC
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP-SGWSGPTCA 383
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA----GCGSVPAGELCQ 662
+ + C SN A TC +Q + EC C + V A+ C P
Sbjct: 384 LD-IDECASN-PCAAGGTCVDQVDGF----ECICPEQWVGATCQLDANECEGKPCLNAFS 437
Query: 663 CKDRVQGRICNDCKPLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVG 721
CK+ + G C DC P + + N C + C GT L QCVC + G
Sbjct: 438 CKNLIGGYYC-DCIPGWKGINCHINVNDC-RGQCQHGGTCKDL----VNGYQCVCPRGFG 491
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R C+ L+ ++ C C GG ++ D CHC G C+
Sbjct: 492 GRHCE--------LERDE---CASSPCHSGGLCEDLADGF--HCHCPQGFSGPLCE 534
Score = 74.1 bits (174), Expect = 9e-12
Identities = 138/550 (25%), Positives = 192/550 (34%), Gaps = 101/550 (18%)
Query: 255 RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLD 314
RC N CNK C + + D++ + C EC + ++ +L
Sbjct: 197 RCDENYYSATCNKFCR--PRNDFFGHYTCDQYGNKACMDGWMGKEC--KEAVCKQGCNL- 251
Query: 315 INGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEE 374
++G G+C C + +G C++C P +G +P QC NCE
Sbjct: 252 LHGGCTVPGEC-RCSYGWQGRFCDECVPYPGCVHG------SCVEPWQC-------NCET 297
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGK 434
G C D + C + PCT NG + P C C Y+G+
Sbjct: 298 NWGGLLC-----DKDLNYCGSHH-------PCT---NGGTCINAEPDQYRCTCPDGYSGR 342
Query: 435 SCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT 493
+CE E S C N C+ V S +C C S +SG TC +
Sbjct: 343 NCEKAEHACTSNPCANGGSCHEVPS--------GFECHCPSGWSGPTC------ALDIDE 388
Query: 494 CKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCD---------QCLSGYYMQVL--GR 541
C C GT D V G +CIC + G C CL+ + + L G
Sbjct: 389 CASNPCAAGGT---CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGY 445
Query: 542 ERQCVP----CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY------YKYPDC 590
C+P NC C G C L N G QC C G+ + +C
Sbjct: 446 YCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVN--GYQC-VCPRGFGGRHCELERDEC 502
Query: 591 LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA 650
S C SG + D CHC F G C+ + CE C + A
Sbjct: 503 ASSPCH-SGGLCEDLADGFHCHCPQGFSGPLCEV------DVDLCEPSPC------RNGA 549
Query: 651 GCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGC-EQCNCNLAGTLNSLGACN 708
C ++ C C D G+ C+ +P GC + GT S G C
Sbjct: 550 RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVID-GCGSDAGPGMPGTAAS-GVCG 607
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G+CV Q G C C GF ++ + C C GG+ + D +C C
Sbjct: 608 -PHGRCV-SQPGGNFSC-ICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD--AFRCFC 662
Query: 768 HSRVEGRRCD 777
S EG CD
Sbjct: 663 PSGWEGELCD 672
Score = 67.7 bits (158), Expect = 7e-10
Identities = 137/576 (23%), Positives = 189/576 (32%), Gaps = 110/576 (19%)
Query: 228 GGRCMCNGHADTCEPADPAGNLNILV----CRCQHNTCGPQC----NKCCSGFEQKKWRI 279
G C HA T P G+ + + C C GP C ++C S
Sbjct: 341 GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400
Query: 280 SQNWDRFSC------EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEG---GGKCLNCQH 330
D F C C EC P ++ I G Y G K +NC
Sbjct: 401 VDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460
Query: 331 NTE--------GINCNKCRPTYY----RPYGKRWDELDVCQPCQCDPHFSTGNCEE--ES 376
N G C Y R +G R EL+ + C P S G CE+ +
Sbjct: 461 NVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDE-CASSPCHSGGLCEDLADG 519
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDG--LCPCKYNYAGK 434
C C F P C D C+P C G C +G C C ++ GK
Sbjct: 520 FHCHCPQGFSGPLCE------VDVDLCEPSPCR----NGARCYNLEGDYYCACPDDFGGK 569
Query: 435 SCEICEDGYYSPECKNCE-CNTVGSVSYVCDKLTGDC----TCKSKYSGRTCNQCQAGYY 489
+C + + C+ + C + +G C C S+ G C +G+
Sbjct: 570 NCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT 629
Query: 490 ------NYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGRE 542
N C C GT D+V +C C +G+ G CD
Sbjct: 630 GTYCHENIDDCLGQPCRNGGT---CIDEVDAFRCFCPSGWEGELCDT-----------NP 675
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIG 602
C+P DP C + G+C L N CD G + C+ + S G
Sbjct: 676 NDCLP---DP-------CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA-YTCSNG 724
Query: 603 STCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
TC D+G C C + G+ C + +C C G C A
Sbjct: 725 GTCYDSGDTFRCACPPGWKGSTCAVAKNS-----SCLPNPCVNGGT------CVGSGASF 773
Query: 660 LCQCKDRVQGRIC----NDCKPL-YWN----LQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
C C+D +GR C NDC PL +N + N F CE C AG + +
Sbjct: 774 SCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQ 832
Query: 711 SGQC----VCKQHVGERQCDQCLDGFYRLQTNDVFG 742
S C C + +C C G + +V G
Sbjct: 833 SSPCAYGATCVDEINGYRC-SCPPGRAGPRCQEVIG 867
Score = 64.9 bits (151), Expect = 5e-09
Identities = 91/336 (27%), Positives = 124/336 (36%), Gaps = 62/336 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCV-PCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
EC+C ++G C++C + G CV P QCN C+ N G L D N G H
Sbjct: 261 ECRCSYGWQGRFCDECVP-YPGCVHGSCVEPWQCN-----CETNWGGLLCDKDLNYCGSH 314
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C +G + D C CP Y N C+ +E+ +C P G C
Sbjct: 315 -HPCT---NGGTCINAEPDQYRCTCPDGYSGRN----CEKAEH----ACTSNPCANGGSC 362
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ +P + H C P SG D C S C AG C
Sbjct: 363 -------HEVPSGFECH----C-PSGWSGPTCALDIDECAS--NPC------AAGGTCVD 402
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDS--TTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
GF + I + C + +C+ C+ + G CD C P G+N
Sbjct: 403 QVDGF--ECICPEQWVGATC-QLDANECEGKPCLNAFSCKNLIGGYYCD-CIPGWKGINC 458
Query: 1971 GLGCTPCNCGIASESTQCDD-DNG-QCRCAKGVTGKQC----DQCAA------GFWNYTK 2018
+ C G C D NG QC C +G G+ C D+CA+ G
Sbjct: 459 HINVNDCR-GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLA 517
Query: 2019 DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKC 2053
DG HC+C G+S G +C CE P G +C
Sbjct: 518 DGF-HCHCPQGFS-GPLCEVDVDLCEPSPCRNGARC 551
Score = 61.7 bits (143), Expect = 5e-08
Identities = 100/375 (26%), Positives = 128/375 (34%), Gaps = 67/375 (17%)
Query: 1734 EECQCPRAYRGLSCEQCAEG-HYRLPSGFCVPCQCNGHSDQCDVNTGICLNCAD--NTIG 1790
+EC + G CE A+G H P GF P C D C+ + C N A N G
Sbjct: 500 DECASSPCHSGGLCEDLADGFHCHCPQGFSGPL-CEVDVDLCEPSP--CRNGARCYNLEG 556
Query: 1791 DHCEFCMSGYHGDATVGTPRD-CLICACPM----------PYPSNNFALSCD-----LSE 1834
D+ C + G PR+ C AC + P + C +S+
Sbjct: 557 DYYCACPDDF-GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGD----YCKPCNCSGNI---N 1884
G SC C G+ G C G P T + D +C P G + N
Sbjct: 616 PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTN 674
Query: 1885 PQD--PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADC 1940
P D P C S G C VN+ A C G+ G S+ C A C G
Sbjct: 675 PNDCLPDPCHS-RGRCYDLVNDFYCA----CDDGWKGKTCHSREFQCDAYTCSNGGTCYD 729
Query: 1941 DSTTGTCVCRPGVIGEKC-----DRCAPD---HWGLNTGLGCT-PCNCGIASESTQCDDD 1991
T C C PG G C C P+ + G G G + C C E C +
Sbjct: 730 SGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN 789
Query: 1992 NGQCR---------CAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNA 2038
C C GV +C+ CA GF D C C G + N
Sbjct: 790 TNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEING 848
Query: 2039 TGQCECLPGVIGEKC 2053
+C C PG G +C
Sbjct: 849 Y-RCSCPPGRAGPRC 862
Score = 49.2 bits (112), Expect = 3e-04
Identities = 64/242 (26%), Positives = 88/242 (36%), Gaps = 45/242 (18%)
Query: 1784 CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C D C FC SG+ G+ P DCL P P ++ DL + C C
Sbjct: 651 CIDEVDAFRC-FCPSGWEGELCDTNPNDCL------PDPCHSRGRCYDLVND---FYCAC 700
Query: 1844 QPGYGGARC---EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI--NGDC 1898
G+ G C E+ Y T +GD + C C P GS ++ N C
Sbjct: 701 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR-CACP----PGWKGSTCAVAKNSSC 755
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTC---------V 1948
L N C G G + S +CIC D + C T C +
Sbjct: 756 LP----------NPCVNG--GTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 803
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC-DDDNG-QCRCAKGVTGKQC 2006
C GV +C+ CAP G + + C + C D+ NG +C C G G +C
Sbjct: 804 CVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 862
Query: 2007 DQ 2008
+
Sbjct: 863 QE 864
Score = 43.2 bits (97), Expect = 0.018
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 34/193 (17%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC--SACRTGYYG 1379
C E +S T N RP DF G C+ +G + C +G+ C + C+ G
Sbjct: 198 CDENYYSATC--NKFCRP-RNDFFG--HYTCDQYGNKA-CMDGWMGKECKEAVCKQG--- 248
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
C H C G C C +G CD C PY GC +C V
Sbjct: 249 ---CNLLH----GGCTVPGECRCSYGWQGRFCDECVPYP-------GCVHGSC----VEP 290
Query: 1440 NQLQCEADSGKCACRENVRGRVCDH-CVPGH---YAFPDCYQCTCNRHGTTYDVCDQNTA 1495
Q CE + G C +++ H C G A PD Y+CTC G + C++
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEH 349
Query: 1496 QCYCKTNVRGQAC 1508
C G +C
Sbjct: 350 ACTSNPCANGGSC 362
Score = 42.7 bits (96), Expect = 0.024
Identities = 43/158 (27%), Positives = 55/158 (34%), Gaps = 28/158 (17%)
Query: 1383 CRPCHCPSTAIC---DDNGMCICPKNVEGENC----DRCKPYTFNFDVQRGCDDCNCNP- 1434
C P C + A C + + C CP + G+NC + C G D P
Sbjct: 540 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPG 599
Query: 1435 ---LGVVGNQLQCEADSG---KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD 1488
GV G +C + G C C G C H DC C GT D
Sbjct: 600 TAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC------HENIDDCLGQPCRNGGTCID 653
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
D +C+C + G+ CDT N D PD C
Sbjct: 654 EVD--AFRCFCPSGWEGELCDT------NPNDCLPDPC 683
Score = 40.3 bits (90), Expect = 0.13
Identities = 85/339 (25%), Positives = 112/339 (33%), Gaps = 57/339 (16%)
Query: 1730 ATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNC--ADN 1787
A ++EC G +C +G + V C +++C+ CLN N
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKN 440
Query: 1788 TIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
IG + C+ G+ G DC C +C NG C C G+
Sbjct: 441 LIGGYYCDCIPGWKGINCHINVNDCR-GQC-------QHGGTCKDLVNG--YQCVCPRGF 490
Query: 1848 GGARCEY----CAAG---YYGIPEDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCL 1899
GG CE CA+ G+ E DL G +C P SG + D C+
Sbjct: 491 GGRHCELERDECASSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEP-----S 543
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTCVCRPGVIGEKC 1958
C N GA C +Y C C D+FG +C C PG
Sbjct: 544 PCRN---GARCYNLEGDYY-----------CACPDDFGGKNCSVPREPC---PGGACRVI 586
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
D C D G + CG N C C G TG C +
Sbjct: 587 DGCGSDAGPGMPGTAASGV-CGPHGRCVSQPGGNFSCICDSGFTGTYCHE--------NI 637
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
D C C G + +A +C C G GE CD P
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAF-RCFCPSGWEGELCDTNP 675
Score = 38.3 bits (85), Expect = 0.52
Identities = 41/150 (27%), Positives = 48/150 (32%), Gaps = 14/150 (9%)
Query: 1920 DAIFSKNCTACICDE---FGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP 1976
D K C +C + C + G C C G G CD C P + G G P
Sbjct: 233 DGWMGKECKEAVCKQGCNLLHGGC-TVPGECRCSYGWQGRFCDECVP-YPGCVHGSCVEP 290
Query: 1977 --CNCGIASESTQCDDDNGQCRCAKGVT-GKQCDQCAAGFWNYT-KDGCDHCNCNTG--Y 2030
CNC CD D C T G C + T DG NC
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Query: 2031 SVGFMCNATGQCECLPGVIGEKCDRCPERW 2060
C G C +P G +C CP W
Sbjct: 351 CTSNPCANGGSCHEVPS--GFEC-HCPSGW 377
Score = 36.7 bits (81), Expect = 1.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 15/61 (24%)
Query: 1449 GKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+C C +GR CD CVP +P C HG+ + QC C+TN G C
Sbjct: 260 GECRCSYGWQGRFCDECVP----YPGCV------HGSCVE-----PWQCNCETNWGGLLC 304
Query: 1509 D 1509
D
Sbjct: 305 D 305
Score = 36.3 bits (80), Expect = 2.1
Identities = 47/190 (24%), Positives = 74/190 (38%), Gaps = 38/190 (20%)
Query: 1340 CLC--DFMGST-ELECNTFGGQCPCK-----PNVIGRTCSACRTGYYGFP---NCRPCH- 1387
C+C ++G+T +L+ N G+ PC N+IG C G+ G N C
Sbjct: 409 CICPEQWVGATCQLDANECEGK-PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG 467
Query: 1388 -CPSTAICDD--NG-MCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ 1443
C C D NG C+CP+ G +C +++R D+C +P G +
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHC----------ELER--DECASSPCH-SGGLCE 514
Query: 1444 CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
AD C C + G +C+ V C C Y++ + C C +
Sbjct: 515 DLADGFHCHCPQGFSGPLCEVDV------DLCEPSPCRNGARCYNL--EGDYYCACPDDF 566
Query: 1504 RGQACDTCKE 1513
G+ C +E
Sbjct: 567 GGKNCSVPRE 576
Score = 35.9 bits (79), Expect = 2.8
Identities = 39/153 (25%), Positives = 46/153 (30%), Gaps = 29/153 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG---MCICPKNVEGENCDRCK 1415
C C G+TC + C C + C D+G C CP +G C K
Sbjct: 698 CACDDGWKGKTCHSREF------QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 1416 PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDC 1475
C NP V G S C CR+ GR C H DC
Sbjct: 752 N-----------SSCLPNPC-VNGGTCVGSGASFSCICRDGWEGRTCTHNT------NDC 793
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C G D N +C C G C
Sbjct: 794 NPLPCYNGGICVD--GVNWFRCECAPGFAGPDC 824
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 78.2 bits (184), Expect = 5e-13
Identities = 111/455 (24%), Positives = 162/455 (35%), Gaps = 93/455 (20%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C C P F CE + C FQ P + C C + G EG C
Sbjct: 180 CHCPPGFEGHACERDVNEC-----FQDPGPCPKGTSCHNTLGSFQCLCPV-GQEGPRCEL 233
Query: 421 TDGLCPCKYNYAGKSCE------------ICEDGYYSPECK----NC---ECNTVGSVSY 461
G CP + G +C+ +C G+ P+C+ NC +C G+
Sbjct: 234 RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 462 VCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSG--QCICK 519
D T C C ++G C++ T P +C GT C + +G C+C
Sbjct: 294 GLDTYT--CLCPETWTGWDCSE---DVDECETQGPPHCRNGGT----CQNSAGSFHCVCV 344
Query: 520 AGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTGSTSTSCSADGKCNCLTNFG 573
+G+GG C++ L C+ C C P G T C + C G
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC-PPGRTGLLCHLEDMCLSQPCHG 403
Query: 574 GAQCDQ----------CSPGY------YKYPDCLSCN-----CDVSGSIGSTCDDNGLCH 612
AQC C PGY +CL C+ GS +T + C
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCL 462
Query: 613 CKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
C + G++C+ + + P C P G T C + A C C ++G++C
Sbjct: 463 CPPGYTGSRCEADHNECLSQP------CHP-GST-----CLDLLATFHCLCPPGLEGQLC 510
Query: 673 ----NDC--KPLYWNLQEYNPFGCEQCNC--NLAGTLNSLGACNTKSGQCV----CKQHV 720
N+C P + ++ QC C +GT +S C C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
Query: 721 GERQCDQCLDGFY--RLQTNDVFGCTECDCDIGGS 753
G C +CL GF R QT +V C C +G S
Sbjct: 571 GAFHC-KCLPGFEGPRCQT-EVDECLSDPCPVGAS 603
Score = 67.3 bits (157), Expect = 1e-09
Identities = 85/338 (25%), Positives = 122/338 (36%), Gaps = 53/338 (15%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP + G C + + C+ G C N G C N A + HC
Sbjct: 300 CLCPETWTGWDCSEDVD-----------ECETQG-PPHCR-NGGTCQNSAGSF---HC-V 342
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPS----NNFALSCDLSENGSLIS----CNCQPGY 1847
C+SG+ G + DC+ C +F+ C G L C QP +
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 402
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAG 1907
G A+C + ++G C + Q P C+ G CL NT G
Sbjct: 403 GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH-GGSCL----NTPG 457
Query: 1908 AACNLCAPGFYGDAIFSKN--CTACICDEFGMADCDSTTGTCVCRPGVIGEKCD----RC 1961
+ LC PG+ G + + C + C T C+C PG+ G+ C+ C
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 1962 AP----DHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYT 2017
A +H + L C C T+C++D +CR + G QC
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--------- 568
Query: 2018 KDGCDHCNCNTGYSVGFMCNATGQCECL--PGVIGEKC 2053
+ G HC C G+ G C T ECL P +G C
Sbjct: 569 QPGAFHCKCLPGFE-GPRCQ-TEVDECLSDPCPVGASC 604
Score = 62.1 bits (144), Expect = 4e-08
Identities = 122/472 (25%), Positives = 164/472 (34%), Gaps = 79/472 (16%)
Query: 258 HNTCGP-QCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK-RLSLDI 315
HNT G QC C G E + + C P C N T C PE D L L
Sbjct: 212 HNTLGSFQC-LCPVGQEGPRCELRAG----PCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 316 NGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE 375
G + G +C+ N + ++C+ G D LD C C ++ +C E+
Sbjct: 266 PG-FIGP----DCEVNPDNCVSHQCQNG-----GTCQDGLDT-YTCLCPETWTGWDCSED 314
Query: 376 SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
CE + PP C + + C C ++G G C C G +
Sbjct: 315 VDECETQG---PPHCRNGGTCQ-NSAGSFHCVC-VSGWGGTSCEENLDDCIAATCAPGST 369
Query: 436 CEICEDGYYSPECKNCECNTVGSVSYVC--DKLTGDCTCKSK-YSGRTCNQCQAGYYNYP 492
C I G +S C + + +C GD C + +G T CQ GY P
Sbjct: 370 C-IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSG-P 427
Query: 493 TCKP----CNCDTSGTEP----SICDDVSGQ--CICKAGFGGPRCD----QCLS------ 532
TC C G P C + G C+C G+ G RC+ +CLS
Sbjct: 428 TCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPG 487
Query: 533 GYYMQVLGRER-QCVP------CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY 585
+ +L C P C + S C C+ L N G QC C PG+
Sbjct: 488 STCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLN--GFQCI-CLPGFS 544
Query: 586 KY---PDCLSCNCDVSGSIGSTCDDNGLCHCKS--NFDGAKCDTCREQFYNYPACEECNC 640
D C + G D G HCK F+G +C T +EC
Sbjct: 545 GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---------EVDECLS 595
Query: 641 DPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ 692
DP V AS C +P C C G K L + + PFG Q
Sbjct: 596 DPCPVGAS---CLDLPGAFFCLCPSGFTGSQGRHWKEL---AEYFIPFGLGQ 641
Score = 58.0 bits (134), Expect = 6e-07
Identities = 97/364 (26%), Positives = 131/364 (35%), Gaps = 77/364 (21%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQC-NGHSDQC----DVNTGICLNCADNTI 1789
+C CP G CE L +G C P C NG + Q D +CL C I
Sbjct: 219 QCLCPVGQEGPRCE--------LRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL-CPPGFI 269
Query: 1790 GDHCEF----CMSGYHGDATVGTPRDCL---ICACPMPYPSNNFALSCDLSENGSLISCN 1842
G CE C+S H GT +D L C CP + + + D E C
Sbjct: 270 GPDCEVNPDNCVS--HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCR 327
Query: 1843 ----CQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDC 1898
CQ G C C +G+ G + +L D C C+ PGS
Sbjct: 328 NGGTCQNSAGSFHC-VCVSGWGGTSCEENL---DDCIAATCA-------PGST------- 369
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGT--CVCRPGVIG 1955
C++ +C LC PG G ++ C + C + TG+ C+C+PG G
Sbjct: 370 --CIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSG 426
Query: 1956 EKC----DRC-------AP-DHWG--LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGV 2001
C D C +P +H G LNT G C C ++C+ D+ +C
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEADHNECLSQPCH 485
Query: 2002 TGKQCDQCAAGFWNYTKDGCDH--CNCNTGYSVGFMC-NATG--------QCECLPGVIG 2050
G C A F G + C T C N QC CLPG G
Sbjct: 486 PGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSG 545
Query: 2051 EKCD 2054
+C+
Sbjct: 546 TRCE 549
Score = 56.0 bits (129), Expect = 2e-06
Identities = 84/329 (25%), Positives = 124/329 (37%), Gaps = 43/329 (13%)
Query: 1749 QCAEGHYRLPSGFCVPCQ----C-NGHSDQCDVNTGICLNCADNTIGDH--CEFCMSGYH 1801
QCA G F PCQ C NG S Q + + L + + + C C+ G+
Sbjct: 52 QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCT-CLPGFT 110
Query: 1802 GDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE---YCAAG 1858
G+ D CP + S C + +G C+C PG+ G +C+ +C+A
Sbjct: 111 GERCQAKLED----PCPPSFCSKRGR--CHIQASGRP-QCSCMPGWTGEQCQLRDFCSAN 163
Query: 1859 YY---GIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK--CVNNTAGAACNLC 1913
G+ T +C P G+ +D C G C K +NT G+ LC
Sbjct: 164 PCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Query: 1914 APGFYGDA--IFSKNCTACICDEFG----MADCDSTTGTCVCRPGVIGEKCDRCAPDHWG 1967
G G + + C C G M + DST C+C PG IG C+ PD+
Sbjct: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE-VNPDNCV 281
Query: 1968 LNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-----QCAAGFWNYTKDGCD 2022
+ C G+ + + C + C++ V +C+ C G G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSF 339
Query: 2023 HCNCNTGYSVGFMCNAT-GQC---ECLPG 2047
HC C +G+ G C C C PG
Sbjct: 340 HCVCVSGWG-GTSCEENLDDCIAATCAPG 367
Score = 48.8 bits (111), Expect = 4e-04
Identities = 96/388 (24%), Positives = 146/388 (37%), Gaps = 78/388 (20%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +CE+ ++ P PC G S + + CL C G CE
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPG----PCP-KGTSCHNTLGSFQCL-CPVGQEGPRCE 232
Query: 1795 F---------CMSGYHGDATVGTPRDCL--ICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C +G G + +D +C CP + C+++ + + +S C
Sbjct: 233 LRAGPCPPRGCSNG--GTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPD-NCVSHQC 285
Query: 1844 QPGYGGARCEYCAAGYYGI-PED-TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD--CL 1899
Q G C+ Y + PE T + C G + ++ G+C + G C+
Sbjct: 286 Q---NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1900 KCVNNTAGAAC--NL-------CAPGFYG-DAIFSKNC------TACICDE--------- 1934
CV+ G +C NL CAPG D + S +C T +C
Sbjct: 343 -CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1935 FGMADCDST--TGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
G A C + TG+ C+C+PG G C + + L G +PC G + +T
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE--CLMAQQGPSPCEHGGSCLNT---P 456
Query: 1991 DNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
+ C C G TG +C+ + C C+ G S AT C C PG+ G
Sbjct: 457 GSFNCLCPPGYTGSRCEA--------DHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507
Query: 2051 EKCDRCPERWVLIPQEGCLECDSCTDAL 2078
+ C+ P CL C D L
Sbjct: 508 QLCEVETNECASAP---CLNHADCHDLL 532
Score = 48.4 bits (110), Expect = 5e-04
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 55/303 (18%)
Query: 1805 TVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY---------- 1854
+V PR L + P P + LS L + +C C PG+ G C++
Sbjct: 19 SVVRPRGLLCGSFPEPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLC 74
Query: 1855 -----CAA---GYYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPGSCDSINGDCL 1899
C A G+P T + C C + P S S G C
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH 134
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKN-CTACICDEFGMADCDSTTGTCVCRPGVIGEKC 1958
+ + C+ C PG+ G+ ++ C+A C G+ C C PG G C
Sbjct: 135 --IQASGRPQCS-CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
+R + + + G PC G + +T + QC C G G +C+ A
Sbjct: 192 ERDVNECFQ-DPG----PCPKGTSCHNTL---GSFQCLCPVGQEGPRCELRAGP------ 237
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQ---CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCT 2075
C C+ G + M C C PG IG C+ P+ V C +C
Sbjct: 238 --CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV---SHQCQNGGTCQ 292
Query: 2076 DAL 2078
D L
Sbjct: 293 DGL 295
Score = 48.4 bits (110), Expect = 5e-04
Identities = 91/379 (24%), Positives = 127/379 (33%), Gaps = 64/379 (16%)
Query: 406 CTCNLNGTEGEHC-TPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCD 464
CTC L G GE C + CP + C I G P+C +C G + D
Sbjct: 103 CTC-LPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG--RPQC-SCMPGWTGEQCQLRD 158
Query: 465 KLTGD-CT----CKSKYSGRTCNQCQAGYYNYPTCKPCN-C-DTSGTEP--SICDDVSG- 514
+ + C C + Y C+ C G+ + + N C G P + C + G
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 515 -QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGK---CNCLT 570
QC+C G GPRC+ R C P C G+ D C C
Sbjct: 218 FQCLCPVGQEGPRCEL-----------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 571 NFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC----DTCR 626
F G C + +P +C+S C G+ D C C + G C D C
Sbjct: 267 GFIGPDC-EVNP-----DNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSEDVDECE 319
Query: 627 EQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYN 686
Q P C + C S G C++ + I C P +
Sbjct: 320 TQ--GPPHCRNGGTCQNSAGSFHCVCVSGWGG--TSCEENLDDCIAATCAPGSTCIDRVG 375
Query: 687 PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
F C C G L C+ + C+ + G+ QC TN + G T C
Sbjct: 376 SFSC-LCPPGRTGLL-----CHLED-MCLSQPCHGDAQC----------STNPLTGSTLC 418
Query: 747 DCDIGGSIDNNCDKTTGQC 765
C G S C + +C
Sbjct: 419 LCQPGYS-GPTCHQDLDEC 436
Score = 46.8 bits (106), Expect = 0.001
Identities = 73/319 (22%), Positives = 99/319 (31%), Gaps = 58/319 (18%)
Query: 468 GDCTCKSKYSGRTC---NQCQAGYY--NYPTCKPCNCDTSGTEPSICD-DVSGQCICKAG 521
G C C + G TC + CQ N +C+ G S S C C G
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCS 581
F G RC L E C P C G S +C+C+ + G QC
Sbjct: 109 FTGERCQAKL----------EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC---- 154
Query: 582 PGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCD 641
+ D S N V+G + CHC F+G C+ R+ EC D
Sbjct: 155 ----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE--RD-------VNECFQD 201
Query: 642 PRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
P G C + C C +G C E C C+ GT
Sbjct: 202 P-GPCPKGTSCHNTLGSFQCLCPVGQEGPRC-----------ELRAGPCPPRGCSNGGTC 249
Query: 702 NSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKT 761
+ ++ C+C C+ D C C GG+ + D
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----------NCVSHQCQNGGTCQDGLDTY 298
Query: 762 TGQCHCHSRVEGRRCDQPI 780
T C C G C + +
Sbjct: 299 T--CLCPETWTGWDCSEDV 315
Score = 41.5 bits (93), Expect = 0.056
Identities = 74/329 (22%), Positives = 112/329 (34%), Gaps = 41/329 (12%)
Query: 423 GLCPCKYNYAGKSCEICEDGYYSPECKN---CECNTVGSVSYVC--DKLTGD--CTCKSK 475
G C C + G++C+ + + C+N C+ + LT CTC
Sbjct: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
Query: 476 YSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC---DQCLS 532
++G +CQA + C P C G I QC C G+ G +C D C +
Sbjct: 109 FTG---ERCQAKLED--PCPPSFCSKRG-RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 533 GYYMQ--VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDC 590
+ V + C+C P G +C D C + G C + +
Sbjct: 163 NPCVNGGVCLATYPQIQCHC-PPGFEGHACERDVN-ECFQDPG--PCPK-GTSCHNTLGS 217
Query: 591 LSCNCDVSGSIGSTCD-DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASF 649
C C V G G C+ G C + +G C E+ + C C P F
Sbjct: 218 FQCLCPV-GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF---HLCLCPP-----GF 268
Query: 650 AGCGSVPAGELCQCKDRVQGRICNDCKPLYWNL--QEYNPFGC----EQCNCNLAGTLNS 703
G + C G C D Y L + + + C ++C +
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 704 LGACNTKSG--QCVCKQHVGERQCDQCLD 730
G C +G CVC G C++ LD
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 34.7 bits (76), Expect = 6.4
Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 22/135 (16%)
Query: 1339 PCLCDFMGSTELECNTFGG-QCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAI-CDD 1396
P C+ GS NT G C C P G C A +PCH ST +
Sbjct: 443 PSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADHNECLS----QPCHPGSTCLDLLA 495
Query: 1397 NGMCICPKNVEGENCD---------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEAD 1447
C+CP +EG+ C+ C + D+ G C C P G G +CE D
Sbjct: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLP-GFSGT--RCEED 551
Query: 1448 SGKCACRENVRGRVC 1462
+C G C
Sbjct: 552 IDECRSSPCANGGQC 566
Score = 34.3 bits (75), Expect = 8.4
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 42/222 (18%)
Query: 1330 TSEYNS-GARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSA------------CRTG 1376
TS +N+ G+ CLC +G C G CP + G TC C G
Sbjct: 209 TSCHNTLGSFQCLCP-VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 1377 YYGFPNCR--PCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDC---- 1430
+ G P+C P +C S C + G C ++ C C +D D+C
Sbjct: 268 FIG-PDCEVNPDNCVSHQ-CQNGGTC--QDGLDTYTC-LCPETWTGWDCSEDVDECETQG 322
Query: 1431 --NCNPLGVVGNQLQ-----CEADSGKCACRENVRGRVCDHCVPGHYAFP--DCYQCTC- 1480
+C G N C + G +C EN+ + C PG + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1481 -NRHGTTYDVCDQNTAQ-CY----CKTN-VRGQACDTCKEEY 1515
R G + D +Q C+ C TN + G C+ Y
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
>AY764265-1|AAW47412.1| 209|Homo sapiens netrin G1 isoform G1m
protein.
Length = 209
Score = 78.2 bits (184), Expect = 5e-13
Identities = 43/140 (30%), Positives = 60/140 (42%), Gaps = 8/140 (5%)
Query: 495 KPCNCDTSGTEPSICDDVSGQ-CI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCN 549
+ C C S D ++ C+ CK G C+ C GY+ L E C+ C
Sbjct: 60 RDCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECY 119
Query: 550 CDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCD---VSGSIGSTCD 606
C+P GS C+ G C C T G +CD+C PG + C CD + G TC
Sbjct: 120 CNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCH 179
Query: 607 DNGLCHCKSNFDGAKCDTCR 626
+N C C + + G C+ R
Sbjct: 180 NNVRCLCPAAYTGILCEKLR 199
Score = 74.1 bits (174), Expect = 9e-12
Identities = 46/150 (30%), Positives = 65/150 (43%), Gaps = 18/150 (12%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C H+ C+Y ID + C++C+HNT G +C CR Y+R
Sbjct: 62 CECFGHSNRCSY---IDLLNTVI-----------CVSCKHNTRGQHCELCRLGYFRNASA 107
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN- 409
+ D+ +VC C C+P S + SG CEC+ P C C G + C+P C+
Sbjct: 108 QLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDN 167
Query: 410 --LNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
L+ G C + C C Y G CE
Sbjct: 168 ELLHCQNGGTC-HNNVRCLCPAAYTGILCE 196
Score = 67.7 bits (158), Expect = 7e-10
Identities = 50/153 (32%), Positives = 69/153 (45%), Gaps = 26/153 (16%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACP 1818
C+C GHS++C +NT IC++C NT G HCE C GY + A + C+ C C
Sbjct: 62 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC- 120
Query: 1819 MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCN 1878
P + C NGS C C+ G G +C+ C G H G C+P
Sbjct: 121 --NPLGSIHDRC----NGSGF-CECKTGTTGPKCDECLPG-------NSWHYG--CQPNV 164
Query: 1879 CSGN-INPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C ++ Q+ G+C + N CL C G C
Sbjct: 165 CDNELLHCQNGGTCHN-NVRCL-CPAAYTGILC 195
Score = 67.3 bits (157), Expect = 1e-09
Identities = 45/154 (29%), Positives = 71/154 (46%), Gaps = 18/154 (11%)
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGD-CLKCVNNTAGAACNLCAPGFYGDA--- 1921
+ + ++ + C C G+ N D +N C+ C +NT G C LC G++ +A
Sbjct: 51 SSVQVANHKRDCECFGHSNRCS--YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 108
Query: 1922 IFSKN-CTACICDEFG-MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNC 1979
+ +N C C C+ G + D + +G C C+ G G KCD C P G + GC P C
Sbjct: 109 LDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLP---GNSWHYGCQPNVC 165
Query: 1980 GIASESTQCDD-----DNGQCRCAKGVTGKQCDQ 2008
+E C + +N +C C TG C++
Sbjct: 166 D--NELLHCQNGGTCHNNVRCLCPAAYTGILCEK 197
Score = 61.7 bits (143), Expect = 5e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 15/126 (11%)
Query: 1399 MCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
+C+ C N G++C+ C+ F D + C +C CNPLG + ++ C SG C
Sbjct: 81 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR--CNG-SGFCE 137
Query: 1453 CRENVRGRVCDHCVPGHYAFPDCYQCTCNR---HGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ G CD C+PG+ C C+ H C N +C C G C+
Sbjct: 138 CKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTC-HNNVRCLCPAAYTGILCE 196
Query: 1510 --TCKE 1513
C+E
Sbjct: 197 KLRCEE 202
Score = 60.5 bits (140), Expect = 1e-07
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 14/115 (12%)
Query: 427 CKYNYAGKSCEICEDGYYSPE---------CKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
CK+N G+ CE+C GY+ C C CN +GS+ C+ +G C CK+ +
Sbjct: 85 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTT 143
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTS---GTEPSICDDVSGQCICKAGFGGPRCDQ 529
G C++C G + C+P CD C + + +C+C A + G C++
Sbjct: 144 GPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHN-NVRCLCPAAYTGILCEK 197
Score = 57.6 bits (133), Expect = 8e-07
Identities = 48/165 (29%), Positives = 66/165 (40%), Gaps = 26/165 (15%)
Query: 449 KNCEC-NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYNYPT--------CKPCN 498
++CEC SY+ T C +CK G+ C C+ GY+ + C C
Sbjct: 60 RDCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECY 119
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ G+ C+ SG C CK G GP+CD+CL G C P CD +
Sbjct: 120 CNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHY-----GCQPNVCD---NELL 170
Query: 559 SCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
C G C+ +C P Y C C+ +GS GS
Sbjct: 171 HCQNGGTCH-----NNVRC--LCPAAYTGILCEKLRCEEAGSCGS 208
Score = 54.8 bits (126), Expect = 6e-06
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 567 NCLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGSTCDDNGLCHCKSNFD 618
+C N G C+ C GY++ C+ C C+ GSI C+ +G C CK+
Sbjct: 84 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTT 143
Query: 619 GAKCDTCREQFYNYPACEECNCD 641
G KCD C + C+ CD
Sbjct: 144 GPKCDECLPGNSWHYGCQPNVCD 166
Score = 51.2 bits (117), Expect = 7e-05
Identities = 33/119 (27%), Positives = 44/119 (36%), Gaps = 11/119 (9%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCL---CDFMGSTELECNTFGGQCPCKP 1363
C S + LCR F S C+ C+ +GS CN G C CK
Sbjct: 82 CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKT 140
Query: 1364 NVIGRTCSACRTGYYGFPNCRP--C-----HCPSTAICDDNGMCICPKNVEGENCDRCK 1415
G C C G C+P C HC + C +N C+CP G C++ +
Sbjct: 141 GTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR 199
Score = 50.0 bits (114), Expect = 2e-04
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 1997 CAKGVTGKQCDQCAAGFWNYT------KDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
C G+ C+ C G++ ++ C C CN S+ CN +G CEC G G
Sbjct: 85 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTG 144
Query: 2051 EKCDRC 2056
KCD C
Sbjct: 145 PKCDEC 150
Score = 48.0 bits (109), Expect = 6e-04
Identities = 45/155 (29%), Positives = 60/155 (38%), Gaps = 34/155 (21%)
Query: 231 CMCNGHADTCEPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE 289
C C GH++ C D LN ++C C+HNT G C C G+ + +Q D C
Sbjct: 62 CECFGHSNRCSYID---LLNTVICVSCKHNTRGQHCELCRLGYFRN--ASAQLDDENVCI 116
Query: 290 PCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYG 349
C C+ + I+ R G G C C+ T G C++C P YG
Sbjct: 117 ECYCNPLGS----------------IHDRCNGSGFC-ECKTGTTGPKCDECLPGNSWHYG 159
Query: 350 KRWDELDVCQPCQCDP---HFSTGNCEEESGRCEC 381
CQP CD H G + RC C
Sbjct: 160 --------CQPNVCDNELLHCQNGGTCHNNVRCLC 186
Score = 47.2 bits (107), Expect = 0.001
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 17/128 (13%)
Query: 1944 TGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCR 1996
T CV C+ G+ C+ C ++ L+ C C C + S +C+ +G C
Sbjct: 79 TVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCE 137
Query: 1997 CAKGVTGKQCDQCAAG-FWNYTKDGCDHCNCNTGY---SVGFMCNATGQCECLPGVIGEK 2052
C G TG +CD+C G W+Y GC C+ G C+ +C C G
Sbjct: 138 CKTGTTGPKCDECLPGNSWHY---GCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGIL 194
Query: 2053 CD--RCPE 2058
C+ RC E
Sbjct: 195 CEKLRCEE 202
Score = 46.4 bits (105), Expect = 0.002
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 15/122 (12%)
Query: 663 CKDRVQGRICNDCKPLYW---NLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
CK +G+ C C+ Y+ + Q + C +C CN G+++ CN SG C CK
Sbjct: 85 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD--RCNG-SGFCECKTG 141
Query: 720 VGERQCDQCLDG---FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+CD+CL G Y Q N V C GG+ NN +C C + G C
Sbjct: 142 TTGPKCDECLPGNSWHYGCQPN-VCDNELLHCQNGGTCHNNV-----RCLCPAAYTGILC 195
Query: 777 DQ 778
++
Sbjct: 196 EK 197
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 16/100 (16%)
Query: 1361 CKPNVIGRTCSACRTGYYGFPN--------CRPCHC-PSTAI---CDDNGMCICPKNVEG 1408
CK N G+ C CR GY+ + C C+C P +I C+ +G C C G
Sbjct: 85 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTG 144
Query: 1409 ENCDRCKP-YTFNFDVQRG-CDD--CNCNPLGVVGNQLQC 1444
CD C P ++++ Q CD+ +C G N ++C
Sbjct: 145 PKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRC 184
Score = 41.9 bits (94), Expect = 0.042
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 1478 CTCNRHGTTYDVCDQ-NTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFC 1531
C C H D NT C CK N RGQ C+ C+ YF + Q D+ + C +C+C
Sbjct: 62 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC 120
Score = 39.9 bits (89), Expect = 0.17
Identities = 28/114 (24%), Positives = 42/114 (36%), Gaps = 12/114 (10%)
Query: 381 CRPEFQPPDCSSCAYGYF--------DYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYA 432
C+ + C C GYF D C C CN G+ + C + G C CK
Sbjct: 85 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGS-GFCECKTGTT 143
Query: 433 GKSCEICEDG---YYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQ 483
G C+ C G +Y + C+ + + C C + Y+G C +
Sbjct: 144 GPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 197
Score = 39.5 bits (88), Expect = 0.22
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 11/71 (15%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG CE C G++R S C+ C CN D+C+ +G C C T
Sbjct: 85 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN-GSGFC-ECKTGT 142
Query: 1789 IGDHCEFCMSG 1799
G C+ C+ G
Sbjct: 143 TGPKCDECLPG 153
Score = 37.1 bits (82), Expect = 1.2
Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 22/114 (19%)
Query: 613 CKSNFDGAKCDTCREQFYNYPA--------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
CK N G C+ CR ++ + C EC C+P G + C C+CK
Sbjct: 85 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLG--SIHDRCNG---SGFCECK 139
Query: 665 DRVQGRICNDCKPLYWNLQEYNPFGCEQ--CNCNLAGTLNSLGACNTKSGQCVC 716
G C++C P N Y GC+ C+ L N G C+ + +C+C
Sbjct: 140 TGTTGPKCDECLP--GNSWHY---GCQPNVCDNELLHCQNG-GTCH-NNVRCLC 186
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 78.2 bits (184), Expect = 5e-13
Identities = 114/445 (25%), Positives = 158/445 (35%), Gaps = 67/445 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C P FS +CEE+ C P C D N C C L G G+ C
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSC-------MDGVNTFSCLC-LPGFTGDKCQT 948
Query: 421 TDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
C PCK G +C + Y C+C G C+ +CT S ++
Sbjct: 949 DMNECLSEPCK---NGGTCSDYVNSY------TCKCQ-AGFDGVHCENNINECTESSCFN 998
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI----CKAGFGGPRCDQCLSG 533
G TC G ++ P S I + S C+ C G G RC C G
Sbjct: 999 GGTCVD---GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLG 1054
Query: 534 YY-MQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Y C C G T A+ +C C + + GA CD P +
Sbjct: 1055 YTGKNCQTLVNLCSRSPCKNKG-TCVQKKAESQCLCPSGWAGAYCD--------VP---N 1102
Query: 593 CNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGV 645
+CD++ S + C +G+C N +C Y +EC +P G
Sbjct: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGA 1162
Query: 646 TAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
T S F G C VP + C+ V C+ + N F C C G L
Sbjct: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC-SCPPGTRGLL 1221
Query: 702 --NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSI 754
++ C + C+ C +G C +CL GF + D+ C C GS+
Sbjct: 1222 CEENIDDC-ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 755 DNNCDKTTGQ--CHCHSRVEGRRCD 777
D C + T C C S GR C+
Sbjct: 1280 D--CIQLTNDYLCVCRSAFTGRHCE 1302
Score = 75.8 bits (178), Expect = 3e-12
Identities = 133/575 (23%), Positives = 192/575 (33%), Gaps = 78/575 (13%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C+C G C + + Q D C C+ +IDE S
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 314 DIN-GR---YEGGGKCLNCQHNTEGINCN-KCRPTYYRP--YGKRWDELDVCQPCQCDPH 366
+N GR G +C NCQ T G+NC P +G D ++ C C P
Sbjct: 616 CLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS-CVCSPG 673
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----DYPNCKPCTCNLNGTEGEHCTP-- 420
F+ C + C P + C + G+ + P+ C +N C
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Query: 421 -TDGL----CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
T GL C C + G +CE+ ++ EC + C G+ CD L CTCK
Sbjct: 734 CTGGLSGYKCLCDAGWVGINCEVDKN-----ECLSNPCQNGGT----CDNLVNGYRCTCK 784
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLS 532
+ G C N C C GT DD+SG C C + G C L+
Sbjct: 785 KGFKGYNCQ------VNIDECASNPCLNQGT---CFDDISGYTCHCVLPYTGKNCQTVLA 835
Query: 533 GYYMQVLGRERQC--------VPCNCDPTGSTSTSCSAD-GKC---NCLT-----NFGGA 575
C C C P G C+ D +C C+ N G+
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAP-GWQGQRCTIDIDECISKPCMNHGLCHNTQGS 894
Query: 576 QCDQCSPGYY------KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
+C PG+ DCL+ C GS + C C F G KC T +
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS-CLCLPGFTGDKCQTDMNEC 953
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ P C V + C + G C++ + + C + N F
Sbjct: 954 LSEPCKNGGTCSDY-VNSYTCKCQAGFDG--VHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 690 CEQCNCNLAGT--LNSLGACNTKS--GQCVCKQHVGERQCDQCLDGFYRLQTNDVFG-CT 744
C C G+ L+ + C++ + C +G +C C G+ + C+
Sbjct: 1011 C-LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCS 1068
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C G+ K QC C S G CD P
Sbjct: 1069 RSPCKNKGTCVQK--KAESQCLCPSGWAGAYCDVP 1101
Score = 71.7 bits (168), Expect = 5e-11
Identities = 137/575 (23%), Positives = 199/575 (34%), Gaps = 103/575 (17%)
Query: 254 CRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
C CQ G +C + C S + ++FSC+ C T + +++E
Sbjct: 131 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK---CLTGFTGQKCETDVNE-- 185
Query: 311 LSLDINGRYEGGGKCLN--------CQHNTEGINCNK----CRPTYYRPYGKRWDELDVC 358
DI G + GG CLN C G C+ C P+ G D
Sbjct: 186 --CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG---TEG 415
C C P F CE C P + + C G Y NC+ C G TE
Sbjct: 244 FECNCLPGFEGSTCERNIDDC---PNHRCQNGGVCVDGVNTY-NCR-CPPQWTGQFCTED 298
Query: 416 -EHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECK----NCECNTVGSVSYVCDKL 466
+ C C C G C +C +G+ +C +C + S D++
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGC-VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 467 TG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
C C +G C+ A N P K CDT + ++GQ C C G+
Sbjct: 358 ASFSCMCPEGKAGLLCHLDDACISN-PCHKGALCDT--------NPLNGQYICTCPQGYK 408
Query: 524 GPRC----DQCL---------SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSAD 563
G C D+C +G + G +C+ C D S C D
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD 623
CL GG C C PG+ + C +++ + C +NG C K N +C
Sbjct: 469 --ATCLDKIGGFTC-LCMPGF----KGVHCELEINECQSNPCVNNGQCVDKVN--RFQC- 518
Query: 624 TCREQFYNYPAC----EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
C F P C ++C+ P + A C P G CQC G +C +
Sbjct: 519 LCPPGFTG-PVCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEE----- 569
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL-DGFYRLQTN 738
N+ +P C C G + CN +C + E CL DG +
Sbjct: 570 -NIDNCDPDPCHHGQCQ-DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDG----RCI 623
Query: 739 DVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
D+ +C+C G S NC+ C + + G
Sbjct: 624 DLVNGYQCNCQPGTS-GVNCEINFDDCASNPCIHG 657
Score = 67.7 bits (158), Expect = 7e-10
Identities = 99/380 (26%), Positives = 134/380 (35%), Gaps = 77/380 (20%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCV------PCQC-NGHSD-QCDVNTGICLNC 1784
C CP Y G +C+ R P G CV C C +G + CDV C +
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DI 1107
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNC 1843
A + G E H + + C CP+ Y + D + N C
Sbjct: 1108 AASRRGVLVEHLCQ--HSGVCINA-GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYC--KPC----NCSGNIN----PQDPGS--- 1890
GG RCE C GY G+ + ++ D C +PC C +N PG+
Sbjct: 1165 SDFIGGYRCE-CVPGYQGVNCEYEV---DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL 1220
Query: 1891 -CDSINGDCLK---------CVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMA 1938
C+ DC + C++ G +C C PGF G+ C + C G
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCR-CLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 1939 DCDSTTG--TCVCRPGVIGEKCDR---CAPDHWGLNTGLGCTP--------CNCGIASES 1985
DC T CVCR G C+ P LN G C C
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAG---FWNYTKD---GCDHCNCNTGYSVGFMCNAT 2039
+C GQ +C K G+QC A+G F +D GC C G S C+
Sbjct: 1340 ARCQSSCGQVKCRK---GEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGS----CHPQ 1392
Query: 2040 GQ-----CECLPGVIGEKCD 2054
Q C+C P G +C+
Sbjct: 1393 RQPPYYSCQCAPPFSGSRCE 1412
Score = 66.1 bits (154), Expect = 2e-09
Identities = 137/570 (24%), Positives = 193/570 (33%), Gaps = 96/570 (16%)
Query: 258 HNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC----NCHN--HTTECTYDPEIDEKRL 311
HNT G +C GF ++ D PC +C + +T C P +
Sbjct: 889 HNTQGSYMCECPPGFSGMD--CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Query: 312 SLDINGRY----EGGGKCLN--------CQHNTEGINC----NKCRPTYYRPYGKRWDEL 355
D+N + GG C + CQ +G++C N+C + G D +
Sbjct: 947 QTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI 1006
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEG 415
+ C C F+ C E C P +C G Y C+C L G G
Sbjct: 1007 NSFS-CLCPVGFTGSFCLHEINECSSHPCLNE---GTCVDGLGTYR----CSCPL-GYTG 1057
Query: 416 EHCTPTDGLC---PCKYN--YAGKSCE---ICEDGYYSPECK--NCECNTVGSVSYVCDK 465
++C LC PCK K E +C G+ C N C+ S V
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV- 1116
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC----ICKAG 521
+ C+ +SG N AG +Y C P S E + + S C C
Sbjct: 1117 ---EHLCQ--HSGVCIN---AGNTHYCQC-PLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNFGGAQCDQ 579
GG RC+ C+ GY Q + E + C P G T KC+C G C++
Sbjct: 1168 IGGYRCE-CVPGY--QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 1224
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDN--GL-CHCKSNFDGAKCDTCREQFYNYPACE 636
+ P CL+ G C D G C C F G +C+ + + P
Sbjct: 1225 NIDDCARGPHCLN---------GGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 637 ECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
E + D C + LC C+ GR C + + N C +
Sbjct: 1276 EGSLD----------CIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
Query: 697 LAGTL-----NSLGA-CNTKSGQCVCKQHVGERQCDQCLDG---FYRLQTNDVFGCTECD 747
G + GA C + GQ C++ GE QC G F + GC
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVKCRK--GE-QCVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 748 CDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C GGS C C G RC+
Sbjct: 1383 CQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
Score = 64.9 bits (151), Expect = 5e-09
Identities = 115/482 (23%), Positives = 161/482 (33%), Gaps = 65/482 (13%)
Query: 325 CLNCQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
CLN +G+ +C P Y GK L C P + G C ++ +C
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYT--GKNCQTL--VNLCSRSPCKNKGTCVQKKAESQC-- 1087
Query: 384 EFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P S A Y D PN + G EH G+C N C + G
Sbjct: 1088 -LCP---SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Query: 443 YYSPE-CKNCECNTVGSVSYVCDKLTG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCD 500
Y E C N + D + G C C Y G C Y C+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE------YEVDECQNQPCQ 1197
Query: 501 TSGTEPSICDDVSG--QCICKAGFGGPRCDQ----------CLSGYYM--QVLGRERQCV 546
GT C D+ +C C G G C++ CL+G ++ G +C+
Sbjct: 1198 NGGT----CIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCL 1253
Query: 547 P------CNCDPTGSTSTSCSADGKCNC--LTNFGGAQCDQCSPGYY--KYPD-CLSCNC 595
P C D S CS++G +C LTN C G + + D C C
Sbjct: 1254 PGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPC 1313
Query: 596 DVSGS--IGSTCDDNGLCHCKSNFDGAKC-DTCRE-QFYNYPACEECNCDPRGVTASFAG 651
G+ + S D +C C F GA+C +C + + C PR S
Sbjct: 1314 LNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 652 CGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNT- 709
C S A CQ G C+ +P Y++ Q PF +C A C +
Sbjct: 1374 CESGCASSPCQ-----HGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 710 ----KSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
K+ VC + C Q G L + + I+N CD+
Sbjct: 1429 YCADKARDGVCDEACNSHAC-QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV 1487
Query: 766 HC 767
C
Sbjct: 1488 EC 1489
Score = 64.5 bits (150), Expect = 7e-09
Identities = 112/468 (23%), Positives = 162/468 (34%), Gaps = 84/468 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSS--------CAYGY------FDYPNCKPC 406
C C P F +CE E C+ P C C G+ D +C
Sbjct: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 407 TCNLNGTEG-EHCTPTDGLCPCKYNYAGKSCE----ICE-DGYYSPECKN------CECN 454
C LNG + +H P C C + G CE C+ D + +C++ C CN
Sbjct: 540 PC-LNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN 596
Query: 455 TVGSVSYVCDKLTGDC---------TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE 505
G + +C +C C +G CN CQ G C+ N D +
Sbjct: 597 P-GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN-CQPGTSGV-NCE-INFDDCASN 652
Query: 506 P---SICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTG 554
P IC D + C+C GF G RC+ + + C+ C C P G
Sbjct: 653 PCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCIC-PEG 711
Query: 555 STSTSC-SADGKC--------NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC 605
SC S +C NC G +C C G+ ++C D + + + C
Sbjct: 712 PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC-LCDAGWVG----INCEVDKNECLSNPC 766
Query: 606 DDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQ 662
+ G C N G +C TC++ F Y +EC +P + C +G C
Sbjct: 767 QNGGTCDNLVN--GYRC-TCKKGFKGYNCQVNIDECASNP---CLNQGTCFDDISGYTCH 820
Query: 663 CKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG----ACNTKSGQCVCK 717
C G+ C P N E E N L + G C +C+ K
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 718 QHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
+ C G Y + F +C+ DI + N C + G C
Sbjct: 881 PCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPC-QNGGSC 926
Score = 62.9 bits (146), Expect = 2e-08
Identities = 96/400 (24%), Positives = 132/400 (33%), Gaps = 78/400 (19%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
P C GY N C NGT G C C + G+ C+ +
Sbjct: 22 PAHALQCRDGYEPCVNEGMCVTYHNGT---------GYCKCPEGFLGEYCQ------HRD 66
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC----NCDTS 502
C+ C G+ V + G TC+ SG T CQ Y T PC C
Sbjct: 67 PCEKNRCQNGGTC--VAQAMLGKATCRCA-SGFTGEDCQ-----YSTSHPCFVSRPCLNG 118
Query: 503 GTEPSICDDVSGQCICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
GT + D +C C+ GF G C D CLS PC GST T+
Sbjct: 119 GTCHMLSRDTY-ECTCQVGFTGKECQWTDACLSH-------------PC---ANGSTCTT 161
Query: 560 CSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC---DDNGLCHCKSN 616
+ C CLT F G +C+ D C+ G TC + C C
Sbjct: 162 VANQFSCKCLTGFTGQKCE---------TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 617 FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCK 676
F G CD+ P C G +F C +P E C+ + + C+
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTG-DFTFE-CNCLPGFEGSTCERNIDDCPNHRCQ 270
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ 736
+ N + C +C G C +C+ Q + C +G
Sbjct: 271 NGGVCVDGVNTYNC-RCPPQWTGQF-----CTEDVDECLL-------QPNACQNGGTCAN 317
Query: 737 TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
N +GC C + G ++C + C S G C
Sbjct: 318 RNGGYGCV-C---VNGWSGDDCSENIDDCAFASCTPGSTC 353
Score = 62.1 bits (144), Expect = 4e-08
Identities = 90/342 (26%), Positives = 125/342 (36%), Gaps = 64/342 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC G +C+ G+ GF C + D+C N CLN C D+ G
Sbjct: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGF-KGYNCQVNIDECASNP--CLNQGTCFDDISG 816
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C C+ Y G ++C P P P N A+ C S N +C C PG+ G
Sbjct: 817 YTCH-CVLPYTG-------KNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQG 867
Query: 1850 ARC----EYCAAG---YYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--- 1899
RC + C + +G+ +T G Y C C + D C+ DCL
Sbjct: 868 QRCTIDIDECISKPCMNHGLCHNTQ---GSYM--CECPPGFSGMD---CEEDIDDCLANP 919
Query: 1900 -----KCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGTCVCRPG 1952
C++ +C LC PGF GD + C + C G + TC C+ G
Sbjct: 920 CQNGGSCMDGVNTFSC-LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAA 2011
G C+ +N CT +C + T D N C C G TG C
Sbjct: 979 FDGVHCEN------NINE---CTESSC--FNGGTCVDGINSFSCLCPVGFTGSFC----- 1022
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+ + H N G V + T +C C G G+ C
Sbjct: 1023 --LHEINECSSHPCLNEGTCVDGL--GTYRCSCPLGYTGKNC 1060
Score = 61.7 bits (143), Expect = 5e-08
Identities = 99/429 (23%), Positives = 150/429 (34%), Gaps = 74/429 (17%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYAGKSC 436
C C ++ DC+ D C N G+ C TDG C C YAG C
Sbjct: 401 CTCPQGYKGADCTE------DVDECAMANSNPCEHAGK-CVNTDGAFHCECLKGYAGPRC 453
Query: 437 EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
E+ + +S C+N D TC K G TC C G+
Sbjct: 454 EMDINECHSDPCQN------------------DATCLDKIGGFTC-LCMPGFKGV----H 490
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C + + + + C + +GQC+ K C +G Q+ + PC G+
Sbjct: 491 CELEINECQSNPCVN-NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC---LNGAK 546
Query: 557 STSCSADGKCNCLTNFGGAQC----DQCSPGYYKYPDC------LSCNCDVSGSIGSTCD 606
+C C T F G C D C P + C +C C+ G +G+ C
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN-PGYMGAICS 605
Query: 607 DN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTA--SFAGCGSVPAGELC 661
D C+ + +C + +CNC P GV +F C S P
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGY-------QCNCQPGTSGVNCEINFDDCASNPCIHGI 658
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG-QCVCKQHV 720
C D + C C P + Q N ++C N N +G +C+C +
Sbjct: 659 -CMDGINRYSC-VCSPGFTG-QRCN-IDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
Query: 721 GERQC----DQCLDG--FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
C ++CL + T + G +C CD G + NC+ +C + G
Sbjct: 713 HHPSCYSQVNECLSNPCIHGNCTGGLSG-YKCLCD-AGWVGINCEVDKNECLSNPCQNGG 770
Query: 775 RCDQPIRAH 783
CD + +
Sbjct: 771 TCDNLVNGY 779
Score = 61.3 bits (142), Expect = 6e-08
Identities = 86/344 (25%), Positives = 114/344 (33%), Gaps = 42/344 (12%)
Query: 1733 VEECQC-PRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
+ ECQ P G ++ P GF P C D C CLN C D+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPV-CQIDIDDCSSTP--CLNGAKCIDHP 551
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C +G+ G +C P P ++ + +C C PGY
Sbjct: 552 NGYECQ-CATGFTGVLCEENIDNC------DPDPCHHGQCQDGIDS----YTCICNPGYM 600
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK--PCNC----SG---NINPQDPGSCDSINGDCL 1899
GA C Y P D D CNC SG IN D S I+G C+
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TCVCRPGVIGE 1956
+N + C +C+PGF G I C + C + G + G C+C G
Sbjct: 661 DGINRYS---C-VCSPGFTGQRCNIDIDECASNPCRK-GATCINGVNGFRCICPEGPHHP 715
Query: 1957 KC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
C + C + H GL C C C+ D +C G CD
Sbjct: 716 SCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL 775
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G+ K G NC Q C + G C
Sbjct: 776 VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
Score = 60.1 bits (139), Expect = 1e-07
Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 46/304 (15%)
Query: 1784 CADNTI-GDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C N + G + C GY G D T D CA P + A C ++ +G+ C
Sbjct: 390 CDTNPLNGQYICTCPQGYKGADCT----EDVDECAMANSNPCEH-AGKC-VNTDGAF-HC 442
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGD-------YCKP----CNCSGNINPQDPGS 1890
C GY G RCE + P D D C P +C IN
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TC 1947
C + NG C+ VN C LC PGF G I +C++ C G D G C
Sbjct: 503 CVN-NGQCVDKVNRFQ---C-LCPPGFTGPVCQIDIDDCSSTPCLN-GAKCIDHPNGYEC 556
Query: 1948 VCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C G G C D C PD H G+ C C C D +C +
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYS--------VGFMCNATGQ--CECLPGVIG 2050
+ +C G+ + G NC + G + + C C PG G
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 2051 EKCD 2054
++C+
Sbjct: 677 QRCN 680
Score = 57.2 bits (132), Expect = 1e-06
Identities = 87/351 (24%), Positives = 120/351 (34%), Gaps = 57/351 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC C + G C Q + P C + C TG + + + C+
Sbjct: 130 ECTCQVGFTGKEC-QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE-CD 187
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPS---NNFALSCDLSE--NGSL--------ISC 1841
HG + P C CP + ++ + C S NG C
Sbjct: 188 IPGHCQHGGTCLNLPGSYQ-CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 1842 NCQPGYGGARCE---------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
NC PG+ G+ CE C G G+ D ++T + P +G +D C
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNG--GVCVD-GVNTYNCRCPPQWTGQFCTEDVDECL 303
Query: 1893 SINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C C N G C +C G+ GD +C+ I D+ A C + TC+
Sbjct: 304 LQPNACQNGGTCANRNGGYGC-VCVNGWSGD-----DCSENI-DDCAFASC-TPGSTCID 355
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRCAKGVTGKQ 2005
R V C C GL L C + CD + NGQ C C +G G
Sbjct: 356 R--VASFSC-MCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGAD 411
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATG--QCECLPGVIGEKCD 2054
C + D C N N G N G CECL G G +C+
Sbjct: 412 CTE--------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
Score = 56.8 bits (131), Expect = 1e-06
Identities = 92/387 (23%), Positives = 131/387 (33%), Gaps = 62/387 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + Y G CE + C C + D G C G HCE
Sbjct: 442 CECLKGYAGPRCE--------MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
Query: 1796 CMSGYHGDATVGTPR-----DCLICACPMPYPSNNFALSC-DLSENGSLISCNCQPGYGG 1849
++ + V + + C CP + + D S L C G
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG 553
Query: 1850 ARCEYCAAGYYGI--PEDTDLHTGDYCKPCNCSGNINPQ----DPGSCDSINGD------ 1897
C+ CA G+ G+ E+ D D C C I+ +PG +I D
Sbjct: 554 YECQ-CATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 1898 ---CL---KCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
CL +C++ G CN C PG G I +C + C G+ +CVC
Sbjct: 613 SSPCLNDGRCIDLVNGYQCN-CQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVC 670
Query: 1950 RPGVIGEKC----DRCA--PDHWGLN--TGLGCTPCNCGIASESTQCDDDNGQC------ 1995
PG G++C D CA P G G+ C C C +C
Sbjct: 671 SPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 1996 --RCAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVI 2049
C G++G +C C AG+ K+ C C G + + N +C C G
Sbjct: 731 HGNCTGGLSGYKC-LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY-RCTCKKGFK 788
Query: 2050 GEKCDRCPERWVLIPQEGCLECDSCTD 2076
G C + P CL +C D
Sbjct: 789 GYNCQVNIDECASNP---CLNQGTCFD 812
Score = 52.4 bits (120), Expect = 3e-05
Identities = 93/374 (24%), Positives = 125/374 (33%), Gaps = 67/374 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G C ++ + PC +G D+ G NC T G +CE
Sbjct: 593 CICNPGYMGAICSD------QIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVNCEI 644
Query: 1796 ----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C S HG G R +C+ N + + + N C G G
Sbjct: 645 NFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID-ECASNPCRKGATCINGVNG 703
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPC---NCSGNINPQ----DPG----SCDSINGDC 1898
RC C G + P PC NC+G ++ D G +C+ +C
Sbjct: 704 FRC-ICPEGPHH-PSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
Query: 1899 LK--------CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
L C N G C C GF G NC I DE C GTC
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCT-CKKGFKG-----YNCQVNI-DECASNPC-LNQGTCF-- 811
Query: 1951 PGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----DNGQCRCAKGVTGKQC 2006
+ G C C + G N PC+ + C + ++ C CA G G++C
Sbjct: 812 DDISGYTC-HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Query: 2007 DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCDRCPERWVLIP 2064
T D D C + G N G CEC PG G C+ + + P
Sbjct: 871 ----------TID-IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 2065 QEGCLECDSCTDAL 2078
C SC D +
Sbjct: 920 ---CQNGGSCMDGV 930
Score = 48.0 bits (109), Expect = 6e-04
Identities = 73/295 (24%), Positives = 108/295 (36%), Gaps = 67/295 (22%)
Query: 1766 QCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNN 1825
QC + C VN G+C+ + T +C+ C G+ G+ C P N
Sbjct: 27 QCRDGYEPC-VNEGMCVTYHNGT--GYCK-CPEGFLGE----------YCQHRDPCEKNR 72
Query: 1826 FALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC---KPCNCSGN 1882
C +NG +C Q G A C CA+G+ G ED T C +PC
Sbjct: 73 ----C---QNGG--TCVAQAMLGKATCR-CASGFTG--EDCQYSTSHPCFVSRPC----- 115
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTACICDEFGMADCD 1941
+ G+C ++ D +C C GF G + ++ C + C
Sbjct: 116 ---LNGGTCHMLSRDTYECT----------CQVGFTGKECQWTDACLSHPCANGSTCTTV 162
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKG 2000
+ +C C G G+KC+ + C P +C QC+C +G
Sbjct: 163 ANQFSCKCLTGFTGQKCETDVNE---------CDIPGHCQHGGTCLNLPGSY-QCQCPQG 212
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
TG+ CD Y C C G + + T +C CLPG G C+R
Sbjct: 213 FTGQYCDSL------YVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 27/149 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNC--RPCHCPSTAICDDNGM-CICPKNVEGENC-DRC 1414
C C P G+ C+ C PC +T I NG CICP+ +C +
Sbjct: 668 CVCSPGFTGQRCNI------DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Query: 1415 KPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
N + C C C+ G VG + CE D +C G CD+ V G
Sbjct: 722 NECLSNPCIHGNCTGGLSGYKCLCDA-GWVG--INCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Y+CTC + Y+ C N +C
Sbjct: 779 -------YRCTCKKGFKGYN-CQVNIDEC 799
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/181 (25%), Positives = 62/181 (34%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCR--PCHCP 1389
C C +G T C +C P G TCS C GY G NC C
Sbjct: 1135 CQCP-LGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGV-NCEYEVDECQ 1192
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
+ C + G CI V C C P T + DDC P + G Q
Sbjct: 1193 NQP-CQNGGTCI--DLVNHFKCS-CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C C G C+ + +C C+ G+ + N C C++ G+ C+
Sbjct: 1249 SCRCLPGFAGERCEGDI------NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Query: 1510 T 1510
T
Sbjct: 1303 T 1303
Score = 44.0 bits (99), Expect = 0.010
Identities = 47/191 (24%), Positives = 69/191 (36%), Gaps = 16/191 (8%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPC--HCPSTAICDDNGMCICPKNVEGENCDRCKP 1416
C PN TC C G+ G C C S C ++G+C N +G C P
Sbjct: 848 CKESPNFESYTC-LCAPGWQG-QRCTIDIDECISKP-CMNHGLC---HNTQGSYMCECPP 901
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
D + DDC NP G+ + ++ C C G C + + P
Sbjct: 902 GFSGMDCEEDIDDCLANPCQNGGSCMD-GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
Query: 1477 QCTCNRHGTTYDV-CDQNTAQCYCKTNVR---GQAC---DTCKEEYFNLQDDNPDGCTKC 1529
TC+ + +Y C +C+ N+ +C TC + + P G T
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS 1020
Query: 1530 FCFGKTTRCSS 1540
FC + CSS
Sbjct: 1021 FCLHEINECSS 1031
Score = 41.5 bits (93), Expect = 0.056
Identities = 51/184 (27%), Positives = 66/184 (35%), Gaps = 26/184 (14%)
Query: 1336 GARPCLC--DFMG-STELECNTFGGQCPCKPN-----VIGRTCSACRTGYYGFPNCRPC- 1386
G CLC F G ELE N PC N + R C G+ G P C+
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQCVDKVNRFQCLCPPGFTG-PVCQIDI 533
Query: 1387 -HCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C ST C + CI N G C +T + D+C+ +P Q Q
Sbjct: 534 DDCSSTP-CLNGAKCIDHPN--GYECQCATGFT-GVLCEENIDNCDPDPCH--HGQCQDG 587
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRG 1505
DS C C G +C + +CY C G D+ N QC C+ G
Sbjct: 588 IDSYTCICNPGYMGAICSDQI------DECYSSPCLNDGRCIDLV--NGYQCNCQPGTSG 639
Query: 1506 QACD 1509
C+
Sbjct: 640 VNCE 643
Score = 40.3 bits (90), Expect = 0.13
Identities = 58/228 (25%), Positives = 75/228 (32%), Gaps = 28/228 (12%)
Query: 1757 LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICA 1816
+P GF C +C + G + C G+ C SG +PRDC
Sbjct: 1325 MPDGFICRCPPGFSGARCQSSCGQ-VKCRK---GEQCVHTASGPR--CFCPSPRDCESGC 1378
Query: 1817 CPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
P SC SC C P + G+RCE A P T L YC
Sbjct: 1379 ASSPCQHGG---SCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCL--SQYCAD 1432
Query: 1877 CNCSGNINPQ-DPGSCDSINGDC-LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICD 1933
G + + +C GDC L N A + L C N C+ D
Sbjct: 1433 KARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFD 1492
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN-TGLGCTPCNCG 1980
F +C + TC K D+ DH+ N GC CG
Sbjct: 1493 NF---ECQGNSKTC---------KYDKYCADHFKDNHCDQGCNSEECG 1528
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/212 (21%), Positives = 73/212 (34%), Gaps = 14/212 (6%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEG 415
C+C P FS C+ G+ +CR Q +S + P C C G+
Sbjct: 1331 CRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
Query: 416 EHCTPTDGLCPCKYNYAGKSCEICEDGYYSP--ECKNCECNTVGSVSYVCDKLTGDCTCK 473
P C C ++G CE+ +P C + C VCD+ C
Sbjct: 1391 PQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKAR-DGVCDEACNSHAC- 1448
Query: 474 SKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
++ G C+ + + N + PC + +C+ V +C+ C
Sbjct: 1449 -QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV--ECLFDNFECQGNSKTCKY 1505
Query: 533 GYYMQVLGRERQC-VPCNCDPTGSTSTSCSAD 563
Y ++ C CN + G C+AD
Sbjct: 1506 DKYCADHFKDNHCDQGCNSEECGWDGLDCAAD 1537
Score = 35.5 bits (78), Expect = 3.6
Identities = 51/216 (23%), Positives = 74/216 (34%), Gaps = 30/216 (13%)
Query: 1301 REFIEQCASYNYYIS-PNETGLCREAMFSITSEYNSGARPC---LCDFMGSTELECNTFG 1356
R+ E C + ++ N TG C+ EY PC C G+ +
Sbjct: 29 RDGYEPCVNEGMCVTYHNGTGYCK-CPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 87
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA--ICDDNGMCICPKNVEGENCDRC 1414
C C G C T + F + RPC T + D C C G+ C
Sbjct: 88 ATCRCASGFTGEDCQYS-TSHPCFVS-RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-- 143
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD 1474
+T + + C N + V NQ C+ +G + CD +PGH
Sbjct: 144 --WT-DACLSHPC--ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD--IPGH----- 191
Query: 1475 CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C GT ++ + QC C GQ CD+
Sbjct: 192 -----CQHGGTCLNL--PGSYQCQCPQGFTGQYCDS 220
Score = 35.1 bits (77), Expect = 4.8
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 21/226 (9%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRPCHCPST 1391
CLC G T +C T +C +P G TCS C+ G+ G + +
Sbjct: 935 CLC-LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
Query: 1392 AICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG-- 1449
+ C + G C+ + +C +T +F + ++C+ +P N+ C G
Sbjct: 994 SSCFNGGTCV--DGINSFSCLCPVGFTGSFCLHE-INECSSHP---CLNEGTCVDGLGTY 1047
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTC-NRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C+C G+ C V P + TC + + +C A YC +V +C
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC--DVPNVSC 1105
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSY-YTWAAIDEMVD 1553
D L + C G T C YT + +E +D
Sbjct: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 78.2 bits (184), Expect = 5e-13
Identities = 114/445 (25%), Positives = 158/445 (35%), Gaps = 67/445 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C P FS +CEE+ C P C D N C C L G G+ C
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSC-------MDGVNTFSCLC-LPGFTGDKCQT 948
Query: 421 TDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
C PCK G +C + Y C+C G C+ +CT S ++
Sbjct: 949 DMNECLSEPCK---NGGTCSDYVNSY------TCKCQ-AGFDGVHCENNINECTESSCFN 998
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI----CKAGFGGPRCDQCLSG 533
G TC G ++ P S I + S C+ C G G RC C G
Sbjct: 999 GGTCVD---GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLG 1054
Query: 534 YY-MQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Y C C G T A+ +C C + + GA CD P +
Sbjct: 1055 YTGKNCQTLVNLCSRSPCKNKG-TCVQKKAESQCLCPSGWAGAYCD--------VP---N 1102
Query: 593 CNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGV 645
+CD++ S + C +G+C N +C Y +EC +P G
Sbjct: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGA 1162
Query: 646 TAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
T S F G C VP + C+ V C+ + N F C C G L
Sbjct: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC-SCPPGTRGLL 1221
Query: 702 --NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSI 754
++ C + C+ C +G C +CL GF + D+ C C GS+
Sbjct: 1222 CEENIDDC-ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 755 DNNCDKTTGQ--CHCHSRVEGRRCD 777
D C + T C C S GR C+
Sbjct: 1280 D--CIQLTNDYLCVCRSAFTGRHCE 1302
Score = 75.8 bits (178), Expect = 3e-12
Identities = 133/575 (23%), Positives = 192/575 (33%), Gaps = 78/575 (13%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C+C G C + + Q D C C+ +IDE S
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 314 DIN-GR---YEGGGKCLNCQHNTEGINCN-KCRPTYYRP--YGKRWDELDVCQPCQCDPH 366
+N GR G +C NCQ T G+NC P +G D ++ C C P
Sbjct: 616 CLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS-CVCSPG 673
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----DYPNCKPCTCNLNGTEGEHCTP-- 420
F+ C + C P + C + G+ + P+ C +N C
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Query: 421 -TDGL----CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
T GL C C + G +CE+ ++ EC + C G+ CD L CTCK
Sbjct: 734 CTGGLSGYKCLCDAGWVGINCEVDKN-----ECLSNPCQNGGT----CDNLVNGYRCTCK 784
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLS 532
+ G C N C C GT DD+SG C C + G C L+
Sbjct: 785 KGFKGYNCQ------VNIDECASNPCLNQGT---CFDDISGYTCHCVLPYTGKNCQTVLA 835
Query: 533 GYYMQVLGRERQC--------VPCNCDPTGSTSTSCSAD-GKC---NCLT-----NFGGA 575
C C C P G C+ D +C C+ N G+
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAP-GWQGQRCTIDIDECISKPCMNHGLCHNTQGS 894
Query: 576 QCDQCSPGYY------KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
+C PG+ DCL+ C GS + C C F G KC T +
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS-CLCLPGFTGDKCQTDMNEC 953
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ P C V + C + G C++ + + C + N F
Sbjct: 954 LSEPCKNGGTCSDY-VNSYTCKCQAGFDG--VHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 690 CEQCNCNLAGT--LNSLGACNTKS--GQCVCKQHVGERQCDQCLDGFYRLQTNDVFG-CT 744
C C G+ L+ + C++ + C +G +C C G+ + C+
Sbjct: 1011 C-LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCS 1068
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C G+ K QC C S G CD P
Sbjct: 1069 RSPCKNKGTCVQK--KAESQCLCPSGWAGAYCDVP 1101
Score = 71.7 bits (168), Expect = 5e-11
Identities = 137/575 (23%), Positives = 199/575 (34%), Gaps = 103/575 (17%)
Query: 254 CRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
C CQ G +C + C S + ++FSC+ C T + +++E
Sbjct: 131 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK---CLTGFTGQKCETDVNE-- 185
Query: 311 LSLDINGRYEGGGKCLN--------CQHNTEGINCNK----CRPTYYRPYGKRWDELDVC 358
DI G + GG CLN C G C+ C P+ G D
Sbjct: 186 --CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG---TEG 415
C C P F CE C P + + C G Y NC+ C G TE
Sbjct: 244 FECNCLPGFEGSTCERNIDDC---PNHRCQNGGVCVDGVNTY-NCR-CPPQWTGQFCTED 298
Query: 416 -EHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECK----NCECNTVGSVSYVCDKL 466
+ C C C G C +C +G+ +C +C + S D++
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGC-VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 467 TG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
C C +G C+ A N P K CDT + ++GQ C C G+
Sbjct: 358 ASFSCMCPEGKAGLLCHLDDACISN-PCHKGALCDT--------NPLNGQYICTCPQGYK 408
Query: 524 GPRC----DQCL---------SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSAD 563
G C D+C +G + G +C+ C D S C D
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD 623
CL GG C C PG+ + C +++ + C +NG C K N +C
Sbjct: 469 --ATCLDKIGGFTC-LCMPGF----KGVHCELEINECQSNPCVNNGQCVDKVN--RFQC- 518
Query: 624 TCREQFYNYPAC----EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
C F P C ++C+ P + A C P G CQC G +C +
Sbjct: 519 LCPPGFTG-PVCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEE----- 569
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL-DGFYRLQTN 738
N+ +P C C G + CN +C + E CL DG +
Sbjct: 570 -NIDNCDPDPCHHGQCQ-DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDG----RCI 623
Query: 739 DVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
D+ +C+C G S NC+ C + + G
Sbjct: 624 DLVNGYQCNCQPGTS-GVNCEINFDDCASNPCIHG 657
Score = 67.7 bits (158), Expect = 7e-10
Identities = 99/380 (26%), Positives = 134/380 (35%), Gaps = 77/380 (20%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCV------PCQC-NGHSD-QCDVNTGICLNC 1784
C CP Y G +C+ R P G CV C C +G + CDV C +
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DI 1107
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNC 1843
A + G E H + + C CP+ Y + D + N C
Sbjct: 1108 AASRRGVLVEHLCQ--HSGVCINA-GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYC--KPC----NCSGNIN----PQDPGS--- 1890
GG RCE C GY G+ + ++ D C +PC C +N PG+
Sbjct: 1165 SDFIGGYRCE-CVPGYQGVNCEYEV---DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL 1220
Query: 1891 -CDSINGDCLK---------CVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMA 1938
C+ DC + C++ G +C C PGF G+ C + C G
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCR-CLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 1939 DCDSTTG--TCVCRPGVIGEKCDR---CAPDHWGLNTGLGCTP--------CNCGIASES 1985
DC T CVCR G C+ P LN G C C
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAG---FWNYTKD---GCDHCNCNTGYSVGFMCNAT 2039
+C GQ +C K G+QC A+G F +D GC C G S C+
Sbjct: 1340 ARCQSSCGQVKCRK---GEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGS----CHPQ 1392
Query: 2040 GQ-----CECLPGVIGEKCD 2054
Q C+C P G +C+
Sbjct: 1393 RQPPYYSCQCAPPFSGSRCE 1412
Score = 66.1 bits (154), Expect = 2e-09
Identities = 137/570 (24%), Positives = 193/570 (33%), Gaps = 96/570 (16%)
Query: 258 HNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC----NCHN--HTTECTYDPEIDEKRL 311
HNT G +C GF ++ D PC +C + +T C P +
Sbjct: 889 HNTQGSYMCECPPGFSGMD--CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Query: 312 SLDINGRY----EGGGKCLN--------CQHNTEGINC----NKCRPTYYRPYGKRWDEL 355
D+N + GG C + CQ +G++C N+C + G D +
Sbjct: 947 QTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI 1006
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEG 415
+ C C F+ C E C P +C G Y C+C L G G
Sbjct: 1007 NSFS-CLCPVGFTGSFCLHEINECSSHPCLNE---GTCVDGLGTYR----CSCPL-GYTG 1057
Query: 416 EHCTPTDGLC---PCKYN--YAGKSCE---ICEDGYYSPECK--NCECNTVGSVSYVCDK 465
++C LC PCK K E +C G+ C N C+ S V
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV- 1116
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC----ICKAG 521
+ C+ +SG N AG +Y C P S E + + S C C
Sbjct: 1117 ---EHLCQ--HSGVCIN---AGNTHYCQC-PLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNFGGAQCDQ 579
GG RC+ C+ GY Q + E + C P G T KC+C G C++
Sbjct: 1168 IGGYRCE-CVPGY--QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 1224
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDN--GL-CHCKSNFDGAKCDTCREQFYNYPACE 636
+ P CL+ G C D G C C F G +C+ + + P
Sbjct: 1225 NIDDCARGPHCLN---------GGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 637 ECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
E + D C + LC C+ GR C + + N C +
Sbjct: 1276 EGSLD----------CIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
Query: 697 LAGTL-----NSLGA-CNTKSGQCVCKQHVGERQCDQCLDG---FYRLQTNDVFGCTECD 747
G + GA C + GQ C++ GE QC G F + GC
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVKCRK--GE-QCVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 748 CDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C GGS C C G RC+
Sbjct: 1383 CQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
Score = 64.9 bits (151), Expect = 5e-09
Identities = 115/482 (23%), Positives = 161/482 (33%), Gaps = 65/482 (13%)
Query: 325 CLNCQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
CLN +G+ +C P Y GK L C P + G C ++ +C
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYT--GKNCQTL--VNLCSRSPCKNKGTCVQKKAESQC-- 1087
Query: 384 EFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P S A Y D PN + G EH G+C N C + G
Sbjct: 1088 -LCP---SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Query: 443 YYSPE-CKNCECNTVGSVSYVCDKLTG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCD 500
Y E C N + D + G C C Y G C Y C+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE------YEVDECQNQPCQ 1197
Query: 501 TSGTEPSICDDVSG--QCICKAGFGGPRCDQ----------CLSGYYM--QVLGRERQCV 546
GT C D+ +C C G G C++ CL+G ++ G +C+
Sbjct: 1198 NGGT----CIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCL 1253
Query: 547 P------CNCDPTGSTSTSCSADGKCNC--LTNFGGAQCDQCSPGYY--KYPD-CLSCNC 595
P C D S CS++G +C LTN C G + + D C C
Sbjct: 1254 PGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPC 1313
Query: 596 DVSGS--IGSTCDDNGLCHCKSNFDGAKC-DTCRE-QFYNYPACEECNCDPRGVTASFAG 651
G+ + S D +C C F GA+C +C + + C PR S
Sbjct: 1314 LNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 652 CGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNT- 709
C S A CQ G C+ +P Y++ Q PF +C A C +
Sbjct: 1374 CESGCASSPCQ-----HGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 710 ----KSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
K+ VC + C Q G L + + I+N CD+
Sbjct: 1429 YCADKARDGVCDEACNSHAC-QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV 1487
Query: 766 HC 767
C
Sbjct: 1488 EC 1489
Score = 64.5 bits (150), Expect = 7e-09
Identities = 112/468 (23%), Positives = 162/468 (34%), Gaps = 84/468 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSS--------CAYGY------FDYPNCKPC 406
C C P F +CE E C+ P C C G+ D +C
Sbjct: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 407 TCNLNGTEG-EHCTPTDGLCPCKYNYAGKSCE----ICE-DGYYSPECKN------CECN 454
C LNG + +H P C C + G CE C+ D + +C++ C CN
Sbjct: 540 PC-LNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN 596
Query: 455 TVGSVSYVCDKLTGDC---------TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE 505
G + +C +C C +G CN CQ G C+ N D +
Sbjct: 597 P-GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN-CQPGTSGV-NCE-INFDDCASN 652
Query: 506 P---SICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTG 554
P IC D + C+C GF G RC+ + + C+ C C P G
Sbjct: 653 PCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCIC-PEG 711
Query: 555 STSTSC-SADGKC--------NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC 605
SC S +C NC G +C C G+ ++C D + + + C
Sbjct: 712 PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC-LCDAGWVG----INCEVDKNECLSNPC 766
Query: 606 DDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQ 662
+ G C N G +C TC++ F Y +EC +P + C +G C
Sbjct: 767 QNGGTCDNLVN--GYRC-TCKKGFKGYNCQVNIDECASNP---CLNQGTCFDDISGYTCH 820
Query: 663 CKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG----ACNTKSGQCVCK 717
C G+ C P N E E N L + G C +C+ K
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 718 QHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
+ C G Y + F +C+ DI + N C + G C
Sbjct: 881 PCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPC-QNGGSC 926
Score = 62.9 bits (146), Expect = 2e-08
Identities = 96/400 (24%), Positives = 132/400 (33%), Gaps = 78/400 (19%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
P C GY N C NGT G C C + G+ C+ +
Sbjct: 22 PAHALQCRDGYEPCVNEGMCVTYHNGT---------GYCKCPEGFLGEYCQ------HRD 66
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC----NCDTS 502
C+ C G+ V + G TC+ SG T CQ Y T PC C
Sbjct: 67 PCEKNRCQNGGTC--VAQAMLGKATCRCA-SGFTGEDCQ-----YSTSHPCFVSRPCLNG 118
Query: 503 GTEPSICDDVSGQCICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
GT + D +C C+ GF G C D CLS PC GST T+
Sbjct: 119 GTCHMLSRDTY-ECTCQVGFTGKECQWTDACLSH-------------PC---ANGSTCTT 161
Query: 560 CSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC---DDNGLCHCKSN 616
+ C CLT F G +C+ D C+ G TC + C C
Sbjct: 162 VANQFSCKCLTGFTGQKCE---------TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 617 FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCK 676
F G CD+ P C G +F C +P E C+ + + C+
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTG-DFTFE-CNCLPGFEGSTCERNIDDCPNHRCQ 270
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ 736
+ N + C +C G C +C+ Q + C +G
Sbjct: 271 NGGVCVDGVNTYNC-RCPPQWTGQF-----CTEDVDECLL-------QPNACQNGGTCAN 317
Query: 737 TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
N +GC C + G ++C + C S G C
Sbjct: 318 RNGGYGCV-C---VNGWSGDDCSENIDDCAFASCTPGSTC 353
Score = 62.1 bits (144), Expect = 4e-08
Identities = 90/342 (26%), Positives = 125/342 (36%), Gaps = 64/342 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC G +C+ G+ GF C + D+C N CLN C D+ G
Sbjct: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGF-KGYNCQVNIDECASNP--CLNQGTCFDDISG 816
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C C+ Y G ++C P P P N A+ C S N +C C PG+ G
Sbjct: 817 YTCH-CVLPYTG-------KNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQG 867
Query: 1850 ARC----EYCAAG---YYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--- 1899
RC + C + +G+ +T G Y C C + D C+ DCL
Sbjct: 868 QRCTIDIDECISKPCMNHGLCHNTQ---GSYM--CECPPGFSGMD---CEEDIDDCLANP 919
Query: 1900 -----KCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGTCVCRPG 1952
C++ +C LC PGF GD + C + C G + TC C+ G
Sbjct: 920 CQNGGSCMDGVNTFSC-LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAA 2011
G C+ +N CT +C + T D N C C G TG C
Sbjct: 979 FDGVHCEN------NINE---CTESSC--FNGGTCVDGINSFSCLCPVGFTGSFC----- 1022
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+ + H N G V + T +C C G G+ C
Sbjct: 1023 --LHEINECSSHPCLNEGTCVDGL--GTYRCSCPLGYTGKNC 1060
Score = 61.7 bits (143), Expect = 5e-08
Identities = 99/429 (23%), Positives = 150/429 (34%), Gaps = 74/429 (17%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYAGKSC 436
C C ++ DC+ D C N G+ C TDG C C YAG C
Sbjct: 401 CTCPQGYKGADCTE------DVDECAMANSNPCEHAGK-CVNTDGAFHCECLKGYAGPRC 453
Query: 437 EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
E+ + +S C+N D TC K G TC C G+
Sbjct: 454 EMDINECHSDPCQN------------------DATCLDKIGGFTC-LCMPGFKGV----H 490
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C + + + + C + +GQC+ K C +G Q+ + PC G+
Sbjct: 491 CELEINECQSNPCVN-NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC---LNGAK 546
Query: 557 STSCSADGKCNCLTNFGGAQC----DQCSPGYYKYPDC------LSCNCDVSGSIGSTCD 606
+C C T F G C D C P + C +C C+ G +G+ C
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN-PGYMGAICS 605
Query: 607 DN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTA--SFAGCGSVPAGELC 661
D C+ + +C + +CNC P GV +F C S P
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGY-------QCNCQPGTSGVNCEINFDDCASNPCIHGI 658
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG-QCVCKQHV 720
C D + C C P + Q N ++C N N +G +C+C +
Sbjct: 659 -CMDGINRYSC-VCSPGFTG-QRCN-IDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
Query: 721 GERQC----DQCLDG--FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
C ++CL + T + G +C CD G + NC+ +C + G
Sbjct: 713 HHPSCYSQVNECLSNPCIHGNCTGGLSG-YKCLCD-AGWVGINCEVDKNECLSNPCQNGG 770
Query: 775 RCDQPIRAH 783
CD + +
Sbjct: 771 TCDNLVNGY 779
Score = 61.3 bits (142), Expect = 6e-08
Identities = 86/344 (25%), Positives = 114/344 (33%), Gaps = 42/344 (12%)
Query: 1733 VEECQC-PRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
+ ECQ P G ++ P GF P C D C CLN C D+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPV-CQIDIDDCSSTP--CLNGAKCIDHP 551
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C +G+ G +C P P ++ + +C C PGY
Sbjct: 552 NGYECQ-CATGFTGVLCEENIDNC------DPDPCHHGQCQDGIDS----YTCICNPGYM 600
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK--PCNC----SG---NINPQDPGSCDSINGDCL 1899
GA C Y P D D CNC SG IN D S I+G C+
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TCVCRPGVIGE 1956
+N + C +C+PGF G I C + C + G + G C+C G
Sbjct: 661 DGINRYS---C-VCSPGFTGQRCNIDIDECASNPCRK-GATCINGVNGFRCICPEGPHHP 715
Query: 1957 KC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
C + C + H GL C C C+ D +C G CD
Sbjct: 716 SCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL 775
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G+ K G NC Q C + G C
Sbjct: 776 VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
Score = 60.1 bits (139), Expect = 1e-07
Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 46/304 (15%)
Query: 1784 CADNTI-GDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C N + G + C GY G D T D CA P + A C ++ +G+ C
Sbjct: 390 CDTNPLNGQYICTCPQGYKGADCT----EDVDECAMANSNPCEH-AGKC-VNTDGAF-HC 442
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGD-------YCKP----CNCSGNINPQDPGS 1890
C GY G RCE + P D D C P +C IN
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TC 1947
C + NG C+ VN C LC PGF G I +C++ C G D G C
Sbjct: 503 CVN-NGQCVDKVNRFQ---C-LCPPGFTGPVCQIDIDDCSSTPCLN-GAKCIDHPNGYEC 556
Query: 1948 VCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C G G C D C PD H G+ C C C D +C +
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYS--------VGFMCNATGQ--CECLPGVIG 2050
+ +C G+ + G NC + G + + C C PG G
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 2051 EKCD 2054
++C+
Sbjct: 677 QRCN 680
Score = 57.2 bits (132), Expect = 1e-06
Identities = 87/351 (24%), Positives = 120/351 (34%), Gaps = 57/351 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC C + G C Q + P C + C TG + + + C+
Sbjct: 130 ECTCQVGFTGKEC-QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE-CD 187
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPS---NNFALSCDLSE--NGSL--------ISC 1841
HG + P C CP + ++ + C S NG C
Sbjct: 188 IPGHCQHGGTCLNLPGSYQ-CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 1842 NCQPGYGGARCE---------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
NC PG+ G+ CE C G G+ D ++T + P +G +D C
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNG--GVCVD-GVNTYNCRCPPQWTGQFCTEDVDECL 303
Query: 1893 SINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C C N G C +C G+ GD +C+ I D+ A C + TC+
Sbjct: 304 LQPNACQNGGTCANRNGGYGC-VCVNGWSGD-----DCSENI-DDCAFASC-TPGSTCID 355
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRCAKGVTGKQ 2005
R V C C GL L C + CD + NGQ C C +G G
Sbjct: 356 R--VASFSC-MCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGAD 411
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATG--QCECLPGVIGEKCD 2054
C + D C N N G N G CECL G G +C+
Sbjct: 412 CTE--------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
Score = 56.8 bits (131), Expect = 1e-06
Identities = 92/387 (23%), Positives = 131/387 (33%), Gaps = 62/387 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + Y G CE + C C + D G C G HCE
Sbjct: 442 CECLKGYAGPRCE--------MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
Query: 1796 CMSGYHGDATVGTPR-----DCLICACPMPYPSNNFALSC-DLSENGSLISCNCQPGYGG 1849
++ + V + + C CP + + D S L C G
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG 553
Query: 1850 ARCEYCAAGYYGI--PEDTDLHTGDYCKPCNCSGNINPQ----DPGSCDSINGD------ 1897
C+ CA G+ G+ E+ D D C C I+ +PG +I D
Sbjct: 554 YECQ-CATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 1898 ---CL---KCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
CL +C++ G CN C PG G I +C + C G+ +CVC
Sbjct: 613 SSPCLNDGRCIDLVNGYQCN-CQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVC 670
Query: 1950 RPGVIGEKC----DRCA--PDHWGLN--TGLGCTPCNCGIASESTQCDDDNGQC------ 1995
PG G++C D CA P G G+ C C C +C
Sbjct: 671 SPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 1996 --RCAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVI 2049
C G++G +C C AG+ K+ C C G + + N +C C G
Sbjct: 731 HGNCTGGLSGYKC-LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY-RCTCKKGFK 788
Query: 2050 GEKCDRCPERWVLIPQEGCLECDSCTD 2076
G C + P CL +C D
Sbjct: 789 GYNCQVNIDECASNP---CLNQGTCFD 812
Score = 52.4 bits (120), Expect = 3e-05
Identities = 93/374 (24%), Positives = 125/374 (33%), Gaps = 67/374 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G C ++ + PC +G D+ G NC T G +CE
Sbjct: 593 CICNPGYMGAICSD------QIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVNCEI 644
Query: 1796 ----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C S HG G R +C+ N + + + N C G G
Sbjct: 645 NFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID-ECASNPCRKGATCINGVNG 703
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPC---NCSGNINPQ----DPG----SCDSINGDC 1898
RC C G + P PC NC+G ++ D G +C+ +C
Sbjct: 704 FRC-ICPEGPHH-PSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
Query: 1899 LK--------CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
L C N G C C GF G NC I DE C GTC
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCT-CKKGFKG-----YNCQVNI-DECASNPC-LNQGTCF-- 811
Query: 1951 PGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----DNGQCRCAKGVTGKQC 2006
+ G C C + G N PC+ + C + ++ C CA G G++C
Sbjct: 812 DDISGYTC-HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Query: 2007 DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCDRCPERWVLIP 2064
T D D C + G N G CEC PG G C+ + + P
Sbjct: 871 ----------TID-IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 2065 QEGCLECDSCTDAL 2078
C SC D +
Sbjct: 920 ---CQNGGSCMDGV 930
Score = 48.0 bits (109), Expect = 6e-04
Identities = 73/295 (24%), Positives = 108/295 (36%), Gaps = 67/295 (22%)
Query: 1766 QCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNN 1825
QC + C VN G+C+ + T +C+ C G+ G+ C P N
Sbjct: 27 QCRDGYEPC-VNEGMCVTYHNGT--GYCK-CPEGFLGE----------YCQHRDPCEKNR 72
Query: 1826 FALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC---KPCNCSGN 1882
C +NG +C Q G A C CA+G+ G ED T C +PC
Sbjct: 73 ----C---QNGG--TCVAQAMLGKATCR-CASGFTG--EDCQYSTSHPCFVSRPC----- 115
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTACICDEFGMADCD 1941
+ G+C ++ D +C C GF G + ++ C + C
Sbjct: 116 ---LNGGTCHMLSRDTYECT----------CQVGFTGKECQWTDACLSHPCANGSTCTTV 162
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKG 2000
+ +C C G G+KC+ + C P +C QC+C +G
Sbjct: 163 ANQFSCKCLTGFTGQKCETDVNE---------CDIPGHCQHGGTCLNLPGSY-QCQCPQG 212
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
TG+ CD Y C C G + + T +C CLPG G C+R
Sbjct: 213 FTGQYCDSL------YVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 27/149 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNC--RPCHCPSTAICDDNGM-CICPKNVEGENC-DRC 1414
C C P G+ C+ C PC +T I NG CICP+ +C +
Sbjct: 668 CVCSPGFTGQRCNI------DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Query: 1415 KPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
N + C C C+ G VG + CE D +C G CD+ V G
Sbjct: 722 NECLSNPCIHGNCTGGLSGYKCLCDA-GWVG--INCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Y+CTC + Y+ C N +C
Sbjct: 779 -------YRCTCKKGFKGYN-CQVNIDEC 799
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/181 (25%), Positives = 62/181 (34%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCR--PCHCP 1389
C C +G T C +C P G TCS C GY G NC C
Sbjct: 1135 CQCP-LGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGV-NCEYEVDECQ 1192
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
+ C + G CI V C C P T + DDC P + G Q
Sbjct: 1193 NQP-CQNGGTCI--DLVNHFKCS-CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C C G C+ + +C C+ G+ + N C C++ G+ C+
Sbjct: 1249 SCRCLPGFAGERCEGDI------NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Query: 1510 T 1510
T
Sbjct: 1303 T 1303
Score = 44.0 bits (99), Expect = 0.010
Identities = 47/191 (24%), Positives = 69/191 (36%), Gaps = 16/191 (8%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPC--HCPSTAICDDNGMCICPKNVEGENCDRCKP 1416
C PN TC C G+ G C C S C ++G+C N +G C P
Sbjct: 848 CKESPNFESYTC-LCAPGWQG-QRCTIDIDECISKP-CMNHGLC---HNTQGSYMCECPP 901
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
D + DDC NP G+ + ++ C C G C + + P
Sbjct: 902 GFSGMDCEEDIDDCLANPCQNGGSCMD-GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
Query: 1477 QCTCNRHGTTYDV-CDQNTAQCYCKTNVR---GQAC---DTCKEEYFNLQDDNPDGCTKC 1529
TC+ + +Y C +C+ N+ +C TC + + P G T
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS 1020
Query: 1530 FCFGKTTRCSS 1540
FC + CSS
Sbjct: 1021 FCLHEINECSS 1031
Score = 41.5 bits (93), Expect = 0.056
Identities = 51/184 (27%), Positives = 66/184 (35%), Gaps = 26/184 (14%)
Query: 1336 GARPCLC--DFMG-STELECNTFGGQCPCKPN-----VIGRTCSACRTGYYGFPNCRPC- 1386
G CLC F G ELE N PC N + R C G+ G P C+
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQCVDKVNRFQCLCPPGFTG-PVCQIDI 533
Query: 1387 -HCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C ST C + CI N G C +T + D+C+ +P Q Q
Sbjct: 534 DDCSSTP-CLNGAKCIDHPN--GYECQCATGFT-GVLCEENIDNCDPDPCH--HGQCQDG 587
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRG 1505
DS C C G +C + +CY C G D+ N QC C+ G
Sbjct: 588 IDSYTCICNPGYMGAICSDQI------DECYSSPCLNDGRCIDLV--NGYQCNCQPGTSG 639
Query: 1506 QACD 1509
C+
Sbjct: 640 VNCE 643
Score = 40.3 bits (90), Expect = 0.13
Identities = 58/228 (25%), Positives = 75/228 (32%), Gaps = 28/228 (12%)
Query: 1757 LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICA 1816
+P GF C +C + G + C G+ C SG +PRDC
Sbjct: 1325 MPDGFICRCPPGFSGARCQSSCGQ-VKCRK---GEQCVHTASGPR--CFCPSPRDCESGC 1378
Query: 1817 CPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
P SC SC C P + G+RCE A P T L YC
Sbjct: 1379 ASSPCQHGG---SCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCL--SQYCAD 1432
Query: 1877 CNCSGNINPQ-DPGSCDSINGDC-LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICD 1933
G + + +C GDC L N A + L C N C+ D
Sbjct: 1433 KARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFD 1492
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN-TGLGCTPCNCG 1980
F +C + TC K D+ DH+ N GC CG
Sbjct: 1493 NF---ECQGNSKTC---------KYDKYCADHFKDNHCDQGCNSEECG 1528
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/212 (21%), Positives = 73/212 (34%), Gaps = 14/212 (6%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEG 415
C+C P FS C+ G+ +CR Q +S + P C C G+
Sbjct: 1331 CRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
Query: 416 EHCTPTDGLCPCKYNYAGKSCEICEDGYYSP--ECKNCECNTVGSVSYVCDKLTGDCTCK 473
P C C ++G CE+ +P C + C VCD+ C
Sbjct: 1391 PQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKAR-DGVCDEACNSHAC- 1448
Query: 474 SKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
++ G C+ + + N + PC + +C+ V +C+ C
Sbjct: 1449 -QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV--ECLFDNFECQGNSKTCKY 1505
Query: 533 GYYMQVLGRERQC-VPCNCDPTGSTSTSCSAD 563
Y ++ C CN + G C+AD
Sbjct: 1506 DKYCADHFKDNHCDQGCNSEECGWDGLDCAAD 1537
Score = 35.5 bits (78), Expect = 3.6
Identities = 51/216 (23%), Positives = 74/216 (34%), Gaps = 30/216 (13%)
Query: 1301 REFIEQCASYNYYIS-PNETGLCREAMFSITSEYNSGARPC---LCDFMGSTELECNTFG 1356
R+ E C + ++ N TG C+ EY PC C G+ +
Sbjct: 29 RDGYEPCVNEGMCVTYHNGTGYCK-CPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 87
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA--ICDDNGMCICPKNVEGENCDRC 1414
C C G C T + F + RPC T + D C C G+ C
Sbjct: 88 ATCRCASGFTGEDCQYS-TSHPCFVS-RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-- 143
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD 1474
+T + + C N + V NQ C+ +G + CD +PGH
Sbjct: 144 --WT-DACLSHPC--ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD--IPGH----- 191
Query: 1475 CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C GT ++ + QC C GQ CD+
Sbjct: 192 -----CQHGGTCLNL--PGSYQCQCPQGFTGQYCDS 220
Score = 35.1 bits (77), Expect = 4.8
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 21/226 (9%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRPCHCPST 1391
CLC G T +C T +C +P G TCS C+ G+ G + +
Sbjct: 935 CLC-LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
Query: 1392 AICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG-- 1449
+ C + G C+ + +C +T +F + ++C+ +P N+ C G
Sbjct: 994 SSCFNGGTCV--DGINSFSCLCPVGFTGSFCLHE-INECSSHP---CLNEGTCVDGLGTY 1047
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTC-NRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C+C G+ C V P + TC + + +C A YC +V +C
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC--DVPNVSC 1105
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSY-YTWAAIDEMVD 1553
D L + C G T C YT + +E +D
Sbjct: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 78.2 bits (184), Expect = 5e-13
Identities = 114/445 (25%), Positives = 158/445 (35%), Gaps = 67/445 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C P FS +CEE+ C P C D N C C L G G+ C
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSC-------MDGVNTFSCLC-LPGFTGDKCQT 948
Query: 421 TDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
C PCK G +C + Y C+C G C+ +CT S ++
Sbjct: 949 DMNECLSEPCK---NGGTCSDYVNSY------TCKCQ-AGFDGVHCENNINECTESSCFN 998
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI----CKAGFGGPRCDQCLSG 533
G TC G ++ P S I + S C+ C G G RC C G
Sbjct: 999 GGTCVD---GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLG 1054
Query: 534 YY-MQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Y C C G T A+ +C C + + GA CD P +
Sbjct: 1055 YTGKNCQTLVNLCSRSPCKNKG-TCVQKKAESQCLCPSGWAGAYCD--------VP---N 1102
Query: 593 CNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGV 645
+CD++ S + C +G+C N +C Y +EC +P G
Sbjct: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGA 1162
Query: 646 TAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
T S F G C VP + C+ V C+ + N F C C G L
Sbjct: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC-SCPPGTRGLL 1221
Query: 702 --NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSI 754
++ C + C+ C +G C +CL GF + D+ C C GS+
Sbjct: 1222 CEENIDDC-ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 755 DNNCDKTTGQ--CHCHSRVEGRRCD 777
D C + T C C S GR C+
Sbjct: 1280 D--CIQLTNDYLCVCRSAFTGRHCE 1302
Score = 75.8 bits (178), Expect = 3e-12
Identities = 133/575 (23%), Positives = 192/575 (33%), Gaps = 78/575 (13%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C+C G C + + Q D C C+ +IDE S
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 314 DIN-GR---YEGGGKCLNCQHNTEGINCN-KCRPTYYRP--YGKRWDELDVCQPCQCDPH 366
+N GR G +C NCQ T G+NC P +G D ++ C C P
Sbjct: 616 CLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS-CVCSPG 673
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----DYPNCKPCTCNLNGTEGEHCTP-- 420
F+ C + C P + C + G+ + P+ C +N C
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Query: 421 -TDGL----CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
T GL C C + G +CE+ ++ EC + C G+ CD L CTCK
Sbjct: 734 CTGGLSGYKCLCDAGWVGINCEVDKN-----ECLSNPCQNGGT----CDNLVNGYRCTCK 784
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLS 532
+ G C N C C GT DD+SG C C + G C L+
Sbjct: 785 KGFKGYNCQ------VNIDECASNPCLNQGT---CFDDISGYTCHCVLPYTGKNCQTVLA 835
Query: 533 GYYMQVLGRERQC--------VPCNCDPTGSTSTSCSAD-GKC---NCLT-----NFGGA 575
C C C P G C+ D +C C+ N G+
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAP-GWQGQRCTIDIDECISKPCMNHGLCHNTQGS 894
Query: 576 QCDQCSPGYY------KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
+C PG+ DCL+ C GS + C C F G KC T +
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS-CLCLPGFTGDKCQTDMNEC 953
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ P C V + C + G C++ + + C + N F
Sbjct: 954 LSEPCKNGGTCSDY-VNSYTCKCQAGFDG--VHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 690 CEQCNCNLAGT--LNSLGACNTKS--GQCVCKQHVGERQCDQCLDGFYRLQTNDVFG-CT 744
C C G+ L+ + C++ + C +G +C C G+ + C+
Sbjct: 1011 C-LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCS 1068
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C G+ K QC C S G CD P
Sbjct: 1069 RSPCKNKGTCVQK--KAESQCLCPSGWAGAYCDVP 1101
Score = 71.7 bits (168), Expect = 5e-11
Identities = 137/575 (23%), Positives = 199/575 (34%), Gaps = 103/575 (17%)
Query: 254 CRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
C CQ G +C + C S + ++FSC+ C T + +++E
Sbjct: 131 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK---CLTGFTGQKCETDVNE-- 185
Query: 311 LSLDINGRYEGGGKCLN--------CQHNTEGINCNK----CRPTYYRPYGKRWDELDVC 358
DI G + GG CLN C G C+ C P+ G D
Sbjct: 186 --CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG---TEG 415
C C P F CE C P + + C G Y NC+ C G TE
Sbjct: 244 FECNCLPGFEGSTCERNIDDC---PNHRCQNGGVCVDGVNTY-NCR-CPPQWTGQFCTED 298
Query: 416 -EHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECK----NCECNTVGSVSYVCDKL 466
+ C C C G C +C +G+ +C +C + S D++
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGC-VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 467 TG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
C C +G C+ A N P K CDT + ++GQ C C G+
Sbjct: 358 ASFSCMCPEGKAGLLCHLDDACISN-PCHKGALCDT--------NPLNGQYICTCPQGYK 408
Query: 524 GPRC----DQCL---------SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSAD 563
G C D+C +G + G +C+ C D S C D
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD 623
CL GG C C PG+ + C +++ + C +NG C K N +C
Sbjct: 469 --ATCLDKIGGFTC-LCMPGF----KGVHCELEINECQSNPCVNNGQCVDKVN--RFQC- 518
Query: 624 TCREQFYNYPAC----EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
C F P C ++C+ P + A C P G CQC G +C +
Sbjct: 519 LCPPGFTG-PVCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEE----- 569
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL-DGFYRLQTN 738
N+ +P C C G + CN +C + E CL DG +
Sbjct: 570 -NIDNCDPDPCHHGQCQ-DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDG----RCI 623
Query: 739 DVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
D+ +C+C G S NC+ C + + G
Sbjct: 624 DLVNGYQCNCQPGTS-GVNCEINFDDCASNPCIHG 657
Score = 67.7 bits (158), Expect = 7e-10
Identities = 99/380 (26%), Positives = 134/380 (35%), Gaps = 77/380 (20%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCV------PCQC-NGHSD-QCDVNTGICLNC 1784
C CP Y G +C+ R P G CV C C +G + CDV C +
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DI 1107
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNC 1843
A + G E H + + C CP+ Y + D + N C
Sbjct: 1108 AASRRGVLVEHLCQ--HSGVCINA-GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYC--KPC----NCSGNIN----PQDPGS--- 1890
GG RCE C GY G+ + ++ D C +PC C +N PG+
Sbjct: 1165 SDFIGGYRCE-CVPGYQGVNCEYEV---DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL 1220
Query: 1891 -CDSINGDCLK---------CVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMA 1938
C+ DC + C++ G +C C PGF G+ C + C G
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCR-CLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 1939 DCDSTTG--TCVCRPGVIGEKCDR---CAPDHWGLNTGLGCTP--------CNCGIASES 1985
DC T CVCR G C+ P LN G C C
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAG---FWNYTKD---GCDHCNCNTGYSVGFMCNAT 2039
+C GQ +C K G+QC A+G F +D GC C G S C+
Sbjct: 1340 ARCQSSCGQVKCRK---GEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGS----CHPQ 1392
Query: 2040 GQ-----CECLPGVIGEKCD 2054
Q C+C P G +C+
Sbjct: 1393 RQPPYYSCQCAPPFSGSRCE 1412
Score = 66.1 bits (154), Expect = 2e-09
Identities = 137/570 (24%), Positives = 193/570 (33%), Gaps = 96/570 (16%)
Query: 258 HNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC----NCHN--HTTECTYDPEIDEKRL 311
HNT G +C GF ++ D PC +C + +T C P +
Sbjct: 889 HNTQGSYMCECPPGFSGMD--CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Query: 312 SLDINGRY----EGGGKCLN--------CQHNTEGINC----NKCRPTYYRPYGKRWDEL 355
D+N + GG C + CQ +G++C N+C + G D +
Sbjct: 947 QTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI 1006
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEG 415
+ C C F+ C E C P +C G Y C+C L G G
Sbjct: 1007 NSFS-CLCPVGFTGSFCLHEINECSSHPCLNE---GTCVDGLGTYR----CSCPL-GYTG 1057
Query: 416 EHCTPTDGLC---PCKYN--YAGKSCE---ICEDGYYSPECK--NCECNTVGSVSYVCDK 465
++C LC PCK K E +C G+ C N C+ S V
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV- 1116
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC----ICKAG 521
+ C+ +SG N AG +Y C P S E + + S C C
Sbjct: 1117 ---EHLCQ--HSGVCIN---AGNTHYCQC-PLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNFGGAQCDQ 579
GG RC+ C+ GY Q + E + C P G T KC+C G C++
Sbjct: 1168 IGGYRCE-CVPGY--QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 1224
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDN--GL-CHCKSNFDGAKCDTCREQFYNYPACE 636
+ P CL+ G C D G C C F G +C+ + + P
Sbjct: 1225 NIDDCARGPHCLN---------GGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 637 ECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
E + D C + LC C+ GR C + + N C +
Sbjct: 1276 EGSLD----------CIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
Query: 697 LAGTL-----NSLGA-CNTKSGQCVCKQHVGERQCDQCLDG---FYRLQTNDVFGCTECD 747
G + GA C + GQ C++ GE QC G F + GC
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVKCRK--GE-QCVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 748 CDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C GGS C C G RC+
Sbjct: 1383 CQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
Score = 64.9 bits (151), Expect = 5e-09
Identities = 115/482 (23%), Positives = 161/482 (33%), Gaps = 65/482 (13%)
Query: 325 CLNCQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
CLN +G+ +C P Y GK L C P + G C ++ +C
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYT--GKNCQTL--VNLCSRSPCKNKGTCVQKKAESQC-- 1087
Query: 384 EFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P S A Y D PN + G EH G+C N C + G
Sbjct: 1088 -LCP---SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Query: 443 YYSPE-CKNCECNTVGSVSYVCDKLTG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCD 500
Y E C N + D + G C C Y G C Y C+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE------YEVDECQNQPCQ 1197
Query: 501 TSGTEPSICDDVSG--QCICKAGFGGPRCDQ----------CLSGYYM--QVLGRERQCV 546
GT C D+ +C C G G C++ CL+G ++ G +C+
Sbjct: 1198 NGGT----CIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCL 1253
Query: 547 P------CNCDPTGSTSTSCSADGKCNC--LTNFGGAQCDQCSPGYY--KYPD-CLSCNC 595
P C D S CS++G +C LTN C G + + D C C
Sbjct: 1254 PGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPC 1313
Query: 596 DVSGS--IGSTCDDNGLCHCKSNFDGAKC-DTCRE-QFYNYPACEECNCDPRGVTASFAG 651
G+ + S D +C C F GA+C +C + + C PR S
Sbjct: 1314 LNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 652 CGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNT- 709
C S A CQ G C+ +P Y++ Q PF +C A C +
Sbjct: 1374 CESGCASSPCQ-----HGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 710 ----KSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
K+ VC + C Q G L + + I+N CD+
Sbjct: 1429 YCADKARDGVCDEACNSHAC-QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV 1487
Query: 766 HC 767
C
Sbjct: 1488 EC 1489
Score = 64.5 bits (150), Expect = 7e-09
Identities = 112/468 (23%), Positives = 162/468 (34%), Gaps = 84/468 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSS--------CAYGY------FDYPNCKPC 406
C C P F +CE E C+ P C C G+ D +C
Sbjct: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 407 TCNLNGTEG-EHCTPTDGLCPCKYNYAGKSCE----ICE-DGYYSPECKN------CECN 454
C LNG + +H P C C + G CE C+ D + +C++ C CN
Sbjct: 540 PC-LNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN 596
Query: 455 TVGSVSYVCDKLTGDC---------TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE 505
G + +C +C C +G CN CQ G C+ N D +
Sbjct: 597 P-GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN-CQPGTSGV-NCE-INFDDCASN 652
Query: 506 P---SICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTG 554
P IC D + C+C GF G RC+ + + C+ C C P G
Sbjct: 653 PCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCIC-PEG 711
Query: 555 STSTSC-SADGKC--------NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC 605
SC S +C NC G +C C G+ ++C D + + + C
Sbjct: 712 PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC-LCDAGWVG----INCEVDKNECLSNPC 766
Query: 606 DDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQ 662
+ G C N G +C TC++ F Y +EC +P + C +G C
Sbjct: 767 QNGGTCDNLVN--GYRC-TCKKGFKGYNCQVNIDECASNP---CLNQGTCFDDISGYTCH 820
Query: 663 CKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG----ACNTKSGQCVCK 717
C G+ C P N E E N L + G C +C+ K
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 718 QHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
+ C G Y + F +C+ DI + N C + G C
Sbjct: 881 PCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPC-QNGGSC 926
Score = 62.9 bits (146), Expect = 2e-08
Identities = 96/400 (24%), Positives = 132/400 (33%), Gaps = 78/400 (19%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
P C GY N C NGT G C C + G+ C+ +
Sbjct: 22 PAHALQCRDGYEPCVNEGMCVTYHNGT---------GYCKCPEGFLGEYCQ------HRD 66
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC----NCDTS 502
C+ C G+ V + G TC+ SG T CQ Y T PC C
Sbjct: 67 PCEKNRCQNGGTC--VAQAMLGKATCRCA-SGFTGEDCQ-----YSTSHPCFVSRPCLNG 118
Query: 503 GTEPSICDDVSGQCICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
GT + D +C C+ GF G C D CLS PC GST T+
Sbjct: 119 GTCHMLSRDTY-ECTCQVGFTGKECQWTDACLSH-------------PC---ANGSTCTT 161
Query: 560 CSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC---DDNGLCHCKSN 616
+ C CLT F G +C+ D C+ G TC + C C
Sbjct: 162 VANQFSCKCLTGFTGQKCE---------TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 617 FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCK 676
F G CD+ P C G +F C +P E C+ + + C+
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTG-DFTFE-CNCLPGFEGSTCERNIDDCPNHRCQ 270
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ 736
+ N + C +C G C +C+ Q + C +G
Sbjct: 271 NGGVCVDGVNTYNC-RCPPQWTGQF-----CTEDVDECLL-------QPNACQNGGTCAN 317
Query: 737 TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
N +GC C + G ++C + C S G C
Sbjct: 318 RNGGYGCV-C---VNGWSGDDCSENIDDCAFASCTPGSTC 353
Score = 62.1 bits (144), Expect = 4e-08
Identities = 90/342 (26%), Positives = 125/342 (36%), Gaps = 64/342 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC G +C+ G+ GF C + D+C N CLN C D+ G
Sbjct: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGF-KGYNCQVNIDECASNP--CLNQGTCFDDISG 816
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C C+ Y G ++C P P P N A+ C S N +C C PG+ G
Sbjct: 817 YTCH-CVLPYTG-------KNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQG 867
Query: 1850 ARC----EYCAAG---YYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--- 1899
RC + C + +G+ +T G Y C C + D C+ DCL
Sbjct: 868 QRCTIDIDECISKPCMNHGLCHNTQ---GSYM--CECPPGFSGMD---CEEDIDDCLANP 919
Query: 1900 -----KCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGTCVCRPG 1952
C++ +C LC PGF GD + C + C G + TC C+ G
Sbjct: 920 CQNGGSCMDGVNTFSC-LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAA 2011
G C+ +N CT +C + T D N C C G TG C
Sbjct: 979 FDGVHCEN------NINE---CTESSC--FNGGTCVDGINSFSCLCPVGFTGSFC----- 1022
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+ + H N G V + T +C C G G+ C
Sbjct: 1023 --LHEINECSSHPCLNEGTCVDGL--GTYRCSCPLGYTGKNC 1060
Score = 61.7 bits (143), Expect = 5e-08
Identities = 99/429 (23%), Positives = 150/429 (34%), Gaps = 74/429 (17%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYAGKSC 436
C C ++ DC+ D C N G+ C TDG C C YAG C
Sbjct: 401 CTCPQGYKGADCTE------DVDECAMANSNPCEHAGK-CVNTDGAFHCECLKGYAGPRC 453
Query: 437 EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
E+ + +S C+N D TC K G TC C G+
Sbjct: 454 EMDINECHSDPCQN------------------DATCLDKIGGFTC-LCMPGFKGV----H 490
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C + + + + C + +GQC+ K C +G Q+ + PC G+
Sbjct: 491 CELEINECQSNPCVN-NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC---LNGAK 546
Query: 557 STSCSADGKCNCLTNFGGAQC----DQCSPGYYKYPDC------LSCNCDVSGSIGSTCD 606
+C C T F G C D C P + C +C C+ G +G+ C
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN-PGYMGAICS 605
Query: 607 DN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTA--SFAGCGSVPAGELC 661
D C+ + +C + +CNC P GV +F C S P
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGY-------QCNCQPGTSGVNCEINFDDCASNPCIHGI 658
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG-QCVCKQHV 720
C D + C C P + Q N ++C N N +G +C+C +
Sbjct: 659 -CMDGINRYSC-VCSPGFTG-QRCN-IDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
Query: 721 GERQC----DQCLDG--FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
C ++CL + T + G +C CD G + NC+ +C + G
Sbjct: 713 HHPSCYSQVNECLSNPCIHGNCTGGLSG-YKCLCD-AGWVGINCEVDKNECLSNPCQNGG 770
Query: 775 RCDQPIRAH 783
CD + +
Sbjct: 771 TCDNLVNGY 779
Score = 61.3 bits (142), Expect = 6e-08
Identities = 86/344 (25%), Positives = 114/344 (33%), Gaps = 42/344 (12%)
Query: 1733 VEECQC-PRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
+ ECQ P G ++ P GF P C D C CLN C D+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPV-CQIDIDDCSSTP--CLNGAKCIDHP 551
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C +G+ G +C P P ++ + +C C PGY
Sbjct: 552 NGYECQ-CATGFTGVLCEENIDNC------DPDPCHHGQCQDGIDS----YTCICNPGYM 600
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK--PCNC----SG---NINPQDPGSCDSINGDCL 1899
GA C Y P D D CNC SG IN D S I+G C+
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TCVCRPGVIGE 1956
+N + C +C+PGF G I C + C + G + G C+C G
Sbjct: 661 DGINRYS---C-VCSPGFTGQRCNIDIDECASNPCRK-GATCINGVNGFRCICPEGPHHP 715
Query: 1957 KC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
C + C + H GL C C C+ D +C G CD
Sbjct: 716 SCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL 775
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G+ K G NC Q C + G C
Sbjct: 776 VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
Score = 60.1 bits (139), Expect = 1e-07
Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 46/304 (15%)
Query: 1784 CADNTI-GDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C N + G + C GY G D T D CA P + A C ++ +G+ C
Sbjct: 390 CDTNPLNGQYICTCPQGYKGADCT----EDVDECAMANSNPCEH-AGKC-VNTDGAF-HC 442
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGD-------YCKP----CNCSGNINPQDPGS 1890
C GY G RCE + P D D C P +C IN
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TC 1947
C + NG C+ VN C LC PGF G I +C++ C G D G C
Sbjct: 503 CVN-NGQCVDKVNRFQ---C-LCPPGFTGPVCQIDIDDCSSTPCLN-GAKCIDHPNGYEC 556
Query: 1948 VCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C G G C D C PD H G+ C C C D +C +
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYS--------VGFMCNATGQ--CECLPGVIG 2050
+ +C G+ + G NC + G + + C C PG G
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 2051 EKCD 2054
++C+
Sbjct: 677 QRCN 680
Score = 57.2 bits (132), Expect = 1e-06
Identities = 87/351 (24%), Positives = 120/351 (34%), Gaps = 57/351 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC C + G C Q + P C + C TG + + + C+
Sbjct: 130 ECTCQVGFTGKEC-QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE-CD 187
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPS---NNFALSCDLSE--NGSL--------ISC 1841
HG + P C CP + ++ + C S NG C
Sbjct: 188 IPGHCQHGGTCLNLPGSYQ-CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 1842 NCQPGYGGARCE---------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
NC PG+ G+ CE C G G+ D ++T + P +G +D C
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNG--GVCVD-GVNTYNCRCPPQWTGQFCTEDVDECL 303
Query: 1893 SINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C C N G C +C G+ GD +C+ I D+ A C + TC+
Sbjct: 304 LQPNACQNGGTCANRNGGYGC-VCVNGWSGD-----DCSENI-DDCAFASC-TPGSTCID 355
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRCAKGVTGKQ 2005
R V C C GL L C + CD + NGQ C C +G G
Sbjct: 356 R--VASFSC-MCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGAD 411
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATG--QCECLPGVIGEKCD 2054
C + D C N N G N G CECL G G +C+
Sbjct: 412 CTE--------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
Score = 56.8 bits (131), Expect = 1e-06
Identities = 92/387 (23%), Positives = 131/387 (33%), Gaps = 62/387 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + Y G CE + C C + D G C G HCE
Sbjct: 442 CECLKGYAGPRCE--------MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
Query: 1796 CMSGYHGDATVGTPR-----DCLICACPMPYPSNNFALSC-DLSENGSLISCNCQPGYGG 1849
++ + V + + C CP + + D S L C G
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG 553
Query: 1850 ARCEYCAAGYYGI--PEDTDLHTGDYCKPCNCSGNINPQ----DPGSCDSINGD------ 1897
C+ CA G+ G+ E+ D D C C I+ +PG +I D
Sbjct: 554 YECQ-CATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 1898 ---CL---KCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
CL +C++ G CN C PG G I +C + C G+ +CVC
Sbjct: 613 SSPCLNDGRCIDLVNGYQCN-CQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVC 670
Query: 1950 RPGVIGEKC----DRCA--PDHWGLN--TGLGCTPCNCGIASESTQCDDDNGQC------ 1995
PG G++C D CA P G G+ C C C +C
Sbjct: 671 SPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 1996 --RCAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVI 2049
C G++G +C C AG+ K+ C C G + + N +C C G
Sbjct: 731 HGNCTGGLSGYKC-LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY-RCTCKKGFK 788
Query: 2050 GEKCDRCPERWVLIPQEGCLECDSCTD 2076
G C + P CL +C D
Sbjct: 789 GYNCQVNIDECASNP---CLNQGTCFD 812
Score = 52.4 bits (120), Expect = 3e-05
Identities = 93/374 (24%), Positives = 125/374 (33%), Gaps = 67/374 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G C ++ + PC +G D+ G NC T G +CE
Sbjct: 593 CICNPGYMGAICSD------QIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVNCEI 644
Query: 1796 ----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C S HG G R +C+ N + + + N C G G
Sbjct: 645 NFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID-ECASNPCRKGATCINGVNG 703
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPC---NCSGNINPQ----DPG----SCDSINGDC 1898
RC C G + P PC NC+G ++ D G +C+ +C
Sbjct: 704 FRC-ICPEGPHH-PSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
Query: 1899 LK--------CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
L C N G C C GF G NC I DE C GTC
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCT-CKKGFKG-----YNCQVNI-DECASNPC-LNQGTCF-- 811
Query: 1951 PGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----DNGQCRCAKGVTGKQC 2006
+ G C C + G N PC+ + C + ++ C CA G G++C
Sbjct: 812 DDISGYTC-HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Query: 2007 DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCDRCPERWVLIP 2064
T D D C + G N G CEC PG G C+ + + P
Sbjct: 871 ----------TID-IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 2065 QEGCLECDSCTDAL 2078
C SC D +
Sbjct: 920 ---CQNGGSCMDGV 930
Score = 48.0 bits (109), Expect = 6e-04
Identities = 73/295 (24%), Positives = 108/295 (36%), Gaps = 67/295 (22%)
Query: 1766 QCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNN 1825
QC + C VN G+C+ + T +C+ C G+ G+ C P N
Sbjct: 27 QCRDGYEPC-VNEGMCVTYHNGT--GYCK-CPEGFLGE----------YCQHRDPCEKNR 72
Query: 1826 FALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC---KPCNCSGN 1882
C +NG +C Q G A C CA+G+ G ED T C +PC
Sbjct: 73 ----C---QNGG--TCVAQAMLGKATCR-CASGFTG--EDCQYSTSHPCFVSRPC----- 115
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTACICDEFGMADCD 1941
+ G+C ++ D +C C GF G + ++ C + C
Sbjct: 116 ---LNGGTCHMLSRDTYECT----------CQVGFTGKECQWTDACLSHPCANGSTCTTV 162
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKG 2000
+ +C C G G+KC+ + C P +C QC+C +G
Sbjct: 163 ANQFSCKCLTGFTGQKCETDVNE---------CDIPGHCQHGGTCLNLPGSY-QCQCPQG 212
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
TG+ CD Y C C G + + T +C CLPG G C+R
Sbjct: 213 FTGQYCDSL------YVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 27/149 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNC--RPCHCPSTAICDDNGM-CICPKNVEGENC-DRC 1414
C C P G+ C+ C PC +T I NG CICP+ +C +
Sbjct: 668 CVCSPGFTGQRCNI------DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Query: 1415 KPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
N + C C C+ G VG + CE D +C G CD+ V G
Sbjct: 722 NECLSNPCIHGNCTGGLSGYKCLCDA-GWVG--INCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Y+CTC + Y+ C N +C
Sbjct: 779 -------YRCTCKKGFKGYN-CQVNIDEC 799
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/181 (25%), Positives = 62/181 (34%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCR--PCHCP 1389
C C +G T C +C P G TCS C GY G NC C
Sbjct: 1135 CQCP-LGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGV-NCEYEVDECQ 1192
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
+ C + G CI V C C P T + DDC P + G Q
Sbjct: 1193 NQP-CQNGGTCI--DLVNHFKCS-CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C C G C+ + +C C+ G+ + N C C++ G+ C+
Sbjct: 1249 SCRCLPGFAGERCEGDI------NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Query: 1510 T 1510
T
Sbjct: 1303 T 1303
Score = 44.0 bits (99), Expect = 0.010
Identities = 47/191 (24%), Positives = 69/191 (36%), Gaps = 16/191 (8%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPC--HCPSTAICDDNGMCICPKNVEGENCDRCKP 1416
C PN TC C G+ G C C S C ++G+C N +G C P
Sbjct: 848 CKESPNFESYTC-LCAPGWQG-QRCTIDIDECISKP-CMNHGLC---HNTQGSYMCECPP 901
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
D + DDC NP G+ + ++ C C G C + + P
Sbjct: 902 GFSGMDCEEDIDDCLANPCQNGGSCMD-GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
Query: 1477 QCTCNRHGTTYDV-CDQNTAQCYCKTNVR---GQAC---DTCKEEYFNLQDDNPDGCTKC 1529
TC+ + +Y C +C+ N+ +C TC + + P G T
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS 1020
Query: 1530 FCFGKTTRCSS 1540
FC + CSS
Sbjct: 1021 FCLHEINECSS 1031
Score = 41.5 bits (93), Expect = 0.056
Identities = 51/184 (27%), Positives = 66/184 (35%), Gaps = 26/184 (14%)
Query: 1336 GARPCLC--DFMG-STELECNTFGGQCPCKPN-----VIGRTCSACRTGYYGFPNCRPC- 1386
G CLC F G ELE N PC N + R C G+ G P C+
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQCVDKVNRFQCLCPPGFTG-PVCQIDI 533
Query: 1387 -HCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C ST C + CI N G C +T + D+C+ +P Q Q
Sbjct: 534 DDCSSTP-CLNGAKCIDHPN--GYECQCATGFT-GVLCEENIDNCDPDPCH--HGQCQDG 587
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRG 1505
DS C C G +C + +CY C G D+ N QC C+ G
Sbjct: 588 IDSYTCICNPGYMGAICSDQI------DECYSSPCLNDGRCIDLV--NGYQCNCQPGTSG 639
Query: 1506 QACD 1509
C+
Sbjct: 640 VNCE 643
Score = 40.3 bits (90), Expect = 0.13
Identities = 58/228 (25%), Positives = 75/228 (32%), Gaps = 28/228 (12%)
Query: 1757 LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICA 1816
+P GF C +C + G + C G+ C SG +PRDC
Sbjct: 1325 MPDGFICRCPPGFSGARCQSSCGQ-VKCRK---GEQCVHTASGPR--CFCPSPRDCESGC 1378
Query: 1817 CPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
P SC SC C P + G+RCE A P T L YC
Sbjct: 1379 ASSPCQHGG---SCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCL--SQYCAD 1432
Query: 1877 CNCSGNINPQ-DPGSCDSINGDC-LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICD 1933
G + + +C GDC L N A + L C N C+ D
Sbjct: 1433 KARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFD 1492
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN-TGLGCTPCNCG 1980
F +C + TC K D+ DH+ N GC CG
Sbjct: 1493 NF---ECQGNSKTC---------KYDKYCADHFKDNHCDQGCNSEECG 1528
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/212 (21%), Positives = 73/212 (34%), Gaps = 14/212 (6%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEG 415
C+C P FS C+ G+ +CR Q +S + P C C G+
Sbjct: 1331 CRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
Query: 416 EHCTPTDGLCPCKYNYAGKSCEICEDGYYSP--ECKNCECNTVGSVSYVCDKLTGDCTCK 473
P C C ++G CE+ +P C + C VCD+ C
Sbjct: 1391 PQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKAR-DGVCDEACNSHAC- 1448
Query: 474 SKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
++ G C+ + + N + PC + +C+ V +C+ C
Sbjct: 1449 -QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV--ECLFDNFECQGNSKTCKY 1505
Query: 533 GYYMQVLGRERQC-VPCNCDPTGSTSTSCSAD 563
Y ++ C CN + G C+AD
Sbjct: 1506 DKYCADHFKDNHCDQGCNSEECGWDGLDCAAD 1537
Score = 35.5 bits (78), Expect = 3.6
Identities = 51/216 (23%), Positives = 74/216 (34%), Gaps = 30/216 (13%)
Query: 1301 REFIEQCASYNYYIS-PNETGLCREAMFSITSEYNSGARPC---LCDFMGSTELECNTFG 1356
R+ E C + ++ N TG C+ EY PC C G+ +
Sbjct: 29 RDGYEPCVNEGMCVTYHNGTGYCK-CPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 87
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA--ICDDNGMCICPKNVEGENCDRC 1414
C C G C T + F + RPC T + D C C G+ C
Sbjct: 88 ATCRCASGFTGEDCQYS-TSHPCFVS-RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-- 143
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD 1474
+T + + C N + V NQ C+ +G + CD +PGH
Sbjct: 144 --WT-DACLSHPC--ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD--IPGH----- 191
Query: 1475 CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C GT ++ + QC C GQ CD+
Sbjct: 192 -----CQHGGTCLNL--PGSYQCQCPQGFTGQYCDS 220
Score = 35.1 bits (77), Expect = 4.8
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 21/226 (9%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRPCHCPST 1391
CLC G T +C T +C +P G TCS C+ G+ G + +
Sbjct: 935 CLC-LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
Query: 1392 AICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG-- 1449
+ C + G C+ + +C +T +F + ++C+ +P N+ C G
Sbjct: 994 SSCFNGGTCV--DGINSFSCLCPVGFTGSFCLHE-INECSSHP---CLNEGTCVDGLGTY 1047
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTC-NRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C+C G+ C V P + TC + + +C A YC +V +C
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC--DVPNVSC 1105
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSY-YTWAAIDEMVD 1553
D L + C G T C YT + +E +D
Sbjct: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 78.2 bits (184), Expect = 5e-13
Identities = 114/445 (25%), Positives = 158/445 (35%), Gaps = 67/445 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C P FS +CEE+ C P C D N C C L G G+ C
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSC-------MDGVNTFSCLC-LPGFTGDKCQT 948
Query: 421 TDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
C PCK G +C + Y C+C G C+ +CT S ++
Sbjct: 949 DMNECLSEPCK---NGGTCSDYVNSY------TCKCQ-AGFDGVHCENNINECTESSCFN 998
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI----CKAGFGGPRCDQCLSG 533
G TC G ++ P S I + S C+ C G G RC C G
Sbjct: 999 GGTCVD---GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLG 1054
Query: 534 YY-MQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Y C C G T A+ +C C + + GA CD P +
Sbjct: 1055 YTGKNCQTLVNLCSRSPCKNKG-TCVQKKAESQCLCPSGWAGAYCD--------VP---N 1102
Query: 593 CNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGV 645
+CD++ S + C +G+C N +C Y +EC +P G
Sbjct: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGA 1162
Query: 646 TAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
T S F G C VP + C+ V C+ + N F C C G L
Sbjct: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC-SCPPGTRGLL 1221
Query: 702 --NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSI 754
++ C + C+ C +G C +CL GF + D+ C C GS+
Sbjct: 1222 CEENIDDC-ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 755 DNNCDKTTGQ--CHCHSRVEGRRCD 777
D C + T C C S GR C+
Sbjct: 1280 D--CIQLTNDYLCVCRSAFTGRHCE 1302
Score = 75.8 bits (178), Expect = 3e-12
Identities = 133/575 (23%), Positives = 192/575 (33%), Gaps = 78/575 (13%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C+C G C + + Q D C C+ +IDE S
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 314 DIN-GR---YEGGGKCLNCQHNTEGINCN-KCRPTYYRP--YGKRWDELDVCQPCQCDPH 366
+N GR G +C NCQ T G+NC P +G D ++ C C P
Sbjct: 616 CLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS-CVCSPG 673
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----DYPNCKPCTCNLNGTEGEHCTP-- 420
F+ C + C P + C + G+ + P+ C +N C
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Query: 421 -TDGL----CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
T GL C C + G +CE+ ++ EC + C G+ CD L CTCK
Sbjct: 734 CTGGLSGYKCLCDAGWVGINCEVDKN-----ECLSNPCQNGGT----CDNLVNGYRCTCK 784
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLS 532
+ G C N C C GT DD+SG C C + G C L+
Sbjct: 785 KGFKGYNCQ------VNIDECASNPCLNQGT---CFDDISGYTCHCVLPYTGKNCQTVLA 835
Query: 533 GYYMQVLGRERQC--------VPCNCDPTGSTSTSCSAD-GKC---NCLT-----NFGGA 575
C C C P G C+ D +C C+ N G+
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAP-GWQGQRCTIDIDECISKPCMNHGLCHNTQGS 894
Query: 576 QCDQCSPGYY------KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
+C PG+ DCL+ C GS + C C F G KC T +
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS-CLCLPGFTGDKCQTDMNEC 953
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ P C V + C + G C++ + + C + N F
Sbjct: 954 LSEPCKNGGTCSDY-VNSYTCKCQAGFDG--VHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 690 CEQCNCNLAGT--LNSLGACNTKS--GQCVCKQHVGERQCDQCLDGFYRLQTNDVFG-CT 744
C C G+ L+ + C++ + C +G +C C G+ + C+
Sbjct: 1011 C-LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCS 1068
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C G+ K QC C S G CD P
Sbjct: 1069 RSPCKNKGTCVQK--KAESQCLCPSGWAGAYCDVP 1101
Score = 71.3 bits (167), Expect = 6e-11
Identities = 137/575 (23%), Positives = 199/575 (34%), Gaps = 103/575 (17%)
Query: 254 CRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
C CQ G +C + C S + ++FSC+ C T + +++E
Sbjct: 131 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK---CLTGFTGQKCETDVNE-- 185
Query: 311 LSLDINGRYEGGGKCLN--------CQHNTEGINCNK----CRPTYYRPYGKRWDELDVC 358
DI G + GG CLN C G C+ C P+ G D
Sbjct: 186 --CDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG---TEG 415
C C P F CE C P + + C G Y NC+ C G TE
Sbjct: 244 FECNCLPGFEGSTCERNIDDC---PNHRCQNGGVCVDGVNTY-NCR-CPPQWTGQFCTED 298
Query: 416 -EHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECK----NCECNTVGSVSYVCDKL 466
+ C C C G C +C +G+ +C +C + S D++
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGC-VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 467 TG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
C C +G C+ A N P K CDT + ++GQ C C G+
Sbjct: 358 ASFSCMCPEGKAGLLCHLDDACISN-PCHKGALCDT--------NPLNGQYICTCPQGYK 408
Query: 524 GPRC----DQCL---------SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSAD 563
G C D+C +G + G +C+ C D S C D
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD 623
CL GG C C PG+ + C +++ + C +NG C K N +C
Sbjct: 469 --ATCLDKIGGFTC-LCMPGF----KGVHCELEINECQSNPCVNNGQCVDKVN--RFQC- 518
Query: 624 TCREQFYNYPAC----EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
C F P C ++C+ P + A C P G CQC G +C +
Sbjct: 519 LCPPGFTG-PVCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEE----- 569
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL-DGFYRLQTN 738
N+ +P C C G + CN +C + E CL DG +
Sbjct: 570 -NIDNCDPDPCHHGQCQ-DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDG----RCI 623
Query: 739 DVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
D+ +C+C G S NC+ C + + G
Sbjct: 624 DLVNGYQCNCQPGTS-GVNCEINFDDCASNPCIHG 657
Score = 69.7 bits (163), Expect = 2e-10
Identities = 98/353 (27%), Positives = 138/353 (39%), Gaps = 73/353 (20%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C CP+ Y+G C + + S PC+ H+ +C VNT D HCE
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSN---PCE---HAGKC-VNT-------DGAF--HCE- 443
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C+ GY G +C P N A +C L + G +C C PG+ G CE
Sbjct: 444 CLKGYAGPRCEMDINEC------HSDPCQNDA-TC-LDKIGG-FTCLCMPGFKGVHCELE 494
Query: 1855 ---CAAG-YYGIPEDTDLHTGDYCK-PCNCSGNINPQDPGSCDS---INGDCLKCVNNTA 1906
C + + D C P +G + D C S +NG KC+++
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG--AKCIDHPN 552
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDS--TTGTCVCRPGVIGEKCDRCAPD 1964
G C CA GF G + +N C D C + TC+C PG +G C +
Sbjct: 553 GYECQ-CATGFTG-VLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQC----DQCAAG--FWNYT 2017
+ +PC ++ D NG QC C G +G C D CA+
Sbjct: 611 CYS-------SPC----LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGIC 659
Query: 2018 KDGCDH--CNCNTGYSVGFMCN------ATGQCE----CLPGVIGEKCDRCPE 2058
DG + C C+ G++ G CN A+ C C+ GV G +C CPE
Sbjct: 660 MDGINRYSCVCSPGFT-GQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPE 710
Score = 67.7 bits (158), Expect = 7e-10
Identities = 99/380 (26%), Positives = 134/380 (35%), Gaps = 77/380 (20%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCV------PCQC-NGHSD-QCDVNTGICLNC 1784
C CP Y G +C+ R P G CV C C +G + CDV C +
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DI 1107
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNC 1843
A + G E H + + C CP+ Y + D + N C
Sbjct: 1108 AASRRGVLVEHLCQ--HSGVCINA-GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYC--KPC----NCSGNIN----PQDPGS--- 1890
GG RCE C GY G+ + ++ D C +PC C +N PG+
Sbjct: 1165 SDFIGGYRCE-CVPGYQGVNCEYEV---DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL 1220
Query: 1891 -CDSINGDCLK---------CVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMA 1938
C+ DC + C++ G +C C PGF G+ C + C G
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCR-CLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 1939 DCDSTTG--TCVCRPGVIGEKCDR---CAPDHWGLNTGLGCTP--------CNCGIASES 1985
DC T CVCR G C+ P LN G C C
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAG---FWNYTKD---GCDHCNCNTGYSVGFMCNAT 2039
+C GQ +C K G+QC A+G F +D GC C G S C+
Sbjct: 1340 ARCQSSCGQVKCRK---GEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGS----CHPQ 1392
Query: 2040 GQ-----CECLPGVIGEKCD 2054
Q C+C P G +C+
Sbjct: 1393 RQPPYYSCQCAPPFSGSRCE 1412
Score = 66.1 bits (154), Expect = 2e-09
Identities = 137/570 (24%), Positives = 193/570 (33%), Gaps = 96/570 (16%)
Query: 258 HNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC----NCHN--HTTECTYDPEIDEKRL 311
HNT G +C GF ++ D PC +C + +T C P +
Sbjct: 889 HNTQGSYMCECPPGFSGMD--CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Query: 312 SLDINGRY----EGGGKCLN--------CQHNTEGINC----NKCRPTYYRPYGKRWDEL 355
D+N + GG C + CQ +G++C N+C + G D +
Sbjct: 947 QTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI 1006
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEG 415
+ C C F+ C E C P +C G Y C+C L G G
Sbjct: 1007 NSFS-CLCPVGFTGSFCLHEINECSSHPCLNE---GTCVDGLGTYR----CSCPL-GYTG 1057
Query: 416 EHCTPTDGLC---PCKYN--YAGKSCE---ICEDGYYSPECK--NCECNTVGSVSYVCDK 465
++C LC PCK K E +C G+ C N C+ S V
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV- 1116
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC----ICKAG 521
+ C+ +SG N AG +Y C P S E + + S C C
Sbjct: 1117 ---EHLCQ--HSGVCIN---AGNTHYCQC-PLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNFGGAQCDQ 579
GG RC+ C+ GY Q + E + C P G T KC+C G C++
Sbjct: 1168 IGGYRCE-CVPGY--QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 1224
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDN--GL-CHCKSNFDGAKCDTCREQFYNYPACE 636
+ P CL+ G C D G C C F G +C+ + + P
Sbjct: 1225 NIDDCARGPHCLN---------GGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 637 ECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
E + D C + LC C+ GR C + + N C +
Sbjct: 1276 EGSLD----------CIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
Query: 697 LAGTL-----NSLGA-CNTKSGQCVCKQHVGERQCDQCLDG---FYRLQTNDVFGCTECD 747
G + GA C + GQ C++ GE QC G F + GC
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVKCRK--GE-QCVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 748 CDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C GGS C C G RC+
Sbjct: 1383 CQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
Score = 64.9 bits (151), Expect = 5e-09
Identities = 115/482 (23%), Positives = 161/482 (33%), Gaps = 65/482 (13%)
Query: 325 CLNCQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
CLN +G+ +C P Y GK L C P + G C ++ +C
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYT--GKNCQTL--VNLCSRSPCKNKGTCVQKKAESQC-- 1087
Query: 384 EFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P S A Y D PN + G EH G+C N C + G
Sbjct: 1088 -LCP---SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Query: 443 YYSPE-CKNCECNTVGSVSYVCDKLTG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCD 500
Y E C N + D + G C C Y G C Y C+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE------YEVDECQNQPCQ 1197
Query: 501 TSGTEPSICDDVSG--QCICKAGFGGPRCDQ----------CLSGYYM--QVLGRERQCV 546
GT C D+ +C C G G C++ CL+G ++ G +C+
Sbjct: 1198 NGGT----CIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCL 1253
Query: 547 P------CNCDPTGSTSTSCSADGKCNC--LTNFGGAQCDQCSPGYY--KYPD-CLSCNC 595
P C D S CS++G +C LTN C G + + D C C
Sbjct: 1254 PGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPC 1313
Query: 596 DVSGS--IGSTCDDNGLCHCKSNFDGAKC-DTCRE-QFYNYPACEECNCDPRGVTASFAG 651
G+ + S D +C C F GA+C +C + + C PR S
Sbjct: 1314 LNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 652 CGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNT- 709
C S A CQ G C+ +P Y++ Q PF +C A C +
Sbjct: 1374 CESGCASSPCQ-----HGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 710 ----KSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
K+ VC + C Q G L + + I+N CD+
Sbjct: 1429 YCADKARDGVCDEACNSHAC-QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV 1487
Query: 766 HC 767
C
Sbjct: 1488 EC 1489
Score = 64.5 bits (150), Expect = 7e-09
Identities = 112/468 (23%), Positives = 162/468 (34%), Gaps = 84/468 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSS--------CAYGY------FDYPNCKPC 406
C C P F +CE E C+ P C C G+ D +C
Sbjct: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 407 TCNLNGTEG-EHCTPTDGLCPCKYNYAGKSCE----ICE-DGYYSPECKN------CECN 454
C LNG + +H P C C + G CE C+ D + +C++ C CN
Sbjct: 540 PC-LNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN 596
Query: 455 TVGSVSYVCDKLTGDC---------TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE 505
G + +C +C C +G CN CQ G C+ N D +
Sbjct: 597 P-GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN-CQPGTSGV-NCE-INFDDCASN 652
Query: 506 P---SICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTG 554
P IC D + C+C GF G RC+ + + C+ C C P G
Sbjct: 653 PCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCIC-PEG 711
Query: 555 STSTSC-SADGKC--------NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC 605
SC S +C NC G +C C G+ ++C D + + + C
Sbjct: 712 PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC-LCDAGWVG----INCEVDKNECLSNPC 766
Query: 606 DDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQ 662
+ G C N G +C TC++ F Y +EC +P + C +G C
Sbjct: 767 QNGGTCDNLVN--GYRC-TCKKGFKGYNCQVNIDECASNP---CLNQGTCFDDISGYTCH 820
Query: 663 CKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG----ACNTKSGQCVCK 717
C G+ C P N E E N L + G C +C+ K
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 718 QHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
+ C G Y + F +C+ DI + N C + G C
Sbjct: 881 PCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPC-QNGGSC 926
Score = 63.3 bits (147), Expect = 2e-08
Identities = 102/408 (25%), Positives = 139/408 (34%), Gaps = 94/408 (23%)
Query: 1735 ECQCPRAYRGLSCEQCAE---GHYRLPSGFCVP------CQ---------CNGHSDQCDV 1776
EC C + G +CE+ + H G CV C+ C D+C +
Sbjct: 245 ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304
Query: 1777 NTGICLN---CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPS----NNFALS 1829
C N CA+ G C C++G+ GD DC +C +F+
Sbjct: 305 QPNACQNGGTCANRNGGYGC-VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCM 363
Query: 1830 CDLSENGSLI----SCNCQPGYGGARCE----------YCAAGYYG--IPEDTDLHTGDY 1873
C + G L +C P + GA C+ C GY G ED D
Sbjct: 364 CPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMAN 423
Query: 1874 CKPCNCSGN-INPQDPGSCDSING-----------DC--------LKCVNNTAGAACNLC 1913
PC +G +N C+ + G +C C++ G C LC
Sbjct: 424 SNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC-LC 482
Query: 1914 APGFYG--DAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTG 1971
PGF G + C + C G C+C PG G C D
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDD------- 535
Query: 1972 LGCTPCNCGIASESTQC-DDDNG-QCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTG 2029
TPC G +C D NG +C+CA G TG C++ N D C H C G
Sbjct: 536 CSSTPCLNG-----AKCIDHPNGYECQCATGFTGVLCEE---NIDNCDPDPCHHGQCQDG 587
Query: 2030 YSVGFMCNATGQCECLPGVIGEKC-DRCPERWVLIPQEGCLECDSCTD 2076
+ C C PG +G C D+ E + CL C D
Sbjct: 588 ID-------SYTCICNPGYMGAICSDQIDECY----SSPCLNDGRCID 624
Score = 62.5 bits (145), Expect = 3e-08
Identities = 98/370 (26%), Positives = 130/370 (35%), Gaps = 77/370 (20%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
P C GY N C NGT G C C + G+ C+ +
Sbjct: 22 PAHALQCRDGYEPCVNEGMCVTYHNGT---------GYCKCPEGFLGEYCQ------HRD 66
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC----NCDTS 502
C+ C G+ V + G TC+ SG T CQ Y T PC C
Sbjct: 67 PCEKNRCQNGGTC--VAQAMLGKATCRCA-SGFTGEDCQ-----YSTSHPCFVSRPCLNG 118
Query: 503 GTEPSICDDVSGQCICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
GT + D +C C+ GF G C D CLS PC GST T+
Sbjct: 119 GTCHMLSRDTY-ECTCQVGFTGKECQWTDACLSH-------------PC---ANGSTCTT 161
Query: 560 CSADGKCNCLTNFGGAQCD----QCS-PGYYKY-------PDCLSCNCDVSGSIGSTCDD 607
+ C CLT F G +C+ +C PG+ ++ P C C + G G CD
Sbjct: 162 VANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDS 220
Query: 608 NGL-CHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTA--SFAGCGSVPAGELCQ 662
+ C +G TCR+ ECNC P G T + C +
Sbjct: 221 LYVPCAPSPCVNGG---TCRQ---TGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGV 274
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG--QCVCKQHV 720
C D V C C P W Q + ++C N G C ++G CVC
Sbjct: 275 CVDGVNTYNCR-CPP-QWTGQ-FCTEDVDECLLQPNACQNG-GTCANRNGGYGCVCVNGW 330
Query: 721 GERQCDQCLD 730
C + +D
Sbjct: 331 SGDDCSENID 340
Score = 62.1 bits (144), Expect = 4e-08
Identities = 90/342 (26%), Positives = 125/342 (36%), Gaps = 64/342 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC G +C+ G+ GF C + D+C N CLN C D+ G
Sbjct: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGF-KGYNCQVNIDECASNP--CLNQGTCFDDISG 816
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C C+ Y G ++C P P P N A+ C S N +C C PG+ G
Sbjct: 817 YTCH-CVLPYTG-------KNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQG 867
Query: 1850 ARC----EYCAAG---YYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--- 1899
RC + C + +G+ +T G Y C C + D C+ DCL
Sbjct: 868 QRCTIDIDECISKPCMNHGLCHNTQ---GSYM--CECPPGFSGMD---CEEDIDDCLANP 919
Query: 1900 -----KCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGTCVCRPG 1952
C++ +C LC PGF GD + C + C G + TC C+ G
Sbjct: 920 CQNGGSCMDGVNTFSC-LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAA 2011
G C+ +N CT +C + T D N C C G TG C
Sbjct: 979 FDGVHCEN------NINE---CTESSC--FNGGTCVDGINSFSCLCPVGFTGSFC----- 1022
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+ + H N G V + T +C C G G+ C
Sbjct: 1023 --LHEINECSSHPCLNEGTCVDGL--GTYRCSCPLGYTGKNC 1060
Score = 61.7 bits (143), Expect = 5e-08
Identities = 99/429 (23%), Positives = 150/429 (34%), Gaps = 74/429 (17%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYAGKSC 436
C C ++ DC+ D C N G+ C TDG C C YAG C
Sbjct: 401 CTCPQGYKGADCTE------DVDECAMANSNPCEHAGK-CVNTDGAFHCECLKGYAGPRC 453
Query: 437 EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
E+ + +S C+N D TC K G TC C G+
Sbjct: 454 EMDINECHSDPCQN------------------DATCLDKIGGFTC-LCMPGFKGV----H 490
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C + + + + C + +GQC+ K C +G Q+ + PC G+
Sbjct: 491 CELEINECQSNPCVN-NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC---LNGAK 546
Query: 557 STSCSADGKCNCLTNFGGAQC----DQCSPGYYKYPDC------LSCNCDVSGSIGSTCD 606
+C C T F G C D C P + C +C C+ G +G+ C
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN-PGYMGAICS 605
Query: 607 DN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTA--SFAGCGSVPAGELC 661
D C+ + +C + +CNC P GV +F C S P
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGY-------QCNCQPGTSGVNCEINFDDCASNPCIHGI 658
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG-QCVCKQHV 720
C D + C C P + Q N ++C N N +G +C+C +
Sbjct: 659 -CMDGINRYSC-VCSPGFTG-QRCN-IDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
Query: 721 GERQC----DQCLDG--FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
C ++CL + T + G +C CD G + NC+ +C + G
Sbjct: 713 HHPSCYSQVNECLSNPCIHGNCTGGLSG-YKCLCD-AGWVGINCEVDKNECLSNPCQNGG 770
Query: 775 RCDQPIRAH 783
CD + +
Sbjct: 771 TCDNLVNGY 779
Score = 61.3 bits (142), Expect = 6e-08
Identities = 86/344 (25%), Positives = 114/344 (33%), Gaps = 42/344 (12%)
Query: 1733 VEECQC-PRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
+ ECQ P G ++ P GF P C D C CLN C D+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPV-CQIDIDDCSSTP--CLNGAKCIDHP 551
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C +G+ G +C P P ++ + +C C PGY
Sbjct: 552 NGYECQ-CATGFTGVLCEENIDNC------DPDPCHHGQCQDGIDS----YTCICNPGYM 600
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK--PCNC----SG---NINPQDPGSCDSINGDCL 1899
GA C Y P D D CNC SG IN D S I+G C+
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TCVCRPGVIGE 1956
+N + C +C+PGF G I C + C + G + G C+C G
Sbjct: 661 DGINRYS---C-VCSPGFTGQRCNIDIDECASNPCRK-GATCINGVNGFRCICPEGPHHP 715
Query: 1957 KC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
C + C + H GL C C C+ D +C G CD
Sbjct: 716 SCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL 775
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G+ K G NC Q C + G C
Sbjct: 776 VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
Score = 60.1 bits (139), Expect = 1e-07
Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 46/304 (15%)
Query: 1784 CADNTI-GDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C N + G + C GY G D T D CA P + A C ++ +G+ C
Sbjct: 390 CDTNPLNGQYICTCPQGYKGADCT----EDVDECAMANSNPCEH-AGKC-VNTDGAF-HC 442
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGD-------YCKP----CNCSGNINPQDPGS 1890
C GY G RCE + P D D C P +C IN
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TC 1947
C + NG C+ VN C LC PGF G I +C++ C G D G C
Sbjct: 503 CVN-NGQCVDKVNRFQ---C-LCPPGFTGPVCQIDIDDCSSTPCLN-GAKCIDHPNGYEC 556
Query: 1948 VCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C G G C D C PD H G+ C C C D +C +
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYS--------VGFMCNATGQ--CECLPGVIG 2050
+ +C G+ + G NC + G + + C C PG G
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 2051 EKCD 2054
++C+
Sbjct: 677 QRCN 680
Score = 56.4 bits (130), Expect = 2e-06
Identities = 83/312 (26%), Positives = 117/312 (37%), Gaps = 58/312 (18%)
Query: 1766 QCNGHSDQCDV-----NTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMP 1820
+C ++CD+ + G CLN + C+ C+ G+ G D L C P
Sbjct: 178 KCETDVNECDIPGHCQHGGTCLNLPGSY---QCQ-CLQGFTGQYC-----DSLYVPCA-P 227
Query: 1821 YPSNNFALSCDLSENGSLISCNCQPGYGGARCE---------YCAAGYYGIPEDTDLHTG 1871
P N +C + + + CNC PG+ G+ CE C G G+ D ++T
Sbjct: 228 SPCVNGG-TCRQTGDFTF-ECNCLPGFEGSTCERNIDDCPNHRCQNG--GVCVD-GVNTY 282
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSKNCT 1928
+ P +G +D C C C N G C +C G+ GD +C+
Sbjct: 283 NCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGC-VCVNGWSGD-----DCS 336
Query: 1929 ACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC 1988
I D+ A C + TC+ R V C C GL L C + C
Sbjct: 337 ENI-DDCAFASC-TPGSTCIDR--VASFSC-MCPEGKAGLLCHLD-DACISNPCHKGALC 390
Query: 1989 DDD--NGQ--CRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATG--QC 2042
D + NGQ C C +G G C + D C N N G N G C
Sbjct: 391 DTNPLNGQYICTCPQGYKGADCTE--------DVDECAMANSNPCEHAGKCVNTDGAFHC 442
Query: 2043 ECLPGVIGEKCD 2054
ECL G G +C+
Sbjct: 443 ECLKGYAGPRCE 454
Score = 54.4 bits (125), Expect = 7e-06
Identities = 85/334 (25%), Positives = 114/334 (34%), Gaps = 44/334 (13%)
Query: 1753 GHYRLPSGFCVP-CQCNGHSDQCDVNT----GICLNCADNTIGDHCEFCMSGYHG-DATV 1806
G+ + P GF CQ H D C+ N G C+ A +G C SG+ G D
Sbjct: 49 GYCKCPEGFLGEYCQ---HRDPCEKNRCQNGGTCV--AQAMLGKATCRCASGFTGEDCQY 103
Query: 1807 GTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC-AAGYYGIPED 1865
T C + P LS D E C CQ G+ G C++ A +
Sbjct: 104 STSHPCFVSR-PCLNGGTCHMLSRDTYE------CTCQVGFTGKECQWTDACLSHPCANG 156
Query: 1866 TDLHTGDYCKPCNC----SGNINPQDPGSCDSINGDCL---KCVNNTAGAACNLCAPGF- 1917
+ T C C +G D CD I G C C+N C C GF
Sbjct: 157 STCTTVANQFSCKCLTGFTGQKCETDVNECD-IPGHCQHGGTCLNLPGSYQCQ-CLQGFT 214
Query: 1918 --YGDAIFSKNCTACICDEFGMA-DCDSTTGTCVCRPGVIGEKCDR---CAPDHWGLNTG 1971
Y D+++ C C G T C C PG G C+R P+H N G
Sbjct: 215 GQYCDSLYVP-CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGG 273
Query: 1972 L---GCTPCNCGIASESTQ--CDDDNGQCRCAKGV--TGKQCDQCAAGFWNYTKDGCDHC 2024
+ G NC + T C +D +C G C G+ +G
Sbjct: 274 VCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
Query: 2025 NCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPE 2058
+C+ + T C+ V C CPE
Sbjct: 334 DCSENIDDCAFASCTPGSTCIDRVASFSC-MCPE 366
Score = 52.4 bits (120), Expect = 3e-05
Identities = 93/374 (24%), Positives = 125/374 (33%), Gaps = 67/374 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G C ++ + PC +G D+ G NC T G +CE
Sbjct: 593 CICNPGYMGAICSD------QIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVNCEI 644
Query: 1796 ----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C S HG G R +C+ N + + + N C G G
Sbjct: 645 NFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID-ECASNPCRKGATCINGVNG 703
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPC---NCSGNINPQ----DPG----SCDSINGDC 1898
RC C G + P PC NC+G ++ D G +C+ +C
Sbjct: 704 FRC-ICPEGPHH-PSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
Query: 1899 LK--------CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
L C N G C C GF G NC I DE C GTC
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCT-CKKGFKG-----YNCQVNI-DECASNPC-LNQGTCF-- 811
Query: 1951 PGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----DNGQCRCAKGVTGKQC 2006
+ G C C + G N PC+ + C + ++ C CA G G++C
Sbjct: 812 DDISGYTC-HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Query: 2007 DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCDRCPERWVLIP 2064
T D D C + G N G CEC PG G C+ + + P
Sbjct: 871 ----------TID-IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 2065 QEGCLECDSCTDAL 2078
C SC D +
Sbjct: 920 ---CQNGGSCMDGV 930
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 27/149 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNC--RPCHCPSTAICDDNGM-CICPKNVEGENC-DRC 1414
C C P G+ C+ C PC +T I NG CICP+ +C +
Sbjct: 668 CVCSPGFTGQRCNI------DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Query: 1415 KPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
N + C C C+ G VG + CE D +C G CD+ V G
Sbjct: 722 NECLSNPCIHGNCTGGLSGYKCLCDA-GWVG--INCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Y+CTC + Y+ C N +C
Sbjct: 779 -------YRCTCKKGFKGYN-CQVNIDEC 799
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/181 (25%), Positives = 62/181 (34%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCR--PCHCP 1389
C C +G T C +C P G TCS C GY G NC C
Sbjct: 1135 CQCP-LGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGV-NCEYEVDECQ 1192
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
+ C + G CI V C C P T + DDC P + G Q
Sbjct: 1193 NQP-CQNGGTCI--DLVNHFKCS-CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C C G C+ + +C C+ G+ + N C C++ G+ C+
Sbjct: 1249 SCRCLPGFAGERCEGDI------NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Query: 1510 T 1510
T
Sbjct: 1303 T 1303
Score = 44.0 bits (99), Expect = 0.010
Identities = 47/191 (24%), Positives = 69/191 (36%), Gaps = 16/191 (8%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPC--HCPSTAICDDNGMCICPKNVEGENCDRCKP 1416
C PN TC C G+ G C C S C ++G+C N +G C P
Sbjct: 848 CKESPNFESYTC-LCAPGWQG-QRCTIDIDECISKP-CMNHGLC---HNTQGSYMCECPP 901
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
D + DDC NP G+ + ++ C C G C + + P
Sbjct: 902 GFSGMDCEEDIDDCLANPCQNGGSCMD-GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
Query: 1477 QCTCNRHGTTYDV-CDQNTAQCYCKTNVR---GQAC---DTCKEEYFNLQDDNPDGCTKC 1529
TC+ + +Y C +C+ N+ +C TC + + P G T
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS 1020
Query: 1530 FCFGKTTRCSS 1540
FC + CSS
Sbjct: 1021 FCLHEINECSS 1031
Score = 41.5 bits (93), Expect = 0.056
Identities = 51/184 (27%), Positives = 66/184 (35%), Gaps = 26/184 (14%)
Query: 1336 GARPCLC--DFMG-STELECNTFGGQCPCKPN-----VIGRTCSACRTGYYGFPNCRPC- 1386
G CLC F G ELE N PC N + R C G+ G P C+
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQCVDKVNRFQCLCPPGFTG-PVCQIDI 533
Query: 1387 -HCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C ST C + CI N G C +T + D+C+ +P Q Q
Sbjct: 534 DDCSSTP-CLNGAKCIDHPN--GYECQCATGFT-GVLCEENIDNCDPDPCH--HGQCQDG 587
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRG 1505
DS C C G +C + +CY C G D+ N QC C+ G
Sbjct: 588 IDSYTCICNPGYMGAICSDQI------DECYSSPCLNDGRCIDLV--NGYQCNCQPGTSG 639
Query: 1506 QACD 1509
C+
Sbjct: 640 VNCE 643
Score = 40.3 bits (90), Expect = 0.13
Identities = 58/228 (25%), Positives = 75/228 (32%), Gaps = 28/228 (12%)
Query: 1757 LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICA 1816
+P GF C +C + G + C G+ C SG +PRDC
Sbjct: 1325 MPDGFICRCPPGFSGARCQSSCGQ-VKCRK---GEQCVHTASGPR--CFCPSPRDCESGC 1378
Query: 1817 CPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
P SC SC C P + G+RCE A P T L YC
Sbjct: 1379 ASSPCQHGG---SCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCL--SQYCAD 1432
Query: 1877 CNCSGNINPQ-DPGSCDSINGDC-LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICD 1933
G + + +C GDC L N A + L C N C+ D
Sbjct: 1433 KARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFD 1492
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN-TGLGCTPCNCG 1980
F +C + TC K D+ DH+ N GC CG
Sbjct: 1493 NF---ECQGNSKTC---------KYDKYCADHFKDNHCDQGCNSEECG 1528
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/212 (21%), Positives = 73/212 (34%), Gaps = 14/212 (6%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEG 415
C+C P FS C+ G+ +CR Q +S + P C C G+
Sbjct: 1331 CRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
Query: 416 EHCTPTDGLCPCKYNYAGKSCEICEDGYYSP--ECKNCECNTVGSVSYVCDKLTGDCTCK 473
P C C ++G CE+ +P C + C VCD+ C
Sbjct: 1391 PQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKAR-DGVCDEACNSHAC- 1448
Query: 474 SKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
++ G C+ + + N + PC + +C+ V +C+ C
Sbjct: 1449 -QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV--ECLFDNFECQGNSKTCKY 1505
Query: 533 GYYMQVLGRERQC-VPCNCDPTGSTSTSCSAD 563
Y ++ C CN + G C+AD
Sbjct: 1506 DKYCADHFKDNHCDQGCNSEECGWDGLDCAAD 1537
Score = 35.1 bits (77), Expect = 4.8
Identities = 51/216 (23%), Positives = 74/216 (34%), Gaps = 30/216 (13%)
Query: 1301 REFIEQCASYNYYIS-PNETGLCREAMFSITSEYNSGARPC---LCDFMGSTELECNTFG 1356
R+ E C + ++ N TG C+ EY PC C G+ +
Sbjct: 29 RDGYEPCVNEGMCVTYHNGTGYCK-CPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 87
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA--ICDDNGMCICPKNVEGENCDRC 1414
C C G C T + F + RPC T + D C C G+ C
Sbjct: 88 ATCRCASGFTGEDCQYS-TSHPCFVS-RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-- 143
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD 1474
+T + + C N + V NQ C+ +G + CD +PGH
Sbjct: 144 --WT-DACLSHPC--ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD--IPGH----- 191
Query: 1475 CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C GT ++ + QC C GQ CD+
Sbjct: 192 -----CQHGGTCLNL--PGSYQCQCLQGFTGQYCDS 220
Score = 35.1 bits (77), Expect = 4.8
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 21/226 (9%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRPCHCPST 1391
CLC G T +C T +C +P G TCS C+ G+ G + +
Sbjct: 935 CLC-LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
Query: 1392 AICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG-- 1449
+ C + G C+ + +C +T +F + ++C+ +P N+ C G
Sbjct: 994 SSCFNGGTCV--DGINSFSCLCPVGFTGSFCLHE-INECSSHP---CLNEGTCVDGLGTY 1047
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTC-NRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C+C G+ C V P + TC + + +C A YC +V +C
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC--DVPNVSC 1105
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSY-YTWAAIDEMVD 1553
D L + C G T C YT + +E +D
Sbjct: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 78.2 bits (184), Expect = 5e-13
Identities = 114/445 (25%), Positives = 158/445 (35%), Gaps = 67/445 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C P FS +CEE+ C P C D N C C L G G+ C
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSC-------MDGVNTFSCLC-LPGFTGDKCQT 948
Query: 421 TDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
C PCK G +C + Y C+C G C+ +CT S ++
Sbjct: 949 DMNECLSEPCK---NGGTCSDYVNSY------TCKCQ-AGFDGVHCENNINECTESSCFN 998
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI----CKAGFGGPRCDQCLSG 533
G TC G ++ P S I + S C+ C G G RC C G
Sbjct: 999 GGTCVD---GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLG 1054
Query: 534 YY-MQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Y C C G T A+ +C C + + GA CD P +
Sbjct: 1055 YTGKNCQTLVNLCSRSPCKNKG-TCVQKKAESQCLCPSGWAGAYCD--------VP---N 1102
Query: 593 CNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGV 645
+CD++ S + C +G+C N +C Y +EC +P G
Sbjct: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGA 1162
Query: 646 TAS-FAG---CGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTL 701
T S F G C VP + C+ V C+ + N F C C G L
Sbjct: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC-SCPPGTRGLL 1221
Query: 702 --NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSI 754
++ C + C+ C +G C +CL GF + D+ C C GS+
Sbjct: 1222 CEENIDDC-ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 755 DNNCDKTTGQ--CHCHSRVEGRRCD 777
D C + T C C S GR C+
Sbjct: 1280 D--CIQLTNDYLCVCRSAFTGRHCE 1302
Score = 75.8 bits (178), Expect = 3e-12
Identities = 133/575 (23%), Positives = 192/575 (33%), Gaps = 78/575 (13%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C+C G C + + Q D C C+ +IDE S
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 314 DIN-GR---YEGGGKCLNCQHNTEGINCN-KCRPTYYRP--YGKRWDELDVCQPCQCDPH 366
+N GR G +C NCQ T G+NC P +G D ++ C C P
Sbjct: 616 CLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS-CVCSPG 673
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----DYPNCKPCTCNLNGTEGEHCTP-- 420
F+ C + C P + C + G+ + P+ C +N C
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Query: 421 -TDGL----CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGD--CTCK 473
T GL C C + G +CE+ ++ EC + C G+ CD L CTCK
Sbjct: 734 CTGGLSGYKCLCDAGWVGINCEVDKN-----ECLSNPCQNGGT----CDNLVNGYRCTCK 784
Query: 474 SKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ-CICKAGFGGPRCDQCLS 532
+ G C N C C GT DD+SG C C + G C L+
Sbjct: 785 KGFKGYNCQ------VNIDECASNPCLNQGT---CFDDISGYTCHCVLPYTGKNCQTVLA 835
Query: 533 GYYMQVLGRERQC--------VPCNCDPTGSTSTSCSAD-GKC---NCLT-----NFGGA 575
C C C P G C+ D +C C+ N G+
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAP-GWQGQRCTIDIDECISKPCMNHGLCHNTQGS 894
Query: 576 QCDQCSPGYY------KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
+C PG+ DCL+ C GS + C C F G KC T +
Sbjct: 895 YMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS-CLCLPGFTGDKCQTDMNEC 953
Query: 630 YNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFG 689
+ P C V + C + G C++ + + C + N F
Sbjct: 954 LSEPCKNGGTCSDY-VNSYTCKCQAGFDG--VHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 690 CEQCNCNLAGT--LNSLGACNTKS--GQCVCKQHVGERQCDQCLDGFYRLQTNDVFG-CT 744
C C G+ L+ + C++ + C +G +C C G+ + C+
Sbjct: 1011 C-LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCS 1068
Query: 745 ECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQP 779
C G+ K QC C S G CD P
Sbjct: 1069 RSPCKNKGTCVQK--KAESQCLCPSGWAGAYCDVP 1101
Score = 71.7 bits (168), Expect = 5e-11
Identities = 137/575 (23%), Positives = 199/575 (34%), Gaps = 103/575 (17%)
Query: 254 CRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
C CQ G +C + C S + ++FSC+ C T + +++E
Sbjct: 131 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK---CLTGFTGQKCETDVNE-- 185
Query: 311 LSLDINGRYEGGGKCLN--------CQHNTEGINCNK----CRPTYYRPYGKRWDELDVC 358
DI G + GG CLN C G C+ C P+ G D
Sbjct: 186 --CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG---TEG 415
C C P F CE C P + + C G Y NC+ C G TE
Sbjct: 244 FECNCLPGFEGSTCERNIDDC---PNHRCQNGGVCVDGVNTY-NCR-CPPQWTGQFCTED 298
Query: 416 -EHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECK----NCECNTVGSVSYVCDKL 466
+ C C C G C +C +G+ +C +C + S D++
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGC-VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 467 TG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
C C +G C+ A N P K CDT + ++GQ C C G+
Sbjct: 358 ASFSCMCPEGKAGLLCHLDDACISN-PCHKGALCDT--------NPLNGQYICTCPQGYK 408
Query: 524 GPRC----DQCL---------SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSAD 563
G C D+C +G + G +C+ C D S C D
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD 623
CL GG C C PG+ + C +++ + C +NG C K N +C
Sbjct: 469 --ATCLDKIGGFTC-LCMPGF----KGVHCELEINECQSNPCVNNGQCVDKVN--RFQC- 518
Query: 624 TCREQFYNYPAC----EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
C F P C ++C+ P + A C P G CQC G +C +
Sbjct: 519 LCPPGFTG-PVCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEE----- 569
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL-DGFYRLQTN 738
N+ +P C C G + CN +C + E CL DG +
Sbjct: 570 -NIDNCDPDPCHHGQCQ-DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDG----RCI 623
Query: 739 DVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
D+ +C+C G S NC+ C + + G
Sbjct: 624 DLVNGYQCNCQPGTS-GVNCEINFDDCASNPCIHG 657
Score = 67.7 bits (158), Expect = 7e-10
Identities = 99/380 (26%), Positives = 134/380 (35%), Gaps = 77/380 (20%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP---SGFCV------PCQC-NGHSD-QCDVNTGICLNC 1784
C CP Y G +C+ R P G CV C C +G + CDV C +
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DI 1107
Query: 1785 ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNC 1843
A + G E H + + C CP+ Y + D + N C
Sbjct: 1108 AASRRGVLVEHLCQ--HSGVCINA-GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 1844 QPGYGGARCEYCAAGYYGIPEDTDLHTGDYC--KPC----NCSGNIN----PQDPGS--- 1890
GG RCE C GY G+ + ++ D C +PC C +N PG+
Sbjct: 1165 SDFIGGYRCE-CVPGYQGVNCEYEV---DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL 1220
Query: 1891 -CDSINGDCLK---------CVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMA 1938
C+ DC + C++ G +C C PGF G+ C + C G
Sbjct: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCR-CLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 1939 DCDSTTG--TCVCRPGVIGEKCDR---CAPDHWGLNTGLGCTP--------CNCGIASES 1985
DC T CVCR G C+ P LN G C C
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339
Query: 1986 TQCDDDNGQCRCAKGVTGKQCDQCAAG---FWNYTKD---GCDHCNCNTGYSVGFMCNAT 2039
+C GQ +C K G+QC A+G F +D GC C G S C+
Sbjct: 1340 ARCQSSCGQVKCRK---GEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGS----CHPQ 1392
Query: 2040 GQ-----CECLPGVIGEKCD 2054
Q C+C P G +C+
Sbjct: 1393 RQPPYYSCQCAPPFSGSRCE 1412
Score = 66.1 bits (154), Expect = 2e-09
Identities = 137/570 (24%), Positives = 193/570 (33%), Gaps = 96/570 (16%)
Query: 258 HNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC----NCHN--HTTECTYDPEIDEKRL 311
HNT G +C GF ++ D PC +C + +T C P +
Sbjct: 889 HNTQGSYMCECPPGFSGMD--CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
Query: 312 SLDINGRY----EGGGKCLN--------CQHNTEGINC----NKCRPTYYRPYGKRWDEL 355
D+N + GG C + CQ +G++C N+C + G D +
Sbjct: 947 QTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI 1006
Query: 356 DVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEG 415
+ C C F+ C E C P +C G Y C+C L G G
Sbjct: 1007 NSFS-CLCPVGFTGSFCLHEINECSSHPCLNE---GTCVDGLGTYR----CSCPL-GYTG 1057
Query: 416 EHCTPTDGLC---PCKYN--YAGKSCE---ICEDGYYSPECK--NCECNTVGSVSYVCDK 465
++C LC PCK K E +C G+ C N C+ S V
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV- 1116
Query: 466 LTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQC----ICKAG 521
+ C+ +SG N AG +Y C P S E + + S C C
Sbjct: 1117 ---EHLCQ--HSGVCIN---AGNTHYCQC-PLGYTGSYCEEQLDECASNPCQHGATCSDF 1167
Query: 522 FGGPRCDQCLSGYYMQVLGRERQCVPCNCDP--TGSTSTSCSADGKCNCLTNFGGAQCDQ 579
GG RC+ C+ GY Q + E + C P G T KC+C G C++
Sbjct: 1168 IGGYRCE-CVPGY--QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 1224
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDN--GL-CHCKSNFDGAKCDTCREQFYNYPACE 636
+ P CL+ G C D G C C F G +C+ + + P
Sbjct: 1225 NIDDCARGPHCLN---------GGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Query: 637 ECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCN 696
E + D C + LC C+ GR C + + N C +
Sbjct: 1276 EGSLD----------CIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
Query: 697 LAGTL-----NSLGA-CNTKSGQCVCKQHVGERQCDQCLDG---FYRLQTNDVFGCTECD 747
G + GA C + GQ C++ GE QC G F + GC
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVKCRK--GE-QCVHTASGPRCFCPSPRDCESGCASSP 1382
Query: 748 CDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C GGS C C G RC+
Sbjct: 1383 CQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
Score = 64.9 bits (151), Expect = 5e-09
Identities = 115/482 (23%), Positives = 161/482 (33%), Gaps = 65/482 (13%)
Query: 325 CLNCQHNTEGINCNKCR-PTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
CLN +G+ +C P Y GK L C P + G C ++ +C
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYT--GKNCQTL--VNLCSRSPCKNKGTCVQKKAESQC-- 1087
Query: 384 EFQPPDCSSCAYGYFDYPNCK-PCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG 442
P S A Y D PN + G EH G+C N C + G
Sbjct: 1088 -LCP---SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Query: 443 YYSPE-CKNCECNTVGSVSYVCDKLTG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCD 500
Y E C N + D + G C C Y G C Y C+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE------YEVDECQNQPCQ 1197
Query: 501 TSGTEPSICDDVSG--QCICKAGFGGPRCDQ----------CLSGYYM--QVLGRERQCV 546
GT C D+ +C C G G C++ CL+G ++ G +C+
Sbjct: 1198 NGGT----CIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCL 1253
Query: 547 P------CNCDPTGSTSTSCSADGKCNC--LTNFGGAQCDQCSPGYY--KYPD-CLSCNC 595
P C D S CS++G +C LTN C G + + D C C
Sbjct: 1254 PGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPC 1313
Query: 596 DVSGS--IGSTCDDNGLCHCKSNFDGAKC-DTCRE-QFYNYPACEECNCDPRGVTASFAG 651
G+ + S D +C C F GA+C +C + + C PR S
Sbjct: 1314 LNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRD 1373
Query: 652 CGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNT- 709
C S A CQ G C+ +P Y++ Q PF +C A C +
Sbjct: 1374 CESGCASSPCQ-----HGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 710 ----KSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
K+ VC + C Q G L + + I+N CD+
Sbjct: 1429 YCADKARDGVCDEACNSHAC-QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV 1487
Query: 766 HC 767
C
Sbjct: 1488 EC 1489
Score = 64.5 bits (150), Expect = 7e-09
Identities = 112/468 (23%), Positives = 162/468 (34%), Gaps = 84/468 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSS--------CAYGY------FDYPNCKPC 406
C C P F +CE E C+ P C C G+ D +C
Sbjct: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 407 TCNLNGTEG-EHCTPTDGLCPCKYNYAGKSCE----ICE-DGYYSPECKN------CECN 454
C LNG + +H P C C + G CE C+ D + +C++ C CN
Sbjct: 540 PC-LNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN 596
Query: 455 TVGSVSYVCDKLTGDC---------TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE 505
G + +C +C C +G CN CQ G C+ N D +
Sbjct: 597 P-GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN-CQPGTSGV-NCE-INFDDCASN 652
Query: 506 P---SICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTG 554
P IC D + C+C GF G RC+ + + C+ C C P G
Sbjct: 653 PCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCIC-PEG 711
Query: 555 STSTSC-SADGKC--------NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC 605
SC S +C NC G +C C G+ ++C D + + + C
Sbjct: 712 PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC-LCDAGWVG----INCEVDKNECLSNPC 766
Query: 606 DDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQ 662
+ G C N G +C TC++ F Y +EC +P + C +G C
Sbjct: 767 QNGGTCDNLVN--GYRC-TCKKGFKGYNCQVNIDECASNP---CLNQGTCFDDISGYTCH 820
Query: 663 CKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG----ACNTKSGQCVCK 717
C G+ C P N E E N L + G C +C+ K
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 718 QHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
+ C G Y + F +C+ DI + N C + G C
Sbjct: 881 PCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPC-QNGGSC 926
Score = 62.9 bits (146), Expect = 2e-08
Identities = 96/400 (24%), Positives = 132/400 (33%), Gaps = 78/400 (19%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
P C GY N C NGT G C C + G+ C+ +
Sbjct: 22 PAHALQCRDGYEPCVNEGMCVTYHNGT---------GYCKCPEGFLGEYCQ------HRD 66
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC----NCDTS 502
C+ C G+ V + G TC+ SG T CQ Y T PC C
Sbjct: 67 PCEKNRCQNGGTC--VAQAMLGKATCRCA-SGFTGEDCQ-----YSTSHPCFVSRPCLNG 118
Query: 503 GTEPSICDDVSGQCICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
GT + D +C C+ GF G C D CLS PC GST T+
Sbjct: 119 GTCHMLSRDTY-ECTCQVGFTGKECQWTDACLSH-------------PC---ANGSTCTT 161
Query: 560 CSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC---DDNGLCHCKSN 616
+ C CLT F G +C+ D C+ G TC + C C
Sbjct: 162 VANQFSCKCLTGFTGQKCE---------TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 617 FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCK 676
F G CD+ P C G +F C +P E C+ + + C+
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTG-DFTFE-CNCLPGFEGSTCERNIDDCPNHRCQ 270
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ 736
+ N + C +C G C +C+ Q + C +G
Sbjct: 271 NGGVCVDGVNTYNC-RCPPQWTGQF-----CTEDVDECLL-------QPNACQNGGTCAN 317
Query: 737 TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
N +GC C + G ++C + C S G C
Sbjct: 318 RNGGYGCV-C---VNGWSGDDCSENIDDCAFASCTPGSTC 353
Score = 62.1 bits (144), Expect = 4e-08
Identities = 90/342 (26%), Positives = 125/342 (36%), Gaps = 64/342 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC G +C+ G+ GF C + D+C N CLN C D+ G
Sbjct: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGF-KGYNCQVNIDECASNP--CLNQGTCFDDISG 816
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C C+ Y G ++C P P P N A+ C S N +C C PG+ G
Sbjct: 817 YTCH-CVLPYTG-------KNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQG 867
Query: 1850 ARC----EYCAAG---YYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--- 1899
RC + C + +G+ +T G Y C C + D C+ DCL
Sbjct: 868 QRCTIDIDECISKPCMNHGLCHNTQ---GSYM--CECPPGFSGMD---CEEDIDDCLANP 919
Query: 1900 -----KCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGTCVCRPG 1952
C++ +C LC PGF GD + C + C G + TC C+ G
Sbjct: 920 CQNGGSCMDGVNTFSC-LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAA 2011
G C+ +N CT +C + T D N C C G TG C
Sbjct: 979 FDGVHCEN------NINE---CTESSC--FNGGTCVDGINSFSCLCPVGFTGSFC----- 1022
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+ + H N G V + T +C C G G+ C
Sbjct: 1023 --LHEINECSSHPCLNEGTCVDGL--GTYRCSCPLGYTGKNC 1060
Score = 61.7 bits (143), Expect = 5e-08
Identities = 99/429 (23%), Positives = 150/429 (34%), Gaps = 74/429 (17%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYAGKSC 436
C C ++ DC+ D C N G+ C TDG C C YAG C
Sbjct: 401 CTCPQGYKGADCTE------DVDECAMANSNPCEHAGK-CVNTDGAFHCECLKGYAGPRC 453
Query: 437 EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
E+ + +S C+N D TC K G TC C G+
Sbjct: 454 EMDINECHSDPCQN------------------DATCLDKIGGFTC-LCMPGFKGV----H 490
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C + + + + C + +GQC+ K C +G Q+ + PC G+
Sbjct: 491 CELEINECQSNPCVN-NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC---LNGAK 546
Query: 557 STSCSADGKCNCLTNFGGAQC----DQCSPGYYKYPDC------LSCNCDVSGSIGSTCD 606
+C C T F G C D C P + C +C C+ G +G+ C
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN-PGYMGAICS 605
Query: 607 DN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTA--SFAGCGSVPAGELC 661
D C+ + +C + +CNC P GV +F C S P
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGY-------QCNCQPGTSGVNCEINFDDCASNPCIHGI 658
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG-QCVCKQHV 720
C D + C C P + Q N ++C N N +G +C+C +
Sbjct: 659 -CMDGINRYSC-VCSPGFTG-QRCN-IDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
Query: 721 GERQC----DQCLDG--FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
C ++CL + T + G +C CD G + NC+ +C + G
Sbjct: 713 HHPSCYSQVNECLSNPCIHGNCTGGLSG-YKCLCD-AGWVGINCEVDKNECLSNPCQNGG 770
Query: 775 RCDQPIRAH 783
CD + +
Sbjct: 771 TCDNLVNGY 779
Score = 61.3 bits (142), Expect = 6e-08
Identities = 86/344 (25%), Positives = 114/344 (33%), Gaps = 42/344 (12%)
Query: 1733 VEECQC-PRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
+ ECQ P G ++ P GF P C D C CLN C D+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPV-CQIDIDDCSSTP--CLNGAKCIDHP 551
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C +G+ G +C P P ++ + +C C PGY
Sbjct: 552 NGYECQ-CATGFTGVLCEENIDNC------DPDPCHHGQCQDGIDS----YTCICNPGYM 600
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK--PCNC----SG---NINPQDPGSCDSINGDCL 1899
GA C Y P D D CNC SG IN D S I+G C+
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TCVCRPGVIGE 1956
+N + C +C+PGF G I C + C + G + G C+C G
Sbjct: 661 DGINRYS---C-VCSPGFTGQRCNIDIDECASNPCRK-GATCINGVNGFRCICPEGPHHP 715
Query: 1957 KC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
C + C + H GL C C C+ D +C G CD
Sbjct: 716 SCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL 775
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G+ K G NC Q C + G C
Sbjct: 776 VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
Score = 60.1 bits (139), Expect = 1e-07
Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 46/304 (15%)
Query: 1784 CADNTI-GDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C N + G + C GY G D T D CA P + A C ++ +G+ C
Sbjct: 390 CDTNPLNGQYICTCPQGYKGADCT----EDVDECAMANSNPCEH-AGKC-VNTDGAF-HC 442
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGD-------YCKP----CNCSGNINPQDPGS 1890
C GY G RCE + P D D C P +C IN
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TC 1947
C + NG C+ VN C LC PGF G I +C++ C G D G C
Sbjct: 503 CVN-NGQCVDKVNRFQ---C-LCPPGFTGPVCQIDIDDCSSTPCLN-GAKCIDHPNGYEC 556
Query: 1948 VCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C G G C D C PD H G+ C C C D +C +
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYS--------VGFMCNATGQ--CECLPGVIG 2050
+ +C G+ + G NC + G + + C C PG G
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 2051 EKCD 2054
++C+
Sbjct: 677 QRCN 680
Score = 57.2 bits (132), Expect = 1e-06
Identities = 87/351 (24%), Positives = 120/351 (34%), Gaps = 57/351 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC C + G C Q + P C + C TG + + + C+
Sbjct: 130 ECTCQVGFTGKEC-QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE-CD 187
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPS---NNFALSCDLSE--NGSL--------ISC 1841
HG + P C CP + ++ + C S NG C
Sbjct: 188 IPGHCQHGGTCLNLPGSYQ-CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 1842 NCQPGYGGARCE---------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
NC PG+ G+ CE C G G+ D ++T + P +G +D C
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNG--GVCVD-GVNTYNCRCPPQWTGQFCTEDVDECL 303
Query: 1893 SINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C C N G C +C G+ GD +C+ I D+ A C + TC+
Sbjct: 304 LQPNACQNGGTCANRNGGYGC-VCVNGWSGD-----DCSENI-DDCAFASC-TPGSTCID 355
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRCAKGVTGKQ 2005
R V C C GL L C + CD + NGQ C C +G G
Sbjct: 356 R--VASFSC-MCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGAD 411
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATG--QCECLPGVIGEKCD 2054
C + D C N N G N G CECL G G +C+
Sbjct: 412 CTE--------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
Score = 56.8 bits (131), Expect = 1e-06
Identities = 92/387 (23%), Positives = 131/387 (33%), Gaps = 62/387 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + Y G CE + C C + D G C G HCE
Sbjct: 442 CECLKGYAGPRCE--------MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
Query: 1796 CMSGYHGDATVGTPR-----DCLICACPMPYPSNNFALSC-DLSENGSLISCNCQPGYGG 1849
++ + V + + C CP + + D S L C G
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG 553
Query: 1850 ARCEYCAAGYYGI--PEDTDLHTGDYCKPCNCSGNINPQ----DPGSCDSINGD------ 1897
C+ CA G+ G+ E+ D D C C I+ +PG +I D
Sbjct: 554 YECQ-CATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 1898 ---CL---KCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
CL +C++ G CN C PG G I +C + C G+ +CVC
Sbjct: 613 SSPCLNDGRCIDLVNGYQCN-CQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVC 670
Query: 1950 RPGVIGEKC----DRCA--PDHWGLN--TGLGCTPCNCGIASESTQCDDDNGQC------ 1995
PG G++C D CA P G G+ C C C +C
Sbjct: 671 SPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 1996 --RCAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVI 2049
C G++G +C C AG+ K+ C C G + + N +C C G
Sbjct: 731 HGNCTGGLSGYKC-LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY-RCTCKKGFK 788
Query: 2050 GEKCDRCPERWVLIPQEGCLECDSCTD 2076
G C + P CL +C D
Sbjct: 789 GYNCQVNIDECASNP---CLNQGTCFD 812
Score = 52.4 bits (120), Expect = 3e-05
Identities = 93/374 (24%), Positives = 125/374 (33%), Gaps = 67/374 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G C ++ + PC +G D+ G NC T G +CE
Sbjct: 593 CICNPGYMGAICSD------QIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVNCEI 644
Query: 1796 ----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C S HG G R +C+ N + + + N C G G
Sbjct: 645 NFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID-ECASNPCRKGATCINGVNG 703
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPC---NCSGNINPQ----DPG----SCDSINGDC 1898
RC C G + P PC NC+G ++ D G +C+ +C
Sbjct: 704 FRC-ICPEGPHH-PSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
Query: 1899 LK--------CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
L C N G C C GF G NC I DE C GTC
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCT-CKKGFKG-----YNCQVNI-DECASNPC-LNQGTCF-- 811
Query: 1951 PGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----DNGQCRCAKGVTGKQC 2006
+ G C C + G N PC+ + C + ++ C CA G G++C
Sbjct: 812 DDISGYTC-HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Query: 2007 DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCDRCPERWVLIP 2064
T D D C + G N G CEC PG G C+ + + P
Sbjct: 871 ----------TID-IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 2065 QEGCLECDSCTDAL 2078
C SC D +
Sbjct: 920 ---CQNGGSCMDGV 930
Score = 48.0 bits (109), Expect = 6e-04
Identities = 73/295 (24%), Positives = 108/295 (36%), Gaps = 67/295 (22%)
Query: 1766 QCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNN 1825
QC + C VN G+C+ + T +C+ C G+ G+ C P N
Sbjct: 27 QCRDGYEPC-VNEGMCVTYHNGT--GYCK-CPEGFLGE----------YCQHRDPCEKNR 72
Query: 1826 FALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC---KPCNCSGN 1882
C +NG +C Q G A C CA+G+ G ED T C +PC
Sbjct: 73 ----C---QNGG--TCVAQAMLGKATCR-CASGFTG--EDCQYSTSHPCFVSRPC----- 115
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTACICDEFGMADCD 1941
+ G+C ++ D +C C GF G + ++ C + C
Sbjct: 116 ---LNGGTCHMLSRDTYECT----------CQVGFTGKECQWTDACLSHPCANGSTCTTV 162
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKG 2000
+ +C C G G+KC+ + C P +C QC+C +G
Sbjct: 163 ANQFSCKCLTGFTGQKCETDVNE---------CDIPGHCQHGGTCLNLPGSY-QCQCPQG 212
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
TG+ CD Y C C G + + T +C CLPG G C+R
Sbjct: 213 FTGQYCDSL------YVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 27/149 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNC--RPCHCPSTAICDDNGM-CICPKNVEGENC-DRC 1414
C C P G+ C+ C PC +T I NG CICP+ +C +
Sbjct: 668 CVCSPGFTGQRCNI------DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Query: 1415 KPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
N + C C C+ G VG + CE D +C G CD+ V G
Sbjct: 722 NECLSNPCIHGNCTGGLSGYKCLCDA-GWVG--INCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Y+CTC + Y+ C N +C
Sbjct: 779 -------YRCTCKKGFKGYN-CQVNIDEC 799
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/181 (25%), Positives = 62/181 (34%), Gaps = 22/181 (12%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCR--PCHCP 1389
C C +G T C +C P G TCS C GY G NC C
Sbjct: 1135 CQCP-LGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGV-NCEYEVDECQ 1192
Query: 1390 STAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG 1449
+ C + G CI V C C P T + DDC P + G Q
Sbjct: 1193 NQP-CQNGGTCI--DLVNHFKCS-CPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C C G C+ + +C C+ G+ + N C C++ G+ C+
Sbjct: 1249 SCRCLPGFAGERCEGDI------NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Query: 1510 T 1510
T
Sbjct: 1303 T 1303
Score = 44.0 bits (99), Expect = 0.010
Identities = 47/191 (24%), Positives = 69/191 (36%), Gaps = 16/191 (8%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPC--HCPSTAICDDNGMCICPKNVEGENCDRCKP 1416
C PN TC C G+ G C C S C ++G+C N +G C P
Sbjct: 848 CKESPNFESYTC-LCAPGWQG-QRCTIDIDECISKP-CMNHGLC---HNTQGSYMCECPP 901
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
D + DDC NP G+ + ++ C C G C + + P
Sbjct: 902 GFSGMDCEEDIDDCLANPCQNGGSCMD-GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
Query: 1477 QCTCNRHGTTYDV-CDQNTAQCYCKTNVR---GQAC---DTCKEEYFNLQDDNPDGCTKC 1529
TC+ + +Y C +C+ N+ +C TC + + P G T
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS 1020
Query: 1530 FCFGKTTRCSS 1540
FC + CSS
Sbjct: 1021 FCLHEINECSS 1031
Score = 41.5 bits (93), Expect = 0.056
Identities = 51/184 (27%), Positives = 66/184 (35%), Gaps = 26/184 (14%)
Query: 1336 GARPCLC--DFMG-STELECNTFGGQCPCKPN-----VIGRTCSACRTGYYGFPNCRPC- 1386
G CLC F G ELE N PC N + R C G+ G P C+
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQCVDKVNRFQCLCPPGFTG-PVCQIDI 533
Query: 1387 -HCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C ST C + CI N G C +T + D+C+ +P Q Q
Sbjct: 534 DDCSSTP-CLNGAKCIDHPN--GYECQCATGFT-GVLCEENIDNCDPDPCH--HGQCQDG 587
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRG 1505
DS C C G +C + +CY C G D+ N QC C+ G
Sbjct: 588 IDSYTCICNPGYMGAICSDQI------DECYSSPCLNDGRCIDLV--NGYQCNCQPGTSG 639
Query: 1506 QACD 1509
C+
Sbjct: 640 VNCE 643
Score = 40.7 bits (91), Expect = 0.097
Identities = 58/228 (25%), Positives = 75/228 (32%), Gaps = 28/228 (12%)
Query: 1757 LPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICA 1816
+P GF C +C + G + C G+ C SG +PRDC
Sbjct: 1325 MPDGFICRCPPGFSGARCQSSCGQ-VKCRK---GEQCVHTASGPR--CFCPSPRDCESGC 1378
Query: 1817 CPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP 1876
P SC SC C P + G+RCE A P T L YC
Sbjct: 1379 ASSPCQHGG---SCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCL--SQYCAD 1432
Query: 1877 CNCSGNINPQ-DPGSCDSINGDC-LKCVNNTAGAACNL-CAPGFYGDAIFSKNCTACICD 1933
G + + +C GDC L N A + L C N C+ D
Sbjct: 1433 KARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFD 1492
Query: 1934 EFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLN-TGLGCTPCNCG 1980
F +C + TC K D+ DH+ N GC CG
Sbjct: 1493 NF---ECQGNSKTC---------KYDKYCADHFKDNHCNQGCNSEECG 1528
Score = 39.1 bits (87), Expect = 0.30
Identities = 45/212 (21%), Positives = 73/212 (34%), Gaps = 14/212 (6%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYP-----NCKPCTCNLNGTEG 415
C+C P FS C+ G+ +CR Q +S + P C C G+
Sbjct: 1331 CRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
Query: 416 EHCTPTDGLCPCKYNYAGKSCEICEDGYYSP--ECKNCECNTVGSVSYVCDKLTGDCTCK 473
P C C ++G CE+ +P C + C VCD+ C
Sbjct: 1391 PQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKAR-DGVCDEACNSHAC- 1448
Query: 474 SKYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLS 532
++ G C+ + + N + PC + +C+ V +C+ C
Sbjct: 1449 -QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV--ECLFDNFECQGNSKTCKY 1505
Query: 533 GYYMQVLGRERQC-VPCNCDPTGSTSTSCSAD 563
Y ++ C CN + G C+AD
Sbjct: 1506 DKYCADHFKDNHCNQGCNSEECGWDGLDCAAD 1537
Score = 35.5 bits (78), Expect = 3.6
Identities = 51/216 (23%), Positives = 74/216 (34%), Gaps = 30/216 (13%)
Query: 1301 REFIEQCASYNYYIS-PNETGLCREAMFSITSEYNSGARPC---LCDFMGSTELECNTFG 1356
R+ E C + ++ N TG C+ EY PC C G+ +
Sbjct: 29 RDGYEPCVNEGMCVTYHNGTGYCK-CPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 87
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA--ICDDNGMCICPKNVEGENCDRC 1414
C C G C T + F + RPC T + D C C G+ C
Sbjct: 88 ATCRCASGFTGEDCQYS-TSHPCFVS-RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-- 143
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD 1474
+T + + C N + V NQ C+ +G + CD +PGH
Sbjct: 144 --WT-DACLSHPC--ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD--IPGH----- 191
Query: 1475 CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C GT ++ + QC C GQ CD+
Sbjct: 192 -----CQHGGTCLNL--PGSYQCQCPQGFTGQYCDS 220
Score = 35.1 bits (77), Expect = 4.8
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 21/226 (9%)
Query: 1340 CLCDFMGSTELECNTFGGQCPCKPNVIGRTCS--------ACRTGYYGFPNCRPCHCPST 1391
CLC G T +C T +C +P G TCS C+ G+ G + +
Sbjct: 935 CLC-LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
Query: 1392 AICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSG-- 1449
+ C + G C+ + +C +T +F + ++C+ +P N+ C G
Sbjct: 994 SSCFNGGTCV--DGINSFSCLCPVGFTGSFCLHE-INECSSHP---CLNEGTCVDGLGTY 1047
Query: 1450 KCACRENVRGRVCDHCVPGHYAFPDCYQCTC-NRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
+C+C G+ C V P + TC + + +C A YC +V +C
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC--DVPNVSC 1105
Query: 1509 DTCKEEYFNLQDDNPDGCTKCFCFGKTTRCSSSY-YTWAAIDEMVD 1553
D L + C G T C YT + +E +D
Sbjct: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 78.2 bits (184), Expect = 5e-13
Identities = 92/356 (25%), Positives = 131/356 (36%), Gaps = 69/356 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C DG+ ECK C ++ + + G+C C + GR C++C YP C +
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDEC----VPYPGCVHGS 286
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C EP QC C+ +GG CD+ L+ G C G T
Sbjct: 287 C----VEP-------WQCNCETNWGGLLCDKDLN-----YCGSHHPCT------NGGTCI 324
Query: 559 SCSADG-KCNCLTNFGGAQCDQ---------CSPG--YYKYPDCLSCNCDVSGSIGSTCD 606
+ D +C C + G C++ C+ G ++ P C+C SG G TC
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP-SGWSGPTCA 383
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTAS----FAGCGSVPAGELCQ 662
+ + C SN A TC +Q + EC C + V A+ C P
Sbjct: 384 LD-IDECASN-PCAAGGTCVDQVDGF----ECICPEQWVGATCQLDVNDCEGKPCLNAFS 437
Query: 663 CKDRVQGRICNDCKPLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVG 721
CK+ + G C DC P + + N C + C GT L QCVC + G
Sbjct: 438 CKNLIGGYYC-DCIPGWKGINCHINVNDC-RGQCQHGGTCKDL----VNGYQCVCPRGFG 491
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R C+ D C C GG ++ D CHC G C+
Sbjct: 492 GRHCELERD-----------KCASSPCHSGGLCEDLADGF--HCHCPQGFSGPLCE 534
Score = 72.9 bits (171), Expect = 2e-11
Identities = 138/550 (25%), Positives = 191/550 (34%), Gaps = 101/550 (18%)
Query: 255 RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLD 314
RC N CNK C + + D++ + C EC + ++ +L
Sbjct: 197 RCDENYYSATCNKFCR--PRNDFFGHYTCDQYGNKACMDGWMGKECK--EAVCKQGCNL- 251
Query: 315 INGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEE 374
++G G+C C + +G C++C P +G +P QC NCE
Sbjct: 252 LHGGCTVPGEC-RCSYGWQGRFCDECVPYPGCVHGS------CVEPWQC-------NCET 297
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGK 434
G C D + C + PCT NG + P C C Y+G+
Sbjct: 298 NWGGLLC-----DKDLNYCGSHH-------PCT---NGGTCINAEPDQYRCTCPDGYSGR 342
Query: 435 SCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT 493
+CE E S C N C+ V S +C C S +SG TC +
Sbjct: 343 NCEKAEHACTSNPCANGGSCHEVPS--------GFECHCPSGWSGPTC------ALDIDE 388
Query: 494 CKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCD---------QCLSGYYMQVL--GR 541
C C GT D V G +CIC + G C CL+ + + L G
Sbjct: 389 CASNPCAAGGT---CVDQVDGFECICPEQWVGATCQLDVNDCEGKPCLNAFSCKNLIGGY 445
Query: 542 ERQCVP----CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY------YKYPDC 590
C+P NC C G C L N G QC C G+ + C
Sbjct: 446 YCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVN--GYQC-VCPRGFGGRHCELERDKC 502
Query: 591 LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA 650
S C SG + D CHC F G C+ + CE C + A
Sbjct: 503 ASSPCH-SGGLCEDLADGFHCHCPQGFSGPLCEV------DVDLCEPSPC------RNGA 549
Query: 651 GCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGC-EQCNCNLAGTLNSLGACN 708
C ++ C C D G+ C+ +P GC + GT S G C
Sbjct: 550 RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVID-GCGSDAGPGMPGTAAS-GVCG 607
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G+CV Q G C C GF ++ + C C GG+ + D +C C
Sbjct: 608 -PHGRCV-SQPGGNFSC-ICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD--AFRCFC 662
Query: 768 HSRVEGRRCD 777
S EG CD
Sbjct: 663 PSGWEGELCD 672
Score = 67.3 bits (157), Expect = 1e-09
Identities = 113/461 (24%), Positives = 159/461 (34%), Gaps = 89/461 (19%)
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
D G+ + GG C + G C C R +G R EL+ C P S G CE
Sbjct: 464 DCRGQCQHGGTCKDL---VNGYQC-VCP----RGFGGRHCELER-DKCASSPCHSGGLCE 514
Query: 374 E--ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDG--LCPCKY 429
+ + C C F P C D C+P C G C +G C C
Sbjct: 515 DLADGFHCHCPQGFSGPLCE------VDVDLCEPSPCR----NGARCYNLEGDYYCACPD 564
Query: 430 NYAGKSCEICEDGYYSPECKNCE-CNTVGSVSYVCDKLTGDC----TCKSKYSGRTCNQC 484
++ GK+C + + C+ + C + +G C C S+ G C
Sbjct: 565 DFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC 624
Query: 485 QAGYY------NYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQ 537
+G+ N C C GT D+V +C C +G+ G CD
Sbjct: 625 DSGFTGTYCHENIDDCLGQPCRNGGT---CIDEVDAFRCFCPSGWEGELCDT-------- 673
Query: 538 VLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDV 597
C+P DP C + G+C L N CD G + C+
Sbjct: 674 ---NPNDCLP---DP-------CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA-Y 719
Query: 598 SGSIGSTCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ S G TC D+G C C + G+ C + +C C G C
Sbjct: 720 TCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS-----SCLPNPCVNGGT------CVG 768
Query: 655 VPAGELCQCKDRVQGRIC----NDCKPL-YWN----LQEYNPFGCEQCNCNLAGTLNSLG 705
A C C+D +GR C NDC PL +N + N F CE C AG +
Sbjct: 769 SGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRIN 827
Query: 706 ACNTKSGQC----VCKQHVGERQCDQCLDGFYRLQTNDVFG 742
+S C C + +C C G + +V G
Sbjct: 828 IDECQSSPCAYGATCVDEINGYRC-SCPPGRAGPRCQEVIG 867
Score = 66.9 bits (156), Expect = 1e-09
Identities = 92/336 (27%), Positives = 125/336 (37%), Gaps = 62/336 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCV-PCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
EC+C ++G C++C + G CV P QCN C+ N G L D N G H
Sbjct: 261 ECRCSYGWQGRFCDECVP-YPGCVHGSCVEPWQCN-----CETNWGGLLCDKDLNYCGSH 314
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C +G + D C CP Y N C+ +E+ +C P G C
Sbjct: 315 -HPCT---NGGTCINAEPDQYRCTCPDGYSGRN----CEKAEH----ACTSNPCANGGSC 362
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ +P + H C P SG D C S C AG C
Sbjct: 363 -------HEVPSGFECH----C-PSGWSGPTCALDIDECAS--NPC------AAGGTCVD 402
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDS--TTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
GF + I + C + + DC+ C+ + G CD C P G+N
Sbjct: 403 QVDGF--ECICPEQWVGATC-QLDVNDCEGKPCLNAFSCKNLIGGYYCD-CIPGWKGINC 458
Query: 1971 GLGCTPCNCGIASESTQCDD-DNG-QCRCAKGVTGKQC----DQCAA------GFWNYTK 2018
+ C G C D NG QC C +G G+ C D+CA+ G
Sbjct: 459 HINVNDCR-GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLA 517
Query: 2019 DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKC 2053
DG HC+C G+S G +C CE P G +C
Sbjct: 518 DGF-HCHCPQGFS-GPLCEVDVDLCEPSPCRNGARC 551
Score = 62.9 bits (146), Expect = 2e-08
Identities = 136/568 (23%), Positives = 195/568 (34%), Gaps = 127/568 (22%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
CRC + G C++C + W CNC + D +++
Sbjct: 262 CRCSYGWQGRFCDECVPYPGCVHGSCVEPWQ------CNCETNWGGLLCDKDLN----YC 311
Query: 314 DINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE 373
+ GG C+N + + C P Y G+ ++ + C +P + G+C
Sbjct: 312 GSHHPCTNGGTCINAEPDQYRCTC----PDGYS--GRNCEKAE--HACTSNPCANGGSCH 363
Query: 374 E-ESG-RCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCT-PTDGL-CPCKY 429
E SG C C + P C+ D C C GT C DG C C
Sbjct: 364 EVPSGFECHCPSGWSGPTCA------LDIDECASNPCAAGGT----CVDQVDGFECICPE 413
Query: 430 NYAGKSCEICEDGYYSPECKNC-EC-NTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAG 487
+ G +C++ + C N C N +G Y CD + G + G C
Sbjct: 414 QWVGATCQLDVNDCEGKPCLNAFSCKNLIG--GYYCDCIPG-------WKGINC------ 458
Query: 488 YYNYPTCKPCNCDTSGTEPSICDD-VSG-QCICKAGFGGPRCDQCLSGYYMQVLGRERQC 545
+ N C+ C GT C D V+G QC+C GFGG C+ L R++ C
Sbjct: 459 HINVNDCRG-QCQHGGT----CKDLVNGYQCVCPRGFGGRHCE----------LERDK-C 502
Query: 546 VPCNCDPTGSTSTSCSADG-KCNCLTNFGGAQC----DQCSPGYYKYPDCLSCNCDVSGS 600
C G ADG C+C F G C D C P C +G+
Sbjct: 503 ASSPCHSGGLCED--LADGFHCHCPQGFSGPLCEVDVDLCEPS--------PCR---NGA 549
Query: 601 IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC---EECNCD---------PRGVTAS 648
+ + C C +F G C RE AC + C D GV
Sbjct: 550 RCYNLEGDYYCACPDDFGGKNCSVPREPCPG-GACRVIDGCGSDAGPGMPGTAASGVCGP 608
Query: 649 FAGCGSVPAGEL-CQCKDRVQGRICND---------CKPLYWNLQEYNPFGCEQCNCNLA 698
C S P G C C G C++ C+ + E + F C C
Sbjct: 609 HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRC-FCPSGWE 667
Query: 699 GTLNSLGACNTKSGQCV---------CKQHVGERQCDQCLDGFY-RLQTNDVFGCTECDC 748
G L C+T C+ C V + C C DG+ + + F C C
Sbjct: 668 GEL-----CDTNPNDCLPDPCHSRGRCYDLVNDFYC-ACDDGWKGKTCHSREFQCDAYTC 721
Query: 749 DIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
GG+ ++ D T +C C +G C
Sbjct: 722 SNGGTCYDSGD--TFRCACPPGWKGSTC 747
Score = 60.1 bits (139), Expect = 1e-07
Identities = 99/375 (26%), Positives = 128/375 (34%), Gaps = 67/375 (17%)
Query: 1734 EECQCPRAYRGLSCEQCAEG-HYRLPSGFCVPCQCNGHSDQCDVNTGICLNCAD--NTIG 1790
++C + G CE A+G H P GF P C D C+ + C N A N G
Sbjct: 500 DKCASSPCHSGGLCEDLADGFHCHCPQGFSGPL-CEVDVDLCEPSP--CRNGARCYNLEG 556
Query: 1791 DHCEFCMSGYHGDATVGTPRD-CLICACPM----------PYPSNNFALSCD-----LSE 1834
D+ C + G PR+ C AC + P + C +S+
Sbjct: 557 DYYCACPDDF-GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGD----YCKPCNCSGNI---N 1884
G SC C G+ G C G P T + D +C P G + N
Sbjct: 616 PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTN 674
Query: 1885 PQD--PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADC 1940
P D P C S G C VN+ A C G+ G S+ C A C G
Sbjct: 675 PNDCLPDPCHS-RGRCYDLVNDFYCA----CDDGWKGKTCHSREFQCDAYTCSNGGTCYD 729
Query: 1941 DSTTGTCVCRPGVIGEKC-----DRCAPD---HWGLNTGLGCT-PCNCGIASESTQCDDD 1991
T C C PG G C C P+ + G G G + C C E C +
Sbjct: 730 SGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN 789
Query: 1992 NGQCR---------CAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNA 2038
C C GV +C+ CA GF D C C G + N
Sbjct: 790 TNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEING 848
Query: 2039 TGQCECLPGVIGEKC 2053
+C C PG G +C
Sbjct: 849 Y-RCSCPPGRAGPRC 862
Score = 49.2 bits (112), Expect = 3e-04
Identities = 64/242 (26%), Positives = 88/242 (36%), Gaps = 45/242 (18%)
Query: 1784 CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C D C FC SG+ G+ P DCL P P ++ DL + C C
Sbjct: 651 CIDEVDAFRC-FCPSGWEGELCDTNPNDCL------PDPCHSRGRCYDLVND---FYCAC 700
Query: 1844 QPGYGGARC---EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI--NGDC 1898
G+ G C E+ Y T +GD + C C P GS ++ N C
Sbjct: 701 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR-CACP----PGWKGSTCAVAKNSSC 755
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTC---------V 1948
L N C G G + S +CIC D + C T C +
Sbjct: 756 LP----------NPCVNG--GTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 803
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC-DDDNG-QCRCAKGVTGKQC 2006
C GV +C+ CAP G + + C + C D+ NG +C C G G +C
Sbjct: 804 CVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 862
Query: 2007 DQ 2008
+
Sbjct: 863 QE 864
Score = 43.2 bits (97), Expect = 0.018
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 34/193 (17%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC--SACRTGYYG 1379
C E +S T N RP DF G C+ +G + C +G+ C + C+ G
Sbjct: 198 CDENYYSATC--NKFCRP-RNDFFG--HYTCDQYGNKA-CMDGWMGKECKEAVCKQG--- 248
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
C H C G C C +G CD C PY GC +C V
Sbjct: 249 ---CNLLH----GGCTVPGECRCSYGWQGRFCDECVPYP-------GCVHGSC----VEP 290
Query: 1440 NQLQCEADSGKCACRENVRGRVCDH-CVPGH---YAFPDCYQCTCNRHGTTYDVCDQNTA 1495
Q CE + G C +++ H C G A PD Y+CTC G + C++
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEH 349
Query: 1496 QCYCKTNVRGQAC 1508
C G +C
Sbjct: 350 ACTSNPCANGGSC 362
Score = 42.7 bits (96), Expect = 0.024
Identities = 43/158 (27%), Positives = 55/158 (34%), Gaps = 28/158 (17%)
Query: 1383 CRPCHCPSTAIC---DDNGMCICPKNVEGENC----DRCKPYTFNFDVQRGCDDCNCNP- 1434
C P C + A C + + C CP + G+NC + C G D P
Sbjct: 540 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPG 599
Query: 1435 ---LGVVGNQLQCEADSG---KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD 1488
GV G +C + G C C G C H DC C GT D
Sbjct: 600 TAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC------HENIDDCLGQPCRNGGTCID 653
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
D +C+C + G+ CDT N D PD C
Sbjct: 654 EVD--AFRCFCPSGWEGELCDT------NPNDCLPDPC 683
Score = 41.5 bits (93), Expect = 0.056
Identities = 95/350 (27%), Positives = 118/350 (33%), Gaps = 71/350 (20%)
Query: 1735 ECQCPRAYRGLSC---------EQCAEGHYRLPS--GF-CV-PCQCNGHSDQCDVNT--- 1778
EC CP + G +C CA G + GF C+ P Q G + Q DVN
Sbjct: 370 ECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCEG 429
Query: 1779 GICLNC--ADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENG 1836
CLN N IG + C+ G+ G DC C +C NG
Sbjct: 430 KPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCR-GQC-------QHGGTCKDLVNG 481
Query: 1837 SLISCNCQPGYGGARCEY----CAAG---YYGIPEDTDLHTGDYCK-PCNCSGNINPQDP 1888
C C G+GG CE CA+ G+ E DL G +C P SG + D
Sbjct: 482 --YQCVCPRGFGGRHCELERDKCASSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDV 537
Query: 1889 GSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTC 1947
C+ C N GA C +Y C C D+FG +C C
Sbjct: 538 DLCEP-----SPCRN---GARCYNLEGDYY-----------CACPDDFGGKNCSVPREPC 578
Query: 1948 VCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD 2007
PG D C D G + CG N C C G TG C
Sbjct: 579 ---PGGACRVIDGCGSDAGPGMPGTAASGV-CGPHGRCVSQPGGNFSCICDSGFTGTYCH 634
Query: 2008 QCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
+ D C C G + +A +C C G GE CD P
Sbjct: 635 E--------NIDDCLGQPCRNGGTCIDEVDAF-RCFCPSGWEGELCDTNP 675
Score = 38.3 bits (85), Expect = 0.52
Identities = 41/150 (27%), Positives = 48/150 (32%), Gaps = 14/150 (9%)
Query: 1920 DAIFSKNCTACICDE---FGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP 1976
D K C +C + C + G C C G G CD C P + G G P
Sbjct: 233 DGWMGKECKEAVCKQGCNLLHGGC-TVPGECRCSYGWQGRFCDECVP-YPGCVHGSCVEP 290
Query: 1977 --CNCGIASESTQCDDDNGQCRCAKGVT-GKQCDQCAAGFWNYT-KDGCDHCNCNTG--Y 2030
CNC CD D C T G C + T DG NC
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Query: 2031 SVGFMCNATGQCECLPGVIGEKCDRCPERW 2060
C G C +P G +C CP W
Sbjct: 351 CTSNPCANGGSCHEVPS--GFEC-HCPSGW 377
Score = 36.7 bits (81), Expect = 1.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 15/61 (24%)
Query: 1449 GKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+C C +GR CD CVP +P C HG+ + QC C+TN G C
Sbjct: 260 GECRCSYGWQGRFCDECVP----YPGCV------HGSCVE-----PWQCNCETNWGGLLC 304
Query: 1509 D 1509
D
Sbjct: 305 D 305
Score = 35.9 bits (79), Expect = 2.8
Identities = 39/153 (25%), Positives = 46/153 (30%), Gaps = 29/153 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG---MCICPKNVEGENCDRCK 1415
C C G+TC + C C + C D+G C CP +G C K
Sbjct: 698 CACDDGWKGKTCHSREF------QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 1416 PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDC 1475
C NP V G S C CR+ GR C H DC
Sbjct: 752 N-----------SSCLPNPC-VNGGTCVGSGASFSCICRDGWEGRTCTHNT------NDC 793
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C G D N +C C G C
Sbjct: 794 NPLPCYNGGICVD--GVNWFRCECAPGFAGPDC 824
Score = 34.7 bits (76), Expect = 6.4
Identities = 47/190 (24%), Positives = 73/190 (38%), Gaps = 38/190 (20%)
Query: 1340 CLC--DFMGST-ELECNTFGGQCPCK-----PNVIGRTCSACRTGYYGFP---NCRPCH- 1387
C+C ++G+T +L+ N G+ PC N+IG C G+ G N C
Sbjct: 409 CICPEQWVGATCQLDVNDCEGK-PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG 467
Query: 1388 -CPSTAICDD--NG-MCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ 1443
C C D NG C+CP+ G +C +++R D C +P G +
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHC----------ELER--DKCASSPCH-SGGLCE 514
Query: 1444 CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
AD C C + G +C+ V C C Y++ + C C +
Sbjct: 515 DLADGFHCHCPQGFSGPLCEVDV------DLCEPSPCRNGARCYNL--EGDYYCACPDDF 566
Query: 1504 RGQACDTCKE 1513
G+ C +E
Sbjct: 567 GGKNCSVPRE 576
>AY764260-1|AAW47407.1| 167|Homo sapiens netrin G1 isoform G1a
protein.
Length = 167
Score = 77.8 bits (183), Expect = 7e-13
Identities = 39/118 (33%), Positives = 53/118 (44%), Gaps = 7/118 (5%)
Query: 516 CI-CKAGFGGPRCDQCLSGYYMQV---LGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
C+ CK G C+ C GY+ L E C+ C C+P GS C+ G C C T
Sbjct: 40 CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTG 99
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCD---VSGSIGSTCDDNGLCHCKSNFDGAKCDTCR 626
G +CD+C PG + C CD + G TC +N C C + + G C+ R
Sbjct: 100 TTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR 157
Score = 74.1 bits (174), Expect = 9e-12
Identities = 46/150 (30%), Positives = 65/150 (43%), Gaps = 18/150 (12%)
Query: 291 CNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGK 350
C C H+ C+Y ID + C++C+HNT G +C CR Y+R
Sbjct: 20 CECFGHSNRCSY---IDLLNTVI-----------CVSCKHNTRGQHCELCRLGYFRNASA 65
Query: 351 RWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCN- 409
+ D+ +VC C C+P S + SG CEC+ P C C G + C+P C+
Sbjct: 66 QLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDN 125
Query: 410 --LNGTEGEHCTPTDGLCPCKYNYAGKSCE 437
L+ G C + C C Y G CE
Sbjct: 126 ELLHCQNGGTC-HNNVRCLCPAAYTGILCE 154
Score = 67.7 bits (158), Expect = 7e-10
Identities = 50/153 (32%), Positives = 69/153 (45%), Gaps = 26/153 (16%)
Query: 1765 CQCNGHSDQCD----VNTGICLNCADNTIGDHCEFCMSGY--HGDATVGTPRDCLICACP 1818
C+C GHS++C +NT IC++C NT G HCE C GY + A + C+ C C
Sbjct: 20 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC- 78
Query: 1819 MPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCN 1878
P + C NGS C C+ G G +C+ C G H G C+P
Sbjct: 79 --NPLGSIHDRC----NGSGF-CECKTGTTGPKCDECLPG-------NSWHYG--CQPNV 122
Query: 1879 CSGN-INPQDPGSCDSINGDCLKCVNNTAGAAC 1910
C ++ Q+ G+C + N CL C G C
Sbjct: 123 CDNELLHCQNGGTCHN-NVRCL-CPAAYTGILC 153
Score = 66.1 bits (154), Expect = 2e-09
Identities = 45/143 (31%), Positives = 66/143 (46%), Gaps = 18/143 (12%)
Query: 1877 CNCSGNINPQDPGSCDSINGD-CLKCVNNTAGAACNLCAPGFYGDA---IFSKN-CTACI 1931
C C G+ N D +N C+ C +NT G C LC G++ +A + +N C C
Sbjct: 20 CECFGHSNRCS--YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECY 77
Query: 1932 CDEFG-MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD 1990
C+ G + D + +G C C+ G G KCD C P G + GC P C +E C +
Sbjct: 78 CNPLGSIHDRCNGSGFCECKTGTTGPKCDECLP---GNSWHYGCQPNVCD--NELLHCQN 132
Query: 1991 -----DNGQCRCAKGVTGKQCDQ 2008
+N +C C TG C++
Sbjct: 133 GGTCHNNVRCLCPAAYTGILCEK 155
Score = 61.7 bits (143), Expect = 5e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 15/126 (11%)
Query: 1399 MCI-CPKNVEGENCDRCKPYTFN-----FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCA 1452
+C+ C N G++C+ C+ F D + C +C CNPLG + ++ C SG C
Sbjct: 39 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR--CNG-SGFCE 95
Query: 1453 CRENVRGRVCDHCVPGHYAFPDCYQCTCNR---HGTTYDVCDQNTAQCYCKTNVRGQACD 1509
C+ G CD C+PG+ C C+ H C N +C C G C+
Sbjct: 96 CKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTC-HNNVRCLCPAAYTGILCE 154
Query: 1510 --TCKE 1513
C+E
Sbjct: 155 KLRCEE 160
Score = 60.5 bits (140), Expect = 1e-07
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 14/115 (12%)
Query: 427 CKYNYAGKSCEICEDGYY---------SPECKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
CK+N G+ CE+C GY+ C C CN +GS+ C+ +G C CK+ +
Sbjct: 43 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTT 101
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTS---GTEPSICDDVSGQCICKAGFGGPRCDQ 529
G C++C G + C+P CD C + + +C+C A + G C++
Sbjct: 102 GPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHN-NVRCLCPAAYTGILCEK 155
Score = 58.8 bits (136), Expect = 3e-07
Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 26/164 (15%)
Query: 450 NCEC-NTVGSVSYVCDKLTGDC-TCKSKYSGRTCNQCQAGYYNYPT--------CKPCNC 499
NCEC SY+ T C +CK G+ C C+ GY+ + C C C
Sbjct: 19 NCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC 78
Query: 500 DTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
+ G+ C+ SG C CK G GP+CD+CL G C P CD +
Sbjct: 79 NPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHY-----GCQPNVCD---NELLH 129
Query: 560 CSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
C G C+ +C P Y C C+ +GS GS
Sbjct: 130 CQNGGTCH-----NNVRC--LCPAAYTGILCEKLRCEEAGSCGS 166
Score = 54.8 bits (126), Expect = 6e-06
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 567 NCLTNFGGAQCDQCSPGYYKYPD--------CLSCNCDVSGSIGSTCDDNGLCHCKSNFD 618
+C N G C+ C GY++ C+ C C+ GSI C+ +G C CK+
Sbjct: 42 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTT 101
Query: 619 GAKCDTCREQFYNYPACEECNCD 641
G KCD C + C+ CD
Sbjct: 102 GPKCDECLPGNSWHYGCQPNVCD 124
Score = 52.4 bits (120), Expect = 3e-05
Identities = 49/164 (29%), Positives = 64/164 (39%), Gaps = 34/164 (20%)
Query: 222 IKDISIGGRCMCNGHADTCEPADPAGNLNILVC-RCQHNTCGPQCNKCCSGFEQKKWRIS 280
I IS G C C GH++ C D LN ++C C+HNT G C C G+ + +
Sbjct: 11 IPSISSIGNCECFGHSNRCSYID---LLNTVICVSCKHNTRGQHCELCRLGYFRN--ASA 65
Query: 281 QNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKC 340
Q D C C C+ + I+ R G G C C+ T G C++C
Sbjct: 66 QLDDENVCIECYCNPLGS----------------IHDRCNGSGFC-ECKTGTTGPKCDEC 108
Query: 341 RPTYYRPYGKRWDELDVCQPCQCDP---HFSTGNCEEESGRCEC 381
P YG CQP CD H G + RC C
Sbjct: 109 LPGNSWHYG--------CQPNVCDNELLHCQNGGTCHNNVRCLC 144
Score = 51.2 bits (117), Expect = 7e-05
Identities = 33/119 (27%), Positives = 44/119 (36%), Gaps = 11/119 (9%)
Query: 1307 CASYNYYISPNETGLCREAMFSITSEYNSGARPCL---CDFMGSTELECNTFGGQCPCKP 1363
C S + LCR F S C+ C+ +GS CN G C CK
Sbjct: 40 CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKT 98
Query: 1364 NVIGRTCSACRTGYYGFPNCRP--C-----HCPSTAICDDNGMCICPKNVEGENCDRCK 1415
G C C G C+P C HC + C +N C+CP G C++ +
Sbjct: 99 GTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR 157
Score = 50.0 bits (114), Expect = 2e-04
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 1997 CAKGVTGKQCDQCAAGFWNYT------KDGCDHCNCNTGYSVGFMCNATGQCECLPGVIG 2050
C G+ C+ C G++ ++ C C CN S+ CN +G CEC G G
Sbjct: 43 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTG 102
Query: 2051 EKCDRC 2056
KCD C
Sbjct: 103 PKCDEC 108
Score = 47.2 bits (107), Expect = 0.001
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 17/128 (13%)
Query: 1944 TGTCV-CRPGVIGEKCDRCAPDHWG-----LNTGLGCTPCNCG-IASESTQCDDDNGQCR 1996
T CV C+ G+ C+ C ++ L+ C C C + S +C+ +G C
Sbjct: 37 TVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCE 95
Query: 1997 CAKGVTGKQCDQCAAG-FWNYTKDGCDHCNCNTGY---SVGFMCNATGQCECLPGVIGEK 2052
C G TG +CD+C G W+Y GC C+ G C+ +C C G
Sbjct: 96 CKTGTTGPKCDECLPGNSWHY---GCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGIL 152
Query: 2053 CD--RCPE 2058
C+ RC E
Sbjct: 153 CEKLRCEE 160
Score = 46.4 bits (105), Expect = 0.002
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 15/122 (12%)
Query: 663 CKDRVQGRICNDCKPLYW---NLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQH 719
CK +G+ C C+ Y+ + Q + C +C CN G+++ CN SG C CK
Sbjct: 43 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD--RCNG-SGFCECKTG 99
Query: 720 VGERQCDQCLDG---FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
+CD+CL G Y Q N V C GG+ NN +C C + G C
Sbjct: 100 TTGPKCDECLPGNSWHYGCQPN-VCDNELLHCQNGGTCHNNV-----RCLCPAAYTGILC 153
Query: 777 DQ 778
++
Sbjct: 154 EK 155
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 16/100 (16%)
Query: 1361 CKPNVIGRTCSACRTGYYGFPN--------CRPCHC-PSTAI---CDDNGMCICPKNVEG 1408
CK N G+ C CR GY+ + C C+C P +I C+ +G C C G
Sbjct: 43 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTG 102
Query: 1409 ENCDRCKP-YTFNFDVQRG-CDD--CNCNPLGVVGNQLQC 1444
CD C P ++++ Q CD+ +C G N ++C
Sbjct: 103 PKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRC 142
Score = 41.9 bits (94), Expect = 0.042
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 1478 CTCNRHGTTYDVCDQ-NTAQCY-CKTNVRGQACDTCKEEYF---NLQDDNPDGCTKCFC 1531
C C H D NT C CK N RGQ C+ C+ YF + Q D+ + C +C+C
Sbjct: 20 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC 78
Score = 40.7 bits (91), Expect = 0.097
Identities = 38/147 (25%), Positives = 53/147 (36%), Gaps = 27/147 (18%)
Query: 363 CDPHFST-GNCE--EESGRCE------------CRPEFQPPDCSSCAYGYF--------D 399
C P S+ GNCE S RC C+ + C C GYF D
Sbjct: 10 CIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDD 69
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDG---YYSPECKNCECNTV 456
C C CN G+ + C + G C CK G C+ C G +Y + C+ +
Sbjct: 70 ENVCIECYCNPLGSIHDRCNGS-GFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELL 128
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQ 483
+ C C + Y+G C +
Sbjct: 129 HCQNGGTCHNNVRCLCPAAYTGILCEK 155
Score = 39.5 bits (88), Expect = 0.22
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 11/71 (15%)
Query: 1738 CPRAYRGLSCEQCAEGHYRLPS------GFCVPCQCN---GHSDQCDVNTGICLNCADNT 1788
C RG CE C G++R S C+ C CN D+C+ +G C C T
Sbjct: 43 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN-GSGFC-ECKTGT 100
Query: 1789 IGDHCEFCMSG 1799
G C+ C+ G
Sbjct: 101 TGPKCDECLPG 111
Score = 37.1 bits (82), Expect = 1.2
Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 22/114 (19%)
Query: 613 CKSNFDGAKCDTCREQFYNYPA--------CEECNCDPRGVTASFAGCGSVPAGELCQCK 664
CK N G C+ CR ++ + C EC C+P G + C C+CK
Sbjct: 43 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLG--SIHDRCNG---SGFCECK 97
Query: 665 DRVQGRICNDCKPLYWNLQEYNPFGCEQ--CNCNLAGTLNSLGACNTKSGQCVC 716
G C++C P N Y GC+ C+ L N G C+ + +C+C
Sbjct: 98 TGTTGPKCDECLP--GNSWHY---GCQPNVCDNELLHCQNG-GTCH-NNVRCLC 144
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 77.8 bits (183), Expect = 7e-13
Identities = 92/356 (25%), Positives = 131/356 (36%), Gaps = 69/356 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C DG+ ECK C ++ + + G+C C + GR C++C YP C +
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDEC----VPYPGCVHGS 286
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C EP QC C+ +GG CD+ L+ G C G T
Sbjct: 287 C----VEP-------WQCNCETNWGGLLCDKDLN-----YCGSHHPCT------NGGTCI 324
Query: 559 SCSADG-KCNCLTNFGGAQCDQ---------CSPG--YYKYPDCLSCNCDVSGSIGSTCD 606
+ D +C C + G C++ C+ G ++ P C+C SG G TC
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP-SGWSGPTCA 383
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA----GCGSVPAGELCQ 662
+ + C SN A TC +Q + EC C + V A+ C P
Sbjct: 384 LD-IDECASN-PCAAGGTCVDQVDGF----ECICPEQWVGATCQLDANECEGKPCLNAFS 437
Query: 663 CKDRVQGRICNDCKPLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVG 721
CK+ + G C DC P + + N C + C GT L QCVC + G
Sbjct: 438 CKNLIGGYYC-DCIPGWKGINCHINVNDC-RGQCQHGGTCKDL----VNGYQCVCPRGFG 491
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R C+ D C C GG ++ D CHC G C+
Sbjct: 492 GRHCELERD-----------KCASSPCHSGGLCEDLADGF--HCHCPQGFSGPLCE 534
Score = 72.9 bits (171), Expect = 2e-11
Identities = 138/550 (25%), Positives = 191/550 (34%), Gaps = 101/550 (18%)
Query: 255 RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLD 314
RC N CNK C + + D++ + C EC + ++ +L
Sbjct: 197 RCDENYYSATCNKFCR--PRNDFFGHYTCDQYGNKACMDGWMGKECK--EAVCKQGCNL- 251
Query: 315 INGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEE 374
++G G+C C + +G C++C P +G +P QC NCE
Sbjct: 252 LHGGCTVPGEC-RCSYGWQGRFCDECVPYPGCVHGS------CVEPWQC-------NCET 297
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGK 434
G C D + C + PCT NG + P C C Y+G+
Sbjct: 298 NWGGLLC-----DKDLNYCGSHH-------PCT---NGGTCINAEPDQYRCTCPDGYSGR 342
Query: 435 SCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT 493
+CE E S C N C+ V S +C C S +SG TC +
Sbjct: 343 NCEKAEHACTSNPCANGGSCHEVPS--------GFECHCPSGWSGPTC------ALDIDE 388
Query: 494 CKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCD---------QCLSGYYMQVL--GR 541
C C GT D V G +CIC + G C CL+ + + L G
Sbjct: 389 CASNPCAAGGT---CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGY 445
Query: 542 ERQCVP----CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY------YKYPDC 590
C+P NC C G C L N G QC C G+ + C
Sbjct: 446 YCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVN--GYQC-VCPRGFGGRHCELERDKC 502
Query: 591 LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA 650
S C SG + D CHC F G C+ + CE C + A
Sbjct: 503 ASSPCH-SGGLCEDLADGFHCHCPQGFSGPLCEV------DVDLCEPSPC------RNGA 549
Query: 651 GCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGC-EQCNCNLAGTLNSLGACN 708
C ++ C C D G+ C+ +P GC + GT S G C
Sbjct: 550 RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVID-GCGSDAGPGMPGTAAS-GVCG 607
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G+CV Q G C C GF ++ + C C GG+ + D +C C
Sbjct: 608 -PHGRCV-SQPGGNFSC-ICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD--AFRCFC 662
Query: 768 HSRVEGRRCD 777
S EG CD
Sbjct: 663 PSGWEGELCD 672
Score = 67.7 bits (158), Expect = 7e-10
Identities = 137/576 (23%), Positives = 188/576 (32%), Gaps = 110/576 (19%)
Query: 228 GGRCMCNGHADTCEPADPAGNLNILV----CRCQHNTCGPQC----NKCCSGFEQKKWRI 279
G C HA T P G+ + + C C GP C ++C S
Sbjct: 341 GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400
Query: 280 SQNWDRFSC------EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEG---GGKCLNCQH 330
D F C C EC P ++ I G Y G K +NC
Sbjct: 401 VDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460
Query: 331 NTE--------GINCNKCRPTYY----RPYGKRWDELDVCQPCQCDPHFSTGNCEE--ES 376
N G C Y R +G R EL+ C P S G CE+ +
Sbjct: 461 NVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELER-DKCASSPCHSGGLCEDLADG 519
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDG--LCPCKYNYAGK 434
C C F P C D C+P C G C +G C C ++ GK
Sbjct: 520 FHCHCPQGFSGPLCE------VDVDLCEPSPCR----NGARCYNLEGDYYCACPDDFGGK 569
Query: 435 SCEICEDGYYSPECKNCE-CNTVGSVSYVCDKLTGDC----TCKSKYSGRTCNQCQAGYY 489
+C + + C+ + C + +G C C S+ G C +G+
Sbjct: 570 NCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT 629
Query: 490 ------NYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGRE 542
N C C GT D+V +C C +G+ G CD
Sbjct: 630 GTYCHENIDDCLGQPCRNGGT---CIDEVDAFRCFCPSGWEGELCDT-----------NP 675
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIG 602
C+P DP C + G+C L N CD G + C+ + S G
Sbjct: 676 NDCLP---DP-------CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA-YTCSNG 724
Query: 603 STCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
TC D+G C C + G+ C + +C C G C A
Sbjct: 725 GTCYDSGDTFRCACPPGWKGSTCAVAKNS-----SCLPNPCVNGGT------CVGSGASF 773
Query: 660 LCQCKDRVQGRIC----NDCKPL-YWN----LQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
C C+D +GR C NDC PL +N + N F CE C AG + +
Sbjct: 774 SCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQ 832
Query: 711 SGQC----VCKQHVGERQCDQCLDGFYRLQTNDVFG 742
S C C + +C C G + +V G
Sbjct: 833 SSPCAYGATCVDEINGYRC-SCPPGRAGPRCQEVIG 867
Score = 64.5 bits (150), Expect = 7e-09
Identities = 91/336 (27%), Positives = 124/336 (36%), Gaps = 62/336 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCV-PCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
EC+C ++G C++C + G CV P QCN C+ N G L D N G H
Sbjct: 261 ECRCSYGWQGRFCDECVP-YPGCVHGSCVEPWQCN-----CETNWGGLLCDKDLNYCGSH 314
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C +G + D C CP Y N C+ +E+ +C P G C
Sbjct: 315 -HPCT---NGGTCINAEPDQYRCTCPDGYSGRN----CEKAEH----ACTSNPCANGGSC 362
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ +P + H C P SG D C S C AG C
Sbjct: 363 -------HEVPSGFECH----C-PSGWSGPTCALDIDECAS--NPC------AAGGTCVD 402
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDS--TTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
GF + I + C + +C+ C+ + G CD C P G+N
Sbjct: 403 QVDGF--ECICPEQWVGATC-QLDANECEGKPCLNAFSCKNLIGGYYCD-CIPGWKGINC 458
Query: 1971 GLGCTPCNCGIASESTQCDD-DNG-QCRCAKGVTGKQC----DQCAA------GFWNYTK 2018
+ C G C D NG QC C +G G+ C D+CA+ G
Sbjct: 459 HINVNDCR-GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLA 517
Query: 2019 DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKC 2053
DG HC+C G+S G +C CE P G +C
Sbjct: 518 DGF-HCHCPQGFS-GPLCEVDVDLCEPSPCRNGARC 551
Score = 63.7 bits (148), Expect = 1e-08
Identities = 128/570 (22%), Positives = 189/570 (33%), Gaps = 100/570 (17%)
Query: 254 CRCQHNTCGPQCNKC-----C-SGFEQKKWRIS--QNWDRFSCEP----CNCHNHTT--- 298
CRC + G C++C C G + W+ + NW C+ C H+ T
Sbjct: 262 CRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGG 321
Query: 299 ----------ECT----YDPEIDEKRLSLDINGRYEGGGKC--------LNCQHNTEGIN 336
CT Y EK + GG C +C G
Sbjct: 322 TCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPT 381
Query: 337 C----NKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS 392
C ++C G D++D + C C + C+ ++ CE +P C +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFE-CICPEQWVGATCQLDANECEGKPCLNAFSCKN 440
Query: 393 CAYGYFDYPNCKP------CTCNLNGTEG--EHCTPTDGL-----CPCKYNYAGKSCEIC 439
GY Y +C P C N+N G +H L C C + G+ CE+
Sbjct: 441 LIGGY--YCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE 498
Query: 440 EDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNC 499
D +C + C++ G + D C C +SG C + C+P C
Sbjct: 499 RD-----KCASSPCHSGGLCEDLADGF--HCHCPQGFSGPLCE------VDVDLCEPSPC 545
Query: 500 DTSGTEPSICDDVSGQ--CICKAGFGGPRC----DQCLSGYYMQVLGRERQCVPCNCDPT 553
C ++ G C C FGG C + C G + G P P
Sbjct: 546 RNGAR----CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGM--PG 599
Query: 554 GSTSTSCSADGKCNCLTNFGG---AQCDQCSPGYY---KYPDCLSCNCDVSGSIGSTCDD 607
+ S C G+ C++ GG CD G Y DCL C G+ D
Sbjct: 600 TAASGVCGPHGR--CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV-D 656
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKD-R 666
C C S ++G CDT P C V + C G+ C ++ +
Sbjct: 657 AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL-VNDFYCACDDGWKGKTCHSREFQ 715
Query: 667 VQGRICNDCKPLYWNLQEYN---PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
C++ Y + + P G + C +A + L G CV G
Sbjct: 716 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGS---GAS 772
Query: 724 QCDQCLDGFY-RLQTNDVFGCTECDCDIGG 752
C DG+ R T++ C C GG
Sbjct: 773 FSCICRDGWEGRTCTHNTNDCNPLPCYNGG 802
Score = 60.1 bits (139), Expect = 1e-07
Identities = 99/375 (26%), Positives = 128/375 (34%), Gaps = 67/375 (17%)
Query: 1734 EECQCPRAYRGLSCEQCAEG-HYRLPSGFCVPCQCNGHSDQCDVNTGICLNCAD--NTIG 1790
++C + G CE A+G H P GF P C D C+ + C N A N G
Sbjct: 500 DKCASSPCHSGGLCEDLADGFHCHCPQGFSGPL-CEVDVDLCEPSP--CRNGARCYNLEG 556
Query: 1791 DHCEFCMSGYHGDATVGTPRD-CLICACPM----------PYPSNNFALSCD-----LSE 1834
D+ C + G PR+ C AC + P + C +S+
Sbjct: 557 DYYCACPDDF-GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGD----YCKPCNCSGNI---N 1884
G SC C G+ G C G P T + D +C P G + N
Sbjct: 616 PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTN 674
Query: 1885 PQD--PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADC 1940
P D P C S G C VN+ A C G+ G S+ C A C G
Sbjct: 675 PNDCLPDPCHS-RGRCYDLVNDFYCA----CDDGWKGKTCHSREFQCDAYTCSNGGTCYD 729
Query: 1941 DSTTGTCVCRPGVIGEKC-----DRCAPD---HWGLNTGLGCT-PCNCGIASESTQCDDD 1991
T C C PG G C C P+ + G G G + C C E C +
Sbjct: 730 SGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN 789
Query: 1992 NGQCR---------CAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNA 2038
C C GV +C+ CA GF D C C G + N
Sbjct: 790 TNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEING 848
Query: 2039 TGQCECLPGVIGEKC 2053
+C C PG G +C
Sbjct: 849 Y-RCSCPPGRAGPRC 862
Score = 49.2 bits (112), Expect = 3e-04
Identities = 64/242 (26%), Positives = 88/242 (36%), Gaps = 45/242 (18%)
Query: 1784 CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C D C FC SG+ G+ P DCL P P ++ DL + C C
Sbjct: 651 CIDEVDAFRC-FCPSGWEGELCDTNPNDCL------PDPCHSRGRCYDLVND---FYCAC 700
Query: 1844 QPGYGGARC---EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI--NGDC 1898
G+ G C E+ Y T +GD + C C P GS ++ N C
Sbjct: 701 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR-CACP----PGWKGSTCAVAKNSSC 755
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTC---------V 1948
L N C G G + S +CIC D + C T C +
Sbjct: 756 LP----------NPCVNG--GTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 803
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC-DDDNG-QCRCAKGVTGKQC 2006
C GV +C+ CAP G + + C + C D+ NG +C C G G +C
Sbjct: 804 CVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 862
Query: 2007 DQ 2008
+
Sbjct: 863 QE 864
Score = 43.2 bits (97), Expect = 0.018
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 34/193 (17%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC--SACRTGYYG 1379
C E +S T N RP DF G C+ +G + C +G+ C + C+ G
Sbjct: 198 CDENYYSATC--NKFCRP-RNDFFG--HYTCDQYGNKA-CMDGWMGKECKEAVCKQG--- 248
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
C H C G C C +G CD C PY GC +C V
Sbjct: 249 ---CNLLH----GGCTVPGECRCSYGWQGRFCDECVPYP-------GCVHGSC----VEP 290
Query: 1440 NQLQCEADSGKCACRENVRGRVCDH-CVPGH---YAFPDCYQCTCNRHGTTYDVCDQNTA 1495
Q CE + G C +++ H C G A PD Y+CTC G + C++
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEH 349
Query: 1496 QCYCKTNVRGQAC 1508
C G +C
Sbjct: 350 ACTSNPCANGGSC 362
Score = 42.7 bits (96), Expect = 0.024
Identities = 43/158 (27%), Positives = 55/158 (34%), Gaps = 28/158 (17%)
Query: 1383 CRPCHCPSTAIC---DDNGMCICPKNVEGENC----DRCKPYTFNFDVQRGCDDCNCNP- 1434
C P C + A C + + C CP + G+NC + C G D P
Sbjct: 540 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPG 599
Query: 1435 ---LGVVGNQLQCEADSG---KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD 1488
GV G +C + G C C G C H DC C GT D
Sbjct: 600 TAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC------HENIDDCLGQPCRNGGTCID 653
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
D +C+C + G+ CDT N D PD C
Sbjct: 654 EVD--AFRCFCPSGWEGELCDT------NPNDCLPDPC 683
Score = 40.3 bits (90), Expect = 0.13
Identities = 85/339 (25%), Positives = 112/339 (33%), Gaps = 57/339 (16%)
Query: 1730 ATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNC--ADN 1787
A ++EC G +C +G + V C +++C+ CLN N
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKN 440
Query: 1788 TIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
IG + C+ G+ G DC C +C NG C C G+
Sbjct: 441 LIGGYYCDCIPGWKGINCHINVNDCR-GQC-------QHGGTCKDLVNG--YQCVCPRGF 490
Query: 1848 GGARCEY----CAAG---YYGIPEDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCL 1899
GG CE CA+ G+ E DL G +C P SG + D C+
Sbjct: 491 GGRHCELERDKCASSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEP-----S 543
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTCVCRPGVIGEKC 1958
C N GA C +Y C C D+FG +C C PG
Sbjct: 544 PCRN---GARCYNLEGDYY-----------CACPDDFGGKNCSVPREPC---PGGACRVI 586
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
D C D G + CG N C C G TG C +
Sbjct: 587 DGCGSDAGPGMPGTAASGV-CGPHGRCVSQPGGNFSCICDSGFTGTYCHE--------NI 637
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
D C C G + +A +C C G GE CD P
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAF-RCFCPSGWEGELCDTNP 675
Score = 38.3 bits (85), Expect = 0.52
Identities = 41/150 (27%), Positives = 48/150 (32%), Gaps = 14/150 (9%)
Query: 1920 DAIFSKNCTACICDE---FGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP 1976
D K C +C + C + G C C G G CD C P + G G P
Sbjct: 233 DGWMGKECKEAVCKQGCNLLHGGC-TVPGECRCSYGWQGRFCDECVP-YPGCVHGSCVEP 290
Query: 1977 --CNCGIASESTQCDDDNGQCRCAKGVT-GKQCDQCAAGFWNYT-KDGCDHCNCNTG--Y 2030
CNC CD D C T G C + T DG NC
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Query: 2031 SVGFMCNATGQCECLPGVIGEKCDRCPERW 2060
C G C +P G +C CP W
Sbjct: 351 CTSNPCANGGSCHEVPS--GFEC-HCPSGW 377
Score = 36.7 bits (81), Expect = 1.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 15/61 (24%)
Query: 1449 GKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+C C +GR CD CVP +P C HG+ + QC C+TN G C
Sbjct: 260 GECRCSYGWQGRFCDECVP----YPGCV------HGSCVE-----PWQCNCETNWGGLLC 304
Query: 1509 D 1509
D
Sbjct: 305 D 305
Score = 35.9 bits (79), Expect = 2.8
Identities = 39/153 (25%), Positives = 46/153 (30%), Gaps = 29/153 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG---MCICPKNVEGENCDRCK 1415
C C G+TC + C C + C D+G C CP +G C K
Sbjct: 698 CACDDGWKGKTCHSREF------QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 1416 PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDC 1475
C NP V G S C CR+ GR C H DC
Sbjct: 752 N-----------SSCLPNPC-VNGGTCVGSGASFSCICRDGWEGRTCTHNT------NDC 793
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C G D N +C C G C
Sbjct: 794 NPLPCYNGGICVD--GVNWFRCECAPGFAGPDC 824
Score = 35.1 bits (77), Expect = 4.8
Identities = 47/190 (24%), Positives = 73/190 (38%), Gaps = 38/190 (20%)
Query: 1340 CLC--DFMGST-ELECNTFGGQCPCK-----PNVIGRTCSACRTGYYGFP---NCRPCH- 1387
C+C ++G+T +L+ N G+ PC N+IG C G+ G N C
Sbjct: 409 CICPEQWVGATCQLDANECEGK-PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG 467
Query: 1388 -CPSTAICDD--NG-MCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ 1443
C C D NG C+CP+ G +C +++R D C +P G +
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHC----------ELER--DKCASSPCH-SGGLCE 514
Query: 1444 CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
AD C C + G +C+ V C C Y++ + C C +
Sbjct: 515 DLADGFHCHCPQGFSGPLCEVDV------DLCEPSPCRNGARCYNL--EGDYYCACPDDF 566
Query: 1504 RGQACDTCKE 1513
G+ C +E
Sbjct: 567 GGKNCSVPRE 576
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 77.8 bits (183), Expect = 7e-13
Identities = 92/356 (25%), Positives = 131/356 (36%), Gaps = 69/356 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C DG+ ECK C ++ + + G+C C + GR C++C YP C +
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDEC----VPYPGCVHGS 286
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C EP QC C+ +GG CD+ L+ G C G T
Sbjct: 287 C----VEP-------WQCNCETNWGGLLCDKDLN-----YCGSHHPCT------NGGTCI 324
Query: 559 SCSADG-KCNCLTNFGGAQCDQ---------CSPG--YYKYPDCLSCNCDVSGSIGSTCD 606
+ D +C C + G C++ C+ G ++ P C+C SG G TC
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP-SGWSGPTCA 383
Query: 607 DNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA----GCGSVPAGELCQ 662
+ + C SN A TC +Q + EC C + V A+ C P
Sbjct: 384 LD-IDECASN-PCAAGGTCVDQVDGF----ECICPEQWVGATCQLDANECEGKPCLNAFS 437
Query: 663 CKDRVQGRICNDCKPLYWNLQ-EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVG 721
CK+ + G C DC P + + N C + C GT L QCVC + G
Sbjct: 438 CKNLIGGYYC-DCIPGWKGINCHINVNDC-RGQCQHGGTCKDL----VNGYQCVCPRGFG 491
Query: 722 ERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
R C+ D C C GG ++ D CHC G C+
Sbjct: 492 GRHCELERD-----------KCASSPCHSGGLCEDLADGF--HCHCPQGFSGPLCE 534
Score = 72.9 bits (171), Expect = 2e-11
Identities = 138/550 (25%), Positives = 191/550 (34%), Gaps = 101/550 (18%)
Query: 255 RCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSLD 314
RC N CNK C + + D++ + C EC + ++ +L
Sbjct: 197 RCDENYYSATCNKFCR--PRNDFFGHYTCDQYGNKACMDGWMGKECK--EAVCKQGCNL- 251
Query: 315 INGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEE 374
++G G+C C + +G C++C P +G +P QC NCE
Sbjct: 252 LHGGCTVPGEC-RCSYGWQGRFCDECVPYPGCVHGS------CVEPWQC-------NCET 297
Query: 375 ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGK 434
G C D + C + PCT NG + P C C Y+G+
Sbjct: 298 NWGGLLC-----DKDLNYCGSHH-------PCT---NGGTCINAEPDQYRCTCPDGYSGR 342
Query: 435 SCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPT 493
+CE E S C N C+ V S +C C S +SG TC +
Sbjct: 343 NCEKAEHACTSNPCANGGSCHEVPS--------GFECHCPSGWSGPTC------ALDIDE 388
Query: 494 CKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCD---------QCLSGYYMQVL--GR 541
C C GT D V G +CIC + G C CL+ + + L G
Sbjct: 389 CASNPCAAGGT---CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGY 445
Query: 542 ERQCVP----CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY------YKYPDC 590
C+P NC C G C L N G QC C G+ + C
Sbjct: 446 YCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVN--GYQC-VCPRGFGGRHCELERDKC 502
Query: 591 LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFA 650
S C SG + D CHC F G C+ + CE C + A
Sbjct: 503 ASSPCH-SGGLCEDLADGFHCHCPQGFSGPLCEV------DVDLCEPSPC------RNGA 549
Query: 651 GCGSVPAGELCQCKDRVQGRICN-DCKPLYWNLQEYNPFGC-EQCNCNLAGTLNSLGACN 708
C ++ C C D G+ C+ +P GC + GT S G C
Sbjct: 550 RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVID-GCGSDAGPGMPGTAAS-GVCG 607
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHC 767
G+CV Q G C C GF ++ + C C GG+ + D +C C
Sbjct: 608 -PHGRCV-SQPGGNFSC-ICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD--AFRCFC 662
Query: 768 HSRVEGRRCD 777
S EG CD
Sbjct: 663 PSGWEGELCD 672
Score = 67.7 bits (158), Expect = 7e-10
Identities = 137/576 (23%), Positives = 188/576 (32%), Gaps = 110/576 (19%)
Query: 228 GGRCMCNGHADTCEPADPAGNLNILV----CRCQHNTCGPQC----NKCCSGFEQKKWRI 279
G C HA T P G+ + + C C GP C ++C S
Sbjct: 341 GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400
Query: 280 SQNWDRFSC------EPCNCHNHTTECTYDPEIDEKRLSLDINGRYEG---GGKCLNCQH 330
D F C C EC P ++ I G Y G K +NC
Sbjct: 401 VDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460
Query: 331 NTE--------GINCNKCRPTYY----RPYGKRWDELDVCQPCQCDPHFSTGNCEE--ES 376
N G C Y R +G R EL+ C P S G CE+ +
Sbjct: 461 NVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELER-DKCASSPCHSGGLCEDLADG 519
Query: 377 GRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDG--LCPCKYNYAGK 434
C C F P C D C+P C G C +G C C ++ GK
Sbjct: 520 FHCHCPQGFSGPLCE------VDVDLCEPSPCR----NGARCYNLEGDYYCACPDDFGGK 569
Query: 435 SCEICEDGYYSPECKNCE-CNTVGSVSYVCDKLTGDC----TCKSKYSGRTCNQCQAGYY 489
+C + + C+ + C + +G C C S+ G C +G+
Sbjct: 570 NCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT 629
Query: 490 ------NYPTCKPCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGRE 542
N C C GT D+V +C C +G+ G CD
Sbjct: 630 GTYCHENIDDCLGQPCRNGGT---CIDEVDAFRCFCPSGWEGELCDT-----------NP 675
Query: 543 RQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIG 602
C+P DP C + G+C L N CD G + C+ + S G
Sbjct: 676 NDCLP---DP-------CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA-YTCSNG 724
Query: 603 STCDDNG---LCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGE 659
TC D+G C C + G+ C + +C C G C A
Sbjct: 725 GTCYDSGDTFRCACPPGWKGSTCAVAKNS-----SCLPNPCVNGGT------CVGSGASF 773
Query: 660 LCQCKDRVQGRIC----NDCKPL-YWN----LQEYNPFGCEQCNCNLAGTLNSLGACNTK 710
C C+D +GR C NDC PL +N + N F CE C AG + +
Sbjct: 774 SCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQ 832
Query: 711 SGQC----VCKQHVGERQCDQCLDGFYRLQTNDVFG 742
S C C + +C C G + +V G
Sbjct: 833 SSPCAYGATCVDEINGYRC-SCPPGRAGPRCQEVIG 867
Score = 64.5 bits (150), Expect = 7e-09
Identities = 91/336 (27%), Positives = 124/336 (36%), Gaps = 62/336 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCV-PCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
EC+C ++G C++C + G CV P QCN C+ N G L D N G H
Sbjct: 261 ECRCSYGWQGRFCDECVP-YPGCVHGSCVEPWQCN-----CETNWGGLLCDKDLNYCGSH 314
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C +G + D C CP Y N C+ +E+ +C P G C
Sbjct: 315 -HPCT---NGGTCINAEPDQYRCTCPDGYSGRN----CEKAEH----ACTSNPCANGGSC 362
Query: 1853 EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL 1912
+ +P + H C P SG D C S C AG C
Sbjct: 363 -------HEVPSGFECH----C-PSGWSGPTCALDIDECAS--NPC------AAGGTCVD 402
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDS--TTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
GF + I + C + +C+ C+ + G CD C P G+N
Sbjct: 403 QVDGF--ECICPEQWVGATC-QLDANECEGKPCLNAFSCKNLIGGYYCD-CIPGWKGINC 458
Query: 1971 GLGCTPCNCGIASESTQCDD-DNG-QCRCAKGVTGKQC----DQCAA------GFWNYTK 2018
+ C G C D NG QC C +G G+ C D+CA+ G
Sbjct: 459 HINVNDCR-GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLA 517
Query: 2019 DGCDHCNCNTGYSVGFMCNA-TGQCECLPGVIGEKC 2053
DG HC+C G+S G +C CE P G +C
Sbjct: 518 DGF-HCHCPQGFS-GPLCEVDVDLCEPSPCRNGARC 551
Score = 63.7 bits (148), Expect = 1e-08
Identities = 128/570 (22%), Positives = 189/570 (33%), Gaps = 100/570 (17%)
Query: 254 CRCQHNTCGPQCNKC-----C-SGFEQKKWRIS--QNWDRFSCEP----CNCHNHTT--- 298
CRC + G C++C C G + W+ + NW C+ C H+ T
Sbjct: 262 CRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGG 321
Query: 299 ----------ECT----YDPEIDEKRLSLDINGRYEGGGKC--------LNCQHNTEGIN 336
CT Y EK + GG C +C G
Sbjct: 322 TCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPT 381
Query: 337 C----NKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSS 392
C ++C G D++D + C C + C+ ++ CE +P C +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFE-CICPEQWVGATCQLDANECEGKPCLNAFSCKN 440
Query: 393 CAYGYFDYPNCKP------CTCNLNGTEG--EHCTPTDGL-----CPCKYNYAGKSCEIC 439
GY Y +C P C N+N G +H L C C + G+ CE+
Sbjct: 441 LIGGY--YCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE 498
Query: 440 EDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNC 499
D +C + C++ G + D C C +SG C + C+P C
Sbjct: 499 RD-----KCASSPCHSGGLCEDLADGF--HCHCPQGFSGPLCE------VDVDLCEPSPC 545
Query: 500 DTSGTEPSICDDVSGQ--CICKAGFGGPRC----DQCLSGYYMQVLGRERQCVPCNCDPT 553
C ++ G C C FGG C + C G + G P P
Sbjct: 546 RNGAR----CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGM--PG 599
Query: 554 GSTSTSCSADGKCNCLTNFGG---AQCDQCSPGYY---KYPDCLSCNCDVSGSIGSTCDD 607
+ S C G+ C++ GG CD G Y DCL C G+ D
Sbjct: 600 TAASGVCGPHGR--CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV-D 656
Query: 608 NGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKD-R 666
C C S ++G CDT P C V + C G+ C ++ +
Sbjct: 657 AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL-VNDFYCACDDGWKGKTCHSREFQ 715
Query: 667 VQGRICNDCKPLYWNLQEYN---PFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGER 723
C++ Y + + P G + C +A + L G CV G
Sbjct: 716 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGS---GAS 772
Query: 724 QCDQCLDGFY-RLQTNDVFGCTECDCDIGG 752
C DG+ R T++ C C GG
Sbjct: 773 FSCICRDGWEGRTCTHNTNDCNPLPCYNGG 802
Score = 60.1 bits (139), Expect = 1e-07
Identities = 99/375 (26%), Positives = 128/375 (34%), Gaps = 67/375 (17%)
Query: 1734 EECQCPRAYRGLSCEQCAEG-HYRLPSGFCVPCQCNGHSDQCDVNTGICLNCAD--NTIG 1790
++C + G CE A+G H P GF P C D C+ + C N A N G
Sbjct: 500 DKCASSPCHSGGLCEDLADGFHCHCPQGFSGPL-CEVDVDLCEPSP--CRNGARCYNLEG 556
Query: 1791 DHCEFCMSGYHGDATVGTPRD-CLICACPM----------PYPSNNFALSCD-----LSE 1834
D+ C + G PR+ C AC + P + C +S+
Sbjct: 557 DYYCACPDDF-GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIP---EDTDLHTGD----YCKPCNCSGNI---N 1884
G SC C G+ G C G P T + D +C P G + N
Sbjct: 616 PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTN 674
Query: 1885 PQD--PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN--CTACICDEFGMADC 1940
P D P C S G C VN+ A C G+ G S+ C A C G
Sbjct: 675 PNDCLPDPCHS-RGRCYDLVNDFYCA----CDDGWKGKTCHSREFQCDAYTCSNGGTCYD 729
Query: 1941 DSTTGTCVCRPGVIGEKC-----DRCAPD---HWGLNTGLGCT-PCNCGIASESTQCDDD 1991
T C C PG G C C P+ + G G G + C C E C +
Sbjct: 730 SGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN 789
Query: 1992 NGQCR---------CAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNA 2038
C C GV +C+ CA GF D C C G + N
Sbjct: 790 TNDCNPLPCYNGGICVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEING 848
Query: 2039 TGQCECLPGVIGEKC 2053
+C C PG G +C
Sbjct: 849 Y-RCSCPPGRAGPRC 862
Score = 49.2 bits (112), Expect = 3e-04
Identities = 64/242 (26%), Positives = 88/242 (36%), Gaps = 45/242 (18%)
Query: 1784 CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNC 1843
C D C FC SG+ G+ P DCL P P ++ DL + C C
Sbjct: 651 CIDEVDAFRC-FCPSGWEGELCDTNPNDCL------PDPCHSRGRCYDLVND---FYCAC 700
Query: 1844 QPGYGGARC---EYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSI--NGDC 1898
G+ G C E+ Y T +GD + C C P GS ++ N C
Sbjct: 701 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR-CACP----PGWKGSTCAVAKNSSC 755
Query: 1899 LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTC---------V 1948
L N C G G + S +CIC D + C T C +
Sbjct: 756 LP----------NPCVNG--GTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 803
Query: 1949 CRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQC-DDDNG-QCRCAKGVTGKQC 2006
C GV +C+ CAP G + + C + C D+ NG +C C G G +C
Sbjct: 804 CVDGVNWFRCE-CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 862
Query: 2007 DQ 2008
+
Sbjct: 863 QE 864
Score = 43.2 bits (97), Expect = 0.018
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 34/193 (17%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTC--SACRTGYYG 1379
C E +S T N RP DF G C+ +G + C +G+ C + C+ G
Sbjct: 198 CDENYYSATC--NKFCRP-RNDFFG--HYTCDQYGNKA-CMDGWMGKECKEAVCKQG--- 248
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
C H C G C C +G CD C PY GC +C V
Sbjct: 249 ---CNLLH----GGCTVPGECRCSYGWQGRFCDECVPYP-------GCVHGSC----VEP 290
Query: 1440 NQLQCEADSGKCACRENVRGRVCDH-CVPGH---YAFPDCYQCTCNRHGTTYDVCDQNTA 1495
Q CE + G C +++ H C G A PD Y+CTC G + C++
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEH 349
Query: 1496 QCYCKTNVRGQAC 1508
C G +C
Sbjct: 350 ACTSNPCANGGSC 362
Score = 42.7 bits (96), Expect = 0.024
Identities = 43/158 (27%), Positives = 55/158 (34%), Gaps = 28/158 (17%)
Query: 1383 CRPCHCPSTAIC---DDNGMCICPKNVEGENC----DRCKPYTFNFDVQRGCDDCNCNP- 1434
C P C + A C + + C CP + G+NC + C G D P
Sbjct: 540 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPG 599
Query: 1435 ---LGVVGNQLQCEADSG---KCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD 1488
GV G +C + G C C G C H DC C GT D
Sbjct: 600 TAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC------HENIDDCLGQPCRNGGTCID 653
Query: 1489 VCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGC 1526
D +C+C + G+ CDT N D PD C
Sbjct: 654 EVD--AFRCFCPSGWEGELCDT------NPNDCLPDPC 683
Score = 40.3 bits (90), Expect = 0.13
Identities = 85/339 (25%), Positives = 112/339 (33%), Gaps = 57/339 (16%)
Query: 1730 ATSVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNC--ADN 1787
A ++EC G +C +G + V C +++C+ CLN N
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKN 440
Query: 1788 TIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGY 1847
IG + C+ G+ G DC C +C NG C C G+
Sbjct: 441 LIGGYYCDCIPGWKGINCHINVNDCR-GQC-------QHGGTCKDLVNG--YQCVCPRGF 490
Query: 1848 GGARCEY----CAAG---YYGIPEDTDLHTGDYCK-PCNCSGNINPQDPGSCDSINGDCL 1899
GG CE CA+ G+ E DL G +C P SG + D C+
Sbjct: 491 GGRHCELERDKCASSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCEP-----S 543
Query: 1900 KCVNNTAGAACNLCAPGFYGDAIFSKNCTACIC-DEFGMADCDSTTGTCVCRPGVIGEKC 1958
C N GA C +Y C C D+FG +C C PG
Sbjct: 544 PCRN---GARCYNLEGDYY-----------CACPDDFGGKNCSVPREPC---PGGACRVI 586
Query: 1959 DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTK 2018
D C D G + CG N C C G TG C +
Sbjct: 587 DGCGSDAGPGMPGTAASGV-CGPHGRCVSQPGGNFSCICDSGFTGTYCHE--------NI 637
Query: 2019 DGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCP 2057
D C C G + +A +C C G GE CD P
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAF-RCFCPSGWEGELCDTNP 675
Score = 38.3 bits (85), Expect = 0.52
Identities = 41/150 (27%), Positives = 48/150 (32%), Gaps = 14/150 (9%)
Query: 1920 DAIFSKNCTACICDE---FGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP 1976
D K C +C + C + G C C G G CD C P + G G P
Sbjct: 233 DGWMGKECKEAVCKQGCNLLHGGC-TVPGECRCSYGWQGRFCDECVP-YPGCVHGSCVEP 290
Query: 1977 --CNCGIASESTQCDDDNGQCRCAKGVT-GKQCDQCAAGFWNYT-KDGCDHCNCNTG--Y 2030
CNC CD D C T G C + T DG NC
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Query: 2031 SVGFMCNATGQCECLPGVIGEKCDRCPERW 2060
C G C +P G +C CP W
Sbjct: 351 CTSNPCANGGSCHEVPS--GFEC-HCPSGW 377
Score = 36.7 bits (81), Expect = 1.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 15/61 (24%)
Query: 1449 GKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
G+C C +GR CD CVP +P C HG+ + QC C+TN G C
Sbjct: 260 GECRCSYGWQGRFCDECVP----YPGCV------HGSCVE-----PWQCNCETNWGGLLC 304
Query: 1509 D 1509
D
Sbjct: 305 D 305
Score = 35.9 bits (79), Expect = 2.8
Identities = 39/153 (25%), Positives = 46/153 (30%), Gaps = 29/153 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNG---MCICPKNVEGENCDRCK 1415
C C G+TC + C C + C D+G C CP +G C K
Sbjct: 698 CACDDGWKGKTCHSREF------QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 1416 PYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDC 1475
C NP V G S C CR+ GR C H DC
Sbjct: 752 N-----------SSCLPNPC-VNGGTCVGSGASFSCICRDGWEGRTCTHNT------NDC 793
Query: 1476 YQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
C G D N +C C G C
Sbjct: 794 NPLPCYNGGICVD--GVNWFRCECAPGFAGPDC 824
Score = 35.1 bits (77), Expect = 4.8
Identities = 47/190 (24%), Positives = 73/190 (38%), Gaps = 38/190 (20%)
Query: 1340 CLC--DFMGST-ELECNTFGGQCPCK-----PNVIGRTCSACRTGYYGFP---NCRPCH- 1387
C+C ++G+T +L+ N G+ PC N+IG C G+ G N C
Sbjct: 409 CICPEQWVGATCQLDANECEGK-PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG 467
Query: 1388 -CPSTAICDD--NG-MCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ 1443
C C D NG C+CP+ G +C +++R D C +P G +
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHC----------ELER--DKCASSPCH-SGGLCE 514
Query: 1444 CEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNV 1503
AD C C + G +C+ V C C Y++ + C C +
Sbjct: 515 DLADGFHCHCPQGFSGPLCEVDV------DLCEPSPCRNGARCYNL--EGDYYCACPDDF 566
Query: 1504 RGQACDTCKE 1513
G+ C +E
Sbjct: 567 GGKNCSVPRE 576
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 486 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 542
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 543 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 588
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 589 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 637
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 638 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 695
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 696 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 748
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 749 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 796
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 797 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 842
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 207 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 262
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 263 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 300
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 301 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 350
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 351 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 398
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 399 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 457
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 458 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 513
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 236 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 280
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 281 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 325
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 326 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 372
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 373 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 428
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 429 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 481
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 482 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 537
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 538 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 594
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 595 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 652
Query: 778 QPI 780
I
Sbjct: 653 TNI 655
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 237 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 290
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 291 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 342
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 343 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 398
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 399 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 455
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 456 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 505
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 506 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 556
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 557 TP---CEVIDSCTVAM 569
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 206 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 261
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 262 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 305
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 306 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 352
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 353 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 402
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 403 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 459
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 460 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 515
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 516 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 547
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 174 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 222
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 223 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 271
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 272 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 329
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 330 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 388
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 389 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 444
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 445 CQNDASCRDLVNGYRCICP 463
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 486 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 542
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 543 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 602
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 603 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 653
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 536 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 591
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 592 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 648
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 649 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 701
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 702 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 761
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 762 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 804
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 805 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 848
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 616 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 673
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 674 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 723
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 724 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 778
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 779 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 836
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 837 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 875
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 342 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 395
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 396 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 454
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 455 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 509
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 384 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 440
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 441 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 498
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 499 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 548
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 549 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 601
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 602 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 657
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 658 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 684
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 508 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 559
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 560 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 619
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 620 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 678
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 679 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 738
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 739 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 798
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 799 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 856
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 857 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 898
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 577 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 636
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 637 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 683
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 684 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 731
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 385 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 441
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 442 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 488
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 489 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 536
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 537 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 566
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 207 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 263
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 264 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 320
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 321 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 371
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 236 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 294
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 295 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 352
Query: 2048 VIGEKC 2053
G C
Sbjct: 353 WTGPTC 358
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 472
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 473 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 528
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 235
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 236 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 284
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 342
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 343 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 402 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 457
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 458 CQNDASCRDLVNGYRCICP 476
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 888
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 355 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 467
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 468 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 522
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 220 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 276
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 277 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 472
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 473 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 528
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 235
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 236 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 284
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 342
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 343 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 402 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 457
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 458 CQNDASCRDLVNGYRCICP 476
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 888
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 355 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 467
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 468 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 522
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 220 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 276
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 277 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 472
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 473 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 528
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 235
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 236 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 284
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 342
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 343 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 402 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 457
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 458 CQNDASCRDLVNGYRCICP 476
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 888
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 355 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 467
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 468 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 522
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 220 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 276
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 277 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 472
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 473 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 528
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 235
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 236 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 284
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 342
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 343 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 402 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 457
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 458 CQNDASCRDLVNGYRCICP 476
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 888
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 355 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 467
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 468 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 522
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 220 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 276
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 277 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 472
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 473 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 528
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 235
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 236 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 284
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 342
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 343 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 402 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 457
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 458 CQNDASCRDLVNGYRCICP 476
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIRDGAKWDDDCNTCQCLNG 888
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 355 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 467
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 468 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 522
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IRDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 220 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 276
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 277 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 76.6 bits (180), Expect = 2e-12
Identities = 145/558 (25%), Positives = 195/558 (34%), Gaps = 112/558 (20%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKRLSL 313
C+C G C + + Q D C C+ +IDE S
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP 615
Query: 314 DIN-GR---YEGGGKCLNCQHNTEGINCN-KCRPTYYRP--YGKRWDELDVCQPCQCDPH 366
+N GR G +C NCQ T G+NC P +G D ++ C C P
Sbjct: 616 CLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPCIHGICMDGIN-RYSCVCSPG 673
Query: 367 FSTGNCEEESGRCECRPEFQPPDCSSCAYGYF----DYPNCKPCTCNLNGTEGEHC---T 419
F+ C + C P + C + G+ + P+ C +N C
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Query: 420 PTDGL----CPCKYNYAGKSCEICEDGYYSPECKN------------CECNTVGSVSYVC 463
T GL C C + G +CE+ ++ S C+N C C G Y C
Sbjct: 734 CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKK-GFKGYNC 792
Query: 464 DKLTGDC---------TCKSKYSGRTCNQCQAGY--YNYPT----CKPCNCDTSGTEPSI 508
+C TC SG TC+ C Y N T C P C+ +
Sbjct: 793 QVNIDECASNPCLNQGTCFDDISGYTCH-CVLPYTGKNCQTVLAPCSPNPCENAAVCKES 851
Query: 509 CDDVSGQCICKAGFGGPRC----DQCLSGYYMQ--VLGRERQCVPCNCDPTGSTSTSCSA 562
+ S C+C G+ G RC D+C+S M + + C C P G + C
Sbjct: 852 PNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCEC-PPGFSGMDCEE 910
Query: 563 DGKCNCLTN---FGGAQCD-------QCSPGYY--KYP----DCLSCNCDVSGSIGSTCD 606
D +CL N GG+ D C PG+ KY +CLS C G TC
Sbjct: 911 DID-DCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQTDMNECLSEPC----KNGGTCS 965
Query: 607 D---NGLCHCKSNFDGAKCDT----CRE-QFYNYPACEE------CNCDPRGVTASFA-- 650
D + C C++ FDG C+ C E +N C + C C P G T SF
Sbjct: 966 DYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLH 1024
Query: 651 ---GCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
C S P C D + C+ C P G NC L S C
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCS-C-----------PLGYTGKNCQTLVNLCSRSPC 1072
Query: 708 NTKSGQCVCKQHVGERQC 725
K G CV K+ E QC
Sbjct: 1073 KNK-GTCVQKK--AESQC 1087
Score = 71.7 bits (168), Expect = 5e-11
Identities = 137/575 (23%), Positives = 199/575 (34%), Gaps = 103/575 (17%)
Query: 254 CRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEKR 310
C CQ G +C + C S + ++FSC+ C T + +++E
Sbjct: 131 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCK---CLTGFTGQKCETDVNE-- 185
Query: 311 LSLDINGRYEGGGKCLN--------CQHNTEGINCNK----CRPTYYRPYGKRWDELDVC 358
DI G + GG CLN C G C+ C P+ G D
Sbjct: 186 --CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 359 QPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNG---TEG 415
C C P F CE C P + + C G Y NC+ C G TE
Sbjct: 244 FECNCLPGFEGSTCERNIDDC---PNHRCQNGGVCVDGVNTY-NCR-CPPQWTGQFCTED 298
Query: 416 -EHCTPTDGLC----PCKYNYAGKSCEICEDGYYSPECK----NCECNTVGSVSYVCDKL 466
+ C C C G C +C +G+ +C +C + S D++
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGC-VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 467 TG-DCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQ--CICKAGFG 523
C C +G C+ A N P K CDT + ++GQ C C G+
Sbjct: 358 ASFSCMCPEGKAGLLCHLDDACISN-PCHKGALCDT--------NPLNGQYICTCPQGYK 408
Query: 524 GPRC----DQCL---------SGYYMQVLGR-ERQCVP------CNCDPTGSTSTSCSAD 563
G C D+C +G + G +C+ C D S C D
Sbjct: 409 GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468
Query: 564 GKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCD 623
CL GG C C PG+ + C +++ + C +NG C K N +C
Sbjct: 469 --ATCLDKIGGFTC-LCMPGF----KGVHCELEINECQSNPCVNNGQCVDKVN--RFQC- 518
Query: 624 TCREQFYNYPAC----EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLY 679
C F P C ++C+ P + A C P G CQC G +C +
Sbjct: 519 LCPPGFTG-PVCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEE----- 569
Query: 680 WNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCL-DGFYRLQTN 738
N+ +P C C G + CN +C + E CL DG +
Sbjct: 570 -NIDNCDPDPCHHGQCQ-DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDG----RCI 623
Query: 739 DVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEG 773
D+ +C+C G S NC+ C + + G
Sbjct: 624 DLVNGYQCNCQPGTS-GVNCEINFDDCASNPCIHG 657
Score = 64.5 bits (150), Expect = 7e-09
Identities = 112/468 (23%), Positives = 162/468 (34%), Gaps = 84/468 (17%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSS--------CAYGY------FDYPNCKPC 406
C C P F +CE E C+ P C C G+ D +C
Sbjct: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 407 TCNLNGTEG-EHCTPTDGLCPCKYNYAGKSCE----ICE-DGYYSPECKN------CECN 454
C LNG + +H P C C + G CE C+ D + +C++ C CN
Sbjct: 540 PC-LNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN 596
Query: 455 TVGSVSYVCDKLTGDC---------TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE 505
G + +C +C C +G CN CQ G C+ N D +
Sbjct: 597 P-GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN-CQPGTSGV-NCE-INFDDCASN 652
Query: 506 P---SICDDVSGQ--CICKAGFGGPRCDQCLSGYYMQVLGRERQCV------PCNCDPTG 554
P IC D + C+C GF G RC+ + + C+ C C P G
Sbjct: 653 PCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCIC-PEG 711
Query: 555 STSTSC-SADGKC--------NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC 605
SC S +C NC G +C C G+ ++C D + + + C
Sbjct: 712 PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC-LCDAGWVG----INCEVDKNECLSNPC 766
Query: 606 DDNGLCHCKSNFDGAKCDTCREQFYNYPA---CEECNCDPRGVTASFAGCGSVPAGELCQ 662
+ G C N G +C TC++ F Y +EC +P + C +G C
Sbjct: 767 QNGGTCDNLVN--GYRC-TCKKGFKGYNCQVNIDECASNP---CLNQGTCFDDISGYTCH 820
Query: 663 CKDRVQGRICND-CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLG----ACNTKSGQCVCK 717
C G+ C P N E E N L + G C +C+ K
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 718 QHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQC 765
+ C G Y + F +C+ DI + N C + G C
Sbjct: 881 PCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPC-QNGGSC 926
Score = 62.9 bits (146), Expect = 2e-08
Identities = 96/400 (24%), Positives = 132/400 (33%), Gaps = 78/400 (19%)
Query: 387 PPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
P C GY N C NGT G C C + G+ C+ +
Sbjct: 22 PAHALQCRDGYEPCVNEGMCVTYHNGT---------GYCKCPEGFLGEYCQ------HRD 66
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC----NCDTS 502
C+ C G+ V + G TC+ SG T CQ Y T PC C
Sbjct: 67 PCEKNRCQNGGTC--VAQAMLGKATCRCA-SGFTGEDCQ-----YSTSHPCFVSRPCLNG 118
Query: 503 GTEPSICDDVSGQCICKAGFGGPRC---DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTS 559
GT + D +C C+ GF G C D CLS PC GST T+
Sbjct: 119 GTCHMLSRDTY-ECTCQVGFTGKECQWTDACLSH-------------PC---ANGSTCTT 161
Query: 560 CSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTC---DDNGLCHCKSN 616
+ C CLT F G +C+ D C+ G TC + C C
Sbjct: 162 VANQFSCKCLTGFTGQKCE---------TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 617 FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCK 676
F G CD+ P C G +F C +P E C+ + + C+
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTG-DFTFE-CNCLPGFEGSTCERNIDDCPNHRCQ 270
Query: 677 PLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQ 736
+ N + C +C G C +C+ Q + C +G
Sbjct: 271 NGGVCVDGVNTYNC-RCPPQWTGQF-----CTEDVDECLL-------QPNACQNGGTCAN 317
Query: 737 TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
N +GC C + G ++C + C S G C
Sbjct: 318 RNGGYGCV-C---VNGWSGDDCSENIDDCAFASCTPGSTC 353
Score = 62.1 bits (144), Expect = 4e-08
Identities = 90/342 (26%), Positives = 125/342 (36%), Gaps = 64/342 (18%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHY-RLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNTIG 1790
EC G +C+ G+ GF C + D+C N CLN C D+ G
Sbjct: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGF-KGYNCQVNIDECASNP--CLNQGTCFDDISG 816
Query: 1791 DHCEFCMSGYHGDATVGTPRDCLICACPM-PYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C C+ Y G ++C P P P N A+ C S N +C C PG+ G
Sbjct: 817 YTCH-CVLPYTG-------KNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQG 867
Query: 1850 ARC----EYCAAG---YYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--- 1899
RC + C + +G+ +T G Y C C + D C+ DCL
Sbjct: 868 QRCTIDIDECISKPCMNHGLCHNTQ---GSYM--CECPPGFSGMD---CEEDIDDCLANP 919
Query: 1900 -----KCVNNTAGAACNLCAPGFYGDAIFS--KNCTACICDEFGMADCDSTTGTCVCRPG 1952
C++ +C LC PGF GD + C + C G + TC C+ G
Sbjct: 920 CQNGGSCMDGVNTFSC-LCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAA 2011
G C+ +N CT +C + T D N C C G TG C
Sbjct: 979 FDGVHCEN------NINE---CTESSC--FNGGTCVDGINSFSCLCPVGFTGSFC----- 1022
Query: 2012 GFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
+ + H N G V + T +C C G G+ C
Sbjct: 1023 --LHEINECSSHPCLNEGTCVDGL--GTYRCSCPLGYTGKNC 1060
Score = 61.7 bits (143), Expect = 5e-08
Identities = 99/429 (23%), Positives = 150/429 (34%), Gaps = 74/429 (17%)
Query: 379 CECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGL--CPCKYNYAGKSC 436
C C ++ DC+ D C N G+ C TDG C C YAG C
Sbjct: 401 CTCPQGYKGADCTE------DVDECAMANSNPCEHAGK-CVNTDGAFHCECLKGYAGPRC 453
Query: 437 EICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKP 496
E+ + +S C+N D TC K G TC C G+
Sbjct: 454 EMDINECHSDPCQN------------------DATCLDKIGGFTC-LCMPGFKGV----H 490
Query: 497 CNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGST 556
C + + + + C + +GQC+ K C +G Q+ + PC G+
Sbjct: 491 CELEINECQSNPCVN-NGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC---LNGAK 546
Query: 557 STSCSADGKCNCLTNFGGAQC----DQCSPGYYKYPDC------LSCNCDVSGSIGSTCD 606
+C C T F G C D C P + C +C C+ G +G+ C
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICN-PGYMGAICS 605
Query: 607 DN-GLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP--RGVTA--SFAGCGSVPAGELC 661
D C+ + +C + +CNC P GV +F C S P
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGY-------QCNCQPGTSGVNCEINFDDCASNPCIHGI 658
Query: 662 QCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSG-QCVCKQHV 720
C D + C C P + Q N ++C N N +G +C+C +
Sbjct: 659 -CMDGINRYSC-VCSPGFTG-QRCN-IDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
Query: 721 GERQC----DQCLDG--FYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGR 774
C ++CL + T + G +C CD G + NC+ +C + G
Sbjct: 713 HHPSCYSQVNECLSNPCIHGNCTGGLSG-YKCLCD-AGWVGINCEVDKNECLSNPCQNGG 770
Query: 775 RCDQPIRAH 783
CD + +
Sbjct: 771 TCDNLVNGY 779
Score = 61.3 bits (142), Expect = 6e-08
Identities = 86/344 (25%), Positives = 114/344 (33%), Gaps = 42/344 (12%)
Query: 1733 VEECQC-PRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
+ ECQ P G ++ P GF P C D C CLN C D+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPV-CQIDIDDCSSTP--CLNGAKCIDHP 551
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
G C+ C +G+ G +C P P ++ + +C C PGY
Sbjct: 552 NGYECQ-CATGFTGVLCEENIDNC------DPDPCHHGQCQDGIDS----YTCICNPGYM 600
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK--PCNC----SG---NINPQDPGSCDSINGDCL 1899
GA C Y P D D CNC SG IN D S I+G C+
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 1900 KCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TCVCRPGVIGE 1956
+N + C +C+PGF G I C + C + G + G C+C G
Sbjct: 661 DGINRYS---C-VCSPGFTGQRCNIDIDECASNPCRK-GATCINGVNGFRCICPEGPHHP 715
Query: 1957 KC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQC 2009
C + C + H GL C C C+ D +C G CD
Sbjct: 716 SCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL 775
Query: 2010 AAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC 2053
G+ K G NC Q C + G C
Sbjct: 776 VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
Score = 60.1 bits (139), Expect = 1e-07
Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 46/304 (15%)
Query: 1784 CADNTI-GDHCEFCMSGYHG-DATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C N + G + C GY G D T D CA P + A C ++ +G+ C
Sbjct: 390 CDTNPLNGQYICTCPQGYKGADCT----EDVDECAMANSNPCEH-AGKC-VNTDGAF-HC 442
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGD-------YCKP----CNCSGNINPQDPGS 1890
C GY G RCE + P D D C P +C IN
Sbjct: 443 ECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNP 502
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDA--IFSKNCTACICDEFGMADCDSTTG-TC 1947
C + NG C+ VN C LC PGF G I +C++ C G D G C
Sbjct: 503 CVN-NGQCVDKVNRFQ---C-LCPPGFTGPVCQIDIDDCSSTPCLN-GAKCIDHPNGYEC 556
Query: 1948 VCRPGVIGEKC----DRCAPD---HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
C G G C D C PD H G+ C C C D +C +
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYS--------VGFMCNATGQ--CECLPGVIG 2050
+ +C G+ + G NC + G + + C C PG G
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 2051 EKCD 2054
++C+
Sbjct: 677 QRCN 680
Score = 57.2 bits (132), Expect = 1e-06
Identities = 87/351 (24%), Positives = 120/351 (34%), Gaps = 57/351 (16%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
EC C + G C Q + P C + C TG + + + C+
Sbjct: 130 ECTCQVGFTGKEC-QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE-CD 187
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPS---NNFALSCDLSE--NGSL--------ISC 1841
HG + P C CP + ++ + C S NG C
Sbjct: 188 IPGHCQHGGTCLNLPGSYQ-CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 1842 NCQPGYGGARCE---------YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD 1892
NC PG+ G+ CE C G G+ D ++T + P +G +D C
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNG--GVCVD-GVNTYNCRCPPQWTGQFCTEDVDECL 303
Query: 1893 SINGDCLK---CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C C N G C +C G+ GD +C+ I D+ A C + TC+
Sbjct: 304 LQPNACQNGGTCANRNGGYGC-VCVNGWSGD-----DCSENI-DDCAFASC-TPGSTCID 355
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD--NGQ--CRCAKGVTGKQ 2005
R V C C GL L C + CD + NGQ C C +G G
Sbjct: 356 R--VASFSC-MCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGAD 411
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATG--QCECLPGVIGEKCD 2054
C + D C N N G N G CECL G G +C+
Sbjct: 412 CTE--------DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
Score = 56.8 bits (131), Expect = 1e-06
Identities = 92/387 (23%), Positives = 131/387 (33%), Gaps = 62/387 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + Y G CE + C C + D G C G HCE
Sbjct: 442 CECLKGYAGPRCE--------MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
Query: 1796 CMSGYHGDATVGTPR-----DCLICACPMPYPSNNFALSC-DLSENGSLISCNCQPGYGG 1849
++ + V + + C CP + + D S L C G
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG 553
Query: 1850 ARCEYCAAGYYGI--PEDTDLHTGDYCKPCNCSGNINPQ----DPGSCDSINGD------ 1897
C+ CA G+ G+ E+ D D C C I+ +PG +I D
Sbjct: 554 YECQ-CATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 1898 ---CL---KCVNNTAGAACNLCAPGFYG--DAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
CL +C++ G CN C PG G I +C + C G+ +CVC
Sbjct: 613 SSPCLNDGRCIDLVNGYQCN-CQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVC 670
Query: 1950 RPGVIGEKC----DRCA--PDHWGLN--TGLGCTPCNCGIASESTQCDDDNGQC------ 1995
PG G++C D CA P G G+ C C C +C
Sbjct: 671 SPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
Query: 1996 --RCAKGVTGKQCDQCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVI 2049
C G++G +C C AG+ K+ C C G + + N +C C G
Sbjct: 731 HGNCTGGLSGYKC-LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY-RCTCKKGFK 788
Query: 2050 GEKCDRCPERWVLIPQEGCLECDSCTD 2076
G C + P CL +C D
Sbjct: 789 GYNCQVNIDECASNP---CLNQGTCFD 812
Score = 56.8 bits (131), Expect = 1e-06
Identities = 81/325 (24%), Positives = 111/325 (34%), Gaps = 50/325 (15%)
Query: 361 CQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTP 420
C+C P FS +CEE+ C P C D N C C L G G+
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSC-------MDGVNTFSCLC-LPGFTGDKYQT 948
Query: 421 TDGLC---PCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYS 477
C PCK G +C + Y C+C G C+ +CT S ++
Sbjct: 949 DMNECLSEPCK---NGGTCSDYVNSY------TCKCQ-AGFDGVHCENNINECTESSCFN 998
Query: 478 GRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCI----CKAGFGGPRCDQCLSG 533
G TC G ++ P S I + S C+ C G G RC C G
Sbjct: 999 GGTCVD---GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLG 1054
Query: 534 YY-MQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS 592
Y C C G T A+ +C C + + GA CD P +
Sbjct: 1055 YTGKNCQTLVNLCSRSPCKNKG-TCVQKKAESQCLCPSGWAGAYCD--------VP---N 1102
Query: 593 CNCDVSGS-----IGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTA 647
+CD++ S + C +G+C N +C Y +EC +P
Sbjct: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP---CQ 1159
Query: 648 SFAGCGSVPAGELCQCKDRVQGRIC 672
A C G C+C QG C
Sbjct: 1160 HGATCSDFIGGYRCECVPGYQGVNC 1184
Score = 52.4 bits (120), Expect = 3e-05
Identities = 93/374 (24%), Positives = 125/374 (33%), Gaps = 67/374 (17%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C Y G C ++ + PC +G D+ G NC T G +CE
Sbjct: 593 CICNPGYMGAICSD------QIDECYSSPCLNDGRC--IDLVNGYQCNCQPGTSGVNCEI 644
Query: 1796 ----CMSG--YHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGG 1849
C S HG G R +C+ N + + + N C G G
Sbjct: 645 NFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID-ECASNPCRKGATCINGVNG 703
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPC---NCSGNINPQ----DPG----SCDSINGDC 1898
RC C G + P PC NC+G ++ D G +C+ +C
Sbjct: 704 FRC-ICPEGPHH-PSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
Query: 1899 LK--------CVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
L C N G C C GF G NC I DE C GTC
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCT-CKKGFKG-----YNCQVNI-DECASNPC-LNQGTCF-- 811
Query: 1951 PGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD----DNGQCRCAKGVTGKQC 2006
+ G C C + G N PC+ + C + ++ C CA G G++C
Sbjct: 812 DDISGYTC-HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Query: 2007 DQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ--CECLPGVIGEKCDRCPERWVLIP 2064
T D D C + G N G CEC PG G C+ + + P
Sbjct: 871 ----------TID-IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Query: 2065 QEGCLECDSCTDAL 2078
C SC D +
Sbjct: 920 ---CQNGGSCMDGV 930
Score = 51.2 bits (117), Expect = 7e-05
Identities = 86/349 (24%), Positives = 125/349 (35%), Gaps = 56/349 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP + G+ CE+ + PCQ NG S VNT CL C GD +
Sbjct: 897 CECPPGFSGMDCEE------DIDDCLANPCQ-NGGSCMDGVNTFSCL-CLPGFTGDKYQT 948
Query: 1796 CMSGYHGDATV--GTPRDCL---ICACPMPYPSNNFALSC-DLSENGSLISCNCQPGYGG 1849
M+ + GT D + C C + + + + +E+ C G
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINS 1008
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSC-DSINGDCLKCVNNTAGA 1908
C C G+ G LH + C C G+C D + C G
Sbjct: 1009 FSC-LCPVGFTG---SFCLHEINECSSHPCLNE------GTCVDGLGTYRCSCPLGYTGK 1058
Query: 1909 AC----NLCAPG---FYGDAIFSKNCTACICDE-FGMADCDSTTGTC---VCRPGVIGEK 1957
C NLC+ G + K + C+C + A CD +C R GV+ E
Sbjct: 1059 NCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEH 1118
Query: 1958 CDRCAPDHWGLNTGLGCTP-CNCGIASESTQCDDDNGQCR---CAKGVT------GKQCD 2007
C H G+ G T C C + + C++ +C C G T G +C
Sbjct: 1119 L--C--QHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC- 1173
Query: 2008 QCAAGF----WNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEK 2052
+C G+ Y D C + C G + + N +C C PG G K
Sbjct: 1174 ECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF-KCSCPPGTRGMK 1221
Score = 48.0 bits (109), Expect = 6e-04
Identities = 73/295 (24%), Positives = 108/295 (36%), Gaps = 67/295 (22%)
Query: 1766 QCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNN 1825
QC + C VN G+C+ + T +C+ C G+ G+ C P N
Sbjct: 27 QCRDGYEPC-VNEGMCVTYHNGT--GYCK-CPEGFLGE----------YCQHRDPCEKNR 72
Query: 1826 FALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYC---KPCNCSGN 1882
C +NG +C Q G A C CA+G+ G ED T C +PC
Sbjct: 73 ----C---QNGG--TCVAQAMLGKATCR-CASGFTG--EDCQYSTSHPCFVSRPC----- 115
Query: 1883 INPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYG-DAIFSKNCTACICDEFGMADCD 1941
+ G+C ++ D +C C GF G + ++ C + C
Sbjct: 116 ---LNGGTCHMLSRDTYECT----------CQVGFTGKECQWTDACLSHPCANGSTCTTV 162
Query: 1942 STTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAKG 2000
+ +C C G G+KC+ + C P +C QC+C +G
Sbjct: 163 ANQFSCKCLTGFTGQKCETDVNE---------CDIPGHCQHGGTCLNLPGSY-QCQCPQG 212
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
TG+ CD Y C C G + + T +C CLPG G C+R
Sbjct: 213 FTGQYCDSL------YVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
Score = 45.6 bits (103), Expect = 0.003
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 27/149 (18%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNC--RPCHCPSTAICDDNGM-CICPKNVEGENC-DRC 1414
C C P G+ C+ C PC +T I NG CICP+ +C +
Sbjct: 668 CVCSPGFTGQRCNI------DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Query: 1415 KPYTFNFDVQRGCDD------CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
N + C C C+ G VG + CE D +C G CD+ V G
Sbjct: 722 NECLSNPCIHGNCTGGLSGYKCLCDA-GWVG--INCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Y+CTC + Y+ C N +C
Sbjct: 779 -------YRCTCKKGFKGYN-CQVNIDEC 799
Score = 45.6 bits (103), Expect = 0.003
Identities = 96/419 (22%), Positives = 142/419 (33%), Gaps = 72/419 (17%)
Query: 242 PADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPCNCHN--HTTE 299
P P N VC+ N C C G++ ++ I + D +PC H H T+
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTC-LCAPGWQGQRCTI--DIDECISKPCMNHGLCHNTQ 892
Query: 300 CTYDPEIDEKRLSLDINGRYEG--GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDV 357
+Y E +D + C N +G+N C K +++
Sbjct: 893 GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQTDMNE 952
Query: 358 C--QPCQ----CDPHFSTGNCEEESGRCECRPEFQPPDC--SSCAYG--YFDYPNCKPCT 407
C +PC+ C + ++ C+ ++G E +C SSC G D N C
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
Query: 408 CNLNGTEGEHC----------------TPTDGL----CPCKYNYAGKSCEICEDGYYSPE 447
C + G G C T DGL C C Y GK+C+ +
Sbjct: 1013 CPV-GFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVN-----L 1066
Query: 448 CKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPS 507
C C G+ V K C C S ++G C+ +C
Sbjct: 1067 CSRSPCKNKGTC--VQKKAESQCLCPSGWAGAYCDVPNV------SCDIAASRRGVLVEH 1118
Query: 508 ICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT--GSTSTSCSADGK 565
+C SG CI G QC GY E Q C +P G+T + +
Sbjct: 1119 LCQH-SGVCI---NAGNTHYCQCPLGYTGSYC--EEQLDECASNPCQHGATCSDFIGGYR 1172
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD---NGLCHCKSNFDGAK 621
C C+ + G C+ Y+ +C + C G TC D + C C G K
Sbjct: 1173 CECVPGYQGVNCE------YEVDECQNQPC----QNGGTCIDLVNHFKCSCPPGTRGMK 1221
Score = 41.5 bits (93), Expect = 0.056
Identities = 51/184 (27%), Positives = 66/184 (35%), Gaps = 26/184 (14%)
Query: 1336 GARPCLC--DFMG-STELECNTFGGQCPCKPN-----VIGRTCSACRTGYYGFPNCRPC- 1386
G CLC F G ELE N PC N + R C G+ G P C+
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSN-PCVNNGQCVDKVNRFQCLCPPGFTG-PVCQIDI 533
Query: 1387 -HCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE 1445
C ST C + CI N G C +T + D+C+ +P Q Q
Sbjct: 534 DDCSSTP-CLNGAKCIDHPN--GYECQCATGFT-GVLCEENIDNCDPDPCH--HGQCQDG 587
Query: 1446 ADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRG 1505
DS C C G +C + +CY C G D+ N QC C+ G
Sbjct: 588 IDSYTCICNPGYMGAICSDQI------DECYSSPCLNDGRCIDLV--NGYQCNCQPGTSG 639
Query: 1506 QACD 1509
C+
Sbjct: 640 VNCE 643
Score = 40.3 bits (90), Expect = 0.13
Identities = 51/200 (25%), Positives = 70/200 (35%), Gaps = 34/200 (17%)
Query: 1359 CPCKPNVIGRTCSACRTGYYGFPNCRPC--HCPSTAICDDNGMCICPKNVEGENCDRCKP 1416
C PN TC C G+ G C C S C ++G+C N +G C P
Sbjct: 848 CKESPNFESYTC-LCAPGWQG-QRCTIDIDECISKP-CMNHGLC---HNTQGSYMCECPP 901
Query: 1417 YTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY 1476
D + DDC NP C+ + G C N +C G D
Sbjct: 902 GFSGMDCEEDIDDCLANP---------CQ-NGGSCMDGVNTFSCLCLPGFTGDKYQTDMN 951
Query: 1477 QC---TCNRHGTTYDVCDQNTAQC-------YCKTNVR---GQAC---DTCKEEYFNLQD 1520
+C C GT D + T +C +C+ N+ +C TC + +
Sbjct: 952 ECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSC 1011
Query: 1521 DNPDGCTKCFCFGKTTRCSS 1540
P G T FC + CSS
Sbjct: 1012 LCPVGFTGSFCLHEINECSS 1031
Score = 38.3 bits (85), Expect = 0.52
Identities = 73/301 (24%), Positives = 95/301 (31%), Gaps = 42/301 (13%)
Query: 1776 VNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSEN 1835
+N G+C NT G + C G+ G DCL C N SC +
Sbjct: 883 MNHGLC----HNTQGSYMCECPPGFSGMDCEEDIDDCLANPC------QNGG-SC--MDG 929
Query: 1836 GSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDY-----CK------PCNCSGNIN 1884
+ SC C PG+ G + + P DY CK +C NIN
Sbjct: 930 VNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNIN 989
Query: 1885 PQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK--NCTACICDEFGMADCDS 1942
SC NG CV+ +C LC GF G + C++ C G
Sbjct: 990 ECTESSC--FNGGT--CVDGINSFSC-LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044
Query: 1943 TTGTCVCRPGVIGEKCDR----CAPDHWGLNTGLGC-----TPCNCGIASESTQCDDDNG 1993
T C C G G+ C C+ N G + C C CD N
Sbjct: 1045 GTYRCSCPLGYTGKNCQTLVNLCSRSPCK-NKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103
Query: 1994 QCRCAKGVTGKQCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATGQCECLPGVIGEK 2052
C A G + G H C C GY+ + +C P G
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGAT 1163
Query: 2053 C 2053
C
Sbjct: 1164 C 1164
Score = 35.5 bits (78), Expect = 3.6
Identities = 51/216 (23%), Positives = 74/216 (34%), Gaps = 30/216 (13%)
Query: 1301 REFIEQCASYNYYIS-PNETGLCREAMFSITSEYNSGARPC---LCDFMGSTELECNTFG 1356
R+ E C + ++ N TG C+ EY PC C G+ +
Sbjct: 29 RDGYEPCVNEGMCVTYHNGTGYCK-CPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK 87
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTA--ICDDNGMCICPKNVEGENCDRC 1414
C C G C T + F + RPC T + D C C G+ C
Sbjct: 88 ATCRCASGFTGEDCQYS-TSHPCFVS-RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-- 143
Query: 1415 KPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPD 1474
+T + + C N + V NQ C+ +G + CD +PGH
Sbjct: 144 --WT-DACLSHPC--ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD--IPGH----- 191
Query: 1475 CYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C GT ++ + QC C GQ CD+
Sbjct: 192 -----CQHGGTCLNL--PGSYQCQCPQGFTGQYCDS 220
>BC009326-1|AAH09326.2| 595|Homo sapiens SCARF2 protein protein.
Length = 595
Score = 76.6 bits (180), Expect = 2e-12
Identities = 67/215 (31%), Positives = 94/215 (43%), Gaps = 49/215 (22%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY- 1854
C +G++G +G R C C P C ++E L C+PG+ G +C+
Sbjct: 2 CPAGFYG---LGCRRRCGQCKGQQP---------CTVAEGRCL---TCEPGWNGTKCDQP 46
Query: 1855 CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-C 1913
CA G+YG + H C PC +D +C+ + G C +C G C C
Sbjct: 47 CATGFYG---EGCSHR---CPPC--------RDGHACNHVTGKCTRCNAGWIGDRCETKC 92
Query: 1914 APGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLG 1973
+ G YG+ +C A +C + G CD +G C+C PGV G C+ P GL+ G
Sbjct: 93 SNGTYGE-----DC-AFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPP--GLH-GAD 143
Query: 1974 CT-PCNCGIASESTQCDDDNGQCRC----AKGVTG 2003
C C+C E T CD G C KGV G
Sbjct: 144 CAQACSC---HEDT-CDPVTGACHLETNQRKGVMG 174
Score = 72.9 bits (171), Expect = 2e-11
Identities = 56/177 (31%), Positives = 76/177 (42%), Gaps = 31/177 (17%)
Query: 1855 CAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-C 1913
C AG+YG+ C+ C G Q P C G CL C G C+ C
Sbjct: 2 CPAGFYGLG----------CRR-RC-GQCKGQQP--CTVAEGRCLTCEPGWNGTKCDQPC 47
Query: 1914 APGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCD-RCAPDHWGLNTG 1971
A GFYG+ S C C G A C+ TG C C G IG++C+ +C+ +G +
Sbjct: 48 ATGFYGEGC-SHRCPPC---RDGHA-CNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCA 102
Query: 1972 LGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCD-QCAAGFWNYTKDGCDHCNCN 2027
C C G CD +G+C C+ GV G C+ C G + D C+C+
Sbjct: 103 FVCADCGSG------HCDFQSGRCLCSPGVHGPHCNVTCPPGL--HGADCAQACSCH 151
Score = 67.7 bits (158), Expect = 7e-10
Identities = 52/152 (34%), Positives = 70/152 (46%), Gaps = 24/152 (15%)
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV-CRPGVIGEKCDR-CAPDHWGLNT 1970
C GFYG + C C G C G C+ C PG G KCD+ CA +G
Sbjct: 2 CPAGFYGLGC-RRRCGQCK----GQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGC 56
Query: 1971 GLGCTPCNCGIASESTQCDDDNGQC-RCAKGVTGKQCD-QCAAGFWNYTKDGCDHC-NCN 2027
C PC G A C+ G+C RC G G +C+ +C+ G Y +D C +C
Sbjct: 57 SHRCPPCRDGHA-----CNHVTGKCTRCNAGWIGDRCETKCSNG--TYGEDCAFVCADCG 109
Query: 2028 TGYSVGFMCN-ATGQCECLPGVIGEKCD-RCP 2057
+G+ C+ +G+C C PGV G C+ CP
Sbjct: 110 SGH-----CDFQSGRCLCSPGVHGPHCNVTCP 136
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/162 (31%), Positives = 66/162 (40%), Gaps = 25/162 (15%)
Query: 1352 CNTFGGQC-PCKPNVIGRTCSA-CRTGYYG---FPNCRPCHCPSTAICDDNGMCI-CPKN 1405
C G+C C+P G C C TG+YG C PC A G C C
Sbjct: 24 CTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCR-DGHACNHVTGKCTRCNAG 82
Query: 1406 VEGENCD-RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCD- 1463
G+ C+ +C T+ D C DC C+ SG+C C V G C+
Sbjct: 83 WIGDRCETKCSNGTYGEDCAFVCADCGSG---------HCDFQSGRCLCSPGVHGPHCNV 133
Query: 1464 HCVPGHYAFPDCYQ-CTCNRHGTTYDVCDQNTAQCYCKTNVR 1504
C PG + DC Q C+C+ D CD T C+ +TN R
Sbjct: 134 TCPPGLHG-ADCAQACSCHE-----DTCDPVTGACHLETNQR 169
Score = 64.1 bits (149), Expect = 9e-09
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 12/144 (8%)
Query: 418 CTPTDGLC-PCKYNYAGKSCEI-CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT-CKS 474
CT +G C C+ + G C+ C G+Y C + C + C+ +TG CT C +
Sbjct: 24 CTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSH-RCPPCRD-GHACNHVTGKCTRCNA 81
Query: 475 KYSGRTCN-QCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCD-QCLS 532
+ G C +C G Y C SG CD SG+C+C G GP C+ C
Sbjct: 82 GWIGDRCETKCSNGTYGEDCAFVCADCGSGH----CDFQSGRCLCSPGVHGPHCNVTCPP 137
Query: 533 GYYMQVLGRERQCVPCNCDP-TGS 555
G + + C CDP TG+
Sbjct: 138 GLHGADCAQACSCHEDTCDPVTGA 161
Score = 53.2 bits (122), Expect = 2e-05
Identities = 38/118 (32%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1738 CPRAYRGLSCEQ-CAEGHYRLP-SGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C + G C+Q CA G Y S C PC+ +GH+ C+ TG C C IGD CE
Sbjct: 34 CEPGWNGTKCDQPCATGFYGEGCSHRCPPCR-DGHA--CNHVTGKCTRCNAGWIGDRCET 90
Query: 1796 -CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARC 1852
C +G +G+ DC C + C +G + C PG GA C
Sbjct: 91 KCSNGTYGEDCAFVCADCGSGHCDF----QSGRCLCSPGVHGPHCNVTCPPGLHGADC 144
Score = 52.8 bits (121), Expect = 2e-05
Identities = 62/202 (30%), Positives = 75/202 (37%), Gaps = 45/202 (22%)
Query: 1750 CAEGHYRLPSGFCVPC-QCNGHSDQCDVNTGICLNCADNTIGDHCEF-CMSGYHGDATVG 1807
C G Y L G C QC G C V G CL C G C+ C +G++G+ G
Sbjct: 2 CPAGFYGL--GCRRRCGQCKGQQP-CTVAEGRCLTCEPGWNGTKCDQPCATGFYGE---G 55
Query: 1808 TPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCE-YCAAGYYGIPEDT 1866
C C + N+ C C G+ G RCE C+ G YG ED
Sbjct: 56 CSHRC--PPCRDGHACNHVTGKC----------TRCNAGWIGDRCETKCSNGTYG--EDC 101
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNL-CAPGFYGDAIFSK 1925
C C G CD +G CL C G CN+ C PG +G +
Sbjct: 102 AF----VCADCG---------SGHCDFQSGRCL-CSPGVHGPHCNVTCPPGLHG----AD 143
Query: 1926 NCTACICDEFGMADCDSTTGTC 1947
AC C E CD TG C
Sbjct: 144 CAQACSCHE---DTCDPVTGAC 162
Score = 46.8 bits (106), Expect = 0.001
Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 22/152 (14%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRC-EC 381
G+CL C+ G C++ T + YG+ C PC+ D H C +G+C C
Sbjct: 29 GRCLTCEPGWNGTKCDQPCATGF--YGEGCSHR--CPPCR-DGH----ACNHVTGKCTRC 79
Query: 382 RPEFQPPDC-SSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI-C 439
+ C + C+ G + + C HC G C C G C + C
Sbjct: 80 NAGWIGDRCETKCSNGTYG----EDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTC 135
Query: 440 EDGYYSPEC-KNCECNTVGSVSYVCDKLTGDC 470
G + +C + C C+ CD +TG C
Sbjct: 136 PPGLHGADCAQACSCH-----EDTCDPVTGAC 162
Score = 44.0 bits (99), Expect = 0.010
Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 18/110 (16%)
Query: 323 GKCLNCQHNTEGINCN-KCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCEC 381
GKC C G C KC YG+ D VC C +G+C+ +SGRC C
Sbjct: 74 GKCTRCNAGWIGDRCETKCSNG---TYGE--DCAFVCADC------GSGHCDFQSGRCLC 122
Query: 382 RPEFQPPDCS-SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYN 430
P P C+ +C G + C+C+ + C P G C + N
Sbjct: 123 SPGVHGPHCNVTCPPGLHGADCAQACSCH-----EDTCDPVTGACHLETN 167
Score = 41.5 bits (93), Expect = 0.056
Identities = 43/145 (29%), Positives = 54/145 (37%), Gaps = 17/145 (11%)
Query: 1373 CRTGYYGFPNCRPC-HCPSTAICD-DNGMCI-CPKNVEGENCDRCKPYTFNFDVQRGCDD 1429
C G+YG R C C C G C+ C G CD+ P F GC
Sbjct: 2 CPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQ--PCATGF-YGEGCSH 58
Query: 1430 CNCNPLGVVGNQLQCEADSGKCA-CRENVRGRVCD-HCVPGHYAFPDCYQCTCNRHGTTY 1487
C P + C +GKC C G C+ C G Y DC C G+ +
Sbjct: 59 -RCPPCR---DGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYG-EDC-AFVCADCGSGH 112
Query: 1488 DVCDQNTAQCYCKTNVRGQACD-TC 1511
CD + +C C V G C+ TC
Sbjct: 113 --CDFQSGRCLCSPGVHGPHCNVTC 135
Score = 37.1 bits (82), Expect = 1.2
Identities = 47/195 (24%), Positives = 64/195 (32%), Gaps = 41/195 (21%)
Query: 580 CSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CREQFYNYPACEEC 638
C G+Y C G T + C+ ++G KCD C FY C
Sbjct: 2 CPAGFYGLGCRRRCG-QCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRC 60
Query: 639 NCDPRG-----VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQC 693
G VT C + G+ C+ K G DC F C C
Sbjct: 61 PPCRDGHACNHVTGKCTRCNAGWIGDRCETKCS-NGTYGEDCA-----------FVCADC 108
Query: 694 NCNLAGTLNSLGACNTKSGQCVCKQHVGERQCD-QCLDGFYRLQTNDVFGCTE-CDCDIG 751
G C+ +SG+C+C V C+ C G + C + C C
Sbjct: 109 GS---------GHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD------CAQACSCH-- 151
Query: 752 GSIDNNCDKTTGQCH 766
++ CD TG CH
Sbjct: 152 ---EDTCDPVTGACH 163
Score = 34.7 bits (76), Expect = 6.4
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 11/74 (14%)
Query: 706 ACNTKSGQCV-CKQH-VGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTG 763
ACN +G+C C +G+R +C +G Y + F C +C GS +CD +G
Sbjct: 68 ACNHVTGKCTRCNAGWIGDRCETKCSNGTYG--EDCAFVCADC-----GS--GHCDFQSG 118
Query: 764 QCHCHSRVEGRRCD 777
+C C V G C+
Sbjct: 119 RCLCSPGVHGPHCN 132
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 472
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 473 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 528
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 235
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 236 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 284
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 342
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 343 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 402 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 457
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 458 CQNDASCRDLVNGYRCICP 476
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 888
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 355 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 467
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 468 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 522
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 220 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 276
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 277 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 75.8 bits (178), Expect = 3e-12
Identities = 92/359 (25%), Positives = 129/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ PEC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 72.5 bits (170), Expect = 3e-11
Identities = 116/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C + G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLNGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LNGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 61.3 bits (142), Expect = 6e-08
Identities = 94/394 (23%), Positives = 133/394 (33%), Gaps = 61/394 (15%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ P C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L +
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR 472
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFY-RLQTNDVFG 742
P G +C + C G C+ + QC C GF L D+
Sbjct: 473 CICPPGYAGDHCERDIDECASNPC-LNGGH--CQNEINRFQC-LCPTGFSGNLCQLDIDY 528
Query: 743 CTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
C C G N C C EG+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 58.8 bits (136), Expect = 3e-07
Identities = 80/319 (25%), Positives = 109/319 (34%), Gaps = 52/319 (16%)
Query: 484 CQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRER 543
C YY + K C CD +G C G+ GP C++ + R
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAIC----------R 235
Query: 544 QCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLS--CN----CDV 597
Q C P SC G C C + G CD+C P +P C+ CN C
Sbjct: 236 Q----GCSPKHG---SCKLPGDCRCQYGWQGLYCDKCIP----HPGCVHGICNEPWQCLC 284
Query: 598 SGSIGSTCDDNGLCHCKSN---FDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGS 654
+ G D L +C ++ +G C Y +C E P A A C S
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHA-CLS 342
Query: 655 VPAGELCQCKDRVQGRICNDCKPLYWN-LQEYNPFGCEQCNCNLAGTLNSL-----GACN 708
P CK+ G C +C P + N C NC+ GT L C
Sbjct: 343 DPCHNRGSCKETSLGFEC-ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401
Query: 709 TKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCD----KTTGQ 764
+ C+ E + C++ ++ CDC + G + NCD GQ
Sbjct: 402 PQWTGKTCQLDANECEAKPCVNA---KSCKNLIASYYCDC-LPGWMGQNCDININDCLGQ 457
Query: 765 CH----CHSRVEGRRCDQP 779
C C V G RC P
Sbjct: 458 CQNDASCRDLVNGYRCICP 476
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 888
Score = 46.4 bits (105), Expect = 0.002
Identities = 48/178 (26%), Positives = 66/178 (37%), Gaps = 33/178 (18%)
Query: 1354 TFGGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD--NGM-CICPKNVEGEN 1410
+ G +C C P G TCS +C P +C C D NG C+CP G+
Sbjct: 355 SLGFECECSPGWTGPTCST------NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 1411 C----DRC--KPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADS--GKC----ACREN 1456
C + C KP + C+C P G +G + G+C +CR+
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLP-GWMGQNCDININDCLGQCQNDASCRDL 467
Query: 1457 VRGRVCDHCVPGHYA------FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQAC 1508
V G C C PG+ +C C G + + N QC C T G C
Sbjct: 468 VNGYRC-ICPPGYAGDHCERDIDECASNPCLNGGHCQN--EINRFQCLCPTGFSGNLC 522
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LNGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 39.9 bits (89), Expect = 0.17
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 1373 CRTGYYGFPNCRPCHC-----PSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGC 1427
C G+ G P C C P C G C C +G CD+C P+ V C
Sbjct: 220 CMEGWMG-PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHP--GCVHGIC 276
Query: 1428 DD---CNCNPLGVVGNQLQCEADSGKCACREN-VRGRVCDHCVPGHY--AFPDCY---QC 1478
++ C C G QL C+ D C + + G C + P Y + P+ Y C
Sbjct: 277 NEPWQCLCETNW--GGQL-CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Query: 1479 TCNRHGTTYDVCDQNTA--------QCYCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
H D C + +C C G C T N+ D +P+ C+
Sbjct: 334 EIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 76.6 bits (180), Expect = 2e-12
Identities = 109/416 (26%), Positives = 149/416 (35%), Gaps = 80/416 (19%)
Query: 228 GGRCMCNGHADTCE-PADPAGNLNIL-VCRCQHNTC--GPQCNKCCSGFEQKKWRISQNW 283
GG C + C P +GNL L + C+ N C G QC S + K +++
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK---CPEDY 555
Query: 284 DRFSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPT 343
+ +C H TT C ID +++ N EG I+ N C P
Sbjct: 556 EGKNCSHLKDHCRTTPCEV---IDSCTVAMASNDTPEG----------VRYISSNVCGP- 601
Query: 344 YYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNC 403
+GK + C C+ F+ C E CE P C D N
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC-------IDGVNS 650
Query: 404 KPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYV 462
C C+ +G EG +C C + G +C + +Y +CKN + T S
Sbjct: 651 YKCICS-DGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC-DCKNGWKGKTCHSRDSQ 708
Query: 463 CDKLT----------GD---CTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSIC 509
CD+ T GD C C + G TCN + +C P C GT +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS-----SCLPNPCHNGGT--CVV 761
Query: 510 DDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCL 569
+ S C+CK G+ GP C Q C P C +G T +C C
Sbjct: 762 NGESFTCVCKEGWEGPICAQ-----------NTNDCSPHPCYNSG-TCVDGDNWYRCECA 809
Query: 570 TNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKC 622
F G C +C S C + G+TC D NG C C GAKC
Sbjct: 810 PGFAGPDC------RININECQSSPC----AFGATCVDEINGYRCVCPPGHSGAKC 855
Score = 74.5 bits (175), Expect = 6e-12
Identities = 117/483 (24%), Positives = 175/483 (36%), Gaps = 88/483 (18%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVC-QPCQCDPHFSTGNCEEESGRCEC 381
G C CQ+ +G+ C+KC P +G +C +P QC CE G C
Sbjct: 249 GDC-RCQYGWQGLYCDKCIPHPGCVHG-------ICNEPWQC-------LCETNWGGQLC 293
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
D + C +PC LNG + P C C Y+G +CEI E
Sbjct: 294 -----DKDLNYCG-------THQPC---LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH 338
Query: 442 GYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDT 501
C + C+ GS L +C C ++G TC+ N C P NC
Sbjct: 339 A-----CLSDPCHNRGSCKET--SLGFECECSPGWTGPTCST------NIDDCSPNNCSH 385
Query: 502 SGTEPSICDD-VSG-QCICKAGFGGPRCD---------QCLSGYYMQ--VLGRERQCVP- 547
GT C D V+G +C+C + G C C++ + + C+P
Sbjct: 386 GGT----CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 548 ---CNCD-PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGS 603
NCD C D C L N G +C C PGY C D+ +
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVN--GYRC-ICPPGYAGD----HCERDIDECASN 494
Query: 604 TCDDNGLCHCKSNFDGAKCDTCREQFY-NYPACEECNCDPRGVTASFAGCGSVPAGELCQ 662
C D G HC++ + +C C F N + C+P + A C + + C+
Sbjct: 495 PCLDGG--HCQNEINRFQC-LCPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCK 550
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQC----VCKQ 718
C + +G+ C+ K + + + C +A G S C CK
Sbjct: 551 CPEDYEGKNCSHLKD---HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 719 HVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
G + C GF ++ + C C GG+ + + + +C C EG C+
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN--SYKCICSDGWEGAYCE 665
Query: 778 QPI 780
I
Sbjct: 666 TNI 668
Score = 72.1 bits (169), Expect = 3e-11
Identities = 91/359 (25%), Positives = 128/359 (35%), Gaps = 69/359 (19%)
Query: 439 CEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCN 498
C +G+ EC C S + KL GDC C+ + G C++C +P C
Sbjct: 220 CMEGWMGRECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC----IPHPGCVHGI 275
Query: 499 CDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTST 558
C+ EP QC+C+ +GG CD+ L+ G + C+ G T +
Sbjct: 276 CN----EP-------WQCLCETNWGGQLCDKDLN-----YCGTHQPCL------NGGTCS 313
Query: 559 SCSADG-KCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGL---CHCK 614
+ D +C+C + G C+ CLS C GS C + L C C
Sbjct: 314 NTGPDKYQCSCPEGYSGPNCEIAEHA------CLSDPCHNRGS----CKETSLGFECECS 363
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRIC-- 672
+ G C T N C NC G C + G C C + G+ C
Sbjct: 364 PGWTGPTCST------NIDDCSPNNCSHGGT------CQDLVNGFKCVCPPQWTGKTCQL 411
Query: 673 --NDC--KPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKS--GQC----VCKQHVGE 722
N+C KP N C+C L G + N GQC C+ V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDC-LPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 723 RQCDQCLDGFYRLQ-TNDVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
+C C G+ D+ C C GG N ++ QC C + G C I
Sbjct: 471 YRC-ICPPGYAGDHCERDIDECASNPCLDGGHCQNEINRF--QCLCPTGFSGNLCQLDI 526
Score = 66.1 bits (154), Expect = 2e-09
Identities = 103/376 (27%), Positives = 147/376 (39%), Gaps = 75/376 (19%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFC-VPCQCNGHSDQCDVNTGICLNCAD-NTIGDH 1792
+C+C ++GL C++C H G C P QC C+ N G L D N G H
Sbjct: 250 DCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC-----LCETNWGGQLCDKDLNYCGTH 303
Query: 1793 CEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS-CN----CQPGY 1847
+ C++G G + T D C+CP Y N C+++E+ L C+ C+
Sbjct: 304 -QPCLNG--GTCS-NTGPDKYQCSCPEGYSGPN----CEIAEHACLSDPCHNRGSCKETS 355
Query: 1848 GGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGN------IN-------PQDPG-SCDS 1893
G CE C+ G+ G T++ D C P NCS +N PQ G +C
Sbjct: 356 LGFECE-CSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1894 INGDC--LKCVNNTAGAACNLCAPGFYGDAI---FSKNCTACICDEFGM----ADC-DST 1943
+C CVN A + NL A +Y D + +NC I D G A C D
Sbjct: 412 DANECEAKPCVN--AKSCKNLIA-SYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 1944 TG-TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVT 2002
G C+C PG G+ C+R + PC + Q + + QC C G +
Sbjct: 469 NGYRCICPPGYAGDHCERDIDE-------CASNPC---LDGGHCQNEINRFQCLCPTGFS 518
Query: 2003 GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPERWVL 2062
G C D C+ C G + + C+C G+ C +
Sbjct: 519 GNLC--------QLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 2063 IPQEGCLECDSCTDAL 2078
P C DSCT A+
Sbjct: 570 TP---CEVIDSCTVAM 582
Score = 57.6 bits (133), Expect = 8e-07
Identities = 95/398 (23%), Positives = 133/398 (33%), Gaps = 69/398 (17%)
Query: 392 SCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNC 451
+C G+ C C + G C C+Y + G C+ C P C +
Sbjct: 219 TCMEGWMGR-ECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKC---IPHPGCVHG 274
Query: 452 ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDD 511
CN C C++ + G+ C++ Y T +PC GT + D
Sbjct: 275 ICNE-----------PWQCLCETNWGGQLCDK-DLNYCG--THQPCL--NGGTCSNTGPD 318
Query: 512 VSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTN 571
QC C G+ GP C+ E C+ C GS + S +C C
Sbjct: 319 -KYQCSCPEGYSGPNCEIA-----------EHACLSDPCHNRGSCKET-SLGFECECSPG 365
Query: 572 FGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD--NGL-CHCKSNFDGAKCDTCREQ 628
+ G C DC NC S G TC D NG C C + G C +
Sbjct: 366 WTGPTCST------NIDDCSPNNC----SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 629 FYNYPACEECNCDPRGVTASFAGCGSVPA--GELCQCK-DRVQGRICND--CKPLYWNLQ 683
P +C + + AS+ C +P G+ C + G+ ND C+ L
Sbjct: 416 CEAKPCVNAKSC--KNLIASYY-CDCLPGWMGQNCDININDCLGQCQNDASCRDL----- 467
Query: 684 EYNPFGCEQCNCNLAGTLNSLGACNTKSGQCV----CKQHVGERQCDQCLDGFY-RLQTN 738
N + C C AG S C+ C+ + QC C GF L
Sbjct: 468 -VNGYRC-ICPPGYAGDHCERDIDECASNPCLDGGHCQNEINRFQC-LCPTGFSGNLCQL 524
Query: 739 DVFGCTECDCDIGGSIDNNCDKTTGQCHCHSRVEGRRC 776
D+ C C G N C C EG+ C
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYF--CKCPEDYEGKNC 560
Score = 50.8 bits (116), Expect = 9e-05
Identities = 51/179 (28%), Positives = 66/179 (36%), Gaps = 35/179 (19%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYG------FPNCRPCHCPSTAICDDNG---MCICPKNV 1406
GG C N I R C TG+ G C P C + A C + C CP++
Sbjct: 499 GGHCQ---NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1407 EGENCDRCKPY--TFNFDVQRGCD---DCNCNPLG-------VVGNQLQCEADSG---KC 1451
EG+NC K + T +V C N P G V G +C++ SG C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 1452 ACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
C + G C H DC C GT D N+ +C C G C+T
Sbjct: 616 DCNKGFTGTYC------HENINDCESNPCRNGGTCID--GVNSYKCICSDGWEGAYCET 666
Score = 48.4 bits (110), Expect = 5e-04
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 57/347 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+CP Y G +C + P C S+ D G+ + N G H +
Sbjct: 549 CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--DTPEGVRY-ISSNVCGPHGK- 604
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLIS------CNCQPGYGG 1849
C S G T + C + + N S G+ I C C G+ G
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYC---HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1850 ARCEYCAAGYYGIPEDTDLHTGDYCKP------CNCSGNINPQDPGSCDSINGDCLKCVN 1903
A YC ++ H G C+ C+C N +C S + C +
Sbjct: 662 A---YCETNINDCSQNP-CHNGGTCRDLVNDFYCDCK---NGWKGKTCHSRDSQCDEATC 714
Query: 1904 NTAGAACN-------LCAPGFYGDAIFSKNCTACI---CDEFGMADCDSTTGTCVCRPGV 1953
N G + +C G+ G ++C+ C G + + TCVC+ G
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 1954 IGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNG-QCRCAKGVTGKQCDQCAAG 2012
G C + D C+P C + T D DN +C CA G G C
Sbjct: 775 EGPICAQNTND---------CSPHPC--YNSGTCVDGDNWYRCECAPGFAGPDC------ 817
Query: 2013 FWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDRCPER 2059
+ C C G + N +C C PG G KC R
Sbjct: 818 --RININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVSGR 861
Score = 48.4 bits (110), Expect = 5e-04
Identities = 71/288 (24%), Positives = 95/288 (32%), Gaps = 47/288 (16%)
Query: 1732 SVEECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN---CADNT 1788
++ +C+ G +C + + S C + + C N C N C D
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP--CHNGGTCRDLV 686
Query: 1789 IGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYG 1848
+C+ C +G+ G C C NN D G C C G+
Sbjct: 687 NDFYCD-CKNGWKGKTCHSRDSQCDEATC------NNGGTCYD---EGDAFKCMCPGGWE 736
Query: 1849 GARCEYCAAGYYGIPEDTDLHTGDYCK------PCNCS----GNINPQDPGSCDSINGDC 1898
G C A +P H G C C C G I Q+ C C
Sbjct: 737 GTTCNI-ARNSSCLPNPC--HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP--HPC 791
Query: 1899 LK---CVNNTAGAACNLCAPGFYG-DAIFSKN-CTACICDEFGMADCDSTTG-TCVCRPG 1952
CV+ C CAPGF G D + N C + C FG D G CVC PG
Sbjct: 792 YNSGTCVDGDNWYRCE-CAPGFAGPDCRININECQSSPC-AFGATCVDEINGYRCVCPPG 849
Query: 1953 VIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKG 2000
G KC +G C + + + DDD C+C G
Sbjct: 850 HSGAKCQEV--------SGRPCITMG-SVIPDGAKWDDDCNTCQCLNG 888
Score = 45.2 bits (102), Expect = 0.005
Identities = 75/330 (22%), Positives = 105/330 (31%), Gaps = 33/330 (10%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCE 1794
+C CP + G +C+ A P C+ S CD G D I D
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD--- 453
Query: 1795 FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCD-LSENGSLISCNCQPGYGGARCE 1853
C+ DA+ + C CP Y ++ D + N L +CQ +C
Sbjct: 454 -CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLDGGHCQNEINRFQC- 511
Query: 1854 YCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL-KCVNNTAGAACNL 1912
C G+ G D+ DYC+P C Q+ C + D KC + G C+
Sbjct: 512 LCPTGFSGNLCQLDI---DYCEPNPC------QNGAQCYNRASDYFCKCPEDYEGKNCS- 561
Query: 1913 CAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGL 1972
D + C MA D+ G V G +C G T
Sbjct: 562 ----HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH-GKCKSQSGGKFT-- 614
Query: 1973 GCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSV 2032
C+C T C ++ C G C + DG + C T +
Sbjct: 615 ----CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 2033 GFM--CNATGQCECLPGVIGEKCDRCPERW 2060
C+ G C L V CD C W
Sbjct: 671 CSQNPCHNGGTCRDL--VNDFYCD-CKNGW 697
Score = 45.2 bits (102), Expect = 0.005
Identities = 88/403 (21%), Positives = 139/403 (34%), Gaps = 69/403 (17%)
Query: 232 MCNGHADTCEPADPAGNLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEPC 291
+C D CEP +P N +C + C KC +E K S D PC
Sbjct: 521 LCQLDIDYCEP-NPCQN----GAQCYNRASDYFC-KCPEDYEGKN--CSHLKDHCRTTPC 572
Query: 292 NCHNHTTECTYDPEIDE--KRLSLDINGRY-----EGGGK-CLNCQHNTEGINC----NK 339
+ T + E + +S ++ G + + GGK +C G C N
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYF- 398
C R G D ++ + C C + CE C P C ++
Sbjct: 633 CESNPCRNGGTCIDGVNSYK-CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 399 DYPN-CKPCTCNLNGTEGEHCTPTDG----------LCPCKYNYAGKSCEICEDGYYSPE 447
D N K TC+ ++ + T +G C C + G +C I + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 448 -CKNCECNTVGSVSY-----------VCDKLTGDCTCKSKYSGRTCN--------QCQAG 487
C N V S+ +C + T DC+ Y+ TC +C G
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Query: 488 YYNYPTCK----PCNCDTSGTEPSICDDVSG-QCICKAGFGGPRCDQCLSGYYMQVLGR- 541
+ P C+ C + D+++G +C+C G G +C + +SG +G
Sbjct: 812 FAG-PDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE-VSGRPCITMGSV 869
Query: 542 -------ERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
+ C C C G + S G CL + G ++C
Sbjct: 870 IPDGAKWDDDCNTCQC-LNGRIACSKVWCGPRPCLLHKGHSEC 911
Score = 44.8 bits (101), Expect = 0.006
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 30/176 (17%)
Query: 1346 GSTELECNTFGGQCPCKPNVIGR-TCSACR--TGYYGFPNCRPCH---CPSTAICDD--- 1396
G + N G CK G+ TC + TG Y N C C + C D
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 1397 NGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACREN 1456
+ CIC EG C+ +DC+ NP G D C C+
Sbjct: 650 SYKCICSDGWEGAYCET------------NINDCSQNPCHNGGTCRDLVNDF-YCDCKNG 696
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
+G+ C H C + TCN GT YD + + +C C G C+ +
Sbjct: 697 WKGKTC------HSRDSQCDEATCNNGGTCYD--EGDAFKCMCPGGWEGTTCNIAR 744
Score = 44.4 bits (100), Expect = 0.008
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 50/210 (23%)
Query: 1340 CLC--DFMGSTELECNTFGGQCPCKPNVIGRTCSACRTGYY-----GF--PNC----RPC 1386
C+C + G T C +C KP V ++C YY G+ NC C
Sbjct: 398 CVCPPQWTGKT---CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 1387 --HCPSTAICDD--NGM-CICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQ 1441
C + A C D NG CICP G++C+R D+ D+C NP + G
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCER--------DI----DECASNPC-LDGGH 501
Query: 1442 LQCEADSGKCACRENVRGRVC----DHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQC 1497
Q E + +C C G +C D+C P P C + Y C
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPN----PCQNGAQCYNRASDY--------FC 549
Query: 1498 YCKTNVRGQACDTCKEEYFNLQDDNPDGCT 1527
C + G+ C K+ + D CT
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Score = 40.7 bits (91), Expect = 0.097
Identities = 53/204 (25%), Positives = 73/204 (35%), Gaps = 43/204 (21%)
Query: 1343 DFMGSTELECNTFGGQCPCKPNVIGRTCSA--CRTGYYGFPNCRPCHCPSTAICDDNGMC 1400
DF G + N G C +GR C+ CR G C P H C G C
Sbjct: 205 DFFGHYACDQN---GNKTCMEGWMGRECNRAICRQG------CSPKH----GSCKLPGDC 251
Query: 1401 ICPKNVEGENCDRCKPYTFNFDVQRGCDD---CNCNPLGVVGNQLQCEADSGKCACREN- 1456
C +G CD+C P+ V C++ C C G QL C+ D C +
Sbjct: 252 RCQYGWQGLYCDKCIPHP--GCVHGICNEPWQCLCETNW--GGQL-CDKDLNYCGTHQPC 306
Query: 1457 VRGRVCDHCVPGHY--AFPDCY---QCTCNRHGTTYDVCDQNTA--------QCYCKTNV 1503
+ G C + P Y + P+ Y C H D C + +C C
Sbjct: 307 LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW 366
Query: 1504 RGQACDTCKEEYFNLQDDNPDGCT 1527
G C T N+ D +P+ C+
Sbjct: 367 TGPTCST------NIDDCSPNNCS 384
Score = 37.5 bits (83), Expect = 0.90
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 1945 GTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTP--CNCGIASESTQCDDDNGQC----RCA 1998
G C C+ G G CD+C P H G G+ P C C CD D C C
Sbjct: 249 GDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1999 KGVTGK-------QCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATG---QCECLPG 2047
G T QC C G+ + +H C + ++ G C T +CEC PG
Sbjct: 308 NGGTCSNTGPDKYQC-SCPEGYSGPNCEIAEHACLSDPCHNRG-SCKETSLGFECECSPG 365
Query: 2048 VIGEKC 2053
G C
Sbjct: 366 WTGPTC 371
Score = 35.9 bits (79), Expect = 2.8
Identities = 46/196 (23%), Positives = 72/196 (36%), Gaps = 31/196 (15%)
Query: 1356 GGQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD---NGMCICPKNVEGENCD 1412
G +C C P G+TC C C + C + + C C G+NCD
Sbjct: 395 GFKCVCPPQWTGKTCQLDAN------ECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCD 448
Query: 1413 --------RCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDH 1464
+C+ D+ G C C P G G+ CE D +CA + G C +
Sbjct: 449 ININDCLGQCQNDASCRDLVNGY-RCICPP-GYAGD--HCERDIDECASNPCLDGGHCQN 504
Query: 1465 CVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPD 1524
+ + +QC C G + ++C + C G C +YF ++ +
Sbjct: 505 EI-------NRFQCLCPT-GFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Query: 1525 G--CTKCFCFGKTTRC 1538
G C+ +TT C
Sbjct: 557 GKNCSHLKDHCRTTPC 572
>AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein.
Length = 2450
Score = 76.6 bits (180), Expect = 2e-12
Identities = 79/271 (29%), Positives = 104/271 (38%), Gaps = 64/271 (23%)
Query: 365 PHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGL 424
P GN E SG C C P F PDCS A C P C+ NG + G
Sbjct: 270 PRNCHGNGECVSGTCHCFPGFLGPDCSRAA--------C-PVLCSGNGQYSK------GR 314
Query: 425 CPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQC 484
C C + G C++ + +C + +C G +C + G C C S Y G +C +
Sbjct: 315 CLCFSGWKGTECDV-----PTTQCIDPQCGGRG----IC--IMGSCACNSGYKGESCEEA 363
Query: 485 QAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC--------DQCLS-GYY 535
C C G +C + G+C C G+GG C DQC G Y
Sbjct: 364 D--------CIDPGCSNHG----VC--IHGECHCSPGWGGSNCEILKTMCPDQCSGHGTY 409
Query: 536 MQVLGRERQCVPCNCDP--TGSTSTS--CSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
+Q G C CDP TG ++ CS D C G C +C G + P C
Sbjct: 410 LQESG------SCTCDPNWTGPDCSNEICSVD--CGSHGVCMGGTC-RCEEG-WTGPACN 459
Query: 592 SCNCDVSGSIGSTCDDNGLCHCKSNFDGAKC 622
C + TC D G C C ++G C
Sbjct: 460 QRACHPRCAEHGTCKD-GKCECSQGWNGEHC 489
Score = 53.6 bits (123), Expect = 1e-05
Identities = 46/167 (27%), Positives = 67/167 (40%), Gaps = 20/167 (11%)
Query: 1920 DAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCA-PDHWGLNTGLGCTPCN 1978
+ I ++ C + G +C S GTC C PG +G C R A P N C
Sbjct: 259 NTIVIESVVECPRNCHGNGECVS--GTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCL 316
Query: 1979 CGIASESTQCDDDNGQC---RC-AKGVTGKQCDQCAAGFWNYTKDGCDHCNC-NTGYSVG 2033
C + T+CD QC +C +G+ C +G Y + C+ +C + G S
Sbjct: 317 CFSGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSG---YKGESCEEADCIDPGCSNH 373
Query: 2034 FMCNATGQCECLPGVIGEKC--------DRCPERWVLIPQEGCLECD 2072
+C G+C C PG G C D+C + + G CD
Sbjct: 374 GVC-IHGECHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCD 419
Score = 53.6 bits (123), Expect = 1e-05
Identities = 69/261 (26%), Positives = 99/261 (37%), Gaps = 56/261 (21%)
Query: 1736 CQCPRAYRGLSCEQCA-----EGHYRLPSGFCVPCQCNGHSDQCDVNTGICLN--CADN- 1787
C C + G C + A G+ + G C+ C +CDV T C++ C
Sbjct: 284 CHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCL-CFSGWKGTECDVPTTQCIDPQCGGRG 342
Query: 1788 -TIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPG 1846
I C C SGY G++ DC+ C SN+ C E C+C PG
Sbjct: 343 ICIMGSCA-CNSGYKGESC--EEADCIDPGC-----SNHGV--CIHGE------CHCSPG 386
Query: 1847 YGGARCE----YC---AAGYYGIPEDTDLHTGD--YCKPCNCSGNINPQDPGSCDSINGD 1897
+GG+ CE C +G+ +++ T D + P +CS I D GS G
Sbjct: 387 WGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGP-DCSNEICSVDCGSHGVCMGG 445
Query: 1898 CLKCVNNTAGAACNL-------------------CAPGFYGDAIFSKNCTACICDEFGMA 1938
+C G ACN C+ G+ G+ + C +C+ G
Sbjct: 446 TCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPG-LCNSNGRC 504
Query: 1939 DCDSTTGTCVCRPGVIGEKCD 1959
D CVC+PG G CD
Sbjct: 505 TLDQNGWHCVCQPGWRGAGCD 525
Score = 49.6 bits (113), Expect = 2e-04
Identities = 55/208 (26%), Positives = 70/208 (33%), Gaps = 25/208 (12%)
Query: 1334 NSGARPCLCDFMGSTELECNTFG----GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCP 1389
NSG + C+ + C+ G G+C C P G C +T C P C
Sbjct: 352 NSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWGGSNCEILKT------MC-PDQCS 404
Query: 1390 STAI-CDDNGMCICPKNVEGENCDR--CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEA 1446
++G C C N G +C C + V G C C G G A
Sbjct: 405 GHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG-GTCRCEE-GWTGPACNQRA 462
Query: 1447 DSGKCACRENVRGRVCDHCVPG----HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTN 1502
+CA + C+ C G H C CN +G DQN C C+
Sbjct: 463 CHPRCAEHGTCKDGKCE-CSQGWNGEHCTIEGC-PGLCNSNGRC--TLDQNGWHCVCQPG 518
Query: 1503 VRGQACDTCKEEYFNLQDDNP-DGCTKC 1529
RG CD E DN DG C
Sbjct: 519 WRGAGCDVAMETLCTDSKDNEGDGLIDC 546
Score = 42.7 bits (96), Expect = 0.024
Identities = 45/164 (27%), Positives = 59/164 (35%), Gaps = 44/164 (26%)
Query: 1358 QCP--CKPN--VIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGM-----CICPKNVEG 1408
+CP C N + TC C G+ G P+C CP +C NG C+C +G
Sbjct: 268 ECPRNCHGNGECVSGTCH-CFPGFLG-PDCSRAACP--VLCSGNGQYSKGRCLCFSGWKG 323
Query: 1409 ENCDRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPG 1468
CD P T C D C G+ G CAC +G C+
Sbjct: 324 TECD--VPTT-------QCIDPQCGGRGI--------CIMGSCACNSGYKGESCEEA--- 363
Query: 1469 HYAFPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCK 1512
DC C+ HG VC +C+C G C+ K
Sbjct: 364 -----DCIDPGCSNHG----VCIH--GECHCSPGWGGSNCEILK 396
Score = 42.3 bits (95), Expect = 0.032
Identities = 61/239 (25%), Positives = 83/239 (34%), Gaps = 35/239 (14%)
Query: 1835 NGSLIS--CNCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKP-CNCSGNINPQDPGSC 1891
NG +S C+C PG+ G C A G Y K C C + C
Sbjct: 276 NGECVSGTCHCFPGFLGPDCSRAACPVLCSGN------GQYSKGRCLCFSGWKGTE---C 326
Query: 1892 DSINGDCLKCVNNTAG----AACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTC 1947
D C+ G +C C G+ G++ +C C G+ G C
Sbjct: 327 DVPTTQCIDPQCGGRGICIMGSC-ACNSGYKGESCEEADCIDPGCSNHGVC----IHGEC 381
Query: 1948 VCRPGVIGEKCD----RCAPDHWGLNTGLGCT-PCNCGIASESTQCDDDNGQCRCAK-GV 2001
C PG G C+ C G T L + C C C ++ C GV
Sbjct: 382 HCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGV 441
Query: 2002 T-GKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKC--DRCP 2057
G C +C G +T C+ C+ + C G+CEC G GE C + CP
Sbjct: 442 CMGGTC-RCEEG---WTGPACNQRACHPRCAEHGTCK-DGKCECSQGWNGEHCTIEGCP 495
Score = 41.1 bits (92), Expect = 0.073
Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 22/139 (15%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEE------- 375
G+C +C G NC + L C CDP+++ +C E
Sbjct: 379 GEC-HCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCG 437
Query: 376 ------SGRCECRPEFQPPDCS--SCAYGYFDYPNCK--PCTCNLNGTEGEHCTPTDGLC 425
G C C + P C+ +C ++ CK C C+ G GEHCT +G C
Sbjct: 438 SHGVCMGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECS-QGWNGEHCT-IEG-C 494
Query: 426 PCKYNYAGKSCEICEDGYY 444
P N G+ C + ++G++
Sbjct: 495 PGLCNSNGR-CTLDQNGWH 512
>AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein.
Length = 2551
Score = 75.4 bits (177), Expect = 4e-12
Identities = 65/240 (27%), Positives = 94/240 (39%), Gaps = 39/240 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + G +CE C EG Y + C +G +Q + G C +C G HC+
Sbjct: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSC-VHGRCNQGPLGDGSC-DCDVGWRGVHCDN 1429
Query: 1796 CMSGYHGDATVGTPRDCLI-------CACPMPYPSNNFAL----SCDLSENGSLISCNCQ 1844
+ + + T T +CL C C + N +C++S G +C+
Sbjct: 1430 ATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 1489
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP--QDPGSCDSINGDCLKCV 1902
G R C AGY G G C INP ++ G CD N +C +
Sbjct: 1490 RTTPGRRVCTCKAGYTG--------DGIVCL------EINPCLENHGGCDK-NAECTQTG 1534
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACI-----CDEFGMAD-CDSTTGTCVCRPGVIGE 1956
N AACN C P + GD C+ C EF + + TC C+P IG+
Sbjct: 1535 PNQ--AACN-CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGD 1591
Score = 69.7 bits (163), Expect = 2e-10
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 529 QCLSGYYMQVLGRERQCVP----CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
+C GY+ GR+ Q P C+ G SA G+C C T F G C+ C PG
Sbjct: 1949 RCCKGYF----GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 585 YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT 624
+ PDCL C C G +G C C++ + G CDT
Sbjct: 2005 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 2043
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/99 (37%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 1414 CKPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYA 1471
CK Y F D Q G D CN GV +Q +G+C C G C+ C PG +
Sbjct: 1951 CKGY-FGRDCQACPGGPDAPCNNRGVCLDQYSA---TGECKCNTGFNGTACEMCWPGRFG 2006
Query: 1472 FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
PDC C C+ HG D + QC C+T G +CDT
Sbjct: 2007 -PDCLPCGCSDHGQCDDGI-TGSGQCLCETGWTGPSCDT 2043
Score = 64.9 bits (151), Expect = 5e-09
Identities = 44/140 (31%), Positives = 55/140 (39%), Gaps = 14/140 (10%)
Query: 518 CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
C G GP C +C G G PCN GS + +G C+C FGG C
Sbjct: 100 CCPGRWGPDCIECPGG-----AGS-----PCN--GRGSCAEGMEGNGTCSCQEGFGGTAC 147
Query: 578 DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE 636
+ C+ P C S CNC V G S D +G C C S + G KCD + E
Sbjct: 148 ETCADDNLFGPSCSSVCNC-VHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPE 206
Query: 637 ECNCDPRGVTASFAGCGSVP 656
C P + C +P
Sbjct: 207 NSRCSPSTEDENKLECKCLP 226
Score = 64.9 bits (151), Expect = 5e-09
Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 50/246 (20%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPED---TDLHTGDYCKP-----CNCS---GNI 1883
NG+ + C C G+ G CE C G YGI D + +H P C+C +
Sbjct: 1367 NGTGV-CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGV 1425
Query: 1884 NPQDPGSCDSINGDC---LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG---M 1937
+ + + D+ NG C C+ N+ G A CA GF G+ AC G
Sbjct: 1426 HCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAK 1485
Query: 1938 ADCDSTT---GTCVCRPGVIGE-----KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
ADC TT C C+ G G+ + + C +H G C +E TQ
Sbjct: 1486 ADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGG-----------CDKNAECTQTG 1534
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ----CECL 2045
+ C C TG C TK+G G S +CN TGQ C C
Sbjct: 1535 PNQAACNCLPAYTG-DGKVCTLINVCLTKNG--------GCSEFAICNHTGQVERTCTCK 1585
Query: 2046 PGVIGE 2051
P IG+
Sbjct: 1586 PNYIGD 1591
Score = 64.5 bits (150), Expect = 7e-09
Identities = 78/272 (28%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 483 QCQAGYYNYPTCKPC--NCDTSGTEPSIC-DDVSGQ--CICKAGFGGPRCDQCLSGYYMQ 537
+C AG++ P C+PC N IC D V+G C C GF G C+ C G Y
Sbjct: 1335 ECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
Query: 538 VLGRERQCV--PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
+ CV CN P G DG C+C + G CD + D + C
Sbjct: 1394 HCDQACSCVHGRCNQGPLG--------DGSCDCDVGWRGVHCDNATT-----EDNCNGTC 1440
Query: 596 DVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC-GS 654
S + + D C C + F G C ACE N G ++ A C +
Sbjct: 1441 HTSANCLTNSDGTASCKCAAGFQG-NGTICTA----INACEISN----GGCSAKADCKRT 1491
Query: 655 VPAGELCQCKDRV--QGRICNDCKPLYWN------LQEYNPFGCEQ--CNCNLAGT---- 700
P +C CK G +C + P N E G Q CNC A T
Sbjct: 1492 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGK 1551
Query: 701 -LNSLGACNTKSGQC----VCKQHVG--ERQC 725
+ C TK+G C +C H G ER C
Sbjct: 1552 VCTLINVCLTKNGGCSEFAIC-NHTGQVERTC 1582
Score = 63.7 bits (148), Expect = 1e-08
Identities = 60/195 (30%), Positives = 76/195 (38%), Gaps = 42/195 (21%)
Query: 1913 CAPGFYGDAIFSKNCTACI------CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDH 1965
C G++G ++C AC C+ G+ D S TG C C G G C+ C P
Sbjct: 1950 CCKGYFG-----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 1966 WGLNTGLGCTPCNCGIASESTQCDDD---NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+G + C PC C S+ QCDD +GQC C G TG CD A T
Sbjct: 2005 FGPD----CLPCGC---SDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSA 2057
Query: 2023 H--------CNCNTGY-SVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP---QEG--- 2067
H C CN Y G C C+ G K RC ++ + Q+G
Sbjct: 2058 HATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCA-KVARCSQKGTKVSCSCQKGYKG 2116
Query: 2068 ----CLECDSCTDAL 2078
C E D C D L
Sbjct: 2117 DGHSCTEIDPCADGL 2131
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/321 (26%), Positives = 115/321 (35%), Gaps = 55/321 (17%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDE-LDVCQPCQCDPHFSTGNCEEESGRCE 380
GG+C C C T P RW + V Q C + F E R
Sbjct: 1887 GGRCDTFTTFDASGECGSCVNT---PSCPRWSKPKGVKQKCLYNLPFKRNL---EGCRER 1940
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCT------CNLNGTEGEHCTPTDGLCPCKYNYAGK 434
C Q P C GYF +C+ C CN G + + T G C C + G
Sbjct: 1941 CSLVIQIPRCCK---GYFGR-DCQACPGGPDAPCNNRGVCLDQYSAT-GECKCNTGFNGT 1995
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLT--GDCTCKSKYSGRTCNQ-------CQ 485
+CE+C G + P+C C C+ G D +T G C C++ ++G +C+ C
Sbjct: 1996 ACEMCWPGRFGPDCLPCGCSDHGQCD---DGITGSGQCLCETGWTGPSCDTQAVLPAVCT 2052
Query: 486 AGYYNYPTCK-----PCNCDTSG-----TEPSICDDVSGQC--ICKAGFGGPRCD-QCLS 532
+ TCK CN D G T C +G C + + G + C
Sbjct: 2053 PPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQK 2112
Query: 533 GYYMQVLGRERQCVPCNCDP-TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
GY G C DP + C C +T G +C +C Y D L
Sbjct: 2113 GY----KGDGHSCT--EIDPCADGLNGGCHEHATCK-MTGPGKHKC-ECKSHY--VGDGL 2162
Query: 592 SCNCDVSGSIGSTCDDNGLCH 612
+C + I DNG CH
Sbjct: 2163 NCEPE-QLPIDRCLQDNGQCH 2182
Score = 60.9 bits (141), Expect = 8e-08
Identities = 61/235 (25%), Positives = 90/235 (38%), Gaps = 41/235 (17%)
Query: 439 CEDGYYSPECKNCECNT--VGSVSYVC-DKL--TGDCTCKSKYSGRTCNQCQAGYYNYPT 493
C G++ P+C+ C N V + +C D + TG C C +SG C C G Y
Sbjct: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395
Query: 494 CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
+ C+C D G C C G+ G CD + NC+ T
Sbjct: 1396 DQACSCVHGRCNQGPLGD--GSCDCDVGWRGVHCDNATT--------------EDNCNGT 1439
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN-CDVS-GSIGSTCD---- 606
TS NCLTN G +C+ G+ C + N C++S G + D
Sbjct: 1440 CHTS--------ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT 1491
Query: 607 --DNGLCHCKSNF--DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPA 657
+C CK+ + DG C N+ C++ N + + A C +PA
Sbjct: 1492 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDK-NAECTQTGPNQAACNCLPA 1545
Score = 59.3 bits (137), Expect = 3e-07
Identities = 64/259 (24%), Positives = 89/259 (34%), Gaps = 35/259 (13%)
Query: 381 CRPEFQPPDCSSCAYG--YFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI 438
CR ++ P C +G + P CN G+ E +G C C+ + G +CE
Sbjct: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEG-NGTCSCQEGFGGTACET 149
Query: 439 C-EDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC 497
C +D + P C + CN V V G C C S Y+G C++ P C
Sbjct: 150 CADDNLFGPSCSSV-CNCVHGVCNSGLDGDGTCECYSAYTGPKCDK------PIPECAAL 202
Query: 498 NC-DTSGTEPSICDDVSGQCICKAGF--GGPRCDQ--------CLSGYYMQVLGRERQCV 546
C + S PS D+ +C C + G CD C + LG R
Sbjct: 203 LCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSC 262
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC---------DV 597
C G D C NFG + + Y P C C V
Sbjct: 263 TCQEGYRGDGQVCLPVD---PCQINFGNCP-TKSTVCKYDGPGQSHCECKEHYQNFVPGV 318
Query: 598 SGSIGSTCDDNGLCHCKSN 616
S+ C + CH +N
Sbjct: 319 GCSMTDICKSDNPCHRNAN 337
Score = 56.0 bits (129), Expect = 2e-06
Identities = 56/214 (26%), Positives = 80/214 (37%), Gaps = 24/214 (11%)
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACI 1931
++C P +G D S +I +C C N G C ++ ++C
Sbjct: 17 NFCSPAETTGQARRCDRKSLLTIRTECRSCALNL-GVKCPDGYTMITSGSVGVRDCRYT- 74
Query: 1932 CDEFGMADCDSTTGTC--VCRPGVIGEKCDRCAPDHWGLNT----GLGCTPCNC-GIASE 1984
F + + C +CR + RC P WG + G +PCN G +E
Sbjct: 75 ---FEVRTYSLSLPGCRHICRKDYLQP---RCCPGRWGPDCIECPGGAGSPCNGRGSCAE 128
Query: 1985 STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATGQCE 2043
+ NG C C +G G C+ CA N C CNC G + + G CE
Sbjct: 129 GME---GNGTCSCQEGFGGTACETCADD--NLFGPSCSSVCNCVHGVCNSGL-DGDGTCE 182
Query: 2044 CLPGVIGEKCDR-CPERWVLIPQEGCLECDSCTD 2076
C G KCD+ PE L+ E C T+
Sbjct: 183 CYSAYTGPKCDKPIPECAALLCPENS-RCSPSTE 215
Score = 55.2 bits (127), Expect = 4e-06
Identities = 72/281 (25%), Positives = 100/281 (35%), Gaps = 35/281 (12%)
Query: 393 CAYGYFDYPNCKPC------TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
C G+F P C+PC C NG + T G+C C ++G +CE C +G Y
Sbjct: 1336 CCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGT-GVCECGEGFSGTACETCTEGKYGI 1393
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC-KPCNCDTSGTE 505
C C+ V G C C + G C+ TC NC T+
Sbjct: 1394 HCDQA-CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN--- 1449
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL-GRERQCVPCNCDPTGSTSTSCSA-- 562
D + C C AGF G C + ++ G C G +C A
Sbjct: 1450 ----SDGTASCKCAAGFQG-NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY 1504
Query: 563 --DG----KCN-CLTNFGGAQCDQCSPGYYKYPDCLSCNC-DVSGSIGSTCDDNGLCHCK 614
DG + N CL N GG CD+ + P+ +CNC G C +C K
Sbjct: 1505 TGDGIVCLEINPCLENHGG--CDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK 1562
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSV 655
N ++ C + C C P + F GS+
Sbjct: 1563 -NGGCSEFAICN---HTGQVERTCTCKPNYIGDGFTCRGSI 1599
Score = 55.2 bits (127), Expect = 4e-06
Identities = 67/246 (27%), Positives = 91/246 (36%), Gaps = 49/246 (19%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C GY G RDC C P NN + D + + C C G+ G CE C
Sbjct: 1950 CCKGYFG-------RDCQACPGGPDAPCNNRGVCLD--QYSATGECKCNTGFNGTACEMC 2000
Query: 1856 AAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD---SINGDCLKCVNNTAGAACN- 1911
G +G P+ C PC CS D G CD + +G CL C G +C+
Sbjct: 2001 WPGRFG-PD---------CLPCGCS------DHGQCDDGITGSGQCL-CETGWTGPSCDT 2043
Query: 1912 ------LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG-EKCDRCAPD 1964
+C P A +N T C C+ D + T C+ G K RC+
Sbjct: 2044 QAVLPAVCTPPCSAHATCKENNT-CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
T + C+ C G + C + + CA G+ G C + A T G C
Sbjct: 2103 ----GTKVSCS-CQKGYKGDGHSCTEID---PCADGLNG-GCHEHAT--CKMTGPGKHKC 2151
Query: 2025 NCNTGY 2030
C + Y
Sbjct: 2152 ECKSHY 2157
Score = 55.2 bits (127), Expect = 4e-06
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 38/190 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD----NGMCICPKNVEGENCD 1412
G+C C G C C G +G P+C PC C CDD +G C+C G +CD
Sbjct: 1984 GECKCNTGFNGTACEMCWPGRFG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD 2042
Query: 1413 R-------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ------CEADSGKCA--CRENV 1457
C P + + C CN L G+ + C+ D+G CA R +
Sbjct: 2043 TQAVLPAVCTPPCSAHATCKENNTCECN-LDYEGDGITCTVVDFCKQDNGGCAKVARCSQ 2101
Query: 1458 RG-RVCDHCVPGHYAFPDCYQCT------------CNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G +V C G+ D + CT C+ H T + +C CK++
Sbjct: 2102 KGTKVSCSCQKGYKG--DGHSCTEIDPCADGLNGGCHEHATC-KMTGPGKHKCECKSHYV 2158
Query: 1505 GQACDTCKEE 1514
G + C+ E
Sbjct: 2159 GDGLN-CEPE 2167
Score = 53.6 bits (123), Expect = 1e-05
Identities = 68/263 (25%), Positives = 97/263 (36%), Gaps = 39/263 (14%)
Query: 518 CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
C GF GP C+QC G+ C G + S +G C C F G+QC
Sbjct: 728 CCKGFYGPDCNQCPGGFSNP------------CSGNGQCADSLGGNGTCICEEGFQGSQC 775
Query: 578 DQCSPGYYKYPDC-LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNY-PAC 635
CS P C C C V G+ + D +G C + DG+ C +Q P
Sbjct: 776 QFCSDPNKYGPRCNKKCLC-VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV 834
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ-CN 694
+ C+ T ++ G+ A +C+ G +C++ P P GC +
Sbjct: 835 QFCHIH---ATCEYSN-GT--ASCICKAGYEGDGTLCSEMDP----CTGLTPGGCSRNAE 884
Query: 695 CNLAGTLNSLGACN---TKSGQ-CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD- 749
C GT C T +G+ C + C D L G EC+C
Sbjct: 885 CIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP--GQNECECKK 942
Query: 750 --IGGSID----NNCDKTTGQCH 766
G ID +C + TG+CH
Sbjct: 943 GFRGNGIDCEPITSCLEQTGKCH 965
Score = 52.0 bits (119), Expect = 4e-05
Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 17/140 (12%)
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD------QCSPGYYKYPDCLSCN------ 594
P N +PT + C G+ L + C+ +C G+Y PDC C
Sbjct: 689 PANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYG-PDCNQCPGGFSNP 747
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EECNCDPRGVTASFAGCG 653
C +G + NG C C+ F G++C C + P C ++C C G
Sbjct: 748 CSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDG 807
Query: 654 SVPAGELCQCKDRVQGRICN 673
+ G C+D GR+C+
Sbjct: 808 ACLTG---TCRDGSAGRLCD 824
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/203 (24%), Positives = 65/203 (32%), Gaps = 21/203 (10%)
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--KCVNNTAGAA 1909
C C+ Y+ T + C SG G N KC G
Sbjct: 677 CVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPD 736
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCA-PDHWGL 1968
CN C GF + C AD GTC+C G G +C C+ P+ +G
Sbjct: 737 CNQCPGGFSNPCSGNGQC----------ADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP 786
Query: 1969 NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
C C G + D C G G+ CD+ + Y + H C
Sbjct: 787 RCNKKCL-CVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCE- 844
Query: 2029 GYSVGFMCNATGQCECLPGVIGE 2051
YS N T C C G G+
Sbjct: 845 -YS-----NGTASCICKAGYEGD 861
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 31/180 (17%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
C GY+G +C+ C A C++ G+C+ C G C+ C P F D
Sbjct: 1950 CCKGYFG-RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNR 1482
C C C+ G + + SG+C C G CD P C+
Sbjct: 2009 ----CLPCGCSDHGQCDDGI---TGSGQCLCETGWTGPSCD----TQAVLPAVCTPPCSA 2057
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK-CFCFGKTTRCSSS 1541
H T C +N C C + G TC F QD+ GC K C K T+ S S
Sbjct: 2058 HAT----CKENNT-CECNLDYEGDGI-TCTVVDFCKQDNG--GCAKVARCSQKGTKVSCS 2109
Score = 50.8 bits (116), Expect = 9e-05
Identities = 72/285 (25%), Positives = 99/285 (34%), Gaps = 41/285 (14%)
Query: 358 CQPCQCDPH---FSTGNCEEE---SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLN 411
CQPC + F G C + +G CEC F C +C G + + C+C ++
Sbjct: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 1403
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + DG C C + G C D + + N C+T + D T C
Sbjct: 1404 GRCNQG-PLGDGSCDCDVGWRGVHC----DNATTEDNCNGTCHTSANCLTNSDG-TASCK 1457
Query: 472 CKSKY--SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ 529
C + + +G C A + C D T P C CKAG+ G
Sbjct: 1458 CAAGFQGNGTICTAINACEISNGGCS-AKADCKRTTPG-----RRVCTCKAGYTGDGI-V 1510
Query: 530 CLSGYYMQVLGRERQC-VPCNCDPTGSTSTSCSADGKCNCLTNF--GGAQCDQCSPGYYK 586
CL L C C TG + CNCL + G C + K
Sbjct: 1511 CLE--INPCLENHGGCDKNAECTQTGPNQAA------CNCLPAYTGDGKVCTLINVCLTK 1562
Query: 587 YPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY 630
C C+ +G + TC CK N+ G TCR Y
Sbjct: 1563 NGGCSEFAICNHTGQVERTCT------CKPNYIGDGF-TCRGSIY 1600
Score = 50.4 bits (115), Expect = 1e-04
Identities = 69/314 (21%), Positives = 102/314 (32%), Gaps = 47/314 (14%)
Query: 1737 QCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
+C + + G C QC P GF PC NG G C+ C + G C+FC
Sbjct: 727 KCCKGFYGPDCNQC-------PGGFSNPCSGNGQCADSLGGNGTCI-CEEGFQGSQCQFC 778
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC- 1855
C+ C S+ L+ + + C+ Q G ++C
Sbjct: 779 SDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCH 838
Query: 1856 --AAGYYGIPEDTDLHTGDYCKPCNCSGNINP---QDPGSCDSINGDCLKCVNNTAGAAC 1910
A Y + + Y ++P PG C S N +C+K T C
Sbjct: 839 IHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC-SRNAECIK--TGTGTHTC 895
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
+C G+ G+ C+ G C PG +C+ C G
Sbjct: 896 -VCQQGWTGNGRDCSEINNCLLPSAG--GCHDNASCLYVGPG--QNECE-CKKGFRG--N 947
Query: 1971 GLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGY 2030
G+ C P T C + G+C C ++G W+ C C GY
Sbjct: 948 GIDCEPI--------TSCLEQTGKCHPL-----ASCQSTSSGVWS--------CVCQEGY 986
Query: 2031 -SVGFMCNATGQCE 2043
GF+C E
Sbjct: 987 EGDGFLCYGNAAVE 1000
Score = 48.4 bits (110), Expect = 5e-04
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 36/192 (18%)
Query: 1320 GLCREAMFSITSEYNSGA-----RPCLCD--FMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
G CR +T + + + R C+ FMG L G Q C VI R C A
Sbjct: 1282 GRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTL---FIGCQPKCVRTVITRECCA 1338
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
G++G P C+PC + +C NG+C+ C + G C+ C +
Sbjct: 1339 ---GFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
Query: 1423 VQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY---QC 1478
CD C+C V G Q G C C RG CD+ C+ C
Sbjct: 1395 ----CDQACSC----VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC 1446
Query: 1479 TCNRHGTTYDVC 1490
N GT C
Sbjct: 1447 LTNSDGTASCKC 1458
Score = 48.0 bits (109), Expect = 6e-04
Identities = 46/167 (27%), Positives = 59/167 (35%), Gaps = 24/167 (14%)
Query: 1373 CRTGYYGFPNCRPCH------CPSTAICDD----NGMCICPKNVEGENCDRCK-PYTFNF 1421
C G+YG P+C C C C D NG CIC + +G C C P +
Sbjct: 728 CCKGFYG-PDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG- 785
Query: 1422 DVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCN 1481
R C C G N++ + CR+ GR+CD P Y C+
Sbjct: 786 --PRCNKKCLC-VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--CGP--YVQFCH 838
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK 1528
H T TA C CK G T E P GC++
Sbjct: 839 IHATC--EYSNGTASCICKAGYEGDG--TLCSEMDPCTGLTPGGCSR 881
Score = 47.2 bits (107), Expect = 0.001
Identities = 58/219 (26%), Positives = 77/219 (35%), Gaps = 31/219 (14%)
Query: 568 CLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCRE 627
C F G QC C PG + C + G G+ G+C C F G C+TC E
Sbjct: 1336 CCAGFFGPQCQPC-PGNAQNV-CFGNGICLDGVNGT-----GVCECGEGFSGTACETCTE 1388
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAG---ELCQCKDRVQGRICNDCKPLYWNLQE 684
Y + C+C G GS C + CN N
Sbjct: 1389 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLT 1448
Query: 685 YNPFGCEQCNCNLA----GTL-NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRL 735
N G C C GT+ ++ AC +G C CK+ R+ C G+
Sbjct: 1449 -NSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--- 1504
Query: 736 QTNDVFGCTECD-C-DIGGSIDNNCDKT-TG----QCHC 767
T D C E + C + G D N + T TG C+C
Sbjct: 1505 -TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC 1542
Score = 46.8 bits (106), Expect = 0.001
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 33/140 (23%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD---VNTGICLNCADNTIGD 1791
EC+C + G +CE C G + P C+PC C+ H QCD +G CL C G
Sbjct: 1985 ECKCNTGFNGTACEMCWPGRFG-PD--CLPCGCSDHG-QCDDGITGSGQCL-CETGWTGP 2039
Query: 1792 HCE-------FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS----CD--------- 1831
C+ C AT ++ C C + Y + + C
Sbjct: 2040 SCDTQAVLPAVCTPPCSAHATC---KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKV 2096
Query: 1832 --LSENGSLISCNCQPGYGG 1849
S+ G+ +SC+CQ GY G
Sbjct: 2097 ARCSQKGTKVSCSCQKGYKG 2116
Score = 46.4 bits (105), Expect = 0.002
Identities = 78/303 (25%), Positives = 108/303 (35%), Gaps = 47/303 (15%)
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C + P C YG P+C C G P G C + G ICE
Sbjct: 719 CNATVKIPKCCKGFYG----PDCNQCP-------GGFSNPCSGNGQCADSLGGNGTCICE 767
Query: 441 DGYYSPECKNC-ECNTVG-SVSYVCDKLTGDCTCKSKYSGR----TCNQCQAGYYNYPTC 494
+G+ +C+ C + N G + C + G C + G TC AG
Sbjct: 768 EGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQT 827
Query: 495 KPCNCDTSGTE-PSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
C + C+ +G CICKAG+ G D L + PC
Sbjct: 828 SACGPYVQFCHIHATCEYSNGTASCICKAGYEG---DGTLCS----------EMDPC--- 871
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCNCDVSGSIGSTCDDNGL 610
TG T CS + +C T G C C G+ DC N + S G C DN
Sbjct: 872 -TGLTPGGCSRNAEC-IKTGTGTHTC-VCQQGWTGNGRDCSEINNCLLPSAGG-CHDNAS 927
Query: 611 CHCKSNFDGAKCDTCREQFY-NYPACEE-CNC-DPRGVTASFAGCGSVPAGE-LCQCKDR 666
C +C+ C++ F N CE +C + G A C S +G C C++
Sbjct: 928 CLYVGPGQN-ECE-CKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEG 985
Query: 667 VQG 669
+G
Sbjct: 986 YEG 988
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/184 (25%), Positives = 64/184 (34%), Gaps = 27/184 (14%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRP-CHCPSTAIC----DDNGMCICPKNVEGENC 1411
G C C+ G C C P+C C+C +C D +G C C G C
Sbjct: 134 GTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH-GVCNSGLDGDGTCECYSAYTGPKC 192
Query: 1412 DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE------ADSGKCACRENVRGRVCDHC 1465
D+ P ++ C+P N+L+C+ D C ++C
Sbjct: 193 DKPIPECAALLCP---ENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPH 249
Query: 1466 VPGHYAFPDCYQCTCNR--HG-----TTYDVCDQNTAQC-----YCKTNVRGQACDTCKE 1513
Y P+ + CTC G D C N C CK + GQ+ CKE
Sbjct: 250 AHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKE 309
Query: 1514 EYFN 1517
Y N
Sbjct: 310 HYQN 313
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 15/97 (15%)
Query: 690 CEQCNCNLAGTLNSLGACNTK---SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFG--CT 744
C +C N G+C +G C C++ G C+ C D +++FG C+
Sbjct: 109 CIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCAD-------DNLFGPSCS 161
Query: 745 E-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
C+C + G ++ D G C C+S G +CD+PI
Sbjct: 162 SVCNC-VHGVCNSGLDGD-GTCECYSAYTGPKCDKPI 196
Score = 43.6 bits (98), Expect = 0.014
Identities = 66/257 (25%), Positives = 86/257 (33%), Gaps = 61/257 (23%)
Query: 1811 DCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
DC+ C P N SC G+ +C+CQ G+GG CE CA D +L
Sbjct: 108 DCIECPGGAGSPCNGRG-SCAEGMEGNG-TCSCQEGFGGTACETCA--------DDNLFG 157
Query: 1871 GDYCKPCNCSGNINPQDPGSCDS-INGD-CLKCVNNTAGAACNLCAPGFYGDAIFSKNCT 1928
CNC G C+S ++GD +C + G C+ P C
Sbjct: 158 PSCSSVCNCV-------HGVCNSGLDGDGTCECYSAYTGPKCDKPIP----------ECA 200
Query: 1929 ACICDEFGMADC---DSTTGTCVCRPGVIGE--KCDRCAPDHWGLNTGLGCTPCNCGIAS 1983
A +C E D C C P G+ CD P C C +
Sbjct: 201 ALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP----------CLRKICHPHA 250
Query: 1984 ESTQCDDDNGQCRCAKGV--TGKQC---DQCAAGFWN---------YTKDGCDHCNCNTG 2029
T + C C +G G+ C D C F N Y G HC C
Sbjct: 251 HCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH 310
Query: 2030 YS---VGFMCNATGQCE 2043
Y G C+ T C+
Sbjct: 311 YQNFVPGVGCSMTDICK 327
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/225 (26%), Positives = 81/225 (36%), Gaps = 38/225 (16%)
Query: 576 QCDQCSPGYYKYPDCLSCN------CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
Q +C GY+ DC +C C+ G G C C + F+G C+ C
Sbjct: 1946 QIPRCCKGYFGR-DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 630 YNYPACEECNCDPR-----GVTAS-FAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ P C C C G+T S C + G C + V +C + +
Sbjct: 2005 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQ-AVLPAVCTPPCSAHATCK 2062
Query: 684 EYNPFGCEQCNCNLAG---TLNSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ 736
E N CE CN + G T + C +G C C Q + C C G+
Sbjct: 2063 ENNT--CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC-SCQKGY---- 2114
Query: 737 TNDVFGCTECD-CD---IGGSIDNNCDKTTG----QCHCHSRVEG 773
D CTE D C GG ++ K TG +C C S G
Sbjct: 2115 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 2159
Score = 41.5 bits (93), Expect = 0.056
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
CD F D G+CV P C R + L P + +C
Sbjct: 1890 CDTFTTFDASGECGSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLV 1944
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGE 2051
RC KG G+ C C G D CN N G + +ATG+C+C G G
Sbjct: 1945 IQIPRCCKGYFGRDCQACPGG-----PDA--PCN-NRGVCLD-QYSATGECKCNTGFNGT 1995
Query: 2052 KCDRCPERWVLIPQEGCLECDSCTD 2076
C+ C W CL C C+D
Sbjct: 1996 ACEMC---WPGRFGPDCLPC-GCSD 2016
Score = 39.5 bits (88), Expect = 0.22
Identities = 38/146 (26%), Positives = 49/146 (33%), Gaps = 13/146 (8%)
Query: 340 CRPTYYRPY---GKRWDELDVCQPCQCDPHFSTGNCEEE---SGRCECRPEFQPPDCSSC 393
CR Y +P G+ + C P G+C E +G C C+ F C +C
Sbjct: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
Query: 394 AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCEC 453
A P+C CN DG C C Y G C+ PEC C
Sbjct: 151 ADDNLFGPSCS-SVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD-----KPIPECAALLC 204
Query: 454 NTVGSVS-YVCDKLTGDCTCKSKYSG 478
S D+ +C C Y G
Sbjct: 205 PENSRCSPSTEDENKLECKCLPNYRG 230
Score = 39.5 bits (88), Expect = 0.22
Identities = 62/247 (25%), Positives = 88/247 (35%), Gaps = 47/247 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP----SGFCVPCQCNGHSDQCDVNTGICL--NCADNTI 1789
C C ++G C+ C++ + P CV CN D + G CL C D +
Sbjct: 764 CICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRID----SDGACLTGTCRDGSA 819
Query: 1790 GDHCEFCMSG-------YHGDATVGTPRDCLICACPMPYPSNNFALS----C-DLSENGS 1837
G C+ S H AT C C Y + S C L+ G
Sbjct: 820 GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC 879
Query: 1838 LISCNC-QPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
+ C + G G C C G+ G D C+ N G C N
Sbjct: 880 SRNAECIKTGTGTHTC-VCQQGWTGNGRD-----------CSEINNCLLPSAGGCHD-NA 926
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG----MADCDSTTG---TCVC 1949
CL C C GF G+ I + T+C+ ++ G +A C ST+ +CVC
Sbjct: 927 SCLYV--GPGQNECE-CKKGFRGNGIDCEPITSCL-EQTGKCHPLASCQSTSSGVWSCVC 982
Query: 1950 RPGVIGE 1956
+ G G+
Sbjct: 983 QEGYEGD 989
Score = 38.7 bits (86), Expect = 0.39
Identities = 41/152 (26%), Positives = 51/152 (33%), Gaps = 18/152 (11%)
Query: 1361 CKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFN 1420
C P G C C G G P C + NG C C + G C+ C N
Sbjct: 100 CCPGRWGPDCIECPGGA-GSPCNGRGSCAEGM--EGNGTCSCQEGFGGTACETCA--DDN 154
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTC 1480
CNC GV + L G C C G CD + P+C C
Sbjct: 155 LFGPSCSSVCNC-VHGVCNSGLD---GDGTCECYSAYTGPKCDKPI------PECAALLC 204
Query: 1481 NRHG-TTYDVCDQNTAQCYCKTNVRGQA--CD 1509
+ + D+N +C C N RG CD
Sbjct: 205 PENSRCSPSTEDENKLECKCLPNYRGDGKYCD 236
Score = 38.7 bits (86), Expect = 0.39
Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 11/94 (11%)
Query: 1427 CDDCNCNPLGVV-GNQLQCEA--DSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRH 1483
C C N V GN + + +G C C E G C+ C G Y C+C H
Sbjct: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 1403
Query: 1484 GTTYDVCDQ---NTAQCYCKTNVRGQACDTCKEE 1514
G C+Q C C RG CD E
Sbjct: 1404 GR----CNQGPLGDGSCDCDVGWRGVHCDNATTE 1433
Score = 37.9 bits (84), Expect = 0.68
Identities = 34/120 (28%), Positives = 47/120 (39%), Gaps = 20/120 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C + G +CE CA+ + PS C S C+ G+C + D GD
Sbjct: 136 CSCQEGFGGTACETCADDNLFGPS--C--------SSVCNCVHGVCNSGLD---GDGTCE 182
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C S Y G +C CP N S +E+ + + C C P Y G +YC
Sbjct: 183 CYSAYTGPKCDKPIPECAALLCP-----ENSRCS-PSTEDENKLECKCLPNYRGDG-KYC 235
Score = 36.7 bits (81), Expect = 1.6
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 8/56 (14%)
Query: 1465 CVPGHYAFPDCYQCT------CNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
C PG + PDC +C CN G+ + + N C C+ G AC+TC ++
Sbjct: 100 CCPGRWG-PDCIECPGGAGSPCNGRGSCAEGMEGN-GTCSCQEGFGGTACETCADD 153
Score = 35.9 bits (79), Expect = 2.8
Identities = 65/274 (23%), Positives = 90/274 (32%), Gaps = 40/274 (14%)
Query: 248 NLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE-PCNCHN--HTTEC---- 300
N + + +C GP CN+C GF Q D C C ++C
Sbjct: 720 NATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCS 779
Query: 301 ---TYDPEIDEKRLSL--DINGRYEGGGKCL--NCQHNTEGINCNKCRPTYYRPYGKRWD 353
Y P ++K L + N R + G CL C+ + G C+K + + PY +
Sbjct: 780 DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDK-QTSACGPYVQFCH 838
Query: 354 ELDVCQ------PCQCDPHF-STGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPC 406
C+ C C + G E C P CS A C
Sbjct: 839 IHATCEYSNGTASCICKAGYEGDGTLCSEMDPC---TGLTPGGCSRNAECIKTGTGTHTC 895
Query: 407 TCNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCEC------NTVGSV 459
C T G C+ + C AG + Y P CEC N +
Sbjct: 896 VCQQGWTGNGRDCSEINN---CLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCE 952
Query: 460 SYV-CDKLTGDC----TCKSKYSGRTCNQCQAGY 488
C + TG C +C+S SG CQ GY
Sbjct: 953 PITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
Score = 35.1 bits (77), Expect = 4.8
Identities = 21/80 (26%), Positives = 28/80 (35%), Gaps = 6/80 (7%)
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD--VC---DQNTAQCYCKTNVRGQACDTC 1511
VR + C G + P C C N + +C T C C G AC+TC
Sbjct: 1328 VRTVITRECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETC 1386
Query: 1512 KEEYFNLQDDNPDGCTKCFC 1531
E + + D C C
Sbjct: 1387 TEGKYGIHCDQACSCVHGRC 1406
Score = 34.3 bits (75), Expect = 8.4
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 9/63 (14%)
Query: 1996 RCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
+C KG G C+QC GF N G C + G G C C G G +C
Sbjct: 727 KCCKGFYGPDCNQCPGGFSN-PCSGNGQCADSLG--------GNGTCICEEGFQGSQCQF 777
Query: 2056 CPE 2058
C +
Sbjct: 778 CSD 780
>AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.
Length = 1736
Score = 75.4 bits (177), Expect = 4e-12
Identities = 65/240 (27%), Positives = 94/240 (39%), Gaps = 39/240 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + G +CE C EG Y + C +G +Q + G C +C G HC+
Sbjct: 557 CECGEGFSGTACETCTEGKYGIHCDQACSC-VHGRCNQGPLGDGSC-DCDVGWRGVHCDN 614
Query: 1796 CMSGYHGDATVGTPRDCLI-------CACPMPYPSNNFAL----SCDLSENGSLISCNCQ 1844
+ + + T T +CL C C + N +C++S G +C+
Sbjct: 615 ATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 674
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP--QDPGSCDSINGDCLKCV 1902
G R C AGY G G C INP ++ G CD N +C +
Sbjct: 675 RTTPGRRVCTCKAGYTG--------DGIVCL------EINPCLENHGGCDK-NAECTQTG 719
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACI-----CDEFGMAD-CDSTTGTCVCRPGVIGE 1956
N AACN C P + GD C+ C EF + + TC C+P IG+
Sbjct: 720 PNQ--AACN-CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGD 776
Score = 70.1 bits (164), Expect = 1e-10
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 529 QCLSGYYMQVLGRERQCVP----CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
+C GY+ GR+ Q P C+ G SA G+C C T F G C+ C PG
Sbjct: 1134 RCCKGYF----GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 1189
Query: 585 YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT 624
+ PDCL C C G +G C C++ + G CDT
Sbjct: 1190 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGTSCDT 1228
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/99 (37%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 1414 CKPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYA 1471
CK Y F D Q G D CN GV +Q +G+C C G C+ C PG +
Sbjct: 1136 CKGY-FGRDCQACPGGPDAPCNNRGVCLDQYSA---TGECKCNTGFNGTACEMCWPGRFG 1191
Query: 1472 FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
PDC C C+ HG D + QC C+T G +CDT
Sbjct: 1192 -PDCLPCGCSDHGQCDDGI-TGSGQCLCETGWTGTSCDT 1228
Score = 64.9 bits (151), Expect = 5e-09
Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 50/246 (20%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPED---TDLHTGDYCKP-----CNCS---GNI 1883
NG+ + C C G+ G CE C G YGI D + +H P C+C +
Sbjct: 552 NGTGV-CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGV 610
Query: 1884 NPQDPGSCDSINGDC---LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG---M 1937
+ + + D+ NG C C+ N+ G A CA GF G+ AC G
Sbjct: 611 HCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAK 670
Query: 1938 ADCDSTT---GTCVCRPGVIGE-----KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
ADC TT C C+ G G+ + + C +H G C +E TQ
Sbjct: 671 ADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGG-----------CDKNAECTQTG 719
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ----CECL 2045
+ C C TG C TK+G G S +CN TGQ C C
Sbjct: 720 PNQAACNCLPAYTG-DGKVCTLINVCLTKNG--------GCSEFAICNHTGQVERTCTCK 770
Query: 2046 PGVIGE 2051
P IG+
Sbjct: 771 PNYIGD 776
Score = 64.5 bits (150), Expect = 7e-09
Identities = 78/272 (28%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 483 QCQAGYYNYPTCKPC--NCDTSGTEPSIC-DDVSGQ--CICKAGFGGPRCDQCLSGYYMQ 537
+C AG++ P C+PC N IC D V+G C C GF G C+ C G Y
Sbjct: 520 ECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 578
Query: 538 VLGRERQCV--PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
+ CV CN P G DG C+C + G CD + D + C
Sbjct: 579 HCDQACSCVHGRCNQGPLG--------DGSCDCDVGWRGVHCDNATT-----EDNCNGTC 625
Query: 596 DVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC-GS 654
S + + D C C + F G C ACE N G ++ A C +
Sbjct: 626 HTSANCLTNSDGTASCKCAAGFQG-NGTICTA----INACEISN----GGCSAKADCKRT 676
Query: 655 VPAGELCQCKDRV--QGRICNDCKPLYWN------LQEYNPFGCEQ--CNCNLAGT---- 700
P +C CK G +C + P N E G Q CNC A T
Sbjct: 677 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGK 736
Query: 701 -LNSLGACNTKSGQC----VCKQHVG--ERQC 725
+ C TK+G C +C H G ER C
Sbjct: 737 VCTLINVCLTKNGGCSEFAIC-NHTGQVERTC 767
Score = 63.7 bits (148), Expect = 1e-08
Identities = 60/195 (30%), Positives = 76/195 (38%), Gaps = 42/195 (21%)
Query: 1913 CAPGFYGDAIFSKNCTACI------CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDH 1965
C G++G ++C AC C+ G+ D S TG C C G G C+ C P
Sbjct: 1135 CCKGYFG-----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 1189
Query: 1966 WGLNTGLGCTPCNCGIASESTQCDDD---NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+G + C PC C S+ QCDD +GQC C G TG CD A T
Sbjct: 1190 FGPD----CLPCGC---SDHGQCDDGITGSGQCLCETGWTGTSCDTQAVLPAVCTPPCSA 1242
Query: 2023 H--------CNCNTGY-SVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP---QEG--- 2067
H C CN Y G C C+ G K RC ++ + Q+G
Sbjct: 1243 HATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCA-KVARCSQKGTKVSCSCQKGYKG 1301
Query: 2068 ----CLECDSCTDAL 2078
C E D C D L
Sbjct: 1302 DGHSCTEIDPCADGL 1316
Score = 62.1 bits (144), Expect = 4e-08
Identities = 84/321 (26%), Positives = 115/321 (35%), Gaps = 55/321 (17%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDE-LDVCQPCQCDPHFSTGNCEEESGRCE 380
GG+C C C T P RW + V Q C + F E R
Sbjct: 1072 GGRCDTFTTFDASGECGSCVNT---PSCPRWSKPKGVKQKCLYNLPFKRNL---EGCRER 1125
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCT------CNLNGTEGEHCTPTDGLCPCKYNYAGK 434
C Q P C GYF +C+ C CN G + + T G C C + G
Sbjct: 1126 CSLVIQIPRCCK---GYFGR-DCQACPGGPDAPCNNRGVCLDQYSAT-GECKCNTGFNGT 1180
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLT--GDCTCKSKYSGRTCNQ-------CQ 485
+CE+C G + P+C C C+ G D +T G C C++ ++G +C+ C
Sbjct: 1181 ACEMCWPGRFGPDCLPCGCSDHGQCD---DGITGSGQCLCETGWTGTSCDTQAVLPAVCT 1237
Query: 486 AGYYNYPTCK-----PCNCDTSG-----TEPSICDDVSGQC--ICKAGFGGPRCD-QCLS 532
+ TCK CN D G T C +G C + + G + C
Sbjct: 1238 PPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQK 1297
Query: 533 GYYMQVLGRERQCVPCNCDP-TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
GY G C DP + C C +T G +C +C Y D L
Sbjct: 1298 GY----KGDGHSCT--EIDPCADGLNGGCHEHATCK-MTGPGKHKC-ECKSHY--VGDGL 1347
Query: 592 SCNCDVSGSIGSTCDDNGLCH 612
+C + I DNG CH
Sbjct: 1348 NCEPE-QLPIDRCLQDNGQCH 1367
Score = 60.9 bits (141), Expect = 8e-08
Identities = 61/235 (25%), Positives = 90/235 (38%), Gaps = 41/235 (17%)
Query: 439 CEDGYYSPECKNCECNT--VGSVSYVC-DKL--TGDCTCKSKYSGRTCNQCQAGYYNYPT 493
C G++ P+C+ C N V + +C D + TG C C +SG C C G Y
Sbjct: 521 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 580
Query: 494 CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
+ C+C D G C C G+ G CD + NC+ T
Sbjct: 581 DQACSCVHGRCNQGPLGD--GSCDCDVGWRGVHCDNATT--------------EDNCNGT 624
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN-CDVS-GSIGSTCD---- 606
TS NCLTN G +C+ G+ C + N C++S G + D
Sbjct: 625 CHTS--------ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT 676
Query: 607 --DNGLCHCKSNF--DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPA 657
+C CK+ + DG C N+ C++ N + + A C +PA
Sbjct: 677 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDK-NAECTQTGPNQAACNCLPA 730
Score = 55.6 bits (128), Expect = 3e-06
Identities = 67/246 (27%), Positives = 91/246 (36%), Gaps = 49/246 (19%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C GY G RDC C P NN + D + + C C G+ G CE C
Sbjct: 1135 CCKGYFG-------RDCQACPGGPDAPCNNRGVCLD--QYSATGECKCNTGFNGTACEMC 1185
Query: 1856 AAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD---SINGDCLKCVNNTAGAACN- 1911
G +G P+ C PC CS D G CD + +G CL C G +C+
Sbjct: 1186 WPGRFG-PD---------CLPCGCS------DHGQCDDGITGSGQCL-CETGWTGTSCDT 1228
Query: 1912 ------LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG-EKCDRCAPD 1964
+C P A +N T C C+ D + T C+ G K RC+
Sbjct: 1229 QAVLPAVCTPPCSAHATCKENNT-CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 1287
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
T + C+ C G + C + + CA G+ G C + A T G C
Sbjct: 1288 ----GTKVSCS-CQKGYKGDGHSCTEID---PCADGLNG-GCHEHAT--CKMTGPGKHKC 1336
Query: 2025 NCNTGY 2030
C + Y
Sbjct: 1337 ECKSHY 1342
Score = 55.2 bits (127), Expect = 4e-06
Identities = 72/281 (25%), Positives = 100/281 (35%), Gaps = 35/281 (12%)
Query: 393 CAYGYFDYPNCKPC------TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
C G+F P C+PC C NG + T G+C C ++G +CE C +G Y
Sbjct: 521 CCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGT-GVCECGEGFSGTACETCTEGKYGI 578
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC-KPCNCDTSGTE 505
C C+ V G C C + G C+ TC NC T+
Sbjct: 579 HCDQA-CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN--- 634
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL-GRERQCVPCNCDPTGSTSTSCSA-- 562
D + C C AGF G C + ++ G C G +C A
Sbjct: 635 ----SDGTASCKCAAGFQG-NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY 689
Query: 563 --DG----KCN-CLTNFGGAQCDQCSPGYYKYPDCLSCNC-DVSGSIGSTCDDNGLCHCK 614
DG + N CL N GG CD+ + P+ +CNC G C +C K
Sbjct: 690 TGDGIVCLEINPCLENHGG--CDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK 747
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSV 655
N ++ C + C C P + F GS+
Sbjct: 748 -NGGCSEFAICN---HTGQVERTCTCKPNYIGDGFTCRGSI 784
Score = 55.2 bits (127), Expect = 4e-06
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 38/190 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD----NGMCICPKNVEGENCD 1412
G+C C G C C G +G P+C PC C CDD +G C+C G +CD
Sbjct: 1169 GECKCNTGFNGTACEMCWPGRFG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGTSCD 1227
Query: 1413 R-------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ------CEADSGKCA--CRENV 1457
C P + + C CN L G+ + C+ D+G CA R +
Sbjct: 1228 TQAVLPAVCTPPCSAHATCKENNTCECN-LDYEGDGITCTVVDFCKQDNGGCAKVARCSQ 1286
Query: 1458 RG-RVCDHCVPGHYAFPDCYQCT------------CNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G +V C G+ D + CT C+ H T + +C CK++
Sbjct: 1287 KGTKVSCSCQKGYKG--DGHSCTEIDPCADGLNGGCHEHATC-KMTGPGKHKCECKSHYV 1343
Query: 1505 GQACDTCKEE 1514
G + C+ E
Sbjct: 1344 GDGLN-CEPE 1352
Score = 51.6 bits (118), Expect = 5e-05
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 31/180 (17%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
C GY+G +C+ C A C++ G+C+ C G C+ C P F D
Sbjct: 1135 CCKGYFG-RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 1193
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNR 1482
C C C+ G + + SG+C C G CD P C+
Sbjct: 1194 ----CLPCGCSDHGQCDDGI---TGSGQCLCETGWTGTSCD----TQAVLPAVCTPPCSA 1242
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK-CFCFGKTTRCSSS 1541
H T C +N C C + G TC F QD+ GC K C K T+ S S
Sbjct: 1243 HAT----CKENNT-CECNLDYEGDGI-TCTVVDFCKQDNG--GCAKVARCSQKGTKVSCS 1294
Score = 50.8 bits (116), Expect = 9e-05
Identities = 72/285 (25%), Positives = 99/285 (34%), Gaps = 41/285 (14%)
Query: 358 CQPCQCDPH---FSTGNCEEE---SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLN 411
CQPC + F G C + +G CEC F C +C G + + C+C ++
Sbjct: 530 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 588
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + DG C C + G C D + + N C+T + D T C
Sbjct: 589 GRCNQG-PLGDGSCDCDVGWRGVHC----DNATTEDNCNGTCHTSANCLTNSDG-TASCK 642
Query: 472 CKSKY--SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ 529
C + + +G C A + C D T P C CKAG+ G
Sbjct: 643 CAAGFQGNGTICTAINACEISNGGCS-AKADCKRTTPG-----RRVCTCKAGYTGDGI-V 695
Query: 530 CLSGYYMQVLGRERQC-VPCNCDPTGSTSTSCSADGKCNCLTNF--GGAQCDQCSPGYYK 586
CL L C C TG + CNCL + G C + K
Sbjct: 696 CLE--INPCLENHGGCDKNAECTQTGPNQAA------CNCLPAYTGDGKVCTLINVCLTK 747
Query: 587 YPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY 630
C C+ +G + TC CK N+ G TCR Y
Sbjct: 748 NGGCSEFAICNHTGQVERTCT------CKPNYIGDGF-TCRGSIY 785
Score = 48.4 bits (110), Expect = 5e-04
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 36/192 (18%)
Query: 1320 GLCREAMFSITSEYNSGA-----RPCLCD--FMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
G CR +T + + + R C+ FMG L G Q C VI R C A
Sbjct: 467 GRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTL---FIGCQPKCVRTVITRECCA 523
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
G++G P C+PC + +C NG+C+ C + G C+ C +
Sbjct: 524 ---GFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 579
Query: 1423 VQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY---QC 1478
CD C+C V G Q G C C RG CD+ C+ C
Sbjct: 580 ----CDQACSC----VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC 631
Query: 1479 TCNRHGTTYDVC 1490
N GT C
Sbjct: 632 LTNSDGTASCKC 643
Score = 47.2 bits (107), Expect = 0.001
Identities = 58/219 (26%), Positives = 77/219 (35%), Gaps = 31/219 (14%)
Query: 568 CLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCRE 627
C F G QC C PG + C + G G+ G+C C F G C+TC E
Sbjct: 521 CCAGFFGPQCQPC-PGNAQNV-CFGNGICLDGVNGT-----GVCECGEGFSGTACETCTE 573
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAG---ELCQCKDRVQGRICNDCKPLYWNLQE 684
Y + C+C G GS C + CN N
Sbjct: 574 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLT 633
Query: 685 YNPFGCEQCNCNLA----GTL-NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRL 735
N G C C GT+ ++ AC +G C CK+ R+ C G+
Sbjct: 634 -NSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--- 689
Query: 736 QTNDVFGCTECD-C-DIGGSIDNNCDKT-TG----QCHC 767
T D C E + C + G D N + T TG C+C
Sbjct: 690 -TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC 727
Score = 46.8 bits (106), Expect = 0.001
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 33/140 (23%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD---VNTGICLNCADNTIGD 1791
EC+C + G +CE C G + P C+PC C+ H QCD +G CL C G
Sbjct: 1170 ECKCNTGFNGTACEMCWPGRFG-PD--CLPCGCSDHG-QCDDGITGSGQCL-CETGWTGT 1224
Query: 1792 HCE-------FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS----CD--------- 1831
C+ C AT ++ C C + Y + + C
Sbjct: 1225 SCDTQAVLPAVCTPPCSAHATC---KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKV 1281
Query: 1832 --LSENGSLISCNCQPGYGG 1849
S+ G+ +SC+CQ GY G
Sbjct: 1282 ARCSQKGTKVSCSCQKGYKG 1301
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/225 (26%), Positives = 81/225 (36%), Gaps = 38/225 (16%)
Query: 576 QCDQCSPGYYKYPDCLSCN------CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
Q +C GY+ DC +C C+ G G C C + F+G C+ C
Sbjct: 1131 QIPRCCKGYFGR-DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 1189
Query: 630 YNYPACEECNCDPR-----GVTAS-FAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ P C C C G+T S C + G C + V +C + +
Sbjct: 1190 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGTSCDTQ-AVLPAVCTPPCSAHATCK 1247
Query: 684 EYNPFGCEQCNCNLAG---TLNSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ 736
E N CE CN + G T + C +G C C Q + C C G+
Sbjct: 1248 ENNT--CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC-SCQKGY---- 1299
Query: 737 TNDVFGCTECD-CD---IGGSIDNNCDKTTG----QCHCHSRVEG 773
D CTE D C GG ++ K TG +C C S G
Sbjct: 1300 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 1344
Score = 41.5 bits (93), Expect = 0.056
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
CD F D G+CV P C R + L P + +C
Sbjct: 1075 CDTFTTFDASGECGSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLV 1129
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGE 2051
RC KG G+ C C G D CN N G + +ATG+C+C G G
Sbjct: 1130 IQIPRCCKGYFGRDCQACPGG-----PDA--PCN-NRGVCLD-QYSATGECKCNTGFNGT 1180
Query: 2052 KCDRCPERWVLIPQEGCLECDSCTD 2076
C+ C W CL C C+D
Sbjct: 1181 ACEMC---WPGRFGPDCLPC-GCSD 1201
Score = 38.7 bits (86), Expect = 0.39
Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 11/94 (11%)
Query: 1427 CDDCNCNPLGVV-GNQLQCEA--DSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRH 1483
C C N V GN + + +G C C E G C+ C G Y C+C H
Sbjct: 530 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 588
Query: 1484 GTTYDVCDQ---NTAQCYCKTNVRGQACDTCKEE 1514
G C+Q C C RG CD E
Sbjct: 589 GR----CNQGPLGDGSCDCDVGWRGVHCDNATTE 618
Score = 36.7 bits (81), Expect = 1.6
Identities = 23/91 (25%), Positives = 33/91 (36%), Gaps = 10/91 (10%)
Query: 690 CEQCNCNLAGTLNSLGAC---NTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTEC 746
C+ C N+ G C + +G+C C C+ C G + C C
Sbjct: 1144 CQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD------CLPC 1197
Query: 747 DCDIGGSIDNNCDKTTGQCHCHSRVEGRRCD 777
C G D+ + GQC C + G CD
Sbjct: 1198 GCSDHGQCDDGITGS-GQCLCETGWTGTSCD 1227
Score = 35.1 bits (77), Expect = 4.8
Identities = 21/80 (26%), Positives = 28/80 (35%), Gaps = 6/80 (7%)
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD--VC---DQNTAQCYCKTNVRGQACDTC 1511
VR + C G + P C C N + +C T C C G AC+TC
Sbjct: 513 VRTVITRECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETC 571
Query: 1512 KEEYFNLQDDNPDGCTKCFC 1531
E + + D C C
Sbjct: 572 TEGKYGIHCDQACSCVHGRC 591
Score = 34.7 bits (76), Expect = 6.4
Identities = 37/140 (26%), Positives = 54/140 (38%), Gaps = 13/140 (9%)
Query: 1938 ADCDSTTGT--CVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC 1995
A C+ + GT C+C+ G G+ C+ ++ G TP C +E + C
Sbjct: 26 ATCEYSNGTASCICKAGYEGDGT-LCSE----MDPCTGLTPGGCSRNAECIKTGTGTHTC 80
Query: 1996 RCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
C +G TG D C+ N C+ N S ++ +CEC G G D
Sbjct: 81 VCQQGWTGNGRD-CSE-INNCLLPSAGGCHDNA--SCLYVGPGQNECECKKGFRGNGID- 135
Query: 2056 CPERWVLIPQEG-CLECDSC 2074
C + Q G C SC
Sbjct: 136 CEPITSCLEQTGKCHPLASC 155
>AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein.
Length = 1192
Score = 75.4 bits (177), Expect = 4e-12
Identities = 65/240 (27%), Positives = 94/240 (39%), Gaps = 39/240 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + G +CE C EG Y + C +G +Q + G C +C G HC+
Sbjct: 13 CECGEGFSGTACETCTEGKYGIHCDQACSC-VHGRCNQGPLGDGSC-DCDVGWRGVHCDN 70
Query: 1796 CMSGYHGDATVGTPRDCLI-------CACPMPYPSNNFAL----SCDLSENGSLISCNCQ 1844
+ + + T T +CL C C + N +C++S G +C+
Sbjct: 71 ATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 130
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP--QDPGSCDSINGDCLKCV 1902
G R C AGY G G C INP ++ G CD N +C +
Sbjct: 131 RTTPGRRVCTCKAGYTG--------DGIVCL------EINPCLENHGGCDK-NAECTQTG 175
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACI-----CDEFGMAD-CDSTTGTCVCRPGVIGE 1956
N AACN C P + GD C+ C EF + + TC C+P IG+
Sbjct: 176 PNQ--AACN-CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGD 232
Score = 69.7 bits (163), Expect = 2e-10
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 529 QCLSGYYMQVLGRERQCVP----CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
+C GY+ GR+ Q P C+ G SA G+C C T F G C+ C PG
Sbjct: 590 RCCKGYF----GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 645
Query: 585 YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT 624
+ PDCL C C G +G C C++ + G CDT
Sbjct: 646 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 684
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/99 (37%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 1414 CKPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYA 1471
CK Y F D Q G D CN GV +Q +G+C C G C+ C PG +
Sbjct: 592 CKGY-FGRDCQACPGGPDAPCNNRGVCLDQYSA---TGECKCNTGFNGTACEMCWPGRFG 647
Query: 1472 FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
PDC C C+ HG D + QC C+T G +CDT
Sbjct: 648 -PDCLPCGCSDHGQCDDGI-TGSGQCLCETGWTGPSCDT 684
Score = 64.5 bits (150), Expect = 7e-09
Identities = 68/240 (28%), Positives = 90/240 (37%), Gaps = 49/240 (20%)
Query: 1841 CNCQPGYGGARCEYCAAGYYGIPED---TDLHTGDYCKP-----CNCS---GNINPQDPG 1889
C C G+ G CE C G YGI D + +H P C+C ++ +
Sbjct: 13 CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 72
Query: 1890 SCDSINGDC---LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG---MADCDST 1943
+ D+ NG C C+ N+ G A CA GF G+ AC G ADC T
Sbjct: 73 TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT 132
Query: 1944 T---GTCVCRPGVIGE-----KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQC 1995
T C C+ G G+ + + C +H G C +E TQ + C
Sbjct: 133 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGG-----------CDKNAECTQTGPNQAAC 181
Query: 1996 RCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ----CECLPGVIGE 2051
C TG C TK+G G S +CN TGQ C C P IG+
Sbjct: 182 NCLPAYTG-DGKVCTLINVCLTKNG--------GCSEFAICNHTGQVERTCTCKPNYIGD 232
Score = 63.7 bits (148), Expect = 1e-08
Identities = 60/195 (30%), Positives = 76/195 (38%), Gaps = 42/195 (21%)
Query: 1913 CAPGFYGDAIFSKNCTACI------CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDH 1965
C G++G ++C AC C+ G+ D S TG C C G G C+ C P
Sbjct: 591 CCKGYFG-----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 645
Query: 1966 WGLNTGLGCTPCNCGIASESTQCDDD---NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+G + C PC C S+ QCDD +GQC C G TG CD A T
Sbjct: 646 FGPD----CLPCGC---SDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSA 698
Query: 2023 H--------CNCNTGY-SVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP---QEG--- 2067
H C CN Y G C C+ G K RC ++ + Q+G
Sbjct: 699 HATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCA-KVARCSQKGTKVSCSCQKGYKG 757
Query: 2068 ----CLECDSCTDAL 2078
C E D C D L
Sbjct: 758 DGHSCTEIDPCADGL 772
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/321 (26%), Positives = 115/321 (35%), Gaps = 55/321 (17%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDE-LDVCQPCQCDPHFSTGNCEEESGRCE 380
GG+C C C T P RW + V Q C + F E R
Sbjct: 528 GGRCDTFTTFDASGECGSCVNT---PSCPRWSKPKGVKQKCLYNLPFKRNL---EGCRER 581
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCT------CNLNGTEGEHCTPTDGLCPCKYNYAGK 434
C Q P C GYF +C+ C CN G + + T G C C + G
Sbjct: 582 CSLVIQIPRCCK---GYFGR-DCQACPGGPDAPCNNRGVCLDQYSAT-GECKCNTGFNGT 636
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLT--GDCTCKSKYSGRTCNQ-------CQ 485
+CE+C G + P+C C C+ G D +T G C C++ ++G +C+ C
Sbjct: 637 ACEMCWPGRFGPDCLPCGCSDHGQCD---DGITGSGQCLCETGWTGPSCDTQAVLPAVCT 693
Query: 486 AGYYNYPTCK-----PCNCDTSG-----TEPSICDDVSGQC--ICKAGFGGPRCD-QCLS 532
+ TCK CN D G T C +G C + + G + C
Sbjct: 694 PPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQK 753
Query: 533 GYYMQVLGRERQCVPCNCDP-TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
GY G C DP + C C +T G +C +C Y D L
Sbjct: 754 GY----KGDGHSCT--EIDPCADGLNGGCHEHATCK-MTGPGKHKC-ECKSHY--VGDGL 803
Query: 592 SCNCDVSGSIGSTCDDNGLCH 612
+C + I DNG CH
Sbjct: 804 NCEPE-QLPIDRCLQDNGQCH 823
Score = 55.2 bits (127), Expect = 4e-06
Identities = 67/239 (28%), Positives = 86/239 (35%), Gaps = 47/239 (19%)
Query: 511 DVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCV--PCNCDPTGSTSTSCSADGKCNC 568
D +G C C GF G C+ C G Y + CV CN P G DG C+C
Sbjct: 8 DGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLG--------DGSCDC 59
Query: 569 LTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQ 628
+ G CD + D + C S + + D C C + F G C
Sbjct: 60 DVGWRGVHCDNATT-----EDNCNGTCHTSANCLTNSDGTASCKCAAGFQG-NGTICTA- 112
Query: 629 FYNYPACEECNCDPRGVTASFAGC-GSVPAGELCQCKDRV--QGRICNDCKPLYWN---- 681
ACE N G ++ A C + P +C CK G +C + P N
Sbjct: 113 ---INACEISN----GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGC 165
Query: 682 --LQEYNPFGCEQ--CNCNLAGT-----LNSLGACNTKSGQC----VCKQHVG--ERQC 725
E G Q CNC A T + C TK+G C +C H G ER C
Sbjct: 166 DKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC-NHTGQVERTC 223
Score = 55.2 bits (127), Expect = 4e-06
Identities = 67/246 (27%), Positives = 91/246 (36%), Gaps = 49/246 (19%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C GY G RDC C P NN + D + + C C G+ G CE C
Sbjct: 591 CCKGYFG-------RDCQACPGGPDAPCNNRGVCLD--QYSATGECKCNTGFNGTACEMC 641
Query: 1856 AAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD---SINGDCLKCVNNTAGAACN- 1911
G +G P+ C PC CS D G CD + +G CL C G +C+
Sbjct: 642 WPGRFG-PD---------CLPCGCS------DHGQCDDGITGSGQCL-CETGWTGPSCDT 684
Query: 1912 ------LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG-EKCDRCAPD 1964
+C P A +N T C C+ D + T C+ G K RC+
Sbjct: 685 QAVLPAVCTPPCSAHATCKENNT-CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 743
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
T + C+ C G + C + + CA G+ G C + A T G C
Sbjct: 744 ----GTKVSCS-CQKGYKGDGHSCTEID---PCADGLNG-GCHEHAT--CKMTGPGKHKC 792
Query: 2025 NCNTGY 2030
C + Y
Sbjct: 793 ECKSHY 798
Score = 55.2 bits (127), Expect = 4e-06
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 38/190 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD----NGMCICPKNVEGENCD 1412
G+C C G C C G +G P+C PC C CDD +G C+C G +CD
Sbjct: 625 GECKCNTGFNGTACEMCWPGRFG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD 683
Query: 1413 R-------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ------CEADSGKCA--CRENV 1457
C P + + C CN L G+ + C+ D+G CA R +
Sbjct: 684 TQAVLPAVCTPPCSAHATCKENNTCECN-LDYEGDGITCTVVDFCKQDNGGCAKVARCSQ 742
Query: 1458 RG-RVCDHCVPGHYAFPDCYQCT------------CNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G +V C G+ D + CT C+ H T + +C CK++
Sbjct: 743 KGTKVSCSCQKGYKG--DGHSCTEIDPCADGLNGGCHEHATC-KMTGPGKHKCECKSHYV 799
Query: 1505 GQACDTCKEE 1514
G + C+ E
Sbjct: 800 GDGLN-CEPE 808
Score = 54.0 bits (124), Expect = 1e-05
Identities = 52/202 (25%), Positives = 74/202 (36%), Gaps = 36/202 (17%)
Query: 467 TGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPR 526
TG C C +SG C C G Y + C+C D G C C G+ G
Sbjct: 10 TGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGD--GSCDCDVGWRGVH 67
Query: 527 CDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY- 585
CD + NC+ T TS NCLTN G +C+ G+
Sbjct: 68 CDNATT--------------EDNCNGTCHTS--------ANCLTNSDGTASCKCAAGFQG 105
Query: 586 KYPDCLSCN-CDVS-GSIGSTCD------DNGLCHCKSNF--DGAKCDTCREQFYNYPAC 635
C + N C++S G + D +C CK+ + DG C N+ C
Sbjct: 106 NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGC 165
Query: 636 EECNCDPRGVTASFAGCGSVPA 657
++ N + + A C +PA
Sbjct: 166 DK-NAECTQTGPNQAACNCLPA 186
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 31/180 (17%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
C GY+G +C+ C A C++ G+C+ C G C+ C P F D
Sbjct: 591 CCKGYFG-RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 649
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNR 1482
C C C+ G + + SG+C C G CD P C+
Sbjct: 650 ----CLPCGCSDHGQCDDGI---TGSGQCLCETGWTGPSCD----TQAVLPAVCTPPCSA 698
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK-CFCFGKTTRCSSS 1541
H T C +N C C + G TC F QD+ GC K C K T+ S S
Sbjct: 699 HAT----CKENNT-CECNLDYEGDGI-TCTVVDFCKQDNG--GCAKVARCSQKGTKVSCS 750
Score = 49.2 bits (112), Expect = 3e-04
Identities = 36/128 (28%), Positives = 46/128 (35%), Gaps = 11/128 (8%)
Query: 1935 FGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCT----PCNCG-IASESTQCD 1989
FG +D TG C C G G C+ C +G++ C+ CN G + S CD
Sbjct: 4 FGWSD---GTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCD 60
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWN--YTKDGCDHCNCNTGY-SVGFMCNATGQCECLP 2046
C T C+ N DG C C G+ G +C A CE
Sbjct: 61 VGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISN 120
Query: 2047 GVIGEKCD 2054
G K D
Sbjct: 121 GGCSAKAD 128
Score = 46.8 bits (106), Expect = 0.001
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 33/140 (23%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD---VNTGICLNCADNTIGD 1791
EC+C + G +CE C G + P C+PC C+ H QCD +G CL C G
Sbjct: 626 ECKCNTGFNGTACEMCWPGRFG-PD--CLPCGCSDHG-QCDDGITGSGQCL-CETGWTGP 680
Query: 1792 HCE-------FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS----CD--------- 1831
C+ C AT ++ C C + Y + + C
Sbjct: 681 SCDTQAVLPAVCTPPCSAHATC---KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKV 737
Query: 1832 --LSENGSLISCNCQPGYGG 1849
S+ G+ +SC+CQ GY G
Sbjct: 738 ARCSQKGTKVSCSCQKGYKG 757
Score = 46.4 bits (105), Expect = 0.002
Identities = 65/261 (24%), Positives = 90/261 (34%), Gaps = 35/261 (13%)
Query: 376 SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKS 435
+G CEC F C +C G + + C+C ++G + DG C C + G
Sbjct: 10 TGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VHGRCNQG-PLGDGSCDCDVGWRGVH 67
Query: 436 CEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKY--SGRTCNQCQAGYYNYPT 493
C D + + N C+T + D T C C + + +G C A +
Sbjct: 68 C----DNATTEDNCNGTCHTSANCLTNSDG-TASCKCAAGFQGNGTICTAINACEISNGG 122
Query: 494 CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQC-VPCNCDP 552
C D T P C CKAG+ G CL L C C
Sbjct: 123 CS-AKADCKRTTPG-----RRVCTCKAGYTGDGI-VCLE--INPCLENHGGCDKNAECTQ 173
Query: 553 TGSTSTSCSADGKCNCLTNF--GGAQCDQCSPGYYKYPDCLS-CNCDVSGSIGSTCDDNG 609
TG + CNCL + G C + K C C+ +G + TC
Sbjct: 174 TGPNQAA------CNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCT--- 224
Query: 610 LCHCKSNFDGAKCDTCREQFY 630
CK N+ G TCR Y
Sbjct: 225 ---CKPNYIGDGF-TCRGSIY 241
Score = 43.6 bits (98), Expect = 0.014
Identities = 48/181 (26%), Positives = 64/181 (35%), Gaps = 24/181 (13%)
Query: 606 DDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPAG---ELCQ 662
D G+C C F G C+TC E Y + C+C G GS
Sbjct: 8 DGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVH 67
Query: 663 CKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLA----GTL-NSLGACNTKSGQCV-- 715
C + CN N N G C C GT+ ++ AC +G C
Sbjct: 68 CDNATTEDNCNGTCHTSANCLT-NSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAK 126
Query: 716 --CKQHVGERQCDQCLDGFYRLQTNDVFGCTECD-C-DIGGSIDNNCDKT-TG----QCH 766
CK+ R+ C G+ T D C E + C + G D N + T TG C+
Sbjct: 127 ADCKRTTPGRRVCTCKAGY----TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACN 182
Query: 767 C 767
C
Sbjct: 183 C 183
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/225 (26%), Positives = 81/225 (36%), Gaps = 38/225 (16%)
Query: 576 QCDQCSPGYYKYPDCLSCN------CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
Q +C GY+ DC +C C+ G G C C + F+G C+ C
Sbjct: 587 QIPRCCKGYFGR-DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 645
Query: 630 YNYPACEECNCDPR-----GVTAS-FAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ P C C C G+T S C + G C + V +C + +
Sbjct: 646 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQ-AVLPAVCTPPCSAHATCK 703
Query: 684 EYNPFGCEQCNCNLAG---TLNSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ 736
E N CE CN + G T + C +G C C Q + C C G+
Sbjct: 704 ENNT--CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC-SCQKGY---- 755
Query: 737 TNDVFGCTECD-CD---IGGSIDNNCDKTTG----QCHCHSRVEG 773
D CTE D C GG ++ K TG +C C S G
Sbjct: 756 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 800
Score = 41.5 bits (93), Expect = 0.056
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
CD F D G+CV P C R + L P + +C
Sbjct: 531 CDTFTTFDASGECGSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLV 585
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGE 2051
RC KG G+ C C G D CN N G + +ATG+C+C G G
Sbjct: 586 IQIPRCCKGYFGRDCQACPGG-----PDA--PCN-NRGVCLD-QYSATGECKCNTGFNGT 636
Query: 2052 KCDRCPERWVLIPQEGCLECDSCTD 2076
C+ C W CL C C+D
Sbjct: 637 ACEMC---WPGRFGPDCLPC-GCSD 657
Score = 37.5 bits (83), Expect = 0.90
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 8/70 (11%)
Query: 1448 SGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQ---NTAQCYCKTNVR 1504
+G C C E G C+ C G Y C+C HG C+Q C C R
Sbjct: 10 TGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VHGR----CNQGPLGDGSCDCDVGWR 64
Query: 1505 GQACDTCKEE 1514
G CD E
Sbjct: 65 GVHCDNATTE 74
>AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein.
Length = 2551
Score = 75.4 bits (177), Expect = 4e-12
Identities = 65/240 (27%), Positives = 94/240 (39%), Gaps = 39/240 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + G +CE C EG Y + C +G +Q + G C +C G HC+
Sbjct: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSC-VHGRCNQGPLGDGSC-DCDVGWRGVHCDN 1429
Query: 1796 CMSGYHGDATVGTPRDCLI-------CACPMPYPSNNFAL----SCDLSENGSLISCNCQ 1844
+ + + T T +CL C C + N +C++S G +C+
Sbjct: 1430 ATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 1489
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP--QDPGSCDSINGDCLKCV 1902
G R C AGY G G C INP ++ G CD N +C +
Sbjct: 1490 RTTPGRRVCTCKAGYTG--------DGIVCL------EINPCLENHGGCDK-NAECTQTG 1534
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACI-----CDEFGMAD-CDSTTGTCVCRPGVIGE 1956
N AACN C P + GD C+ C EF + + TC C+P IG+
Sbjct: 1535 PNQ--AACN-CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGD 1591
Score = 69.7 bits (163), Expect = 2e-10
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 529 QCLSGYYMQVLGRERQCVP----CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
+C GY+ GR+ Q P C+ G SA G+C C T F G C+ C PG
Sbjct: 1949 RCCKGYF----GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 585 YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT 624
+ PDCL C C G +G C C++ + G CDT
Sbjct: 2005 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 2043
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/99 (37%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 1414 CKPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYA 1471
CK Y F D Q G D CN GV +Q +G+C C G C+ C PG +
Sbjct: 1951 CKGY-FGRDCQACPGGPDAPCNNRGVCLDQYSA---TGECKCNTGFNGTACEMCWPGRFG 2006
Query: 1472 FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
PDC C C+ HG D + QC C+T G +CDT
Sbjct: 2007 -PDCLPCGCSDHGQCDDGI-TGSGQCLCETGWTGPSCDT 2043
Score = 64.9 bits (151), Expect = 5e-09
Identities = 44/140 (31%), Positives = 55/140 (39%), Gaps = 14/140 (10%)
Query: 518 CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
C G GP C +C G G PCN GS + +G C+C FGG C
Sbjct: 100 CCPGRWGPDCIECPGG-----AGS-----PCN--GRGSCAEGMEGNGTCSCQEGFGGTAC 147
Query: 578 DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE 636
+ C+ P C S CNC V G S D +G C C S + G KCD + E
Sbjct: 148 ETCADDNLFGPSCSSVCNC-VHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPE 206
Query: 637 ECNCDPRGVTASFAGCGSVP 656
C P + C +P
Sbjct: 207 NSRCSPSTEDENKLECKCLP 226
Score = 64.9 bits (151), Expect = 5e-09
Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 50/246 (20%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPED---TDLHTGDYCKP-----CNCS---GNI 1883
NG+ + C C G+ G CE C G YGI D + +H P C+C +
Sbjct: 1367 NGTGV-CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGV 1425
Query: 1884 NPQDPGSCDSINGDC---LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG---M 1937
+ + + D+ NG C C+ N+ G A CA GF G+ AC G
Sbjct: 1426 HCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAK 1485
Query: 1938 ADCDSTT---GTCVCRPGVIGE-----KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
ADC TT C C+ G G+ + + C +H G C +E TQ
Sbjct: 1486 ADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGG-----------CDKNAECTQTG 1534
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ----CECL 2045
+ C C TG C TK+G G S +CN TGQ C C
Sbjct: 1535 PNQAACNCLPAYTG-DGKVCTLINVCLTKNG--------GCSEFAICNHTGQVERTCTCK 1585
Query: 2046 PGVIGE 2051
P IG+
Sbjct: 1586 PNYIGD 1591
Score = 64.5 bits (150), Expect = 7e-09
Identities = 78/272 (28%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 483 QCQAGYYNYPTCKPC--NCDTSGTEPSIC-DDVSGQ--CICKAGFGGPRCDQCLSGYYMQ 537
+C AG++ P C+PC N IC D V+G C C GF G C+ C G Y
Sbjct: 1335 ECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
Query: 538 VLGRERQCV--PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
+ CV CN P G DG C+C + G CD + D + C
Sbjct: 1394 HCDQACSCVHGRCNQGPLG--------DGSCDCDVGWRGVHCDNATT-----EDNCNGTC 1440
Query: 596 DVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC-GS 654
S + + D C C + F G C ACE N G ++ A C +
Sbjct: 1441 HTSANCLTNSDGTASCKCAAGFQG-NGTICTA----INACEISN----GGCSAKADCKRT 1491
Query: 655 VPAGELCQCKDRV--QGRICNDCKPLYWN------LQEYNPFGCEQ--CNCNLAGT---- 700
P +C CK G +C + P N E G Q CNC A T
Sbjct: 1492 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGK 1551
Query: 701 -LNSLGACNTKSGQC----VCKQHVG--ERQC 725
+ C TK+G C +C H G ER C
Sbjct: 1552 VCTLINVCLTKNGGCSEFAIC-NHTGQVERTC 1582
Score = 63.7 bits (148), Expect = 1e-08
Identities = 60/195 (30%), Positives = 76/195 (38%), Gaps = 42/195 (21%)
Query: 1913 CAPGFYGDAIFSKNCTACI------CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDH 1965
C G++G ++C AC C+ G+ D S TG C C G G C+ C P
Sbjct: 1950 CCKGYFG-----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 1966 WGLNTGLGCTPCNCGIASESTQCDDD---NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+G + C PC C S+ QCDD +GQC C G TG CD A T
Sbjct: 2005 FGPD----CLPCGC---SDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSA 2057
Query: 2023 H--------CNCNTGY-SVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP---QEG--- 2067
H C CN Y G C C+ G K RC ++ + Q+G
Sbjct: 2058 HATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCA-KVARCSQKGTKVSCSCQKGYKG 2116
Query: 2068 ----CLECDSCTDAL 2078
C E D C D L
Sbjct: 2117 DGHSCTEIDPCADGL 2131
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/321 (26%), Positives = 115/321 (35%), Gaps = 55/321 (17%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDE-LDVCQPCQCDPHFSTGNCEEESGRCE 380
GG+C C C T P RW + V Q C + F E R
Sbjct: 1887 GGRCDTFTTFDASGECGSCVNT---PSCPRWSKPKGVKQKCLYNLPFKRNL---EGCRER 1940
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCT------CNLNGTEGEHCTPTDGLCPCKYNYAGK 434
C Q P C GYF +C+ C CN G + + T G C C + G
Sbjct: 1941 CSLVIQIPRCCK---GYFGR-DCQACPGGPDAPCNNRGVCLDQYSAT-GECKCNTGFNGT 1995
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLT--GDCTCKSKYSGRTCNQ-------CQ 485
+CE+C G + P+C C C+ G D +T G C C++ ++G +C+ C
Sbjct: 1996 ACEMCWPGRFGPDCLPCGCSDHGQCD---DGITGSGQCLCETGWTGPSCDTQAVLPAVCT 2052
Query: 486 AGYYNYPTCK-----PCNCDTSG-----TEPSICDDVSGQC--ICKAGFGGPRCD-QCLS 532
+ TCK CN D G T C +G C + + G + C
Sbjct: 2053 PPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQK 2112
Query: 533 GYYMQVLGRERQCVPCNCDP-TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
GY G C DP + C C +T G +C +C Y D L
Sbjct: 2113 GY----KGDGHSCT--EIDPCADGLNGGCHEHATCK-MTGPGKHKC-ECKSHY--VGDGL 2162
Query: 592 SCNCDVSGSIGSTCDDNGLCH 612
+C + I DNG CH
Sbjct: 2163 NCEPE-QLPIDRCLQDNGQCH 2182
Score = 60.9 bits (141), Expect = 8e-08
Identities = 61/235 (25%), Positives = 90/235 (38%), Gaps = 41/235 (17%)
Query: 439 CEDGYYSPECKNCECNT--VGSVSYVC-DKL--TGDCTCKSKYSGRTCNQCQAGYYNYPT 493
C G++ P+C+ C N V + +C D + TG C C +SG C C G Y
Sbjct: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395
Query: 494 CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
+ C+C D G C C G+ G CD + NC+ T
Sbjct: 1396 DQACSCVHGRCNQGPLGD--GSCDCDVGWRGVHCDNATT--------------EDNCNGT 1439
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN-CDVS-GSIGSTCD---- 606
TS NCLTN G +C+ G+ C + N C++S G + D
Sbjct: 1440 CHTS--------ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT 1491
Query: 607 --DNGLCHCKSNF--DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPA 657
+C CK+ + DG C N+ C++ N + + A C +PA
Sbjct: 1492 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDK-NAECTQTGPNQAACNCLPA 1545
Score = 59.3 bits (137), Expect = 3e-07
Identities = 64/259 (24%), Positives = 89/259 (34%), Gaps = 35/259 (13%)
Query: 381 CRPEFQPPDCSSCAYG--YFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI 438
CR ++ P C +G + P CN G+ E +G C C+ + G +CE
Sbjct: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEG-NGTCSCQEGFGGTACET 149
Query: 439 C-EDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC 497
C +D + P C + CN V V G C C S Y+G C++ P C
Sbjct: 150 CADDNLFGPSCSSV-CNCVHGVCNSGLDGDGTCECYSAYTGPKCDK------PIPECAAL 202
Query: 498 NC-DTSGTEPSICDDVSGQCICKAGF--GGPRCDQ--------CLSGYYMQVLGRERQCV 546
C + S PS D+ +C C + G CD C + LG R
Sbjct: 203 LCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSC 262
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC---------DV 597
C G D C NFG + + Y P C C V
Sbjct: 263 TCQEGYRGDGQVCLPVD---PCQINFGNCP-TKSTVCKYDGPGQSHCECKEHYQNFVPGV 318
Query: 598 SGSIGSTCDDNGLCHCKSN 616
S+ C + CH +N
Sbjct: 319 GCSMTDICKSDNPCHRNAN 337
Score = 56.0 bits (129), Expect = 2e-06
Identities = 56/214 (26%), Positives = 80/214 (37%), Gaps = 24/214 (11%)
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACI 1931
++C P +G D S +I +C C N G C ++ ++C
Sbjct: 17 NFCSPAETTGQARRCDRKSLLTIRTECRSCALNL-GVKCPDGYTMITSGSVGVRDCRYT- 74
Query: 1932 CDEFGMADCDSTTGTC--VCRPGVIGEKCDRCAPDHWGLNT----GLGCTPCNC-GIASE 1984
F + + C +CR + RC P WG + G +PCN G +E
Sbjct: 75 ---FEVRTYSLSLPGCRHICRKDYLQP---RCCPGRWGPDCIECPGGAGSPCNGRGSCAE 128
Query: 1985 STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATGQCE 2043
+ NG C C +G G C+ CA N C CNC G + + G CE
Sbjct: 129 GME---GNGTCSCQEGFGGTACETCADD--NLFGPSCSSVCNCVHGVCNSGL-DGDGTCE 182
Query: 2044 CLPGVIGEKCDR-CPERWVLIPQEGCLECDSCTD 2076
C G KCD+ PE L+ E C T+
Sbjct: 183 CYSAYTGPKCDKPIPECAALLCPENS-RCSPSTE 215
Score = 55.2 bits (127), Expect = 4e-06
Identities = 72/281 (25%), Positives = 100/281 (35%), Gaps = 35/281 (12%)
Query: 393 CAYGYFDYPNCKPC------TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
C G+F P C+PC C NG + T G+C C ++G +CE C +G Y
Sbjct: 1336 CCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGT-GVCECGEGFSGTACETCTEGKYGI 1393
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC-KPCNCDTSGTE 505
C C+ V G C C + G C+ TC NC T+
Sbjct: 1394 HCDQA-CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN--- 1449
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL-GRERQCVPCNCDPTGSTSTSCSA-- 562
D + C C AGF G C + ++ G C G +C A
Sbjct: 1450 ----SDGTASCKCAAGFQG-NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY 1504
Query: 563 --DG----KCN-CLTNFGGAQCDQCSPGYYKYPDCLSCNC-DVSGSIGSTCDDNGLCHCK 614
DG + N CL N GG CD+ + P+ +CNC G C +C K
Sbjct: 1505 TGDGIVCLEINPCLENHGG--CDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK 1562
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSV 655
N ++ C + C C P + F GS+
Sbjct: 1563 -NGGCSEFAICN---HTGQVERTCTCKPNYIGDGFTCRGSI 1599
Score = 55.2 bits (127), Expect = 4e-06
Identities = 67/246 (27%), Positives = 91/246 (36%), Gaps = 49/246 (19%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C GY G RDC C P NN + D + + C C G+ G CE C
Sbjct: 1950 CCKGYFG-------RDCQACPGGPDAPCNNRGVCLD--QYSATGECKCNTGFNGTACEMC 2000
Query: 1856 AAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD---SINGDCLKCVNNTAGAACN- 1911
G +G P+ C PC CS D G CD + +G CL C G +C+
Sbjct: 2001 WPGRFG-PD---------CLPCGCS------DHGQCDDGITGSGQCL-CETGWTGPSCDT 2043
Query: 1912 ------LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG-EKCDRCAPD 1964
+C P A +N T C C+ D + T C+ G K RC+
Sbjct: 2044 QAVLPAVCTPPCSAHATCKENNT-CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
T + C+ C G + C + + CA G+ G C + A T G C
Sbjct: 2103 ----GTKVSCS-CQKGYKGDGHSCTEID---PCADGLNG-GCHEHAT--CKMTGPGKHKC 2151
Query: 2025 NCNTGY 2030
C + Y
Sbjct: 2152 ECKSHY 2157
Score = 55.2 bits (127), Expect = 4e-06
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 38/190 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD----NGMCICPKNVEGENCD 1412
G+C C G C C G +G P+C PC C CDD +G C+C G +CD
Sbjct: 1984 GECKCNTGFNGTACEMCWPGRFG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD 2042
Query: 1413 R-------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ------CEADSGKCA--CRENV 1457
C P + + C CN L G+ + C+ D+G CA R +
Sbjct: 2043 TQAVLPAVCTPPCSAHATCKENNTCECN-LDYEGDGITCTVVDFCKQDNGGCAKVARCSQ 2101
Query: 1458 RG-RVCDHCVPGHYAFPDCYQCT------------CNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G +V C G+ D + CT C+ H T + +C CK++
Sbjct: 2102 KGTKVSCSCQKGYKG--DGHSCTEIDPCADGLNGGCHEHATC-KMTGPGKHKCECKSHYV 2158
Query: 1505 GQACDTCKEE 1514
G + C+ E
Sbjct: 2159 GDGLN-CEPE 2167
Score = 53.6 bits (123), Expect = 1e-05
Identities = 68/263 (25%), Positives = 97/263 (36%), Gaps = 39/263 (14%)
Query: 518 CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
C GF GP C+QC G+ C G + S +G C C F G+QC
Sbjct: 728 CCKGFYGPDCNQCPGGFSNP------------CSGNGQCADSLGGNGTCICEEGFQGSQC 775
Query: 578 DQCSPGYYKYPDC-LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNY-PAC 635
CS P C C C V G+ + D +G C + DG+ C +Q P
Sbjct: 776 QFCSDPNKYGPRCNKKCLC-VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV 834
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ-CN 694
+ C+ T ++ G+ A +C+ G +C++ P P GC +
Sbjct: 835 QFCHIH---ATCEYSN-GT--ASCICKAGYEGDGTLCSEMDP----CTGLTPGGCSRNAE 884
Query: 695 CNLAGTLNSLGACN---TKSGQ-CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD- 749
C GT C T +G+ C + C D L G EC+C
Sbjct: 885 CIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP--GQNECECKK 942
Query: 750 --IGGSID----NNCDKTTGQCH 766
G ID +C + TG+CH
Sbjct: 943 GFRGNGIDCEPITSCLEQTGKCH 965
Score = 52.0 bits (119), Expect = 4e-05
Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 17/140 (12%)
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD------QCSPGYYKYPDCLSCN------ 594
P N +PT + C G+ L + C+ +C G+Y PDC C
Sbjct: 689 PANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYG-PDCNQCPGGFSNP 747
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EECNCDPRGVTASFAGCG 653
C +G + NG C C+ F G++C C + P C ++C C G
Sbjct: 748 CSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDG 807
Query: 654 SVPAGELCQCKDRVQGRICN 673
+ G C+D GR+C+
Sbjct: 808 ACLTG---TCRDGSAGRLCD 824
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/203 (24%), Positives = 65/203 (32%), Gaps = 21/203 (10%)
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--KCVNNTAGAA 1909
C C+ Y+ T + C SG G N KC G
Sbjct: 677 CVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPD 736
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCA-PDHWGL 1968
CN C GF + C AD GTC+C G G +C C+ P+ +G
Sbjct: 737 CNQCPGGFSNPCSGNGQC----------ADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP 786
Query: 1969 NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
C C G + D C G G+ CD+ + Y + H C
Sbjct: 787 RCNKKCL-CVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCE- 844
Query: 2029 GYSVGFMCNATGQCECLPGVIGE 2051
YS N T C C G G+
Sbjct: 845 -YS-----NGTASCICKAGYEGD 861
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 31/180 (17%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
C GY+G +C+ C A C++ G+C+ C G C+ C P F D
Sbjct: 1950 CCKGYFG-RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNR 1482
C C C+ G + + SG+C C G CD P C+
Sbjct: 2009 ----CLPCGCSDHGQCDDGI---TGSGQCLCETGWTGPSCD----TQAVLPAVCTPPCSA 2057
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK-CFCFGKTTRCSSS 1541
H T C +N C C + G TC F QD+ GC K C K T+ S S
Sbjct: 2058 HAT----CKENNT-CECNLDYEGDGI-TCTVVDFCKQDNG--GCAKVARCSQKGTKVSCS 2109
Score = 50.8 bits (116), Expect = 9e-05
Identities = 72/285 (25%), Positives = 99/285 (34%), Gaps = 41/285 (14%)
Query: 358 CQPCQCDPH---FSTGNCEEE---SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLN 411
CQPC + F G C + +G CEC F C +C G + + C+C ++
Sbjct: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 1403
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + DG C C + G C D + + N C+T + D T C
Sbjct: 1404 GRCNQG-PLGDGSCDCDVGWRGVHC----DNATTEDNCNGTCHTSANCLTNSDG-TASCK 1457
Query: 472 CKSKY--SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ 529
C + + +G C A + C D T P C CKAG+ G
Sbjct: 1458 CAAGFQGNGTICTAINACEISNGGCS-AKADCKRTTPG-----RRVCTCKAGYTGDGI-V 1510
Query: 530 CLSGYYMQVLGRERQC-VPCNCDPTGSTSTSCSADGKCNCLTNF--GGAQCDQCSPGYYK 586
CL L C C TG + CNCL + G C + K
Sbjct: 1511 CLE--INPCLENHGGCDKNAECTQTGPNQAA------CNCLPAYTGDGKVCTLINVCLTK 1562
Query: 587 YPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY 630
C C+ +G + TC CK N+ G TCR Y
Sbjct: 1563 NGGCSEFAICNHTGQVERTCT------CKPNYIGDGF-TCRGSIY 1600
Score = 50.4 bits (115), Expect = 1e-04
Identities = 69/314 (21%), Positives = 102/314 (32%), Gaps = 47/314 (14%)
Query: 1737 QCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
+C + + G C QC P GF PC NG G C+ C + G C+FC
Sbjct: 727 KCCKGFYGPDCNQC-------PGGFSNPCSGNGQCADSLGGNGTCI-CEEGFQGSQCQFC 778
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC- 1855
C+ C S+ L+ + + C+ Q G ++C
Sbjct: 779 SDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCH 838
Query: 1856 --AAGYYGIPEDTDLHTGDYCKPCNCSGNINP---QDPGSCDSINGDCLKCVNNTAGAAC 1910
A Y + + Y ++P PG C S N +C+K T C
Sbjct: 839 IHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC-SRNAECIK--TGTGTHTC 895
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
+C G+ G+ C+ G C PG +C+ C G
Sbjct: 896 -VCQQGWTGNGRDCSEINNCLLPSAG--GCHDNASCLYVGPG--QNECE-CKKGFRG--N 947
Query: 1971 GLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGY 2030
G+ C P T C + G+C C ++G W+ C C GY
Sbjct: 948 GIDCEPI--------TSCLEQTGKCHPL-----ASCQSTSSGVWS--------CVCQEGY 986
Query: 2031 -SVGFMCNATGQCE 2043
GF+C E
Sbjct: 987 EGDGFLCYGNAAVE 1000
Score = 48.4 bits (110), Expect = 5e-04
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 36/192 (18%)
Query: 1320 GLCREAMFSITSEYNSGA-----RPCLCD--FMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
G CR +T + + + R C+ FMG L G Q C VI R C A
Sbjct: 1282 GRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTL---FIGCQPKCVRTVITRECCA 1338
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
G++G P C+PC + +C NG+C+ C + G C+ C +
Sbjct: 1339 ---GFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
Query: 1423 VQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY---QC 1478
CD C+C V G Q G C C RG CD+ C+ C
Sbjct: 1395 ----CDQACSC----VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC 1446
Query: 1479 TCNRHGTTYDVC 1490
N GT C
Sbjct: 1447 LTNSDGTASCKC 1458
Score = 48.0 bits (109), Expect = 6e-04
Identities = 46/167 (27%), Positives = 59/167 (35%), Gaps = 24/167 (14%)
Query: 1373 CRTGYYGFPNCRPCH------CPSTAICDD----NGMCICPKNVEGENCDRCK-PYTFNF 1421
C G+YG P+C C C C D NG CIC + +G C C P +
Sbjct: 728 CCKGFYG-PDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG- 785
Query: 1422 DVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCN 1481
R C C G N++ + CR+ GR+CD P Y C+
Sbjct: 786 --PRCNKKCLC-VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--CGP--YVQFCH 838
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK 1528
H T TA C CK G T E P GC++
Sbjct: 839 IHATC--EYSNGTASCICKAGYEGDG--TLCSEMDPCTGLTPGGCSR 881
Score = 47.2 bits (107), Expect = 0.001
Identities = 58/219 (26%), Positives = 77/219 (35%), Gaps = 31/219 (14%)
Query: 568 CLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCRE 627
C F G QC C PG + C + G G+ G+C C F G C+TC E
Sbjct: 1336 CCAGFFGPQCQPC-PGNAQNV-CFGNGICLDGVNGT-----GVCECGEGFSGTACETCTE 1388
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAG---ELCQCKDRVQGRICNDCKPLYWNLQE 684
Y + C+C G GS C + CN N
Sbjct: 1389 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLT 1448
Query: 685 YNPFGCEQCNCNLA----GTL-NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRL 735
N G C C GT+ ++ AC +G C CK+ R+ C G+
Sbjct: 1449 -NSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--- 1504
Query: 736 QTNDVFGCTECD-C-DIGGSIDNNCDKT-TG----QCHC 767
T D C E + C + G D N + T TG C+C
Sbjct: 1505 -TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC 1542
Score = 46.8 bits (106), Expect = 0.001
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 33/140 (23%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD---VNTGICLNCADNTIGD 1791
EC+C + G +CE C G + P C+PC C+ H QCD +G CL C G
Sbjct: 1985 ECKCNTGFNGTACEMCWPGRFG-PD--CLPCGCSDHG-QCDDGITGSGQCL-CETGWTGP 2039
Query: 1792 HCE-------FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS----CD--------- 1831
C+ C AT ++ C C + Y + + C
Sbjct: 2040 SCDTQAVLPAVCTPPCSAHATC---KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKV 2096
Query: 1832 --LSENGSLISCNCQPGYGG 1849
S+ G+ +SC+CQ GY G
Sbjct: 2097 ARCSQKGTKVSCSCQKGYKG 2116
Score = 46.4 bits (105), Expect = 0.002
Identities = 78/303 (25%), Positives = 108/303 (35%), Gaps = 47/303 (15%)
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C + P C YG P+C C G P G C + G ICE
Sbjct: 719 CNATVKIPKCCKGFYG----PDCNQCP-------GGFSNPCSGNGQCADSLGGNGTCICE 767
Query: 441 DGYYSPECKNC-ECNTVG-SVSYVCDKLTGDCTCKSKYSGR----TCNQCQAGYYNYPTC 494
+G+ +C+ C + N G + C + G C + G TC AG
Sbjct: 768 EGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQT 827
Query: 495 KPCNCDTSGTE-PSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
C + C+ +G CICKAG+ G D L + PC
Sbjct: 828 SACGPYVQFCHIHATCEYSNGTASCICKAGYEG---DGTLCS----------EMDPC--- 871
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCNCDVSGSIGSTCDDNGL 610
TG T CS + +C T G C C G+ DC N + S G C DN
Sbjct: 872 -TGLTPGGCSRNAEC-IKTGTGTHTC-VCQQGWTGNGRDCSEINNCLLPSAGG-CHDNAS 927
Query: 611 CHCKSNFDGAKCDTCREQFY-NYPACEE-CNC-DPRGVTASFAGCGSVPAGE-LCQCKDR 666
C +C+ C++ F N CE +C + G A C S +G C C++
Sbjct: 928 CLYVGPGQN-ECE-CKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEG 985
Query: 667 VQG 669
+G
Sbjct: 986 YEG 988
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/184 (25%), Positives = 64/184 (34%), Gaps = 27/184 (14%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRP-CHCPSTAIC----DDNGMCICPKNVEGENC 1411
G C C+ G C C P+C C+C +C D +G C C G C
Sbjct: 134 GTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH-GVCNSGLDGDGTCECYSAYTGPKC 192
Query: 1412 DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE------ADSGKCACRENVRGRVCDHC 1465
D+ P ++ C+P N+L+C+ D C ++C
Sbjct: 193 DKPIPECAALLCP---ENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPH 249
Query: 1466 VPGHYAFPDCYQCTCNR--HG-----TTYDVCDQNTAQC-----YCKTNVRGQACDTCKE 1513
Y P+ + CTC G D C N C CK + GQ+ CKE
Sbjct: 250 AHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKE 309
Query: 1514 EYFN 1517
Y N
Sbjct: 310 HYQN 313
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 15/97 (15%)
Query: 690 CEQCNCNLAGTLNSLGACNTK---SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFG--CT 744
C +C N G+C +G C C++ G C+ C D +++FG C+
Sbjct: 109 CIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCAD-------DNLFGPSCS 161
Query: 745 E-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
C+C + G ++ D G C C+S G +CD+PI
Sbjct: 162 SVCNC-VHGVCNSGLDGD-GTCECYSAYTGPKCDKPI 196
Score = 43.6 bits (98), Expect = 0.014
Identities = 66/257 (25%), Positives = 86/257 (33%), Gaps = 61/257 (23%)
Query: 1811 DCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
DC+ C P N SC G+ +C+CQ G+GG CE CA D +L
Sbjct: 108 DCIECPGGAGSPCNGRG-SCAEGMEGNG-TCSCQEGFGGTACETCA--------DDNLFG 157
Query: 1871 GDYCKPCNCSGNINPQDPGSCDS-INGD-CLKCVNNTAGAACNLCAPGFYGDAIFSKNCT 1928
CNC G C+S ++GD +C + G C+ P C
Sbjct: 158 PSCSSVCNCV-------HGVCNSGLDGDGTCECYSAYTGPKCDKPIP----------ECA 200
Query: 1929 ACICDEFGMADC---DSTTGTCVCRPGVIGE--KCDRCAPDHWGLNTGLGCTPCNCGIAS 1983
A +C E D C C P G+ CD P C C +
Sbjct: 201 ALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP----------CLRKICHPHA 250
Query: 1984 ESTQCDDDNGQCRCAKGV--TGKQC---DQCAAGFWN---------YTKDGCDHCNCNTG 2029
T + C C +G G+ C D C F N Y G HC C
Sbjct: 251 HCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH 310
Query: 2030 YS---VGFMCNATGQCE 2043
Y G C+ T C+
Sbjct: 311 YQNFVPGVGCSMTDICK 327
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/225 (26%), Positives = 81/225 (36%), Gaps = 38/225 (16%)
Query: 576 QCDQCSPGYYKYPDCLSCN------CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
Q +C GY+ DC +C C+ G G C C + F+G C+ C
Sbjct: 1946 QIPRCCKGYFGR-DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 630 YNYPACEECNCDPR-----GVTAS-FAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ P C C C G+T S C + G C + V +C + +
Sbjct: 2005 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQ-AVLPAVCTPPCSAHATCK 2062
Query: 684 EYNPFGCEQCNCNLAG---TLNSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ 736
E N CE CN + G T + C +G C C Q + C C G+
Sbjct: 2063 ENNT--CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC-SCQKGY---- 2114
Query: 737 TNDVFGCTECD-CD---IGGSIDNNCDKTTG----QCHCHSRVEG 773
D CTE D C GG ++ K TG +C C S G
Sbjct: 2115 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 2159
Score = 41.5 bits (93), Expect = 0.056
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
CD F D G+CV P C R + L P + +C
Sbjct: 1890 CDTFTTFDASGECGSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLV 1944
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGE 2051
RC KG G+ C C G D CN N G + +ATG+C+C G G
Sbjct: 1945 IQIPRCCKGYFGRDCQACPGG-----PDA--PCN-NRGVCLD-QYSATGECKCNTGFNGT 1995
Query: 2052 KCDRCPERWVLIPQEGCLECDSCTD 2076
C+ C W CL C C+D
Sbjct: 1996 ACEMC---WPGRFGPDCLPC-GCSD 2016
Score = 39.5 bits (88), Expect = 0.22
Identities = 38/146 (26%), Positives = 49/146 (33%), Gaps = 13/146 (8%)
Query: 340 CRPTYYRPY---GKRWDELDVCQPCQCDPHFSTGNCEEE---SGRCECRPEFQPPDCSSC 393
CR Y +P G+ + C P G+C E +G C C+ F C +C
Sbjct: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
Query: 394 AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCEC 453
A P+C CN DG C C Y G C+ PEC C
Sbjct: 151 ADDNLFGPSCS-SVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD-----KPIPECAALLC 204
Query: 454 NTVGSVS-YVCDKLTGDCTCKSKYSG 478
S D+ +C C Y G
Sbjct: 205 PENSRCSPSTEDENKLECKCLPNYRG 230
Score = 39.5 bits (88), Expect = 0.22
Identities = 62/247 (25%), Positives = 88/247 (35%), Gaps = 47/247 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP----SGFCVPCQCNGHSDQCDVNTGICL--NCADNTI 1789
C C ++G C+ C++ + P CV CN D + G CL C D +
Sbjct: 764 CICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRID----SDGACLTGTCRDGSA 819
Query: 1790 GDHCEFCMSG-------YHGDATVGTPRDCLICACPMPYPSNNFALS----C-DLSENGS 1837
G C+ S H AT C C Y + S C L+ G
Sbjct: 820 GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC 879
Query: 1838 LISCNC-QPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
+ C + G G C C G+ G D C+ N G C N
Sbjct: 880 SRNAECIKTGTGTHTC-VCQQGWTGNGRD-----------CSEINNCLLPSAGGCHD-NA 926
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG----MADCDSTTG---TCVC 1949
CL C C GF G+ I + T+C+ ++ G +A C ST+ +CVC
Sbjct: 927 SCLYV--GPGQNECE-CKKGFRGNGIDCEPITSCL-EQTGKCHPLASCQSTSSGVWSCVC 982
Query: 1950 RPGVIGE 1956
+ G G+
Sbjct: 983 QEGYEGD 989
Score = 38.7 bits (86), Expect = 0.39
Identities = 41/152 (26%), Positives = 51/152 (33%), Gaps = 18/152 (11%)
Query: 1361 CKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFN 1420
C P G C C G G P C + NG C C + G C+ C N
Sbjct: 100 CCPGRWGPDCIECPGGA-GSPCNGRGSCAEGM--EGNGTCSCQEGFGGTACETCA--DDN 154
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTC 1480
CNC GV + L G C C G CD + P+C C
Sbjct: 155 LFGPSCSSVCNC-VHGVCNSGLD---GDGTCECYSAYTGPKCDKPI------PECAALLC 204
Query: 1481 NRHG-TTYDVCDQNTAQCYCKTNVRGQA--CD 1509
+ + D+N +C C N RG CD
Sbjct: 205 PENSRCSPSTEDENKLECKCLPNYRGDGKYCD 236
Score = 38.7 bits (86), Expect = 0.39
Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 11/94 (11%)
Query: 1427 CDDCNCNPLGVV-GNQLQCEA--DSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRH 1483
C C N V GN + + +G C C E G C+ C G Y C+C H
Sbjct: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 1403
Query: 1484 GTTYDVCDQ---NTAQCYCKTNVRGQACDTCKEE 1514
G C+Q C C RG CD E
Sbjct: 1404 GR----CNQGPLGDGSCDCDVGWRGVHCDNATTE 1433
Score = 37.9 bits (84), Expect = 0.68
Identities = 34/120 (28%), Positives = 47/120 (39%), Gaps = 20/120 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C + G +CE CA+ + PS C S C+ G+C + D GD
Sbjct: 136 CSCQEGFGGTACETCADDNLFGPS--C--------SSVCNCVHGVCNSGLD---GDGTCE 182
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C S Y G +C CP N S +E+ + + C C P Y G +YC
Sbjct: 183 CYSAYTGPKCDKPIPECAALLCP-----ENSRCS-PSTEDENKLECKCLPNYRGDG-KYC 235
Score = 36.7 bits (81), Expect = 1.6
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 8/56 (14%)
Query: 1465 CVPGHYAFPDCYQCT------CNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
C PG + PDC +C CN G+ + + N C C+ G AC+TC ++
Sbjct: 100 CCPGRWG-PDCIECPGGAGSPCNGRGSCAEGMEGN-GTCSCQEGFGGTACETCADD 153
Score = 35.9 bits (79), Expect = 2.8
Identities = 65/274 (23%), Positives = 90/274 (32%), Gaps = 40/274 (14%)
Query: 248 NLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE-PCNCHN--HTTEC---- 300
N + + +C GP CN+C GF Q D C C ++C
Sbjct: 720 NATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCS 779
Query: 301 ---TYDPEIDEKRLSL--DINGRYEGGGKCL--NCQHNTEGINCNKCRPTYYRPYGKRWD 353
Y P ++K L + N R + G CL C+ + G C+K + + PY +
Sbjct: 780 DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDK-QTSACGPYVQFCH 838
Query: 354 ELDVCQ------PCQCDPHF-STGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPC 406
C+ C C + G E C P CS A C
Sbjct: 839 IHATCEYSNGTASCICKAGYEGDGTLCSEMDPC---TGLTPGGCSRNAECIKTGTGTHTC 895
Query: 407 TCNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCEC------NTVGSV 459
C T G C+ + C AG + Y P CEC N +
Sbjct: 896 VCQQGWTGNGRDCSEINN---CLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCE 952
Query: 460 SYV-CDKLTGDC----TCKSKYSGRTCNQCQAGY 488
C + TG C +C+S SG CQ GY
Sbjct: 953 PITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
Score = 35.1 bits (77), Expect = 4.8
Identities = 21/80 (26%), Positives = 28/80 (35%), Gaps = 6/80 (7%)
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD--VC---DQNTAQCYCKTNVRGQACDTC 1511
VR + C G + P C C N + +C T C C G AC+TC
Sbjct: 1328 VRTVITRECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETC 1386
Query: 1512 KEEYFNLQDDNPDGCTKCFC 1531
E + + D C C
Sbjct: 1387 TEGKYGIHCDQACSCVHGRC 1406
Score = 34.3 bits (75), Expect = 8.4
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 9/63 (14%)
Query: 1996 RCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
+C KG G C+QC GF N G C + G G C C G G +C
Sbjct: 727 KCCKGFYGPDCNQCPGGFSN-PCSGNGQCADSLG--------GNGTCICEEGFQGSQCQF 777
Query: 2056 CPE 2058
C +
Sbjct: 778 CSD 780
>AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein.
Length = 2551
Score = 75.4 bits (177), Expect = 4e-12
Identities = 65/240 (27%), Positives = 94/240 (39%), Gaps = 39/240 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + G +CE C EG Y + C +G +Q + G C +C G HC+
Sbjct: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSC-VHGRCNQGPLGDGSC-DCDVGWRGVHCDN 1429
Query: 1796 CMSGYHGDATVGTPRDCLI-------CACPMPYPSNNFAL----SCDLSENGSLISCNCQ 1844
+ + + T T +CL C C + N +C++S G +C+
Sbjct: 1430 ATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 1489
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP--QDPGSCDSINGDCLKCV 1902
G R C AGY G G C INP ++ G CD N +C +
Sbjct: 1490 RTTPGRRVCTCKAGYTG--------DGIVCL------EINPCLENHGGCDK-NAECTQTG 1534
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACI-----CDEFGMAD-CDSTTGTCVCRPGVIGE 1956
N AACN C P + GD C+ C EF + + TC C+P IG+
Sbjct: 1535 PNQ--AACN-CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGD 1591
Score = 69.7 bits (163), Expect = 2e-10
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 529 QCLSGYYMQVLGRERQCVP----CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
+C GY+ GR+ Q P C+ G SA G+C C T F G C+ C PG
Sbjct: 1949 RCCKGYF----GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 585 YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT 624
+ PDCL C C G +G C C++ + G CDT
Sbjct: 2005 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 2043
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/99 (37%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 1414 CKPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYA 1471
CK Y F D Q G D CN GV +Q +G+C C G C+ C PG +
Sbjct: 1951 CKGY-FGRDCQACPGGPDAPCNNRGVCLDQYSA---TGECKCNTGFNGTACEMCWPGRFG 2006
Query: 1472 FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
PDC C C+ HG D + QC C+T G +CDT
Sbjct: 2007 -PDCLPCGCSDHGQCDDGI-TGSGQCLCETGWTGPSCDT 2043
Score = 64.9 bits (151), Expect = 5e-09
Identities = 44/140 (31%), Positives = 55/140 (39%), Gaps = 14/140 (10%)
Query: 518 CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
C G GP C +C G G PCN GS + +G C+C FGG C
Sbjct: 100 CCPGRWGPDCIECPGG-----AGS-----PCN--GRGSCAEGMEGNGTCSCQEGFGGTAC 147
Query: 578 DQCSPGYYKYPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACE 636
+ C+ P C S CNC V G S D +G C C S + G KCD + E
Sbjct: 148 ETCADDNLFGPSCSSVCNC-VHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPE 206
Query: 637 ECNCDPRGVTASFAGCGSVP 656
C P + C +P
Sbjct: 207 NSRCSPSTEDENKLECKCLP 226
Score = 64.9 bits (151), Expect = 5e-09
Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 50/246 (20%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPED---TDLHTGDYCKP-----CNCS---GNI 1883
NG+ + C C G+ G CE C G YGI D + +H P C+C +
Sbjct: 1367 NGTGV-CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGV 1425
Query: 1884 NPQDPGSCDSINGDC---LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG---M 1937
+ + + D+ NG C C+ N+ G A CA GF G+ AC G
Sbjct: 1426 HCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAK 1485
Query: 1938 ADCDSTT---GTCVCRPGVIGE-----KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
ADC TT C C+ G G+ + + C +H G C +E TQ
Sbjct: 1486 ADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGG-----------CDKNAECTQTG 1534
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ----CECL 2045
+ C C TG C TK+G G S +CN TGQ C C
Sbjct: 1535 PNQAACNCLPAYTG-DGKVCTLINVCLTKNG--------GCSEFAICNHTGQVERTCTCK 1585
Query: 2046 PGVIGE 2051
P IG+
Sbjct: 1586 PNYIGD 1591
Score = 64.5 bits (150), Expect = 7e-09
Identities = 78/272 (28%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 483 QCQAGYYNYPTCKPC--NCDTSGTEPSIC-DDVSGQ--CICKAGFGGPRCDQCLSGYYMQ 537
+C AG++ P C+PC N IC D V+G C C GF G C+ C G Y
Sbjct: 1335 ECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
Query: 538 VLGRERQCV--PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
+ CV CN P G DG C+C + G CD + D + C
Sbjct: 1394 HCDQACSCVHGRCNQGPLG--------DGSCDCDVGWRGVHCDNATT-----EDNCNGTC 1440
Query: 596 DVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC-GS 654
S + + D C C + F G C ACE N G ++ A C +
Sbjct: 1441 HTSANCLTNSDGTASCKCAAGFQG-NGTICTA----INACEISN----GGCSAKADCKRT 1491
Query: 655 VPAGELCQCKDRV--QGRICNDCKPLYWN------LQEYNPFGCEQ--CNCNLAGT---- 700
P +C CK G +C + P N E G Q CNC A T
Sbjct: 1492 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGK 1551
Query: 701 -LNSLGACNTKSGQC----VCKQHVG--ERQC 725
+ C TK+G C +C H G ER C
Sbjct: 1552 VCTLINVCLTKNGGCSEFAIC-NHTGQVERTC 1582
Score = 63.7 bits (148), Expect = 1e-08
Identities = 60/195 (30%), Positives = 76/195 (38%), Gaps = 42/195 (21%)
Query: 1913 CAPGFYGDAIFSKNCTACI------CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDH 1965
C G++G ++C AC C+ G+ D S TG C C G G C+ C P
Sbjct: 1950 CCKGYFG-----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 1966 WGLNTGLGCTPCNCGIASESTQCDDD---NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+G + C PC C S+ QCDD +GQC C G TG CD A T
Sbjct: 2005 FGPD----CLPCGC---SDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSA 2057
Query: 2023 H--------CNCNTGY-SVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP---QEG--- 2067
H C CN Y G C C+ G K RC ++ + Q+G
Sbjct: 2058 HATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCA-KVARCSQKGTKVSCSCQKGYKG 2116
Query: 2068 ----CLECDSCTDAL 2078
C E D C D L
Sbjct: 2117 DGHSCTEIDPCADGL 2131
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/321 (26%), Positives = 115/321 (35%), Gaps = 55/321 (17%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDE-LDVCQPCQCDPHFSTGNCEEESGRCE 380
GG+C C C T P RW + V Q C + F E R
Sbjct: 1887 GGRCDTFTTFDASGECGSCVNT---PSCPRWSKPKGVKQKCLYNLPFKRNL---EGCRER 1940
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCT------CNLNGTEGEHCTPTDGLCPCKYNYAGK 434
C Q P C GYF +C+ C CN G + + T G C C + G
Sbjct: 1941 CSLVIQIPRCCK---GYFGR-DCQACPGGPDAPCNNRGVCLDQYSAT-GECKCNTGFNGT 1995
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLT--GDCTCKSKYSGRTCNQ-------CQ 485
+CE+C G + P+C C C+ G D +T G C C++ ++G +C+ C
Sbjct: 1996 ACEMCWPGRFGPDCLPCGCSDHGQCD---DGITGSGQCLCETGWTGPSCDTQAVLPAVCT 2052
Query: 486 AGYYNYPTCK-----PCNCDTSG-----TEPSICDDVSGQC--ICKAGFGGPRCD-QCLS 532
+ TCK CN D G T C +G C + + G + C
Sbjct: 2053 PPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQK 2112
Query: 533 GYYMQVLGRERQCVPCNCDP-TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
GY G C DP + C C +T G +C +C Y D L
Sbjct: 2113 GY----KGDGHSCT--EIDPCADGLNGGCHEHATCK-MTGPGKHKC-ECKSHY--VGDGL 2162
Query: 592 SCNCDVSGSIGSTCDDNGLCH 612
+C + I DNG CH
Sbjct: 2163 NCEPE-QLPIDRCLQDNGQCH 2182
Score = 60.9 bits (141), Expect = 8e-08
Identities = 61/235 (25%), Positives = 90/235 (38%), Gaps = 41/235 (17%)
Query: 439 CEDGYYSPECKNCECNT--VGSVSYVC-DKL--TGDCTCKSKYSGRTCNQCQAGYYNYPT 493
C G++ P+C+ C N V + +C D + TG C C +SG C C G Y
Sbjct: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395
Query: 494 CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
+ C+C D G C C G+ G CD + NC+ T
Sbjct: 1396 DQACSCVHGRCNQGPLGD--GSCDCDVGWRGVHCDNATT--------------EDNCNGT 1439
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN-CDVS-GSIGSTCD---- 606
TS NCLTN G +C+ G+ C + N C++S G + D
Sbjct: 1440 CHTS--------ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT 1491
Query: 607 --DNGLCHCKSNF--DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPA 657
+C CK+ + DG C N+ C++ N + + A C +PA
Sbjct: 1492 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDK-NAECTQTGPNQAACNCLPA 1545
Score = 59.3 bits (137), Expect = 3e-07
Identities = 64/259 (24%), Positives = 89/259 (34%), Gaps = 35/259 (13%)
Query: 381 CRPEFQPPDCSSCAYG--YFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEI 438
CR ++ P C +G + P CN G+ E +G C C+ + G +CE
Sbjct: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEG-NGTCSCQEGFGGTACET 149
Query: 439 C-EDGYYSPECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPC 497
C +D + P C + CN V V G C C S Y+G C++ P C
Sbjct: 150 CADDNLFGPSCSSV-CNCVHGVCNSGLDGDGTCECYSAYTGPKCDK------PIPECAAL 202
Query: 498 NC-DTSGTEPSICDDVSGQCICKAGF--GGPRCDQ--------CLSGYYMQVLGRERQCV 546
C + S PS D+ +C C + G CD C + LG R
Sbjct: 203 LCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSC 262
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC---------DV 597
C G D C NFG + + Y P C C V
Sbjct: 263 TCQEGYRGDGQVCLPVD---PCQINFGNCP-TKSTVCKYDGPGQSHCECKEHYQNFVPGV 318
Query: 598 SGSIGSTCDDNGLCHCKSN 616
S+ C + CH +N
Sbjct: 319 GCSMTDICKSDNPCHRNAN 337
Score = 56.0 bits (129), Expect = 2e-06
Identities = 56/214 (26%), Positives = 80/214 (37%), Gaps = 24/214 (11%)
Query: 1872 DYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACI 1931
++C P +G D S +I +C C N G C ++ ++C
Sbjct: 17 NFCSPAETTGQARRCDRKSLLTIRTECRSCALNL-GVKCPDGYTMITSGSVGVRDCRYT- 74
Query: 1932 CDEFGMADCDSTTGTC--VCRPGVIGEKCDRCAPDHWGLNT----GLGCTPCNC-GIASE 1984
F + + C +CR + RC P WG + G +PCN G +E
Sbjct: 75 ---FEVRTYSLSLPGCRHICRKDYLQP---RCCPGRWGPDCIECPGGAGSPCNGRGSCAE 128
Query: 1985 STQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDH-CNCNTGYSVGFMCNATGQCE 2043
+ NG C C +G G C+ CA N C CNC G + + G CE
Sbjct: 129 GME---GNGTCSCQEGFGGTACETCADD--NLFGPSCSSVCNCVHGVCNSGL-DGDGTCE 182
Query: 2044 CLPGVIGEKCDR-CPERWVLIPQEGCLECDSCTD 2076
C G KCD+ PE L+ E C T+
Sbjct: 183 CYSAYTGPKCDKPIPECAALLCPENS-RCSPSTE 215
Score = 55.2 bits (127), Expect = 4e-06
Identities = 72/281 (25%), Positives = 100/281 (35%), Gaps = 35/281 (12%)
Query: 393 CAYGYFDYPNCKPC------TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
C G+F P C+PC C NG + T G+C C ++G +CE C +G Y
Sbjct: 1336 CCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGT-GVCECGEGFSGTACETCTEGKYGI 1393
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC-KPCNCDTSGTE 505
C C+ V G C C + G C+ TC NC T+
Sbjct: 1394 HCDQA-CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN--- 1449
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL-GRERQCVPCNCDPTGSTSTSCSA-- 562
D + C C AGF G C + ++ G C G +C A
Sbjct: 1450 ----SDGTASCKCAAGFQG-NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY 1504
Query: 563 --DG----KCN-CLTNFGGAQCDQCSPGYYKYPDCLSCNC-DVSGSIGSTCDDNGLCHCK 614
DG + N CL N GG CD+ + P+ +CNC G C +C K
Sbjct: 1505 TGDGIVCLEINPCLENHGG--CDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK 1562
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSV 655
N ++ C + C C P + F GS+
Sbjct: 1563 -NGGCSEFAICN---HTGQVERTCTCKPNYIGDGFTCRGSI 1599
Score = 55.2 bits (127), Expect = 4e-06
Identities = 67/246 (27%), Positives = 91/246 (36%), Gaps = 49/246 (19%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C GY G RDC C P NN + D + + C C G+ G CE C
Sbjct: 1950 CCKGYFG-------RDCQACPGGPDAPCNNRGVCLD--QYSATGECKCNTGFNGTACEMC 2000
Query: 1856 AAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD---SINGDCLKCVNNTAGAACN- 1911
G +G P+ C PC CS D G CD + +G CL C G +C+
Sbjct: 2001 WPGRFG-PD---------CLPCGCS------DHGQCDDGITGSGQCL-CETGWTGPSCDT 2043
Query: 1912 ------LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG-EKCDRCAPD 1964
+C P A +N T C C+ D + T C+ G K RC+
Sbjct: 2044 QAVLPAVCTPPCSAHATCKENNT-CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
T + C+ C G + C + + CA G+ G C + A T G C
Sbjct: 2103 ----GTKVSCS-CQKGYKGDGHSCTEID---PCADGLNG-GCHEHAT--CKMTGPGKHKC 2151
Query: 2025 NCNTGY 2030
C + Y
Sbjct: 2152 ECKSHY 2157
Score = 55.2 bits (127), Expect = 4e-06
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 38/190 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD----NGMCICPKNVEGENCD 1412
G+C C G C C G +G P+C PC C CDD +G C+C G +CD
Sbjct: 1984 GECKCNTGFNGTACEMCWPGRFG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD 2042
Query: 1413 R-------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ------CEADSGKCA--CRENV 1457
C P + + C CN L G+ + C+ D+G CA R +
Sbjct: 2043 TQAVLPAVCTPPCSAHATCKENNTCECN-LDYEGDGITCTVVDFCKQDNGGCAKVARCSQ 2101
Query: 1458 RG-RVCDHCVPGHYAFPDCYQCT------------CNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G +V C G+ D + CT C+ H T + +C CK++
Sbjct: 2102 KGTKVSCSCQKGYKG--DGHSCTEIDPCADGLNGGCHEHATC-KMTGPGKHKCECKSHYV 2158
Query: 1505 GQACDTCKEE 1514
G + C+ E
Sbjct: 2159 GDGLN-CEPE 2167
Score = 53.6 bits (123), Expect = 1e-05
Identities = 68/263 (25%), Positives = 97/263 (36%), Gaps = 39/263 (14%)
Query: 518 CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQC 577
C GF GP C+QC G+ C G + S +G C C F G+QC
Sbjct: 728 CCKGFYGPDCNQCPGGFSNP------------CSGNGQCADSLGGNGTCICEEGFQGSQC 775
Query: 578 DQCSPGYYKYPDC-LSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNY-PAC 635
CS P C C C V G+ + D +G C + DG+ C +Q P
Sbjct: 776 QFCSDPNKYGPRCNKKCLC-VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV 834
Query: 636 EECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQ-CN 694
+ C+ T ++ G+ A +C+ G +C++ P P GC +
Sbjct: 835 QFCHIH---ATCEYSN-GT--ASCICKAGYEGDGTLCSEMDP----CTGLTPGGCSRNAE 884
Query: 695 CNLAGTLNSLGACN---TKSGQ-CVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCD- 749
C GT C T +G+ C + C D L G EC+C
Sbjct: 885 CIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP--GQNECECKK 942
Query: 750 --IGGSID----NNCDKTTGQCH 766
G ID +C + TG+CH
Sbjct: 943 GFRGNGIDCEPITSCLEQTGKCH 965
Score = 52.0 bits (119), Expect = 4e-05
Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 17/140 (12%)
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCD------QCSPGYYKYPDCLSCN------ 594
P N +PT + C G+ L + C+ +C G+Y PDC C
Sbjct: 689 PANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYG-PDCNQCPGGFSNP 747
Query: 595 CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPAC-EECNCDPRGVTASFAGCG 653
C +G + NG C C+ F G++C C + P C ++C C G
Sbjct: 748 CSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDG 807
Query: 654 SVPAGELCQCKDRVQGRICN 673
+ G C+D GR+C+
Sbjct: 808 ACLTG---TCRDGSAGRLCD 824
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/203 (24%), Positives = 65/203 (32%), Gaps = 21/203 (10%)
Query: 1852 CEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCL--KCVNNTAGAA 1909
C C+ Y+ T + C SG G N KC G
Sbjct: 677 CVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPD 736
Query: 1910 CNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCA-PDHWGL 1968
CN C GF + C AD GTC+C G G +C C+ P+ +G
Sbjct: 737 CNQCPGGFSNPCSGNGQC----------ADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP 786
Query: 1969 NTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNT 2028
C C G + D C G G+ CD+ + Y + H C
Sbjct: 787 RCNKKCL-CVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCE- 844
Query: 2029 GYSVGFMCNATGQCECLPGVIGE 2051
YS N T C C G G+
Sbjct: 845 -YS-----NGTASCICKAGYEGD 861
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 31/180 (17%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
C GY+G +C+ C A C++ G+C+ C G C+ C P F D
Sbjct: 1950 CCKGYFG-RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNR 1482
C C C+ G + + SG+C C G CD P C+
Sbjct: 2009 ----CLPCGCSDHGQCDDGI---TGSGQCLCETGWTGPSCD----TQAVLPAVCTPPCSA 2057
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK-CFCFGKTTRCSSS 1541
H T C +N C C + G TC F QD+ GC K C K T+ S S
Sbjct: 2058 HAT----CKENNT-CECNLDYEGDGI-TCTVVDFCKQDNG--GCAKVARCSQKGTKVSCS 2109
Score = 50.8 bits (116), Expect = 9e-05
Identities = 72/285 (25%), Positives = 99/285 (34%), Gaps = 41/285 (14%)
Query: 358 CQPCQCDPH---FSTGNCEEE---SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLN 411
CQPC + F G C + +G CEC F C +C G + + C+C ++
Sbjct: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 1403
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + DG C C + G C D + + N C+T + D T C
Sbjct: 1404 GRCNQG-PLGDGSCDCDVGWRGVHC----DNATTEDNCNGTCHTSANCLTNSDG-TASCK 1457
Query: 472 CKSKY--SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ 529
C + + +G C A + C D T P C CKAG+ G
Sbjct: 1458 CAAGFQGNGTICTAINACEISNGGCS-AKADCKRTTPG-----RRVCTCKAGYTGDGI-V 1510
Query: 530 CLSGYYMQVLGRERQC-VPCNCDPTGSTSTSCSADGKCNCLTNF--GGAQCDQCSPGYYK 586
CL L C C TG + CNCL + G C + K
Sbjct: 1511 CLE--INPCLENHGGCDKNAECTQTGPNQAA------CNCLPAYTGDGKVCTLINVCLTK 1562
Query: 587 YPDCLS-CNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY 630
C C+ +G + TC CK N+ G TCR Y
Sbjct: 1563 NGGCSEFAICNHTGQVERTCT------CKPNYIGDGF-TCRGSIY 1600
Score = 50.4 bits (115), Expect = 1e-04
Identities = 69/314 (21%), Positives = 102/314 (32%), Gaps = 47/314 (14%)
Query: 1737 QCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFC 1796
+C + + G C QC P GF PC NG G C+ C + G C+FC
Sbjct: 727 KCCKGFYGPDCNQC-------PGGFSNPCSGNGQCADSLGGNGTCI-CEEGFQGSQCQFC 778
Query: 1797 MSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC- 1855
C+ C S+ L+ + + C+ Q G ++C
Sbjct: 779 SDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCH 838
Query: 1856 --AAGYYGIPEDTDLHTGDYCKPCNCSGNINP---QDPGSCDSINGDCLKCVNNTAGAAC 1910
A Y + + Y ++P PG C S N +C+K T C
Sbjct: 839 IHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC-SRNAECIK--TGTGTHTC 895
Query: 1911 NLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNT 1970
+C G+ G+ C+ G C PG +C+ C G
Sbjct: 896 -VCQQGWTGNGRDCSEINNCLLPSAG--GCHDNASCLYVGPG--QNECE-CKKGFRG--N 947
Query: 1971 GLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGY 2030
G+ C P T C + G+C C ++G W+ C C GY
Sbjct: 948 GIDCEPI--------TSCLEQTGKCHPL-----ASCQSTSSGVWS--------CVCQEGY 986
Query: 2031 -SVGFMCNATGQCE 2043
GF+C E
Sbjct: 987 EGDGFLCYGNAAVE 1000
Score = 48.4 bits (110), Expect = 5e-04
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 36/192 (18%)
Query: 1320 GLCREAMFSITSEYNSGA-----RPCLCD--FMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
G CR +T + + + R C+ FMG L G Q C VI R C A
Sbjct: 1282 GRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTL---FIGCQPKCVRTVITRECCA 1338
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
G++G P C+PC + +C NG+C+ C + G C+ C +
Sbjct: 1339 ---GFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
Query: 1423 VQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY---QC 1478
CD C+C V G Q G C C RG CD+ C+ C
Sbjct: 1395 ----CDQACSC----VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC 1446
Query: 1479 TCNRHGTTYDVC 1490
N GT C
Sbjct: 1447 LTNSDGTASCKC 1458
Score = 48.0 bits (109), Expect = 6e-04
Identities = 46/167 (27%), Positives = 59/167 (35%), Gaps = 24/167 (14%)
Query: 1373 CRTGYYGFPNCRPCH------CPSTAICDD----NGMCICPKNVEGENCDRCK-PYTFNF 1421
C G+YG P+C C C C D NG CIC + +G C C P +
Sbjct: 728 CCKGFYG-PDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG- 785
Query: 1422 DVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCN 1481
R C C G N++ + CR+ GR+CD P Y C+
Sbjct: 786 --PRCNKKCLC-VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--CGP--YVQFCH 838
Query: 1482 RHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK 1528
H T TA C CK G T E P GC++
Sbjct: 839 IHATC--EYSNGTASCICKAGYEGDG--TLCSEMDPCTGLTPGGCSR 881
Score = 47.2 bits (107), Expect = 0.001
Identities = 58/219 (26%), Positives = 77/219 (35%), Gaps = 31/219 (14%)
Query: 568 CLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCRE 627
C F G QC C PG + C + G G+ G+C C F G C+TC E
Sbjct: 1336 CCAGFFGPQCQPC-PGNAQNV-CFGNGICLDGVNGT-----GVCECGEGFSGTACETCTE 1388
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAG---ELCQCKDRVQGRICNDCKPLYWNLQE 684
Y + C+C G GS C + CN N
Sbjct: 1389 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLT 1448
Query: 685 YNPFGCEQCNCNLA----GTL-NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRL 735
N G C C GT+ ++ AC +G C CK+ R+ C G+
Sbjct: 1449 -NSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--- 1504
Query: 736 QTNDVFGCTECD-C-DIGGSIDNNCDKT-TG----QCHC 767
T D C E + C + G D N + T TG C+C
Sbjct: 1505 -TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC 1542
Score = 46.8 bits (106), Expect = 0.001
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 33/140 (23%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD---VNTGICLNCADNTIGD 1791
EC+C + G +CE C G + P C+PC C+ H QCD +G CL C G
Sbjct: 1985 ECKCNTGFNGTACEMCWPGRFG-PD--CLPCGCSDHG-QCDDGITGSGQCL-CETGWTGP 2039
Query: 1792 HCE-------FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS----CD--------- 1831
C+ C AT ++ C C + Y + + C
Sbjct: 2040 SCDTQAVLPAVCTPPCSAHATC---KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKV 2096
Query: 1832 --LSENGSLISCNCQPGYGG 1849
S+ G+ +SC+CQ GY G
Sbjct: 2097 ARCSQKGTKVSCSCQKGYKG 2116
Score = 46.4 bits (105), Expect = 0.002
Identities = 78/303 (25%), Positives = 108/303 (35%), Gaps = 47/303 (15%)
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICE 440
C + P C YG P+C C G P G C + G ICE
Sbjct: 719 CNATVKIPKCCKGFYG----PDCNQCP-------GGFSNPCSGNGQCADSLGGNGTCICE 767
Query: 441 DGYYSPECKNC-ECNTVG-SVSYVCDKLTGDCTCKSKYSGR----TCNQCQAGYYNYPTC 494
+G+ +C+ C + N G + C + G C + G TC AG
Sbjct: 768 EGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQT 827
Query: 495 KPCNCDTSGTE-PSICDDVSG--QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCD 551
C + C+ +G CICKAG+ G D L + PC
Sbjct: 828 SACGPYVQFCHIHATCEYSNGTASCICKAGYEG---DGTLCS----------EMDPC--- 871
Query: 552 PTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCNCDVSGSIGSTCDDNGL 610
TG T CS + +C T G C C G+ DC N + S G C DN
Sbjct: 872 -TGLTPGGCSRNAEC-IKTGTGTHTC-VCQQGWTGNGRDCSEINNCLLPSAGG-CHDNAS 927
Query: 611 CHCKSNFDGAKCDTCREQFY-NYPACEE-CNC-DPRGVTASFAGCGSVPAGE-LCQCKDR 666
C +C+ C++ F N CE +C + G A C S +G C C++
Sbjct: 928 CLYVGPGQN-ECE-CKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEG 985
Query: 667 VQG 669
+G
Sbjct: 986 YEG 988
Score = 45.2 bits (102), Expect = 0.005
Identities = 46/184 (25%), Positives = 64/184 (34%), Gaps = 27/184 (14%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRP-CHCPSTAIC----DDNGMCICPKNVEGENC 1411
G C C+ G C C P+C C+C +C D +G C C G C
Sbjct: 134 GTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH-GVCNSGLDGDGTCECYSAYTGPKC 192
Query: 1412 DRCKPYTFNFDVQRGCDDCNCNPLGVVGNQLQCE------ADSGKCACRENVRGRVCDHC 1465
D+ P ++ C+P N+L+C+ D C ++C
Sbjct: 193 DKPIPECAALLCP---ENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPH 249
Query: 1466 VPGHYAFPDCYQCTCNR--HG-----TTYDVCDQNTAQC-----YCKTNVRGQACDTCKE 1513
Y P+ + CTC G D C N C CK + GQ+ CKE
Sbjct: 250 AHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKE 309
Query: 1514 EYFN 1517
Y N
Sbjct: 310 HYQN 313
Score = 44.0 bits (99), Expect = 0.010
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 15/97 (15%)
Query: 690 CEQCNCNLAGTLNSLGACNTK---SGQCVCKQHVGERQCDQCLDGFYRLQTNDVFG--CT 744
C +C N G+C +G C C++ G C+ C D +++FG C+
Sbjct: 109 CIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCAD-------DNLFGPSCS 161
Query: 745 E-CDCDIGGSIDNNCDKTTGQCHCHSRVEGRRCDQPI 780
C+C + G ++ D G C C+S G +CD+PI
Sbjct: 162 SVCNC-VHGVCNSGLDGD-GTCECYSAYTGPKCDKPI 196
Score = 43.6 bits (98), Expect = 0.014
Identities = 66/257 (25%), Positives = 86/257 (33%), Gaps = 61/257 (23%)
Query: 1811 DCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDTDLHT 1870
DC+ C P N SC G+ +C+CQ G+GG CE CA D +L
Sbjct: 108 DCIECPGGAGSPCNGRG-SCAEGMEGNG-TCSCQEGFGGTACETCA--------DDNLFG 157
Query: 1871 GDYCKPCNCSGNINPQDPGSCDS-INGD-CLKCVNNTAGAACNLCAPGFYGDAIFSKNCT 1928
CNC G C+S ++GD +C + G C+ P C
Sbjct: 158 PSCSSVCNCV-------HGVCNSGLDGDGTCECYSAYTGPKCDKPIP----------ECA 200
Query: 1929 ACICDEFGMADC---DSTTGTCVCRPGVIGE--KCDRCAPDHWGLNTGLGCTPCNCGIAS 1983
A +C E D C C P G+ CD P C C +
Sbjct: 201 ALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP----------CLRKICHPHA 250
Query: 1984 ESTQCDDDNGQCRCAKGV--TGKQC---DQCAAGFWN---------YTKDGCDHCNCNTG 2029
T + C C +G G+ C D C F N Y G HC C
Sbjct: 251 HCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH 310
Query: 2030 YS---VGFMCNATGQCE 2043
Y G C+ T C+
Sbjct: 311 YQNFVPGVGCSMTDICK 327
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/225 (26%), Positives = 81/225 (36%), Gaps = 38/225 (16%)
Query: 576 QCDQCSPGYYKYPDCLSCN------CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
Q +C GY+ DC +C C+ G G C C + F+G C+ C
Sbjct: 1946 QIPRCCKGYFGR-DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 2004
Query: 630 YNYPACEECNCDPR-----GVTAS-FAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ P C C C G+T S C + G C + V +C + +
Sbjct: 2005 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQ-AVLPAVCTPPCSAHATCK 2062
Query: 684 EYNPFGCEQCNCNLAG---TLNSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ 736
E N CE CN + G T + C +G C C Q + C C G+
Sbjct: 2063 ENNT--CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC-SCQKGY---- 2114
Query: 737 TNDVFGCTECD-CD---IGGSIDNNCDKTTG----QCHCHSRVEG 773
D CTE D C GG ++ K TG +C C S G
Sbjct: 2115 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 2159
Score = 41.5 bits (93), Expect = 0.056
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
CD F D G+CV P C R + L P + +C
Sbjct: 1890 CDTFTTFDASGECGSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLV 1944
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGE 2051
RC KG G+ C C G D CN N G + +ATG+C+C G G
Sbjct: 1945 IQIPRCCKGYFGRDCQACPGG-----PDA--PCN-NRGVCLD-QYSATGECKCNTGFNGT 1995
Query: 2052 KCDRCPERWVLIPQEGCLECDSCTD 2076
C+ C W CL C C+D
Sbjct: 1996 ACEMC---WPGRFGPDCLPC-GCSD 2016
Score = 39.5 bits (88), Expect = 0.22
Identities = 38/146 (26%), Positives = 49/146 (33%), Gaps = 13/146 (8%)
Query: 340 CRPTYYRPY---GKRWDELDVCQPCQCDPHFSTGNCEEE---SGRCECRPEFQPPDCSSC 393
CR Y +P G+ + C P G+C E +G C C+ F C +C
Sbjct: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
Query: 394 AYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCEC 453
A P+C CN DG C C Y G C+ PEC C
Sbjct: 151 ADDNLFGPSCS-SVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD-----KPIPECAALLC 204
Query: 454 NTVGSVS-YVCDKLTGDCTCKSKYSG 478
S D+ +C C Y G
Sbjct: 205 PENSRCSPSTEDENKLECKCLPNYRG 230
Score = 39.5 bits (88), Expect = 0.22
Identities = 62/247 (25%), Positives = 88/247 (35%), Gaps = 47/247 (19%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLP----SGFCVPCQCNGHSDQCDVNTGICL--NCADNTI 1789
C C ++G C+ C++ + P CV CN D + G CL C D +
Sbjct: 764 CICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRID----SDGACLTGTCRDGSA 819
Query: 1790 GDHCEFCMSG-------YHGDATVGTPRDCLICACPMPYPSNNFALS----C-DLSENGS 1837
G C+ S H AT C C Y + S C L+ G
Sbjct: 820 GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC 879
Query: 1838 LISCNC-QPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSING 1896
+ C + G G C C G+ G D C+ N G C N
Sbjct: 880 SRNAECIKTGTGTHTC-VCQQGWTGNGRD-----------CSEINNCLLPSAGGCHD-NA 926
Query: 1897 DCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG----MADCDSTTG---TCVC 1949
CL C C GF G+ I + T+C+ ++ G +A C ST+ +CVC
Sbjct: 927 SCLYV--GPGQNECE-CKKGFRGNGIDCEPITSCL-EQTGKCHPLASCQSTSSGVWSCVC 982
Query: 1950 RPGVIGE 1956
+ G G+
Sbjct: 983 QEGYEGD 989
Score = 38.7 bits (86), Expect = 0.39
Identities = 41/152 (26%), Positives = 51/152 (33%), Gaps = 18/152 (11%)
Query: 1361 CKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFN 1420
C P G C C G G P C + NG C C + G C+ C N
Sbjct: 100 CCPGRWGPDCIECPGGA-GSPCNGRGSCAEGM--EGNGTCSCQEGFGGTACETCA--DDN 154
Query: 1421 FDVQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTC 1480
CNC GV + L G C C G CD + P+C C
Sbjct: 155 LFGPSCSSVCNC-VHGVCNSGLD---GDGTCECYSAYTGPKCDKPI------PECAALLC 204
Query: 1481 NRHG-TTYDVCDQNTAQCYCKTNVRGQA--CD 1509
+ + D+N +C C N RG CD
Sbjct: 205 PENSRCSPSTEDENKLECKCLPNYRGDGKYCD 236
Score = 38.7 bits (86), Expect = 0.39
Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 11/94 (11%)
Query: 1427 CDDCNCNPLGVV-GNQLQCEA--DSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRH 1483
C C N V GN + + +G C C E G C+ C G Y C+C H
Sbjct: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 1403
Query: 1484 GTTYDVCDQ---NTAQCYCKTNVRGQACDTCKEE 1514
G C+Q C C RG CD E
Sbjct: 1404 GR----CNQGPLGDGSCDCDVGWRGVHCDNATTE 1433
Score = 37.9 bits (84), Expect = 0.68
Identities = 34/120 (28%), Positives = 47/120 (39%), Gaps = 20/120 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C C + G +CE CA+ + PS C S C+ G+C + D GD
Sbjct: 136 CSCQEGFGGTACETCADDNLFGPS--C--------SSVCNCVHGVCNSGLD---GDGTCE 182
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C S Y G +C CP N S +E+ + + C C P Y G +YC
Sbjct: 183 CYSAYTGPKCDKPIPECAALLCP-----ENSRCS-PSTEDENKLECKCLPNYRGDG-KYC 235
Score = 36.7 bits (81), Expect = 1.6
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 8/56 (14%)
Query: 1465 CVPGHYAFPDCYQCT------CNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEE 1514
C PG + PDC +C CN G+ + + N C C+ G AC+TC ++
Sbjct: 100 CCPGRWG-PDCIECPGGAGSPCNGRGSCAEGMEGN-GTCSCQEGFGGTACETCADD 153
Score = 35.9 bits (79), Expect = 2.8
Identities = 65/274 (23%), Positives = 90/274 (32%), Gaps = 40/274 (14%)
Query: 248 NLNILVCRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCE-PCNCHN--HTTEC---- 300
N + + +C GP CN+C GF Q D C C ++C
Sbjct: 720 NATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCS 779
Query: 301 ---TYDPEIDEKRLSL--DINGRYEGGGKCL--NCQHNTEGINCNKCRPTYYRPYGKRWD 353
Y P ++K L + N R + G CL C+ + G C+K + + PY +
Sbjct: 780 DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDK-QTSACGPYVQFCH 838
Query: 354 ELDVCQ------PCQCDPHF-STGNCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPC 406
C+ C C + G E C P CS A C
Sbjct: 839 IHATCEYSNGTASCICKAGYEGDGTLCSEMDPC---TGLTPGGCSRNAECIKTGTGTHTC 895
Query: 407 TCNLNGT-EGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCEC------NTVGSV 459
C T G C+ + C AG + Y P CEC N +
Sbjct: 896 VCQQGWTGNGRDCSEINN---CLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCE 952
Query: 460 SYV-CDKLTGDC----TCKSKYSGRTCNQCQAGY 488
C + TG C +C+S SG CQ GY
Sbjct: 953 PITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
Score = 35.1 bits (77), Expect = 4.8
Identities = 21/80 (26%), Positives = 28/80 (35%), Gaps = 6/80 (7%)
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD--VC---DQNTAQCYCKTNVRGQACDTC 1511
VR + C G + P C C N + +C T C C G AC+TC
Sbjct: 1328 VRTVITRECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETC 1386
Query: 1512 KEEYFNLQDDNPDGCTKCFC 1531
E + + D C C
Sbjct: 1387 TEGKYGIHCDQACSCVHGRC 1406
Score = 34.3 bits (75), Expect = 8.4
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 9/63 (14%)
Query: 1996 RCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEKCDR 2055
+C KG G C+QC GF N G C + G G C C G G +C
Sbjct: 727 KCCKGFYGPDCNQCPGGFSN-PCSGNGQCADSLG--------GNGTCICEEGFQGSQCQF 777
Query: 2056 CPE 2058
C +
Sbjct: 778 CSD 780
>AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for
endocytosis precursor protein.
Length = 1416
Score = 74.5 bits (175), Expect = 6e-12
Identities = 65/240 (27%), Positives = 94/240 (39%), Gaps = 39/240 (16%)
Query: 1736 CQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEF 1795
C+C + G +CE C EG Y + C +G +Q + G C +C G HC+
Sbjct: 237 CECGEGFSGTACETCTEGKYGIHCDQACSC-VHGRCNQGPLGDGSC-DCDVGWRGVHCDN 294
Query: 1796 CMSGYHGDATVGTPRDCLI-------CACPMPYPSNNFAL----SCDLSENGSLISCNCQ 1844
+ + + T T +CL C C + N +C++S G +C+
Sbjct: 295 ATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 354
Query: 1845 PGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINP--QDPGSCDSINGDCLKCV 1902
G R C AGY G G C INP ++ G CD N +C +
Sbjct: 355 RTTPGRRVCTCKAGYTG--------DGIVCL------EINPCLENHGGCDK-NAECTQTG 399
Query: 1903 NNTAGAACNLCAPGFYGDAIFSKNCTACI-----CDEFGMAD-CDSTTGTCVCRPGVIGE 1956
N AACN C P + GD C+ C EF + + TC C+P IG+
Sbjct: 400 PNQ--AACN-CLPAYTGDGKVCTLIYVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGD 456
Score = 69.7 bits (163), Expect = 2e-10
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 529 QCLSGYYMQVLGRERQCVP----CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGY 584
+C GY+ GR+ Q P C+ G SA G+C C T F G C+ C PG
Sbjct: 814 RCCKGYF----GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 869
Query: 585 YKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT 624
+ PDCL C C G +G C C++ + G CDT
Sbjct: 870 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 908
Score = 67.3 bits (157), Expect = 1e-09
Identities = 70/246 (28%), Positives = 95/246 (38%), Gaps = 50/246 (20%)
Query: 1835 NGSLISCNCQPGYGGARCEYCAAGYYGIPED---TDLHTGDYCKP-----CNCS---GNI 1883
NG+ + C C G+ G CE C G YGI D + +H P C+C +
Sbjct: 232 NGTGV-CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGV 290
Query: 1884 NPQDPGSCDSINGDC---LKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFG---M 1937
+ + + D+ NG C C+ N+ G A CA GF G+ AC G
Sbjct: 291 HCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAK 350
Query: 1938 ADCDSTT---GTCVCRPGVIGE-----KCDRCAPDHWGLNTGLGCTPCNCGIASESTQCD 1989
ADC TT C C+ G G+ + + C +H G C +E TQ
Sbjct: 351 ADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGG-----------CDKNAECTQTG 399
Query: 1990 DDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQ----CECL 2045
+ C C TG C + TK+G G S +CN TGQ C C
Sbjct: 400 PNQAACNCLPAYTG-DGKVCTLIYVCLTKNG--------GCSEFAICNHTGQVERTCTCK 450
Query: 2046 PGVIGE 2051
P IG+
Sbjct: 451 PNYIGD 456
Score = 65.3 bits (152), Expect = 4e-09
Identities = 37/99 (37%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 1414 CKPYTFNFDVQR--GCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYA 1471
CK Y F D Q G D CN GV +Q +G+C C G C+ C PG +
Sbjct: 816 CKGY-FGRDCQACPGGPDAPCNNRGVCLDQYSA---TGECKCNTGFNGTACEMCWPGRFG 871
Query: 1472 FPDCYQCTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDT 1510
PDC C C+ HG D + QC C+T G +CDT
Sbjct: 872 -PDCLPCGCSDHGQCDDGI-TGSGQCLCETGWTGPSCDT 908
Score = 63.7 bits (148), Expect = 1e-08
Identities = 66/236 (27%), Positives = 91/236 (38%), Gaps = 39/236 (16%)
Query: 483 QCQAGYYNYPTCKPC--NCDTSGTEPSIC-DDVSGQ--CICKAGFGGPRCDQCLSGYYMQ 537
+C AG++ P C+PC N IC D V+G C C GF G C+ C G Y
Sbjct: 200 ECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 258
Query: 538 VLGRERQCV--PCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNC 595
+ CV CN P G DG C+C + G CD + D + C
Sbjct: 259 HCDQACSCVHGRCNQGPLG--------DGSCDCDVGWRGVHCDNATT-----EDNCNGTC 305
Query: 596 DVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGC-GS 654
S + + D C C + F G C ACE N G ++ A C +
Sbjct: 306 HTSANCLTNSDGTASCKCAAGFQG-NGTICTA----INACEISN----GGCSAKADCKRT 356
Query: 655 VPAGELCQCKDRV--QGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACN 708
P +C CK G +C + P L+ + GC++ N T + ACN
Sbjct: 357 TPGRRVCTCKAGYTGDGIVCLEINPC---LENHG--GCDK-NAECTQTGPNQAACN 406
Score = 63.7 bits (148), Expect = 1e-08
Identities = 60/195 (30%), Positives = 76/195 (38%), Gaps = 42/195 (21%)
Query: 1913 CAPGFYGDAIFSKNCTACI------CDEFGMA-DCDSTTGTCVCRPGVIGEKCDRCAPDH 1965
C G++G ++C AC C+ G+ D S TG C C G G C+ C P
Sbjct: 815 CCKGYFG-----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 869
Query: 1966 WGLNTGLGCTPCNCGIASESTQCDDD---NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCD 2022
+G + C PC C S+ QCDD +GQC C G TG CD A T
Sbjct: 870 FGPD----CLPCGC---SDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSA 922
Query: 2023 H--------CNCNTGY-SVGFMCNATGQCECLPGVIGEKCDRCPERWVLIP---QEG--- 2067
H C CN Y G C C+ G K RC ++ + Q+G
Sbjct: 923 HATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCA-KVARCSQKGTKVSCSCQKGYKG 981
Query: 2068 ----CLECDSCTDAL 2078
C E D C D L
Sbjct: 982 DGHSCTEIDPCADGL 996
Score = 61.7 bits (143), Expect = 5e-08
Identities = 84/321 (26%), Positives = 115/321 (35%), Gaps = 55/321 (17%)
Query: 322 GGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDE-LDVCQPCQCDPHFSTGNCEEESGRCE 380
GG+C C C T P RW + V Q C + F E R
Sbjct: 752 GGRCDTFTTFDASGECGSCVNT---PSCPRWSKPKGVKQKCLYNLPFKRNL---EGCRER 805
Query: 381 CRPEFQPPDCSSCAYGYFDYPNCKPCT------CNLNGTEGEHCTPTDGLCPCKYNYAGK 434
C Q P C GYF +C+ C CN G + + T G C C + G
Sbjct: 806 CSLVIQIPRCCK---GYFGR-DCQACPGGPDAPCNNRGVCLDQYSAT-GECKCNTGFNGT 860
Query: 435 SCEICEDGYYSPECKNCECNTVGSVSYVCDKLT--GDCTCKSKYSGRTCNQ-------CQ 485
+CE+C G + P+C C C+ G D +T G C C++ ++G +C+ C
Sbjct: 861 ACEMCWPGRFGPDCLPCGCSDHGQCD---DGITGSGQCLCETGWTGPSCDTQAVLPAVCT 917
Query: 486 AGYYNYPTCK-----PCNCDTSG-----TEPSICDDVSGQC--ICKAGFGGPRCD-QCLS 532
+ TCK CN D G T C +G C + + G + C
Sbjct: 918 PPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQK 977
Query: 533 GYYMQVLGRERQCVPCNCDP-TGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
GY G C DP + C C +T G +C +C Y D L
Sbjct: 978 GY----KGDGHSCT--EIDPCADGLNGGCHEHATCK-MTGPGKHKC-ECKSHY--VGDGL 1027
Query: 592 SCNCDVSGSIGSTCDDNGLCH 612
+C + I DNG CH
Sbjct: 1028 NCEPE-QLPIDRCLQDNGQCH 1047
Score = 60.9 bits (141), Expect = 8e-08
Identities = 61/235 (25%), Positives = 90/235 (38%), Gaps = 41/235 (17%)
Query: 439 CEDGYYSPECKNCECNT--VGSVSYVC-DKL--TGDCTCKSKYSGRTCNQCQAGYYNYPT 493
C G++ P+C+ C N V + +C D + TG C C +SG C C G Y
Sbjct: 201 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 260
Query: 494 CKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPT 553
+ C+C D G C C G+ G CD + NC+ T
Sbjct: 261 DQACSCVHGRCNQGPLGD--GSCDCDVGWRGVHCDNATT--------------EDNCNGT 304
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYY-KYPDCLSCN-CDVS-GSIGSTCD---- 606
TS NCLTN G +C+ G+ C + N C++S G + D
Sbjct: 305 CHTS--------ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT 356
Query: 607 --DNGLCHCKSNF--DGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSVPA 657
+C CK+ + DG C N+ C++ N + + A C +PA
Sbjct: 357 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDK-NAECTQTGPNQAACNCLPA 410
Score = 55.2 bits (127), Expect = 4e-06
Identities = 67/246 (27%), Positives = 91/246 (36%), Gaps = 49/246 (19%)
Query: 1796 CMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEYC 1855
C GY G RDC C P NN + D + + C C G+ G CE C
Sbjct: 815 CCKGYFG-------RDCQACPGGPDAPCNNRGVCLD--QYSATGECKCNTGFNGTACEMC 865
Query: 1856 AAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCD---SINGDCLKCVNNTAGAACN- 1911
G +G P+ C PC CS D G CD + +G CL C G +C+
Sbjct: 866 WPGRFG-PD---------CLPCGCS------DHGQCDDGITGSGQCL-CETGWTGPSCDT 908
Query: 1912 ------LCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVIG-EKCDRCAPD 1964
+C P A +N T C C+ D + T C+ G K RC+
Sbjct: 909 QAVLPAVCTPPCSAHATCKENNT-CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 967
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
T + C+ C G + C + + CA G+ G C + A T G C
Sbjct: 968 ----GTKVSCS-CQKGYKGDGHSCTEID---PCADGLNG-GCHEHAT--CKMTGPGKHKC 1016
Query: 2025 NCNTGY 2030
C + Y
Sbjct: 1017 ECKSHY 1022
Score = 55.2 bits (127), Expect = 4e-06
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 38/190 (20%)
Query: 1357 GQCPCKPNVIGRTCSACRTGYYGFPNCRPCHCPSTAICDD----NGMCICPKNVEGENCD 1412
G+C C G C C G +G P+C PC C CDD +G C+C G +CD
Sbjct: 849 GECKCNTGFNGTACEMCWPGRFG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD 907
Query: 1413 R-------CKPYTFNFDVQRGCDDCNCNPLGVVGNQLQ------CEADSGKCA--CRENV 1457
C P + + C CN L G+ + C+ D+G CA R +
Sbjct: 908 TQAVLPAVCTPPCSAHATCKENNTCECN-LDYEGDGITCTVVDFCKQDNGGCAKVARCSQ 966
Query: 1458 RG-RVCDHCVPGHYAFPDCYQCT------------CNRHGTTYDVCDQNTAQCYCKTNVR 1504
+G +V C G+ D + CT C+ H T + +C CK++
Sbjct: 967 KGTKVSCSCQKGYKG--DGHSCTEIDPCADGLNGGCHEHATC-KMTGPGKHKCECKSHYV 1023
Query: 1505 GQACDTCKEE 1514
G + C+ E
Sbjct: 1024 GDGLN-CEPE 1032
Score = 54.0 bits (124), Expect = 1e-05
Identities = 72/281 (25%), Positives = 100/281 (35%), Gaps = 35/281 (12%)
Query: 393 CAYGYFDYPNCKPC------TCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSP 446
C G+F P C+PC C NG + T G+C C ++G +CE C +G Y
Sbjct: 201 CCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGT-GVCECGEGFSGTACETCTEGKYGI 258
Query: 447 ECKNCECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTC-KPCNCDTSGTE 505
C C+ V G C C + G C+ TC NC T+
Sbjct: 259 HCDQA-CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN--- 314
Query: 506 PSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVL-GRERQCVPCNCDPTGSTSTSCSA-- 562
D + C C AGF G C + ++ G C G +C A
Sbjct: 315 ----SDGTASCKCAAGFQG-NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY 369
Query: 563 --DG----KCN-CLTNFGGAQCDQCSPGYYKYPDCLSCNC-DVSGSIGSTCDDNGLCHCK 614
DG + N CL N GG CD+ + P+ +CNC G C +C K
Sbjct: 370 TGDGIVCLEINPCLENHGG--CDKNAECTQTGPNQAACNCLPAYTGDGKVCTLIYVCLTK 427
Query: 615 SNFDGAKCDTCREQFYNYPACEECNCDPRGVTASFAGCGSV 655
N ++ C + C C P + F GS+
Sbjct: 428 -NGGCSEFAICN---HTGQVERTCTCKPNYIGDGFTCRGSI 464
Score = 51.2 bits (117), Expect = 7e-05
Identities = 73/284 (25%), Positives = 98/284 (34%), Gaps = 39/284 (13%)
Query: 358 CQPCQCDPH---FSTGNCEEE---SGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLN 411
CQPC + F G C + +G CEC F C +C G + + C+C ++
Sbjct: 210 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 268
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G + DG C C + G C D + + N C+T + D T C
Sbjct: 269 GRCNQG-PLGDGSCDCDVGWRGVHC----DNATTEDNCNGTCHTSANCLTNSDG-TASCK 322
Query: 472 CKSKY--SGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQ 529
C + + +G C A + C D T P C CKAG+ G
Sbjct: 323 CAAGFQGNGTICTAINACEISNGGCS-AKADCKRTTPG-----RRVCTCKAGYTGDGI-V 375
Query: 530 CLSGYYMQVLGRERQC-VPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYP 588
CL L C C TG + CNCL + G C+ Y
Sbjct: 376 CLE--INPCLENHGGCDKNAECTQTGPNQAA------CNCLPAYTG-DGKVCTLIYV--- 423
Query: 589 DCLSCN--CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQFY 630
CL+ N C T C CK N+ G TCR Y
Sbjct: 424 -CLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGF-TCRGSIY 465
Score = 51.2 bits (117), Expect = 7e-05
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 31/180 (17%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
C GY+G +C+ C A C++ G+C+ C G C+ C P F D
Sbjct: 815 CCKGYFG-RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 873
Query: 1423 VQRGCDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNR 1482
C C C+ G + + SG+C C G CD P C+
Sbjct: 874 ----CLPCGCSDHGQCDDGI---TGSGQCLCETGWTGPSCD----TQAVLPAVCTPPCSA 922
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEYFNLQDDNPDGCTK-CFCFGKTTRCSSS 1541
H T C +N C C + G TC F QD+ GC K C K T+ S S
Sbjct: 923 HAT----CKENNT-CECNLDYEGDGI-TCTVVDFCKQDNG--GCAKVARCSQKGTKVSCS 974
Score = 48.4 bits (110), Expect = 5e-04
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 36/192 (18%)
Query: 1320 GLCREAMFSITSEYNSGA-----RPCLCD--FMGSTELECNTFGGQCPCKPNVIGRTCSA 1372
G CR +T + + + R C+ FMG L G Q C VI R C A
Sbjct: 147 GRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTL---FIGCQPKCVRTVITRECCA 203
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI----------CPKNVEGENCDRCKPYTFNFD 1422
G++G P C+PC + +C NG+C+ C + G C+ C +
Sbjct: 204 ---GFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 259
Query: 1423 VQRGCDD-CNCNPLGVVGNQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCY---QC 1478
CD C+C V G Q G C C RG CD+ C+ C
Sbjct: 260 ----CDQACSC----VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC 311
Query: 1479 TCNRHGTTYDVC 1490
N GT C
Sbjct: 312 LTNSDGTASCKC 323
Score = 47.2 bits (107), Expect = 0.001
Identities = 58/219 (26%), Positives = 77/219 (35%), Gaps = 31/219 (14%)
Query: 568 CLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCRE 627
C F G QC C PG + C + G G+ G+C C F G C+TC E
Sbjct: 201 CCAGFFGPQCQPC-PGNAQNV-CFGNGICLDGVNGT-----GVCECGEGFSGTACETCTE 253
Query: 628 QFYNYPACEECNCDPRGVTASFAGCGSVPAG---ELCQCKDRVQGRICNDCKPLYWNLQE 684
Y + C+C G GS C + CN N
Sbjct: 254 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLT 313
Query: 685 YNPFGCEQCNCNLA----GTL-NSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRL 735
N G C C GT+ ++ AC +G C CK+ R+ C G+
Sbjct: 314 -NSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--- 369
Query: 736 QTNDVFGCTECD-C-DIGGSIDNNCDKT-TG----QCHC 767
T D C E + C + G D N + T TG C+C
Sbjct: 370 -TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC 407
Score = 46.8 bits (106), Expect = 0.001
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 33/140 (23%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCD---VNTGICLNCADNTIGD 1791
EC+C + G +CE C G + P C+PC C+ H QCD +G CL C G
Sbjct: 850 ECKCNTGFNGTACEMCWPGRFG-PD--CLPCGCSDHG-QCDDGITGSGQCL-CETGWTGP 904
Query: 1792 HCE-------FCMSGYHGDATVGTPRDCLICACPMPYPSNNFALS----CD--------- 1831
C+ C AT ++ C C + Y + + C
Sbjct: 905 SCDTQAVLPAVCTPPCSAHATC---KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKV 961
Query: 1832 --LSENGSLISCNCQPGYGG 1849
S+ G+ +SC+CQ GY G
Sbjct: 962 ARCSQKGTKVSCSCQKGYKG 981
Score = 42.7 bits (96), Expect = 0.024
Identities = 59/225 (26%), Positives = 81/225 (36%), Gaps = 38/225 (16%)
Query: 576 QCDQCSPGYYKYPDCLSCN------CDVSGSIGSTCDDNGLCHCKSNFDGAKCDTCREQF 629
Q +C GY+ DC +C C+ G G C C + F+G C+ C
Sbjct: 811 QIPRCCKGYFGR-DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR 869
Query: 630 YNYPACEECNCDPR-----GVTAS-FAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQ 683
+ P C C C G+T S C + G C + V +C + +
Sbjct: 870 FG-PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQ-AVLPAVCTPPCSAHATCK 927
Query: 684 EYNPFGCEQCNCNLAG---TLNSLGACNTKSGQCV----CKQHVGERQCDQCLDGFYRLQ 736
E N CE CN + G T + C +G C C Q + C C G+
Sbjct: 928 ENNT--CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC-SCQKGY---- 979
Query: 737 TNDVFGCTECD-CD---IGGSIDNNCDKTTG----QCHCHSRVEG 773
D CTE D C GG ++ K TG +C C S G
Sbjct: 980 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 1024
Score = 41.5 bits (93), Expect = 0.056
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 1932 CDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDD 1991
CD F D G+CV P C R + L P + +C
Sbjct: 755 CDTFTTFDASGECGSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLV 809
Query: 1992 NGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGE 2051
RC KG G+ C C G D CN N G + +ATG+C+C G G
Sbjct: 810 IQIPRCCKGYFGRDCQACPGG-----PDA--PCN-NRGVCLD-QYSATGECKCNTGFNGT 860
Query: 2052 KCDRCPERWVLIPQEGCLECDSCTD 2076
C+ C W CL C C+D
Sbjct: 861 ACEMC---WPGRFGPDCLPC-GCSD 881
Score = 38.7 bits (86), Expect = 0.39
Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 11/94 (11%)
Query: 1427 CDDCNCNPLGVV-GNQLQCEA--DSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRH 1483
C C N V GN + + +G C C E G C+ C G Y C+C H
Sbjct: 210 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSC-VH 268
Query: 1484 GTTYDVCDQ---NTAQCYCKTNVRGQACDTCKEE 1514
G C+Q C C RG CD E
Sbjct: 269 GR----CNQGPLGDGSCDCDVGWRGVHCDNATTE 298
Score = 35.1 bits (77), Expect = 4.8
Identities = 21/80 (26%), Positives = 28/80 (35%), Gaps = 6/80 (7%)
Query: 1457 VRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYD--VC---DQNTAQCYCKTNVRGQACDTC 1511
VR + C G + P C C N + +C T C C G AC+TC
Sbjct: 193 VRTVITRECCAGFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETC 251
Query: 1512 KEEYFNLQDDNPDGCTKCFC 1531
E + + D C C
Sbjct: 252 TEGKYGIHCDQACSCVHGRC 271
>AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 74.5 bits (175), Expect = 6e-12
Identities = 54/177 (30%), Positives = 78/177 (44%), Gaps = 34/177 (19%)
Query: 421 TDGLCP----CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD-----C 470
T CP C + SC +C+ GY C + C N ++ C + G C
Sbjct: 1877 TSSPCPPNSRCHDAWEDYSC-VCDKGYLGINCVDACHLNPCENMG-ACVRSPGSPQGYVC 1934
Query: 471 TCKSKYSGRTCNQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGG 524
C + G C C G++ P C PC+C S G +P C+ +GQC
Sbjct: 1935 ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPD-CNKTNGQC-------- 1985
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQC 580
QC YY ++L ++ C+PC+C P GS S +C A G+C C G QC++C
Sbjct: 1986 ----QCKENYY-KLLAQDT-CLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 74.1 bits (174), Expect = 9e-12
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 25/186 (13%)
Query: 353 DELDVCQPCQCDPHFSTGNCEE--ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNL 410
D DV PC P C + E C C + +C D + PC N+
Sbjct: 1868 DGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC-------VDACHLNPCE-NM 1919
Query: 411 NGTEGEHCTPTDGLCPCKYNYAGKSCEI-----CEDGYY-SPECKNCECNTVGSVSYVCD 464
+P +C C ++ G CE C G++ +P C C C C+
Sbjct: 1920 GACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPDCN 1979
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
K G C CK Y TC PC+C G+ CD +GQC CK G G
Sbjct: 1980 KTNGQCQCKENYYKLLAQD---------TCLPCDCFPHGSHSRTCDMATGQCACKPGVIG 2030
Query: 525 PRCDQC 530
+C++C
Sbjct: 2031 RQCNRC 2036
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/191 (28%), Positives = 80/191 (41%), Gaps = 32/191 (16%)
Query: 595 CDVSGSIGST-CDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP-RGVTASFAGC 652
CDV S+ C N CH ++ C C + + + C+ +P + A
Sbjct: 1870 CDVDDPCTSSPCPPNSRCH--DAWEDYSC-VCDKGYLGINCVDACHLNPCENMGACVRSP 1926
Query: 653 GSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
GS P G +C+C G C + C +W NP C C+C ++ + C
Sbjct: 1927 GS-PQGYVCECGPSHYGPYCENKLDLPCPRGWWG----NPV-CGPCHCAVSKGFDP--DC 1978
Query: 708 NTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
N +GQC CK++ +Y+L D C CDC GS CD TGQC C
Sbjct: 1979 NKTNGQCQCKEN------------YYKLLAQDT--CLPCDCFPHGSHSRTCDMATGQCAC 2024
Query: 768 HSRVEGRRCDQ 778
V GR+C++
Sbjct: 2025 KPGVIGRQCNR 2035
Score = 65.3 bits (152), Expect = 4e-09
Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 21/129 (16%)
Query: 1947 CVCRPGVIGEKCDR-----CAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNGQCRCAKG 2000
C C P G C+ C WG C PC+C ++ C+ NGQC+C +
Sbjct: 1934 CECGPSHYGPYCENKLDLPCPRGWWGNPV---CGPCHCAVSKGFDPDCNKTNGQCQCKEN 1990
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPER 2059
+ +D C C+C S C+ ATGQC C PGVIG +C+RC
Sbjct: 1991 Y-----------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNP 2039
Query: 2060 WVLIPQEGC 2068
+ + GC
Sbjct: 2040 FAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 29/171 (16%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGY-GGARCEYCAAGYYG--------IPED 1865
C C Y N +C L+ ++ +C PG G CE C +YG +P
Sbjct: 1896 CVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCP 1954
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
C PC+C+ + DP C+ NG C +C N Y +
Sbjct: 1955 RGWWGNPVCGPCHCAVS-KGFDP-DCNKTNGQC-QCKEN-------------YYKLLAQD 1998
Query: 1926 NCTACICDEFG--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGC 1974
C C C G CD TG C C+PGVIG +C+RC + + T LGC
Sbjct: 1999 TCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC-DNPFAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 21/191 (10%)
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
C+++ G C++ + G C C P YG +K C +G C G C C
Sbjct: 1916 CENM-GACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCPRGWWGNPVC----GPCHCA 1969
Query: 1951 PGV-IGEKCDR------CAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVT 2002
C++ C +++ L C PC+C S S CD GQC C GV
Sbjct: 1970 VSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVI 2029
Query: 2003 GKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT--GQCECLP---GVIGEKCDR 2055
G+QC++C F T GC+ + C + G T GQ +P G +G
Sbjct: 2030 GRQCNRCDNPFAEVTTLGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRH 2089
Query: 2056 CPERWVLIPQE 2066
C +P E
Sbjct: 2090 CSGEKGWLPPE 2100
Score = 61.7 bits (143), Expect = 5e-08
Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 20/143 (13%)
Query: 320 EGGGKCLNCQHNTEGINCNKCRPTYYRPYGKR---------WDELDVCQPCQCDPHFSTG 370
E G C+ + +G C +C P++Y PY + W VC PC C
Sbjct: 1917 ENMGACVRSPGSPQGYVC-ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFD 1975
Query: 371 -NCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKY 429
+C + +G+C+C+ + Y C PC C +G+ C G C CK
Sbjct: 1976 PDCNKTNGQCQCKENY---------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKP 2026
Query: 430 NYAGKSCEICEDGYYSPECKNCE 452
G+ C C++ + CE
Sbjct: 2027 GVIGRQCNRCDNPFAEVTTLGCE 2049
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/158 (28%), Positives = 61/158 (38%), Gaps = 30/158 (18%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI-CPKNVEGENCD----RCKPYTFN---FDVQ 1424
C GY G CH C++ G C+ P + +G C+ PY N
Sbjct: 1898 CDKGYLGINCVDACHLNP---CENMGACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCP 1954
Query: 1425 RG------CDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQ 1477
RG C C+C G C +G+C C+EN + D C+P
Sbjct: 1955 RGWWGNPVCGPCHCAVSK--GFDPDCNKTNGQCQCKENYYKLLAQDTCLP---------- 2002
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C HG+ CD T QC CK V G+ C+ C +
Sbjct: 2003 CDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNPF 2040
Score = 50.0 bits (114), Expect = 2e-04
Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 28/197 (14%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS-IGSTCD 606
C+ D TS+ C + +C+ CD+ G C C+ G+ + S
Sbjct: 1870 CDVDDP-CTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGS 1928
Query: 607 DNG-LCHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G +C C + G C+ C ++ P C C+C V+ F + G+
Sbjct: 1929 PQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHC---AVSKGFDPDCNKTNGQ- 1984
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
CQCK+ + D C C+C G+ + C+ +GQC CK V
Sbjct: 1985 CQCKENYYKLLAQDT--------------CLPCDCFPHGSHSR--TCDMATGQCACKPGV 2028
Query: 721 GERQCDQCLDGFYRLQT 737
RQC++C + F + T
Sbjct: 2029 IGRQCNRCDNPFAEVTT 2045
Score = 44.8 bits (101), Expect = 0.006
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
C+E + + ++ PC C GS C+ GQC CKP VIGR C+ C
Sbjct: 1987 CKENYYKLLAQ--DTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 43.6 bits (98), Expect = 0.014
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPN----VIGRTCSACRTGYYGFPNCRPCHCPSTAIC 1394
PC C + +CN GQC CK N + TC C +C P H + C
Sbjct: 1965 PCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPC--------DCFP-HGSHSRTC 2015
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D G C C V G C+RC
Sbjct: 2016 DMATGQCACKPGVIGRQCNRC 2036
Score = 34.3 bits (75), Expect = 8.4
Identities = 14/35 (40%), Positives = 23/35 (65%)
Query: 2981 VPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC 3015
V +R F GCMR +S++G N+D++ + + G GC
Sbjct: 1612 VHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGC 1646
>AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 74.5 bits (175), Expect = 6e-12
Identities = 54/177 (30%), Positives = 78/177 (44%), Gaps = 34/177 (19%)
Query: 421 TDGLCP----CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD-----C 470
T CP C + SC +C+ GY C + C N ++ C + G C
Sbjct: 1877 TSSPCPPNSRCHDAWEDYSC-VCDKGYLGINCVDACHLNPCENMG-ACVRSPGSPQGYVC 1934
Query: 471 TCKSKYSGRTCNQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGG 524
C + G C C G++ P C PC+C S G +P C+ +GQC
Sbjct: 1935 ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPD-CNKTNGQC-------- 1985
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQC 580
QC YY ++L ++ C+PC+C P GS S +C A G+C C G QC++C
Sbjct: 1986 ----QCKENYY-KLLAQDT-CLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 74.1 bits (174), Expect = 9e-12
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 25/186 (13%)
Query: 353 DELDVCQPCQCDPHFSTGNCEE--ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNL 410
D DV PC P C + E C C + +C D + PC N+
Sbjct: 1868 DGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC-------VDACHLNPCE-NM 1919
Query: 411 NGTEGEHCTPTDGLCPCKYNYAGKSCEI-----CEDGYY-SPECKNCECNTVGSVSYVCD 464
+P +C C ++ G CE C G++ +P C C C C+
Sbjct: 1920 GACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPDCN 1979
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
K G C CK Y TC PC+C G+ CD +GQC CK G G
Sbjct: 1980 KTNGQCQCKENYYKLLAQD---------TCLPCDCFPHGSHSRTCDMATGQCACKPGVIG 2030
Query: 525 PRCDQC 530
+C++C
Sbjct: 2031 RQCNRC 2036
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/191 (28%), Positives = 80/191 (41%), Gaps = 32/191 (16%)
Query: 595 CDVSGSIGST-CDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP-RGVTASFAGC 652
CDV S+ C N CH ++ C C + + + C+ +P + A
Sbjct: 1870 CDVDDPCTSSPCPPNSRCH--DAWEDYSC-VCDKGYLGINCVDACHLNPCENMGACVRSP 1926
Query: 653 GSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
GS P G +C+C G C + C +W NP C C+C ++ + C
Sbjct: 1927 GS-PQGYVCECGPSHYGPYCENKLDLPCPRGWWG----NPV-CGPCHCAVSKGFDP--DC 1978
Query: 708 NTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
N +GQC CK++ +Y+L D C CDC GS CD TGQC C
Sbjct: 1979 NKTNGQCQCKEN------------YYKLLAQDT--CLPCDCFPHGSHSRTCDMATGQCAC 2024
Query: 768 HSRVEGRRCDQ 778
V GR+C++
Sbjct: 2025 KPGVIGRQCNR 2035
Score = 65.3 bits (152), Expect = 4e-09
Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 21/129 (16%)
Query: 1947 CVCRPGVIGEKCDR-----CAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNGQCRCAKG 2000
C C P G C+ C WG C PC+C ++ C+ NGQC+C +
Sbjct: 1934 CECGPSHYGPYCENKLDLPCPRGWWGNPV---CGPCHCAVSKGFDPDCNKTNGQCQCKEN 1990
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPER 2059
+ +D C C+C S C+ ATGQC C PGVIG +C+RC
Sbjct: 1991 Y-----------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNP 2039
Query: 2060 WVLIPQEGC 2068
+ + GC
Sbjct: 2040 FAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 29/171 (16%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGY-GGARCEYCAAGYYG--------IPED 1865
C C Y N +C L+ ++ +C PG G CE C +YG +P
Sbjct: 1896 CVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCP 1954
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
C PC+C+ + DP C+ NG C +C N Y +
Sbjct: 1955 RGWWGNPVCGPCHCAVS-KGFDP-DCNKTNGQC-QCKEN-------------YYKLLAQD 1998
Query: 1926 NCTACICDEFG--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGC 1974
C C C G CD TG C C+PGVIG +C+RC + + T LGC
Sbjct: 1999 TCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC-DNPFAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 21/191 (10%)
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
C+++ G C++ + G C C P YG +K C +G C G C C
Sbjct: 1916 CENM-GACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCPRGWWGNPVC----GPCHCA 1969
Query: 1951 PGV-IGEKCDR------CAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVT 2002
C++ C +++ L C PC+C S S CD GQC C GV
Sbjct: 1970 VSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVI 2029
Query: 2003 GKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT--GQCECLP---GVIGEKCDR 2055
G+QC++C F T GC+ + C + G T GQ +P G +G
Sbjct: 2030 GRQCNRCDNPFAEVTTLGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRH 2089
Query: 2056 CPERWVLIPQE 2066
C +P E
Sbjct: 2090 CSGEKGWLPPE 2100
Score = 61.7 bits (143), Expect = 5e-08
Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 20/143 (13%)
Query: 320 EGGGKCLNCQHNTEGINCNKCRPTYYRPYGKR---------WDELDVCQPCQCDPHFSTG 370
E G C+ + +G C +C P++Y PY + W VC PC C
Sbjct: 1917 ENMGACVRSPGSPQGYVC-ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFD 1975
Query: 371 -NCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKY 429
+C + +G+C+C+ + Y C PC C +G+ C G C CK
Sbjct: 1976 PDCNKTNGQCQCKENY---------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKP 2026
Query: 430 NYAGKSCEICEDGYYSPECKNCE 452
G+ C C++ + CE
Sbjct: 2027 GVIGRQCNRCDNPFAEVTTLGCE 2049
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/158 (28%), Positives = 61/158 (38%), Gaps = 30/158 (18%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI-CPKNVEGENCD----RCKPYTFN---FDVQ 1424
C GY G CH C++ G C+ P + +G C+ PY N
Sbjct: 1898 CDKGYLGINCVDACHLNP---CENMGACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCP 1954
Query: 1425 RG------CDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQ 1477
RG C C+C G C +G+C C+EN + D C+P
Sbjct: 1955 RGWWGNPVCGPCHCAVSK--GFDPDCNKTNGQCQCKENYYKLLAQDTCLP---------- 2002
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C HG+ CD T QC CK V G+ C+ C +
Sbjct: 2003 CDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNPF 2040
Score = 50.0 bits (114), Expect = 2e-04
Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 28/197 (14%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS-IGSTCD 606
C+ D TS+ C + +C+ CD+ G C C+ G+ + S
Sbjct: 1870 CDVDDP-CTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGS 1928
Query: 607 DNG-LCHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G +C C + G C+ C ++ P C C+C V+ F + G+
Sbjct: 1929 PQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHC---AVSKGFDPDCNKTNGQ- 1984
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
CQCK+ + D C C+C G+ + C+ +GQC CK V
Sbjct: 1985 CQCKENYYKLLAQDT--------------CLPCDCFPHGSHSR--TCDMATGQCACKPGV 2028
Query: 721 GERQCDQCLDGFYRLQT 737
RQC++C + F + T
Sbjct: 2029 IGRQCNRCDNPFAEVTT 2045
Score = 44.8 bits (101), Expect = 0.006
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
C+E + + ++ PC C GS C+ GQC CKP VIGR C+ C
Sbjct: 1987 CKENYYKLLAQ--DTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 43.6 bits (98), Expect = 0.014
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPN----VIGRTCSACRTGYYGFPNCRPCHCPSTAIC 1394
PC C + +CN GQC CK N + TC C +C P H + C
Sbjct: 1965 PCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPC--------DCFP-HGSHSRTC 2015
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D G C C V G C+RC
Sbjct: 2016 DMATGQCACKPGVIGRQCNRC 2036
Score = 34.3 bits (75), Expect = 8.4
Identities = 14/35 (40%), Positives = 23/35 (65%)
Query: 2981 VPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC 3015
V +R F GCMR +S++G N+D++ + + G GC
Sbjct: 1612 VHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGC 1646
>AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 74.5 bits (175), Expect = 6e-12
Identities = 54/177 (30%), Positives = 78/177 (44%), Gaps = 34/177 (19%)
Query: 421 TDGLCP----CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD-----C 470
T CP C + SC +C+ GY C + C N ++ C + G C
Sbjct: 1877 TSSPCPPNSRCHDAWEDYSC-VCDKGYLGINCVDACHLNPCENMG-ACVRSPGSPQGYVC 1934
Query: 471 TCKSKYSGRTCNQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGG 524
C + G C C G++ P C PC+C S G +P C+ +GQC
Sbjct: 1935 ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPD-CNKTNGQC-------- 1985
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQC 580
QC YY ++L ++ C+PC+C P GS S +C A G+C C G QC++C
Sbjct: 1986 ----QCKENYY-KLLAQDT-CLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 74.1 bits (174), Expect = 9e-12
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 25/186 (13%)
Query: 353 DELDVCQPCQCDPHFSTGNCEE--ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNL 410
D DV PC P C + E C C + +C D + PC N+
Sbjct: 1868 DGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC-------VDACHLNPCE-NM 1919
Query: 411 NGTEGEHCTPTDGLCPCKYNYAGKSCEI-----CEDGYY-SPECKNCECNTVGSVSYVCD 464
+P +C C ++ G CE C G++ +P C C C C+
Sbjct: 1920 GACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPDCN 1979
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
K G C CK Y TC PC+C G+ CD +GQC CK G G
Sbjct: 1980 KTNGQCQCKENYYKLLAQD---------TCLPCDCFPHGSHSRTCDMATGQCACKPGVIG 2030
Query: 525 PRCDQC 530
+C++C
Sbjct: 2031 RQCNRC 2036
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/191 (28%), Positives = 80/191 (41%), Gaps = 32/191 (16%)
Query: 595 CDVSGSIGST-CDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP-RGVTASFAGC 652
CDV S+ C N CH ++ C C + + + C+ +P + A
Sbjct: 1870 CDVDDPCTSSPCPPNSRCH--DAWEDYSC-VCDKGYLGINCVDACHLNPCENMGACVRSP 1926
Query: 653 GSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
GS P G +C+C G C + C +W NP C C+C ++ + C
Sbjct: 1927 GS-PQGYVCECGPSHYGPYCENKLDLPCPRGWWG----NPV-CGPCHCAVSKGFDP--DC 1978
Query: 708 NTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
N +GQC CK++ +Y+L D C CDC GS CD TGQC C
Sbjct: 1979 NKTNGQCQCKEN------------YYKLLAQDT--CLPCDCFPHGSHSRTCDMATGQCAC 2024
Query: 768 HSRVEGRRCDQ 778
V GR+C++
Sbjct: 2025 KPGVIGRQCNR 2035
Score = 65.3 bits (152), Expect = 4e-09
Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 21/129 (16%)
Query: 1947 CVCRPGVIGEKCDR-----CAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNGQCRCAKG 2000
C C P G C+ C WG C PC+C ++ C+ NGQC+C +
Sbjct: 1934 CECGPSHYGPYCENKLDLPCPRGWWGNPV---CGPCHCAVSKGFDPDCNKTNGQCQCKEN 1990
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPER 2059
+ +D C C+C S C+ ATGQC C PGVIG +C+RC
Sbjct: 1991 Y-----------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNP 2039
Query: 2060 WVLIPQEGC 2068
+ + GC
Sbjct: 2040 FAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 29/171 (16%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGY-GGARCEYCAAGYYG--------IPED 1865
C C Y N +C L+ ++ +C PG G CE C +YG +P
Sbjct: 1896 CVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCP 1954
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
C PC+C+ + DP C+ NG C +C N Y +
Sbjct: 1955 RGWWGNPVCGPCHCAVS-KGFDP-DCNKTNGQC-QCKEN-------------YYKLLAQD 1998
Query: 1926 NCTACICDEFG--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGC 1974
C C C G CD TG C C+PGVIG +C+RC + + T LGC
Sbjct: 1999 TCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC-DNPFAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 21/191 (10%)
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
C+++ G C++ + G C C P YG +K C +G C G C C
Sbjct: 1916 CENM-GACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCPRGWWGNPVC----GPCHCA 1969
Query: 1951 PGV-IGEKCDR------CAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVT 2002
C++ C +++ L C PC+C S S CD GQC C GV
Sbjct: 1970 VSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVI 2029
Query: 2003 GKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT--GQCECLP---GVIGEKCDR 2055
G+QC++C F T GC+ + C + G T GQ +P G +G
Sbjct: 2030 GRQCNRCDNPFAEVTTLGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRH 2089
Query: 2056 CPERWVLIPQE 2066
C +P E
Sbjct: 2090 CSGEKGWLPPE 2100
Score = 61.7 bits (143), Expect = 5e-08
Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 20/143 (13%)
Query: 320 EGGGKCLNCQHNTEGINCNKCRPTYYRPYGKR---------WDELDVCQPCQCDPHFSTG 370
E G C+ + +G C +C P++Y PY + W VC PC C
Sbjct: 1917 ENMGACVRSPGSPQGYVC-ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFD 1975
Query: 371 -NCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKY 429
+C + +G+C+C+ + Y C PC C +G+ C G C CK
Sbjct: 1976 PDCNKTNGQCQCKENY---------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKP 2026
Query: 430 NYAGKSCEICEDGYYSPECKNCE 452
G+ C C++ + CE
Sbjct: 2027 GVIGRQCNRCDNPFAEVTTLGCE 2049
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/158 (28%), Positives = 61/158 (38%), Gaps = 30/158 (18%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI-CPKNVEGENCD----RCKPYTFN---FDVQ 1424
C GY G CH C++ G C+ P + +G C+ PY N
Sbjct: 1898 CDKGYLGINCVDACHLNP---CENMGACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCP 1954
Query: 1425 RG------CDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQ 1477
RG C C+C G C +G+C C+EN + D C+P
Sbjct: 1955 RGWWGNPVCGPCHCAVSK--GFDPDCNKTNGQCQCKENYYKLLAQDTCLP---------- 2002
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C HG+ CD T QC CK V G+ C+ C +
Sbjct: 2003 CDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNPF 2040
Score = 50.0 bits (114), Expect = 2e-04
Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 28/197 (14%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS-IGSTCD 606
C+ D TS+ C + +C+ CD+ G C C+ G+ + S
Sbjct: 1870 CDVDDP-CTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGS 1928
Query: 607 DNG-LCHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G +C C + G C+ C ++ P C C+C V+ F + G+
Sbjct: 1929 PQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHC---AVSKGFDPDCNKTNGQ- 1984
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
CQCK+ + D C C+C G+ + C+ +GQC CK V
Sbjct: 1985 CQCKENYYKLLAQDT--------------CLPCDCFPHGSHSR--TCDMATGQCACKPGV 2028
Query: 721 GERQCDQCLDGFYRLQT 737
RQC++C + F + T
Sbjct: 2029 IGRQCNRCDNPFAEVTT 2045
Score = 44.8 bits (101), Expect = 0.006
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
C+E + + ++ PC C GS C+ GQC CKP VIGR C+ C
Sbjct: 1987 CKENYYKLLAQ--DTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 43.6 bits (98), Expect = 0.014
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPN----VIGRTCSACRTGYYGFPNCRPCHCPSTAIC 1394
PC C + +CN GQC CK N + TC C +C P H + C
Sbjct: 1965 PCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPC--------DCFP-HGSHSRTC 2015
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D G C C V G C+RC
Sbjct: 2016 DMATGQCACKPGVIGRQCNRC 2036
Score = 34.3 bits (75), Expect = 8.4
Identities = 14/35 (40%), Positives = 23/35 (65%)
Query: 2981 VPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC 3015
V +R F GCMR +S++G N+D++ + + G GC
Sbjct: 1612 VHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGC 1646
>AJ316284-1|CAC87720.2| 1392|Homo sapiens neurexin 3-alpha protein.
Length = 1392
Score = 74.5 bits (175), Expect = 6e-12
Identities = 75/344 (21%), Positives = 157/344 (45%), Gaps = 37/344 (10%)
Query: 2870 SNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGN-TEDLIIVGTTRAYND 2928
S+++ L F+T+ NGLI G+ + +L ++DG V L ++LG+ + I+ +ND
Sbjct: 278 SDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFND 337
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGILQVP----DR 2984
WH + R L + +++VD + + D + G + +P
Sbjct: 338 NAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN 397
Query: 2985 GFDGCMRQI--SINGVNLDLSE-------NLESIG-MAYGCQ-FASL--VSFNGTDSYLR 3031
F GC++++ N + L+LS ++ G + + C+ A+L ++F ++Y+
Sbjct: 398 NFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINFETPEAYIS 457
Query: 3032 FVD-VTSENPQLTLKFKTAKPNGL-LFVY-------VSRTQTAIMPDSISLSLVNGKLVV 3082
T ++ F+T +PNGL LF + +R+Q D ++ L++G L +
Sbjct: 458 LPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYL 517
Query: 3083 V----SQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGV 3138
+ S ++ ND +W+ + + + + + V+ T + + L+G
Sbjct: 518 LLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGD 577
Query: 3139 LFIGGV---QPGYVVSGSLGSKV---PFTGCIGDATINGQVLNL 3176
+++GG+ + G ++ L + + + GCI D I+G+ N+
Sbjct: 578 MYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNI 621
Score = 60.5 bits (140), Expect = 1e-07
Identities = 73/299 (24%), Positives = 124/299 (41%), Gaps = 30/299 (10%)
Query: 2898 LLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESN 2957
L + GRV L V+LG + + G + ND +WH + R LTVD++V +
Sbjct: 734 LELDGGRVKLMVNLGKGPETLYAG--QKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMV 791
Query: 2958 SPSADIPSLDTMNFGGNNKGILQVPDRGFDGCMRQISING-VNLDLSENLE----SIGMA 3012
+ + K + V F G ++ + NG + +DL +N + +
Sbjct: 792 GDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKAR 851
Query: 3013 YGCQ--FASLVSFNGTDSYLRFVDVTS-ENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPD 3069
+G + A V+F SYL + + + L +FKT P+G + + D
Sbjct: 852 FGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILF-----NSGDGND 906
Query: 3070 SISLSLVNGKLVVVSQREQLDTGLNT--------YNDSQWHVLTVTH-NTSALKLVVDDF 3120
I++ LV G + V L G N ND+QWH + +T N++ L VD
Sbjct: 907 FIAVELVKGYIHYVF---DLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTK 963
Query: 3121 DYFSTDTAPPPLHILDGVLFIGGVQPGYV--VSGSLGSKVPFTGCIGDATINGQVLNLL 3177
L L G L++ G+ G + + S+ F GC+ +NG++ +L+
Sbjct: 964 VVTQVINGAKNLD-LKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLI 1021
Score = 58.8 bits (136), Expect = 3e-07
Identities = 94/401 (23%), Positives = 175/401 (43%), Gaps = 59/401 (14%)
Query: 2660 STSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS-E 2718
S+S ++ F+T +++G IL+ G KS DY+ + +++G +V+++G + E
Sbjct: 276 SSSDEITLSFKTWQRNGLILHTG----------KSADYVNLALKDGAVSLVINLGSGAFE 325
Query: 2719 PGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIF 2778
+P + DN W+ V V R R+V +S+ L T T +++E +T+
Sbjct: 326 AIVEPVNGKFN----DNAWHDVKVTRNLRQVTISVDGIL---TTTGYTQE-----DYTML 373
Query: 2779 NLDKEKSKLYVGGVPSDAKLQGISFPA-FEGQIEELMIGDTPVGL----WNFVSANKLKG 2833
D YVGG PS A L G F G ++E++ + + L ++ K+K
Sbjct: 374 GSD---DFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKI 430
Query: 2834 ARQRDKLISSQSGPQEYRFDG-RGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLV-GE 2891
+ + + F+ Y ++ + T + + FRT PNGLI G+
Sbjct: 431 YGEVVFKCENVATLDPINFETPEAYISLPK--WNTKRMGSISFDFRTTEPNGLILFTHGK 488
Query: 2892 GGY-------------FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARR 2938
FF++ + DG +YL + +G+ + + T + NDG+W+ +D +R
Sbjct: 489 PQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGT-IKVKATQKKANDGEWYHVDIQR 547
Query: 2939 FLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG--NNKGILQVPDR--------GFDG 2988
+++V++ ++ S + M GG N+ L +P G+ G
Sbjct: 548 DGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVG 607
Query: 2989 CMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSY 3029
C+R + I+G + ++ + E A S +S DSY
Sbjct: 608 CIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSY 648
Score = 57.2 bits (132), Expect = 1e-06
Identities = 75/308 (24%), Positives = 135/308 (43%), Gaps = 30/308 (9%)
Query: 2720 GQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFN 2779
G+ P + + + DN W+ V V R G+ +KL++ + + GT + L H+
Sbjct: 748 GKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGT--MVGDHTRLEFHNIETG 805
Query: 2780 LDKEKSKLYVGGVPSDAKLQGISFPAFEGQIEELMI-GDTPVGLWNFVSANKLKGARQRD 2838
+ EK Y+ VPS +F G ++ LM G + L + + + R
Sbjct: 806 IMTEKR--YISVVPS----------SFIGHLQSLMFNGLLYIDLCKNGDIDYCE-LKARF 852
Query: 2839 KLISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLI-YLVGEGGYFFS 2897
L + + P ++ Y ++A T S + F+T +P+G I + G+G F +
Sbjct: 853 GLRNIIADPVTFKTKS-SYLSLATLQAYT--SMHLFFQFKTTSPDGFILFNSGDGNDFIA 909
Query: 2898 LLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKC-SLTVDNEVLKAES 2956
+ + G ++ LGN ++I + R ND +WH + R + SL VD +V+
Sbjct: 910 VELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVI 969
Query: 2957 NSPSADIPSLDTMNFGGNNKGILQ-----VPDR-GFDGCMRQISINGVNLDL-SENLESI 3009
N + ++ + G +G+ V R GF GC+ + +NG DL ++ L
Sbjct: 970 NG-AKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRS 1028
Query: 3010 G-MAYGCQ 3016
G + GC+
Sbjct: 1029 GQIERGCE 1036
Score = 55.6 bits (128), Expect = 3e-06
Identities = 72/336 (21%), Positives = 132/336 (39%), Gaps = 19/336 (5%)
Query: 3335 ISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYNDID 3394
+SFR ++ + A ++ D L + ++ M N G + + ND +
Sbjct: 707 VSFRFMSQRAYGLLVATTSRDS--ADTLRLELDGGRVKLMVNLGKGPETLYAGQKLNDNE 764
Query: 3395 WHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISKIFDNFYQ 3454
WHTV + R G KL VD ++ T V +T L G+ IS + +
Sbjct: 765 WHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEF--HNIETGIMTEKRYISVVPSS--- 819
Query: 3455 PFMGCLKGLLMNGQ---QVTRIGNA-VNALRCVDNIEDGVYFEASNNTHSNYLKLLENFK 3510
F+G L+ L+ NG + + G+ L+ + + + + T S+YL L +
Sbjct: 820 -FIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLS-LATLQ 877
Query: 3511 VGDEVSISMEVRPRNTTGLLLSVHGK-KDYMVLELLDSEVVANVENGNGPFRATYKLSNK 3569
+ + + + + G +L G D++ +EL+ + + GNGP K ++
Sbjct: 878 AYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGP--NVIKGNSD 935
Query: 3570 HYLCDGNWHK-IHXXXXXXXXXXXXDGHFSKPGIGAYTSTDTHSALYIGGHERPIHK--V 3626
L D WH + D I + D LY+ G + ++
Sbjct: 936 RPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLP 995
Query: 3627 RGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHV 3662
+ V SR GF GC+ ++ + + N A+ R +
Sbjct: 996 KLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQI 1031
Score = 49.2 bits (112), Expect = 3e-04
Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 6/148 (4%)
Query: 3513 DEVSISMEVRPRNTTGLLLSVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYL 3572
DE+++S + RN GL+L DY+ L L D V + G+G F A + N +
Sbjct: 279 DEITLSFKTWQRN--GLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKF- 335
Query: 3573 CDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA--YTSTDTHSALYIGGHERPIHKVRGVH 3630
D WH + DG + G YT + Y+GG + G
Sbjct: 336 NDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTA-DLPGSP 394
Query: 3631 SRRGFTGCVRNIVVGETPVKVPNSAVGR 3658
F GC++ +V +++ S + R
Sbjct: 395 VSNNFMGCLKEVVYKNNDIRLELSRLAR 422
Score = 48.4 bits (110), Expect = 5e-04
Identities = 67/280 (23%), Positives = 109/280 (38%), Gaps = 47/280 (16%)
Query: 3332 DLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGG---ETGVISSTH 3388
++T+SF+T+ + G ++ +SA ++ ++D + + N G E V
Sbjct: 280 EITLSFKTWQRNGLILHTGKSA------DYVNLALKDGAVSLVINLGSGAFEAIVEPVNG 333
Query: 3389 TYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCN--TPLSLAPPYYYGGLRYVNERIS 3446
+ND WH V +TRN ++VD ++ T T T L +Y GG +
Sbjct: 334 KFNDNAWHDVKVTRNLRQVTISVDG-ILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPG 392
Query: 3447 KIFDNFYQPFMGCLKGLLMNGQQV-TRIGNAVNALRCVDNIEDGVYFEASN--------- 3496
N FMGCLK ++ + + I V F+ N
Sbjct: 393 SPVSN---NFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINF 449
Query: 3497 NTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK--------------DYMVL 3542
T Y+ L + SIS + R GL+L HGK D+ +
Sbjct: 450 ETPEAYIS-LPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAV 508
Query: 3543 ELLDSEVVANVENGNGPF--RATYKLSNKHYLCDGNWHKI 3580
ELLD + ++ G+G +AT K +N DG W+ +
Sbjct: 509 ELLDGNLYLLLDMGSGTIKVKATQKKAN-----DGEWYHV 543
Score = 41.9 bits (94), Expect = 0.042
Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 2877 FRTYAPNGLIYLVGEGGY--FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKL 2934
F+T GL+ + +GG F L + DGRV L+ S+ E ++ + + ND WH L
Sbjct: 55 FKTNVSTGLLLYLDDGGVCDFLCLSLVDGRVQLRFSMDCAETAVL--SNKQVNDSSWHFL 112
Query: 2935 DARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMN--FGGNNKGILQVPDRGFDGCMRQ 2992
R + L +D E +S P +D ++ F G ++ DG
Sbjct: 113 MVSRDRLRTVLMLDGE---GQSGELQPQRPYMDVVSDLFLGGVPTDIRPSALTLDGVQAM 169
Query: 2993 ISINGVNLDL 3002
G+ LDL
Sbjct: 170 PGFKGLILDL 179
Score = 41.9 bits (94), Expect = 0.042
Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT-YN 3391
L + F T K G ++ +SA FL + K+ +FN G I T N
Sbjct: 1107 LAVGFSTTVKDG-ILVRIDSAPGLG--DFLQLHIEQGKIGVVFNIGTVDISIKEERTPVN 1163
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNT 3425
D +H V TRNGG+ L VD+ V E T NT
Sbjct: 1164 DGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNT 1197
Score = 41.1 bits (92), Expect = 0.073
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 13/84 (15%)
Query: 2661 TSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPG 2720
TS H+ F+T DGFIL+ +D++ + + GY + V D+G+ G
Sbjct: 880 TSMHLFFQFKTTSPDGFILF---------NSGDGNDFIAVELVKGYIHYVFDLGN----G 926
Query: 2721 QDPARVSIDKMVADNRWYQVIVDR 2744
+ + + D+ + DN+W+ V++ R
Sbjct: 927 PNVIKGNSDRPLNDNQWHNVVITR 950
Score = 40.7 bits (91), Expect = 0.097
Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Query: 3333 LTISFRTFDKQGGVIFY-------AESAHDKNP-VQFLAFFMRDAKLHYMFNCGGETGVI 3384
++ FRT + G ++F ++ KN V F A + D L+ + + G T +
Sbjct: 469 ISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKV 528
Query: 3385 SSTHTY-NDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPYYYGGL 3438
+T ND +W+ V + R+G G ++V+S T+ + L L Y GGL
Sbjct: 529 KATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGL 583
Score = 39.9 bits (89), Expect = 0.17
Identities = 49/190 (25%), Positives = 78/190 (41%), Gaps = 15/190 (7%)
Query: 3009 IGMAYGCQFASLVSFNGTDSYLRFVDVTSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMP 3068
+G+ G +F L N YLR+ D ++ + L+ +FKT GLL +Y+
Sbjct: 22 LGLCLGLEFMGLP--NQWARYLRW-DASTRS-DLSFQFKTNVSTGLL-LYLDDGGVC--- 73
Query: 3069 DSISLSLVNGKLVVVSQREQLDTGL---NTYNDSQWHVLTVTHNTSALKLVVDDFDYFST 3125
D + LSLV+G++ + + +T + NDS WH L V+ + L++D
Sbjct: 74 DFLCLSLVDGRVQLRFSMDCAETAVLSNKQVNDSSWHFLMVSRDRLRTVLMLDGEGQSGE 133
Query: 3126 DTAPPPLHILDGVLFIGGV----QPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLEPFS 3181
P + LF+GGV +P + + + F G I D LL
Sbjct: 134 LQPQRPYMDVVSDLFLGGVPTDIRPSALTLDGVQAMPGFKGLILDLKYGNSEPRLLGSRG 193
Query: 3182 NNSVTFGRCG 3191
G CG
Sbjct: 194 VQMDAEGPCG 203
Score = 39.5 bits (88), Expect = 0.22
Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 13/109 (11%)
Query: 3018 ASLVSFNGTDSYLRFVD---VTSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLS 3074
AS++S++G+ Y++ + + +E ++ +F + + GLL SR D++ L
Sbjct: 681 ASILSYDGS-MYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSA----DTLRLE 735
Query: 3075 LVNG--KLVVVSQR--EQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDD 3119
L G KL+V + E L G ND++WH + V +LKL VDD
Sbjct: 736 LDGGRVKLMVNLGKGPETLYAG-QKLNDNEWHTVRVVRRGKSLKLTVDD 783
Score = 37.1 bits (82), Expect = 1.2
Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 16/150 (10%)
Query: 3035 VTSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVV-----SQREQL 3089
+ S + ++TL FKT + NGL+ T D ++L+L +G + +V E +
Sbjct: 274 IQSSSDEITLSFKTWQRNGLIL------HTGKSADYVNLALKDGAVSLVINLGSGAFEAI 327
Query: 3090 DTGLN-TYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHIL--DGVLFIGGVQP 3146
+N +ND+ WH + VT N + + VD +T +L D ++GG
Sbjct: 328 VEPVNGKFNDNAWHDVKVTRNLRQVTISVDGI-LTTTGYTQEDYTMLGSDDFFYVGGSPS 386
Query: 3147 GYVVSGSLGSKVPFTGCIGDATINGQVLNL 3176
+ GS S F GC+ + + L
Sbjct: 387 TADLPGSPVSN-NFMGCLKEVVYKNNDIRL 415
>AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo 2
protein.
Length = 3014
Score = 74.5 bits (175), Expect = 6e-12
Identities = 54/177 (30%), Positives = 78/177 (44%), Gaps = 34/177 (19%)
Query: 421 TDGLCP----CKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGD-----C 470
T CP C + SC +C+ GY C + C N ++ C + G C
Sbjct: 1877 TSSPCPPNSRCHDAWEDYSC-VCDKGYLGINCVDACHLNPCENMG-ACVRSPGSPQGYVC 1934
Query: 471 TCKSKYSGRTCNQ-----CQAGYYNYPTCKPCNCDTS-GTEPSICDDVSGQCICKAGFGG 524
C + G C C G++ P C PC+C S G +P C+ +GQC
Sbjct: 1935 ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPD-CNKTNGQC-------- 1985
Query: 525 PRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCS-ADGKCNCLTNFGGAQCDQC 580
QC YY ++L ++ C+PC+C P GS S +C A G+C C G QC++C
Sbjct: 1986 ----QCKENYY-KLLAQDT-CLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 74.1 bits (174), Expect = 9e-12
Identities = 51/186 (27%), Positives = 70/186 (37%), Gaps = 25/186 (13%)
Query: 353 DELDVCQPCQCDPHFSTGNCEE--ESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNL 410
D DV PC P C + E C C + +C D + PC N+
Sbjct: 1868 DGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC-------VDACHLNPCE-NM 1919
Query: 411 NGTEGEHCTPTDGLCPCKYNYAGKSCEI-----CEDGYY-SPECKNCECNTVGSVSYVCD 464
+P +C C ++ G CE C G++ +P C C C C+
Sbjct: 1920 GACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPDCN 1979
Query: 465 KLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGG 524
K G C CK Y TC PC+C G+ CD +GQC CK G G
Sbjct: 1980 KTNGQCQCKENYYKLLAQD---------TCLPCDCFPHGSHSRTCDMATGQCACKPGVIG 2030
Query: 525 PRCDQC 530
+C++C
Sbjct: 2031 RQCNRC 2036
Score = 71.3 bits (167), Expect = 6e-11
Identities = 55/191 (28%), Positives = 80/191 (41%), Gaps = 32/191 (16%)
Query: 595 CDVSGSIGST-CDDNGLCHCKSNFDGAKCDTCREQFYNYPACEECNCDP-RGVTASFAGC 652
CDV S+ C N CH ++ C C + + + C+ +P + A
Sbjct: 1870 CDVDDPCTSSPCPPNSRCH--DAWEDYSC-VCDKGYLGINCVDACHLNPCENMGACVRSP 1926
Query: 653 GSVPAGELCQCKDRVQGRICND-----CKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGAC 707
GS P G +C+C G C + C +W NP C C+C ++ + C
Sbjct: 1927 GS-PQGYVCECGPSHYGPYCENKLDLPCPRGWWG----NPV-CGPCHCAVSKGFDP--DC 1978
Query: 708 NTKSGQCVCKQHVGERQCDQCLDGFYRLQTNDVFGCTECDCDIGGSIDNNCDKTTGQCHC 767
N +GQC CK++ +Y+L D C CDC GS CD TGQC C
Sbjct: 1979 NKTNGQCQCKEN------------YYKLLAQDT--CLPCDCFPHGSHSRTCDMATGQCAC 2024
Query: 768 HSRVEGRRCDQ 778
V GR+C++
Sbjct: 2025 KPGVIGRQCNR 2035
Score = 65.3 bits (152), Expect = 4e-09
Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 21/129 (16%)
Query: 1947 CVCRPGVIGEKCDR-----CAPDHWGLNTGLGCTPCNCGIASE-STQCDDDNGQCRCAKG 2000
C C P G C+ C WG C PC+C ++ C+ NGQC+C +
Sbjct: 1934 CECGPSHYGPYCENKLDLPCPRGWWGNPV---CGPCHCAVSKGFDPDCNKTNGQCQCKEN 1990
Query: 2001 VTGKQCDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCN-ATGQCECLPGVIGEKCDRCPER 2059
+ +D C C+C S C+ ATGQC C PGVIG +C+RC
Sbjct: 1991 Y-----------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNP 2039
Query: 2060 WVLIPQEGC 2068
+ + GC
Sbjct: 2040 FAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 29/171 (16%)
Query: 1815 CACPMPYPSNNFALSCDLSENGSLISCNCQPGY-GGARCEYCAAGYYG--------IPED 1865
C C Y N +C L+ ++ +C PG G CE C +YG +P
Sbjct: 1896 CVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCP 1954
Query: 1866 TDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSK 1925
C PC+C+ + DP C+ NG C +C N Y +
Sbjct: 1955 RGWWGNPVCGPCHCAVS-KGFDP-DCNKTNGQC-QCKEN-------------YYKLLAQD 1998
Query: 1926 NCTACICDEFG--MADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGC 1974
C C C G CD TG C C+PGVIG +C+RC + + T LGC
Sbjct: 1999 TCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC-DNPFAEVTTLGC 2048
Score = 62.1 bits (144), Expect = 4e-08
Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 21/191 (10%)
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCR 1950
C+++ G C++ + G C C P YG +K C +G C G C C
Sbjct: 1916 CENM-GACVRSPGSPQGYVCE-CGPSHYGPYCENKLDLPCPRGWWGNPVC----GPCHCA 1969
Query: 1951 PGV-IGEKCDR------CAPDHWGLNTGLGCTPCNC-GIASESTQCDDDNGQCRCAKGVT 2002
C++ C +++ L C PC+C S S CD GQC C GV
Sbjct: 1970 VSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVI 2029
Query: 2003 GKQCDQCAAGFWNYTKDGCD--HCNCNTGYSVGFMCNAT--GQCECLP---GVIGEKCDR 2055
G+QC++C F T GC+ + C + G T GQ +P G +G
Sbjct: 2030 GRQCNRCDNPFAEVTTLGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRH 2089
Query: 2056 CPERWVLIPQE 2066
C +P E
Sbjct: 2090 CSGEKGWLPPE 2100
Score = 61.7 bits (143), Expect = 5e-08
Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 20/143 (13%)
Query: 320 EGGGKCLNCQHNTEGINCNKCRPTYYRPYGKR---------WDELDVCQPCQCDPHFSTG 370
E G C+ + +G C +C P++Y PY + W VC PC C
Sbjct: 1917 ENMGACVRSPGSPQGYVC-ECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFD 1975
Query: 371 -NCEEESGRCECRPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKY 429
+C + +G+C+C+ + Y C PC C +G+ C G C CK
Sbjct: 1976 PDCNKTNGQCQCKENY---------YKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKP 2026
Query: 430 NYAGKSCEICEDGYYSPECKNCE 452
G+ C C++ + CE
Sbjct: 2027 GVIGRQCNRCDNPFAEVTTLGCE 2049
Score = 55.6 bits (128), Expect = 3e-06
Identities = 45/158 (28%), Positives = 61/158 (38%), Gaps = 30/158 (18%)
Query: 1373 CRTGYYGFPNCRPCHCPSTAICDDNGMCI-CPKNVEGENCD----RCKPYTFN---FDVQ 1424
C GY G CH C++ G C+ P + +G C+ PY N
Sbjct: 1898 CDKGYLGINCVDACHLNP---CENMGACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCP 1954
Query: 1425 RG------CDDCNCNPLGVVGNQLQCEADSGKCACRENVRGRVC-DHCVPGHYAFPDCYQ 1477
RG C C+C G C +G+C C+EN + D C+P
Sbjct: 1955 RGWWGNPVCGPCHCAVSK--GFDPDCNKTNGQCQCKENYYKLLAQDTCLP---------- 2002
Query: 1478 CTCNRHGTTYDVCDQNTAQCYCKTNVRGQACDTCKEEY 1515
C C HG+ CD T QC CK V G+ C+ C +
Sbjct: 2003 CDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNPF 2040
Score = 50.0 bits (114), Expect = 2e-04
Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 28/197 (14%)
Query: 548 CNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGS-IGSTCD 606
C+ D TS+ C + +C+ CD+ G C C+ G+ + S
Sbjct: 1870 CDVDDP-CTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGS 1928
Query: 607 DNG-LCHCKSNFDGAKCDT-----CREQFYNYPACEECNCDPRGVTASFAGCGSVPAGEL 660
G +C C + G C+ C ++ P C C+C V+ F + G+
Sbjct: 1929 PQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHC---AVSKGFDPDCNKTNGQ- 1984
Query: 661 CQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHV 720
CQCK+ + D C C+C G+ + C+ +GQC CK V
Sbjct: 1985 CQCKENYYKLLAQDT--------------CLPCDCFPHGSHSR--TCDMATGQCACKPGV 2028
Query: 721 GERQCDQCLDGFYRLQT 737
RQC++C + F + T
Sbjct: 2029 IGRQCNRCDNPFAEVTT 2045
Score = 44.8 bits (101), Expect = 0.006
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 1322 CREAMFSITSEYNSGARPCLCDFMGSTELECNTFGGQCPCKPNVIGRTCSAC 1373
C+E + + ++ PC C GS C+ GQC CKP VIGR C+ C
Sbjct: 1987 CKENYYKLLAQ--DTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRC 2036
Score = 43.6 bits (98), Expect = 0.014
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 14/81 (17%)
Query: 1339 PCLCDFMGSTELECNTFGGQCPCKPN----VIGRTCSACRTGYYGFPNCRPCHCPSTAIC 1394
PC C + +CN GQC CK N + TC C +C P H + C
Sbjct: 1965 PCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPC--------DCFP-HGSHSRTC 2015
Query: 1395 D-DNGMCICPKNVEGENCDRC 1414
D G C C V G C+RC
Sbjct: 2016 DMATGQCACKPGVIGRQCNRC 2036
Score = 34.3 bits (75), Expect = 8.4
Identities = 14/35 (40%), Positives = 23/35 (65%)
Query: 2981 VPDRGFDGCMRQISINGVNLDLSENLESIGMAYGC 3015
V +R F GCMR +S++G N+D++ + + G GC
Sbjct: 1612 VHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGC 1646
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 74.5 bits (175), Expect = 6e-12
Identities = 94/356 (26%), Positives = 125/356 (35%), Gaps = 85/356 (23%)
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFD 399
C P + PY +C P CD G C++ G C+CR +Q C C
Sbjct: 212 CNPGWKGPYCTE----PICLP-GCDEQH--GFCDKP-GECKCRVGWQGRYCDEC----IR 259
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC--EICEDGYYSPECKN-CECNTV 456
YP C TC P C C+ + G C ++ ++ P CKN C
Sbjct: 260 YPGCLHGTCQ---------QPWQ--CNCQEGWGGLFCNQDLNYCTHHKP-CKNGATCTNT 307
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDV--SG 514
G SY C+C+ Y+G TC C P C G+ C D+ S
Sbjct: 308 GQGSYT-------CSCRPGYTGATCE------LGIDECDPSPCKNGGS----CTDLENSY 350
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGG 574
C C GF G C+ LS C C G S S C C + G
Sbjct: 351 SCTCPPGFYGKICE--LSA---------MTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG 399
Query: 575 AQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNG---LCHCKSNFDGAKCDTCREQFYN 631
C++ K C S C S G+ C D G LC C++ F G CD + +
Sbjct: 400 FNCEK------KIDYCSSSPC----SNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCAS 449
Query: 632 YP-----ACEE------CNCDP----RGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
P C + C C P R +A + C P C +R G +C
Sbjct: 450 SPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVC 505
Score = 62.9 bits (146), Expect = 2e-08
Identities = 95/384 (24%), Positives = 140/384 (36%), Gaps = 59/384 (15%)
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDC 470
G E + G KY+Y +C++ YY C C + C + G+
Sbjct: 156 GEEWSQDLHSSGRTDLKYSYRF----VCDEHYYGEGCSVFCRPRDDAFGHFTCGE-RGEK 210
Query: 471 TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQC 530
C + G C + P C P CD + CD G+C C+ G+ G CD+C
Sbjct: 211 VCNPGWKGPYCTE--------PICLP-GCDE---QHGFCDK-PGECKCRVGWQGRYCDEC 257
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNF----GGAQCDQCSPGYYK 586
+ Y + G +Q CNC G C+ D N T+ GA C G Y
Sbjct: 258 IR-YPGCLHGTCQQPWQCNCQ-EGWGGLFCNQD--LNYCTHHKPCKNGATCTNTGQGSY- 312
Query: 587 YPDCLSCNCDVSGSIGSTCDDNGLCHCKSN--FDGAKCDTCREQFYNYPACEECNCDPRG 644
+C+C G G+TC + G+ C + +G C T E Y+ C C P
Sbjct: 313 -----TCSCR-PGYTGATC-ELGIDECDPSPCKNGGSC-TDLENSYS------CTCPP-- 356
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
F G + C G C+D ++ + P G NC S
Sbjct: 357 ---GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR--CPVGYSGFNCEKKIDYCSS 411
Query: 705 GACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTG 763
C + +CV +G+ +C GF +D V C C GG+ + + +
Sbjct: 412 SPC-SNGAKCV---DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS- 466
Query: 764 QCHCHSRVEGRRCDQPI-RAHYFP 786
C C GR C P+ R + P
Sbjct: 467 -CTCPPGYTGRNCSAPVSRCEHAP 489
Score = 56.8 bits (131), Expect = 1e-06
Identities = 82/299 (27%), Positives = 109/299 (36%), Gaps = 51/299 (17%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQ----CDVNTGICLN------- 1783
EC+C ++G C++C L P QCN C+ + C +
Sbjct: 242 ECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 1784 --CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C + G + C GY G AT + I C P P N SC EN SC
Sbjct: 302 ATCTNTGQGSYTCSCRPGYTG-ATC----ELGIDECD-PSPCKNGG-SCTDLENS--YSC 352
Query: 1842 NCQPGYGGARCEY----CAAG-YYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPG 1889
C PG+ G CE CA G + +D G Y C NC I+
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSS 412
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C NG KCV+ C C GF G ++C + D+ + C + GT C
Sbjct: 413 PCS--NG--AKCVDLGDAYLCR-CQAGFSG-----RHCDDNV-DDCASSPC-ANGGT--C 458
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQ-CRCAKGVTGKQC 2006
R GV C C P + G N + C C + +G C CA+G G C
Sbjct: 459 RDGVNDFSC-TCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGYGGPNC 516
Score = 53.6 bits (123), Expect = 1e-05
Identities = 90/319 (28%), Positives = 118/319 (36%), Gaps = 75/319 (23%)
Query: 1762 CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHG--DATVGTPRDC------- 1812
C+P C+ CD G C C G +C+ C+ Y G T P C
Sbjct: 226 CLP-GCDEQHGFCD-KPGEC-KCRVGWQGRYCDECIR-YPGCLHGTCQQPWQCNCQEGWG 281
Query: 1813 -LICACPMPY-----PSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDT 1866
L C + Y P N A +C + GS +C+C+PGY GA CE GI
Sbjct: 282 GLFCNQDLNYCTHHKPCKNGA-TCTNTGQGSY-TCSCRPGYTGATCE------LGI---- 329
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
D C P C ++ GSC + + C C PGFYG
Sbjct: 330 -----DECDPSPC------KNGGSCTDLE-NSYSCT----------CPPGFYGKIC---E 364
Query: 1927 CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASEST 1986
+A C + C G C P G C RC + G N C+ S
Sbjct: 365 LSAMTCAD---GPC-FNGGRCSDSPDG-GYSC-RCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 1987 QCDD--DNGQCRCAKGVTGKQC----DQCAA---GFWNYTKDGCD--HCNCNTGYSVGFM 2035
+C D D CRC G +G+ C D CA+ +DG + C C GY+ G
Sbjct: 419 KCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYT-GRN 477
Query: 2036 CNA-TGQCECLPGVIGEKC 2053
C+A +CE P G C
Sbjct: 478 CSAPVSRCEHAPCHNGATC 496
Score = 52.4 bits (120), Expect = 3e-05
Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 44/296 (14%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP----CNCHNHTTECTYDPEIDEK 309
C+C+ G C++C Q W + +C+ C+ CT+
Sbjct: 243 CKCRVGWQGRYCDECIRYPGCLHGTCQQPW-QCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 310 RLSLDINGRYEGGGKCLNCQHNTEGINC----NKCRPTYYRPYGKRWDELDVCQPCQCDP 365
+ +G C +C+ G C ++C P+ + G D L+ C C P
Sbjct: 302 ATCTNTG---QGSYTC-SCRPGYTGATCELGIDECDPSPCKNGGSCTD-LENSYSCTCPP 356
Query: 366 HFSTGNCEEESGRCECRPEFQPPDCSS---------CAYGYFDYPNC--KPCTCNLNG-T 413
F CE + C P F CS C GY + NC K C+ + +
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGF-NCEKKIDYCSSSPCS 415
Query: 414 EGEHCTPTDG--LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G C LC C+ ++G+ C+ D +C + C G+ + + CT
Sbjct: 416 NGAKCVDLGDAYLCRCQAGFSGRHCDDNVD-----DCASSPCANGGTCRDGVNDFS--CT 468
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC 527
C Y+GR C+ + + P C G +C+ C G+GGP C
Sbjct: 469 CPPGYTGRNCSAPVSRCEHAPCHNGATCHERG-HGYVCE-------CARGYGGPNC 516
Score = 43.2 bits (97), Expect = 0.018
Identities = 50/189 (26%), Positives = 61/189 (32%), Gaps = 28/189 (14%)
Query: 1322 CREAMFSITSEYN-SGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
CR T E P C GS T+LE N++ C C P G+ C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLE-NSYS--CTCPPGFYGKICELSAMTCAD 372
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
P C + D C CP G NC++ Y + G C LG
Sbjct: 373 GPCFNGGRCSDSP--DGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA---KCVDLG--- 424
Query: 1440 NQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
D+ C C+ GR CD V DC C GT D N C C
Sbjct: 425 -------DAYLCRCQAGFSGRHCDDNV------DDCASSPCANGGTCRD--GVNDFSCTC 469
Query: 1500 KTNVRGQAC 1508
G+ C
Sbjct: 470 PPGYTGRNC 478
Score = 42.3 bits (95), Expect = 0.032
Identities = 43/156 (27%), Positives = 56/156 (35%), Gaps = 19/156 (12%)
Query: 1933 DEFGMADCDSTTGTCVCRPGVIGEKCDR--CAP---DHWGLNTGLGCTPCNCGIASESTQ 1987
D FG C G VC PG G C C P + G G C C + +
Sbjct: 197 DAFGHFTCGER-GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG--ECKCRVGWQGRY 253
Query: 1988 CDDDNGQCRCAKGVTGK--QCDQCAAGFWN-YTKDGCDHCNCNTGYSVGFMCNATGQ--- 2041
CD+ C G + QC+ C G+ + ++C + G C TGQ
Sbjct: 254 CDECIRYPGCLHGTCQQPWQCN-CQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSY 312
Query: 2042 -CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTD 2076
C C PG G C+ + P C SCTD
Sbjct: 313 TCSCRPGYTGATCELGIDECDPSP---CKNGGSCTD 345
Score = 42.3 bits (95), Expect = 0.032
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 19/133 (14%)
Query: 1736 CQCPRAYRGLSCEQ---------CAEGHYRLPSGFCVPCQCN-GHSDQ-CDVNTGICLN- 1783
C+CP Y G +CE+ C+ G + G C+C G S + CD N C +
Sbjct: 391 CRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASS 450
Query: 1784 -CADNTIGDHCEFCMSGYHGDATVG-TPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
CA+ G C ++ + G T R+C + + +C E G C
Sbjct: 451 PCAN---GGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATC--HERGHGYVC 505
Query: 1842 NCQPGYGGARCEY 1854
C GYGG C++
Sbjct: 506 ECARGYGGPNCQF 518
Score = 41.5 bits (93), Expect = 0.056
Identities = 47/176 (26%), Positives = 61/176 (34%), Gaps = 31/176 (17%)
Query: 1381 PNCRPCHCPSTAICDDNGMCICPKNVEGENCDRC--KPYTFNFDVQRGCDDCNCNPLGVV 1438
P C P CD G C C +G CD C P + Q+ CNC G
Sbjct: 224 PICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPW-QCNCQE-GWG 281
Query: 1439 GNQLQCEADSGKC----------ACRENVRGRVCDHCVPGH------YAFPDCYQCTCNR 1482
G L C D C C +G C PG+ +C C
Sbjct: 282 G--LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKN 339
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACD----TCKE-EYFN--LQDDNPDGCTKCFC 1531
G+ D+ +N+ C C G+ C+ TC + FN D+PDG C C
Sbjct: 340 GGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRC 393
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 74.5 bits (175), Expect = 6e-12
Identities = 96/363 (26%), Positives = 127/363 (34%), Gaps = 86/363 (23%)
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFD 399
C P + PY +C P CD G C++ G C+CR +Q C C
Sbjct: 212 CNPGWKGPYCTE----PICLP-GCDEQH--GFCDKP-GECKCRVGWQGRYCDEC----IR 259
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC--EICEDGYYSPECKN-CECNTV 456
YP C TC P C C+ + G C ++ ++ P CKN C
Sbjct: 260 YPGCLHGTCQ---------QPWQ--CNCQEGWGGLFCNQDLNYCTHHKP-CKNGATCTNT 307
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDV--SG 514
G SY C+C+ Y+G TC C P C G+ C D+ S
Sbjct: 308 GQGSYT-------CSCRPGYTGATCE------LGIDECDPSPCKNGGS----CTDLENSY 350
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGG 574
C C GF G C+ LS C C G S S C C + G
Sbjct: 351 SCTCPPGFYGKICE--LSA---------MTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG 399
Query: 575 AQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNG---LCHCKSNFDGAKCDTCREQFYN 631
C++ K C S C S G+ C D G LC C++ F G CD + +
Sbjct: 400 FNCEK------KIDYCSSSPC----SNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCAS 449
Query: 632 YP-----ACEE------CNCDP----RGVTASFAGCGSVPAGELCQCKDRVQGRICNDCK 676
P C + C C P R +A + C P C R G +C +C
Sbjct: 450 SPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHQRGHGYVC-ECA 508
Query: 677 PLY 679
Y
Sbjct: 509 RSY 511
Score = 62.9 bits (146), Expect = 2e-08
Identities = 95/384 (24%), Positives = 140/384 (36%), Gaps = 59/384 (15%)
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDC 470
G E + G KY+Y +C++ YY C C + C + G+
Sbjct: 156 GEEWSQDLHSSGRTDLKYSYRF----VCDEHYYGEGCSVFCRPRDDAFGHFTCGE-RGEK 210
Query: 471 TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQC 530
C + G C + P C P CD + CD G+C C+ G+ G CD+C
Sbjct: 211 VCNPGWKGPYCTE--------PICLP-GCDE---QHGFCDK-PGECKCRVGWQGRYCDEC 257
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNF----GGAQCDQCSPGYYK 586
+ Y + G +Q CNC G C+ D N T+ GA C G Y
Sbjct: 258 IR-YPGCLHGTCQQPWQCNCQ-EGWGGLFCNQD--LNYCTHHKPCKNGATCTNTGQGSY- 312
Query: 587 YPDCLSCNCDVSGSIGSTCDDNGLCHCKSN--FDGAKCDTCREQFYNYPACEECNCDPRG 644
+C+C G G+TC + G+ C + +G C T E Y+ C C P
Sbjct: 313 -----TCSCR-PGYTGATC-ELGIDECDPSPCKNGGSC-TDLENSYS------CTCPP-- 356
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
F G + C G C+D ++ + P G NC S
Sbjct: 357 ---GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR--CPVGYSGFNCEKKIDYCSS 411
Query: 705 GACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTG 763
C + +CV +G+ +C GF +D V C C GG+ + + +
Sbjct: 412 SPC-SNGAKCV---DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS- 466
Query: 764 QCHCHSRVEGRRCDQPI-RAHYFP 786
C C GR C P+ R + P
Sbjct: 467 -CTCPPGYTGRNCSAPVSRCEHAP 489
Score = 58.4 bits (135), Expect = 5e-07
Identities = 66/258 (25%), Positives = 94/258 (36%), Gaps = 43/258 (16%)
Query: 328 CQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCE--EESGRCECRPEF 385
C + +G CRP Y + +D C P C + G+C E S C C P F
Sbjct: 304 CTNTGQGSYTCSCRPGYTGATCELG--IDECDPSPCK---NGGSCTDLENSYSCTCPPGF 358
Query: 386 QPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYS 445
C A D P C+ + +G + C C Y+G +CE D S
Sbjct: 359 YGKICELSAMTCADGPCFNGGRCS-DSPDGGYS------CRCPVGYSGFNCEKKIDYCSS 411
Query: 446 PECKN-CECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGT 504
C N +C +G +Y+C C++ +SGR C+ N C C GT
Sbjct: 412 SPCSNGAKCVDLGD-AYLC-------RCQAGFSGRHCDD------NVDDCASSPCANGGT 457
Query: 505 EPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADG 564
+D S C C G+ G C +S + PC+ G+T
Sbjct: 458 CRDGVNDFS--CTCPPGYTGRNCSAPVS---------RCEHAPCH---NGATCHQRGHGY 503
Query: 565 KCNCLTNFGGAQCDQCSP 582
C C ++GG C P
Sbjct: 504 VCECARSYGGPNCQFLLP 521
Score = 53.6 bits (123), Expect = 1e-05
Identities = 90/319 (28%), Positives = 118/319 (36%), Gaps = 75/319 (23%)
Query: 1762 CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHG--DATVGTPRDC------- 1812
C+P C+ CD G C C G +C+ C+ Y G T P C
Sbjct: 226 CLP-GCDEQHGFCD-KPGEC-KCRVGWQGRYCDECIR-YPGCLHGTCQQPWQCNCQEGWG 281
Query: 1813 -LICACPMPY-----PSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDT 1866
L C + Y P N A +C + GS +C+C+PGY GA CE GI
Sbjct: 282 GLFCNQDLNYCTHHKPCKNGA-TCTNTGQGSY-TCSCRPGYTGATCE------LGI---- 329
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
D C P C ++ GSC + + C C PGFYG
Sbjct: 330 -----DECDPSPC------KNGGSCTDLE-NSYSCT----------CPPGFYGKIC---E 364
Query: 1927 CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASEST 1986
+A C + C G C P G C RC + G N C+ S
Sbjct: 365 LSAMTCAD---GPC-FNGGRCSDSPDG-GYSC-RCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 1987 QCDD--DNGQCRCAKGVTGKQC----DQCAA---GFWNYTKDGCD--HCNCNTGYSVGFM 2035
+C D D CRC G +G+ C D CA+ +DG + C C GY+ G
Sbjct: 419 KCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYT-GRN 477
Query: 2036 CNA-TGQCECLPGVIGEKC 2053
C+A +CE P G C
Sbjct: 478 CSAPVSRCEHAPCHNGATC 496
Score = 53.6 bits (123), Expect = 1e-05
Identities = 81/299 (27%), Positives = 107/299 (35%), Gaps = 51/299 (17%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQ----CDVNTGICLN------- 1783
EC+C ++G C++C L P QCN C+ + C +
Sbjct: 242 ECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 1784 --CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C + G + C GY G AT + I C P P N SC EN SC
Sbjct: 302 ATCTNTGQGSYTCSCRPGYTG-ATC----ELGIDECD-PSPCKNGG-SCTDLENS--YSC 352
Query: 1842 NCQPGYGGARCEY----CAAG-YYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPG 1889
C PG+ G CE CA G + +D G Y C NC I+
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSS 412
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C NG KCV+ C C GF G ++C + D+ + C + GT C
Sbjct: 413 PCS--NG--AKCVDLGDAYLCR-CQAGFSG-----RHCDDNV-DDCASSPC-ANGGT--C 458
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQ-CRCAKGVTGKQC 2006
R GV C C P + G N + C C +G C CA+ G C
Sbjct: 459 RDGVNDFSC-TCPPGYTGRNCSAPVSRCEHAPCHNGATCHQRGHGYVCECARSYGGPNC 516
Score = 50.0 bits (114), Expect = 2e-04
Identities = 66/296 (22%), Positives = 106/296 (35%), Gaps = 44/296 (14%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP----CNCHNHTTECTYDPEIDEK 309
C+C+ G C++C Q W + +C+ C+ CT+
Sbjct: 243 CKCRVGWQGRYCDECIRYPGCLHGTCQQPW-QCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 310 RLSLDINGRYEGGGKCLNCQHNTEGINC----NKCRPTYYRPYGKRWDELDVCQPCQCDP 365
+ +G C +C+ G C ++C P+ + G D L+ C C P
Sbjct: 302 ATCTNTG---QGSYTC-SCRPGYTGATCELGIDECDPSPCKNGGSCTD-LENSYSCTCPP 356
Query: 366 HFSTGNCEEESGRCECRPEFQPPDCSS---------CAYGYFDYPNC--KPCTCNLNG-T 413
F CE + C P F CS C GY + NC K C+ + +
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGF-NCEKKIDYCSSSPCS 415
Query: 414 EGEHCTPTDG--LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G C LC C+ ++G+ C+ D +C + C G+ + + CT
Sbjct: 416 NGAKCVDLGDAYLCRCQAGFSGRHCDDNVD-----DCASSPCANGGTCRDGVNDFS--CT 468
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC 527
C Y+GR C+ + + P C G +C+ C +GGP C
Sbjct: 469 CPPGYTGRNCSAPVSRCEHAPCHNGATCHQRG-HGYVCE-------CARSYGGPNC 516
Score = 43.2 bits (97), Expect = 0.018
Identities = 50/189 (26%), Positives = 61/189 (32%), Gaps = 28/189 (14%)
Query: 1322 CREAMFSITSEYN-SGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
CR T E P C GS T+LE N++ C C P G+ C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLE-NSYS--CTCPPGFYGKICELSAMTCAD 372
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
P C + D C CP G NC++ Y + G C LG
Sbjct: 373 GPCFNGGRCSDSP--DGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA---KCVDLG--- 424
Query: 1440 NQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
D+ C C+ GR CD V DC C GT D N C C
Sbjct: 425 -------DAYLCRCQAGFSGRHCDDNV------DDCASSPCANGGTCRD--GVNDFSCTC 469
Query: 1500 KTNVRGQAC 1508
G+ C
Sbjct: 470 PPGYTGRNC 478
Score = 42.3 bits (95), Expect = 0.032
Identities = 43/156 (27%), Positives = 56/156 (35%), Gaps = 19/156 (12%)
Query: 1933 DEFGMADCDSTTGTCVCRPGVIGEKCDR--CAP---DHWGLNTGLGCTPCNCGIASESTQ 1987
D FG C G VC PG G C C P + G G C C + +
Sbjct: 197 DAFGHFTCGER-GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG--ECKCRVGWQGRY 253
Query: 1988 CDDDNGQCRCAKGVTGK--QCDQCAAGFWN-YTKDGCDHCNCNTGYSVGFMCNATGQ--- 2041
CD+ C G + QC+ C G+ + ++C + G C TGQ
Sbjct: 254 CDECIRYPGCLHGTCQQPWQCN-CQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSY 312
Query: 2042 -CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTD 2076
C C PG G C+ + P C SCTD
Sbjct: 313 TCSCRPGYTGATCELGIDECDPSP---CKNGGSCTD 345
Score = 41.5 bits (93), Expect = 0.056
Identities = 47/176 (26%), Positives = 61/176 (34%), Gaps = 31/176 (17%)
Query: 1381 PNCRPCHCPSTAICDDNGMCICPKNVEGENCDRC--KPYTFNFDVQRGCDDCNCNPLGVV 1438
P C P CD G C C +G CD C P + Q+ CNC G
Sbjct: 224 PICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPW-QCNCQE-GWG 281
Query: 1439 GNQLQCEADSGKC----------ACRENVRGRVCDHCVPGH------YAFPDCYQCTCNR 1482
G L C D C C +G C PG+ +C C
Sbjct: 282 G--LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKN 339
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACD----TCKE-EYFN--LQDDNPDGCTKCFC 1531
G+ D+ +N+ C C G+ C+ TC + FN D+PDG C C
Sbjct: 340 GGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRC 393
Score = 39.1 bits (87), Expect = 0.30
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 19/133 (14%)
Query: 1736 CQCPRAYRGLSCEQ---------CAEGHYRLPSGFCVPCQCN-GHSDQ-CDVNTGICLN- 1783
C+CP Y G +CE+ C+ G + G C+C G S + CD N C +
Sbjct: 391 CRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASS 450
Query: 1784 -CADNTIGDHCEFCMSGYHGDATVG-TPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
CA+ G C ++ + G T R+C + + +C +G + C
Sbjct: 451 PCAN---GGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHQRGHGYV--C 505
Query: 1842 NCQPGYGGARCEY 1854
C YGG C++
Sbjct: 506 ECARSYGGPNCQF 518
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 74.5 bits (175), Expect = 6e-12
Identities = 94/356 (26%), Positives = 125/356 (35%), Gaps = 85/356 (23%)
Query: 340 CRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRPEFQPPDCSSCAYGYFD 399
C P + PY +C P CD G C++ G C+CR +Q C C
Sbjct: 212 CNPGWKGPYCTE----PICLP-GCDEQH--GFCDKP-GECKCRVGWQGRYCDEC----IR 259
Query: 400 YPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSC--EICEDGYYSPECKN-CECNTV 456
YP C TC P C C+ + G C ++ ++ P CKN C
Sbjct: 260 YPGCLHGTCQ---------QPWQ--CNCQEGWGGLFCNQDLNYCTHHKP-CKNGATCTNT 307
Query: 457 GSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDV--SG 514
G SY C+C+ Y+G TC C P C G+ C D+ S
Sbjct: 308 GQGSYT-------CSCRPGYTGATCE------LGIDECDPSPCKNGGS----CTDLENSY 350
Query: 515 QCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGG 574
C C GF G C+ LS C C G S S C C + G
Sbjct: 351 SCTCPPGFYGKICE--LSA---------MTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG 399
Query: 575 AQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNG---LCHCKSNFDGAKCDTCREQFYN 631
C++ K C S C S G+ C D G LC C++ F G CD + +
Sbjct: 400 FNCEK------KIDYCSSSPC----SNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCAS 449
Query: 632 YP-----ACEE------CNCDP----RGVTASFAGCGSVPAGELCQCKDRVQGRIC 672
P C + C C P R +A + C P C +R G +C
Sbjct: 450 SPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVC 505
Score = 62.9 bits (146), Expect = 2e-08
Identities = 95/384 (24%), Positives = 140/384 (36%), Gaps = 59/384 (15%)
Query: 412 GTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN-CECNTVGSVSYVCDKLTGDC 470
G E + G KY+Y +C++ YY C C + C + G+
Sbjct: 156 GEEWSQDLHSSGRTDLKYSYRF----VCDEHYYGEGCSVFCRPRDDAFGHFTCGE-RGEK 210
Query: 471 TCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRCDQC 530
C + G C + P C P CD + CD G+C C+ G+ G CD+C
Sbjct: 211 VCNPGWKGPYCTE--------PICLP-GCDE---QHGFCDK-PGECKCRVGWQGRYCDEC 257
Query: 531 LSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNF----GGAQCDQCSPGYYK 586
+ Y + G +Q CNC G C+ D N T+ GA C G Y
Sbjct: 258 IR-YPGCLHGTCQQPWQCNCQ-EGWGGLFCNQD--LNYCTHHKPCKNGATCTNTGQGSY- 312
Query: 587 YPDCLSCNCDVSGSIGSTCDDNGLCHCKSN--FDGAKCDTCREQFYNYPACEECNCDPRG 644
+C+C G G+TC + G+ C + +G C T E Y+ C C P
Sbjct: 313 -----TCSCR-PGYTGATC-ELGIDECDPSPCKNGGSC-TDLENSYS------CTCPP-- 356
Query: 645 VTASFAGCGSVPAGELCQCKDRVQGRICNDCKPLYWNLQEYNPFGCEQCNCNLAGTLNSL 704
F G + C G C+D ++ + P G NC S
Sbjct: 357 ---GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR--CPVGYSGFNCEKKIDYCSS 411
Query: 705 GACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTND-VFGCTECDCDIGGSIDNNCDKTTG 763
C + +CV +G+ +C GF +D V C C GG+ + + +
Sbjct: 412 SPC-SNGAKCV---DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS- 466
Query: 764 QCHCHSRVEGRRCDQPI-RAHYFP 786
C C GR C P+ R + P
Sbjct: 467 -CTCPPGYTGRNCSAPVSRCEHAP 489
Score = 56.8 bits (131), Expect = 1e-06
Identities = 82/299 (27%), Positives = 109/299 (36%), Gaps = 51/299 (17%)
Query: 1735 ECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQ----CDVNTGICLN------- 1783
EC+C ++G C++C L P QCN C+ + C +
Sbjct: 242 ECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 1784 --CADNTIGDHCEFCMSGYHGDATVGTPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
C + G + C GY G AT + I C P P N SC EN SC
Sbjct: 302 ATCTNTGQGSYTCSCRPGYTG-ATC----ELGIDECD-PSPCKNGG-SCTDLENS--YSC 352
Query: 1842 NCQPGYGGARCEY----CAAG-YYGIPEDTDLHTGDYCKPC-------NCSGNINPQDPG 1889
C PG+ G CE CA G + +D G Y C NC I+
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSS 412
Query: 1890 SCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVC 1949
C NG KCV+ C C GF G ++C + D+ + C + GT C
Sbjct: 413 PCS--NG--AKCVDLGDAYLCR-CQAGFSG-----RHCDDNV-DDCASSPC-ANGGT--C 458
Query: 1950 RPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDD-DNGQ-CRCAKGVTGKQC 2006
R GV C C P + G N + C C + +G C CA+G G C
Sbjct: 459 RDGVNDFSC-TCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGYGGPNC 516
Score = 53.6 bits (123), Expect = 1e-05
Identities = 90/319 (28%), Positives = 118/319 (36%), Gaps = 75/319 (23%)
Query: 1762 CVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHG--DATVGTPRDC------- 1812
C+P C+ CD G C C G +C+ C+ Y G T P C
Sbjct: 226 CLP-GCDEQHGFCD-KPGEC-KCRVGWQGRYCDECIR-YPGCLHGTCQQPWQCNCQEGWG 281
Query: 1813 -LICACPMPY-----PSNNFALSCDLSENGSLISCNCQPGYGGARCEYCAAGYYGIPEDT 1866
L C + Y P N A +C + GS +C+C+PGY GA CE GI
Sbjct: 282 GLFCNQDLNYCTHHKPCKNGA-TCTNTGQGSY-TCSCRPGYTGATCE------LGI---- 329
Query: 1867 DLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKN 1926
D C P C ++ GSC + + C C PGFYG
Sbjct: 330 -----DECDPSPC------KNGGSCTDLE-NSYSCT----------CPPGFYGKIC---E 364
Query: 1927 CTACICDEFGMADCDSTTGTCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASEST 1986
+A C + C G C P G C RC + G N C+ S
Sbjct: 365 LSAMTCAD---GPC-FNGGRCSDSPDG-GYSC-RCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 1987 QCDD--DNGQCRCAKGVTGKQC----DQCAA---GFWNYTKDGCD--HCNCNTGYSVGFM 2035
+C D D CRC G +G+ C D CA+ +DG + C C GY+ G
Sbjct: 419 KCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYT-GRN 477
Query: 2036 CNA-TGQCECLPGVIGEKC 2053
C+A +CE P G C
Sbjct: 478 CSAPVSRCEHAPCHNGATC 496
Score = 52.4 bits (120), Expect = 3e-05
Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 44/296 (14%)
Query: 254 CRCQHNTCGPQCNKCCSGFEQKKWRISQNWDRFSCEP----CNCHNHTTECTYDPEIDEK 309
C+C+ G C++C Q W + +C+ C+ CT+
Sbjct: 243 CKCRVGWQGRYCDECIRYPGCLHGTCQQPW-QCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 310 RLSLDINGRYEGGGKCLNCQHNTEGINC----NKCRPTYYRPYGKRWDELDVCQPCQCDP 365
+ +G C +C+ G C ++C P+ + G D L+ C C P
Sbjct: 302 ATCTNTG---QGSYTC-SCRPGYTGATCELGIDECDPSPCKNGGSCTD-LENSYSCTCPP 356
Query: 366 HFSTGNCEEESGRCECRPEFQPPDCSS---------CAYGYFDYPNC--KPCTCNLNG-T 413
F CE + C P F CS C GY + NC K C+ + +
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGF-NCEKKIDYCSSSPCS 415
Query: 414 EGEHCTPTDG--LCPCKYNYAGKSCEICEDGYYSPECKNCECNTVGSVSYVCDKLTGDCT 471
G C LC C+ ++G+ C+ D +C + C G+ + + CT
Sbjct: 416 NGAKCVDLGDAYLCRCQAGFSGRHCDDNVD-----DCASSPCANGGTCRDGVNDFS--CT 468
Query: 472 CKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTEPSICDDVSGQCICKAGFGGPRC 527
C Y+GR C+ + + P C G +C+ C G+GGP C
Sbjct: 469 CPPGYTGRNCSAPVSRCEHAPCHNGATCHERG-HGYVCE-------CARGYGGPNC 516
Score = 43.2 bits (97), Expect = 0.018
Identities = 50/189 (26%), Positives = 61/189 (32%), Gaps = 28/189 (14%)
Query: 1322 CREAMFSITSEYN-SGARPCLCDFMGS-TELECNTFGGQCPCKPNVIGRTCSACRTGYYG 1379
CR T E P C GS T+LE N++ C C P G+ C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLE-NSYS--CTCPPGFYGKICELSAMTCAD 372
Query: 1380 FPNCRPCHCPSTAICDDNGMCICPKNVEGENCDRCKPYTFNFDVQRGCDDCNCNPLGVVG 1439
P C + D C CP G NC++ Y + G C LG
Sbjct: 373 GPCFNGGRCSDSP--DGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA---KCVDLG--- 424
Query: 1440 NQLQCEADSGKCACRENVRGRVCDHCVPGHYAFPDCYQCTCNRHGTTYDVCDQNTAQCYC 1499
D+ C C+ GR CD V DC C GT D N C C
Sbjct: 425 -------DAYLCRCQAGFSGRHCDDNV------DDCASSPCANGGTCRD--GVNDFSCTC 469
Query: 1500 KTNVRGQAC 1508
G+ C
Sbjct: 470 PPGYTGRNC 478
Score = 42.3 bits (95), Expect = 0.032
Identities = 43/156 (27%), Positives = 56/156 (35%), Gaps = 19/156 (12%)
Query: 1933 DEFGMADCDSTTGTCVCRPGVIGEKCDR--CAP---DHWGLNTGLGCTPCNCGIASESTQ 1987
D FG C G VC PG G C C P + G G C C + +
Sbjct: 197 DAFGHFTCGER-GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPG--ECKCRVGWQGRY 253
Query: 1988 CDDDNGQCRCAKGVTGK--QCDQCAAGFWN-YTKDGCDHCNCNTGYSVGFMCNATGQ--- 2041
CD+ C G + QC+ C G+ + ++C + G C TGQ
Sbjct: 254 CDECIRYPGCLHGTCQQPWQCN-CQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSY 312
Query: 2042 -CECLPGVIGEKCDRCPERWVLIPQEGCLECDSCTD 2076
C C PG G C+ + P C SCTD
Sbjct: 313 TCSCRPGYTGATCELGIDECDPSP---CKNGGSCTD 345
Score = 42.3 bits (95), Expect = 0.032
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 19/133 (14%)
Query: 1736 CQCPRAYRGLSCEQ---------CAEGHYRLPSGFCVPCQCN-GHSDQ-CDVNTGICLN- 1783
C+CP Y G +CE+ C+ G + G C+C G S + CD N C +
Sbjct: 391 CRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASS 450
Query: 1784 -CADNTIGDHCEFCMSGYHGDATVG-TPRDCLICACPMPYPSNNFALSCDLSENGSLISC 1841
CA+ G C ++ + G T R+C + + +C E G C
Sbjct: 451 PCAN---GGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATC--HERGHGYVC 505
Query: 1842 NCQPGYGGARCEY 1854
C GYGG C++
Sbjct: 506 ECARGYGGPNCQF 518
Score = 41.5 bits (93), Expect = 0.056
Identities = 47/176 (26%), Positives = 61/176 (34%), Gaps = 31/176 (17%)
Query: 1381 PNCRPCHCPSTAICDDNGMCICPKNVEGENCDRC--KPYTFNFDVQRGCDDCNCNPLGVV 1438
P C P CD G C C +G CD C P + Q+ CNC G
Sbjct: 224 PICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPW-QCNCQE-GWG 281
Query: 1439 GNQLQCEADSGKC----------ACRENVRGRVCDHCVPGH------YAFPDCYQCTCNR 1482
G L C D C C +G C PG+ +C C
Sbjct: 282 G--LFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKN 339
Query: 1483 HGTTYDVCDQNTAQCYCKTNVRGQACD----TCKE-EYFN--LQDDNPDGCTKCFC 1531
G+ D+ +N+ C C G+ C+ TC + FN D+PDG C C
Sbjct: 340 GGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRC 393
>AB018286-1|BAA34463.2| 1205|Homo sapiens KIAA0743 protein protein.
Length = 1205
Score = 74.5 bits (175), Expect = 6e-12
Identities = 75/344 (21%), Positives = 157/344 (45%), Gaps = 37/344 (10%)
Query: 2870 SNQVLLFFRTYAPNGLIYLVGEGGYFFSLLMQDGRVYLQVSLGN-TEDLIIVGTTRAYND 2928
S+++ L F+T+ NGLI G+ + +L ++DG V L ++LG+ + I+ +ND
Sbjct: 51 SDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFND 110
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGILQVP----DR 2984
WH + R L + +++VD + + D + G + +P
Sbjct: 111 NAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN 170
Query: 2985 GFDGCMRQI--SINGVNLDLSE-------NLESIG-MAYGCQ-FASL--VSFNGTDSYLR 3031
F GC++++ N + L+LS ++ G + + C+ A+L ++F ++Y+
Sbjct: 171 NFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINFETPEAYIS 230
Query: 3032 FVD-VTSENPQLTLKFKTAKPNGL-LFVY-------VSRTQTAIMPDSISLSLVNGKLVV 3082
T ++ F+T +PNGL LF + +R+Q D ++ L++G L +
Sbjct: 231 LPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYL 290
Query: 3083 V----SQREQLDTGLNTYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGV 3138
+ S ++ ND +W+ + + + + + V+ T + + L+G
Sbjct: 291 LLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGD 350
Query: 3139 LFIGGV---QPGYVVSGSLGSKV---PFTGCIGDATINGQVLNL 3176
+++GG+ + G ++ L + + + GCI D I+G+ N+
Sbjct: 351 MYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNI 394
Score = 58.8 bits (136), Expect = 3e-07
Identities = 94/401 (23%), Positives = 175/401 (43%), Gaps = 59/401 (14%)
Query: 2660 STSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSS-E 2718
S+S ++ F+T +++G IL+ G KS DY+ + +++G +V+++G + E
Sbjct: 49 SSSDEITLSFKTWQRNGLILHTG----------KSADYVNLALKDGAVSLVINLGSGAFE 98
Query: 2719 PGQDPARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIF 2778
+P + DN W+ V V R R+V +S+ L T T +++E +T+
Sbjct: 99 AIVEPVNGKFN----DNAWHDVKVTRNLRQVTISVDGIL---TTTGYTQE-----DYTML 146
Query: 2779 NLDKEKSKLYVGGVPSDAKLQGISFPA-FEGQIEELMIGDTPVGL----WNFVSANKLKG 2833
D YVGG PS A L G F G ++E++ + + L ++ K+K
Sbjct: 147 GSD---DFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKI 203
Query: 2834 ARQRDKLISSQSGPQEYRFDG-RGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYLV-GE 2891
+ + + F+ Y ++ + T + + FRT PNGLI G+
Sbjct: 204 YGEVVFKCENVATLDPINFETPEAYISLPK--WNTKRMGSISFDFRTTEPNGLILFTHGK 261
Query: 2892 GGY-------------FFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARR 2938
FF++ + DG +YL + +G+ + + T + NDG+W+ +D +R
Sbjct: 262 PQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGT-IKVKATQKKANDGEWYHVDIQR 320
Query: 2939 FLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGG--NNKGILQVPDR--------GFDG 2988
+++V++ ++ S + M GG N+ L +P G+ G
Sbjct: 321 DGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVG 380
Query: 2989 CMRQISINGVNLDLSENLESIGMAYGCQFASLVSFNGTDSY 3029
C+R + I+G + ++ + E A S +S DSY
Sbjct: 381 CIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSY 421
Score = 54.8 bits (126), Expect = 6e-06
Identities = 74/305 (24%), Positives = 133/305 (43%), Gaps = 30/305 (9%)
Query: 2723 PARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDK 2782
P + + + DN W+ V V R G+ +KL++ + + GT + L H+ +
Sbjct: 533 PETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGT--MVGDHTRLEFHNIETGIMT 590
Query: 2783 EKSKLYVGGVPSDAKLQGISFPAFEGQIEELMI-GDTPVGLWNFVSANKLKGARQRDKLI 2841
EK Y+ VPS +F G ++ LM G + L + + + R L
Sbjct: 591 EKR--YISVVPS----------SFIGHLQSLMFNGLLYIDLCKNGDIDYCE-LKARFGLR 637
Query: 2842 SSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLI-YLVGEGGYFFSLLM 2900
+ + P ++ Y ++A T S + F+T +P+G I + G+G F ++ +
Sbjct: 638 NIIADPVTFKTKS-SYLSLATLQAYT--SMHLFFQFKTTSPDGFILFNSGDGNDFIAVEL 694
Query: 2901 QDGRVYLQVSLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKC-SLTVDNEVLKAESNSP 2959
G ++ LGN ++I + R ND +WH + R + SL VD +V+ N
Sbjct: 695 VKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVING- 753
Query: 2960 SADIPSLDTMNFGGNNKGILQ-----VPDR-GFDGCMRQISINGVNLDL-SENLESIG-M 3011
+ ++ + G +G+ V R GF GC+ + +NG DL ++ L G +
Sbjct: 754 AKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQI 813
Query: 3012 AYGCQ 3016
GC+
Sbjct: 814 KRGCE 818
Score = 51.6 bits (118), Expect = 5e-05
Identities = 66/297 (22%), Positives = 117/297 (39%), Gaps = 19/297 (6%)
Query: 3376 NCGGETG--VISSTHTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPY 3433
NC G + + ND +WHTV + R G KL VD ++ T V +T L
Sbjct: 526 NCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEF--HN 583
Query: 3434 YYGGLRYVNERISKIFDNFYQPFMGCLKGLLMNGQ---QVTRIGNA-VNALRCVDNIEDG 3489
G+ IS + + F+G L+ L+ NG + + G+ L+ + +
Sbjct: 584 IETGIMTEKRYISVVPSS----FIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNI 639
Query: 3490 VYFEASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGK-KDYMVLELLDSE 3548
+ + T S+YL L + + + + + + G +L G D++ +EL+
Sbjct: 640 IADPVTFKTKSSYLS-LATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKGY 698
Query: 3549 VVANVENGNGPFRATYKLSNKHYLCDGNWHK-IHXXXXXXXXXXXXDGHFSKPGIGAYTS 3607
+ + GNGP K ++ L D WH + D I +
Sbjct: 699 IHYVFDLGNGP--NVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKN 756
Query: 3608 TDTHSALYIGGHERPIHK--VRGVHSRRGFTGCVRNIVVGETPVKVPNSAVGRGAHV 3662
D LY+ G + ++ + V SR GF GC+ ++ + + N A+ R +
Sbjct: 757 LDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQI 813
Score = 50.4 bits (115), Expect = 1e-04
Identities = 64/270 (23%), Positives = 110/270 (40%), Gaps = 28/270 (10%)
Query: 2927 NDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDTMNFGGNNKGILQVPDRGF 2986
ND +WH + R LTVD++V + + + K + V F
Sbjct: 543 NDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSF 602
Query: 2987 DGCMRQISING-VNLDLSENLE----SIGMAYGCQ--FASLVSFNGTDSYLRFVDVTS-E 3038
G ++ + NG + +DL +N + + +G + A V+F SYL + +
Sbjct: 603 IGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYT 662
Query: 3039 NPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVVSQREQLDTGLNT--- 3095
+ L +FKT P+G + + D I++ LV G + V L G N
Sbjct: 663 SMHLFFQFKTTSPDGFILF-----NSGDGNDFIAVELVKGYIHYVF---DLGNGPNVIKG 714
Query: 3096 -----YNDSQWHVLTVTH-NTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIGGVQPGYV 3149
ND+QWH + +T N++ L VD L L G L++ G+ G
Sbjct: 715 NSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLD-LKGDLYMAGLAQGMY 773
Query: 3150 --VSGSLGSKVPFTGCIGDATINGQVLNLL 3177
+ + S+ F GC+ +NG++ +L+
Sbjct: 774 SNLPKLVASRDGFQGCLASVDLNGRLPDLI 803
Score = 49.2 bits (112), Expect = 3e-04
Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 6/148 (4%)
Query: 3513 DEVSISMEVRPRNTTGLLLSVHGKKDYMVLELLDSEVVANVENGNGPFRATYKLSNKHYL 3572
DE+++S + RN GL+L DY+ L L D V + G+G F A + N +
Sbjct: 52 DEITLSFKTWQRN--GLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKF- 108
Query: 3573 CDGNWHKIHXXXXXXXXXXXXDGHFSKPGIGA--YTSTDTHSALYIGGHERPIHKVRGVH 3630
D WH + DG + G YT + Y+GG + G
Sbjct: 109 NDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTA-DLPGSP 167
Query: 3631 SRRGFTGCVRNIVVGETPVKVPNSAVGR 3658
F GC++ +V +++ S + R
Sbjct: 168 VSNNFMGCLKEVVYKNNDIRLELSRLAR 195
Score = 48.4 bits (110), Expect = 5e-04
Identities = 67/280 (23%), Positives = 109/280 (38%), Gaps = 47/280 (16%)
Query: 3332 DLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGG---ETGVISSTH 3388
++T+SF+T+ + G ++ +SA ++ ++D + + N G E V
Sbjct: 53 EITLSFKTWQRNGLILHTGKSA------DYVNLALKDGAVSLVINLGSGAFEAIVEPVNG 106
Query: 3389 TYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCN--TPLSLAPPYYYGGLRYVNERIS 3446
+ND WH V +TRN ++VD ++ T T T L +Y GG +
Sbjct: 107 KFNDNAWHDVKVTRNLRQVTISVDG-ILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPG 165
Query: 3447 KIFDNFYQPFMGCLKGLLMNGQQV-TRIGNAVNALRCVDNIEDGVYFEASN--------- 3496
N FMGCLK ++ + + I V F+ N
Sbjct: 166 SPVSN---NFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINF 222
Query: 3497 NTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKK--------------DYMVL 3542
T Y+ L + SIS + R GL+L HGK D+ +
Sbjct: 223 ETPEAYIS-LPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAV 281
Query: 3543 ELLDSEVVANVENGNGPF--RATYKLSNKHYLCDGNWHKI 3580
ELLD + ++ G+G +AT K +N DG W+ +
Sbjct: 282 ELLDGNLYLLLDMGSGTIKVKATQKKAN-----DGEWYHV 316
Score = 41.1 bits (92), Expect = 0.073
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 13/84 (15%)
Query: 2661 TSTHVSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPG 2720
TS H+ F+T DGFIL+ +D++ + + GY + V D+G+ G
Sbjct: 662 TSMHLFFQFKTTSPDGFILF---------NSGDGNDFIAVELVKGYIHYVFDLGN----G 708
Query: 2721 QDPARVSIDKMVADNRWYQVIVDR 2744
+ + + D+ + DN+W+ V++ R
Sbjct: 709 PNVIKGNSDRPLNDNQWHNVVITR 732
Score = 40.7 bits (91), Expect = 0.097
Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Query: 3333 LTISFRTFDKQGGVIFY-------AESAHDKNP-VQFLAFFMRDAKLHYMFNCGGETGVI 3384
++ FRT + G ++F ++ KN V F A + D L+ + + G T +
Sbjct: 242 ISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKV 301
Query: 3385 SSTHTY-NDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPYYYGGL 3438
+T ND +W+ V + R+G G ++V+S T+ + L L Y GGL
Sbjct: 302 KATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGL 356
Score = 39.1 bits (87), Expect = 0.30
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHT-YN 3391
L + F T K G ++ +SA FL + K+ +FN G I T N
Sbjct: 889 LAVGFSTTVKDG-ILVRIDSAPGLG--DFLQLHIEQGKIGVVFNIGTVDISIKEERTPVN 945
Query: 3392 DIDWHTVTLTRNGGHGKLAVDSEMVGE 3418
D +H V TRNGG+ L VD+ V E
Sbjct: 946 DGKYHVVRFTRNGGNATLQVDNWPVNE 972
Score = 37.1 bits (82), Expect = 1.2
Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 16/150 (10%)
Query: 3035 VTSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVVV-----SQREQL 3089
+ S + ++TL FKT + NGL+ T D ++L+L +G + +V E +
Sbjct: 47 IQSSSDEITLSFKTWQRNGLIL------HTGKSADYVNLALKDGAVSLVINLGSGAFEAI 100
Query: 3090 DTGLN-TYNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHIL--DGVLFIGGVQP 3146
+N +ND+ WH + VT N + + VD +T +L D ++GG
Sbjct: 101 VEPVNGKFNDNAWHDVKVTRNLRQVTISVDGI-LTTTGYTQEDYTMLGSDDFFYVGGSPS 159
Query: 3147 GYVVSGSLGSKVPFTGCIGDATINGQVLNL 3176
+ GS S F GC+ + + L
Sbjct: 160 TADLPGSPVSN-NFMGCLKEVVYKNNDIRL 188
Score = 34.7 bits (76), Expect = 6.4
Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 20/117 (17%)
Query: 3018 ASLVSFNGTDSYLRFVD---VTSENPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLS 3074
AS++S++G+ Y++ + + +E ++ +F + + GLL SR D++ L
Sbjct: 454 ASILSYDGS-MYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSA----DTLRLE 508
Query: 3075 LVNGKLVVVSQREQLDTGLNT------------YNDSQWHVLTVTHNTSALKLVVDD 3119
L G++ ++ + + N+ ND++WH + V +LKL VDD
Sbjct: 509 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDD 565
Score = 34.7 bits (76), Expect = 6.4
Identities = 35/153 (22%), Positives = 70/153 (45%), Gaps = 13/153 (8%)
Query: 2869 QSNQVLLFFRTYAPNGLIYLVGEG---GYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRA 2925
+S+++ + F T +G++ + G F L ++ G++ + ++G T D+ I
Sbjct: 885 RSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIG-TVDISIKEERTP 943
Query: 2926 YNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLDT---MNFGGNNKGIL--- 2979
NDGK+H + R +L VDN + E + +T + GG +KG L
Sbjct: 944 VNDGKYHVVRFTRNGGNATLQVDNWPVN-EHYPTGRQLTIFNTQAQIAIGGKDKGRLFQG 1002
Query: 2980 QVPDRGFDG--CMRQISINGVNLDLSENLESIG 3010
Q+ +DG + + N N+ ++ ++ +G
Sbjct: 1003 QLSGLYYDGLKVLNMAAENNPNIKINGSVRLVG 1035
>BC131820-1|AAI31821.1| 1976|Homo sapiens FRAS1 protein protein.
Length = 1976
Score = 74.1 bits (174), Expect = 9e-12
Identities = 102/447 (22%), Positives = 154/447 (34%), Gaps = 65/447 (14%)
Query: 317 GRYEGGGKCLNCQHN----TEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
G Y+ G CL CQ T G+ C+ C+P +G+ + C S C
Sbjct: 457 GFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQC---VPTCGDGFYQDRHSCAVC 513
Query: 373 EEESGRC---------ECRPE---FQPPDC-SSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
E C CR + C SSC G+++ + TC+ + C
Sbjct: 514 HESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYN----RQGTCSACDQSCDSCG 569
Query: 420 PTDGLC-PCKYN---YAGKSCEICEDGYYSP---ECKNCECNTVGSVSYVCDKLTGDCTC 472
P+ C C + GK C GYY+ CK C + T
Sbjct: 570 PSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPP 629
Query: 473 KSKYSGRTCNQCQAGYY-NYPTCKPCNCD---TSGTEPSIC-------DDVSGQCICKAG 521
K+ G +C G+Y ++ CK C+ G PS C + + + + G
Sbjct: 630 KALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVG 689
Query: 522 FGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
C QC + +Y++ G C G + +C+ G + L + G QC
Sbjct: 690 IPSGECLAQCRAHFYLESTGICEACHQSCFRCAGKSPHNCTDCGPSHVLLD--GQCLSQC 747
Query: 581 SPGYY-KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CR-EQFYN------ 631
GY+ + C C+ G D C+ + C T CR EQF N
Sbjct: 748 PDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCA 807
Query: 632 --YPACEECNCDPRGVTASFAGCGS---VPAGELC--QCKD--RVQGRICNDCKPLYWNL 682
+ C+ C D + C + + G+ C C + C C
Sbjct: 808 DCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTC 867
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGACNT 709
Q PF C C+ NL L+ G C+T
Sbjct: 868 QGRGPFSCSSCDTNL--VLSHTGTCST 892
Score = 56.4 bits (130), Expect = 2e-06
Identities = 116/473 (24%), Positives = 168/473 (35%), Gaps = 84/473 (17%)
Query: 229 GRCM-CNGHADTCEPADPAGNLNILVCRCQHNTCGPQC-NKCCSGFEQK---KWRISQNW 283
G C C+ D+C P+ P L C + +C ++C G+ + ++ N
Sbjct: 556 GTCSACDQSCDSCGPSSP----RCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHN- 610
Query: 284 DRFSCEPCN--CHNHTTECTYDPEIDEKR-LSLDINGRYEGGGKCLNCQHNT---EGINC 337
SC C+ +H T C+ + + L G Y G C C + G
Sbjct: 611 ---SCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAP 667
Query: 338 NKCRPTYYRPYGKRWDEL-DVCQP-----CQCDPHF---STGNCE---EESGRCECRPEF 385
+ C G + ++L DV P QC HF STG CE + RC +
Sbjct: 668 SHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLESTGICEACHQSCFRCAGKSPH 727
Query: 386 QPPDC------------SSCAYGYFD--------YPNCKPCTCNLNG---TEGEHCTPTD 422
DC S C GYF +P C+ C L + H + T+
Sbjct: 728 NCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISLTN 787
Query: 423 GLC--PCKYNYAGKSCEICEDGYYSPECKNC--ECNTVGSVSYVCDKLTGDCTCKSKYSG 478
G C C+ C D ++ C++C + + GS+ C G
Sbjct: 788 GNCRTSCREEQFLNLVGYCADCHHL--CQHCAADLHNTGSICLRCQN------AHYLLLG 839
Query: 479 RTC-NQCQAGYY-NYPTCKPCN--CDT-SGTEPSICDDVSGQCICKAGFGGPRCDQCLSG 533
C C +GYY CK C+ C T G P C + G C G
Sbjct: 840 DHCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLS--HTGTCSTTCFPG 897
Query: 534 YYMQVLGRERQCVPCN--CDPTGSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYKYPDCL 591
+Y L C PCN C S + SC++ N + FG Q + C+P YY
Sbjct: 898 HY---LDDNHVCQPCNTHCGSCDSQA-SCTSCRDPNKVLLFGECQYESCAPQYYLDFSTN 953
Query: 592 SC-NCDVSGSIGSTCDDNGLCHCKSNF---DGAKCDTCREQFY-NYPACEECN 639
+C CD S S S C + DGA + C FY + C+ C+
Sbjct: 954 TCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQDSGLCKNCD 1006
Score = 54.8 bits (126), Expect = 6e-06
Identities = 87/378 (23%), Positives = 122/378 (32%), Gaps = 55/378 (14%)
Query: 1736 CQCP-RAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTI---G 1790
C+ P R CE C +G Y G C C+ D C ++ CL C + T+ G
Sbjct: 531 CRDPLHVLRDGGCESSCGKGFYNR-QGTC--SACDQSCDSCGPSSPRCLTCTEKTVLHDG 587
Query: 1791 DHCEFCMSGYHGDAT--------------VGTPRDCLICACPMPYPSNNFALSCD---LS 1833
C GY+ DAT TP C C+ P + C S
Sbjct: 588 KCMSECPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYS 647
Query: 1834 ENGSLISC--NCQPGYGGA--RCEYCAAGYYGIPEDTDLHTGDYCKPC--NCSGNINPQD 1887
++G +C +C G A C C G+ + G C C + +
Sbjct: 648 DHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLES 707
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF--GMADCDSTTG 1945
G C++ + C +C + C C P + C + D + C
Sbjct: 708 TGICEACHQSCFRCAGKSP-HNCTDCGP---SHVLLDGQCLSQCPDGYFHQEGSCTECHP 763
Query: 1946 TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQ 2005
TC G + C C P H L G NC + Q + G C +
Sbjct: 764 TCRQCHGPLESDCISCYP-HISLTNG------NCRTSCREEQFLNLVGYCADCHHL---- 812
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEK--CDRCPERWVLI 2063
C CAA N T C C +G C +C G E+ C +C
Sbjct: 813 CQHCAADLHN-TGSICLRCQNAHYLLLGDHCVP----DCPSGYYAERGACKKCHSSCRTC 867
Query: 2064 PQEGCLECDSCTDALIFS 2081
G C SC L+ S
Sbjct: 868 QGRGPFSCSSCDTNLVLS 885
Score = 50.4 bits (115), Expect = 1e-04
Identities = 83/350 (23%), Positives = 127/350 (36%), Gaps = 69/350 (19%)
Query: 273 EQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDE---KRLSLDINGRYEGGGKCLNCQ 329
E K+ + W+ C+ C C C Y+P L+L++ G+ C +C
Sbjct: 364 EVKRIPEGEKWEDGPCKVCECRGAQVTC-YEPSCPPCPVGTLALEVKGQC-----CPDCT 417
Query: 330 HNTEGINCNK-CRPTYYRPYGKRWDELDVCQ-PCQ------CDPHFSTGNCEEESGRCEC 381
++C+ C P D D+CQ P + C G + S C
Sbjct: 418 ----SVHCHPDCLTCSQSP-----DHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLAC 468
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
+P+ CS+C G C C L G+ C PT C + SC +C +
Sbjct: 469 QPQ-----CSTCTSGL----ECSSCQPPLLMRHGQ-CVPT---CGDGFYQDRHSCAVCHE 515
Query: 442 ---GYYSPECKNC-ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP-TCKP 496
G + P K+C C V D C+S C G+YN TC
Sbjct: 516 SCAGCWGPTEKHCLACRDPLHV-------LRDGGCESS--------CGKGFYNRQGTCSA 560
Query: 497 CN--CDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPT 553
C+ CD+ G C + + + G +C +C GYY GR + C +
Sbjct: 561 CDQSCDSCGPSSPRCLTCTEKTVLHDG----KCMSECPGGYYADATGRCKVCHNSCASCS 616
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYK-YPDCLSCNCDVSGSIG 602
G T + C+A L G +C G+Y + C +C+ +G
Sbjct: 617 GPTPSHCTACSPPKALRQ--GHCLPRCGEGFYSDHGVCKACHSSCLACMG 664
Score = 48.0 bits (109), Expect = 6e-04
Identities = 78/319 (24%), Positives = 107/319 (33%), Gaps = 63/319 (19%)
Query: 1734 EECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADN--TIGD 1791
+ C G C +C HY L CVP +G+ + G C C + T
Sbjct: 814 QHCAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYYAE----RGACKKCHSSCRTCQG 869
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPY--------PSNNFALSCDLSENGSLISCNC 1843
F S + + C P Y P N SCD S SC
Sbjct: 870 RGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCD--SQASCTSCR- 926
Query: 1844 QPG----YGGARCEYCAAGYYGIPEDTDLHTGDYCKPCN--CSGNINPQDPGSCDSINGD 1897
P +G + E CA YY D T CK C+ CS P + D
Sbjct: 927 DPNKVLLFGECQYESCAPQYY-----LDFSTNT-CKECDWSCSACSGP--------LKTD 972
Query: 1898 CLKCVNNTA---GAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCVCRPGVI 1954
CL+C++ GA C FY D+ KNC + G +C G + ++
Sbjct: 973 CLQCMDGYVLQDGACVEQCLSSFYQDSGLCKNCDSYCLQCQGPHECTRCKGPFL----LL 1028
Query: 1955 GEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
+C C ++ + CT C G QC + +C C GF
Sbjct: 1029 EAQCVQECGKGYFADHAKHKCTACPQG----CLQCSHRD------------RCHLCDHGF 1072
Query: 2014 WNYTKDGCDHCNCNTGYSV 2032
+ K G NC G+SV
Sbjct: 1073 --FLKSGLCVYNCVPGFSV 1089
Score = 43.6 bits (98), Expect = 0.014
Identities = 105/465 (22%), Positives = 153/465 (32%), Gaps = 62/465 (13%)
Query: 231 CMCNGHADTC--EPADPAGNLNILVCRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDR 285
C CN C +P P + + +C P C K CS +E ++ ++W
Sbjct: 116 CSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCS-YEGHVFQDGEDWRL 174
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
C C C N +C + + + D G C C +C+ Y
Sbjct: 175 SRCAKCLCRNGVAQC-FTAQCQPLFCNQDETVVRVPGKCCPQCSAR----SCSAAGQVY- 228
Query: 346 RPYGKRWDELDVCQPCQCDPHFSTGNCEEES------GRCECRPEFQPPDCSSCA--YGY 397
+G++W E + C C CD C +++ G+ + R C C G
Sbjct: 229 -EHGEQWSE-NACTTCICDR--GEVRCHKQACLPLRCGKGQSRARRHGQCCEECVSPAGS 284
Query: 398 FDYPNCKPCTCNL-NGTEGEHCTPTDGLCPCKYNYAGK-SCEICE-----DGYYSPEC-- 448
Y + G+ E C G C+ K C E DG PEC
Sbjct: 285 CSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECIS 344
Query: 449 KNCECNTVGSVSYVCDKLTGDCTCK--SKYSGRTCNQCQ---AGYYNY-PTCKPCNCDTS 502
+N C + ++ + K+ C C+ A Y P+C PC T
Sbjct: 345 RNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEPSCPPCPVGTL 404
Query: 503 GTE--PSICDD-VSGQC--ICKAGFGGP-RCDQC-------LSGYYMQVLG---RERQCV 546
E C D S C C P CD C +G+ + G + +
Sbjct: 405 ALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSL 464
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQC-DQCSPGYYK-YPDCLSCNCDVSGSIGST 604
C P ST TS C QC C G+Y+ C C+ +G G T
Sbjct: 465 CLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPT 524
Query: 605 CDDNGLCHCKSNF--DGAKCDTCREQFYN-YPACEEC--NCDPRG 644
C + DG +C + FYN C C +CD G
Sbjct: 525 EKHCLACRDPLHVLRDGGCESSCGKGFYNRQGTCSACDQSCDSCG 569
Score = 38.7 bits (86), Expect = 0.39
Identities = 123/568 (21%), Positives = 192/568 (33%), Gaps = 92/568 (16%)
Query: 253 VCRCQHNT--CGPQ-CNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
VC C H C PQ C G ++ + I + SC P C C+Y+ + +
Sbjct: 115 VCSCNHGEVRCTPQPCPPLSCGHQELAF-IPEG----SCCPV-CVGLGKPCSYEGHVFQD 168
Query: 310 RLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST 369
+ R KCL C++ +C+P + DE V P +C P S
Sbjct: 169 ----GEDWRLSRCAKCL-CRNGVAQCFTAQCQPLFCNQ-----DETVVRVPGKCCPQCSA 218
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDY----PNCKPCTC-------NLNGTEGEHC 418
+C E ++ C++C + C P C +G E C
Sbjct: 219 RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCEEC 278
Query: 419 TPTDGLCP----CKYN---YAGKSCE--ICEDGY---YSPECKNCECNTVGSVSYVCDKL 466
G C +Y + G +CE +C+ G + EC EC + ++ K
Sbjct: 279 VSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKC 338
Query: 467 TGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE----P-SICDDVSGQCICKAG 521
+C ++ Y C + G + G + P +C+ Q C
Sbjct: 339 CPECISRNGY----CVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYE- 393
Query: 522 FGGPRCDQCLSG-YYMQVLGR-ERQCVPCNCDPTGST-STSCSADGKCNCLTNF--GGAQ 576
P C C G ++V G+ C +C P T S S C T G
Sbjct: 394 ---PSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWC 450
Query: 577 CDQCSPGYYKYPD-CLSCNCDVSG-SIGSTCDDNGLCHCKSNFDGAKC-DTCREQFY-NY 632
C G+Y+ CL+C S + G C C +C TC + FY +
Sbjct: 451 VHSCGLGFYQAGSLCLACQPQCSTCTSGLECSS---CQPPLLMRHGQCVPTCGDGFYQDR 507
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----QGRICNDCKPLYWNLQEYNPF 688
+C C+ S AGC C+D + G + C ++N Q
Sbjct: 508 HSCAVCH-------ESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQG---- 556
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQC-DQCLDGFYRLQTNDVFGCTECD 747
C C+ + +S G + + C K + + +C +C G+Y T C
Sbjct: 557 TCSACD----QSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHNSC 612
Query: 748 CDIGGSIDNNC-----DKTTGQCHCHSR 770
G ++C K Q HC R
Sbjct: 613 ASCSGPTPSHCTACSPPKALRQGHCLPR 640
Score = 37.9 bits (84), Expect = 0.68
Identities = 80/348 (22%), Positives = 110/348 (31%), Gaps = 39/348 (11%)
Query: 1749 QCAEGHYRLPS-GFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVG 1807
+C +G R G C +C + C + G+ + G CEFCM HG T
Sbjct: 260 RCGKGQSRARRHGQCCE-ECVSPAGSCSYD-GVVRYQDEMWKGSACEFCMCD-HGQVTCQ 316
Query: 1808 TPRDCLI-CA------------CPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
T + CA CP N + C E G +S N E
Sbjct: 317 TGECAKVECARDEELIHLDGKCCPECISRNGY---CVYEETGEFMSSNASEVKRIPEGEK 373
Query: 1855 CAAGYYGIPEDTDLHTGDY---CKPC---NCSGNINPQDPGSCDSIN--GDCLKCVNNTA 1906
G + E Y C PC + + Q C S++ DCL C + +
Sbjct: 374 WEDGPCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTC--SQS 431
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV--CRPGVIGEKCDRCAPD 1964
C+LC + C G S C C G +C C P
Sbjct: 432 PDHCDLCQDP---TKLLQNGWCVHSCG-LGFYQAGSLCLACQPQCSTCTSGLECSSCQPP 487
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
+ G C G + C + C G T K C C GC+
Sbjct: 488 LL-MRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCES- 545
Query: 2025 NCNTG-YSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
+C G Y+ C+A Q G +C C E+ VL + EC
Sbjct: 546 SCGKGFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSEC 593
>AJ512501-1|CAD54734.1| 4007|Homo sapiens extracellular matrix
protein protein.
Length = 4007
Score = 74.1 bits (174), Expect = 9e-12
Identities = 102/447 (22%), Positives = 154/447 (34%), Gaps = 65/447 (14%)
Query: 317 GRYEGGGKCLNCQHN----TEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNC 372
G Y+ G CL CQ T G+ C+ C+P +G+ + C S C
Sbjct: 457 GFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQC---VPTCGDGFYQDRHSCAVC 513
Query: 373 EEESGRC---------ECRPE---FQPPDC-SSCAYGYFDYPNCKPCTCNLNGTEGEHCT 419
E C CR + C SSC G+++ + TC+ + C
Sbjct: 514 HESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYN----RQGTCSACDQSCDSCG 569
Query: 420 PTDGLC-PCKYN---YAGKSCEICEDGYYSP---ECKNCECNTVGSVSYVCDKLTGDCTC 472
P+ C C + GK C GYY+ CK C + T
Sbjct: 570 PSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPP 629
Query: 473 KSKYSGRTCNQCQAGYY-NYPTCKPCNCD---TSGTEPSIC-------DDVSGQCICKAG 521
K+ G +C G+Y ++ CK C+ G PS C + + + + G
Sbjct: 630 KALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSGVG 689
Query: 522 FGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPTGSTSTSCSADGKCNCLTNFGGAQCDQC 580
C QC + +Y++ G C G + +C+ G + L + G QC
Sbjct: 690 IPSGECLAQCRAHFYLESTGLCEACHQSCFRCAGKSPHNCTDCGPSHVLLD--GQCLSQC 747
Query: 581 SPGYY-KYPDCLSCNCDVSGSIGSTCDDNGLCHCKSNFDGAKCDT-CR-EQFYN------ 631
GY+ + C C+ G D C+ + C T CR EQF N
Sbjct: 748 PDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCA 807
Query: 632 --YPACEECNCDPRGVTASFAGCGS---VPAGELC--QCKD--RVQGRICNDCKPLYWNL 682
+ C+ C D + C + + G+ C C + C C
Sbjct: 808 DCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTC 867
Query: 683 QEYNPFGCEQCNCNLAGTLNSLGACNT 709
Q PF C C+ NL L+ G C+T
Sbjct: 868 QGRGPFSCSSCDTNL--VLSHTGTCST 892
Score = 56.4 bits (130), Expect = 2e-06
Identities = 81/324 (25%), Positives = 113/324 (34%), Gaps = 48/324 (14%)
Query: 337 CNKCRPTYYRPYGKRWDELDVCQPC------QCDPHFSTGNCEEESGRCECRPEFQPPDC 390
C C + +R GK C P QC G +E EC P C
Sbjct: 711 CEACHQSCFRCAGKSPHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPT-----C 765
Query: 391 SSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICEDGYYSPECKN 450
C +G + +C C +++ T G +C + C+ C D ++ C++
Sbjct: 766 RQC-HGPLE-SDCISCYPHISLTNG-NCRTS-----CREEQFLNLVGYCADCHHL--CQH 815
Query: 451 C--ECNTVGSVSYVCDKLTGDCTCKSKYSGRTC-NQCQAGYY-NYPTCKPCN--CDT-SG 503
C + + GS+ C G C C +GYY CK C+ C T G
Sbjct: 816 CAADLHNTGSICLRCQN------AHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQG 869
Query: 504 TEPSICDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCN--CDPTGSTSTSCS 561
P C + G C G+Y L C PCN C S + SC+
Sbjct: 870 RGPFSCSSCDTNLVLS--HTGTCSTTCFPGHY---LDDNHVCQPCNTHCGSCDSQA-SCT 923
Query: 562 ADGKCNCLTNFGGAQCDQCSPGYYKYPDCLSC-NCDVSGSIGSTCDDNGLCHCKSNF--- 617
+ N + FG Q + C+P YY +C CD S S S C +
Sbjct: 924 SCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQ 983
Query: 618 DGAKCDTCREQFYNYPACEECNCD 641
DGA + C FY C CD
Sbjct: 984 DGACVEQCLSSFYQDSGL--CKCD 1005
Score = 54.4 bits (125), Expect = 7e-06
Identities = 87/378 (23%), Positives = 122/378 (32%), Gaps = 55/378 (14%)
Query: 1736 CQCP-RAYRGLSCEQ-CAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADNTI---G 1790
C+ P R CE C +G Y G C C+ D C ++ CL C + T+ G
Sbjct: 531 CRDPLHVLRDGGCESSCGKGFYNR-QGTC--SACDQSCDSCGPSSPRCLTCTEKTVLHDG 587
Query: 1791 DHCEFCMSGYHGDAT--------------VGTPRDCLICACPMPYPSNNFALSCD---LS 1833
C GY+ DAT TP C C+ P + C S
Sbjct: 588 KCMSECPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYS 647
Query: 1834 ENGSLISC--NCQPGYGGA--RCEYCAAGYYGIPEDTDLHTGDYCKPC--NCSGNINPQD 1887
++G +C +C G A C C G+ + G C C + +
Sbjct: 648 DHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSGVGIPSGECLAQCRAHFYLES 707
Query: 1888 PGSCDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEF--GMADCDSTTG 1945
G C++ + C +C + C C P + C + D + C
Sbjct: 708 TGLCEACHQSCFRCAGKSP-HNCTDCGP---SHVLLDGQCLSQCPDGYFHQEGSCTECHP 763
Query: 1946 TCVCRPGVIGEKCDRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQ 2005
TC G + C C P H L G NC + Q + G C +
Sbjct: 764 TCRQCHGPLESDCISCYP-HISLTNG------NCRTSCREEQFLNLVGYCADCHHL---- 812
Query: 2006 CDQCAAGFWNYTKDGCDHCNCNTGYSVGFMCNATGQCECLPGVIGEK--CDRCPERWVLI 2063
C CAA N T C C +G C +C G E+ C +C
Sbjct: 813 CQHCAADLHN-TGSICLRCQNAHYLLLGDHCVP----DCPSGYYAERGACKKCHSSCRTC 867
Query: 2064 PQEGCLECDSCTDALIFS 2081
G C SC L+ S
Sbjct: 868 QGRGPFSCSSCDTNLVLS 885
Score = 50.4 bits (115), Expect = 1e-04
Identities = 83/350 (23%), Positives = 127/350 (36%), Gaps = 69/350 (19%)
Query: 273 EQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDE---KRLSLDINGRYEGGGKCLNCQ 329
E K+ + W+ C+ C C C Y+P L+L++ G+ C +C
Sbjct: 364 EVKRIPEGEKWEDGPCKVCECRGAQVTC-YEPSCPPCPVGTLALEVKGQC-----CPDCT 417
Query: 330 HNTEGINCNK-CRPTYYRPYGKRWDELDVCQ-PCQ------CDPHFSTGNCEEESGRCEC 381
++C+ C P D D+CQ P + C G + S C
Sbjct: 418 ----SVHCHPDCLTCSQSP-----DHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLAC 468
Query: 382 RPEFQPPDCSSCAYGYFDYPNCKPCTCNLNGTEGEHCTPTDGLCPCKYNYAGKSCEICED 441
+P+ CS+C G C C L G+ C PT C + SC +C +
Sbjct: 469 QPQ-----CSTCTSGL----ECSSCQPPLLMRHGQ-CVPT---CGDGFYQDRHSCAVCHE 515
Query: 442 ---GYYSPECKNC-ECNTVGSVSYVCDKLTGDCTCKSKYSGRTCNQCQAGYYNYP-TCKP 496
G + P K+C C V D C+S C G+YN TC
Sbjct: 516 SCAGCWGPTEKHCLACRDPLHV-------LRDGGCESS--------CGKGFYNRQGTCSA 560
Query: 497 CN--CDTSGTEPSICDDVSGQCICKAGFGGPRC-DQCLSGYYMQVLGRERQCVPCNCDPT 553
C+ CD+ G C + + + G +C +C GYY GR + C +
Sbjct: 561 CDQSCDSCGPSSPRCLTCTEKTVLHDG----KCMSECPGGYYADATGRCKVCHNSCASCS 616
Query: 554 GSTSTSCSADGKCNCLTNFGGAQCDQCSPGYYK-YPDCLSCNCDVSGSIG 602
G T + C+A L G +C G+Y + C +C+ +G
Sbjct: 617 GPTPSHCTACSPPKALRQ--GHCLPRCGEGFYSDHGVCKACHSSCLACMG 664
Score = 43.6 bits (98), Expect = 0.014
Identities = 105/465 (22%), Positives = 153/465 (32%), Gaps = 62/465 (13%)
Query: 231 CMCNGHADTC--EPADPAGNLNILVCRCQHNTCGPQC---NKCCSGFEQKKWRISQNWDR 285
C CN C +P P + + +C P C K CS +E ++ ++W
Sbjct: 116 CSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCS-YEGHVFQDGEDWRL 174
Query: 286 FSCEPCNCHNHTTECTYDPEIDEKRLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYY 345
C C C N +C + + + D G C C +C+ Y
Sbjct: 175 SRCAKCLCRNGVAQC-FTAQCQPLFCNQDETVVRVPGKCCPQCSAR----SCSAAGQVY- 228
Query: 346 RPYGKRWDELDVCQPCQCDPHFSTGNCEEES------GRCECRPEFQPPDCSSCA--YGY 397
+G++W E + C C CD C +++ G+ + R C C G
Sbjct: 229 -EHGEQWSE-NACTTCICDR--GEVRCHKQACLPLRCGKGQSRARRHGQCCEECVSPAGS 284
Query: 398 FDYPNCKPCTCNL-NGTEGEHCTPTDGLCPCKYNYAGK-SCEICE-----DGYYSPEC-- 448
Y + G+ E C G C+ K C E DG PEC
Sbjct: 285 CSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECIS 344
Query: 449 KNCECNTVGSVSYVCDKLTGDCTCK--SKYSGRTCNQCQ---AGYYNY-PTCKPCNCDTS 502
+N C + ++ + K+ C C+ A Y P+C PC T
Sbjct: 345 RNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEPSCPPCPVGTL 404
Query: 503 GTE--PSICDD-VSGQC--ICKAGFGGP-RCDQC-------LSGYYMQVLG---RERQCV 546
E C D S C C P CD C +G+ + G + +
Sbjct: 405 ALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSL 464
Query: 547 PCNCDPTGSTSTSCSADGKCNCLTNFGGAQC-DQCSPGYYK-YPDCLSCNCDVSGSIGST 604
C P ST TS C QC C G+Y+ C C+ +G G T
Sbjct: 465 CLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPT 524
Query: 605 CDDNGLCHCKSNF--DGAKCDTCREQFYN-YPACEEC--NCDPRG 644
C + DG +C + FYN C C +CD G
Sbjct: 525 EKHCLACRDPLHVLRDGGCESSCGKGFYNRQGTCSACDQSCDSCG 569
Score = 41.9 bits (94), Expect = 0.042
Identities = 108/485 (22%), Positives = 161/485 (33%), Gaps = 88/485 (18%)
Query: 324 KCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECRP 383
+CL C T ++ KC P G D C+ C +G C
Sbjct: 574 RCLTCTEKTV-LHDGKCMSEC--PGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPK 630
Query: 384 EFQPPDC-SSCAYGYF-DYPNCKPC--TC-NLNGTEGEHCT----PTDGLCPCKYNY--- 431
+ C C G++ D+ CK C +C G HCT P +GL + +
Sbjct: 631 ALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSGVGI 690
Query: 432 -AGKSCEICEDGYYSPECKNCE-CNTVGSVSYVCDKLTGDCT-CKSKY---SGRTCNQCQ 485
+G+ C +Y CE C+ S K +CT C + G+ +QC
Sbjct: 691 PSGECLAQCRAHFYLESTGLCEACHQ--SCFRCAGKSPHNCTDCGPSHVLLDGQCLSQCP 748
Query: 486 AGYYN--------YPTCKPC--------------------NCDTSGTEPSI--------- 508
GY++ +PTC+ C NC TS E
Sbjct: 749 DGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCAD 808
Query: 509 CDDVSGQCICKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNCDPTG--STSTSCS-ADGK 565
C + C G C +C + +Y+ +LG CVP +C P+G + +C
Sbjct: 809 CHHLCQHCAADLHNTGSICLRCQNAHYL-LLGDH--CVP-DC-PSGYYAERGACKKCHSS 863
Query: 566 CNCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDDNGLC-----HCKSNFDGA 620
C G C C + C + G DDN +C HC S A
Sbjct: 864 CRTCQGRGPFSCSSCDTNLVLSH---TGTCSTTCFPGHYLDDNHVCQPCNTHCGSCDSQA 920
Query: 621 KCDTCRE--QFYNYPACEECNCDPRGVTASFAGCGSVPAGELCQCKDRVQGRICNDCKPL 678
C +CR+ + + C+ +C P+ + + E G + DC
Sbjct: 921 SCTSCRDPNKVLLFGECQYESCAPQ----YYLDFSTNTCKECDWSCSACSGPLKTDCLQC 976
Query: 679 YWNLQEYNPFGCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQCDQCLDGFYRLQTN 738
+ EQC L+ G C S C Q G +C +C F L+
Sbjct: 977 MDGYVLQDGACVEQC---LSSFYQDSGLCKCDS---YCLQCQGPHECTRCKGPFLLLEAQ 1030
Query: 739 DVFGC 743
V C
Sbjct: 1031 CVQEC 1035
Score = 41.9 bits (94), Expect = 0.042
Identities = 78/319 (24%), Positives = 108/319 (33%), Gaps = 64/319 (20%)
Query: 1734 EECQCPRAYRGLSCEQCAEGHYRLPSGFCVPCQCNGHSDQCDVNTGICLNCADN--TIGD 1791
+ C G C +C HY L CVP +G+ G C C + T
Sbjct: 814 QHCAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYY----AERGACKKCHSSCRTCQG 869
Query: 1792 HCEFCMSGYHGDATVGTPRDCLICACPMPY--------PSNNFALSCDLSENGSLISC-- 1841
F S + + C P Y P N SCD S SC
Sbjct: 870 RGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCD--SQASCTSCRD 927
Query: 1842 -NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPC--NCSGNINPQDPGSCDSINGDC 1898
N +G + E CA YY D T + CK C +CS P + DC
Sbjct: 928 PNKVLLFGECQYESCAPQYY-----LDFST-NTCKECDWSCSACSGP--------LKTDC 973
Query: 1899 LKCVNNTA---GAACNLCAPGFYGDAIFSKNCTACI-CDEFGMADCDSTTGTCVCRPGVI 1954
L+C++ GA C FY D+ K + C+ C G +C G + ++
Sbjct: 974 LQCMDGYVLQDGACVEQCLSSFYQDSGLCKCDSYCLQCQ--GPHECTRCKGPFL----LL 1027
Query: 1955 GEKC-DRCAPDHWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGF 2013
+C C ++ + CT C G QC + +C C GF
Sbjct: 1028 EAQCVQECGKGYFADHAKHKCTACPQG----CLQCSHRD------------RCHLCDHGF 1071
Query: 2014 WNYTKDGCDHCNCNTGYSV 2032
+ K G NC G+SV
Sbjct: 1072 --FLKSGLCVYNCVPGFSV 1088
Score = 38.7 bits (86), Expect = 0.39
Identities = 123/568 (21%), Positives = 192/568 (33%), Gaps = 92/568 (16%)
Query: 253 VCRCQHNT--CGPQ-CNKCCSGFEQKKWRISQNWDRFSCEPCNCHNHTTECTYDPEIDEK 309
VC C H C PQ C G ++ + I + SC P C C+Y+ + +
Sbjct: 115 VCSCNHGEVRCTPQPCPPLSCGHQELAF-IPEG----SCCPV-CVGLGKPCSYEGHVFQD 168
Query: 310 RLSLDINGRYEGGGKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFST 369
+ R KCL C++ +C+P + DE V P +C P S
Sbjct: 169 ----GEDWRLSRCAKCL-CRNGVAQCFTAQCQPLFCNQ-----DETVVRVPGKCCPQCSA 218
Query: 370 GNCEEESGRCECRPEFQPPDCSSCAYGYFDY----PNCKPCTC-------NLNGTEGEHC 418
+C E ++ C++C + C P C +G E C
Sbjct: 219 RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCEEC 278
Query: 419 TPTDGLCP----CKYN---YAGKSCE--ICEDGY---YSPECKNCECNTVGSVSYVCDKL 466
G C +Y + G +CE +C+ G + EC EC + ++ K
Sbjct: 279 VSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKC 338
Query: 467 TGDCTCKSKYSGRTCNQCQAGYYNYPTCKPCNCDTSGTE----P-SICDDVSGQCICKAG 521
+C ++ Y C + G + G + P +C+ Q C
Sbjct: 339 CPECISRNGY----CVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYE- 393
Query: 522 FGGPRCDQCLSG-YYMQVLGR-ERQCVPCNCDPTGST-STSCSADGKCNCLTNF--GGAQ 576
P C C G ++V G+ C +C P T S S C T G
Sbjct: 394 ---PSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWC 450
Query: 577 CDQCSPGYYKYPD-CLSCNCDVSG-SIGSTCDDNGLCHCKSNFDGAKC-DTCREQFY-NY 632
C G+Y+ CL+C S + G C C +C TC + FY +
Sbjct: 451 VHSCGLGFYQAGSLCLACQPQCSTCTSGLECSS---CQPPLLMRHGQCVPTCGDGFYQDR 507
Query: 633 PACEECNCDPRGVTASFAGCGSVPAGELCQCKDRV----QGRICNDCKPLYWNLQEYNPF 688
+C C+ S AGC C+D + G + C ++N Q
Sbjct: 508 HSCAVCH-------ESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQG---- 556
Query: 689 GCEQCNCNLAGTLNSLGACNTKSGQCVCKQHVGERQC-DQCLDGFYRLQTNDVFGCTECD 747
C C+ + +S G + + C K + + +C +C G+Y T C
Sbjct: 557 TCSACD----QSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHNSC 612
Query: 748 CDIGGSIDNNC-----DKTTGQCHCHSR 770
G ++C K Q HC R
Sbjct: 613 ASCSGPTPSHCTACSPPKALRQGHCLPR 640
Score = 37.9 bits (84), Expect = 0.68
Identities = 80/348 (22%), Positives = 110/348 (31%), Gaps = 39/348 (11%)
Query: 1749 QCAEGHYRLPS-GFCVPCQCNGHSDQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVG 1807
+C +G R G C +C + C + G+ + G CEFCM HG T
Sbjct: 260 RCGKGQSRARRHGQCCE-ECVSPAGSCSYD-GVVRYQDEMWKGSACEFCMCD-HGQVTCQ 316
Query: 1808 TPRDCLI-CA------------CPMPYPSNNFALSCDLSENGSLISCNCQPGYGGARCEY 1854
T + CA CP N + C E G +S N E
Sbjct: 317 TGECAKVECARDEELIHLDGKCCPECISRNGY---CVYEETGEFMSSNASEVKRIPEGEK 373
Query: 1855 CAAGYYGIPEDTDLHTGDY---CKPC---NCSGNINPQDPGSCDSIN--GDCLKCVNNTA 1906
G + E Y C PC + + Q C S++ DCL C + +
Sbjct: 374 WEDGPCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTC--SQS 431
Query: 1907 GAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV--CRPGVIGEKCDRCAPD 1964
C+LC + C G S C C G +C C P
Sbjct: 432 PDHCDLCQDP---TKLLQNGWCVHSCG-LGFYQAGSLCLACQPQCSTCTSGLECSSCQPP 487
Query: 1965 HWGLNTGLGCTPCNCGIASESTQCDDDNGQCRCAKGVTGKQCDQCAAGFWNYTKDGCDHC 2024
+ G C G + C + C G T K C C GC+
Sbjct: 488 LL-MRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCES- 545
Query: 2025 NCNTG-YSVGFMCNATGQCECLPGVIGEKCDRCPERWVLIPQEGCLEC 2071
+C G Y+ C+A Q G +C C E+ VL + EC
Sbjct: 546 SCGKGFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSEC 593
>Z99289-7|CAI42332.1| 177|Homo sapiens laminin, alpha 4 protein.
Length = 177
Score = 73.7 bits (173), Expect = 1e-11
Identities = 29/58 (50%), Positives = 34/58 (58%), Gaps = 3/58 (5%)
Query: 1891 CDSINGDCLKCVNNTAGAACNLCAPGFYGDAIFSKNCTACICDEFGMADCDSTTGTCV 1948
CD + G C C+ NT G C CAPG+YGDA +KNC C C G CDS TG C+
Sbjct: 5 CDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGPCDSVTGECL 59
Score = 52.0 bits (119), Expect = 4e-05
Identities = 21/46 (45%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 1772 DQCDVNTGICLNCADNTIGDHCEFCMSGYHGDATVGTPRDCLICAC 1817
+ CD TG C NC NT G CE C GY+GDA + ++C +C C
Sbjct: 3 EDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 46
Score = 50.8 bits (116), Expect = 9e-05
Identities = 30/85 (35%), Positives = 36/85 (42%), Gaps = 10/85 (11%)
Query: 1939 DCDSTTGTCV-CRPGVIGEKCDRCAPDHWG-LNTGLGCTPCNCGIASESTQCDDDNGQC- 1995
DCD TG C C G KC+RCAP ++G C CNCG CD G+C
Sbjct: 4 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG----GGPCDSVTGECL 59
Query: 1996 -RCAKGVTGKQCD--QCAAGFWNYT 2017
+ TG C C W+ T
Sbjct: 60 EEGFEPPTGMDCPTISCDKCVWDLT 84
Score = 47.2 bits (107), Expect = 0.001
Identities = 24/59 (40%), Positives = 28/59 (47%), Gaps = 12/59 (20%)
Query: 1842 NCQPGYGGARCEYCAAGYYGIPEDTDLHTGDYCKPCNCSGNINPQDPGSCDSINGDCLK 1900
NC G +CE CA GYYG D C CNC G G CDS+ G+CL+
Sbjct: 14 NCLRNTTGFKCERCAPGYYG-----DARIAKNCAVCNCGG-------GPCDSVTGECLE 60
Score = 46.8 bits (106), Expect = 0.001
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 11/73 (15%)
Query: 463 CDKLTGDC-TCKSKYSGRTCNQCQAGYYN----YPTCKPCNCDTSGTEPSICDDVSGQCI 517
CD++TG C C +G C +C GYY C CNC G P CD V+G+C+
Sbjct: 5 CDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGP--CDSVTGECL 59
Query: 518 CKAGFGGPRCDQC 530
+ GF P C
Sbjct: 60 -EEGFEPPTGMDC 71
Score = 44.4 bits (100), Expect = 0.008
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 9/59 (15%)
Query: 1988 CDDDNGQCR-CAKGVTGKQCDQCAAGFWNYTK--DGCDHCNCNTGYSVGFMCNA-TGQC 2042
CD+ GQCR C + TG +C++CA G++ + C CNC G C++ TG+C
Sbjct: 5 CDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG-----PCDSVTGEC 58
Score = 42.7 bits (96), Expect = 0.024
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 9/71 (12%)
Query: 323 GKCLNCQHNTEGINCNKCRPTYYRPYGKRWDELDVCQPCQCDPHFSTGNCEEESGRCECR 382
G+C NC NT G C +C P YY + C C C G C+ +G C
Sbjct: 10 GQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC----GGGPCDSVTGEC-LE 60
Query: 383 PEFQPPDCSSC 393
F+PP C
Sbjct: 61 EGFEPPTGMDC 71
Score = 41.9 bits (94), Expect = 0.042
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 509 CDDVSGQCI-CKAGFGGPRCDQCLSGYYMQVLGRERQCVPCNC--DPTGSTSTSCSADG 564
CD+V+GQC C G +C++C GYY + C CNC P S + C +G
Sbjct: 5 CDEVTGQCRNCLRNTTGFKCERCAPGYYGDA-RIAKNCAVCNCGGGPCDSVTGECLEEG 62
Score = 41.1 bits (92), Expect = 0.073
Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
Query: 564 GKC-NCLTNFGGAQCDQCSPGYYKYPDCLSCNCDVSGSIGSTCDD-NGLC 611
G+C NCL N G +C++C+PGYY ++ NC V G CD G C
Sbjct: 10 GQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGGGPCDSVTGEC 58
Score = 40.7 bits (91), Expect = 0.097
Identities = 24/59 (40%), Positives = 26/59 (44%), Gaps = 7/59 (11%)
Query: 416 EHCTPTDGLCP-CKYNYAGKSCEICEDGYYSPE--CKNCE-CNTVGSVSYVCDKLTGDC 470
E C G C C N G CE C GYY KNC CN G CD +TG+C
Sbjct: 3 EDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG---PCDSVTGEC 58
Score = 37.1 bits (82), Expect = 1.2
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 7/52 (13%)
Query: 1735 ECQ-CPRAYRGLSCEQCAEGHY---RLPSGFCVPCQCNGHSDQCDVNTGICL 1782
+C+ C R G CE+CA G+Y R+ C C C G CD TG CL
Sbjct: 11 QCRNCLRNTTGFKCERCAPGYYGDARIAKN-CAVCNCGG--GPCDSVTGECL 59
Score = 34.3 bits (75), Expect = 8.4
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 10/59 (16%)
Query: 1444 CEADSGKCA-CRENVRGRVCDHCVPGHYA----FPDCYQCTCNRHGTTYDVCDQNTAQC 1497
C+ +G+C C N G C+ C PG+Y +C C C CD T +C
Sbjct: 5 CDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGEC 58
>AK057327-1|BAB71429.1| 721|Homo sapiens protein ( Homo sapiens cDNA
FLJ32765 fis, clone TESTI2001852, weakly similar to Homo
sapiens contactin associated protein (Caspr) mRNA. ).
Length = 721
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/351 (24%), Positives = 143/351 (40%), Gaps = 43/351 (12%)
Query: 2665 VSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDP- 2723
+S F+T + DG +L+ P G D++ + ++ +++++ G++ P
Sbjct: 183 ISLKFKTMQSDGILLHREGPNG---------DHITLQLRRARLFLLINSGEAKLPSTSTL 233
Query: 2724 ARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKE 2783
+++ ++ D W+ V++ RLG++V ++ E H G + NLD E
Sbjct: 234 VNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDE---------HRHHFHARGEFNLMNLDYE 284
Query: 2784 KSKLYVGGVPSDAKLQGISFP--AFEGQIEELMI-GDTPVGLWNFVSANKLKGARQRDKL 2840
S GG+P+ K +SFP F G +E L G + L +
Sbjct: 285 IS---FGGIPAPGK--SVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSC 339
Query: 2841 ISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYL----VGEGGYFF 2896
QS P + R Y +A + + FRT+ GL+ + GG
Sbjct: 340 SQPQSMPVTF-LSSRSY--LALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL- 395
Query: 2897 SLLMQDGRVYLQV-SLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAE 2955
L + DG++ + G I G NDG+WH + S+ VD ++ A
Sbjct: 396 -LFLSDGKLKSNLYQPGKLPSDITAGV--ELNDGQWHSVSLSAKKNHLSVAVDGQMASAA 452
Query: 2956 SNSPSADIPSLDTMNFGG-NNKGI---LQVPDRGFDGCMRQISINGVNLDL 3002
I S T FGG +K + P GF GCMR ISI+G +DL
Sbjct: 453 PLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDL 503
Score = 72.5 bits (170), Expect = 3e-11
Identities = 83/335 (24%), Positives = 154/335 (45%), Gaps = 29/335 (8%)
Query: 2866 LTPQSNQVLLFFRTYAPNG-LIYLVGEGGYFFSLLMQDGRVYLQVSLG-----NTEDLII 2919
L+P + + L F+T +G L++ G G +L ++ R++L ++ G +T L+
Sbjct: 176 LSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVN 235
Query: 2920 VGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLD-TMNFGG---NN 2975
+ +D WH + +R + + TVD + ++ +LD ++FGG
Sbjct: 236 LTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARG-EFNLMNLDYEISFGGIPAPG 294
Query: 2976 KGILQVPDRGFDGCMRQISINGVN-LDLSE----NLESIG-MAYGC-QFASL-VSFNGTD 3027
K + P R F GC+ + NGV+ +DL++ + ++G +++ C Q S+ V+F +
Sbjct: 295 KSV-SFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSR 353
Query: 3028 SYLRFVDVTSENP-QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV-VSQ 3085
SYL D + E T +F+T GLL ++ ++ I L L +GKL + Q
Sbjct: 354 SYLALPDFSGEEEVSATFQFRTWNKAGLLLF----SELQLISGGILLFLSDGKLKSNLYQ 409
Query: 3086 REQLDTGLNT---YNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIG 3142
+L + + ND QWH ++++ + L + VD + P G + G
Sbjct: 410 PGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFG 469
Query: 3143 GVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLL 3177
G S F GC+ +I+G+V++L+
Sbjct: 470 GCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLI 504
Score = 43.6 bits (98), Expect = 0.014
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
Query: 3329 EGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHY-MFNCGGETGVISST 3387
E T FRT++K G++ ++E + F+ D KL ++ G I++
Sbjct: 365 EEVSATFQFRTWNK-AGLLLFSELQLISGGI---LLFLSDGKLKSNLYQPGKLPSDITAG 420
Query: 3388 HTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISK 3447
ND WH+V+L+ H +AVD +M + + YY+GG ++
Sbjct: 421 VELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGC--PDKSFGS 478
Query: 3448 IFDNFYQPFMGCLKGLLMNGQQVTRI 3473
+ F GC++ + ++G+ V I
Sbjct: 479 KCKSPLGGFQGCMRLISISGKVVDLI 504
Score = 39.5 bits (88), Expect = 0.22
Identities = 69/328 (21%), Positives = 122/328 (37%), Gaps = 30/328 (9%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYN- 3391
+++ F+T G ++ + E + + + +R A+L + N GE + S++ N
Sbjct: 183 ISLKFKTMQSDG-ILLHREGPNGDH----ITLQLRRARLFLLIN-SGEAKLPSTSTLVNL 236
Query: 3392 -------DIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNER 3444
D WH+V + R G VD + ++L +GG+ +
Sbjct: 237 TLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIPAPGKS 296
Query: 3445 ISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNA-LRCVDNIEDGVYFEASNNT---HS 3500
+S NF+ GCL+ L NG + + + + N+ S S
Sbjct: 297 VSFPHRNFH----GCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSS 352
Query: 3501 NYLKLLENFKVGDEVSISMEVRPRNTTGLLL--SVHGKKDYMVLELLDSEVVANVENGNG 3558
L +F +EVS + + R N GLLL + ++L L D ++ +N+
Sbjct: 353 RSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQ--- 409
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSK--PGIGAYTSTDTHSALYI 3616
P + ++ L DG WH + DG + P +G + Y
Sbjct: 410 PGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGP-EQIYSGGTYYF 468
Query: 3617 GGHERPIHKVRGVHSRRGFTGCVRNIVV 3644
GG + GF GC+R I +
Sbjct: 469 GGCPDKSFGSKCKSPLGGFQGCMRLISI 496
>AF463518-1|AAL68839.1| 1311|Homo sapiens cell recognition protein
CASPR4 protein.
Length = 1311
Score = 72.9 bits (171), Expect = 2e-11
Identities = 87/351 (24%), Positives = 143/351 (40%), Gaps = 43/351 (12%)
Query: 2665 VSAYFRTKEKDGFILYLGNPKGTMLRRTKSDDYMVIGIQNGYPYVVMDIGDSSEPGQDP- 2723
+S F+T + DG +L+ P G D++ + ++ +++++ G++ P
Sbjct: 211 ISLKFKTMQSDGILLHREGPNG---------DHITLQLRRARLFLLINSGEAKLPSTSTL 261
Query: 2724 ARVSIDKMVADNRWYQVIVDRLGRRVKLSIRESLDNGTDTIHSKEADLPGHHTIFNLDKE 2783
+++ ++ D W+ V++ RLG++V ++ E H G + NLD E
Sbjct: 262 VNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDE---------HRHHFHARGEFNLMNLDYE 312
Query: 2784 KSKLYVGGVPSDAKLQGISFP--AFEGQIEELMI-GDTPVGLWNFVSANKLKGARQRDKL 2840
S GG+P+ K +SFP F G +E L G + L +
Sbjct: 313 IS---FGGIPAPGK--SVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSC 367
Query: 2841 ISSQSGPQEYRFDGRGYATMAGRGYLTPQSNQVLLFFRTYAPNGLIYL----VGEGGYFF 2896
QS P + R Y +A + + FRT+ GL+ + GG
Sbjct: 368 SQPQSMPVTF-LSSRSY--LALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL- 423
Query: 2897 SLLMQDGRVYLQV-SLGNTEDLIIVGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAE 2955
L + DG++ + G I G NDG+WH + S+ VD ++ A
Sbjct: 424 -LFLSDGKLKSNLYQPGKLPSDITAGV--ELNDGQWHSVSLSAKKNHLSVAVDGQMASAA 480
Query: 2956 SNSPSADIPSLDTMNFGG-NNKGI---LQVPDRGFDGCMRQISINGVNLDL 3002
I S T FGG +K + P GF GCMR ISI+G +DL
Sbjct: 481 PLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDL 531
Score = 72.5 bits (170), Expect = 3e-11
Identities = 83/335 (24%), Positives = 154/335 (45%), Gaps = 29/335 (8%)
Query: 2866 LTPQSNQVLLFFRTYAPNG-LIYLVGEGGYFFSLLMQDGRVYLQVSLG-----NTEDLII 2919
L+P + + L F+T +G L++ G G +L ++ R++L ++ G +T L+
Sbjct: 204 LSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVN 263
Query: 2920 VGTTRAYNDGKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIPSLD-TMNFGG---NN 2975
+ +D WH + +R + + TVD + ++ +LD ++FGG
Sbjct: 264 LTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARG-EFNLMNLDYEISFGGIPAPG 322
Query: 2976 KGILQVPDRGFDGCMRQISINGVN-LDLSE----NLESIG-MAYGC-QFASL-VSFNGTD 3027
K + P R F GC+ + NGV+ +DL++ + ++G +++ C Q S+ V+F +
Sbjct: 323 KSV-SFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSR 381
Query: 3028 SYLRFVDVTSENP-QLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSLVNGKLVV-VSQ 3085
SYL D + E T +F+T GLL ++ ++ I L L +GKL + Q
Sbjct: 382 SYLALPDFSGEEEVSATFQFRTWNKAGLLLF----SELQLISGGILLFLSDGKLKSNLYQ 437
Query: 3086 REQLDTGLNT---YNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHILDGVLFIG 3142
+L + + ND QWH ++++ + L + VD + P G + G
Sbjct: 438 PGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFG 497
Query: 3143 GVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLL 3177
G S F GC+ +I+G+V++L+
Sbjct: 498 GCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLI 532
Score = 52.4 bits (120), Expect = 3e-05
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 6/140 (4%)
Query: 2870 SNQVLLFFRTYAPNGL-IYLVGEGGYFFSLLMQDGRVYLQVSLGNTEDLIIVGTTRAYND 2928
S V FF+T A +G+ + +G + L V +GN I V + +ND
Sbjct: 817 SADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFND 876
Query: 2929 GKWHKLDARRFLAKCSLTVDNEVLKAESNSPSADIP-SLDTMNFGGNNKGILQVPDRGFD 2987
+WH + R + + SL VD K + + L++ F G RGF
Sbjct: 877 NQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTA----TRQRGFL 932
Query: 2988 GCMRQISINGVNLDLSENLE 3007
GC+R + +NG+ LDL E +
Sbjct: 933 GCIRSLQLNGMTLDLEERAQ 952
Score = 43.6 bits (98), Expect = 0.014
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
Query: 3329 EGFDLTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHY-MFNCGGETGVISST 3387
E T FRT++K G++ ++E + F+ D KL ++ G I++
Sbjct: 393 EEVSATFQFRTWNK-AGLLLFSELQLISGGI---LLFLSDGKLKSNLYQPGKLPSDITAG 448
Query: 3388 HTYNDIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNERISK 3447
ND WH+V+L+ H +AVD +M + + YY+GG ++
Sbjct: 449 VELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGC--PDKSFGS 506
Query: 3448 IFDNFYQPFMGCLKGLLMNGQQVTRI 3473
+ F GC++ + ++G+ V I
Sbjct: 507 KCKSPLGGFQGCMRLISISGKVVDLI 532
Score = 40.3 bits (90), Expect = 0.13
Identities = 47/167 (28%), Positives = 70/167 (41%), Gaps = 16/167 (9%)
Query: 3017 FASLVSFNGTDSYLRFVDVTSE-NPQLTLKFKTAKPNGLLFVYVSRTQTAIMPDSISLSL 3075
F + SF+ SYL F E + ++ FKT +G+ F+ I + S ++
Sbjct: 794 FWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGV-FLENLGIADFIRIELRSPTV 852
Query: 3076 VNGKLVVVSQREQLDTGLNT-YNDSQWHVLTVTHNTSALKLVVDDFDYFSTDTAPPPLHI 3134
V V + ++ T +ND+QWH + V N L VD T AP H+
Sbjct: 853 VTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTP-KTQPAPADGHV 911
Query: 3135 ---LDGVLFIGGVQPGYVVSGSLGSKVPFTGCIGDATINGQVLNLLE 3178
L+ LF+GG + G F GCI +NG L+L E
Sbjct: 912 LLQLNSQLFVGG-----TATRQRG----FLGCIRSLQLNGMTLDLEE 949
Score = 39.5 bits (88), Expect = 0.22
Identities = 69/328 (21%), Positives = 122/328 (37%), Gaps = 30/328 (9%)
Query: 3333 LTISFRTFDKQGGVIFYAESAHDKNPVQFLAFFMRDAKLHYMFNCGGETGVISSTHTYN- 3391
+++ F+T G ++ + E + + + +R A+L + N GE + S++ N
Sbjct: 211 ISLKFKTMQSDG-ILLHREGPNGDH----ITLQLRRARLFLLIN-SGEAKLPSTSTLVNL 264
Query: 3392 -------DIDWHTVTLTRNGGHGKLAVDSEMVGETSVTCNTPLSLAPPYYYGGLRYVNER 3444
D WH+V + R G VD + ++L +GG+ +
Sbjct: 265 TLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIPAPGKS 324
Query: 3445 ISKIFDNFYQPFMGCLKGLLMNGQQVTRIGNAVNA-LRCVDNIEDGVYFEASNNT---HS 3500
+S NF+ GCL+ L NG + + + + N+ S S
Sbjct: 325 VSFPHRNFH----GCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSS 380
Query: 3501 NYLKLLENFKVGDEVSISMEVRPRNTTGLLL--SVHGKKDYMVLELLDSEVVANVENGNG 3558
L +F +EVS + + R N GLLL + ++L L D ++ +N+
Sbjct: 381 RSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQ--- 437
Query: 3559 PFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSK--PGIGAYTSTDTHSALYI 3616
P + ++ L DG WH + DG + P +G + Y
Sbjct: 438 PGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGP-EQIYSGGTYYF 496
Query: 3617 GGHERPIHKVRGVHSRRGFTGCVRNIVV 3644
GG + GF GC+R I +
Sbjct: 497 GGCPDKSFGSKCKSPLGGFQGCMRLISI 524
Score = 37.1 bits (82), Expect = 1.2
Identities = 39/154 (25%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 3494 ASNNTHSNYLKLLENFKVGDEVSISMEVRPRNTTGLLLSVHGKKDYMVLELLDSEVVA-N 3552
AS +T ++YL F +S + ++G+ L G D++ +EL VV +
Sbjct: 798 ASFDTEASYLHF-PTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFS 856
Query: 3553 VENGNGPFRATYKLSNKHYLCDGNWHKIHXXXXXXXXXXXXDGHFSK----PGIGAYTST 3608
+ GNGPF + + S H+ D WH + D K P G +
Sbjct: 857 FDVGNGPFEISVQ-SPTHFN-DNQWHHVRVERNMKEASLQVDQLTPKTQPAPADG-HVLL 913
Query: 3609 DTHSALYIGGHERPIHKVRGVHSRRGFTGCVRNI 3642
+S L++GG +RGF GC+R++
Sbjct: 914 QLNSQLFVGGTAT---------RQRGFLGCIRSL 938
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.136 0.429
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 570,556,547
Number of Sequences: 224733
Number of extensions: 26990894
Number of successful extensions: 108023
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 318
Number of HSP's successfully gapped in prelim test: 833
Number of HSP's that attempted gapping in prelim test: 55116
Number of HSP's gapped (non-prelim): 19999
length of query: 3668
length of database: 73,234,838
effective HSP length: 104
effective length of query: 3564
effective length of database: 49,862,606
effective search space: 177710327784
effective search space used: 177710327784
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 75 (34.3 bits)
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