Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002014-TA|BGIBMGA002014-PA|IPR008271|Serine/threonine
protein kinase, active site, IPR000719|Protein kinase,
IPR002290|Serine/threonine protein kinase, IPR011009|Protein
kinase-like
(961 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U48736-1|AAB03268.1| 496|Homo sapiens serine/threonine-protein ... 471 e-132
BC009844-1|AAH09844.1| 496|Homo sapiens PRPF4B protein protein. 471 e-132
AY029347-1|AAK38155.1| 1007|Homo sapiens serine/threonine-protei... 471 e-132
AL138831-3|CAI20480.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 471 e-132
AL033383-1|CAI42121.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 471 e-132
AF283465-1|AAM19101.1| 1007|Homo sapiens PRP4 kinase protein. 471 e-132
AB011108-1|BAA25462.1| 1028|Homo sapiens KIAA0536 protein protein. 471 e-132
BC034969-1|AAH34969.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 469 e-131
U58496-1|AAC50939.1| 763|Homo sapiens hp86 protein. 138 7e-32
U52373-1|AAB18639.1| 763|Homo sapiens MNB protein. 138 7e-32
D86550-1|BAA13110.1| 754|Homo sapiens serine/threonine protein ... 138 7e-32
D85759-1|BAA12866.1| 754|Homo sapiens MNB protein kinase protein. 138 7e-32
AF108830-1|AAD31169.1| 584|Homo sapiens serine-threonine protei... 138 7e-32
BC031244-1|AAH31244.1| 520|Homo sapiens dual-specificity tyrosi... 138 1e-31
AF326592-1|AAL37371.1| 1171|Homo sapiens homeodomain interacting... 138 1e-31
AF263541-1|AAF91393.1| 541|Homo sapiens protein kinase DYRK4 pr... 138 1e-31
AL122015-2|CAJ55828.1| 1194|Homo sapiens homeodomain interacting... 136 3e-31
AL122015-1|CAC13164.1| 1215|Homo sapiens homeodomain interacting... 136 3e-31
AF305239-1|AAG25990.1| 1194|Homo sapiens Fas-interacting serine/... 136 3e-31
AF004849-1|AAC64294.1| 1215|Homo sapiens PKY protein kinase prot... 136 3e-31
Y17999-3|CAA76990.1| 589|Homo sapiens Dyrk1B protein kinase pro... 136 4e-31
Y17999-2|CAA76989.1| 601|Homo sapiens Dyrk1B protein kinase pro... 136 4e-31
Y17999-1|CAA76991.1| 629|Homo sapiens Dyrk1B protein kinase pro... 136 4e-31
BC025291-1|AAH25291.1| 629|Homo sapiens dual-specificity tyrosi... 136 4e-31
BC018751-1|AAH18751.1| 629|Homo sapiens dual-specificity tyrosi... 136 4e-31
AF205861-1|AAF15893.1| 629|Homo sapiens protein kinase MIRK pro... 136 4e-31
AF208291-1|AAG41236.1| 1198|Homo sapiens protein kinase HIPK2 pr... 136 5e-31
AF207702-1|AAG35710.1| 911|Homo sapiens homeodomain-interacting... 135 6e-31
Y13493-1|CAA73885.1| 528|Homo sapiens protein kinase Dyrk2 prot... 133 2e-30
BC006375-1|AAH06375.1| 601|Homo sapiens DYRK2 protein protein. 133 2e-30
BC005809-1|AAH05809.1| 528|Homo sapiens dual-specificity tyrosi... 133 2e-30
AY590695-1|AAT06103.1| 588|Homo sapiens dual-specificity tyrosi... 133 2e-30
AL591846-9|CAI13541.1| 568|Homo sapiens dual-specificity tyrosi... 133 2e-30
AL591846-7|CAI13539.1| 588|Homo sapiens dual-specificity tyrosi... 133 2e-30
AF327561-1|AAK16443.1| 568|Homo sapiens dual-specificity tyrosi... 133 2e-30
AF186774-1|AAG17029.1| 568|Homo sapiens regulatory erythroid ki... 133 2e-30
AF186773-1|AAG17028.1| 588|Homo sapiens regulatory erythroid ki... 133 2e-30
Y12735-1|CAA73266.2| 588|Homo sapiens Dyrk3 protein protein. 133 3e-30
BC015501-1|AAH15501.1| 568|Homo sapiens dual-specificity tyrosi... 131 1e-29
BC033012-1|AAH33012.1| 1075|Homo sapiens homeodomain interacting... 129 4e-29
AL731797-3|CAI22793.1| 1210|Homo sapiens homeodomain interacting... 129 4e-29
AL731797-2|CAI22794.1| 1165|Homo sapiens homeodomain interacting... 129 4e-29
AL731797-1|CAI22792.1| 1075|Homo sapiens homeodomain interacting... 129 4e-29
AB089957-1|BAC57075.1| 1210|Homo sapiens homeodomain-interacting... 129 4e-29
AC005393-2|AAC28914.1| 556|Homo sapiens BC331004_1 protein. 122 5e-27
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 119 4e-26
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 119 4e-26
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 119 4e-26
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 119 4e-26
BC034501-1|AAH34501.1| 616|Homo sapiens homeodomain interacting... 118 8e-26
AK057380-1|BAB71458.1| 541|Homo sapiens protein ( Homo sapiens ... 109 3e-23
L29218-1|AAA61482.1| 499|Homo sapiens clk2 protein. 108 1e-22
BC053603-1|AAH53603.1| 499|Homo sapiens CDC-like kinase 2 protein. 108 1e-22
BC014067-1|AAH14067.1| 498|Homo sapiens CDC-like kinase 2 protein. 108 1e-22
AL713999-30|CAI95098.1| 498|Homo sapiens CDC-like kinase 2 prot... 108 1e-22
AL713999-29|CAI95097.1| 497|Homo sapiens CDC-like kinase 2 prot... 108 1e-22
AL713999-28|CAI95099.1| 499|Homo sapiens CDC-like kinase 2 prot... 108 1e-22
AF023268-1|AAC51817.1| 499|Homo sapiens clk2 kinase protein. 108 1e-22
BT006993-1|AAP35639.1| 490|Homo sapiens CDC-like kinase 3 protein. 105 1e-21
BC019881-1|AAH19881.1| 490|Homo sapiens CLK3 protein protein. 105 1e-21
BC002555-1|AAH02555.1| 490|Homo sapiens CDC-like kinase 3 protein. 105 1e-21
L29217-1|AAA61484.1| 490|Homo sapiens clk3 protein. 104 1e-21
AB209535-1|BAD92772.1| 565|Homo sapiens Dual specificity protei... 104 1e-21
X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal regu... 103 2e-21
Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein ... 102 5e-21
U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein. 102 5e-21
BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated prote... 102 5e-21
AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated prot... 102 5e-21
U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein. 101 9e-21
Z95152-3|CAB08438.1| 365|Homo sapiens mitogen-activated protein... 101 1e-20
Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein ... 101 1e-20
U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein. 101 1e-20
CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein. 101 1e-20
CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein. 101 1e-20
BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated prote... 101 1e-20
BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated prote... 101 1e-20
BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated prote... 101 1e-20
BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated prote... 101 1e-20
AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protei... 101 1e-20
AJ001870-1|CAA05059.1| 147|Homo sapiens MNB protein kinase prot... 101 2e-20
AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated prote... 101 2e-20
L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase ... 100 5e-20
D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase ... 100 5e-20
BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinas... 100 5e-20
BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinas... 100 5e-20
AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragmen... 100 5e-20
AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein. 100 5e-20
AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protei... 99 7e-20
Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein ... 99 9e-20
U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein... 99 9e-20
DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated prote... 99 9e-20
CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein. 99 9e-20
BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated prote... 99 9e-20
AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated prot... 99 9e-20
AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase pro... 99 9e-20
AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated p... 99 9e-20
AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase pro... 99 9e-20
AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase pro... 99 9e-20
U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein. 98 2e-19
L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein pr... 98 2e-19
L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein. 98 2e-19
CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein. 98 2e-19
BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated prote... 98 2e-19
BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated prote... 98 2e-19
BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated prote... 98 2e-19
AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protei... 98 2e-19
AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced var... 98 2e-19
L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein pr... 97 3e-19
BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein. 95 8e-19
AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase prot... 95 8e-19
U35003-1|AAC50609.1| 424|Homo sapiens JNK2 beta2 protein kinase... 95 1e-18
U35002-1|AAC50608.1| 382|Homo sapiens JNK2 beta1 protein kinase... 95 1e-18
U34820-1|AAC50605.1| 422|Homo sapiens JNK3 alpha1 protein kinas... 95 1e-18
U34819-1|AAC50604.1| 464|Homo sapiens JNK3 alpha2 protein kinas... 95 1e-18
U07620-1|AAC50101.1| 422|Homo sapiens MAP kinase protein. 95 1e-18
L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein. 95 1e-18
CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein. 95 1e-18
BC035057-1|AAH35057.1| 464|Homo sapiens MAPK10 protein protein. 95 1e-18
BC022025-1|AAH22025.1| 493|Homo sapiens CLK2P protein protein. 95 1e-18
BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein. 95 1e-18
BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinas... 95 1e-18
U34822-1|AAC50607.1| 427|Homo sapiens JNK1 alpha2 protein kinas... 95 1e-18
U34821-1|AAC50606.1| 382|Homo sapiens JNK2 alpha1 protein kinas... 95 1e-18
L31951-1|AAA56831.1| 424|Homo sapiens protein kinase protein. 95 1e-18
L26318-1|AAA36131.1| 384|Homo sapiens protein kinase protein. 95 1e-18
U09759-1|AAA74740.1| 424|Homo sapiens protein kinase protein. 94 2e-18
DQ066599-1|AAY46156.1| 424|Homo sapiens mitogen-activated prote... 94 2e-18
CR536580-1|CAG38817.1| 424|Homo sapiens MAPK9 protein. 94 2e-18
BC032539-1|AAH32539.1| 424|Homo sapiens mitogen-activated prote... 94 2e-18
U35005-1|AAC50611.1| 427|Homo sapiens JNK1 beta2 protein kinase... 93 3e-18
U35004-1|AAC50610.1| 384|Homo sapiens JNK1 beta1 protein kinase... 93 3e-18
BC130572-1|AAI30573.1| 427|Homo sapiens mitogen-activated prote... 93 3e-18
BC130570-1|AAI30571.1| 427|Homo sapiens mitogen-activated prote... 93 3e-18
L29219-1|AAA61480.1| 484|Homo sapiens clk1 protein. 93 4e-18
BC031549-1|AAH31549.1| 484|Homo sapiens CDC-like kinase 1 protein. 93 4e-18
AC005037-5|AAY14722.1| 484|Homo sapiens unknown protein. 93 4e-18
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 92 8e-18
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 92 8e-18
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 92 8e-18
AF294429-1|AAG10074.1| 481|Homo sapiens protein serine threonin... 91 1e-17
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 91 2e-17
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 91 2e-17
AY065978-1|AAL40897.1| 544|Homo sapiens extracellular signal-re... 89 5e-17
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 89 9e-17
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 89 9e-17
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 89 9e-17
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 89 9e-17
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 89 9e-17
X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein ... 87 2e-16
BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase... 87 2e-16
BC051731-1|AAH51731.1| 319|Homo sapiens MAPK10 protein protein. 87 2e-16
AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase... 87 2e-16
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 87 4e-16
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 87 4e-16
BC065516-1|AAH65516.1| 319|Homo sapiens MAPK10 protein protein. 86 5e-16
AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated... 86 5e-16
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 86 7e-16
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 85 9e-16
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 85 9e-16
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 85 9e-16
U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein. 85 1e-15
U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4... 85 1e-15
M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein ... 85 1e-15
CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein. 85 1e-15
CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein. 85 1e-15
BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase... 85 1e-15
BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase... 85 1e-15
BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase... 85 1e-15
AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase... 85 1e-15
Z95152-2|CAI19690.1| 355|Homo sapiens mitogen-activated protein... 85 2e-15
CR456515-1|CAG30401.1| 357|Homo sapiens MAPK12 protein. 84 2e-15
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 84 2e-15
Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase prot... 84 3e-15
M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein. 84 3e-15
BX640648-1|CAE45794.1| 319|Homo sapiens hypothetical protein pr... 84 3e-15
BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated prote... 84 3e-15
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 83 5e-15
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 83 5e-15
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 83 5e-15
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 83 5e-15
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 83 5e-15
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 83 6e-15
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 83 6e-15
AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kina... 83 6e-15
AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kina... 83 6e-15
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 82 8e-15
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 82 8e-15
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 82 8e-15
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 82 8e-15
DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein. 82 8e-15
BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein. 82 8e-15
BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated prote... 82 8e-15
BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated prote... 82 8e-15
AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated prote... 82 8e-15
AY033608-1|AAK52330.1| 335|Homo sapiens extracellular signal-re... 82 8e-15
AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein. 82 8e-15
AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein. 82 8e-15
Z48970-1|CAA88834.1| 303|Homo sapiens orf protein. 82 1e-14
X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine ... 82 1e-14
AY033607-1|AAK52329.1| 357|Homo sapiens extracellular signal-re... 82 1e-14
BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein. 81 1e-14
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 81 2e-14
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 81 2e-14
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 81 2e-14
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 81 2e-14
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 81 2e-14
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 81 2e-14
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 81 2e-14
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 81 2e-14
Z25435-1|CAA80922.1| 46|Homo sapiens protein-serine/threonine ... 80 3e-14
BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein. 80 3e-14
AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-l... 80 3e-14
AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase p... 80 3e-14
AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase p... 80 3e-14
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 80 4e-14
M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kina... 80 4e-14
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 80 4e-14
U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein ... 79 6e-14
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 79 7e-14
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 79 7e-14
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 79 7e-14
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 79 7e-14
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 79 7e-14
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 79 7e-14
BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein. 79 1e-13
AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein. 79 1e-13
AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein. 79 1e-13
AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase prot... 79 1e-13
AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein. 79 1e-13
AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase ... 77 2e-13
BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein. 77 3e-13
AL833829-1|CAD38689.1| 893|Homo sapiens hypothetical protein pr... 77 3e-13
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 77 3e-13
AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase ... 77 3e-13
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 77 3e-13
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 77 3e-13
Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase prot... 76 5e-13
Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein. 76 5e-13
M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein. 76 5e-13
DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated prote... 76 5e-13
BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated prote... 76 5e-13
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 76 7e-13
BC085196-1|AAH85196.1| 257|Homo sapiens MAPK13 protein protein. 75 1e-12
AB209611-1|BAD92848.1| 453|Homo sapiens Mitogen activated prote... 75 2e-12
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 74 2e-12
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 74 2e-12
BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated prote... 74 3e-12
AF390028-1|AAL58838.1| 993|Homo sapiens serine/threonine protei... 74 3e-12
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 74 3e-12
DQ234352-1|ABB29981.1| 308|Homo sapiens mitogen-activated prote... 73 4e-12
BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein pr... 73 4e-12
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 73 5e-12
BC007992-1|AAH07992.1| 677|Homo sapiens mitogen-activated prote... 73 5e-12
BC007404-1|AAH07404.1| 677|Homo sapiens mitogen-activated prote... 73 5e-12
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 73 5e-12
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 73 6e-12
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 73 6e-12
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 73 6e-12
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 73 6e-12
BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated prote... 72 9e-12
BC040529-1|AAH40529.1| 231|Homo sapiens PCTK3 protein protein. 72 1e-11
X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase prot... 71 2e-11
M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein. 71 2e-11
BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated prote... 71 2e-11
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 71 2e-11
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 71 2e-11
CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein. 71 3e-11
Z25423-1|CAA80910.1| 64|Homo sapiens protein-serine/threonine ... 70 3e-11
U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein. 70 3e-11
U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein. 70 3e-11
U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein. 70 3e-11
U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein. 70 3e-11
U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein. 70 3e-11
M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase pr... 70 3e-11
BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L1 protein protein. 70 3e-11
BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L1 protein protein. 70 3e-11
BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein. 70 3e-11
AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase ... 70 3e-11
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 70 5e-11
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 69 8e-11
BC006103-1|AAH06103.1| 467|Homo sapiens CLK3 protein protein. 69 8e-11
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 69 8e-11
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 69 8e-11
BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein pr... 69 1e-10
BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein. 69 1e-10
BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated prote... 69 1e-10
BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated prote... 69 1e-10
AL024498-4|CAB75823.1| 623|Homo sapiens protein ( Human DNA seq... 69 1e-10
AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associat... 69 1e-10
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 68 1e-10
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 68 1e-10
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 68 1e-10
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 68 1e-10
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 68 1e-10
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 68 1e-10
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 68 1e-10
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 68 1e-10
U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22 p... 68 2e-10
U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21 p... 68 2e-10
U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein. 68 2e-10
BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-l... 68 2e-10
BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein. 68 2e-10
BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein. 68 2e-10
AL031282-7|CAI20032.1| 783|Homo sapiens cell division cycle 2-l... 68 2e-10
AL031282-6|CAI20034.1| 780|Homo sapiens cell division cycle 2-l... 68 2e-10
AL031282-5|CAI20031.1| 779|Homo sapiens cell division cycle 2-l... 68 2e-10
AL031282-4|CAI20033.1| 770|Homo sapiens cell division cycle 2-l... 68 2e-10
AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-l... 68 2e-10
AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase ... 68 2e-10
AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase ... 68 2e-10
X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein. 67 2e-10
L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein. 67 2e-10
BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated prote... 67 2e-10
AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein. 67 2e-10
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 67 3e-10
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 67 3e-10
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 67 3e-10
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 67 3e-10
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 67 3e-10
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 67 3e-10
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 67 3e-10
AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1 pro... 67 3e-10
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 67 3e-10
L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein. 66 4e-10
BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated prote... 66 4e-10
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 66 6e-10
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 66 6e-10
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 66 6e-10
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 66 7e-10
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 66 7e-10
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 66 7e-10
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 66 7e-10
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 66 7e-10
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 65 1e-09
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 65 1e-09
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 65 1e-09
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 65 1e-09
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 65 1e-09
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 65 1e-09
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 65 1e-09
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 65 1e-09
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 65 1e-09
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 65 1e-09
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 65 1e-09
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 65 1e-09
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 65 1e-09
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 65 1e-09
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 65 1e-09
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 65 1e-09
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 65 1e-09
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 65 1e-09
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 65 1e-09
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 65 1e-09
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 65 1e-09
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 65 1e-09
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 65 1e-09
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 65 1e-09
AB209586-1|BAD92823.1| 255|Homo sapiens mitogen-activated prote... 65 1e-09
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 65 1e-09
AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3 p... 64 2e-09
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 64 2e-09
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 64 2e-09
U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b p... 64 2e-09
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 64 2e-09
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 64 2e-09
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 64 2e-09
CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein. 64 2e-09
BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated prote... 64 2e-09
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 64 2e-09
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 64 2e-09
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 64 2e-09
BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated prote... 64 2e-09
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 64 2e-09
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 64 2e-09
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 64 2e-09
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 64 2e-09
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 64 2e-09
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 64 2e-09
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 64 2e-09
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 64 2e-09
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 64 2e-09
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 64 2e-09
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 64 2e-09
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 64 2e-09
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 64 2e-09
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 64 2e-09
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 64 2e-09
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 64 2e-09
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 63 4e-09
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 63 4e-09
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 63 4e-09
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 63 4e-09
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 63 4e-09
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 63 4e-09
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 63 4e-09
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 63 4e-09
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 63 4e-09
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 63 5e-09
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 63 5e-09
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 63 5e-09
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 63 5e-09
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 63 5e-09
AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein. 63 5e-09
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 62 7e-09
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 62 7e-09
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 62 7e-09
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 62 7e-09
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 62 7e-09
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 62 7e-09
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 62 7e-09
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 62 7e-09
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 62 7e-09
AL022069-1|CAI19650.1| 166|Homo sapiens ribosomal protein S6 ki... 62 7e-09
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 62 7e-09
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 62 9e-09
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 62 9e-09
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 62 9e-09
AY112721-1|AAM52224.1| 391|Homo sapiens casein kinase II alpha ... 62 9e-09
AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 62 9e-09
AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 62 9e-09
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 62 9e-09
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 62 9e-09
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 62 9e-09
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 62 9e-09
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 62 9e-09
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 62 9e-09
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 62 9e-09
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 62 9e-09
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 62 9e-09
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 62 1e-08
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 62 1e-08
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 62 1e-08
Z95152-1|CAI19689.1| 152|Homo sapiens mitogen-activated protein... 61 2e-08
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 61 2e-08
M55268-1|AAA51548.1| 350|Homo sapiens casein kinase II alpha' s... 61 2e-08
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 61 2e-08
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 61 2e-08
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 61 2e-08
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 61 2e-08
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 61 2e-08
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 61 2e-08
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 61 2e-08
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 61 2e-08
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 61 2e-08
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 61 2e-08
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 61 2e-08
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 61 2e-08
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 61 2e-08
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 61 2e-08
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 61 2e-08
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 61 2e-08
BC008812-1|AAH08812.1| 350|Homo sapiens casein kinase 2, alpha ... 61 2e-08
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 61 2e-08
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 61 2e-08
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 61 2e-08
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 61 2e-08
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 61 2e-08
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 61 2e-08
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 61 2e-08
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 61 2e-08
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 61 2e-08
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 61 2e-08
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 61 2e-08
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 61 2e-08
>U48736-1|AAB03268.1| 496|Homo sapiens serine/threonine-protein
kinase PRP4h protein.
Length = 496
Score = 471 bits (1160), Expect = e-132
Identities = 253/462 (54%), Positives = 303/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 47 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 106
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 107 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 162
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 163 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 222
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 223 EFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 282
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYLVSR
Sbjct: 283 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSR 342
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 343 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 402
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 403 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 454
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 455 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 496
>BC009844-1|AAH09844.1| 496|Homo sapiens PRPF4B protein protein.
Length = 496
Score = 471 bits (1160), Expect = e-132
Identities = 253/462 (54%), Positives = 303/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 47 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 106
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 107 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 162
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 163 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 222
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 223 EFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 282
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYLVSR
Sbjct: 283 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSR 342
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 343 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 402
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 403 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 454
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 455 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 496
>AY029347-1|AAK38155.1| 1007|Homo sapiens serine/threonine-protein
kinase protein.
Length = 1007
Score = 471 bits (1160), Expect = e-132
Identities = 253/462 (54%), Positives = 303/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 558 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 617
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 618 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 673
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 674 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 733
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 734 EFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 793
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYLVSR
Sbjct: 794 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSR 853
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 854 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 913
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 914 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 965
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 966 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 1007
>AL138831-3|CAI20480.1| 1007|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog B (yeast) protein.
Length = 1007
Score = 471 bits (1160), Expect = e-132
Identities = 253/462 (54%), Positives = 303/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 558 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 617
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 618 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 673
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 674 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 733
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 734 EFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 793
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYLVSR
Sbjct: 794 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSR 853
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 854 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 913
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 914 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 965
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 966 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 1007
>AL033383-1|CAI42121.1| 1007|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog B (yeast) protein.
Length = 1007
Score = 471 bits (1160), Expect = e-132
Identities = 253/462 (54%), Positives = 303/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 558 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 617
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 618 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 673
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 674 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 733
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 734 EFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 793
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYLVSR
Sbjct: 794 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSR 853
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 854 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 913
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 914 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 965
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 966 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 1007
>AF283465-1|AAM19101.1| 1007|Homo sapiens PRP4 kinase protein.
Length = 1007
Score = 471 bits (1160), Expect = e-132
Identities = 253/462 (54%), Positives = 303/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 558 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 617
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 618 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 673
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 674 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 733
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 734 EFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 793
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYLVSR
Sbjct: 794 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSR 853
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 854 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 913
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 914 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 965
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 966 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 1007
>AB011108-1|BAA25462.1| 1028|Homo sapiens KIAA0536 protein protein.
Length = 1028
Score = 471 bits (1160), Expect = e-132
Identities = 253/462 (54%), Positives = 303/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 579 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 638
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 639 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 694
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 695 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 754
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 755 EFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 814
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYLVSR
Sbjct: 815 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSR 874
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 875 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 934
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 935 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 986
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 987 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 1028
>BC034969-1|AAH34969.1| 1007|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog B (yeast) protein.
Length = 1007
Score = 469 bits (1155), Expect = e-131
Identities = 252/462 (54%), Positives = 302/462 (65%), Gaps = 19/462 (4%)
Query: 506 ERTQNATASPFSPQSQ---RSVSPTS--KNKSHDHKEKNKEERKHIRTETRSETLIKKIE 560
+ + + P SPQS RS SP + + D KE +E +++ + +E
Sbjct: 558 DSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 617
Query: 561 -NESKSTIKLQKSNKDSEWD-MFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEG 618
N S KL + +E D MFA FDS G K ENP+L DNW DAEG
Sbjct: 618 QNNGSSQKKLLAPDMFTESDDMFAAY--FDSARLRAAGIGKD--FKENPNLRDNWTDAEG 673
Query: 619 YYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLREL 678
YYRV IGE LD RYNVYGYTGQGVFSNVVRARD AR+N +VAVKIIRNNE+M KTGL+EL
Sbjct: 674 YYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKEL 733
Query: 679 EILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVR 738
E LK+LNDADP+D +V EPLSMNLREVLKKYGK+ G+HIKAVR
Sbjct: 734 EFLKKLNDADPDDKFHCLRLLRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVR 793
Query: 739 SYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSR 798
SY+QQ+ I+HADIKPDNILVNE+K LKLCDFG+AS V DN+ITPYL SR
Sbjct: 794 SYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLFSR 853
Query: 799 FYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXX 858
FYRAPEII+G YD+GIDMWS CT+YEL TGKI+F GK+NN MLK MDL
Sbjct: 854 FYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMI 913
Query: 859 XXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRL 918
FK+QHFD N NF+Y E+DK+TER EKV ++S+I PT+DL +L RL
Sbjct: 914 RKGVFKDQHFDQNLNFMYIEVDKVTER-------EKVTVMSTINPTKDLLADLI-GCQRL 965
Query: 919 PLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQEKL 960
P + KK+ QLKDLL+++LMLDPAKR S+N L H FIQEK+
Sbjct: 966 PEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI 1007
>U58496-1|AAC50939.1| 763|Homo sapiens hp86 protein.
Length = 763
Score = 138 bits (335), Expect = 7e-32
Identities = 80/248 (32%), Positives = 126/248 (50%), Gaps = 6/248 (2%)
Query: 605 ENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII 664
E D +DD Y V+ GE +RY + G+G F VV+A D+ VA+KII
Sbjct: 132 ERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEW-VAIKII 190
Query: 665 RNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLK 724
+N + E+ +L+ +N D E +V E LS NL ++L+
Sbjct: 191 KNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLR 250
Query: 725 KYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKLNLKLCDFG 781
G+ + R + QQM I+H D+KP+NIL+ N + +K+ DFG
Sbjct: 251 NTNFR-GVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFG 309
Query: 782 AASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNE 841
++ Q+ I Y+ SRFYR+PE++LG+PYD IDMWS C + E+ TG+ +FSG + +
Sbjct: 310 SSCQL-GQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVD 368
Query: 842 MLKYFMDL 849
+ +++
Sbjct: 369 QMNKIVEV 376
>U52373-1|AAB18639.1| 763|Homo sapiens MNB protein.
Length = 763
Score = 138 bits (335), Expect = 7e-32
Identities = 80/248 (32%), Positives = 126/248 (50%), Gaps = 6/248 (2%)
Query: 605 ENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII 664
E D +DD Y V+ GE +RY + G+G F VV+A D+ VA+KII
Sbjct: 132 ERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEW-VAIKII 190
Query: 665 RNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLK 724
+N + E+ +L+ +N D E +V E LS NL ++L+
Sbjct: 191 KNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLR 250
Query: 725 KYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKLNLKLCDFG 781
G+ + R + QQM I+H D+KP+NIL+ N + +K+ DFG
Sbjct: 251 NTNFR-GVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFG 309
Query: 782 AASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNE 841
++ Q+ I Y+ SRFYR+PE++LG+PYD IDMWS C + E+ TG+ +FSG + +
Sbjct: 310 SSCQL-GQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVD 368
Query: 842 MLKYFMDL 849
+ +++
Sbjct: 369 QMNKIVEV 376
>D86550-1|BAA13110.1| 754|Homo sapiens serine/threonine protein
kinase protein.
Length = 754
Score = 138 bits (335), Expect = 7e-32
Identities = 80/248 (32%), Positives = 126/248 (50%), Gaps = 6/248 (2%)
Query: 605 ENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII 664
E D +DD Y V+ GE +RY + G+G F VV+A D+ VA+KII
Sbjct: 123 ERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEW-VAIKII 181
Query: 665 RNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLK 724
+N + E+ +L+ +N D E +V E LS NL ++L+
Sbjct: 182 KNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLR 241
Query: 725 KYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKLNLKLCDFG 781
G+ + R + QQM I+H D+KP+NIL+ N + +K+ DFG
Sbjct: 242 NTNFR-GVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFG 300
Query: 782 AASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNE 841
++ Q+ I Y+ SRFYR+PE++LG+PYD IDMWS C + E+ TG+ +FSG + +
Sbjct: 301 SSCQL-GQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVD 359
Query: 842 MLKYFMDL 849
+ +++
Sbjct: 360 QMNKIVEV 367
>D85759-1|BAA12866.1| 754|Homo sapiens MNB protein kinase protein.
Length = 754
Score = 138 bits (335), Expect = 7e-32
Identities = 80/248 (32%), Positives = 126/248 (50%), Gaps = 6/248 (2%)
Query: 605 ENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII 664
E D +DD Y V+ GE +RY + G+G F VV+A D+ VA+KII
Sbjct: 123 ERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEW-VAIKII 181
Query: 665 RNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLK 724
+N + E+ +L+ +N D E +V E LS NL ++L+
Sbjct: 182 KNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLR 241
Query: 725 KYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKLNLKLCDFG 781
G+ + R + QQM I+H D+KP+NIL+ N + +K+ DFG
Sbjct: 242 NTNFR-GVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFG 300
Query: 782 AASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNE 841
++ Q+ I Y+ SRFYR+PE++LG+PYD IDMWS C + E+ TG+ +FSG + +
Sbjct: 301 SSCQL-GQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVD 359
Query: 842 MLKYFMDL 849
+ +++
Sbjct: 360 QMNKIVEV 367
>AF108830-1|AAD31169.1| 584|Homo sapiens serine-threonine protein
kinase protein.
Length = 584
Score = 138 bits (335), Expect = 7e-32
Identities = 80/248 (32%), Positives = 126/248 (50%), Gaps = 6/248 (2%)
Query: 605 ENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII 664
E D +DD Y V+ GE +RY + G+G F VV+A D+ VA+KII
Sbjct: 132 ERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEW-VAIKII 190
Query: 665 RNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLK 724
+N + E+ +L+ +N D E +V E LS NL ++L+
Sbjct: 191 KNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLR 250
Query: 725 KYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKLNLKLCDFG 781
G+ + R + QQM I+H D+KP+NIL+ N + +K+ DFG
Sbjct: 251 NTNFR-GVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFG 309
Query: 782 AASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNE 841
++ Q+ I Y+ SRFYR+PE++LG+PYD IDMWS C + E+ TG+ +FSG + +
Sbjct: 310 SSCQL-GQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVD 368
Query: 842 MLKYFMDL 849
+ +++
Sbjct: 369 QMNKIVEV 376
>BC031244-1|AAH31244.1| 520|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 4 protein.
Length = 520
Score = 138 bits (333), Expect = 1e-31
Identities = 85/252 (33%), Positives = 128/252 (50%), Gaps = 5/252 (1%)
Query: 599 KTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTD 658
K A E S T ++DD G+Y + + + RY V G+G F V + D ++N
Sbjct: 72 KLDTAPEKFSKT-SFDDEHGFYLKVLHDHIAYRYEVLETIGKGSFGQVAKCLDH-KNNEL 129
Query: 659 VAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMN 718
VA+KIIRN + H+ L EL+IL+ L D ++ + E L +N
Sbjct: 130 VALKIIRNKKRFHQQALMELKILEALRKKDKDNTYNVVHMKDFFYFRNHFCITFELLGIN 189
Query: 719 LREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNI-LVNENKLNLKL 777
L E++K G + VR +T + I+H D+KP+NI L + + ++K+
Sbjct: 190 LYELMKN-NNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQKGQASVKV 248
Query: 778 CDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
DFG+ S ++ Y+ SRFYR+PE+ILG PYD IDMWS C EL TG +F G+
Sbjct: 249 IDFGS-SCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAELYTGYPLFPGE 307
Query: 838 SNNEMLKYFMDL 849
+ E L M++
Sbjct: 308 NEVEQLACIMEV 319
>AF326592-1|AAL37371.1| 1171|Homo sapiens homeodomain interacting
protein kinase 2 protein.
Length = 1171
Score = 138 bits (333), Expect = 1e-31
Identities = 105/380 (27%), Positives = 171/380 (45%), Gaps = 19/380 (5%)
Query: 590 VDTPTTGDSKTKLATENPSLTDNWDDAEGYYRVRIGETL---DNRYNVYGYTGQGVFSNV 646
+ +G + T + ++ ++EG Y++ E L N Y V + G+G F V
Sbjct: 154 IQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQV 213
Query: 647 VRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXX 706
V+ + +N VA+KI++N+ + G E+ IL RL+ +D
Sbjct: 214 VKCWKRG-TNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNH 272
Query: 707 XXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNI 766
+V E L NL + LK+ K S + +K +R QQ+ G++HAD+KP+NI
Sbjct: 273 TC-LVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENI 330
Query: 767 LV---NENKLNLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACT 823
++ + +K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS C
Sbjct: 331 MLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCV 390
Query: 824 IYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLY------H 877
I EL G ++ G S + ++Y + F+ + + Y
Sbjct: 391 IAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKT 450
Query: 878 ELDKITERNFTLCQQEKVVIISSIKPTR-DLQTELAPPHHRLPLPEAKKISQLKDLLERM 936
D E + K + I + ++ T+L L E + DLL++M
Sbjct: 451 PDDHEAETGIKSKEARKYIFICLDDMAQVNMTTDLEGSD---MLVEKADRREFIDLLKKM 507
Query: 937 LMLDPAKRASVNHCLAHPFI 956
L +D KR + L HPF+
Sbjct: 508 LTIDADKRITPIETLNHPFV 527
>AF263541-1|AAF91393.1| 541|Homo sapiens protein kinase DYRK4
protein.
Length = 541
Score = 138 bits (333), Expect = 1e-31
Identities = 85/252 (33%), Positives = 128/252 (50%), Gaps = 5/252 (1%)
Query: 599 KTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTD 658
K A E S T ++DD G+Y + + + RY V G+G F V + D ++N
Sbjct: 94 KLDTAPEKFSKT-SFDDEHGFYLKVLHDHIAYRYEVLETIGKGSFGQVAKCLDH-KNNEL 151
Query: 659 VAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMN 718
VA+KIIRN + H+ L EL+IL+ L D ++ + E L +N
Sbjct: 152 VALKIIRNKKRFHQQALMELKILEALRKKDKDNTYNVVHMKDFFYFRNHFCITFELLGIN 211
Query: 719 LREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNI-LVNENKLNLKL 777
L E++K G + VR +T + I+H D+KP+NI L + + ++K+
Sbjct: 212 LYELMKN-NNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQKGQASVKV 270
Query: 778 CDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
DFG+ S ++ Y+ SRFYR+PE+ILG PYD IDMWS C EL TG +F G+
Sbjct: 271 IDFGS-SCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAELYTGYPLFPGE 329
Query: 838 SNNEMLKYFMDL 849
+ E L M++
Sbjct: 330 NEVEQLACIMEV 341
>AL122015-2|CAJ55828.1| 1194|Homo sapiens homeodomain interacting
protein kinase 3 protein.
Length = 1194
Score = 136 bits (330), Expect = 3e-31
Identities = 101/369 (27%), Positives = 165/369 (44%), Gaps = 15/369 (4%)
Query: 602 LATENPSLTDNWDDAEGYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTD 658
+ T N EG Y++ E L N Y V + G+G F VV+ + +N
Sbjct: 164 VVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRG-TNEI 222
Query: 659 VAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMN 718
VA+KI++N+ + G E+ IL RL+ + D +V E L N
Sbjct: 223 VAIKILKNHPSYARQGQIEVSILARLS-TENADEYNFVRAYECFQHRNHTCLVFEMLEQN 281
Query: 719 LREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNE---NKLNL 775
L + LK+ K S + +K +R QQ+ G++HAD+KP+NI++ + +
Sbjct: 282 LYDFLKQ-NKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRV 340
Query: 776 KLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFS 835
K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS C I EL G ++
Sbjct: 341 KVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYP 400
Query: 836 GKSNNEMLKYFMDL-----XXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLC 890
G + ++Y F ++ ++ + L++
Sbjct: 401 GALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKS 460
Query: 891 QQEKVVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHC 950
++ + I +S+ + T + L L E + LL++ML++D R +
Sbjct: 461 KEARKYIFNSLDDVAHVNTVMDLEGSDL-LAEKADRREFVSLLKKMLLIDADLRITPAET 519
Query: 951 LAHPFIQEK 959
L HPF+ K
Sbjct: 520 LNHPFVNMK 528
>AL122015-1|CAC13164.1| 1215|Homo sapiens homeodomain interacting
protein kinase 3 protein.
Length = 1215
Score = 136 bits (330), Expect = 3e-31
Identities = 101/369 (27%), Positives = 165/369 (44%), Gaps = 15/369 (4%)
Query: 602 LATENPSLTDNWDDAEGYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTD 658
+ T N EG Y++ E L N Y V + G+G F VV+ + +N
Sbjct: 164 VVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRG-TNEI 222
Query: 659 VAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMN 718
VA+KI++N+ + G E+ IL RL+ + D +V E L N
Sbjct: 223 VAIKILKNHPSYARQGQIEVSILARLS-TENADEYNFVRAYECFQHRNHTCLVFEMLEQN 281
Query: 719 LREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNE---NKLNL 775
L + LK+ K S + +K +R QQ+ G++HAD+KP+NI++ + +
Sbjct: 282 LYDFLKQ-NKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRV 340
Query: 776 KLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFS 835
K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS C I EL G ++
Sbjct: 341 KVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYP 400
Query: 836 GKSNNEMLKYFMDL-----XXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLC 890
G + ++Y F ++ ++ + L++
Sbjct: 401 GALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKS 460
Query: 891 QQEKVVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHC 950
++ + I +S+ + T + L L E + LL++ML++D R +
Sbjct: 461 KEARKYIFNSLDDVAHVNTVMDLEGSDL-LAEKADRREFVSLLKKMLLIDADLRITPAET 519
Query: 951 LAHPFIQEK 959
L HPF+ K
Sbjct: 520 LNHPFVNMK 528
>AF305239-1|AAG25990.1| 1194|Homo sapiens Fas-interacting
serine/threonine kinase 3 protein.
Length = 1194
Score = 136 bits (330), Expect = 3e-31
Identities = 101/369 (27%), Positives = 165/369 (44%), Gaps = 15/369 (4%)
Query: 602 LATENPSLTDNWDDAEGYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTD 658
+ T N EG Y++ E L N Y V + G+G F VV+ + +N
Sbjct: 164 VVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRG-TNEI 222
Query: 659 VAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMN 718
VA+KI++N+ + G E+ IL RL+ + D +V E L N
Sbjct: 223 VAIKILKNHPSYARQGQIEVSILARLS-TENADEYNFVRAYECFQHRNHTCLVFEMLEQN 281
Query: 719 LREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNE---NKLNL 775
L + LK+ K S + +K +R QQ+ G++HAD+KP+NI++ + +
Sbjct: 282 LYDFLKQ-NKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRV 340
Query: 776 KLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFS 835
K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS C I EL G ++
Sbjct: 341 KVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYP 400
Query: 836 GKSNNEMLKYFMDL-----XXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLC 890
G + ++Y F ++ ++ + L++
Sbjct: 401 GALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKS 460
Query: 891 QQEKVVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHC 950
++ + I +S+ + T + L L E + LL++ML++D R +
Sbjct: 461 KEARKYIFNSLDDVAHVNTVMDLEGSDL-LAEKADRREFVSLLKKMLLIDADLRITPAET 519
Query: 951 LAHPFIQEK 959
L HPF+ K
Sbjct: 520 LNHPFVNMK 528
>AF004849-1|AAC64294.1| 1215|Homo sapiens PKY protein kinase
protein.
Length = 1215
Score = 136 bits (330), Expect = 3e-31
Identities = 101/369 (27%), Positives = 165/369 (44%), Gaps = 15/369 (4%)
Query: 602 LATENPSLTDNWDDAEGYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTD 658
+ T N EG Y++ E L N Y V + G+G F VV+ + +N
Sbjct: 164 VVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRG-TNEI 222
Query: 659 VAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMN 718
VA+KI++N+ + G E+ IL RL+ + D +V E L N
Sbjct: 223 VAIKILKNHPSYARQGQIEVSILARLS-TENADEYNFVRAYECFQHRNHTCLVFEMLEQN 281
Query: 719 LREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNE---NKLNL 775
L + LK+ K S + +K +R QQ+ G++HAD+KP+NI++ + +
Sbjct: 282 LYDFLKQ-NKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRV 340
Query: 776 KLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFS 835
K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS C I EL G ++
Sbjct: 341 KVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYP 400
Query: 836 GKSNNEMLKYFMDL-----XXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLC 890
G + ++Y F ++ ++ + L++
Sbjct: 401 GALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKS 460
Query: 891 QQEKVVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHC 950
++ + I +S+ + T + L L E + LL++ML++D R +
Sbjct: 461 KEARKYIFNSLDDVAHVNTVMDLEGSDL-LAEKADRREFVSLLKKMLLIDADLRITPAET 519
Query: 951 LAHPFIQEK 959
L HPF+ K
Sbjct: 520 LNHPFVNMK 528
>Y17999-3|CAA76990.1| 589|Homo sapiens Dyrk1B protein kinase
protein.
Length = 589
Score = 136 bits (329), Expect = 4e-31
Identities = 84/256 (32%), Positives = 125/256 (48%), Gaps = 8/256 (3%)
Query: 597 DSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSN 656
DS K E L +DD Y VR GE RY + G+G F VV+A D
Sbjct: 78 DSSNK--KEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQE 135
Query: 657 TDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLS 716
VA+KII+N + EL +L+ +N D E +V E LS
Sbjct: 136 L-VAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLS 194
Query: 717 MNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKL 773
NL ++L+ G+ + R QQ+ I+H D+KP+NIL+ N +
Sbjct: 195 YNLYDLLRNTHFR-GVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS 253
Query: 774 NLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIM 833
+K+ DFG++ Q+ I Y+ SRFYR+PE++LG PYD IDMWS C + E+ TG+ +
Sbjct: 254 AIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPL 312
Query: 834 FSGKSNNEMLKYFMDL 849
FSG + + + +++
Sbjct: 313 FSGSNEVDQMNRIVEV 328
>Y17999-2|CAA76989.1| 601|Homo sapiens Dyrk1B protein kinase
protein.
Length = 601
Score = 136 bits (329), Expect = 4e-31
Identities = 84/256 (32%), Positives = 125/256 (48%), Gaps = 8/256 (3%)
Query: 597 DSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSN 656
DS K E L +DD Y VR GE RY + G+G F VV+A D
Sbjct: 78 DSSNK--KEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQE 135
Query: 657 TDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLS 716
VA+KII+N + EL +L+ +N D E +V E LS
Sbjct: 136 L-VAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLS 194
Query: 717 MNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKL 773
NL ++L+ G+ + R QQ+ I+H D+KP+NIL+ N +
Sbjct: 195 YNLYDLLRNTHFR-GVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS 253
Query: 774 NLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIM 833
+K+ DFG++ Q+ I Y+ SRFYR+PE++LG PYD IDMWS C + E+ TG+ +
Sbjct: 254 AIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPL 312
Query: 834 FSGKSNNEMLKYFMDL 849
FSG + + + +++
Sbjct: 313 FSGSNEVDQMNRIVEV 328
>Y17999-1|CAA76991.1| 629|Homo sapiens Dyrk1B protein kinase
protein.
Length = 629
Score = 136 bits (329), Expect = 4e-31
Identities = 84/256 (32%), Positives = 125/256 (48%), Gaps = 8/256 (3%)
Query: 597 DSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSN 656
DS K E L +DD Y VR GE RY + G+G F VV+A D
Sbjct: 78 DSSNK--KEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQE 135
Query: 657 TDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLS 716
VA+KII+N + EL +L+ +N D E +V E LS
Sbjct: 136 L-VAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLS 194
Query: 717 MNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKL 773
NL ++L+ G+ + R QQ+ I+H D+KP+NIL+ N +
Sbjct: 195 YNLYDLLRNTHFR-GVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS 253
Query: 774 NLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIM 833
+K+ DFG++ Q+ I Y+ SRFYR+PE++LG PYD IDMWS C + E+ TG+ +
Sbjct: 254 AIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPL 312
Query: 834 FSGKSNNEMLKYFMDL 849
FSG + + + +++
Sbjct: 313 FSGSNEVDQMNRIVEV 328
>BC025291-1|AAH25291.1| 629|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 1B
protein.
Length = 629
Score = 136 bits (329), Expect = 4e-31
Identities = 84/256 (32%), Positives = 125/256 (48%), Gaps = 8/256 (3%)
Query: 597 DSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSN 656
DS K E L +DD Y VR GE RY + G+G F VV+A D
Sbjct: 78 DSSNK--KEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQE 135
Query: 657 TDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLS 716
VA+KII+N + EL +L+ +N D E +V E LS
Sbjct: 136 L-VAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLS 194
Query: 717 MNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKL 773
NL ++L+ G+ + R QQ+ I+H D+KP+NIL+ N +
Sbjct: 195 YNLYDLLRNTHFR-GVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS 253
Query: 774 NLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIM 833
+K+ DFG++ Q+ I Y+ SRFYR+PE++LG PYD IDMWS C + E+ TG+ +
Sbjct: 254 AIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPL 312
Query: 834 FSGKSNNEMLKYFMDL 849
FSG + + + +++
Sbjct: 313 FSGSNEVDQMNRIVEV 328
>BC018751-1|AAH18751.1| 629|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 1B
protein.
Length = 629
Score = 136 bits (329), Expect = 4e-31
Identities = 84/256 (32%), Positives = 125/256 (48%), Gaps = 8/256 (3%)
Query: 597 DSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSN 656
DS K E L +DD Y VR GE RY + G+G F VV+A D
Sbjct: 78 DSSNK--KEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQE 135
Query: 657 TDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLS 716
VA+KII+N + EL +L+ +N D E +V E LS
Sbjct: 136 L-VAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLS 194
Query: 717 MNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKL 773
NL ++L+ G+ + R QQ+ I+H D+KP+NIL+ N +
Sbjct: 195 YNLYDLLRNTHFR-GVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS 253
Query: 774 NLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIM 833
+K+ DFG++ Q+ I Y+ SRFYR+PE++LG PYD IDMWS C + E+ TG+ +
Sbjct: 254 AIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPL 312
Query: 834 FSGKSNNEMLKYFMDL 849
FSG + + + +++
Sbjct: 313 FSGSNEVDQMNRIVEV 328
>AF205861-1|AAF15893.1| 629|Homo sapiens protein kinase MIRK
protein.
Length = 629
Score = 136 bits (329), Expect = 4e-31
Identities = 84/256 (32%), Positives = 125/256 (48%), Gaps = 8/256 (3%)
Query: 597 DSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSN 656
DS K E L +DD Y VR GE RY + G+G F VV+A D
Sbjct: 78 DSSNK--KEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQE 135
Query: 657 TDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLS 716
VA+KII+N + EL +L+ +N D E +V E LS
Sbjct: 136 L-VAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLS 194
Query: 717 MNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNILV-NENKL 773
NL ++L+ G+ + R QQ+ I+H D+KP+NIL+ N +
Sbjct: 195 YNLYDLLRNTHFR-GVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS 253
Query: 774 NLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIM 833
+K+ DFG++ Q+ I Y+ SRFYR+PE++LG PYD IDMWS C + E+ TG+ +
Sbjct: 254 AIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPL 312
Query: 834 FSGKSNNEMLKYFMDL 849
FSG + + + +++
Sbjct: 313 FSGSNEVDQMNRIVEV 328
>AF208291-1|AAG41236.1| 1198|Homo sapiens protein kinase HIPK2
protein.
Length = 1198
Score = 136 bits (328), Expect = 5e-31
Identities = 100/378 (26%), Positives = 169/378 (44%), Gaps = 15/378 (3%)
Query: 590 VDTPTTGDSKTKLATENPSLTDNWDDAEGYYRVRIGETL---DNRYNVYGYTGQGVFSNV 646
+ +G + T + ++ ++EG Y++ E L N Y V + G+G F V
Sbjct: 154 IQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQV 213
Query: 647 VRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXX 706
V+ + +N VA+KI++N + G E+ IL RL+ +D
Sbjct: 214 VKCWKRG-TNEIVAIKILKNRPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNH 272
Query: 707 XXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNI 766
+V E L NL + LK+ K S + +K +R QQ+ G++HAD+KP+NI
Sbjct: 273 TC-LVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENI 330
Query: 767 LV---NENKLNLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACT 823
++ + +K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS C
Sbjct: 331 MLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCV 390
Query: 824 IYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLY-----HE 878
I EL G ++ G S + ++Y + F+ + + Y
Sbjct: 391 IAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKT 450
Query: 879 LDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLM 938
D ++ + I + + + + + +A + + DLL++ML
Sbjct: 451 PDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADR-REFIDLLKKMLT 509
Query: 939 LDPAKRASVNHCLAHPFI 956
+D KR + L HPF+
Sbjct: 510 IDADKRITPIETLNHPFV 527
>AF207702-1|AAG35710.1| 911|Homo sapiens homeodomain-interacting
protein kinase 2 protein.
Length = 911
Score = 135 bits (327), Expect = 6e-31
Identities = 100/378 (26%), Positives = 170/378 (44%), Gaps = 15/378 (3%)
Query: 590 VDTPTTGDSKTKLATENPSLTDNWDDAEGYYRVRIGETL---DNRYNVYGYTGQGVFSNV 646
+ +G + T + ++ ++EG Y++ E L N Y V + G+G F V
Sbjct: 147 IQNNASGATVATATTFTATSKNSGSNSEGDYQLSQHEVLCSMTNTYEVSEFLGRGTFGQV 206
Query: 647 VRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXX 706
V+ + +N VA+KI++N+ + G E+ IL RL+ +D
Sbjct: 207 VKCWKRG-TNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNH 265
Query: 707 XXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNI 766
+V E L NL + LK+ K S + +K +R QQ+ G++HAD+KP+NI
Sbjct: 266 TC-LVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENI 323
Query: 767 LV---NENKLNLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACT 823
++ + +K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS C
Sbjct: 324 MLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCV 383
Query: 824 IYELSTGKIMFSGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLY-----HE 878
I EL G ++ G S + ++Y + F+ + + Y
Sbjct: 384 IAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKT 443
Query: 879 LDKITERNFTLCQQEKVVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLM 938
D ++ + I + + + + + +A + + DLL++ML
Sbjct: 444 PDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADR-REFIDLLKKMLT 502
Query: 939 LDPAKRASVNHCLAHPFI 956
+D KR + L HPF+
Sbjct: 503 IDADKRITPIETLNHPFV 520
>Y13493-1|CAA73885.1| 528|Homo sapiens protein kinase Dyrk2
protein.
Length = 528
Score = 133 bits (322), Expect = 2e-30
Identities = 78/238 (32%), Positives = 118/238 (49%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DD +G Y + + RY V G+G F VV+A D + + VA+K++RN + H+
Sbjct: 130 YDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDH-KVHQHVALKMVRNEKRFHR 188
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D ++ M E LSMNL E++KK K G
Sbjct: 189 QAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKK-NKFQGF 247
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
+ VR + + I+H D+KP+NIL+ + + +K+ DFG+ S +
Sbjct: 248 SLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGS-SCYEHQRV 306
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPE+ILG Y IDMWS C + EL TG + G+ + L ++L
Sbjct: 307 YTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIEL 364
>BC006375-1|AAH06375.1| 601|Homo sapiens DYRK2 protein protein.
Length = 601
Score = 133 bits (322), Expect = 2e-30
Identities = 78/238 (32%), Positives = 118/238 (49%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DD +G Y + + RY V G+G F VV+A D + + VA+K++RN + H+
Sbjct: 203 YDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDH-KVHQHVALKMVRNEKRFHR 261
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D ++ M E LSMNL E++KK K G
Sbjct: 262 QAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKK-NKFQGF 320
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
+ VR + + I+H D+KP+NIL+ + + +K+ DFG+ S +
Sbjct: 321 SLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGS-SCYEHQRV 379
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPE+ILG Y IDMWS C + EL TG + G+ + L ++L
Sbjct: 380 YTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIEL 437
>BC005809-1|AAH05809.1| 528|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 2 protein.
Length = 528
Score = 133 bits (322), Expect = 2e-30
Identities = 78/238 (32%), Positives = 118/238 (49%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DD +G Y + + RY V G+G F VV+A D + + VA+K++RN + H+
Sbjct: 130 YDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDH-KVHQHVALKMVRNEKRFHR 188
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D ++ M E LSMNL E++KK K G
Sbjct: 189 QAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKK-NKFQGF 247
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
+ VR + + I+H D+KP+NIL+ + + +K+ DFG+ S +
Sbjct: 248 SLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGS-SCYEHQRV 306
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPE+ILG Y IDMWS C + EL TG + G+ + L ++L
Sbjct: 307 YTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIEL 364
>AY590695-1|AAT06103.1| 588|Homo sapiens dual-specificity
tyrosine-phosphorylation regulated kinase 3 long isoform
protein.
Length = 588
Score = 133 bits (322), Expect = 2e-30
Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 190 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 248
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 249 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 307
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ VR + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 308 SVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 366
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 367 YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMEL 424
>AL591846-9|CAI13541.1| 568|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 3 protein.
Length = 568
Score = 133 bits (322), Expect = 2e-30
Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 170 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 228
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 229 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 287
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ VR + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 288 SVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 346
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 347 YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMEL 404
>AL591846-7|CAI13539.1| 588|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 3 protein.
Length = 588
Score = 133 bits (322), Expect = 2e-30
Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 190 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 248
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 249 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 307
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ VR + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 308 SVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 366
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 367 YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMEL 424
>AF327561-1|AAK16443.1| 568|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 5 protein.
Length = 568
Score = 133 bits (322), Expect = 2e-30
Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 170 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 228
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 229 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 287
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ VR + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 288 SVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 346
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 347 YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMEL 404
>AF186774-1|AAG17029.1| 568|Homo sapiens regulatory erythroid
kinase short form protein.
Length = 568
Score = 133 bits (322), Expect = 2e-30
Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 170 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 228
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 229 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 287
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ VR + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 288 SVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 346
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 347 YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMEL 404
>AF186773-1|AAG17028.1| 588|Homo sapiens regulatory erythroid
kinase long form protein.
Length = 588
Score = 133 bits (322), Expect = 2e-30
Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 190 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 248
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 249 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 307
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ VR + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 308 SVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 366
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 367 YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMEL 424
>Y12735-1|CAA73266.2| 588|Homo sapiens Dyrk3 protein protein.
Length = 588
Score = 133 bits (321), Expect = 3e-30
Identities = 80/238 (33%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 190 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 248
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 249 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 307
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ VR + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 308 SVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 366
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 367 YTYIQSRFYRAPEIILGSRYSTPIDIWSFRCILAELLTGQPLFPGEDEGDQLACMMEL 424
>BC015501-1|AAH15501.1| 568|Homo sapiens dual-specificity
tyrosine-(Y)-phosphorylation regulated kinase 3 protein.
Length = 568
Score = 131 bits (317), Expect = 1e-29
Identities = 79/238 (33%), Positives = 118/238 (49%), Gaps = 4/238 (1%)
Query: 613 WDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHK 672
+DDA+G Y + L RY V G+G F V R D + VA+K++RN + H+
Sbjct: 170 YDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDH-KLRQYVALKMVRNEKRFHR 228
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
E+ IL+ L D M E LS++L E++KK K G
Sbjct: 229 QAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NKFQGF 287
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNEN-KLNLKLCDFGAASQVTDNEI 791
++ V + Q + I+H D+KP+NIL+ + + + K+ DFG+ S ++
Sbjct: 288 SVQLVHKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGS-SCFEYQKL 346
Query: 792 TPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ SRFYRAPEIILG Y ID+WS C + EL TG+ +F G+ + L M+L
Sbjct: 347 YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMEL 404
>BC033012-1|AAH33012.1| 1075|Homo sapiens homeodomain interacting
protein kinase 1 protein.
Length = 1075
Score = 129 bits (312), Expect = 4e-29
Identities = 74/222 (33%), Positives = 117/222 (52%), Gaps = 6/222 (2%)
Query: 627 TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLND 686
++ N Y V + G+G F V + ++ VA+KI++N+ + G E+ IL RL+
Sbjct: 185 SMTNSYEVLEFLGRGTFGQVAKCWKRSTKEI-VAIKILKNHPSYARQGQIEVSILSRLS- 242
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
++ D +V E L NL + LK+ K S + +K +R QQ+
Sbjct: 243 SENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPILQQVAT 301
Query: 747 XXXXXXXTGIVHADIKPDNILVNE---NKLNLKLCDFGAASQVTDNEITPYLVSRFYRAP 803
G++HAD+KP+NI++ + +K+ DFG+AS V+ + YL SR+YRAP
Sbjct: 302 ALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAP 361
Query: 804 EIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
EIILG+P+ IDMWS C I EL G ++ G S + ++Y
Sbjct: 362 EIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRY 403
>AL731797-3|CAI22793.1| 1210|Homo sapiens homeodomain interacting
protein kinase 1 protein.
Length = 1210
Score = 129 bits (312), Expect = 4e-29
Identities = 74/222 (33%), Positives = 117/222 (52%), Gaps = 6/222 (2%)
Query: 627 TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLND 686
++ N Y V + G+G F V + ++ VA+KI++N+ + G E+ IL RL+
Sbjct: 185 SMTNSYEVLEFLGRGTFGQVAKCWKRSTKEI-VAIKILKNHPSYARQGQIEVSILSRLS- 242
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
++ D +V E L NL + LK+ K S + +K +R QQ+
Sbjct: 243 SENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPILQQVAT 301
Query: 747 XXXXXXXTGIVHADIKPDNILVNE---NKLNLKLCDFGAASQVTDNEITPYLVSRFYRAP 803
G++HAD+KP+NI++ + +K+ DFG+AS V+ + YL SR+YRAP
Sbjct: 302 ALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAP 361
Query: 804 EIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
EIILG+P+ IDMWS C I EL G ++ G S + ++Y
Sbjct: 362 EIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRY 403
>AL731797-2|CAI22794.1| 1165|Homo sapiens homeodomain interacting
protein kinase 1 protein.
Length = 1165
Score = 129 bits (312), Expect = 4e-29
Identities = 74/222 (33%), Positives = 117/222 (52%), Gaps = 6/222 (2%)
Query: 627 TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLND 686
++ N Y V + G+G F V + ++ VA+KI++N+ + G E+ IL RL+
Sbjct: 185 SMTNSYEVLEFLGRGTFGQVAKCWKRSTKEI-VAIKILKNHPSYARQGQIEVSILSRLS- 242
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
++ D +V E L NL + LK+ K S + +K +R QQ+
Sbjct: 243 SENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPILQQVAT 301
Query: 747 XXXXXXXTGIVHADIKPDNILVNE---NKLNLKLCDFGAASQVTDNEITPYLVSRFYRAP 803
G++HAD+KP+NI++ + +K+ DFG+AS V+ + YL SR+YRAP
Sbjct: 302 ALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAP 361
Query: 804 EIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
EIILG+P+ IDMWS C I EL G ++ G S + ++Y
Sbjct: 362 EIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRY 403
>AL731797-1|CAI22792.1| 1075|Homo sapiens homeodomain interacting
protein kinase 1 protein.
Length = 1075
Score = 129 bits (312), Expect = 4e-29
Identities = 74/222 (33%), Positives = 117/222 (52%), Gaps = 6/222 (2%)
Query: 627 TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLND 686
++ N Y V + G+G F V + ++ VA+KI++N+ + G E+ IL RL+
Sbjct: 185 SMTNSYEVLEFLGRGTFGQVAKCWKRSTKEI-VAIKILKNHPSYARQGQIEVSILSRLS- 242
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
++ D +V E L NL + LK+ K S + +K +R QQ+
Sbjct: 243 SENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPILQQVAT 301
Query: 747 XXXXXXXTGIVHADIKPDNILVNE---NKLNLKLCDFGAASQVTDNEITPYLVSRFYRAP 803
G++HAD+KP+NI++ + +K+ DFG+AS V+ + YL SR+YRAP
Sbjct: 302 ALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAP 361
Query: 804 EIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
EIILG+P+ IDMWS C I EL G ++ G S + ++Y
Sbjct: 362 EIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRY 403
>AB089957-1|BAC57075.1| 1210|Homo sapiens homeodomain-interacting
protein kinase-1 protein.
Length = 1210
Score = 129 bits (312), Expect = 4e-29
Identities = 74/222 (33%), Positives = 117/222 (52%), Gaps = 6/222 (2%)
Query: 627 TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLND 686
++ N Y V + G+G F V + ++ VA+KI++N+ + G E+ IL RL+
Sbjct: 185 SMTNSYEVLEFLGRGTFGQVAKCWKRSTKEI-VAIKILKNHPSYARQGQIEVSILSRLS- 242
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
++ D +V E L NL + LK+ K S + +K +R QQ+
Sbjct: 243 SENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPILQQVAT 301
Query: 747 XXXXXXXTGIVHADIKPDNILVNE---NKLNLKLCDFGAASQVTDNEITPYLVSRFYRAP 803
G++HAD+KP+NI++ + +K+ DFG+AS V+ + YL SR+YRAP
Sbjct: 302 ALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAP 361
Query: 804 EIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
EIILG+P+ IDMWS C I EL G ++ G S + ++Y
Sbjct: 362 EIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRY 403
>AC005393-2|AAC28914.1| 556|Homo sapiens BC331004_1 protein.
Length = 556
Score = 122 bits (295), Expect = 5e-27
Identities = 84/274 (30%), Positives = 128/274 (46%), Gaps = 25/274 (9%)
Query: 597 DSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSN 656
DS K E L +DD Y VR GE RY + G+G F VV+A D ++
Sbjct: 93 DSSNK--KEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDH-QTQ 149
Query: 657 TDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLS 716
VA+KII+N + EL +L+ +N D E +V E LS
Sbjct: 150 ELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLS 209
Query: 717 MNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXX--TGIVHADIKPDNILV-NENKL 773
NL ++L+ G+ + R QQ+ I+H D+KP+NIL+ N +
Sbjct: 210 YNLYDLLRN-THFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS 268
Query: 774 NLKLCDFGAASQVTDN------------------EITPYLVSRFYRAPEIILGVPYDHGI 815
+K+ DFG++ Q+ +I Y+ SRFYR+PE++LG PYD I
Sbjct: 269 AIKIVDFGSSCQLGQRLRMEVEGFNFAALYELPLKIYQYIQSRFYRSPEVLLGTPYDLAI 328
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
DMWS C + E+ TG+ +FSG + + + +++
Sbjct: 329 DMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEV 362
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 119 bits (287), Expect = 4e-26
Identities = 72/226 (31%), Positives = 124/226 (54%), Gaps = 17/226 (7%)
Query: 624 IGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMHKTGLRELEI 680
IG + N++ + G G+G + V++ R + ++ VA+K ++ NE + +T LREL++
Sbjct: 6 IGNVM-NKFEILGVVGEGAYGVVLKCRHK-ETHEIVAIKKFKDSEENEEVKETTLRELKM 63
Query: 681 LKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSY 740
L+ L + + +V E + N+ E+L++ +G+ + V+SY
Sbjct: 64 LRTLKQENIVELKEAFRRRGKLY------LVFEYVEKNMLELLEEMP--NGVPPEKVKSY 115
Query: 741 TQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE---ITPYLVS 797
Q+ IVH DIKP+N+L++ N + LKLCDFG A +++ T Y+ +
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISHNDV-LKLCDFGFARNLSEGNNANYTEYVAT 174
Query: 798 RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
R+YR+PE++LG PY +DMWS C + ELS G+ +F G+S + L
Sbjct: 175 RWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQL 220
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/31 (48%), Positives = 18/31 (58%)
Query: 927 SQLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
S L DL++ +L LDPA R CL HP Q
Sbjct: 268 SVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ 298
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 119 bits (287), Expect = 4e-26
Identities = 72/226 (31%), Positives = 124/226 (54%), Gaps = 17/226 (7%)
Query: 624 IGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMHKTGLRELEI 680
IG + N++ + G G+G + V++ R + ++ VA+K ++ NE + +T LREL++
Sbjct: 6 IGNVM-NKFEILGVVGEGAYGVVLKCRHK-ETHEIVAIKKFKDSEENEEVKETTLRELKM 63
Query: 681 LKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSY 740
L+ L + + +V E + N+ E+L++ +G+ + V+SY
Sbjct: 64 LRTLKQENIVELKEAFRRRGKLY------LVFEYVEKNMLELLEEMP--NGVPPEKVKSY 115
Query: 741 TQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE---ITPYLVS 797
Q+ IVH DIKP+N+L++ N + LKLCDFG A +++ T Y+ +
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISHNDV-LKLCDFGFARNLSEGNNANYTEYVAT 174
Query: 798 RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
R+YR+PE++LG PY +DMWS C + ELS G+ +F G+S + L
Sbjct: 175 RWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQL 220
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/31 (48%), Positives = 18/31 (58%)
Query: 927 SQLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
S L DL++ +L LDPA R CL HP Q
Sbjct: 268 SVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ 298
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 119 bits (287), Expect = 4e-26
Identities = 72/226 (31%), Positives = 124/226 (54%), Gaps = 17/226 (7%)
Query: 624 IGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMHKTGLRELEI 680
IG + N++ + G G+G + V++ R + ++ VA+K ++ NE + +T LREL++
Sbjct: 6 IGNVM-NKFEILGVVGEGAYGVVLKCRHK-ETHEIVAIKKFKDSEENEEVKETTLRELKM 63
Query: 681 LKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSY 740
L+ L + + +V E + N+ E+L++ +G+ + V+SY
Sbjct: 64 LRTLKQENIVELKEAFRRRGKLY------LVFEYVEKNMLELLEEMP--NGVPPEKVKSY 115
Query: 741 TQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE---ITPYLVS 797
Q+ IVH DIKP+N+L++ N + LKLCDFG A +++ T Y+ +
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISHNDV-LKLCDFGFARNLSEGNNANYTEYVAT 174
Query: 798 RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
R+YR+PE++LG PY +DMWS C + ELS G+ +F G+S + L
Sbjct: 175 RWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQL 220
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/31 (48%), Positives = 18/31 (58%)
Query: 927 SQLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
S L DL++ +L LDPA R CL HP Q
Sbjct: 268 SVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ 298
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 119 bits (287), Expect = 4e-26
Identities = 72/226 (31%), Positives = 124/226 (54%), Gaps = 17/226 (7%)
Query: 624 IGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMHKTGLRELEI 680
IG + N++ + G G+G + V++ R + ++ VA+K ++ NE + +T LREL++
Sbjct: 6 IGNVM-NKFEILGVVGEGAYGVVLKCRHK-ETHEIVAIKKFKDSEENEEVKETTLRELKM 63
Query: 681 LKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSY 740
L+ L + + +V E + N+ E+L++ +G+ + V+SY
Sbjct: 64 LRTLKQENIVELKEAFRRRGKLY------LVFEYVEKNMLELLEEMP--NGVPPEKVKSY 115
Query: 741 TQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE---ITPYLVS 797
Q+ IVH DIKP+N+L++ N + LKLCDFG A +++ T Y+ +
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISHNDV-LKLCDFGFARNLSEGNNANYTEYVAT 174
Query: 798 RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
R+YR+PE++LG PY +DMWS C + ELS G+ +F G+S + L
Sbjct: 175 RWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQL 220
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/31 (48%), Positives = 18/31 (58%)
Query: 927 SQLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
S L DL++ +L LDPA R CL HP Q
Sbjct: 268 SVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ 298
>BC034501-1|AAH34501.1| 616|Homo sapiens homeodomain interacting
protein kinase 4 protein.
Length = 616
Score = 118 bits (285), Expect = 8e-26
Identities = 94/342 (27%), Positives = 161/342 (47%), Gaps = 22/342 (6%)
Query: 632 YNVYGYTGQGVFSNVVRARDQARSNTD-VAVKIIRNNEIMHKTGLRELEILKRLNDADPE 690
Y++ G+G F V A+ RS + VA+KI++N+ ++ EL++L + DPE
Sbjct: 11 YDIIEVLGKGTFGEV--AKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLHCMRGLDPE 68
Query: 691 DXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXX 750
+ +V E L NL E +K + + + +R+ T Q+
Sbjct: 69 EAHVIRFLEFFHDALKFY-LVFELLEQNLFE-FQKENNFAPLPARHIRTVTLQVLTALAR 126
Query: 751 XXXTGIVHADIKPDNI-LVNENK--LNLKLCDFGAASQVTDNEIT--PYLVSRFYRAPEI 805
I+HAD+KP+NI LV++ + +K+ DFG+AS ++ PY+ SRFYRAPEI
Sbjct: 127 LKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEI 186
Query: 806 ILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDLXX----XXXXXXXXXX 861
+LG+P+ +D+WS C + EL G ++ G + + ++Y +
Sbjct: 187 LLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAACKAH 246
Query: 862 HF--KEQHFD-ANCNFLYHELDKITERNFTLCQQEKVVI--ISSIKPTR--DLQTELAPP 914
HF + H D AN L D + E ++ K ++ + I+ + + L P
Sbjct: 247 HFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVASRLTFP 306
Query: 915 HHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
R L E + + +L++RML + +R S + L HPF+
Sbjct: 307 -DREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFV 347
>AK057380-1|BAB71458.1| 541|Homo sapiens protein ( Homo sapiens
cDNA FLJ32818 fis, clone TESTI2002912, weakly similar to
DUAL-SPECIFICITY TYROSINE-(Y)-PHOSPHORYLATION REGULATED
KINASE ).
Length = 541
Score = 109 bits (263), Expect = 3e-23
Identities = 68/223 (30%), Positives = 116/223 (52%), Gaps = 10/223 (4%)
Query: 632 YNVYGYTGQGVFSNVVRARDQARSNTD-VAVKIIRNNEIMHKTGLRELEILKRLNDADPE 690
Y++ G+G F V A+ RS + VA+KI++N+ ++ EL++L + DPE
Sbjct: 11 YDIIEVLGKGTFGEV--AKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLHCMRGLDPE 68
Query: 691 DXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXX 750
+ +V E L NL E +K + + + +R+ T Q+
Sbjct: 69 EAHVIRFLEFFHDALKFY-LVFELLEQNLFE-FQKENNFAPLPARHIRTVTLQVLTALAR 126
Query: 751 XXXTGIVHADIKPDNI-LVNENK--LNLKLCDFGAASQVTDNEIT--PYLVSRFYRAPEI 805
I+HAD+KP+NI LV++ + +K+ DFG+AS ++ PY+ SRFYRAPEI
Sbjct: 127 LKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEI 186
Query: 806 ILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMD 848
+LG+P+ +D+WS C + EL G ++ G + + ++Y +
Sbjct: 187 LLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICE 229
>L29218-1|AAA61482.1| 499|Homo sapiens clk2 protein.
Length = 499
Score = 108 bits (259), Expect = 1e-22
Identities = 102/361 (28%), Positives = 154/361 (42%), Gaps = 46/361 (12%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DDAEG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 145 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 204
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +L+++N+ DP++ + E L ++ + LK
Sbjct: 205 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYP 263
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I VR Q+ + H D+KP+NIL VN E K + +
Sbjct: 264 IHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAV 323
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 324 RVVDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 381
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N E L M+ K+++F LD + N + +
Sbjct: 382 QTHDNREHLA-MMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 429
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A HH QL DL+E ML +PAKR ++ L HP
Sbjct: 430 -YVRENCKPLRRYLTSEAEEHH-----------QLFDLIESMLEYEPAKRLTLGEALQHP 477
Query: 955 F 955
F
Sbjct: 478 F 478
>BC053603-1|AAH53603.1| 499|Homo sapiens CDC-like kinase 2 protein.
Length = 499
Score = 108 bits (259), Expect = 1e-22
Identities = 102/361 (28%), Positives = 154/361 (42%), Gaps = 46/361 (12%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DDAEG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 145 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 204
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +L+++N+ DP++ + E L ++ + LK
Sbjct: 205 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYP 263
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I VR Q+ + H D+KP+NIL VN E K + +
Sbjct: 264 IHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAV 323
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 324 RVVDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 381
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N E L M+ K+++F LD + N + +
Sbjct: 382 QTHDNREHLA-MMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 429
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A HH QL DL+E ML +PAKR ++ L HP
Sbjct: 430 -YVRENCKPLRRYLTSEAEEHH-----------QLFDLIESMLEYEPAKRLTLGEALQHP 477
Query: 955 F 955
F
Sbjct: 478 F 478
>BC014067-1|AAH14067.1| 498|Homo sapiens CDC-like kinase 2 protein.
Length = 498
Score = 108 bits (259), Expect = 1e-22
Identities = 102/361 (28%), Positives = 154/361 (42%), Gaps = 46/361 (12%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DDAEG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 144 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 203
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +L+++N+ DP++ + E L ++ + LK
Sbjct: 204 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYP 262
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I VR Q+ + H D+KP+NIL VN E K + +
Sbjct: 263 IHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAV 322
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 323 RVVDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 380
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N E L M+ K+++F LD + N + +
Sbjct: 381 QTHDNREHLA-MMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 428
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A HH QL DL+E ML +PAKR ++ L HP
Sbjct: 429 -YVRENCKPLRRYLTSEAEEHH-----------QLFDLIESMLEYEPAKRLTLGEALQHP 476
Query: 955 F 955
F
Sbjct: 477 F 477
>AL713999-30|CAI95098.1| 498|Homo sapiens CDC-like kinase 2
protein.
Length = 498
Score = 108 bits (259), Expect = 1e-22
Identities = 102/361 (28%), Positives = 154/361 (42%), Gaps = 46/361 (12%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DDAEG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 144 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 203
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +L+++N+ DP++ + E L ++ + LK
Sbjct: 204 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYP 262
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I VR Q+ + H D+KP+NIL VN E K + +
Sbjct: 263 IHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAV 322
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 323 RVVDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 380
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N E L M+ K+++F LD + N + +
Sbjct: 381 QTHDNREHLA-MMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 428
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A HH QL DL+E ML +PAKR ++ L HP
Sbjct: 429 -YVRENCKPLRRYLTSEAEEHH-----------QLFDLIESMLEYEPAKRLTLGEALQHP 476
Query: 955 F 955
F
Sbjct: 477 F 477
>AL713999-29|CAI95097.1| 497|Homo sapiens CDC-like kinase 2
protein.
Length = 497
Score = 108 bits (259), Expect = 1e-22
Identities = 102/361 (28%), Positives = 154/361 (42%), Gaps = 46/361 (12%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DDAEG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 143 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 202
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +L+++N+ DP++ + E L ++ + LK
Sbjct: 203 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYP 261
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I VR Q+ + H D+KP+NIL VN E K + +
Sbjct: 262 IHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAV 321
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 322 RVVDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 379
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N E L M+ K+++F LD + N + +
Sbjct: 380 QTHDNREHLA-MMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 427
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A HH QL DL+E ML +PAKR ++ L HP
Sbjct: 428 -YVRENCKPLRRYLTSEAEEHH-----------QLFDLIESMLEYEPAKRLTLGEALQHP 475
Query: 955 F 955
F
Sbjct: 476 F 476
>AL713999-28|CAI95099.1| 499|Homo sapiens CDC-like kinase 2
protein.
Length = 499
Score = 108 bits (259), Expect = 1e-22
Identities = 102/361 (28%), Positives = 154/361 (42%), Gaps = 46/361 (12%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DDAEG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 145 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 204
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +L+++N+ DP++ + E L ++ + LK
Sbjct: 205 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYP 263
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I VR Q+ + H D+KP+NIL VN E K + +
Sbjct: 264 IHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAV 323
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 324 RVVDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 381
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N E L M+ K+++F LD + N + +
Sbjct: 382 QTHDNREHLA-MMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 429
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A HH QL DL+E ML +PAKR ++ L HP
Sbjct: 430 -YVRENCKPLRRYLTSEAEEHH-----------QLFDLIESMLEYEPAKRLTLGEALQHP 477
Query: 955 F 955
F
Sbjct: 478 F 478
>AF023268-1|AAC51817.1| 499|Homo sapiens clk2 kinase protein.
Length = 499
Score = 108 bits (259), Expect = 1e-22
Identities = 102/361 (28%), Positives = 154/361 (42%), Gaps = 46/361 (12%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DDAEG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 145 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA 204
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +L+++N+ DP++ + E L ++ + LK
Sbjct: 205 ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKD-NNYLPYP 263
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I VR Q+ + H D+KP+NIL VN E K + +
Sbjct: 264 IHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAV 323
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 324 RVVDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 381
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N E L M+ K+++F LD + N + +
Sbjct: 382 QTHDNREHLA-MMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 429
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A HH QL DL+E ML +PAKR ++ L HP
Sbjct: 430 -YVRENCKPLRRYLTSEAEEHH-----------QLFDLIESMLEYEPAKRLTLGEALQHP 477
Query: 955 F 955
F
Sbjct: 478 F 478
>BT006993-1|AAP35639.1| 490|Homo sapiens CDC-like kinase 3 protein.
Length = 490
Score = 105 bits (251), Expect = 1e-21
Identities = 90/349 (25%), Positives = 153/349 (43%), Gaps = 28/349 (8%)
Query: 520 SQRSVSPT-SKNKSHD---HKEKNKEERKH--IRTETRSETLIKKIENESKSTIKLQKSN 573
S+R P S+++SHD ++ + +E R R E RS + + S+S + +
Sbjct: 38 SRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRE 97
Query: 574 KDS-EWDMFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRY 632
+ A + + ++ S+++ +++ S + DD EG+ RIG+ L RY
Sbjct: 98 RGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVE-DDKEGHLVCRIGDWLQERY 156
Query: 633 NVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDX 692
+ G G+G F VV D AR + VA+KIIRN + E+ +LK++ + D E+
Sbjct: 157 EIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENK 216
Query: 693 XXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXX 752
+ E L N E LK+ + VR Q+
Sbjct: 217 FLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKE-NNFQPYPLPHVRHMAYQLCHALRFLH 275
Query: 753 XTGIVHADIKPDNILV---------NENK---------LNLKLCDFGAASQVTDNEITPY 794
+ H D+KP+NIL NE+K ++++ DFG+A+ ++ T
Sbjct: 276 ENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTT-I 334
Query: 795 LVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+ +R YR PE+IL + + D+WS C ++E G +F N E L
Sbjct: 335 VATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHL 383
>BC019881-1|AAH19881.1| 490|Homo sapiens CLK3 protein protein.
Length = 490
Score = 105 bits (251), Expect = 1e-21
Identities = 90/349 (25%), Positives = 153/349 (43%), Gaps = 28/349 (8%)
Query: 520 SQRSVSPT-SKNKSHD---HKEKNKEERKH--IRTETRSETLIKKIENESKSTIKLQKSN 573
S+R P S+++SHD ++ + +E R R E RS + + S+S + +
Sbjct: 38 SRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRE 97
Query: 574 KDS-EWDMFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRY 632
+ A + + ++ S+++ +++ S + DD EG+ RIG+ L RY
Sbjct: 98 RGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVE-DDKEGHLVCRIGDWLQERY 156
Query: 633 NVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDX 692
+ G G+G F VV D AR + VA+KIIRN + E+ +LK++ + D E+
Sbjct: 157 EIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENK 216
Query: 693 XXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXX 752
+ E L N E LK+ + VR Q+
Sbjct: 217 FLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKE-NNFQPYPLPHVRHMAYQLCHALRFLH 275
Query: 753 XTGIVHADIKPDNILV---------NENK---------LNLKLCDFGAASQVTDNEITPY 794
+ H D+KP+NIL NE+K ++++ DFG+A+ ++ T
Sbjct: 276 ENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTT-I 334
Query: 795 LVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+ +R YR PE+IL + + D+WS C ++E G +F N E L
Sbjct: 335 VATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHL 383
>BC002555-1|AAH02555.1| 490|Homo sapiens CDC-like kinase 3 protein.
Length = 490
Score = 105 bits (251), Expect = 1e-21
Identities = 90/349 (25%), Positives = 153/349 (43%), Gaps = 28/349 (8%)
Query: 520 SQRSVSPT-SKNKSHD---HKEKNKEERKH--IRTETRSETLIKKIENESKSTIKLQKSN 573
S+R P S+++SHD ++ + +E R R E RS + + S+S + +
Sbjct: 38 SRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRE 97
Query: 574 KDS-EWDMFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEGYYRVRIGETLDNRY 632
+ A + + ++ S+++ +++ S + DD EG+ RIG+ L RY
Sbjct: 98 RGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVE-DDKEGHLVCRIGDWLQERY 156
Query: 633 NVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDX 692
+ G G+G F VV D AR + VA+KIIRN + E+ +LK++ + D E+
Sbjct: 157 EIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENK 216
Query: 693 XXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXX 752
+ E L N E LK+ + VR Q+
Sbjct: 217 FLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKE-NNFQPYPLPHVRHMAYQLCHALRFLH 275
Query: 753 XTGIVHADIKPDNILV---------NENK---------LNLKLCDFGAASQVTDNEITPY 794
+ H D+KP+NIL NE+K ++++ DFG+A+ ++ T
Sbjct: 276 ENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTT-I 334
Query: 795 LVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+ +R YR PE+IL + + D+WS C ++E G +F N E L
Sbjct: 335 VATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHL 383
>L29217-1|AAA61484.1| 490|Homo sapiens clk3 protein.
Length = 490
Score = 104 bits (250), Expect = 1e-21
Identities = 72/248 (29%), Positives = 110/248 (44%), Gaps = 20/248 (8%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DD EG+ RIG+ L RY + G G+G F VV D AR + VA+KIIRN +
Sbjct: 138 DDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREA 197
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +LK++ + D E+ + E L N E LK+
Sbjct: 198 ARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKE-NNFQPYP 256
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILV---------NENK---------LNL 775
+ VR Q+ + H D+KP+NIL NE+K ++
Sbjct: 257 LPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSI 316
Query: 776 KLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFS 835
++ DFG+A+ ++ T + +R YR PE+IL + + D+WS C ++E G +F
Sbjct: 317 RVADFGSATFDHEHHTT-IVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQ 375
Query: 836 GKSNNEML 843
N E L
Sbjct: 376 THENREHL 383
>AB209535-1|BAD92772.1| 565|Homo sapiens Dual specificity protein
kinase CLK3 variant protein.
Length = 565
Score = 104 bits (250), Expect = 1e-21
Identities = 72/248 (29%), Positives = 110/248 (44%), Gaps = 20/248 (8%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DD EG+ RIG+ L RY + G G+G F VV D AR + VA+KIIRN +
Sbjct: 213 DDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREA 272
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+ +LK++ + D E+ + E L N E LK+
Sbjct: 273 ARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKE-NNFQPYP 331
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILV---------NENK---------LNL 775
+ VR Q+ + H D+KP+NIL NE+K ++
Sbjct: 332 LPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSI 391
Query: 776 KLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFS 835
++ DFG+A+ ++ T + +R YR PE+IL + + D+WS C ++E G +F
Sbjct: 392 RVADFGSATFDHEHHTT-IVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQ 450
Query: 836 GKSNNEML 843
N E L
Sbjct: 451 THENREHL 458
>X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal
regulated kinase protein.
Length = 367
Score = 103 bits (248), Expect = 2e-21
Identities = 71/237 (29%), Positives = 113/237 (47%), Gaps = 14/237 (5%)
Query: 618 GYYRVRIGETLDNRYNVYGY---TGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMH 671
G+YR + +T VY G G + V A D R+ VA+K + +E+
Sbjct: 10 GFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVD-GRTGAKVAIKKLYRPFQSELFA 68
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
K REL +LK + + +V+ + +L +++K +
Sbjct: 69 KLAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMK----HEK 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ ++ QM GI+H D+KP N+ VNE+ LK+ DFG A Q D+E+
Sbjct: 125 LGEDRIQFLVYQMMKGLRYIHAAGIIHRDLKPGNLAVNED-CELKILDFGLARQA-DSEM 182
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
T Y+V+R+YRAPE+IL + Y +D+WS C + E+ TGK +F G + + LK M
Sbjct: 183 TGYVVTRWYRAPEVILNWIAYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIM 239
>Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein
kinase-3 protein.
Length = 367
Score = 102 bits (245), Expect = 5e-21
Identities = 71/237 (29%), Positives = 113/237 (47%), Gaps = 14/237 (5%)
Query: 618 GYYRVRIGETLDNRYNVYGY---TGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMH 671
G+YR + +T VY G G + V A D R+ VA+K + +E+
Sbjct: 10 GFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVD-GRTGAKVAIKKLYRPFQSELFA 68
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
K REL +LK + + +V+ + +L +++K +
Sbjct: 69 KRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMK----HEK 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ ++ QM GI+H D+KP N+ VNE+ LK+ DFG A Q D+E+
Sbjct: 125 LGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNED-CELKILDFGLARQA-DSEM 182
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
T Y+V+R+YRAPE+IL + Y +D+WS C + E+ TGK +F G + + LK M
Sbjct: 183 TGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIM 239
>U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein.
Length = 367
Score = 102 bits (245), Expect = 5e-21
Identities = 71/237 (29%), Positives = 113/237 (47%), Gaps = 14/237 (5%)
Query: 618 GYYRVRIGETLDNRYNVYGY---TGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMH 671
G+YR + +T VY G G + V A D R+ VA+K + +E+
Sbjct: 10 GFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVD-GRTGAKVAIKKLYRPFQSELFA 68
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
K REL +LK + + +V+ + +L +++K +
Sbjct: 69 KRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMK----HEK 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ ++ QM GI+H D+KP N+ VNE+ LK+ DFG A Q D+E+
Sbjct: 125 LGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNED-CELKILDFGLARQA-DSEM 182
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
T Y+V+R+YRAPE+IL + Y +D+WS C + E+ TGK +F G + + LK M
Sbjct: 183 TGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIM 239
>BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 102 bits (245), Expect = 5e-21
Identities = 71/237 (29%), Positives = 113/237 (47%), Gaps = 14/237 (5%)
Query: 618 GYYRVRIGETLDNRYNVYGY---TGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMH 671
G+YR + +T VY G G + V A D R+ VA+K + +E+
Sbjct: 10 GFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVD-GRTGAKVAIKKLYRPFQSELFA 68
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
K REL +LK + + +V+ + +L +++K +
Sbjct: 69 KRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMK----HEK 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ ++ QM GI+H D+KP N+ VNE+ LK+ DFG A Q D+E+
Sbjct: 125 LGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNED-CELKILDFGLARQA-DSEM 182
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
T Y+V+R+YRAPE+IL + Y +D+WS C + E+ TGK +F G + + LK M
Sbjct: 183 TGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIM 239
>AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 102 bits (245), Expect = 5e-21
Identities = 71/237 (29%), Positives = 113/237 (47%), Gaps = 14/237 (5%)
Query: 618 GYYRVRIGETLDNRYNVYGY---TGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMH 671
G+YR + +T VY G G + V A D R+ VA+K + +E+
Sbjct: 10 GFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVD-GRTGAKVAIKKLYRPFQSELFA 68
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
K REL +LK + + +V+ + +L +++K +
Sbjct: 69 KRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMK----HEK 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ ++ QM GI+H D+KP N+ VNE+ LK+ DFG A Q D+E+
Sbjct: 125 LGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNED-CELKILDFGLARQA-DSEM 182
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
T Y+V+R+YRAPE+IL + Y +D+WS C + E+ TGK +F G + + LK M
Sbjct: 183 TGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIM 239
>U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein.
Length = 372
Score = 101 bits (243), Expect = 9e-21
Identities = 72/243 (29%), Positives = 115/243 (47%), Gaps = 14/243 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLK-KYGKNS 730
+ REL +LK L + +V + +L ++K + G +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQAGAHQ 125
Query: 731 GIHI---KAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT 787
G + + V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q
Sbjct: 126 GARLALDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA- 183
Query: 788 DNEITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYF 846
D E+T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK
Sbjct: 184 DEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 243
Query: 847 MDL 849
M++
Sbjct: 244 MEV 246
>Z95152-3|CAB08438.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein
kinase-4 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
>CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protein
kinase 4 protein.
Length = 365
Score = 101 bits (242), Expect = 1e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>AJ001870-1|CAA05059.1| 147|Homo sapiens MNB protein kinase
protein.
Length = 147
Score = 101 bits (241), Expect = 2e-20
Identities = 51/143 (35%), Positives = 83/143 (58%), Gaps = 5/143 (3%)
Query: 710 MVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXT--GIVHADIKPDNIL 767
+V E LS NL ++L+ G+ + R + QQM I+H D+KP+NIL
Sbjct: 3 LVFEMLSYNLYDLLRNTNFR-GVSLNLTRKFVQQMCTALLFLATPELSIIHCDLKPENIL 61
Query: 768 V-NENKLNLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYE 826
+ N + +K+ DFG++ Q+ I Y+ SRFYR+PE++LG+PYD IDMWS C + E
Sbjct: 62 LCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVE 120
Query: 827 LSTGKIMFSGKSNNEMLKYFMDL 849
+ T + +FSG + + + +++
Sbjct: 121 MHTREPLFSGANEVDQMNKIVEV 143
>AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated protein
kinase p38delta protein.
Length = 365
Score = 101 bits (241), Expect = 2e-20
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFRGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase 3
protein.
Length = 483
Score = 99.5 bits (237), Expect = 5e-20
Identities = 67/208 (32%), Positives = 100/208 (48%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +AR A + VA+K + ++ REL+I+++L+ +
Sbjct: 126 GNGSFGVVYQAR-LAETRELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 181
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS-GIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VLE + + V + + K I I V+ Y Q+ G+
Sbjct: 182 SGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVC 241
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+LV+ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 242 HRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 301
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 302 DVWSAGCVLAELLLGQPIFPGDSGVDQL 329
>D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase
3alpha protein.
Length = 483
Score = 99.5 bits (237), Expect = 5e-20
Identities = 67/208 (32%), Positives = 100/208 (48%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +AR A + VA+K + ++ REL+I+++L+ +
Sbjct: 126 GNGSFGVVYQAR-LAETRELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 181
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS-GIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VLE + + V + + K I I V+ Y Q+ G+
Sbjct: 182 SGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVC 241
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+LV+ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 242 HRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 301
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 302 DVWSAGCVLAELLLGQPIFPGDSGVDQL 329
>BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinase 3
alpha protein.
Length = 483
Score = 99.5 bits (237), Expect = 5e-20
Identities = 67/208 (32%), Positives = 100/208 (48%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +AR A + VA+K + ++ REL+I+++L+ +
Sbjct: 126 GNGSFGVVYQAR-LAETRELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 181
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS-GIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VLE + + V + + K I I V+ Y Q+ G+
Sbjct: 182 SGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVC 241
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+LV+ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 242 HRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 301
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 302 DVWSAGCVLAELLLGQPIFPGDSGVDQL 329
>BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinase 3
alpha protein.
Length = 483
Score = 99.5 bits (237), Expect = 5e-20
Identities = 67/208 (32%), Positives = 100/208 (48%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +AR A + VA+K + ++ REL+I+++L+ +
Sbjct: 126 GNGSFGVVYQAR-LAETRELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 181
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS-GIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VLE + + V + + K I I V+ Y Q+ G+
Sbjct: 182 SGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVC 241
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+LV+ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 242 HRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 301
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 302 DVWSAGCVLAELLLGQPIFPGDSGVDQL 329
>AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragment)
variant protein.
Length = 307
Score = 99.5 bits (237), Expect = 5e-20
Identities = 67/228 (29%), Positives = 111/228 (48%), Gaps = 15/228 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 4 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 62
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 63 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 117
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ Q+ G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 118 EFSEEKIQYLVYQVLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 175
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGK 837
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK
Sbjct: 176 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGK 223
>AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein.
Length = 483
Score = 99.5 bits (237), Expect = 5e-20
Identities = 67/208 (32%), Positives = 100/208 (48%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +AR A + VA+K + ++ REL+I+++L+ +
Sbjct: 126 GNGSFGVVYQAR-LAETRELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 181
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS-GIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VLE + + V + + K I I V+ Y Q+ G+
Sbjct: 182 SGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVC 241
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+LV+ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 242 HRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 301
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 302 DVWSAGCVLAELLLGQPIFPGDSGVDQL 329
>AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protein
kinase 4 protein.
Length = 365
Score = 99.1 bits (236), Expect = 7e-20
Identities = 68/234 (29%), Positives = 112/234 (47%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + + A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQELNKTAWELPKTYVSPTHVGSGAYGSWCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKILDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein
kinase-2b protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein
kinase p38-2 protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated
protein kinase protein.
Length = 365
Score = 98.7 bits (235), Expect = 9e-20
Identities = 69/234 (29%), Positives = 112/234 (47%), Gaps = 15/234 (6%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKPSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-----GM 120
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
+ ++ QM G+VH D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 121 EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNED-CELKVLDFGLARHA-DAE 178
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFRGKDYLDQL 232
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 280 QAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase
protein.
Length = 364
Score = 98.7 bits (235), Expect = 9e-20
Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 618 GYYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH- 671
G+YR + +T+ R G G + +V A D AR VAVK + ++H
Sbjct: 7 GFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYD-ARLRQKVAVKKLSRPFQSLIHA 65
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
+ REL +LK L + +V + +L ++K +
Sbjct: 66 RRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD- 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ V+ Q+ GI+H D+KP N+ VNE+ L++ DFG A Q D E+
Sbjct: 125 ---EHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNED-CELRILDFGLARQA-DEEM 179
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
T Y+ +R+YRAPEI+L + Y+ +D+WS C + EL GK +F G + LK M++
Sbjct: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEV 238
>U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein.
Length = 297
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein.
Length = 360
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein.
Length = 360
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protein
kinase 2a protein.
Length = 360
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced
variant of p38alpha EXIP protein.
Length = 307
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + + LK + L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
>L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 96.7 bits (230), Expect = 3e-19
Identities = 70/238 (29%), Positives = 113/238 (47%), Gaps = 14/238 (5%)
Query: 619 YYRVRIGETL---DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN--NEIMH-K 672
+YR + +T+ RY G G + +V A D ++ VAVK + I+H K
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFD-TKTGLRVAVKKLSRPFQSIIHAK 66
Query: 673 TGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGI 732
REL +LK + + +V + +L ++K K +
Sbjct: 67 RTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ-KLTDD 125
Query: 733 HIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEIT 792
H++ + Q+ I+H D+KP N+ VNE+ LK+ DFG A TD+E+T
Sbjct: 126 HVQFL---IYQILRGLKYIHSADIIHRDLKPSNLAVNED-CELKILDFGLARH-TDDEMT 180
Query: 793 PYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y+ +R+YRAPEI+L + Y+ +D+WS C + EL TG+ +F G + L+ M L
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRL 238
>BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein.
Length = 231
Score = 95.5 bits (227), Expect = 8e-19
Identities = 60/221 (27%), Positives = 106/221 (47%), Gaps = 10/221 (4%)
Query: 632 YNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTG-LRELEILKRLNDADPE 690
Y G G+G FS V++ + N ++ + E + + LRE++ L+RLN P
Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLN---PH 60
Query: 691 DXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXX 750
++ E + MN+ E+++ G+ + K + Y Q+
Sbjct: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIR--GRRYPLSEKKIMHYMYQLCKSLDH 118
Query: 751 XXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILGV 809
GI H D+KP+NIL+ ++ LKL DFG+ V + T Y+ +R+YRAPE +L
Sbjct: 119 IHRNGIFHRDVKPENILIKQDV--LKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTD 176
Query: 810 P-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y + +D+WS C YE+++ + +F G + + + D+
Sbjct: 177 GFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDV 217
>AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase
protein.
Length = 419
Score = 95.5 bits (227), Expect = 8e-19
Identities = 60/221 (27%), Positives = 106/221 (47%), Gaps = 10/221 (4%)
Query: 632 YNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTG-LRELEILKRLNDADPE 690
Y G G+G FS V++ + N ++ + E + + LRE++ L+RLN P
Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLN---PH 60
Query: 691 DXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXX 750
++ E + MN+ E+++ G+ + K + Y Q+
Sbjct: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIR--GRRYPLSEKKIMHYMYQLCKSLDH 118
Query: 751 XXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILGV 809
GI H D+KP+NIL+ ++ LKL DFG+ V + T Y+ +R+YRAPE +L
Sbjct: 119 IHRNGIFHRDVKPENILIKQDV--LKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTD 176
Query: 810 P-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
Y + +D+WS C YE+++ + +F G + + + D+
Sbjct: 177 GFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDV 217
>U35003-1|AAC50609.1| 424|Homo sapiens JNK2 beta2 protein kinase
protein.
Length = 424
Score = 95.1 bits (226), Expect = 1e-18
Identities = 67/235 (28%), Positives = 110/235 (46%), Gaps = 13/235 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D + K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGISVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + E+ K++F G+
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGR 228
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>U35002-1|AAC50608.1| 382|Homo sapiens JNK2 beta1 protein kinase
protein.
Length = 382
Score = 95.1 bits (226), Expect = 1e-18
Identities = 67/235 (28%), Positives = 110/235 (46%), Gaps = 13/235 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D + K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGISVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + E+ K++F G+
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGR 228
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>U34820-1|AAC50605.1| 422|Homo sapiens JNK3 alpha1 protein kinase
protein.
Length = 422
Score = 95.1 bits (226), Expect = 1e-18
Identities = 66/225 (29%), Positives = 102/225 (45%), Gaps = 12/225 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V +G+ T+ RY G G V A D K+ R N+ K
Sbjct: 48 FYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKR 107
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 108 AYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-----LD 162
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 163 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 221
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ KI+F G+
Sbjct: 222 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGR 266
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/32 (59%), Positives = 25/32 (78%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DPAKR SV+ L HP+I
Sbjct: 328 KASQARDLLSKMLVIDPAKRISVDDALQHPYI 359
>U34819-1|AAC50604.1| 464|Homo sapiens JNK3 alpha2 protein kinase
protein.
Length = 464
Score = 95.1 bits (226), Expect = 1e-18
Identities = 66/225 (29%), Positives = 102/225 (45%), Gaps = 12/225 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V +G+ T+ RY G G V A D K+ R N+ K
Sbjct: 48 FYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKR 107
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 108 AYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-----LD 162
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 163 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 221
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ KI+F G+
Sbjct: 222 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGR 266
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/32 (59%), Positives = 25/32 (78%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DPAKR SV+ L HP+I
Sbjct: 328 KASQARDLLSKMLVIDPAKRISVDDALQHPYI 359
>U07620-1|AAC50101.1| 422|Homo sapiens MAP kinase protein.
Length = 422
Score = 95.1 bits (226), Expect = 1e-18
Identities = 66/225 (29%), Positives = 102/225 (45%), Gaps = 12/225 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V +G+ T+ RY G G V A D K+ R N+ K
Sbjct: 48 FYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKR 107
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 108 AYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-----LD 162
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 163 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 221
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ KI+F G+
Sbjct: 222 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGR 266
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/32 (59%), Positives = 25/32 (78%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DPAKR SV+ L HP+I
Sbjct: 328 KASQARDLLSKMLVIDPAKRISVDDALQHPYI 359
>L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein.
Length = 420
Score = 95.1 bits (226), Expect = 1e-18
Identities = 63/208 (30%), Positives = 99/208 (47%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +A+ S VA+K + ++ REL+I+++L+ +
Sbjct: 63 GNGSFGVVYQAK-LCDSGELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 118
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGK-NSGIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VL+ + + V + Y + + + V+ Y Q+ GI
Sbjct: 119 SGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGIC 178
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+L++ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 179 HRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 238
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 239 DVWSAGCVLAELLLGQPIFPGDSGVDQL 266
>CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein.
Length = 420
Score = 95.1 bits (226), Expect = 1e-18
Identities = 63/208 (30%), Positives = 99/208 (47%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +A+ S VA+K + ++ REL+I+++L+ +
Sbjct: 63 GNGSFGVVYQAK-LCDSGELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 118
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGK-NSGIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VL+ + + V + Y + + + V+ Y Q+ GI
Sbjct: 119 SGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGIC 178
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+L++ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 179 HRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 238
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 239 DVWSAGCVLAELLLGQPIFPGDSGVDQL 266
>BC035057-1|AAH35057.1| 464|Homo sapiens MAPK10 protein protein.
Length = 464
Score = 95.1 bits (226), Expect = 1e-18
Identities = 66/225 (29%), Positives = 102/225 (45%), Gaps = 12/225 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V +G+ T+ RY G G V A D K+ R N+ K
Sbjct: 48 FYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKR 107
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 108 AYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-----LD 162
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 163 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 221
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ KI+F G+
Sbjct: 222 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGR 266
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/32 (59%), Positives = 25/32 (78%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DPAKR SV+ L HP+I
Sbjct: 328 KASQARDLLSKMLVIDPAKRISVDDALQHPYI 359
>BC022025-1|AAH22025.1| 493|Homo sapiens CLK2P protein protein.
Length = 493
Score = 95.1 bits (226), Expect = 1e-18
Identities = 98/361 (27%), Positives = 152/361 (42%), Gaps = 47/361 (13%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DD EG+ +G+ L RY + G+G F VV+ D R VA+KII+N E +
Sbjct: 140 DDTEGHLIYHVGDWLQERYEIVSTLGKGTFGRVVQCVDHRRRGARVALKIIKNVEKYKEA 199
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+++L+++N+ DP + LE L ++ + LK +
Sbjct: 200 ARLEIKVLEKINEKDP-GKNLCVQMFDWFDYHGHMCISLELLGLSTFDFLKD-NNHLPYP 257
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNIL-VN---------ENKLN--------L 775
I V Q+ + H D+KP+NIL VN E K + +
Sbjct: 258 IHQVHHMASQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRHERSVKSTAV 317
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
++ DFG+A+ D+E +VS R YRAPE+IL + + D+WS C I+E G +F
Sbjct: 318 RVGDFGSAT--FDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLF 375
Query: 835 SGKSNNEMLKYFMDLXXXXXXXXXXXXHFKEQHFDANCNFLYHELDKITERNFTLCQQEK 894
N + L M+ K+++F LD + N + +
Sbjct: 376 QTHDNRQHLA-TMERILGPIPSRMIRKTRKQKYFYRG------RLD--WDENTSAGR--- 423
Query: 895 VVIISSIKPTRDLQTELAPPHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHP 954
+ + KP R T A H QL DL+E ML +PA+R ++ L HP
Sbjct: 424 -YVRENCKPLRQYLTSEAEEDH-----------QLFDLIESMLEYEPAQRLTLGEALQHP 471
Query: 955 F 955
F
Sbjct: 472 F 472
>BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein.
Length = 420
Score = 95.1 bits (226), Expect = 1e-18
Identities = 63/208 (30%), Positives = 99/208 (47%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +A+ S VA+K + ++ REL+I+++L+ +
Sbjct: 63 GNGSFGVVYQAK-LCDSGELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 118
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGK-NSGIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VL+ + + V + Y + + + V+ Y Q+ GI
Sbjct: 119 SGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGIC 178
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+L++ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 179 HRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 238
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 239 DVWSAGCVLAELLLGQPIFPGDSGVDQL 266
>BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinase 3
beta protein.
Length = 433
Score = 95.1 bits (226), Expect = 1e-18
Identities = 63/208 (30%), Positives = 99/208 (47%), Gaps = 7/208 (3%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGLRELEILKRLNDADPEDXXXXXXX 698
G G F V +A+ S VA+K + ++ REL+I+++L+ +
Sbjct: 63 GNGSFGVVYQAK-LCDSGELVAIKKVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYS 118
Query: 699 XXXXXXXXXXXMVLEPLSMNLREVLKKYGK-NSGIHIKAVRSYTQQMXXXXXXXXXTGIV 757
+VL+ + + V + Y + + + V+ Y Q+ GI
Sbjct: 119 SGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGIC 178
Query: 758 HADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEIILG-VPYDHGI 815
H DIKP N+L++ + LKLCDFG+A Q+ E Y+ SR+YRAPE+I G Y I
Sbjct: 179 HRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSI 238
Query: 816 DMWSTACTIYELSTGKIMFSGKSNNEML 843
D+WS C + EL G+ +F G S + L
Sbjct: 239 DVWSAGCVLAELLLGQPIFPGDSGVDQL 266
>U34822-1|AAC50607.1| 427|Homo sapiens JNK1 alpha2 protein kinase
protein.
Length = 427
Score = 94.7 bits (225), Expect = 1e-18
Identities = 67/225 (29%), Positives = 102/225 (45%), Gaps = 12/225 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V IG+ T+ RY G G V A D K+ R N+ K
Sbjct: 10 FYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKR 69
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 70 AYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-----LD 124
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 125 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 183
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ KI+F G+
Sbjct: 184 PYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGR 228
Score = 40.7 bits (91), Expect = 0.024
Identities = 17/32 (53%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++D +KR SV+ L HP+I
Sbjct: 290 KASQARDLLSKMLVIDASKRISVDEALQHPYI 321
>U34821-1|AAC50606.1| 382|Homo sapiens JNK2 alpha1 protein kinase
protein.
Length = 382
Score = 94.7 bits (225), Expect = 1e-18
Identities = 68/234 (29%), Positives = 109/234 (46%), Gaps = 13/234 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D + K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGISVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + EL G ++F G
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQG 227
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>L31951-1|AAA56831.1| 424|Homo sapiens protein kinase protein.
Length = 424
Score = 94.7 bits (225), Expect = 1e-18
Identities = 68/234 (29%), Positives = 109/234 (46%), Gaps = 13/234 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D + K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGISVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + EL G ++F G
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQG 227
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>L26318-1|AAA36131.1| 384|Homo sapiens protein kinase protein.
Length = 384
Score = 94.7 bits (225), Expect = 1e-18
Identities = 67/225 (29%), Positives = 102/225 (45%), Gaps = 12/225 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V IG+ T+ RY G G V A D K+ R N+ K
Sbjct: 10 FYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKR 69
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 70 AYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-----LD 124
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 125 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 183
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ KI+F G+
Sbjct: 184 PYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGR 228
Score = 40.7 bits (91), Expect = 0.024
Identities = 17/32 (53%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++D +KR SV+ L HP+I
Sbjct: 290 KASQARDLLSKMLVIDASKRISVDEALQHPYI 321
>U09759-1|AAA74740.1| 424|Homo sapiens protein kinase protein.
Length = 424
Score = 94.3 bits (224), Expect = 2e-18
Identities = 68/234 (29%), Positives = 108/234 (46%), Gaps = 13/234 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + EL G ++F G
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQG 227
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>DQ066599-1|AAY46156.1| 424|Homo sapiens mitogen-activated protein
kinase 9 protein.
Length = 424
Score = 94.3 bits (224), Expect = 2e-18
Identities = 68/234 (29%), Positives = 108/234 (46%), Gaps = 13/234 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + EL G ++F G
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQG 227
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>CR536580-1|CAG38817.1| 424|Homo sapiens MAPK9 protein.
Length = 424
Score = 94.3 bits (224), Expect = 2e-18
Identities = 68/234 (29%), Positives = 108/234 (46%), Gaps = 13/234 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + EL G ++F G
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQG 227
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>BC032539-1|AAH32539.1| 424|Homo sapiens mitogen-activated protein
kinase 9 protein.
Length = 424
Score = 94.3 bits (224), Expect = 2e-18
Identities = 68/234 (29%), Positives = 108/234 (46%), Gaps = 13/234 (5%)
Query: 609 LTDNWDDAEGYYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR 665
++D+ D++ +Y V++ + T+ RY G G V A D K+ R
Sbjct: 1 MSDSKCDSQ-FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSR 59
Query: 666 --NNEIMHKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVL 723
N+ K REL +LK +N + +V+E + NL +V+
Sbjct: 60 PFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 119
Query: 724 KKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAA 783
+ + + + QM GI+H D+KP NI+V + LK+ DFG A
Sbjct: 120 -----HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLA 173
Query: 784 SQVTDN-EITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
N +TPY+V+R+YRAPE+ILG+ Y +D+WS C + EL G ++F G
Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQG 227
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DP KR SV+ L HP+I
Sbjct: 290 KTSQARDLLSKMLVIDPDKRISVDEALRHPYI 321
>U35005-1|AAC50611.1| 427|Homo sapiens JNK1 beta2 protein kinase
protein.
Length = 427
Score = 93.5 bits (222), Expect = 3e-18
Identities = 66/224 (29%), Positives = 101/224 (45%), Gaps = 12/224 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V IG+ T+ RY G G V A D K+ R N+ K
Sbjct: 10 FYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKR 69
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 70 AYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-----LD 124
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 125 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 183
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ G ++F G
Sbjct: 184 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPG 227
Score = 40.7 bits (91), Expect = 0.024
Identities = 17/32 (53%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++D +KR SV+ L HP+I
Sbjct: 290 KASQARDLLSKMLVIDASKRISVDEALQHPYI 321
>U35004-1|AAC50610.1| 384|Homo sapiens JNK1 beta1 protein kinase
protein.
Length = 384
Score = 93.5 bits (222), Expect = 3e-18
Identities = 66/224 (29%), Positives = 101/224 (45%), Gaps = 12/224 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V IG+ T+ RY G G V A D K+ R N+ K
Sbjct: 10 FYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKR 69
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 70 AYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-----LD 124
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 125 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 183
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ G ++F G
Sbjct: 184 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPG 227
Score = 40.7 bits (91), Expect = 0.024
Identities = 17/32 (53%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++D +KR SV+ L HP+I
Sbjct: 290 KASQARDLLSKMLVIDASKRISVDEALQHPYI 321
>BC130572-1|AAI30573.1| 427|Homo sapiens mitogen-activated protein
kinase 8 protein.
Length = 427
Score = 93.5 bits (222), Expect = 3e-18
Identities = 66/224 (29%), Positives = 101/224 (45%), Gaps = 12/224 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V IG+ T+ RY G G V A D K+ R N+ K
Sbjct: 10 FYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKR 69
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 70 AYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-----LD 124
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 125 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 183
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ G ++F G
Sbjct: 184 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPG 227
Score = 40.7 bits (91), Expect = 0.024
Identities = 17/32 (53%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++D +KR SV+ L HP+I
Sbjct: 290 KASQARDLLSKMLVIDASKRISVDEALQHPYI 321
>BC130570-1|AAI30571.1| 427|Homo sapiens mitogen-activated protein
kinase 8 protein.
Length = 427
Score = 93.5 bits (222), Expect = 3e-18
Identities = 66/224 (29%), Positives = 101/224 (45%), Gaps = 12/224 (5%)
Query: 619 YYRVRIGE---TLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKT 673
+Y V IG+ T+ RY G G V A D K+ R N+ K
Sbjct: 10 FYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKR 69
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
REL ++K +N + +V+E + NL +V++ +
Sbjct: 70 AYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-----LD 124
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEIT 792
+ + QM GI+H D+KP NI+V + LK+ DFG A T +T
Sbjct: 125 HERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMT 183
Query: 793 PYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
PY+V+R+YRAPE+ILG+ Y +D+WS C + E+ G ++F G
Sbjct: 184 PYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPG 227
Score = 40.7 bits (91), Expect = 0.024
Identities = 17/32 (53%), Positives = 24/32 (75%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++D +KR SV+ L HP+I
Sbjct: 290 KASQARDLLSKMLVIDASKRISVDEALQHPYI 321
>L29219-1|AAA61480.1| 484|Homo sapiens clk1 protein.
Length = 484
Score = 93.1 bits (221), Expect = 4e-18
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 22/249 (8%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DD EG+ + G+ L RY + G+G F VV D VAVKI++N + +
Sbjct: 143 DDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEA 202
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+++L+ LN DP +V E L ++ + +K+ G
Sbjct: 203 ARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENG-FLPFR 261
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILV---------------NENKL---NL 775
+ +R Q+ + H D+KP+NIL +E L ++
Sbjct: 262 LDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDI 321
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
K+ DFG+A+ D+E LVS R YRAPE+IL + + D+WS C + E G +F
Sbjct: 322 KVVDFGSATY--DDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVF 379
Query: 835 SGKSNNEML 843
+ E L
Sbjct: 380 PTHDSKEHL 388
>BC031549-1|AAH31549.1| 484|Homo sapiens CDC-like kinase 1 protein.
Length = 484
Score = 93.1 bits (221), Expect = 4e-18
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 22/249 (8%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DD EG+ + G+ L RY + G+G F VV D VAVKI++N + +
Sbjct: 143 DDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEA 202
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+++L+ LN DP +V E L ++ + +K+ G
Sbjct: 203 ARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENG-FLPFR 261
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILV---------------NENKL---NL 775
+ +R Q+ + H D+KP+NIL +E L ++
Sbjct: 262 LDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDI 321
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
K+ DFG+A+ D+E LVS R YRAPE+IL + + D+WS C + E G +F
Sbjct: 322 KVVDFGSATY--DDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVF 379
Query: 835 SGKSNNEML 843
+ E L
Sbjct: 380 PTHDSKEHL 388
>AC005037-5|AAY14722.1| 484|Homo sapiens unknown protein.
Length = 484
Score = 93.1 bits (221), Expect = 4e-18
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 22/249 (8%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DD EG+ + G+ L RY + G+G F VV D VAVKI++N + +
Sbjct: 143 DDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEA 202
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+++L+ LN DP +V E L ++ + +K+ G
Sbjct: 203 ARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENG-FLPFR 261
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILV---------------NENKL---NL 775
+ +R Q+ + H D+KP+NIL +E L ++
Sbjct: 262 LDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDI 321
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
K+ DFG+A+ D+E LVS R YRAPE+IL + + D+WS C + E G +F
Sbjct: 322 KVVDFGSATY--DDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVF 379
Query: 835 SGKSNNEML 843
+ E L
Sbjct: 380 PTHDSKEHL 388
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 92.3 bits (219), Expect = 8e-18
Identities = 59/222 (26%), Positives = 114/222 (51%), Gaps = 14/222 (6%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y G G+G + V++ R++ K + +++ ++ K +RE+++LK+L +
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E + + + L+ + +G+ + V+ Y Q+
Sbjct: 63 ------LVNLLEVCKKKKRWYLVFEFVDHTILDDLELFP--NGLDYQVVQKYLFQIINGI 114
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFG-AASQVTDNEI-TPYLVSRFYRAPEII 806
I+H DIKP+NILV+++ + +KLCDFG A + E+ T Y+ +R+YRAPE++
Sbjct: 115 GFCHSHNIIHRDIKPENILVSQSGV-VKLCDFGFARTLAAPGEVYTDYVATRWYRAPELL 173
Query: 807 LG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
+G V Y +D+W+ C + E+ G+ +F G S+ + L + M
Sbjct: 174 VGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIM 215
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 92.3 bits (219), Expect = 8e-18
Identities = 59/222 (26%), Positives = 114/222 (51%), Gaps = 14/222 (6%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y G G+G + V++ R++ K + +++ ++ K +RE+++LK+L +
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E + + + L+ + +G+ + V+ Y Q+
Sbjct: 63 ------LVNLLEVCKKKKRWYLVFEFVDHTILDDLELFP--NGLDYQVVQKYLFQIINGI 114
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFG-AASQVTDNEI-TPYLVSRFYRAPEII 806
I+H DIKP+NILV+++ + +KLCDFG A + E+ T Y+ +R+YRAPE++
Sbjct: 115 GFCHSHNIIHRDIKPENILVSQSGV-VKLCDFGFARTLAAPGEVYTDYVATRWYRAPELL 173
Query: 807 LG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
+G V Y +D+W+ C + E+ G+ +F G S+ + L + M
Sbjct: 174 VGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIM 215
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 92.3 bits (219), Expect = 8e-18
Identities = 59/222 (26%), Positives = 114/222 (51%), Gaps = 14/222 (6%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y G G+G + V++ R++ K + +++ ++ K +RE+++LK+L +
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E + + + L+ + +G+ + V+ Y Q+
Sbjct: 63 ------LVNLLEVCKKKKRWYLVFEFVDHTILDDLELFP--NGLDYQVVQKYLFQIINGI 114
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFG-AASQVTDNEI-TPYLVSRFYRAPEII 806
I+H DIKP+NILV+++ + +KLCDFG A + E+ T Y+ +R+YRAPE++
Sbjct: 115 GFCHSHNIIHRDIKPENILVSQSGV-VKLCDFGFARTLAAPGEVYTDYVATRWYRAPELL 173
Query: 807 LG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
+G V Y +D+W+ C + E+ G+ +F G S+ + L + M
Sbjct: 174 VGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIM 215
>AF294429-1|AAG10074.1| 481|Homo sapiens protein serine threonine
kinase Clk4 protein.
Length = 481
Score = 91.5 bits (217), Expect = 1e-17
Identities = 69/249 (27%), Positives = 106/249 (42%), Gaps = 22/249 (8%)
Query: 614 DDAEGYYRVRIGETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT 673
DD EG+ + G+ L RY + G+G F VV D VAVKI++N +
Sbjct: 141 DDEEGHLICQSGDVLRARYEIVDTLGEGAFGKVVECIDHGMDGMHVAVKIVKNVGRYREA 200
Query: 674 GLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIH 733
E+++L+ LN DP +V E L ++ + +K+
Sbjct: 201 ARSEIQVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFELLGLSTYDFIKE-NSFLPFQ 259
Query: 734 IKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILV---------------NENKL---NL 775
I +R Q+ + H D+KP+NIL +E L ++
Sbjct: 260 IDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYVVKYNSKMKRDERTLKNTDI 319
Query: 776 KLCDFGAASQVTDNEITPYLVS-RFYRAPEIILGVPYDHGIDMWSTACTIYELSTGKIMF 834
K+ DFG+A+ D+E LVS R YRAPE+IL + + D+WS C + E G +F
Sbjct: 320 KVVDFGSATY--DDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVF 377
Query: 835 SGKSNNEML 843
+ E L
Sbjct: 378 QTHDSKEHL 386
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 90.6 bits (215), Expect = 2e-17
Identities = 61/217 (28%), Positives = 107/217 (49%), Gaps = 15/217 (6%)
Query: 632 YNVYGYTGQGVFSNVVRARDQARSNTDVAVKII--RNNEIMHKTGLRELEILKRLNDADP 689
Y G G+G + V++ + + + VA+KI R + ++K +RE++ LK+ + +
Sbjct: 4 YETLGKVGEGSYGTVMKCKHK-NTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHEN- 61
Query: 690 EDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXX 749
+V E + + + L+ Y G+ K +R Y Q+
Sbjct: 62 -----LVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCH--GLESKRLRKYLFQILRAID 114
Query: 750 XXXXTGIVHADIKPDNILVNENKLNLKLCDFG-AASQVTDNEI-TPYLVSRFYRAPEIIL 807
I+H DIKP+NILV+++ + KLCDFG A + +I T Y+ +R+YRAPE++L
Sbjct: 115 YLHSNNIIHRDIKPENILVSQSGIT-KLCDFGFARTLAAPGDIYTDYVATRWYRAPELVL 173
Query: 808 -GVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
Y +D+W+ C I E++TG S+ ++L
Sbjct: 174 KDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLL 210
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 90.6 bits (215), Expect = 2e-17
Identities = 61/217 (28%), Positives = 107/217 (49%), Gaps = 15/217 (6%)
Query: 632 YNVYGYTGQGVFSNVVRARDQARSNTDVAVKII--RNNEIMHKTGLRELEILKRLNDADP 689
Y G G+G + V++ + + + VA+KI R + ++K +RE++ LK+ + +
Sbjct: 4 YETLGKVGEGSYGTVMKCKHK-NTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHEN- 61
Query: 690 EDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXX 749
+V E + + + L+ Y G+ K +R Y Q+
Sbjct: 62 -----LVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCH--GLESKRLRKYLFQILRAID 114
Query: 750 XXXXTGIVHADIKPDNILVNENKLNLKLCDFG-AASQVTDNEI-TPYLVSRFYRAPEIIL 807
I+H DIKP+NILV+++ + KLCDFG A + +I T Y+ +R+YRAPE++L
Sbjct: 115 YLHSNNIIHRDIKPENILVSQSGIT-KLCDFGFARTLAAPGDIYTDYVATRWYRAPELVL 173
Query: 808 -GVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
Y +D+W+ C I E++TG S+ ++L
Sbjct: 174 KDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLL 210
>AY065978-1|AAL40897.1| 544|Homo sapiens extracellular
signal-regulated kinase 8 protein.
Length = 544
Score = 89.4 bits (212), Expect = 5e-17
Identities = 68/230 (29%), Positives = 106/230 (46%), Gaps = 21/230 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII----RNNEIMHKTGLRELEILKRLND 686
RY + GQG + V +A D+ R+ VA+K I R+ +T RE+ +L+ D
Sbjct: 12 RYLLRRQLGQGAYGIVWKAVDR-RTGEVVAIKKIFDAFRDKTDAQRT-FREITLLQEFGD 69
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+V E + +L V++K G +H VRS Q+
Sbjct: 70 ---HPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVH---VRSIFYQLLR 123
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-------TDNEITPYLVSRF 799
+VH D KP N+L++ N +KLCDFG A + D +T Y+ +R+
Sbjct: 124 ATRFLHSGHVVHRDQKPSNVLLDAN-CTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRW 182
Query: 800 YRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMD 848
YRAPE++L Y G+DMWS C + E+ G+ +F G S L+ ++
Sbjct: 183 YRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILE 232
Score = 32.7 bits (71), Expect = 6.4
Identities = 13/27 (48%), Positives = 17/27 (62%)
Query: 931 DLLERMLMLDPAKRASVNHCLAHPFIQ 957
DLL R+L+ P KR S L HP++Q
Sbjct: 279 DLLRRLLVFAPDKRLSATQALQHPYVQ 305
>X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein
kinase protein.
Length = 496
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/212 (29%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + + + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 172 GEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 224
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ +
Sbjct: 225 TLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMH--NVKLFLFQLLRGLAYCHRQKV 282
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A + + +V+ +YR P+I+LG Y
Sbjct: 283 LHRDLKPQNLLINERG-ELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
IDMW C YE++TG+ +F G + E L +
Sbjct: 342 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF 373
>BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein
kinase 3 protein.
Length = 472
Score = 88.6 bits (210), Expect = 9e-17
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 149 GEGTYATVFKGRSKLMENL-VALKEIRLEHEEGAPCTAIREVSLLKNLKHAN------IV 201
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ I
Sbjct: 202 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHHRKI 259
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 260 LHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 318
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C YE++TG+ +F G + E L
Sbjct: 319 PIDMWGVGCIHYEMATGRPLFPGSTVKEEL 348
>BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/212 (29%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + + + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 172 GEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 224
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ +
Sbjct: 225 TLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMH--NVKLFLFQLLRGLAYCHRQKV 282
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A + + +V+ +YR P+I+LG Y
Sbjct: 283 LHRDLKPQNLLINERG-ELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
IDMW C YE++TG+ +F G + E L +
Sbjct: 342 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF 373
>BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/212 (29%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + + + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 172 GEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 224
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ +
Sbjct: 225 TLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMH--NVKLFLFQLLRGLAYCHRQKV 282
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A + + +V+ +YR P+I+LG Y
Sbjct: 283 LHRDLKPQNLLINERG-ELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
IDMW C YE++TG+ +F G + E L +
Sbjct: 342 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF 373
>BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 88.6 bits (210), Expect = 9e-17
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 149 GEGTYATVFKGRSKLMENL-VALKEIRLEHEEGAPCTAIREVSLLKNLKHAN------IV 201
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ I
Sbjct: 202 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHHRKI 259
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 260 LHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 318
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C YE++TG+ +F G + E L
Sbjct: 319 PIDMWGVGCIHYEMATGRPLFPGSTVKEEL 348
>BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein.
Length = 395
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/212 (29%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + + + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 71 GEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 123
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ +
Sbjct: 124 TLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMH--NVKLFLFQLLRGLAYCHRQKV 181
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A + + +V+ +YR P+I+LG Y
Sbjct: 182 LHRDLKPQNLLINERG-ELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 240
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
IDMW C YE++TG+ +F G + E L +
Sbjct: 241 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF 272
>BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein.
Length = 448
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/212 (29%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + + + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 124 GEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 176
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ +
Sbjct: 177 TLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMH--NVKLFLFQLLRGLAYCHRQKV 234
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A + + +V+ +YR P+I+LG Y
Sbjct: 235 LHRDLKPQNLLINERG-ELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 293
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
IDMW C YE++TG+ +F G + E L +
Sbjct: 294 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF 325
>BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/212 (29%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + + + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 172 GEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 224
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ +
Sbjct: 225 TLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMH--NVKLFLFQLLRGLAYCHRQKV 282
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A + + +V+ +YR P+I+LG Y
Sbjct: 283 LHRDLKPQNLLINERG-ELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
IDMW C YE++TG+ +F G + E L +
Sbjct: 342 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF 373
>AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase 3
isoform b protein.
Length = 504
Score = 88.6 bits (210), Expect = 9e-17
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 181 GEGTYATVFKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKNLKHAN------IV 233
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ I
Sbjct: 234 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHHRKI 291
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 292 LHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 350
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C YE++TG+ +F G + E L
Sbjct: 351 PIDMWGVGCIHYEMATGRPLFPGSTVKEEL 380
>AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase 3
isoform a protein.
Length = 474
Score = 88.6 bits (210), Expect = 9e-17
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 151 GEGTYATVFKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKNLKHAN------IV 203
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ I
Sbjct: 204 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHHRKI 261
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 262 LHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 320
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C YE++TG+ +F G + E L
Sbjct: 321 PIDMWGVGCIHYEMATGRPLFPGSTVKEEL 350
>AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 88.6 bits (210), Expect = 9e-17
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 149 GEGTYATVFKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKNLKHAN------IV 201
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ I
Sbjct: 202 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHHRKI 259
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 260 LHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 318
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C YE++TG+ +F G + E L
Sbjct: 319 PIDMWGVGCIHYEMATGRPLFPGSTVKEEL 348
>AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/212 (29%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + + + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 172 GEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 224
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ +
Sbjct: 225 TLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMH--NVKLFLFQLLRGLAYCHRQKV 282
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A + + +V+ +YR P+I+LG Y
Sbjct: 283 LHRDLKPQNLLINERG-ELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEMLKY 845
IDMW C YE++TG+ +F G + E L +
Sbjct: 342 QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF 373
>AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase 3
isoform b variant protein.
Length = 436
Score = 88.6 bits (210), Expect = 9e-17
Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 113 GEGTYATVFKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKNLKHAN------IV 165
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ I
Sbjct: 166 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHHRKI 223
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 224 LHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 282
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C YE++TG+ +F G + E L
Sbjct: 283 PIDMWGVGCIHYEMATGRPLFPGSTVKEEL 312
>X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein
kinase protein.
Length = 326
Score = 87.4 bits (207), Expect = 2e-16
Identities = 60/227 (26%), Positives = 101/227 (44%), Gaps = 8/227 (3%)
Query: 629 DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLN 685
D +Y G+G + V +ARD VA+K +R E M + +RE+ +L+ L
Sbjct: 10 DQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLE 69
Query: 686 DADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQ 743
+ + +V E + +L L K + G+ + ++ Q
Sbjct: 70 TFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPE-PGVPTETIKDMMFQ 128
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFYRA 802
+ +VH D+KP NILV + +KL DFG A + +T +V+ +YRA
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSG-QIKLADFGLARIYSFQMALTSVVVTLWYRA 187
Query: 803 PEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PE++L Y +D+WS C E+ K +F G S+ + L +D+
Sbjct: 188 PEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDV 234
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/29 (48%), Positives = 19/29 (65%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
KDLL + L +PAKR S L+HP+ Q+
Sbjct: 274 KDLLLKCLTFNPAKRISAYSALSHPYFQD 302
>BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 87.4 bits (207), Expect = 2e-16
Identities = 60/227 (26%), Positives = 101/227 (44%), Gaps = 8/227 (3%)
Query: 629 DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLN 685
D +Y G+G + V +ARD VA+K +R E M + +RE+ +L+ L
Sbjct: 10 DQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLE 69
Query: 686 DADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQ 743
+ + +V E + +L L K + G+ + ++ Q
Sbjct: 70 TFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPE-PGVPTETIKDMMFQ 128
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFYRA 802
+ +VH D+KP NILV + +KL DFG A + +T +V+ +YRA
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSG-QIKLADFGLARIYSFQMALTSVVVTLWYRA 187
Query: 803 PEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PE++L Y +D+WS C E+ K +F G S+ + L +D+
Sbjct: 188 PEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDV 234
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/29 (48%), Positives = 19/29 (65%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
KDLL + L +PAKR S L+HP+ Q+
Sbjct: 274 KDLLLKCLTFNPAKRISAYSALSHPYFQD 302
>BC051731-1|AAH51731.1| 319|Homo sapiens MAPK10 protein protein.
Length = 319
Score = 87.4 bits (207), Expect = 2e-16
Identities = 41/95 (43%), Positives = 57/95 (60%), Gaps = 2/95 (2%)
Query: 743 QMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEITPYLVSRFYR 801
QM GI+H D+KP NI+V + LK+ DFG A T +TPY+V+R+YR
Sbjct: 27 QMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMTPYVVTRYYR 85
Query: 802 APEIILGVPYDHGIDMWSTACTIYELSTGKIMFSG 836
APE+ILG+ Y +DMWS C + E+ G ++F G
Sbjct: 86 APEVILGMGYKENVDMWSVGCIMGEMIKGAVLFPG 120
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/32 (59%), Positives = 25/32 (78%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DPAKR SV+ L HP+I
Sbjct: 183 KASQARDLLSKMLVIDPAKRISVDDALQHPYI 214
>AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 87.4 bits (207), Expect = 2e-16
Identities = 60/227 (26%), Positives = 101/227 (44%), Gaps = 8/227 (3%)
Query: 629 DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLN 685
D +Y G+G + V +ARD VA+K +R E M + +RE+ +L+ L
Sbjct: 10 DQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLE 69
Query: 686 DADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQ 743
+ + +V E + +L L K + G+ + ++ Q
Sbjct: 70 TFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPE-PGVPTETIKDMMFQ 128
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFYRA 802
+ +VH D+KP NILV + +KL DFG A + +T +V+ +YRA
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSG-QIKLADFGLARIYSFQMALTSVVVTLWYRA 187
Query: 803 PEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PE++L Y +D+WS C E+ K +F G S+ + L +D+
Sbjct: 188 PEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDV 234
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/29 (48%), Positives = 19/29 (65%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
KDLL + L +PAKR S L+HP+ Q+
Sbjct: 274 KDLLLKCLTFNPAKRISAYSALSHPYFQD 302
>AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 379
Score = 86.6 bits (205), Expect = 4e-16
Identities = 56/217 (25%), Positives = 101/217 (46%), Gaps = 13/217 (5%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y TG+G + V + R++ K + + + ++ K LRE+ +LK+L +
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPN 62
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E L L++ +G+ ++S Q
Sbjct: 63 ------LVNLIEVFRRKRKMHLVFEYCDHTLLNELER--NPNGVADGVIKSVLWQTLQAL 114
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAAS-QVTDNEITPYLVSRFYRAPEIIL 807
+H DIKP+NIL+ + + +K+CDFG A + + T Y+ +R+YRAPE+++
Sbjct: 115 NFCHIHNCIHRDIKPENILITKQGI-IKICDFGFAQILIPGDAYTDYVATRWYRAPELLV 173
Query: 808 G-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
G Y +D+W+ C EL TG+ ++ GKS+ + L
Sbjct: 174 GDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQL 210
>AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 315
Score = 86.6 bits (205), Expect = 4e-16
Identities = 56/217 (25%), Positives = 101/217 (46%), Gaps = 13/217 (5%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y TG+G + V + R++ K + + + ++ K LRE+ +LK+L +
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPN 62
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E L L++ +G+ ++S Q
Sbjct: 63 ------LVNLIEVFRRKRKMHLVFEYCDHTLLNELER--NPNGVADGVIKSVLWQTLQAL 114
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAAS-QVTDNEITPYLVSRFYRAPEIIL 807
+H DIKP+NIL+ + + +K+CDFG A + + T Y+ +R+YRAPE+++
Sbjct: 115 NFCHIHNCIHRDIKPENILITKQGI-IKICDFGFAQILIPGDAYTDYVATRWYRAPELLV 173
Query: 808 G-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
G Y +D+W+ C EL TG+ ++ GKS+ + L
Sbjct: 174 GDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQL 210
>BC065516-1|AAH65516.1| 319|Homo sapiens MAPK10 protein protein.
Length = 319
Score = 86.2 bits (204), Expect = 5e-16
Identities = 41/96 (42%), Positives = 58/96 (60%), Gaps = 2/96 (2%)
Query: 743 QMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-TDNEITPYLVSRFYR 801
QM GI+H D+KP NI+V + LK+ DFG A T +TPY+V+R+YR
Sbjct: 27 QMLCGIKHLHSAGIIHRDLKPSNIVVKSD-CTLKILDFGLARTAGTSFMMTPYVVTRYYR 85
Query: 802 APEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGK 837
APE+ILG+ Y +D+WS C + E+ KI+F G+
Sbjct: 86 APEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGR 121
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/32 (59%), Positives = 25/32 (78%)
Query: 925 KISQLKDLLERMLMLDPAKRASVNHCLAHPFI 956
K SQ +DLL +ML++DPAKR SV+ L HP+I
Sbjct: 183 KASQARDLLSKMLVIDPAKRISVDDALQHPYI 214
>AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated
kinase 8 delta protein.
Length = 254
Score = 86.2 bits (204), Expect = 5e-16
Identities = 67/230 (29%), Positives = 105/230 (45%), Gaps = 21/230 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII----RNNEIMHKTGLRELEILKRLND 686
RY + GQG + V +A D+ R+ VA+K I R+ +T RE+ +L+ D
Sbjct: 12 RYLLRRQLGQGAYGIVWKAVDR-RTGEVVAIKKIFDAFRDKTDAQRT-FREITLLQEFGD 69
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+V E + +L V++K G + VRS Q+
Sbjct: 70 ---HPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVR---VRSIFYQLLR 123
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV-------TDNEITPYLVSRF 799
+VH D KP N+L++ N +KLCDFG A + D +T Y+ +R+
Sbjct: 124 ATRFLHSGHVVHRDQKPSNVLLDAN-CTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRW 182
Query: 800 YRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMD 848
YRAPE++L Y G+DMWS C + E+ G+ +F G S L+ ++
Sbjct: 183 YRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILE 232
>X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein
kinase protein.
Length = 380
Score = 85.8 bits (203), Expect = 7e-16
Identities = 63/210 (30%), Positives = 98/210 (46%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 57 GEGTYATVFKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKNLKHAN------IV 109
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ L G +H V+ + Q+ I
Sbjct: 110 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHTRKI 167
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDH 813
+H D+KP N+L+NE LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 168 LHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 226
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
I MW C YE++TG+ +F G + E L
Sbjct: 227 PIAMWGVGCIHYEMATGRPLFPGSTVKEEL 256
>X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein
kinase protein.
Length = 358
Score = 85.4 bits (202), Expect = 9e-16
Identities = 57/218 (26%), Positives = 103/218 (47%), Gaps = 14/218 (6%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y G G+G + V + R++ K + + + ++ K LRE+ +LK+L +
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E + L +Y + H+ V+S T Q
Sbjct: 64 ------LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHL--VKSITWQTLQAV 115
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT--DNEITPYLVSRFYRAPEII 806
+H D+KP+NIL+ ++ + +KLCDFG A +T + T Y+ +R+YR+PE++
Sbjct: 116 NFCHKHNCIHRDVKPENILITKHSV-IKLCDFGFARLLTGPSDYYTDYVATRWYRSPELL 174
Query: 807 LG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+G Y +D+W+ C EL +G ++ GKS+ + L
Sbjct: 175 VGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQL 212
>BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 85.4 bits (202), Expect = 9e-16
Identities = 57/218 (26%), Positives = 103/218 (47%), Gaps = 14/218 (6%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y G G+G + V + R++ K + + + ++ K LRE+ +LK+L +
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E + L +Y + H+ V+S T Q
Sbjct: 64 ------LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHL--VKSITWQTLQAV 115
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT--DNEITPYLVSRFYRAPEII 806
+H D+KP+NIL+ ++ + +KLCDFG A +T + T Y+ +R+YR+PE++
Sbjct: 116 NFCHKHNCIHRDVKPENILITKHSV-IKLCDFGFARLLTGPSDYYTDYVATRWYRSPELL 174
Query: 807 LG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+G Y +D+W+ C EL +G ++ GKS+ + L
Sbjct: 175 VGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQL 212
>AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 85.4 bits (202), Expect = 9e-16
Identities = 57/218 (26%), Positives = 103/218 (47%), Gaps = 14/218 (6%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNE--IMHKTGLRELEILKRLNDAD 688
+Y G G+G + V + R++ K + + + ++ K LRE+ +LK+L +
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPN 63
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V E + L +Y + H+ V+S T Q
Sbjct: 64 ------LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHL--VKSITWQTLQAV 115
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT--DNEITPYLVSRFYRAPEII 806
+H D+KP+NIL+ ++ + +KLCDFG A +T + T Y+ +R+YR+PE++
Sbjct: 116 NFCHKHNCIHRDVKPENILITKHSV-IKLCDFGFARLLTGPSDYYTDYVATRWYRSPELL 174
Query: 807 LG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+G Y +D+W+ C EL +G ++ GKS+ + L
Sbjct: 175 VGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQL 212
>U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein
kinase, type 4 protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/229 (28%), Positives = 100/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +ARD S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>Z95152-2|CAI19690.1| 355|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 355
Score = 84.6 bits (200), Expect = 2e-15
Identities = 66/234 (28%), Positives = 112/234 (47%), Gaps = 25/234 (10%)
Query: 617 EGYYRVRIGET---LDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIM 670
+G+Y+ + +T L Y + G G + +V A D+ RS VA+K + +EI
Sbjct: 7 KGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDK-RSGEKVAIKKLSRPFQSEIF 65
Query: 671 HKTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNS 730
K REL +LK + + +V+ + +L++++
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM------- 118
Query: 731 GIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE 790
G+ ++++ G+ D+KP N+ VNE+ LK+ DFG A D E
Sbjct: 119 GME------FSEEKIQYLVYQMLKGL--KDLKPGNLAVNED-CELKILDFGLARHA-DAE 168
Query: 791 ITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+T Y+V+R+YRAPE+IL + Y+ +D+WS C + E+ TGK +F GK + L
Sbjct: 169 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQL 222
Score = 33.1 bits (72), Expect = 4.9
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 928 QLKDLLERMLMLDPAKRASVNHCLAHPFIQ 957
Q DLLE+ML LD KR + L HPF +
Sbjct: 270 QAADLLEKMLELDVDKRLTAAQALTHPFFE 299
>CR456515-1|CAG30401.1| 357|Homo sapiens MAPK12 protein.
Length = 357
Score = 84.2 bits (199), Expect = 2e-15
Identities = 69/237 (29%), Positives = 111/237 (46%), Gaps = 24/237 (10%)
Query: 618 GYYRVRIGETLDNRYNVYGY---TGQGVFSNVVRARDQARSNTDVAVKIIRN---NEIMH 671
G+YR + +T VY G G + V A D R+ VA+K + +E+
Sbjct: 10 GFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVD-GRTGAKVAIKKLYRPFQSELFA 68
Query: 672 KTGLRELEILKRLNDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG 731
K REL +LK + + +V+ + +L +++K +
Sbjct: 69 KRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFMDFYLVMPFMGTDLGKLMK----HEK 124
Query: 732 IHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEI 791
+ ++ QM G+ D+KP N+ VNE+ LK+ DFG A Q D+E+
Sbjct: 125 LGEDRIQFLVYQMLK--------GL--RDLKPGNLAVNED-CELKILDFGLARQA-DSEM 172
Query: 792 TPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
T Y+V+R+YRAPE+IL + Y +D+WS C + E+ TGK +F G + + LK M
Sbjct: 173 TGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIM 229
>BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase 2
protein.
Length = 523
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/210 (28%), Positives = 100/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 199 GEGTYATVYKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 251
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ + G +H V+ + Q+ +
Sbjct: 252 TLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMH--NVKLFLYQILRGLAYCHRRKV 309
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILGVP-YDH 813
+H D+KP N+L+NE K LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 310 LHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST 368
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C +E+++G+ +F G + + L
Sbjct: 369 QIDMWGVGCIFFEMASGRPLFPGSTVEDEL 398
>Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase
protein.
Length = 355
Score = 83.8 bits (198), Expect = 3e-15
Identities = 65/228 (28%), Positives = 107/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D R T VA+K I ++ + LRE++IL R +
Sbjct: 17 RYTQLQYIGEGAYGMVSSAYDHVRK-TRVAIKKISPFEHQTYCQRTLREIQILLRFRHEN 75
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK + S HI + Q+
Sbjct: 76 VIGIRDILRASTLEAMRDVY-IVQDLMETDLYKLLKSQ-QLSNDHICY---FLYQILRGL 130
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A ++ D E +T Y+ +R+YRA
Sbjct: 131 KYIHSANVLHRDLKPSNLLINTT-CDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRA 188
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 189 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 236
Score = 38.3 bits (85), Expect = 0.13
Identities = 16/35 (45%), Positives = 24/35 (68%)
Query: 924 KKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
K S+ DLL+RML +P KR +V LAHP++++
Sbjct: 274 KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 308
>M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein.
Length = 366
Score = 83.8 bits (198), Expect = 3e-15
Identities = 65/228 (28%), Positives = 107/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D R T VA+K I ++ + LRE++IL R +
Sbjct: 28 RYTQLQYIGEGAYGMVSSAYDHVRK-TRVAIKKISPFEHQTYCQRTLREIQILLRFRHEN 86
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK + S HI + Q+
Sbjct: 87 VIGIRDILRASTLEAMRDVY-IVQDLMETDLYKLLKSQ-QLSNDHICY---FLYQILRGL 141
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A ++ D E +T Y+ +R+YRA
Sbjct: 142 KYIHSANVLHRDLKPSNLLINTT-CDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRA 199
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 200 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 247
Score = 38.3 bits (85), Expect = 0.13
Identities = 16/35 (45%), Positives = 24/35 (68%)
Query: 924 KKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
K S+ DLL+RML +P KR +V LAHP++++
Sbjct: 285 KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 319
>BX640648-1|CAE45794.1| 319|Homo sapiens hypothetical protein
protein.
Length = 319
Score = 83.8 bits (198), Expect = 3e-15
Identities = 41/89 (46%), Positives = 59/89 (66%), Gaps = 3/89 (3%)
Query: 760 DIKPDNILVNENKLNLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILG-VPYDHGIDMW 818
D+KP N+ VNE+ LK+ DFG A Q D+E+T Y+V+R+YRAPE+IL + Y +D+W
Sbjct: 105 DLKPGNLAVNED-CELKILDFGLARQA-DSEMTGYVVTRWYRAPEVILNWMRYTQTVDIW 162
Query: 819 STACTIYELSTGKIMFSGKSNNEMLKYFM 847
S C + E+ TGK +F G + + LK M
Sbjct: 163 SVGCIMAEMITGKTLFKGSDHLDQLKEIM 191
>BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated protein
kinase 3 protein.
Length = 379
Score = 83.8 bits (198), Expect = 3e-15
Identities = 65/228 (28%), Positives = 107/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D R T VA+K I ++ + LRE++IL R +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRK-TRVAIKKISPFEHQTYCQRTLREIQILLRFRHEN 99
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK + S HI + Q+
Sbjct: 100 VIGIRDILRASTLEAMRDVY-IVQDLMETDLYKLLKSQ-QLSNDHICY---FLYQILRGL 154
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A ++ D E +T Y+ +R+YRA
Sbjct: 155 KYIHSANVLHRDLKPSNLLINTT-CDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRA 212
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 213 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 260
Score = 38.3 bits (85), Expect = 0.13
Identities = 16/35 (45%), Positives = 24/35 (68%)
Query: 924 KKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
K S+ DLL+RML +P KR +V LAHP++++
Sbjct: 298 KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 332
>X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein.
Length = 298
Score = 83.0 bits (196), Expect = 5e-15
Identities = 62/211 (29%), Positives = 100/211 (47%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNN---EIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +AR++ VA+K IR + E + T +RE+ +LK LN +
Sbjct: 11 GEGTYGVVYKARNKLTGEV-VALKKIRXDTETEGVPSTAIREISLLKELNHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E L +L++ + +GI + ++SY Q+
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASAL-TGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+N +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T + +F G S + L
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 212
Score = 34.3 bits (75), Expect = 2.1
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
+ LL +ML DP KR S LAHPF Q+
Sbjct: 260 RSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kinase
protein.
Length = 298
Score = 83.0 bits (196), Expect = 5e-15
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +AR++ VA+K IR E + T +RE+ +LK LN +
Sbjct: 11 GEGTYGVVYKARNKLTGEV-VALKKIRLDTETEGVPSTAIREISLLKELNHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E L +L++ + +GI + ++SY Q+
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASAL-TGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+N +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T + +F G S + L
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 212
Score = 34.3 bits (75), Expect = 2.1
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
+ LL +ML DP KR S LAHPF Q+
Sbjct: 260 RSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 83.0 bits (196), Expect = 5e-15
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +AR++ VA+K IR E + T +RE+ +LK LN +
Sbjct: 11 GEGTYGVVYKARNKLTGEV-VALKKIRLDTETEGVPSTAIREISLLKELNHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E L +L++ + +GI + ++SY Q+
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASAL-TGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+N +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T + +F G S + L
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 212
Score = 34.3 bits (75), Expect = 2.1
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
+ LL +ML DP KR S LAHPF Q+
Sbjct: 260 RSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 83.0 bits (196), Expect = 5e-15
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +AR++ VA+K IR E + T +RE+ +LK LN +
Sbjct: 11 GEGTYGVVYKARNKLTGEV-VALKKIRLDTETEGVPSTAIREISLLKELNHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E L +L++ + +GI + ++SY Q+
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASAL-TGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+N +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T + +F G S + L
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 212
Score = 34.3 bits (75), Expect = 2.1
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
+ LL +ML DP KR S LAHPF Q+
Sbjct: 260 RSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 83.0 bits (196), Expect = 5e-15
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +AR++ VA+K IR E + T +RE+ +LK LN +
Sbjct: 11 GEGTYGVVYKARNKLTGEV-VALKKIRLDTETEGVPSTAIREISLLKELNHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E L +L++ + +GI + ++SY Q+
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASAL-TGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+N +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYS 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T + +F G S + L
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 212
Score = 34.3 bits (75), Expect = 2.1
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
+ LL +ML DP KR S LAHPF Q+
Sbjct: 260 RSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein
kinase protein.
Length = 523
Score = 82.6 bits (195), Expect = 6e-15
Identities = 60/210 (28%), Positives = 100/210 (47%), Gaps = 15/210 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDADPEDXXXXX 696
G+G ++ V + R + N VA+K IR + E T +RE+ +LK L A+
Sbjct: 199 GEGTYATVYKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHAN------IV 251
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V E L +L++ + G +H V+ + Q+ +
Sbjct: 252 TLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMH--NVKLFLYQILRGLAYCHRRKV 309
Query: 757 VHADIKPDNILVNENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILGVP-YDH 813
+H D+KP N+L+NE K LKL DFG A V + +V+ +YR P+++LG Y
Sbjct: 310 LHRDLKPQNLLINE-KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYLT 368
Query: 814 GIDMWSTACTIYELSTGKIMFSGKSNNEML 843
IDMW C +E+++G+ +F G + + L
Sbjct: 369 QIDMWGVGCIFFEMASGRPLFPGSTVEDEL 398
>X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein.
Length = 298
Score = 82.6 bits (195), Expect = 6e-15
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +AR++ VA+K IR E + T +RE+ +LK LN +
Sbjct: 11 GEGTYGVVYKARNKLTGEV-VALKKIRLDTETEGVPSTAIREISLLKELNHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E L +L++ + +GI + ++SY Q+
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASAL-TGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+N +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGSKYYS 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T + +F G S + L
Sbjct: 182 TAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 212
Score = 34.3 bits (75), Expect = 2.1
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 930 KDLLERMLMLDPAKRASVNHCLAHPFIQE 958
+ LL +ML DP KR S LAHPF Q+
Sbjct: 260 RSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 82.6 bits (195), Expect = 6e-15
Identities = 62/225 (27%), Positives = 105/225 (46%), Gaps = 16/225 (7%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII---RNNEIMHKTGLRELEILKRLND 686
++Y + G G+G V +A+ + VA+K + R + LRE++ L+ +
Sbjct: 2 DQYCILGRIGEGAHGIVFKAK-HVETGEIVALKKVALRRLEDGFPNQALREIKALQEM-- 58
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
ED + E + +L EV++ + + V+SY Q +
Sbjct: 59 ---EDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRP--LAQAQVKSYLQMLLK 113
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY---LVSRFYRAP 803
IVH D+KP N+L++ + LK+ DFG A + + Y + +R+YRAP
Sbjct: 114 GVAFCHANNIVHRDLKPANLLISASG-QLKIADFGLARVFSPDGSRLYTHQVATRWYRAP 172
Query: 804 EIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
E++ G YD G+D+WS C + EL G +F GK++ E L Y +
Sbjct: 173 ELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVL 217
>AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 82.6 bits (195), Expect = 6e-15
Identities = 62/225 (27%), Positives = 105/225 (46%), Gaps = 16/225 (7%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKII---RNNEIMHKTGLRELEILKRLND 686
++Y + G G+G V +A+ + VA+K + R + LRE++ L+ +
Sbjct: 2 DQYCILGRIGEGAHGIVFKAK-HVETGEIVALKKVALRRLEDGFPNQALREIKALQEM-- 58
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
ED + E + +L EV++ + + V+SY Q +
Sbjct: 59 ---EDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRP--LAQAQVKSYLQMLLK 113
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY---LVSRFYRAP 803
IVH D+KP N+L++ + LK+ DFG A + + Y + +R+YRAP
Sbjct: 114 GVAFCHANNIVHRDLKPANLLISASG-QLKIADFGLARVFSPDGSRLYTHQVATRWYRAP 172
Query: 804 EIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
E++ G YD G+D+WS C + EL G +F GK++ E L Y +
Sbjct: 173 ELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVL 217
>U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein.
Length = 816
Score = 82.2 bits (194), Expect = 8e-15
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 15/228 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNN-EIMH--KTGLRELEILKRLND 686
+ Y + G G + V AR + + VA+K I N +++ K LREL+ILK
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRL-TGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKH 111
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+ +VL+ + +L +++ + + ++ VR + Q+
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLR 168
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFY 800
++H D+KP N+LVNEN LK+ DFG A + + +T Y+ +R+Y
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
Query: 801 RAPEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
RAPE++L + Y ID+WS C E+ + +F GK+ L+ M
Sbjct: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
>U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein.
Length = 816
Score = 82.2 bits (194), Expect = 8e-15
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 15/228 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNN-EIMH--KTGLRELEILKRLND 686
+ Y + G G + V AR + + VA+K I N +++ K LREL+ILK
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRL-TGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKH 111
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+ +VL+ + +L +++ + + ++ VR + Q+
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLR 168
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFY 800
++H D+KP N+LVNEN LK+ DFG A + + +T Y+ +R+Y
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
Query: 801 RAPEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
RAPE++L + Y ID+WS C E+ + +F GK+ L+ M
Sbjct: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
>U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein.
Length = 816
Score = 82.2 bits (194), Expect = 8e-15
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 15/228 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNN-EIMH--KTGLRELEILKRLND 686
+ Y + G G + V AR + + VA+K I N +++ K LREL+ILK
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRL-TGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKH 111
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+ +VL+ + +L +++ + + ++ VR + Q+
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLR 168
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFY 800
++H D+KP N+LVNEN LK+ DFG A + + +T Y+ +R+Y
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
Query: 801 RAPEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
RAPE++L + Y ID+WS C E+ + +F GK+ L+ M
Sbjct: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
>U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein.
Length = 815
Score = 82.2 bits (194), Expect = 8e-15
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 15/228 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNN-EIMH--KTGLRELEILKRLND 686
+ Y + G G + V AR + + VA+K I N +++ K LREL+ILK
Sbjct: 52 DEYEIIETIGNGAYGVVSSARRRL-TGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKH 110
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+ +VL+ + +L +++ + + ++ VR + Q+
Sbjct: 111 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLR 167
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFY 800
++H D+KP N+LVNEN LK+ DFG A + + +T Y+ +R+Y
Sbjct: 168 GLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 226
Query: 801 RAPEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
RAPE++L + Y ID+WS C E+ + +F GK+ L+ M
Sbjct: 227 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 274
>DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein.
Length = 516
Score = 82.2 bits (194), Expect = 8e-15
Identities = 49/144 (34%), Positives = 79/144 (54%), Gaps = 8/144 (5%)
Query: 710 MVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVN 769
+V E + +L +++ S H+K + Q+ GI+H DIKP N+LVN
Sbjct: 206 VVTELMQSDLHKIIVSPQPLSSDHVKV---FLYQILRGLKYLHSAGILHRDIKPGNLLVN 262
Query: 770 ENKLNLKLCDFGAA--SQVTDN-EITPYLVSRFYRAPEIILGV-PYDHGIDMWSTACTIY 825
N + LK+CDFG A ++ ++ +T +V+++YRAPEI++G Y + ID+WS C
Sbjct: 263 SNCV-LKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFA 321
Query: 826 ELSTGKIMFSGKSNNEMLKYFMDL 849
EL +I+F +S + L DL
Sbjct: 322 ELLGRRILFQAQSPIQQLDLITDL 345
Score = 36.3 bits (80), Expect = 0.52
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 911 LAPPHHRLPLPEAKKIS-----QLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
L PH + LP +S + LL RML+ DP+KR S LAHP++ E
Sbjct: 366 LRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 418
>BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein.
Length = 515
Score = 82.2 bits (194), Expect = 8e-15
Identities = 49/144 (34%), Positives = 79/144 (54%), Gaps = 8/144 (5%)
Query: 710 MVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVN 769
+V E + +L +++ S H+K + Q+ GI+H DIKP N+LVN
Sbjct: 205 VVTELMQSDLHKIIVSPQPLSSDHVKV---FLYQILRGLKYLHSAGILHRDIKPGNLLVN 261
Query: 770 ENKLNLKLCDFGAA--SQVTDN-EITPYLVSRFYRAPEIILGV-PYDHGIDMWSTACTIY 825
N + LK+CDFG A ++ ++ +T +V+++YRAPEI++G Y + ID+WS C
Sbjct: 262 SNCV-LKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFA 320
Query: 826 ELSTGKIMFSGKSNNEMLKYFMDL 849
EL +I+F +S + L DL
Sbjct: 321 ELLGRRILFQAQSPIQQLDLITDL 344
Score = 36.3 bits (80), Expect = 0.52
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 911 LAPPHHRLPLPEAKKIS-----QLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
L PH + LP +S + LL RML+ DP+KR S LAHP++ E
Sbjct: 365 LRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 417
>BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 82.2 bits (194), Expect = 8e-15
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 15/228 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNN-EIMH--KTGLRELEILKRLND 686
+ Y + G G + V AR + + VA+K I N +++ K LREL+ILK
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRL-TGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKH 111
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+ +VL+ + +L +++ + + ++ VR + Q+
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLR 168
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFY 800
++H D+KP N+LVNEN LK+ DFG A + + +T Y+ +R+Y
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
Query: 801 RAPEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
RAPE++L + Y ID+WS C E+ + +F GK+ L+ M
Sbjct: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
>BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 82.2 bits (194), Expect = 8e-15
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 15/228 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNN-EIMH--KTGLRELEILKRLND 686
+ Y + G G + V AR + + VA+K I N +++ K LREL+ILK
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRL-TGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKH 111
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+ +VL+ + +L +++ + + ++ VR + Q+
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLR 168
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFY 800
++H D+KP N+LVNEN LK+ DFG A + + +T Y+ +R+Y
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
Query: 801 RAPEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
RAPE++L + Y ID+WS C E+ + +F GK+ L+ M
Sbjct: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
>AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated protein
kinase 7 transcript variant 5 protein.
Length = 533
Score = 82.2 bits (194), Expect = 8e-15
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 15/228 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNN-EIMH--KTGLRELEILKRLND 686
+ Y + G G + V AR + + VA+K I N +++ K LREL+ILK
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRL-TGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKH 111
Query: 687 ADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXX 746
+ +VL+ + +L +++ + + ++ VR + Q+
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLR 168
Query: 747 XXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFY 800
++H D+KP N+LVNEN LK+ DFG A + + +T Y+ +R+Y
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNEN-CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWY 227
Query: 801 RAPEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFM 847
RAPE++L + Y ID+WS C E+ + +F GK+ L+ M
Sbjct: 228 RAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIM 275
>AY033608-1|AAK52330.1| 335|Homo sapiens extracellular
signal-related kinase 1c protein.
Length = 335
Score = 82.2 bits (194), Expect = 8e-15
Identities = 66/228 (28%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D R T VA+K I ++ + LRE++IL R +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRK-TRVAIKKISPFEHQTYCQRTLREIQILLRFRHEN 99
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK + S HI + Q+
Sbjct: 100 VIGIRDILRASTLEAMRDVY-IVQDLMETDLYKLLKSQ-QLSNDHICY---FLYQILRGL 154
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L N +LK+CDFG A ++ D E +T Y+ +R+YRA
Sbjct: 155 KYIHSANVLHRDLKPSNLLSNTT-CDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRA 212
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + L
Sbjct: 213 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILAL 260
Score = 36.7 bits (81), Expect = 0.39
Identities = 14/28 (50%), Positives = 21/28 (75%)
Query: 931 DLLERMLMLDPAKRASVNHCLAHPFIQE 958
DLL+RML +P KR +V LAHP++++
Sbjct: 261 DLLDRMLTFNPNKRITVEEALAHPYLEQ 288
>AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein.
Length = 515
Score = 82.2 bits (194), Expect = 8e-15
Identities = 49/144 (34%), Positives = 79/144 (54%), Gaps = 8/144 (5%)
Query: 710 MVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVN 769
+V E + +L +++ S H+K + Q+ GI+H DIKP N+LVN
Sbjct: 205 VVTELMQSDLHKIIVSPQPLSSDHVKV---FLYQILRGLKYLHSAGILHRDIKPGNLLVN 261
Query: 770 ENKLNLKLCDFGAA--SQVTDN-EITPYLVSRFYRAPEIILGV-PYDHGIDMWSTACTIY 825
N + LK+CDFG A ++ ++ +T +V+++YRAPEI++G Y + ID+WS C
Sbjct: 262 SNCV-LKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFA 320
Query: 826 ELSTGKIMFSGKSNNEMLKYFMDL 849
EL +I+F +S + L DL
Sbjct: 321 ELLGRRILFQAQSPIQQLDLITDL 344
Score = 36.3 bits (80), Expect = 0.52
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 911 LAPPHHRLPLPEAKKIS-----QLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
L PH + LP +S + LL RML+ DP+KR S LAHP++ E
Sbjct: 365 LRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 417
>AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein.
Length = 515
Score = 82.2 bits (194), Expect = 8e-15
Identities = 49/144 (34%), Positives = 79/144 (54%), Gaps = 8/144 (5%)
Query: 710 MVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVN 769
+V E + +L +++ S H+K + Q+ GI+H DIKP N+LVN
Sbjct: 205 VVTELMQSDLHKIIVSPQPLSSDHVKV---FLYQILRGLKYLHSAGILHRDIKPGNLLVN 261
Query: 770 ENKLNLKLCDFGAA--SQVTDN-EITPYLVSRFYRAPEIILGV-PYDHGIDMWSTACTIY 825
N + LK+CDFG A ++ ++ +T +V+++YRAPEI++G Y + ID+WS C
Sbjct: 262 SNCV-LKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFA 320
Query: 826 ELSTGKIMFSGKSNNEMLKYFMDL 849
EL +I+F +S + L DL
Sbjct: 321 ELLGRRILFQAQSPIQQLDLITDL 344
Score = 36.3 bits (80), Expect = 0.52
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 911 LAPPHHRLPLPEAKKIS-----QLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
L PH + LP +S + LL RML+ DP+KR S LAHP++ E
Sbjct: 365 LRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 417
>Z48970-1|CAA88834.1| 303|Homo sapiens orf protein.
Length = 303
Score = 81.8 bits (193), Expect = 1e-14
Identities = 64/229 (27%), Positives = 99/229 (43%), Gaps = 12/229 (5%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKR 683
+RY G G + V +A D S VA+K +R + + +RE+ +L+R
Sbjct: 4 SRYEPVAEIGVGAYGTVYKACDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 684 LNDADPEDXXXXXX--XXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYT 741
L + + +V E + +LR L K G+ + ++
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDK-APPPGLPAETIKDLM 121
Query: 742 QQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVT-DNEITPYLVSRFY 800
+Q IVH D+KP+NILV +KL DFG A + +TP +V+ +Y
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGG-TVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 801 RAPEIILGVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
RAPE++L Y +DMWS C E+ K +F G S + L DL
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDL 229
>X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine
kinase protein.
Length = 379
Score = 81.8 bits (193), Expect = 1e-14
Identities = 65/228 (28%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D R T VA+K I ++ + LRE++IL R +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRK-TRVAIKKISPFEHQTYCQRTLREIQILLRFRHEN 99
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK + S HI + Q+
Sbjct: 100 VIGIRDILRASTLEAMRDVY-IVQDLMETDLYKLLKSQ-QLSNDHICY---FLYQILRGL 154
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L N +LK+CDFG A ++ D E +T Y+ +R+YRA
Sbjct: 155 KYIHSANVLHRDLKPSNLLSNTT-CDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRA 212
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 213 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 260
Score = 38.3 bits (85), Expect = 0.13
Identities = 16/35 (45%), Positives = 24/35 (68%)
Query: 924 KKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
K S+ DLL+RML +P KR +V LAHP++++
Sbjct: 298 KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 332
>AY033607-1|AAK52329.1| 357|Homo sapiens extracellular
signal-related kinase 1b protein.
Length = 357
Score = 81.8 bits (193), Expect = 1e-14
Identities = 65/228 (28%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D R T VA+K I ++ + LRE++IL R +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRK-TRVAIKKISPFEHQTYCQRTLREIQILLRFRHEN 99
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK + S HI + Q+
Sbjct: 100 VIGIRDILRASTLEAMRDVY-IVQDLMETDLYKLLKSQ-QLSNDHICY---FLYQILRGL 154
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L N +LK+CDFG A ++ D E +T Y+ +R+YRA
Sbjct: 155 KYIHSANVLHRDLKPSNLLSNTT-CDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRA 212
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 213 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 260
Score = 38.3 bits (85), Expect = 0.13
Identities = 16/35 (45%), Positives = 24/35 (68%)
Query: 924 KKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
K S+ DLL+RML +P KR +V LAHP++++
Sbjct: 298 KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 332
>BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein.
Length = 277
Score = 81.4 bits (192), Expect = 1e-14
Identities = 47/139 (33%), Positives = 72/139 (51%), Gaps = 12/139 (8%)
Query: 718 NLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKL 777
+L V++K G +H VRS Q+ +VH D KP N+L++ N +KL
Sbjct: 115 DLNAVIRKGGLLQDVH---VRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDAN-CTVKL 170
Query: 778 CDFGAASQV-------TDNEITPYLVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELST 829
CDFG A + D +T Y+ +R+YRAPE++L Y G+DMWS C + E+
Sbjct: 171 CDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLR 230
Query: 830 GKIMFSGKSNNEMLKYFMD 848
G+ +F G S L+ ++
Sbjct: 231 GRPLFPGTSTLHQLELILE 249
>Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein
kinase protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinase
(CAK) protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase
protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase
protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine
kinase protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHRHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase 7
protein.
Length = 346
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 21/223 (9%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR------NNEIMHKTGLRELEILKRL 684
RY + G+G F+ V +ARD+ +N VA+K I+ + +++T LRE+++L+ L
Sbjct: 11 RYEKLDFLGEGQFATVYKARDK-NTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 685 NDADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKAVRSYTQQ 743
+ + +V + + +L ++K + HIKA T Q
Sbjct: 70 SHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 744 MXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQV--TDNEITPYLVSRFYR 801
I+H D+KP+N+L++EN + LKL DFG A + T +V+R+YR
Sbjct: 124 ---GLEYLHQHWILHRDLKPNNLLLDENGV-LKLADFGLAKSFGSPNRAYTHQVVTRWYR 179
Query: 802 APEIILGV-PYDHGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
APE++ G Y G+DMW+ C + EL G S+ + L
Sbjct: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 222
>Z25435-1|CAA80922.1| 46|Homo sapiens protein-serine/threonine
kinase protein.
Length = 46
Score = 80.2 bits (189), Expect = 3e-14
Identities = 35/44 (79%), Positives = 39/44 (88%)
Query: 776 KLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWS 819
KL DFG+AS V DN+ITPYLVSRFYRAPEII+G YD+GIDMWS
Sbjct: 1 KLGDFGSASHVADNDITPYLVSRFYRAPEIIIGKSYDYGIDMWS 44
>BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein.
Length = 324
Score = 80.2 bits (189), Expect = 3e-14
Identities = 66/232 (28%), Positives = 111/232 (47%), Gaps = 23/232 (9%)
Query: 625 GETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEIL 681
G+ +++++ G G+G + V +ARD+ VA+K +R E T +RE++IL
Sbjct: 84 GKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEM-VALKKVRLDNEKEGFPITAIREIKIL 142
Query: 682 KRLNDAD----PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG-IHIKA 736
++L E +V E + +L +L+ SG +H
Sbjct: 143 RQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLE-----SGLVHFNE 197
Query: 737 --VRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY 794
++S+ +Q+ +H DIK NIL+N N+ +KL DFG A + E PY
Sbjct: 198 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSEESRPY 256
Query: 795 ---LVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEM 842
+++ +YR PE++LG Y ID+WS C + EL T K +F ++N E+
Sbjct: 257 TNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF--QANQEL 306
>AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-like
5 (cholinesterase-related cell division controller)
protein.
Length = 1512
Score = 80.2 bits (189), Expect = 3e-14
Identities = 66/232 (28%), Positives = 111/232 (47%), Gaps = 23/232 (9%)
Query: 625 GETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEIL 681
G+ +++++ G G+G + V +ARD+ VA+K +R E T +RE++IL
Sbjct: 698 GKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEM-VALKKVRLDNEKEGFPITAIREIKIL 756
Query: 682 KRLNDAD----PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG-IHIKA 736
++L E +V E + +L +L+ SG +H
Sbjct: 757 RQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLE-----SGLVHFNE 811
Query: 737 --VRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY 794
++S+ +Q+ +H DIK NIL+N N+ +KL DFG A + E PY
Sbjct: 812 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSEESRPY 870
Query: 795 ---LVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEM 842
+++ +YR PE++LG Y ID+WS C + EL T K +F ++N E+
Sbjct: 871 TNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF--QANQEL 920
>AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1452
Score = 80.2 bits (189), Expect = 3e-14
Identities = 66/232 (28%), Positives = 111/232 (47%), Gaps = 23/232 (9%)
Query: 625 GETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEIL 681
G+ +++++ G G+G + V +ARD+ VA+K +R E T +RE++IL
Sbjct: 698 GKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEM-VALKKVRLDNEKEGFPITAIREIKIL 756
Query: 682 KRLNDAD----PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG-IHIKA 736
++L E +V E + +L +L+ SG +H
Sbjct: 757 RQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLE-----SGLVHFNE 811
Query: 737 --VRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY 794
++S+ +Q+ +H DIK NIL+N N+ +KL DFG A + E PY
Sbjct: 812 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSEESRPY 870
Query: 795 ---LVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEM 842
+++ +YR PE++LG Y ID+WS C + EL T K +F ++N E+
Sbjct: 871 TNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF--QANQEL 920
>AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1512
Score = 80.2 bits (189), Expect = 3e-14
Identities = 66/232 (28%), Positives = 111/232 (47%), Gaps = 23/232 (9%)
Query: 625 GETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEIL 681
G+ +++++ G G+G + V +ARD+ VA+K +R E T +RE++IL
Sbjct: 698 GKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEM-VALKKVRLDNEKEGFPITAIREIKIL 756
Query: 682 KRLNDAD----PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSG-IHIKA 736
++L E +V E + +L +L+ SG +H
Sbjct: 757 RQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLE-----SGLVHFNE 811
Query: 737 --VRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY 794
++S+ +Q+ +H DIK NIL+N N+ +KL DFG A + E PY
Sbjct: 812 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSEESRPY 870
Query: 795 ---LVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEM 842
+++ +YR PE++LG Y ID+WS C + EL T K +F ++N E+
Sbjct: 871 TNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF--QANQEL 920
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 79.8 bits (188), Expect = 4e-14
Identities = 62/211 (29%), Positives = 100/211 (47%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNN---EIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +A+++ VA+K IR + E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKAKNRETGQL-VALKKIRLDLEMEGVPSTAIREISLLKELKHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E LS +L++ + S + + ++SY Q+
Sbjct: 64 VRLLDVVHNERKLYLVFEFLSQDLKKYMDST-PGSELPLHLIKSYLFQLLQGVSFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+NE +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VIHRDLKPQNLLINELGA-IKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYT 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T K +F G S + L
Sbjct: 182 TAVDIWSIGCIFAEMVTRKALFPGDSEIDQL 212
>M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kinase
protein.
Length = 418
Score = 79.8 bits (188), Expect = 4e-14
Identities = 63/229 (27%), Positives = 109/229 (47%), Gaps = 17/229 (7%)
Query: 625 GETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEIL 681
G+ +++++ G G+G + V +ARD+ VA+K +R E T +RE++IL
Sbjct: 84 GKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEM-VALKKVRLDNEKEGFPITAIREIKIL 142
Query: 682 KRLNDAD----PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAV 737
++L E +V E + +L +L+ + + +
Sbjct: 143 RQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH--FYENHI 200
Query: 738 RSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY--- 794
+S+ +Q+ +H DIK NIL+N N+ +KL DFG A + E PY
Sbjct: 201 KSFMRQLMEGLDYCHKKNFLHRDIKCSNILLN-NRGQIKLADFGLARLYSSEESRPYTNK 259
Query: 795 LVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEM 842
+++ +YR PE++LG Y ID+WS C + EL T K +F ++N E+
Sbjct: 260 VITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF--QANQEL 306
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 79.8 bits (188), Expect = 4e-14
Identities = 62/211 (29%), Positives = 100/211 (47%), Gaps = 15/211 (7%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNN---EIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V +A+++ VA+K IR + E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKAKNRETGQL-VALKKIRLDLEMEGVPSTAIREISLLKELKHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
+V E LS +L++ + S + + ++SY Q+
Sbjct: 64 VRLLDVVHNERKLYLVFEFLSQDLKKYMDST-PGSELPLHLIKSYLFQLLQGVSFCHSHR 122
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILGVP-YD 812
++H D+KP N+L+NE +KL DFG A V T +V+ +YRAPEI+LG Y
Sbjct: 123 VIHRDLKPQNLLINELGA-IKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYT 181
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS C E+ T K +F G S + L
Sbjct: 182 TAVDIWSIGCIFAEMVTRKALFPGDSEIDQL 212
>U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein
kinase protein.
Length = 229
Score = 79.4 bits (187), Expect = 6e-14
Identities = 47/141 (33%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Query: 710 MVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVN 769
+V E + +LR L K G+ + ++ +Q IVH D+KP+NILV
Sbjct: 17 LVFEHVDQDLRTYLDK-APPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVT 75
Query: 770 ENKLNLKLCDFGAASQVT-DNEITPYLVSRFYRAPEIILGVPYDHGIDMWSTACTIYELS 828
+KL DFG A + +TP +V+ +YRAPE++L Y +DMWS C E+
Sbjct: 76 SGG-TVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMF 134
Query: 829 TGKIMFSGKSNNEMLKYFMDL 849
K +F G S + L DL
Sbjct: 135 RRKPLFCGNSEADQLGKIFDL 155
>Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycle
control gene CDC2. ).
Length = 297
Score = 79.0 bits (186), Expect = 7e-14
Identities = 59/211 (27%), Positives = 97/211 (45%), Gaps = 14/211 (6%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V + R + VA+K IR E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKGRHKTTGQV-VAMKKIRLESEEEGVPSTAIREISLLKELRHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
++ E LSM+L++ L + V+SY Q+
Sbjct: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILG-VPYD 812
++H D+KP N+L+ ++K +KL DFG A + T +V+ +YR+PE++LG Y
Sbjct: 124 VLHRDLKPQNLLI-DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS EL+T K +F G S + L
Sbjct: 183 TPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/28 (50%), Positives = 18/28 (64%)
Query: 931 DLLERMLMLDPAKRASVNHCLAHPFIQE 958
DLL +ML+ DPAKR S L HP+ +
Sbjct: 262 DLLSKMLIYDPAKRISGKMALNHPYFND 289
>X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene
involved in cell cycle control. ).
Length = 297
Score = 79.0 bits (186), Expect = 7e-14
Identities = 59/211 (27%), Positives = 97/211 (45%), Gaps = 14/211 (6%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V + R + VA+K IR E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKGRHKTTGQV-VAMKKIRLESEEEGVPSTAIREISLLKELRHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
++ E LSM+L++ L + V+SY Q+
Sbjct: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILG-VPYD 812
++H D+KP N+L+ ++K +KL DFG A + T +V+ +YR+PE++LG Y
Sbjct: 124 VLHRDLKPQNLLI-DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS EL+T K +F G S + L
Sbjct: 183 TPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/28 (50%), Positives = 18/28 (64%)
Query: 931 DLLERMLMLDPAKRASVNHCLAHPFIQE 958
DLL +ML+ DPAKR S L HP+ +
Sbjct: 262 DLLSKMLIYDPAKRISGKMALNHPYFND 289
>BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 79.0 bits (186), Expect = 7e-14
Identities = 59/211 (27%), Positives = 97/211 (45%), Gaps = 14/211 (6%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V + R + VA+K IR E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKGRHKTTGQV-VAMKKIRLESEEEGVPSTAIREISLLKELRHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
++ E LSM+L++ L + V+SY Q+
Sbjct: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILG-VPYD 812
++H D+KP N+L+ ++K +KL DFG A + T +V+ +YR+PE++LG Y
Sbjct: 124 VLHRDLKPQNLLI-DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS EL+T K +F G S + L
Sbjct: 183 TPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/28 (50%), Positives = 18/28 (64%)
Query: 931 DLLERMLMLDPAKRASVNHCLAHPFIQE 958
DLL +ML+ DPAKR S L HP+ +
Sbjct: 262 DLLSKMLIYDPAKRISGKMALNHPYFND 289
>BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein.
Length = 225
Score = 79.0 bits (186), Expect = 7e-14
Identities = 59/211 (27%), Positives = 97/211 (45%), Gaps = 14/211 (6%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V + R + VA+K IR E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKGRHKTTGQV-VAMKKIRLESEEEGVPSTAIREISLLKELRHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
++ E LSM+L++ L + V+SY Q+
Sbjct: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILG-VPYD 812
++H D+KP N+L+ ++K +KL DFG A + T +V+ +YR+PE++LG Y
Sbjct: 124 VLHRDLKPQNLLI-DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS EL+T K +F G S + L
Sbjct: 183 TPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
>BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 79.0 bits (186), Expect = 7e-14
Identities = 59/211 (27%), Positives = 97/211 (45%), Gaps = 14/211 (6%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V + R + VA+K IR E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKGRHKTTGQV-VAMKKIRLESEEEGVPSTAIREISLLKELRHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
++ E LSM+L++ L + V+SY Q+
Sbjct: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILG-VPYD 812
++H D+KP N+L+ ++K +KL DFG A + T +V+ +YR+PE++LG Y
Sbjct: 124 VLHRDLKPQNLLI-DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS EL+T K +F G S + L
Sbjct: 183 TPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/28 (50%), Positives = 18/28 (64%)
Query: 931 DLLERMLMLDPAKRASVNHCLAHPFIQE 958
DLL +ML+ DPAKR S L HP+ +
Sbjct: 262 DLLSKMLIYDPAKRISGKMALNHPYFND 289
>AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 79.0 bits (186), Expect = 7e-14
Identities = 59/211 (27%), Positives = 97/211 (45%), Gaps = 14/211 (6%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLNDADPEDXXXX 695
G+G + V + R + VA+K IR E + T +RE+ +LK L +
Sbjct: 11 GEGTYGVVYKGRHKTTGQV-VAMKKIRLESEEEGVPSTAIREISLLKELRHPN------I 63
Query: 696 XXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTG 755
++ E LSM+L++ L + V+SY Q+
Sbjct: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
Query: 756 IVHADIKPDNILVNENKLNLKLCDFGAASQ--VTDNEITPYLVSRFYRAPEIILG-VPYD 812
++H D+KP N+L+ ++K +KL DFG A + T +V+ +YR+PE++LG Y
Sbjct: 124 VLHRDLKPQNLLI-DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 813 HGIDMWSTACTIYELSTGKIMFSGKSNNEML 843
+D+WS EL+T K +F G S + L
Sbjct: 183 TPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
Score = 33.1 bits (72), Expect = 4.9
Identities = 14/28 (50%), Positives = 18/28 (64%)
Query: 931 DLLERMLMLDPAKRASVNHCLAHPFIQE 958
DLL +ML+ DPAKR S L HP+ +
Sbjct: 262 DLLSKMLIYDPAKRISGKMALNHPYFND 289
>BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein.
Length = 292
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 14/213 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT--GLRELEILKRLNDA 687
NRY G G + +V+ R S +A+K ++ + LRE++ LK+LN A
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRS-IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
Query: 688 DPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXX 747
+ + E + NL +++K+ +N A+R+ Q+
Sbjct: 61 N------VVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQG 112
Query: 748 XXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEII 806
G H D+KP+N+L +L +K+ DFG A ++ T Y+ +R+YRAPE++
Sbjct: 113 LAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL 171
Query: 807 L-GVPYDHGIDMWSTACTIYELSTGKIMFSGKS 838
L Y ID+W+ C + E+ T + +F G S
Sbjct: 172 LRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGAS 204
>AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 14/213 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT--GLRELEILKRLNDA 687
NRY G G + +V+ R S +A+K ++ + LRE++ LK+LN A
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRS-IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
Query: 688 DPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXX 747
+ + E + NL +++K+ +N A+R+ Q+
Sbjct: 61 N------VVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQG 112
Query: 748 XXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEII 806
G H D+KP+N+L +L +K+ DFG A ++ T Y+ +R+YRAPE++
Sbjct: 113 LAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL 171
Query: 807 L-GVPYDHGIDMWSTACTIYELSTGKIMFSGKS 838
L Y ID+W+ C + E+ T + +F G S
Sbjct: 172 LRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGAS 204
>AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 14/213 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT--GLRELEILKRLNDA 687
NRY G G + +V+ R S +A+K ++ + LRE++ LK+LN A
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRS-IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
Query: 688 DPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXX 747
+ + E + NL +++K+ +N A+R+ Q+
Sbjct: 61 N------VVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQG 112
Query: 748 XXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEII 806
G H D+KP+N+L +L +K+ DFG A ++ T Y+ +R+YRAPE++
Sbjct: 113 LAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL 171
Query: 807 L-GVPYDHGIDMWSTACTIYELSTGKIMFSGKS 838
L Y ID+W+ C + E+ T + +F G S
Sbjct: 172 LRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGAS 204
>AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase
protein.
Length = 632
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 14/213 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT--GLRELEILKRLNDA 687
NRY G G + +V+ R S +A+K ++ + LRE++ LK+LN A
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRS-IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
Query: 688 DPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXX 747
+ + E + NL +++K+ +N A+R+ Q+
Sbjct: 61 N------VVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQG 112
Query: 748 XXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEII 806
G H D+KP+N+L +L +K+ DFG A ++ T Y+ +R+YRAPE++
Sbjct: 113 LAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL 171
Query: 807 L-GVPYDHGIDMWSTACTIYELSTGKIMFSGKS 838
L Y ID+W+ C + E+ T + +F G S
Sbjct: 172 LRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGAS 204
>AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein.
Length = 640
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 14/213 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKT--GLRELEILKRLNDA 687
NRY G G + +V+ R S +A+K ++ + LRE++ LK+LN A
Sbjct: 10 NRYTTIRQLGDGTYGSVLLGRS-IESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 68
Query: 688 DPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXX 747
+ + E + NL +++K+ +N A+R+ Q+
Sbjct: 69 N------VVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQG 120
Query: 748 XXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEII 806
G H D+KP+N+L +L +K+ DFG A ++ T Y+ +R+YRAPE++
Sbjct: 121 LAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL 179
Query: 807 L-GVPYDHGIDMWSTACTIYELSTGKIMFSGKS 838
L Y ID+W+ C + E+ T + +F G S
Sbjct: 180 LRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGAS 212
>AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase
alpha SV9 isoform protein.
Length = 755
Score = 77.4 bits (182), Expect = 2e-13
Identities = 85/348 (24%), Positives = 145/348 (41%), Gaps = 20/348 (5%)
Query: 509 QNATASPFSPQSQRSVSPTSKNKSHDHKEKNKEERKHIRTETRSETLIKKIENESKSTIK 568
Q+ + S S S S S + S + +E+ +EE + T SE ++ E E + T
Sbjct: 280 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET-- 337
Query: 569 LQKSNKDSEWDMFADQDNFDSVDTPTTGDSKTKLATENPSLTDNWDDAEGYYRVRIGETL 628
SN + + A++ + + + +++ L S D D E G
Sbjct: 338 --GSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR-DSGESEEAEEEGCRS 394
Query: 629 DNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEILKRLN 685
+ +G + V RA+D+ +++ VA+K ++ E T LRE+ + +
Sbjct: 395 VEEFQCLNRIEEGTYGVVYRAKDK-KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 453
Query: 686 DADPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMX 745
+ V L +L E +K+ V++ Q+
Sbjct: 454 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLK-SLMETMKQPFLPG-----EVKTLMIQLL 507
Query: 746 XXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTD--NEITPYLVSRFYRAP 803
I+H D+K N+L++ + LK+ DFG A + TP +V+ +YRAP
Sbjct: 508 RGVKHLHDNWILHRDLKTSNLLLSHAGI-LKVGDFGLAREYGSPLKAYTPVVVTLWYRAP 566
Query: 804 EIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSN-NEMLKYFMDL 849
E++LG Y +DMWS C EL T K +F GKS +++ K F DL
Sbjct: 567 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDL 614
>BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein.
Length = 283
Score = 77.0 bits (181), Expect = 3e-13
Identities = 46/137 (33%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
Query: 710 MVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGIVHADIKPDNILVN 769
+V E L +L++ L G +H V+ + Q+ I+H D+KP N+L+N
Sbjct: 26 LVFEYLDSDLKQYLDHCGNLMSMH--NVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLIN 83
Query: 770 ENKLNLKLCDFGAA--SQVTDNEITPYLVSRFYRAPEIILG-VPYDHGIDMWSTACTIYE 826
E LKL DFG A V + +V+ +YR P+++LG Y IDMW C YE
Sbjct: 84 ERG-ELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYE 142
Query: 827 LSTGKIMFSGKSNNEML 843
++TG+ +F G + E L
Sbjct: 143 MATGRPLFPGSTVKEEL 159
>AL833829-1|CAD38689.1| 893|Homo sapiens hypothetical protein
protein.
Length = 893
Score = 77.0 bits (181), Expect = 3e-13
Identities = 37/86 (43%), Positives = 54/86 (62%), Gaps = 3/86 (3%)
Query: 763 PDNILVNE---NKLNLKLCDFGAASQVTDNEITPYLVSRFYRAPEIILGVPYDHGIDMWS 819
P+NI++ + +K+ DFG+AS V+ + YL SR+YRAPEIILG+P+ IDMWS
Sbjct: 1 PENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWS 60
Query: 820 TACTIYELSTGKIMFSGKSNNEMLKY 845
C I EL G ++ G S + ++Y
Sbjct: 61 LGCVIAELFLGWPLYPGASEYDQIRY 86
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 77.0 bits (181), Expect = 3e-13
Identities = 65/222 (29%), Positives = 103/222 (46%), Gaps = 17/222 (7%)
Query: 625 GETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEIL 681
G+ +++++ G G+G + V +ARD+ VA+K +R E T +RE++IL
Sbjct: 720 GKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEL-VALKKVRLDNEKEGFPITAIREIKIL 778
Query: 682 KRLNDAD----PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKA 736
++L E +V E + +L +L+ + S HIK
Sbjct: 779 RQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIK- 837
Query: 737 VRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY-- 794
S+ +Q+ +H DIK NIL+N N +KL DFG A E PY
Sbjct: 838 --SFMKQLMEGLEYCHKKNFLHRDIKCSNILLN-NSGQIKLADFGLARLYNSEESRPYTN 894
Query: 795 -LVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMF 834
+++ +YR PE++LG Y ID+WS C + EL T K +F
Sbjct: 895 KVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF 936
>AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase
protein.
Length = 632
Score = 77.0 bits (181), Expect = 3e-13
Identities = 57/213 (26%), Positives = 99/213 (46%), Gaps = 14/213 (6%)
Query: 630 NRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGL--RELEILKRLNDA 687
NRY G G + +V+ R S +A+K ++ + + RE++ LK+LN A
Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRS-IESGELIAIKKMKRKFYSWEECMNQREVKSLKKLNHA 60
Query: 688 DPEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXX 747
+ + E + NL +++K+ +N A+R+ Q+
Sbjct: 61 N------VVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQG 112
Query: 748 XXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE-ITPYLVSRFYRAPEII 806
G H D+KP+N+L +L +K+ DFG A ++ T Y+ +R+YRAPE++
Sbjct: 113 LAFIHKLGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRWYRAPEVL 171
Query: 807 L-GVPYDHGIDMWSTACTIYELSTGKIMFSGKS 838
L Y ID+W+ C + E+ T + +F G S
Sbjct: 172 LRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGAS 204
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 77.0 bits (181), Expect = 3e-13
Identities = 57/219 (26%), Positives = 93/219 (42%), Gaps = 19/219 (8%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGL--RELEILKRLNDADPEDXXXXX 696
G G F+ V + R + + + +VAVK I + L +E++ILK L +
Sbjct: 23 GHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHEN------IV 76
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V+E N ++ + +R + QQ+ GI
Sbjct: 77 ALYDFQEMANSVYLVME--YCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGI 134
Query: 757 VHADIKPDNILV--------NENKLNLKLCDFGAASQVTDNEITPYLV-SRFYRAPEIIL 807
+H D+KP NIL+ N N + +K+ DFG A + N + L S Y APE+I+
Sbjct: 135 IHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIM 194
Query: 808 GVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYF 846
YD D+WS +Y+ TGK F S ++ ++
Sbjct: 195 SQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFY 233
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 77.0 bits (181), Expect = 3e-13
Identities = 57/219 (26%), Positives = 93/219 (42%), Gaps = 19/219 (8%)
Query: 639 GQGVFSNVVRARDQARSNTDVAVKIIRNNEIMHKTGL--RELEILKRLNDADPEDXXXXX 696
G G F+ V + R + + + +VAVK I + L +E++ILK L +
Sbjct: 39 GHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHEN------IV 92
Query: 697 XXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXXXXXXXTGI 756
+V+E N ++ + +R + QQ+ GI
Sbjct: 93 ALYDFQEMANSVYLVME--YCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGI 150
Query: 757 VHADIKPDNILV--------NENKLNLKLCDFGAASQVTDNEITPYLV-SRFYRAPEIIL 807
+H D+KP NIL+ N N + +K+ DFG A + N + L S Y APE+I+
Sbjct: 151 IHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIM 210
Query: 808 GVPYDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYF 846
YD D+WS +Y+ TGK F S ++ ++
Sbjct: 211 SQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFY 249
>Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase
protein.
Length = 348
Score = 76.2 bits (179), Expect = 5e-13
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D + VA+K I ++ + LRE++IL R +
Sbjct: 12 RYTNLSYIGEGAYGMVCSAYDNV-NKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHEN 70
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK ++ HI + Q+
Sbjct: 71 IIGINDIIRAPTIEQMKDVY-IVQDLMETDLYKLLKTQHLSND-HICY---FLYQILRGL 125
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A +V D + +T Y+ +R+YRA
Sbjct: 126 KYIHSANVLHRDLKPSNLLLNTT-CDLKICDFGLA-RVADPDHDHTGFLTEYVATRWYRA 183
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 184 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 231
Score = 36.3 bits (80), Expect = 0.52
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 914 PHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
P +RL P A S+ DLL++ML +P KR V LAHP++++
Sbjct: 262 PWNRL-FPNAD--SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 303
>Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein.
Length = 360
Score = 76.2 bits (179), Expect = 5e-13
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D + VA+K I ++ + LRE++IL R +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNV-NKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHEN 82
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK ++ HI + Q+
Sbjct: 83 IIGINDIIQAPTIEQMKDVY-IVQDLMETDLYKLLKTQHLSND-HICY---FLYQILRGL 137
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A +V D + +T Y+ +R+YRA
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTT-CDLKICDFGLA-RVADPDHDHTGFLTEYVATRWYRA 195
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 196 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 243
Score = 36.3 bits (80), Expect = 0.52
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 914 PHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
P +RL P A S+ DLL++ML +P KR V LAHP++++
Sbjct: 274 PWNRL-FPNAD--SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein.
Length = 360
Score = 76.2 bits (179), Expect = 5e-13
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D + VA+K I ++ + LRE++IL R +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNV-NKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHEN 82
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK ++ HI + Q+
Sbjct: 83 IIGINDIIRAPTIEQMKDVY-IVQDLMETDLYKLLKTQHLSND-HICY---FLYQILRGL 137
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A +V D + +T Y+ +R+YRA
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTT-CDLKICDFGLA-RVADPDHDHTGFLTEYVATRWYRA 195
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 196 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 243
Score = 36.3 bits (80), Expect = 0.52
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 914 PHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
P +RL P A S+ DLL++ML +P KR V LAHP++++
Sbjct: 274 PWNRL-FPNAD--SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 76.2 bits (179), Expect = 5e-13
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D + VA+K I ++ + LRE++IL R +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNV-NKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHEN 82
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK ++ HI + Q+
Sbjct: 83 IIGINDIIRAPTIEQMKDVY-IVQDLMETDLYKLLKTQHLSND-HICY---FLYQILRGL 137
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A +V D + +T Y+ +R+YRA
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTT-CDLKICDFGLA-RVADPDHDHTGFLTEYVATRWYRA 195
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 196 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 243
Score = 36.3 bits (80), Expect = 0.52
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 914 PHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
P +RL P A S+ DLL++ML +P KR V LAHP++++
Sbjct: 274 PWNRL-FPNAD--SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 76.2 bits (179), Expect = 5e-13
Identities = 62/228 (27%), Positives = 106/228 (46%), Gaps = 17/228 (7%)
Query: 631 RYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR--NNEIMHKTGLRELEILKRLNDAD 688
RY Y G+G + V A D + VA+K I ++ + LRE++IL R +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNV-NKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHEN 82
Query: 689 PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKNSGIHIKAVRSYTQQMXXXX 748
+V + + +L ++LK ++ HI + Q+
Sbjct: 83 IIGINDIIRAPTIEQMKDVY-IVQDLMETDLYKLLKTQHLSND-HICY---FLYQILRGL 137
Query: 749 XXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNE------ITPYLVSRFYRA 802
++H D+KP N+L+N +LK+CDFG A +V D + +T Y+ +R+YRA
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTT-CDLKICDFGLA-RVADPDHDHTGFLTEYVATRWYRA 195
Query: 803 PEIILGVP-YDHGIDMWSTACTIYELSTGKIMFSGKSNNEMLKYFMDL 849
PEI+L Y ID+WS C + E+ + + +F GK + L + + +
Sbjct: 196 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGI 243
Score = 36.3 bits (80), Expect = 0.52
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 914 PHHRLPLPEAKKISQLKDLLERMLMLDPAKRASVNHCLAHPFIQE 958
P +RL P A S+ DLL++ML +P KR V LAHP++++
Sbjct: 274 PWNRL-FPNAD--SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 75.8 bits (178), Expect = 7e-13
Identities = 64/222 (28%), Positives = 103/222 (46%), Gaps = 17/222 (7%)
Query: 625 GETLDNRYNVYGYTGQGVFSNVVRARDQARSNTDVAVKIIR---NNEIMHKTGLRELEIL 681
G+ +++++ G G+G + V +A+D+ VA+K +R E T +RE++IL
Sbjct: 774 GKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGEL-VALKKVRLDNEKEGFPITAIREIKIL 832
Query: 682 KRLNDAD----PEDXXXXXXXXXXXXXXXXXXMVLEPLSMNLREVLKKYGKN-SGIHIKA 736
++L E +V E + +L +L+ + S HIK
Sbjct: 833 RQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIK- 891
Query: 737 VRSYTQQMXXXXXXXXXTGIVHADIKPDNILVNENKLNLKLCDFGAASQVTDNEITPY-- 794
S+ +Q+ +H DIK NIL+N N +KL DFG A E PY
Sbjct: 892 --SFMKQLMEGLEYCHKKNFLHRDIKCSNILLN-NSGQIKLADFGLARLYNSEESRPYTN 948
Query: 795 -LVSRFYRAPEIILGVP-YDHGIDMWSTACTIYELSTGKIMF 834
+++ +YR PE++LG Y ID+WS C + EL T K +F
Sbjct: 949 KVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF 990
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.312 0.129 0.364
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,280,134
Number of Sequences: 224733
Number of extensions: 3484569
Number of successful extensions: 18336
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 958
Number of HSP's successfully gapped in prelim test: 1365
Number of HSP's that attempted gapping in prelim test: 13593
Number of HSP's gapped (non-prelim): 4203
length of query: 961
length of database: 73,234,838
effective HSP length: 97
effective length of query: 864
effective length of database: 51,435,737
effective search space: 44440476768
effective search space used: 44440476768
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 70 (32.3 bits)
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